LOCUS       DACDAF010000001        76211 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.001, whole genome shotgun sequence.
ACCESSION   DACDAF010000001 DACDAF010000000
VERSION     DACDAF010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 76211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76211
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.001"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..411
                     /locus_tag="IVZ69_000001"
     CDS             <1..411
                     /locus_tag="IVZ69_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP8182122.1"
                     /translation="GLYYSPVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAP
                     QEYLSRAYNDAPKYCANIVNTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLA
                     ELKGYQVTTGEPVCQTRRLNSRIDKVRYMFNKIT"
     gene            509..697
                     /locus_tag="IVZ69_000002"
     CDS             509..697
                     /locus_tag="IVZ69_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP8182123.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(755..1108)
                     /locus_tag="IVZ69_000003"
     CDS             complement(755..1108)
                     /locus_tag="IVZ69_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8182124.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            1639..2061
                     /locus_tag="IVZ69_000004"
     CDS             1639..2061
                     /locus_tag="IVZ69_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP8182125.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            2058..2288
                     /locus_tag="IVZ69_000005"
     CDS             2058..2288
                     /locus_tag="IVZ69_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8182126.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            2786..2986
                     /locus_tag="IVZ69_000006"
     CDS             2786..2986
                     /locus_tag="IVZ69_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP8182127.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            3013..4206
                     /locus_tag="IVZ69_000007"
     CDS             3013..4206
                     /locus_tag="IVZ69_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8182128.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(4274..5839)
                     /gene="guaA"
                     /locus_tag="IVZ69_000008"
     CDS             complement(4274..5839)
                     /gene="guaA"
                     /locus_tag="IVZ69_000008"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP8182129.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(5898..6821)
                     /locus_tag="IVZ69_000009"
     CDS             complement(5898..6821)
                     /locus_tag="IVZ69_000009"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAP8182130.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            7017..7622
                     /locus_tag="IVZ69_000010"
     CDS             7017..7622
                     /locus_tag="IVZ69_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP8182131.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            7930..8946
                     /locus_tag="IVZ69_000011"
     CDS             7930..8946
                     /locus_tag="IVZ69_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8182132.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            9087..10388
                     /locus_tag="IVZ69_000012"
     CDS             9087..10388
                     /locus_tag="IVZ69_000012"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HAP8182133.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            10434..11096
                     /gene="deoC"
                     /locus_tag="IVZ69_000013"
     CDS             10434..11096
                     /gene="deoC"
                     /locus_tag="IVZ69_000013"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HAP8182134.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            11117..11515
                     /locus_tag="IVZ69_000014"
     CDS             11117..11515
                     /locus_tag="IVZ69_000014"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HAP8182135.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            11581..12663
                     /locus_tag="IVZ69_000015"
     CDS             11581..12663
                     /locus_tag="IVZ69_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP8182136.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            12875..14437
                     /locus_tag="IVZ69_000016"
     CDS             12875..14437
                     /locus_tag="IVZ69_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182137.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            14430..15563
                     /locus_tag="IVZ69_000017"
     CDS             14430..15563
                     /locus_tag="IVZ69_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182138.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            15563..16519
                     /locus_tag="IVZ69_000018"
     CDS             15563..16519
                     /locus_tag="IVZ69_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182139.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            16618..17784
                     /gene="deoB"
                     /locus_tag="IVZ69_000019"
     CDS             16618..17784
                     /gene="deoB"
                     /locus_tag="IVZ69_000019"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HAP8182140.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            17808..18626
                     /locus_tag="IVZ69_000020"
     CDS             17808..18626
                     /locus_tag="IVZ69_000020"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP8182141.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            18643..19350
                     /gene="deoD"
                     /locus_tag="IVZ69_000021"
     CDS             18643..19350
                     /gene="deoD"
                     /locus_tag="IVZ69_000021"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HAP8182142.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(19648..20334)
                     /gene="gpmA"
                     /locus_tag="IVZ69_000022"
     CDS             complement(19648..20334)
                     /gene="gpmA"
                     /locus_tag="IVZ69_000022"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP8182143.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(20506..21087)
                     /locus_tag="IVZ69_000023"
     CDS             complement(20506..21087)
                     /locus_tag="IVZ69_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8182144.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(21220..21903)
                     /gene="rpiA"
                     /locus_tag="IVZ69_000024"
     CDS             complement(21220..21903)
                     /gene="rpiA"
                     /locus_tag="IVZ69_000024"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HAP8182145.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            22222..22635
                     /gene="rpsL"
                     /locus_tag="IVZ69_000025"
     CDS             22222..22635
                     /gene="rpsL"
                     /locus_tag="IVZ69_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007085295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HAP8182146.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            22719..23189
                     /gene="rpsG"
                     /locus_tag="IVZ69_000026"
     CDS             22719..23189
                     /gene="rpsG"
                     /locus_tag="IVZ69_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HAP8182147.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            23283..25370
                     /gene="fusA"
                     /locus_tag="IVZ69_000027"
     CDS             23283..25370
                     /gene="fusA"
                     /locus_tag="IVZ69_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP8182148.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            25542..26729
                     /gene="tuf"
                     /locus_tag="IVZ69_000028"
     CDS             25542..26729
                     /gene="tuf"
                     /locus_tag="IVZ69_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP8182149.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            27136..27444
                     /gene="rpsJ"
                     /locus_tag="IVZ69_000029"
     CDS             27136..27444
                     /gene="rpsJ"
                     /locus_tag="IVZ69_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HAP8182150.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            27475..28104
                     /gene="rplC"
                     /locus_tag="IVZ69_000030"
     CDS             27475..28104
                     /gene="rplC"
                     /locus_tag="IVZ69_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HAP8182151.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            28132..28755
                     /gene="rplD"
                     /locus_tag="IVZ69_000031"
     CDS             28132..28755
                     /gene="rplD"
                     /locus_tag="IVZ69_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HAP8182152.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            28755..29045
                     /gene="rplW"
                     /locus_tag="IVZ69_000032"
     CDS             28755..29045
                     /gene="rplW"
                     /locus_tag="IVZ69_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HAP8182153.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            29084..29917
                     /gene="rplB"
                     /locus_tag="IVZ69_000033"
     CDS             29084..29917
                     /gene="rplB"
                     /locus_tag="IVZ69_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010747214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HAP8182154.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            29960..30238
                     /gene="rpsS"
                     /locus_tag="IVZ69_000034"
     CDS             29960..30238
                     /gene="rpsS"
                     /locus_tag="IVZ69_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HAP8182155.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            30261..30608
                     /gene="rplV"
                     /locus_tag="IVZ69_000035"
     CDS             30261..30608
                     /gene="rplV"
                     /locus_tag="IVZ69_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HAP8182156.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            30622..31278
                     /gene="rpsC"
                     /locus_tag="IVZ69_000036"
     CDS             30622..31278
                     /gene="rpsC"
                     /locus_tag="IVZ69_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HAP8182157.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            31281..31715
                     /gene="rplP"
                     /locus_tag="IVZ69_000037"
     CDS             31281..31715
                     /gene="rplP"
                     /locus_tag="IVZ69_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HAP8182158.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            31705..31893
                     /gene="rpmC"
                     /locus_tag="IVZ69_000038"
     CDS             31705..31893
                     /gene="rpmC"
                     /locus_tag="IVZ69_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HAP8182159.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            31918..32184
                     /gene="rpsQ"
                     /locus_tag="IVZ69_000039"
     CDS             31918..32184
                     /gene="rpsQ"
                     /locus_tag="IVZ69_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HAP8182160.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            32242..32610
                     /gene="rplN"
                     /locus_tag="IVZ69_000040"
     CDS             32242..32610
                     /gene="rplN"
                     /locus_tag="IVZ69_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HAP8182161.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            32647..32955
                     /gene="rplX"
                     /locus_tag="IVZ69_000041"
     CDS             32647..32955
                     /gene="rplX"
                     /locus_tag="IVZ69_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HAP8182162.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            32983..33522
                     /gene="rplE"
                     /locus_tag="IVZ69_000042"
     CDS             32983..33522
                     /gene="rplE"
                     /locus_tag="IVZ69_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HAP8182163.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            33541..33726
                     /locus_tag="IVZ69_000043"
     CDS             33541..33726
                     /locus_tag="IVZ69_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HAP8182164.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            33762..34160
                     /gene="rpsH"
                     /locus_tag="IVZ69_000044"
     CDS             33762..34160
                     /gene="rpsH"
                     /locus_tag="IVZ69_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HAP8182165.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            34192..34728
                     /gene="rplF"
                     /locus_tag="IVZ69_000045"
     CDS             34192..34728
                     /gene="rplF"
                     /locus_tag="IVZ69_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HAP8182166.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            34889..35245
                     /gene="rplR"
                     /locus_tag="IVZ69_000046"
     CDS             34889..35245
                     /gene="rplR"
                     /locus_tag="IVZ69_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HAP8182167.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            35266..35766
                     /gene="rpsE"
                     /locus_tag="IVZ69_000047"
     CDS             35266..35766
                     /gene="rpsE"
                     /locus_tag="IVZ69_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HAP8182168.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            35781..35960
                     /gene="rpmD"
                     /locus_tag="IVZ69_000048"
     CDS             35781..35960
                     /gene="rpmD"
                     /locus_tag="IVZ69_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HAP8182169.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            36004..36444
                     /gene="rplO"
                     /locus_tag="IVZ69_000049"
     CDS             36004..36444
                     /gene="rplO"
                     /locus_tag="IVZ69_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HAP8182170.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            36444..37739
                     /gene="secY"
                     /locus_tag="IVZ69_000050"
     CDS             36444..37739
                     /gene="secY"
                     /locus_tag="IVZ69_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HAP8182171.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            37801..38448
                     /locus_tag="IVZ69_000051"
     CDS             37801..38448
                     /locus_tag="IVZ69_000051"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HAP8182172.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            38639..38857
                     /gene="infA"
                     /locus_tag="IVZ69_000052"
     CDS             38639..38857
                     /gene="infA"
                     /locus_tag="IVZ69_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HAP8182173.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            38890..39006
                     /gene="rpmJ"
                     /locus_tag="IVZ69_000053"
     CDS             38890..39006
                     /gene="rpmJ"
                     /locus_tag="IVZ69_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HAP8182174.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            39024..39389
                     /gene="rpsM"
                     /locus_tag="IVZ69_000054"
     CDS             39024..39389
                     /gene="rpsM"
                     /locus_tag="IVZ69_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HAP8182175.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            39417..39806
                     /gene="rpsK"
                     /locus_tag="IVZ69_000055"
     CDS             39417..39806
                     /gene="rpsK"
                     /locus_tag="IVZ69_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HAP8182176.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            39886..40824
                     /locus_tag="IVZ69_000056"
     CDS             39886..40824
                     /locus_tag="IVZ69_000056"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HAP8182177.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            40852..41232
                     /gene="rplQ"
                     /locus_tag="IVZ69_000057"
     CDS             40852..41232
                     /gene="rplQ"
                     /locus_tag="IVZ69_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HAP8182178.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            41504..42343
                     /locus_tag="IVZ69_000058"
     CDS             41504..42343
                     /locus_tag="IVZ69_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP8182179.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMIFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            42319..43188
                     /locus_tag="IVZ69_000059"
     CDS             42319..43188
                     /locus_tag="IVZ69_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP8182180.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            43178..43975
                     /locus_tag="IVZ69_000060"
     CDS             43178..43975
                     /locus_tag="IVZ69_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HAP8182181.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            44178..44924
                     /gene="truA"
                     /locus_tag="IVZ69_000061"
     CDS             44178..44924
                     /gene="truA"
                     /locus_tag="IVZ69_000061"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP8182182.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(45257..47926)
                     /locus_tag="IVZ69_000062"
     CDS             complement(45257..47926)
                     /locus_tag="IVZ69_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HAP8182183.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDGGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(48164..48352)
                     /locus_tag="IVZ69_000063"
     CDS             complement(48164..48352)
                     /locus_tag="IVZ69_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HAP8182184.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            48622..48984
                     /locus_tag="IVZ69_000064"
     CDS             48622..48984
                     /locus_tag="IVZ69_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP8182185.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            49036..50718
                     /locus_tag="IVZ69_000065"
     CDS             49036..50718
                     /locus_tag="IVZ69_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HAP8182186.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            50835..52871
                     /gene="recG"
                     /locus_tag="IVZ69_000066"
     CDS             50835..52871
                     /gene="recG"
                     /locus_tag="IVZ69_000066"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HAP8182187.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            52920..53921
                     /gene="plsX"
                     /locus_tag="IVZ69_000067"
     CDS             52920..53921
                     /gene="plsX"
                     /locus_tag="IVZ69_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HAP8182188.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            54043..54285
                     /gene="acpP"
                     /locus_tag="IVZ69_000068"
     CDS             54043..54285
                     /gene="acpP"
                     /locus_tag="IVZ69_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP8182189.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            54553..55557
                     /locus_tag="IVZ69_000069"
     CDS             54553..55557
                     /locus_tag="IVZ69_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182190.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            55558..56502
                     /locus_tag="IVZ69_000070"
     CDS             55558..56502
                     /locus_tag="IVZ69_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182191.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            56502..57464
                     /locus_tag="IVZ69_000071"
     CDS             56502..57464
                     /locus_tag="IVZ69_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182192.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            57491..58405
                     /locus_tag="IVZ69_000072"
     CDS             57491..58405
                     /locus_tag="IVZ69_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182193.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            58431..60212
                     /locus_tag="IVZ69_000073"
     CDS             58431..60212
                     /locus_tag="IVZ69_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP8182194.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            60560..61246
                     /locus_tag="IVZ69_000074"
     CDS             60560..61246
                     /locus_tag="IVZ69_000074"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP8182195.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            61266..64847
                     /gene="smc"
                     /locus_tag="IVZ69_000075"
     CDS             61266..64847
                     /gene="smc"
                     /locus_tag="IVZ69_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HAP8182196.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            64856..65665
                     /locus_tag="IVZ69_000076"
     CDS             64856..65665
                     /locus_tag="IVZ69_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP8182197.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            65676..66674
                     /gene="ftsY"
                     /locus_tag="IVZ69_000077"
     CDS             65676..66674
                     /gene="ftsY"
                     /locus_tag="IVZ69_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HAP8182198.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            66861..69128
                     /gene="gshAB"
                     /locus_tag="IVZ69_000078"
     CDS             66861..69128
                     /gene="gshAB"
                     /locus_tag="IVZ69_000078"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HAP8182199.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(69217..69669)
                     /locus_tag="IVZ69_000079"
     CDS             complement(69217..69669)
                     /locus_tag="IVZ69_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HAP8182200.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            69819..70769
                     /locus_tag="IVZ69_000080"
     CDS             69819..70769
                     /locus_tag="IVZ69_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP8182201.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            70762..71721
                     /locus_tag="IVZ69_000081"
     CDS             70762..71721
                     /locus_tag="IVZ69_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HAP8182202.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            71718..72473
                     /locus_tag="IVZ69_000082"
     CDS             71718..72473
                     /locus_tag="IVZ69_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8182203.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            72496..73449
                     /locus_tag="IVZ69_000083"
     CDS             72496..73449
                     /locus_tag="IVZ69_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP8182204.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(74093..74389)
                     /locus_tag="IVZ69_000084"
     CDS             complement(74093..74389)
                     /locus_tag="IVZ69_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HAP8182205.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            74744..75100
                     /locus_tag="IVZ69_000085"
     CDS             74744..75100
                     /locus_tag="IVZ69_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP8182206.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            75110..76009
                     /locus_tag="IVZ69_000086"
     CDS             75110..76009
                     /locus_tag="IVZ69_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HAP8182207.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
BASE COUNT        24831 a        13781 c        16342 g        21257 t
ORIGIN      
        1 ggtttatact atagccctgt tagtactcca gcagattttc ggatgcttac tcctattgta
       61 ctggagcaag cctttagaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 gtttatgcac cacaggaata tctttcacgg gcatataacg atgctcccaa atattgtgca
      181 aatatcgtaa atactcaact gaaaaataat gaggtcatta ttattggaga aattcctgct
      241 cgatgtattc aagattatcg caatgattta acttttttta caaatgggct tagtgtttgt
      301 ttagcagagc taaaaggata tcaggttacc actggcgaac ctgtttgcca gacccgtcgt
      361 ctaaatagtc ggatagataa agtaagatat atgttcaata aaataactta gtgcgtttta
      421 tgttgttata taaatatggt ttcttattaa ataagatgaa atattcttta atatagattt
      481 gaattaaagt ggaaaggagg agattgttat tataaactac aagtggatat tgtgtcctat
      541 ttgtggaaat aaaacaagac tacgaatacg agtggatact atacttaaaa atttcccttt
      601 atactgcccc aaatgtaaga acgaaacttt aattaatgtt caaaaaatga atataataac
      661 aatcaaagag ccagacgcca agacgcagag ccgataattt gagaaatgaa actctcatct
      721 tatcggctct ttttgtttat ctgaatttta ctgactagcc ttcaatattt cttgcttcat
      781 tgataccttt tgctagtgct tccattaagg atagttcttt gtctgtaaag ctatccatgt
      841 atttttctac ctgtaacctt cgagtgcttt taatcaaatt atctgtaggt aagaaaaatt
      901 catcaataga tacatggagt aatgatacaa gatcatacag cacttgtgta cttgggtgtt
      961 gtcctttgtt ttctatattt gttaaataac gtgggtcaat ttcaatcatt gttcccactt
     1021 gttcacgagt gagaccccgt ttcattcgag cctctttaat cgctaaacca acggctctaa
     1081 aatcgtattt atcttctttt ttacgcatac taaatcacct ctatacattt tactgttcct
     1141 atataaccat aaacaggtat agaaaaacat gttatatagt ttatgagttc ctatagaaca
     1201 ctgtggaatt tattaatgcg atgaatccaa tttcaaatag aaaggtcgct gattttattt
     1261 acctatacaa ctttataaaa tttagtcata ctcctagaaa gtagataaaa ttggcgactt
     1321 aatggaggga aaagtcgcca tgagaaagat aatctgtcat ctagttctct taattaagtt
     1381 cttatcaaaa aaacttatcc acctgtactg gatagatatg accatcaatg tggttttgca
     1441 gattacatag atagaaaaat caaagcatat gaacagagaa aacaatctgt ttatgtgctt
     1501 ttttggtcac ttaataaata tcttttagga tttctcttca tttatgcaac aaatcccccg
     1561 ttcgtgtcgg ggtttagtat gaagggagat aaagaagcac atgccactcc ctttcacgac
     1621 agaaaggggg tgaaaagcat gaaaccatct tcttttcaag aaaccataga aaatcagttt
     1681 gactatatct gcaaacaagt tattgaagat gaacgaaaag attacttcaa acatctagac
     1741 agactatcag caaaagaagt ctcgttttct gatatagata actaccttgt caactctttt
     1801 tctactgttg atacgtacgt cactgatttc caactattta aattatttgg attaagaatc
     1861 aatgttgaaa gtgatttatt aagtgaagcc ctgcgtcatc tttcagagaa aaaacggaac
     1921 attattttac ttcattactt tatggatatg agtgatgtgg agattgcgga gttactaaat
     1981 ttgaatcgtt cgactgttta tcgtcatcga ataagtggac tagccatgat taaagaattc
     2041 atgaaggagt gtaaagaatg aaaacagctt atccaagggt tcccttcccc ctcattgtaa
     2101 aggcgacaga tggcgacgtg gaagcaatta atcagattgt taaacattat cgagggtata
     2161 cctcaaaacg ttcattacgt cgcatgacag acgaatatgg aaattctcat atggttattg
     2221 atgaaaccct acgtggcaga atggaaacga aactcatctc taagatttta tcgttcgaaa
     2281 ttaaatagtc ccattttttc gtggaagcgt gtcgaatcgt atccacgctt cccgatttgg
     2341 gaggtttgtt attccatcaa agcatattgt gtgttcagta ggttttgata ggctaacaag
     2401 ccaaacgttc tttgacaacc aaataaaggc aatcgaatac gtttcggtaa gaaaagagct
     2461 gatgaactaa cacgccatga cctacaaaat tagtgagcga ttcatgttag taattcgaaa
     2521 gtaatcttta gcaggattgc tgccatgact ttcttatcgt gataatgata ctcccgtata
     2581 gccatagtcc gagcgttaga agcgtcacag gcaatgggta cggctacatg agaaccatgc
     2641 agaagtgaaa ttcctgtgag ctttgctaga gctgttcgat tgctaagata ttcttctctt
     2701 gtcagtgtat tattataaaa ctatttgata taattatagg tgaatattgg agttttccta
     2761 gcctataatt gggaaaggag taataatgat aacggtcaca aaaaaggatt tagttgagct
     2821 aggatatgga acttcttttt cagcagacat cataaaaaaa gcaaaagaat tgatgattac
     2881 aaaagggcat atctactatc aatctcgaaa gctagataga gtccctcgtg aagctgttga
     2941 agaaattcta ggaattcggt tttcaaatga aaacaggtct gagtagtttt tgcacagtaa
     3001 ggagtaaaaa ctatggttaa agacccaata aaaaaagcaa agaatggaac ctattatttt
     3061 cgtgcaaatc taggttatga ttctaaaggg aaaaaaattc aaaaatatcg tagtggattc
     3121 actactaaaa aagaagcaag agaagaatat tcgaaactgc tattgatgaa accagaagaa
     3181 ttaagtgaga ataaggataa aatgacgttt aaacattata tctttgaaat tttccttcca
     3241 tggtataaga cacaggtaaa gctcagaaca tatgaaaatc gcttaccaac tattaagaag
     3301 catttctctt attttgataa aatggctgtt tccgatattg agcctattga tgtgcaaaat
     3361 tggcaactaa aattatcaaa gaagtgtaag tcttcttatg taagagctgt tcaaggacta
     3421 ttttcagttg ctatggatcg agcaattgtc cttgggataa ccaccacaaa tccatctaag
     3481 attattggca atgtgaaaaa gcaaaagtct aaaattgaat tttggacaaa agaagaattt
     3541 gaaaaagtaa tctctctaat ttacaaagaa gattactatc aacacttttt atttatctct
     3601 ctgtggtttt tatttatgac tggaatgcga attggtgaag ctactgccat tcaatgggaa
     3661 gatattgatt ttgactcagg agtactaacc atcaacaaaa cactctatta caagaatcaa
     3721 tcgaattata gatttgttga accaaaaaca aaggcgagcg ttcgtcatat tgtattagat
     3781 aaatgcacat taacttattt atccgaatgg aaggaagtac aacaaaatct aattcagaca
     3841 gactttgtaa tgagctataa cggtattcct acccaaaaac atacactatc atatgctatt
     3901 gaacgctatg ctaagctggc tggtatccat cgaatcagaa tccatgggtt acggcattct
     3961 catgcttcct tgttaatcag tatgggagaa aatccactta tcattaaaga tcgtctagga
     4021 cacgaagata ttgagacgac tttaggaacg tatggacatc tttatcctaa cagtaatttc
     4081 gaggtagcta acaaattaaa tggagccatt tcctttaaag aagcaaaaca aaattatgat
     4141 acttcaccaa agaatcaatt tactgtagac tacttgcgaa acaaagaaat gaaaaaagtg
     4201 caataaaagt gcagtaaaaa gataagaaga gccagaaacc cttggtataa gaggatttct
     4261 agctctccta caactattcc cactccactg ttgctggtgg tttagaagtg atgtcataca
     4321 cgatacggtt gacgtgggct acttcgttta cgatacgtac agagattttt tgcaagactt
     4381 cccatgggat acgggcaaag tcagcggtca ttccgtcgat tgaagttaca gcacggatac
     4441 cgactgtgta gtcgtaagta cgtccgtcac ccataacacc gacagagcgg atccctggaa
     4501 gaacagtgaa atattgccag atatcacggt caagtccagc agctgcgatt tcttcacgca
     4561 agatagcatc agattcgcgt acgatttcta gcttgtcttc agtgatttcg ccaagaacac
     4621 gaataccaag accaggacca gggaatggct gacgccaaac gattgaatca ggcatgccta
     4681 actgagtccc taattcacgg acttcgtctt tgaataatgt gtttaatggt tcgatcaatt
     4741 caaattgcat atcttctggc agtccaccta cattatggtg agatttgatc gtctgtgctg
     4801 tttctgtacc agattcgata acgtcagtat acaacgttcc ttgtgctagg aaagagacgc
     4861 cttcttcacc agcaagtttt gttgcttcgt catcaaaaac atatacgaat tcattcccaa
     4921 tgattttacg tttttgttct gggtcagata cacctttcaa cttgtctaag aagcgatctc
     4981 ttgcatcgac tttgatgatg ttcaagccga attttccgcc tagactttcc attacttgtt
     5041 ccgcttcgcc tttgcgtagc agaccgtggt caacaaagat agatgtcaat tggtcaccga
     5101 tcgctttttg taaaagaacc ccaacgacac tagaatcaac gccacctgaa agaccaagca
     5161 agactttttt gtcaccaact tgttcacgga ttttttctac ttgcatatcg ataaagttat
     5221 ccattgtcca gttaccttca cagtgacaaa catcaaaggc aaagtggcgc agcaattcga
     5281 ttccgtattc ggaatgacgt acttctgcat ggaattggat accataaaaa ttacgtgttg
     5341 tgtcttggat agaagcaatc ggacaatctt tgcttgttcc gactgtttca aagccttcag
     5401 gaactttagt taccaagtca ccatggctca tccatactgt ttgttgtttt ggtgtttctt
     5461 taaacaagac agcttgatcg cttgttactt ctaacaaggc tttcccatat tcgcggtttt
     5521 tagcaggctc tacggaaccg ccaagtttgt acgtgatcaa ttgcatacca tagcaaatcc
     5581 ctaatacagg aatacctaaa ttgaagatct caggatcgat cccaaatgca ttctcatcat
     5641 atacactgtt tggtccgcca gaaagaatga ttccctttgg attcatcgct tttacttctt
     5701 ctgcagtaat gcggtggctc aataattcgg aaaagactcc aagatcacga atacgtcttg
     5761 tgatcaattg gttatactga ctaccgtagt ctaatacgat aatcttttca acgttcgtca
     5821 tatcggcaac gtttgtcaaa tttattaccc ctatcccttt aaattttatc tcaaaatagt
     5881 caaactattt taaaatgcta atattttcgc atgaaaatcg aatcgatgat atgattttca
     5941 gttttatgga gaattatatc ggctcttcct cgtgtaggca agatatattc ctgtaaattt
     6001 ttcaaattca catttttcca tacatctttt gccattttaa aggcttcttc acgatctccg
     6061 atagcaaaac gataataata attctctgga ttttggaaag ccgtatccag taacgcacca
     6121 aaacgatcca aataccattt ttcgatcagc acgggatcgg catcgacata gacagaaaaa
     6181 tcaaaaaagt cgctgacgta gatttgctga ttcgcaggta attgaagcgt attgatcccc
     6241 tcaacgatca agatatcagg ctgctggatc aattcgtact tgtctggaat gatatcatac
     6301 acatcatgtg agtaaacagg tacttttatc tcttcctgac cagattttac acggttcaag
     6361 aaatcgatca gcatctccat atcataactt tcaggaaatc ctttacggtc catgattcca
     6421 cgctctttta atatacgatt tggataaaga aatccgtcag tcgtgatcag ctgaacgttt
     6481 cttcgtttga aggtacgaga caaaatcgtc tgcagcagtc tggctgttgt actttttcca
     6541 acggctacac ttccggcgat cccgataata aaaggcggta cttctacgta tttatgaaga
     6601 aataaacctt tactcaagaa caaagattca aattctttca tataaagata aatcagatga
     6661 gcaagaggta catagatatc tcgaacatcc tgcatggaaa tgcggtcatt caaacttttg
     6721 atattatcta gttcatcttg tgtcaaaggt gcttgcccat tacgataaaa ttctcgccat
     6781 tcttctcttg ccacacggta gtagttcatt ggatcattca tattagcctc ctgcgttctc
     6841 ccatcaatgg aactatttta acacaaaata aacgcaaacc ccaccactta agagagattg
     6901 ccgatctttt tgtataatct ttataataga aagaaacgga gtcttattct tgacttgcgc
     6961 acggatacat aaaaggatag actgttgtca tgaaagaaat gagaaggatg gaagacatga
     7021 caaatcatta ctattctgaa cgcccagata cggcgcacga ttttgaacaa tgggcttttg
     7081 agttaaaagg cagaaccttt caatttgtaa cagattctgg tgtattttca cgtgaaacag
     7141 tggattatgg ttcacgtgtc ctgattgatg ctttcgattg ggaagagtta cctgatgaag
     7201 gaaagatctt agatgtggga tgcgggtatg gaccgattgg gttagctttg gcatttgcga
     7261 cacagcggtt tgttgaaatg gtcgacatta atgaacgagc ggtaagtcta gcgcaaggaa
     7321 acgcaaagcg taaccaaatc gaacatgttg atatccatca atcgaatatc tatgaagcag
     7381 ttcatgaaga aacctatgca gctatcgtaa gcaatccgcc gatccgtgct ggaaaaaaag
     7441 ttgtacatga aattttgaca ggcgcatatc ctcggttgaa gaagggcggt acactgacaa
     7501 ttgtgatcca gaagaaacaa ggagcgccga gtgcgcaaaa gaaaatggaa gaaacatttg
     7561 gtaatgcaga aatcgtcaca aaagataaag gatattatat catcaaaagt gtgaaagaat
     7621 aactagctga aaaatagtgg agcgacgaaa gagtggaact gggcgtgcat gtacgggtac
     7681 gtatcagttc tttttttgtt gagaagtttt taaaaacaaa gaactatttt ttcttcaaaa
     7741 agaaatagta ggaacagagt cgttgttttt tacgataaaa taaataagat acagaacttg
     7801 tatagaaggc tgccaagtcg gtagataaag gaggttttta tcaaaaaaca tactttcctt
     7861 ttttctctat tcttttcttg ggggttttgg tacactgata gggaatttag atagaaggga
     7921 gccaatagga tgaagctgac catcagagat atcgcagaaa tggcaggcgt atcagtaaca
     7981 actgtctcac agattttgaa taacaaagga agcagattta gtgataagac aagaaaaaaa
     8041 gtgttgtcga tcgtgaatga acatcattat aagcccgatt atttcgcttc aaatgtgatc
     8101 aatcgacatt caaagaccat cggaatgatc gtccctgatg tcactgattt cttcttctcc
     8161 aaactgatcg aaggtgtaga gagctatttg aatcctttgg gctatgtgat catgttatgc
     8221 aattctcgtc atagccaaga aaatgagatc aagtatttac aagagctttc ccaccgctca
     8281 gtggacggaa tcttgctggc cacaccaaat attttacctg agaaatatgc attagacagc
     8341 ggtttttatc aaaaaatgcc aatcatttta atcgatcgcg gattgaatcg tcgggataac
     8401 ggacggctta tcgtaaagga atatgagggc gcctatcaag ctgtttcgct gtttattgaa
     8461 aatggccata cgaagatcgg catgctgaag gaaaccactg gatactatca attagaagaa
     8521 cgtttcaacg gatatcgtca tgcgctgaaa gatcatggcc tgccttttaa tgggaaattt
     8581 gttgaacatg gagagttgac tgtccaaggt ggatatactg catcaaaaaa attactcaaa
     8641 cataaagata tcacggctat tttttgcggg aatgatgcca tggcgatcgg atgctatcag
     8701 gcgatcgatg aattgggcaa aaaaatccca gaagatatct cagtcatagg attcgatgga
     8761 ttaaagctgt cagaatacat gattccgcaa ttgacgacag tgcagcagcc aagttttgat
     8821 attggatttt atgctgcacg tttcctgatc gatacgatcg aatttcctca aagaaaagtt
     8881 ccgaacaaag tgttcgaaac aaaattaatt attcgtgaga gcgtaaaagt attgacaaag
     8941 ggctaactcg gcggtatatt gcttatgtaa gcatttacaa aggctagtta gtgctttttt
     9001 tatttttagt aaaccagttt actaaagtgg tttacctttc ctaaaaataa tgtataatac
     9061 cgaatgaaga caaggaggat caggcaatgc gaatggtgga tctgattgaa aaaaagaggg
     9121 atggaaacga gctgtcgaaa gaggaaatcg agtacatcgt cacgaactat acgaatggaa
     9181 agattccaga ttatcaagtc agtgcattat tgatggcaat tttttatcaa gacatgacaa
     9241 atgaagaaat cacgaactta acattggcga ttgctaattc tggtgatgtc atcgatttga
     9301 gttctcttga aggaataaag gtagataagc attcgacagg tggcgttggt gacacgacca
     9361 cattgatttt agccccccta gtagctagtg tcggagtgac agtggctaaa atgtctggac
     9421 gcggtctagg ttacacaggt ggtacactag acaagctaga agcaattccc ggatttcaga
     9481 tcgagctttc ggatgaagaa tttgtacgca ttgttaatga aagtaaagta gcggtaattg
     9541 gtcaatcagg aaacttggca ccggcggaca aaaaattgta tgccttgcgt gacgtcacag
     9601 cgaccgttga ttctcttccg ctgattgcca gttcgattat gagtaaaaaa atcgcggcag
     9661 gagcagatgc aatcgttttg gatgtgacca ctggagacgg tgctttcatg aagaacatcg
     9721 aagatgcaag acgtctggca aagaccatga cgagcattgg gaaactggct aaccgagaaa
     9781 cagtggcggt tatctcagat atgtcagaac ctcttggcga agctatcgga aatagtctag
     9841 aagttgtcga ggcaatcgaa acattacaag gaaatggtcc agaagatcta gtagaaatgt
     9901 gctacgcctt aggaagccaa atggttgttc ttgctggcaa agctaagaca accgatgaag
     9961 caagaacgtt gcttcaagaa gctctggaat caggtaaagc gttagcaaaa ttcaaagaaa
    10021 tgatccaaaa tcaaggggga gacccagcga tcgtggaaca tccagaacga attttgactg
    10081 cacgctacac aatggagctt cctgctaaac aaagcggagt tgtgtcaaaa atcgtggcaa
    10141 atgaattagg aattgctgca atgatgctag gtgctgggcg taaaaccaaa gaagaagata
    10201 ttgatcacgc tgttggattg aaactgcata aaaaaattgg tgacactgtg acaaaaggtg
    10261 agtcactatt gacgatctat agtaacgacg aagaaatcac ttctgtcatt gaattattat
    10321 ataaaaatat tgaaattggt gaatcggcaa tgaagccaac gttgattcat gacatcatca
    10381 cagaataaag gaaaaaagcg gactttaccg ttttaaagaa aaggggaaaa gaaatggaac
    10441 taaaccgaat gatcgaccat actattttga aagcagacgc atctaaagaa gctgtgatgc
    10501 aaattatcga agaagcaaaa aaataccatt tttattctgt ctgcatcaat ccagcatggg
    10561 ttgcgctagc gaaagaacaa ttacaaggtg agccagtagc cgtatgtaca gtaatcgggt
    10621 ttcctctagg agcaaacaca cccgagacaa aagcatttga aacaacagat gccatcaata
    10681 acggtgcaga tgaagtcgat atggtcatca atatcggtgc tttgaaatca aaggatgatc
    10741 aacaagtcca aaaagatatc gaagcagttg ttgaagcagc aaaagatcgt gcgcttgtca
    10801 aagttattat tgaaacatcg ttattagata gagaagaaat catccgagct tgcgaaatag
    10861 caaaagctgc aggcgctgat tttgtcaaaa catcaactgg tttctcaaca ggcggagcaa
    10921 aggtagagga tgtccgtttg atgcgtgaaa ctgtaggacc agaaatgggt gtcaaagctt
    10981 ccggcggtat ccataacgaa gaagaagcaa tggcaatgat cgaagctggt gctacaagaa
    11041 tcggaacaag cgcaggagta gcaatcgtat ctggttcaac tggtgaaggc tattaatttt
    11101 ttcaaaggag aagctcatgg cagaactcaa acaagaatgg atcaacacag ctattgaagc
    11161 gttagataaa gcctatgttc cttattccca ttttccggta ggcgcttgtc tcgtaacgga
    11221 atcaggcaag atttatcaag gcatcaacat tgagaatgca tcatttggat taacgaattg
    11281 tgccgagcgc acagcttttt tcaaagcagt atctgaagga gaaaaaacat ttacgcatct
    11341 agtcgtagcg gggcacaccc ccgatcctat ctctccttgt ggtgcatgtc gacaagtaat
    11401 ggcagaattc tgttcccctg atatgccggt tacgctagta ggagacaatg gtgtgacgaa
    11461 ggcaacgacc gttcgtgcac tgctgcctta tgcatttact gaaaaagatc tataactcat
    11521 gttcattcag tcagctgact gttgaaaaat aaaacaatta ttttaggagg ctttacagaa
    11581 atgaaaaaag caaaattatt tggtttaggt gctgtcgcac tagcagcagg gttattttta
    11641 ggtgcatgcg gcaacaacgg ctctactgat tcatccggtg gcaaaagctc atcagacaca
    11701 acaactgcag cattgatcac agacacaggt ggtgtagacg accgttcatt caaccagtca
    11761 gcttgggaag gactagaaaa atgggggaaa gatcaaggac tttcacgagg aaatgatggc
    11821 ttccaatatt tccaatcttc aaatgaatca gattacatcc caaatattga ccaagcattg
    11881 aatgctggat tcaaaacgat ttttggtatt ggttataaac taaaaccagc gatccaagaa
    11941 caagcaacaa acaatacagg tacgaacttt gttattatcg atgatgtcat cgatggatta
    12001 gataacgttg tatctgcaac tttcaaagac aacgaagctt cttatcttgc aggtgttgca
    12061 gcagcttata cgactgaaac aaacgtagtc ggctttatcg gcggtgtaaa aggtgaagta
    12121 atcgatcgtt ttgatgctgg attcaaagcc ggtgttgatg caggtgcgaa agaattagga
    12181 aaagaaatca aagtattgaa tcaatatgct ggtgacttct ctgctccaga taaaggacgt
    12241 tcaattgctc aaggtatgta tgcacaaaac gcagatatca tcttccatgc ttcaggcggt
    12301 acaggtaacg gtgtattcca agaagcaaaa tcattgaacg aatcaggcga caaaaaagtt
    12361 tgggttatcg gtgttgaccg cgaccaatca gacgaaggcg aatacacatt aaacggcgaa
    12421 aagaaaaact tcacattgac atctacactg aaagcagttg gaacagtagt agaagatttg
    12481 gcacaaaaat cagcggacgg taaattccct ggcggcgaac acactgttta tggattgaaa
    12541 gaagacggtg ttggtctaac agaaggacaa ctttctgacg aagcgaaaaa agcagttgat
    12601 gaagcaaaag aaaaaatcat ttcaggtgac gtaaaagttc cagaaactcc tgaagaaaac
    12661 taaaaccatt tctatagcct tgttagacac atgtttgaca aggctatggt ttgattagaa
    12721 caagaattgt tcatttatcc aagctgcctt gtgacagttt ggataaggga acaactccct
    12781 gaagtaatgt ttgtttcaaa agaagaacgc tcactaagcg tgaatcttag tcaatcgttg
    12841 ccctagatag aaatcgttag gatgtgaaaa aaaggtggtt caagaaaata ttgtcataga
    12901 aatgcagaat attaccaaag aatttggaac attcaaggca aatgacaaca tcaatttaca
    12961 agtaaaggca ggagaaattc atgcgttgct tggagaaaac ggtgctggca aatctacatt
    13021 gatgaacgtg ctttccggat tattagagcc gacatcaggg aaaattttga tgcgtgggaa
    13081 agaagtaaag atcacaagtc cgaccaaagc caaccaatta gggattggga tggtccatca
    13141 gcactttatg cttgttgatg cctttactgt aacagaaaac atcgtgttgg gaagcgagcc
    13201 tagtcgcgca gggatgcttg accataaaaa agcacgaaaa gagatccaaa aagtttctga
    13261 acagtatgga ttgtcagtca acccagatgc ttacgttcgt gatatttcag ttggaatgga
    13321 acaacgggta gaaattttaa aaacacttta ccgaggagca gatgtactga tttttgatga
    13381 gccgacagct gtattgaccc ctcaagaaat tgatgaatta atcgtgatca tgaaggaatt
    13441 agtcaaagaa ggcaagtcga tcattttgat tacgcataag ttagatgaaa tcaaagcagt
    13501 agctgaccgc tgtacagtta tccgccgtgg aaaaggaatc ggtacagtca acgttaaaga
    13561 cgtaacctca caacaattag ccgatatgat ggttggaaga acggtttcat tcaaaacgat
    13621 gaaaaaagaa gcgaagcctc aagaagtcgt tttgtctatt gaaaatctag tggtgaaaga
    13681 aaatcgtgga ttagaagccg tgaaaaactt gaacttagag gttcgtgctg gcgaagtact
    13741 tggtatcgct ggaatcgatg gaaacgggca gtcggagttg atccaagctt tgactggttt
    13801 gcgaaaggca gaaagcggac atatcaagct aaaaggggaa gacatcacta ataaaaaacc
    13861 ccgaaaaatc actgaacatg gtgtaggaca cgtgccagaa gaccgtcata aatacgggtt
    13921 agtcctagat atgacattat ctgaaaatat cgcactacaa acctatcatc aaaaacctta
    13981 cagtaaaaac ggcatgctga attattcagt aatgaatgaa catgccagag aattgatcga
    14041 agaatatgat gttcgaacaa cgaatgaact tgttcccgca aaagctttat caggcggaaa
    14101 tcagcaaaaa gcaattatcg ctcgtgaagt cgaccgagat cctgatctgt tgattgttgc
    14161 aaatccaact cgtggactgg atgtaggtgc gatcgaattt attcataaac gtctgatcga
    14221 acaaagggac aaatacaaag cagtgttact gatcagtttc gaattagaag aaattttaaa
    14281 tgtttcggat cgtattgctg ttatccatga aggagaaatt gtcggtatcg ttgatccgaa
    14341 agaaacatct gaaaatgaat taggtctatt gatggcgggc tataccttag aagaagcacg
    14401 aaaagagtta gaaaaggggg ctggcgcaca tgaatgatcg cagcgaaaaa ttccgtaatt
    14461 tattagtgcc tgtactttca gttgttttag gattgatctt aggcgcgata ttgatggctg
    14521 cttttggttt tcagcccatc caaggttatt cttctatgct agatgcagcc cttggttcgc
    14581 aaagagggat aggtgaaacg ttaaggcaag caacgccgtt gatttttaca gcattaggtt
    14641 tttctgtagc taactcagct gggtttttca atattgggct ttctggacaa gcactttgcg
    14701 ggtggatcgt cagtgtctgg gtggcacttg cgtttccaga tctgccaaaa gttgttttgc
    14761 ttccgttatg cgtgatctta ggtgccttag ctggtgcgat ggcagcggct gttccaggtt
    14821 tacttcgagc attttttgga acaagtgaag tgatcgtaac aatcatgatg aactatatct
    14881 tattatacgt aagcacattt gctttacatg aagtgatgcc tgaaagctat cgctcaagtt
    14941 tggactcttc caatatgatc agtcaaaatg cctcactgcg gttaccatgg ttaacacaag
    15001 cttttggcgg ctctcgcgta aactcaggat tatttttagc aatcatcgcg cttattttcg
    15061 tttggctgct gatgaagaaa acgactttag gatttgaaat ccgttctgtt ggattgaatc
    15121 cttttgcttc tgagtatgca ggaatgagta gtaaacgtac gatcgttttg tcgatggtca
    15181 tttctggcgc tttggcaggg cttggcggtg tggttgaagg attaggaacg tatcaaaact
    15241 tctttgttca aacgacttcg ctatctattg gatttgacgg aatggctgtt tccttgcttg
    15301 gttctggatc agcaatcggt attcttttat cagcgatctt gttcagtatt ttgaagatcg
    15361 gtggacttgg catgcagaca ggagcaggtg ttccgtttga gatcgtcaat gtatcgattg
    15421 ctttgattat cttctttgtc gggatcaact tcctgattcg tttcgtcatg gctaaagtct
    15481 tccaagggaa aaaacaagaa gagatcgttg cgacaataga atcgaaacca acgaatcaaa
    15541 accatgaagg gggcgaacta taatgtcgac tatcgaatta attgccttga tccttacttc
    15601 tacactggtt tattcaacac cgctaattct aacgtcacta ggcggaactt tttctgaacg
    15661 aagcgggatc gtaaacgtag ggctagaggg aatcatggtc atgggtgctt ttagttccat
    15721 cgttttcaac ttgacgatga gtccatcact tggttctatg acaccatgga tcgctatttt
    15781 agtgggtggc gtcgtaggta tcctattttc tctgattcac gcagtagcaa cagtcagttt
    15841 gcgtgctgac catattatca gcgggacagt aattaatctg atggcacctg ctttaggtgt
    15901 tttcttgatc aaagcatggt atggtaaagg tcaaactgat aacatcacgc agaatctggg
    15961 gtatttttct ttcccaggat tagcagatat tccggtcatt ggaccaattt tctttaaaaa
    16021 tacattctta cctgcttatt gtgctatttt gattgctgtc ctagcttggg tgatcatctt
    16081 caagacgaaa ttcggcttgc gcctccgttc agttggtgaa aatcctcaag ctgccgacac
    16141 attaggtatc aatgtatatg ctatgcgtta ttcaggcgta ctgatttctg gcttgttagg
    16201 cggtatgggc ggtgctgttt ttgctcagtc gatttccggt aacttttcag ctggtacgat
    16261 cgttggacaa gggttcatct ccatggctgc tatgatcttt ggtaagtgga atcctttagg
    16321 ggcaatgggt gcctcattgt tctttggttt tgctcaaagc ttgagtatca ttggcgcaca
    16381 attaccagtt atttcttcga ttccgccagt attgctgcaa attgctccat atttgctgac
    16441 aatcattgtg ctggttgttt tcttagggaa agcttctggt ccaaaagcaa acgggaagaa
    16501 ctatatcaaa tcaaaataat cttttagcga ataaaaaggg tgggttacgg gaagtgtttt
    16561 tcgtctcgcc ctttttgttt taaaggcaat aaaaataaaa agaaagaagg aataatcatg
    16621 tttaaacgcg tacatctgat cgtcatggat tcagtaggaa ttggagaagc accagatgcc
    16681 gataagttcg gtgatgttgg ttctgataca ttaggacaca ttgcgaaaga agcaggattg
    16741 aacgttccac atttagagca gcttggttta ggaacgatcc gtcctcttga aggtgtggaa
    16801 tcagtgaaag atcatcaagg ctatgcgacg aaattagaag aagtttctgt agggaaagat
    16861 acgatgacag gccactggga aatcatggga ttgaatatca aaactccatt tcgtgtgttt
    16921 cctaatggat tccctgatga tctgatcaaa caaatcgaag aattttctgg ccgtaaagtc
    16981 gtatgtaaca aaccttatag cggaacagct gttattgacg attacggtga acaccaaatg
    17041 aaaacaggcg atttaattgt atatacttct gccgatcctg tccttcagat cgcggcacat
    17101 gaagaaatca ttcctttaga agaattatat cggatttgcc aattcgttcg tgatataaca
    17161 aaagatgatc cgtatatgat tggccgaatc attgcacgtc cgtacgtggg tgaaccagga
    17221 gacttcacac gaacaagcaa tcgccatgat tatgcgttga atccattcgg acacacagtc
    17281 cttgattctt tgaaagaagc aggaaaggac gtgattgctg ttggaaagat caacgatatt
    17341 ttcaacggac aaggaatcac tgaatctgtc cgcacgaaaa gcaatatgga tggcgttgac
    17401 cagctgctga aagttatgaa aaacgatttt tcaggaatca gctttaccaa tttagtagat
    17461 tttgatgcat tatacggtca tcgtcgggat gtagtcggct atgcgcatgc gattgaagaa
    17521 tttgacttac gaattccaga attgcttgaa gcgatggaag aagacgactt gctaatgatt
    17581 acagccgatc acggaaacga tccgacgttt actggtaccg atcatacgcg agaatatgta
    17641 ccgttattgg tttacagtaa aaaaatgaaa gaacaagggg cattgcctca aggatattat
    17701 tcagatattt cagcaacgat tgctgagaac tttagtgttt cttcgactga aaatggcgaa
    17761 agcttcttga aattattaaa ataatctttt taaataggag aaagcaaatg accaagttaa
    17821 gcgagatgtt acaagaaacg acccagttta tccttgataa aggagtaaaa gaaattgatt
    17881 ttggtttgat tctaggttca ggattaggtg aattagcaga tgaaatcgaa gatgctgtaa
    17941 tgatttctta tgatgagatc ccgttctttc ctgtttcgac agtagttggg catgcaggaa
    18001 agctagttta tgggtctctg gcaggcaaga aagtgttagc catgcaaggg agattccact
    18061 actatgaagg tcattccatg caaacagtga cctatccagt acgtgtgatg gccggactag
    18121 gggcccattc agtcattgtg actaatgcat gtggtggtgt caacgaatca tttgtaccag
    18181 gagatttgat gctgattacc gatcatatca attttactgg tgaaaatcct ttgatcggtc
    18241 cgaatgaaga tgcaatgggc cctagatttc cagatatgag tcaagcttat acgcctgact
    18301 atcaagcaac agcaaaagca gcagcagaaa aactaggttt ggatcttaaa gaaggcgtat
    18361 atatgggcta ttctggacca acttatgaaa cgcctgcgga gatccgaatg tctcggacaa
    18421 taggagccga tgcagtaggg atgtcgactg ttccagaagt catcgtagca gctcacagcg
    18481 gattaaaagt gttaggaatc tcttgtatta ccaacttagc agcaggtatg caagcgaatc
    18541 tgagccatga agaagttgta gaaacaactc agagagtcaa acaatctttt aaagcattgg
    18601 ttaaagaaac attgacatta ttgtaatagg aggaacaata aaatgagtgt gcatattgaa
    18661 gcgaaagaag gcgagatcgc cgataagatt ttacttccgg gagatccttt gcgagctaaa
    18721 tatattgcgg agactttttt ggaagatcca gtttgttaca atcaggtacg cggtatgtta
    18781 ggctttaccg gcaaatataa aggagaacgt atttctgttc aaggaacagg aatgggaatg
    18841 ccatcagcca ccatctatgc ccatgaattg atccagtcgt atggtgtaaa gaaattgatt
    18901 cgagtaggta catgcggtgc attgtcaaaa gacgtccatg ttcgtgattt agtactagca
    18961 caaggtgcag cgaccagttc ttcgatgatc gaaaaaaatt tccaagcctt tcattttcct
    19021 ccaatcagtg atttcaatct attactgaaa gcatatgaga tagctaaaga aaagggctat
    19081 acggttcatg taggaaatgt tctttcggaa gattctttct acaaagatga tttgacagag
    19141 acgttccaat tagctgaact tggcgtttta ggagtggaaa tggaagcagc ggctctttat
    19201 tacttaggcg cgaaatacca tgtgcagaca ttaagtttga tgaccgttag cgaccatttg
    19261 atcaccggtg aagaaacaac agctgcagaa cgtcaatcta cgttcaatga aatgatcgaa
    19321 gtaggattgg aaacagcgat agcagaataa gaaggaaatg aaaaagctgc cctgcattaa
    19381 gtaataagaa catccaagca aaaatagctc ctcatgtttt tgacttggct ggacttatta
    19441 ttgcaaatgt aagcttttga acaccgttta ccaagaggtt gtgaatctgc cgtttaactc
    19501 tgagtcacaa ggaacaattt caaaaaacag cttttcatgt ttgatgaata ttgtgacttg
    19561 tgaccgagaa gttggcagga gaaaaccgtt tatacgaaaa aagggactgt gacaaatcgt
    19621 gtcacagtcc cttttttata gtgtttttta taggtagtat tttttagcaa ctgttaagtc
    19681 atcatttaat tcataaacaa gtggttgacc tgttggaatt tcaagatcca tgatgtcttc
    19741 gtcagagata ccttcgatat gtttagctag ggcgcgtaat gagttaccat gtgcagctac
    19801 taaaacagtt ttgttgtcta gtaatgctgg agcaatttca tcttgccaga atggcaaagc
    19861 gcgttctaat gtcactttca agttttctcc accaggaata tcgcgtttgt ctaacattgc
    19921 gtaacgacgg tcatttgctg cagaaccttc gtcagtttct tccattaatg gaggaagagt
    19981 atcgtaagaa cgacgccaga tgtgcacttg ttcgtcgccg tatttttcag ctgtttcttt
    20041 tttgttcaaa ccttgtaatt taccatagtg acgttcgttt aagcgccatg atttgatttg
    20101 tggtacccaa agttgatctg aatattctaa gatcaagtta catgttttga ttgcacgagt
    20161 taaaacagaa gtgtaagcaa catcaaattc gattccagct tctttgattt tgcgtccgcc
    20221 ttcttttgct tcttcgattc cttctggtgc tagatttaca tcagcccaac cagtaaattg
    20281 gttcaatgca ttccattcac taagaccgtg acgagaaaaa actaattttg gcatgtttag
    20341 ctctcctttt aagataggtt tatatttctg aaattttcag ttctgtttta ttgtacaatt
    20401 ttttggaaga gatttccatc gaaaaattag ataagattct atgagaaaac aagtagagaa
    20461 tataaaaaaa cgaacagtgc ccacgcaact gttcgttttt aggtattaga tgcataattg
    20521 ctcgatttct ttttcaggta aattgatata tttataacat gttccaactg aaacaccgca
    20581 ttttgaagaa ataaattgga tcgtttcttt tttttcataa tagagacgtc ggattttttt
    20641 gatcgttttt gcatcgattt ttggtcttcc gccgattttt ccttttttac gagcttcatc
    20701 taatccaact aatgtacgtt ctttgatcaa tgcgcactcc atgtttgcta ggttttccat
    20761 taattggaaa tagatttttc ccatttcgcg cgtatcgatt ccttcatcaa gactaatcaa
    20821 gtgcagcccg cgatctttga ataattgcgt gagttctgtt aattgccgcg tagatttgcc
    20881 taatcgatga agttggcaaa tgactagtgc atcgccttgt tgcatgtcag cgatcactga
    20941 ctccaaatga acagcagtag aatcattttg ttccacttca tatgtctcat ggaaaatttc
    21001 ttgacaacca aagtcagata attgatcaac ctgagttgtt aaatcaacgt catttatggt
    21061 tgtgcgtgca taaccaataa ttttcatggt gattcctttc tagcagtgat tttctaactg
    21121 gatataacag taaaaatgta gcataaagta cgtcaaaaag atagtttttt cgcaaatttt
    21181 ccgctgtctt tttttattgg atgatcaagc agtttttctt tatttacgac ggattgcgtc
    21241 aagaatctca acgccttttt ctgagccgac aactacttta gaaaccatgt ttaggaaaag
    21301 cccatgttct actaccccaa caagttcatc taaataggta gctaagcttt ctggctgttc
    21361 gatgacttct agatgcagat caatgatgta atgaccacca tctgtggtta agacttctcc
    21421 gttttcgtct gtacgcaaga cgggttggaa tcttttttct tcaaaaatat gaagtagctg
    21481 ttgggagcca taagggatca cttcaactgg gagtgggaac ttcccaagtt tatcgactaa
    21541 tttagaagaa tcaacgatcc aaatcgtttc ttttgagtac gtagcgacta ttttctcgaa
    21601 aagcaaagca gcgccgccgc ctttgatccc ttgaaaatca gcactgattt catcagcacc
    21661 gtctattgtc aaatcgacta cggggacttc atcaatactc tttaacggta ttcctaattt
    21721 ttccgcttgt tcttttgtcg catttgaagt agtaactcct gtgatacgta aaccttcttc
    21781 acgcatacgg cgaccaatct cttctaccat ataataggcg gttgaaccgg tcccgagacc
    21841 tacgatcatc ccgtccttta cgaatttcgc ggcttcaatg ccagctaatt gttttaaatt
    21901 catctttgcg tccacctttt tttagtttga gcatcgtgct ttcctcacta ttttagcgtg
    21961 atttacggta aaaagatacc attctttttt attccaataa agctttttca aaaaaaattg
    22021 catctcttgt tgacatgttt tttcattcgt gatattctaa caaaggtgct ttatctacag
    22081 gtttctgtga agaaacgtgc tgactgttta tcaaagcata tttgataagg atgcagacat
    22141 tgcatttatt ttttatcaca aaaaaagaac cacctggatg tgtggaacta gacgcaaatc
    22201 gtgggaagga ggaaacaagg aatgcctaca attaaccaat tagtacgtaa acctcgtaaa
    22261 tcaaaggtgg aaaaatctaa ttcacctgct ttgaacaaag gatataacag ctttaagaaa
    22321 actcaaacta acgtaaactc acctcaaaaa cgtggggtag caactcgtgt gggtacaatg
    22381 acacctaaaa aaccgaactc agctttacgt aaatatgcac gtgttcgttt gtcaaactta
    22441 attgaagtta ctgcttatat cccagggatt ggtcataact tacaagaaca cagtgttgta
    22501 ttattacgcg gtggtcgtgt aaaagactta ccaggggtac gttaccatat cgttcgcggt
    22561 gctttagata ctgctggtgt taacgaccgt aaacaaagcc gttctaaata cggaactaaa
    22621 aaacctaaag cttaatttta attattaaac aaatgaaact tgcttctact atatagaagt
    22681 aattactatg aacaatattt cggaaggagg agttacggat gccacgtaaa ggtcctgttg
    22741 caaaacgtga tgttttacca gatcctattt ataactcaaa attagtaact cgcttgatca
    22801 accgtgtaat ggttgacgga aaacgcggga ttgcagctaa cattatctat aatgcctttg
    22861 acttgatcaa agaatctaca ggtaacgatc cattagaagt gtttgaacaa gcaatgaaaa
    22921 acgttcaacc tgttcttgaa gttaaagcac gtcgtgttgg gggttcaaac taccaagtac
    22981 cagttgaagt tcgccctgaa cgccgcgtta ctctaggtct tcgttgggta gtaaactacg
    23041 ctcgcttgcg cggtgaacac acaatggaag aacgcttagc aaaagaaatc atggatgctg
    23101 caaacaacac aggtgcttct gttaaaaaac gtgaagacac tcataaaatg gctgatgcca
    23161 accgtgcgtt tgctcactat cgctggtaag attctctctg tttggtcggc ttttataagt
    23221 cgacctcaga tagtgtcctt atttttagca actagatagt aaagagagga gaaacaagga
    23281 gaatgaccag agaattttct ttacaaaaca ctcgtaatat cggtatcatg gcccacatcg
    23341 atgctggtaa aacgactgct actgaacgta tcttgtacta tactggtaaa atccataaaa
    23401 ttggtgaaac tcatgaagga gcttcacaaa tggactggat ggaacaagaa caagaacgtg
    23461 gtattacgat cacttctgct gctactacag cacaatggaa gggtcaccga atcaacatca
    23521 tcgacacacc aggacacgta gacttcacag ttgaagttga acgttcattg cgtgtacttg
    23581 atggtgctgt aactgttctt gatgcacaat caggtgttga acctcaaact gaaacagttt
    23641 ggcgtcaagc aacaacttat ggtgtacctc gtatcgtatt tgcaaacaaa atggacaaga
    23701 tcggtgctga cttcttatat tcagtatcaa ctttacatga ccgtttgcaa gcaaacgctc
    23761 acccaatcca attaccaatt ggtgcggaag acgacttcac aggaattatc gaccttgtaa
    23821 caatgaaggc tgaaatgtat acaaacgatc ttggaacaga gatcgaagaa acagaaattc
    23881 ctgaagaata ccgcgaatta gctgaagaat ggcgcgaaaa attggttgaa gctgtagctg
    23941 aaactgatga agaacttact ttgaaatact tagaaggtga agaaatcact gaagctgagt
    24001 taaaagaagg tatccgccgc gcaacagtta acgtagaatt ctacccagta ctatgtggtt
    24061 cagcatttaa gaacaaaggg gttcaattac tattggacgc tgttcttgat tacttgccat
    24121 caccgttaga tatcccagct atcaaaggga ttgaccctaa aactgatgaa gaagtagaac
    24181 gtcctgcaga cgacagcgct cctttctcag ctttagcatt taaagttatg actgacccat
    24241 tcgtaggtcg tttaactttc ttccgtgtgt actctggtgt tttacaatca ggttcatacg
    24301 tacaaaacgc aacaaaaggc aaacgtgaac gtgttggtcg tatcctacag atgcatgcca
    24361 actctcgttc agaaatctct gaagtttacg ctggagatat cgctgctgct gttggtttga
    24421 aagacacaac tactggggac acactatgtg atgaaaagag tctagttatt cttgaatcca
    24481 tggaattccc agaaccagtt atccaagtcg ctattgaacc taaatcaaaa gctgaccaag
    24541 ataaaatggg tgtggcttta caaaaactat ctgaagaaga tcctactttc cgtgctgaaa
    24601 caaacgtgga aacaggcgaa acaatcatcg ctggtatggg tgaacttcac ttagatatca
    24661 tcgttgaccg tatgcgtcgt gaattcaaag ttgaagctaa cgtaggtgcg cctcaagtat
    24721 cttaccgtga aactttccgt gctggcactc aagccgaagg taagtttgta cgtcagtctg
    24781 gtggtaaagg tcaatacggt cacgtatgga ttgaatttac accaaatgaa gaaggtgctg
    24841 gtttcgaatt tgaaaatgcg atcgtcggtg gggttgttcc tcgtgaatac attccagctg
    24901 ttgaaactgg tttgaaagat gctatggaaa atggtgtctt agctggctat ccattagtag
    24961 atatcaaagc taaactttac gatggttcat accatgatgt cgattcaaat gaaactgcct
    25021 tccgtgttgc tgcttctatg gcattacgtg cagcagctaa gaaagctaat ccagtaatcc
    25081 ttgaaccaat catggctgta gaagttgtta tccctgaaga ttatttaggt gatgttatgg
    25141 gtcacgtaac tgctcgtcgt ggacgtgttg aaggtatgga agctcgcgct ggcggccaac
    25201 aagttgttcg tgcgatggtt ccacttgctg aaatgtttgg ttatgctaca actcttcgtt
    25261 ctgctactca aggtcgtggt acatttacaa tgacatttga ccactacgaa gatgtaccaa
    25321 aatcagtaca agaagaaatc attaagaaaa acggcggaaa agctgaataa tttcttaaaa
    25381 ccggatagtc ctgcaaagag attatccaaa gagactatat ttttaatata gtttcgtgta
    25441 aaataattat cgatgatatg ggcatgtggt gtaccttgtg tacatcatat acctatcaga
    25501 caaataaaaa atatattgta tttttaggag gacattttaa aatggcaaaa gaaaaatttg
    25561 accgttctaa accacacgtt aacattggta ctatcggaca cgttgaccat ggtaaaacta
    25621 cattaacagc tgcaatcaca actgtactat ctaagaaaaa cggcggccaa gctatggctt
    25681 acgatcaaat cgatggtgct ccagaagaac gcgaacgcgg aatcacaatc tcaacagctc
    25741 acgttgagta tgaaacagat acacgccact acgctcacgt tgactgccca ggacacgcgg
    25801 attacgttaa aaacatgatc actggtgctg ctcaaatgga cggagctatc ttggtagttt
    25861 ctgctgctga cggcccaatg cctcaaactc gtgaacacat cctattgtct cgtcaagttg
    25921 gtgttcctta catcgttgta ttcttgaaca aagtagacat ggttgatgac gaagaattac
    25981 tagaattagt tgaaatggaa gttcgtgacc tattaacaga atacgaattc cctggtgacg
    26041 atgttcctgt agttgctgga tcagctttga aagctctaga aggcgacgct tcatacgaag
    26101 aaaaaattct tgaattaatg gctgcagttg acgaatacat cccaactcca gaacgtgaca
    26161 acgacaaacc attcatgatg ccagttgaag acgtgttctc aattactgga cgtggtactg
    26221 ttgctacagg tcgtgttgaa cgtggacaag ttcgcgttgg tgacgaagtt gaagttgttg
    26281 gtattgctga agaaacttca aaaacaacag ttactggtgt tgaaatgttc cgtaaattgt
    26341 tagactacgc tgaagctgga gacaacattg gtgctttact acgtggtgtt gcacgtgaag
    26401 acatccaacg tggacaagtt ttagctaaac caggtacaat cacacctcat acaaaattct
    26461 ctgcagaagt atacgtgttg acaaaagaag aaggtggacg tcatactcca ttcttcacta
    26521 actaccgtcc acaattctac ttccgtacaa ctgacgtaac aggtgttgtt gaattaccag
    26581 aaggaactga aatggttatg cctggcgaca acgtaacaat ggaagttgaa ttaatccacc
    26641 caatcgctat cgaaaacggt actaaattct caatccgtga aggcggacgt acagttggtg
    26701 ccggtgtcgt tacagaaatc aaagcttaat tcacttaagt tttaaagtaa agcaacattt
    26761 attcggacgt aatcgctcgg aacgaaggtc ttaggatctt tgttccgagc ttttttattt
    26821 attgcaggat caggaaaaaa gacaggagta ttataaatag aagaaacacg aaataaaaga
    26881 gtcagtattt tctaaatgaa actttatgaa aacaaaatgt tttttacaag aaaaagcctt
    26941 gctttgtgag tttatatata ttataatgac aaaggtgcgt ttactttagt gaattgcaca
    27001 gacgtaatca gaatgatttc gtcggctaag aaacgagagg ttgcgacacg cccggacgct
    27061 ttgccacgaa cgagcgtgac ggaaattttc gtggagctat gtctactttt caaaataggc
    27121 gaaggaggga acaagatggc aaaacaaaaa attcgtatcc gtttaaaagc gtatgaacac
    27181 cgtattttag atcaatcagc ggataaaatc gtggaaactg caaaaagaac tggagctagc
    27241 gtgtctggtc caattccatt accaactgaa cgcagtcttt acacaatcat ccgtgcgact
    27301 cataaataca aagattcacg cgaacaattc gaaatgcgta cacacaaacg tcttatcgac
    27361 attgtgaacc caacaccaaa aactgttgat gctttgatga agctagactt accatctggt
    27421 gtaaacatcg aaatcaaatt ataaaactaa aacaaaaata atggaggtgt actcatgacc
    27481 aaaggaatct tagggaaaaa agtgggaatg acacaaatct tcactgaatc tggtgaatta
    27541 attccagtaa ctgttgtaga agctactcca aacgtagtac tacaagtgaa aacaatggaa
    27601 acggatggct acgaagctat tcaagttggt taccaagata tgcgtgaagt tttatcaaac
    27661 aaacctgcga aaggtcatgt tgcaaaagca aacacggctc ctaagcgctt cattcgtgaa
    27721 ttcaaaaatg ttgagctagg agaatatgaa gtaggaaaag aaattacagt agatgttttc
    27781 caagcaggag acattattga tgtaacaggt actacgaaag gtaaaggatt ccaaggggtt
    27841 atcaaacgcc acggacaaag ccgcggacca atggctcacg gttctcgtta ccatcgtcgt
    27901 cctgggtcaa tgggtccagt tgcacctaac cgtgtattta aaaacaaacg tcttgctggc
    27961 cgtatgggtg gcaaccgcgt aactatccaa aacttggaag ttgtacgtgt cgatgcagaa
    28021 agaaatgtta tcttgatcaa aggtaatgtt cctggagcta aaaaatcttt aattactatc
    28081 aaatcagctg tgaaagctaa ataattgtag gaagaaagga ggaactaagg aatgccgaat
    28141 gtagcattat tcaaacaaga tggaagccaa aacggtgaaa tcacacttaa cgaagaaatc
    28201 ttcggaattg aacctaatga aagtgttgtt tacgatgcaa tcgtaatgca acgtgcgtca
    28261 ttaagacaag gaacacacgc ggttaaaaac cgtagcgctg ttcgcggcgg cggacgtaaa
    28321 ccatggcgtc aaaaaggaac aggtcgtgca cgtcaaggat ctatccgctc accacaatgg
    28381 cgtggaggtg gcgtagtctt tggaccaaca ccacgttctt acagctacaa acttcctaaa
    28441 aaagttcgtc gtttagcaat gaaatctgta ttgtcagaaa aagttgctga aaacaacttg
    28501 gtagcaatcg aaggcttgaa cttcgacgca ccaaaaacaa aagaattcaa acaagttctt
    28561 gctaacttat ctatcgactc taaagtattg gttgttctag aaaaaggtaa cgactttgct
    28621 gctttatcag cacgtaactt accaaacgtt tctgtagtaa cttctgataa tgtgagtgtg
    28681 ctagacgttg tatcaaatac aaaagtgtta gcaacacaaa ctgctcttac tcaaattgag
    28741 gaggtgcttg cataatgaac ttactagacg taatcaaacg cccagtgatc actgaaaaat
    28801 caatgcttgc catggatgac aagaaataca cttttgaagt ggacactcgc gcaaacaaaa
    28861 ctttagtaaa acaagcggta gaagctgctt ttgacgttaa agtcaaaaac gtgaacatcg
    28921 tgaacgtacg tgcgaaattc aaacgtatgg gcaaatatgc aggatataca aaaaaacgtc
    28981 gcaaagcgat cgttacattg actgaagatt caaaagaaat ccaattattc gaagctgctg
    29041 aataagcact aatagataac tcattaaatt aggagggaaa aacgtggcga ttaaaaagta
    29101 caaacctacc tcaaatggtc gtcgtaacat gacaggttct gattttgctg aaatcacaac
    29161 atcaacacct gaaaaatcat tgttacaacc attgaaaaac catgctggac gtaacaacaa
    29221 cggccgcatc actgtacgtc atcaaggtgg cggacacaaa cgccaatatc gcgtgatcga
    29281 cttcaaacgt aacaaagata acgttgttgc aactgttcaa acgatcgaat atgatccaaa
    29341 ccgttcagct aacatcgcgt tagtacacta tgaagatgga gtgaaagctt acatcttagc
    29401 acctaaagga ctagaagtgg gtatgaaact tgtttcaggt ccagaagcag atatcaaagt
    29461 cggaaatgct cttccattag aaaacattcc agttggtact gttatccaca acattgaaat
    29521 gaaacctggt aaaggtggac aattgatccg ttctgctggt acaagtgctc aagtacttgg
    29581 taaagaaggc aaatacgtat tgatccgctt gaactctggt gaagttcgta tgatcttagc
    29641 tgcatgccgt gctacaatcg gttctgtagg taacgaacaa cacgaattaa tcaacatcgg
    29701 taaagctgga cgctctcgtt ggatgcgtaa acgcccaact gtacgtggta gcgtaatgaa
    29761 ccctaatgat cacccacacg gtggtggtga aggtaaagct cctatcggac gtaaagcacc
    29821 agtttctcct tggggtcaac cagctcttgg ttacaaaact cgtaacaaaa aagctaaatc
    29881 agacaaactt attgttcgtc gtcgcaaaaa taaataatta ctttgaccat gtgtcgcaca
    29941 ttttgagagg aggttcacca tgggtcgtag tttaaagaaa ggaccttttg tcgatgagca
    30001 tttaatgaaa aaagttgaag ctcaagcagg ggttgaaaag aaaaaagtta tcaaaacttg
    30061 gtcacgccgt tcaacagttt tcccaagttt tgttggatat accatcgcag tttatgatgg
    30121 acgtaaacat gtaccagttt acatccaaga agacatggta ggacacaaat taggtgaatt
    30181 tgcacctaca agaacttatc gtggacatgc tgctgacgat aagaaaacga aacgctaatt
    30241 tgaggggagg ataaatccaa atggcagaac aaatcacatc agctaaagca actgcaaaaa
    30301 cagttcgcac ttcacctcga aaagcccgtt tagtaattga ccttatcaga ggtaaaagtg
    30361 tcgcagatgc aatttcaatc ttgaaattca caccaaacaa atctgctgga atcattgaaa
    30421 aagtattgat gtcagcagtt gcgaatgcag aaaataactt tgacttagat gttgaaaact
    30481 tggtagtaag cgaagctttt gttaacgaag gacctacaat gaaacgtttc cgtcctcgtg
    30541 caaaaggatc agcttctcca atcaacaaac gtacaagtca tatcacggta gtcgtatcag
    30601 aaaaataagg agggataatc agtgggtcaa aaagtacatc caattggaat gcgtgtaggc
    30661 atcatccgcg actgggatgc taaatggtat gctgaaaaag agtatgctga gttcttacac
    30721 gaagatttaa gaatccgtaa atttatttca actaaacttg ctgatgctgc tgtatcaaca
    30781 gttgaaatcg aacgcgcaac aggtcgcgta aacatttcaa ttcacacagc taaaccaggt
    30841 atggttattg gtaaaggcgg ttctgaagtc gaaagcctaa gaaaagaatt aaacaaatta
    30901 actggtaaaa gaatccatat caatatcgtg gaaatcaaaa aaccagatct agatgcaaaa
    30961 ttagtaggtg aaggaatcgc acgtcaatta gaaaaccgtg ttgctttccg tcgcgctcaa
    31021 aaacaagcca tccaacgctc aatgcgtgct ggcgctcaag ggatcaaaac tcaagtatct
    31081 ggtcgtctaa acggagcaga tatcgctcgt tcagaaggat actcagaagg aactgttcct
    31141 cttcatactt tacgtgcgga cattgattac gcatgggaag aagcagatac aacatacgga
    31201 aaactaggag ttaaagtgtg gatctatcgt ggagaaattc ttccaactaa aaaaaacact
    31261 gagaaaggag ggaaataatc atgttagtac ctaaacgtgt aaaacaccgt cgtgaattcc
    31321 gcggaaaaat gcgcggggaa gctaaaggcg gaaaagaagt agcattcggt gaatacggtt
    31381 tgcaagctgt tgattcacat tggatcacaa accgccaaat cgaagctgct cgtatcgcaa
    31441 tgactcgtta catgaaacgt ggtgggaaag tatggattaa aattttccct cacaaatctt
    31501 atactgccaa agcaattggg gtacgtatgg gttctggtaa aggggcacct gaaggatggg
    31561 ttgcaccagt aaaacgtggt aaaatcatgt ttgaaatcgc aggcgttcct gaagaagtag
    31621 ctcgtgaagc gttacgtcta gcttctcaca aattaccaat gaaaactaag atcgtaaaac
    31681 gtgaggaaat gggtggtgaa tcgaatgaag gttaaagaaa tcagagaatt aaccactgcc
    31741 gaaatgcttg atcaagaaaa acaattaaaa gaagaattgt ttaatcttag attccaatta
    31801 gcaacaggtc aattagaaaa cactgcacgt attaaagaag tacgtaaatc gattgcacgc
    31861 atcaaaactg tgttgcgtga acaagctaag taattatgga aggaggccat taagcgtatg
    31921 actgaaggaa gaaatcaacg caaagtttat caaggtcgcg tggtttcaga caaaatggat
    31981 aaaacaatta ccgttgctgt cgaaacaaag aaaaaccacc ctatctatgg caaacgcatg
    32041 aactattcta agaaatacaa agtgcatgat gaaaacaaca cagcaaaagt tggcgacatc
    32101 gtgagaatta tggaaactcg tccattatca gctacaaaac gtttccgttt gttggaagta
    32161 gtcgaagaag cagttattat ctaataacac gagattttcc tatatagatt gaatgcaaaa
    32221 tctgaaagga ggatacacaa cgtgatccaa gcagaaagtc gtttaaaagt cgctgataac
    32281 tcaggcgcac gtgaaatttt gacgatcaaa gtccttggtg gatctggtcg taaaactgct
    32341 aacatcggtg atgtgatcgt tgctacggtt aaacaagcaa cgccaggtgg ggttgtcaaa
    32401 aaaggtgacg tcgttaaagc cgttatcgtt cgaacaaaat caggagctcg tcgtacagac
    32461 ggttcatata ttaaatttga tgaaaatgct gcagtgatta ttcgtgatga taaaagccct
    32521 cgtggaacac gtatctttgg gccagttgca cgtgaactac gtgaaaacaa cttcatgaag
    32581 atcgtttcac tagcaccaga agttttataa tcttgagaca cttatcaaag gaggtgcgaa
    32641 acagttatgt ttgttaaaaa aggcgataaa gttaaagtta tcactggaaa agacaaaaac
    32701 aaagaaggcg ttgtactagc agcgttcccg aaaaaagata aagttattgt cgaaggtgta
    32761 aatgtcgtta aaaaacacca aaaaccttct caagctgctc ctcaaggtgg aattgttgag
    32821 atggaagcgc caattcatgt ttctaacgtg atggtggttg actctactgg tgtagctggc
    32881 cgagttggct acaaagaagt agacggcaaa aaagtccgtg tttctaaaaa aaccggtgaa
    32941 gttttagata aataaaagtt taaggaagga gggtcttact gaatgaaccg cctaaaagaa
    33001 aaatatctta aagaagtaac tccatcattg atggaaaaat ttaactatag ctctgttatg
    33061 caaacaccta aagttgaaaa aatcgtcatc aacatgggtg ttggtgatgc ggtatcaaac
    33121 gctaaaaact tagataaagc agttgaagaa ttaactttga tcactggtca aaaaccaatg
    33181 attacaaaag ctaaaaaatc aatcgctgga ttccgtttac gtgaaggaat gccaattggt
    33241 gcaaaagtta cattgcgcgg agaaagaatg tacgaattct tagacaaatt ggtttctgtt
    33301 tcactaccac gtgtacgtga cttccatggt gtaagtaaaa aagcctttga cggtcgtgga
    33361 aactatactt taggtattaa agaacaattg atcttcccag aagtagatta tgatttagta
    33421 gataaagtac gtggtatgga catcgttatt gtaacaacag caaactctga tgaagaatct
    33481 cgtgagttgt tgacacaatt aggcatgcca ttccaaaaat aattaaagga ggcgaactac
    33541 gtggctaaaa aatcaatgat tgctaaaaac aaacgtcctg caaaattttc aacacaagct
    33601 tatactcgtt gcgaacgttg cggacgtcca cattcagttt atcgtaagtt ccatctttgc
    33661 cgtatttgct tccgcgaact tgcctataaa ggtcaaattc ccggcgtgaa gaaagctagc
    33721 tggtaaaaag taaattcgca taagaaggag gtaaaagatc aatggtcatg acagatccaa
    33781 ttgcagattt tctaactcgt atccgtaacg caaacatggt taaacatgag tctttagaag
    33841 tacctgcatc aaaaattaaa cgtgacatcg ctgaaatctt gaaacgtgaa ggtttcgttc
    33901 gtgatgttga atacatcgaa gatgacaaac aaggcgtgat ccgtgttttc ctaaaatttg
    33961 gtaaaaacgg cgaacgtgtt atcacaaact taaaacgtat ctctaaacca ggtttgcgtg
    34021 cttatgtcaa agctgacgaa gtaccaaaag tattgaacgg tttaggtatc gcaatcattt
    34081 cgacttctga aggtgttgtc actgataaag aagctcgtga aaaaaatatc ggcggcgaag
    34141 ttatcgctta cgtatggtaa tcaagtagaa tctacaagga ggtgtcttta agtgagccgt
    34201 atcggaaata aagtcgttgt tatccctgaa ggagtaacag ttactcaaga cggaaacaac
    34261 gttacagtta aaggaccaaa aggtgaattg actcgtactt tttcagcaga tatcaaaatg
    34321 aatatcgaag gaaacgaagt aactttcact cgtccaaacg acagtaaaga aatgaaaaca
    34381 attcatggaa caactcgtgc gaacttcaac aacatggttg taggtgtcag cgaaggtttc
    34441 caaaaagcgt tagaactaat cggggttggg taccgtgcac aattacaagg atcaaaactt
    34501 gtattgaacg ttggttactc acatccagta gaaatcacac caccagctgg agtaactgtt
    34561 gaagtaccag ctaacacaca agtaattgtt aaaggtgcga acaaagaaga agttggcgaa
    34621 ttagctgcaa acattcgtgg aactcgtcct ccagaacctt ataaaggtaa aggtattcgt
    34681 tatgttggcg aatatgtacg ccgtaaagaa ggtaaaactg gtaaataatc gtttagaaaa
    34741 attgcataga agccagcagc aggaaaaagg catttggctg aagtttacct tcaaaaaaat
    34801 acatttttac ttgtgccgca gcttctattt ttcgaaacgt atttactgct tgaaatagta
    34861 gtacaataaa aataaagagg tgacaattgt gattacaaaa ccagataaga acaaaacacg
    34921 tcaaaagaga catcgtcgtg tacgtaacaa tatctctggt actgctgagc gcccacgctt
    34981 gaacgttttt cgttctaaca aaaacatcta cgctcaaatt attgatgacg tagcgggtgt
    35041 aacgctagca agtgcctcta ccttggataa agaaatttca ggtggaacaa aaacagaagc
    35101 agcacaagct gtcggtaaac tagttgctga acgtgcagct gaaaaaggca ttaaagtagt
    35161 agtctttgac cgtggtggat acctttacca tggccgtgtg caagctttag ctgaagctgc
    35221 tcgcgaaaat ggactagaat tttagaagaa ggaggaatac cattcatggt ttatatcgat
    35281 ccaaaacatt tggaattaga agaccgcgtt gttgcaatta accgtgtaac aaaagttgtt
    35341 aaaggtggac gtcgtctacg ttttgctgct ttagttgttg tcggtgacaa aaacggacac
    35401 gtagggtttg gtacaggtaa agctcaagaa gttcctgaag caatccgtaa agcaattgaa
    35461 gatgcgaaga aaaacttagt tgaagtacct atggttggtt caacaatccc acacgaagta
    35521 atcggtgctt ttagtggtgg tagaatccta atgaaacctg ctgtagaagg ttctggggtt
    35581 gctgctggtg gaccagttcg tgccgtatta gaattagctg gggtagcaga tatcacttct
    35641 aaatctttag gctcaaatac accaatcaac gttgttcgcg caacagttga aggtttgaaa
    35701 caattgaaac gtgcagaaga agttgcagaa cttcgcggca aatcagttga agaattaatc
    35761 ggataaggag gacaacaata atggctgaat taaaagttac tttaaaacgc agtattatcg
    35821 gacgtcctca aaaccaacgc gatacagtta aagcgttagg tcttacaaag attaacagtt
    35881 cagtggttaa gccttctaat gaagcaatta aaggcatgat caatactgtt tctcacctag
    35941 tggacgttga agaaatttaa tttagaaaaa tcataactag aacattaagg aggtgccaaa
    36001 cctatgaaac ttcatgaatt aaaacctgct gaaggttcac gccaagtacg taaccgtgtt
    36061 ggtcgtggta cttcatctgg taacggaaaa actgccggac gcggacaaaa aggacaaaaa
    36121 gctcgttcag gcggcggtgt gcgtttagga tttgaagggg gacaaacacc attgttccgt
    36181 cgtttaccaa aacgaggatt cacaaacgtg aaccgtaaag actatgcagt cattaatctt
    36241 gatgtattga accgctttga agacggagct gaagtaactc ctgttgcttt agttgaagct
    36301 ggaatcgtga aaaacgaaaa agctggaatc aaagtattag ctaatgggga actaaacaag
    36361 aaattaactg tgaaagcagc aaaattctct aaagcagctc aagaagcaat tgaagcggct
    36421 ggtggatcaa tcgaggtgat ctaatgttta gactattaaa agatgctttt aaagtaaaag
    36481 acattagatc gaaaatccta tttactgtat ttgtgttgtt tgtatttcgc ctaggtgcac
    36541 atattactgt accaggcgta aatgctgctt cattgcaaaa cctttcttct ttgccatttt
    36601 tcaacatgtt gaacttggta agtggtagtg cgatgcaaaa cttttccatt ttctcaatgg
    36661 gggtttcacc atacattact gcttctatcg tcattcagct tcttcaaatg gacatcgtgc
    36721 ctcgatttgt tgaatggtcg aaacaagggg aagttggtcg taaaaaactg aatcaagcga
    36781 ctcgatatct gacattagta ttggcattta tccaatctgt cggtatcact gctggattca
    36841 atcaatacgc tcaattaggt ttcgtgaata atcctaacgt agcaacttac gtaacgatcg
    36901 gtttgattct aacagccggt acgatgtttg ttacttggct aggagaacag atcacagaaa
    36961 aaggtatcgg aaatggcgta tcaatgatca tttttgcagg tatcatttct agattgcctg
    37021 aaagtatcag agaaatttat gaagattact ttataaatat tgatccttca gacatatgga
    37081 aatctgctat ttttgtggcc attttactag tagcggtctt gttgatcgtg acattcgtaa
    37141 catttttcca acaagctgaa cgcaagatcc cgatccaata tacgaaacgc gtagctggcg
    37201 cgcctacaag cagctatctg ccgttgaaag taaatgcagc tggagttatt ccagttatct
    37261 ttgctagttc gtttattgct acgccaaatg ctgttttaca agcattgagc ggtagattcg
    37321 gttctgaaaa ctggtacaaa gtgatgatgg agatctttaa ctataataca gcacctggtg
    37381 ctacgattta tacgattctg atcgttgcct tcactttctt ctacgccttt gttcaagtaa
    37441 accctgagaa attagcggaa aacttgcaaa agcaaggaag ttatatacca agcgtacgcc
    37501 ctggtaaggg gactgaagag tatgtctcaa gattactgat gcgtttaagt acagttggtg
    37561 cagtcttcct tggtttagtg gcattgcttc caatcattgc tcaaatggtt tgggatcttc
    37621 cacaatcaat cggattaggc ggtacaagct tactgatcgt tatcggtgta gctttagaaa
    37681 ctgcgaaaca gttagaaggc ttaatgctga aacgtaaata tgttggattc attgagtaag
    37741 aaagcgtgtt gaggtttccc ctcaacacac gttctcacac atttattagg agggaaaaca
    37801 atgaacctca ttttaatggg gctgccaggc gcaggtaaag gaacacaagc tgaaaaaatc
    37861 attgatgctt atggtattcc gcacatctca acaggagata tgttccgcgc agcgatgcaa
    37921 aacgaaacag ctcttggcct ggaagcaaag tcttatatgg ataaaggtgc attagttcct
    37981 gatgaagtaa caaatggaat cgtgaaagag cgactagctg aaccagatac agagaaaggc
    38041 ttcttattag atggctttcc acgtacgcta gatcaagcaa aagctctgga cgcaatgcta
    38101 aaagatttga ataaaaaaat tgatgctgtc atcgatatcc atgttggtga agaaatcttg
    38161 gtcgaacgtc tagccggccg atttatctgc agcaattgtg gagcaactta ccataaaatt
    38221 ttcaacccta caaaagttga agacacatgt gatcgttgcg gtgggcatga attctatcaa
    38281 agagaagatg ataaacctga gacggttaaa aatcgtctgg ctatcaacat caaaaatagt
    38341 gaaccaatct tggcttatta taaagaacaa ggtttgctaa acactattga tggtgctcgt
    38401 gaaatcgatg ctgtatttgc agatgtacaa aaaatcattg aaaaatagca cgattgcccg
    38461 tagccgactt gcattatgca gttactcttg tcaagttcaa taaattatga tagaatatgt
    38521 cagtccgact tctagagaat cctctagatg atccattttg agaattttga ggtgggaact
    38581 gcagtttccg ccattttatc gtgtgaaaat gcgaaacaag tacaaggagg tactgtgcgt
    38641 ggcaaaagaa gatatgattg aagtcgaagg tacagtcgtc gaaactttgc cgaatgcaat
    38701 gtttaaagtt gaactagaaa acggacacca agttcttgct actgtttcag gtaaaattcg
    38761 tatgcattac atccgtatct tacctggtga caaagtaacg gttgaattgt ctccatacga
    38821 tcttaaccgt ggccgtatta cttatcgctt taaataattg tactccgtaa aactacagga
    38881 ggtattatca tgaaagtaag accatcagta aaaccaatgt gcgaacattg taaagtaatt
    38941 cgtcgtaaag gacgcgttat ggtgatttgc ccagcaaatc caaaacataa acaacgtcaa
    39001 ggataattgg aggtgctata aatatggctc gtattgcagg agtagatatt cctcgtgata
    39061 aacgtgtagt agtttcactt acttatatct atggtattgg taacactact gctaaaaaga
    39121 tcttagctga tgctggtgta tctgaagatg ttcgcgttcg tgaattaacg aatgaacaaa
    39181 cagatgctat ccgtgcagaa gtagataaat taaaagttga aggggatctt cgtcgtgaag
    39241 tgaacttgaa catcaaacgt ttgatggaaa tcggttctta ccgtggaatc cgtcatcgcc
    39301 gtggattgcc tgttcgtgga caaaacacga aaaacaatgc acgtactcgt aaaggcccag
    39361 ctcgcgctat cgctggcaag aaaaaataat tcttaagtga aggaggttaa aacttcatgg
    39421 cagcaaaaaa agtgaatcgt aaacgccgtg tgaagaagaa tatagaagca ggtattgcac
    39481 atatccattc tacattcaat aacactatca tcatgatcac tgatactcac ggaaatgcat
    39541 tagcgtggtc atcagctggt tcattaggtt tcaaaggaag caaaaaatca actccttttg
    39601 ccgctcaaat ggcagcagaa actgctacaa aagcagcaat ggaacacgga ttaaagactg
    39661 ttgaagtaac agttaaagga cctggttctg gacgtgaagc agcaattcgt tcattacaag
    39721 ctacaggttt agaagtgact gcaattcgtg acgtgactcc agttcctcat aatggtgccc
    39781 gccctccaaa acgccgtcgt gtttaatgag tgccgctcat tttgagtttt atcagtaacg
    39841 tcattgaaca agacactttt cgttttgaaa ggggtaaaga taagaatgat tgagttcgaa
    39901 aaaccaagaa tcgcaaaaat tgatgaagaa aaagattatg gcaagttcat cgttgaacct
    39961 cttgaaagag ggtatgggac tactttaggg aattccctac gtcgtatttt attatcttct
    40021 ttgccaggtg ctgccatcac taatattcaa atcgatggtg tactgcatga attctctacc
    40081 atcaaaggtg ttagagaaga cgtcactcaa atcatcttga acattaaagg cttagcgctg
    40141 aaaatgtatg gccaagaaga aaaaaccctt gaaatcgata ttaccggacc tgctacagta
    40201 actgctggcg atattatcgt tgatagtgat gtagaaattc ttaacaaaga tatgtacatc
    40261 tgtagtgtct ctgaaggagc tacgttccat gctcgcttaa cagtgaaacc tggacgtggt
    40321 tatgttcaag cagatgaaaa taaaaaagaa gatatgccaa ttggcgttct tccagtcgat
    40381 tcaatctaca cacctgttcg tcgtgtgaac tatcaagttg agaacacacg tgttggacac
    40441 cgtgaagatt ttgataaatt gacgatggag atttggacag atggttcaat tgaaccgttg
    40501 gaagcaatga gtttgtctgc gaaaatcatg actgaacatt tggatatttt tgtgaactta
    40561 actgatgaag caaaaaatgc tgaaatcatg gtcgaaaaag aagaaacaca aaaagaaaaa
    40621 atgttggaaa tgacgatcga agagttagac ttgtctgttc gctcttacaa ttgtttgaaa
    40681 cgtgcaggaa tcaatactgt acaagaactt acaaataaat ctgagcctga aatgatcaaa
    40741 gtccgtaact taggacgtaa atcattagaa gaagttaaag caaaattgca cgacttaggt
    40801 ttaggtttac gtaaagaaga ttaaaacctt ttacgaagga gggaaaccaa cgtgagttat
    40861 cgtaaactag gacgcacatc tagccaacgt aaagcgatgt tgcgtgattt aacaactgat
    40921 ttattaatca acgaacgtat tgtgactact gaagctcgtg cgaaagaagt tcgctcaact
    40981 gcagaaaaaa tgatcacttt aggtaaacgc ggagatttgc atgcacgtcg tcaagctgcg
    41041 gctttcgtac gtaatgaagt tgccagcgtg cgtgaagaaa atgaggacat cgtcattgaa
    41101 tcagctttac aaaaactgtt caacgatatt gcacctcgtt acgcagaacg tcaaggcgga
    41161 tacacacgca ttttgaagac agaaccaaga cgcggtgatg gtgcaccaat ggttgtctta
    41221 gaacttgtct aaaatcacac taataacatc actttataga tgattctttt agagtgttat
    41281 gatgttggaa gatatttttc cgagtctagc tcagcgctgc tcctcaagcg aatatcgctt
    41341 ggggagtaag cactcatcat aaagtgtttt tttatacctt caattacctg tcatgacaga
    41401 tatgtttgaa ggcataaaaa aacattttaa gcgagaaata attgaaaatt ttgtcttttt
    41461 ttgatagtgt tagtaggaac tttaggatga agaaggagta atcatggagc caattattga
    41521 attagaaaag ataaattata aataccagcc agatgatctt cgccccgcat tgaaagatgt
    41581 ctcctttaca attgataaag gtgagtggat cgctattatt ggacacaatg gttcaggaaa
    41641 atcgacactt gccaaaacga tcaatggatt gcttctgcca gaatcaggga tcgtgaaagt
    41701 gggaaatcaa atattggatg aagaaaatat ttggacgatc cgacagatgg ttggaatgat
    41761 ttttcaaaat ccagacaatc agtttgttgg ttcgacagta gaagatgacg ttgcttttgg
    41821 tcttgaaaat caagggattc ccagagaaga aatgctagtg cgtgtgaaag atgcacttga
    41881 gaaagttaga atggctgagt ttgcttcacg cgagcctgct cgtttatcag gagggcaaaa
    41941 acaacgtgtt gccattgccg gcgtggttgc cttacgacct gatatcatta ttttagatga
    42001 agcaaccagt atgctagatc cagaaggtcg tgaagaagtg atctctacga tcaagaagat
    42061 caaagaagaa agtcaattga ccgttatatc tatcactcat gatattgatg aagcagctaa
    42121 tgccaatcgg atactagtga tgagacaagg cgaacttgtc cgtgaaggta caccaaaaga
    42181 aattttttct gctggtcctg aactgatcga cttaggtcta gatctaccat ttcctgaaaa
    42241 actgaagagc gcactgaaag aacgtggggt tgatgtgccc agtgaatata tgacagaaga
    42301 aaggatggtg gattggttat ggacatccgt tttgaacaag tagacttcac ttatcagccg
    42361 aatacaccat ttgaacaaag agccttattt gacatcaata tgacgatcaa agaaaacagt
    42421 tatactgcat tagtagggca taccggaagc gggaaatcaa ccttacttca gcatttgaat
    42481 gcgcttgtta agccaacaag cggtacagtc catattggag aacgagatat tcagccggat
    42541 acggataata agaatttaaa gcccatccga aaaaaagttg gcatcgtctt tcagtttcca
    42601 gaagcacagc tattcgaaga aacggtagca aaagacattg ctttcggtcc taaaaacttt
    42661 ggtgtcagcg aagaagaagc actagtccta gcaaaagaaa cattagaaca agttgggctg
    42721 gatgaaagct atttggaacg ttcgccattt gaactttcag gagggcaaat gcgtagagta
    42781 gcaatcgctg gtgtgcttgc catgaggccg gaagtacttg tattggatga accaacggca
    42841 ggacttgatc cccagggcag aaaagaaatg atggagatgt tttggcgtct tcataaggaa
    42901 cagcagatca ctattgtatt agttacgcat ttaatggatg atgtagccaa ttttgcagat
    42961 tatgtctatg tgttggaaaa gggacgaatc gttaatagcg gggagccgca agaggtcttt
    43021 caaaacattg aatggctaaa agaaaaacaa ctaggcgtac ctactgccac cgagtttgca
    43081 gaagaattaa tggctaaagg gatgaacttt gctaccttgc ctttgacagc tgaagaatta
    43141 gcagacgcta tcgtccatta tgctggagga aatgcccatg atgaataaat tgatatttgg
    43201 tcgttatatg cctggagatt ccttgatcca tcgattggat ccccgagcta aattattagc
    43261 cagtttttat tttatcggaa tcattttttt agcaaataat tgggaaacgt accttttgtt
    43321 ggcatttttc acattacttt ctgtcttctt gtcaaaagta gatttgaaat tttttatccg
    43381 aggcattcgc ccattgatct ggctaatcct cttcactgta gctttgcagg tcttgtttac
    43441 aagtggcgga gaaacttatt ggagttgggg tgttttccat atcactgaat ttggtgtgat
    43501 gaacggcctc tttattttct gtcgattcgt gttgatcatt tttatgtcga ctctactcac
    43561 gcttactaca ccgcctttgg aattatcgga tgcgattgag tacttgcttc gtccattgaa
    43621 agccgtacgg ttcccagtcc acgaaatttc attgatgctg tcgattgctc ttcgttttgt
    43681 gcctacattg atggacgaaa cagaaaagat catgaacgct cagcgcgctc gcggtgttga
    43741 ttttggtgaa ggaaacctag ttcagaaaat gaaagcagtc attcctttgc tgattccttt
    43801 atttgtcagc agcttcaacc gtgcggaaga tcttgcgact gctatggaag caagaggcta
    43861 caaaggtggg gaaggaagaa cgaaatatcg tgtattgcat tggcataata gagacacgat
    43921 ggttatcatt gcttttgtat tattaactgt gctactgatc tttttaagag gataaacgtt
    43981 cagtgggccg ctatctattc ttttcttgct gatctgtttg caagaaagga tgcaagcagt
    44041 gtatgacaag aaatattagg gtctgtggca gactaaggtc acaggcctct ttcttttatc
    44101 tgaaaagaaa gaacgaaaaa attttataga aaaatcatta ttccagataa ccttttagga
    44161 acaaaggaga gaaaaacatg gtacgttaca aagcaatcat tgcgtacgac ggaacaaatt
    44221 ttaatggatt ccaaaaacag ccaaatgggc gtactgttca agaagaagta gaaaaaacat
    44281 tacaaaaaat ggcaaatgga aaagaaatca cggtctttgg ttcgggaagg acagatgccg
    44341 gagtacatgc gatcgggcaa gtaatccatt ttgattatcc agaggagcgt ccgttagaac
    44401 gaatgcgttt cgcgctagat acccagtcac cagaggatat tgctgtaaga caagtagaaa
    44461 ttgtttcaga agacttccac gcaagatatt tggtcaaaga aaagacgtat caatttcgag
    44521 tggatatagg gaaaccacgc agtccttttc gacgccatta tgcaagttat tttccttacc
    44581 cacttgattt ggaaaaaatt cagcgggcgc ttcctgattt attagggact cacgatttca
    44641 cctctttttg tgcatcagga agctcgatag aggataaaat acgtacgatc tacgaggcta
    44701 agatggaggt aaatgaaaca aaagacgaat tgttgtttac atttagggga aatggcttct
    44761 tgtataagat gatacggatc ttagtaggaa cgcttttgaa aattggcaat ggccgattgc
    44821 ctgaagatag tatcccagat attattgcga aaaaagatcg taatgcagca ggacctacag
    44881 cacaccctga aggactttat ttgtatgaag tgaaatatga ataagaggtt atgatagaag
    44941 tggtcagctt caagaaataa gaaggtattt acgaaaatta cttctcaaaa ttttgcaaaa
    45001 tttcggctta ttttcgaaga agctacttct ggaacaccgt ttaagaaaga ggtcgtgagc
    45061 ctgtcattta actctgagtc acaaagagca atttcaaaaa acagcttctc atctttgatg
    45121 aatatcgtga cttgtggacg aggcgttgat aagtgaatca tctttttgtt acctattttt
    45181 tctgtaacca aaaaacgatg gaacgttgtt ttgattgccc ttggtgcgga cagtctgaac
    45241 aggttccatc gtttctttat tttctacgtc ttcttctgtg tgtgtttcgt ggttgttctt
    45301 ctattgctgg atcaatcgtg ccataaaagg ggcgattgcg gtcaaggtac cagacataaa
    45361 gaataaacaa tgcaatacat aggacaaaaa ggattgcacc tatcgtaaat ccttcaggca
    45421 agtaactgaa agtgacagta tgtttacctg ctggaacttt tatcatcaag aatgcgtctt
    45481 tgaaattgct gaccttgact ggtttcccat caattttagc tttccatcct ttgtcataag
    45541 gaatagttgt caccaacatg gaatcttcag cggtatttac agtcccagaa gcttttctgc
    45601 cagtggcttc catttcgaca cctttttctt tgatctgatt cattgcggct tgataggcta
    45661 caacatctag accaacgact ttaggctcca tgaaacttat ttctttcgtc ccataaaaac
    45721 ttgcagtaaa tgtcactgtt gtctcttgag gataatagcc aagatcatag tattgaccag
    45781 aaatgttgat ttgcgttttt cgcgatgtac cattgacagt gatcgtcgca ctagaacttt
    45841 ctaattgcgc aaaattggtt gggaacaaac ttaagtaagc ttgtgtattt gcaggcacat
    45901 ggacttccca agtgagctct tttggctggt tatctgctgt ttctgagtaa gtgacgccag
    45961 tcgttgtctt tgtgatcgtc gtattcaact gattcttcaa agtaggtgta tagaatgtaa
    46021 aatactgttc atttagacca gacaatgtat tgatcaagtt tgtctgactg gtcaaattat
    46081 ctgtcactgg ctgctcaaca tcattaacgg acaacggtgc agtaaatgct agtggcaatg
    46141 cattgacatt ctgatacagt gtatagtcgc cgctttgacc agcttggcgg aagccatatt
    46201 tactgaacgt gctttcgttt ttagaaatgt tatatttgat tcctgtaaac ccatccatca
    46261 gcaaagtatt attgttataa cggatattca aatttgtccc tcttgaacgg aaacctaatt
    46321 tatccaggta agaggaagaa ttacgatttc ttatagaaga aaacaaactg ataccactgt
    46381 aaccatagtt gatcgaatcg tttgcagata ctggatccag attttccaag cggtaaaacg
    46441 agtcggaatc tttttttgtt tcatttacaa gagctttcaa gtcaggataa ggatcagtat
    46501 ataaactgcg ggaagcataa ttccaatcat caagaatgcc atggatcata ctgttcgtat
    46561 tgaccagtgc ttcagcagac atgatcaata ataacaatat actcagatga ttgaatgaaa
    46621 gttttttatg ctgataaaat cccacagcaa aagcataaat ccctaagaaa accactgtca
    46681 atacaaagga agtcatcgtc acataggtgt agcttccttc aggtttgatg ccccatgcca
    46741 ccgcaaagag agcagctacg accaaaatga ttcctaacaa cagcccacca tcgtcttgtt
    46801 ctatcttttc ccatcctttt cctgcaagca ggagcactaa gaaagagaac agataggcat
    46861 aacggaataa aaacatattc ggtgcatgca taccatgcca gaacaaattc aatggaacaa
    46921 gataaaaact tgcgataagt atggcgaaaa gactgccgta caaaaattta tttttcaacg
    46981 gtactttccg actggcaaaa taaaacagac agaggactaa tggtagcaga cctgcgtaaa
    47041 cgaacggaat cgatccgtat tttgtcgtgt cataaacacc aatcatattt ttcatgatta
    47101 gatccagata agaagtcgct tctgttttca acgtagtgat ctgactcagt gcctcgccat
    47161 ttgaccgaag atccagcact gctggcaata caatgatcat tgaagcgccg cctgccagta
    47221 aagaagtgat accataagga acaatcgttt ttttatattc tgaccagttt gtcaatagac
    47281 gggcgataaa atataagaaa gaaaatacgc caatcataaa acccatataa aaactggata
    47341 aaaacaagag taaataactg ataaataaaa gtttcggccg tttaagatcc ataacacgat
    47401 gaatccccaa aatcactaat ggaagataaa caaatgcatc cagccacatg atgatctccg
    47461 aatgtgcagt gataaatgag atcaatgcgt aactgacgct aagtgcaaca tgcccccagc
    47521 gaggaatctt gaacgtacgt gcaagaaacc aaaaagccaa tccggcacag ccgaccttaa
    47581 gcaaagtcag aacatacagt gcatctggca tcatctggtt tggaaaaaag aacaccagtg
    47641 gcgtgaagat cccgcctaga tagtaagaaa ttaaagataa ataattcaat cctagagaag
    47701 cattccatgt ataaaaaata ctttgctttc caagaagaac atttcggaag ctggcatgaa
    47761 aattagaaaa ctgtgaaaag gcatcacttg ccaaaatact tctgctgctt ccaggataga
    47821 ttccgatact tagataaaca agtgctaaaa tcaaaaacgg aatcaggaaa ctagctgctg
    47881 cgtagcgtcc gttttctcta aagaatgact ttaaattttt tttcatattt attttccacc
    47941 aaatttctat gaagttgtat tcagtttatc atatccttgt ttttctctgc ttaaaaagag
    48001 tctagttttc acaaaaaaat aaaatttaga ataaataact tcataatttg ttcgtataac
    48061 aaaaataaac gcaaaaaaag ggtaggaatc aaaagtccca cccttaaaaa tttttattaa
    48121 ataaaaaacc gttcactatc tgaacggtcc aagtatcatt caattaaacg cgttcaactt
    48181 ttcctgattt caaagcacga gttgacaccc aaactttttt aggttttccg tcgaccataa
    48241 cgcgaacttt ttgtaagtta ggtttaacag tacgttttgt tgagttcata gcgtgtgaac
    48301 ggttgtttcc actttttgtc ttgcgacctg taaagtaaca aacttttgcc atggtaattt
    48361 cctcctttgc cttgatttgg agcaatagaa taattcagct cataccagac taacatatca
    48421 tatagaatgg gaatttgcaa gtacattttc atagatacaa ttgacaattg agaagaataa
    48481 ttgtaaatta aacaaggtta tacctgaaat tttgcaaggt ttttgagtac tttgggtaac
    48541 tgccttttat ttcaagttgc gctatgataa aatatgatag aagaaaaatg ggagtttttt
    48601 acccgttaag gaggctcatt catggctgta aaaattcaaa cgtcagctgg aaccattgaa
    48661 attaccaatg atgtaattgc aacagttgtt ggtggcgccg cgacagatgt gttcggtgtt
    48721 gtaggaatgg ccagcaaaaa tcaaattaaa gataatatta ctgagatttt gcgtaaagaa
    48781 aattactcaa gaggagtagt tgtccgccaa gaagataatg gtattgctgt agatgtttat
    48841 acgattatca gctatggtac gaaaatctct gaagtttccc gcaacgtcca agaaaaagtg
    48901 aaatacaatc tagaggcatt attaggcgta actgccaatt cagttaatgt ctttgtacaa
    48961 ggtgttcgtg tactgccaga ctaggcagga gactggctgg taactcagca gtcgatctga
    49021 aggaggatta tctaggtgag tgtaacagaa ataagtgcaa gccagttcca ggaaatggtc
    49081 caggcaggtg cgaatcgtct gcaagtaaat gcagaatacg tcaattcatt aaatgtattc
    49141 cctgtgccag atggcgatac gggaacaaat atgaatctat ctatgactag tggagctaag
    49201 gcagtagtag attcaacctc agaaaaagta ggagaattag cagcaatgct ttcaaaagga
    49261 ttgctgatgg gtgcgcgcgg aaattccggc gttattttgt ctcaattgtt tcgtggattt
    49321 tctaagcaaa ttccagatgt tgtctcatta aatgcttctg atcttgctgc agccttcact
    49381 catggagttg aaactgcgta taaagcagta atgaaaccag tagaaggaac gattttgaca
    49441 gtagctagag aagcagcgaa agctggagaa aagaaagcaa aaagtactga tgatgtcgtt
    49501 gaagtaatga cagctgttgt aaaaggagca aagcgtgctt tagctaaaac tccagacttg
    49561 cttccagtcc taaaagaagt cggtgtcgta gacagtggag ggcaaggact gctgtttgtt
    49621 tatgagggct ttttaagtgc attgaatgga gaattccaag cggatgaaac atatgaacct
    49681 tctccagcag aaatggatga tatggtcaat gcagaacatc atcgcagtgt ccaaggtcaa
    49741 atggcgacag aagatatcca ttttggttac tgtacagaaa tcatggtaaa aatcggagaa
    49801 ggacctacag tcgatagtac attcgattac gaagaattcc gtaactattt agatggtata
    49861 ggagattctt tacttgtggt caatgatgac gagatcatca aagtccacgt gcatacagaa
    49921 aacccaggag aagtcttgaa ttatggacaa aaattcggtt cattagtcaa aatcaaagtc
    49981 gacaacatgc gcttgcagca tgagacgatt ttggaacacg atgaagaagt gaacgagttt
    50041 gcgaaaaaag aaataccacg tatcccgtat ggtatcgtag cgatcgctgc tggtaaaggc
    50101 gtccaagagc tgtttgaaag tttaggcgct aattatgtta tcagtggtgg acaaacaatg
    50161 aatccaagta cggaagacat tgttaaagcg attcaagaag taaacgcaga taaagtgatt
    50221 gtcttgccaa acaataagaa catcttcatg gcagctgatc aagcagcaga agtagcagat
    50281 atcccagtag cagttgttcc ttcaagaacg atttcccaag gattgacagc tatgctttca
    50341 ttcaatgatc aagcttcttt agaagaaaac aaagaaacga tgacagaaat gttgtctagc
    50401 gttgtgagcg gtcaagtcac tcacgcgatc agagatacct caattgacgg tgtagagatc
    50461 aaagaaggag actttttggg catgatcgat ggaaaaatcc tgatctctaa cccagatatc
    50521 acagcaacag cgttaagtac actagaacaa atgatcaatg aggacacaga gatcgtaacg
    50581 atcttggcag gtgatgaagg aacagttgaa caagcaaatg aatttgctga gaaactaaca
    50641 gaaaaacatc ctgatttgga aatcgagatc caccaaggag atcagcctgt ctatccttat
    50701 ctattttctg ctgaataatt tctgtgtcag aatatctttc taacacagta ttcattcata
    50761 aaaggccttc ggttagtgat caggtatgat cgctgaccaa gtcctttttt tgttaaagga
    50821 gggaggaaaa atttatgcgt tctttagatg atccaatcac tatgctggca ggagtcggag
    50881 aaaaaagagc agctagtctt gccagcttgg gcatccaaac gattgaagac ttactgactt
    50941 attatccttt tcgctacgaa gatattcagg aaagaaatct aaacgagatc caggatcaag
    51001 aaaaggttac tttgaaagga atcgtagtct cgcctcctgt gatgaatcga tttggttata
    51061 aaaaaagccg attgcaattt cgtatgatgc aagaacatga tgtgttcaac gtttcttttt
    51121 ttaatcaacc ttatctaaaa gaaaaagtca ttttatcgga ggaaatcgcc gtatacggta
    51181 aatgggatgc aaagcgtaaa gccttgaacg ggatgaagat tttaggttct caaacaatgg
    51241 atgacttttc gccgatatat cacgtcaaca aatcaattcg tcaaacgaca ttagttgatc
    51301 taatcaaaaa agggtttcaa gaatacggca cattgattga agaaaatctg ccaaacaacc
    51361 ttgtggagaa atatcgactg cttgaccgag cttctgctgt aagaagtatg cattttccaa
    51421 aagaccacga agaaaaccat caagccaaac gacgtgtcgt ttttgaagag ttctttttat
    51481 ttcaaatgcg tcttcaagga ttgaaaaaag cagaaaaagc agaaacgaat ggtttggaga
    51541 tcctttatga tgtccaaaaa ttgaaacaat ttactcaaaa gctacctttt gaactgacaa
    51601 atgcacaaaa acgtgtaacg aatgaaatct gtcgggatct tcgcagtccg cagcatatgc
    51661 agcgactttt gcagggagat gtaggtagcg gaaaaacagt ggttgccgcg attgcgttat
    51721 acgctaccgt tacagcaggt ttccaaggtg cgttgatggt gcctacagaa atcttggcac
    51781 aacaacatat ggaaagcttg caacagctgt ttgatcccaa tgaagtaacc atcgcattga
    51841 ttacggggtc aacgaaagca aaagaacgac gtgagctcct tgaaaaacta gagcaagggg
    51901 aaattaacgt cgtgatcggc acacatgcat tgatccaaga tggagtcgaa tttcagaatt
    51961 taggtctagt tattacggat gagcagcacc gttttggcgt gaaccagcgg aaagtacttc
    52021 gtgaaaaagg ctggcgacca gatgtcttat ttatgacagc gactccgatt cctagaacat
    52081 tagctattac agcatatggt gagatggatg tatctatcat tgatgaactt ccagctggac
    52141 gtatcccgat cgaaacacgc tgggtaagaa cacctcaatt ggacagtgta ctggattgga
    52201 cgaaaaaaga actggcaaga ggacatcaaa tgtatgtcat ctgtccgctg attgaagaat
    52261 cagaagcatt agatgtaaaa aatgcagtgg aaatctatga aaaacttcgt gaactatttg
    52321 caccaaaata tgaagttggc ttgttacatg gtaaaatgaa gaatcaggaa aaagaagtaa
    52381 tcatggaagc cttcaaagac aaccagatgc agatattagt ttcgactact gtaattgaag
    52441 taggggtaaa cgtgccgaac gcgaccgtca tgctgatcat ggatgcggat cgatttggat
    52501 tggcacagct gcaccaactt cgtggacgtg ttggacgcgg aagtgatgct tcctactgta
    52561 tcttagttgc taatcctaaa aatgaactag gtgtggaacg gatgaaaatc atgacagaga
    52621 ccaccaatgg ttttgtacta agcgaaaaag atctggaatt acgtggtcct ggtgaagtat
    52681 ttggcttccg tcaatctggt ctgcctcaat ttgcgattgc tgacttggtg acggatggaa
    52741 atgttttgga ggtagccaga gaagaggctg cagccctttg gcaaataaag gattggcaga
    52801 tgcttcctga gtatcagcct ttagcgcaaa gcctccaaat agaaaatcag gataatcgtt
    52861 atttcgatta gcagactgtg ctatacttta tactgatgac ggaaaaagga gtggaaacaa
    52921 tgaaaattgc cgtagatgca atgggcggag atcacgcacc tcaagcaatt gtagaaggcg
    52981 tggctttagc gcagcaagat tttccagaag tagaattctt actttacgga aaagaagcag
    53041 aaatcaagaa atacttaaca aatgaaaaaa acatcacgat tatccataca gacgaaaaaa
    53101 tcaatagtga tgatgagcca gtaaaagcaa ttcgacgaaa aaagactgca tcaatggtcc
    53161 ttgctgcaca agcagtgaaa aacggtgaag cagatgctgt attttcagca gggaatacag
    53221 gcgcgctact agcagcaggg ttgttcatcg taggacgtat caaaaatatc gaacgccctg
    53281 gcttgatgtc taccttgcca gtagtaggga aagaaggtgc cggtttcgat atgctggatc
    53341 ttggcgctaa cgcagaaaac aaaccagaac atttgttgca atacggtatt ttaggttctt
    53401 tttatgcacg taaagtccga ggtatcggac gtcctcgtgt cgcactctta aacaacggaa
    53461 cagaagcaac aaaaggtagt gaagtgacga aaaaagccta tgaactcctt cagaatgaaa
    53521 caagcttgaa ttttattgga aacgtagaag ctcgtgagct actcaatggt gtggctgatg
    53581 tagtggtcac agatggattt acaggcaacg ctgttttgaa atctattgaa ggaacagcaa
    53641 tgaatatgat gaatctatta aaatctgcta ttctaaatga agggatcaaa ggaaaaatgg
    53701 gcgctatgct tttaaaagac ggcttacgtt ctttgaaagc agaaatggat tattccaaac
    53761 atggcggtgc cgttttgttt ggcttgaaag caccagtcat taaaactcat ggagcaacag
    53821 gccccgatgc tgttcgctat acgatccgcc aaatccacac aatgcttgag acagatgtag
    53881 ttggacaatt agtcgaacaa tttgaaaaaa gcgaagaata gtatttggat atctgaagcg
    53941 atccgttcca ttgaaaaaaa ggtggacatt cctgaaaaat gccagtaaaa ttagccatgg
    54001 tgtaggtaat tgacaagtgt atgattcttg gaggtgaaaa agttgactcg cgaagaagta
    54061 tttaacaaag tagcgaaaat tatttcaaat cattttgaga tagataccga taaagtgacg
    54121 gatgaattga acatcaaaga tgatttaaaa gctgattcaa ttagtattat ggaattcgtt
    54181 ttagagcttg aagatgaatt cggtacggaa atttcagatg aagacgctga acaaattgaa
    54241 acagtcggtg gcgcagtaga ttatatcagc agccatctta aataatttca aataaaagca
    54301 aagaaggata aaaagctgca tgcagctttt tatccttctt tttttaatct ttttgacacg
    54361 taaaagtcat ttttctgata attctggcga taaacagaaa ttatgttgca aagtaaagcg
    54421 gttttctata taattattaa taattcatta cacaaagata agaataacct ttgttataaa
    54481 acgatttatt ctgtgtaatg tcctttttta ttaagaaaaa cttccattta ggaagcagag
    54541 aggggtattc gattgtccga taaccaatta ttagaagttc agaacctaca tacaggattc
    54601 cgactcaaag atgactatta cgatgcagta gatgacgttt catttacttt agacaaaaac
    54661 gagattttag caatcgttgg ggaatctggg tgcgggaaaa gtaccttggc tactacgatt
    54721 atgggattac ttgatcctaa taacacaaaa attacaggtg agattttata taacgatctg
    54781 aatttaatcg acctgaacga aacgctctat aataaaatcc gcggaaatga tatcggaatg
    54841 attttccaag atccgttgtc tgcattaaat cctctcatga gaatcgaaga ccagatcaaa
    54901 gaaggacttt cctatcacac aaagatgaat gcagaacagc gtcaagctcg tgcactagaa
    54961 ttgctagaac aagtagggat tcctaatcct gcgagagttg gacgccaata tccccatgaa
    55021 ctatcaggcg gtatgagaca acgtgtcatc atcgcaatcg caatcgcctg caaacctcca
    55081 atcgtcattg cagatgaacc gacgacagcc ctagatgtaa ccatccaagc acagattctt
    55141 gatttactga aagaccttca ggaagaaaca aaaacaggga tcatcttgat cactcatgac
    55201 ttaggagtcg tagcagaaat ggctgatcga gtggcagtga tgtatggcgg acagttcgtt
    55261 gaagtagcag gtgtaaaaga actgtttgat catcctaagc atccttatac acgctcttta
    55321 ctgaactcta taccacaaga aggaaatcat gatgcagaac tccatgtgat cgaaggtgtc
    55381 gttccttctc tgaaaaacat gcctcgtaaa ggttgtcggt ttgcaccacg tattccatgg
    55441 ataccagcaa gcgatcatga agaagagcct atccttcatg aagtcgcacc gaaccacttg
    55501 gtacgttgct cctgctataa gcatttccac tttagagacg aaaaaggaga ggtgtagatg
    55561 acagaattaa tcacaatcaa agacctgaaa gttcattacc ctattcgcag tggattcttc
    55621 aatcgagtaa cggatcatgt atatgctgta gatggtgtgg attttattat cgaaaaagga
    55681 aagacatatg gtttagtggg agagtctggc tctggaaaat ctactacggg aaaagccgtt
    55741 gtgggattag aaaaggtaac agccggacaa atcatgtatg aaggaaaaga tgtaacgaag
    55801 cgaagcaacc gcaaaaaaat gggttataac aaggatgtgc agatgatctt ccaagattca
    55861 atgtccagtt tgaatcctaa aaagcgagtg ttggatatca ttgctgaacc catccgaaat
    55921 tttgaacggt taagcgatca agaagaaaag aaaaaggtaa aaggactgct agatatcgtt
    55981 gggatgccgg aagatgcgct atataaatat cctcatgaat tttcaggcgg acaacgtcaa
    56041 cgtctaggag tagcccgtgc tgttgctacc aatccaaaac tgatcgtagc cgatgaacct
    56101 gtatctgctc tggatctatc tgttcaagcg caagtattga atttcatgaa acgaatccag
    56161 caagaatacg gcctcagcta tttattcatt tcacatgatt taggtgtagt aaaacacatg
    56221 tgcgacaata tcgcaattat gtacaaaggt cgatttgtag aaatcggtac aagagaagac
    56281 atttataatg acccgcgaca tatctatacg aaacgtctgc tttcagctat tccgcaaatc
    56341 gatgtagaaa atagggaaag ccacaaagaa aatcgacgaa gagtagaaca agagtatatc
    56401 caaaaccaaa aagaatacta tgatgcgact ggtcgagtct acgatttgcg tacgatcaca
    56461 actacacaca aagtggcgtt gaaagatgga ggtgcaagct aatgtggaaa acgattctgc
    56521 gacgtgtttt attgatgatc ccgcaagtta ttattttaag tgttctgatc ttcttattag
    56581 cccaagcgat gccgggggat ccatttaccg gtttgatcaa tccaaatcag gatccggcag
    56641 tgatcgaaca gatgcgacaa gcagctggct tgaatgaccc atggtatgtc cagtacttcc
    56701 gttggatcgg aaatgctttg caaggcgatt ttggtcaaag tttcttatac aaacgctctg
    56761 ttgctgactt gatcggcgaa cggatcatca acactttata tctatcgatc ttgacagttg
    56821 tccttactta tttgattgct gtgcctctgg ggatgcttgc tggccggtat caaaattcaa
    56881 tcttggataa gattgtcgta atctacaact tctttagttt tgctgttcct ttatttatct
    56941 tcggcttgat catgctattt gtttttggtt atcgtttagg ctggttccca acaagtggat
    57001 cacaaacact aggtttgcaa ggtggattta tcactcaatg gatagaccgt ttgaaatata
    57061 ttctgttacc atcaattacc caagcatttt tggcgactgc cgtcacaatc caatatctgc
    57121 gaagtgaagt aatcgattcg aaatcgctcg attttgtcag aacagcccgt tccaaagggg
    57181 taccgacgaa taaagtattc agtcgacata ttttccgaaa tgcagcgttg ccgatggctt
    57241 ctcaaatggg gtatgaaatc acttcgttga ttgctggttc tgtagttatc gaaaagattt
    57301 ttggttatcc gggagtcgga aaactattta ttgattccat cggccaacgg gactataccg
    57361 tgatcacatc cttagtattg attttaggaa tcgcgacgct agtggggaca ttactttcag
    57421 atatcatcat gagtatcgtt gacccgcgta ttcggattca ataaaaccaa tcagaaagga
    57481 gaatggatcg atgagtgaaa aaaacaatac agcagttcaa gaaagtattc ctcctatggg
    57541 gatacgaatg attgctcgag aatttaaaaa agataaaatt gctatttttt cattaggttt
    57601 gctagtggtt ttattattag tgatctttat cggtgcgatg ctgaccgatc aagacaaagt
    57661 gatgtatgtt agtatcttcg acaaatacgc tgcaccagga acagtttcga cacaaggaca
    57721 aaagttcatt ctgggagcag atgaaggcgg acgtgatgta ttaggacaat tgatcatagg
    57781 tgctagaaac tctgttacga tcggatttgc gatcacgatc cttacttcga tcatcggggt
    57841 tggattaggg atcatctctg gctactacgg agggatcatt gacaacatct tgatgcggat
    57901 cgttgatttt atcatgattc taccgatcat gctgatcatt atcgtcttcg tatcgattat
    57961 ttccagatac aatgtctggt cctttatatt catcatgagt gcattttatt gggtagctaa
    58021 agcccgatta ttccgaagca agacattatc tgaagcaaga agagattatg tcagtgcctc
    58081 aaaaacaatg ggaaccaatg attttaaaat catgttccgc gaaatcatgc cgaatctaag
    58141 ttcattaatc attactaatt tgacgatgaa ctttgcggca aacatcggta tcgagacaac
    58201 tttgactttc ttaggtttcg gcttgccggc aaatgtacct agtttaggta cattgatcgg
    58261 ttatgcaagt aacggagaag tcttagtgaa tcggcaatgg atctggttac ccgcatcaat
    58321 ccttatttta gttttgatgt tgagtatcaa ttatgttgga caagcattca agcgttctgc
    58381 agatgcgcgc caacggttag gctagtatag aagcgaaggg ggaaatagga atgaagaaaa
    58441 cgatttttgg atttgcagcg ctgatgtctg ctgtcgttct tgcagcatgc gggggcggag
    58501 gtacagatac ctctggaaac aactctggag gcaacggcaa taacaaagag gaattaactt
    58561 ttccaattgc aacaaaaaat aatgatgatg caatcgaaga cggcgaatta gaagctgcgg
    58621 tcgcaacgga cagtcagttt aaaggattgt tccagtggga gttttaccaa gattcatatg
    58681 atgcagcttt tatggctcct tctcatgaac cgctatttgc aaacgatgac gatttcagaa
    58741 tcacagacga cggagctgca acgcttgatc tagatgaaga tacgaaaaaa gcgacaatca
    58801 aagtaaaaga caacgtcaaa tggtcagatg gtgaagatgt aacggcggac gatgtgattt
    58861 tcccttacga aatcattggg aataaagatt acactggtat ccgttatgac gacactttcc
    58921 gtaacatcgt aggtatggaa gaatatcatg atggaagtgc cgacacaatc tccggaatca
    58981 aaaaaataga cgacaaaaca gttgaaatcg aatataaaga agtaaaccca agcatgcttc
    59041 aatcgggtgg tggtatctgg tcatatgcag caccaaaaca tacgttagaa ggtgtagcaa
    59101 tcaaagatat ggaatcaagc gatcaagtac gtaaaaatcc agtgactttt ggcccttatt
    59161 acatgagtaa tatcgttgca ggagaatcag tagaatactt gccaaacgag cactactgga
    59221 atggtacgcc taaattgaaa aagatcacga tgaaatctgt accgatggca agtgcaactg
    59281 aagcattgaa ctctaaatta tatgatatga ttttccaaat gccaacagat acttacgata
    59341 cctataaaga aattgctggc tatacaaact taggccgtga acaaacttct tatacttatc
    59401 taggattcaa gttaggtaaa tggaatgcag atacaaagag tgtggaatac aatccagatt
    59461 caaaaatggc tgataaatca ttacgtcaag caatgggcta tgcattagat aataatgcag
    59521 taggtgaacg tttctatgca ggtttgagaa gcaatgcgac ttcattgatt cctccagtat
    59581 tccagtcata ccatgatgat gagatgaaag gattcacaca agatctagac aaagcgaaaa
    59641 aactattaga tgatgctggc tacaaagatg tggatgacga tggtttaaga gaagacaaag
    59701 atggaaataa actaacaatc aactttgctt cgatgtccgg tggggaaaca gcgcaaccat
    59761 tggcagatta ctatatccaa caatggaaag aaattggttt ggatgtccaa tacacaacag
    59821 gtcgtctgat cgaattcaat tctttctatg ataaattaga aaacgatgat cctgaaattg
    59881 atgtttacca agctgcttgg aatacaggaa ctgatccaaa tccaagtgga ctatggggac
    59941 caaatgctgc gttcaactac actcgttatg aatcagaaga aaatacaaaa ttgatcaacg
    60001 atatcagttc aagcaaagca tttgatgaag agtaccaaaa agaagcatat caaaaatggc
    60061 aacaatatgc atttgaagaa gcatttgcga ttccaacgtt gttccgtaat gaagtattgc
    60121 cagtcaacga ccgtgtcaaa gactgggatt ggtcttatga tgtaccaaac ccatgggcaa
    60181 atgtttctgt tacagcagat tcacgttcat aatcactaaa aatgaccgaa aaagggcgat
    60241 gtcctttttc ggttttttga tatttttctg tttatttctc taatattcag gtcaaggcgc
    60301 tgatttcatg acttctccaa taaacggtgt tcaaagtcca gtttctcggt attaagtcaa
    60361 atttatgcaa aaatatggaa agccattttc acaaaatttt ttcttcatac tcgaaactaa
    60421 acgaattttt cacaacttct cgtcaatcac taggattatt aaagctttac ttaccttttg
    60481 accgaaccat ttcaaatttg acaaaaaacc agtataataa ggaagtatcg aaaaaatatc
    60541 cataaaagga atgtggaaaa tggacaacca gctgacaaaa gaactaaaag aaaactataa
    60601 catcgttttt cacgatctaa atttgcttga acaagctttt acccattcat cctatgtgaa
    60661 tgagcatcgc aatctgcaat tatcggataa tgagcgactt gaatttttag gagatgccgt
    60721 tttagaactg atggtttctc agtatttatt ccgtttatat cctcatttgc cagaaggaaa
    60781 attgacaaaa acacgagctg cgatcgttcg cgaagacagc ttgtcgaaat ttgccaaaga
    60841 atgtcacttt gatcaatatg ttttgttggg caagggagaa gagaattcag gaggacgtac
    60901 gcgaccagca ttgctttgcg acctattcga agctttttta ggcgcgttat atcttgacca
    60961 gggattcgac acgacccatg cattcatcga aaaagtgatt tttcctaaag tcaaagcagg
    61021 tgctttttca catgagatgg atcataaaac aaaactacaa gaagtcttgc aaaaatcagg
    61081 tgatgtatca atcgaatacc gattgatcaa tgaagaaggt ccagctcatg aacgagtatt
    61141 ttggatcgaa gtttatgtag atgatcaatt gattggcact ggacaaggga aatcgaaaaa
    61201 attagcagaa caagctgcgg cggaaaatgc attggcagca ctgtaaaagt aagtgaggga
    61261 aagctttgta tttgaaacga attgaaatag ccggttttaa atcatttgca gacaagacag
    61321 tcattgattt tgaaaatagc gtcacagcag tggttggacc aaatggcagc ggaaaaagca
    61381 atattacaga ggctatccgc tgggtattag gagaacaatc tgctaaaagt ctgcgaggcg
    61441 gaaaaatgcc ggatatcatc tttgccggtt ccgatacccg taagcagctg aatattgcag
    61501 aagtcacagt gattttagac aatagtgatc attatctgcc attggagtac aatgagatca
    61561 gtgtaacccg ccgttatcga cggactgggg aaagcgagtt tttcatcaat aaacaaagct
    61621 gcagattaaa agatatccaa gaattgttct tagattctgg attaggaaaa gaatcgttct
    61681 caatcatttc tcaaggaaaa gtagaagcga ttttcagtag taaaccggaa gaccgtcgtg
    61741 ggatctttga agaagcagct ggtgtcttga aatacaagca gcggaaaaag aaagcagaac
    61801 agaagctttt tgaaacagaa gacaacctca gccgcgtcca agacatcatc cacgaattgg
    61861 aagaacagtt aactcctttg gccgcccaga gtgaggcagc aaaggagttt ttacggctaa
    61921 aagaaacact gactcaaacc gatgtctctt tgatggttgc tgaaatcaag acagcaaaaa
    61981 aagattggga caacaaacaa gcacagcttg cgaaattcaa tctagaatta ggcaaactat
    62041 ctgagtcgat ccaagaacaa gaatccattt tggcgaagca gcgtaaagaa aatgcgcaag
    62101 ccgatcgtct gatcgaaaaa aatcagcaag tattattaga tctttcggaa aaactgaagc
    62161 agacagaagg acaaaaagat gttttgcagg agcggacaaa gcatacacaa aaaagctcgc
    62221 aagaatatca aacttcatta gcagaagcac aaaaaaaggt taaacatttt gaaaagcttc
    62281 aagaaagctt gatgaaagca gcagcagaaa aagaaacaga gatccaaaaa gctgaagcaa
    62341 atctcataaa aacacagcaa gaattagaaa aataccaaaa atcaacgaaa gaattattgg
    62401 cagaattaag agatcaatat gttgatttga tgcaagaaca agcagctgta ggaaacgaac
    62461 tgaagtatct agaacgtcaa tatatacaag aaacagcaaa aagcaagcag acgttagcca
    62521 agcaatcgga agtagaagca tcagtagacc gattgatctt acaaaaagaa gaattgacac
    62581 aaaagcaggc gcagctaaaa tcatctttaa ctgaaacaaa agagaagtta gaaatgatcc
    62641 aacaaaacgg gaaaaagttc caagaagcat tagcaaaaga acagcctaaa atgtatcaat
    62701 taatgaatca agtccagcag ctacgtgctc gtaagaaaag ccttcaagaa atccaagaaa
    62761 actattttgg tttttaccaa ggggttcgat tggtcttgca gcataaacag cagctttcgg
    62821 gtattgtcgg agcagtggct gaactgatcg atgttcctgc agatttcacg ttagctatcg
    62881 aaacagcttt aggtggggca gcccagcatg tcatcgttga aaatgaaaaa gatgctcggc
    62941 aagccatcac gtatttgaaa cagcaaagag gaggaagagc aacattcctt ccactgacga
    63001 caatcaaacc aagacaatta ccggctcata tattgacaca agcagcagct gtagaagggt
    63061 ttatagggat tgccagtgaa caagtcagtt atcccgatca aatccaaact gtggttcaaa
    63121 acctgctagg aacgatcctt ttagccaaag acttaactag tgccaatgca atcgcgcaaa
    63181 cgatccgcta tcaatatcga gtggtttcct tagaaggtga tgtgatgaat gccggaggat
    63241 ccatgacagg tggagcgaat aaacgaggaa accaaggcag tttgtttgta caaaatcaag
    63301 aattgaaaca gttgactagt gaatttgaag aagcagataa acaactccaa gcacaagaaa
    63361 aaaaagttca ggagctgcaa caagaaacag ctcgtttagc cgaagaacaa gaagttttgc
    63421 gtacacgagg cgaacaatta cgttttgaag aacaagaagc gacaaatcag ctacaaaaca
    63481 tcataaatga acttgaacgt tttgaaaaag aaaagcaaat ctcaactttt gagacacgtg
    63541 aactgcagca gtttatcgaa gattacgaaa agcaaacgaa cgaattgaaa gacaaacaaa
    63601 cagatcttga atcgcaacga caaaaaatcg acgaagaaat caaatcgtta agtcaagaaa
    63661 gcgaccagat ggaagccaga agagcacaag tacaaagtca aaaagcacaa gaacaagcag
    63721 atcttgctgt cttgaaagag cagtttaatc atctgcagat ccagctccgc ggtgcccgag
    63781 tccaaaaagc agaggcaacc gaacgtcaag aagcgataga aaagcagttg gcgacattga
    63841 cagcagactt ttctgatcat gaagtcacag aagaaagttt ggaaaaacaa attaacgaat
    63901 tatctgctca gcgagaaaca ttaaaagccg agttggcaaa agccaaagag cagcgagata
    63961 gaaggcaaaa ggagatcgat aagcttgaag cagtcttggc agagcgtaat cgtgagcaaa
    64021 aagcacgact gtcggaacaa tccaaattag aagtccaaaa agaccgagct gaaatgattt
    64081 tagataatca tttgacctat ctgcagtcag aatatcagct gacatttgag aaagcttccc
    64141 aagactatca agaaacaacc gatatcgaag acagtagaac aaaggtttca tccttaaaag
    64201 aacagattga aaaactggga ccagtaaact taaattcaat cgaacaatac gaacaagtca
    64261 gtgaaagaca tacattctta gcaacacagc gagatgatct gttagcagcg aaaaaccaat
    64321 tgtttgaaac gatggatgag atggatgatg aagtgcggac aagattcaaa gaagtatttg
    64381 aagctatccg tcaagaattc aaaattgtct ttccaaatat gtttggcggc ggtaaagctg
    64441 aattagtact gacggaacca actgatttgc tgaaaacagg tattgagatt gaagtacaac
    64501 ctcctggcaa aaaactgcaa agtctaagtt tgctttctgg aggagaacga gcacttacag
    64561 ccatcgcgtt gctcttttcc attatccgtg tctgtcctgt tccgttttgt atcttagatg
    64621 aggtagaagc agcgttagat gaagccaacg tgaaacgttt tggtcgttac ttgagcgatt
    64681 tccaagatga cacacaattt atcgtagtca cacaccgcaa aggaacgatg gtcgcagcag
    64741 atgtactgta cggagtgacg atgcaggaat ccggtgtatc aaaaatcgtt tctgtacgga
    64801 tggaagatat caatgaagag gcgaaaatca acgaaacgaa agtgtaggaa cgaaaatgat
    64861 caaattagta gcaatcgatt tggacggtac attattaaat gaacaaaagc tgatttcaga
    64921 tgagaataaa caagcattag cacaagcaaa acagcaaggg gtcaagatcg ttctatgtac
    64981 aggacgcccc ttagctgcga tggcgcatta tctgcaagaa ttaggactgg tagatgaagg
    65041 tgactacagc atcactttca acggcggttt ggtacaaaaa aatgatactg gtgaaatcat
    65101 ggaaaagaaa gtgatggaag tatcagatat ccaacgctta tacaaactgg ctcagcaatt
    65161 ggatctgcca ctagatgttt tgtctgacaa tgtggtttta cagctgccta gtgccccaag
    65221 gaagcaatcc ttgtacaatg tgttgaataa gctgctgcaa ttccaaccag cggatataag
    65281 cgatattaca gatgaatttg tgcttaataa ggcagtaatc gcttatgacc aagaagaatt
    65341 agatcctaaa atcaaagaaa taccagcaga attccatgaa atgtatgaga tcatcaaaac
    65401 aagaagtatg cttttggaat ttatgccaaa aggtgttaca aaagcttatg gtatttcttt
    65461 attggcaaaa gatcttggtt tgaaacaaga agaaatcatg gcgatcggtg atgaggaaaa
    65521 tgatttaccg atgatccaat atgctggact aggcgtagcg atggagaatg ctgtgccttt
    65581 cgtcaaagaa gcagcagatt tcgtgacagc cagcaatgaa gaaaatggcg tagccaaagt
    65641 gatccaaaaa tttgtattag agtaggggga gtcaaatggg attttttgat aaaatcaagc
    65701 gtgcttttac tggcgaagag aaaacagaag aagttgaagt acaggagaag tacgacaagg
    65761 gtttagaaaa gacgcgtaaa acatttggtg aacggatgaa tgagttgttt gccaattttc
    65821 gaacagtcga tgaagacttt tttgaagaat tagaagaaac acttatcggt gcagatgtag
    65881 gttttgaaac agcgatacga attaccgaag cattacgtca agaagtgaaa ctcagaaatg
    65941 cgaaaaaatc ggcagaagtc caaaatgcga tcatcgagaa acttgtggat ctctatgaag
    66001 cggaaggaat caatgaagta aatgaactaa atatccaaga agacggacta acagttattt
    66061 tgtttgtcgg tgttaatggt gtagggaaaa caacaagtat tggtaaactt gcccatcagt
    66121 tcaaaaacga aggtaaaaaa gtattgatgg cagcagcaga taccttccgc gctggagcaa
    66181 tcgaccagtt agttgtctgg ggcgaacgcg ctggtgttga agttgttcgt ggcaatgcag
    66241 gaggcgatcc agcagctgtc gtattcgatg ctttggaaag agcaaagaca gagcaggcag
    66301 atgttttact agttgatact gcaggccgac tgcaaaataa agtgaacttg atgaacgaat
    66361 tagaaaaaat aaaacgagta atccagcggg aattaccaga agcaccccaa gaaacacttc
    66421 ttgtattaga tgcaaccact ggtcaaaacg cgatggttca agcaaaacaa ttcaaagaaa
    66481 caacagatgt gaccggtctt gttttgacaa aattagatgg tacagcaaag ggcggtatcg
    66541 tacttgctat ccgtaatgaa ttgcatttac cagtgaaatt ggtcggtctt ggtgaaggaa
    66601 tcgatgactt ggagccgttt gatccaaatg attttgtcgt tggattgttc aaaggattac
    66661 taaaagaaga ataacccatg tctaaaaagc aggagctgtg acaaaagttg cagctccttg
    66721 tttgaatgat tgtttttaac atagctgtgt ttttgatgcc ttcattttta tacttatttg
    66781 taagcggttc tcaaacaatt tcgttctttt tcttagactt tttgattata attagattca
    66841 tatgaattgg aggtcactta atgatgaatt ttaagcaatt attattgcat gtcaatgcgc
    66901 gcccttttat cgaccaagct cgatttggta tagaacggga aggacagcgg gttgatcttg
    66961 caggaaatct agcaaaaacc gatcatccag caatctttgg cgatcgatcc tatcacccct
    67021 atatccaaac agattttagc gaaacacaaa cagagatgat cacccctgtt accgattcta
    67081 ttcccgaatt atttcagtat ctcgctgctg tttatgatgt gactgctcgt tctataccga
    67141 aagaagagat gatctggcca ttaagtatgc cacctgcctt accggaaaaa gacgaagaga
    67201 tcattattgc aaaattaaaa aatttcgaag atgtcttgta tcgacgttat ttagcaaaag
    67261 aatacgggaa gcgaaaacag atggtaagcg gtattcattt caattttgaa tttggcgatg
    67321 agttgctaag aacattgttc agccatcagg aagaatttca agatttttcc gaattcaaaa
    67381 cagaacttta tttgaaaaca gcgagaaact ttatgcgcta tcgctggatg atcacttatt
    67441 tattcggtgc ttcaccaatg agtgagaaga actacttttt agatgaatca catccgcaag
    67501 aacctgttcg cagtattcgc aacagtgcgc tgggctatac gaatcatcca aatgtgaaag
    67561 tttcctatgc ttctatgaaa cagtatttag cagatatcga gcgaatgatc gaagaaggga
    67621 aactttcgga ggagaaagaa ttttatacac cgcttcgttt ccgaggcgga aagaaagtcg
    67681 cagatttagc aacaacaggt gttcgttata ttgaattgcg gaatatcgat ttgaatcctt
    67741 atgcaagatt gggtatcaat ccagagcaag ttcggttctt acaattattc ctgatgtaca
    67801 tgttatggac agaagaaaaa gaagactgtg accaatgggt agcagaaggt acgactcgaa
    67861 ataacaaagt agcactagaa caaccatcag atcaaacaga atttcatcaa gaaggtagag
    67921 aaattcttga aggaatgaag caaatgctgg ttgaattgga ttggttggat tctctttatt
    67981 tagtagagga agcattgact caaatggatc atcctgaaca aacgttagca gcgaaactct
    68041 atcaagaagc acagctatcg agtcagcaag aagttgctgt ggcattggga catcaatatt
    68101 ataaagaaag ccatgaacgt ccctatcagt tggccggttt tcgcgaaatg gaactttcta
    68161 ctcagatatt tatgttcgat gccatccaaa aaggtgtcca agtcaaagta ttagatgagt
    68221 cggatcaatt tttgcgtctg caattccaag accatgtaga atatgtgaaa aatgcaaaca
    68281 tgacaagtaa ggacagctat atcgtcccac ttatcatgga aaacaaaaca gtaacgaaaa
    68341 aagtcttaaa agaagctggg ttccgggtac caggaggcgc agaattttca tccatggaag
    68401 aagcggtaaa agcttatccg agatttgccg agcaggcatt tgtgatcaaa cctaaatcaa
    68461 ccaattacgg gttaggtatc acgattttca aggaaggagc tagtctggaa gattatcaag
    68521 caggtttagc cattgctttt cgtgaagaca gttcggtttt agtagaagaa tttatgccgg
    68581 gaacggaata tcgtttcttt gtgatcgacg gagaagtcca agccatcatg ttgcgagtcc
    68641 ctgctaatgt tattggtgac agtatccgaa cagtgaaaga acttgttgaa gaaaaaaata
    68701 gtgacccttt gcgtggaacg aatcatcgtg cacctttaga attgatccaa ttaggtgaat
    68761 tagaacaatt gatgttgaaa gaacaagggt tgacgatcga atcagttccc caagccaatc
    68821 aaattgttta tctaagggag aactcaaata tcagtacagg tggtgattcg atcgatatga
    68881 ctgatgaatt ttctgaagct tacaaaaaaa tcgccgtttc tgcggtagaa gcactaggag
    68941 ctaagattag tggtatcgat ttgattatac cagataaaga aatcgatcct acaactgata
    69001 aaaaagcata tgggatcatc gaagcaaatt tcaatccagc catgcatatg catgtttatc
    69061 cttttgcagg aaaaggcaga agattgacga tgaatgtatt gaaattgtta tatcctgaag
    69121 tattttaaaa gaaaaagctt ttgacagatt gtcctatttg atgtcaatct gatcaaaagc
    69181 tttttttgca tgtaaaaatt tatgtgtttt ttcgttttaa aataaacgat cccagaagct
    69241 ttttttcttt tttggttttt ctttttcagc tggcgaagag ttttcttctg ggtatttttt
    69301 ttcgatatca atcacaggtt catttactgc ttcttttgct gttaagagca atccgaattc
    69361 ctcaggattt gcagtgacgt aatcgttgac tacagtgaaa cggctattgt ttttcgttgc
    69421 tagctggata tattggtttt ggacagaaag gggtagagcc ccattcaaga gtatggaagc
    69481 atctggatgt tttttgagtt cttttaaaaa gttttctttg ttttttggtt ggatcatttc
    69541 agcaacagtc atactaagat agcagcgttc cctgaatgtc cctaaatatt tatgctgttc
    69601 ttcagggttc actaaaggtg taccataaag tcccttatcc aaatggcttt ttacatcatc
    69661 ttgtgccata aaaaataccc tccttcttct ctttgtcttt cttacgatta tagcatattc
    69721 ccaataatac ctaaaacata tgaaaaagcg gttgcttttg ttcaacgatt cacttaaaat
    69781 aagaatgaaa atcattctca attagaaagg tggattggat gcgctacgga cgactagtag
    69841 cattattagt tattttaagt agtatttcat tgttcatcgg agtatcgaat gtacaattgt
    69901 cagaactgct ccagttagat gggcaaagct tacaaatctt gctagtgact cgtttgccac
    69961 gaacgatttg tttgatcctt gtgggagcga ccagtagtat ttgtgggttg atcatgcaac
    70021 atttgaccca aaataaattt gtttcaccaa cgactgcggg cacgatggat agtgcgcgtt
    70081 taggtatttt agtggctatg attttcctac ctggtgcatc cttgattgtc cgatccttga
    70141 cagcattttg ctttgctttt gcaggaacat tgcttttttt atcccttacg cgattgttcc
    70201 tccagaaaaa tcaattgatg cttccgttga ttggagtcat gttagggaat atcattggtt
    70261 cagttgctac tttttttgct tatcaattcc agttggtaca aaatatgact tcatggcttc
    70321 aagggaattt tgcgactgtg atacgaggaa attatgagtt attgtatgct gttgttccat
    70381 tgttgctctt ggtttggcta tttgcttacc gatttacgat cattggtctg ggcgaatcgt
    70441 ttgcagtaaa tctgggaata gattaccaga agatgcagtt tttaggcatt ggcttagtat
    70501 cattggctag tgcagtcatg ttgatcatgg taggaagcat tccttttatc ggagtgatca
    70561 ttccgaatct tgtctctaga atatatggag atcaagtgca caaaacaatt ggcgtaactg
    70621 ctttagcagg tagtttgttc ttagtatttt gcgatcttgt cgctcgcgtg ttgatttttc
    70681 cttatgaaat accagtcagt gtgatcgttg gaatcatcgg tggggctatc ttcctttatc
    70741 ttctgataag gggacgacga tatgcttaaa aaaaagccat ctatttttat tggtatgctt
    70801 gttcttgttt tatttgttac aggaatgtac ttgacgatcc atacatatgg aaactggcat
    70861 tttgcatgtg cattgaggag taagaaaatt tttgcattta tccttgtctc gctagctgtc
    70921 agcagtgcca caatcagctt tcagacaatt acgcataacc agtttttgac tccttcagta
    70981 ttgggacttg agtcgttata tgtccttgtc caaacggtcc ttttcttctt tatcggagga
    71041 gtgacgatgc ttcagcagac aggtacagtt tttttcttat tgaacgttgg gctgatggtc
    71101 gggctgagtc tattgttatt tttctttctt ttgaaaaaaa tgagagcgaa tcttttttta
    71161 ttactgatgt cagggatgat tttaggtacg ctttttggta gtgtcagtac ctttttacaa
    71221 gtcatcatgg atccgaatga atatgatttg cttcaaggca gattatttgc aagctttggc
    71281 aatatccaga gtcagtatct tttgcctgct tctttgatca ttatcggctg ctggtacctg
    71341 ttatttcgat atcgacatgt gctagacgtt ttccatctcg gaaatgaaca agcagtaaac
    71401 ctcgggatag acacagatcg ttttgaattt ttgattttat gttgtgtcag tcttttgaca
    71461 gggacatcaa cggctcttgt gggtccagtt acttttttag ggtttattgt cgcaaatatc
    71521 agttatcgtg tcttttctac ttatcgtcat ggtcagctat ttatcggaag ctttctggta
    71581 gctatgctgt ttctgacagg aggacagctc gcagtagagc agattttcgg ctggaataca
    71641 acagtgagtg tcgtcgttga atttgtcgga ggaatttatt ttgtcacaaa attgattcgc
    71701 gaaaggaaga gtatcctatg attgatttac aaaaggtcaa taaactgtac catggaaaat
    71761 cagtggttaa agatgtacag ttaacgattc ctgaaaagaa attgactgct tttatcggtc
    71821 caaatggtgc tggaaagtca acggtgttgt cgatgatcag tcgtttgata ccaaaagata
    71881 caggtgaaat ctatttagac cataacgaag taaaggcttg gaaatccaat gaattagcca
    71941 aaaaattatc gatcctacga caatcgaatg aaataaatgt ccaaatcacc gtgaaagaat
    72001 tagtagaatt tggacgattt ccttatacga aaggaaaatt gacgacaaaa gacgaggaaa
    72061 tcgttcagga atcactggaa caccttgggt tagaagaaat agcggatcaa tcgattgaca
    72121 ctctttcagg cggtcaactc caacgtgcgt atattgcaat ggtgctagcg caagacacgg
    72181 attatatttt actggatgaa cctttgaaca atctagatat gaattttgcg gttcaaatca
    72241 tgcagatttt aaaaaattta gtacaagaaa tcgggaaaac aattgttatt gttcttcatg
    72301 atatcaactt tgctgcaagt tatgcagacg aaattgttgc aatgaaagat ggacagttat
    72361 ttacgcaagg aacgacccaa gaaatgataa aaaaagatgt attggatgaa ttatacgaaa
    72421 tggacatacg gatttgtgag attgaaggcc gcagattctg tctttatttc taaaactaac
    72481 attaggagag aagagatgaa aaaattagta gtaggtatct tgattctagc atcatttggt
    72541 ttagcagcat gtggaaatag caacaacacc agtcaggcag acacaaaaaa aagcagcaca
    72601 caaactgaaa ctacattgac gataacagat agtaatggag accaaatcga ggtgccaaat
    72661 aatccagaaa aagtcgtcgt attcgacaat ggttctttag atacgatgga tgctcttggt
    72721 gttggagata aggtagttgg agcagctaca agcagccttc ctgagtatct ttcatcctat
    72781 aaaaaagtag aatcagcagg tggaataaaa gaaccagact tagaaaaaat taatcagctt
    72841 cagccagatc taatcatcat ttctggccga caaagagatt ttcaaaaaga tctaagtcaa
    72901 attgctccga ccattttcct ttctttagat gcgaaaaatc catgggaatc tttccagcaa
    72961 aatgtcactg ctttagggga gatctttggt aagcaagaag aagctaaaac tcaattagag
    73021 gaattatcta gtgcaatcga tcagacgaaa aagaaagcag aagctactga caaaaaagca
    73081 ctagtcacac ttgtgaatga agggcaatta tcagcctacg gatctggttc tagattcggt
    73141 ttcatccatg atttatttgg ctttgaacaa gcagatgatc aaatcgaagc atccactcac
    73201 ggtcaaagtg tttcttatga atatgtgctg gaaaaaaatc cggatatctt atttgtagta
    73261 gacagaacaa aagctattgg tggagacgac agcaaagatg atatttctgc caatgaactg
    73321 gtagcacaaa cgaatgctgg taaaaatcag cagatcatct cccttgaacc agatgtctgg
    73381 tatttaagcg ggggcggttt agaatcaatg aaactgatga tcgaagatgt gaatcaagca
    73441 tttaaatagc ataaataaca gaggattaaa ctctcatact atgtaacaat aatgtttctt
    73501 acattcttaa atagcaagag cctatcctca aagaagttat caaaaaccat ccgtaaaatc
    73561 gtattgatga ttttacggat ggtttttatt tatttgagaa atcttttttc aacgtgaatt
    73621 cattatctac atcatacggg ttgattctag aatggggagt ggcaaaaaat agtgtgatcc
    73681 attttttcag catcaagatc gcctcctttg atttgaatca aaggtacaaa gcgaaactta
    73741 gataaaactt aaatttagat atttttattt tgtaccgatc tcttctttaa acgatgttcc
    73801 atctgctgct tctcggcaat aagtccacta gactagaaaa tatgagaagc tattttctgt
    73861 ccagcgttct tattactcaa agcaaatcgc agttgtcaca atctcttcta aacgatgttc
    73921 catctgctgc ttctcggcaa taagcccact agactagaaa atatgagaag ctattttctg
    73981 tccagcgttc ttattactca aagcaaatcg cagttgtcac aatctcttct aaacaatgtt
    74041 caatcagctg accttcggta ttagctcaaa gcactgattt cacaacctct atttaggcat
    74101 gtgtctcagc aagcggttga tagttgatga tctgcatttt tcgataaaaa tcggcgggaa
    74161 gcttactcca ccgttttaat aattgataga aataactctc ttctgctttg attttatact
    74221 cgcttaatat caatccaaaa ctattcgttt tttttgaagc taatttttta taaatatcca
    74281 atgctttggt tttatcttca ttgacaaaga gtgtttttac ttcaatataa gaaccctcga
    74341 tattttgtgt ttcttcgata aaatagatgt tttttatata ttccttcata gtgattcctc
    74401 caaagaagtc ttttatttga taagtttact ctaccgaaga gttgttaata atccgtgaac
    74461 aaaaagtaat tctttttcca atagttgtta aaggtttttt attttttata gtattttttg
    74521 ttatttaaga aaggaataag gttaaacaaa taacaggttg ctttttgggt ctttttccgt
    74581 tcaagaaact gaacgaagaa aagggaaagt tgtctctttt gtgataagag aaatcataat
    74641 aaacgaatga cttactttcc aataaattga gaacagtcag aaccagacaa attagttgca
    74701 tctgatgaat aaagtgatta ttctatgaca tgaggtgata cagatgaaat tagaagtgac
    74761 aaaagaagca caagaagtat tgaagaataa attagaagca gacgatcaac ttttattaga
    74821 tatcgaaaac ggtgacggtc catttgcaga aagccaagtc agttgccaat tggatacggc
    74881 atttcgattg atcattgtca aaaaagatac acaaacagat ctaagtcttt attctgtagt
    74941 ggctgataca ccagttggac caatcaaaat caaagacagt gcaatacttt acatggatga
    75001 tccatccaca cttgctttag aaccaactta taatagttta caattaaaag gaccaagcgg
    75061 cttgagaaaa ggcaacttgc aagttgttcg aaaagactag agggataaaa tgggaaaatt
    75121 ggcgatcatc agcgacctac atgtggacat caataaattc ggcgaatcag agctgatgca
    75181 gctttggcaa gttttgcaaa agcacaagat cactcggctt catctagccg gagatacggc
    75241 taataaagta gaccgttgcc tagctgttgt cgaatttttc gtcaataaag gattatctac
    75301 gacatttcat ttcggcaatc acgagttggc agatgtgccc aatgaacaga tgatggacca
    75361 ttttccagac ccacattttt taaatgaacg gtatattgct ttaaatgagc agaccgttct
    75421 tttagggatg aatggctggt acgactatca gttttccgaa ttgaaagatt acgaggcaat
    75481 cgtacgaatg aagcgtttgt attggtatga tcggttcatc cagcgtggga aaacagatct
    75541 cgaggtcaat gcagaaatgc ttgcagctgc aaaaaatttg ctagaccagc tggaagcaaa
    75601 aaaacttgag gtgattttat ccactcattt cgttcctaaa cgggcattta tcatgtatca
    75661 atctgctcct tatgagcgtt ggaacaaatt aaatgcattt ttaggatcag aatcattcgg
    75721 agaattactt gaccgttatt caaatatcaa acaagtagtt tttggccata cgcatcgtcg
    75781 ctttgaagat aaatccatcg gtcacacgat ttacagctgc agaccttttg gttattatta
    75841 tgaatggcag ctgacccgag attttgtctt gaaagaacag ttgctagaca gctatgatcc
    75901 tatgaaatta cgtgtcctct tgcgtgccca tcacccagct tttcaggcct atcaaacaca
    75961 acatttgcaa gaggaatttg aacaagcgat gacaatcgtt ccgtattgag acagcattag
    76021 taatgtgtaa aagaaaatac cttgtaaaac ataaggataa gtaagagcag tagatccatt
    76081 tatcgtggat atgctgcttt ttttgcggaa aataatcagc gaatgtttat ttgatcggat
    76141 gatttgtaac tcgcagagta ctagatgcaa gcgtgtattc tttttttgaa cgataatcac
    76201 aaaaaaaaat a
//
LOCUS       DACDAF010000002        68282 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.002, whole genome shotgun sequence.
ACCESSION   DACDAF010000002 DACDAF010000000
VERSION     DACDAF010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68282)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68282)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68282
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.002"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            126..725
                     /locus_tag="IVZ69_000087"
     CDS             126..725
                     /locus_tag="IVZ69_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP8182208.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            complement(794..2095)
                     /locus_tag="IVZ69_000088"
     CDS             complement(794..2095)
                     /locus_tag="IVZ69_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP8182209.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            2675..3931
                     /locus_tag="IVZ69_000089"
     CDS             2675..3931
                     /locus_tag="IVZ69_000089"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HAP8182210.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     gene            4222..6099
                     /gene="tdc"
                     /locus_tag="IVZ69_000090"
     CDS             4222..6099
                     /gene="tdc"
                     /locus_tag="IVZ69_000090"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP8182211.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            6342..7763
                     /locus_tag="IVZ69_000091"
     CDS             6342..7763
                     /locus_tag="IVZ69_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8182212.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            7872..9239
                     /gene="nhaC"
                     /locus_tag="IVZ69_000092"
     CDS             7872..9239
                     /gene="nhaC"
                     /locus_tag="IVZ69_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAP8182213.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
     gene            complement(9520..10539)
                     /locus_tag="IVZ69_000093"
     CDS             complement(9520..10539)
                     /locus_tag="IVZ69_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8182214.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(10561..11568)
                     /locus_tag="IVZ69_000094"
     CDS             complement(10561..11568)
                     /locus_tag="IVZ69_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP8182215.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            complement(11561..12226)
                     /gene="pgmB"
                     /locus_tag="IVZ69_000095"
     CDS             complement(11561..12226)
                     /gene="pgmB"
                     /locus_tag="IVZ69_000095"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP8182216.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            complement(12219..14513)
                     /locus_tag="IVZ69_000096"
     CDS             complement(12219..14513)
                     /locus_tag="IVZ69_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP8182217.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            14773..16938
                     /locus_tag="IVZ69_000097"
     CDS             14773..16938
                     /locus_tag="IVZ69_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8182218.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            17242..18075
                     /locus_tag="IVZ69_000098"
     CDS             17242..18075
                     /locus_tag="IVZ69_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HAP8182219.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(18177..19877)
                     /locus_tag="IVZ69_000099"
     CDS             complement(18177..19877)
                     /locus_tag="IVZ69_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182220.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLHA
                     "
     gene            20384..21544
                     /locus_tag="IVZ69_000100"
     CDS             20384..21544
                     /locus_tag="IVZ69_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP8182221.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            21560..22003
                     /locus_tag="IVZ69_000101"
     CDS             21560..22003
                     /locus_tag="IVZ69_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8182222.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(22486..23016)
                     /locus_tag="IVZ69_000102"
     CDS             complement(22486..23016)
                     /locus_tag="IVZ69_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HAP8182223.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSRKYFDENYKRVK"
     gene            23121..23672
                     /locus_tag="IVZ69_000103"
     CDS             23121..23672
                     /locus_tag="IVZ69_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP8182224.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(23825..24298)
                     /locus_tag="IVZ69_000104"
     CDS             complement(23825..24298)
                     /locus_tag="IVZ69_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP8182225.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            24436..25908
                     /locus_tag="IVZ69_000105"
     CDS             24436..25908
                     /locus_tag="IVZ69_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP8182226.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            25905..26615
                     /locus_tag="IVZ69_000106"
     CDS             25905..26615
                     /locus_tag="IVZ69_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HAP8182227.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            26967..27251
                     /locus_tag="IVZ69_000107"
     CDS             26967..27251
                     /locus_tag="IVZ69_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HAP8182228.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(27532..27951)
                     /locus_tag="IVZ69_000108"
     CDS             complement(27532..27951)
                     /locus_tag="IVZ69_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HAP8182229.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(27953..28537)
                     /locus_tag="IVZ69_000109"
     CDS             complement(27953..28537)
                     /locus_tag="IVZ69_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HAP8182230.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(28584..30059)
                     /locus_tag="IVZ69_000110"
     CDS             complement(28584..30059)
                     /locus_tag="IVZ69_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HAP8182231.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            30240..30551
                     /locus_tag="IVZ69_000111"
     CDS             30240..30551
                     /locus_tag="IVZ69_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182232.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(30667..33003)
                     /locus_tag="IVZ69_000112"
     CDS             complement(30667..33003)
                     /locus_tag="IVZ69_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8182233.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            33145..33813
                     /locus_tag="IVZ69_000113"
     CDS             33145..33813
                     /locus_tag="IVZ69_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8182234.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            33816..34859
                     /locus_tag="IVZ69_000114"
     CDS             33816..34859
                     /locus_tag="IVZ69_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP8182235.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(35096..35977)
                     /locus_tag="IVZ69_000115"
     CDS             complement(35096..35977)
                     /locus_tag="IVZ69_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP8182236.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            36136..36864
                     /locus_tag="IVZ69_000116"
     CDS             36136..36864
                     /locus_tag="IVZ69_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HAP8182237.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            37020..37337
                     /locus_tag="IVZ69_000117"
     CDS             37020..37337
                     /locus_tag="IVZ69_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP8182238.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            37330..37938
                     /locus_tag="IVZ69_000118"
     CDS             37330..37938
                     /locus_tag="IVZ69_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HAP8182239.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            37954..38784
                     /locus_tag="IVZ69_000119"
     CDS             37954..38784
                     /locus_tag="IVZ69_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HAP8182240.1"
                     /translation="MRLKHFLITGIGLMLTGGLLAGATYTLGAQKSLTWDNGPRLIDM
                     VTETKKIKDANKIVIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKK
                     STGAIISLEDTSAQITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSF
                     NEFTGGTITAKDELGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSL
                     HEMENSGYTIQTSGESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD
                     "
     gene            38922..39410
                     /locus_tag="IVZ69_000120"
     CDS             38922..39410
                     /locus_tag="IVZ69_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HAP8182241.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            39461..40333
                     /locus_tag="IVZ69_000121"
     CDS             39461..40333
                     /locus_tag="IVZ69_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HAP8182242.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            40509..40871
                     /locus_tag="IVZ69_000122"
     CDS             40509..40871
                     /locus_tag="IVZ69_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP8182243.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            40880..41632
                     /locus_tag="IVZ69_000123"
     CDS             40880..41632
                     /locus_tag="IVZ69_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182244.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            41646..43448
                     /locus_tag="IVZ69_000124"
     CDS             41646..43448
                     /locus_tag="IVZ69_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182245.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            43725..44765
                     /locus_tag="IVZ69_000125"
     CDS             43725..44765
                     /locus_tag="IVZ69_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP8182246.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(44817..46961)
                     /locus_tag="IVZ69_000126"
     CDS             complement(44817..46961)
                     /locus_tag="IVZ69_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP8182247.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(47318..48691)
                     /locus_tag="IVZ69_000127"
     CDS             complement(47318..48691)
                     /locus_tag="IVZ69_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8182248.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(48691..49086)
                     /gene="rbsD"
                     /locus_tag="IVZ69_000128"
     CDS             complement(48691..49086)
                     /gene="rbsD"
                     /locus_tag="IVZ69_000128"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002829567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HAP8182249.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(49114..50031)
                     /gene="rbsK"
                     /locus_tag="IVZ69_000129"
     CDS             complement(49114..50031)
                     /gene="rbsK"
                     /locus_tag="IVZ69_000129"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HAP8182250.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(50139..51152)
                     /locus_tag="IVZ69_000130"
     CDS             complement(50139..51152)
                     /locus_tag="IVZ69_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8182251.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(51233..51832)
                     /locus_tag="IVZ69_000131"
     CDS             complement(51233..51832)
                     /locus_tag="IVZ69_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP8182252.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            52018..52719
                     /locus_tag="IVZ69_000132"
     CDS             52018..52719
                     /locus_tag="IVZ69_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182253.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            52729..55440
                     /locus_tag="IVZ69_000133"
     CDS             52729..55440
                     /locus_tag="IVZ69_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP8182254.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            55891..57519
                     /gene="treC"
                     /locus_tag="IVZ69_000134"
     CDS             55891..57519
                     /gene="treC"
                     /locus_tag="IVZ69_000134"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HAP8182255.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(57579..58760)
                     /locus_tag="IVZ69_000135"
     CDS             complement(57579..58760)
                     /locus_tag="IVZ69_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP8182256.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            59012..60535
                     /locus_tag="IVZ69_000136"
     CDS             59012..60535
                     /locus_tag="IVZ69_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HAP8182257.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(60604..61332)
                     /locus_tag="IVZ69_000137"
     CDS             complement(60604..61332)
                     /locus_tag="IVZ69_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8182258.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(61345..62625)
                     /locus_tag="IVZ69_000138"
     CDS             complement(61345..62625)
                     /locus_tag="IVZ69_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP8182259.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(62766..63368)
                     /locus_tag="IVZ69_000139"
     CDS             complement(62766..63368)
                     /locus_tag="IVZ69_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory regulator AgrB"
                     /protein_id="HAP8182260.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            63613..63819
                     /locus_tag="IVZ69_000140"
     CDS             63613..63819
                     /locus_tag="IVZ69_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182261.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            64131..64850
                     /locus_tag="IVZ69_000141"
     CDS             64131..64850
                     /locus_tag="IVZ69_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP8182262.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(64931..65614)
                     /locus_tag="IVZ69_000142"
     CDS             complement(64931..65614)
                     /locus_tag="IVZ69_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HAP8182263.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            65832..68018
                     /locus_tag="IVZ69_000143"
     CDS             65832..68018
                     /locus_tag="IVZ69_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP8182264.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        21818 a        12144 c        13833 g        20487 t
ORIGIN      
        1 gtcaatgaat tcataaacaa ggaattgcta gcttgatact ttctcaatag atagttataa
       61 taaacctcag aataaatttg aactatatat attataaaag tttaaaatta cgggaggctc
      121 tacaaatgaa cggttttgaa aagagagcac aagagaaaaa gaaagagatt ttacaagcag
      181 cttttgactt gatgaacaca gacataggaa ccgctggagt gacaatggat aaggtagctg
      241 agaacgctca ggtaagtaaa gcgacgattt ttaaatattt tggcagcaag gaagggctga
      301 tttatgaagt attttttgca tttatgaatg atttagggca agaagcgaaa gcgttgattg
      361 cggaaaatct tccatttgaa gaaacactga ttgccatgag tgaaaacaaa atccgttatc
      421 tcaatcgagt gaacaaacaa ttttatatcg atttgatgac atactataca aaaaaagaaa
      481 aaaaagaatt ttctgacgcg atggatgcgt atacgcaaga aagtttcagt atcatgcttg
      541 atcttttcca tcgagggcgg aaagaaggaa aagtggattt gaaatattcg gatgagttct
      601 tgatcctcta ttttcaagca atggtagaag gaatttctaa gccggagata tacgcaaaac
      661 tgcttccata tacagcagaa tggacagaag tcctgatcaa gggaatcgca ccgaagaaga
      721 aataaagcat aaaaaagccg aaactgacga taaaatgtca gttcggcttt tttggttcat
      781 aaatgacgta aaatcaagca gattcgcgtg cttctttgtc atagacatca tggacattga
      841 tgaatggatc aagaatagga ttttttccgt ctaaatcaga ttgaaaacga atgccatcga
      901 tattgatccg agcatttcga tagaaatccg tacctaattg tccccaagct ggtgtagaag
      961 catcgacatt acagaaaata tcgaaacctt gactcttcaa gtaagcaaat ttttgatttt
     1021 ctgctgaata aggctgccag tcgctgatgt ctgcaccaaa tggataaatc agaatatttg
     1081 tttttcctag gataggtgca acttcttgct gccacaattc attgtctttt tttacatctt
     1141 ctagtgaagc ttgagtcata ttcaagtgac cccatgtatg ggaagcaaag ctccagccgt
     1201 ctttcttcaa ctgttccgcc acttttttag cttctttaat ctcttttttt gttttttcat
     1261 tgtctccata ttgagatttt gatgttcgat aacctaaaac tccgttgtaa cctgtcaggg
     1321 ccaaggtacc ttttgcgcct cgataagaaa aatcaggatg tttcttgaca aaggcatcga
     1381 tcagaggaac catgtcaaag tcaccgattt cttctttatc tttctcttta tagacatttt
     1441 tgatttcatt gttatttgat acgaccaatc ggctaggaaa accggaatta tccatatatt
     1501 cataatagct gacatcatct tgtgaaagaa ccaatggttt ttttccttca ggtagcgcaa
     1561 gcccgttaaa ggaaagattt ccttgttcgt ctttttggat caaatcattc aaattaacta
     1621 aaacaaaatc attttgataa agttgttcga tcgaacggtt gaattcttca acagtcacca
     1681 tataatcttt gtatccttgt gcctgttgag agtggaaggc tttttgcggg tccacgatca
     1741 agctgtggaa aaagacatga gagatctgag taggatcaga ccagtcgatc agttgttctt
     1801 tctccttttt tagtgtttga agaagctgtt gtgtttcagt agatccgttc ttactatctt
     1861 tttccaataa cgcaatcgct tggtcataat cgtagctttg agccagattt tttgcttgag
     1921 taactagttg ttgcttatca tctgtcggtt cttttgcttt ttctgttatt tttttttcag
     1981 gaatgattgg ttcttttttt gtagatgatc ggatgacaaa aaacaaactt agaattaaaa
     2041 taacgatagt taaagcagaa gtggctccta aaataatttt ttgctttttt tccatatacc
     2101 tcgtcccttg ctttttcatt tttttacttg tcccattcct tattgtaacg aagaaagaat
     2161 aagaggcaaa gtaaagtgac ttctcgataa attgcagaaa aaatacagaa aaagttattt
     2221 cttttaacaa taattgaaaa taaaatgttc ggaattagag cggattcaaa aaagaaaaaa
     2281 tgaggaattt aaaaaaaata tcctttttct gttgacaaag aaaaagttgc gctctatgat
     2341 agacacatat taataataac aagacgaaga tcgaaacgaa gtagttgtta aagccaatgt
     2401 ttcagaaagc tggtggtcgc tgcaaaccag tacatgcttt aaagcgaatt acatttcagg
     2461 agtctttggc agtgattgcc acgcgacagc gttaaatgtt cgagaggtat gttggatatc
     2521 tagacataca aattgggtgg taccgcgaga tttcgtccct tggcttatat gccaagggac
     2581 tttttttatt tcctatccta tcctgaagaa ataattaatt acacatgcta gcaggttcct
     2641 gctttcataa aaaaactaca cggaggtcag taaaatgaat attattgatg aattaacttg
     2701 gcgcgacgcc attaatcagc aaacaaacga agaaagactt cgcgagctcg ttgaagaaaa
     2761 gagcatttca ctttattgcg gcgttgatcc aactggtgat tcgatgcata tcggacattt
     2821 gattccattt atgatgatga aaagattcca attggcaggc catcatccat atattctgat
     2881 tggcggcgga acaggaacga tcggcgaccc aagcggccgc aaaacagaac gtgtgttgca
     2941 aacgatggaa caagtgcaac ataacgtgga cgcactttcc aatcaaatga gaaaattgtt
     3001 tggtaaagat gcaaatatca catttgtgaa caactacgac tggttgtcaa aaatctcttt
     3061 acttgaattt ttgagagact acggtaaaaa cttcaacatc aacacgatgt tagcaaaaga
     3121 tatcgttgcc agccgtttgg aagtaggaat ctcatttaca gagtttactt accaaatcct
     3181 gcaatctatc gactttttgc atctgcataa aacatacgat gtgcaattgc aaatcggtgg
     3241 agcagaccaa tggggaaata tcacagctgg attagaccta atccgaaaat tagaaggacc
     3301 agaagcagaa gcgttcggtt taacgatccc attgatgctg aaggctgacg gaacgaaatt
     3361 cggaaaaact gcaggcggtg ccgtttggct tgatccgaag aaaacttcac catttgagtt
     3421 ctaccaattc tggttgaatc aagatgatcg cgatgtagtg aaatacttga aattctttac
     3481 tttcttgtct caagaagaaa tcgaagactt agcgaaaaaa gtagagacag aacctgagaa
     3541 acgtgaagca caacgccgtt tggcagaaga agttacaaga tttgtgcata gtgaagaaga
     3601 cttgaaagaa gcgcaaaaaa taacgcaagc attgttctct ggaaatatta aagaactaaa
     3661 tgcggaagaa atcgcgcaag gattcggtaa aatgccgaac gttgaaattt caagcacacc
     3721 tgaaaatatc gtggaactgc ttgtttccac aaaaattgaa ccatctaaac gtcaagcacg
     3781 tgaagatgtt tcaaacggag ctataagtat taacggtgac cgcgttaccg atttaaattt
     3841 tgtcataaat ccatccgatg aattcgatgg taagtttgtg gttattcgaa aaggtaagaa
     3901 aaattacttt ttggccaaag taattgatta gaatttagta agtttttacc ttgaaaaagg
     3961 gaaatactat tacaacattc caattttgaa acccatccta aaatagaacg ctggttgtcg
     4021 ttaatacaat ctttgcgagg gagtttacat ttgtaaattc cctcgttttt tttaattatt
     4081 tcaaaagtgt gaacaattcg gataattgat acatattaaa atatgattaa aaatcaggcc
     4141 aaaacttagt ttacagaata gaagaacagg tgtaatgtag ggctcgacaa aatttaaata
     4201 tttttttagg agggtttcac tatgagtgaa tcattgtcga aagatctaaa cctaaatgcc
     4261 ctattcattg gggacaaagc tgagaacggc caaatctata aagctttgtt gaatgaattg
     4321 gtggatgaac atttaggctg gcgtcaaaac tacatgcctc aagacatgcc tattattacg
     4381 ccagaagaaa aaagcagtgc tagttttgaa cacactgtga ataaaacaaa ggatgttcta
     4441 tcagaaattt cagcgcggat gcgtacccat tccgttcctt ggcataatgc cggacgttac
     4501 tggggtcata tgaactctga aacattgatg ccatctttac tagcgtacaa ttttgctatg
     4561 ctatggaatg gtaataacgt tgcctatgaa tcttctcctg caacaagcca aatggaagaa
     4621 gaagtaggaa tggaatttgc aaaattaatg agctataaag atggctgggg ccacatcgtt
     4681 gctgatggtt ctttagcaaa cttagaagga ctttggtatg cccgcaacat caaatcattg
     4741 ccgcttgcaa tgaaagaagt gacacctgaa ctagttgctg gaaaaagcga ttgggaatta
     4801 atgaacttgt caacagaaga aatcatgaat ctgttagaca gcgtcccaga aaaaatcgac
     4861 gaaatcaaag ctcactcagc acgtagcgga aaacatttag aaaaattagg aaaatggttg
     4921 gttccacaaa ctaaacacta ttcatggcta aaagctgccg acatcatcgg tatcggttta
     4981 gaccaagtga ttccagtgcc agttgaccac aactatcgca tggacatcaa cgaacttgaa
     5041 aaaatcgttc gtggtctagc agctgaaaaa acaccaatcc taggtgtagt cggtgttgta
     5101 ggatcaacag aagaaggagc aatcgacggt atcgataaaa tcgttgcatt gcgtcgcgta
     5161 ttagaaaaag acggtattta cttctactta cacgtagatg ctgcttatgg cggatacggc
     5221 cgtgcgattt tcttagacga agacaacaac ttcattccat ttgaagattt aaaagatgtt
     5281 cattacaaat acaatgtctt tacagaaaac aaagattata tcttagaaga agtacacagt
     5341 gcatataaag caatcgaaga agcagaatct gtaacgattg acccacataa aatgggctat
     5401 gttccatatt ctgccggtgg tatcgtcatc aaagatatcc gcatgagaga cgttatctct
     5461 tactttgcga catatgtatt tgaaaaaggc gcagatatcc cagcattact tggggcttat
     5521 atcttggaag gttcaaaagc aggggcaaca gcagccagcg tttgggcagc acaccatgtc
     5581 ttacctttga atgtcacagg atatggtaaa ttaatgggtg catcaatcga aggtgcacat
     5641 cgtttctaca acttcttgaa tgacttgtca tttaaagtag gagacaaaga aatcgaagtt
     5701 catccattaa cttatccaga tttcaatatg gtagactatg tattcaaaga aaaaggcaac
     5761 gatgacttag ttgcaatgaa taaattgaac catgacgtat atgattattc ttcatacgtg
     5821 aaaggaagca tttacggtaa tgagttctta acttcacata ctgactttgc tatcccagac
     5881 tatggcaaca gcccattaca atttgtgaac caactaggat tctcagatga agaatggaac
     5941 cgtgccggaa aagtaactgt attgcgtgcc agcgtaatga caccatacat gaacaaagaa
     6001 gaacactttg aagaatatgc tgaaaaaatc aaagcagctc ttcaagaaaa attggaaaaa
     6061 atctacgcag accaattatt ggcaagcgaa gcaaaataag caaggtaatc atgttagaaa
     6121 acagcttgaa tactaactgt ttctgacgca tgtttggatc tgaagagcaa ggggagacct
     6181 aagctcttcg atccctttgt tttgaggttg tctttgaaga aacccttcaa gcaataaact
     6241 caaagaatcc cctcaaatat tcgctgaatt gtttcgttta ttgctgaaac tacttcaaag
     6301 acaccgttat tttatccaaa aaatcaagga gagtgtcaac ggtgagtaaa tctgaagtaa
     6361 gtaaaatggg tcttgggacc tttatcggtc tgacaatggc actgtgtgca acggttcgga
     6421 gtattcctac gttagccgca gtcggttgga cattgatttt ttattcaatt tttgcagttt
     6481 tgttttttgc cggtccgata tcaatggttt ccggtgagct ttccacgatg cttcctcaag
     6541 aaggcggtcc tcagttatgg gtaaaaacag cactgggcag caaatgggga tttgtcgttg
     6601 catggctatt atgggtgcaa atgttcccag gtatggtaat ggtcgcttct actttaggac
     6661 cattgttagg aaacacattt ggtaatgtag aacttggcaa taatcactgg ttcgttttag
     6721 gttgtatttt agttatctac tggatcatca cgatcttgaa cttgaaattc gatatggcaa
     6781 aagtcggcgg gaacatcggt gtatggctag gggtatatat cccagtagtc atcatgttcg
     6841 ttttaggtgt tttggcagcc ttcaaagtcg gactagtctc aaacggctat ctaggtgact
     6901 tttcatggtc aaaagctttc cctgacttgg aacatattga ttcattgaaa tacttagctg
     6961 gtatcacatt tatttttgtt gggatcgaaa tgagttctgt ttacatgcct cgtttgaaag
     7021 acgcaacaaa aaattataca aaaggcgtat ttatcgcttt gatcggatta gttttattga
     7081 atgtcatcaa tgcgatgctt gtagcaaatg tcgtaccaga tggaaaaatg gaattagcaa
     7141 atatcacgca gcctatcttg attgactgtc aaatcctagg cttaccagaa gtgatcggaa
     7201 atatcttcag cttcatggta tttattggtg tgcttttaca attatcagct tgggttactg
     7261 gaccatcaaa aacaatcatc caagtagctc gtgaaggatt ccttccacca aaattcggat
     7321 tccataaaga aaacaaatac ggcgtatcta gaaatgtcgt tctaacacaa tcaatcgtta
     7381 tttcattatt tgctttgctt tatggtgtaa tggatgacgt aagtgctgta ttcttgacac
     7441 ttacaaatgc tacaactgtt atttattgta tcgtgtacat tttgattgct gtttcattgc
     7501 ttaaaatgcg taagaaacat ccagaattcg aacgtcctta ccgaattggt aaaaacggaa
     7561 acggattagc ttgggtagtc agctgcatgc tgatcttctc tatcatcgtt gtcgtatttg
     7621 ctacattagg tacagcgaca ttgagtgatg cattattagt agcagctatc acagtggtca
     7681 tgttcgttat tccattgatc atcaatcact tcaagaaaga ttcttggggg attgaggtag
     7741 aaaaaagttt agaagaaaaa taaaaaaata agtctttcag ccgacgtttt gtcgctgatt
     7801 tagtaggagg tcctgccaag tgaatagttt tttcatggca gggccttttc atttgaaata
     7861 ggagatcgac gatgaataaa aatatttctt taaaagaaag tatcgctgta ttgatcgtgt
     7921 tgttggcact cctaggagta ctgatcatcg gattccagct ctcgccacat atcccgatcc
     7981 ttgcagcttt catgtgtttg ttgttttatg gcagatttaa aaagttcaca tgggatgaga
     8041 tccatgacgg gatcatcaaa ggaatcactc cagggatcat tccaatcctg atttttcttt
     8101 tgattggtgt cttagttgct tcatggattt tatctggaac catccctacg attatggttt
     8161 atggatttaa acttgtttct gtgcgtttct ttttaccgac agcatttctt gtttgtgcaa
     8221 ttgtcggagt gactgtcggc agttcattta caacgatttc gacgattgga attgcttttt
     8281 tggggatcgg tcatttactt ggattcaatg atgcaatgac tacaggcgca gtcgtttccg
     8341 gtgccttttt agggaataac tgctcgcctt tatcagatac gaccaacttg gcagcgggta
     8401 ttggaggagt taatctattc gaacatatcg ctggtatgcg ttatacggat ttcccagcat
     8461 tcgtcctttc gttgattttt tatacgatat taggacataa cagtcattca gccgatctag
     8521 ctagtatcaa tgaaatgatc caaaacatga aagcgagctt ttggatctct ccttggacat
     8581 tgattccact agttatttta tttggggggg caatcaaaaa aattccggct atccctacat
     8641 tactagcggg atcgacagct gctctcgttc tttcttttat ccatgagaaa agtttgacgg
     8701 tcggaaaagc agcagacatc ttgatgaatg gttatgtcgc aaatacacct gatccaaagc
     8761 tagatgaact gctttctcga ggcgggatca tgagtatgtt aggttctgct agtttgattt
     8821 tacttgcatt ggcattaggt gggttactga tcaaatatct gatcgttgat accatcgttc
     8881 aagaattaaa agaaaagatg gaccgacctt ctcgtttagt cgggtttact gccttgagct
     8941 gtatcggaat caatctgatc gttggagaac agtatctgtc catcattctt ccaggagaaa
     9001 cattcaagcg ttcttttgat gacgttggct tatcaaaaac ctatttgaca cgaacactag
     9061 cggattcagg tgcgaccgtc aattctctcg taccgtgggg agtcagcggc acattcatta
     9121 tgggaacgat gaaagttagc gcgttgcatt acttgccatt cgcctttttc tcgattcttg
     9181 cacctgtctt tacaatatta ggcggttttt tattgaatcg tcgacgtgta aaaaattgaa
     9241 ggaaggaaaa aagaggctgg gacagaagcg tttaactcca agaaataaga agaaactcaa
     9301 gaaaattgct ttttaaattt ttgtgaattt cagcttattt ccgaaggagt tgcttctgct
     9361 tccgccgttt atacgtgttt agagcgtgag acaaaagtgt tctttacttt tgtcccacgc
     9421 tcttttttac agataaacaa tgtgttagaa gtagtatctt cttttacata aaaagctgac
     9481 cataggataa atggtcagcg tatttagtga gtcagctatt tagtatgggt tttctaaagg
     9541 aacgactgtc tctcttttga tcaagcgatg agggatgacc aaacgtacgc cactgctcaa
     9601 ttcttcatgg atcaattcgc gcagcttttg catagcgaca cgtcctaatt cggagatatc
     9661 gatatcgata cttgtaaggt aagggtgtgt taatgttgag aagatcgagt tgttgaagct
     9721 aatgacggag agtgtctctg gaatgacata gccatacatt tgcgccaact gcatcgtgcg
     9781 aagggcgaag atatcgtcaa tgaccaccaa tgctgtggct tcgttttctt tcaacgtttt
     9841 ctcaaaggac agataatcct ccggatgctc tagtactaca ctggataacg caggaagacc
     9901 agccatcatc attgcttttt gataaccgaa atatcgttcg aaatacaaac tttcatgagt
     9961 cgtgtttgtc acaaacagga tattcttatg tccattctgg atcaaaaatt ctgttgcttg
    10021 tttacctaga agctggttat cattatctac ataaacgatt tcgttctcat gatgataagg
    10081 ctgtccgatc aaagtgaaag ggatgtggtt ttggtataaa taatcaatga cagtatcttg
    10141 actatctgaa tacactagaa taaaaccatc tacttgtttt tgtaaatgca tacgctggac
    10201 gttctctaac agcaattcaa aatttttagc agtagcgatt gctgtagtca tatcataatt
    10261 ccgcgcttct tcgttgattg cttccatgat ctcaagataa aatgggttac cgatccgctc
    10321 ttttgaatca agagggggta agattacgcc gatggcactg gaaatgcgtt ttcctagatt
    10381 gcgggcagtc atgttaggaa cataacctag ttcatccata atttttcgga ctttcttctt
    10441 tgttgtctcg gaaatactag gatgatcgtt gatgacacga gagacggtcg aggtggcaac
    10501 accggctttt ttcgccacat cttttacggt aatagccatg ataaaaacac ctttctcttg
    10561 ttattgtgca gagaaccgat aaatcgtctg actgatccgt tcttgaccag gatggaggtt
    10621 gatcgatcca aatttgggga aatgaacgat atcagggatt tcttgcggtt cgattgctaa
    10681 tccgtagttt gaatgcatct gttttccatt gacagagaaa tcagcttcga atccagtcgt
    10741 agaaaataat accatacttt tattagaagt tgctatagtc atttggcgac cagaatgctt
    10801 ctcgaataat tgtaaggaag ttttggaaag cctaggatga tgcaaaagaa atacatcatc
    10861 tagtccatct ggataacatg caaggatctc ttgcagtgtt ggggattttc taaagtcgat
    10921 tggcagtttt tctttttttg tccaatttcc agtaggcagt ttttcttgat ctaattcaag
    10981 cacaccatct aaaaagaccg ttaactgatg ttcatagatg tctcttgttc catttcctga
    11041 aaggttgaag taggcatggt tggtcggatt gcagatggtt tcaacaaggc tactagcaga
    11101 ggttgtcatc tctaattcgt tttttgttaa acggtaagtg atcgtagcag tgattggtcc
    11161 tggataggta gaaaattcat cttttaagta aaagaccaca cctattgatg atggagtttt
    11221 gaaaacttct acttcccaaa attggaaaga ccagcctttc gtgccaccgt ggatatggtg
    11281 tgatccgcag tttttctcca atctatgctc accccaagaa gcatcccgga tccttccggc
    11341 tacaggtccg acagttgctc caaaaaagct tttgtctgtt agaacatctt cgaaacgatc
    11401 gtaagacaat aaaacatttt ctgattttcc ttctttgtct ggtgcgaaga tttggtgcag
    11461 gcgggcaccg taattgagaa gaacgacttc taagtagtcg ttcttcaatg tgattttctt
    11521 tatttcagtc tctggaactg gtacgacgga gatctctgga ttatccatgg tcatgccact
    11581 tttctttcaa gtaatcgatc gtaagaaaag tcgtatcagg gacaagcggg atctcctctc
    11641 caaggtcttc agcacgtccc acgccaattg gttgagcgcc acttgagagg atggcttgga
    11701 taccggcttg cgcgtcttcg atcccgatac attcttctgc ttttagtccg acagcttttg
    11761 ctgcaaggag gaagatatct ggcgcaggtt ttccgtttgt tgcttctgcc gggtcggcaa
    11821 tagcatcaaa gtaaggtgta agacccattt tttcaagtag gaatggcccg tttttacttg
    11881 cagaagcaag agcaatcttg attttttctt cttttaaaga atccagtaaa ggcacgaccc
    11941 cggggaagac atcttttggt tcgatcgtct ggatcatctc taaataataa tcgttttttc
    12001 ttttcgctaa ttctgcaaat tcttcctttg aaaaagagtg ttcttttccg ccataagcta
    12061 aaagcaaaga gagtgagtct tctcggctga cgccttttag ctgttcgttg aatgtgtggt
    12121 cgatcgtaat gccgatttcc tgaccaagct ttcgccaagc acgataatgg aattcagcag
    12181 tatcggtaat gacaccgtct aaatcaaaca ataccccttt aaacatttgc ttcctccttt
    12241 cttagcgtta tttctagacg atccgctaaa gaataagact gttcatagac gtaaatttct
    12301 agaggagaac cttctaataa ctcgaaagta acttgttcat ctgtgactga gatgaacaat
    12361 aaacgtccgc gataattgat atggaaagaa taagctttcc aagtttttgg cagaaatggt
    12421 gcgaatctca actgatcatg ggcagttttc atttgagcaa atccttggac aatcgacaac
    12481 cagctaccag tcatggaagt gatgtgcaag ccgtcttctg tgtcgttatt gtaattatcc
    12541 aaatccaagc gagctgttcg ctggtacatt tctacagctt tgctttccat tcctaattct
    12601 gctgctaaaa tcgaatggat acttggcgaa agggaagact catggacagt cattggttca
    12661 tagaaatcaa agtttttttg cttttcttct tttgtaaaag tatcattgaa gaaataaatc
    12721 ccctgtagta catctgcctg cttgatgaag caagatctaa ggattttgtc ccaagaccaa
    12781 tgctgattca gaggaagatc gcttgtggga atatcggata caggcatgag atctttatct
    12841 aagaatgtgt catgctggac aaagattcct aattcttcgt caactgggaa gtacatgttc
    12901 tctgcgatat ctttccattt ggctagttct tcttcgctga tagtgatagc agcttctttt
    12961 tgataagtta aataattttc tcgcgtgtaa cgcaagaccc aagctgcgat cgtatttgta
    13021 taccaattgt tattgatatt gttctcatat tcgtttgggc cggtcacacc gtggatcatg
    13081 tatttatttg ctcgttttga aaaatggaca cggtctgccc agaagcgtgc gatttctgct
    13141 aaaacttcca gtccttcatt tttcaaatat tccgtatcgc cggtgtaatt cgtataattg
    13201 tagattgcat aggcaatcgc gccatttcgg tgaatctcct cgaatgtgat ttcccactcg
    13261 ttatggcatt cgacaccagt gaaggtgacc ataggataaa gcgcgccttt taatccttgt
    13321 tgctgagcgt tgtggattgc ttgcggcagt tgattatgcc gatatttcag cagattctta
    13381 gttacttcag gtttggctaa agcaagataa agagggacag catacgcttc tgtatcccag
    13441 taagtggctc cgccgtattt ttctcctgtg aatcctttgg ggccgatatt caatcgttca
    13501 tcttcgccgt agtaagtaga gaatagttgg aacaaattga atcgaatacc ttgttgtgct
    13561 tcttcgtctc cttcgatgac cacatcggca agcttccatc gttctgccca agccgctgtt
    13621 tgctcttctt ttgcttggat ataattgttt gtctggttcg ttaattctga gacagctttt
    13681 tctgcttgct gcgcttctgg aatatctcta ctagtaagaa cgataatttc tttttccact
    13741 gaccatgtct caccttgaga taattctgca gacaagcaac catgtaatgc taaagtatct
    13801 tcgtgatagt cagggatgac tgattttcca ttaacgaaat ggcgcattgc tgcagtaaca
    13861 gtaaattgtt caatcccaaa gttgtttgga atagttttag tcgtcaaata gccgatttct
    13921 tctatagttc cacgatcaat ctcattccaa aaatgttcat catagttgct gtcttcgttt
    13981 tgaacatttc catccaattt tgatacgagt ttgactgttc cgctaccttc aagcatttct
    14041 atagttaaat agatataagc tgattctttt ttgacaatgc tcagaaaacg ttcgaaggaa
    14101 atgcgtactt tattagtaga agtagtgatt gtgaatgtac gagataatac accatttttc
    14161 atatctaatt cccagtaaaa gtcttctggt tccaaagaag ccaagtcgat cagctgatcg
    14221 ttgatcgaaa tatctatcgc gataaagttc aaggcgttga tcacttttcc aaagtattct
    14281 ggataaccat ttttccacca gccgacacgt gtcttatcgg gataccagac acccgccaaa
    14341 taagtacctt gatggtggtc ccctgagtaa gtttcttcaa agttcccgcg catccccata
    14401 taaccgtttc caatacttgt taaagattct tgcagtcgaa gatttttttt atctaattgt
    14461 gtcgtgctga ttttccatgg atcaatagca aatagtcgtt tgatctgttt catttttctc
    14521 ctcctaatga gctgttttat acgttcataa taaacgcaac cgattgcaca agtcaataga
    14581 caaaagaaaa tatttcatag aaaaaagctt aaaaaaataa atttttagga gaaaattata
    14641 gaagggaaca cacgtattat aggttttata gaatggtata gacagaaaaa taaaaaataa
    14701 agcatttaca aaaaagaaaa cgcacgctat aatacgttta acgaaaccga ttgcgtaaag
    14761 gagctaaacg gaatgaaaaa gatatttagt tttgagtttt ggcaaaaatt tggaaaggct
    14821 ttaatggttg tggtagcagt tatgccggca gctgggttga tgatcagtat agggaaatca
    14881 attcccttga tcaatcctga ttggacgccg cttgtcacaa cgggcggagt aattgaaaat
    14941 attggttggg caattattgg taatcttcat attttatttg ctttagcaat aggaggaagt
    15001 tgggcaaaag aaagagcagg cggagcattt gcagctggga tctcatttat tttaatcaat
    15061 cggatcactg gggctatctt tggtgtcaca agtgacatgc ttgcgaatga agatgcattt
    15121 acccacactc tgttcggtac gaagatcatg gttaaaggat tttttacaag tgtattggaa
    15181 gcaccagctt tgaatatggg agtattcgta gggatcatcg ctggatttgt cggggcaatg
    15241 gcttataata agtactataa ttatagaaaa ttgccggatg ctttgtcatt tttcaatgga
    15301 aagcgctttg ttccgtttgt tgttatctta tggtcaacaa tcgtggcatt gattcttgct
    15361 gtggtgtggc caaacgtaca ggctggaatc aataattttg gtttatggat tgcagaatca
    15421 caagaaagcg caccgattct agcaccgttt ttatttggaa cattagaacg tttactattg
    15481 ccatttggat tgcatcatat gctgacgatt cctatcaact atacacagct tggcggatcg
    15541 tatgagattt tatcaggcgc acaggcgggg acacaagtat ttgggcaaga tccgttatgg
    15601 ttggcttggg ccactgattt agtgaatctt aaaggtgcag gggatatgtc gcaatatgag
    15661 tttgtgttgc ataactggac gccggctcgt ttcaaagtag gacaaatgat tggttcttca
    15721 ggtatcttga tgggaatggc ttttgcgatg tatcgtaatg tcgatcctga taagaaagca
    15781 agatataaat caatgtattt ttcagcagcg ttggctgtct ttctaacagg tgtaacagaa
    15841 ccattggagt tcatgtttat gtttgctgct gtgccattat atgtcattta ttcagtgatc
    15901 caaggggctg catttgcgat ggcagatatc ttgccattgc gggtccattc atttgggaat
    15961 atcgaattgc tgactcggac accgttagct atcaaagcgg gtctaggtgg agatcttatc
    16021 aacttcgtgt tgtgtgtgat cgcttttggt gttgttacgt atttcttagc aaatttcttg
    16081 atcaaaaaat tcaactttgc tacaccggga cgtaacggaa attacgacaa tgacagtgaa
    16141 gaaaccgttg tatctaacag cggaacagga acagcagatc agcaagtggt ccagatcatt
    16201 catttgctgg gaggaaaaga aaatatcaaa gatgtcgatg cttgtatgac tcggttacgc
    16261 gtaagtgtaa atgatcgaga aaaagtaggg actgaagaag cctggaaacg agcaggggcg
    16321 atgggattga tcgtcaaaga caatggagtc caagcagttt atggaccaaa agcagatgtc
    16381 ttgaaatcag atatcgaaga tctgctgcaa tcaggagcag agattccaga gccagaaatg
    16441 gtttctacag gaaatggaca agcaggtagt aagcaatact taggtataga acaagaacta
    16501 gtttccgcag cttctggaga agtgattcct ttatctgaag taaaagatcc ggtattctca
    16561 caaaaaatga tgggtgacgg ctttgctgtt attccaacat caagagaagt tgttgcgccg
    16621 atcgctggaa aagtgacaag tattttccct agcaaacatg caattgggct ggaaacgaaa
    16681 gatggtatcg aagttttgat ccatatggga atcgatacag tccaaatgaa tcagccagct
    16741 tttgagattg ctgtcaaaga aggccaagaa gtaggaacag gaacgaaatt agctgagatg
    16801 gatcttgatg tgatccaaaa cgaagaaaaa gatccaacga tcatgatcgt atttacaaac
    16861 gataaagtag aagaagtagt gatcaagcaa ttaggtacag tgacagctgg taaagtgatc
    16921 ggctccatta aaatgtaagg agaggttgtg aaaaagctgt cctgcatcaa gtcataagaa
    16981 cagccaaaca aaaatagctc ctcctatttt tcgtttggtt gggcttatta ccgagaagca
    17041 gcagtttgaa tactgtttag tggagaggtc gtgaaaaagc tgccctgcac caagtgataa
    17101 aaacagccaa acaaaaaata gctcctggtc cattgagctt attactgagg agttagcagg
    17161 agaacactat ttgctggaga ggttgtgaca aaaattttgt cacaaccctt ttgtttcgaa
    17221 atgaagacaa ggagaaaacc aatgaaattc atgacactca acacgcatag ctggcttgag
    17281 ccagaaccag agaaaaaatt gcaagaatta gcagataaga tcctgttaga agattatgaa
    17341 gtgattgctt tacaagaaat caaccaatta ctggaatctg aagaagtaga acctgcgaag
    17401 ctaatgaagt tctgtccggt aaagaatcaa gtacctatcc gtaaagataa ttttgcctac
    17461 cgtttagttc agcttttaaa ggaacacgga aaagagtatt tttggagttg ggaaatgagc
    17521 cacatcggtt atgataaata tgaagaagga aatgcactgc ttacgaaaaa aacattggaa
    17581 agtcaggtcc ttaccgtctc ccaatttcaa aagaaagaag attatcagac acgcaagatc
    17641 ttgattggga aaacaaagat agatgatcag gacatttttg tctcgagctg ccacttttct
    17701 tggtggacag ataaaaaaag tggcttttat tttgagtgga aaaacttgga aaactacttt
    17761 ttggaaactc gcgtaccact ttttttccta ggtgatttca ataatccagt agactctcaa
    17821 ggttattata ctgtaagaga aagttgcctt cttcttcaag attcgtatgt tgtcgcgaat
    17881 gaaaaaggaa aagcagctac tgtggaaaag aaaatagatg gttgggaaca aaatacagaa
    17941 aaattgcgta tagattttat tttcgtccct gaaggaatgc aggttaaaaa atatcaacgg
    18001 atttttgatg ggatcgatag tccaatcatc agtgatcact acggggtgga aatcgaatta
    18061 gatgtgaacg aataaaaaat ataacatata acataaaaaa actgattaaa ataaaactct
    18121 ccaaacgatt ataccgtttg gagagttttt tgatcggatg tatttatccc ttttgcctaa
    18181 gcatgtaaaa gcttgtatct atgataaata aataaacata gcaaggtaaa ccagccaatc
    18241 aaagtaagag aaagaatgaa atagaaatag attggcgttt gataatgaag cgtgagctcg
    18301 ttgattcctt tttgctgctt cacgattggg gtcccgatat ctgttacttc ataatcagtc
    18361 aatgtttttc cattttgctg tagcacagtc cgatcgtaga cgataacagg gatatgaaca
    18421 gttttgtccc cagtgttttt ccacttgatt gtcaaaagac cgcctggatg tgtttttata
    18481 aaagttgttt cgttttctag tatttcttcg ttataccggt cgtatttatt gtcttttgtc
    18541 tccttataga ttggcagata gtcaggtgtg gttttttgga aaacgaacaa gctggtagac
    18601 atatctttgc tgaagaatgt tttccttgct tcttccggcg tatcgaatag ataagtatgt
    18661 cgactgacaa atgtttcatt ttcccacttt tccagatgct ggtataagtt ctggatcgtc
    18721 tgtgctgaaa aaataagaat gccaaatata cttaaaagac ggaaccactt ttgttcagac
    18781 cactggttca gtgaaagggc aaggtaaagt agaagcaata gcgtaaatgg cacgaaaaat
    18841 cgaaatggaa actggatcaa actaataaaa ggcacatttt tttcgatcaa tgtcgtccat
    18901 ggaatcaagc tagtagaaag aaaaaagaaa acaagacttg tgtacaacac gattttttgg
    18961 aataaggtgt tcttttgttg aaagaaaata aaaagcaaaa aacctgataa tatcaatata
    19021 ggaaaggcct tagggtaatg gagccaataa ctgccatcca gatctatcgc cttttgactc
    19081 atttctctgt taacaaaggg aggaagaatc ttattcccac tgtaaacaat agctaatcct
    19141 gcccaaatat ttgctgtcag aacaaaataa agcaagaccg acttaatcag ttgaagcagt
    19201 gcttttcctt tttcagtctg gttaaaaaag taataaagat aaaaagggat atacatcaaa
    19261 gctaacatga tcgaagacag taaatggatc tgtgtcataa gtcccactga gacagcgact
    19321 ttgataacag ggaacttttt atgaaggacg aaatcagcaa tagggatcat acataaagga
    19381 taaaaacaag tcccccagct agtgaatcct tggttgatag accagtattg aatagaatac
    19441 gtactcatga ataaaacggc tactggtaca cttacccaat ttcgaacatt gacatatctc
    19501 agtaaaatca gcatagaaaa tcctgaaata agataaagaa tgaaatttga aagaatctga
    19561 taatgaaacc agctacctgc aagcaacacg atcaatcctt gtaaataagc gaaaaatggg
    19621 ccgtaaacgg cattcacgat cctgccactt tgctggaatc cataaaggga aggaaaataa
    19681 tggaaatccc catatttaat ttgttgcgcg gcatcataga accgattgta atggaatggg
    19741 gcatcagcac ccaaaattag tttatgtgtg aataaatgag gcatgagaaa tgccaaagca
    19801 atgaaaaaaa ttgctaaaaa tgggccatat tttttcaatt gtcgaactcc tttgcaaact
    19861 ttagataaat tcatcatata tcctatgcga gaggtaggca agaaattaga aaattcatga
    19921 aaatatttat gaattttaca agaaaaacat aagtgaaagt tctaaggaga gaggatgcga
    19981 cataagtttt gttgcatctc cttgttttga aacagaattt ttcttaatac tcgaaacaaa
    20041 gtagcttttt catgacctct cggtaaacgg tgttcaatca gctgcttctc ggtaataagc
    20101 tcactagcct agaaaatatg agaagctatt ttctgactag cgctcttatt actcaaagca
    20161 taacgcagtt ttcacaacct cttccttaaa cggtgttcaa aagcttgcat ctgcggtaat
    20221 aagcccaacc caacaaaaaa tatgagtagc tatttttttg ggctgtactt attacttgat
    20281 gcaggacagc tttttcacaa cctcatcggc tttcattttc tatttttttc ctgaacccat
    20341 ataataaaag aaagaacaaa aaaacttgca agggaggaca catgtgaagc agagtaagca
    20401 aaaacagtct cgtcgacttt tgtttcgttt gtttttatta atatgtatcg tcgtagggtt
    20461 actgatcgct ttatatccat tttatgtgga ttctttaaat agttttattg atcaaaaacg
    20521 tatcgaacaa gtacaaaaac ggaccgcagc tgaaattgaa gtgcagcgaa agaaaatgga
    20581 ggagaaaaac caacgattaa ctgaccaagg attcaatcct ggtactgatc ctttcaatga
    20641 aaagaacaga aatgaaagta caacatccag ccaattagag gaatggctga tcggaagtat
    20701 caatatacct aagatccaat taaatatttc actttatgat cggctcaatg gtaggatcct
    20761 tgaaaatgga gcaggcgtct tgcaaggaac ctctttcccg cttggtggaa attcgacgca
    20821 ttcagtgatc tctgctcaca gcggtttacc taatcgacgg ttatttaccg aattagatcg
    20881 tttagaaaac ggagacacgt ttattttgac tgttttgggg gagaaattgg cttatcaagt
    20941 taaaaatata caagtggtac tgccagatga cacgtctgtt ctaacgattt cagaaggaga
    21001 agacttagtt accttgctta catgtacgcc gtatatgatc aacacgcatc gtttgctagt
    21061 gacaggacat cggattcctt ataacgaatc ggtaaaaaaa gaagaaggaa aaggaaatca
    21121 ggaaagaacc atgcggcaat ggtttattct tgcaggaacg ataatagctg tagtcatact
    21181 gttagtgttt atcggacgac taatctatca gtatagatta agtaaaaaag tgcttgattt
    21241 ttcatttatt attagtgatt cgtcagggaa accggtaaat ggtagttcat tcattttgaa
    21301 acataagaaa aaaacactta ctagaaatgg tgtgccgttt tcagtacaaa gcgaccatca
    21361 tgggaaagtc aagctggatc aattgcctgg tggaacttat cgaatcgttt cagctgatga
    21421 tcctaaagtt gctgtttctt ttggtattag aaaagtaaaa caagagaaga tatacttttt
    21481 tgaggggcga aaacttgtaa aagagcttca aaaaaatggt ttttatttta aaatcaatga
    21541 ataagtaagg agagaaaaaa tgatccgcac aacaacaaaa ttgtctgcca aagaactgga
    21601 atctgttcta tcgatttggc tgcatgctaa cttggattct catgaattca ttccatcaac
    21661 ttattgggag aatcaagtag aatctgttag gaaagcttta ccagatgcag tgatttactt
    21721 agcagaaata gatcaagaaa ttattggttt tgctggggtg attgatcagt ttatcgcagg
    21781 aatctttgtg aaaagggaat accggcaaca aagaatcggt acgcaactaa tgaaaaaaat
    21841 aaaagaaacc aataaaacac tgactttgac agtctatcaa aaaaatcaat cagctattca
    21901 tttctatctt tcacaaggtt ttacaattca aacacagcaa aaagatgaag cagtaaatga
    21961 ggaggaactt gtgatgaaat ggaatcaaaa cgctgatttt tgatgaacag aataacgaaa
    22021 taatgctccc agcctaattt tttgctggga gcattatttc attttgaagt cactaattta
    22081 actgtgtgaa tatgcagttg ttacaatctt tgataaacgg tgttcaatca gctgaccctc
    22141 ggtattagct caaaaaacgg caaaatatga ggaactattt ttccatttgt ttctctaata
    22201 ctcaggtcaa aacgctgatt tcacaacctc ttgataaacg gtgttcaaac ggctgcttct
    22261 cggtaataag cccactagcc tagaaaatat gaaaagctat tttctaacta gcgttcttat
    22321 tactcaaagc ataacgctga tttcacaacc tcttgataaa cggtgttcaa tcagctgacc
    22381 ctcggtatta gctcaaaaaa cggcaaaaca tgaggaacta tttttccgtt tctttctcta
    22441 atactcaggt cagaacgctg atttcacaac ctctctttca caaccttatt ttactcgttt
    22501 ataattttca tcgaagtatt ttctgctacg gatatcatct ggcattccat cgtatggttc
    22561 ttcgctaata acatcttcat tgtctatacc tgcatcaccc atataagtga tcgtagcaaa
    22621 ttcaggaaca agtaattttg gataagtttc atatttttca cgagctgctt ccatttctgc
    22681 gatatgttcg ttttggaaag taacagtgat ttctggatgt tcttcaaccc atttagggaa
    22741 aaagatcatt ccgtgaagtt tcttttcatt tggcataaag tccaatgcca cgtctgtccc
    22801 tgttggctct gtccaagtga ttttgaatac gccgtccgtc aatttaacga tatcagcttc
    22861 ttggtctttt acccaacggc ctttgaccat tccgccatgg atacggtaat caacagtatg
    22921 gtcatttttg gcataccatt catattccca accattgtca tacgtataga taaagtgagt
    22981 tccaataaaa tcttccaatt ctttaaattc tttcatgttt aagcatctcc ttataaatta
    23041 aaacatgtaa taaactacat gttttcgatt actcatttat gatagaatgg atttaaagat
    23101 ttgtcaagga gggaaaactg atggcaagaa aaaatacact tcgatatatt ttgttagggt
    23161 tattaagtaa gaagaagatg acaggatatg aattgaatca atcgttcaaa aatgaaatag
    23221 gagaattttg gcaagcaaaa catagtcaga tttatcctga acttgcaaaa atggaagagc
    23281 aaggaatcat tcagcatcaa gtagagatca caggtgaaaa attggaaaag aaagtttatg
    23341 aattaacaga agaagggaag gaacaattgg cagagtggat tcatacaccc accaatgaac
    23401 taccggttaa tcgagacgaa tttgttctga aattgtattt cgtcaaagac gtgaatgatc
    23461 cggcattagt agaaattatt cagcagcagc gtgaccttca tgaagaaaaa cgacttcatc
    23521 tattagagcg aaaaaaaacg atctttccta ctgaaaaaga aaaacatgaa aattacggac
    23581 actacctgat tttagcgcat gcgatcaatc gggaaacaga atatgcaaat tggctaacag
    23641 atgtattaga agaaagtaac cgaaaaaaat aaaaaaatat ccgaacagtg atggagaatt
    23701 cctttctata tgaaagaaac gcagatcacc gttcggatat tcttatgttc aaacaggcct
    23761 tttttcaagt atttatgtag catctactta ttaaaaagct tggtacttag gagattagtg
    23821 gcgtttagag ttcttttaac aactgttcgt agtcagcttt ttcatcgaca ggaaggagct
    23881 tgtaagttaa ttcgtctgtc tcgttgtcat gaatgatgta catcttagca ttctcttctt
    23941 tgaagttacc gatttgtaaa atcgtatagc gttcgtcgat caattcgata tctttgattg
    24001 cttttgaaaa aactttacgg acatggtgca ttttcttttg gcggatttct gccttttctg
    24061 cagcttttga caaagtaaat ccgtcatcta aatatttttt gatcagttct acttttatga
    24121 ctgtaggtaa acgatatttt ctaggacaat tcgcatcagc ttcgatcgaa cgaatgaatc
    24181 ccttttgttc ccaatacctt aattgacgtg gagacacacc tacgatatca cttaattcac
    24241 tgatgccaac aaccaattga tcattttcca acaaacgttt aagggaagcc ccaaccattt
    24301 ttgtcactcc ttttgtcctc ttgcttccct taattatatc cgtattaact tatgtgtcaa
    24361 gtaggttgac aaatagcgaa tttaggacta aagtattcta gtagtttcag aaaaaattca
    24421 gaaagaagga gaaatatgag taacaaccaa cccgtagata tttacggaaa accatataat
    24481 cggacacttt tagttgttgt cttattaatt ggtacatttt gtaccgtttt gaatcagacc
    24541 ttattgacga cagcttttcc tacattgatg aaagctttcg atatttcagc gtctgatgtg
    24601 caatggttaa cgactggttt cttgctagtc aacgggatca tgatcccaat aacagcatgg
    24661 ctgatcaata aattcagttc aagaaattta tatctttctg ccatgacgat ctttttgatc
    24721 ggaacgatta cttgctttac agcacctaat tttagtacat tactaatcgg tcgtttgatc
    24781 caagcttgcg gtgtgggagt atcgatgcca ttattgcaaa atatcatgct atctattttc
    24841 ccgccagaaa aaagaggatc agcaatgggg atgtcaggga tcgttattgg acttgctcct
    24901 gctttaggcc ctacattatc tggttatatc attgataact accattggcg tgacttgttt
    24961 ggtatggtac tgccaatcgt tgttcttgtc ttggttttag cattcttcct aatgaaaagt
    25021 gttattccat tgtcaaatcc tagcattgat attttatccg ctattttatc aacgattgga
    25081 ttcggtagtt tactttacgg attttctagt gtaggagatg acggctgggg aagcttgaaa
    25141 gtaattggtt tcttagttgt tggtgtgatt ttcatcgcct tgttctcatg gcgtcaatta
    25201 catttggaac atccattctt ggaacttcgt gtattcaaat catctacatt cacgattgca
    25261 gctgttttag ctggtgtaac aaatatggcg atggtagggg cagaaatggt cgtaccattg
    25321 tatattcaaa atattcgtgg agaatcagca ttccattctg gcttgatgtt gttgccgggt
    25381 gcattgatca tgggggctat gatgcctgtg acgggtgcga ttttcgataa atacggcgcg
    25441 aaacgtttag ccatcacagg gatgttcatt ttgacagcgg caactgcacc atttgctttc
    25501 ttgacaaaaa cgactccagt tttatatatc gtgatccttt atgcgatccg tatgtttggg
    25561 atctccatgg tcatgatgcc ggtaacgact tctggtatga atgcattgcc aaataacttg
    25621 atcagtcatg ggacagcggt aaataataca ttccgtcaaa tcgcaagctc gattggtaca
    25681 gctattttga tcagtgtgtt gacgaatgtg acaaaagcaa atatcccaag caaatctgta
    25741 ttggataata cgccattagc ttataaagat caggcaatca atgccacact gtcaggttac
    25801 catgccgcgt ttatcgtagc gatcatcttt gggattcttg gctttattat tgccttttta
    25861 ttgaagaaaa aagaacctgt tctaatgaaa gcgggggata atgcatgatt attggagttt
    25921 tgattgtcag cttgcttgct tttgctttaa cgaacgtgtt cgctaaaaaa acatggcaaa
    25981 cctttttatc tttgattttc ggactaatct tcgtcgcttc actaagtttg atcgtcgcta
    26041 atttgtccaa tcactttgga atggaaaaag taacggaaac aaaaacagaa aaaattgttt
    26101 ccagtgctga ttcccaagga gcagatatgc ttttgtataa agctttaggg aatggaaaag
    26161 aaaaagtgta tctttaccga acaaatgaaa aacaagaaaa accaaaagca actggtacgg
    26221 ataacgaaac aaataaagta gaaaagacag acggcgatgc tgaaaaagtg acgaaaacta
    26281 cttattggga atacaaaaac gacatgtata aattctggtt caatattgct gataacaatc
    26341 acgaatatga cagccgagtg aatacattca aaatcccaga gacatgggta gaattaagta
    26401 cggaccaagc agccaagtta gctgaattag tgaagaaaca gcaaagtacg atggaaagtg
    26461 aagcaaaagc ttatgttcaa gacggtatgg taaaagcaat gactgaaaat ccaaaaatga
    26521 gcaaagcaga gcaagaacaa cgtacgaaag ccttagctgc tgaattccaa caacaagcat
    26581 tcgcaaaatt agtgaaagaa gcaaaaggcg aataatattt tgaacaccat gtaggaggtt
    26641 gtgaaaaagc tgctctgcat caagcagtaa gaacaatcag ataaaaatag cactccatat
    26701 ttttcatctg attgggctta gtgccgtaga tgcaagcttt tgaacaccgt ttaaggaaga
    26761 ggttgtgagc ctgccgttta actctgagtc acaaggagca atttcaaaaa acagcttctc
    26821 atgtttgttg actattgtga cttgtgaccg aggagttggc aggagaacac cgtttattcg
    26881 aaaaaaggaa ctgcgacaag acttttgtca cagttccttc ttttttttgc tatgctatac
    26941 tagatgtaaa aaataggaga aataaaatga gggaaattta ttcttttgaa tcaaaaatct
    27001 atgcttccga agtcggcaag ggcggggcat atattatttt tccgtatgat ataagaaaag
    27061 aattcggtgc tggaagagtt aaagtccaag caacttttga caatgtgccg tatgaaggca
    27121 gtatcgtgaa tatgggcgtg aaaaatccag atggttcagt ctgctacatc cttggactac
    27181 gaaaagatat tcgtaaaaac atcggaaaag aaatcggtga tattgtagca gttacagtga
    27241 agcaaaaata aaagaggttg tgacaaaaga cgtgtcacaa cctcttgata aacggtgttc
    27301 aaaagccagt ttctcggtag taagtcaaat ttatgcaaaa atgtggaaac ccatgtttac
    27361 aaaatttttc ttactactcg aaacgaagcg gctttatcac aacctcttga taaacggcgt
    27421 tcaatcagct gtccctcggt attagctcaa aaacggcaaa atatgagaag ctatttttcc
    27481 atttttttct ctcatactca ggtcataacg ctgatttcac aacctcttct ttcataatgg
    27541 tttttcacca tctttataat aaactggttc tttgatatgg aaatctattt tttccaacca
    27601 atctaaaatc ttgtaaccta actcttctga catcggaaaa gaggcgttga tttgtgcatt
    27661 ggagatatgg tcaacatgga taccggaagt gatcgtacaa cttcccggaa cggcagtttt
    27721 gatgatcaca gctatttttt cggctaagac atcgtcttta tggaaccgac catcgtggct
    27781 agggaaacgt acagtttgca tctctgtatc acgagaaaat gtagtgactg ttccgatatg
    27841 tggtgtatct ccgcctgtta aagtgatcaa taagtcttta ccgattactt taacagcagc
    27901 ttggatcgtg aaacctagtt tggttacttc aactatcgtt tctttttcca tattaatcac
    27961 cctgccaacg ttttgaatgc tcatttacaa tttcaaattg atccaaaagt ttcattgtat
    28021 ggtgattaac aagatcttgg atcgtttgag gctgattata aaaagcagga attggtggta
    28081 tgatttgcac acctagtcgt gctaatttag tcaagttttc caagtgaatg gcatttaatg
    28141 gcgtttcacg aggaacaatg actaactttc gttgctcctt cattgttaca tcagcagcac
    28201 gtgcaatcag gttgtcgcct aaaccaacag agatacctgc gactgttttc atacttgccg
    28261 gtacgatgat cattccatcg gtcaaaaatg atccgctggc gacagcagca cctaaatctt
    28321 tgtttgaata atggtaatca aacaggcttt cgaattcagt tagtgataag tcggattcca
    28381 gctttaagtt ctgttttgcc catggactga tgattccgtg tgtttctatc atcggatatt
    28441 cttttagttt cttcactagg ttgatggcat aaatggtgcc tgaagcgcca cttacaccaa
    28501 tcacgatttt tttcttccgt tgtgccaatt gttccatttt ccgcactcct ttttatgatg
    28561 tcaaaacagt tgcagatcat tcattatttc aaatattttt cccaatcttc tacttcttgg
    28621 aattttgcac gtacaaaatg ttctttcata tcgaaaggaa ctgtaccgtc aaagatagtt
    28681 tttgcactta tcccacggaa acgaatagag ccaggattat attctggtaa ttctgatggg
    28741 tccaatggat ggttcctcat tcctgggatc acgatgatat ctttatctcc ttggaaacga
    28801 gtgttgaaag tccaaactac atcgttcatg tcgaaaatat caacatcttc atcgactaaa
    28861 atgactgtct tcaattcttt gaaggctgat aaagcaagaa tagctgcttg acgctgaata
    28921 ccttcatccg cttcgttttc tttacggatt tgcatgatgg tcatcaattt accaccacct
    28981 gcaggaggat tgtagacatt tactactttt cctggaatag ctttatcgac caaggcaaga
    29041 atacttgctt ctgtaggaat accggccata gatacgtgtt cttcactggg accaatcgtt
    29101 gtttgcatga ttggattgtc ttttcggtga gtaactgctt tgactttcac tacttgtaca
    29161 gctggattag catccccagt atagccagga aattctggca ttgcttttcc tgagttcgtg
    29221 ttgatatctt cttgcattgt ttcatttggc atgatttctg cttcaatgat gaattcagca
    29281 cgagcaatac ccacttcatc gactgctata ccatcaacga tttgaatagg ttcgttacgc
    29341 aaagctcctg cacaccatag ttcattgtag ccaagtggag tggtaggtgg ttcgaaagtc
    29401 gtgccaatgg caattgctgg atctaaacca atattgatag tgataggcat tggtttattc
    29461 aaggcttcga attgtttttg gaagtgacca atgtggcgtc cgccaggcat gatgtacata
    29521 ccgatcgtat ctttatcttc tagaaccata cgatggatcg ttacatcgct cattgttttt
    29581 tctggatctg atcctaagac tacacccatt gtgatgtatg gaccagcatc ttcaggagta
    29641 tttgtaggtg caggcaaaat gttgcgaata tcgaagtctg catcggtagc tagatgaacg
    29701 acttcttgtg ctggagcgtc tgctttgtct actttcacag gtttgattgg attttctaca
    29761 gcgtctttca agaaacgacc aagtgttcga taatcatggt gcaaaatttc acctacacgt
    29821 ttacgactag ccattgttcc gatgttcaca cgtgtgccgg ggaaaccttt gatattgttg
    29881 aaagtcatag ctggtccttc ttgagtcgga cgttttactg taccgccagc accgatataa
    29941 cggtaaacac cagataattc tgcttcagga tcgatttcaa tatctgtttc gtgatattga
    30001 cctggaagtg tttttagttc ttcgatgact tttcttaaat catacggttg atctgtcatg
    30061 agagattcct ccttagttgt ctttacctat ctatagtaaa aggtgaaaaa gaggaaaaca
    30121 attcaacttg ttcggtaaag tattctacaa tggaatggat gcgttttttt gataatagaa
    30181 taaactatga tatacttatc actaaaagaa agcgcatact tagtgttgga ggaaggaaag
    30241 tgaaaaaaat ggaggagtca tttcctaaag cagtaaaagt ggaaaatata gcgaatattt
    30301 tgaaagttac atttgaaaac ggagaagtaa aatacgtgaa atctcattgg acagaagaga
    30361 taaccgatgc cttgcaattt ggaaaaaaag gaagaggaaa aagaaaaaat cttctcgcac
    30421 tttctcgtaa tatgtggatt gggactgaag taacgattga agcagatgga acagtattca
    30481 taaatggaaa agacaggtat acgccagaag agttgtggta caaaggaaag aaaagtatac
    30541 cagaattata aaaaataatt aaaaaaaaac agcgcgaaac aaggaacata ttacttcctc
    30601 gtttcttgct gttttctact atttcagcgc tcttatgact caaatctaaa tgtggttgtc
    30661 acaaccttat tctgcacgca aagcgatagc ggcgtctttt ttcgctgcca ttcgtgcagg
    30721 aagatgaccg ccaagcatcg tcaatatagt agagacgatc actagaataa tcgcatggac
    30781 aggatttagt tgagcaacat tttttagatc cgtcatgttg tataagatgc tattgatagg
    30841 gaacgtagct agccatgcaa taaacacacc taatatccca gaagaaatac ctaaaataca
    30901 cgtttctgcg tcaaatacgc gagtgatgtc ttttttacgt gcacctaaag cttttagtac
    30961 accgatttct tttgtccgtt caatcacaga tgtataagta atgatactga tcatgatcat
    31021 acttgttact aaagagatcc ctgcaaaagc aataaggaca taagtgatag catccatcaa
    31081 tccgccagtc agttcagtca tcgttccagc taaatcagta taaatgattt tatcttcatc
    31141 tgatttgcct ttattgtaat catctagata atccaagatc ttttctttgt cttcaaaatt
    31201 gttcggataa atcatgatac ttgaaggcaa gctgtctcca cctaaataac taagcaatgt
    31261 ttgtttggca ttttcgtcaa ctttttcagt agttaagaca tttacaccac tgtctctttg
    31321 agctttgacg atttctgatt ctttgttttc gttgacgatt tgagtcgtta attgatcgct
    31381 ataagcgatt cctggagata agagattcat tgtagaagaa gatttcacgc gtaggatccc
    31441 cgagatcttc aattcatcag aagcattctg atacatcgca tcataatctg tattagggat
    31501 aaaattccca gttggaagtt ttgtatagta agtattgttg tttactaatt tgaatgttgt
    31561 accaacgata tcatcaaaat caagtttttc gtcttctttc acatcaaatc caagattctt
    31621 caatgcgttg atattagtat tattattgcc gtctacgatc agcacgacat ctgttgctga
    31681 ggctggataa cttccggcaa gtaaagaata attgtctttt aaaaagtttt ctttgctagt
    31741 gtcaagctgt gtagggaaac ttgacactcc cacacctgtc attgctgaca tcgtactaga
    31801 taaagaaaga gattccgtat caggattttg attcgagaag ctgacaggct gtactttgcc
    31861 atttacatca cgtaaaagat tgattcctgt agtacgggta aatccgatat tattacttaa
    31921 gttaggatcg atgtctgtta cgtaatcgac gtatgtttga tcaatcttat tcgtgtgctg
    31981 tgctttatct tcttcgctga cttttgcagt aatcgttttg ctgtctggat aatccgcttt
    32041 gcttgcaccc aatccggcat cgtcacgagt ctggttagtc gttaccttag aaatagtaat
    32101 cggaaatttc gccatcgttt cagcttgcgt gttatcgatt tgtttttgga atccagaaga
    32161 aagggacaga acgatcgcga ttccgatgat cccaatactg gaagcaaagg aggtcaagaa
    32221 agtacgtcct ttttttgttc ggatattgtt gaaggaaagc tttaacgctg tccaaaaact
    32281 catctttgtt ctgcgtaagt taaattgatc atcttttggt cgttcgatgt gaggatggga
    32341 atctgttaag atcttaccat cagaaaattc aatgattcga tctgcgtatt gatgggccag
    32401 ttcaggatta tgtgtgacca tgatcactaa tttttctttc gataactctt ggatcaattc
    32461 catgatctgg atacttgttt ctgtatctaa cgctccggtt ggttcatcgc acaaaaggat
    32521 atctgggtca ttggctagtg ctcgagcgat ggccactcgc tgcatttgtc caccagataa
    32581 ctgatttggc tttttatgca tatgatttgt caagccgact cggtgcaatg catcttctgc
    32641 ccgttttcgt ttttcgtctt tagaaacacc acttaatgtc atcccaagtt caacgttttc
    32701 aataatgcct agatgaccaa tcaagttgta actttgaaaa atgaaaccga tagagttgtt
    32761 tcggtaggca tcccagtcac tgtccttaaa gtctttagta gactttccgt tgattaccat
    32821 atcaccggaa tcataattat ctagtccacc aatcacattc agcatagtcg ttttaccaga
    32881 accactagga cctaaaatcg ctacgaattc tttttgtctg aaagcgacag acacaccatc
    32941 caatgctttg gtggtggttt cgccgacttt ataatatttt tttatatctt ttaattgaag
    33001 cataatcacc cttctcccgt attgaaatat tcggtatact aataagtata tcagaacaat
    33061 gatcgtagta tacgaaataa atgttaactg aagatgaact acaagaaaaa atctagaaat
    33121 ttttcaaaaa acagagggag atcaatgaat cgtattttag tagtagaaga tgatccgcaa
    33181 ttacagttgc tttaccgttc tgtgttggaa cgagcgggct tttcagtcat caccgcattg
    33241 aatggagagg atgcgctgaa aaaactagaa gcgacacgta tagaattaat cattacagat
    33301 atcatgatgc cgaaaatgga tggctatgac ttgctagact cattacgtag caccagattt
    33361 gacacacctg ttctaatgat tacggcaaag gccgattttg aggataagaa acgcgggttc
    33421 aaattaggag cagatgatta tatgacaaaa cccatcgatg tcaatgagat gatcctacgt
    33481 gtggaagcat tgcttcgacg ttcaaagatc aattacagca gtagcttgat aatcggacaa
    33541 acaaaattag agctagatgc ttatacagtg ttacaagatc agcattcgtt gattctgcct
    33601 caaaaagaat ttctgcttct gtataaatta ctgtcttatc ccaacaagat cttcactcgc
    33661 caacagttga tggatgatat ttggggatta gatacgaata cagaagaacg aacgatcgat
    33721 gtacatatca aacgtttaag gacccgtttt gaaaagacgg aagattttca aatcatcaca
    33781 gtacggggac taggctataa ggcggttatt taaagatgaa aaaaaagcta ttttcacaat
    33841 tatggatcta ttttgctagt attgtcttca tttcgatctt agtgacactg ctgtgttttc
    33901 tcggttttat tttcttattg tctcgacatt ctatctcgcc tgctgaatcg gctggaaaac
    33961 caacgttata cccgttattc gtctttgcgg ggttcagtat ggtcgtgggt acaggaatat
    34021 cgatttttgt tgggcggcgt atcctgcatc caatcagtgc gctagggaca aatatgagtc
    34081 tggtagcaac gggagatttt tcgattcgaa tggatgaaca gcagaaagta gcagaagtac
    34141 agcaactgta taaagatttc aacgttatgg tccaagaact caatagtatc gagacactga
    34201 ggaatgactt tgtgtccagt gtatcccatg aattcaaaac accactagca acaatccaag
    34261 gatatgttca attgttacaa gccccaaatc tctctgacga agaacgccaa atatttttat
    34321 atcggattat cgaaagtatc acgcagcttt cacaattaac agagaacatc ttaaaattga
    34381 acaaactgga aaaccagcgt atccaactgg aaaagaaaga gtatcgatta gatgaacaaa
    34441 tcagagaagt aatcgttttt tttcagccta aatgggagaa agaacagcta gaattggata
    34501 tcgaacttgc tgcagtaaat tacacaggca atgaagagtt tttgtaccaa gtgtggctga
    34561 atatcatgga taacgccata aagtacaatc aaatcaatgg acagattcat atcaaactat
    34621 ttgagacagc cacagagatt gtactggaag tgaccgattc aggtgtagga atgaatgaag
    34681 agaccagaga tcgaatgttt gaaaaatttt atcaaggaga tacaagtcgt caaatttctg
    34741 ggaatgggct aggactttca ctggttaaaa aaattctaga actgcatgat ggacgtattg
    34801 attatagcag tatcgaagga gtaggaacga cagcaatgat acggttaagt aaacaatagg
    34861 aaaaagaata aaacccctaa aaattctatt gaaggttttt aggggttttt agtcgttttt
    34921 ttgtgattag ggaaatgttc ttacggttct tttggcataa aaatcgctgc tttcttattg
    34981 aactacgaga aatgttagag gtgtcattga aacaaggaca tgatgcaaga aagagagcga
    35041 aagtcatgcg tcgctctctt tttttgggtg gatagatgga cagaaaatgt agggcttagt
    35101 tttcttcttg atttaaatac tcccaaaatg tatctgaagc caaagaatgc tcaccgactt
    35161 tacgagtaaa tgcaagataa ctctctgttg ttggagaaat agggagaatc acagtatttt
    35221 cttttaatag attcttgact gttttttcca taacaatagc aatccccatg tcatttgcaa
    35281 tcatattgat gatcaagtcg attcttgctc ctttataaga gatttttggt tcaaatccag
    35341 cttcgcgaca cagatctagt acaggttgat acaagttcgt agtggggcca aggagcaaaa
    35401 agttctcctt tttcagttcg cttagatcca atttcttttt actagctaaa ggatgatttt
    35461 taggtagaac tgctacaaaa tcgtctgttt cagtaggcaa ccactcaatc gaacttggtg
    35521 gggcctggaa acttctagca aagtggatcg tgtcactatg ttcattggcg tcattgtaag
    35581 ttaattcgac actttccact tctttcaact ggactgtaaa ttcaggatgg cgtttcaaaa
    35641 actcggtgat tttggaaaaa cctttataat tgatcattgt cggtatcgtt aagatattta
    35701 atgaaagatt gttgtctttc gtataggttt caagcacttc ttgcatagca tggtattgtt
    35761 ctacgacatt ttttacatat gggagcaata agcttccagc ttcggtcaat tcgatttttc
    35821 tatgggcgcg ttcgaataat ttgacgtcta attctgtttc taacgaaaga atctgtttag
    35881 aaatatttcc ttgggtggtg aattgtcgat cagcagtttt ggtgaaattc attgtttcgg
    35941 ctaaatcaag aaaaacttcg aatttatgga tatccatcat attcctccta cttattccaa
    36001 taaagaatac tttaacacaa aaaatgaatt ggtgtaatct tctctgtctg ttacaatctt
    36061 tcttgcagcg aaagcaataa ttacagaaat ttttctgatt tttttcgctt cgtagaaaaa
    36121 gagaggagtt ttttgatgcc aactggagtt ttgatcaatg taggttccgt tttgtttggc
    36181 ggactaattg gcggattagt aggaaataaa ttaagtgaac attttaaagc acagctgacg
    36241 atggtttttg gtgtgtgttc gatggggatg ggaatctatt ccattgcgcc gatgaaaaat
    36301 atgccggctg ttatttttgc tttagtgata ggaacagcga ttggtttgat tgttcattta
    36361 ggtaatggga taaataaggg ggctgcgctg atgcaagtac ctatttctaa aatcttccct
    36421 agtgaaaagc ttggtatgac ccacgatgaa tttatcagca cattagtgac ggtcattgtt
    36481 ctattttgtg caagtggtac ggggatctat ggaagtttag attctgggat gacaggagac
    36541 agtacgattt tgatttctaa atctgtcctt gattttttca cagcagctat ttttgcgtgt
    36601 aatttagggt atgtcgtttc tgtgatagca attccccaat tcattatttt ttatattttg
    36661 ttcttattgg caaaatttat ttatccattg actacaccag acatgatctt agattttaaa
    36721 gcttgcggcg gattcttgat ggtcgctacc ggttttagaa tgatcaacgt gaaaatgttc
    36781 ccagtagctg acatgatacc tgcaatgatc gttatcatgc cactgagctg gatgtggaca
    36841 aattggatta tgccactgtt ataataaaaa tcaaagagaa gccatttttt gctgactaaa
    36901 aaggatcaaa tcttttagtc agtttttttg tatttgacaa actgattttg aaactatatt
    36961 atatgttgta taatatagat tgaaataaaa tattacactt gagaatagaa ggtgacgtaa
    37021 tgcacatcca gattccaact gttcttcttg atggtactgt gctagcagca ttaagcaagg
    37081 aagatatgta tgggtatgcc ttaacaaaaa tcgtacaaga aagtctctct gtcagtgaat
    37141 ctacactata tccggttttg agaagattga aaaaagaagg atatcttgag acctatgatg
    37201 aaccttttga aggcagaaac cgtcgatatt actcgttgac accaatggga agtcgtcatt
    37261 tagaagaaat tattgatgaa tggattgttt ttcgagattc tttagaccgg ttattggagg
    37321 agagcacaaa tgaatgaata tttgaatgaa gttgtggatc atcttcaaga aattcctgaa
    37381 gacgatcgtt ttgatttgat ccagtattat gaggaatatt ttttagattc tggaaaaaca
    37441 ttagatcaga tcattgatga atatggtaca ccaaagcagt ttgccttaaa attaaaaatc
    37501 agttactttt cagaagaaga acaagcagaa aacgagttag tgaaaaatcc aaaaagacaa
    37561 attcgcctga tttggttaat cattatcggt ttatttgctt ctcctgtcct cattccacta
    37621 gcactggggt ttatattggt tattggggga ctattggttg ctttactagc gctcattttt
    37681 agtatctatg ttttatgtat cagtatctta ggtgttggcc tattcatgat catctcagga
    37741 atcagtgtgt ttggacaatc gattctgagt ggattattct ttatcggtgt cggtctgttc
    37801 gccacaggaa gcgcagtatt tatttcgcca ctgttgctga aaggaacaaa agggcttttt
    37861 tatgtcatga tgaactttgt taaatggatg ggacgacgtt ttattacaaa aagagatctg
    37921 cattcagcgg gcgtttgaag gaggacacat aaattgagat tgaaacattt tttgattacc
    37981 ggtattggtc tgatgcttac tggtggcctc ctagcaggtg caacttatac attaggcgct
    38041 caaaagagtc tgacttggga taatggtcct cggttgatcg atatggttac tgagacaaaa
    38101 aaaatcaagg atgcaaacaa aatcgtcatc catgcagaaa atcaaacagt ttcggtcata
    38161 cgcggattgg attttgagat aaaaacgact tatgataaga cagaaaagcc agaaataaag
    38221 gagaaaaatg gcgtgttgac tgtgaatgca gtcaaaaaat caacaggtgc aatcattagt
    38281 ttagaagaca caagtgcaca aatcactatt gttgtccctg cagatcatga attatctgaa
    38341 ttgacaatcg aagggaataa tagtgcaatt gatatcaacg aagtatcaat caaaaaagtg
    38401 aatactaaga cacatgatgg ctgggtatcg ttcaatgaat ttacaggagg aacaataact
    38461 gcgaaagatg aattaggctc acttcgatta gatgaggcca atgtggataa cttgatcgtc
    38521 acaggtgaaa acagcaactt ccatctagaa gacagtttga tcagcaaaga aggaaaagtc
    38581 atcctaaacg gtggcaattt atctttgcat gagatggaaa acagtggcta tactatccaa
    38641 acgtctggtg aatcttatat tgaaaaagac taccagccaa taacaaatac tttgttagaa
    38701 caaggacaga aaaagctaaa gatcactgct aaagacacat cgatcaatat tacgacggat
    38761 caagaggaca atgaaacaga ttgatcctgt actcaactgg atattttaag aaaaaacagc
    38821 aaagatcctt ccaatctttg ctgtttttca tcgcttaacg cacataacta tagtaaaata
    38881 agaaagaaaa tatctaaaaa gaaaacaggg tgaaagagta tatgaaggta gaagaaggtc
    38941 aaagagaaaa gttaaaaaca gaaatggaaa gattacatac ttatatcact caactaagcc
    39001 aaaccttcta tgatccagac aaagaaaaag tgatggttaa ttacccgaac aattcagaag
    39061 gtcgccaatt agagcaagtg taccatgaag ttttcaaaca tttattgacg gtgaagaaag
    39121 agctggatta ttattcttta ccgattatcg atacaggaat attgaagtat gatgggaaga
    39181 aggaacgatt tatctttaaa tctgttcggg aagatttgcc tctttcagca gggatggatc
    39241 tagaggtctt ggtagaagac tattttacag aagaaaagca ctgggttcga acaaaattgg
    39301 attatttacc gcaggcagcc ggagggacac aggcaagcgg ttggtacatc actgaagaca
    39361 aagagttaga actagaaggt gtaatggcgc gtattcgaaa aaaaaattaa aaaagtaaca
    39421 ttagatattt attgaaggat aaaggagcgc aggaagtagc atgagagaaa aaagagcatt
    39481 ttatatcaat ggttatgcag ggattgtcgg attggtcgta ttagctttag ttggattgtt
    39541 tttcttctat ttaggtatgt ggcaagcgaa agtttgggca ctttttttaa gtatttttct
    39601 ttggttgatc acgttattgt tgttaagttc ggcaactgta gtcagtccta atcaagcaaa
    39661 agtaattttg ttttttggac aatatttagg tacgattcga gaaaatggct ttttccttac
    39721 gatacctttg gcacaaaaaa tgactgtttc gttgaaagtt cggaatttca atagttctgt
    39781 tttaaaagtc aatgatttgg atggaaaccc catcgaaatc tcagcagtag tagtctttaa
    39841 agtcgttgat acagcaaagg cattattcga tgtagcgtat tatcaagatt ttgtagaaat
    39901 ccaaagtgag acagccattc ggcatatcgc tagccaatac ccgtatgata cattcaatga
    39961 gaatgatttg acgcttcgag gaaacacgac ggcagtgtct gacgagttgc aaaaagagct
    40021 gcaagagcgt ttagcagtag caggtgtcga agtaatcgaa acacgcttga accatttagc
    40081 ctatgcaaca gaaatcgcta gtgccatgct ccaacgtcaa caagcaaaag ccattttgtc
    40141 tgctcgacaa accattgttg aaggagctgt cacaatcact caaatggcct tagagcaaat
    40201 cgaagatgga caagaaatca atttcaccga tgatcggaaa gtccaattga tcaataattt
    40261 acttgtctca atcattacag acaaaggaac gcaacctgtt atcaatacag gcgacatgaa
    40321 agaccgtaag tgacatactt tttgtaagat aggaagaagg agtttaggac ggattattgt
    40381 cttgaactct ttttttagtt gttttaaaga aaatgacaaa attgaaagaa gaatgatagt
    40441 tgattcgaag gcagaattgt tcgctttttt ctataatcag tatataaagt aagagagaag
    40501 gggaaaaagt gaaaaaactt ctgatcggtc tacttgtttt catcgttgtg gtacttgcag
    40561 gggtgaaaat cgcagattac gtagttatgg gtggagaaga atactatgta caaattacga
    40621 cagatggtac aaaaacagtt tcaaaatcag actctggaca agaaacagtc aactatagat
    40681 atatcctgcc tggctatacg aaagagggta aggaaaaaga actggacttc aagggacaat
    40741 tgactcgacc gcttcgtaaa ggagcatatt taaaaatcac ctggaacaaa aataaaggtg
    40801 tcacttcgta tgaagaagtc gaaaaaaaag acgtgccgaa aacagcactg gaaaaactaa
    40861 ttaaagggta gggaaagaaa tgaacaaaat agtcgaagta cagaatgtaa caaaagtata
    40921 cggaaaaaac aatgagaaaa agacgcaagc attaagcggc atcagcttcg atgtagaaaa
    40981 aggcgaattt attgggatca tgggcgcttc tggttctggt aagtcgacac ttttgaatat
    41041 tttatccaca ttagataaac caacagatgg gcatatccga atcaatcaaa aagatgtgac
    41101 cacattaaaa ggaaatcaac tagcagattt tcgtgcgaat gagattggct ttattttcca
    41161 agatttcaat ttattagaaa gcttgacagc acaagaaaat atcgctgttc ctctttcttt
    41221 acaaggcgtc agaccaaaag aaatcaagca acgtgtccaa aaaattgcag aacgtttatc
    41281 catctctcat attttggaaa gctatccttc tgagatttcc ggtggacaaa aacaacgggt
    41341 cgccgccgca cgtgcattga tcacacaacc aacgattcta ttaggggatg agcctacagg
    41401 tgcgctggat tccaaaagtg cccgggatct tttagatacg atggacgaat tgaatacaaa
    41461 agatcatgta tcgattcttc ttgtgacgca tgatccgttt tctgcaagtt attgccaacg
    41521 tattttattc atcaaggatg gcggtatcca tcaagaagtg aaacgtggag atcaaagccg
    41581 tgattccttc tatcgagaaa tactatctat tcttggaaac ttggaacagt agggggagat
    41641 tgactatgct ttggaaatta tcacttactg ggatcaagag ccgtttaaga gactacttgg
    41701 tgttattctc aggattagtt atggcatctg ctatttttta catgtttgaa tcaatggcaa
    41761 gcaacgaagc ttttttgaaa agtaatacga tcgttgcggc tacagttatc attttccgat
    41821 tcggttctgt tttactaggg atcatcacat tcgtttatat tttatatgca aattcctttt
    41881 tgatgacgat gcggcaaaaa gactatgcaa tgtttatgat gctgggagca aaaggcagaa
    41941 aaatcgcaca gatgattttt tctgaaacat tcttagtagg gatcgcagct actttagtgg
    42001 gttcagctgt cggtgtagga ttgacaagta tcgtccaccg attattagtg gatcagttag
    42061 atctcaatat ttcgcatttt acacctttta gtattcacgg gttgttgatc actgttttgt
    42121 tttttgctgt tttgttttta ttagctgctg ttgtcaatgc tttttcgatt gtcaaaaaac
    42181 cgattttagc attgattcgt gcggatcaga caccaacaag aatcaagcag cataaattct
    42241 tgtttttcct tgaagtagta ctgggaattg cttttctagg ctgcggttac tatatgatga
    42301 aacacgtggg gacctatcaa gtctttggta taggggtagc cttagttacg atcgtattag
    42361 gaacttattt cattttccat tctgtgatca ttttcttttt atcattacta aagaaatcag
    42421 aacagatttc attgaaaaaa ttgaacaatt tcacattgtc acagttaaac tttcgtattc
    42481 gtgaatatac acaaatgctc tcaatggtcg ctatgctgtt tgccttggca ctgggcgctt
    42541 tgacggtagg attaggtttt aaaaatgaaa ttgcagactt gacagaaaac aattctggat
    42601 atgatctagt gatgaataat cctcgggcag aagatcagca aaaaatcaaa gaactttcac
    42661 caacactttc tgcttcttat actcaaaaag aagatgcggg aacgatttac tataatgcaa
    42721 gtgaatttgc ggctcaacca ttgatcatga taaaacatga agatggaaca ccgccgaaga
    42781 tcacgaaaga aaaagttcct gctaaaaaaa tgaatgaact gactgtacaa gaggaacttc
    42841 gaagctatga attgccggaa cagcaagaaa aagaaatcaa ggtagtcagt caatcagaat
    42901 ttgatcaact gaacttgcca caatccactt tacagctagt tcaggtaaaa gacttccaag
    42961 caaacctgaa accaatcgaa acacttgttg ctcaaaataa aatgaacaat ccatctttgc
    43021 aaaaagtaga gtacagcaac cagaaatatg aaatgtatga agtgtataat ggtctattct
    43081 ctggttttga atttatggga ttcttcctag gtttagcttt cttgaccatg cttgctagct
    43141 gtttgatgtt caagatcttg tcaggaagca agagtgacat tgctcgttat gaaatgcttg
    43201 aaaagatagg aacacgacgc gggttgctta aacaatcgat ccgtagagaa gtaggcgtgt
    43261 tattcttagc accaggaatc ttaggtgtag tccatgtctt attcggatta caaatgtttg
    43321 gtctattcat gcaaaatcca tacaaagata tttgggttcc gtttacgata ttcttcgtat
    43381 tgtatttcat ctactatgta ctgacgacat ggttatatac tggaatcgta ttgaaaaaga
    43441 gattgtgaaa aagctgtcct gcatcaagta ataagaacag ccaagcaaaa atagctcctc
    43501 atatttttcg tttggttggg cttattaccg cagatgcaag cttttgaaca ccgtttgttc
    43561 ggaaaaagag gttgtgacaa tatttttgtc acaacctttt tttcacggtc ttttattaga
    43621 atatagtaaa ttttttctcg ttactcacgg aataagctgt taagaaaacg gtttccatgt
    43681 atactggaat cagtgcaaat gaaagaaaag agggtgcaag gaacatggaa atcaatgaac
    43741 aaaattttgg cgaaaactat cacttgatta cgatcacgaa tcaaaatggg acatctttgt
    43801 ctgtcagtga tcttggggca cgggttgttc attttcaaac aataatcgat aatgaaaaac
    43861 gagagttgat cttaggtttt gatgaagcaa aagaatatct agaaaaagac ccttatatcg
    43921 gtgcttcaat cggacgtatg gctggacgga ttacgaatgg cacattcaaa ttagatgatg
    43981 aaacgttcga agtaaaaaca gacccggaca ctggtcattg tttacatggt ggtgcaccta
    44041 gctttgaagc caagcagtgg cattatacag tcatcaatgg tgaaaacgaa gcatcggtca
    44101 ttttctatca gactagccca gatatggaaa acggatttcc tggaacttta gatgtagaag
    44161 tacggtatac gctgacgaac gatgatacat ggcgagtgac ggtccaaggg atcagtgacc
    44221 gcaaaacagt attcaatcct acaaatcatg tctatttcaa tttaaccggt gatccagcac
    44281 agtcaatcga cgaacatata ctttggttga atagccgatt atttgctacg ctcaataaag
    44341 atacaacgcc tacaggagaa gtagtttcag taagtggcac agcatttgac ttccaacgtc
    44401 ctaaaaaatt aggtgaggtc tttgccagtg attttcgcca atcaatgata gtgggcggca
    44461 tcgatcatcc atttttgttg aaaaaacaat ctggtttact aaatgctgcg gaattgacaa
    44521 gcccagatga aaaagtatcg atccaagtaa aaacagatgc ttcaggaatc gtgattttta
    44581 cagcaaattt tggagaagat ggaccggaaa tgcgcgggaa taaattagta aatcatggcg
    44641 gtatcacatt tgagactcaa gaactgccag gagcggagcg acttgaaagt tttggagatg
    44701 tcactctgga acctaaccaa gtacgcgagt ttgtaacgga atacaaaata aatataaaga
    44761 aatagaataa attaaaaagg gagtgtgaca gtgtcacatc ccctttttaa tttattctat
    44821 ttctttaaag gcagatcaag ccagaatgat ttgtctaaac ttaacaaggt tagtacagga
    44881 acagttgcag ctttaactgt acgagtagtt gtttctggta tctgtcttgc cgtaaaattg
    44941 ttccacaaat cccagattga agcgacacgg aagatggaag aagcgttgtt gacgcgtttt
    45001 atcgttgaaa attctaatcc tgtgattggc acgccatctg ttgtccattt gattggcaca
    45061 tcgaatcgct tagacatatt gaggatttca gcgtttgctt cttcagttgt tgctgcttct
    45121 tttttcggtt catcatattt tgtcaggtcg tacgcttcga tgatcgcgtt caatttttgt
    45181 gaatattggc gatctgtagc ataacgtcct tccaaatatt tggttgcttc tttgtagtct
    45241 tttgtttccg acttccaagt tggtttgtag aaatcaggat tgccagtcag tccatttttg
    45301 atcaagtcgg catagtcttc caaactttcc ttgtaagaag gatatttacg gaattgtgcg
    45361 cggatttggt agctttgtcc ggaactatct tgttcaagtg tattgaaggt cacgctgctt
    45421 cctttatatg atcctttgat accaaaaagg ttatgatttg gttcgcttga taataagctg
    45481 tttccagatc cactttcaag gatagcttga gccatcatga ctgatgcgta gattccttct
    45541 ttttgcccga tttcctgtgc atcatctgca atctttttca agaactgatc agttgtttgg
    45601 ttttgactga aatggaacga gccatctaat ccatctaaaa tagatgagcc gcctgtcagc
    45661 gaacctgaag cagcaggtaa acctgctaag tttactcgga cagcaaaatc aggcgtgaaa
    45721 tctgaaatag aagttactcg aactttatct cctggttgag gcgcatggat aaattgtccg
    45781 ttcccaatat agatacctac atggtgagta acaccggaag aaggtcccca gaagacgagg
    45841 tcgccaggtt gggcctgact tactggaatc tgcgtacctg catattgctg ttcgcctgtc
    45901 cagccaccga tataatgacc ggttgctttc atatatacgt aataagtcaa accagaacag
    45961 tcaaaagtat ttggaccttt tgctccccat acatatggtt ttccaagatg cttgaatgct
    46021 tctcgaacga ttgcttgttg gacattcgtt gtatttgtag gcaatacagc atcaattggt
    46081 gattttacaa caaaatcaga agaagcagaa gatggattct ctataccgct ttgatttgct
    46141 gtatttggac gagatgaagc attgttcgtt ccgccattcg atgaaccatt gtttggatgg
    46201 tttggttctc tctgagtatt tccattgtta ttcgatccag atgggtttgt ttgattcgaa
    46261 gaattcccgc tgttcgaatt attgttatta ttgtttgaat tatttgaacc attattattg
    46321 ttgttattac ccacatctgg tttgtttggc gtttccggat ctggtgtact agggacttct
    46381 tcactaggat cagttggttt ctctgttgaa gtatccggtc cagctttaaa ttctgcagta
    46441 atagataaat tgttcgtacc tactgtaaag gtctttgcat cataatttac ttctttggca
    46501 ccattaacag cgactgaagc aatttgttca ccttcagctg gcgtaatagt gtaagttacc
    46561 ttcgtttccg ctaataaacc ttctaccgtt ccactttccg taatatccaa aggttgctgt
    46621 tcaggggaat ccgctgtcga agcagtcagt tggatcttac caatcaaaga aggagcaatt
    46681 gtaagggaat atgtctcggc tggcttttca ttttctgatg gatcagccgg atcaatttca
    46741 gttggctcgg tcgatcctgt tgttgagtta gttgttccag ttgggtcttc tgtaaaagaa
    46801 tccgttgttt cactagtagc tgagctggat gtagtcgtat ctgttgtgac tgtttgatca
    46861 gctatttgat tatctacggc aaatacggta ttggtcgaca aaacagacgg agcaatcagc
    46921 caagtagcag ctagcaaacg tatcgttttt ttatttttca taataaacta gtccttttcc
    46981 tttcattgat tttctgtctt attcagcatt cattagacat tttttggaac agataatcgt
    47041 gtcgaaaagc tttttctttt cataaatctg tctgtgtatt ctaaataaaa caatttgtaa
    47101 ataagcaacg agcattcatt cgtttttctt tgacgttcat tttattgcat agaccacctt
    47161 tgtttgggga taaacaagtg gggataaaaa tggttatgca tatgtaaatt ataccaaagt
    47221 ttggaaagta tcacaaaaat ttataaaaat aatgatccta aaaagaaaaa gactgaaata
    47281 tgtgataaac atctcatact tcagtctttt tcattaacta ttcataagac attaggtctt
    47341 catcaaaccc gctaacgaga gtagtgatca ttgctacgac tagactaaca gccagtcctg
    47401 ctaagtacca gaaaaaagta ccggaaatga atgcaggcaa tgtggtcaga ctaccaaata
    47461 caaaagcgat cgctttcact tgggcaaatc ccattacagc tccaccagca gctgcaccaa
    47521 tgcaagcagc aacaaatggt tttttcaatg ggatcgcaat tccgtaaaca gttggttcgg
    47581 tcactcccgc aagtaaaatc gaagcaaaag cagaaccgga gatcgaacgg gtttttgaac
    47641 gtttacttcg cagaaataca cctaaagctg caccagccat tccaaaattg gctgctcctg
    47701 tcaacggaac gattcggtcg aacccataag cagagatatt actgatcatg acagggttta
    47761 cagcccattg gataccaaat attaccaaaa tattccaacc accagcgatg attgcgccac
    47821 tgatcggtcc gttaatatcc atcatccaag taattgcggc agctaaacct tcgccaaggt
    47881 aaacacccgc aggcccgaat accattaacg tcaaaggaac cgtgataact aatgaaagta
    47941 aaggtacaaa tactaattgc atattttcgc gaatatattt tttgaggaat ttttcaacaa
    48001 aagaataaaa gaaaatacct aaaatcgccg gcatgacagt agacgtatac tgcatcagta
    48061 ctacaggaat ccccagaaaa tcagtagctg ctttgccact gtctgaaagt aaagaggtca
    48121 gattcggttc aatcagtgct gcagcaatga cagccgcaat atatccattc actttaaacg
    48181 ttttggcagc agaaaaagca agaaagattg gcagaaaata aaagacggca ttcgacgcag
    48241 cagacaaaat atgataagtt ccgcttgttt cactaagcca gccaatcgta gtcgctaaaa
    48301 caaccagacc ttttaatata ccagaaccgg caaacagcgg aatgatcggc gtaaagattt
    48361 ccgatatcaa accaaatagt ttttcgatcg gatttagctt ttctttcgga gctgaatgat
    48421 cgatttgacg cgtcaattcc ttgtaagcag gagccaatcc ctgatccatg attatttctg
    48481 catatctatc gagtaaaatg aaatacttaa tggaagggat ttgctgtttt aatttttctg
    48541 cattggctac tggctgtttt ttcaatttga tacgaagccg agtcgcacat ggaaggacag
    48601 aatcaatatt gtcttttcct cccaactgtt caatcagcat atgaatctgc tcggacagta
    48661 ccatctgttc aggattcatt gtcgtttcca ttagaagacc actccactca ctaatataat
    48721 attggcgtaa ggtgtcattt cgcctgtacg aataaatgca tgacagttat tcaactcttt
    48781 tttcatttct tcatgtggga taaagctaat cggtgtatct ggtaacaata atttgatttt
    48841 ttccaatatt tccgggttca ttgtctttat ttcttccgcc aattcaatcg attgtacctc
    48901 aagttcttct aaaacgtttt ctaaaacaga taaaaaactt ggaagaccgt ttgagacagc
    48961 caaatctatt ttttcagtac caaaggggac aggcatgcct gcatccccga tacttaattt
    49021 atcaaagtgc cccatttgtg cgattactcg tgaaatatct gaattgatta cttttccttt
    49081 tttcatgttt gtttcttcct ctcattgtta attttagact gctgattgtt ctaaagcttc
    49141 gcggtaaggg atagaaggtt gcgcaccata agactgcaca gcaacagaag aggctagatt
    49201 tccataaagg atcgcttctt tcaagttact aaggtctggc tgaagtgtgc tgcttaatgc
    49261 gccaataaat gtatcacctg cggctgttgt gtcaacggca tccactttaa aagcagggac
    49321 gataccgtgt tctttttctg tatgatagaa agcgccggca ctgcctagtg taatgattac
    49381 tgttccaata cctaattcat ggagtttttc ggctgctgcg accaaactgt tatgatctgt
    49441 cactctgatt cctgtaatga tttctgtttc tgtttcattt ggtataatga tatctgtctt
    49501 ttcaagtagt tcagtaggaa tcgtttcacg agctggtgca ggattcagga tcgttgtttt
    49561 tcctgcgtct tttgcaatag aaaaagctag gatcgtcgca tctaagctac tttcaaactg
    49621 agcaataata aagtcactgt ttgtaatcag ttgcttgttt tttaggactt cttgttcatg
    49681 gaaagcatta tttgcccctg catggatcaa gatactattt tctcctgctg cgtctaccat
    49741 aatcattgct tgtccggttg tggcgccttg gatttcagct atcccagatg tatcgatgtt
    49801 ttcttttgtc agtagatcta ataactgttg tccttcgctg tcagccccaa cgcctccaat
    49861 aaaagatgtc cgtgcgcctg aacgtttggc tgccactgct tggttggcac ctttacctcc
    49921 gccagcgtga aaaatctcat gcgcatgcat cgtttcgcct ggcttgggca tgttggttaa
    49981 acgaagggta gtgtccatat taatacttcc aattactgta accgtgttca ttttacaaac
    50041 ctccaactat ctcatttatt ttgatgggaa aattattttt taaaacgttt tagtaaaacg
    50101 ttttaatagt tcgataaaaa tatagcacac cttgaaagct atttcaaggg tgcagttgaa
    50161 aatctttttt ctaatcgtac aggtaatctt ttttcttccc attctttttc tgggaattgg
    50221 atccgatcta acaataactt ggcagatgtt tgtcccaatt cgaagattgg ttgtgcgatc
    50281 gttgtcagtt tcggcttgat atactcgcac atatctatat tatcatagcc aataatgctg
    50341 tagtcttcag ggatgctttt tccagcttcc tctaatccgc gatataatcc aaaagctaat
    50401 tcatcattta aagcaaacac accagttgca gcagaatcaa gaagttctgc tgtgatctgg
    50461 tagccacctt gttttgagaa ctgtgtaggt aagaggatca gttggtcgtg agggatttgg
    50521 taaacatcaa gagcagattt aaacccctca atccgagcgt ggacattttc cggtggattt
    50581 tcaggataga caagggcgat cgtttgatgt cctagactaa gcaagtgcat gcccgctagg
    50641 taaccaccgc gaaaatcgtc tgttcgtacg gcatcactaa atccttcaga ttttttctga
    50701 tccaaaacaa tgaagggccg gccttgtttt ttcaaatttt cgttgattgc atctgtagag
    50761 acagcagaag tcgcgataat gaatccatcc acacctcgac gtgtgagctc ggctagatat
    50821 tcgatttctt tttgatgatc agaatcagca ttacataata tcgtgacgaa attctgctta
    50881 tacaagatat cctcaattcc tcgcatcagt gtactgaaga atggattcgt gatatcagga
    50941 acgagtacac caattgtttt cgtttccttg gtaatcattt gtctagcaaa atagtcaggc
    51001 tgatagccta attcttcttt ggcagctaaa actttctgaa cagttttcgg actgaatttc
    51061 tccgtatttc catttaatat caaggagaca gttgtgattg aaacgccgga aagtttagcg
    51121 acttctttga ttgtgatctt ttttttcacc atgttcatac tcctatctaa atcctgtggt
    51181 tattttccca tgaaatcaaa aagaagtaaa tgaaaatcac gtgtgccagt acttatttgc
    51241 tttgttggat agcttcgatt atttgtttcg ttgagcgtac tcgtgcagtt ttcggaaata
    51301 tcttttttat gaacaattga tgggattctt tgtcacgatc actgcaagca tcttcagcaa
    51361 gcacgatatg gtacccgtgt tgaaaggcat ctaatgcagt agcatataca ccgtttgttg
    51421 tcgctacacc gcttaaaatg atagtttcga ttccacgccg gcgaagttga agatcaagag
    51481 aagtaccaaa aaaagcactt ggattgtatt ttgtgatagt caacatatta tctgtatctt
    51541 tcaaagaatc cttcaaaagt aaatcagtga attctggagg tacagaagca gtcattccac
    51601 ccatatcagt ttgttgactc aaataaggga aagtggagat gtctacgttc actaaaactt
    51661 tcaaggcagc ggtacgtttc aatgttctta ctaacaaatc attgtttgtc agaatagatg
    51721 ctgcagtgtg tggagagagt gtaccgttat ttacgatctc tttttgcatg tcgatcgcga
    51781 caaaagcagt ttttgataaa tcaaaaatca tattttcctt taaatcattc atgatgttcc
    51841 ttctttcaaa taacaatgtt ttttatgtaa gtaaatcata aatcgtttat ttgtcaacta
    51901 aattaaagga ttcctttctt tagtctagag aaattcagtg gtaaaataaa taagtgtgag
    51961 aaaacgcatt cgatgcatag atatagcgag aaatatcgtg aaaatggagg aatcagagtg
    52021 aagtatgtcg aagtaaaaaa tgaatacaaa cgatacaaaa tgggagaaac gaccattaca
    52081 gcaaatgacg atatttcttt ttcaattgaa aaaggcgaat tagtgattat acttggtcca
    52141 agtggagcag gaaagtcaac gattcttaat attttaggtg ggatggatac acctgatgaa
    52201 ggtcagatca ttattgatga cacagatatt gcgcaatttt cagataaaca gcttactgct
    52261 taccgacgaa cagatgtagg gttcgttttc caattctaca atctcgttcc taatctaaca
    52321 gcaaaagaaa atgtggaatt ggcaacggaa gtttctcctg atgcgcttga tcctgtagag
    52381 gtattgaggc aagtgggcct agctcatcga ttgaataact ttccgtccca attatcagga
    52441 ggcgaacagc agagggtttc aattgctcgt gcactagcta aaaatcccaa acttctttta
    52501 tgtgatgaac cgacaggcgc gctggatttt gaaacgggca agcaagtatt gaaattattg
    52561 caaaacgcta gcagacaaca cggcaatacc gttttgatca ttacacataa ttctgcttta
    52621 gcgcccatcg ctgatagagt cattcacatt aatgatgcta aagtaaggtc tgttgaatta
    52681 aatgatcatc cttcatccat tgatgagatt gtatggtagg gggattttat gaaaacaaga
    52741 acatatctta aagcaggttt tcgcgaaatt cggcaatcta aaggacgatt cattgcaatc
    52801 atccttattg tcatgctagg aacactttta tttgtaggtg tcaaaactgc tggacctgtc
    52861 atgcaaaaaa cgatggatca ctatgttggt acagcaggac tttctgattt gcaaatcgtt
    52921 tctactggtg gcttgacaca aaaagatatt gctcaagcag aaaagatccc agatgcaaaa
    52981 gtagaaacag gaaaacagat ctattattcc aatactggca aaaacgaagt gattcaaata
    53041 ttttcttata acaaaaataa caagcagaac aagctacaat taactgatgg aaaactcccg
    53101 gaaaaaccaa accagcttgt attggatgaa aaagcggaag atgaagggta taaaatcggt
    53161 gatatttatc agattgattc agatgaattg aaagaaaaag agtataccat cacgggcttt
    53221 gtccgttctc cattgttcat caacaatttg gagagaggat acgcgaacgt cggaaatggt
    53281 agcgtcgatt attttgtcta tttacctgaa tccgttttta aaacagatat ttattctgtc
    53341 ttatatcttg attttacaaa cgtaaagaat ttgaatacgt acagcaaagc ttacaaagat
    53401 aaaatggagc aaaatcaaga aaaggcagaa aagtatttac aagatcgacc cgaagaacgc
    53461 ttagaagagc tgaaaaaatc ggccaacgaa gaattagaac cggcacagca aaaaatagcg
    53521 gatggcaaag cacaaacaac gcaagcaaga acacggttag aagatgctaa aaaacagtta
    53581 gcgcaacagt cagcaactat ccagcagctt cctgaagcgc aacgaacaat cgctgttcaa
    53641 acattatctc aacaagaagc tcaacttgct gaacaagaaa ggcaattagt tgagaaagaa
    53701 cgtgaactgg cctctgcaga ggaagaattg aatcgaaatg cagaaaaaat tgaaaattta
    53761 actaaaccat catacctata caatgaacgt tcagaaaatg tcggttttca agaatttggt
    53821 gatctgtctg atcgtatcgc tgcgattgcc aatgtttttc ctgttttctt tttctttatt
    53881 gccgcattga tcacctttac gacaatgaca cgtatggtag aagaaaaccg cagggaaatc
    53941 gggacattaa aggcgttagg ttatacgaaa gttgaaatcg caaaaaaata tgcaatctat
    54001 gcaagtctag cctcagggat aggtattgtt ttaggaacga tattaggaac gaatcttttg
    54061 ccaaggatca tttttgagct gtctaacgag cggtatgata ttgggagtgc gcttattttt
    54121 tatgactggc cgccgatttt acaagcagct gccgcattct tcattgccgc atttggcgct
    54181 gcaatgatcg ttttattcaa agatttaaga gaacggcctg ctgcattgct tcaaccgaaa
    54241 gcaccgaagc cagggaaacg catttttctt gaatacatca ctccgctgtg gtcacgcctt
    54301 agctttaatc aaaaaatcag ttaccgaaat ctcttccgat ataagtcaag aatgcttatg
    54361 gcgattatcg gaattgctgg atgtgccggg ctgatggttg caggcgtggg attgaaagat
    54421 tctctaagtt ctgtttcagc caaacaattt ggaccgatca ttgactatca agcaatcgtt
    54481 acattggatt catccacgga agatagtcgt caaaaagcag cggatatgct gcagaagcaa
    54541 gaaaaagtaa atgagatcct agctattcat actcaaaccg tagaattgag aaaaaaagga
    54601 catgcttcgc aaagtctgac agtgatcgta ccaagtaaaa cagctgattt ggatcgtttt
    54661 atccatttaa ctgatcttga agagaaccca cgctccttgc ctaaaacagg aatcgctatt
    54721 acgcaaaaag tagcagaact atttgactta tctacaggag atcatatttc gctttatgat
    54781 gaagatcaaa aagaatggaa agtcgaagta aaagaaatcg tgaaaaacta tctaggtagc
    54841 tttatttata tgtcccctga atattatgct tcagttactg atcaatcgat gatggataat
    54901 gcatttttgc tgcgtacaga taagatgaca acaaaagaag aagaaatgct ttccgagaaa
    54961 ctgcttgcca cagacgctgt gacaaatacg tctttcatgt ccaaacaaat cgaaacgcaa
    55021 gaagaatcaa tggcgaactt agactcggtt gtcttaatct ttgtcgtatt atcaggactg
    55081 ctggctttta tcgtcttgta taatctaact aatatcaata tttccgagcg tgtacgcgaa
    55141 ttatctacaa taaaagtcct tggatttttt gataaagaag tcacgatgta cattgttcga
    55201 gaaaatatca tctttactct tttaggaatc atcggaggat ttggtgtagg atatatattg
    55261 actgacttca tcttgcaaca agcgtctatg gagaatgtca tctttccatt agtgatcaca
    55321 tggtgggctt atgtcttatc agcaggatta actatcgtat ttacggttat tgtgatgatt
    55381 gttacccatt tcaaattaaa gcatatcgat atgattgatg cgttgaaatc gaatgaataa
    55441 aaacagaggt tgtgaaatca gcggtttgac ctgagtatta gagaaacaaa cggcaaaata
    55501 gtttttcata ttttgccgtt ttttgagcta ataccgaagg acagctgatt gaacaccatg
    55561 aatcagaggt tgtaaaaaag ccgtcctgca tcgagcaaaa agaatactca aataaaatta
    55621 gctcctcatg ttttacattt gagaagactg attgccgtag ataaaagctt ttgaacacca
    55681 tttatagaag aaacaagaat attttgctat tttaaacaag aggatagaca aatacatgtc
    55741 tgatctcttg ttttttattg ggcaacagac ctcttagaat gtataaagat aaattttaca
    55801 aacgctttcg gttcagttat aataataaat gataacttgt atatataagt tgtggtaggt
    55861 aataaatcag ttgaatggag gtaaatatcc atgacattta aagacaaagt catttaccaa
    55921 atctatccca aatcttacaa agacagtaat ggtgatggaa ttggagattt aaaaggaatc
    55981 aaagaaaaac tcccgtatct gaatgatcta ggcatcgaca tgatttggct aaaccctatt
    56041 tatccaagcc ctcaaaaaga caacggttat gatatctctg attacacagc catcgatcct
    56101 atctttggta cgatggagga attcgaacag ctaatagccg aagcaaagaa ataccggata
    56161 gaaatcatgc tcgatatggt gctgaatcac gtttcgacag aacatgaatg gttcaaaaaa
    56221 gcactagcag gggaccagca ttatcaggac ttcttcattt taagagaaga gccaacggat
    56281 tgggtatcaa aatttggtgg aagtgcttgg tcgccatttg gagatacggg gaaatattat
    56341 ttgcacttat atgatcggac acaagctgac ttgaactggc ggaaccaagc agtaagagag
    56401 gaactattca aagttgttcg tttttggatg gaaaaagggg taaaaggatt ccgtttcgat
    56461 gttatcaatg ttatcggtaa agacgaacaa ttgaaaaata ataaagaaaa tgatggcaaa
    56521 cctgaatata cggacaaacc aatcacccat acgtatctaa aagaattgaa ccaagcaacg
    56581 tttgggacgg attccactat catcacagtc ggtgaaatga gctctacgac gatcgaaaat
    56641 tgtatcttgt atacagaacc tagtagagaa gaattatcaa tggtctttaa tttccatcat
    56701 ttgaaagtcg attatgaaaa tgggaataaa tggtctactc ctccatttga ttttgcagaa
    56761 ttaaagcgac tatttcatac atggggagaa aagatgagtg agggtaacgg ctggaatgct
    56821 ctatttttta ataatcatga tcagccacgt gcgctcaatc gatttgtagc tatcgatcag
    56881 tatcgaaaac aaggagcaga gatgctagca accatgatcc atttgaaccg tgggacgccc
    56941 tatatttata tgggagaaga aatcggcatg atcgacccag actattcatc gatttccgac
    57001 tatattgacg tagaaagttt gaatgcttat aagttactcc ttgaacaagg attcacagaa
    57061 aaagaagcgt ttcgtcggat caaagcaaaa tctcgcgata actctcgaac acccatgcaa
    57121 tggtcagaca cagaacaagc aggatttact acagggaaac cttggttaaa agttggaggc
    57181 aagctagaag agattaatgt agaaaaagaa ctatcttctg aagattctat tttgtcctat
    57241 tacaagaaat tgattcggct gagaaaaaca tatccaatcg ttgcacaagg agattatcat
    57301 gcttatgaag caaatcatcc ggaagtttat ggctttcttc gccaatttga aggacagcag
    57361 ctgcttgtat taacaaattt ctatgataaa gatacaagga tcgccatccc agaaggattc
    57421 acagaagcca atattcttat cgataattat tccgatactg ttcttcatca aagtctggag
    57481 ctaaaaccat accaggcaat tgctttgctg aaaaattaaa acaaaaacac aaaacgtcgt
    57541 tcctacgagc tattctcgta agatcgacgt tttgtgtttt atttaaaata atcttcttca
    57601 gaaaatgaag agttttcata ctctccttta tcgccataaa atttattgta gcgttgtttg
    57661 aatttacgga aaataaaagt aacgagtaat ttgactaacg tatagatagg aataccaaaa
    57721 ataacgccca caattcccat tagatcaccc atgacaagta aaacgattaa gatcgtaatc
    57781 ggatggatct gtaaacgatc acccattact cgaggaatca ccaagtcacc gtggagaagt
    57841 tgtacggcaa accagacaat gacaaatttg acagccataa aagtagagtc ttggaatgca
    57901 atgatcaaac ctggaaagaa ggcgataaac ggcccaatat atggaatgat acataacaac
    57961 ccagcagaaa tagctaaaac actagcaaat tctaatccga tcagtaagaa acaaacccag
    58021 tagactgctc caaggataaa tgaagcaatg atttgcccct ttagaaatga acccaattgt
    58081 tgattagcaa tctttgtcaa atttttaaaa tctgtacgaa atgctggtgg gacaatcgct
    58141 aaaactgact gataaaattt ttgaggatct ctcaaaagga aaaaagcgac aattggacca
    58201 gtaaataaag taataaaaat agctgtaaca gttgaaaaaa tgttgctgat ccgttgtgcg
    58261 ccactttccc aataatttcc aataaatcca gctatatcag acgtcacgtc gtcaatagaa
    58321 gcgaaaaatt gattaaatga atcggcaaaa ggtgttttct ccaaaaattg tcggagactc
    58381 tcttgaaaat cttgaaacaa atctggcaaa ctactgatca atgtctttgc ctgttcttca
    58441 agaaaaggaa taagccatat gcttccaagc cccaataaaa ataaaataat cacataaacg
    58501 ataatgactg acaagttcct cgaaaggtgc ttgctcaaac gtttgatgac tggttccaaa
    58561 agataataca agatcagtgc aaacaataat gggggcaaga tagtagcgat aatgattccg
    58621 acaggcttga atataaacga gatctgatgg aaaaaataaa tgatcagcgc aagtaagata
    58681 actattccta aaacatagta agaggttttt cctcctaaaa agcggatcaa acgattcgtt
    58741 gtatctgttt cttttttcac tctttttcct cctttatcta taacttcatt atagacaaaa
    58801 gcgggtataa aaggaaaatg atagaggttg attgcaaaaa tatcgtcaat cattcatata
    58861 aactttctca tcaattaaaa taagaaaacg cttgacagtt cttttaacca tatgataaat
    58921 taaatcctgt tgctaaaacg taactattac ggtttgcgaa aagcgaatcg gaacattcaa
    58981 atgaaagaag atgagaagag gagtgtcata aatgaaacga ttgataggta tattggccat
    59041 gctggtttta gcaggtatgt taactgcttg cggggcaagt gggaaagccg aggacagtaa
    59101 agaaaaattg agcgtgatga cgacctttta tcccatgtat gattttacaa aagcaatcgt
    59161 cggggatgaa ggagaagtag agttattgat tccagcaggg actgattccc acgattatga
    59221 accttctgct aaagacatgg caaagatcca agatacagat atctttgttt ataatgatga
    59281 aaacatggaa acatgggtcc ccgcaatcca aaaaacatta caagaaggca atgtccatac
    59341 gataaaagcg acagaaggta tgcttttact tccgggaagt gaagaaggac atgatcatga
    59401 ccatgaacac ggggaagaag gccatacaca tgagctagac ccacatgtat ggctagctcc
    59461 aagtttagca atcaagcagg tagcaaacat acgtgatcag ctgattgaag cttacccaga
    59521 aaaacaggaa gtatggacaa aaaatgcagc agcctatacc gagaaacttc aagcactcca
    59581 tcagctttat caagaaacct ttaagcaagc aaaacaaaga tcttttgtca cgcaacatgc
    59641 tgcattcaac tatctagcgt tagaatatgg attgaatcaa gtatcgattg ctggtctttc
    59701 ttctagtgaa gaaccgtctg cggcgagaat tgctgaactg aaacactttg ttaaagaaca
    59761 tggaatcaac tatatttatt ttgaagaaaa cgccaaagat agtattgcca gaacgttagc
    59821 aaacgaagca ggtgtatctt tagaagtatt gaatcctttg gaaggattga cgaatgaaca
    59881 aatagaaaat ggagaaaact atctttctat catggaagca aacctcgaag cgttgaaaaa
    59941 aacgacagag acagaaaacc cgctagaaga tactttgacc cccaaaaaag aaaagagcgt
    60001 ctacaacggt tattttgaag acgaggatgt acaagatcgc tctctttcag attgggcagg
    60061 aacttggcaa acagtagata cgtatgtaga agatgggact tttgatcctg tttttgaata
    60121 taaagaaaaa ttgaatcagg ataagacagc acaagaatat aaagaatatt atacgaaggg
    60181 ctatcaaaca gatattgctt caatcaagat cagtgagaaa gagatggcat ttacgtttaa
    60241 gaatggaaca acgaaacgtt caaattatcg ttatgtaggg aaagaaatct tgacctacga
    60301 ggcaggaaac cgtggcgtaa ggtatctatt cgaagcagaa gataaggaaa gtggcgcttt
    60361 tagatatatt caattcagtg atcacacgat tgcaccggct gactccgaac attttcattt
    60421 atatgcagga aatgaaagtc aagaagtatt gctgaaagaa atggagaatt ggccaacatt
    60481 ttatccagat acaatggatg gacgtgaaat tgcacaggaa atgcttttgc actgataggc
    60541 aaaaaagaac cgaagggttt ggatcggctg gtcatttagt cggtccaaac tattcggttc
    60601 tttttatgaa atcaatttct ttaatccacg gatagaggct gggatggtct cgccgtttgc
    60661 caacgtgact tctctggttt ttttattaat cgaccgcaca ttttgtgtat tgataacata
    60721 ggatttatga caacggataa aattccgatg cattttctcg atttctttga tcttctcata
    60781 gaattgtaat tgggcatgag tcaaatggac ttccagttta tgtggcgctc ctagcgaagt
    60841 agaaaaatat tggatgtctt tgatcggtaa aaatttgatc tcatcattaa actctatttt
    60901 gaagatatct ttttggattt gggacatttg aaaatcttcg aaaattttgc tcaggatatg
    60961 ctcgacattt tcttttaaat cataaagatc ttctttgacg atataatcag tcggttcgat
    61021 gttgcttttt aagattttca tcgacatttc cgtatgggaa gtcacataga ttatttttcc
    61081 taaaggatct aattcacgga tcaatttacc gatcgctaca ccatccattt cactgtcttc
    61141 tagttcgata tctaaaaagt aaataccaaa agaagaagtt ctgatcttgg ctgcattgag
    61201 aagttcttcc ggatcagagg tagaaatatg gacataactg tctaagtttt caatcatgat
    61261 tctatttttg atcaccgttg ataaaacttc taattgtttt ggatcgtctt cacaaatata
    61321 aatgggaatc atatcattac tcctttattt tatttgtata taaatcgttt gagaaaaacg
    61381 ctggttttca attgatgttt caaggaaaag ataaggattg gtctttgtca attcatccaa
    61441 gataaacaag ccaaggcctt cgttttttgg atttgttttt gttgagaacc ctttttgttt
    61501 caactggttt aacggtaatg tatttgttgt tgtattgatc acacgaatca tcacggaatg
    61561 attcttcttg agtatggtca attcgatttt tttcttcttt gcagcactag ctccttcaat
    61621 cgcattgtcc aagataatac caagcatacg tacaaggttt accgtatgtt tcgtatccag
    61681 ttcgattggc tcaggaaaat gaagctggac gatcaaccct ttttcctgtg ccatcatgag
    61741 ttttaatgac agtaaactac ggatctcagg aactttcata ttatccaaca tacttagatt
    61801 ggccggaaaa aggttcatca tctggcgtgt aggtaatatc gtttgatcat aataagaccg
    61861 taatccttct aagtcgcctt ctgaaatata gctgtgaaga gaaaaaagca gattttggta
    61921 atcatgtttg aattctctca agtcttgata gtttttttct agatctttga tataatcctg
    61981 ttgcatcctg acttgttgct ctaataactg atcagctaat ttcttattag agattttcca
    62041 ataataaacc aagatgatca ggccaacaca cagatataga atgaaaaaac tcgtattcaa
    62101 agctaagaca tcaggtgttt caccagaaaa acgggtataa aaaataatga tatagtatgt
    62161 aaataatatc aatgtcccga tcgtaccgat catacggcgg tccacagtgt gaaaccaagt
    62221 ctctaacgat ttttttaaac aaaaagctaa taaagcagat aaaaaagcgg ataagacaat
    62281 gtgaaaatac tgcaatgaat ctcctggttc aataaccgaa gatttcaaaa caaaaaaatc
    62341 gccgatgctt gttaagtgat ctcctaaaag cgacgtcaat aacccaaaag gaagcgcgta
    62401 aaccaattgt tgacgcgaag tcgaaaagaa gaaaaaagta agcatcagca ttcctatagc
    62461 aattagagca gtaaaaatcc ctaaaatcga atagacccat ccaatcaaaa tacaagaaat
    62521 cagaatgact cccgcaaaca gatatttgta tcggatgtga tggtcaatca ataagataca
    62581 aattgtgtaa atcaaatatt gcaacgctat ggaccataaa aacataaagt acagctccca
    62641 ttgattttta ccaaattata gcacaattgg cgtattattt ttttaatttt tcagggattt
    62701 tgaattcaga actcatacca aagcagcagc cagatacaaa aaagtcagat aagttagtta
    62761 attgtttaat gattgttttt ttcatgaaag attcctccaa aattcatcaa gtagtttgta
    62821 ataggaagca acgtagctat ttctaaaaca atcccaagta gcaaataggt agaaaagtaa
    62881 gaagctgaga aaaataacgt aatgagagaa aaaattagaa acatgctgat cgccttcttt
    62941 aataatgggg gacgtttctc gggttcaatg ggattgattg ctgtacctct tgatccatag
    63001 cgaagcagta acaaaaagca gctgattaac aaaaagacca tcattgggaa ggagatagtc
    63061 aattgcagat gtttcatcac caagggaacg ccccataaat aaagtagtgt ccacagcaga
    63121 caaacgaatt cagagtcgga atgcaatcca taagcatatc tgcggatgca gatataagaa
    63181 agaaaggtga ttcctgtttc cgcccatgag cctgtcacca gagaaaagac tagaacgacc
    63241 gctagttttc caagattatt caataaaact tctaagacaa attttacttg gacatacacc
    63301 atatcttctt ccgatttgtc tccgctgaat aaggcttcta ataatttgtt cacaacttta
    63361 tctttcatct catacgtacc tccaccacaa attttatgct aaaaaaaata aaaaacgtct
    63421 tttgtttcat aaaaagtggt tttgacatca aaaccgtcat gatctcctaa aaaaatcttc
    63481 gttttccaag aaccttacca aaaaaagtga cagttttgat acgaaaagta ctttttatga
    63541 caagtttgtg ctttttcgag tgatttatgt taaaaaatta ctgaccttat aaaaggtgat
    63601 ggagggattc ttatggaaaa tgaacaattg tttgaagtcg gcgaaacata tgcatttaaa
    63661 tctgatttat ttgaatcacc aataaaagga aaaatagaaa aaatctatga aaatagtgtg
    63721 atgatacgtg tcatgaaatg cgcagtagaa gacaatgata ccgctcataa tctgcactgg
    63781 cagttagttg tacgcaaatc aagtacaata gaagaataaa aacagataaa atgttgagag
    63841 cataaagagg ttgtgagtct cccgtttagc tctgagttac aaggaataat gttaaaaaac
    63901 agcttttcat gttttatgaa tattgccttg tgaccgaggt gttggcagga gaatactgtt
    63961 tatttgaaaa aagggctgcg acaagacttt tgtcacagcc tttattttca tgaataggag
    64021 ttacttttgg ctacttttag agaagtagct tttaaggagc agataaagtc aaggctttta
    64081 tttctataaa tgaagtagta aaatgaagaa cagattttat tacaggaagg atgccgataa
    64141 ttgtgatcat tgttgcagga acgatcggtg cagggaaaag cacactaact gaaatgcttg
    64201 cccaagattt agaaacaaaa cctttttatg agaacgtgga agataatgaa gtattgccgc
    64261 tattttattc taatccagaa aagtatactt ttttattaca gattttcttt ttgaacaaac
    64321 gctttttggc aatcaaagat gctttcagcc atgatgacaa cgtactagac cgctccatct
    64381 acgaagatag tatgctgttt catttgaatg cagatttagg gcgtgtttct gaagtagaag
    64441 taaagcagta tgaaggtctt ttagaaacga tgctgaagga gttagaagaa atttcgccac
    64501 aaaagaaacc agatctactg gtttatattc gtgtatcctt tgaaactatg ttagcgagaa
    64561 tcaaaaaaag aggccgggaa tatgaacagc tagaacaaga tcctgaactc tattcctact
    64621 ataaagaact caatcgacga tacgaagagt ggtatgaaca gtttgatata tgtcccaaaa
    64681 tagtgatcga tggggacaaa tatgatttcg tagccgatcc ggcatgtgga gaacaaatcg
    64741 tacaagaaat caagatgcgg gcaaagaaaa tgacagaaga ggcagatgcc cagtcgatcc
    64801 gctacactac aaataacccg aaagcaaagg gaatctttac aactaaataa tataaaaact
    64861 aagcaaattg ctcactcgca gatatttctc tgtgagcagc atcttgctta gtttttttga
    64921 ttcattgaga tcaaatagtg aaccgattcg tatgataaaa ttgccataaa tgaaatgtct
    64981 gagtgagggc catgatcaaa aataaaatgg aaacgatcaa aatcgaatgg gcgccaaaca
    65041 gatgatgaca gaaaacaagg acaatagctc ctgcgataaa ggcaagaacg acacttagat
    65101 agtggaaaaa tcgatcaaaa tctgcttttt ctttagaaat acaataatca tataagttcg
    65161 ttgctacccc ttttaaattt ccagttgtaa ataaattagt gtaggcacgc ccgttgattt
    65221 tatcaaaagc tacccactgg atcgatgcag taaaagcaat caaaatcgtt actaatgcgg
    65281 gatgctcatg gacgggtgtc aaactaacaa agaaaaaaat cactgcttca taatatagaa
    65341 caaacaagcg ccagaaatgt ttttcttttt ttctaaaata atcaattaga tactttgtta
    65401 gaagaatccc taagaaaaag aaaagggtag acaatacttt tttaccaaca cttagccatt
    65461 ctccgtcaaa tgcttggatg atcgatagaa tgatattgcc agtttgagca gaggcaaaag
    65521 caccatattg gatataagta taactgtcca tggctcctcc gataaatgtc agcaaaagtc
    65581 ctattgtacg cccctcgtga aaggaagtct gcattttttt catcaccttt tatgaatatt
    65641 tttgtcttcc ttatcttagc ataaacgatt gaaaaaaagg aaaaattttc agaaaactaa
    65701 aatcatatcg cttcccattt tcatttttag aaaggtctgt tagtataaag aaaaaataga
    65761 caacgaaact ttaaataacc aacttgaaat aaacaaattc aaagaagaaa gatgggaagg
    65821 aaatcaatca gttgaatgaa aaagaaattc tccgattaca aaaagaattg aaacgctggg
    65881 agaacaagta taaaaagctt caacaagtct ttcggctaca agaagaaatc attgctacct
    65941 atgaagcggc ttatggcgaa gcacccggac ttattgagga agaagtacaa gtaaaagaaa
    66001 gtgaaggaaa cagctctttc tttaaaatga tggagaaacg ttcctataat cgcttcaatc
    66061 aagaacaaaa agcagctatc acatatgata tgaagaaaca tcttcgaatc atagcaggag
    66121 ctgggagcgg caaaacgcaa acaatctgtg caaaagctgt ttatctgatg acgcaaaaac
    66181 aagtagacga agaacgcata ctaatgatca cttttacaag gaacgctgca aatgaactaa
    66241 aaaaacgagt agataatttc agccagagaa aaaccgctgt ccatatcgga acattccata
    66301 gtatcttttt taggatatac aatgaaattt gtcgaaaatt tcctgaagta gcaatgcaag
    66361 gaatacaagg agacttttca aaggatactg cacaaaaagt gaatgctgtt ttgcaacagc
    66421 tgatacgtaa atataatctt tatatatttg atcaatatgg agaaaaaacg attgcttctc
    66481 ggttagacta ttggcagaat atgaaccttt cagtagaaga aatggttcag ttagttaaag
    66541 aaaaatatga ttccattgat aagaatgcac gacagccgat atcagaacga ctgtatggat
    66601 tgctcacgga actccaagaa caaaaaagaa gccagcaatt gctagagttc aatgatgtac
    66661 tccaaaatct gaaaagcgct ttggagaatg aggagatcca gcattatatc ggccaaaaat
    66721 atgattatct attcattgat gaatttcaag atactaatcc acttcaatgg gaaatcgtga
    66781 aacggatgac aaaggaaaac aggatcaagt tgattgttgt tggagatgat gatcagagta
    66841 tctatggatt cagaggatca gagccagcat acatcaagaa ctttgaaaaa gaatatccta
    66901 ccaaaactct tttcttatta actaattatc gttctcgggc agctattgtc caaggagcaa
    66961 atagattgat cagctataat aaaaatgatc ggataccaaa ggcgatgatt ccagcacaaa
    67021 aagaagcagg tgttatggaa gcctatttgt tttctgatac taaagcagaa agtcagtggc
    67081 taatcaaaca aattcagaca tttattcaaa aaaatgggaa atataaggaa tcaatcatat
    67141 tataccgatc agcttcacaa acgcagcagc ttgtccaatc tctgctgaaa acgaatattc
    67201 cttttgtact ggaagcagat agtccatatg aaggtatctt tggtatcaag tctttccaac
    67261 atttctatca aaaaattgtt cattggcaaa cagcactgaa tctgcaaaag aaaaatcagg
    67321 cctaccagca attgctccgg cagctgatgg cagactgcta cctgaaaaaa agtgaatgcg
    67381 atcaatactt ttctcctaaa tatcaaaata tagccgttgc agattatatt ttgtcgataa
    67441 gccccaattt aaaatcgaaa tctgcagaaa tccgagagtt tgaggaagcg ttgcgtaaaa
    67501 cagaccagca tcaagaaatc tattcgcttg ttcaaagcta tcttcatctg ccacgtatag
    67561 ctaaggaaat cgaccagagt gatcaagaat ggatacgaga agaagtaaag cagcatgcta
    67621 ctttcagaag actccaagcc ttatcgcaag aaacccaagc gacagctaaa gaattaaaaa
    67681 cccgcttgat tgcttacaga caaggaaaac ttgatgcact atgtatccag agcattcaca
    67741 aaagtaaagg tcttagttac cgaaatgtct ttttgattgg ttgtaacgaa ggaagtttgc
    67801 cttataacgg agcgacagaa aagaaagtaa tcgactttaa tgaaataaaa gcagaaccag
    67861 taacgacgat agaagaagaa cgaagactat tttatgttgc gatgactaga gcaagaaatc
    67921 gtctgtatct atgtgtacct caaatgaaaa attcaagaaa attgaaagta tcgagattta
    67981 tcaaagaaac cgggagtcgt gtgaaaaaag gaaagtgata gaagagaggg tgtgacagaa
    68041 gtggtcagtt tcaagaaaga agaaggaatg tacgaaaatt gcttctcaaa tttttgtgaa
    68101 atttcagctt attttcgaag aagctatttc tggaacacag tttattcgga aaagggaggt
    68161 gtgacaagaa ttttgtcaca cctcccttat ttattttgaa aatgagaata ctattatcaa
    68221 aatagagaat atatagaaaa attctcatta ttcaaacgta aataatcagt tattttgatt
    68281 tt
//
LOCUS       DACDAF010000003        68229 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.003, whole genome shotgun sequence.
ACCESSION   DACDAF010000003 DACDAF010000000
VERSION     DACDAF010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.003"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            352..1041
                     /locus_tag="IVZ69_000144"
     CDS             352..1041
                     /locus_tag="IVZ69_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8182265.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1028..2236
                     /locus_tag="IVZ69_000145"
     CDS             1028..2236
                     /locus_tag="IVZ69_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP8182266.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2530..3801
                     /gene="serS"
                     /locus_tag="IVZ69_000146"
     CDS             2530..3801
                     /gene="serS"
                     /locus_tag="IVZ69_000146"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HAP8182267.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="IVZ69_000147"
     CDS             complement(4350..5834)
                     /gene="guaB"
                     /locus_tag="IVZ69_000147"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HAP8182268.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6339..7034)
                     /locus_tag="IVZ69_000148"
     CDS             complement(6339..7034)
                     /locus_tag="IVZ69_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HAP8182269.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="IVZ69_000149"
     CDS             complement(7124..8224)
                     /gene="ychF"
                     /locus_tag="IVZ69_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HAP8182270.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8233..8424)
                     /locus_tag="IVZ69_000150"
     CDS             complement(8233..8424)
                     /locus_tag="IVZ69_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HAP8182271.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8445..9335)
                     /locus_tag="IVZ69_000151"
     CDS             complement(8445..9335)
                     /locus_tag="IVZ69_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HAP8182272.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9322..10089)
                     /locus_tag="IVZ69_000152"
     CDS             complement(9322..10089)
                     /locus_tag="IVZ69_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP8182273.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="IVZ69_000153"
     CDS             complement(10101..10814)
                     /gene="rsmG"
                     /locus_tag="IVZ69_000153"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HAP8182274.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="IVZ69_000154"
     CDS             complement(11046..12947)
                     /gene="mnmG"
                     /locus_tag="IVZ69_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HAP8182275.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="IVZ69_000155"
     CDS             complement(12964..14361)
                     /gene="mnmE"
                     /locus_tag="IVZ69_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HAP8182276.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14705..15043
                     /locus_tag="IVZ69_000156"
     CDS             14705..15043
                     /locus_tag="IVZ69_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182277.1"
                     /translation="MSPFRSAALEEESDPRINDVVLSTGNINQKYIVRDIVFVVECLE
                     ADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQKKRDGKYFLELFAYGT
                     VIQFIQTTIG"
     gene            complement(15211..15969)
                     /locus_tag="IVZ69_000157"
     CDS             complement(15211..15969)
                     /locus_tag="IVZ69_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP8182278.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(15987..16805)
                     /locus_tag="IVZ69_000158"
     CDS             complement(15987..16805)
                     /locus_tag="IVZ69_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP8182279.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="IVZ69_000159"
     CDS             complement(16802..17158)
                     /gene="rnpA"
                     /locus_tag="IVZ69_000159"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HAP8182280.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="IVZ69_000160"
     CDS             complement(17276..17410)
                     /gene="rpmH"
                     /locus_tag="IVZ69_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HAP8182281.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            17933..19267
                     /gene="dnaA"
                     /locus_tag="IVZ69_000161"
     CDS             17933..19267
                     /gene="dnaA"
                     /locus_tag="IVZ69_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HAP8182282.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19465..20595
                     /gene="dnaN"
                     /locus_tag="IVZ69_000162"
     CDS             19465..20595
                     /gene="dnaN"
                     /locus_tag="IVZ69_000162"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HAP8182283.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            20824..21066
                     /gene="yaaA"
                     /locus_tag="IVZ69_000163"
     CDS             20824..21066
                     /gene="yaaA"
                     /locus_tag="IVZ69_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HAP8182284.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21053..22177
                     /gene="recF"
                     /locus_tag="IVZ69_000164"
     CDS             21053..22177
                     /gene="recF"
                     /locus_tag="IVZ69_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HAP8182285.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22174..24120
                     /gene="gyrB"
                     /locus_tag="IVZ69_000165"
     CDS             22174..24120
                     /gene="gyrB"
                     /locus_tag="IVZ69_000165"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HAP8182286.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24140..26611
                     /gene="gyrA"
                     /locus_tag="IVZ69_000166"
     CDS             24140..26611
                     /gene="gyrA"
                     /locus_tag="IVZ69_000166"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HAP8182287.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            26847..27146
                     /locus_tag="IVZ69_000167"
     CDS             26847..27146
                     /locus_tag="IVZ69_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HAP8182288.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27196..27708
                     /gene="ssb"
                     /locus_tag="IVZ69_000168"
     CDS             27196..27708
                     /gene="ssb"
                     /locus_tag="IVZ69_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP8182289.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            27734..27970
                     /gene="rpsR"
                     /locus_tag="IVZ69_000169"
     CDS             27734..27970
                     /gene="rpsR"
                     /locus_tag="IVZ69_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HAP8182290.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28113..30086
                     /locus_tag="IVZ69_000170"
     CDS             28113..30086
                     /locus_tag="IVZ69_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HAP8182291.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30092..30544
                     /gene="rplI"
                     /locus_tag="IVZ69_000171"
     CDS             30092..30544
                     /gene="rplI"
                     /locus_tag="IVZ69_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HAP8182292.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            30818..32185
                     /gene="dnaB"
                     /locus_tag="IVZ69_000172"
     CDS             30818..32185
                     /gene="dnaB"
                     /locus_tag="IVZ69_000172"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HAP8182293.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            32965..34257
                     /locus_tag="IVZ69_000173"
     CDS             32965..34257
                     /locus_tag="IVZ69_000173"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HAP8182294.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            34993..35856
                     /locus_tag="IVZ69_000174"
     CDS             34993..35856
                     /locus_tag="IVZ69_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP8182295.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(35985..37607)
                     /locus_tag="IVZ69_000175"
     CDS             complement(35985..37607)
                     /locus_tag="IVZ69_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8182296.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            37856..38377
                     /locus_tag="IVZ69_000176"
     CDS             37856..38377
                     /locus_tag="IVZ69_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182297.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38563..40293)
                     /gene="spxB"
                     /locus_tag="IVZ69_000177"
     CDS             complement(38563..40293)
                     /gene="spxB"
                     /locus_tag="IVZ69_000177"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HAP8182298.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40458..41276
                     /locus_tag="IVZ69_000178"
     CDS             40458..41276
                     /locus_tag="IVZ69_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HAP8182299.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41379..41576)
                     /locus_tag="IVZ69_000179"
     CDS             complement(41379..41576)
                     /locus_tag="IVZ69_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182300.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            41745..42323
                     /locus_tag="IVZ69_000180"
     CDS             41745..42323
                     /locus_tag="IVZ69_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP8182301.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            complement(43368..43871)
                     /locus_tag="IVZ69_000181"
     CDS             complement(43368..43871)
                     /locus_tag="IVZ69_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP8182302.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44230..45255
                     /locus_tag="IVZ69_000182"
     CDS             44230..45255
                     /locus_tag="IVZ69_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP8182303.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45578..46456
                     /locus_tag="IVZ69_000183"
     CDS             45578..46456
                     /locus_tag="IVZ69_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182304.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            46932..47048
                     /locus_tag="IVZ69_000184"
     CDS             46932..47048
                     /locus_tag="IVZ69_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HAP8182305.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            47976..48314
                     /locus_tag="IVZ69_000185"
     CDS             47976..48314
                     /locus_tag="IVZ69_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182306.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            48408..48638
                     /locus_tag="IVZ69_000186"
     CDS             48408..48638
                     /locus_tag="IVZ69_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182307.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            49038..49409
                     /locus_tag="IVZ69_000187"
     CDS             49038..49409
                     /locus_tag="IVZ69_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HAP8182308.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(49683..50375)
                     /locus_tag="IVZ69_000188"
     CDS             complement(49683..50375)
                     /locus_tag="IVZ69_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP8182309.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(50378..51163)
                     /locus_tag="IVZ69_000189"
     CDS             complement(50378..51163)
                     /locus_tag="IVZ69_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP8182310.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            51400..52800
                     /gene="lacG"
                     /locus_tag="IVZ69_000190"
     CDS             51400..52800
                     /gene="lacG"
                     /locus_tag="IVZ69_000190"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAP8182311.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            52825..53142
                     /locus_tag="IVZ69_000191"
     CDS             52825..53142
                     /locus_tag="IVZ69_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP8182312.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            53155..54828
                     /locus_tag="IVZ69_000192"
     CDS             53155..54828
                     /locus_tag="IVZ69_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8182313.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            54842..56473
                     /locus_tag="IVZ69_000193"
     CDS             54842..56473
                     /locus_tag="IVZ69_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinogalactan endo-1,4-beta-galactosidase"
                     /protein_id="HAP8182314.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            57345..58535
                     /locus_tag="IVZ69_000194"
     CDS             57345..58535
                     /locus_tag="IVZ69_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HAP8182315.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            58669..60858
                     /locus_tag="IVZ69_000195"
     CDS             58669..60858
                     /locus_tag="IVZ69_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP8182316.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            60855..62648
                     /locus_tag="IVZ69_000196"
     CDS             60855..62648
                     /locus_tag="IVZ69_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP8182317.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            62848..63162
                     /locus_tag="IVZ69_000197"
     CDS             62848..63162
                     /locus_tag="IVZ69_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018705633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP8182318.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            63183..63560
                     /locus_tag="IVZ69_000198"
     CDS             63183..63560
                     /locus_tag="IVZ69_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP8182319.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            63570..64343
                     /locus_tag="IVZ69_000199"
     CDS             63570..64343
                     /locus_tag="IVZ69_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182320.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            64365..65768
                     /locus_tag="IVZ69_000200"
     CDS             64365..65768
                     /locus_tag="IVZ69_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HAP8182321.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            65950..67134
                     /locus_tag="IVZ69_000201"
     CDS             65950..67134
                     /locus_tag="IVZ69_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP8182322.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            67131..67421
                     /locus_tag="IVZ69_000202"
     CDS             67131..67421
                     /locus_tag="IVZ69_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182323.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            67418..67639
                     /locus_tag="IVZ69_000203"
     CDS             67418..67639
                     /locus_tag="IVZ69_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182324.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            67681..>68229
                     /locus_tag="IVZ69_000204"
     CDS             67681..>68229
                     /locus_tag="IVZ69_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182325.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLY"
BASE COUNT        21465 a        12288 c        13467 g        21009 t
ORIGIN      
        1 tttccaacat gtcaacaact tattttttat tatttaataa gttattggtg ttcttttgaa
       61 caaataataa tatatcaaca tcacatgtga aagtcaataa gaaaatgctt atttatcaac
      121 atttctagct tacatgatca ttggttagtt ctggtccttt ttcgttcgtc tttataactc
      181 cgagagacgt aaaatccttt tgttttcagt ttaatgttca tgttcttgtc ttattcacac
      241 caactagatg tctcaccttc taaaattttc cttaacaaag tgctgctttt atctatttct
      301 gctttttttt gctagaataa tagtaacaat atgactctgg aggatttatt tatgaaaatt
      361 ttgattgctg acgatgataa agaaatcgtt gaattattaa gtatctatgt tcacaatgag
      421 gggtatgaag cagtaaaggc ttatgatggg aaagaagcat tatctaaaat cagaacaatc
      481 cctgatattg aattacttat tttagatatc atgatgcctg agatggatgg gatgcaagta
      541 gtgaaagagc tacgaaaaga atcccaaata ccaatcatta tgctgacagc aaaaactact
      601 gatatggata agatcaaagg actggtcgct ggtgcagatg attatgtgac caagccattt
      661 aatccgttag aagtaatggc tagagtaaag tctttattac ggcgtacaaa aatgcagatt
      721 gccccagatc agcctgatgt attagaagta aatgcattaa tcatcaataa agactctcat
      781 gaagttaaaa caatcgatgg gaaagaaatc cagttaacag ctttggaatt cggtatcctc
      841 tacttgcttg ctagtcatcc taatcgagta tttagcgcgg atgaaatttt tgagcgtgtt
      901 tggaaacaag aaagtattgt ctctgctaaa actgtcatgg ttcacgttag tcatttaaga
      961 gataagattg aagaagcaac tggtggtgaa aaagtcattc aaaccgtttg gggagtgggc
     1021 tataaaattg acgcaagata gtaaacgagc aactgaaaaa cgccgtcgga tcaatttgac
     1081 ttcaaaagaa atcagcgaat tgttagcgga aggaatcatc acgattatcc ttttgcttct
     1141 attaaatgtt tctattctgg ttgttatcag ttcggtgatc aacagttcac cttctttgac
     1201 gaatgcgatt tgggattcaa agaatatttt tgcagaacga ttgaacactg atttgttctg
     1261 gaacggccgg aattttatta ttcccttttt ctttctatta gatattggtg ttttgtattg
     1321 gcgcttgatt cgaagatatc gccaaatgca attgcggcat atcatcagcg aacttcacta
     1381 catcgcaaac ggaaattatg atcatcgtat cccttttgaa ctgagtggtg acttaagccg
     1441 agtggtaaca agtatcaatg gattggtgga tagtaccgta gcagcgattg aagacgaacg
     1501 taaaatcgaa aaatcaaaag atgaattgat cacgaatgtc agtcatgata tccgtacccc
     1561 actcacgtcc atcattggat acctaggact gatagaagat ggccagtatc actcagaaga
     1621 agatctttta aagtatacgc atactgctta tatcaaagca aagcagatga aatctttagt
     1681 ggacgactta tttgaataca ctaaggtacg ccagcctgct gtcccggtga atttttctgc
     1741 ctttgacatg atccagttga tcgaacagtt agcagctgat tttgagttgg aagcttctaa
     1801 aaaaaatatc caaatacttg ttcaatcaaa agtagactcc cttatcatgg atggcgatac
     1861 cgaaaaactt gtacgtgtct tcaataatct tttgacgaat gcgttgaaat acggaaaagg
     1921 agcaacgaag atcgtaatcg aagtagaacg tatcggttca gaagttgttg caacagtcaa
     1981 aaataacgga gcaatgatcc cacaacaggc aatcgataat ctattcgacc gtttttatcg
     2041 tgtagaagaa tctcgttcac aagcaactgg aggaactgga cttggtttag caatcgctca
     2101 aagcattgtg gctttgcacg gcggatacat ttatgcaaaa tcagataagc aatggacttc
     2161 tttcatcatg caccttccaa tcaagaaaaa tgaaaaatta cctattgata cacaggaagt
     2221 tattgacgaa agctgaaata ttcgctattc ttattacaat tattagaata aatgaaaaac
     2281 acagaaccca gtacacttta ttctttttca gagagctgat ggcaggtgta aatcagcaaa
     2341 ggataatttg gaagttccag ttcgtttacg tgccctttcg aaataagaaa ggtcggttca
     2401 acagccgtta tgtgttcaac aagtgcagct gacgctgaac ttgggtggta ccgcgaattt
     2461 cagactgatt cgtcccaaga ataatgggat ggatcagtct ttttttattt tcaaaaagga
     2521 ggaaatcata tgttagatgt aaaaatgatg cgacaaaata ttgaagaagt acaagaaaaa
     2581 ttgatgactc ggggcgtaaa aaaagaaaca ttagctgaat tcatggaact agatgaaaat
     2641 cgtcgtaagc tactagtcaa aagtgaagaa ttaaaaaaat atcgaaatga tgtttctgct
     2701 gagatcgccc aattgaagcg tgcaaaagaa gatgcttctg ctaaaatcgc tgaaatgaaa
     2761 gaagtcggtg gcaacatcaa agcattggat actgaaattg ctgaagtgga tgaaaaattg
     2821 aaacaaattg caactacttt gccaaacctt ccccatgatt ctgtgccagt tggaacagat
     2881 gaagaggaca atgtagaaat ccgtcgttgg agcgaaccac gtacatttgc ttttgaacca
     2941 aaaccacact gggaaattgc agaaaatctt gatattttag attttgaacg tggcgcaaaa
     3001 gtagccggta gccgttttgt ctattacaaa ggattaggtg ctcgattaga acgtgctgtc
     3061 tacaacttca tgcttgatca gcatatttac gaacacggct atactgaaat gatcactcct
     3121 tatatcgtca acagtaaagc gatgtttggt acgggacaat ttccaaaatt caaagaagat
     3181 gttttccaat tggagaatac tgatctaaca ttaatcccaa cagctgaagt accattaact
     3241 aactattata atgatgaaat tttagatggt gcagatttac ctatttattt cactgcacta
     3301 agccctgctt ttcgttctga agccggaagt gctggtcggg atacacgagg actgattcgt
     3361 cttcaccaat tcaataaagt agaaatggtc aaattttcgg atgtagagca ttcttacgaa
     3421 gaattggaaa aaatgacagc tgatgcagaa gatatcttga aaaaattgca tttgccttat
     3481 cgtgtgatgg ccttatcaac tggagacatg ggcttttctg cagctaaaac ttatgactta
     3541 gaagtatgga tacctgcaca agatacttat cgtgaaatca gttcttgttc taactgtgaa
     3601 gatttccaag cacgccgcgc aatgatccgt tatcgcgata atgatggaaa aatccactat
     3661 actcatactc tgaatggttc aggacttgca gttggccgta cagtagctgc cattttggaa
     3721 aactaccaaa atgaagatgg ttctgtcaca gttccagaag cgctcgttcc ttatatgggg
     3781 aatctgaaag ttattaaata aagaggctgt gaaaaagccg cttagtttcg agtattaaga
     3841 aaaattttgt gaaaatggct ttccacattt ttgcataaat tggacttaat accgagaaac
     3901 tggcttttga acaccattta tcgagaggtt gtgaaatcag cgaattaacc tgagtattag
     3961 agaaaaaaat ggaaaaatag tccctcatat tttaccgttt gttgaactaa taccgagggt
     4021 cagctgattg aacaccgttt agtggagagg tcgtaagcct accccccagc tcctagttac
     4081 aaggacaaat tcaaaaaaca gctcttcata ttttatgaat gttgtacttg tgattcggag
     4141 gtggcaaggg aacactgttt attcaaaaag aggctgggac agaagcgttt aactccaaga
     4201 aataagaaga aattcacgaa aattgctttt caaatttttg tgaatttctt cttatttccg
     4261 aaggagttgc ttctacttcc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
     4321 ttacttttgt cccacgctct ttaatgtttt taagattcaa ctgaatagtt tggtgcttct
     4381 tttgtgattt gtacatcatg agggtgtgat tcttttaatc cactgccgct catttggata
     4441 aattgcgctt catcacgtaa ttgctgtaga ttggctgccc caacataacc cattcctgaa
     4501 cgcaaaccgc cgatcatttg gaaaataata tctgcaacac ttcctttata agcaacccga
     4561 ccttcgattc cttctggtac taatttattt gcttcattga cactaccttg gaagtaacgg
     4621 tcttttgaac ctttttccat cgcgcctaat gagcccatac ctcggtatgt tttgaatcga
     4681 cgtccttgga agatttcgaa ttcacctggt gattcatctg tccctgccaa catacttcct
     4741 agcatcactg catgtccgcc ggcagctaat gctttgacga tgtcaccaga atatttgatc
     4801 cctccgtctg caataatcgc tttgccatat tgacgagcaa ctgatgctgc atcataaata
     4861 gctgtgagct gaggtacacc tacaccggct accacacgtg tcgtacaaat cgatcctggt
     4921 ccgataccaa cttttacgac atctacacct gcatcatata aagcttttgt cgcttcagcc
     4981 gtcgcaacgt ttcctgcaat caatgttgca tctgcaaaag ttgaacggat ttcttgaatt
     5041 tttcggatca cacctgcact atgtccatga gctgtatcga tgatgattgc atctgcccct
     5101 gcttctaata aagcattcgc acgctcaaat gtatcgcttg ttacaccaac ggctgctgct
     5161 acaagcaatc gaccatgttc atcttttgct gcatttggaa attcgatcac tttctcgatg
     5221 tctttgatcg tgatcaatcc gcttaaacga ccttcgttat ctacgattgg taatttttcg
     5281 attttatgtt tttgcaaaat cttttctgca tcttttagag aggtacctac tggggcagtc
     5341 actaagttgt cttttgtcat cacatcagca atcggcatgt gataatctgt tacaaaacgc
     5401 atgtcgcggt ttgtaattat ccctaccaat tttctgtttt caagtgtttc aacgattggc
     5461 acaccactga tacgatattt gctcatcaat tcttctgcgt ctgctacaag atgctgtggc
     5521 gttaagaaga acggatcaat gattacgcca ctttcagaac gtttgacttt tcttacttca
     5581 tccgcttgct ggctgatcgt catgttttta tggatcacac ctagtccgcc ttgtcttgcc
     5641 atagcaatgg ccatcttgct gtcggtaaca gtatccatac ttgcactgat gattggaata
     5701 ttcaacttaa tatttttagc taattgtacg ctcatatcca cttcgtttgg taacacgtga
     5761 ctttctgctg gtatcaataa gacatcatca aaagtaaatc cttttttcgt gaactttgtt
     5821 tcccagttgg acatttttag taccactcct ctaatttagt ttatctatta aaataattga
     5881 ttttttcatt taagtcaatg atctacttgg aatcaagtta gctttctcat agaataccaa
     5941 tataaagcgt ttacatctgt gtatattaaa agagattgta aaaaagctgt cctgcatcaa
     6001 gtaataagaa cagccaatca aaaacagctt ctcatgtttt tgaattggtt gggtttatta
     6061 ccgcagatgc aaacttttga acaccgttta gtggagaggc tgtgaaaaag ctgcttagtt
     6121 tcgagtagta agaaaaattt tgtgaaaatg gctttccaca tttttgcata aattggactt
     6181 aataccgaga aactggcttt tgaacaccgt ttatcgtaaa aagggactgt gacaagactt
     6241 ttgtcacagt cccttactat tatttaacta tggataaaca aaatgaggtt ctttactacc
     6301 cctagatatc tagcaaaata gctgatcttt ttgctagttt atcttcttgg gacggataaa
     6361 cttccaataa tcccgtattt tttcttcaag tagtaacgga ttgctaaagc agttgccccg
     6421 ataatgataa ctactactgg atctaatact ggattgataa ctggtggcaa tagtgttgtc
     6481 gcagaaaaca gtacgaccca aagaagtgtc gttccaccta ggataagcaa tgtcttaccc
     6541 attcctggtt tcttgcttcg atctgctccg ggatattcat attgatagat gtatttgtac
     6601 atcatataaa agacccagcc accgattgca gaacctagaa cgagtgtaga aaagccataa
     6661 gctggcgttg ttccacgtga aaacaatccg gtaatcgcaa tcatgatact taatagacca
     6721 agcaacagca acgtattatc taaccacatc aataaagggg tggatgaatt ttttacttct
     6781 gctggcttat tgatgattgc ttccgttctt tcagagactg tcccaaacaa ttgacgggct
     6841 gttcttccgc ctttttgttc tgcaactaaa gtaggcagaa tgtcatgaag ggcttttact
     6901 ttttcttctt cagacaaatt cgctgcttct aaagattttt tcaaatcaaa aatgtactgt
     6961 tgatttcttt tggttaattt tgtttctaaa ctattgtttt cttttacgat tgctcgtaat
     7021 tgttctggtt ccattatcta atagtcctcc ttagccgttc cttttctcaa cggtcgtcac
     7081 aaaagacatt ctaccatatt ctacagctag tttgatagcc cttttacaca ttaaagcgga
     7141 ataacattac gtcgccgtct tgtacgacat aatcttttcc ttctaatcga acacgtccag
     7201 cttcttttgc tgcatgcatg tttccgtaat gatccaagtc ttcaaaagag acagtttctg
     7261 cacggataaa tccgcgttcg aaatctgaat ggatgattcc tgctgcttgt ggtgctttga
     7321 ttcctttttt gaatgtccaa gcacgtactt cttgttcccc agcagtaaag taagtagcta
     7381 agcctaacaa atcataagca gcacggatca actgatccaa acctgattct tcgattccta
     7441 aagcttctaa aaattccgct ttgtcttctt catctaattc tgcgatttct tcttctgcac
     7501 gagcactgac cacgatcact tctgcatttt cttctgcagc aaagttgcgc acttcttgta
     7561 cataatgatt cgcgtctgca tctgctacgt catcttctga gacattggct acataaagaa
     7621 ttggttttgt cgtcaataaa aatagtgatt taacgatttt ttgttcttct tcagtaaatt
     7681 cgatcgttcg ggcagatttt ccttcttcca gtacaggttt gattttatcc agtacagcta
     7741 gttctgccac tgcatcttta tctttggttt tagcaacttt tgctacacga gtatagcgtt
     7801 tgttgataga ttctaagtct gctaacacta gttccaagtt gatcgtatca atatcttcta
     7861 gtggatcaac acgtccttct acgtgagtaa tattatcatc atcaaaacag cgaacaacgt
     7921 gacaaatagc gtctacttgg cggatatggc ttaagaattg atttcccaaa ccttctcctt
     7981 tacttgcgcc ttttacgatt ccagcaatat ctgtaaattc aaaagtcgtc ggaacagttt
     8041 ttttcggatg tacaagttct gttaagcgtt gcaaacgcca gtcaggtact tctaccatcc
     8101 ctacgttggg gtcgatcgtc gcaaagggat agtttgctgc ttctgctcct gcttttgtga
     8161 tcgcattaaa caaagttgat tttcctacgt tgggcaaccc aacaattcca gcagtcaatg
     8221 ccataaattt attcactctt tctctgcatt tttttcaatt acttttttta atttcttttc
     8281 aaaatctcga cgggtcatca tgacgatatg tccgcaattc atacatctga ttttgatatc
     8341 tgcgcccatt cgaatgactt cccagcgatt cgtctggcaa gcgtgaggtt ttttcatttc
     8401 aacgatatcg tgcaagtcgt acataaaaat agcctccttt ttgtttattc ttcatcaaat
     8461 tgaatattca agatatcaag aattcgagtc aaatcttttt gagaaagata ttcaatctcg
     8521 atcttacctt tcccattttt ttcttggata gctacacttg taccaaattt atccatcaaa
     8581 cgatcttcgc tttctcggat ataatatggt ttttcctttg ctagccttgg gatttttttc
     8641 ttttcttttc catcattttg atttaactca gaaacaagct gttccagttg gcggacagtt
     8701 aaattttcag ttactgcacg attggctaat ttcaagatca atgttttatt ttttaaacct
     8761 aacagcgtac gggcttgtcc catagataaa cgctgatctt gtaccatttc cttgacaaga
     8821 tccggtaaag aaagcaagcg caaataattg gcgatataag gtctgctctt tcctaaacga
     8881 ctagctactt ctgcttgtgt tagtttcagg tttttcatca gcatctcata tgcttctgct
     8941 tcttctaacg gattcagatc ttctcgctgc aagttttcca gcactgctac ttgcatcatc
     9001 gcttcttcgt caaagtctct aacgatagca gggatcgttt ctttttcagc tagtttggac
     9061 gctcgaaaac gtcgctcccc tgcaataatc tcatatcctt ttactgcgga acggcgtacg
     9121 atgatgggtt gaaagacacc tgattgttca atagaattag ctagttcctg caaagatact
     9181 tcttcaaatg ttttacgggg ctgatacgga tttggtcgca gctcattcaa tggtagctgg
     9241 acaacggtat catcttttac atccaccgtc tctaagtttt ctaaatcttg aaacagtgca
     9301 tcgattcctc ggcctaatcc tttacttttc ttcacgactt accacttcct ttgccaatgc
     9361 ttggtagact tcagctcctc gagaacgtgg atcgtagtcg atgatcggtt ttccatgact
     9421 aggtgcttct gataaacgaa tatttcttgg aatgatcgtt tcgtaaactt tttcgcggaa
     9481 gtatttacgt acttcttcta cgacttcatt tcccagattt gttcgtgcat catacattgt
     9541 cagtaagact ccctcgatct ctaattctgg attaaagtgt ttttggacta aacgaaccgt
     9601 attcagtaat tggcttaatc cttccaatgc gtaatactca cactgaacag gtatcaaaat
     9661 cgaatcactt gctgtaaatg aattgattgt cagatggcca agagaaggcg ggcaatcgat
     9721 caaaatataa tcatactgac tgcttacttc tgctaaagat ccttttaatc ttgattctct
     9781 tgccatcatt gacgtcaatt cgatctctgc tcctgctaat tggagagtcg caggcacaat
     9841 actcaaattt tcgtgttcag tgatcaaagt tgcctcatca attggcaatt cattgactag
     9901 aacatcatag atgtctcttg tcacatcagg ttttctgatc ccgacaccac tggtagcatt
     9961 tccttgtgca tccatatcca ctagcaatac ttttttgcca aggctagcaa gacaagcacc
    10021 tagattcacc gtcgtcgttg ttttgccgac gccacctttt tggttcgcaa cagatattat
    10081 ttgtgccatc tcttctcctc ctatttgatt ggctgcttat taggcagtcc gggctttctt
    10141 gggtatttct ttggggttgg tttctttttt tgaataacga tgatatgccg ttgatcagag
    10201 acattcggca aggtaaccgc ctcttctttg aggaatttac cacctaataa agcaatcgct
    10261 tgttttgctt ctgtcaattc ctcttcactt tttgctgctt tcaatgcata aaaatagcct
    10321 tcttgtttag ccaagggcaa acacaattcc gctaacacat tcaaacgagc aaccgcacga
    10381 gcagtgacaa ggtcaaatga tgcacgaaag tgaggatttt gcccaaatgt ttctgcccgg
    10441 tcatgatata aggaagcatc gattcctaat aatcgggtta actcagataa gaaggttatt
    10501 cgtttattca gagaatcaac gatcgttatc tgcagttctg gaaaggcaat ttttaaaggt
    10561 atgctaggaa accctgcccc cgaaccaaca tcgcataaag ataaaggttg cgtaaagtct
    10621 acttcaaatg ctaatgtaag tgaatcgtaa aaatgcttca gatatacgtc tttttcatcc
    10681 gtaatagctg taaggttcat cttttcgttc cattcgacta atgtccgata ataaatagcg
    10741 aattgattca tttgatgatc ggtaagctct atcccttttt ctgccaagga ttggcgaaat
    10801 tcttctggta tcataaatat tcctttcatt gtgaaacagc aattgtttca cagattctct
    10861 ccctacttta acgcaaaatc tctagacatg caatccttcc atatggattc ttaaaaattt
    10921 gaaaagtaag aaaagccgat agactttttc tttctagtat gactcataaa atatacacag
    10981 aagagagaac tagctttgag caatttctgc aaaaactagt tctctcttct atttattatt
    11041 acgtattacg ctggttcact gactttcgca atcttccctt gttcgatata gaccattagg
    11101 atacttaggt ctgcagggtt tacgccactg attcggctag cttgggcaat tgtttctggt
    11161 tggattttct gcaatttttg ttttgcttct gttgctaatc cgttgattgc tgcgtagtcg
    11221 atgttttctg gaatcttttt cgcttccatg cgttttaatt tttctacttt ttccatggct
    11281 tttttgatgt agccttcata tttgatttgg atttctactt gttcgatttc ttttcgtgtc
    11341 aattcttcat tttctggaat aaaccgtaga agttctgcat aagtaatctc aggacgtctt
    11401 aaaaagtcgc ttgctagtac accatctttt aatggtgccg cattaatcgt tgctaaaaag
    11461 tcttggactt cttctgttgg tttgattcgt acattcatca aacgtttgat ttcttgttca
    11521 actgcttctt ttttcttcaa ataattcttg tattgatctt cttttactaa gcctacacgg
    11581 tgacccattt ctgttaatcg caaatctgca ttatcatgac gtaaaagcag acggtattca
    11641 gcacgtgaag tcagcaaacg ataaggttcg ttcgttcctt ttgttaccaa atcatcgatc
    11701 atgacaccga tgtaaccgtc acttcgtttg atcactaaag gttcttttcc ctgaactttc
    11761 aaagctgcat tgataccggc aatcagccct tgtccagccg cttcttcata accgcttgta
    11821 ccatttgttt gtccagctgt ataaagattt tcaacgactt tagtttctaa tgtcggacgg
    11881 agctggtgtg gctctactac gtcatattcg atagcatatc ctgtacgcat catttctact
    11941 ttttctaatc cagcaataga atgaagcatg ttgacttgaa catcctctgg taaagaagta
    12001 gataaacctt gaacatagac ttcttccgta tttaagcctt ctggttccaa aaataattga
    12061 tgacgtggtt tgtctgcaaa acgcacgatc ttatcttcga tggatggaca atagcgagcg
    12121 cctacccctt caacgatccc tgtaaacatt ggggcacgat gtaagttgtc tcgaataatt
    12181 tggtgagtcg tctcacctgt ataggtcagc cagcaagatt cctgatctag tttataggca
    12241 ctatctggtg tgctgaagct aaaatgattc ggctctttgt caccaggctg ctcttctgta
    12301 acagaatagt cgatcgtact tgattttact cgaggcggtg ttcctgtttt gaaccgttcg
    12361 atagcaaagc caagttcttt tagatgattc gctagtccaa tagaaggttg agagttattc
    12421 ggacctgatg aatatttcaa ttcaccgata atgatttctc cgcgaagtgc tgttccggct
    12481 gtaataacaa ctgctttggc ccggtagctc gctcctgtgg acgtcactac tccatgacaa
    12541 acaccatctt cgacgatcag ttcttcgacg attccttgtc ttagcgtcaa atttggttct
    12601 ttttcgatcg tatgtttcat ttctgttgaa taagcatgtt tgtctgcttg tgctcgcaat
    12661 gctcggacag ctgggccttt tcctgtgttc aacatacgca tttggatata ggttttatcg
    12721 atattcttac ccatttctcc gcctaacgca tcgatttctc gaacgacaac gcctttagct
    12781 ggtccgccta cagaaggatt acatggcatg aatgctacca tgtccaaatt tattgtcagt
    12841 aataatgttt ttgatcccat acgtgcagca gcaagtgcag cttctgaacc ggcgtgtcct
    12901 gcgccaacaa cgatcacgtc atacgcatct gcttcataat gttccaatcg tttgttcctc
    12961 cttttatttt cctaaacaaa attgactgaa taattgagtg attagctcat cttgtacact
    13021 gtcgccgaca acttctccta gatagtccca gcaacgcgtc atatctattt gaacgagatc
    13081 cacaggcatt cctgaatcaa tacctgcaat gacttcttca agtgagaggg aagctttttc
    13141 taacaacgcg atatggcggg tattagaaac ataagtagcg tctctttctc ctgtttctcc
    13201 gctgaagaat aaatcagaaa tagctgattc caaacgatct agtccgtcgt ttttagctac
    13261 ggaaattgaa aaaactggtt cattttcgat caatttcttc aatttttctt gttccagctg
    13321 tgctggcaaa tctgttttat ttagaagaat gatccgtttc aatccacttg tcgcttccaa
    13381 taattgttca tcttctgctg tcagtggttc gctttggttt agaacaagta agatcaagtc
    13441 tgcttctgct aatgcttttc ggcttctttc gaccccgatc cgttccacca catcttctgt
    13501 ttcccgaatt ccagctgtat cgattagctt gagcggtacc ccccgaacat tgacatactc
    13561 ttcgattaca tctcgagtcg ttcctgcaat atccgtaacg attgcttttt cttctcttaa
    13621 caaatggttt aacaaacttg atttgccgac atttggccgg ccgatgattg ccgtacttaa
    13681 cccttcccgc agaaccttcc cttgcttgga tgtagcaagt agcgcttgga ttctttgttg
    13741 gatcatctgc gctttttcaa gcaataactt cgtagtcaat tcttcgacat catcatattc
    13801 tggataatca atatttactt ctacttgtgc taatgtctct aaaatctctt gtctcaatga
    13861 gcggatcaaa gcagacagat tgccgtctaa ctgattaaga gctagtccca ttgctttgtc
    13921 tgtttttgcc cgaatcaaat ccatcacagc ttctgcctgt gaaaggtcaa cacgaccatt
    13981 caagaatgct cgttttgtga attcgcctgg ctcagctaat cttgcacctt ctcttaacaa
    14041 tagctgcaaa atttgattga ctacaacgat cccaccgtga caattgattt ctactacatc
    14101 ttcccgcgta aatgtctttg gtgctctcat cacggagacc atgacttcat cgacaagctg
    14161 attgctcttg ggatcaacga tatgtccata atggatcgta tgacttggta cttctgataa
    14221 tcgtttgttt ccagattgat aaactttatc tgctagttgc acagcttgat cgccacttaa
    14281 acgaacgata ctgattgcac cttctccagg tggggtagaa attgccgcaa tcgtatcaaa
    14341 ttctaaagta atttcagcca ttttttcact tcctttttca ttttgcgcac aaaaaaagtg
    14401 cccactccac cctttatgca caataaacgg tgaacttcgc actttgactg cttgttcttg
    14461 attaaattct ggtcatagat tatcacactt gctataagga atcaagtgtt taaaacaatt
    14521 agatgaagtt gagcctgttc tgcttccatt accttatatt taattgtcct tggatgtctc
    14581 tttgcgttct ttggtttatt cgaagagaag atactgtata aacaaggctt tatctttctt
    14641 aaaaaaaacg gtacactaaa tggtagcgct atctaaacta tacacttttg aaaggagaaa
    14701 atatgtgagc ccgttcagat ctgctgcatt ggaagaagaa agtgaccctc ggatcaacga
    14761 tgtcgtttta tctacaggga atatcaacca gaaatatatc gtccgcgata tcgtttttgt
    14821 tgtggaatgc ttagaagctg atttgtttga cccatctttt cccaaagatg accttttctt
    14881 aacaacgaag aggaaattaa agacgaaggt acttgaatat ggtgcgaatg cagtaatcaa
    14941 ctgtcatttt gagtatcagc aaaaaaaacg cgacggaaag tattttctgg aactttttgc
    15001 ttatggaaca gtgatccaat ttatccaaac aacgattggt taaatgaaac agacaaaaaa
    15061 agcggatcaa aactgaagac agtttcgatc cgcttttttc tatcaaagtt agtgactact
    15121 tcatcgtata ctctgataag aatgatttct agtaaaatat acttggtttg aaaaactttg
    15181 tcaacgtgat ttattcaaaa agtaatggaa tcaataatat tttttagcag gttctactac
    15241 taaataacga taaggttcct caccttccga atgtgttttt acatgttcat ctttgcttaa
    15301 tgcagcatgg atttgtttac gttcaaatgc aggcattggt tctaagaaaa caggctgccc
    15361 tgtccgtttt actttttcag ccgtgcgatc agctaaacgc tgaatgatct cttggcgctt
    15421 ttcacggtaa ttgcctacat tgactactac agacagctta tttcttgcta aacgatggat
    15481 gaagacttgt gccagatatt gcaatgcatt cagtgttttt ccatgtttcc caatcagtat
    15541 gccttgcttt tgtgtttcta aatggaaaac aaccatatta tttgattctc tttccatttt
    15601 gacaagagct ggagcatcaa gctgttttga aatttcagta agataaactg ccaattccgt
    15661 taaagctgct tcatcaccta gctcacttac ttcttctgtt ttttcttcaa gaatcgtttc
    15721 gttgactacc tcgatctcag ctgttggttc ttcttccaaa atttcttcta cagtctgttc
    15781 tactgtttca gaaacttttt cgctgatact tggctggatc gaaagccgtg cattctttcg
    15841 acccattcct aggaaacctt tttttccttc ttccagtatt tcgatttcga cttggtcttt
    15901 ggccaaaccc aaatcagcca gacctagttg gacagcttcg tctattgttg cagcttcata
    15961 aatcggcatt agcattacct cccctattat ttccgttttt tcttaggatt cattgctttc
    16021 ttaagagcac gttctctttc gcggattctc cgtgcttctt cttcacgctc ttttcgaatt
    16081 ttgaaagggt tgttgatcag cagcgtttgt acaacttgga aggcattgga aactacccag
    16141 tataatgaaa gaccgctggc taaattgaca cccatcacta aaatcattac aggcatcacg
    16201 aaattcatga tcttcattga tgcattcgat tcaatttgac tcatgctaga taaatacgta
    16261 cttgcaaaag taaagattgc tgctaaaatc ggcaaaataa atgttggatc cgcgttccct
    16321 aagttcaacc ataagaaatg cccttgtttc aactctggta cacgtgaaat agattgccat
    16381 aacgccatca agattggcat ttgtactaat aaaggaagac aaccagcata tggattgacg
    16441 ccattttctg catataaacg ctgctgctct tctcttaact tactttgtgt ttccggatct
    16501 cttgaactat attgttgctg cagtgctttt aatttcggtt gtaattcttg cgttttacgc
    16561 atgctctttg tttggaaatg catcaacggc aataggatca cgcggatgat cagtgtaaat
    16621 aaaatgatcc ctatccctgc attaccaaat gacaacgcct tgatcgcctc agcaaagtaa
    16681 taaacaatat aacgatccca aattcctgta ctctgtgcgc tgacttcccc agttccgcaa
    16741 ccggataaga cgatgaccaa actaacgata ccggccatca aaagtaaacg tttgtatttc
    16801 ttcacttact cttttcctct ctgtcgatta tttttgcaag ttttaagacg tggactaaat
    16861 tggagcgaac ctcatcataa gtcaacccct tcacacttgg tctagcaatc acaataaaat
    16921 ccaactccgg atcaatttct tcttttatag aataaactgc tgctcggatt tttcgtttga
    16981 cttcattgcg gtttaccgcg ttgccgacct tttttcctac agataaacca actcgaaaat
    17041 gaggctgtcc cggtttttcc aaacggtaaa cgacgaattt gcggttagca aaagaatctc
    17101 ccgtatggaa cacggcttga aactctcgtt ctttttttac tcgatacgct tttctcatta
    17161 gttttctttc cttttctatc tctcacttac gctcataatc ataccataat tacgattgtc
    17221 ctttcatcat ttccctaaaa aagagtataa aaaaaaccac tgaaacccca gtggcctaag
    17281 ctgaaagaac ttttcttcct ttgcgacgac ggctagctaa cacacgacgt ccatttttag
    17341 tactcatacg tttacggaat ccgtgaactt tttgacgttt acgtttattt ggttggtatg
    17401 ttcttttcat atattccacc tccaaaatgt tcttatctat tttataaaca cagacatact
    17461 ttgatagtat aacgacaaag tagtgatttt gtcaatataa aatagaagat cgattgttaa
    17521 aacttatcca caagattatt tttttctatg ggaatcctat gtggaaaaag ttatgcacag
    17581 ggattatcca cagataataa aaggctggtt ttacacagaa aacacacgtg taaaaaaagt
    17641 aatccacaat caggcgattt cctgtgtatt ccgtctccta actattggta tatctgtatt
    17701 ttttatccac agacgcaaga ggaaatctat tggtttttac gagttttcca cctgtgcatt
    17761 agtggtgtgg aaaacttttt ttgacaactg tgtttttctc ttttttcttt ttgtcgattg
    17821 tgtggataat tgtaattaaa aaattttttt cttcggtttc tgtggaaaac tattgaaaaa
    17881 aatgctaaat tagtactagt tattcacttt ttaatgaagg aggaggcctt atatggtatc
    17941 cctcgatgct ttatggaatg aattaaaagc aacataccaa aaggatttat cgcctgctag
    18001 ctataataca tggatcgaaa cagcgaaccc tcgaaccctt gatcaaaacc agctcgttgt
    18061 tgaggttcct agcaagattc ataaagaata ttgggaaaaa aacctggcga caaaaatcgt
    18121 tgaagtcggt tatatgttat caggaaatga gattatccct cgctttatta ctggcgaaga
    18181 agcagagcaa gaagaagtta tagaagaaaa aaatccaaaa gttgtggcac ctagtccgct
    18241 aaaaaaagcc atgctgaacc ctaaatatac ctttgatacg tttgtcattg gtaaaggaaa
    18301 ccagatggct catgcagcag cgctcgttgt agcagaagat ccaggttcta tttataaccc
    18361 gctcttcttt tatggaggcg tgggacttgg taagactcac ttgatgcatg caattggtca
    18421 tcaaatgctg caaagtcagc ctaatgccaa agtaaaatat gtaagcagtg aaacttttgc
    18481 taatgatttc atcaattcga tccaaaacaa aacagcagaa gagttccgtc aagaatatcg
    18541 aaatgttgat ttactgctag tggatgacat tcaatttttt gcagaaaaag aagctacgca
    18601 agaagagttt ttccatactt tcaatgcctt gtacaatgaa gggaaacaaa tcgtactaac
    18661 cagtgatcgg ttgccaaacg agattccgaa actgcaagaa cgccttgttt ctcgctttgc
    18721 atgggggctg tctgttgata ttacaccgcc ggatcttgaa acaagaacag cgattttacg
    18781 taaaaaagcg gcggctgaac gtctagagat cccagatgac acactaagct acatcgcagg
    18841 acaaattgat tctaacattc gtgaattaga aggtgcgctt gttcgagtgc aagcttttgc
    18901 tgcgatgaat agtgaagata tttcgactag tctagctgca gacgcactga aaacgttaaa
    18961 atcaggaaaa ggacatcctc aattgtcaat cctgcagatc caagaagaag tggcaaagta
    19021 ttatcacatc caattgaaag atctcaaagg aaagaaacgc gtcaaatcta ttgttgttcc
    19081 tagacaaatc gctatgtatt tggcacgtga gctcacagat aattctttac cgaaaatcgg
    19141 agctgaattc ggtggcaagg atcatacaac ggttatccat gctcatgaaa aaatccagca
    19201 gctgatggat tctagtgtca gtatgcaaaa tgaagtatca gaaatcaaaa actttttact
    19261 aaattaattt gtcgattcta tcaactgaaa atagcatgtg gataaaagaa aaaaacgttc
    19321 aaaagttata cacacttttt ccacagctgt tttttcgttt ctctcttacg ttttttgagt
    19381 tttccacaga atcaacatgc cctattactt ttattattct ttttaactaa taataaataa
    19441 acaaacattc aaaggagata catcatgaaa gttactttaa accgagctag ctttatgcag
    19501 gaattgcaaa ctgttcaacg agctatttca agcaaaacca cgatccctat tttgacaggt
    19561 gtaaaaatca cactgacaca agaaggtttg actttgacgg ggagcaacgc tgatatatca
    19621 attgaaactt ttttgtctgt tgaaaacgaa aaagcaaata tgcaaatcga atctactggt
    19681 tccattgttt tacaagcacg tttctttagc gaaatcattc ggagacttcc tgaagaaaca
    19741 tttactttag aagttttaga aaataaacaa gtagcgatca cttctggaaa agcgaatttt
    19801 atcgtaaatg gattagatgc agataactat cctcatcttc ctgttgtcga aagccataac
    19861 cagatgaaat tacctgtaca cgtattgact aaactaatca acgaaacagt ttttgctgtc
    19921 tcacaacatg agagtcgtcc aatcttgaca ggtgtgcatt tcattttatc tgataattct
    19981 ttattagctg tagctactga ttctcaccgt ctaagtcaac gcgtgattcc agtagaacaa
    20041 gcggctgatc attttgatat tgttattcct ggaaaaagtt tgatcgaatt atctcgctca
    20101 ttaacaaatg aagaagaaat cgtcgaaatc agcattatgg aaaaccaagt gttgttcaaa
    20161 acagaaacga tgtatttcta ttcccgtttg ctagaaggaa actatccaga taccaatcgt
    20221 ttgattcctt caagttttaa tacagaggtt gaattttctg ttcctagctt tttagcggcg
    20281 atcgaacggg cttctttact ttctcatgaa ggccgtaaca acatcgttcg tttatctatt
    20341 cgtccagatg cggttgtttt atacggaaat tcgccagaaa tcgggaaagt agaagaaagc
    20401 ttgagttata cagcaagcag tggcgatcca ttagatattt ctttcaatcc ggattatatg
    20461 aaagcagcgt tgcgtgcatt tggagatatg agcatcaaag tgaaatttat ctctgctatt
    20521 cgtccattta cattggaacc aacggaagat ggcgttcaat ttattcagct gattactcct
    20581 gtacgtacaa attaacaatg attttcaatg ttcttgaaaa tttaattgaa aagaaataga
    20641 aaaaataaaa ttttaaacag aaggccctaa aatctctttt aaggctttct gtttattttt
    20701 gtttaaatca ccttttttag attaaatcgt cttatatgga aaaatatatg gataaatttg
    20761 ttttattgcg aaaaaaaagg tataatagag tatactttta ataatgaaaa tgagggatgg
    20821 gcattgaaac aacaagtcat tctaaatacg gaattcatga cgttgggcca aatgttgaaa
    20881 gaagtcacag ttatcggtag tggcggacaa gcaaaatggt atttggcaga aaacactgtg
    20941 ttagtcgatg gcgaaccaga aaatcgtcgt ggacgcaaac tttatcccgg catgatggtt
    21001 gaagttccag aagtaggaac tttttttatg gtaaaaaaag gaaacgacga taatgaggct
    21061 gaataagctg tatttaaaaa attatcgaaa ttacgaagag ctgaacatcg aattttccaa
    21121 gaacctcgtc atctttttag gagaaaatgc gcaaggaaaa acgaatcttt tggaaagtat
    21181 ctacgtatta gctatgacgc gaagtcatcg gacaagtagt gagcaggaat tgattggctg
    21241 gactgacgat caggcgatga ttcaaggaga gatcacaaaa ggttcatcca ctcttccatt
    21301 agaaatctta ttatctaaaa aaggccgaaa aaccaagatc aaccatatcg aacagaaaaa
    21361 gttaagtact tacgtgggac aaatgaatgt cattttattt gcaccagaag atctttcttt
    21421 agtaaaaggc agcccgcaga ccaggcggaa gtttttagat atggaattag gccagatcaa
    21481 tccaatctat ctttatgatc ttgtccaata ccaagcaatt ttgaaacaaa gaaaccagta
    21541 cttgaagcaa ttgaatgaaa aaaaacaaac tgatttgctt tatttggata ttttgtccga
    21601 acaactagca gcgtttggca gcaaagtatt gaaagcaaga gcacagttcg tcaagcgatt
    21661 ggagttttgg gctaattctt tgcatcagca aatcacccat caaaaagagc agctggaaat
    21721 cgagtatctc accgcagtcg attctttaga aacacatacg caagagcaaa tccaagaaca
    21781 atttctcgca cttttgaacc aaaataaaaa gaaagacctt tttcggggaa caacgacagt
    21841 tggtcctcat cgtgacgatc tttccttttt tattaatcag aaaaatgtgc agacttatgg
    21901 atcgcaagga cagcaaagaa caactgcact aagtgtcaaa ttagcagaaa tcgatttgat
    21961 taaagaagag acaggggaat atccaatcct tttgttagat gatgtgatga gcgagctgga
    22021 tgataatcgt caactccatc tgctagaaac aatcgaagga aaagttcaaa cgttcttaac
    22081 aacaacgaca cttgaccatg taaaaaataa aatgactgtt gaacctgaga ttttttatgt
    22141 tcaacaaggg aaactaaaag gagaagaaac tgaatgacag aagaaagaag tttagtagaa
    22201 cgcgctaaag agtatgatgc cagtcagatt caagtacttg aaggacttga agccgttcgt
    22261 aaacgacctg gcatgtatat cggttcgact agttctgagg gtctgcatca ccttgtttgg
    22321 gaaattgtcg ataattcgat cgatgaagta ttagcaggtt ttgcaacgaa aatccatgtg
    22381 attattgaaa aagacaacag tatcaccgtt attgacgacg gtcgggggat acctgtagat
    22441 atccaggcaa aaactggacg tcctgcagtt gaaacggtct ttactgtttt acatgctgga
    22501 ggaaaattcg gcggtggtgg gtacaaagtt tctggtggac ttcacggagt aggatcttct
    22561 gttgttaacg cgctttctac acagcttgat gtcaaagtat acaaagaagg aaatgtgtac
    22621 tatcaagaat atcgtcgtgg agctgtagtg gacgacttaa agattatcga acaaacggat
    22681 cgccatggaa caacggttca ctttacgcca gaccctgaaa tttttacaga gacaactgag
    22741 tttgattttt caaaattggc tacccggatc cgtgaacttg ctttcttgaa ccgcgggatg
    22801 cgtatatcga ttgaagacaa acgagaagaa gaaccagtca tcaatgaata ccattatgac
    22861 ggcgggatta aaagttatgt cgaatacttg aatgcaaaca aaaccgtgat ttttccagaa
    22921 cctgtatatt tggaaggtga acagcaagat atcgcagttg aagtctctat gcaatataca
    22981 gacggctacc attccaatat catgagtttt gccaacaata tccatacgta tgaaggcgga
    23041 acacatgaat caggattcaa gactgcttta actcgtgtga taaatgatta tgcccgaaaa
    23101 caaaagctga tgaaagaaaa tgacgacaac ttgaccggtg aagacgtgcg agaaggattg
    23161 acagctgtta tttctatcaa gcatcctgac cctcaattcg aaggacaaac aaaaacaaaa
    23221 ttgggcaatt ccgaagtacg gacagtcact gatcggttat ttagcgaaca tttcatgaaa
    23281 ttcttgctgg aaaacccaag tgtgggccgt caaattgttg aaaaaggatt actagcttcc
    23341 agagctcgtc tagcagcgaa acgtgcgcgt gaagtaacga gacgtaaagg tgctttagag
    23401 attagtaatc tgccaggaaa attagcggac tgctctagca acgatcctga aaaatgcgaa
    23461 ttgttcatcg tcgaaggaga ttcggccggc ggatcagcta agcaaggtcg taatcgagag
    23521 tttcaagcca tcttgcctat tcgtgggaaa atcttgaatg ttgaaaaagc aagcatggac
    23581 aagatcttgg caaatgaaga gatccggtct ttatttactg ctatgggtac agggtttgga
    23641 gaagattttg atgtatcgaa agctcgctac cacaaattag ttatcatgac tgatgccgat
    23701 gtcgacggcg cgcatatccg tacattgctg ctgactcttt tttatcgtta catgcgtcct
    23761 attgttgaag ctggatacgt ctatattgct cagccacctt tatacggggt aaaacaaggg
    23821 aagaatatta cgtatgtaca accaggaaaa aatgcagaag aagagttgaa acaagtcgtt
    23881 gcttcacttc ctgcctcacc aaaaccaagc gttcagcgtt ataaaggact tggagaaatg
    23941 gatgatcatc aactatggga aacaactatg gacccaagca atcggatgat ggcccgcgtc
    24001 agtgtggacg atgctattgc agcagatcag atatttgaaa tgttgatggg ggatcgagta
    24061 gaaccccgtc gtgcattcat cgaggaaaat gcacactatg tgaagaactt agatatttaa
    24121 tcatgaagga ggaaaaagaa tgagtgaaga aatcagagaa aacatccatg atgtcaatct
    24181 aaccagcgaa atgaaagact ccttcatcga ttatgcgatg agtgttattg tcgcacgtgc
    24241 acttcctgat gtcagagatg gtctgaaacc cgttcatcgc cgtattttat acggcatgaa
    24301 cgaattaggt gtaacaccgg ataaagccca taaaaaatct gccagaatcg tcggagatgt
    24361 catgggtaaa taccatcctc atggagacta tgcgatctat gagtcaatgg tacggatggc
    24421 acagccattc agctaccgtt atatgctagt ggatggtcat ggaaactttg gttctgttga
    24481 cggtgacggt gccgccgcta tgcgttatac cgaagcacgg atgagcaaaa tcgctacaga
    24541 aatgctgcgt gatatcaata agaacactgt tgatttccaa agcaactatg atgatacaga
    24601 aaaagaacca gttgtactac ctgctcgctt cccgaatctt ttagtgaacg gaacaacggg
    24661 gatcgccgta ggtatggcca cgaatatccc acctcataac ttgtctgagg tagtagcggc
    24721 tatcgatttg ctgatggata atcctgatgt gacgaccaat gaattgatgg aagtattacc
    24781 tggaccagat tttccaacag gtggtttggt tatgggaaaa tcaggaatcc gaagagcgta
    24841 tgaaacaggt aagggttcta ttaccgtacg tgcaaaagtt gagattactg agatgccaaa
    24901 tggtaaagaa cggatcatcg tgacagaatt gccttatatg gtcaataaag caaaattgat
    24961 cgaacggatt tctgaactgc acagagacaa gcgtatcgaa gggatcacag atttgcggga
    25021 cgaatcttcc cgtgaaggta tgcggatcgt cattgacatc cgtcgtgacg ccagcgcatc
    25081 tgttatcttg aataacttat ataaattgac atccttgcaa aattcatttg gattcaatat
    25141 gttggcgatc gaaaaaggtg tgccgaaagt tttgagcttg aaacaaattc ttgaaaacta
    25201 tatcgaacat cagcgcgaag tcatcacaag acggacagtc tttgaaaaag aaaaagcaga
    25261 agcaagggca cacattttag aaggtttgcg tattgctttg gatcatatcg atgaaatcat
    25321 tgcgattatc cgcgggtcta aatcagatga cgaagcaaaa gcgacgatga tcgaacggtt
    25381 cgatttatcc gatcgccagt ctcaagctat tttagatatg cgtttacgcc gattgaccgg
    25441 tttggaacgg gaaaaaatcg aaaatgaata ccaagaactc ttaaaactga ttgaagattt
    25501 aactgacatt ctggcaagac cagaacgtgt tacagaaatc atcaagaatg aattagcaga
    25561 cttgaatcaa cgatttggtg ataaacgacg cacagaatta ctagtcggtg aggtcttaag
    25621 tctggaagat gaagatttaa tcgaagaaga agaaatcgtt attacattga caaacaatgg
    25681 ttacatcaaa cgtttggcaa ataatgaatt cagagctcaa cgaaggggtg gacgtggtgt
    25741 ccaaggaatg ggtatccaca atgacgactt cgtcaaaaat ctggtttctt gttctaccca
    25801 tgatacattg ttattcttta cgaataacgg aaaagtgtat cgggcaaaag gatacgaaat
    25861 tccagaatac gggcgcacag ccaaaggaat accaattatc aatttactag gtatcgattc
    25921 gagtgaaagc atccaggcaa tcattgcggt gacgggagaa gcagaagaag gccactatct
    25981 cttctttacg acgcgtcaag gtacagtaaa acgtacttct gtcactgctt ttgctaacat
    26041 ccgaagtaat ggtctgatcg caattggttt gaaagaagac gatgagctcg tcaatgtgct
    26101 actgacagat ggtcaatcta atatcattat tggaacacat aacggctact ctgtcacttt
    26161 caaagaagaa gcagtccgcg atatgggacg tacagcttcc ggggttagag gaatacgcct
    26221 gcgtgaggaa gattatgtcg ttggggcagc cttaatgaag gaagatcaag aagtattagt
    26281 gatcacagaa aaaggttacg gaaaacggac aaaagtatcg gaatatccag tgaaaggccg
    26341 cggaggtaaa gggatcaaaa cggcgaacat cactgaaaaa aatggtccac tagctggatt
    26401 gaccactgtt tctggagatg aagacatcat gctgattaca gataaaggtg tcattatccg
    26461 tttcaacgta tcgactgttt ctcaaactgg acgttcaaca ttaggcgtac gtttgatgaa
    26521 gatggaagct gatacgaaag ttgtcacgat ggcagcagtc gaaccagaag ctgcagaaca
    26581 aacagttgaa gaacaaggat cagaagaata gccatcaaga ctaattgtgt aagctagcaa
    26641 gaatgaccga ttaaaaaatc tggttattcc tgctggcttt tttgattagt tgaatttctc
    26701 ttaaaatatt cgaaactgtt cattctgtat tgcttttgac caaaatagag tgtataatca
    26761 gagcttgtga gtagtctaat taattagata actctccttg ctcttaggaa cctaagagcc
    26821 gaaagtccac agggaggtga atatcaatgg aaaacacgaa atatgaaatc atgtacatta
    26881 ttcgtccaaa cattgatgaa gaagcaaaaa ctgctttaat cgaacgtttc gatgcaatct
    26941 tgaaagataa cggagcagaa gttatcgaat caaaagattg ggaaaaacgc cgtttcgctt
    27001 atgaaatgaa cggttaccgt gaaggtatct atcacatcgt taaagtatct tctccatcat
    27061 cagcaaatgc tgtcaatgaa tttgaccgtc ttgctaaaat caacgacgat atcattcgtc
    27121 acatgattgt taaagaagaa gcttaattgt tgtttcatgt gaaacaatag aaaacgatga
    27181 gaggagatga ctattttgat taataatgtt gtattagttg gacgtctgac gaaagatcca
    27241 gatttgcgtt acacagcaag tggtacggca gtcgcaacat ttactttggc tgtgaatcgt
    27301 aattttacaa accaaagcgg caatcgcgag gctgatttta tcaactgtgt gatttggcgc
    27361 aaatcagcag aaactttagc aaactatgct cgtaaaggaa cacttttagg tgttactgga
    27421 cgtatccaaa ctcgttctta tgataatcag caaggacaac gtgtatacgt gacagaagta
    27481 gtagctgaca acttccaatt gctggaaagt cgttctgcat ctgaaaatcg ccaacaaagc
    27541 ggcggattcc aaagttctgg tcaatcagct ggcggatttg gcggaaacaa taactctaat
    27601 caaacatctc aatcatccaa cggtatgcct gatttcgacc gtgatacttc tgacccattc
    27661 ggctcaagtt caacgatcga catttcagac gatgatttac cattctaaac gaatttgata
    27721 ggagggaaat agaatggcac aacaaagaag aggcggacgt aaacgtcgta aagtagacta
    27781 cattgctgct aaccatattg aatatatcga ttataaagat atcgaattac taaaaagatt
    27841 tatttcagaa cgcggtaaaa tcttgccacg tcgtgtaact ggtacaggcg ctaaaaacca
    27901 acgtaaaatt actgttgcaa tcaaacgcgc tcgtatcatg ggcttgctac ctttcgttag
    27961 cgaagactaa taaatcctag gaattgaatg actgatcctt ttgatcagct attcaattcc
    28021 tttttttctg taaaaataac ctctattcgt ttagtcgctc gaatgacgaa agttatggta
    28081 aaatcaaatt agtcatatat gggaggaaaa ttatggaaaa taaaaacaat catttatccc
    28141 cgaaacctct cttccttatc ctgtttatat taatcgaagt attggtagtc ttaattttac
    28201 catttcgttt tgttagcgct tcggtcattc tattgatgaa tttatggggt gttcgctatt
    28261 ggttgaaaat gaaacgttgg cttattttaa ataaacgtga aaaaatccag caggcttcga
    28321 ctgtagctga aaccaatcta gcttatgtct cagaagtcat gcctgtagga gtgattgctt
    28381 atcagccatc aagccaaaaa atcgaatggc tcaatccatt agcattgaaa atcaaagatc
    28441 aaagtggatt aacagaggaa gaattgctag atactttttt tactgcaaaa gaaaaaaaga
    28501 aaaaccaagt ctatctagca gataaaacat ttcagtttga tatggataca gtaaagggtg
    28561 ttgtttattt taatgatatt acccaaaacc agttgttaaa actccatcag acgaacagtc
    28621 agccggtgat tggtatttta tctattgata actatgcaga tgccattgat aaattggatg
    28681 acaaagagat ttcttatttg aactctttcg tcactacact agtttctgac tggatgaatg
    28741 aataccatgt ctttttcaaa agaatcaacg cagaacggtt tttcttcgta gcacagatga
    28801 tcgatctgaa aaagatgatg gataaaaaat ttgatttgct ggatcgcttt cgagcagaag
    28861 ctgaaaaaca gagctcgcct atcaccctta gtatggggat tgcttatggc tcaagaaccc
    28921 tcgatgaaat cggtggagaa gctcagaata atttagatgt tgctttagtc cgtggaggcg
    28981 accaagttgt cgtgaaagag gtaaaagaag gagcaaaacc tgtttattat ggggggaaat
    29041 ctgctaagaa tgtcaaacgc acgcgtgttc gttctcgagc gatgagtacc gctttgcgtc
    29101 ggatttttga tgaaacaggc gatgtgttta tcatggggca caagtttccg gatatggatg
    29161 ctttaggctc tgcttttggt gtcagttgtc tggcacgctt caaccagaaa aaagcttaca
    29221 tcgttatcaa cgagaacgag atcattccag atgtagaacg gtgtcttgaa gaaatccata
    29281 agcatcctga attagaaatg caactaatct ctccagaacg tgccatagag ctgaaaaaag
    29341 aagaggacct cctcgtgatg gtggattacc ataaaccttc tctatcgatc tctcagggcc
    29401 tatatgagca atttgataag attgtgatca ttgatcacca tcgtcgtggg gaagagtttc
    29461 caagtaaacc tctgctgact tatatcgaat cttcagcttc ttcagcttca gagctagttt
    29521 ctgagctgat ccaataccaa agcagcaaaa caaatcgctt agatcgtttt gaggccacat
    29581 tattgcttgc agggatggtt gtagatacaa atagtttcaa tgtccgtaca actgcacgaa
    29641 cttttgacgt tgccagctat ttaaggtctt gtggagcaga cgcatcctta gtacaatatt
    29701 tattgagctc ggatttagcg acatacttgg agatcagcaa tttgattgct ggaagcgact
    29761 atgtgacttc tgatattgtt gtggcggcag ggacagacga aaaagagtat aatagtgtta
    29821 tagcagcaaa aacagcagat acattgcttt cgatgatcaa tatcaatgca gctttcgtca
    29881 ttacaaagcg gacagacggc ttgattggga tcagtgccag aagtaccggc acgatcaacg
    29941 tccaaatcat catggaatcc ttaggtggcg gaggacactt cacaaacgca gctactcaac
    30001 tggaaaatac gacagttgag gaaacaaaac agaagctatt tgctgcaatc aaagaaaata
    30061 tgaatcaaat atatgataag gagtaatcca aatgaaagta atttttttac aagatgtaaa
    30121 aggaaaaggt aaaaaagggg acatcaaaga agttccagca ggttatgcac aaaattatct
    30181 aatcaaaaat aacttggcaa aagaagcaac gaaaagcagt atcagtcagt tagcaggaca
    30241 aaagaaagca caagaaaaac acgaagctga aatcttggaa gaagctaaaa agttaaaaga
    30301 attcttggaa aaagaagata ctgtagtcga attgaaggcg aaagcagggg aagacagccg
    30361 tttgtttggt tcgatccctt caaaacaaat tgctgaaggg ttaaacaaac aatacaaaat
    30421 caaattagat aaacgaaaaa tcgaattaga aaatccgatc cgttcactag gctacacaaa
    30481 cgtacctgtt aagcttcatc atgaggtgac ggctacgatc aaagttcatg tcgtacaaga
    30541 ataacaaatc ttgatagcga tgttcagctg gtaagtataa ccagaaggaa aaaagacaaa
    30601 ccgaaattta tctgagaaaa cagctgcagc aatgaaagca aaagctgcaa atcgatttca
    30661 gattgatttc ggtttctttt ttgggaacag caaaatagca taaagaaaac gagtataata
    30721 aaagagaact atttttttat tacactttcg gtacgaatga tgacttttct ctcattttct
    30781 tgtaaaatga agcaattgaa gacaaggagc gatacgtatg aatgaagtgt ggcaggatcg
    30841 aatcccaccg caaaatattg aagctgaaca agcggtttta ggctctgttt ttcttgacgc
    30901 agaaacgatc attgatgcca tggagtacat agagccaaaa gacttttatc gtcgtggcca
    30961 tcaaattatt tttgagacaa tgatcgagtt aaatgatcgt aatgaagcga ttgacgtggt
    31021 tactgtcaaa gaccggctgg aacaagccaa tttgttagaa gatgccggtg gtttaagtta
    31081 tctctcagac ttggcattag cagttccgac agcagcaaat atcgtctact atgcgaaaat
    31141 cgttgaagaa aaatcattgc tgcgtacatt gatccagaca gcaacaggaa tcgttacgaa
    31201 aggattcgag caaggagaag aagttcaaac aattttagat gatgccgaac gcagtatctt
    31261 ggaggtttcg gaaaaaagaa atcgaagcgg ctttttatct attgctgaag tactgaactc
    31321 cacgattgaa aatatcgatc gactagctca aaacaatgaa gaaatcacag gtctaccaac
    31381 tggctatcaa ggtctggata aaatgacagc aggtttccag cccgaagaac taatcattct
    31441 tgctgcacgt ccagcggtag gtaaaacagc gtttgcattg aatattgctc aaaatgtagg
    31501 aacaaaaaca gatcgttctg ttgcgatatt tagtttggaa atgggggcag aatctcttgt
    31561 aaatcggatg ctttgtgcag aaggttcgat tgaggccagc catttacgta caggtcagct
    31621 ttcggaagaa gaatggtcga atctgatcgt tgcgatgggg agtctttctc gagcaaatat
    31681 ttttatcgat gatacaccag ggatcaaaat ctctgaaatc cgtgcgaaat gtcggaaact
    31741 agcgcaagaa aaaggcaatc taggcttgat attgatcgat tatttgcagt tgattgaagg
    31801 taacggtaaa gagaaccgtc aacaagaagt atcagatatc tctcgccaac tgaaaaaact
    31861 ggcgaaagag ctgaaagtac ctgtcattgc tctttcacag ttatctcgtg gagtagaaca
    31921 gcgacaagac aaacgaccag tgctaagtga tattcgtgaa tccggatcaa ttgaacaaga
    31981 tgcggacatc gtagccttct tgtatcgaga tgattattat gaaagagaag gcggagatga
    32041 cgatgatgga aacgagccaa aaaatgacaa cgtcatcgaa gtcatcatcg agaagaaccg
    32101 aagcggtgca cgaggaacag ttgaactact gtttatcaaa gaatacaata agttttcgtc
    32161 gctttcgcca agagaagaat tttaaagaag aggttgtgag ccttgagcaa tcccgagagc
    32221 tctcgtaaga agatgcaagg agtaaccgca ggaacgacta gagtacttaa tttaaacaga
    32281 tctccaaagg gattgtgaca aaagtcttgt cacagtccct ttttccgaat aaacggtgtt
    32341 caatcagctg acccttggta ttagctcagc aaacgtcaaa atatgaggaa ctattttgac
    32401 gtttgtttct ctaatactca ggtcaaaacg ctgatcttac gacctctttt ccttaaacgg
    32461 tgttctcctg ccaactcctc ggtcacaagt cacaatatca tcaaacatga gaagcagttt
    32521 tttgaaattg ctccttgtga ctcagagtta aacggcaggc tcacaacctc tttcttaaac
    32581 ggtgttcaaa agcttgcatc tgcggtaata cgcccaatca aacgaaaaat atgagaagct
    32641 atttttgttt ggctgttctt attacttgat gcaggacagc tttttcacaa cctctgattc
    32701 acggtgttcc aaaagtagct tcttcgaaaa ataagtcgaa atttcacaaa aatttgagaa
    32761 gcaattttcg tacattcctt cttatttctt gaagctgacc acttctgtta caacctcttt
    32821 tttaataacc attctaaaaa gataaagttc gttttttaag cgtttttata aaataaaaat
    32881 aaaaatcatt cgattttatt tgaaatatgt atctattatt gatacaatgg ttcaggatta
    32941 aataatatag aacgaggtgt tcacatgtca tctgtagtag tagtaggtac gcaatggggc
    33001 gatgaaggga aaggaaaaat cacagacttt ctcagtgaaa atgctgaagt gattgcacgg
    33061 taccaaggtg gcgacaatgc agggcacaca attaagttta acggtgtgac ttataaactg
    33121 catttgattc cttctgggat tttttataaa gacaagatca gtgtgatcgg aaacggcgtt
    33181 gtagtcaatc ctaaatcatt ggttaaagaa ttagcttatt tacatgaaaa aggtgtagaa
    33241 acaagtaatt tgcgtatttc tgaccgcgcg cacgtaatct tgccttatca tatcaaattg
    33301 gaccaattac aagaagatgc taagggcgaa aataagattg gtacaacgat taaaggaatc
    33361 ggacctgcct atatggataa agcagctcgt gtaggtatcc gtattgcaga cttattagat
    33421 aaagaaattt ttgaagaacg tcttcgtttg aatctagatg acaaaaaccg tcaatttgta
    33481 aaaatgtttg attcagaacc acttgatttt gacgatattt ttgaagaata ttatgaatac
    33541 ggacaacaaa tcaaacaata cgtcacagat acttccgtta tcttgaatga tgctttggat
    33601 gcaggcaaac gcgtgttgtt tgaaggcgca caaggtgtaa tgctggatat cgaccaggga
    33661 acttatcctt ttgttacttc ttctaaccca gtagccggtg gggtaacaat cggaagcggt
    33721 gtagggcctt caaaaatcaa taaagttgtc ggcgtctgca aagcctatac gtcacgtgtc
    33781 ggtgatggac catttccaac tgaattattt gatgaaacag gagaacaaat ccgcgaagta
    33841 ggacgagaat acggtacgac aactggtcgt ccgcgtcgtg taggctggtt tgattctgta
    33901 gttatgcgcc attctaaacg agtttcaggt attaccaacc tatctttaaa ctcgatcgat
    33961 gtattaagtg gattggaaac agtaaaaatt tgtacggctt atgaattaga tggcgaacta
    34021 atctaccact atccagcaag cttgaaagag ttgaaccgct gcaaaccaat ctatgaagaa
    34081 ttgccaggct ggtcagaaga cattacagga tgcaaaacac ttgcagaact gccagaaaac
    34141 gcacgtaact atgtacgtcg tatctcagag cttgttggtg tacgtatctc aacattttct
    34201 gtcggacctg atagaacaca aacaaacatc ttagaaagcg tctgggcgca aatctaagga
    34261 taaaaacgac gactgaatca ggacgttctt accagagcga gtcgaagtgt ttatctatac
    34321 gataataata acttgaacac tgtttattca gaataaggga ctgtgacaaa aaccgtgtca
    34381 cagtcccttt ttccgaacaa acggtgttca aaagcttgca tctacggcac taagcccaat
    34441 cagatgaaaa atatggagtg ctatttttat ctgattgttc ttactgcttg atgcagagca
    34501 gctttttcac aacctctcca ctaaacggtg ttctcctgcc aactcctcgg tcacaagtca
    34561 caatattcaa caaacatgag aagctgtttt ttgaaattgt tccttgtgac tcggagctaa
    34621 acggcaggct cacaacctct tggtaaacgg tgttcaatca gctgaccctc ggtattagct
    34681 caaaaaacgg caaaatatga ggaactattt tttccgtttt tttctctaat actcaggtca
    34741 aaacgctgat ttcacaacct ctgattcacg gtgttccaga agtagcttct acggaaataa
    34801 gccgaaattt cacaaaaatt tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag
    34861 ctgaccactt ctgtcacaac ctcttatttt gattagaact tgcgaaaata aaccggttaa
    34921 agtgtgtcta gcgcaagaga tttgctataa tagacgataa gggtaaaatg taacgagaag
    34981 gggttgaaaa atgtgtatca aattgtaaca gattcttgtt gtgatctgcc ataccatgta
    35041 ttagcaaaag aaaaagttga ttttttatca atgaatctcc aattgaatga tcaagagtta
    35101 gtagatgacc tcggaaagac attcaattat gaccgctaca tgaatcagct gaaaaatggt
    35161 gcgatgccta cgacatcaca aatcaatgtt ggccgatatt tagaattttt ccgttcttat
    35221 gcggaaaaac agattcctgt tttatatgtg gctttttcca gtggattaag cggctcttac
    35281 agtagtgcgc ttcaagcggt tgaattgctg aaggaagaat atgaagaccc tgagatctat
    35341 gtttttgata caaaagctgc aagtattggg gaagggcttt tagtattgga agctgtaaga
    35401 ttgaaaaaag aaggtaaaag catcgaagaa accctagagt ggctggaaag taattatttg
    35461 aaagtccatt catgggtaac agtagacgat ctgaaatatc tagaacgagg cggtaggatt
    35521 tccaaagcaa gtgctactct tggcagtcta ttgagtgtaa agcctattat tacggtggat
    35581 aaagaaggaa ggctgacgaa tgttgacaaa gttcgaggaa gaaacaagtc gatccagaca
    35641 atcgtcaatg agacggtaaa aacaatcgtt gcaccacttg atcaaatcgt ttatgtggct
    35701 tacgctgggg atctagagag cgcggagaag gcaaaacggc ttttggaaga gcagataaag
    35761 atgaaagatg tgaagcttta tcccttagga ccaacgatcg ccagtcacac aggctatggc
    35821 tgtatcgcga ttttttcgat gggaatcagt cgataaaagc agtaactcat tctgtaaaaa
    35881 agcccagaaa ttgattgtaa caaaaacagc gactcttaaa agatagatga gcatcctatc
    35941 tcttagaggt cgctgttttt ttatttttta agctaaatag gccattatgc ccataactcg
    36001 ttcaattgtt tttgaatatc tgcattttcc aaaaattcat catatgtcgt atcagctcga
    36061 tcgatcacac ctttatccga aacggcaatg atgcggtttg ccaatgtttg gataaattga
    36121 tggtcatgtg acgcaaataa gattgagcca gtaaatgcca tcaagccgtc attcaatgct
    36181 gtgattgatt ctaagtctaa atggttcgtt ggatcatcta atacaagtac gttagctttc
    36241 gaaagcatca tttttgaaag catgcaacgg actttctctc caccagataa aacattcact
    36301 ggtttcaata cttcttcacc agaaaacaac attcttccta agaagcttct taagaaggtg
    36361 ttatcatctt cttctttact tgcatattga cgcaaccagt ctaaaatcgt tagatcagta
    36421 tcgaattctt tcgttgtatc ctttggtaaa taagaattac ttgttgtcac accccaacgt
    36481 actgttccag tatctggcgt aatttcaccc atgataactt tgaatagcgt tgttgttgtt
    36541 atatcatttt ctgcgacgaa agcgaccttg tcttctttgc tcaaattaaa agatatatca
    36601 tctaaaattt tctttccatc aatcgttaca cttacatttt ctacctgcaa taagtcgttt
    36661 ccaatctcac gttcaggttt gaatccaacg aatggataac gtctagaaga aggttggata
    36721 tcgtctaaag taattttttc aagcattttt ttacgtgaag ttgcttgttt tgattttgat
    36781 gcattcgcac taaagcgggc aataaattct tggagttctt tgatttgttc ttcttttttg
    36841 gcatttgcgt ttgcttgaag tttagccgct agttgactag attccaacca aaaatcataa
    36901 tttcctacat aaagtttgat tttaccaaaa tctagatccg ccatatgtgt acatactttg
    36961 ttcaaaaagt gacggtcatg ggatacaacg atcacagtat tttcaaaatt gatcaaaaat
    37021 tcttccagcc aattgatcga ttggatatcc agaccgtttg ttggttcgtc tagcaaaaga
    37081 acatcaggtt taccaaatag tgtttgtgct aataacactt ttaccttttg tccaccagtt
    37141 aattcactca tttgctgatg gtgcaattct tcagggatgt tcagaccttg cagtaaaaca
    37201 gctgcttctg gttcagcttc ccatccatta agctcagcaa attctccttc taattcagct
    37261 gctcgaatac catcttcgtc agtgaaatcc tctttcatgt aaatcgcatc tttttctttc
    37321 agcacttcat acagacgctt gtgtcccatg atgactgttt caagtacagt atagtcttca
    37381 tagtcgtaat ggttctgttt caatacggcc atccgttcat ctggtcccat agtaacggaa
    37441 cctgtggaag gctgcagatc ccctgataac actttaagga acgttgattt acctgcacca
    37501 tttgcaccaa tcaagccata gcagtttccg ggggtaaatt taatattcac atcatcaaat
    37561 agtttgcggt ctgaaaagtg caaactcaca tcatttacag taatcaattt ttttcctcac
    37621 ttttatcatt attagttttg acaagtctta tagaattata taggggaaag gtaaaagatt
    37681 caaggcaatc gaacattctt tgtgtttcac gtgaaacaga atgaaaaaaa taaaaataaa
    37741 agcggagcga aaatagctac tataggattt attagtttgc aacagcataa tttttgacgt
    37801 tatttataag agggagtact ataaaactgt aaaagaaatg aaagaaggat tgaaaatgga
    37861 tgaaaaaaga accatcgact ggggctcatt gattttggga attttatttg tacttgtctc
    37921 attgttatca tttcaagacc ctgtcggaaa tttagttgca attgtagtag tctttgcgat
    37981 ttttgccttt attaaaggga tatttgaact gtttgtacgg aacagattaa aagagctaac
    38041 aggatataaa ggaaagatgc ccttaataat cgggatcatc gatattctag ttggcgtctt
    38101 tttcttattc aatattggtg caggagtcgc agcattgcct tttgtttttg cagtatggtt
    38161 tattgctgat tcagttttag cgttatttac tgctgacttg gcaagaggag taagtgaagg
    38221 atattattgg tttacgatca tcgtcaatat tttaggaatt ttattaggaa ttttcttatt
    38281 gtttaatcca atttcttctg cgttgacatt aagcttttta gttggattct attttatgtt
    38341 atttggtatc acacatatcg tctatgcatt tagataagta aaatcaaaca aataaaaaag
    38401 ccggcttccg attacagttt tactgttgta attggaagcc ggctttttta tcatggacaa
    38461 atatgcacga ggtgattttt aggtgtcgag acaaatttat gcaaaaatgt gagaagctat
    38521 atacacaaat tttatcttaa tactcgaagc atagcgcagt tgtcacaacc tcttttcata
    38581 taattcattc aatactggca aatcatggac ttcatatttt tctttgaatg cttggatttc
    38641 ttcttcagaa tattttcttg gatctaaatg cagatcttct actggcaatg ggcgcttgtt
    38701 attgatcttc acatcgatta ctacaggacg atctgatttt gcagctgcat caaaggcaaa
    38761 tcgaagttgc gagtattctg tgactgtaaa gctatttgcc ccgagcgctt ctccaacttt
    38821 accgaaatct gcatcttcta aaaatacacc aaatttcttt tgttccgtat cttcttgttc
    38881 tgcttcgatg aaaccaaaag aatcattcga aaagacaaca ttaataattg gaagctgata
    38941 tttgacttgt gtaatgatat cttgcatgac catagcaaac ccgccatcac cacttaaggt
    39001 aaatacttgt ttttctgggt agcttagttg tgcggcaatt cctcctggca caccattacc
    39061 catagttgcg aaccatccag atgtcgtatg tttttgttta ccgttcatat tcaataaacg
    39121 aatagaatgg atagtcgtgt taccgacatc tgtgacgaaa atcgcatcgt cttcagcaat
    39181 acgattgatt tctttataga cagcctctgg acgaatcggt tcttcctctc gatcttcaaa
    39241 agatttcaac caatttaccc atttttcttt attttcttga tttgctaggt accagctatc
    39301 agcagggcga gcatccccta actcgacaag tctttgcaaa gctgtgtttg catcaccgag
    39361 gatcgacaaa gatgtttcat ggcgtcgtcc aaattttgac gcatcgatat cgatttggat
    39421 aaattcagca gttggattaa aaaatgcacg tccaaatggg aagtcgctac cgacaaataa
    39481 gatcagatcg gcttctgcca atgcttcatt tccgggttta gtagcgacac gtccagcaaa
    39541 accaagaaag ttttcataat catcaggaat aattcctttt gctagaacgg aagcgacaac
    39601 aggaactgaa aaatgttctg agaattcttt gatttgcgga aatccgtttc gcgttccttg
    39661 accaacataa agaactggtt tttttgcttt ttcaagataa ggcaaagcag ctagcaaatc
    39721 tttttcttct ggtaatatca cacttgtttt gtgagtgtga gcggtggaga aaggttgttc
    39781 gtcaatttct tcaaaaccaa gatcaacagg gatagtcacg atagccacgc ctttatgctc
    39841 ataggcggct ttaatggctt catctactac atgcggaaga ctttgtggtg tcatgactgt
    39901 acgattgtat acgctaacat ctgcgaaaat aggattttca tttagttcct ggaaagagtt
    39961 atagttcatg gatgtagaag caacttgtcc taagaacgct actagaggca catggtccat
    40021 ctgtgcatca tacaaaccat tgatcaaatg tgtcgcacca ggtcctgcag agccgaagac
    40081 agcgccgact ttccccgtta attttgcatc tgcagcggct gcgagtgcgc cgacttcttc
    40141 atgacgaact tgaatgtagt tgatttcggt tttttcttga tatagcgcat ccataattga
    40201 attgaaagat cctccgggaa tgccgtaaat atggtcgata ccccagcttt caagaacttt
    40261 taccattgcg attcctgcat tgatttttga catggtgttt cactccttta gcaatgatga
    40321 tacataaatt ttttgtatct agagtataga actttttatc gaaaatccca actaattcgt
    40381 cttttcacaa aaatgtagtc atgtttttgg gaatatgcta gagtagtaca tagatagatt
    40441 caagagaggg gaatggcatg gttgaatggc tattgagact tgaaccttgg cagcaagcac
    40501 ttgctgggac agcttttact tattttatga cagctcttgg tgccgggttg gtttttttct
    40561 ttaaagaaat caaaaaagaa gtgctaaact tgatgttagg atttgcttct ggtgtcatga
    40621 ttgctgcaag tttttggtct ttgttagatc cggctattac aaaagcagaa gaaaatggag
    40681 atattgcttg gctagttgta agtattgggt ttggtttagg cggtgtgttt ttatatatgg
    40741 cagataaaac actgccccat atgcattttg gaccacaaca tgaagcagaa ggattgccta
    40801 cccatttaaa acggacgatc ttgcttgttt tttctattac attgcataac attcctgaag
    40861 gtttagccgt gggggtagca ttcggtgcag cagcaactgc ggataatccg acagccgcta
    40921 tattagccgc tgtttcggtg gcgctaggta ttggtatcca aaacttccca gaaggagcag
    40981 ctgtatcaat cccgttgcga caagaaggtc tgagtcgtaa aaaggccttt gtttacggac
    41041 aagcttctgg aatcgttgaa ccaattgctg gagtgattgg agcgctacta gtaacgaaag
    41101 tggagctgct gcttccttat gcacttgctt ttgccgcagg agcaatgatt tatgtcgtgg
    41161 tggaagaatt gatccctgaa gcacagcaga cattgtccag caaacgtcat tttgcagttt
    41221 ttggcgtcat gagtggattt atcattatga tgattttgga tgtggcatta ggataaataa
    41281 aaaaaatata tatgatatat caaatagggc cgcgaactta tatcgcgacc ctattttttt
    41341 agtaagttat atcataatga agtgaatggt atcatacatt aataatagtt ttttctatgt
    41401 gtatttcctt tgatccagcg aacaagccag atgataagtg cgattgggat tagaactttg
    41461 accgcaaacc ataaaagccc gcttaggaca ctgacaaaaa gactgatgac gaagctagct
    41521 gcaattagca ctaaaagaac catgaagata tttaagaaca tatttttttg acgcatacaa
    41581 aaccctcctc ttgttcattc tttactatag aaaaagtata acagggattg tttaaaaaca
    41641 cctccaactg aagactgatt tttacttcat ctacttaaat gatcaaacaa ttgctttttc
    41701 tctggtttat catctaaaat agagcggaaa aggaggagaa tatcatgcct aaaaatcgtc
    41761 ttgaagcatt tacagatgct gtaatcgcga ttatcatgac tattttagtt ttagaacttc
    41821 atgaacctaa cggagacacg tgggaggcgc tcgctgcatt aggttaccga ttttttatct
    41881 atattgtcag ttttatcatt ttagcgattt attggaacaa tcatcatcat ttatttcaag
    41941 ttgtacataa gataaatgga cgggtcttat gggcgaacag tttctttgtt tttgcgcttt
    42001 cgctttttcc gtttgcaact tcatggatca gtgagtacat caatagcctg gctccagaaa
    42061 tgacttatgg ttttgttacc ttgaccgcta atattgcgta ttatatcttg gcaaaagaac
    42121 ttgtcaaagc aaataaaggc cacgagaaag cattgaaggc gatgttgaat aattacaaga
    42181 aatcgtatct atcgattggt ttgaatgtgt taggaattgt cttagggtat ttagtagcgc
    42241 cagtagccgt gctgatcgca aacatcgtga ttctagctgc ttggatcatc ccaagtcgta
    42301 ccatcgaatc acaatatcgg taaaatgatc cgtgtttaaa atttaagaga aaaatataga
    42361 aaaaataaat aaacgatcaa atatccgagt gatactagta ttcaaagagg gatgcagatg
    42421 gatcaaaaaa gaattcatgt aggactgatt actagttttg tcacgatgct tatttatttg
    42481 gatcaaggtc atttgacttg gacagtagtt ggtgtcgtag gatttttgac attattcaca
    42541 gcaataaaaa aataaacatc tttatgtaat ctgatgttct atctatttaa gaaaagcatg
    42601 tttacagcag tatgattctg ttgtaaacgt gtttttattt gtggaaaatt taatttttag
    42661 aaaagtgtat cgaaaaatag atagttagtt tttccacagt ggataacttc gtaagagata
    42721 aaaataaaaa attagtcaaa gaagggcgta tagatttctt ttgataggag atatacaaca
    42781 gaaatgaata aatattaacg tgttttcaaa cagtataaaa cggtgtggtt tttggaataa
    42841 aaaaataaca tatctcattt tacgcttttg ttattttata cttaaaaaat aacgacacag
    42901 aaaataccgt gtctcagatt tctctactac ttctaaaaac tactgttttt ttcctttgaa
    42961 atgccttcaa aaagtaggat caggcagaat atactggcag aatcaaggag aagggagcct
    43021 aaataaggag aaaaaccata gaaaatataa agtaattact tataaaacaa gctttttata
    43081 gaaaaataat atacctgagt agggtataaa ttaagacgga attcctttct agattgagat
    43141 attgactagg aagaatgtta agattttaag cctttaagct aaaaaaaaac cctttttgtt
    43201 aaataagggg aatatagcct gtcagtttca aactgcaagt cgtcctgctg caataatata
    43261 gtagattaga gatgaaaata gattttttta aaccaatgac tgaataaaaa gaccgtcata
    43321 gatacacatt ggaatgtgtc tattacggtc tttttttacg aacgatttta ttgaagacgg
    43381 acagttcggg tcaaaaataa aaaagctacg atcagaaata agaataaaat gtatcccaaa
    43441 ataatggcta gacggtctaa cttatttgtc gatagatgtt tgtttagaag ttgataggcc
    43501 cataaaccta tcagtcctcc tgttgtatta gttatcaaat cagtgatgtc cgctacgcca
    43561 ataccgaata ggaattgaat caattctgcc aagaagctta caaggaaaat aatccctaat
    43621 tttttagaaa aagaaagtct cttgaaattg acattcaaaa gcaccccaaa aggaaaaaag
    43681 acaatcaagt tataagtggt ctcacgtaat accgtcgtat tttcaaaaga aaaagtagaa
    43741 aaagggacga gattgacatt gctgtaagaa taagtgagaa attgtggaag attaaatgat
    43801 agcttgaata aaatcaacca taatagaaag aataaataaa tccctaataa aaattttgat
    43861 acataccgca tagacatctc ctccatttaa aaagtatacc atcgaaaacc gctgaaaaat
    43921 cataaaaaag tatgaagttt aaggaccaac gtagttatcg tacgaaaatt agaagctttt
    43981 ttttgttggg aatccggttt ctttaacaaa gctaagatag cgagttgctt ggaaaagttg
    44041 ctatcttttt tctgtcaaaa cgactcggaa tgttcgtttt ttgttctaat ttctccaagt
    44101 tgtttacttt ttgatactaa gtttatgaaa aatcaagaaa tagttgttat actaggtaat
    44161 gctgacaaac gggattggca tttcatcttg gttcagcttt ttttccaatt actaggaagg
    44221 agggatagat tgttcaagac ttattttcgt ttcaataaaa tacaagataa tccttttcgt
    44281 atcatgaatc tgatgctact tatctttatt gtattatggt taggttacat aaatcatgat
    44341 tttttgattt caagtttttc atcattaggg atctttactt ttttctatta tcaaaacata
    44401 ccgatgaaat atttgctgaa acgtatgttt ctgatcggtt gcggactgtt ggttgctttc
    44461 gttttgggga tcttatcgac ttatgtttta tggcttgaac catttgccgt agctttggtt
    44521 gctttttcca gcagattcgt gttgcgatta ttccatattt ctaaaccagg tggcttgttt
    44581 tttgcgatgc tttctgccat gggaacgagc atgcagctgc caatcgctca attaccgatc
    44641 gtctcacttt atttttttat gggtgtcgtt tttgccctga ttgcggcagt gattacaaaa
    44701 ttactggatt cacggcctga gcagacaatt gaaaaagcaa ctttaaaaga aagatttcac
    44761 gaagagcctt tagtgatcat tgattctgtt ttctacagcg ctgccttatt tctttccgtt
    44821 tatgtcagtc acggcttgaa tctgcataat ccttattggt tgaccttgtc atgtgcatcg
    44881 attttgctag cagaaaactt ggatgcgatg aagcatcgac aagtccaata tctgattgga
    44941 tcgatgggtg ggttatgtgt gtcggcattc ttgtcatttg tgccgtttac gcagttgcag
    45001 accatttttc tgatcacttt tctatatgga atcgcacaat ttctagttgc tagaaattat
    45061 gcagttgcta atatttttct taatccgatg gcgttgatgc tatctacact tattcgtgga
    45121 gcatacttga tttctttgat cgaatatcgt tttttaggga tcgtcatagg aagtttcatc
    45181 ggtttaggtg ttgcgtgggt aatgacggtt ggtttgcaac attatttaac ggttgttcgt
    45241 caaaaattag aatagaagga caaatatatg tgccaaaaga ggttatgaca agatttttgt
    45301 cacaacctct aattcaaggt gttcaaaagc cagattctca gcattaagtc aaattcacac
    45361 aaaaatgtgg aaaggaactt tcaaaaaaat tttatattta ttctatcaaa aaattttgtt
    45421 tatgatggta actgaataaa ctttcctgag atggtcaatg ctttccttga aagtcttaca
    45481 gatattcttt cttcatagaa agtttaagtt ttatagttag tgtacaataa aagtatgttt
    45541 ataccatatg gtgtccggat aatcagtcat ttaaacaatg aggttcaaag atatgaaaag
    45601 gggaaatttg atgaagaaaa taagcaatga aatccaaatt ctggcagaaa ctttaactct
    45661 tcccaaagtc gttatagagc aaatgattgt acaagcaaaa aacatccttg atgaggtgtt
    45721 tgagcaatat agtcatgaac taatggatcc taataaagca aaggcgactg caaagaaaat
    45781 agacaaagtc tatgaagagg aaccttttgc agcattagct atttatctat atgcagcttc
    45841 tcaaagttgg aaaaaaattt atcaaccatt gaagattcca agaactatct atttggcaac
    45901 aatgaatgct tttactagat ttattcatga acatttccaa gtaacaggaa gctatcgctt
    45961 tgaccgtggt ttttggattt ggcattacac tagtggcttg atctttcgga ttggtgaatt
    46021 ggagtacgaa atgacatatt ttccgaaagg gtacacggat ctaagattag aaggaaagca
    46081 gtgcctttct cttcatattc cttccgatgc agatttatct cagaataaga taagagatag
    46141 ttacgaaagt gccattcgtt tttttgaact ttattttcct gattaccatt accaagtgat
    46201 gtacacagat acttggttac tatcacccaa tcttactaaa tggttgaaaa aagagtcaaa
    46261 aatctgtctt tttgcagccg attatcgatt attatcagtt gatgaacagg acgatagtgg
    46321 agtcccttgg atctttggac gagtagatgc ccaaatacat gattatccag aaagtacgag
    46381 tttacagcga caagcaaaag agcaattgct tgcaggcgag cacattggct ctggcttagg
    46441 tattcttact tcataagttt agtacttcga aatagtttaa aagagcgtga gacaaaagta
    46501 aagaacactt ttgtctcacg ctctaaacac gtataaacgg cggaagcaga agcaactcct
    46561 tcggaaataa gctgaaattc acaaaaattt gaaaagcaat tttcgtgaat ttcttcttat
    46621 ttcttggagt taaacgcttc tgtcccagcc tcttttttag tgttctatcg aacacacagt
    46681 acgttcaata ggtaaactag ctataacaat agatattaaa gttaacggac aagagggcct
    46741 tttttaggta gctaaaacgt aataatgaaa atttatttcc agagatagga gtcaatcagc
    46801 tagtctgatc gactgtttta acaagttgac tttcatttta acttttgata ccatttaaaa
    46861 cacaaatcgt aattgtttcg atttgtgttt tttagcatga ctacaatcaa agaagaaagt
    46921 gggtcgtcca tatggaaaaa acagatatct caagtgcata ccgccgcttg aaaagcccaa
    46981 atatcaaaac acgaaaacgt gcgctgaaga tcatcaaaga tgtgaaacgg aatagtggga
    47041 aaaggtaaga agaaggaaac ttaattaaaa aaatagccga aaaacgtttt tcggctattt
    47101 tcaataatcg gtttttgtgt aaggtttccg aaagaactgc tgttgatttt ccatttttaa
    47161 catatgataa attggtagaa tctttctttt caaattgata ccattcccta attccagtta
    47221 tatagttaac tacagaacca caaagcacgt acgtttataa aagtattatc tgtagttatt
    47281 tttcaattcc ctttcaacct cttattttga ccagtagtat tgatcacttt accttttaac
    47341 acctttgttc gtttttgaaa catttttagt caagaatgga aacgtaacta cataatcaaa
    47401 ggttttgcga aatatttcat gaaatatttc atgtagaagc gagcaatacg gttgcaaata
    47461 accattatcg tttaataagc agttacgaaa gctcccaata tctctaacgt tcagctcact
    47521 ccatttcttt tcttcaaaaa aatcagtgat tcgtatctct ttctatttgt cgaaaaagtt
    47581 aactttaaaa agtaacgccg aaaaaatatg caaaaaaata aaaaagcagt tactattgct
    47641 agaataacat caaggaataa taagttttgg ttttcagata atagtcgata agttgtgtat
    47701 tggaatttta gatacagtaa taaagtattt ttcatgaaat tttgtgagaa tcactattac
    47761 aagtatcttt aataaaatta atggttaagg aggaacttaa agtagaatgt aaatgaatag
    47821 ttgtagtcag tcgattgtga tactagactc aaagttgcag gaataagttt ttcaatttgt
    47881 gattggaaga taaaaaatga aaaagaaggg ctttttttta tactttgttg attgtagtgt
    47941 ttattttccc tctgtttagc caagtaacat tttctatgac tcaaccagtt tcaagtgagg
    48001 aacatgataa cctttttcgt gctacagaag agtttaagaa atatcaggaa aatattgttc
    48061 cggagactcc attagctagt gagccaatta ctgatattga tggaaaccaa ataggatggt
    48121 atatacagta cgaagttatg gtggtaaata atgactcaat agtaaaaaat acagtaggct
    48181 tagagctaac accgattgaa aaggtgagtt cattgttaac gtatatttat actgatgaaa
    48241 gtgacgagac tgagatcatt ttaacggatt actcaaaaat tgctactgat aaaaagtata
    48301 tattgtggat gtagacacta gtgaaatact ttatgatata gaaattgatg aaaatttact
    48361 agatgtagca caagaaatcg atcatcaaaa gcaggaagct attcgatatg ctggtagaaa
    48421 agggaaaaga aaatatttat tacgtgaatg tagcaaaagt tagagaagat gaaaatgagt
    48481 ggaaagaatt caagagtcgc tactcaatta actcgactcc gacatttaca gtttacagag
    48541 aaggatcgat agaaaaaact gttttttgga ctaaagaaag tggaatgtct ttagctgaag
    48601 tagaagagtt tttggattat gttagtatgc aacagtaagg gagttcttat tatgaaaaat
    48661 tttgacacat attatgttat tgttttttcg atatctttgc tgttaatatt actaacttta
    48721 atgcagtata aagagtatcc agagtatttt attttaactt ttgtatattt agtaagtagc
    48781 tacacacttc tatataaatt cagaagttct tctagagttt ctaaagtttg tttcttaatt
    48841 agcttattga ttctataata tttttgattt atataggaaa ttaaaaatat tatagaatca
    48901 acactcagag aacgggttgg tttttaatag atttaataag tactgataat gaaatttctc
    48961 ctggttggga aaacgaagtt ggttaccctg tagaagaatt ttttcaagat tactttgcgg
    49021 agtatgccga taggataatg agagattacg taacagataa aactcaagaa gtcatcaatc
    49081 aatcccagtc attaaatgaa ttatctgata aggcgaaaga agaagcagtt gccattattt
    49141 cttcagggat tagtgactat attgatatga gtggtgaaat caattatggc gataaagaca
    49201 aaattgtacg catgataaaa gcttttatca aaacttttga tgtgaaggca gatcttaagt
    49261 ttaatgatac ttacctagta ggaaaattaa ttaatatcct tgggacagag aaagatacgg
    49321 aaacgtttat ttcctctttg tctatgttgt ttacagataa gcatttttca actcagcttg
    49381 gtggagagga actagtggaa atcttttaac cattacgccc agcattaata aaagtatatc
    49441 aaaaaagtac tcctgatgat ttttaagatt ggtttgagaa ataatgtgaa aacactattt
    49501 ttaatgttaa ttatagatag agatgaacgc gtcatatggt taaaagaatg aaaaagtcaa
    49561 agatacactg ctatatttca ctaaggatat agcagtgtat ctttcatgtc gtttcactgg
    49621 cagtttttta taaaaggagg tgtgcatttc agttgctttt ctttggtagt tagttgaatc
    49681 gtttaagaat taacggatgt ggcagacagg tgctctgtcc aaaaaccagt aaaatctttg
    49741 atggttccat ctttatttag ctgtgcctgt tcaaatactg ttttgttttt accgaatgga
    49801 tcaattgcaa taattgttcc gatccccgca cgtttggcag caagtaatcc tgagtaagca
    49861 tcttcgataa caagacaatc agccggagct aagctcagtt tgtctgccgc tttaagaaaa
    49921 atatccggtt gcggtttccc agggaaagag ccgtcgtcat agacaatctt gtcccagtca
    49981 aaccagcggg ctaaatcgaa aatatcaaaa taaaaagcaa cattctcttt gacagtagcc
    50041 gtggcaatcg ttaatggaat ctgttggtca gtcagctggt caagagtcgc ttcaagccct
    50101 tttgtcaact gaagctcgtt ttcattttgc aagcaaagca tacgataata gctttctttt
    50161 tcttctgaca atacggcgat ctcagaggcg gtcaaatgct ctgaaatgaa atgtttcaaa
    50221 atctccgtat tcgtccgacc atgaatattt tttaaaatat cctcgtctga taaaccatct
    50281 tttgtatgat catgtatcat atgcagccaa gcagcttcat gcagatgaga gtccaaaaac
    50341 attgttccgt tgaaatcaaa tataatccct ttcatagtta cgctcctata gtggtatttt
    50401 cggttgaatc agcaatttgc agatcgacat attgtgcata gtgctcttga acctcccgcg
    50461 agatctggcg atccgtaatg agcagatcga aatcatgcaa attataaaac acataaaaat
    50521 catctcgatt gaatttttta ttatcaacga gtagatattt cttacgggaa ttatttagag
    50581 cgatctgctg tgcttctcct tcttcggtac tgtaagtaga gatcgcttcg ttgtgaacgc
    50641 catttgaact gataaatgct tttgtaaact ttagtcttct taaattgtcg ttggtgatcg
    50701 gtccgacaaa tgcgccggta tttttccgga aatcaccgcc aatcagtaga atttctggtc
    50761 catctgcttg agcaagaata tcaaaaactg gataattatt tgtaatgatc cgaattttct
    50821 tgttcagtaa atgcgtcgcc aatagttcga ttgttgtacc tggtcctaag aaaatcgttt
    50881 ctccctcgtg aatcaaggag gctgctgtgg cagcaatttc ttttttttct tgaatctgca
    50941 gagtggcttt ttcagtgtga gaaagttctt gatctaaagt gtaggaaaga ctttgagccc
    51001 ctccatggac acgcagcagc ttgcccgatt tttctaattc atctaaatct ctgcgaacgg
    51061 tcatatcaga aacatctaat tgattgatga tttcattaac ggtaaggatt ccttttttat
    51121 tgaccatttc tacgatagta agcaatcttt cttttttcaa cattgtcttc acctctaatt
    51181 taaggataat ctatcatata aacggacaac agtcaatcta attcgaacaa aagtaaacat
    51241 ttagggtggt ttttatgttt gttacaatag attttattgc tgttttctgg tttttatgat
    51301 tatttgtgtt tgtttttgtt gacaaatgtt ttggatgcgt ttacaatgca atcagttaga
    51361 aagagcgaaa actgattata gatttgagga gagatgtaca tgcttaaatt accagaagat
    51421 tttatttttg gcggagccac agcagcctat caggttgaag gagccactaa ggaaggtggc
    51481 aaaggcgctg ttgcttggga tgacttttta gaggaacaag ggcgattcag tcccgatccg
    51541 gcaagtgatt tttatcatca atatgcaaag gacattgaat tgtgtgaacg ttttggtgta
    51601 aatggtctaa gattatccat tgcttggagc cgcatttttc ctgatggagc tgggaaacca
    51661 aatccagaag gaatcgcttt ttatcatcgt gtgttcgaag aatgtaagaa aagaaacgta
    51721 acgccgtttg tgacgttgca tcattttgat acccctaaac gtttgtttga ccatggagat
    51781 tttttgaatc gagaaacaat agaagcattt gtttcctatg ccattttttg ttttcatgaa
    51841 ttcaaagaag tcaaggtgtg gagtaccttt aatgaaatct atccagttgc aaccaatcaa
    51901 tatttgttag gtgttttccc accaggaatc aaatatgatt ttacaaagat cgtcgcctgt
    51961 cttcataata tgatggttgc tcatgcccgt gtagtgaact atttcaaaga aaacgaactt
    52021 ccgggtgaaa ttggtgtagt tcactcatta gagacgaaat atgcggcaac agacgcgccg
    52081 gaagataagc atgctgcctt tttagacgat gcattgtcga tccgtttctt attagatgct
    52141 acctatttag gctattattc aactgaaacc ttgactgctc ttgatgagat atgtgaagca
    52201 aatcaggcca gctatcattt tcctgaagaa gatttcgttg aattgaaaaa agcatccacg
    52261 cgtaatgact acttagggat caatcactac caatgccatt ttgtcaaagc ttacgatgga
    52321 gaaaatgcaa tccatcataa cggtacgggt gaaaaaggga cctctgttta taaagtgaag
    52381 ggaatcggag aacgtattta taaagaagga attcctcgaa ctgattggga ctggctgatt
    52441 tatccagaag gtctatatga cttgttgctg cgaattaaaa gcgattaccc acattacaac
    52501 aaaatctata tcactgagaa cgggatgggg tataaagatc agtttgaaga tggcattatt
    52561 atggatcagc cgagaatcga ctatttgaga gtctatttgg aatccttaag caaggcgata
    52621 acagccgggg taaatgtgaa ggggtatttt ttgtggtcgc ttatggatct tttctcatgg
    52681 acaaatgggt ataacaaaag gtatggcttg ttttatgttg attttgaaac ccagaagcgt
    52741 tacccaaaag aatcagctta ctggtacaag ttggtcagtg aaaccaaaac gattatttaa
    52801 taagtgataa tggaggaaga aaagatgaat aaagaggaat tacaaatgct tggttttgag
    52861 atcgttgcat attcaggcga cgctcgcagt acattattga aattattgaa agaagtaaga
    52921 caaggaaact ttgaacatgt tgattcggcg ttgaaagaag ccgacgaaaa tttaaccctt
    52981 gcacataatt cgcaaacaaa aattttagcg gaagaagcat ctgggaaaga gatggagatg
    53041 ggattcattt ttatccatgg gcaggatcat ttaatgacca ctttattgct gagagatctg
    53101 attcaagact ttattgtact gtacagacag aatcaaggat aggagaagaa cgctatggat
    53161 ggaatcatta aacaaatcga aaaagggaaa ccattttttg aaaaaatctc acgtaatagt
    53221 tatttaggag ccgttcgtga cggattttta acagcgatgc cagctatttt attttcaagc
    53281 attttcattt tgattgctgc ggttcctgag atttttggtt accaatggcc tgaatctgtc
    53341 tccacatggc tatggaaagt ctataattat tcgatgggtg ttgtagggtt actcgtttca
    53401 gcaaccactg ctcgctgctt ggctgattcg atgaatcgtc gcttaccgaa aaacaaagta
    53461 atcaacacca cctctgtgat gctggcctct gtggtaagtt tcctgttgtt aagcgtctct
    53521 ccgattgaag gtggattttc aacggaatat atggggacaa agggactact ggcttccttt
    53581 gtcgctgcat ttttaacagt taatttatat aagttttgtg tgctgaaaga tattaccatt
    53641 aaaatgccta aagaagttcc tggaacgatt tcgcaaacct tccgagatat ttttcctttc
    53701 tctttttcag tatttgcggc cgttttaatt gatttaggca ttcgacaaat cttccaaatc
    53761 tcatttgcag aagcaatcat tacggtgctg cagccgctat ttacagcagc tgacgggtac
    53821 ttaggaatcg ctattatctg gggagcgatg gcgctgtttt ggtttgtcgg tgttcatgga
    53881 ccgtcgatcg tggagccggc aattgcggca attatctatg ccaatgtgga aaccaatctg
    53941 caattgttca attccggtga acaagcttct aaagtactga cggtgggttt agggaatttt
    54001 gtaggaacta tgggaggaac tggggcaaca ttggttgttc cttttatctt cctactcttt
    54061 gctaagtcta agcagttgaa ggcagttggg aaagcttcct ttattccagt aagtttcgct
    54121 gtcaacgaac cattgctatt tgcggcaccc atgattttga acccttattt ttttattcca
    54181 tttttgttaa cacctgttgt aaacgtttgc ctgttcaagt tttttgtcga tgtattgggc
    54241 atgaacagct ttatgtacgt tttgccttgg gcaactccag caccgatcgg tttggttcta
    54301 ggaacgggca tgggtatctt agcttttgtt ctagcagcgg ttctaatcgt cgttgacttc
    54361 ctgatctatc taccattttg caaagcatac gatgctgtct tagtagagaa agaagcacaa
    54421 aaagcagagg tgatcgcaac cgaggaaggt gcttctgccg atgtacgtga ggaagtacct
    54481 gtggcagcga gtcaagttat cagcgatgca aataaagaaa tcaatgtgtt ggtactttgt
    54541 gctggcgcag ggacaagtgc gatgttagct aatgctttaa aaaaaggtgc atctgaatcg
    54601 aaagcaccga tcagtgcaat ggcgggtgct tatggttctc attacgaaat gctgcaggat
    54661 tttgatatgg tggtcttagc accgcaagtc aattcttact atgatgatat caaagaagac
    54721 accgatcgct taggaatcaa gctggttgcg acaaaaggag cagaatatat cggattaacg
    54781 agagatcctg aaaaagctgt tcagtttatt ctgaaccaat ttcaataaag gaggagccat
    54841 aatgaaaatg ggaatttggt tgcgtaaagc tgttttattt gcagctgtgt taggggcttt
    54901 gggggctgtt tcaaaaactg ttgaagcatc tgccagcgaa tttattcgcg gagcagatat
    54961 ttcgatcctg tcagatatgg aaaaatctgg tgcaaaatat tatgaagacg atatttcaaa
    55021 agatgcctta gagattttaa aaaataatgg tgtcaactat gttcgactgc gtttgtggca
    55081 ggatccttat aatagtaatg gagaaagtta tggagcaggg acaaatgatc tggaaacgac
    55141 gattgacctt gcaaaacgag caaaaaatct gggacttaag gtgctgctgg attttcacta
    55201 cagtgatttt tgggttgatc ctgggaaaca gaatcttcct aaagcatggc aaggtctgac
    55261 ctttgaagaa atgaatacgg cattgtacga ctatacaaag aacgttctgt cggaaatgaa
    55321 gcagctggac gtttatcctg atatggttca gatcggcaat gaactgaata gcggaatgct
    55381 ctggccttat ggcaagtctt ggggagaagg cgggggagaa tttgatcgat tggctgcttt
    55441 tttgaagtct ggtatccaag ctgttcgaga cactcaacct aaaacaactc cagtaatgct
    55501 ccacttagct gatggtggcg atacaggagc atttacttgg tggtttgatg aaatcacgag
    55561 tcgaggtgtg tcatttgatt taattggagt gtcgtattat ccgtattggc acggttcaat
    55621 gaatgaactt caaaccaata tgaatgcgat cagccaacgg tatggtaaag aagtgatcgt
    55681 agttgaaaca gcttatgggc atacaacagc gaatgccgat actatgccaa atgcttttgg
    55741 tgaagccgaa gcagctgcgg ggggatatga accaacaccg acaggacaag cagagtattt
    55801 gctggatctt gccgatcgga ttcaggcagt accgaataat cgcggggcgg gcttcttcta
    55861 ttgggaacct ctttggtaca acggaaatgt gagttgggca acacaagcag gtatgaatta
    55921 tctcagtgtt caatccacta tgggaaacga atgggacaac caagcgatgt ttgattttgc
    55981 tggaaacgcc ttgccaagct tgcgtgcgtt taaacaagca ggggcgcaaa taaatctagt
    56041 taaaaatgca agtttcgaaa gcgatggacc aacgaccagt ccttccaatt ggcaaacctg
    56101 gtttcaacaa ggaaccgcta agggtacgat caaaacggaa gcgggcactt tttttgggga
    56161 ctacaaacta actttttggc aggatcaagc atacgaggca tcagcttatc aaaatgttag
    56221 tggcataagc aaaggaactt acacattgag tgcctatgta atgtctgggg gagagtttga
    56281 tactaatcag ttatatatca aaaattatgg tggagcggaa ctaaatactg cggttgttaa
    56341 aacaagtgaa tggacaaaaa ttacaatcaa agacattcca attacaacag gtgtttgtga
    56401 aattggggtt tatagcaagg cttcaggaaa tgcttggacg aacgttgatt ttgtttcatt
    56461 ggtgaaacaa tagactgcgg atcgtttcga ttcaagatcg gaggttccct tcagccacat
    56521 cgttagcgta gaaggcagga atcgaacctg cacctcgcct ttgccaaaaa taaccagaaa
    56581 cgatttccag tcatttttac caaaacgagt aaagcaccag acttcatcta cactttgtat
    56641 tatgctaaag agagttcaac gatttcgtaa gaagcaatga aaaaattgca aaaagttgtg
    56701 cagataacat aaagtttgtt taagaaaggg taaccttaga attccgtcgt gaatatgatt
    56761 tgagcactta gatggataga aaaaagttct cggaaaacag ttcgtttttc gagaacttct
    56821 ttttatgata agaatgaaac aaattaactt atattatagt ctcttttggt agggaaccat
    56881 cttattttta atgaaaatca agcattttag ctattgaaga atgttgattt atagggattc
    56941 cccctccata ttatgttggc tctttattcc cactctgttt tcaacgtaaa gtgtataaaa
    57001 cagaatgcga tactatcaag ggagttaaaa caatatacag aacagtaaaa cactataaat
    57061 aaaaataaaa gtgcaataaa agtgcaattt ttgcacctaa tcatactctg tttatatatg
    57121 aaaactagat tctgaatcca atatttggtt aacgagaggc gttcgaattt gaacgtcttt
    57181 tatatattac tttcaaataa atatgaggta gaatactatc tattttcttt ttaacccaat
    57241 tgttataatg gagagtgtaa aatattttgt gtaaatagaa aaaaggaagt cccttctgta
    57301 gaatagagtt accacaacac attcacagaa gagaggactt ccctatgaac gattttacta
    57361 cagaaattct aaagactcta gcgaacaaag gcgatttgaa tgaattattc cgtgtccatt
    57421 tggagaaagc agtcaatacg cttctcaaaa cggagttaac ggctttccta gattacgaaa
    57481 agtatgatcg cattggtttt aacacgggta attctcgtaa cggctcctat gaccgtacgg
    57541 tcaagaccga gtatggggaa cttcatctcc agattccgcg cgaccgcaat ggtgagttca
    57601 agcaacagac tgttcctgct tatagacgga cgaatgacac gttagaggag accgtcattc
    57661 acctcttccg aaaaggtatt accatgtcgg aaatcgcaga cttgattgag aaaatgtatg
    57721 ggcattacta cacgccccaa accatgtcca atataacaaa atcatttaca gaagaggtaa
    57781 cggcgtttaa tgggcgggag cttcatgacc gttatgctgc tatttatatg gacgcaacgt
    57841 atattccgtt aaagcggaaa accgtcgcca aggaagctat tcatatcgca gttggcattc
    57901 gcccggacgg atcaaaggaa gtattgagct atgcgattgc accgactgaa tccatcacga
    57961 tttgggagga aattttattg gaccttcaag agcgcggttt gaaaaatgtc ctcctgttca
    58021 tcacggatgg cttaaagggg atggtaggag cgattagtcg gttctatccc aaagctcgtt
    58081 ttcaacattg ttgtgtacac gtttcccgta atatcagtca taaagtgcgt gtcgatgatc
    58141 gtaaggaagt ctgtgatgat tttaaaatgg tgtatcaagc ctcatctaaa gaggtggcgt
    58201 tggaagcacg tggtactttt gcggaaaaat ggaaaaccag ctatccaaaa gtggttgaat
    58261 cgattctttc gaacgatcac ttgctcactt tctatgattt ccccttggcc atacgcaaga
    58321 gtatttattc tacgaacttg attgaatcct ttaataaaca aatcaagaaa tacagccacc
    58381 gcaaggaaca gttccaaaat gaagagtcga tggaacgttt cttagtctcg tcttttgata
    58441 cttacaacca aaaattccta ggtcgcagtc ataaaggttt ccaacaggcc gaaggcgagc
    58501 tcgaacaaat gctaagccaa ctgattgaga attagaaaca atctgcagta gggaagaatc
    58561 atttacacaa aattattgac gctcccttat aatgagaact tttactaaca taatttatga
    58621 taaacttact atataatcat attaattaaa tagttaggag atctgcttat gtttatatct
    58681 actcttcaaa ttcgaaattt tagaaattat gaatccgaaa tctttcgatt cgataatgag
    58741 acaaatacta ttataggtga gaatgattca gggaaaacca atgctcttac tgcattgaga
    58801 atcttattag atgatagtta ttactatagt agtaaaacac taaaagaatc agattttttt
    58861 catggaattc aaaatgggtg gcaagggcat tggattatta tctctgcgac atttgaagga
    58921 atcagcgaag aagaatttga caatgagatt tgtgcttcca tttctttaaa ttctgaaagt
    58981 caaacaatct tagaagaatt gatttcaaat gcagataaag gtgtaggtag tatttctcta
    59041 tttattagac ctaacaaagc tattagaaag caattatttg atatttccac tgaattagac
    59101 tctcatcaat ttaacgaatt tagaaattct attcgtctat ccgactatga attttactac
    59161 acatctaaat caaatctaaa tttctgtatc aatgaaaatt atgataaatt ggtaggaaga
    59221 ctcaatgaca atatagctag taatcctgaa gaagacgatg aagctctgtt gggctcaaga
    59281 attgacatgt cagatatttt caagcatatt tcggttgttt atgttgacgc tcttcgagat
    59341 gttcttagag aaatgaaaaa caatcgaaac ccagtcaaaa gaatcatgga aacaattgaa
    59401 tcaaaaatat catcagataa tgttgagtca ttaaaaacaa ttatacagca attaaatgag
    59461 actattacca gtgttcctga aattaggaaa attggcgaaa atattaatcg gcaactaaat
    59521 agcataattg gttcagtgta ttctcctaat cttcttcttt cctcaactat gtcagatgat
    59581 atgggttctt tagcaaaatt tctttcaatg aagccagaac aaaatatcga cttagactta
    59641 ctagggttag gacatctaaa tatgatttat ttagctttga aaatagtcga atttgaagcg
    59701 tgtcgttcaa gagaactact taatattatg ttgattgaag aaccagaagc tcatattcat
    59761 catcatattc aaaaaactct gttcgaagga ttaaatcttc aaaaaaacta tactcagatt
    59821 ctcatgacca cacattctgt acatttagct gaagtgtctg aaatatctcg gatgaatgta
    59881 ttaaaatcgt ttaatggcaa atctatcgtt atgaatccag caaataatct gaactcattt
    59941 gctaaagaaa agttaaaaaa gaacaatcta aatctaataa acgcagtaga gagatattta
    60001 gatgttaaaa gaaatggatt gcttttttct aaaggtgtta tcttagttga aggagatgct
    60061 gaagaaatac ttattcctca aatagtaaaa aaattatttg gtataaactt agacgaactt
    60121 ggaataggtt tgattaatgt tggtagtact tcgtttgaat atatcgctag cttgtttgac
    60181 gatgatagaa tacagagaaa gtgtgctatt gtaactgatt tagatgaaca ggcaatccca
    60241 tcagaacatc gattgtataa aagcactgca caagagaaag gtcaagcaag aaaagaaaaa
    60301 ttatcctccc tttttaatga aaacaattgg gttaattgtt tttatgctaa tacaacattt
    60361 gaaattgagt ttttagatgt gaataaagaa aatattctaa cttatgtcag tccaattata
    60421 gatgacgcat tcaaagataa aaaaacaata actgcttata aagaagaaat acaaagtgaa
    60481 caatatttag aaagaaattt agcgatgtta aaactagcca atcatgttgg taaggggtgg
    60541 tttgcaattg agttaggtga aaaaattgac tttttaatca aaattcctaa gtatattctt
    60601 aatgctattg cttttgcatg tcaggaaata gtagatctct caatttataa aaaaattcta
    60661 ctccatacaa tcgacttgta cgaggaaact acagaattgt cagctttatc agctagttta
    60721 aaaacaagtg atacagctga tttgaatata gcaataattt ctttattaga gtactttggt
    60781 aaagatgagg atgttgtgta tctaatcaat cagatagaaa attacacaaa aatactttat
    60841 gctgaggttt caaaatgaca aatatcttcg aaaaaatcgt aaatgattta aatttagaac
    60901 aaaaagatgt tgtggaaagt gaagataacc tttatgtaaa tgcatgtcct gggagtggga
    60961 aaacaagggt acttacaagg aaaattgctt accaagcaat taaacacgat ggatcactaa
    61021 aaagaataat tgctatcaca tacactaata gagctgctga agaaattaag gaacgcctaa
    61081 gtttacttag tatagatgat gatattaata tttgggtggg gacaatacat cagttttgtc
    61141 ttgaatttat tatttatcct tttaaaatga atctctcaag agtatcaaaa ggatttacaa
    61201 ttattgatga ttatactcaa agagcttacg tcagccaaat taataatatg ctgaatttaa
    61261 atctcaaaac gtatgaactg aacaaaattg atttgtcact ttctcatgat tttaaaatta
    61321 atgaagttca gtatactcaa gtttctgaaa tgtatcacac tatgttggaa aaaaataaag
    61381 aaattgattt tgatatgatt ttactagtag cgtataaaat tttaactgta aacagtaacg
    61441 ttgcacgtaa tattgctagt aatataaggg cgatttatgt ggatgaattt caagatacta
    61501 gagaattaca atacaatgta atagctaaat tacttcaaaa caaccctcaa attcagtcaa
    61561 tgtttgttgg agatattgac caagcaattt atggatcatt agatggtata gctaaatcag
    61621 ttgaagaact agaaatgcta actagtcaca cttttcaatc aaagacgcta catggctgtt
    61681 acaggtctaa tcagagatta gtagacttct actctaattt tcagagttgt ccttacgaga
    61741 ttgaaagcag agggaataat aaaaacgacc gtggttttat aagttatgat tgcaaagtta
    61801 ctaaggagga tttacccaac ataataaaaa atataataaa ggaaaagatt gaaagcggca
    61861 ttcatgaaaa agatatttgt gtacttgctc ctcaacacta tcctctgttt tcactgggtg
    61921 agtatttaaa gaaagaatta ccgtattgca attttgatgc tataaatata tcaccaatta
    61981 aggtaaataa tcatagttta tttttcaagt tagcaatttt gtactttact gaatcaggtg
    62041 aaaaggttcg aagaagaaag ctaattgcaa acgatatttt aattatatta aaaaatgaat
    62101 ttggaataga agttaaagat tattttattg acttagattt attacagcta ataaacagtg
    62161 tgaaaagaat gtatagtgga gacgacaacg gtgttgattt atacaaattt gttaccaaac
    62221 atatatttgt taatcttaat attgacgaga aaaattaccc gtctattttt aagcactatc
    62281 tattttttat taacgaagta gaagatcgga taaaaaataa ttcattatct agtagtgtat
    62341 ctagttttaa gaagatgttt aaatctcgag atggtatcac acttactaca gcacataaag
    62401 ttaaaggaaa tgagtatgat actgttatcg ctattaatct tctaaacggg aaaattcctc
    62461 attggaatga aatttttaat gtttctgata aaggaattag ttcagcgaga aaactactat
    62521 acgtaatttg ttcaagagca aaaaataatt tatttctttt ctcagaggtg ggttatttta
    62581 cgagtaaagg agacttgctt tatcccactc aattattaga taaaatagaa tttgattata
    62641 atatttaaaa tacctaggta gtcgttgttt taaatatagt aggaatcgga cgctcagtac
    62701 ggagcgtcta tttttttacc caattttgaa aggaagtgaa cttatgaaaa taaaaaatca
    62761 agaatcaaaa ggtcgctctc ccccctttaa aaccatcaca caaataagat tcattcaaac
    62821 ataaaaacag aaaggatagg taaaaatatg gaacttaaat atgtcattcc caatatggaa
    62881 aaaacatttg gacaattaga atatgctggt gaagggaaca ttgaacaacg tcgaataaat
    62941 ggcagaccaa ccattctctc tcgtagttac aatttatact caacgattca acgagcagat
    63001 gatattgttg tcattcttcc ctccgaagct ggcgagaaac attttgaatc cgacgaaaaa
    63061 gtcaaactca tcaacccaca tattaccgca gaaggttata aaattggcaa tcgaggattt
    63121 accaattaca ttatgcacgc agacgatatg gtgaaagcat aagaaaggaa aggtgaaaaa
    63181 atatgagatt agcagaaggt attgtgattg aaaaagacca gacatttggc acattgaaat
    63241 tttccgcctt gcgtcgtgag gttcgtatcc agaatgaaga tggtacggtt tccgaagaaa
    63301 ttaaagaacg tacctatgac ttaaaatcaa aaggacaagg acgcatgata caagtcagta
    63361 tccccgcttc tgttcctttg aaagaatttg actacaacgc agaagtggaa ttaatcaatc
    63421 ctgtggcaga taccgtagcg acggctactt ttcgaggggc agacgttgat tggtacgtga
    63481 aagcagacga tcttgtatta aaaggacaga caaaacctca tcagaaatat aaaaaagaag
    63541 cgtccgaaag tgaaaaatag gtgttgctta tgacaaacac accattgatt ttgaaagaaa
    63601 ttccgaagga tgaagccatt tcttttattc ggcaatacca ttattcaaag atactcccta
    63661 gattgtgtaa atactttcta gggatttttt cagaagaaaa attattaggc gttgtggaat
    63721 taggctgggg tacgcaaccc ctacaaacca tacgcaaact ctttcccgac agttcccttc
    63781 aaaccacaga ttatttagaa attggaaaga tgtgttttct tccagaaatg aatcaaacca
    63841 attattttgg cagtcaagct ctttcagctc taattaagtg gttgaaagaa catacggact
    63901 gtcatttttt atatacactg gcagatggaa ttgagggaaa atgtggctat gtctatcaag
    63961 cgtccaactt cttttactgc gggtatttca agacaagtgt ctatcgtgat aagcagtcat
    64021 gggaaaagat acaccctcga agtgctcgcc ttttattaga ggaaaatgct cgctttgaac
    64081 aggtagagaa aaagcattgg ctttcccagg cattttgcga atacaaaggg attgagaaaa
    64141 tcaatggacg catgtttcgc tatctctatc cgttgacaaa agaagcgaaa aaactgttag
    64201 gacacactct ctatcgacgt cattattatc cgaaagaaaa aaatttacgc tttgaaaagc
    64261 gaatcgctta tcagaaatat gaagccattt ctcaaccaac ttttgataaa caggctcgta
    64321 tctacaatac acaattattt tgataggtgg aaaggaggat ttttatgcca ttgcttcatg
    64381 acagaggaga gcgaatcaaa gccaacgata agcacttggt ctatcatttt gtactaattt
    64441 cattgctggt agtttttcta gtcgtcctac tcccttttca ttggagagcg ttacaatcgg
    64501 tgaactggca agcagttcag ttagatacat ttttctatca acttcatacg ccatactttt
    64561 ggagcagtat tctcactgct ctttttgtat gcggacttat cagctggctt tattatcact
    64621 atcgtataga ttctataaaa cagttagagc accgtcaaaa gttagctcgt atgattttag
    64681 aaaatcattg gtatgaagcc gaagaaactc aatcagaggg attctttaaa gatttaccca
    64741 gcaagaaaac caaacaacga atccgccatt ttcctaaaat atattatcga atgaaagatg
    64801 gactaatcca tattcatgta gaaatcacct tagggaaata tcaagatcag cttttgcacc
    64861 tagaaaacaa actagaaaca ggattgtatt gtgaattagt ggaaaaaacg ttgaaagatt
    64921 cttatgtaga gtatgtccta ctttatgata ctattggcaa tcgaattggc attgaagacg
    64981 tggtagctca agatggacgt gtcaaattga tggaatcggt ctattgggag ttcgattctc
    65041 tccctcacat gttaattgct gggggcactg gtagtggaaa atcctatttt attctcacat
    65101 tgattgaatc tctcctgcat acaaatgcaa agctttatat tcttgaccct aaaaatgctg
    65161 atttggcaga cttaggggcg gtcatgaata atgtctatta ccgtaaagaa gatatgttgg
    65221 catgtatcaa tcaattttac gaagatatga ttgatcgcag tgaaaccatg aaacaacacc
    65281 ctaactataa aacaggagaa aattatgctt atcttggttt gtctgccaat tttcttattt
    65341 ttgatgaata tgtggcaatg atggatatgc taggtcgtga aagtaccacc gttattcata
    65401 aactcaaaca aattgtaatg ttaggacgac aagcaggctt ctttttaatt cttgcctgtc
    65461 aacgtccaga cgcaaaatat tttagtgatg ggattcggga caactttaac ttccgtgtgg
    65521 ctttgggtcg tatgtctgaa atgggctttg gtatgatgtt cggaagcgat acacaaaaac
    65581 aatttttctt aaaacccatc aagggaagag gttacgtgga tacaggaaaa agtgtgatta
    65641 gtgagtttta tacacccctt gtaccaaaaa ggtacgattt cttaggagaa ataggaaaag
    65701 tcattcaaaa aaagcaatct gagcctgtac cgcacgaagt gaaaggtaca ggttcagact
    65761 tgctttgatt ggtgtggcgt tagccacgcc aatcctttag ccccctctat ctaacagggg
    65821 ggcacaaata caactgaaaa caggcaattc tcatcaacca atgttgatgg tacaaaggat
    65881 tgcggaaaat atgaaaggtg taaactcaag ggtcatagtt tacatctttt ttagattgga
    65941 ggtttgcgaa tggaaaacga aaaaatttgg attaaggaat tgaaagaaaa gcgactggct
    66001 tatggcgttt ctcaaaataa actggcggtt gcttctcata ttaccagacc ttacctatcg
    66061 gatattgaaa caggcaaggc agtccctact caacaggtga aagaagattt actgaacgct
    66121 ttggaacgct tcaatcccga taacccattg gagatgttat tcgactatgt acggattcga
    66181 ttccctacca atgatgtggc tcaaattatc ggtgaggttt tacgtttgaa tatggattat
    66241 atgctacacg aagactttgg ctattattct tatcccgaac actatcgttt cggtgatatt
    66301 gttgtcctag tctctcatga tgtaagtaaa ggtgttttat tagaactgaa aggaaaaggc
    66361 tgtcggcaat ttgaaaactt tctattggct caacatcgga gctggtatga tttctttcaa
    66421 gattgcatgg aacataaagg tattttcaaa cgcttggatt tagctatcaa cgataaaaca
    66481 gggattttga atattccaga tttggcaaag aaatgtaaac aggaagaatg catttccgtc
    66541 tttcgaagct ttaaaaatta tcgcagtggt gaattggttc accgtgatga aaaaccatac
    66601 atgggaaaca cactttatat tggctcatta aaaagtgaag tctatttctg tatatatgag
    66661 aaagattatg agcaatacgt gaaaaatgat gttcccttag aagacgcaga agtaaagaat
    66721 cggtttgaaa ttcggttaaa aaatgaccga gccacccaag ccatgaaaga tttattggca
    66781 catcaacagg cggaaaaaac agcctttgaa attatcaatc gctatatccg ctttgcagat
    66841 aaagacgaca ctaaacgtcg gagtgattgg aaaactaatg aacgttggga atggtttatc
    66901 ggtaaaaatc gtggagcatt acgcctaacc acacagccag agccttattc ttttgaacga
    66961 acattgaact ggttacatca tcaagtcgcc cctacattaa aaatcgcaag cattttagat
    67021 gttctcaacg gtacaaccat tatctccacc atgattcagg aagccaaact gacagaaaaa
    67081 catgagaaat taattgaaca acaacatcta gccatggagg atttgattac atgagccttt
    67141 taacaaaaga attaaagaag ttagggtttc agtgtggcat tgagtttcaa gcgtatatac
    67201 aaaatacagg gaaatatacg tctctcatta ttgagggaaa acggcaagct ggtgatacca
    67261 tctataccta tgatttttac aaggtgagat tttataataa ttataccaat cgagtaaccg
    67321 tctatggaga gcatttaacc ccttttcaat tattaaggcg tgtaaaaagc tatatctatt
    67381 atcgagaaaa atatcttaag gaaaggagga caatcacatg aattttgggc agaatttgta
    67441 caactggttc ttggataatg cacagtcatt ggtattgtta gcgattgttg tcattggact
    67501 gtttttaggt tttaaacgag aattttcaaa actcattggc ttcttgatta ttgctctaat
    67561 cgccgtcgga cttgtgttca atgcagctgg cgtgaaagat gtgttattaa acttatttaa
    67621 ccgaatcatt ggtgcttaac agatattttt catgataaaa taggaagtat atattttgtt
    67681 atgaaaggat ttatgaatat gtttacaaat gatcaattta aatctctttt aattaaaaca
    67741 ttagaaagaa agagctcttc aaattattat gaaggaggta acgagattgt ttctaaaatg
    67801 aaaatatcag aggtaacttt agatgagact gacgatttta cttattataa aggatataaa
    67861 aagggctgga atacgctttg cacatatctt aaaataagag ttccttttga tgatttagac
    67921 ttttttgaaa gtcataaaga tttgattacc cagacagcaa gctccatata tgataaacaa
    67981 ggtgataatg tattagtgga tactatttta gtaccacttc cagagaatta cgaagtaatt
    68041 aactttagtc agttgaaaat tagtgatgtg gtttcacaag ctattgaaga cgctgagtct
    68101 tttatgagta atggtgaata tcaacgtgcc tttgacagag ttcacactgc ttttcatgga
    68161 tatttaattg aaatactaaa aaaatatgaa attacagttc ctagagacga aaatctatct
    68221 aaattatat
//
LOCUS       DACDAF010000004        68220 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.004, whole genome shotgun sequence.
ACCESSION   DACDAF010000004 DACDAF010000000
VERSION     DACDAF010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 68220)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68220)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68220
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.004"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            30..911
                     /locus_tag="IVZ69_000205"
     CDS             30..911
                     /locus_tag="IVZ69_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182326.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            924..2534
                     /locus_tag="IVZ69_000206"
     CDS             924..2534
                     /locus_tag="IVZ69_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HAP8182327.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAKGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(2611..3270)
                     /locus_tag="IVZ69_000207"
     CDS             complement(2611..3270)
                     /locus_tag="IVZ69_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP8182328.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(3553..4218)
                     /locus_tag="IVZ69_000208"
     CDS             complement(3553..4218)
                     /locus_tag="IVZ69_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182329.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(4365..4970)
                     /gene="dhaL"
                     /locus_tag="IVZ69_000209"
     CDS             complement(4365..4970)
                     /gene="dhaL"
                     /locus_tag="IVZ69_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HAP8182330.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(4998..5981)
                     /gene="dhaK"
                     /locus_tag="IVZ69_000210"
     CDS             complement(4998..5981)
                     /gene="dhaK"
                     /locus_tag="IVZ69_000210"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HAP8182331.1"
                     /translation="MKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRVVAKNQKAEQ
                     VGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEADSGKGVLLIV
                     KNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAGTVLVHKIVG
                     DAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDEIEYGVGIHG
                     EPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQFVFMNDVLA
                     LLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTISW"
     gene            complement(5983..6378)
                     /gene="dhaM"
                     /locus_tag="IVZ69_000211"
     CDS             complement(5983..6378)
                     /gene="dhaM"
                     /locus_tag="IVZ69_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HAP8182332.1"
                     /translation="MKKSILLISHSQKVTDGIKEMIEQMQKSEEVQIFSLGGINGEIG
                     SDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEEEQQQRYHLVDAPLVEGA
                     FAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            6532..6852
                     /locus_tag="IVZ69_000212"
     CDS             6532..6852
                     /locus_tag="IVZ69_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HAP8182333.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(6964..7833)
                     /locus_tag="IVZ69_000213"
     CDS             complement(6964..7833)
                     /locus_tag="IVZ69_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP8182334.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(7929..9233)
                     /locus_tag="IVZ69_000214"
     CDS             complement(7929..9233)
                     /locus_tag="IVZ69_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP8182335.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(9230..9739)
                     /locus_tag="IVZ69_000215"
     CDS             complement(9230..9739)
                     /locus_tag="IVZ69_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182336.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(9914..12049)
                     /locus_tag="IVZ69_000216"
     CDS             complement(9914..12049)
                     /locus_tag="IVZ69_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP8182337.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(12132..13787)
                     /locus_tag="IVZ69_000217"
     CDS             complement(12132..13787)
                     /locus_tag="IVZ69_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP8182338.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(13789..14103)
                     /locus_tag="IVZ69_000218"
     CDS             complement(13789..14103)
                     /locus_tag="IVZ69_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP8182339.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            14273..14533
                     /locus_tag="IVZ69_000219"
     CDS             14273..14533
                     /locus_tag="IVZ69_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HAP8182340.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            14547..14861
                     /locus_tag="IVZ69_000220"
     CDS             14547..14861
                     /locus_tag="IVZ69_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur reduction protein DsrE"
                     /protein_id="HAP8182341.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(15591..16145)
                     /locus_tag="IVZ69_000221"
     CDS             complement(15591..16145)
                     /locus_tag="IVZ69_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HAP8182342.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(16271..18200)
                     /locus_tag="IVZ69_000222"
                     /pseudo
     CDS             complement(16271..18200)
                     /locus_tag="IVZ69_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(18506..19222)
                     /locus_tag="IVZ69_000223"
     CDS             complement(18506..19222)
                     /locus_tag="IVZ69_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP8182343.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(19223..21046)
                     /gene="glpO"
                     /locus_tag="IVZ69_000224"
     CDS             complement(19223..21046)
                     /gene="glpO"
                     /locus_tag="IVZ69_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HAP8182344.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(21060..22556)
                     /gene="glpK"
                     /locus_tag="IVZ69_000225"
     CDS             complement(21060..22556)
                     /gene="glpK"
                     /locus_tag="IVZ69_000225"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HAP8182345.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(22692..24152)
                     /locus_tag="IVZ69_000226"
     CDS             complement(22692..24152)
                     /locus_tag="IVZ69_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8182346.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(24142..25437)
                     /locus_tag="IVZ69_000227"
     CDS             complement(24142..25437)
                     /locus_tag="IVZ69_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP8182347.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(25769..26446)
                     /locus_tag="IVZ69_000228"
     CDS             complement(25769..26446)
                     /locus_tag="IVZ69_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HAP8182348.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(26476..27567)
                     /locus_tag="IVZ69_000229"
     CDS             complement(26476..27567)
                     /locus_tag="IVZ69_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HAP8182349.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(27668..28102)
                     /locus_tag="IVZ69_000230"
     CDS             complement(27668..28102)
                     /locus_tag="IVZ69_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP8182350.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(28686..30143)
                     /gene="ascB"
                     /locus_tag="IVZ69_000231"
     CDS             complement(28686..30143)
                     /gene="ascB"
                     /locus_tag="IVZ69_000231"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP8182351.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(30140..32035)
                     /locus_tag="IVZ69_000232"
     CDS             complement(30140..32035)
                     /locus_tag="IVZ69_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8182352.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(32093..33868)
                     /locus_tag="IVZ69_000233"
     CDS             complement(32093..33868)
                     /locus_tag="IVZ69_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP8182353.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(33918..35414)
                     /locus_tag="IVZ69_000234"
     CDS             complement(33918..35414)
                     /locus_tag="IVZ69_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP8182354.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(35608..37230)
                     /locus_tag="IVZ69_000235"
     CDS             complement(35608..37230)
                     /locus_tag="IVZ69_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP8182355.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(37558..38871)
                     /locus_tag="IVZ69_000236"
     CDS             complement(37558..38871)
                     /locus_tag="IVZ69_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP8182356.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(39116..39340)
                     /locus_tag="IVZ69_000237"
     CDS             complement(39116..39340)
                     /locus_tag="IVZ69_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182357.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(39360..39728)
                     /locus_tag="IVZ69_000238"
     CDS             complement(39360..39728)
                     /locus_tag="IVZ69_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP8182358.1"
                     /translation="MIQKTRVMLYVNDVEMICRFFVEKIGAEISETIELPEEFKSIVL
                     SISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETIYENMEEPGEITDNNGILT
                     FNFSDPEGNYFVIGKAESSD"
     gene            complement(39924..40634)
                     /locus_tag="IVZ69_000239"
     CDS             complement(39924..40634)
                     /locus_tag="IVZ69_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182359.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(40652..41149)
                     /locus_tag="IVZ69_000240"
     CDS             complement(40652..41149)
                     /locus_tag="IVZ69_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8182360.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(41186..41638)
                     /locus_tag="IVZ69_000241"
     CDS             complement(41186..41638)
                     /locus_tag="IVZ69_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003331879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP8182361.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(41773..42378)
                     /locus_tag="IVZ69_000242"
     CDS             complement(41773..42378)
                     /locus_tag="IVZ69_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP8182362.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(42828..43448)
                     /locus_tag="IVZ69_000243"
     CDS             complement(42828..43448)
                     /locus_tag="IVZ69_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP8182363.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(43450..44319)
                     /locus_tag="IVZ69_000244"
     CDS             complement(43450..44319)
                     /locus_tag="IVZ69_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HAP8182364.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(44342..44749)
                     /locus_tag="IVZ69_000245"
     CDS             complement(44342..44749)
                     /locus_tag="IVZ69_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP8182365.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(44768..46057)
                     /locus_tag="IVZ69_000246"
     CDS             complement(44768..46057)
                     /locus_tag="IVZ69_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8182366.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(46084..46386)
                     /locus_tag="IVZ69_000247"
     CDS             complement(46084..46386)
                     /locus_tag="IVZ69_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8182367.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(46411..48504)
                     /locus_tag="IVZ69_000248"
     CDS             complement(46411..48504)
                     /locus_tag="IVZ69_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP8182368.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(48993..49757)
                     /locus_tag="IVZ69_000249"
     CDS             complement(48993..49757)
                     /locus_tag="IVZ69_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HAP8182369.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(49868..50737)
                     /gene="mdcB"
                     /locus_tag="IVZ69_000250"
     CDS             complement(49868..50737)
                     /gene="mdcB"
                     /locus_tag="IVZ69_000250"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HAP8182370.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(50762..51838)
                     /locus_tag="IVZ69_000251"
     CDS             complement(50762..51838)
                     /locus_tag="IVZ69_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HAP8182371.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(51862..52455)
                     /locus_tag="IVZ69_000252"
     CDS             complement(51862..52455)
                     /locus_tag="IVZ69_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HAP8182372.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(52459..54135)
                     /gene="mdcD"
                     /locus_tag="IVZ69_000253"
     CDS             complement(52459..54135)
                     /gene="mdcD"
                     /locus_tag="IVZ69_000253"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HAP8182373.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(54125..54424)
                     /locus_tag="IVZ69_000254"
     CDS             complement(54125..54424)
                     /locus_tag="IVZ69_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HAP8182374.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(54526..56172)
                     /gene="mdcA"
                     /locus_tag="IVZ69_000255"
     CDS             complement(54526..56172)
                     /gene="mdcA"
                     /locus_tag="IVZ69_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HAP8182375.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(56179..57090)
                     /locus_tag="IVZ69_000256"
     CDS             complement(56179..57090)
                     /locus_tag="IVZ69_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP8182376.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            57210..58067
                     /locus_tag="IVZ69_000257"
     CDS             57210..58067
                     /locus_tag="IVZ69_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP8182377.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(58254..58616)
                     /locus_tag="IVZ69_000258"
     CDS             complement(58254..58616)
                     /locus_tag="IVZ69_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182378.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            complement(58805..58987)
                     /locus_tag="IVZ69_000259"
     CDS             complement(58805..58987)
                     /locus_tag="IVZ69_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182379.1"
                     /translation="MIFFISEYINQTPFYSKNTEKINGGQVSTDFSIIVYFSGAFTDD
                     KNFIMNLKNDTTKIKK"
     gene            58962..60401
                     /locus_tag="IVZ69_000260"
     CDS             58962..60401
                     /locus_tag="IVZ69_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP8182380.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(60408..62960)
                     /locus_tag="IVZ69_000261"
     CDS             complement(60408..62960)
                     /locus_tag="IVZ69_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HAP8182381.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(63074..64405)
                     /locus_tag="IVZ69_000262"
     CDS             complement(63074..64405)
                     /locus_tag="IVZ69_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8182382.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(64371..65849)
                     /locus_tag="IVZ69_000263"
     CDS             complement(64371..65849)
                     /locus_tag="IVZ69_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8182383.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(66154..67989)
                     /gene="tdc"
                     /locus_tag="IVZ69_000264"
     CDS             complement(66154..67989)
                     /gene="tdc"
                     /locus_tag="IVZ69_000264"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HAP8182384.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
BASE COUNT        19403 a        14559 c        11672 g        22586 t
ORIGIN      
        1 atatttttag aaaaaggagt ggggttttta tggcagaaat cgtcaaagtc acacatttga
       61 aaaagagctt tggtcgtttc gaagctttaa aagatgtctc tttcaccgta cattcaggtg
      121 aagtcgttgg atttatcgga ccaaatggtt ctggaaaatc cacgacgatt cggacacttt
      181 tagggattat aaaaaaagac ggcggaacgg caacgatttt tgggcaagat gtatgggaag
      241 atagtttatc tatccatgaa cgtctttctt atgttccagg cgatatctct ttgtggggaa
      301 atttgactgg aggagcgatc atcgatctct tcatgaagct tcatggaaaa gggagtgctc
      361 aaaaaaaaga tgaactgatt caacgtttct ctcttgatcc taagaaaaaa gcaaaaaact
      421 attcaaaagg aaatcgccaa aaagtgggct tgattgctgc tttggctgtt gattcggatc
      481 tctatttatt tgatgagcct acttctggtt tagatccttt gatggaaacg attttccaag
      541 aagaagttga aaaattgaaa gaacagggca aatccatcct actttcttct catattctca
      601 gtgaagtcga gcgactagcg gataaagtcg tgatcatacg cgaaggaaca ctcgatgaag
      661 aaggaacact cgatgaattg cgtcatttga ctcgttcgac catcactata gaaacagaag
      721 cagagaatag tcacttagca caattgaacg gtgtccatga ctttgtgcaa aaaggtcacc
      781 tcgctcaatt tgctgctgat aacgaagctt tcgatgtgat tttagctgaa gcgtccaaat
      841 taggtgtgaa aaaatttgaa tctattccac cgactcttga ggatttattc atgagacatt
      901 atgaaggatg aggaggaagc gaaatgactg ataaattttc acgctggtcc accctttttt
      961 ctcaaaacct tagccgtgac tggaaaaaga tcctgatatg gctagtcggt gtcactgctt
     1021 tttctggtgg ttttgtccct gcgtttgaag aattgacttc cggacaagga ttagctggat
     1081 tatacgaaac cttgcaaaac ccggcaatga ttgcaatggt cggaccaact ccagcttcga
     1141 atgctgctga gtatacttta ggagcgatgt atgcaaatga aatgttgctt ttttgcagtt
     1201 tgtttgctgc tgtgatctct gttttacacg tggtgagcca aacgagaaaa aaagaagaac
     1261 ttggtctgat tgaacttatt cgttcctttc gagtcggacg tcaagcaaac tctttagctg
     1321 tcatcgctga aagtattctg atcaatttgc ttttagcaat atcgatcagc tgtacgatga
     1381 tttttttcca agcggattcg atcactgcaa aaggtgcttg gctttttggg ctatctgtag
     1441 gtagtatggg gattttgggg agtgccgttg cactgtttgc tgcacaactg atgccaagtt
     1501 cagccagttc gaatggtctg tctttagcgt ttttaggtgg actttacctt ctacgagcaa
     1561 taacagatgt agctgattcc tccctttcga tgtggaatcc tttaggctgg tcttatttga
     1621 cctatccatt tacaactaac aactggattc ctttgcttta tttgtttttg ttcagtctaa
     1681 tcttgataat cagttcattt gttttagagg aacatcgaga tttgaacacc ggctatatcc
     1741 ccgaacgtga aggaaaaccg tatgctaaac gttctctttt atccttgcgt ggtttattat
     1801 tctatctaaa taaagggatg acaatcagtt ggcttatcac ttttggtttg atgggggcgg
     1861 catacggctc tatctacggg aatatgcaac agtttttaga aagtaacgac ttaatgaaac
     1921 agatgtttat ccaatctggc gtctcaattg aaaaaaactt tacaagcacg atcatggtag
     1981 tcttgatttg tctagctgct attttaccaa ttgctagcat caatcgttta tttacagaag
     2041 aaacccacgg acgtatgaat cagctgttcg caacaaaaat ttctaggaac caactttatt
     2101 ggaccaatat gttactagct attctatttg ctatattggc aatcctgatt agttctggtg
     2161 cactagggct ttctgctttg gcttcgatga aggatgcgaa agacatggat ctattgatgt
     2221 ttcttaaagc cgggttcaat ttcctgcctg ccgttttagt gtttatcgga attagtggct
     2281 ttctattcgg atggcttcct cgaatcggta aacttgctta tatctactta gcttactcct
     2341 ttgcactcaa ttactttggc ggaattttgg atttaccaga atggttttcc aaaacagctg
     2401 tccctagctg ggttccacgg atgccaaacg attcttttga tctttccgtg ttccttacgt
     2461 tatcatgtat cagccttgca ctgttcgtcc ttggttctat tggttatagg cgaagagact
     2521 tactagaagg ataataaaaa agcatgtaca atttcatgct agcctccaaa tctgggtcaa
     2581 aaatccaaca tttggaggtc atttttttat ttacaagtct tctaactgct ctttatcaat
     2641 gatccagact tctcgattct ttctttttac ataaccattc tcctctaata atttaaattt
     2701 tctagataaa gtttcggggg tcgtaccgat aaatgcagca agttctttca ttttcattgg
     2761 caggaaaaag tgatccttcc ctgtcgcttt agctaagtca agcagataga cagcgactcg
     2821 ttcttctact ttttccatca tcaaaaaagt tgtctgctgc tgtacttttg ttaatttctc
     2881 aacgttgatt gctaaaagtt tcagactaag ggcgggataa tgcagtaaga gttccgagaa
     2941 atctttttgt ctcaatatgc aaatttccgt tttttctagt gcttcgccaa ataaagactc
     3001 atttggaacg cctagcaact ggctctctcc ctcatatccg cccggctcta ttactcgtaa
     3061 aagctgttcc tttccgctag cagataattg atacactttc atactgccgg aggccacgat
     3121 cactaattga ggttctccat tcggcgcaag aatctgttct cctttttcca catagtgatg
     3181 tttgacaagt gcgtgtactt tttcttgatc ttgctgtact aagtgattga acaaaggaac
     3241 aaatgaaaca cataaatgat catgactcat aatctctcct ccttctaaac agctatttct
     3301 aataaagaaa cataacttcc cttattccaa ctgataattt tcttttatca tagcataaac
     3361 gtcaagcgaa ccagatacca gcaaatagag tggatttctt tttgtccctt gctttatttt
     3421 ccttcttttg agaccttaag taattgattc ctatcaattt tttaaatatt tactttttga
     3481 ataatcaaaa acaaaccttc actcgcaagc cgagagtaag gtttgttttt cgcattgctt
     3541 atttcgtgtt gtctattgaa atttttccgc acctagcttt tgatatagtg gtgctagttc
     3601 ttgtaaggtt tcagcggtta tttgctcaac gtgttcgatt tcttgcggat agaagaatag
     3661 tttacccatt tgaaaggttc ggtctctcat cgcttttttc aactcttctt gtttctttgt
     3721 atcggacaaa tagtcagaca aagctaagtg gtcgtcaagt tcatgttctg gttgcggcca
     3781 tatgtaataa tccttgatat cgactgtttt gctccactct ttcagtatcg caagcaactg
     3841 gttatacgct gcaatgctac catatcgttc ttcgctttta taatgttggt acatcaaata
     3901 gatttggtat tgtttttgat tcaacaaaac tgctagacag gcattctcgt cttgacgaga
     3961 ttcgcttcgg tacgcgctcc aaaaatgact gcgtaaattc cagccattcg tccagctttc
     4021 gattttaggt ttgctcatgc cgtacatatc aggcaaaagt gcagctgtct ggagctgaat
     4081 ctctttccat ttttgccagt gttctttata ttctttcttg atttgttcaa tcttatctgt
     4141 tggatggctc tctttgagct gtttgaatgc gtagattggt cgatcaaaca actgataatc
     4201 tgattttcca agttccattg tttcgcctct ttccgttatc ttttgtattc tacctgaatt
     4261 ttgcgatatg gacaaataga ggttgtgaaa aagctgttct gcatcaagtc ataagaacag
     4321 ccaaacaaaa aactgcgatg agcatcaccg cagttttatt gaacttaagg ttgattgatc
     4381 acatctaaaa gcgttgaaaa taaaatggca ctagaagcag ctcctgggtc gatatgtccg
     4441 attgcacgct ctcctagata ggaagctcgt ccttttttag ctaccaagac tttggtgtgt
     4501 tcttttgcct ggtcaatgat ttcttttgtt aaattccctg ccttcaatgc ctctgtgact
     4561 ggcagccaaa catctaacat cgttttatcg tcagcttctg cctttcctcg gctttgaata
     4621 cccgctgttc cctgctcgat cacttcgcct aatttttctt gagaatcaat agaatcgacc
     4681 tcttttgtcg ctttcatcat gttcatgaat gcagatccgt ataacggacc agaagcccca
     4741 ccgactttcg atatcatcgc catagagaat actttgaatg tatcgctgat tgtttcagga
     4801 tgatcggctt gaaaagcttc ttcataagct gaaacccctc ttcccatgtt atttccatgg
     4861 tctccatcgc caatcggggt atctagatca ctgagatatt gtttgttctg attgattgcc
     4921 tctgcaaatt gcgtgagcca ttcttggatt tcttgaacgg ttagtttcat attatcaccc
     4981 ttttatcttg agatttttta ccatgaaatc gtctgtacat tgctttctaa agaatctttc
     5041 cattgtgtct ccgtcaagtc gatcagtgtt agagaaagac cttgcatatc tagtgaggtc
     5101 ataaaattac cgacttttcg gaaaactaca ttgacgcctc tttcttccaa cagagctaaa
     5161 acatcattca tgaacacgaa ctgttccatc aaaggcgtcc cgcccattcc gttgactagt
     5221 acacctgctt cttttggtaa attcgagtaa tcatctaaaa tcttagtaac aagttccttt
     5281 gccagtactt tagaaggctg catcttttct cgacgatagc ctggctcacc gtggatacca
     5341 acaccatact cgatctcatc ttctcctagt tcgaatcctg gtttccctac ttctggtaca
     5401 gttgctgctc gaagcgctag accgatcgtc ttagttgcct gtacgacctt ttctcccagt
     5461 tctttcaact cagctaggga agcaccgttt cttgctgcat cgcccacgat tttgtgtaca
     5521 aggacagtac ctgcaactcc gcgttttcca gcagtatacg tactattttc aacggcgata
     5581 tcatcatcta cgatcacact ttctacttca atatcgtcca tagcagctaa ttcctttgcc
     5641 atatcgaagt tcaatgcatc ccctgtataa ttcttaacga tcagcaaaac tccttttcca
     5701 ctatcggctt ccttaatagc cgtctgaatc tgatctggag ttggagaagt aaacacatca
     5761 ccaagcaccg ctgcacttaa catcccttcc cctacaaacc cggcatggga tggttcatgt
     5821 ccgcttcctc caccagaaac caaaccaact tgttccgctt tctgattctt ggctacaaca
     5881 cgggaagatt ctacacgatg aacaagttct ggatagcttt ttactaatcc ttccagcatt
     5941 tcttcgacaa tattgcttgg atcattcatg atttttttca atttattccc atcctttctt
     6001 tccggcattt tgtgcttctg ttaagatttg ctgagtatca tctgttatac cggcagtgat
     6061 ggctgctgca aaagctcctt ccactaaagg cgcatccacc agatgataac gttgctgctg
     6121 ctcttcttcc aacatgtctt ttgccagttc cgagttcaat accgcgctac cgatatccgc
     6181 aaaaacaaaa taactagctg catcgcttga ttcattgact gcttctacga ttttcatcgg
     6241 gtctgatccg atctcgccat ttattccgcc gagagaaaaa atttgcacct cttcggattt
     6301 ttgcatctgc tcaatcattt ctttaatacc atctgttact ttttgactat gagaaataag
     6361 caaaatactt tttttcacaa gaatcttcct ttcttttaca tagttgctaa cgattggttt
     6421 cgctttcatt aatgaacaat tcaagtatat aataaatttc taattttggg aaaatatgtg
     6481 tagtgcttct tgaagtttgt tatactttaa ttaaaagaga ggagtgatcg aatgattaca
     6541 acaacaacga acagtgtaga gggaaaagcc gtagtagctt ataaagggat cgtttttggt
     6601 gaggtcatta ctgggatcca tgcatttaaa gacttggagg cggggttgcg aaatatcttt
     6661 ggcggccgct caaaaagcta tgaaaacgaa ctaatgggtg caagagaaga agcacttgcc
     6721 gaaatggccg aacgtgcaaa agcattagga gctgatgcga tcattggcgt aaaaatggac
     6781 tatgaagtat taggcagcga caatggcatg ctgatggtca catgtagtgg aacagctgtc
     6841 tccacgagat aagtagggga catctgtttt aataactaaa gagagatggg acatgtagtg
     6901 gcactcaaga attagatttt tcagtctaac ttcgaggtac tctaccttcc catcctctct
     6961 tttttatttc tttttgcgga tgattccgta agctgctgcg actaacacac ccgcccctgc
     7021 taaggaataa ctgacagaag ctgttttttc atttgttttt ggcaaagtct gacttgttga
     7081 tttggatggc tctgtcgttt gctgaactgt ttctgtcgtg cttccagagg tcactgattt
     7141 ttctcctgcc gaatgcaaaa tatcttttat tcgttggaaa ctagctgcta agtcagcttt
     7201 ttttgcttca aaatcattag caactgtttg tgcttcgctg atctttccgt ggattgcttg
     7261 actggccgct gtgatatccg cttgagtttg acttagcttt ccagaagctg tttgagcaac
     7321 ctgatttaat tgctgattga attcttttgc ttgttggatc ttcccgtcaa gatctgtttg
     7381 gacagcttcc gcttttgctt tcgcttcggc aagctttttc tcaagttgtg cacggtcatt
     7441 tcccacttta tttttaagat cagctaaatc ttgatcgatt gctgcttggt cttctttcaa
     7501 tttgtttttt gcagcttcta atgcttcttc gagttctttt cttttatttt ccaagtcttg
     7561 caaatgatcg atttggtcag aagaggtaga actatttatt gatgtatctt ctgaagatga
     7621 aatcgtttct cctgaattat ctgtcggtac attggaagtc atttctgttt ccgaggcacc
     7681 gttttcagca ccagaagagc ttatggttgt tgaaggttct gtttgagcag gttcagaagt
     7741 ttccgcaaaa gctgtctgtc ccaataagaa aatactggaa acagcaattg gccagattaa
     7801 cggcttcatt ctttttttca tcacttttcc catccttact actttttaac taatttctta
     7861 ttataagcaa aaatgtttgg aagaaccata aacacaacag gctgtttgtc taaaaaacgg
     7921 tgcatctttt atttttttgt acgttccggg cttttccatg tcccgcttcc ataacctaaa
     7981 atcgttttga ctgctggaat gaaagtcgtc acgatcgtta tcgcgttcac tatccagaac
     8041 aaaagcatat atagtggtgc gaaaagaagg tatttcaatt ttcttcgtcg atcatctaca
     8101 atcagcgaag ctagcaactg gaaaaatcct gcgaccattt caaagcagat gaacacaaaa
     8161 ctgaatgtaa aagtaatata aatctgttcg tagtttcctt gatatacata atgcccgatt
     8221 aatccagcaa aaagaactac ggaaatacaa aagaatattg accagacaat actcaatgtt
     8281 tgatcaatga agatgatcgt tcttccaata tgtttaaaag gatggagcat cacttttttg
     8341 aaattcgtca gccagacttc tgttccacct tttgcccaac gttttctgtg tcgatatagc
     8401 atcttcaacg tcacaggtac ttccatgaaa aagataatct caggagcaaa aacagataac
     8461 cagtcattta actgatgatc ccaagcaata ctgatgtctt ctgtcgctcg atcttgtctg
     8521 aatccgccca catcgatcaa ggcttctttt cgatacatcg tatttgctcc actgtacgca
     8581 taaagaccac cgaaaacagc tgactgtgtt cgtttaatga tgcccacgat acttgagaat
     8641 tcaaccgttt gagattttgc aatcaatttg gtacgatttt ggacatccat atttgcagtg
     8701 accgcagcaa tatgtcttgc accagggcga atgaaataat tcacatacct aatcagtgca
     8761 tctggctccg gtaccgtgtc tgcatcattg cttaaaatca atttcccttt tgcaaaggca
     8821 agtccgatat taaacgcgtg ggcttttcct ttattttttt cgatccgaac cacacgaaga
     8881 ttagcgtatt ttttcatcag tctagctaat atttctggtg tttggtccgt tgaaccatcg
     8941 tctgtcacta atacctcata gttgtgataa ttcaatttcg tcatcaaata ctcgattgta
     9001 tattcgatca caatttcttc attatgggct ggcaccatga tcgtgatgaa cggttcgaca
     9061 ctcaagggaa catctaccca ttctttttgc ttatgtttgt ataaaaacac ataacaccag
     9121 acaccaataa accatacaaa tccgcctaaa atcggataag aaacgagaaa aaaatacata
     9181 atagacaaac aagtatctaa gaataaatta cctgtatggg tgattgagat catttcagtt
     9241 ccaccccatt ttctttatac aaatctgcaa tgaatgtcgt atctagattt ttctcttcgg
     9301 agacagaata aaaacggacc gtttctctct cttcttttgt tccaaaacgt tccgtataca
     9361 cttcttcaag taattcttgt ctttttttca atttttcatc ttcatattca aaagatttat
     9421 ttactttttt gtatagattt cgattgttcc acctagtcaa tacaaatgag gtaatcagga
     9481 aactgaaaaa aatcaataca aaaaagccga ttaagaaata cagcattttc ttttctgata
     9541 aaaaagcgta caaggaaaaa tccttggctc tttctggtct cgttaatggg aaaaagaccc
     9601 atataaaagg aagaacaacg atcatccatc ctaaaagagc cactaacgtt tgccaaatct
     9661 ttaaccagta attacctttt gaaaaatact tatctttcac caaaattgat gcaacttctt
     9721 ctcttgttac ttttttcata tcctcacctc acgttttttt gttacgacgt aggagtttac
     9781 catacatttc atttcttttc acataaagtg ttcctaaatt tttcctaaga aaaagaacaa
     9841 aacatttctc atcagcaaat gaaaaatatt ttgttctttt tatcagttgt tctttttatt
     9901 ttttatctct taattatgtt gctctttcca atacgacaat gcttttcatt cctctagata
     9961 tcgccgtgta catttgtctg cgtcttcttt gctcatctcc atcgttttca aatggatata
    10021 agattacatg atcaaattcc agtccttttg ctagactcaa aggaatgatt tggcagtttt
    10081 ctaatccata tgaatttttt ttaatcgatt cttgtagcgt ttgggtttcc tcttctgttt
    10141 gggtgataac tgccgctttt tctcctttta gagaaaccaa aatctcagct agtattttca
    10201 acaattcttc agaggatcga aaagagcggt attcgggttc ttttccttgc ggtcggatcg
    10261 atacgatgtc gatcttctct tgatccacag cataggtttt gaaaagctct gtgattgctc
    10321 cgctagaacg gtaactattt ctaagatcat accgatggat cggcagatgg tagtcgtcga
    10381 aacaacgcat aatatcagca aaagtagtgg aagaattaaa gattgcctga ttctcgtcac
    10441 ctactaaagt aaagtgagtt tttggaaata attcgatcaa tagacctaat tgtgccaggg
    10501 tataatcttg tacttcatca atcaatagat agcgaaatgc tggtacattt accttttcaa
    10561 caagtaaatg acgaatagct aatataatga ctgcttcatc aacagtacgt gtgggttgcc
    10621 aagcataagc tgagccatat cgtttttcat aaattctttc aaacaactga tgctcatcca
    10681 cccatgccat ttcttcgatt tgtctggtta tttttcgata ttttttttgt aaaagtttcc
    10741 ttgcataagc tacaatactt tgttccgaat catcagaaat caatttaccg aataattcca
    10801 actgcctatc ttctgtcaac gagagtacct gattctgcac agcaggactt tttgcttgtt
    10861 tcaaaagatg attcttccat tcgctcatca gtgccttttt cgttgcttga agcctatcga
    10921 tcaatttagg atgagcagga actttctcat atattttttc gatcgttttt ttagaaagga
    10981 ctgtttttcc atttttagta agtccacgga taaaattcgg atgatctaaa aacaaaggat
    11041 ctgattgttt tagattatcg ataaactttt tgctacgcaa acgttctgtc tgctccgata
    11101 cattttctcc cgtgatacgt ttgaaataag cctcttcacc ttctatttcc tctgctgaaa
    11161 gctgtgaaac cagctgtatg atggttagat tcagtggatt tctttcacct aatgatggta
    11221 ggacattcga aatatagtcg ataaaccgat gattaggtga tagaatcagc aagtcatcgg
    11281 atgtcatcgt atctcgatat aaatagagca gatacgcaat acgctgcatg atagcagagg
    11341 ttttaccact tcctgctacg ccatttacca agatattttg acttttcaca tcccgaatga
    11401 ttgtgttttg ttccgattgg atcgtagcag tgatagcctt catttcattg gtctcatctt
    11461 ggcctaagac ttctaataat acgtcatctt gaatagctac agacgtatca aaaaacttga
    11521 ccaaacgatc tctttccaaa agaaattgtc gtctttcttt aataaccgta tcgattttat
    11581 tttgacgaac cgtataagaa gatggaccaa tcatgttatt gtaaaaaagt tcggcaattg
    11641 gtgaacgcca atcataaaca agattttcat ctgcatcatc tgtgaaattt gctgtaccga
    11701 tataaaagga ttcttttggc tcattatcca gaaagtctac aacgactttt ccaaagtagg
    11761 gacttttcaa taaacgttcg atctttgcta gctgattttc tgcgtttttc tgtttgatat
    11821 tcatctgatc gatttctcta tttttcattt caatcatcga aaaagtatcc aggttatcta
    11881 agtaactgtc aaaattcaat cgaagctcgc cagccatttc tttcaacgac tggtttcctt
    11941 ctatttttgc cgtatccatc gattcccgca gttcgttttt tttatcaatt agcttttgat
    12001 acacgttctt cagatatgct tcttctaact gtttttgtgt gttgaccata cacattctcc
    12061 tcttttttta aagtggtgga accgattagt ttacctcttt taagagtcga atgcaagctt
    12121 tttaacgagt atcatttgtt aggatatatc agttcttcag gtcggacagt ttgatataaa
    12181 gaaaatgcac catcaaggtt ttttacgtgg tagccagact gcttcaagat tctttccgct
    12241 agatagctac gtaatccgct atgacagctg acgatatatt cttgttggct gtctaattca
    12301 tttaatcggt cccgaagttc attcaaaggg atatgtttgg cttccttgaa tttgcccttt
    12361 tccaattctt ctgctgttcg cacatctaat aaaatttttc cttttgctag ttctgtcggc
    12421 aattcatgcc attgtacggt ttcactaagc ccttctgcaa tgttcattgc tgcatatcct
    12481 agcatgttta ctggatcttt ggctgagcca aatggcggtg catacgtcaa ttctaattcc
    12541 ggtaaatcga agatcgtcaa atgccctttg attgctgttg ctaaaatatc gatccgttta
    12601 tccacacctt ttgccccaac accttgtgca ccataaatct cgccagtctc tggatggaag
    12661 atcaacttca gtaaaatatc tgttgcttct ggataatagc ttgcatgatc ttttcctgat
    12721 acatgaatga cttcaaaaga cagttcgttt tctttggctg ttctttcact taaaccggtg
    12781 gatgcggcag tcattccaaa cgttcgtata attgctgttc caataccgcc ttgatttctt
    12841 cgagaaattc cggaaatcgt gtccgcaact tgtctacctt gacgattggc tggtgaagca
    12901 agagaaataa gtgcatcttt tccagtgatt tgctgtttta caacgatagc atcccccacc
    12961 gcataaatat caggaatatt cgtttgataa cgttcgtcta ctaggatacc cccgcgtatg
    13021 cctaattcga ttccagcggt cactgctagc tggttatcag gacgaacacc aatggataaa
    13081 ataactaaat cagcagggat ggtacgccca tcatccagtc gcaatcgttt cccgtggtct
    13141 tcaaatccag cgacagcatg agaagtaatc acttctactc cttgatgaga caattctttt
    13201 tctataaaag ctgccatttc ttcatccagt gttggaagaa tatgtggtgc ttgttcgatc
    13261 accatgactt ctaaacctct tctttttagg ttttctgcca tttccaatcc gatgaatcct
    13321 gcaccaacga tcacggcacg ctttggctgt ttttctaatg catgcatcac tttatcgata
    13381 tctggtacat ttctaataga aaaaacattg tcggcttctg ttatccctgg aatcgatgga
    13441 acaactggtt ttgcaccagg agataaaacc aatgcatcgt actgttcaat gtgtttttga
    13501 ccctcatgta cgacttctac cgttttgttt tcgggaaaga tggctgtcac ttcatgattt
    13561 ggacgcacat ctaaacaaaa acgagcggat aatgattctg gcgtttggac aagaagattt
    13621 tcccgttcac tgatttctcc cgaaagataa taaggcaagc cgcaatttgc aaaagaaaca
    13681 tacggtcctt tttcaaaaac aacgatttct gcatcttcca ttaatcggcg aagccgtgta
    13741 gcagcagaca ttccacctgc tacacctccg acaataacga ttttcatctt atttccctcc
    13801 tactgttcga tcaaaccatt gattcatgcc accacgtaca ttcactacat cataaccaga
    13861 tttctttaat tctttagctg cttgtttact cctcatccct gattgacaaa tcacatagac
    13921 ggtcttttct ttgtctccat catatctgtt tatactttgt aatggaacat ttttagctcc
    13981 ttttatatgc ccgccccggt attctgcagg tgttctaaca tcaagtaacg ctggattttc
    14041 caaaagcttt tcctttaatt ctgggactgt tatcgatttt attgattgaa atagcaaatt
    14101 cattttctgc acctcattta catttttata aatacctcat ggggtatatt aaacaggagc
    14161 tttattaata tgtcaaccag aatgactctt catttttttc actacttttt atatttgcat
    14221 aaaataccga taaggggtat tatctaatta taaaaataga ggagaatgtg ttatggagat
    14281 tgataataaa aatatcctga accgtttgaa acgtacagag ggacaaattc gtggtatcca
    14341 aaaaatgatc gaagacgaaa aagaatgtat ggatgtcatc actcaattaa gcgctgttcg
    14401 ttctagtatt gatcgcgtaa tgggcatgat cgttgcagat aatctgaaaa attgctttga
    14461 gaaacctgat agtaatccag aagaacaagc ggctaaacta gaacaagcga tcaagatgat
    14521 tattaaaaag taaaggaatg atttcaatga aagtcgtttt ccatattgat gaattagaaa
    14581 aatggtcaga aacagggaaa aacgtaaaaa acctgataaa agcttctcca gaaacgacga
    14641 ttgtcgtatc tgtaaatggc atcgcgatta ccggttatct agactctgcc aatgcagaat
    14701 tcttagattt gcaaggagtc gtttttcacg cttgcgccaa tgctatgcgt gctaatcata
    14761 tttcagaaag ttctttacct gaacaagtaa tcgttgtacc agcaggtgtc cttgatttag
    14821 ttgaactgca atcccaaggt tatgcttata tcaagcctta gtcagtagag gttgcgacag
    14881 aagtgatcag cttcaagaaa tttcggctta tttttcgaag aagctacttc tggaaaaccg
    14941 tgaatcaaag gttgtgaaaa cgctgtcctg catcaagtaa taagaacagc caaacaaaaa
    15001 tagcttctca tatttttcgt ttggttgggc ttattaccgc agatgcaagc ttttgaacac
    15061 cgtttaagga agaggttgtg aaatcagcgg tttgacctaa gtattagaga aaaaaacggg
    15121 aaaatagctc ctcatatttt gccgtttttt gagctaatac cgaaggtcag ctgattgaac
    15181 accgtttaag gaagagattg tgaaaaagtc gcttagtttc gagtattaag aaaaattttg
    15241 tgaaaatgga tttctacatt tttgcataaa tttggcttaa taccgagaaa ctggcttttg
    15301 aataccgttt aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagaaacaa
    15361 acggaaaaat agctgctcat attttgccgt tttttgagct aataccgaag gtcagctgat
    15421 tgaacaccgt ttaccaagag gttgtgagcc taccatttaa ctccgaatca caagaaataa
    15481 tttcaaaaac aacttctcct gtttttggtt cggttggctt attatcgaga agtagctact
    15541 gggagtctat ttatcaaaaa aaggaatgcg acataggtca cacccctttt ttattttctt
    15601 tgaaacatct ttcggtactc gacagcatac aagacaaaag attgtaaaag accgtaagtg
    15661 atgacggcaa aaatgactct cacccacagc gttggtaatt ctgggaaaag cagcaaaagg
    15721 atcatgccaa catagatgac agcagtcgct actttgccat accacttcgc tccacttaat
    15781 ttgatatttt tagatagccc gattaatcca gctacaaaca taaagccttc ttttatcaag
    15841 aatagaccaa acaacagcca aagccacggt cgataccatg ccatagacaa aatcagaaaa
    15901 agttgtgtca atttatctgc aaacggatca agcaccttcc ctaagtctgt tacctgatta
    15961 tatctccgag caatgacccc gtctagataa tcagacaaac ctgagacaac aatgaccgct
    16021 cctgctatat aaaatgactg tctcagcaca aaataaagat aaatcggcag caaaaaaata
    16081 cggaatatcg ataaaagatt cggaatcgtt tgtatttctt tacgccagtc tgtgcttaat
    16141 ttcattttat cgccctacct cctcagcact cttttctttt tattttagct tacacgggga
    16201 ataaaaccaa tgatttcact gtttttattt ttctttacag acactgatat tatgagctaa
    16261 tttgagataa tcacttgctg ttttcatcgt ttactcttct ttcttcctgt cgtttgcgca
    16321 tttcttttac tagtacttta tgagcttttt ttgatcctcg ctctaggtca cgctgccgtt
    16381 tacgtgtttt ataatcgata aacagactgt ctaaatcgta acctgtcggg tacagatctt
    16441 ctgctgaacg caccagacga acacgctgac gaggcacgtg gattattttt ttgtctaaat
    16501 atacatcaat cgtatcttca cctatatctt cataaactaa cgcttctttt tggtattcat
    16561 tgacaaatat ccgatcacct tttgcaaaga gctgacgttc ttttttattc tccttcctat
    16621 ttgtaactgc tgtcttagga agaaattctt ttttctgtgt ccgataggct ttttccgcca
    16681 agtaacgctc tgcttgatgg atcaatttca tcgacatatc cattttatga gcaatccaca
    16741 aagcttggct ttctcctgtt tcttccaacc cgcaactgat atttaggacg aagtgcttcc
    16801 cgatcgaaag ccatagcagc cggcacaaaa tcttcatgat ctccggcgaa tttcttgatt
    16861 tctccataat gggtcgtggc aatgatcaat gccccttgct catacataga ttccatgatt
    16921 gcgatcgcta gtgcagcccc ttcatttggc tctgttccac tgccaatctc atctaaaagt
    16981 accaacgtat tcctttttat ctttttcaaa atagcagcga tgttttgcat atgaccagaa
    17041 aatgtactca acgcattttc taaattttgg tggtcaccga catcgacgaa aatctcatca
    17101 aagacagcaa gctctgtccc ttcttttgcc ggaacttgca taccgaacat cgccatcaaa
    17161 gtcaataaac cgactgtctt caacacgact gttttgcctc cggcatttgc tccggtgata
    17221 atcaagcctc gatagtcttt accgatttca acatccaatg gtaccgcatg ctcaggtaaa
    17281 aatggatgtc tgccttgctt gataatgata tgttccgatt tattgattct aggtgtgctt
    17341 ccattgattt ctcggctaaa ttttgcccga gcaaagatga tatctaacac cgtgatcgtt
    17401 tcgatcaata aatcgatcac ttcttcgttt tctgcgatag caccagtcaa tgccgctagg
    17461 acttgatatt cttcactgat ttcttcagct tttaacaact gatagtgttc attcaattta
    17521 gaaatcacag ttggttcaat aaaaaccgtc gttcttttat ttgattcatc gataatcgtt
    17581 ccatctattt tatttttata gctggctttg ataggaatcg tatagtattc gcctttttga
    17641 acaatcattg cttcttggat catttctttg tttttcggat gacgcaagaa tttcagtaat
    17701 tttgactgga tttctttttc gattagttgt aattgtttgc gtactttacg caaattacgt
    17761 gacgcgtcgt cactgacttt attatttttt attttctggt caatcaactc ttctacattt
    17821 atcaaatcag gaagatgttt gctataagca aacaacaagg gtgtctggta ttgattctta
    17881 tcaaaaaact ttgtgatcat ccgactgctt ctaagaaaat ccgcatattc gatcaaatcg
    17941 gttggctgca gaatcaaccc ttttttgact tgttctgtca gtgcatcgat cctcggcaac
    18001 cccataaatg gaacatgctg actgctttct aagatcaagc gtgcttctct tgtttcttct
    18061 tgacgatcca agacagtttg taggtttgtc gagaccgtca tatcgctgat tcgttttttg
    18121 ctatagtttc caattgctct tgcttggatt tcctttttga tccgatcaaa ttgtaattga
    18181 ctaatcattt cgttgtccat attctctcct tttcttgaag agatacctgt cccaaaataa
    18241 ataagggcct agagataaat aaaaggatag aacacagctt aaaaaagtca tgtcctatcc
    18301 ttattagaat acaaagatat tgttttcctg acaggtaccg tttcataagc acaccaaata
    18361 aactttgttt attggctatt cgacttactg attagatacc agctacactc acaaaacata
    18421 ccccattctt ctaggtctta tttattttcc acttaactat agcaagacac attttggttg
    18481 tcaaacttta gtatgtttta tagatttaca ccattaatga atagacacct accgcgataa
    18541 ttgctccgat cattggacct gcgattggta cccatgaata tgcccaatct gaagttcctt
    18601 tattagctat tggcaatacc gcatgtgcta atcgaggacc aaagtcccga gcagggttga
    18661 ttgcatatcc tgttggccct cctaatgaaa gaccgatggc taagatcaat ccacctacag
    18721 cgaatacgtt cgttccaggt gcaaattcgt tttgtccaaa agctagcaac ccaagaacta
    18781 atacaaatgt accaattaat tctgtgatca catttgctgg ataattccgt atagcaggac
    18841 ctgttgcaaa cgttcctaaa atcgcgcttt catctttcgt tgcattccaa tgtggcaaat
    18901 aagaaagcca aacaagaatg gcccctgcaa aagctcctaa aacttgcgca atgatgaaag
    18961 gaacgacaag attccaacta attgcccctg tcatcgccat agctagagag actgcaggat
    19021 tcaaatgagc tgggcccatg aatccagaaa tatagacagc cattgttaca gcgagtcccc
    19081 aaccaaatgc gatgacaatc cagccagaag cctgtgcttt acttttgttt aaattcacag
    19141 ccgcacacac accatctcca agcaaaacta ggatcagtgt cccaataaac tcccccatga
    19201 tttgagtcat atcactgttc atttatttct ccccctttag ttcccgcaga tctgattctg
    19261 caatcaatgc ttctaaacgt ttagtctgtt gcgccttctc ctcttctgtc cattcaaaat
    19321 atccagcaat tgcatcgatc acaggttgct tgatctcatc aagctgatct cgttcaaaca
    19381 acagatgatt tgtacgacga atgagataat cgcctggggc caaaaccatt tcttcttcta
    19441 aaccataacg taaccgagct gactcagcga gactcaaacc aggataaggt gccatttctt
    19501 ttgctaattc aaagatacgt cgggcattag tcccgtaaaa atcagcgata taagtagcat
    19561 cttcttcctc taaaccggct gctactcctt cttttgctaa ttctgtcact gtttcttcta
    19621 atttagttgg atcgaagttt ccacctgaaa tctgatattt tttagagtcg atttctttcg
    19681 tctctattcc gtattcttct tttaataatt ggcgtatcaa tcgcaaagct ccttctgcca
    19741 tcttacggta atcggtgatt ttcccaccag ataaagtcag caaaccatct ggttctcttt
    19801 ctaaagaact acctctggaa atcgtagaag gtgctttttc atcacggctg ttttccaaat
    19861 ggttcaacac gtcttctact tcagcacgag aaactttgtt ttccttatat tcacttactg
    19921 tatcgacaac tttattgaag ctcttgtctg aaatcgatcc attatctcca ccattgtaat
    19981 cagaaccaga attaccaatc aacagtggac gaagtcctgc ccagcttgct tcgatatcat
    20041 tcaatgtgat atttgcttct ggatagcgat gattgatcac atccaataga taatctacat
    20101 cttcttgtgt gactttcgga tccgtaaaat ctccttggta atccgtatct gtcgtaccaa
    20161 agtaagtctt gttttctctt ggaatagcaa aaaccatccg cccatcttgc tttcctgtat
    20221 cgaagtatgt gggttgcggt acaggcagtt ttttcgcatc tacaactaaa tggatccctt
    20281 tagttggacg cattttagga gagactggac gcgtaaaatt caagtttcgt actttatcta
    20341 cccaaggacc actcgtattg atcactaatt ttgctttgat ttcgatcact tcatctgtca
    20401 gcaggtcacg agctttgacg ccaacgattt gatcgccatc atataaaaag ccaaccgctt
    20461 tcattttact tactagataa gccccatctt cggcagcctt tttgatatta tcaatcacta
    20521 aacgggcatc attgttgcgg aaatctagat agacacccgc gccttttagc ccttcttttt
    20581 tcaaaaacgg ttctctttcc aatacttctt ctggtgtcag cgtataattc tcatatttgg
    20641 ttcctgtcac atttgccagt ttgtcataaa ggtccattgc tactttgacc gagaacatat
    20701 tgaaggttgt tgctccttcg ccctcataga ttggcaaaag cattggatct ggttttggga
    20761 tgtgtggggc aatactttgt acgactgcac gttcaccaac tgtgtcagct actacttcca
    20821 catcaaatgt cttcagataa cgaataccgc catgaacaag tttggtcgag cgagaggaag
    20881 tcccttctgc aaaatcctgc atttcgatca atcctgtttt gattcctgat gctgctgact
    20941 ggactgccac accggcacca gtgattccgc caccgatgat caacagatcc aattcttctt
    21001 gctgcatttt ttgaatgcta tcttgtcttg tcttgtttga aaacatatgg atttcctcct
    21061 tattcaaatg cttgggtagc ttttactgct tttttccaac cgttgtaaag tttttctcgg
    21121 cgctcttcct ccatttgaac ttcaaatagc ttgccagctt cataaaattc gcggatctcg
    21181 tctgtatctt tccaataacc gacagctaat cctgctaaaa atgctgcccc tagcgccgtt
    21241 gtttccaagt tttctgctcg ttggatcggt acattcaaga tatctgtttg gaattgcatc
    21301 agatattcat tgtttgctgc accgccatct actttcaata caggaatctt gattccagtg
    21361 tcatcttgca tcgtatcgat gatatctctc acttgataag caatcgactg taaagtagct
    21421 ttaatgatat cttcttttgt cgtaccacgt gtcaagccaa acatagcccc tcgtgctgcc
    21481 tgatcccaat aaggagcacc tagcccaacg aatgcaggaa caacataaac ctcatcttcg
    21541 cttgtagagc gtttcgctgc gtcttctgaa tcgctagctt tttgcaacat ttgaagtcca
    21601 tctctcagcc attgaatcga agaaccagcc acaaaaatac ttccttctaa agcatagtaa
    21661 acctttccat ttatgccgta accaattgtc gtcaataaat tatttttgga taattgcggt
    21721 ttttcaccgg tattcatgac aataaatgaa cctgtaccat aagtattctt gaccatgcct
    21781 ggttcgaatg ccatttgtcc gaataatgcg gcttgctggt ctcctgccat ccctgaaatt
    21841 ggtgcttcgc ttccataaaa atgataacct tgcgtataac cataaacttc tgagttagaa
    21901 gtgacttttg gtaacatcac tcgaggaata tttagtaaat ctaaaatctc ctgatcccaa
    21961 tctagctgat ggatattgaa caacatcgtc cgactggcat tcgagtaatc agtaacatgt
    22021 gcttgtccat cggtcagttt ccatactaac caagaatcga tcgttccaaa catcaattcg
    22081 cctttttcag ctcgttcttg cgcgccttct acatgatcaa gaatccagcg tatcttcgtt
    22141 gctgagaaat aggcatcgat cactaaccct gttttttcgt ggaaaaattc ttgatagcct
    22201 tcatttttta agttatctgc aattccagct gactgtctgg attgccaaac aactgcatga
    22261 tagattggac gtcctgtatc tttttcccat attactgttg tttcacgctg gttcgttatg
    22321 ccaatcccag caatctgatt tggtttgatc cctgattcga tgaacgctcc ggcaataact
    22381 gactgtacag aattccagat ttcatttgca tcatgttcca cccaactttc ttgcgggaaa
    22441 tattgcgtga actctttttg agaactgccg atgtgtcttc ctttcttgtc aaagataatt
    22501 gctcgtgagc tagttgtacc ttggtcaatc gccatgatat acgttgattc tgtcattgtg
    22561 attccctcca ttatatgcaa acgctttctt taactactct tatcatacta ctgttttaaa
    22621 aaaagaaact gtcaaaattt tattcttttt ttcttttttt gacagttttt tattatgaag
    22681 ctatttttta atcaattctt ttcttttttc agcgtctcta ttcttctttt caatcgaata
    22741 atgtcgtaag gtgacgcaaa ttctgacaga taatattcac actgtttttt gtttctctgg
    22801 caaaatgtga tcaccaaatc atattcttta ccttcttcat aacttccaat ctcaataccg
    22861 ccgattcccc tcagttctct gatcagatat tgttgaaaag caatacgata aatcggcaga
    22921 ctttctaaat cgattccaat cactactggt tttgcaatat aaaaatcgat catcaaaaga
    22981 acattggcat actggatcat caggtaacta agctcactat cttcagctct tttcctcggc
    23041 aattgctgca ccgctgtttc ctgtaatttc gccagtaact gtgttaagga atgcccgagc
    23101 attttctgct gctgttccaa aagccgatca cgctcataga cttcgatctt tccaacaaag
    23161 aaaaaccatt cattgttgat ctgggaaatt tggtagccta ctgccttttc ttctttgatt
    23221 ttcaaacgac gaggacgata atgccataac atcgtttccc gaatgtaagt atctaaaaca
    23281 gcggttggta actttttgct ccgtgtcaaa tcatactgat aaaatatttc ttcgtctact
    23341 atcgaaaaag aaacaaaaaa gctgtaaaac atcattgttt cgtatacatt cagttctgct
    23401 gctgttcgac taagatgcat cacgatgatt ggatcgattg cttgataaag ccggtccgac
    23461 tgatagagta atttcttttc tttcaaagtt gcgtacgtac ttttttcatt caatagtctt
    23521 tttttcgtaa tcccgagcca gcaagcaatc tgtgcttctg ctgatgccgt aaacgttgtt
    23581 tctaatacac ggtccaatcc tagaatgaac ggtctttttt ctggtgtatt ttgcaaaaaa
    23641 agcggtcgct gatcttccgg gatatattgg aatagttcat aataaaaata tcgtatctgt
    23701 agctcttctc cgtataattg accgtttttg atttgtaatc caaattcctc taagagctgg
    23761 ttcaattctt tgatctttcg aaaaacagaa gactcactga tattaaacgc tgtcgctaat
    23821 cgaacgatgg atacttgctg atgttctaat aaatagacga gcatcttaaa cttcaagctt
    23881 tcctgcaata aaaacaatag aattttttcc aaacttacat cttcgtccaa cacaagcagc
    23941 gcctgatact catttcgctg tacttctact tttttttcca tcattcggcc aatcaattca
    24001 atatcttcca aatattgatc aaacgaggct tttgacagtt ggacatgctc tctcaaacca
    24061 ttgatagagg ctgttccccc ttgcagaaca aggtttcgca aaatcaggat ctgtaactgc
    24121 tcttttcttt ctaataatgc ttcaatcttc ataggcagta ttcgccacct ttgaccacac
    24181 catatctggc acacggtatt ctggctggaa aaatagctca tgttcttcta actgttcaaa
    24241 cgtccatcct tcttctactg caattgtcag ttggtcaaga aggtggaaca tctctttttt
    24301 gctttggagc tgtgctccaa gaatcttttt ttcagaatca aatagaaatt tgagtttaac
    24361 tttgctttga tttattgctg taagcttgta gtctacgtat cctgtttcaa ttttttgggg
    24421 ataaaaaatg ctctcttctt ctgtcaaacc tacgcttcct aagaaatagc caaaccactg
    24481 attgccgact ggacgatagg ttccctgatc ctttgtctgt gagccactaa ttgtcttgct
    24541 gacatttcgt gctgtacgga cagcgttatt tactagagaa acatacattt tttcatttgt
    24601 tggacgaaaa gttacttgga tcgcatcgcc aatcgcataa acgtcttttt gagacgtttg
    24661 caagtagtca tctacccaga tcgttccatc atcattcaat gttaattgtt cttcccacat
    24721 ctgattgtcg ggacgagaat gattagccag caaaacaaga tcatagttct cctttctttt
    24781 ttccgtctct acaatagcgg tttcattttc ggtcaaagac acaacttgtt cttctaaaaa
    24841 aagtgaaagc ccttgatttt tcatttcctt tactaacggt tctgtcattt caggatctag
    24901 ataacgaaaa agaattgact ttcggctttc gtaaagatgg atttgttttt ttcttgatgc
    24961 caacccttca gctatttcga ttcctgcttg tcctgcacca ataattgcaa ttttctttgc
    25021 attcatgatc ttttgctgaa gagccgttac gttttgtatc tttttaactg ggtgaataag
    25081 cgttgattct gcagaaatat ttcgaaactt ttgatttgaa ccagtcgcta gaatcaaacg
    25141 atcaaaatcc aatttttttc ctcctgctaa aacgactttt ttttctttca atcctattac
    25201 tgtcttttct gtgtaaacat ggattcgata gcggtcagtc agttcttctt tcgtgatcca
    25261 agaaagttgt ttttcactgg taacctttcc ttttaatatc aaattgaacc cgctgggaat
    25321 ccatcctaac ttcgattgct tttcaatcaa atatatttca cttgttggca tcaattggcg
    25381 aagataaata gccgcatgaa tccctgcaaa cgacccgccg acaattacaa tgttcatctg
    25441 cattcctctt tcttataagg tgttctactg ctaacttctc aatcagaaaa cacagtattc
    25501 ataactcgct ttcaacctta tgatacatag cgatgcagca gaatcaaccc tctccatcat
    25561 accgtgttct aggtctgctt ctcaataatg tactagtgga cctaattgaa gagtatcatt
    25621 tctgaagaga tgtttcaaaa aatgtactct tataaaagaa aaaaactcgc cttttacgta
    25681 cctctgtcca aataggaaac agaaaagaac gaaaagacga gttttagcgt gtgtaatgta
    25741 atagttagaa tagacacatc atttattttt aattctttaa tgcttcaaca actgcttcgc
    25801 ctaattgatg agcagattga ggattttgcc ctgtaagaag ccgcccatca atttgaacca
    25861 cttctgaaaa agctgctcca gactgatagt ttgctccttt ttctttcaaa gcatcttctg
    25921 ctaagaatgg tacttcattc gttgtaccat ttgcttcctc ttcttcatta ctgaacccag
    25981 tcactgtacg tccagctaaa atagattttc cagactcatc tgtaactggc aacaatccta
    26041 caacaccgtg acaaacagct gagaccagcc cttcatttcg atagatttgt gaagcgactt
    26101 tcccaagatc tattgcttct ggaaaatccc acattgttcc gtggccacca gcataataaa
    26161 ccgctgcata atcatttgca tccacatcat caggacgtaa ggtatttccc aaggcccgat
    26221 ttctgaaatc ttcatcttca taataggccc aatcgatttc atccatattc aaaacacttt
    26281 gcggttctaa aggtacatat ccgcctttag gactgacaaa atctgcatcg atcccatttt
    26341 ttactaatac atcataaaaa tgagtcagtt cacttaacca caaacctgta ggacgctcga
    26401 tcttttcgta cttttctaca tttgttaata cgatcaatac tttcattttc ccatcctctt
    26461 tctataaaaa ttgcgttatt gataacgtgc tttcaagaaa ttatataatg ggcttggcaa
    26521 ataaagctct ttatatgctt cttcaaaagg tttcgttaca aattcatcct cacggttttc
    26581 caataatttc tctgcccagt caggatcgac gatcatttgc tgtccaattg ctgcaagttc
    26641 tgcatatttc aatacctgct ctacatcttc gcgattgcgg atcccaccga caccaactaa
    26701 agggatcttt ccttgaatcg tgttatggac cacttcaaga atcgatttat cgttgtattt
    26761 atcagaacga gctattcgat catacatatt taatgaaaca tgcagataat ctagttttga
    26821 ctcacgtaat cgttcaagaa gccagatcgt gtcttcaaaa cggatacctg gtgtttcata
    26881 ttcttctggt gagaaacgat accctacgat gaatggtttt ttagcatatt gttcaaccgc
    26941 tgagaaaacc gttgttaata attcttcaat aaaacgataa cgattttcca agctaccgcc
    27001 ccattgatcc tctcgtctat tcgaatgcgg agagaaaaat tgttggatca aatacgtatt
    27061 tgctccatgc aactcgattc catcaaatcc tgattcaatc gctctacgtg tggctttgcc
    27121 aaatgcttgg attgtttcaa cgatttcttc ttcactcatt gctcgtggtg tttccgcatc
    27181 aggacgtttt gctgcaactg cacttgcaga tacaggctgt tctccagata aagttgctcg
    27241 acttgtcatt cgtccaccgt ggaaaatctg aataatcgct tttgcgcctt ctccttggat
    27301 tgctttcgct agctcactta atcgaggaat catttcatca tgagcgatgc tgagttcacc
    27361 tggccagcct tttccgatat cttggacatt tgcagcacca gtaataacag caccaagacc
    27421 tttagaacgt tgtttataat aagtgatctc atcttcggtg atcactccat tgaaaaagct
    27481 gagttgtgtc gtcataggcg acagcatcaa tcggttcttc aattgaactc ctgaaggtaa
    27541 agtaattgat tgatcaaatt gtgacattgt cattcctccc ataattcgct ctgattaacc
    27601 tatcgagaat catctatcat taaaccactc gattagttgt acatgcaact aatttgctta
    27661 aaaaatttta ttttttttgt aacttatctg ttgcatcatt cattgtctgg gctaattctt
    27721 tacttgcttc atttcccaaa actgctttgt atgactgatg aagttcttcc cagctaccat
    27781 cgacttcctt agcaaattgg cgtccttgtt ctgtaagata aactaatgac aagcgacctt
    27841 cgctaactgt tttgacgtat cctttatatt ctaatttttc aacaaaacga gcaatcgttg
    27901 atggggcgga atagagcatt tgtgcaatat ctttttgtgg tattccatct ttttctttta
    27961 atatcaataa aataaaacca taagttggtg ccagacctgt ccttctaaac gcttcatcag
    28021 ctaatttatt caacatgcga tctagctttt tcacgctaaa gaaaagacat tcatctaacg
    28081 ctttttcaat tggcttttcc atttcatccc ctccattggc gtacatatca tagtatgatt
    28141 tttatttttt gtcaaaaaac acggaataat gtccgcctcc tctgtctaga tttgaaaaaa
    28201 agaagtagcc atcttcaaag aatttcggct tgttttcgac aaaactcctt ctggaacacc
    28261 gtgaatcaga ggttgtgaaa aagtcgttta gttttgagta tgaagaaaaa ttttgtgaaa
    28321 atggctttcc acatttttgc ataaatttgg cttaataccg aaaaactggc ttttgaacac
    28381 cgtttatatc agaggttgtg aaaaagccgt cctgcatcaa gtaataagaa cagccaaaca
    28441 aaaatagttc ctcatatttt gtcgtttttt gagctaatgc cgatggtcag ctgattgtac
    28501 accgtttatt gagaggtcgt gagcctgccg ttgaactccg agtcacaagg agcaatttca
    28561 aaaaacagct tctcatgttt tatgactatg gtgacttgtg atcgaggagt tggcaggaga
    28621 atactgttta ttcgtaaaga aggggctgtg acaagacttt tgtcacagtc ccttatttcc
    28681 ttttattata ggatttcgcc atttgattgg atgacttgtc tgtaccaatc aaatgatttt
    28741 ttctttaacc gtttctttgt gccattccct tcgtcatctt gatcaacata gatatatcca
    28801 taacgttttg acatttgtga agtagaagcg ctgacgatat caatgcagcc ccacgacgta
    28861 taaccaaata aatctactcc atctttgata gcttccttca tctgctcaat atgctgcttc
    28921 aaatagtcaa tgcggtaatc gtcttgaacg gttccatctt cttctacttt gtctatagct
    28981 ccgagtccgt tttcagctat gaacagtggt ttttgatacc tatcatataa ttgattcaaa
    29041 gcaattctca aacccttagg atcaatctgc cagccccatt cacttgatgg aagatacgga
    29101 tttttaattc ctccagttat taagtttcct tggacccctt cccaattttc tggatgagca
    29161 ctgactgcac tagacatgta gtagctaaaa gaaacaaaat caacagggta ggctgctaag
    29221 atttcttcat cacctacttc tatttttaag ttgacacctt tttcttcaaa cattcgttgc
    29281 gtatacgctg gataatatcc tcttgcttga acatcactaa agaacaaaga agttctttgc
    29341 tgctcaattg ttttttgaat atcatccgga tcacaagaat acggaacaag aagctgatag
    29401 ctgatcatac aaccgacttg tgaacctttg ataatttcat gacaagcttt tgtagctaaa
    29461 gcacttgcta taaactgatg gtgtgcacct tggtatttcg cttgttccaa atggggatgg
    29521 ttttcttcaa ttactcctac gctaacaaaa gggtgatgtt ttacacagtt gatctcattg
    29581 aaagtcatcc aatattttac tttattttta tagcgtttga atactgtttc agcgaaacga
    29641 acgtaaaact gaataagctt tcgattaggc catccaccat attctgtaac caaatataac
    29701 ggcatttcat aatgggaaag agaaacgact ggctcaatcc catattttag acattcgtca
    29761 aacacttgat cataaaaaaa taatcccgct tcattgggtg tttcttcatc accatgagga
    29821 aaaattcttg tccatgcgat agacatccga tagcatttaa aacccatttc agcaaataaa
    29881 cggatgtctt ctttaaagtg atgatagaaa tcatttccgt gtcttttagg ataataatac
    29941 ttgctgttgg gatcctgcgc cgcttttact tgctgatgcg tcatcatatg ccattgatct
    30001 gtccattttt ctttaggtaa atcgctgtcg aatgtataca catcagacac agataatcct
    30061 ttttcatcta catcccatgc accttcacat tgattggccg ctgtcgctcc gccccataaa
    30121 aatccttctg gaaatttttt catatcgatc cccctaaact tgctagtttt cttgtttgat
    30181 tatttttctt atgactagta atgatatttt tgaatctact actatttgta acaataacca
    30241 ttgtggtcgg atcatatccc tctttgatta attcttgcaa atctacttcc atcaataaat
    30301 cgcctttacg tacttttttt ccatcagata ctgcactttg aaagtatttg ccatttaaat
    30361 tcactgtatc aataccgata tggatcagta tctctgctcc ttcttcactg actaccccaa
    30421 ttgcatgttt cgttggaaaa actgttgaaa cttccccgtt tacagaactg tagatttttc
    30481 cgtccgttgg aatgatcgca aacccttctc ctaaagatcc actagcaaat gttggatcgt
    30541 ttacttcaga taaatcaatt atttcacctg ctgcaggagt acttaacact atatcctttg
    30601 aggattcttc ttcgatttca tccttgtagc cgaaaagaaa agttagcata caggaactga
    30661 tcatcgctaa gaaataacta gcaactagcc aaacaaatcc ttcaccaata taaatcggga
    30721 aagacaaaat acttcttgta gcaactgcca aagcaccggc tcctgcggca ccagctactc
    30781 caccaaatat agctccacat atacaagcaa tgtaaaatgg tcgtttatat ttaagagtca
    30841 caccataaac agcaggttca gtgattccaa ataatgctgt gataaatgca gataaagata
    30901 aactttttac tttcttattt ttcgttttca aaaatacccc aagtactgct cctgcttgcg
    30961 cagctacggc agtcatacat gctggaccta gcgtatcacg accgtagaaa gaaagattgt
    31021 tggtcattac tggtacaagt ccccaatgta acccaaaaat cactaacact tgccaaaatc
    31081 cgccgataac agcaccagat aaaacagggc taaagttata aacagctaaa tatccagctg
    31141 caatcagctg acttgcataa tctgcaattg gacctacaac taataaaata attgggacca
    31201 tcacgatgat acaaatgaat ggtgtcaata aatttcgaat actttcgtgc aagcttttgc
    31261 gaatcttagg ctcaatataa gaaagaaccc atacagctaa aattgctgga ataaccgtac
    31321 ttgtatacct tgctagaatc acgggcatcc ctagaaatcg caaggttatg ctatcactat
    31381 atgcactgac aatcgtagga taaacgagag ctgctgcaat aaccatagcg atgaaacgat
    31441 ctgtattgaa cttttttgca gcagtatatg ccaaaaatat aggcaagaaa tagaaaaatg
    31501 catcagctgc tgcattcaaa atgatataag ttcctgattc agtagttaat aaattcaaac
    31561 tcgtacataa ggcgagtact cctttgatca aaccacttcc tgccaagacg cctaaagtcg
    31621 gggcaaaaac agcggcgatc atgtctataa aagagtttaa aatgcctttt ttctcagttc
    31681 ctctctttcc actagatgca tcatcttcta gtttcatttg tttggataat acgtcataca
    31741 cttcatttac tgcatttcct actacgactt gaaacattcc tccagcttcg actacagtga
    31801 tcacaccttc tagttgctct accttctcct tatctgcctt cttattatct tttagggtaa
    31861 agcgtaacct tgttgcacaa tggtaaacat tgctgacatt ttcttcgcct ccgacaaatc
    31921 ggacaatatc tttcgctaat tgtgaatagt ccatttttac ttcccccttg ttaattaatg
    31981 ccgtagcaat ccttcttaca agataagtat agttcttaga aaacggtttc tccattcaat
    32041 tagtacccct tctaatagcg aacgaaactg tacaatagtg tgtatggttt acttagccga
    32101 gcaaatcact cactgcttga aagaaaacaa gtatatcgtt tctcttatag tcaaaggaga
    32161 caaaaaaaac acgcttgatc ttcctttgct gatgtataag tggtatctca agctgatact
    32221 ctgtgatttt tgtttctact tggcttttga taagacagca caacaaagtc tcggcattta
    32281 acggaagcat aactaggtca gaactaggag agattagttg ctgaatggaa tctatctttt
    32341 tatggatttt tatttgattt tcttctttgt agtaatgatc aagcagtttt gttttctttt
    32401 tttcttcaac tatggtcagc ttttcacgca aaatctgata aatctcccaa gattcaaact
    32461 catctagaac actaggtaga taaatcaaat catcccactc aaaaataagc tcttgctcag
    32521 tagtcaaaat tgcatcatat tccgttattt tgtttgattg atttttgaaa agatacactg
    32581 gttctatccg gcattctttg atccacatgt tcatactttg ttgaatctgt ttttttagtg
    32641 tattcaaaat actaattggc tggttactaa caatcagtat ctccccttgt tttcgaaaag
    32701 gattcaacgc ttcggcaaga tacaaaacaa aataagcgct ttcagctaaa ttgggacgta
    32761 attgaaaatg tattgggaag aaacgccgaa ttaaataaat ttctaaagga taacgggaga
    32821 tgatcttttg tacaaaatga ttcatggtat tatgtccggc atccatcctc gttttcattt
    32881 gtttgatatg ggttagcaaa aattctgttt catggaacaa taacgaaaca ggaagatcta
    32941 aaaaacgaat aatcgtttgc tcaaatgctc ttagattctt ctctatttct ttgttttttt
    33001 catcattaat catcaaataa tttaactcta atagtcgatt ttcaattgct tgtttttctt
    33061 gattggaaaa agaatagggt agttctgatg ataacttttt tgtgagggtc tctaccatcg
    33121 gaataaataa tgtatacctg tttgtttttt ctaaaagttc ttctcttcga agaatggtca
    33181 aaacgagata ccgagaaaat cgtatgaagt cctctcctga aacaatataa ttatatgata
    33241 taagaacctc ttttaatgtc ttttggacag tcggcatgat attggaaaaa attgtactga
    33301 tttgttgagg aaaccttgcg tgttggatca ccgtttctgt tccaacaaga gataagaaaa
    33361 ttctttttga attttcttca gcaatgattt ttagtccttt tgtcgacgaa acttccagtt
    33421 ctaatttagg attgcgctcg atccaacgca aaatcgtttt tatttgtaat gatacggctg
    33481 tttttgaaag aaagaaaatg tctgctatct tttgcatact gacataccct ttttgaaaca
    33541 ataagtacgt cacaatagtt gaagctcgga aatccatgct ggaatagatt ttatgtttcg
    33601 tcacctcttg tatgatttgc tgtttagttt cagattcaat tgattctaaa aaataacctg
    33661 aacgtttatt tgactggata atgattttct tctcgtagat agcaagcata tttttgattt
    33721 cagtttggat cgttttcttg ttggtaccta aagcttcagc taattcttcg cttgttatcc
    33781 aatgattctt atttcttaat actacaagaa tttggagttg tcgtttattt aagtccattt
    33841 gcttacacct cctctttgtt ataaacatac aggaaaaacc tctcaaatga caatagtcac
    33901 ttgcagaggt ttaaaaatca tttgaagaaa gatctatatt caaggttttt accattagac
    33961 tggataattt gtttataata ttcaaaacta tcttttttca atctcctaaa gcttccgctc
    34021 ccatcatttt gtctatccac ataaataaag ccatatcgct tcctcatttc ccctgttcct
    34081 gccgatacga tatcgattgg tccccaccat aagtaaccaa tgatttggca accatctttt
    34141 attgcctcag caatttcctg aagatgtatt tttagatact cacaacgttt tggatcgtgg
    34201 attcgattca attcatctgg tgcttcatct agtccaatgc cattttcaac tatgaataat
    34261 ggtaattcat aacggtctgt caattcattc atgacataac gaaaccctag aggatcaatt
    34321 ggccaactcc aaggttcggg agatttttcc ttcaaaaagg gattatcgaa accatttgct
    34381 ccgccagtat ctacgcgcat ttctgcttct tttttataga cagcgctacg ataataacta
    34441 aatgcaatat aatctgccgt gttagcttgc aagcactgtt cgtctccatc taacattact
    34501 ggtgcacagt cttcttcctt ccatgtcctg taaatataag ctggataatg ccctcggcac
    34561 atgacatcgg agaaaaacca tgaattgcgt ttaaattgca gtgaaccaaa tacattctct
    34621 ggatcacagt catatgcata agtcgctaat gcagaaaagc tacacataat acccatctta
    34681 gcatttggat cgattttctt taataattga gtagcacggg cgttcgctag aaacatatga
    34741 tgacaggctt gataaatcac tttttttgtt agtgtagcaa tgggttcaag tttatctcta
    34801 gcagggaatg taaccaatcc agcagctgca taaggcatac gaaaagcatt attgatctca
    34861 ttaaaggtca tccaatattt cactttccct tggtagcgtt caaagacggt ctgcgcataa
    34921 aattcaaaaa agtcgattaa ttttcgattt tgccaccccc catactctcc taccaatgct
    34981 aagggggttt cataatgact aagagtaatt actggctcga tatcatatcg atttaatgta
    35041 ttgattagtc tgtcataaaa tacgagacca gcctcatttg gcttctgttc gtctcctctt
    35101 ggaaatattc gtgcccatga gatgcttgtt cgaaaagctt ttaaacctaa ctccttcagt
    35161 aaacgaatat cctcttcaaa tcgatgataa aaatcaatcg cttcatgaga aagataatgg
    35221 agtgattcgt ctaaagcaat ctcccaaatc tttttttctt cattccactg aatactagga
    35281 tgctggttca tgatcccgat aagcgtatct gtcacattag gtaatttgcc gtcttccaac
    35341 catgcacctt cacattgatt agcagctact gctccgcccc ataaaaaatt ttctggaaat
    35401 atttcctgat ccataactat ctctcctcgc tatcaacaat ttcttacttg aagtatagct
    35461 cgattcatca aaacaagata ttctaactat ttcggcagaa gagaagaaaa aaattgaatg
    35521 ctactcttca tttttaatat ttatatataa caaatacata agacgatccc cgaaagaaaa
    35581 cactcgttaa ccatctaagc aaacgattta ttttacttcc aacacaaatg cttcataagg
    35641 tcgtaaatca actttgccgt ctggtaactg tttcagagga taatttgaca caataaccct
    35701 taaagcttca cgtggaatag tgaacgtctg cttttcactg gacatattac aaataacgag
    35761 ccattgctgg tcttcatata tgcgagaata ggcaaagaca tgctcaggcg tcttttccac
    35821 taattcatag tctccccaga cgatgatgtc atgttttcta cgcaaatcga tcaatttctt
    35881 gtacatataa aaaacagaat cttgatctgc taacgcttct tctgcattga tttctttata
    35941 atttggattg actcgaagcc atggaattcc agtagtaaac ccagcatgtt cacgggcgtt
    36001 ccattgcata ggcgtcctag cattgtctct tcctttcgcc ttgattgatt ccaagatttc
    36061 ctcttttgta aatccagaag aaatcctttc gttatacata ttgattgtct caatatcttt
    36121 tgcttccgcg atatcatcga ttgggcaatt cgtcatgcct aactcttctc cttgatagat
    36181 ataaggggtg cctttcatca tatggagcaa gatagcaaac atcttggcac tttcttttcg
    36241 atacacatcg tcatttcccc aacgagaaac aattcgcgga agatcgtgat tattccaaaa
    36301 taaactattc catccttcat cacctaaaga tgtttgccat ttggataata cttttttcag
    36361 ttcagagata ctcaagggtt tcaaatccca tttgtctttg ccttcttgct gatctaatcc
    36421 tatgtgttcg aattggaaga ccatggataa ttcatttctt ttaggattgg aataaagttt
    36481 agcgatttcg gtagttgctc cccatgtttc gccaacagtc atcagatttt tgtcaccaaa
    36541 agttgcttga ttcatttcct gaagatactc atgcagttta ggtccattac ttgtgatttc
    36601 tttatccggt tctttgccaa tcatatcgat cacgtccata cgaaagcccc caataccttt
    36661 atcgatccag aaattcatca tttgataaat ctcttggcga acctgtttat ttttccaatt
    36721 caaatcaggt tgacgcttgc tatacaagtg cagaaaatat tgccccgttt tttcatccaa
    36781 ctgccaagca gaaccactga atattgagcg caatctatta ggctcttttc cattgaccgg
    36841 atcacgccaa atataatagt cccgataagg attttcttta tttttacggg cctcaatgaa
    36901 ccacggatgt tcatcagaag tatgattcac caccagatcc atgatgatac ggatatttct
    36961 tttctttgct tcttcaatca gttcttccat ttcttccatc gtaccgaatt ctgccatgat
    37021 tgcttgataa ttactgatat catacccatt gtcatcattc ggagactcgt atactggaga
    37081 aagccaaatt gcatcaatac ctaaatacgc cagataatcc aacctggaaa taatcccccg
    37141 caaatctcca ataccatctt gatttgaatc ttgaaaactt cttggataga tttgataaac
    37201 aactgaatgg tgccaccatt tttgttccat gattttcctc ctataaatgg atgtttctat
    37261 tttttgctta atcatttatt ttagtctctc tcactaaaaa ttgtaacgct ttcaaatagc
    37321 tattgcacct tgttatcggt aacagaataa aacaaaaaaa cagctgagga aattccctca
    37381 actgtttttt gaaaggattg atttatgcag ggaagaatgc tgatttcaca acttctttat
    37441 aaacggtgtt cactcagctg tcccttggta ttagctcaaa aaacggcaaa atataagaaa
    37501 ctattttttc gtttttttct ctaatactca ggccagaacg ctgatttcac aacctcttta
    37561 tttcacattc aatatccaca tgaatcccac aaatacaaag aacagaccat acatgattgg
    37621 agatacttct tttcctcttt tagctgctaa catggtaatt ggatagaaga taaaacctaa
    37681 tgcaatccca tctgaaatac tataagtcaa aggcatgccg atcaagatca agaatgaagg
    37741 gatcgcaatc tctaagtttc cccattcgat ttgtcgcaaa gattgtgcca tcaatactcc
    37801 taccataatc aatgctggtg cagttacttg tgaagtaaca actgatagta atggagaaaa
    37861 gaacaagcct aacaagaaga aaatccctgt agtaatagct gtgatacctg aacgtcctcc
    37921 aacggcgata ccagctgatg attctacaaa tgcaccaaca ggagaagtac caaataagga
    37981 acccgcaagc atagctgttg aatcagaagc taaagctttc cctacacgag gcatcttgtt
    38041 gtctttcatg aaacctgctt ggtttgctaa tccaactaaa gttcctgctg tatcaaagaa
    38101 agtcacaagc aagaatgtca gcactacgac ccacatttga agagaattga tgtcccctac
    38161 atgttttaat gcaactaaaa atgttggttt caaacttggt gctgcggcaa caatttcaga
    38221 aggcattgga atcaaacctg tgaccagacc taaaatcgtt gtagctgcca tcccgatgaa
    38281 gatgccacct ggtacacgcc gaacaagcaa gatagcagtt acgactaatc caaaaatcgt
    38341 caaccaagta gaaccaacgt tgagtgatcc taatcctact aatgtagatt cattcgaaac
    38401 gatgatccca ccttcgctca gaccaaggaa agcgataaat agaccgatac cgccagaaat
    38461 cgcatatttc aaatctgctg ggatcgcatc aatgatcatt tcccgcagct tgaagattgt
    38521 gatcaaaata aaaatcaaag aagcaacgaa tacgccggct aatgctgttt cccatggaat
    38581 ccccattcct aaacaaacag aataagcaaa aaaagcattg atcccaagag caggtgccgt
    38641 tccaattgga taacgggcta atacccccat taaaacacag ccgatcgcac tggctaatgc
    38701 agtcgcagta aacactgctc cttcatccat tccagaagca cctaatacag ttggatttac
    38761 aaataagata taagccattg agataaatgt tgtaaatcct gccagtacct cacgttttac
    38821 cgtggtgttc aatttttcta tttcgaagta ggaaagtatt ttttccttca tcttccatcc
    38881 ccctaaatcc gaacattata aataaagtcc gttaaaattt cgatttatta ataaaacaac
    38941 gtgttttatc atatactaaa acaaaacata agtaaacaaa aaattcggat tttaagcaaa
    39001 atccgaacgt tccatctgat taaatccctt tatctcaaag ttcatgaaca ttcactttgg
    39061 attacaagaa tttctttatt gtgttaataa agtttcttca ttctagtctc aaaaatcaat
    39121 agtgtgattt gattttacca tttcgtttct gttcttcttt gatgaattct tttgtatcga
    39181 caggattcag attatttagt ccgccaaaac ctgtatcgac catttttccc cagccttttg
    39241 tcttcttttt tcctgatttg agattctttg ctcgaagctt ctcactatgt tttgctcgcc
    39301 gatacttcaa ataaccttct aatcttccca ttagatccac tgtttttcct cctttttatt
    39361 caatcagacg actcagcttt tcctataaca aaataattgc cttcagggtc agaaaaattg
    39421 aaagtcaaga tgccattgtt atctgtgatt tctcctggtt cttccatgtt ctcgtagata
    39481 gtttcaaatt catccgtaaa aaatactaaa gaaggcggtg gtcctaatac ctctggtgaa
    39541 aacttctgca caaatacttt tgggaatacg cctaattcta attcttttga gatgctgagt
    39601 acaatactct taaattcttc tggcaattcg attgtttcag aaatttctgc accaattttt
    39661 tctacaaaga atcggcaaat catctctacg tcattgacat aaagcatcac acgtgttttt
    39721 tgtatcatca tttgaccctt ctttctattt gattttcttt cctgtctata aactgattcc
    39781 attatatcac gaaagcgcaa acaccttgtg tttgatacta ttcaagaaaa ataaagcaat
    39841 agtttctagg attgctttcc tccacaaact ttttttacaa aaaaaaaacg gcaatgaatg
    39901 ccgctcttct tatttcgatt cttttataat tctgcttctg attcatcttt ggttagtgtg
    39961 tgtctaacac tagttacgcc aaatgtttga tcgatttttt ccttcaacgc ttcgattgcc
    40021 tgtgcgccac gtgccgcttg ttcagcattg atggattcaa tgaccagcac cgctgcttgt
    40081 gtttcttccg tcagcatcgt tctttgggct tcacgccagt tgagacagcg acagatcgct
    40141 ccttgttcat catagtagat gatttcttcc ggaagtgccg gagcatcgga atctgcacct
    40201 aaaggcagga atgattcgcc accttgggct tttcctaaat gcagatttcc tgcgatcttt
    40261 tcgatatctt ctccgccgca aggtacgcca aaagacaagg aaatactatt atagatatct
    40321 acaagcggat tgattgggaa aaattcccgt tcttgatttg cacgtttcag taaagcttca
    40381 atagaagaac gtgcaccttt tttagtcttg aatgtggtaa atgcctgacg ccactgagca
    40441 atgacttcgt tttggctgaa tgtttcttct gtaaggtaat ttcttgcttc ttttgctgcc
    40501 tcattcaata attgatgata cgtttcttca ctttcttttg ttacgtggtt atcgatacca
    40561 tttacggata agatttcgat ggttgcttca ggaaatactt cccagaaatt ggtatccact
    40621 attacttttt tcatctgttc acacctcttg attagaataa ttgcttgatg aatagatagt
    40681 ctgtttgggg atcatctccc atataaaaaa catgttcgct gtatttgata aatccttttt
    40741 tacgataaaa agcgagcgca acatcgttgt gttcccaaac accgagccaa atggctgttt
    40801 tttgcttttc ttttgctttt tcaatagctg tatctagtaa aaatgtaccg ataccttgat
    40861 gtttaaattt ttttcgtaca tagattcgct cgatttctaa aaaatgatca gccatttcct
    40921 cagattgact cgttcctgta tttagtttca ggtaacccgc aggctcttga tcgatactca
    40981 ctaggaaaaa atcggtttct ttatctttta gctcttctgt aagtttttct agtgcataag
    41041 cttgtgtcaa gtaatcagct aaatgctccg gtgaattatc ttttccaaat gtatctgtaa
    41101 atgtttcgat actaatttgt tgtagtaagt ctacatctga aggcgtcatt tttcgaattt
    41161 cgtatttatt cacggcttct tcctttcaat agatcctttt attgcctttt ttgacaaaat
    41221 tccaatcttc gctaacattc ttgcatactt tatttaaaag atattccaat tgttttgctt
    41281 cttcgtcaga aagaccattt aatgcgactg cattggagta gttgttttct cgaatgatga
    41341 aaggatagat ttctgctcct tttttagtcg gatagagttt cttgattttt ttattttctt
    41401 tatcttccaa acgttcgatc atcccattgg attctaattt cttgattgct cgggcagtcg
    41461 ttgtacgatc tactttgatc atttctgcta gtttttcttg gatgattcca ggattttcgc
    41521 aaatacgtac taaataaaga tactgtcctc ttgttaaatc gacttctttg aattcgatat
    41581 tgctaataga atctagcgct cgggcaatca ttccgatgtc tcgaaggatt tcagccattt
    41641 catcccacct ttattttgtt tgtaagacta gttcacctct ttttgttgca aatgcaacta
    41701 ttttcaataa aaaaatcaag ttctttttta ataactagta aagtatattc ttttcttctt
    41761 ttacgaaaaa gctcaatcac aatagatctg gtttttgttt tctaaaataa gtaactgttt
    41821 cttcgttgtt cgcttttctg atagctttgg caactcttct atactaaaaa atcccatgtt
    41881 ggaagtttca ttattctcaa taaacttggc ctcttcaccg tggatcgcac aagcaaaaac
    41941 aagtttataa tactgaaaaa gctgtggaat atctttttgt ttattcgtat caaaaactgc
    42001 tcgcaactga gtagtttcta ctgttaatcc tgtttcttca tagacttctt tacgcacatt
    42061 ttcttcagga gacaatccta tttcagcaaa tccaccagga agtgaccatt ctttcgtccg
    42121 tttatcttcg attagtagga ccttgccatc ttttttgata taggcacgaa catctacttt
    42181 tggtgttgga tgtccttctc caatcgttgt gagcgctttt atttcttcga aagtttcttt
    42241 tcctatttca ctgatcagtt ccaatgaaat cgtccggatc tcctcaaaac gctctttatc
    42301 aaatacatct tttccataat atagaccagc ttgagaaagt gcgagtagtc ttttgtattg
    42361 agccaacttc ttgttcattc tcttcccttc ttttttagca aatgtatgac tatgtaatca
    42421 agtatagaag actggtttaa ttacggcaaa taaatataat gaaatctgca ataaataaaa
    42481 gaatgttaaa aaactcgaga acaaaagaca ttcgacttct ctggggctgt gaataaatgg
    42541 cgttcaaaag cttgcatctg cggtaataag ccccaccaaa cgaaaaatat gacgagctat
    42601 tcttgtctgg ctgttcttat taattgaggc aggacagctt tttcacaacc tccccactaa
    42661 acggtgttct cctaccaact cctcggtcac aagtcacaat attcatcaaa catgagaagc
    42721 tgtttttttg aaattgctcc ttgtgactcg gagctgaacg acaggctcac gacctctcgg
    42781 taaacagcgt tcaaaagcca atttttcgat attaagccat ttctttgtta cttattgtca
    42841 ttgatttctt tttctaattt atccaatagt ggagtgtaat ccacttgagt atagtctgtt
    42901 acatcaaatt catatagtgt tcctaactgg aatttgtcat attttcggtc ggcgatgatc
    42961 tttttgaatg cttctttcgt aatatgattg gtccctttcg ttcgatcttc caatacgtca
    43021 ccatagtgat aatgatccat gatatagctc aaatgacgat ctgattcacg atcacgtttg
    43081 taccgacgtt gccataacac ttcaaagtct gctgttaggc gaatcgtgat cacctgatat
    43141 ccgtatctat ctgctaattc ttggagtcgt gctttttgct tatcactaaa aggatactcg
    43201 gacacaatca ctttctttcc tgcttccata tacaaatcaa gtgctttgta atagaaagga
    43261 taaactttcg tcctttcttg ttccgcccgt tcttccaaat tgttaaaccc gatggattct
    43321 gcatagtatt ccttgatttc atcgagcgtg atggcataca tatctggaaa tcgttcccgt
    43381 agtttattca taagatatgt ttttcctgta ccaggactac cagccagaag aatgaaatac
    43441 tttttcatct catttatttc ctaagttaat tggactttcc aagttcataa acagtccaat
    43501 cttatgcttg acaatttctt ttactgcttc atttgctgga atcacattat ggcgaagaga
    43561 cttgttgatt tctgtttcac taaaggtttc tttagctact ttcgtccagt tgactaaaag
    43621 ctccgttcca acattgaatt tgcggatccc gttattgatc aattcaggat aatcttcttc
    43681 tttcacacct gttcctccat ggataactag ggggacatca actactgcat cgatttcttt
    43741 cagcaaggga atgtttactt ctgtttttga tttgaattgt ccatgattcg taccgatagc
    43801 aatagctaat gcatccacgc ctgtagcttc tacaaatttc actgcgtctt ccggtcttgt
    43861 atataccttg tcattttcag cgacatggat tccttcttct gtaccgccga ttgttccaag
    43921 ttctccttct acggaaacac cgtgcgcatg ggcatattct actactgctt ttgtcttcag
    43981 gatattttct ttgaaaggca gatgggaccc atcatacatg acagaagtat atccgctgtc
    44041 gattgcttct ttgatatcat caaagtctcg ggcgtggtct aagtgcaaga ctgcatcaac
    44101 catttcttct tctgcaatag ctgtcattac attgactaac acatgcatgc cgatatattt
    44161 agcggtatcg acacttgttt gaataatgat cggcgaaccc atttcttttg ctgcgcctag
    44221 catagcagga agcatttcta ggttatgcgt attaaaagct ccaactgtaa aattcaactc
    44281 ttctgctgtt tttgttactt ctttcaatgt tgtatacatc ttttattgcc accttatctt
    44341 tttatttgtt tcctttgatc gttacttgtt ttgcaatttg tcgcatctca tccattttgc
    44401 ccatgtagta atcgatccct tgatcatcac cagcacgagc agcatctgca cgcttctggt
    44461 tatagaggct catcagtttt ttatacccat ctccgatcgt ctgtttattt tccaaactct
    44521 tttctaaata ttggatggct tgatcgttca catacaattc agaaaattta agtccaactt
    44581 gttcataaag tttcgctaat ttatgcttat cttgggtagt ggaaatctct tgtttcaatt
    44641 gtgtaatctc tgattgaatc ttttcggtcg cttctggcga tagggctttt tcttcttttg
    44701 ccagaacttt tttcggttct ttttcttttt tcttaaaaaa tccaaacatc attttcccta
    44761 ctttcaatta aaatgctttc aaaactgggc ttaagatcca ggcatataag agtgctgcgg
    44821 ctactgtatc tacatcggtt gctgtagcat tgttgaatcc catcgaatta aagatcgtta
    44881 ctagcaaagc gggcaataat gtaataaaga aaccatgagc aataccgcca atgatcgctc
    44941 ctcggcgtcc gccaactgcg ttgccaaata tccctgctgt ccctccggca aagaaattgg
    45001 ttagcatacc aggtaaaatc atcgctaagc cgaacatggg caaagtaaac atggcaataa
    45061 tcgtaccaat cgttgtcgta atgaaaccta aaatgacagc atttgggcta taaggaaaga
    45121 aaactggaca atctaaggca gggatcgcat caggaactaa tttcatagct atccctcgaa
    45181 atgccggcac gatttcacct aacagtagac gtacaccagc tagcaataca tacacaccca
    45241 ctacgaattg gatggcttgt aaaaaggcaa acatgatata gttttgatct cctgataatt
    45301 cagaagcgaa tggttcgcct gcaaataaaa cagtgatgat atatagcggg accatcacga
    45361 ccatgacaga caaataagta tcttgcagaa attcgaaatg tgtcggcaac ttgatatctt
    45421 cgatcgactt tttattttcg cctttctcac caaaaagctt agcaacaccg gcttcaaata
    45481 agtacccgat cgtacaaaaa tgacctaaag caatatcatt tgatccagtg attttacgaa
    45541 tgatcggttg cgctactgcc ggcatagcaa tggcgaaaca agctccgata aaaccaccga
    45601 ccaagatcaa tacgatccct cgcagaccgg caaaatagcc aaagactgtc gtcatcgttg
    45661 ccatccataa aattgcttga ccagttaaaa aaatgtactt ccattttgtg aaacgagcca
    45721 aaataatatt gaatacaaaa atggctaaga acgtcagtgc aatatctcta cctaaaccca
    45781 aatcattcat tgcttgacca ttgatagatt caatagaagg gatgatccct tgcatatgaa
    45841 atccttcagt aaagattttc ccgaaataag ttaaacttcc aacgatgatg ctcgaaccag
    45901 cactcaacac ttgaaatcct aggagtgtct ttaacgtgcc agagatgact tgtcctgctg
    45961 atttcttctg cagtagtaga cccaacatag caatcaatgc aatggtgatc gatgcctgag
    46021 tcaaaatatt ttcgatgata aaattgataa cgcccatgtt tttaccctct tttctttttg
    46081 tatttagata actcccttat cttgcagaac tggggtgatt ttttcttcaa tttcattttt
    46141 tgaaacaata tttttcaaat agatcatcgc cgttttagga tcaactgcga acttttcgaa
    46201 ctgcgaacga aaattttctg ctgtgatgat cacatctggt ttcatggaaa ctgcggaaga
    46261 aatatcacaa tggtccagtt tggcttctac tcctaatttg ttcaaaacat cctcagcaga
    46321 catctgtgct gcaaaactac ttcctaaacc tgcaccgcat acgaataaaa tgttcaattt
    46381 gttcatcttt gttctccccc gtatcattta ttatttctca actactgaaa aaagcagttg
    46441 tttgaaatct tcgatatttg tgcattcaat caatcgatcc aacttctctt cgttgttgat
    46501 caattcaatt agttctttca tgatgttcag atgcgagtag gagtctactg ctgccaaaca
    46561 aaaaataatc tttactggat ccatttcagg attaccgaaa tcgattggtt gctcaatcgt
    46621 agctacgctg actcctaatt tattgacccc atcttctggt cgggcatggg ctagtgccat
    46681 gtgtttgcca atcacgatat acggtccgta atcattcact gcacgaatca tcgcttcgac
    46741 atagcgctct tcgacaatgt tttctttaac caatggtcta gcagctagtt caatcgattc
    46801 ctcccaagta gtggcttttt ctttgatcat gatattgctg tccgtcaaaa tatcttttaa
    46861 cataggctgg atctcccttt tgttgatttc taaattgttt gtttcgaata atttttctaa
    46921 cttgccatag atgattcgat ctactcggcc accactttct ttcatgacat ctattatttg
    46981 agtgaataac tccgtcgatt catgactgtt aggctctaac cgctgtagtt cttcatttct
    47041 tttcaaaaag tcttctataa ccaagatatt cgtctcagtt aaaatcggat cgacaactaa
    47101 aagcggctta tttcgataat tcaattgaaa ggtgctgaaa accagattga catccaattt
    47161 atctactaat tcgatttctt ttgaacttaa aactgcagta atctcgatct gaggaaactt
    47221 ttctttcaga ttctctgcta acagatttcc agtagccatc ccatggttac agacaacgac
    47281 tgatttataa acataattca agtctcgctt gattacactg gcgatcgtcg aaaagtggat
    47341 gacaagaaaa gctatctcgt cctccagtat cttgccacca attacttctt cgatcgtagg
    47401 aacaaaatga gtgactgcgc ggtagattgg gaaataattt gttcggatgt tttctttcaa
    47461 tggattcatg acttggatat gattcttgat tcttacaatc agtgcagcca tgtgcttata
    47521 gagattttcg aataaagctt cttcctttag atggaaaggt acgtgtgtct cgttctctac
    47581 aaattggatc aattggatcg ttagtaattg agcttgtacc cactcgattg aattggagat
    47641 atctctagca ttgaacgtct caatagtgaa acgaagataa tttctttcta cttgcgggac
    47701 attgtccaat tgaaattcct cgatcatgtg gtcaataaat gcagaaaagc tactgtcttt
    47761 tatttctgta tttttccaat taatggcaga gataaattca tgtttcctga ttcgctggat
    47821 ccagatcaat gtaaaaagca ggatttgttt tttataaata tcatcttctt gtttcaacaa
    47881 cttattggaa tagatctcct gtattttttt gatttccacc aaaggaaaat aatggagaaa
    47941 gattttttga gccggtgtta attgtgcatc ttgattcata aagaagtcgg tcattcccag
    48001 attctgattg ataaaatcat agatcatcgt acggatagat cgttctgaac ctttataaac
    48061 cagtccttgc tttccataac tgacgatctc tatcccataa ctgaccagtg ttgctcgtaa
    48121 ccgtctcata tcttcatcta atgtactttt agagatttga aattcttctt cttttttgtt
    48181 tagatggatc gggattcggc tgtaagcaac ggctaaaact agatcaaaaa tacgttcgcg
    48241 ccgattcaaa aagccgtctt tcacatcttt tatttcagtt tctaatcgag cttgcttttc
    48301 cttttccagc ttcaacaaaa aacctttgtt gcgaattgta cggatctccg gaagcttttt
    48361 actgctcaac cagatattcg cttcaagaac ttcctgacgg atcgtccgct gactgacatt
    48421 gaactcactt gctagatgtt ttgcttttac tggatattgg gctgtcatga ttctgtgaag
    48481 tatttcaatt gttcttgttt tcatagaaat gatctccttc tgatttcaag tatatggttc
    48541 cgcttacata ataaaaagta gatatttctg ccacttgaag tggaaagaaa gtaagcaaag
    48601 caaacaaaaa ataagccata tgctttttca tctcctcaac gaaaaagaca tacgcctatt
    48661 attacaaaaa ttttgcccat ctatacaaaa aagaggttgt gaaaaagctg tcctgcatca
    48721 agtaataaga acaactaaac taaaatagtg cttcctattt ttcgtttggt tgttcttatt
    48781 atcgcagatg caagctttta aacaccattt agtggagagg ttgtgacaga gatgttcagc
    48841 cttgagcgat aagaagcgat tttgaaaaat cgcttcccat attttacaaa atcgtgcctt
    48901 attgccgata ggctatctct ggcacaccgt ttattcagaa aaaggagctg cgacaaggct
    48961 tttgtcacaa ctccgttcat aaatatttcc tgtcaatcca gcataatcgg ctgaataaaa
    49021 tcggcttgcc atcttttttc tttctcagaa aaatcaaaat accatatctg agaaaaatac
    49081 tgtcgttgtg tcttacttcc tgagatcaat cgcccatctt ttcgatcgac tgaataatca
    49141 cagcatctga aatcaattcg gatggcaaaa ctattttcgt ggatctgtcg ataatttcct
    49201 acttcctgaa tagttatttt tttagtatga tttcttacac cgtctgcttt gtttttttgc
    49261 agaactttct gatgttcggc aaacagcttg tctgtataac agcttctggc tttttcagga
    49321 gtttcttctt cccaagcgga ttggatcttc atgaatatct tttggatttc cagaaactgt
    49381 gctttctttt ctttagccgt tcctgacatg cgggacaata tctccgcttt cagccttttc
    49441 ttttgtcttt tattcttgac gatagaaaaa gcagaaaccc ctcctactga caaaacagct
    49501 aatgcaagaa atcccgtttg ctcataacta gaaggacctg tacctggacc ataataccca
    49561 taagaatctc tgccgtaaga acgactgcca aaataactgc ccccatatga acgaccacca
    49621 aatgaacctc tgcccgaact tcgaccgcta gatgtacctc caccatgacc acccgcgaca
    49681 gcgaatcctt gggtcggcag agcaaacaaa cataggccca ctaacaaaat gattgctaaa
    49741 taattgattt ttttcattgt cttcctcgtt atcttttatt acaaaaaact atttttatga
    49801 tagccttgct aaaaggaaga gtcaataacc agatgcataa actgtttttt tagcaatttt
    49861 gtcttattta gtcattgagt aacatcggac aaatgtatgt gtcggcagtc cataattcct
    49921 ctatcttcag catgaacaag cttgcagaca agagatctgc gcttcctcca ggagagattt
    49981 ggttttcctg acaaaagtgc aacagtgctg taaatggacg atttggtaaa gcactttgac
    50041 tagcagcatg agcaagtttt tgcatttcca ctaacgtttt ctgatcactg cgatgcaata
    50101 cgcatgtgtc atctagcgaa ctcatcaaaa ctaacaacat atgcatttgt ttctgtacat
    50161 atgaatcatt atctagctcc ttagctgctt gaattgcaag cctgatatgc ggatacccta
    50221 atatcgcttc ttcatatgca ccatttacgc catatttttg cttcacccta tgaccatgag
    50281 tggttttttt atgacgatat tttgtatcag gaaaagcagc aagcttgctg acatcatcaa
    50341 gtattttcga taaagaaaaa ggctgttcca tactgatttt ttgtgcaatg acactgatca
    50401 atagccccat tgcccaaatc gctcctttat gggtattgat gccatttgta gcaatcagca
    50461 ttgccttttc cgcttttcgc ccaatctcag caattctttc tcttaactcc tgatcaatag
    50521 catgatgcca tgctatttga gccatttctt caaaaaaagg agttagcgtc ttagcagact
    50581 taagaaataa agcatagtcc atatcggaat gtgcacccgc atccagtgca tccactaatc
    50641 caggttttgg acttaatgtt acttctgcga tcaatgcttc ctctaccaac gcagcgagtt
    50701 gctgagtcac tgcttttttt cgttcgtcat ttatcatgac actcactcct tcttcctact
    50761 attacttgct gaaacctttt ttgatagcta cccaaatgat atgaagtaac cagcttaaag
    50821 caaatgcaca acttgccgtc attagataag ctacaagaat catgactcct gaaggtaact
    50881 gcagccaact atctttaaac aataataaca gtacttggaa aacaaataca ttggctaaat
    50941 acgtacgata agcataaaca gacaaccatt tgaacaatgg caattttggc gaatcgttta
    51001 caatcatttt ggaagcgcct atgaagacag caaagatgat gactaaactg tataaacttt
    51061 ggatcgtatt caagtaaggt gcattcgcaa agctcaagtc tcctggatgt gcgagcaatg
    51121 aacggacaga aaagaacgcg ataactaagg caacaggtaa gaaaagataa cgtactctgt
    51181 ccaaatattg atagactttt tcgtgataaa caaatgcggc taccccataa atcatgaaac
    51241 tagcaacaaa ccgatctaat aagtaccagc tgtcatgata aggcccagtc aatacttgtg
    51301 tttgatagaa cagataccat gcgacatata aaatcgttga accaatcaat actggccata
    51361 catatttttt attagcaaat actttgtaac cgagccaaac aaaaaacggc atgaacaatt
    51421 ggatctgcag catcataacg gtataccata aatgaggcgc tccatcacct gtgacatatt
    51481 tcagtaaaaa gcttgcagta tccgtatacg gagtttgttg ttggactgct ggaaatagcc
    51541 aaagataagc cgtcgtccat agaagatacg gaacgactag ttcaaaaaac ttttctttca
    51601 aaaattccca ataagacaaa tgctgacttg tttttaccat attataaaca attgcaaaaa
    51661 taaacattgg tgctgtgtat ttaacgatga cgtaaaaggt accaagaaaa gctgtatttg
    51721 ttgcgctgtg gctgtttgcc aaagcaaagc tcaatatcgt ttgcatcata acagccgtta
    51781 cagctgatac tttctggaag tcacttacgt tgattttgat ttttttgttt tcaaacatct
    51841 ctttctctct ctttttcttt attaccaaag ttctttggtt aatttaggtc cttcgactgt
    51901 tttcaataga atttttttct ctggctctct caaatactct tttagtgaaa aaccgccttg
    51961 ccgagtcact acttgggtat cgaattgctc aaaaaaagca ggatgcgatt gaattacctg
    52021 aattggcaat tcaatcggtg aatttgcgta cagcagcaaa tcaaaatcac tggtttcttt
    52081 tactgccgga atcccagtcg ataattcaaa tcctaagctg ccgccgattc cccatttaca
    52141 tcctgataat atgtttctag cagcatgaaa ttgctgataa acaggataat ccatgatttt
    52201 ctcttgtcta tacgattctt gttcgatgat gtcccacgga tgaatgactt gtttgacggc
    52261 atgttttgag atttctgttg accatctctg attgcgggca ggtccacgta aaccaatcgg
    52321 tagtatttct gcgtgatccg tcgacgcacg acgaactgtt ccgaacatct tttcagttag
    52381 aacgacccat tcaggcaagg tgaacccttc tatttcatgt ttatcaaaaa ggacaatatc
    52441 atgtgcttga atcatttttt atgcatccca ttcttcgtcc attttggcac ggactttatt
    52501 tgtttcgaca cgtccgaatg ttttggctgt ttcgtttgtg tatcgatttg tcagcatcgt
    52561 gtcatttgta ttgcggacat cttgaatggc ttcattgatt gcttcgatga ctttgctgac
    52621 attttgttct gaagcagctt ggtcggtgat atcttctagg aaatgataga tcgctcctag
    52681 ttttgtataa ttattgatat cgtaagcgat agctggaact ttttcagcag ctgcttcgat
    52741 ttcagcaacc gaacgttttg tcacacgtgc agcactttct ttagacatcg cttggacggt
    52801 aatttcttta ttgtttaaag caatcaagcg gcttgattgt aatccatgtg ctaaaaatgc
    52861 acctgaaata gcatttcctg caatcaatcc aataactgga tgtccagctt gacggagttt
    52921 tgcataagca gcagcactat tagccaaagc cacatggata ccgatcaatt cttcgttata
    52981 gccgtatgct tggcttggta catcgatcac aacgatgatt ggccgtttca cttttttgtc
    53041 tttatcttct tcgtaaacgt gatccaaaat ttgtcccatg cggaaacctt caactaaacc
    53101 aacttcaccg tttcgtacac ggtacatcgg gtttttagga tcaggtacga ttgatgtcac
    53161 gatggcttct tctatgaatt tacttgattt accataatac acagtactaa tagaagaagt
    53221 tggatttttc atgccagtta gtgccgcaaa ccaatcgtaa ccaacacttg ctgcagctgg
    53281 ttcatttcct tctgctactt ctggtaagtc aattgatttt gcttgatggt tagcaattgc
    53341 ttcattgtaa tcgtcaatgg ccattggttt tgaaagatct aaagaatcaa gtaatgataa
    53401 ataaaatgct gagctttcac tgcgatgcgt gtcttttcgt tcgtccattg ctgcgatgac
    53461 agcagctttg attgcttcta cactatcagt cactaattca tcaatgattt ttgattctac
    53521 ccgttgacga gatcctaatg tattccaaat caagtctttg tcactagaat caaattctcg
    53581 aacgcctgct tcttgttcaa taacttctgg tccattcaaa ccgactctcg ctttttttgt
    53641 tgcgattaaa taactcatta atgctgaagt aatcgacata ccgccaaatg atcctacacg
    53701 tcctggaatc aaaccgatga ctggtacata ttgttttaga gcaatgatta catttccgat
    53761 ttctgaaata gataacagtc cgtagtttgc ttcttgcaaa cgaacaccac ctgtatctag
    53821 tacaatgact ggaaagatct catttccttt tttattttct tctaacacat gttcaagtgc
    53881 agcaacgatt tttgcaccgg aaacttcacc gataccgcca ccttggaatt ttccttccat
    53941 agcgattact actgcttgtt tgccattgat cgtgccacgg ctgacaacga tcccgtcatc
    54001 actttcaggg acgattcctt gtgctggtaa acttggcgcg atgatttgat cgaatggatc
    54061 aatcaattca cgtccattgt caagtagagc gttcactcgt tctctggcgt ttaattctac
    54121 aaaactattt ttcatctgaa agttcctcca ttgcttgcgt caatcgtagg tacacaactc
    54181 ctggtgtagc accgaagtca ttgatcacga tatctgctga aattggataa cgatcaaaaa
    54241 atctcgttaa tacattgttc catacttcgc cgaagccatc gcttcctgta caaattttta
    54301 cagtagattc tgttttttct gttggaaaca tcaagatttc caaatctcct gaaccgacca
    54361 ctcctacatg gattttctta ttgatcggct gtttcgttgg atatttataa gctaattgtt
    54421 ccatggatct ctcccctttt tgtaaaacag agcatacacg ttctgcttat tcgtctttct
    54481 tcttccatct gggtaaatgg cgacaaaagg tttttctcgc caattttatg accaagttct
    54541 gaatttcatt ggtggttcat acaggccatc tgaccattcg atcaaatcat cgatggtttg
    54601 tgcagctaat aatgaacgtt tcgcttcact acgtttgatg cctagatctt ctggtaattt
    54661 cacgatgccg gctgcacgca agctatctag tgattctttc gtgctagtca ttccaagagg
    54721 tgtaacaccg ccaattgctg caattgctgc ttgtcgttct tcttttgttt ttgctttgta
    54781 caaataagca attccttctt ctgtcacgat atgtgtagta tcttcgctat aaatcatcac
    54841 tggtgcattg gctaagcctg cttgtttttg aacagctagt gcatctaatt cttcgacaaa
    54901 gactggtttt ttatttgaac catatgtttc aaccatttga acaactaatt tttggccttt
    54961 ccctaatgga tcatcattgt cgcgaagtga ttgccatgct ggtgtagaat gacgacgacc
    55021 gccaggatta tgtcccatgt taggcgcacc gccaaaacca gataaacgtc cttttgttac
    55081 ggtagaagag tttccttcgt aatctaattg caaggttgaa ccgataaaca tatcgatggc
    55141 atattgtcct gcagcttgtg ataatgttcg gttactgcgc atcgtgccgt ctttaccgac
    55201 aaaaaagaca tctgggcgag cagcaatata tttttccata ccaacttcgc caccaaaact
    55261 atggatgctt tcaacccaac ctgattcgat ggctggaatc atcgttggat gtgggttcaa
    55321 tacccagttc ttcgcgattt tcccttttaa ccctagtgat tcaccataag ttggcagtaa
    55381 caattcgata gctgctgtat tgaatccaat accgtgattc aaagattgta cgccgtgttc
    55441 tgcgtagatt cctttgattg ccatcattgc cattagaatt tgcaattctg tgatgttttg
    55501 aggatctcgt gtgaataaag cttctaattg ataaggttta tctgctttca cgacaacgtc
    55561 tacccagtca ccagggatat ctacacgtgg taaagaatcg acaacttcgt taacttgaac
    55621 gatcacgata ccatctttga aagctgcagc ttcgatgatt gttggtgttt cttccgtatt
    55681 gaaacctgtg tacaagttgc cgtctttatc tgctttatct gcagctacta aaacaacatt
    55741 tggaatcaaa tcgatgaata agcgtccata aagttccaaa taagtatgga tatcacctaa
    55801 tttcattgtg ccgtcttcaa tcatttgggc gacacgcaag ctttgtgcac cagcataaga
    55861 gaaatcgatc ttgcttgcga ttcctttttc aaaaatattc aaatgttctg gtcgtgagat
    55921 actagacatg atcaaatgca gatcattcac tttttctgca tctacttttt caagactttc
    55981 tgaaagaaaa cttgcttgtt tttgattgtc gccttctaat acaactttgt cgccgggagc
    56041 aatcagtttt tccattactt ctacgatttt ttcagtttct acatacttgc cattgagcaa
    56101 gttgctgatt ttttccaatc gctgcgcttt tttttcgcgt ttagaagccc agttgcggtt
    56161 tggtttttcc ataattagtc atctccattt ttgatataga aacgtggcgt catcaatacc
    56221 atgttggtct agattgatcg tacggatccc tttatctaca ccaaattttg tatgaatcag
    56281 ctttgtcaaa gtattgccgg ggggaaattc aatcgtcaga tccattccta attcttttgc
    56341 caagtccatc atttggttcc actgcacagg gaaagctagg ttttccaaca aatctttacg
    56401 aatctcttct gcgtcctgag tggctcttcc atccgtattt tttatataca aacatctagc
    56461 atcagataga tggacagact gcatatacgg cttgaatttc ttgaccgtat cattcatcaa
    56521 gagacagtga gatggcacag ggactttcag cagcttcgct gtttgcgctt ggtgccgttt
    56581 ggcttctgcc aacgtaacgg ataaaccttc gatactccca gataacgtat gttgcatcgg
    56641 acaattttca tttgacagat aaactggatg gtcaggatca aatgtttttg ctacaatttc
    56701 ctcagcttcg cttctcgtca cacctactac tacgcccatt gcataaccgc ttggataagc
    56761 ttctttcatt aagactgcgc ggtgatagac tagttccgct gcattctcaa atctcaaaga
    56821 tcgacaagca acagctgcac aaaaagcacc aatcgaatgt cctgctgcaa tatcaggctg
    56881 aataccgttt ttttccattt catctaaata aaatactgct tttgtcagta atgctagctg
    56941 gataaaaacc gtatcttgat agttttcttc tttatcaact aaccgatacc ccgtcacatt
    57001 ttctaaacgt tccatgtaca tttcagggat atccgctaac atccctaact tctgactgcc
    57061 ttgtccagga aataagaaac ctgtactcat gagcctcgcc tcctcagcac ttactttttc
    57121 cactgctatc ttagtcaatt tctgctataa taaaaaatgc caaaaaaaga aaaaaccata
    57181 acaaaaaggt atggatggga tggataatta tgaaattgct tcatctgcag tattttaaaa
    57241 aagtattcga aacaaaaaat gttacccaag cagccaaaga attatttatt tctcaacctg
    57301 ccttgagccg tgcgatcaaa catttggaaa acgaattagg tgtccctttg ttttaccata
    57361 gcggcagaaa cattgagacg accgtttatg cagaagaatt ttatccatat gcagtcaaga
    57421 cattagacac attagaagaa ggaatcaaat tattgtcttc ggtcaatgag aagatcgtta
    57481 cttccgtcat attgtattta gaggtagcct ctgtttctat tccgaacttg gtccgaattt
    57541 ttatggaaaa gcatcctgat atccaattaa cgatcatgca acatcattta ccagatgata
    57601 ttaccgatcc tgtactgtac atcacttcgg agatgaagcc tggcatgacc aatattccta
    57661 tcatgaaaga acctgtttat gtcgccattc ctaagaaaca tcctcttgct aaaaaagaac
    57721 atctgcaatt agaagatatc caacgcaccc ccatcttgat gctgtcaaag agcaacgcct
    57781 tccgtcatac actggatgca gcacttgaag cgaaaagtat cgaattgacg atcagttcga
    57841 cgacagatga tcctgcgaca ttacgttcta ttgtcaagca aggattagct gttagctttt
    57901 tcccaaaagt ttcttggtct tacgataaaa atgatccttt cgtcttgcgg gaaatcaaag
    57961 atttgccctt gacacgaaca atttatttat cttctagctt cacagaagat catcctttga
    58021 tcaaaatgat tgcaaaaacg atgcgggaat tttatttagg aaaataaaaa aaaaagagct
    58081 gggacaaaat tcttgtcgca gctctttttt cgaacaaacg gtgttccaga agtaatttct
    58141 tagaaaataa gccgaaattt cccaaaaatt tgagaagcaa ttttcgtaaa ttccttctta
    58201 tttcttgaag ctaaacattt ctgtcacaac ctcttctcta ttgtcctaga cattcattgc
    58261 gttgatttaa aacttccatc aatcaaatct gctagttcat ctagcttttc tattttacgt
    58321 agatcaatag agatccaatg ttctttattc atgtgatagg ctggaaaata cccctctttt
    58381 cctcgcaaaa ttccgccaag ttcaggatcg accttcaaat caagaatatt gatgatccta
    58441 tggtcacttg catcatcata gattttttct tctggaacag acatcaggac cccaaaccat
    58501 tttttgcttt tttgatgtct gaatacgcaa taatcaggaa attttttaaa aatatattct
    58561 ggagacaaat tgtatgtttc attgatgtga tcgattagtt cttttttcgt tagcatctgc
    58621 ttccatctct ttcttattga ttcgctttat tcaaagatac cacgtaagaa tagaaaaatg
    58681 aatacaagta gttgctaatc aaatacttcg atatttttct tttttatcaa ctcttaaatg
    58741 ttcaatccgc ctgtgttggt cttgctacca tctactatta aaatgtttat tattgtttgc
    58801 ccacctattt tttgatttta gtggtatcat ttttcaagtt catgatgaaa ttcttatcat
    58861 cagtaaatgc tccagaaaaa taaacaatga ttgaaaaatc agttgaaact tgaccaccgt
    58921 ttattttctc cgtattctta gaatagaagg gagtctgatt gatgtattca ctaatgaaaa
    58981 aaatcattac cgaaaaagat attcgacgtc atgtttcttt agtagaacaa ttgctgaatc
    59041 atacaaagat aaccgtaaat gaattagctg aaatcatagg gacaaccgaa cgaacgattt
    59101 tttctgacct tcaatctatt cgctctcagc tgcccgaagg ctgggacatc atcagcgatc
    59161 aagcaggaat cagtttgcaa aaccagcaaa atttattaac aaatgacctt tgggagattt
    59221 ttttcaaaca atcagtcagt gtcgaactgc tgaaaaatct gctttttaca aaaaaagttg
    59281 ctgtccctga ttttctagcc gaccatgggc tttcttatgg gacattgaaa agacatgtga
    59341 ctaaaatcaa tcagcgttta gcaagttacg acttgcagat cgatttgacg aaatatacag
    59401 cttgtattct tggaaaagag cgtgcgattc gtacttttta tcatcgattg ctgattcctt
    59461 tcactcataa caactatttt ttcgaggatt attcgatcca tgaatcccat tattttcaat
    59521 ttttaagaaa cctcagtcaa actgaactag cggttgaaac agaagagatt ttcggaacat
    59581 gttggttctt tatcaatacg atccgtataa aagcgaattg ccgattagat tcttctatcc
    59641 ataccaacag cacactctcc tccctgtatg actctgcatt gaaaaaattg tatttaacgg
    59701 aaggtattta tcttaaagac actgagcttt cttttgcttc tttctgcttt ctggaaagtt
    59761 ggaattacaa caataactat ggacaagaaa ccgctcgctg cctgcatcat tctccatttt
    59821 tagaggtcct cgaaacgttt gtagaggaac tagcttcaga gctgtctctt gatcaactaa
    59881 aaaaaacatc tctgactgat aacttggctc tcctcatatt aaaatatcat gaatcgccga
    59941 tattgattga agcattggac cgtcaatacc atcgtttttt agaaacatat gatcagcaat
    60001 atgcacactt gtatcaacag aaagagaatt tactgaacga tctaaaaaaa gaaatagaaa
    60061 tcaatgaacc aaattacttt ctccaactct tgtctctact gatccaacaa acgatttttt
    60121 ctatcaaacc gaatttgttc aatgtctatt ttattttcca aggagaacct tcatggaagg
    60181 cgttcttgca gcaggaatta aaagattact taggaaaacg tgtctgcttc ttacctatcg
    60241 aactaaccga tctttccact atttcttttg aaaaaacaga tatcttgatt tccaatttcc
    60301 ctctagattc tctagatatc cctattgtat acatttcttc tattccaacg aaaaatgagc
    60361 tcaatcgttt gactgaactc actttcaaaa cttttttata gtaacggcta gcgactgtat
    60421 tctctagctg ttttttcttt tttgcgaaac agtttgttca tgatcccttt ttctatttct
    60481 acaactaaga atagaagaat cacatttgct ccaatcaata actgttgtgt catcgttaaa
    60541 cttactgtac cgatcagctg ctggccgact ggtagaaaaa taaccatccc ttgcaataaa
    60601 gcaaggatac ctaatgaaag aaaaagcgct ttgttttgca aaagaccttg gttcaatgac
    60661 ggcttggaca actctctgca attgatcatg taaacagctt gagctaagac gatattttgc
    60721 agaagaatgg tttgctgtaa gctttgccct tcaaactgca tagccaataa ataggcagga
    60781 accatgatca gtagggagac atagatgatc cgaaacaaat gataaccaga taggattcct
    60841 tgctttggat ctcttggtgg gcgcttcatg atttctggat ctggcgactc gaaccctagt
    60901 gcataagata aagtgattgt cgttaccata ttgacccata aaatctgtac tggggacaaa
    60961 ggtagcgggc gattcagcat aagtgcccaa atcaagatca atccttgagc taatgcagtt
    61021 ggcaagaaga aattgatggt tttttgcaaa ttatccaaaa tccgccggcc ctcttttacg
    61081 gcttttgcaa tcgtatggaa attatcatct cctaaaacca tatcagctgc ctgtttgctt
    61141 acttcactac ctttgattcc catagcaatt cctacatcgg atcttttcaa agcaggtgca
    61201 tcatttacgc cgtctccggt cattccgacg atttctccat ttttctgcaa agctttaaca
    61261 attcgcagtt tatgttctgg tgtcgttcga gcaaagacat cgactattgg cacttgctga
    61321 atcaactctt catcagacat aagatccaaa tcgatccctt ctaaaacttt ggcagtatgt
    61381 tttaagccaa tttgttccgc aatcgctttt gctgtgtctt tgtgatcccc tgtaatcatt
    61441 ttcactgaga tccctgcttg ttggcattcc tttacagctt tgactgcact ttcttttggc
    61501 ggatcgatca atccggcgat ccctgcaaaa gttaattggg ttaaagtctc atgcgtgagt
    61561 tcctgtttcg aatctacttt tttataagca aatcctaaaa cacgctgacc ttttctcgca
    61621 aattctgcag ctgtctgact ccatgcttct tgttctgcag aagaaagagt tgatttagca
    61681 aataatactt ctggtgcacc tttgacgtaa atcaccgctc ctttttcctc cgcatgcatc
    61741 gttgccatat atttgtattc agaactgaac ggaatctttg cttctatttt tttcaaaggt
    61801 agattggctg tttctgtgtg tcgaatcagc gcaacttctg tcggattgcc acttaaattt
    61861 tctgttttct gttcttcttt tgtttttaat tcctgacagt ttttcataat ggacaacacg
    61921 caggcttctt cttttgcagc tacatccaca actgtcattt cattttttgt caatgttcct
    61981 gtcttatctg aacagatcac tgtcatagaa cctaatgttt ctaccgaagg aagtcctttg
    62041 atgatcgcct tttcttttgc catttcatgt actccaacgg atagaatcat ggtcaaaaca
    62101 gctggcaatc cttcgggtac cattgacacc accaaagcaa tcgtagccga aagaagaata
    62161 tgccaatcca taccatatcg aaatgtcgta aaaataacta agaataggct caaacaaaga
    62221 atgccttgaa aaatttgttt gtttaatcgg ttgatttttt taatcagagg cgtcgtttgt
    62281 tgttcgaccg attgcaatgc ttgattgatt ttaccgattt ctgtcgtgtt tcctgtttct
    62341 acaacgacac cgactgcaga accagattgt acaagcgttc ctgaaaaacc catatttttc
    62401 tggtcgccga tcgattcttc ttctgtcaaa acggcatgac ttttttcaga tgcttctgat
    62461 tctcccgtca aaatcgattc ttccactaat aaatcatgtg cttcgattaa tcggatatct
    62521 gctggaacga catctccggc acgtaagaca atgacatctc cttttaccag ttctttcgca
    62581 gggatttttt cttgcatccc gtttgatagt actatcgctt cttgtcccat cagctgcttc
    62641 aaaccattca atgattcttc cgcttttctt tcttgccagt aactaacgag tccattgacg
    62701 atcactacga ataaaataat acttccttca atatattcac tagaagcaaa tttcaaaaaa
    62761 gaggcaatga tcaacacgat catcagcaga tcagtaaaat gctttgctat ttttttccat
    62821 cgttttgtct gctgccttgc ttttatttca ttatatcctt gatcagtcag gcgtttctgt
    62881 cgttcttctt gcgacaagcc ttctgttgat gtttgatagt ttttcaatac atcttctacc
    62941 gtcaatctgt accagttcat cctatcccct cctgtttaat tgatactgtt attatacgca
    63001 gggaagtttt ttcaggcgta tcgattattt caggggggtc tgaaataatt cgttttgcaa
    63061 aatgtatctg ggcctaactg atatttctat tgcttattct tttatataca aaatttaaga
    63121 atacaaacca gataaccaat aaaaaaggaa taaagcgtgt cgtgctttcg aataacaagc
    63181 tgaaagcaat tgaagtaaaa aacaccaaca aagcaagatc tttatatctt tgtgtagtgt
    63241 tccgtttctt ttctttaata aattgaacat gtgcacacaa gatcgaagac cacacaaata
    63301 gaaaacaact cgttgtcatg cctgccaaaa gctgaaaaaa caatcgacta tcagctacaa
    63361 aaaaatgtag acaaagaccg gcaaaaaata acattcctgt aattaaaata ccgtgtaaag
    63421 gtacgccttt cttagaaagc gcacaaaacc aatggggcaa acttttttct tttgctgttt
    63481 gatataaaat cctgctagta ctgtagactg cactatttgc tgaggacaaa gaagcaacca
    63541 aaatcattag attgacaatt gctgctccgc cttggcaatg gatcacttgc agcatagtca
    63601 ctaaaggact ttcttttaaa tctaaacaat gccatggaac aacaaataaa atcgacaaaa
    63661 tcgttcctat atagaaaaag agaatacgcc aaggcagaca gttgattgct tttttcaaat
    63721 tcttttgcgg atcacttgtc tcgccaacgg ttaagccgat catttcaatt ccagcaaaac
    63781 tgaataaaac cataggaaat gagactacca ttccagcaaa gccaaacggt agtaattcat
    63841 cgatctgtcc aaaattttct ttgattccga tagactgggt atgaaaatct gagacactca
    63901 atcctatacc caataagata aaaaggaaaa tccccaagat cttgatgatt gagaaaaaag
    63961 attccaattc accaaaccac ttgactgcaa caaggttgac tgccattaag atcattagtg
    64021 cgctacctcc gcttatcaaa gctggtacat gtacaaacca gaaatggata tacaatccta
    64081 ttgctgttaa ttccgcaagt ccagctccaa gccagcaaag ccaataagtc caattgacaa
    64141 aaaatgccca ctttttgcct aaataatagt caacgaaatc actgatagag ttaaatgtac
    64201 tatttgctaa aaataaatca cccatggccc gcatcaaacc ataaatagcc aaaccgcata
    64261 tcaaataaac gagaataaca gctggccctg ctgatgcaat tgcctttgct gaacctaaaa
    64321 ataatcctgt tccaattgcg ccacctaatg cgattaactg gatatttcga ttagttagag
    64381 tccgtttcat tgccggtttt tccatcaagt tcaccttttt ctttttcaag cagcatggcg
    64441 acttcctgtt cccaagaagg tttctttatt ttttcaatac agagtggtac tacaaacaaa
    64501 atgacactga tggctgtgac tgcaattaga ttgatccatg ttccagcttt catcgtcagt
    64561 ccgacagaaa atccgattgc cgcaaataaa acaataacga cagtccaaac tccaagattg
    64621 ctctttttct ctttttttcc aattctaaat ggtcgattca actttgcatg tgtataacgc
    64681 aatctcaaaa ctgcgatccc catgatgaca tagacgatac agtagataac agtagttgaa
    64741 tttacgagca tcaaaaatgc ttgattgacg ccaggaatca gcaaataaaa aagtgcaaag
    64801 attgagataa tgacagactg agtcaaaata acggatttgg atacgtcaaa ttgattcgtc
    64861 ttccaaaaat tgaattttgg tggatacgca ccttttctag cactttctgt cactgtcttt
    64921 gctggtcctg aggcccaagc agataattgg actgctacac caatgaagac aagtaaacta
    64981 aacagattca caataagatg tggcaaacca agaatttggc aataaatcga aatagattgc
    65041 gcgatattat tcaattccat ttgtcctttt ggtacgacat ttgctacaac taaagcattc
    65101 aaaatattga cgaaaaatat aaaaattaac gcggcaaata ctccgcgaat atacgtttta
    65161 actggatttt ccaatcgagt gatatacaca gaggacattt cgataccagt aaaaataaac
    65221 atgatcggcg caaaataaac aaatgaggat gcagtcgtag tatctggtat taatttgtcc
    65281 catgaaaaac tgcctaatgt tccggttggt acgatcccaa ctttgatcca cgcagcaaac
    65341 cctaataaga gcatcatcgt caaaggcacg tacaatccta accaaacacc gacttttccg
    65401 ccgatttttg ccatatcaaa tttcaaattc aaaaaagtga tgatccaata aacgactaaa
    65461 atgacaacta atgtaaattt gctgttcaaa ccaagcggca cattatcgat aatattacca
    65521 aacaacggag cgagtgctga agcgaccatc accatcccag gaaacatttg gacccataac
    65581 agccatgaga caacgaaccc ccattttttt cctagagcat tcgataccca aagttctgga
    65641 ccaccttttt ggggaaacat tccagcaaat tcaccagaga tcaatgagat tggaaaagcg
    65701 tacaataata ctgcaaccag catgtaaaaa atcatcgtcc agctcgttgc tgctacatct
    65761 ggaatatttc gtacacttgc tacaagggcg caggtcattc cgataaaggt catggtcgtg
    65821 atttgctttg atgaaccagt atctttcatc tttattcctt ctttcaatag cgacatatgt
    65881 ttttgttttc ttttattttt gttcaagaac agaaatgaca aggtttcatc gattcagtac
    65941 aaaacccagt atcaccgaaa catccattga acgatcttag tgaactgggt ttgatacatg
    66001 aaacgaacga tccaacttat agaacgtttt ataaaaaaga atatcttggc gaggaatata
    66061 tgaaaaacag ggggaaatac aattgttttg atgaagcaaa taattgtctg ttctccatat
    66121 gtctcttgtt attctttcac acaaaaatca gttctattgg atgatttcgt ttagtttctt
    66181 ttccattgct ttggcgattt tttttgtata aaaattgaaa attcgatcat cattcaaata
    66241 aggagtcatg atagccgcac gtagcagagt gattttctgt tcttttttcc attcttcttt
    66301 cgttagaccc attctttcaa caaaacgaat cggagaatca ccgtaatctt cttgtgtaaa
    66361 tgtagtatga gaagtaataa accgttcacc ataaacatcg ccatccatat aagaagaccg
    66421 atcgaacatt ttttcattta attcattgat agcgttcaaa tctgtacagc cttgttcttt
    66481 gaatacccaa ttgaccatat taaaatcagg atgattcaat ggatagactt cgattgtttt
    66541 tcctttaaca gtaaaagtca gatgatcgag aaattctctg aatctttgag ctgcctcgat
    66601 tgaagcccca atcaattgac catatccggt cacattcaat ggcaatacac gatgtgctgt
    66661 ccagactgcg gcggcggttg ctccagcttt tgatccttcc aaaatataag ctcctaacat
    66721 atctggagcc tttactgatt tttcaaacac atatggcgcg aaataagaaa tgatatttct
    66781 catattttta tgtttgatta cgattcctcc agcagcataa gggacatagc ccatcttatg
    66841 aggatctatc gtgacagaat ccgcttctga aatagctctg aacccttcat atacctcttt
    66901 gtcaatcgtt acgcagtggt ggaaaacatg atgttcttca aagaattcag ctaaggaagc
    66961 atacggcaca aattctcctg cttcgtttag aaacagtgaa cgcgcatagc cgccatatgc
    67021 ggcatcaaca tgtaaataga aatagatccc ttcatctttt aacctttctc ttaattggac
    67081 gattttatct acactgtcta cttgaccttc ttctgtcgtt cctacgacag caaccacacc
    67141 tagaattggg attttttgtc cagctaattc acgaattgtt ttttccaaag cattaatatc
    67201 cattcgataa tcctcttgaa ctgggatagc aaccatctga tctaagccga ctccgcaaat
    67261 atctaacgcc ttcatccaag aatagtgttt tgtttgaggg accagccatt tccctaatct
    67321 ttggatattt tttccgctac gggaagaagc tgctttgacc tcatccattt cttcgtccgt
    67381 aaagctttcg gtcatttcca aaatttcttc aacagataaa ttcaaaagtt cccactcaga
    67441 catttttttc actttttcag gcagcacttc cttgacagct aaaggaatcg atttgatgca
    67501 acgggcgtac cataatcctt caagattagc aatagaacca tctgctgcaa tgtgtcccca
    67561 tccgtctgtc atattgaata atgaagcaaa atcctgtcct acttctgctt ccatttgcga
    67621 agttgccata gaagattcca atgcaacatt atttgggttc cacagcatcg catagttgta
    67681 agctaataaa gcaggcatca atgtttcagc attcatttgt ccccagtaac ggcctgctga
    67741 atgccatggg atcgatcctg cgcgtaatcg ctgactgact tcatccaaga cctctatcat
    67801 atggtcgcgg gtggctagat aatctggagt gagcttatct ccttcgctaa ttgcaggcat
    67861 atctgaagga atataatttt ctctccatcc aagatgttca tctaccatct tgttcaacaa
    67921 cattttataa actggtccat tttcagcttt gtcgcctata aagacggcct tgatatccat
    67981 atctttcatt tttcttccct ccatattttg ttggtcaatg tcttgcagat acatgtgttt
    68041 atctgtaaca cctcttcact atagcgccaa aaatgagaat ttttttttta taacatcaaa
    68101 tccacgtaga tttttacaaa caaaaataaa taaagtcgga tttttctgat aattcaacgc
    68161 aaaaaagcga acaatttttc aataaatcag tcttctaaaa tagataacct aaaaaaagcg
//
LOCUS       DACDAF010000005        65655 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.005, whole genome shotgun sequence.
ACCESSION   DACDAF010000005 DACDAF010000000
VERSION     DACDAF010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 65655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 65655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..65655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.005"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            331..1260
                     /locus_tag="IVZ69_000265"
     CDS             331..1260
                     /locus_tag="IVZ69_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182385.1"
                     /translation="MRSDSRFFVSNLQDDELIRQIDSLLETITESDKRIFLNYVELTR
                     HIIELDKLFNVFRYNLTNLLKHFTIFTNDLIESTGEKLTEDQYYYQINALTINLISSA
                     KTLTESIEVCMKNFLAEKDFKSFKNKILSKPYDEHFSYRFLLHMRNYSQHGHLPVNIH
                     QQRVYFDLDEILAMPHFDFNGQLKKELDVLRKDIYNQFRDSPRISYVYTVAKFNLVIT
                     EIYFNYLKEIKPILIKLNDEKNELLLNTKFQLINSDGSSSDMLFYEFDGENYHCFNRK
                     DNSISMYADIKREVKKILKVEEQYYKEIEKRNQ"
     gene            1429..2754
                     /locus_tag="IVZ69_000266"
     CDS             1429..2754
                     /locus_tag="IVZ69_000266"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182386.1"
                     /translation="MENIEETFLKVLSPYISDSILRFQEQEKNYKFGFDIKNYNDSLH
                     VVFQYNKTGKIGIKEVHIFQIFLAKVNIEASKSKLNYTTLLDTNALFFSKKLLPYLHS
                     YEWALRKLIYLLAPAYFSDNWAEESIPNEIISSIKRKQIQAIGKFDSKNLLQWIDLYD
                     FEEYLFGENYILVTQENEENIVRYKEISQDQLLKLFQDNSHTISDSYSLWSEVFSKYM
                     DVKLEEIQTDMSLIREGRNIVSHNKEIEMALYQKLIKKLKRYTNQLEKAFQKILAGDI
                     AGEDLSDMSDDFEGYIGNYFSNIDLAGVTKLSESLSAMKVLNTDSMKKSMESIGQTLS
                     VQQEIMQNFDTEGIRRATEGINQSLQSIKILNTDSMKRSIESIGQTLSALSAQRAIMQ
                     NFDTKGIRSATEGINQSLQSMKIVNTDSMKRSMESIGKISSTNQVLKSE"
     gene            2854..3672
                     /locus_tag="IVZ69_000267"
     CDS             2854..3672
                     /locus_tag="IVZ69_000267"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182387.1"
                     /translation="MVQGLFGGGTSYEGQSISDIKEDVNNWKIYTENVKSQIVEKKEA
                     LIKNGFWNKIPWNFQQTINESIFCLGTFLSDFQIVESAFEENFISEREIKLLRKIGKN
                     SVQFNHSYGKYFKEEYEWREYGNPEFEIVESIYQHGRDFFVTLQDASNAAGRLEDYMS
                     NNSIYNKVNIFGNSYNTNIQQGHNNNMIVSIDDMSELLSKLDLLLENLNDSLPEEEVE
                     EAQEYIETIKDEAIKEKPKKTMLRFAVDSLKKLKWSTEFLASVATIAQLVAPLL"
     gene            complement(4111..5256)
                     /locus_tag="IVZ69_000268"
     CDS             complement(4111..5256)
                     /locus_tag="IVZ69_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8182388.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(5317..5964)
                     /locus_tag="IVZ69_000269"
     CDS             complement(5317..5964)
                     /locus_tag="IVZ69_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8182389.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            6158..6451
                     /locus_tag="IVZ69_000270"
     CDS             6158..6451
                     /locus_tag="IVZ69_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182390.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            6495..6806
                     /locus_tag="IVZ69_000271"
     CDS             6495..6806
                     /locus_tag="IVZ69_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182391.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            6803..7427
                     /locus_tag="IVZ69_000272"
                     /pseudo
     CDS             6803..7427
                     /locus_tag="IVZ69_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            7727..8089
                     /locus_tag="IVZ69_000273"
     CDS             7727..8089
                     /locus_tag="IVZ69_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182392.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            8126..8974
                     /locus_tag="IVZ69_000274"
     CDS             8126..8974
                     /locus_tag="IVZ69_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein"
                     /protein_id="HAP8182393.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            8964..10439
                     /locus_tag="IVZ69_000275"
     CDS             8964..10439
                     /locus_tag="IVZ69_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HAP8182394.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            10705..11112
                     /locus_tag="IVZ69_000276"
     CDS             10705..11112
                     /locus_tag="IVZ69_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HAP8182395.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            11115..11330
                     /locus_tag="IVZ69_000277"
     CDS             11115..11330
                     /locus_tag="IVZ69_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182396.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            11334..11714
                     /locus_tag="IVZ69_000278"
     CDS             11334..11714
                     /locus_tag="IVZ69_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP8182397.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            11848..12003
                     /locus_tag="IVZ69_000279"
     CDS             11848..12003
                     /locus_tag="IVZ69_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HAP8182398.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            12072..12545
                     /locus_tag="IVZ69_000280"
     CDS             12072..12545
                     /locus_tag="IVZ69_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HAP8182399.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            12542..14236
                     /locus_tag="IVZ69_000281"
     CDS             12542..14236
                     /locus_tag="IVZ69_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAP8182400.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            14202..14387
                     /locus_tag="IVZ69_000282"
     CDS             14202..14387
                     /locus_tag="IVZ69_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182401.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            14391..15566
                     /locus_tag="IVZ69_000283"
     CDS             14391..15566
                     /locus_tag="IVZ69_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP8182402.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            15559..17082
                     /locus_tag="IVZ69_000284"
     CDS             15559..17082
                     /locus_tag="IVZ69_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP8182403.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            17138..17422
                     /locus_tag="IVZ69_000285"
     CDS             17138..17422
                     /locus_tag="IVZ69_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HAP8182404.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            17409..17744
                     /locus_tag="IVZ69_000286"
     CDS             17409..17744
                     /locus_tag="IVZ69_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAP8182405.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            18039..18665
                     /locus_tag="IVZ69_000287"
     CDS             18039..18665
                     /locus_tag="IVZ69_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182406.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            19407..20243
                     /locus_tag="IVZ69_000288"
     CDS             19407..20243
                     /locus_tag="IVZ69_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HAP8182407.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            20308..20742
                     /locus_tag="IVZ69_000289"
     CDS             20308..20742
                     /locus_tag="IVZ69_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8182408.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(20810..22132)
                     /locus_tag="IVZ69_000290"
     CDS             complement(20810..22132)
                     /locus_tag="IVZ69_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HAP8182409.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(22286..23926)
                     /locus_tag="IVZ69_000291"
     CDS             complement(22286..23926)
                     /locus_tag="IVZ69_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HAP8182410.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            24256..24726
                     /locus_tag="IVZ69_000292"
     CDS             24256..24726
                     /locus_tag="IVZ69_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HAP8182411.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            25355..26458
                     /locus_tag="IVZ69_000293"
     CDS             25355..26458
                     /locus_tag="IVZ69_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP8182412.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            26742..27422
                     /locus_tag="IVZ69_000294"
     CDS             26742..27422
                     /locus_tag="IVZ69_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP8182413.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            27512..28546
                     /locus_tag="IVZ69_000295"
     CDS             27512..28546
                     /locus_tag="IVZ69_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP8182414.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            28560..28895
                     /locus_tag="IVZ69_000296"
     CDS             28560..28895
                     /locus_tag="IVZ69_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182415.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            28879..31359
                     /locus_tag="IVZ69_000297"
     CDS             28879..31359
                     /locus_tag="IVZ69_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182416.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWELTAGPTS"
     gene            31415..32974
                     /locus_tag="IVZ69_000298"
     CDS             31415..32974
                     /locus_tag="IVZ69_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8182417.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            32971..34335
                     /locus_tag="IVZ69_000299"
     CDS             32971..34335
                     /locus_tag="IVZ69_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP8182418.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            34506..35576
                     /locus_tag="IVZ69_000300"
     CDS             34506..35576
                     /locus_tag="IVZ69_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182419.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            35591..36259
                     /locus_tag="IVZ69_000301"
     CDS             35591..36259
                     /locus_tag="IVZ69_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182420.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            36279..36857
                     /locus_tag="IVZ69_000302"
     CDS             36279..36857
                     /locus_tag="IVZ69_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP8182421.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            37260..38171
                     /locus_tag="IVZ69_000303"
     CDS             37260..38171
                     /locus_tag="IVZ69_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP8182422.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(38427..39344)
                     /locus_tag="IVZ69_000304"
     CDS             complement(38427..39344)
                     /locus_tag="IVZ69_000304"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HAP8182423.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            39546..39983
                     /gene="zapA"
                     /locus_tag="IVZ69_000305"
     CDS             39546..39983
                     /gene="zapA"
                     /locus_tag="IVZ69_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HAP8182424.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            40041..40571
                     /locus_tag="IVZ69_000306"
     CDS             40041..40571
                     /locus_tag="IVZ69_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010781150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HAP8182425.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELW"
     gene            40703..43063
                     /locus_tag="IVZ69_000307"
     CDS             40703..43063
                     /locus_tag="IVZ69_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HAP8182426.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            43150..43464
                     /gene="trxA"
                     /locus_tag="IVZ69_000308"
     CDS             43150..43464
                     /gene="trxA"
                     /locus_tag="IVZ69_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HAP8182427.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            43646..45424
                     /gene="uvrC"
                     /locus_tag="IVZ69_000309"
     CDS             43646..45424
                     /gene="uvrC"
                     /locus_tag="IVZ69_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HAP8182428.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            45569..46468
                     /locus_tag="IVZ69_000310"
     CDS             45569..46468
                     /locus_tag="IVZ69_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182429.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            46461..47723
                     /locus_tag="IVZ69_000311"
     CDS             46461..47723
                     /locus_tag="IVZ69_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182430.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            47886..49784
                     /locus_tag="IVZ69_000312"
     CDS             47886..49784
                     /locus_tag="IVZ69_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HAP8182431.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(50083..50802)
                     /locus_tag="IVZ69_000313"
     CDS             complement(50083..50802)
                     /locus_tag="IVZ69_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HAP8182432.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            51139..51471
                     /locus_tag="IVZ69_000314"
     CDS             51139..51471
                     /locus_tag="IVZ69_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182433.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            51458..53461
                     /locus_tag="IVZ69_000315"
     CDS             51458..53461
                     /locus_tag="IVZ69_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HAP8182434.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            53480..53950
                     /locus_tag="IVZ69_000316"
     CDS             53480..53950
                     /locus_tag="IVZ69_000316"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HAP8182435.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            53971..54555
                     /locus_tag="IVZ69_000317"
     CDS             53971..54555
                     /locus_tag="IVZ69_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HAP8182436.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            54570..55556
                     /locus_tag="IVZ69_000318"
     CDS             54570..55556
                     /locus_tag="IVZ69_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HAP8182437.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            55546..55857
                     /locus_tag="IVZ69_000319"
     CDS             55546..55857
                     /locus_tag="IVZ69_000319"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HAP8182438.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            55879..57660
                     /locus_tag="IVZ69_000320"
     CDS             55879..57660
                     /locus_tag="IVZ69_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HAP8182439.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            57653..59029
                     /locus_tag="IVZ69_000321"
     CDS             57653..59029
                     /locus_tag="IVZ69_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HAP8182440.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            59036..59671
                     /locus_tag="IVZ69_000322"
     CDS             59036..59671
                     /locus_tag="IVZ69_000322"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HAP8182441.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            59701..61056
                     /locus_tag="IVZ69_000323"
     CDS             59701..61056
                     /locus_tag="IVZ69_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HAP8182442.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(61248..62642)
                     /locus_tag="IVZ69_000324"
     CDS             complement(61248..62642)
                     /locus_tag="IVZ69_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP8182443.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            62734..63705
                     /locus_tag="IVZ69_000325"
     CDS             62734..63705
                     /locus_tag="IVZ69_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HAP8182444.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            63702..64484
                     /locus_tag="IVZ69_000326"
     CDS             63702..64484
                     /locus_tag="IVZ69_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HAP8182445.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(64653..65024)
                     /locus_tag="IVZ69_000327"
     CDS             complement(64653..65024)
                     /locus_tag="IVZ69_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP8182446.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            65158..65601
                     /locus_tag="IVZ69_000328"
     CDS             65158..65601
                     /locus_tag="IVZ69_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP8182447.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
BASE COUNT        22092 a        10902 c        13634 g        19027 t
ORIGIN      
        1 tagatccaga ctattatcaa ccacaagaag tttttcgaga gtttagaaat cagattattc
       61 gttcaagtaa tattgaaaat tgagtcaata aaagaagcgt tgaagaaaag ttccttcttt
      121 cgacgcttct ttttaaaaga ttttacaaat gtcttatgga gatttgcttc aatgactact
      181 tgtagtcatt tcgtttaaaa taattatgtt acacccttat gtgtcacaga gaaatactga
      241 tataataaga aataaggtat gtaacaatag agtatacttc tatgttacat attgattatt
      301 ttgaaaaaat catattagga gaatataatt atgagaagtg atagtaggtt ttttgtcagt
      361 aatttacaag atgacgagct aataaggcag attgattcat tattagaaac aataacagaa
      421 tctgataaaa gaatattttt aaattatgta gaattaacac gtcatattat agagttggat
      481 aaacttttta atgtgtttag atataattta actaatttgc tcaaacactt cacaattttt
      541 actaatgatt taattgaaag tacaggtgaa aaattaacgg aagaccagta ttattatcag
      601 ataaatgctt tgacgataaa cttaattagt tcagccaaaa ctttgactga atccattgaa
      661 gtttgtatga aaaacttttt agcagaaaaa gattttaaat cttttaagaa taaaattctg
      721 agtaagcctt atgatgagca tttttcgtat aggtttttat tacatatgag aaattattct
      781 cagcatggtc atctgccagt aaatattcat caacaaagag tgtactttga tttggatgaa
      841 attctagcaa tgcctcattt tgattttaac ggacaattaa aaaaggagtt agatgtttta
      901 aggaaagata tatataacca atttagagat tccccacgta tctcttatgt ttatacagta
      961 gcgaaattta atttagtaat aaccgaaata tatttcaatt atttaaaaga gatcaaacct
     1021 attttaataa agttgaatga cgagaaaaat gaattactac tcaataccaa atttcagtta
     1081 attaattcag atggaagctc aagtgatatg cttttttatg agtttgatgg tgagaattat
     1141 cactgcttca accgaaagga caacagtata tctatgtatg ctgacataaa aagagaagtt
     1201 aaaaaaatat taaaagtaga agaacaatac tataaagaaa tagaaaaaag aaaccagtaa
     1261 ttaacacagt tatcaaggta aagaaaaagt tctctttctg tttgctagtt gtggcttatg
     1321 tagcaaatat caagttaata ggaaaattaa aattgttgaa aggaaagaag ttgatgacat
     1381 attagtaagc aagttgttga atatttatat tatcctaaaa aaggaagaat ggaaaatatc
     1441 gaagaaacct ttctgaaagt gttgtcacca tatattagtg attctatctt aagatttcag
     1501 gagcaggaaa aaaattataa atttggcttt gacataaaga actataatga ttcgttacac
     1561 gtagtatttc aatataataa gactggtaag ataggaataa aagaggtaca tatatttcaa
     1621 attttcctag ctaaggtcaa tattgaagca agtaaatcaa aattaaacta cactaccctt
     1681 ttagatacaa atgcgttgtt tttttcgaaa aaactattac cgtatttgca tagttacgaa
     1741 tgggcattaa gaaaattaat ctatttatta gctccggcat atttttctga taactgggca
     1801 gaggaatcaa ttccaaatga aatcatttcg tcaataaaaa gaaaacaaat acaagcaata
     1861 ggaaagtttg actcaaagaa tcttttacaa tggatagatt tatatgattt tgaagaatat
     1921 ctctttggag aaaattatat tttagttaca caagaaaatg aagagaatat tgtaaggtat
     1981 aaagaaatat ctcaggatca attattgaag ttatttcaag ataacagtca cactatatct
     2041 gattcatatt ctttgtggag tgaagtattt agtaaatata tggatgttaa gctagaagaa
     2101 attcaaacag acatgagttt aatcagagaa ggtaggaata ttgtaagcca taacaaagaa
     2161 atagaaatgg ctttatacca aaaattaata aagaaattga agagatatac aaatcaacta
     2221 gagaaagctt ttcaaaaaat attggctgga gatattgctg gtgaggacct tagtgatatg
     2281 tcagatgatt ttgaaggata tattggaaat tattttagta atatcgattt agcaggtgtt
     2341 actaaattgt cagagtctct atcagcaatg aaagtattaa atacagattc catgaaaaag
     2401 tcgatggagt caataggtca aacattatca gtccagcaag aaattatgca gaactttgat
     2461 actgaaggta tcagaagggc aacagaggga ataaatcaat ctctacaatc aataaaaata
     2521 ttaaatacag attccatgaa gaggtcgata gagtcaatag gtcaaacatt atcagcttta
     2581 tcagctcagc gagcaatcat gcaaaacttt gatactaaag gtatcagaag tgcaacagag
     2641 ggaataaatc aatctctaca atcaatgaaa atagtaaata cagattccat gaaacgatcg
     2701 atggaatcaa ttggtaaaat ttcatcaaca aaccaagtat tgaagtcaga gtaaataaaa
     2761 caggaacgat ggcaatcatg ttaccacacg aaatgctatc atttgtagca agtattggat
     2821 ttagagtaat tattatagag aggatgagat aaaatggttc aaggactttt tggtggaggg
     2881 acttcttatg aaggtcaatc gatttcggac attaaggaag acgtcaataa ttggaagata
     2941 tatacagaaa atgtaaaatc acagattgtt gaaaaaaaag aggctttaat taagaatggt
     3001 ttttggaaca aaataccatg gaattttcaa caaactatta atgaatcaat cttctgttta
     3061 ggaacatttc ttagtgattt tcagatagtt gaatcagctt ttgaggaaaa ttttatttct
     3121 gagagagaga taaaacttct aaggaaaatt ggtaaaaatt ctgtgcaatt taaccatagt
     3181 tacggaaaat actttaagga agaatacgaa tggcgcgaat atggaaatcc agaatttgaa
     3241 atcgttgaat caatttacca acatgggaga gatttttttg tgacgttaca agatgcaagt
     3301 aatgcagcag gacgactgga ggactatatg agcaacaatt caatatataa taaagtaaat
     3361 atatttggaa atagttacaa cactaatata cagcaaggcc acaataataa tatgattgtt
     3421 tctattgatg atatgtcgga attattatca aagcttgatt tgcttttgga gaatttgaat
     3481 gattccttac ctgaagaaga ggtagaagag gctcaggagt atatcgaaac cattaaagat
     3541 gaagctatta aagaaaagcc taaaaaaact atgctgaggt ttgcggtaga tagtctaaaa
     3601 aaacttaaat ggagtacaga attcttagct tctgttgcaa caatagctca acttgttgct
     3661 ccactgctat aagtggagaa tgaggtgttc ttcaattaac cgacttgcca agttgtggta
     3721 atggtttgag ataatgaaag ctttgtattc tatagagatt gatgtatctg aatgaatgct
     3781 tgtttttttg gatatagctg attaatcagt ggtgttacat tatttataag tcgtttgatt
     3841 aactagttct tacgatttct tatcaaaagc acgccacgca acttgaatac gtttttgaat
     3901 acgactaaaa aaccacttaa ggtgaattag acttaataaa gtgattagtt ctattcaaaa
     3961 atcgttgaaa taccaactat cgtcaattat ctttaatgag cttaacttca tggcggaaga
     4021 agaagaatag actataaagc taggagaaac cttgatatga tagggtttct ccttttttta
     4081 ttttttactg tatgccatat tgtatgccat ctagtcaata tttaagtgtt gtactaattt
     4141 ttcaacagtc ttttctttcg tttcttttgc caagtgaccg taacaatcga tcgtctgact
     4201 aatttttgta tgccgtaatc tagtttgaac ttctaccata gtagctccag cgtccaagag
     4261 cattgaagca tgagtgtgtc ttgctacatg cacaccgaga aatggaacca tagctttttc
     4321 acaaatagta atcaatcttg cataaatagc gtggtgtgtg attagttctt tatagatacc
     4381 acaaaaaatc atagtcggat cagttacacc aagtgtcagc atatatttcc gctgattaat
     4441 ctgccatttt tttaatatag aaattgttct ttcatctagt ggaagaaccc cagcactaca
     4501 atcagtttta ggatcactga ttttatagcc atttttggat tggcttagtg ttttattgat
     4561 ggtgaccgta ttttcttgaa aatcaatgtc tgaccaattc aatgcaaggg cttcactgat
     4621 cctaaccccg ctataaaaga gaaagcgtag taacgtttta tcaaagtcgt ttcgataagt
     4681 ttcaggtttg ctgtttaggt aatcaaacaa ggtgatcagt tgttctttac tgtaaacttt
     4741 gaccttttct ttatgcttag tggtggttct tttaggcatt aatacgttgt ctagtggatt
     4801 agtctcaata atcccaagat tgatagcgta gctaaaaata cgcttagaag ttgaatgaag
     4861 taccttgtat tggtcagtag tttcagccca gctatttaca atttgttggg ctttttttac
     4921 cgtgacttca ttcacacgaa gatttccata ttttggaaga atccactttc taaacttgat
     4981 ttcagttttc atgaaggtgg cttctcggac agtggtttta tatgtttcta gccacaagtc
     5041 ataaacttct ttaaacgttt cgttgttcgc ttttttaata ccgtttttat cgtagtccac
     5101 ttgcaagcgt gacaaggcaa gctgggcttc tttttttgtt ttgtaacctc gtctacgaac
     5161 cttatcaggt ttgccagtca ttttgttcat tccaagatag gcttcataga gccaaaattt
     5221 acctttttta gtttcatatt gcttgaatgt tgccataata gttttccctc catagtgtag
     5281 caagccgtgg gggcggttgg aggaggcagt ttattattat tttgaatagt gtttatttag
     5341 ctcagtaaca agagctgtga actcttttag aagatcattt tcataaaatt cttgatactc
     5401 ttttttctca tctgtatttt tttctgaatc attaattaat gagtcatatc gtaaaagcgt
     5461 atttagaaga gctgcgagat aagcaattgg ggtactcccg tcaggaaatt caattcgaga
     5521 tcctgtttta agatatttta ttgcgtttgt taaataaatc ttctgtgaga cagtcaggtt
     5581 atcttcttcg atgttattga tagcattaga aagattagaa tcaattatag agttattttt
     5641 ttcaatagtt tttttcaatt gcttttcaag cacatttcgc ttaatttcgg gcatcatatg
     5701 catatctctt aatgtataag atccgtttaa tagataggta gtggatacat ctaatacctt
     5761 tgaaagttgt ttaagcctgg tgttattggg aagattatag ccattttccc aattactaac
     5821 ggcaccttta ctggccggtg gggataattt acctccaagt tgttccattg agagtccctt
     5881 ttcaattcta gccagtctaa ttctttgtcc tgtctccact gcttcggggt atttttttct
     5941 agccacattt tcaccaccat tcatatattt tctctactat atcacgattt aaatatgtgt
     6001 gaaacataaa agttcaaaaa agtatgttaa aattcttgca aatgaaaagg tatgatggta
     6061 tattgagttt ataagaggta tagaaatgta ttcaagagcc tcttgcattt ttttaaaatc
     6121 tttgtataga aatgtatgct aacgaggggg gataaatatg gaattaaaaa ttgacaaact
     6181 cacgcttgat gatccagctt ttaaaattat tgacgatcga gttgttcaac aagtagagca
     6241 aactcaagga acgttacttt cattattaga aaaaaagtac cagtttccaa aatatatgaa
     6301 caaggcacaa gctgctaagt atatgaacgt ttcatacaat actatgatgc agaaatatgt
     6361 tcctaacggt ttaaagttga ttatagttga tggagtcgta agaatttcac aagatgaatg
     6421 tgatcgcttt atggaagaat accaaaaata aacgcaagcc gtgggggcaa agggattaat
     6481 aggaggaaat aataatggaa tcgacacaaa ataaagcaat cgaaaaagta ttatcaacaa
     6541 ttcttacaga agacacagcg gcagaattag caaacttgga aggcaaagcg ctagaagaaa
     6601 cgtttgaatg tttgtacgaa caaatggact atcaaaaatt gctaccacaa gaaccaacgg
     6661 taagcggagt attgcgtggc ttgaacgatt tagtacaagc agagtttaaa gaacgacttt
     6721 ctattgaaga gtatcaagaa attttgtatc agcaagttga gttgttagcg agcttgctag
     6781 ggcttgaact ggaggacgtt gaatgaaaac tgaaatttgg aacggacaca ttataagatt
     6841 tgtcgatatt aatgatgaat ggtgggcagt ggcgaaagat gttgcggaag cgttaggtct
     6901 taaacaggtt actagagcca ttcactcttt gcctaaagat ggggttacta ctagtaaggt
     6961 catcgattca ttgggcagaa cacaagatgt aaacatcatc aacgaaaaaa aatatttacc
     7021 gcatggcatt caaaagccgt aaaaaagaag ccgaggcatt tcaagactgg attttcgaca
     7081 tcatcaaaga actacgccag tccacaggac ttgaaggctt tcaagtattc cgcatgctag
     7141 acaaagaaca ccaaaaagaa gcaatgacta aattaagcca cgctattact gaaccaaaac
     7201 cagtagacta cattaaagcg aatgtgatag ccaataaagc tgtatcaact atttatggtc
     7261 attccaaaat ggtaaaaaag aaagatatga ctcctgaaat gttggttgat cgtgaaccta
     7321 ttttagatga gacagtagaa ttaatgactg ttaaagaaaa atatgggttg cagttttcag
     7381 tgagtgagaa aatttataat cgttctgctg aattgcagac aacttaggag cattaacatg
     7441 atcgagaaca aagaaaaagc cttatccata acagtcttgg cggacaggat aaaggcaact
     7501 taattgggat aaaacccgat attctttgtt ccgattatac catattaaaa aatcggaggg
     7561 aaccattatg aaacgaaact taattatagg aagcatttta atcggcggaa ttttcggctt
     7621 attaccatta attgcaaaaa tagctatctt tgcaggatta gcgttatatc tcttcactgc
     7681 ttatgacgag tacgactatc aattaagaac tggagggcat aagtagatgt acaaaacaaa
     7741 actattaaac caactcgata gccttgaatt agaggaaatt aatcaaggga tcgctgaact
     7801 agaaaataat atcgggaaaa cctactttgg aaattcattc aatgaaaaac taacagtttt
     7861 gtatgtactc aaaaaacatg cagaacacaa aataatttgt cgagaaatca acgagctaaa
     7921 aaatcagatt ttaaccgcat ggttaaacat tactgatatg caagaagcaa gggtgaaaac
     7981 atttaataca tgggtaaagt atcagaatca attaaaaggt gctgaatttg ttcgggatgg
     8041 gttgaaatac gaacttgagc agttgaagct catggaggtg tctgaatgat ttataccagt
     8101 attttgaaaa aggaggagag gtttattggc aaataattat caagcagcaa cggaattaca
     8161 aaagtcggga tggtcaattt atcccttatc tcctggaact aaaattccaa taaaaggctc
     8221 tagtggttgg aatgatgcaa ctaacgattc taatcaaatt aatgaatggt ggacggaaga
     8281 tgcaactaga aatattgggt taatgcttga agatcatcaa atggtggtag ttgacctaga
     8341 tcaacattct gaaacacgaa acggcgttga gaattataaa aaacttgctt caatgtatga
     8401 tccatttcct tctacttata cggaaatcac accaggtaaa ggaatccatt tcttctttaa
     8461 aattcctgat ggtgtaatta tccaacaaga aacaggtgca tttgctgata tcttcgggcg
     8521 tgatgataaa ggtaaaagtt taagcgggat tgatattatc actaaaggag ttccaatagc
     8581 gccaactatg attatttcaa gaagtgttgg gagagcatat gaacctattg aaaacgtatc
     8641 tctaaataat attgcaccag ctcccgattg gctagtgaac ctactgctaa aaaaaccgca
     8701 agaaataaag actcaatacc gacccgtagc aaaaacaggg acagcaaaaa aattagatat
     8761 gattgttcaa ggcgctggcg aaggtagtag aaacgatcat ttaactaagt tatgcggttg
     8821 gttactatgg cacggtgtag ataatcaaac tttagcagaa ttgatttata cagcaaatgc
     8881 gtacaatgaa ccaccgctaa aagataaaga agtgaatcaa attattcgat cgatgattaa
     8941 aaaagatttg agggggaaag ctcatggctc ataagcataa attagatagt attttagact
     9001 ttcccgaagc cagcgagcgt gaagacaata tcattgaatt gaaaacctgg atgtcacgat
     9061 taagatgcaa taaagacgat cagattaaaa gtaacagtgt tgtgaatgca gaattgattt
     9121 taaccaatga tagcaattta gctggaacaa ttgcttataa cgaatttagc ggatacattc
     9181 acctattaaa agattctcct tggatcaatc gtaccgctgg agaatgggaa gacagttttg
     9241 aggatgcctt aacggcatat attgaagaaa actacaatgt agtttttgat gacaacaaaa
     9301 tacacaaagc agtagtaaat gtggctagaa agaatgtttt caacccagta aaagaacgta
     9361 tcgaaaaagt taaatgggat caacagccta gactggaaac actgtttatt gaccttttag
     9421 gggtagacga caacctttac acacgagaag taacaaaacg ttggatagtc ggatcagtcg
     9481 cacgtatcta taaaccagga ataaagtttg agatcgttcc agttttggat ggaccgcaag
     9541 ggattggtaa gagtaccgtt ccagcattac tttacacgga tgattttttc accgattcat
     9601 tagattcgct aggtgaaaag aaagatgatt atatgcagct tcaaggcaat gtaattattg
     9661 aacttggaga attatcttca atgaacaaaa ctaaaattga acagataaaa aacttcatca
     9721 gtgccaagat cgataaaatt agacctcctt atggtcggaa tgtcatagct tgggcaaggc
     9781 aatgtgtatt tattggaacg tcgaatgatg ggcagtattt gaaagatgat acaggaaacc
     9841 gccgttttta tcctttgcct tgtaagaata agccaaagat gaatccgttt aaaacaaagg
     9901 atgaatattt tcttcaagtg ttagctgaag caaaggtgct ttttgataaa ggacaacgaa
     9961 tctattttag tcccgatgaa gataaagaag tcttagaaat tgcaaaagac tatcaagagg
    10021 atgccaagat ggagaatcca attaaagaag caatcactaa atatttggaa atggaaatcc
    10081 cgtataaatg ggaagaagct ccagcgtggg cgagacgttc ttattatcag aactatcctg
    10141 acagtaaatg taatgagaaa aatttacagc atttctataa tggagctact atgcaacaag
    10201 agttttattt agttgatagc gtactcaccg ctgatatttt ggaagctgtt tttgataaac
    10261 aagcaaagga tttattgaat ggtcgatcag atgcagaaac taaaaagatt gccttgatta
    10321 ttagcagtat tcctggttgg gaacggaagc aactgccaaa aagaaataaa cgacgaggat
    10381 tttacaataa gtcaaatgcc tatgaaaata aaaatcgagc tggaaagtac aaaaagtaac
    10441 gggtagtaac gggtcagtaa cacctagccc gttactagtt tacccttact gccccaaggg
    10501 atacagcaat ttggtaacgg ggtaacacct tatttcctta aaacttttga aatagttagc
    10561 taatatgctg gggaataatg ttactggatt ttacccgtta cctgttacca aaacgctaga
    10621 acccttgtcc ccgttgggat tgagtggtaa cgggtacctg ttacgtaggt gttaccacgt
    10681 gttacgaatc aaggaggaaa gtaaatgctc aatattattt caacaaacaa agcaccgaac
    10741 tttcaatata cagatgaaat ggatcggttt ctaatgaaca cgctggcatt tagtgtggga
    10801 ttggtaacag aagattattc cacatttgat ccagaagtat taaagataat ggaagaagaa
    10861 cctgattggc tgcaggagtc agtagcgtgg tgtcaatcgc tagtagtggg atcattggta
    10921 gatagtggca actatgatga tacaggtgag ctaatggatg aatttaattg tctgcttaac
    10981 ctatatgatc gagcgagaca acgagagctt acatcgaatg aggataattt gtttttaaac
    11041 atccatgata agttcttggc tttgctacta acagatgatg aattgataac taatttattg
    11101 gaggtagaat aattatgcat atggaaagta ttagatactt cgatggtgag aaacacattg
    11161 agtattcaaa cactcaagaa gatgtagact ttattagttt tgaggaagat aaaatcacta
    11221 aagttaattt taaagacgga acgtgcttga agatagtttc gccttatatt gaatacaaat
    11281 caaaatggga acaagatgat tctgacgaac gagatcgctt tggttggtaa tctatggcag
    11341 ttaaaaaaca atgtaatcat gctggatgta aaacattgat tgattatagg cagaagtatt
    11401 gtgggaagca taaagcaaag caaacggcaa ttaagcgtga agaaagaaag caaagcgaag
    11461 gtaaatattt tcaattctat caaagtagaa catggcgaaa ggcttcatac ttgtatcggt
    11521 taaatcatcc agtatgtgag gattgcctag aagaaggctt gataaggaaa gctgatgttg
    11581 tagatcacaa aattgaacta aaagatgatt ggaatagacg gttagatgaa actaattttc
    11641 gttctttatg ccatgcacac cataattcca agacagccaa tgaaagacaa agacgagaaa
    11701 agagtaccct ttgagttaag ggggcatagt gtgaaactta ctgacaatcg atgcctactc
    11761 attttggtac aaataaccgt tgtgaaaagg cataagggta attacaaata acgattacac
    11821 ttgtaatcac aagtgaaaaa gtatataatg aaagtaggag atttattgaa aaatacaatt
    11881 gttattactg ataaaacagg gaaacagcgc accattgagt tacctcattt tggtcaagtg
    11941 accattcaaa tgcagaacgg aaaaatcatt tatatagata aattagataa agaaaaattc
    12001 tgatcgaaaa acgaaggaat gtgagcttaa ttgcttacgt tcctttttct tttgtctgaa
    12061 aggaggacaa catgggacac cctaaaatat tacacgatac aaaaggcaat atatcaagtg
    12121 aagaaaaagc aatccgtgtg gacgctagag aagaattgtt caagcagcaa ccattaataa
    12181 atatcacgcc ccctgactgg atggcagcga gcgctagaag tgaatggaat cgtatcgtac
    12241 caacattaaa aaaagattat ccattgagtg aagcagatta tggttcattg gtagcctatt
    12301 gtttagcctt tgctcgaatg aaaacagccg aagccgagat aagaaaatca ggtacgttta
    12361 tcacatgcga aaacggagta aagaaagcca atccagcggt tcgggttcaa tcacaagcta
    12421 tgagtgattt gaaaaaacaa gccacctcac taggtatgac cttagaatca cgatcaaaac
    12481 tagctttgaa caaggttaaa aatgatgaac ccgaagaccc gttcaaagag ttgatgaatt
    12541 catgaatgat tacattgaga aagtcctatc aggtaagctg attgcaccca agaaaattat
    12601 ccaagcgtgt gagcgtcata taagcgattt ggagcgttct aagtcagata gcttccctta
    12661 tgtgttcgat gaagaacaag ccaccaaagc gattaaattc attgagttgc taccatctac
    12721 ggacggtaaa gcaatcaaga tgttaggatt tcaaaaattc attctaggca gtctttatgg
    12781 ctggcgtact aaagaaggga attacaggcg attcaatcga gcgtttacca gtatgagccg
    12841 taagaatggg aaaacgtata tcgcaagtgg catggctgcc aatgcgttga ttatggaaca
    12901 agaaccagca gaagcaaggc aagtattgtt tgtaagtaac gctttgaaac aagctaaatt
    12961 gggctatgat atgctgtcta attcacttag aaacgtggtc aagtctagta agtttttaag
    13021 accacaactg aaaattatga actctaagat tcagcacttg ccctctaatt cgttcgctat
    13081 ggcactggct agtgaaacca gcacgctaga tgggtttgca ccaacaaccg caattcttga
    13141 cgagtggcac gaagcaaaaa ctcgtaaaac gtacaacgtc attaagtcag gaatgaccca
    13201 acaaaagaac ggcttattgt gtgttattag taccgctggg cttgatttaa acgttcctat
    13261 gtacgaggaa tacttattgt tagatcgtgt gctaaaaggc gaagaacaag ccgacaggta
    13321 ctttatagcg atatgggaat tggacgatcc cgaagaaatt cacgatcaag agaaatggat
    13381 caaagccaat ccgatttttg aaagtgaaga aatcaaaaaa gtaatgattc caaccattca
    13441 agatgatgtg aaccttgctt tgaaacaaaa taaccttaat tctgtattgg tgaaaaactt
    13501 caatttatgg agacaagcga gtgaggacag ctatatgatt gctgaagact ggcaggcaac
    13561 cgaagtagaa ccacaagata ttacaggcaa gcccgtttat atcggagtgg atttatctaa
    13621 aacagatgat ttaactagcg tttcatggat cgtaccgcta gataacggcg aactttattg
    13681 tgattcacat agctttgtag ccaccaaata tgggcttcaa gacaaagaaa agcgcgacgg
    13741 tttgccttat cgagaactag aaaaagctgg tgagtgttcc attactcaat tagaaagtgg
    13801 aatcgtggac tatgaccaag tatttcagtt tattcaagat ttgattcaag aaaatgattt
    13861 ggaatgtatg gggatttgtt atgacccgta taacgctaat tcgcttatca gtaaagctga
    13921 aaaagccaac tacccaatgt tagaagtaag acaaggaacg attactctaa acgttccgac
    13981 ccgaactttt agagaacaag tttatgaagg caacgttatt cacaataaaa atacgattct
    14041 cacccatgca gtgaacaacg ctattttaaa aacggataac aacggcattc agattaataa
    14101 atcaaagaac agtaacaaaa ttgatccaat agctgcatta atcaatgcct atgtgtttgc
    14161 aatggattac ttcaccacaa cggaaggagc gaaagcagac aatgaatttt atacaagtga
    14221 agaattttct ttctaattac attcataccg ttcttttact tcttggattg gtgtgtgtgt
    14281 tggttgctat caccttacta acaaatgtct actatggctt gttagcgctg ggcatagtgc
    14341 ttattggggt agcggtcatg ctaaatacag aacagaaggg aggttaaaag atggcatttt
    14401 ttaaagcgag acaaaataca acgggagatc ctttcctaca acatgtggta tcaatccaat
    14461 cggatgatta caccaccagc tttacaagcg ttcgtgcatt aagaaatagt gatgtgtttg
    14521 cagccgttcg aattattgct agtgatattg cttcaagtcc gattcaattg gtcaaaaaca
    14581 atatgccaca agctgataat gaactggtga agttactaaa cgagaaacct aattcagaaa
    14641 tggatggttg gcatttaaag tttgctttgg cggtcaatat gttgctaaac ggtaatagct
    14701 ttgcagagat taaacgcaac ggtgaaaagg tagaagaaat tcacttatta cctaactcaa
    14761 gtgtaacggt tactcaatta gataatggta cgttgtctta tcagattggt gataaaaaaa
    14821 gacgtgtgaa gtctagcgat attttgcact tcaaatattt cacccaagat ggtttaacag
    14881 gattaccacc actttatgcg ttacgtgatg aactgaaaat tcaacaagct ggcaaccgca
    14941 cattgcacaa tttctttact cgtggtgtca gtgggtcagg tattttgaag gttcataagt
    15001 cagatttaga cggatcagca aagaacgcaa ttcgtgaaaa gtttgaagaa gccaacggtt
    15061 caagtagtgg agataatgct cttagaacga tcattcttga tgaaacaatg gactacaaaa
    15121 cattagaaat aaacaccgat gttttgaagc ttatcaattc caatgattgg aacacaaaac
    15181 aaattgccaa ggcgtttggt gtaccgattg agcgtttagg cgttgaaaat gaacattcta
    15241 gcaccgttca aagtaatctc cagtatatcc aaagtacgct gattcattac tttaatgtgt
    15301 ttgtgagtga attagatacg aaacttgaaa ccaatatccg ctttaattcc gatcagttac
    15361 tagagactga tcctgaaaca aaagtaaaaa atgtattgga tcaggtcaaa gggtcacttc
    15421 tcacgattaa tgaggggcgg tcgaaaatgg ggctaccccc catggatggt ggcgatcgtt
    15481 tactagcaag tttgaacttt acgtatttag atacgttgga gaaatatcaa ttaaaagaac
    15541 aggaaggagt tacaccagtt gaataatgaa gaagaaaagg aaaaacggct gacagaagaa
    15601 gctgagctaa cagccgattc tcccaaagta gagaaagaaa atgaaaaaca accaacagac
    15661 ggcaaaacta tttcaggcta tgcgttgaaa ttcgggcaac cgtcaaaaga tttaggcggc
    15721 tttgtagaag tgattacacc cgaagcatta aaagaggtgg atttatcaaa tgtgttctta
    15781 ttatatggac acgattattc aaagccacta gctagtgtca aagcaggtac gttgaaattg
    15841 aatgtcgatg atacaggatt acattttgaa gcagagctaa ccgacacgac ctattcaaat
    15901 gatgtgtatg agaatatctc aaaaggggtt gttgattcta tgtcctttgg gttcgtgctt
    15961 ggattagatt cattcgacaa aaaagaagat ggcacaattg aacgatcaat agataaaatc
    16021 aaagcactta atgaaattag tgtcgtgacc gttcccgctt atgattcatc aaatgtccaa
    16081 gtaaataagc gttcttacga atcgtttatg agtaacaacc aagcaaaaca aacaaacaat
    16141 agcttagaat ccacttctaa agcacaaaag gagagtaata acatggaaaa aactttaatc
    16201 gataacgaaa aaacagaatt gcgtgggtat gaagaatata tccgttcaca aggcgaagtg
    16261 cgtgatggag tcactactgt aaatgcagcg gcagttgttc ccgaagaagt aatcggtgaa
    16321 gtctttgatt tgaaacgttc aaattataac ttagctcaat atgcaacagt aaaaacagta
    16381 tcaaatggac aaggtaaata tccagtagca actaaccaac aagcagtgtt agcaacaaaa
    16441 gctgaacttg ctgaaattgg tgatattgac gctgaaatgt ttacttcagt tgattataaa
    16501 gtagaaactc gtgctggtaa gattgcctta tcaaatgagg ttgtggaaga ttcagcagtg
    16561 aatattgtac aagaggtcaa agatcagtta gcgaaattgg tagaaaacac tgacaataag
    16621 catatcatgg atttattaaa aacattcact aagaaaacgg ctgctacgtt ggacgatttg
    16681 aaacaactat acaatgtggc attagaccca gcattaaata aaatggtaat tctaaaccaa
    16741 agcggatatt accacctaga tacattgaaa gattcagatg gacgttacat tttacaaccc
    16801 gatgtgacag cacctagtgg taaatcatta ttcggtatgc cagtagtatt gattgcagat
    16861 acattgtttg ccaatcctaa agctggaaca ttccctatga ttatggggga tattgcacaa
    16921 tctatctttg ttgctcgtag aaatcaagta acgactcaat gggaaaaatt cgattactac
    16981 tcacaaggac ttgcagtgat cgttcgcaac gattataaga aaattgatca aaatgcttca
    17041 gtgtatattg agtttacgcc agttgtaaca ccaaaagtat agaaaaatat tgggcggcgg
    17101 tttatcccac tgcctttttt tcattaggag agataaaatg gtaattttgg atagcataaa
    17161 aaaaagtatg cggatcgatc acactattga tgatgacttt attcaacaat tgattgatac
    17221 agcaggcgaa tatataaaaa gtgctattga tagtagcgca acggataaag atatggataa
    17281 ttatcagcaa tttgatttgg cggtgtcatt acttactcaa cattggtatt tgaaccgtca
    17341 agaagccagc agcgaacgga taccagtaac ggtacaagca ttagtacaac aaatgagagg
    17401 tgcttattat gccaatcatt aagaatgtaa atgaattgac tgagagagtc aagtttaaaa
    17461 agacaaaacg ggtaaaagat gaagatgggc agatggtgga tagtgaagaa actgtatttg
    17521 aatgttgggc taatgtgcgt tcacaaatgc taaaagacgt gcttgctagt gtaggtacca
    17581 ttcttgaagg aacgttgacg tttattattc gatacgatca agattatgaa ctaacaaacg
    17641 atatgaaagt agcttggaaa aacaagagtt ataaaattat ttcaatcaat gaaggaacgg
    17701 cgtttaaaga ttatacaacg atcatagcta aacagatttc ttagaatgat tacacttgta
    17761 aacgttgtgg gtatttagta taattaaggt agtaaatgaa gggttagctg cctgaatttt
    17821 gcaagactta gctagtcgaa atctattgtt ggactgaaaa ttgtaggtgt ggttgcaaac
    17881 atgctggact aagaaagatg atagatgatg aacgttcaat tttaatacag gcatgctagg
    17941 actgattgga tggttttggc aagctgattg tgtagaaatc aaagaacacg tctgttgtgg
    18001 acgtgttttt tttgttataa ttcaaaagag gtgatttaat ggacaaagca gagtttacaa
    18061 atttttattg gaagtattat ctacatttag aaaatgagtt tattaatacc acagattttg
    18121 tgatgctcga tgagaataat ttcaaaacat tctctattga atatcaaaaa ctactactag
    18181 cgattggttc ggagtgtgag attattttca aagaactttg cggatttgat agcagtagca
    18241 ataaaagcat aactgatttt aaagctgtta ttaaatctag cgaattaatg tgtttggata
    18301 atggtgttag ggttatgaat tctttaacat tgacttcact aaaacctttt ggagatgggt
    18361 ggcctgaaga tacaccagat tggtggaaaa tatataacag agtaaaacat ggtcgttctt
    18421 caaattataa ggaagcaaat ttggaaaatg tgttgtatgc tttagcaagt ctatatttat
    18481 tagaggaata tttgcataag aaagtaatac tagaaggtga agtagacttt ataagtccag
    18541 agtcaaatct atttacgtta tcttgggaaa gaaaacattc gtcgatgcaa aaagtgacgt
    18601 ttgaaaaagt ggattcaaat tatgtagctc cactcattga ttttaaagaa caagaagaaa
    18661 tttaaaaacc cccacggctt attgaagttt ttgtatgcca tattgtatgc catttggttt
    18721 aaatcgcttg aaaaatagtg atagataact ctaattcatt tagtcataaa cgctgttttg
    18781 ataaccttta tagttctttg atatgggttt ctcattcatg gcggaagaag aagaatagaa
    18841 caaaagaatg aattaataag atataaaaaa agggattgtg acaaacgtct tgtcacaatc
    18901 cctttttcca aataaacgat gttcaatcag ctgcccctcg gcattcgctc gaaaaacggc
    18961 gaaatatgaa gaactatttt gccatttgtt tctctaataa tcaggtcaaa acgttgactt
    19021 cacagtctct tccttaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt
    19081 caacaaacat gagaagctgt tttttgaaat tgttccttgt gactcggagc tgaacggcag
    19141 gctcacgacc tctttcttaa acggtgttca aaagcttgca tctgcggtaa taagttcaac
    19201 caaacgaaaa ttatgaggag ctatttttgt ttggctgttc ttattacttg atgcaggaca
    19261 gctttttcac aacctctttt cgtttagcac taaatttcct taaaaagtag aaaagctttc
    19321 gaagcctcgt ttgtttcttt tactgtataa taaaagaaaa gagtaacaat cgctaaaaga
    19381 tataaacaag agaaaggaaa tacaagatga ttggtctgat ttattttgtg gtgatcgttc
    19441 tggcgaacac agttggcgct atttccggga tgggtggagg cgtgttgatc aaaccgattc
    19501 ttgatcttat cggcgcccat tctgttgcag ggatttcttt ttactcaaca gttgcggtat
    19561 tcacgatgtc cattgtttcg actgtgcgac aagtatcaag cgggaaatca ctgaattggc
    19621 agattgtcgg ttgggtatct agtggagctg ttgttggagg agtagtcggc aacattgtat
    19681 tcgaagtttt tttacagtta tttgaaaacg agaagcatgt gcagctgatc caaatttttt
    19741 tgacggtatt gaccttggtt tttgcgttct tctacaccaa gcatcatcag ccaaaatttc
    19801 atttgacgtc atggacttgg taccttatat gtgggggggt tctgggcttt ttagctagtt
    19861 ttttaggtat tggtggtgga ccagtcaatg tttctttgtt gatgctgatg tttgcattgc
    19921 caataaaaga agcaacacta tattctctat ctacgatttt cttttctcaa ctggcaaaat
    19981 tggtaacgat tgctttaaca agtagcttta tgcgctttga tttatctatg ttgttttatg
    20041 ttatccccgc tgctgttatt ggaggtttgt ggggagcaag atttagcagg gttttgtctc
    20101 caaaaaaagt gacctttatt tttcaagtaa ttgtcctcgt ggttcttttg gtcaattgtt
    20161 acaatgcctt tgtcatctta caaacattag gagaatctag actaacgcaa gtcaaaatca
    20221 ctgaaacata ttgttctaaa tgaaaaaaag agtatactat gataaaaaaa ttcattttaa
    20281 aaaatcagaa attggctggt gatttggatg ttacgggaaa tgcgtttaga agatgcagaa
    20341 gcactacgtg aaatcaatgc ggatcaatta gggtatgata taccattaac cgttacggtg
    20401 agacaaatga agaaactgct gaaggagcca gagaaaaatt ttttcttggt ttatgaagat
    20461 cctacttcta aaaaagcagc tggctatgta caagcggagt cctatgaatc gatttttagc
    20521 gatccaatgt tcaatattat ggcacttgct gtgtctaaat atgctgaaaa aagaggcatc
    20581 ggaaaggctt tgatgactgg cgtagaagaa gaagcgaaaa aacgaggaat aacgacaata
    20641 aggcttaatt ctgcagaata cagagtagaa gcacaccaat tttatgaaca catcggttat
    20701 cattccgata aaatgcaaaa aagatttttg aaaatcctgt aaatctttat caaaaaaata
    20761 cccgatcacc aagccgatac ttgatgatca ggtatttttg tttttttgac taagaaagta
    20821 attgcatcaa gaaaccagag atgatcaaaa cgatggcacc accaagtcga ttgcccattt
    20881 gagcaaaagc aataagttcc atccgattag ctgcagataa gacggctaca tttcctgttc
    20941 cgcccatcga gttgttgcat aagccagcag taatagttga ttcaattgga tataaaccaa
    21001 acaaacgacc gacaaatcct gaaacaactg aaatcgcgat aacacttgtc agacataaga
    21061 caacaaattg ccatgtcaaa gcagaagcta atacattcag attcagcaac gcaataccga
    21121 taccggcaag aacagctgct gtcaagtttt tgacaatcaa gttattgaac atgatagctg
    21181 catcttcata atactctggt aataggttgg cgattttaca gatgacaacg ataataatca
    21241 taaatgcgta agcatggact ttaggaacaa aatagttacc aatttgtcct aagatgaaga
    21301 aagtcaatga taccatcaaa ccaacaccta actgtggaat ggaaggtttc acagttcgag
    21361 gttttccatc gccaagatcg cctttttcca ttaatttacc attgccgttg aattttggca
    21421 ttgattgtcc agcacgagca actaatgctg caccgatgat agctaagaca tttgtcattg
    21481 ctgtcgcagg aatcaggcgg gaaatgatag aagaagcatc cgtacctaaa acatttgcat
    21541 aaatcgttga taaaggaacg gctccggctc caacaccacc agccatcgca ggtaatgaga
    21601 tgtataaaac ggaatttgca aaaccatttc cgataagcat gcccacgagt cctacggcaa
    21661 aaaaggagac gaccattgaa ataagtgcaa cgggaataaa acgaacagaa gctttcatca
    21721 atagattacg gttcatacca aggatgctac cagtaatcaa ggcagcaata taaaagtccc
    21781 aaaagcccat attgctgaca aagttttctg tggatttcac tacatattca ggtaagatcc
    21841 caaatgtagc aatcgcagca gaagcgaaga tcgcaaaaac ggaaccacca cccaaataac
    21901 ttttgacgat agggattttt gtcccgataa aatgaaataa attaccgaaa ataaccaaaa
    21961 ctgcgattgg tccaatcata ttcgtcggta atttccctaa agccattgca atgatcagga
    22021 caaggaccat gatcaaataa agtggcaaac ttacgccggt gatttttgtg gaccaaaaac
    22081 cttctttttt cttttcctca actgcagttg cagttgttgt tttttgtgcc atttttacag
    22141 atcctttctt attctgtatc atatgaaaaa agccaaagaa aagcgacaaa agagcaggag
    22201 ttggctggcc gctgttttgc cgcagtcgct tttttctttt tagacgtcat acaaagtttc
    22261 tgtatgttct tttactataa cgatcttaat cttctaaaga tttatattca ggaacccatt
    22321 tagcagattc aactgcttct ttgatatccg tgatttcttc acgattcaag ttttgtgcga
    22381 caactgattt tgcgacagtt tcagcaatcg tttgagaaaa ttcagtgatt tttgctactg
    22441 gaggcaagat agctgctcct ggttttgtta catcaacgat tccgcctaat gctcgactag
    22501 cttgagaaat gatttcagca tttactcgtg tagctgttga agcaatcaaa ccaagtccta
    22561 aacctgggta catcaaagca ttatttgctt gaccgatttg gtaagttaca ccattatatt
    22621 caacatcagc agcagggata cctgttccaa ctaatgcttt tccgtccgtc cattctatta
    22681 aatcttttgc ttttgcttct gccaattttg ttggattaga caaaggcatg atgatcggac
    22741 gtggtgtatg agcagccatt tctttcacga tttcttcagt gaatgctcca ggttgggtag
    22801 aagtaccaat catgattgtc ggatggatcg cttttacaac tgcttctaag tttgtcaatt
    22861 catcagcatt agtgaaatct gagcgtttgc gagcgaatgg gatttgacca ggagtcaatc
    22921 cttctgtatc ttcaaacaat aaaccttgtt tatctacttg atagaaatgt tggcgtgctt
    22981 cttcttcagg tacaccttga cggatcatct catctaaaag gatgtttgcg atacccacac
    23041 cagcagtacc agcaccaaat gtcaaaatta tttgatcttt caattgttca ccggatatat
    23101 tcaatccgcc taatacacct gctaggacaa caattcctgt accttggata tcgtcgttga
    23161 aagtagtgat ttgatcttcg tatttttcta agatcgctgc agcatttcct cgtccaaaat
    23221 cttcccaatg caataacaat tctgggaata attcggtagc tgattgaacg aattgatcga
    23281 tgaattcata gtaagtttcg ccttctacac gagcatgacg attgcctaag tataagggat
    23341 tattcaataa ttcttcatta ttagtaccag cgtcgatcga tacaggcaaa acttgtgctg
    23401 gattaatacc agcagcagca gtatagacca tcaatttgcc gatagcgatg tcaacaccgt
    23461 tcacacccca gtcgcccata cctaagattc cttctgcatc agtcacaaca atcaaacgaa
    23521 tgtctcgtcc atctgccgcg ttcttcaaac ttgctttgat gttttctggt tcgtcgattg
    23581 aaagaaatgc agcatcttgc ggtttcaaga aaatttcgtt gtattgttcg attgaatccg
    23641 caacgacagg atcataaacg acaggcatga attcaactaa atgttcgccc atcaatttat
    23701 aaaacaatgt ccgattcgta ttgaatagat tcattaagaa gatacgtttt tccaaatctg
    23761 tttgtttgct taagtattga ccataagctt gaacagattg ttgttccagt gtttggacag
    23821 tacttggaag cataccagtg attccatatt ttgcccgttc ttcttttgta aaagctgttc
    23881 ctttatttag aaaaggatta tttaataagt ttaaccctgt aagcatgaat gattcctcct
    23941 aagttttaat acaaacgaag tatagaagtc agatgatgat atagtcaaaa agagcaggta
    24001 tgataaattt tatttatatg taatatagcc aaaagaaatc aaaatagcag tatttgttct
    24061 ttttatatcg acaatccttg cttgaatact atgcgtatct cttatatgct agagaaagaa
    24121 aagtagaaga ataagggata gatggaatgg ataaatagga tttctgagga aaaaagcaca
    24181 tgatagcgtt gataggagtc acctatgtca ggtgataaaa atacataagt agaaaattaa
    24241 gaggaggaag agaaaatgaa agaagttcaa ttgattagaa aaagcgaact atcagaaggc
    24301 ggttgcaatg catgtggcgt agtagaagcg acaagctata cattaaaatt agattccaat
    24361 caagcaataa tctctgaact gacagtaggc ggtcttgtgg acagtctggc gcttgctgaa
    24421 ggttttactg gagaagatat ttatgagatg ttttcagaag tccgtcagtt aaaaaaagga
    24481 gaaaaatgca tagaggttca tcatgagagc ccgaatgtga ggttcaaacg tggtgataat
    24541 gagatgatct tcaagaatca tgtgtctgat cacactgaac tatatgaaat cgtgaatcaa
    24601 atactgtctg ggatttttga attaggacct tatgagttca aggaagaaaa cggtaatcca
    24661 aaattaaatg aagaatggca agaaacgatt gaaacacaaa gaaacaatcc acacttattt
    24721 caatagtctt ccacagtatt tcgtaaaaat gttgatgaaa aagaaacacc gtgaatcaga
    24781 ggtcgtgaaa aacctgccct gcatcaagta ataagaacag ccaaacaaaa atagctcctc
    24841 ctatttttcg tttggttggg cttattaccg cagatgcaag tttttgaaca ccgtttaagg
    24901 aagagactgt gaagtcaacg ttctgacctg agtattagag agacaaatgg caaaatagtt
    24961 cctcatattt tgccattttt tgagctaata ccgagggtca gctgattgaa caccgtttta
    25021 tcgagaggtt gtgaaaaagt cgcttagttt cgagtagtaa gaaaaatttt gtgaaaatgg
    25081 ctttccacat ttttgcataa atttgactta ataccgagaa aatggctttt gaacaccgtt
    25141 tattcaaaaa aagggacttt gacactactt ttgtcaaagt cccatcggtt ttttatctat
    25201 ttttattaca atcatttctt ccagagtagt gacatctgga atggctgaaa tgtaaacaga
    25261 ttatttgcct gtatcaatgt cgaagagtaa tataaaaagt gtaaacgcta tcatattgtt
    25321 catcattcaa attttataga gagaaggcat tgagatggaa aaaacatatc aagcaggtac
    25381 aaatgaagga atagtagatt ttatcaatat ggaagattta gaaatcgcgg cttcacaagt
    25441 gattccagct ggtggttatg gttacatcag cagtggtgct ggcgacttat ttacttatca
    25501 agaaaatgaa cgggcattca atcatcgttt gattattcct catgtattaa gagatgtaga
    25561 attacccgat acaactacac attttgacga agaaatgctg actgcaccaa tcatcatggc
    25621 accagttgct gctcatggat tagctcatgt gaaggcggag aaagcttctg caaaaggtgt
    25681 agcagatttt gggacgatct atacagcaag ttcttacgct tcttgtactt tagaagagat
    25741 aagagaagca ggcggggaga aagcaccgca atggtttcaa ttttatatga gcaaagataa
    25801 tggaatcaat ttggatattc ttgaagtggc caagcgtaat ggagcaaaag caatcgtatt
    25861 gacagcggat gcaacagttg gcggaaaccg tgaaacagac cgcagaaacg ggtttacctt
    25921 cccgctgcca atgccgatcg ttcaggctta tcaatcagga gtaggccaaa cgatggatgc
    25981 tgtatataaa tcttccaaac aaaaacttag tccaaaagat gtagaattta tcgctgctca
    26041 ttctgatttg ccagtctacg tgaaaggtgt tcaatcagaa gaagatgtct atcgatcatt
    26101 agaatctggt gctggtggaa tttgggtatc taaccatggt ggccgtcaat tagatggggg
    26161 gcctgctgcg tttgattcgt tgcaatatgt ggcagaagca gtagataaac gtgtaccaat
    26221 cgtgtttgac agcggtgtac gacgtggaca acatgttttc aaagcaatcg catcaggtgc
    26281 cgatcttgtt gctattggca gacccgttat ttatggattg tctttaggag gaagtacagg
    26341 agtccatcaa gtgtttgatt tctttaaaac agaattggaa atggtcatgc aattagctgg
    26401 aacacaaaca gtagaagata tcaaaaaaat aaaattgcgt gagaatcgtt ttatttaaga
    26461 aataaatgac gaaaaaaata ggagtgcggc agatgatgcc gtactcctat ttttatagtt
    26521 caaggatgtc actaatagaa taatttgaaa cgaaaaaata aaattgaaat attttttcat
    26581 acttaataaa aaaggaagaa tattcatgta aacgatttta ttgttttttt ctcttttata
    26641 caaaaagggt cataatttca agtaagcgga tgaattcatg aggatttttt gcatactgtc
    26701 tctactatac ttaggtcact aagaaaaagg agtgatttat tatgaaaaag aacatgattg
    26761 ggacattatt actttcaaca cttcttctag gcggcttggc aacaccagct tttgctgagg
    26821 gtcaagcgac ttcaaaagga gatattacct ttactgaacc aacaaatacc gttgagcctc
    26881 ttaaccctac tgatccttca aaaccagtag agccagcaga tccggaaaat ccagcaactg
    26941 gccagacagg ttctttaaca ttggatgtag ttcctgaatt gccatttggt acacacgaga
    27001 ttgaaagcgg aacaaaaacg tatcaagtag acgcttcaaa aaacgataca ccttatctcc
    27061 aagtatcaga tcgtcgaggt gtaggtgcag atggccaagc acaagggtgg aacgtgacag
    27121 tttcggtttc agattttgta aacggttcac aagttttgca aggcgctgaa ttagattttg
    27181 gaacatccac tgttaaaagt acgtcagata acgaatccac tggaccaact agtcaaactg
    27241 taactgggtt gagtaaagca agtgcagcga caccaatatt tacagcagca aaagatcaag
    27301 gtctgggaac atggctttct gtttatgatc cagcaaatat cacactgaaa gtgccgaaag
    27361 cagcagctgg aacattcacg gctgatttga cttggaacct cgtggctggc ccagtagcat
    27421 agagtatgaa ataaattcaa caaactgcgg tgaaaatact ataggtgaag gattttttac
    27481 cgcagttgtt gttgaaagga tgtggtggac aatgaatcaa agtaaacgac tgtttgtttc
    27541 gtttttttct attttaagtc tatttttcat ttttccgtca atcagccaag caaaggattc
    27601 agcaggagac tttggaatca aaccggtatt tccagagaac caaatagata aagcaatcgg
    27661 ttattttgat ttattagtgg caccggaaca aaatcagaca ctagaagtaa ttatcagcaa
    27721 ttcttcagat gaagaacgaa catttgaggt ctctgtcaat ccggcggtaa cgagtgatgg
    27781 tggaacgatc gattatagtc aaaaaaaccc aacgttagat gagacattgc cgtttgatgt
    27841 ccgtgacgtt ttgctcattg cgaaaaagga aatcaatgta tcagcacatg cagaaacaac
    27901 tatacctata gaagtgaaaa tcccagcaaa aagctttaag ggacgtgtat tagcgggtat
    27961 tcatgtttca cctaaagaag aagctgaaac agaaaatgct acagaaggag cacaaatcaa
    28021 aaatcgtatt gcttataatc tcgcagtcgt tttacaagaa agtcaagaga cgatagaacc
    28081 ggatctgaaa cttttatcag gagatttgga cgaggtcaac gcaaagccaa ctgttcagct
    28141 tcgtttccaa aatcctcagc ctaggattat cagcaatttg atatttacga gcaagatctt
    28201 ttatgaaaat cagctttata ttgaaaatac gtctaatgaa tttttagttg caccaaattc
    28261 gaattttcac ttgaatcttg atttagctgg tgataaagca aaagccggcg attaccgcgc
    28321 agaaatcata gcaaaatcag gcgacagtaa tgaatggcga tttacacaaa actttacgat
    28381 caaaaaagaa aaagcacaaa aagtaaatga aaattccgtt tttgcagtac aagaacaatc
    28441 tttcccatgg ctttatgcag gattggttgc tgcagttcta gtgttatggt tgattttgct
    28501 gtttttgtgg gtccacaaga aaaagaaaaa aggagaaaca acatgatgag gtgatttcgt
    28561 tgaaaacatc gatcttattg ggagggatta ttgcaagttt gctgttcttc agctggcaag
    28621 agccagtcca agcagatacc aaaagttcag gtacgattac attttatgat ctaagtccag
    28681 ttccgcatcc aagtggttca gtcaatggcg catcaaaaca gcagacacag ctaccgattt
    28741 ataaagaatc taatcaacat ggcgtattcc cggagacgaa tgaagaaaag atccgttttc
    28801 tttatttgat cattggtata gaattatggc ttcttgcgtg gttgttgtta tggagaagaa
    28861 aggaaaagga ggatgaacat gttgctacaa aataaatttt cattttttcg ctccttcttt
    28921 tttacttcgc tttttgtttt aagtatattt atcttttcac cttcggcaga agctgttgga
    28981 gcaacgcctc ctgccatttc ttatgatcca tacacgtatg aaaatatcgt acctccaaat
    29041 ggtggacgta gtgcagtcaa tggcgggaag cttgtccaac taactggggc taaccaattg
    29101 cctaaattga ctgctactta tttgaacgat ggttcaaatg atccttggaa aggtggcacg
    29161 gtccgttttc attgggaaag ccatgtgaaa ctaacaaatg tacttgattt ggtgaatatc
    29221 actgcacaag gatttgcatt tgtggcgatc atcaatttgc cggaacatgt atcaagcagt
    29281 gatgtattaa aagcaattga ctggaacaac gcctacttgt atattgccgg tgcccccatc
    29341 aaggttacta gcggtagttt attatcagca ggaagccata ccttgcgttt tgggatgggg
    29401 tcgtgggata caaatactct attggcagat attattgcta ttattacgcg aggcgaattc
    29461 aacgtggacg atatcccgct tcaatttgat gttacagcta atgtcgcgaa gatgacagaa
    29521 aacggagata aatatgatac gagtccaaac aaaattttga ccaagggtaa attacaacct
    29581 tctatgtcta aaaaggccgt tttttctgtt gatttttatg attcgaataa tattatccaa
    29641 gatcgtatgt tcaattcgat tttagctcca gctgcaggta gattttatcc taaattaact
    29701 ggcggaaact tgaatccagg agcatatgca ttttctgcaa gtgcagagat aaatacgtgg
    29761 aatagttaca tctcaacaag tgattcaaca ggaaaatata atacatttgc tgataccaca
    29821 gaatacgtgg atggaaataa ccagaacctt ccaggctcta ccaatagtcg gacattgacg
    29881 atggggctga ctgaaggacg ttttgatcag ttgccattta gtcgctttga tcgcgtagtc
    29941 aactatttta caggaaaaaa cgttacacaa ggagcaatac tgactcatac tccagcaagc
    30001 acaagtggat tgaatcagac agccaatatc gtgtacagtg ggaaagatgc gcaaggcgga
    30061 ttgctttctc ctgttgcttt aaaggtattg gagcagtaca agctagacgg aacggtttta
    30121 ccaacaaact taacagccga tagtcagtgg ggaaagctcc tttcttctgc atcgtaccaa
    30181 gtcacggcca attggtcagc aactgaacta aaaaagggtt cgatccatta caggctttat
    30241 tcgaaaggaa cccaaaaatt agcgacagga tggacagatc aacttttcca aacgatccaa
    30301 tcaaataacg ggggtgtaaa tacagctact tctacactac ctgcattggc ttcagggcaa
    30361 tattattttg attatcgctt ggtggacgat gtacttacta acatgtatcc gtcttttgcg
    30421 tacaaatggc agtctgaaca agctggaatc accactcttc ctcaaataac agtggctaat
    30481 tttccatctg tgagtgcaga tagtcagcta aaaaacctta gcagacaacc tgagacagga
    30541 gatcccctgt ctgctctatc aggagatacg attcaagaaa atgtgacatt cacgttaaca
    30601 aaatctgggg atgcgataac cgacaaaaaa atcacgatct cacttcctga aaatactact
    30661 tatatcaatg gttccttaaa attaaatggt acaactatcg cagataccgg cattcaacaa
    30721 ggagtttctg tcccagcaga tctattgagc aaaataggag ataccattca tcttacttac
    30781 aactatcaat taaatactgt agatacttct gtacaatccg tcagcatact gacaaaggca
    30841 gctgtacttt ccagcaatat tacattagca gatggtgcta agcttcctaa cccagttgtc
    30901 caaacatctg ctaaaacaat tcttgtcccc aaacaagaat taacattagt taatgtacca
    30961 gatgatttta catttggtaa cgatctcccc aaaccgttga agacaagtta ttatgaagca
    31021 aaaggcgatt tttcttttga tgtgcgggat actcggcttc caagcacgtc tccttggcaa
    31081 ctgacaggga cattgacttc tttatttaag aatgatcaag gtcaagaatt aagcggaaca
    31141 aaattatact tcaatcattc tggatcaaaa caattgattc agcaaggtca aaacacgttg
    31201 atttatgaga gtgatggaac agctaaagga gaggttctcg ttgactttcc cgataccgat
    31261 ggtttactct tagaggtaaa tagcagtacg aatgctcaac ctggcgcaac gtatcaaggc
    31321 atggtcacat gggaactgac agctgggcca accagctaag tgattagaat ttgtatggat
    31381 ctgtgataac tgtcacagat cctctttttc aaggatgaga aggaaacttc tgctgttaaa
    31441 atcagaaatg cttggaggag tggacttgga acttttcagt ttgcttgaaa aaaatgaaca
    31501 acggcaaatc aaacttttcc aacttttatt agaggaaaaa ggagagattt ccgttaataa
    31561 cgtacttacc cgcttatcag ttgatcgggc taccttgaaa gaagatctgt tttatttaca
    31621 agctaacttg gaaaatatca aacaattgga aattgttatc caagaaggga atattttatt
    31681 aatcagacat ggaaatatag cagcagtcga tgtttattat cattgctact tgcgctattc
    31741 tacaaaatat cagatacttc tttatctgtt ggaaaatggc tcatttgatc ggcagaaact
    31801 tgtcatggaa cttaatatca gttcggctac tttgtctcgc agagtgaagg aattaaatga
    31861 ttctttaaat gagtttcatc tgaaaataaa aagcgggcgg ctgaccggtc cagaaagtca
    31921 aatttgttat ttttatttcc aattattttg gtttggacgt ccttatcttg aaaacaaaaa
    31981 agaatacagt gatttatcag gaaacacttt tttagatctg ctgcaaaaag agtttagttt
    32041 tactattaca gaagaaggac gattgaaatt tgaaatatgg ctttccatta tgaagaagcg
    32101 aatgcgctgt acgaaaaaat ccaaaccaga ttatagcaat cttcctgttg gattgtttca
    32161 aacgacacaa tttttattgg acctccatac atttttgacc cgttacttct ttcaatatgc
    32221 ctttccttgg aatcaaaatg aaacgttggt tttttatctt ttcatgatca gtaactttac
    32281 attagataca cataactcgc atgtccagga gtttttgata agcgaaaaat acaaagacga
    32341 cgtagtagct caattgaatc gaacgtttaa acaatcgata gaagaatatt tctcttttta
    32401 tgtttttcca gaagagattt cgcaaaagat tgcgttgaca gtgatgcaaa atcacgctca
    32461 ttttgcctat tttagaggat ggatgaatat ttttggccaa gaaggattaa aacagcggtt
    32521 aactgaagta gaagataaac aattcctggt tttatgtgaa agattggtca gacaaacatt
    32581 tgctattgtt gattttactg aagtagacga ggaaaatgcc cgctttgaat tatttgctcg
    32641 ctatgcatct attttgcgga cgctgatcaa gcagttagaa ttacgtctgc aaattgctta
    32701 tgatcttcct tatgaaaggc taatggcgga tatcgtgaaa gaaatcatcc aggaacaatt
    32761 gctgaatacg atcaaatatg atttagtcga atacgagaaa gaaaagcagt atgatatcat
    32821 tttgactagc caattgaaag agtacccgtc acagaagtcc gctaaagttt ttgtattcac
    32881 tagcaacgaa tataattatg atttccccta tttgaaccaa tttttaaaag aatgttattt
    32941 agaaaaattg aatttaagga tgaataaaac atgaaaatcg tgatcattgg tgcttcccat
    33001 gcaggcatca cagctgccct aaatctaaga aaacttcaac cgaaagcaga agttttactg
    33061 atcgatgaag atcataaaga tggactaggc tatgtttcaa atggaatcaa cctttattta
    33121 aaaggaaaga tacgtagttt agctgaagtt gcccataaca tgcggactct tcaagaaagt
    33181 ggggcaaaac tgatcaccga atggagagta actgaacttg atccagacaa acatcagctc
    33241 atcctcgcat ccaaagaagg aaaaaacgag accataacct atgataaatt aatcgtagca
    33301 acaggttcct ctcctgtcac cttgtataaa caaattgaag ctgaaaatgt ctacacctat
    33361 aaaaatctag tgcaatctaa gcaagtactt gccgctttaa aagaagcaaa agaagtagtg
    33421 atcttcggtg ctggttatat tggattggaa ttagcagatg ctttgagaaa taaaggatac
    33481 attattcatc tagttgatta tatgccgaat gttttatcaa gatatttcga taaggatatg
    33541 atcaacagtt ttcaaaatca gctgcaaact aagcaaatca atttttatcc aaatgaattc
    33601 ttgatcgatt ggaaaaaatc agaagagaaa gtagtatccg tacaacttct atctcaagca
    33661 ataaaggcag atatggtcat tttttctgcc caaactcgtc ctaatacgac attgttaaaa
    33721 gaaaaagtgg ctttgtatga ggatgagact gtgatagtca atgaatatct gcagacaagt
    33781 gatccggaca tctatgcgat tggagatatc gtcccagtca gttttgacaa aaataaacgg
    33841 catctctttt tacctttagt tactcgagct gtacatatgg caagagcagt agcgctaact
    33901 ttgagtggtc agccaaccgc ttacgacctc agacaaaaga taacagcagc agtcattata
    33961 gactactttt taggaactgt agggctgaca gaagatgaag cgccattctt ggaacaaaat
    34021 accggttcgt gttcaggaga atttgatcta tttccacaat acgatgaaga aaacaaaaca
    34081 gtaaatgcaa agctgatcta ccatccggat acattagaaa taattggcgg acagctgata
    34141 agccaagaat tcttattatc agatttgaac ctgcttgcgg atatcgtgaa acacaaaact
    34201 acgattccac agctagcagt tgaggatttt ggatttctgt ctgaacacac ctctcgtttt
    34261 cactacctca atgagttagc ttttaaagta ctagctaaga gagcaaatag caatagagta
    34321 gataaaagac tgtgagaaat atcacggtct tttattgtgt ggggatataa taaatattaa
    34381 tcaatcgaga ataaaaaatt catataatga aatagcggaa gaattttttg agcataatat
    34441 tcgccaaaaa tttatcaagt gataaaattg ttgtataaaa tgattatttc aggaggagga
    34501 gttaaatgtt tttagcatta aatgaaatta tgcattcaaa gttacgttat gcgttagttg
    34561 caggggtgat gtttttgatc gcctacctgg tatttttttt gactgggtta gcttatggct
    34621 tagctcaaga taatcgaaca gcagtcgaca agtgggaggc agattcgatt gtgctttcga
    34681 aagatgcaaa ttcaaatcta gggatgtcca tgattactaa gaagatagca gaagaagtcg
    34741 aaggtgggaa agtggcgtat cttgcccaga cacctggagt cgtgactagt aaagacagta
    34801 cagaagaagg aaaaatcaat gttagcttct tcggtatcga taaaaatcaa ttcatcatgc
    34861 ccaatcttgt tgaaggaaaa gcttttgata acgatgatga ggcagtaggc gatattagtt
    34921 tgaaagaaga atatggtcta gccgtaggag atacagttaa gttatctggt agtgacaaga
    34981 cgtttaaact aactggcttt acggatcatg ccaaattcaa tgtctcacca gttctctata
    35041 caaccatcaa tgcttaccaa gagatccgct tcgaaaaaga agatacaagt gaaaatgcac
    35101 ggattaacgc aatagttgtc agaggtaaaa tcagtaattt acctgaagat ttagaacaga
    35161 tcaaaatttc taaattcatc aatgaattac ctggatataa tgcgcaagta ttgacttttg
    35221 gatttatgat cggatttttg atcgttattg cggctattgt gatcgggatt ttcatttatg
    35281 tactgacgat gcaaaagatt aatatctttg gtgtaatgaa agcacaaggg atcacaggag
    35341 gatttattgc gcgttctgta gtggcacaaa cattcatttt atcatttgtt ggtattcttc
    35401 ttggtctatt aggaacagtg ggaacatccc ttgttctacc tgatgcggtt ccattccaaa
    35461 gcaattggct gttttttggc gtcattagct tgttgatgct ggtagtagct gtgttaggcg
    35521 cactattttc tgttcggaca atcgtaaaaa tcgatccgtt gaaggcaatt ggataagaag
    35581 gaggaagagc atgaaagcaa tagaatttaa agaagtagaa aaaagtttcc aagatggcga
    35641 ccaagtagtt aaagcattga aagaaacaac catgagtatc gataaagggg aatttgttgc
    35701 aatcatcggt ccttctggtt caggtaaaag tacttttttg actttggcag gcggattgca
    35761 gacgcctagc agtggctctg tatttatcaa tgatcaagaa ttcagtaatc aaaaagaaag
    35821 tgaacgcgtt aaactacgtt ttaaagaaat tggctttatt ttgcaagctt ccaatctggt
    35881 tccttttctg acagtaaaaa agcagttatt attagtagat aagatcaaac atgaacatcg
    35941 tcaaaaagaa gcaaaagaat tatttgagca gcttggcgtg gataagttga tcaacaagta
    36001 tccagaagaa ctatctggtg gagaacggca aagggtcgca atcgctcgtg cattgtacaa
    36061 tgatccgtcc attattctag cagatgaacc aactgctagt ttggattcag aaaaggcacg
    36121 agaagtagtc gatatcttgg caaaagaatc aaaagacaaa aataaagcaa cgatcatggt
    36181 tactcacgat acacggctga ttgacaaatg cgatagaata tttatgatgg aagatggtgt
    36241 attgaaagaa aaagaataac caaaaagcag gtggaaaaat ggtccatcga tacaacaaag
    36301 atacacagca aaaaattttg aaagaagcga ctgacttgtt tatgtccaag ggatatctcg
    36361 gcacttcaac aagagagatc gcacaaaaag ttgggatcac ccaacccaat ctctatcatt
    36421 atttcggtga taaagaaaaa ctatatacgg cagttttaga aaaccactta aaagatgttg
    36481 gaaaagcttt gagagaaatc gttcaaacaa gcgaaacggg atttcaagta accttgacaa
    36541 aaatggcgca gtttttgatt gagacacatc tggtcgattt gtttctgatg cttcacgatc
    36601 ttgaaagcaa tctttcaaag gaaacaagag atcatctttt ctttctatgg aagaaaaatt
    36661 atcgtgaacc ttttgaagaa atcttttcag caaaccaatc tgtgctaaga aatgggattt
    36721 caaaagaaat cgcagcaagg cattttttct tagtgttagc accttacatc actcggtcga
    36781 aaagacctgt ggaagaaccg ctaaatgtgg cgcaattgat cgatttatat ttgaatggtg
    36841 tattaggaga agcgtaaagc tgttatatag ggagaaaaat agttaggtga agaagcaaga
    36901 tatgacgaag atcgttatat cttgtttttt ttatataggt agtttttcat aaatacaaat
    36961 ttgttattct ctcatgatta tcagggtata tttttattta ttatgtcggt gttccaggaa
    37021 gtgttttaat ttaataacga agaaattaat tgtttgtaga atgaaggaaa ctatttattg
    37081 ggtagatgaa tcaccacgaa tagtcaaaag gagatttcag gatatgccaa aaatgaaaaa
    37141 aatcatttta gcagtaatgt tattttctac ggttatatct tttacagccc cttttttgcg
    37201 tacttaagct gattttaagt tttgaccctt agtctggatc tacgaggtga gagtcaagaa
    37261 tgaaaaaaat aattggagct tttgtatttg caatcattat cattattatc tgttttcaaa
    37321 tagatgtttt tggtcaaaaa aagatagttg gacaaacggt cagcagtacg aacagtacgg
    37381 ttacaaagac aaaggaatca tttgatgata cagaacaaga gacattaatc aaaatcggaa
    37441 aaaatgaccg tacactatat acagatgact cgctaactac cccacttgca actataaacg
    37501 gcggagagct ggcggagttt ctttctgaaa caaaaaatgc ttatcagatc aagacaaatg
    37561 atggctatac tggatattta gccctcgaag atggaaccaa agtcacaaag aatatacaaa
    37621 caaaaccgga agagctatct gatgcagtga ttgtattaga tcctgggcat ggcggaaatg
    37681 atactggggc attaagcaat gatgaacaaa cagaagaaaa agatataaca ttaagtacag
    37741 ccataaaagt aaaaaaggcg ctagaggatg ctggagcaac ggtttatttg acccatacta
    37801 cagatgaatt agtacagctt ggagatatat gcgactacag tgaagaaaaa aaggcagatg
    37861 tctttatcag tttacacgca gactctacgg aatatgcgaa tgaagcaact ggaatcacga
    37921 catattatta ctatggacaa gaggaaacat tagcacagac aattgctgac tccttcactg
    37981 atctgcctct ggattcaaga ggaatctcca ctgggaacta tcaagttctt cgagaaaatc
    38041 ttcaaccttc tattttaatc gagatgggtt atatgaataa tgatagtgat ttaaaggaat
    38101 tagtaacaga cagttatcag cagcagattg ctgcaagttt gacacaagca ttgaccactt
    38161 attttcagta ataaataagc ccagccaaac aaaaatagct cctcatattt ttcgtttggc
    38221 cgggcttatt atcgcagatg caagcttttg aacaccgttt aaggaagagg ttgtgagcct
    38281 gccgtttaac tccgcgtcac aaggagcaat ttcaaaaaac agcttctcat gtttgatgac
    38341 tattgtgact tgtgaccgag gagttggcat gagaacaccg tttattcgga acaagggact
    38401 gtgacatgac ttttgtcaca gttccattat ttttttagca gcttcaaagc tttttctgta
    38461 ttggcaaaat gaagtttggc atatttttca agcataggca tgccgccttt ctccaatagt
    38521 tttgccgcta cttggtcaga tttcgttcca gctcctgatg gaagggtgat tccagcttca
    38581 gctgatgctt tgtgtaactc ttccaaaaag ctggcacgac tgatgataga agcagcagca
    38641 acagctaaat gatattgttc tcctttagta acgaagtaca gtttttcttg taattgattt
    38701 ttttctaaac gcgcatattt tttaaaattt gcttccggcg taaactgatc gatcaaaatc
    38761 gcttctggtt tttctggctc gatttttttt agcagcaaat ggatcgcttg attgtgcaaa
    38821 gcgactttca tccgaacggc attgtatttt ggttggatct cattgtattt ttctggagat
    38881 aagacaagca gtttataggg gatggttttt tttaagatgt cagcaagctg gatgatttgg
    38941 ctatctttta actcttttga atctctaaca ccaagtttac gtaattctgc aagctgatca
    39001 cgtttcacat aagcagcaca tactgttagc ggaccaaaat agctgccatt tccgacctca
    39061 tcactaccta aaacggataa ttgactgata ttttttggca aagaagaggc tgtttttgct
    39121 ggcttggctt gtttatcctg tgcctccccc catttatcag cttctattgc tgcattcgta
    39181 ccttgaaaca tcacttttcc ggatgtataa gcggtaatgg tcgtcccgtc tttttttgca
    39241 gcaaagctag tataaggaat ctgtttattt aacaaataag agcgatagta tgctttcatt
    39301 tgactaagtt ggtcgtttgt tgctttgata atgacgttgc tcataaaatt ctcctcgttt
    39361 ttatacataa aactataccg caactcacga cttttcgttt tctaagagat tgcgagacat
    39421 agcatttttt taaagtttat catataatag ttaagtatgt gaaaaatatt tgtggagaac
    39481 ggtgaaagaa ccaacttcat ggtacactaa ataaaacttt catcaaatag gaggaaatga
    39541 ttcgtatggc gcacgaaaaa acacgctaca aagcagtgat tgccaaccaa acatatacta
    39601 ttatcggacg ggaaaccaag catcatatgg atatcgtaac gaagctgatc aatgaacagt
    39661 tagcagaatt gaaacaatta tcaccacaaa tggataatga acaagcagca atcttgatgg
    39721 ctgtcaatgc gctttcggat caattgaaga aacaagaaag aatcttggag ctggaagaag
    39781 aaacagcaga attaaagaaa aaaatgatca aatttacaga gcttgaaaat cgtgtgaaac
    39841 gcattgaagc aatcgagaac gaagctcggg aagtattgaa agaaaatggt caagcagatc
    39901 ataccattaa aaatcatgtg gaagcacaac agattttaaa cgagaaacga aaaggacaaa
    39961 ttaaacaaaa atcttctaat taagatcctt ttatcaaaat aagaaaaatt taaaaaagtt
    40021 agaagagaaa ggaacgtagc atgctgagtt tgctgatttt atttttattg ctaattgcgt
    40081 ttttttctgg agcacgtcgc gggtttgctt tgcaaatcat attcgcgatt ggatatgtat
    40141 tgtcatttat tgctgcccag catttttaca aaccattagc aagtcatttg gaattataca
    40201 ttccataccc agctgtcacc ccaacatcaa agttagcatt ttttgatcag gtatttgctt
    40261 ttcacctaga tgaagctttt tatgcaggaa ctgcttttct gattattttg ctaattggct
    40321 ggctgcttac ccgatttgtg ggggtttttg tccatggatt gacgtatgtg ccgatcttga
    40381 gacaggtaga ctggattgca ggaggcatcc tgtcactaat catggcttac gttactatat
    40441 ttttgatttt gcagttactt gcctttgttc cattagatgt ggtccaaaat caattcggcg
    40501 agcatagttt cgctcgtttt atcgttgaga gaacgccatt tcttaccaac aagatgtatg
    40561 agctttggta acgaatattt tgaattaagg aaaatagtgc tggaaaatat ttcgtttttt
    40621 gtacagagta gtttatttaa gaaggctgcg tagcgtatgt ccggcacagc tcttttttca
    40681 tagtgaaaga taaggtgata aaatgaataa ccgaatcctt gaaacattgg aatttgaaaa
    40741 agtcaaacag atggtcagac aatttgtagt gactgcacaa ggaaaagaag aactggcaga
    40801 attggtacca gtgagtgaga aacaaacgat cacaaactgg cttcaagaaa ctgaggatgg
    40861 attgaaagtg caacgtctgc gaggcgggat ccctatacct aaacttgaaa atatccgtcc
    40921 ccatatgaaa cggatcgaga tcggagcaga cttgaatgga gtggagcttg cacaagtttc
    40981 cagagtattg tctacgacaa gcgaattgaa tcgtttcatt gatgatcttt ctgacagtga
    41041 aatcgaattt gcacgtttgt atatgtgggc agatcagtta gtcacgatcc ctgttttgag
    41101 ccgccgttta aaggaagcaa tcgatgaaga cggacgcgtg actgatgacg cttctcctga
    41161 gttaaagagc ataagacaga acattcggcg aagtgaacaa gctgttcgtg aacagttaga
    41221 tgggatcgtc cgtgggaaaa atgcaaagta tttaagtgat gcgatcatca ccatgcgaaa
    41281 tgaccgctac gttatcccag tcaaacaaga ataccgcggt gtatttggcg gtgtagtcca
    41341 cgatcaaagt gcttcaggac agactttatt tattgaacca aaacaagtgg tggatttgaa
    41401 taatcgtttg cgtcaatacc aaatcgctga acgaaatgag attcaacgta ttttaagtga
    41461 actttctgct gaacttgttc cccatcgtca agaaatcatc cacaatgctt atgtgattgg
    41521 taaaatggat ctgatgaatg caaaagcacg atttggtaaa gaagtaaaag ccatcgtgcc
    41581 gggaatcagt gaagacaatc atgtcgtctt gaaacaagca agacatccac tgatcgatca
    41641 ggaaaaagta gtttctaatg acatcacaat cggaaaagac tatcaagcca tcgtcattac
    41701 aggacctaac acaggtggga aaacgatcac gttgaagact ttaggtctgt tacaactgat
    41761 ggggcaagca ggattaccga ttcctgcagg tgaagaaagt caaatcggta tttttgagga
    41821 agtatttgcg gatataggag acgaacagtc gattgagcaa agtctatcga ccttttcttc
    41881 tcatatgacg aacactgtag atattttatc aaaagtcaat gaaaaaagtc tggtattatt
    41941 tgacgagctc ggtgcaggaa cagatccgca agaaggtgct gctctagcaa tcgcaatctt
    42001 agatgatctt ggtaaaaagt ctgcttatgt gatggcaaca acgcattatc ctgaattgaa
    42061 agtttatgga tacaatcggg caaatacgat taatgccagc atggagttcg atgtggatac
    42121 actaagtcca acgtatcgtt tgctgattgg cgttcctgga cgaagcaatg cgtttgaaat
    42181 ctctagccga ttaggtcttg atacagaagt tattgatgaa gcgaagcagt tgatgaatga
    42241 tgagagccaa gatttaaacg aaatgatcac agatttagag aatcgccgga aaatggcaga
    42301 gaccgaatat ctggaaatgc gtcattttgt ttctgaggca caagaacttc acgatgattt
    42361 gaaagaagct tacagctatt tctttgaaga acgtgaaaaa gaaatggaaa aagcaaagaa
    42421 aaaagcaaac gaagtcgtgt cagaggcgga agaaaaagca gaaaaaatca ttgctgatat
    42481 tcgtaaaatg caacagcaga ttgggcaagg aaatgtgaaa gagcatcagt tgatcgatgc
    42541 aaagacccaa ttagcaaatc tacatcaaga agaaactttg aagaaaaata aagtattgaa
    42601 gaaggcgaaa gaacaaaaaa cgttgaaacc gggagacgaa gtgttggtta cgacttacgg
    42661 ccaaagaggg acgcttttac gtaaaaacgg gaatcagtgg caagtagaaa tcggtatatt
    42721 aaaaatgaat gtgtccgaag acgagctgac gcctgttgct cctcaaaaag agccgacaca
    42781 acgagttatc catgctgtac gatctgaatc tagtagtcac gtgccgaatc aattggacct
    42841 tcgaggaaaa cgatacgaag aagcgctaag tgaggtagat caatatttgg attctgccat
    42901 tctagctggt tatcctcaag tgactattgt ccacggaaaa ggaacaggcg cacttcgcaa
    42961 gggaattact gattatctta aaaaccatcg gagcgtcaaa agctttgagt ttgcaccggc
    43021 aaaccaaggc ggaaatggtg cgacaattgt taaatttaag taaagcttac taaaggtaag
    43081 cagatggttc gctatccaag tatagaaatg ctatactaat catagatttt aaaaatggag
    43141 gtctttgata tgtcacaagt aattacagat aagacattta atgaagaaac agataaagga
    43201 cttgtattga ttgatttttg ggcaacttgg tgtggtccat gtcgtatgca agcaccgatt
    43261 ttggatcagt tggaacaaga atatgatgaa gaagaattca gaattgctaa aatggatgtg
    43321 gatgaaaatc cagaaactcc tcaacaattc ggtatcatga gcattccaac attaatgttg
    43381 aaaaaagatg gtcaagtagt agaaaaagct gttggtgttc attcaaaaga acaactacgt
    43441 caaatgatcg atcaatattt ataaaaactt acagcaaaaa taagctgagg gtgggactga
    43501 atccagttcc gtcctcggtt tttttgcggt tgagttaagg ttattcaaat taatattttt
    43561 tgagtataat tacgttgtca ggctggattg tttttttgac agacatgcta taataacttt
    43621 aattgaatat gaaggggagt accagatgaa cgaacgaatc aaaaacaaat tagctttact
    43681 tcctgatcag cccggctgtt acttgatgaa agataaaaat ggaacgatca tttatgtcgg
    43741 caaagccaaa atattaaaaa atcgtgtccg ctcatatttt actggcagcc ataatacgaa
    43801 aacggaacgg cttgttagtg aaatcgaaga ctttgaatac atcgttacag aatcgaatat
    43861 cgaagcattg ctcttagaga tcaatctgat aaagaaaaat gatcctaaat acaacattat
    43921 gttaaaggat gataaaacct atcctttcct taagataacg aatgaaaaat atccccgttt
    43981 ggtgattact cgtaaagtac taaaagacaa agcactgtat tttggaccat atcccgatgt
    44041 cggtgcggcg aatgagacaa agaagatcct cgatcgatta tttcctctga gaaaatgcaa
    44101 acctagtcag acgaaggagc cttgtcttta ctatcatttg ggacaatgtc tgtgtcctta
    44161 ttatttcgac gtagatccga aagtctatac gaaaatcgtt gatgaagtga aaaagttttt
    44221 aaacggagga cacgaaaaaa tcgagtcaga gatccatcag aaaatggaaa aagctgctga
    44281 aaacatggag tttgaaaaag ctgcagaata ccgagaccag atccgtgcca ttgagacaat
    44341 catgactcgc caaaaaatga caaatactga tttactggat cgagatgtat ttggttatgc
    44401 gattgacaaa ggatggatgt gtgtccaagt gtttttcgta agacaaggaa agctaattga
    44461 acgagatgtt tcaatgtttc ctttctataa cgaagcagaa gaagatttct tgacttacct
    44521 cggtcagttt tatcaggaaa atgagcattt cattcctaaa gaagtcttga ttcctgatac
    44581 gatcgacaag cccagtgtag aagctttgtt agctacgaaa gtgctgcaac caaaacgagg
    44641 agaaaagaaa aaattagttg aattggcgaa taagaatgcc tcagttgctt tgaatgaacg
    44701 gtttgatctg attgccagaa aacaggaacg gacgatcgga gcagttgaac gtttaggaaa
    44761 cgcgatgaat atcccgaccc caatacgtat cgagtctttt gataactcta atatcatggg
    44821 gacgaatcct gtggctgcga tggtcgtatt cattgatgga aaaccggcaa gaaaagaata
    44881 tcggaaatat aaaataaaaa cagtcaacgg accggatgat tatgcatcaa tgagagaagt
    44941 catctatcgc agatattcac gagtgattcg cgaagggttg cctttacctg atttgatctt
    45001 gatcgatgga ggaaaaggac aagtagatgt ggcaaaagat gtcttagaaa atcaattagg
    45061 aatcgatatt cctattgctg gcatggcaaa aaacgataaa cataaaacaa atgagttgct
    45121 attcggtata gatttggctg tagtaccgct tgagcgaaat tcaccagagt ttttcttact
    45181 ccagcgaatc caagatgaag tccatcgatt cgcaatcact ttccatcggc agctacgcag
    45241 taaaaacagt tttgcttccc gattagatga aattgaaggg ttaggaccaa aacgaaaaaa
    45301 aatgctgctt aaagagttca aatcgttgaa aaatatcaca gcagccacga cagaagaatt
    45361 acaagaaatc ggactgccga aaaatgtcgc acaaaacgta tttgataaat tacatcagga
    45421 atgaggaaag ggcactttac aaagaaagta aagtgtccta tcattttatg tacaacaaaa
    45481 agagcgttta cgttttgttg gtaaataata aatcgcttac gtctggtgtc taaggatata
    45541 tgtgatttct tgaagaagga gtgaagaaat gttagaagtc aaggatcttg ttaaaacttt
    45601 tgggaactac acagctgtcg atcatgtctc tttccaaatc cccgatggaa aaatcatggg
    45661 gctaattggc caaaacgggg ctgggaagac aacgactttt cgtttgatct tggatttttt
    45721 gacacaagac caaggagaag tgttatggaa tggccatcat cttggggaga aagattatga
    45781 tgtcatcggt tatcttccgg aggaacgggg actttatccg aaagtaacga ttcaagacca
    45841 actgctttat tttgcagaac ttagagggaa atcaagaaaa gagattgaac caaaaatcga
    45901 tttttggatg gaaaaatttc aggtaaaagg gaaaaagacg gataaagtaa aatctttgtc
    45961 taaaggaaat cagcaaaaag tccagctgat cgccacgtta atccatgaac ctaaattgat
    46021 cattttggat gagccattca gcgggttaga tccggtaaat gctgaattgc taaaagatgg
    46081 aatattggaa ttgaaaaaac atggttcatg tgtcattttt tctagccaca atatggataa
    46141 tgtagaaaaa atctgcgatc atttgatcat gttgcgaaac ggaaaaatgg ttttgaatgg
    46201 aaaagtacat gagattcgtg aatcatttgg ccgtacgaag ttattcttgg aatctggttt
    46261 aagccaacag gaagtagaag aaatcgaagg cgtgaaaaaa gtgatccttc atgaagacaa
    46321 tacgttagag attaccttag aagatcctga agctgggaaa gaaatcttta ctcgtgcgac
    46381 tcagttcggc tacattccta tgtttaacca gcaaccgcca actttggaag agattttcaa
    46441 attgaaagca ggtgaaatcg atgcgtaagt tttggattat taccaaagat gtctatttaa
    46501 aaaatgttaa gtcgatttct ttcttgatca tgatattagt cccttttatc atgctgggta
    46561 tcatttatgt agcaggaaac tttgctcaac aaaatagtga tgtcaataaa atcggcgtat
    46621 tggctgataa tgagcaaatc agtcagcaaa tgagccaagt caaaacagat gattttgagt
    46681 tcaaagcagt tgattctgaa gaaaaagcac aaaaagagct ttcggaagaa aaaatcgatg
    46741 cgtatttagt agtctcaact gagaatgata agataaatgg gatgctttat agcgaaaatt
    46801 cattaggaca aagtacacaa ctactgatac aacaacaact gactggcttg caatcgatgc
    46861 ttcgagcaag tcaattaggc atttcaccag aagaagtagc tagcttgagc caacaagcaa
    46921 gtttgactcg acaaaaagtc aattttgatt caaaaggaaa aatgacagtt ggagaagata
    46981 actcgacagt ccaatatgtc gtaagttatg tagcaacgat tgtcttgttc attattattt
    47041 tgacgtatgc gcagatcatt gcacaagaga tcgcttctga aaaaggcacg cggatcatgg
    47101 aagtgatcct gtccagtacg actgcacaaa agcattttta cggaaaacta acaggtgttt
    47161 tacttgttgc attaacgcaa atggcattat acggtattat ttttggtata ggatacagtc
    47221 aattcaaaga tatggaaatg gtcaaaaata tattagacgg tatctcattg gataacttga
    47281 ttggaccatt cttgtggtat tctcttctat tcatgatctt tggcattttg attttttctg
    47341 ttttagcagc tttatgtggc tctttggtca acaaagcaga agatacagca aaagcaattt
    47401 tgccagtgac ttatctatct ctaggcggat atatgcttgg attgatacta ggagcttcag
    47461 atccaaacaa tatcgttatt cggatcactt cgtatattcc attcttatct tcatatatta
    47521 tgccggttcg cttagcaaat gagacagtcg gtatgggtgg agcattgatt tccttgttgg
    47581 tacttgtagc cgtaacattc ttattgatga tcttgtctgc aaacatgtac aaatcgaatg
    47641 tactcgtgta tagcgaaggc ggattatgga gttcattgaa acaatcgatt tcaattatga
    47701 gaaatgaacg aaaaaaagca taaaatatag aaaaatatag aaggaagctg gacatttatt
    47761 gttcccagct tcttttttgt atagacctat ttctattttt ttattatatt ggatatatat
    47821 attcattgaa aatagagcat aacaacttta taatgttgag tataccaatt tttggaggcg
    47881 ttttaatgga ccgctattta gatttacttt cagagaagtt ccctacaacg gaagatgtca
    47941 tcacggaaat catcaatctc gaagcaattt tgcagcttcc aaaaggaaca gagttatttt
    48001 tgagcgatat acatggcgaa tttcctgctt ttgatcatat tctgcgtatc ggttcaggaa
    48061 atcttaaaga aaagatcaaa gaccttttct ctgaacaaat gacggaaacg gagatcagcc
    48121 aattcactat ttttacggct tatccagaat atgtgttgac gactgattgg tacaaaaaac
    48181 aagataaatc ccagctgatc catcgtttga tcgatctttt acggtttacg acagtcaaat
    48241 acactcgatc aaaagttcga aaaggattgc cgaaagaata tagctatatc attgaggaac
    48301 tcttgtatat cgatgatcgt atcaacggga aaaaagacta tgtaaaaaaa atcattgaac
    48361 aacttgtctt gatgaaggaa gaagaaaaat ttttaacaaa acttgcgcag acgatccaaa
    48421 aatctgtcat cgatcatttg catatcgtgg gtgatatttt tgatcgagga actcaagcag
    48481 ccaaagtaat ggatcgaatc atggattttt cctctgtaga tatccagtgg gggaatcatg
    48541 atattttgtg gattggtgcg tattgcggct ctgaggcatg tttattgacg cttttacgga
    48601 ttgccgcacg ctacaactat ttatttgaat tagagaaaga atatggatta aatttacgtc
    48661 cattattttc ttttgcccat caaacctatc agaagaatcc agtatttacc cctaaaaaca
    48721 ggaaagatct atctgaaaga gagcaagaag aattagaaaa gatccatcaa gcactttcta
    48781 tcctccaatt caaatcagaa catcagttgt tgaatcgacg acctgaattt aaaatggacg
    48841 atcgtaaatt gttggaaaaa atcaactatg aggaatcaac gatcgtttta gaaggtcagc
    48901 tctatgagtt gaaagggact tgttttcaaa cgatccagcc agatgatcct aaaaaattct
    48961 tggaagagga acaaaaagtg atcgatagtt tgatgtattc attccagcac tcgttaagaa
    49021 tgcaaaaaca catgacgttt ttgatcgaaa aagggggaat gtatctcacg aacaatcagc
    49081 atgtactgtt ccatggctgt atacctgtag atgaaaaggg gcagctctta gcatttgaat
    49141 tagaccaatc ttatcgcgga aaagaactgc tgggattttt tgaaaaacag ataactgaaa
    49201 gcgcaaaaga tttgactgca aatgaagatt tggcgaccga tttgatttgg tatgcgtgga
    49261 gcgggccatt ttcgccttta ttcggcaaga gtaaaatggc aacttttgag cgctattttc
    49321 tcacagagcc tcatacgcac gtcgaaaaaa gcaatcccta ttatcacttg cgagatgaag
    49381 agtggttcag tgaaaaaatt ttggcagaat tcgatgcaaa agaagaaggt tcagcaatca
    49441 tcaatggaca cacgccagta aaagtaaaaa aaggagagtc accgatcaaa gcaaacggaa
    49501 aagcatttgt tattgacgga ggtctatcca aagcttatca aaaaacaacc gggattgctg
    49561 gctactcatt actatgcaat tcttacggtt tccaaatcgt gacacattat ccgttcttgc
    49621 ctattgaaca acaatttgca aaaaaatctg atcaaacgaa tgtaaaaaaa gtgatcgagc
    49681 agcagctccc acgcaaactt aatcggaata cgacaaaagg aatggaatta cagcaacaga
    49741 ttactcaact ccaaaggctg ttggattatc gaaaggacga ttgagaaaaa tgctagccaa
    49801 cattgctcaa tagactaaaa agcgactgca acaaaaggcg tgtcgcagtc tccttcggaa
    49861 ttagctcaaa aaacggtaaa atattagaag ctatttttct gtttatttct ctaatactca
    49921 ggtcagggcg ctgatttcac gacctcttcc ttaaacggtg ttctcctgcc aactcctcgg
    49981 tcacaagtca caatatccaa caaacatgag aagctgtttt ttgaaattgc tccttgtgac
    50041 tcagagttga acggcaggct cacgacctaa tcagaaaaac gattaaaatt cattcacaaa
    50101 gaaatcgaat aaacgctgtt cagatgaatc tacacgatga gaaagttccg gatgccattg
    50161 gacaccaagg attttgtgca tattatcttt actttggact gcttcaatga gtccatcgtt
    50221 ggaaaaggcg atggctttta acaaaggaga aagatctttg actgcctgat gatgatagga
    50281 attcacaaag tatgaatcag ggagaaggtc acttaataaa ctgtccgaaa cgattttgac
    50341 ttcgtgagtt gcaaactgcg gggcagtggg ctgttgttcg tgttttacgg accattttgg
    50401 atataatgaa agatcttgat aaagtgttcc ctccaacacg acattcaata gttgaagtcc
    50461 tcggcagact gcaaaaatcg gttttctttg tttcaatgct tccaagatca atgcctgttc
    50521 gaattggtct cgttgaatat ttgtttccgt cagttttgga tgagggtctt ccatgtaaag
    50581 ttgcggacta acatcctgac cgcctgcaag aatgagtttg tcgattttct caattagttg
    50641 aggcgctgaa tctggagaca tgactggcag aataagaggt aatccttgag catctaaaac
    50701 tgcatccaca aatccctgcg gtgtatagct tacttgattt ccttggaaag tatctgtcgc
    50761 tcgaatcagt tgattcccgg caatgccgat gattggtttc atttttattc cccctaaagt
    50821 agactaattg taacaaggat ttaaaaaaat ttaaactatg taagacttgc ccctatactt
    50881 atctgttctt gctgtgttac tatctgtaaa gagaattttc gtgtgaaatt catgacgata
    50941 gttgaaaata ttgcttaatt tgttataata aaaagtaagc agaaataaaa aggttgggcg
    51001 taagcttcaa ggatctagtt cttcaagggg tgagaaggac attttattga aggggcctgc
    51061 ctatactaag ttatctttag aggtacatac tttcaatgaa aaaagaaagc atgtacctct
    51121 tttttaaatc gaaaggaagt gaagcaagtg ttagaagctt tggaacaaat ccgaaaagca
    51181 gaagaagaaa atgagaagcg tgctcgaacc ctacggcagc agttgaagac ctatgcagaa
    51241 gaaaaagagc aagaattgga gataatccaa acgaacagtc ggcaacagct gaaacagttg
    51301 gtagaagaaa aagaacaatt cgaaaagcaa gaattagaaa aagaaaaaat gaaattgaaa
    51361 gcagaagcag acaaggtgca agcaactttg aaagaccaat atcaaaagca tcagagtcaa
    51421 gcaatcggtg caatcattga aagggtgaaa gaaacttatg gccgtcacta agatggaaaa
    51481 agtgaccctc atttcagata aaagaaatca ggagaggatt ttacaagcag tacaaggaat
    51541 ccaaaatgtt gaaatccggg atctgtatca aaatagaaca aacaaccagt gggtagaaaa
    51601 atattttcca gataccacga ttattgataa agaagcaaaa ttaagcgctt taggcaatcg
    51661 gctgaaagac atccaagaag ctatccaatt catacaacac cacggcgata gccgtcaaaa
    51721 gaaactccat ttgaaacgtc aagaactttc cttacaagac ttggaagcaa attattccga
    51781 agaaaatttc atgaataaat tagaagaagt ccttgattta aaagaaaagt gggaacagct
    51841 aactgaaaaa cgtgatcgtt tagaagaaga ggaagaatgg cttcttcatt ggcaacagct
    51901 ggatattgct ccaagtatgt atgcaagtaa gacgaccatt tttgagatgg ggactgtgag
    51961 tgcagcaaat tttgaaagtt tcaaggaaga actaagtaag cttgatgacg tttatatgga
    52021 agaaatagat tatacgccaa aacaagttta tctttcgtat gttgctttaa aaaaatcagt
    52081 tgctgctata gaagaaattg ctgggaaata cgggttcaat aaagaaacgt atccttatga
    52141 acaaaatcct aaagaaaaat tgcaagaaac caaacagcaa ttatccattg ttcacgagca
    52201 gcaaaaaaag ataacgacag cgttaggtca gtgcagcggc tatatccaag aatttgaatg
    52261 ggtagaagaa gtcacacttg ccgttgcaga acgggaaaaa gtaaaagaac ggtttatcca
    52321 tgccacttat ctgatcgttt tgcaaggttg ggtagatgca gaagaaaaac agaatttgat
    52381 gcatgtgtta aacgaaactg tatcagaaga agatatatac gttagtttcg aaacaccaaa
    52441 ctcagaagag attcagcagg aagtccctac taaattgaaa aaccatccgc ttatcgaacc
    52501 ttttgaattg ctgactgaaa tgtacagtct gccaaaatat gaagaagtag atccaacgcc
    52561 ttggatgaca ccattttatc ttgtcttctt cgggatgatg gtcgcagatg ttggttacgg
    52621 attgctgatg ctcattggga caatactagc tcaaaaacta tttgttttac cccgcgggat
    52681 gaaacgtttc gtaaaattct ttgagattct ctcggtacca tcgatcatct ggggattgat
    52741 ctacagttca tttttcggac aggcattacc aaaagaacta tttggtatcc gcttgccttt
    52801 cccaatccta tctacgacgg atgacgtcaa tacgattttg attttatccg tgattttcgg
    52861 tctgatacag atcttggttg gattattcgt ggcagcaaag gaaaatatca ggaggaaaga
    52921 ttacttgagt gctgtcagtg atggttttgc ctggcaaggg atcctgattg ggatcgttat
    52981 tgcattgatt ggtgtcatgt tgataaaaaa tacagcattt gtttatcttg gcgcggggct
    53041 atcgatcatt gctgctttat gtatcttaat cgtgccgatt atccaatcgc cgtctaaagt
    53101 caagggtgct gccaaaggag cgtataatct ttacggattg actggttata tcggtgattt
    53161 agtcagttat acacgtttga tggcactagg tatttcaggc ggaagtattg gcgcggcatt
    53221 caatatgcta gttgctttca tgccgccagc cgctcgattc agtgtaggga tccttttgat
    53281 catcgcttta cacgcactga atatgttttt gacactgtta agtgcctatg tccatggtgc
    53341 acgattgcag tatgtcgaat tttttggaaa attttataca ggaggcggac gtgcctttga
    53401 cccgctgaaa acggcggaaa aatacgtcaa catcaatcat aagaaaaaaa acaataaata
    53461 attggaggat ttttatacaa tgatggatta cttaattagt caaaatggtg gaatggtatt
    53521 tgcagtatta gcgatggcaa cagcgacgat tttttcaggg attggttcag ctaaaggtgt
    53581 tggaatgaca ggtgaggcag cagcagcgtt aacaacaagt caacccgaaa aattcggaca
    53641 ggctttgatt ctgcaattgc ttccaggtac gcaagggttg tatggattcg ttatcgcctt
    53701 tttgattttt atcaacttag gaaatgatat gtcagttgta caaggattga actttctagg
    53761 cgcttctctg ccgattgctt ttacaggttt gttttcaggt atcgcccaag ggaaagttgc
    53821 agcagcaggt atccaaattt tagcgaaaaa acctgaacat gctacaaaag gaatcatttt
    53881 tgctgcgatg gttgaaacat atgcgatttt aggtttcgtt atttccttcc tattagtatt
    53941 gaatgcctaa gcataaagga ggaaaagcag atgaacgcca ttgaaaaaat catctctcag
    54001 atgaatgaag cagcagagca agaaagagcg gcgttagagc aagaagagcg aatgaagatc
    54061 gatcaaaact ttgaacaaaa acgtacgcaa atcgaaacag aacatcaaaa acaaaaagaa
    54121 aaacaaatcg aattacttga aaaaaaatac cgtcagctta ggaatcgcca acaagtagaa
    54181 gtacgacaag aaaatttgaa tgcgaagcag gaatttttac gacgattgtt tgcagatgca
    54241 atagctgaaa tggagaattg ggatgaatct gaacaaatcc agtttatcaa aaattcattg
    54301 tattcattac ctttgacagg caaagtaaca ttcattgctg gagaaaaatc agcagcttat
    54361 ctttctcaga cattgctgga tgaatggaac aatgaacttc cctttatgat ggttttaagt
    54421 gatgaaactg ttgctgatca agcgggtttt ctgataaacg atcaaggagt tcagtataat
    54481 tttcttttca gcagccttgt acaagatatc caaggaacga tgagttttga gattgccaat
    54541 caattattcg aataaggagg gatcagtgta tggaatacca cgaactaaat cccttgattc
    54601 gcggaagaga gcttgaactt ttgtccaatg agacatttga acggatgatt caaacaaatt
    54661 ctgtcgaagc acttggtgaa atattgaaat ccacgattta cagtccatat atttatgacg
    54721 gatatgaata tgacttcgaa cagaatcttt taaaggagca gagccgtcta tttcgctggt
    54781 taaaggaatc agcaccggag cctgaaatcg tttggatcta tacgatgcgc tatactttcc
    54841 ataatctgaa ggttttgaca aaagccgaga tgacaaatca aaatctggac catttgtata
    54901 tcgacgatgg attttattca ttagaaacct tgaaggatgc cattcatacg caagtttcaa
    54961 atgaactccc tgaaagcatt atggacagta tacgagaagt acgtgattat tttgaagagt
    55021 ctaccattct tcagggaatt gacgtgattt atgatcgaca gtttttgaca gagcagcgac
    55081 ggcttgccga taagctagga tatcaagaat tgctgacaga agtcattgct tttattgact
    55141 tgaccaatat cacaacgatg gctcgaggaa tattgcagaa aagaacatat gggttcatga
    55201 cgacggtact ttccagctcg ggaagtatcg aaaaagaagt atttttgaac tttgtagata
    55261 aagatatgga agattacacg aattttctat tagagacaga ttatgctgat tttctgcgcc
    55321 ctgtcatccg tgagggaaat cttgatctcg taaagcttga acagttgaaa gatgattatc
    55381 taagttcatt gtatcaagaa gcacaaaccc aggctttcgg accactgcca ctactagcct
    55441 ttttgaacgc aaaagaggta gaaagcaaaa accttcgttt actggttatc ggcaaaagaa
    55501 gccatttcga accagaaaca atcagaaagc gggtgagaca agtctatgac gcataagatc
    55561 ggtgtagttg gcgacaaaga ttctgttttg ccattcaaat tgtttggctt tgatgttcgt
    55621 tatggtacaa ccaagcaaac cgttcgtcag gcaattgaag aaatggcaaa gaatgagtat
    55681 ggcgtgattt atgtcacaga gcaatgtgca gcattgagcc cagaaacgat cgaacgttac
    55741 aaggaacaaa tgatacctgc tatcgtattg attcccaatc atcaaggatc attagggata
    55801 gggctggaag aaattcaaaa aaacgtagaa aaagcagtag gtcaaaatat cttatagtat
    55861 gaaaaggaga tagaaatttt gcaaattgga aaaatcataa aagtctccgg acctcttgta
    55921 atggctgaga acatgtctga tgccagtatc caagacatgt gtctagtggg agatctagga
    55981 gttatcggag aaattatcga gatgcgtggc gatgtggcgt ctattcaagt atatgaagag
    56041 acttctggaa ttggtccagg cgaaccggtt cgctctactg gtgaagcttt atctgttgaa
    56101 ttaggaccag ggatcatttc acaaatgttt gacggaatcc aacggccatt agataccttt
    56161 atggaaatca cacaaagtaa tttcttaggg cgcggagttc aattgcccgc attggaccat
    56221 gagaaaaaat ggtggttcga accaacagta gaagccggag aaacggtgag tgctggagat
    56281 gttatcggga tcgtagaaga aacaaaagtt ataaaacata aaatcatggt gccaaatggg
    56341 ataaaaggaa cgatcaaaac aatcgaaaaa ggttcattca ctattgatga aacagtatgt
    56401 gtcattgaaa ccgaaaatgg tgacaaaaat ttgacgatgc ttcaaaaatg gccagtaaga
    56461 cgtagtcggc caatcaaaga aaaattaaac ccggatgcac ccatgatcac tggacagcga
    56521 gtgattgata cattcttccc agtgacaaaa ggaggagcag cagctgtacc tggtcctttt
    56581 ggtgcaggga aaacagtcgt tcagcatcaa attgcaaaat gggccgatgt ggacatggtt
    56641 gtctatgtgg gatgtggcga gcgtggaaat gagatgacgg atgttttaaa tgaattccct
    56701 gaattgattg accctaatac aggagaatcg ttgatggaac gtacggtatt gattgctaat
    56761 acatcaaaca tgccagtagc agctcgagaa gcttctatct atacgggaat cacaattgcg
    56821 gaatatttcc gtgacatggg ttatgacgtt gctatcatgg cagactccac ttcacgatgg
    56881 gcagaagcac ttcgtgagat gagcggacgt ttggaagaaa tgcctggtga tgaaggttat
    56941 ccagcttatc ttggttcacg gcttgcggaa tactatgaac gatctggaag agtcattgca
    57001 ttaggatcag aaggtcgcga aggaagtata accgcaatca gtgctgtatc cccgtctgga
    57061 ggggatattt cggaaccagt cacacaaaat acattgcggg tcgtaaaagt attctggggt
    57121 cttgattcca gtttagccca aaaaagacat tttccttcga tcgattggat acaaagctat
    57181 tctctttatt caacagaagt agggaagtat atggatcata tccttcaagc tgactgggca
    57241 tccatggtca ccgagggcat gcgtattttg caggaagaac agcagctgaa tgaaatcgtg
    57301 cgtttggtag ggattgattc cctttcagat aatgaccgtc tgacattaga agtggcaaaa
    57361 tccattcgtg aagattattt gcagcaaaat gcttttgatg atgtcgatac attcacttca
    57421 agagagaaac aattcaaaat gttgaagatg atcttgacct ttggtgaaga aggacgccgt
    57481 gcgttgtcgt taggtgctta tttaagtgag atcatggacg gtaccgtatc gattcgtgaa
    57541 aggatcggac gaagcaaata tatcccggaa acagaattag aaaaactaga tcaaattatt
    57601 ggtgaaatca agcaaacgat gcaaacgatc gtttcagaag gaggcatgag caatgattaa
    57661 agaatatcgt acgatcggtg aagtcgtcgg tccattgatg gcggttgaaa aagttgctgg
    57721 tgtcaaatat gaagaattaa tcgaagtccg tatgcaaaat ggcgagattc gtcgtggaca
    57781 agtattggaa gtccaagaag ataaagcaat ggtccaaata ttcgaaggaa caagtggtat
    57841 caatttacgt gactcttctg tacgattttt aggccatcct ttagaactag gtgtatcgga
    57901 agacatgatc ggtcgagtat tcgatggttt gggacgaccg aaagataacg gaccagagat
    57961 cctgcctgaa aagcatttgg atattaacgg agaagtaatc aatccagtag ctcgggatta
    58021 tccagatgag tttatccaaa caggtatctc tgcaatcgat catttgaata cattagttcg
    58081 tgggcaaaaa ttaccagtat tttctggctc tggtcttcct cataaagaat tagctgctca
    58141 gatcgcgcga caagcaacgg tactcgattc atcagatgat ttcgccgtag tctttgctgc
    58201 tattggaatc acttttgaag aagctgaatt tttcatggaa gattttcgtc aaacgggcgc
    58261 aatcgaccgt tctgtcatgt ttatgaattt agcaaacgac cctgcaatcg aacgtatcgc
    58321 tactcctcgt atggctttga ctgctgcaga atatcttgct tatgaaaagg gaatgcatgt
    58381 tttggttatc atgacagaca tgaccaacta tgcagaggca ttgcgagaga tttctgcagc
    58441 acggcgagaa gttccaggaa gaagaggata tcctgggtat ctttacacga acttagctac
    58501 tttattcgaa cgagcaggaa gaatccgcgg actaaaagga tcggttactc aaattccgat
    58561 tctaacaatg ccagaagacg ataaaactca tccaatccct gacttgactg gttatattac
    58621 agaaggacag atcatcttga ctagagagct ttacaagagt gggattcagc caccaattga
    58681 tgtactcccg tctctttcgc ggttaaaaga taagggaact ggacccggaa agacaagaga
    58741 agaccatgca gctacgatga atcagctttt tgcagcctat gcacaaggaa aacaggcaaa
    58801 agaattagcc gtagttttag gtgaatctgc tttatctgat gtagacaaga tctatgcgaa
    58861 gtttgctgag cggtttgaaa aagaatatgt caatcaagga ttctacacga accgttcgat
    58921 tactgaaaca cttgatctag ggtgggaact gctatcgatg ttgccaagaa ccgaattaaa
    58981 acgaatcaaa gacgacatgc tggacaaata tctgccagaa gggaagtgag ttctgatggc
    59041 acgattgaat gtgaatccga cccgcatgga attgactcga ttgaaaaaac agttgacaac
    59101 tgccacaaga gggcataaat tattaaaaga taagcaagat gaactgatgc gtcaattcat
    59161 cctgttgatt cgaaagaaca accagctgcg tcaagaaatg gaagagtcta tgacagaagc
    59221 aatgtctgat tttgtattgg caaatgcttc gatcacggaa cctttcatcg aagaattatt
    59281 tgttttgccg gcggaaaacg ttgatttgtc tatcgtagac aaaaatatca tgagtgtaaa
    59341 agtacctgtg atgaattttg aatatgatga acagctgaca gacacacctt tggaatacgg
    59401 gtatttgaat tccagtgccg aactggatcg gtcaatcgat cggtttacta ccctgcttcc
    59461 aaaacttttg gaactgacag aaatcgaaaa aacttgtcaa ctgatggcga gtgaaatcga
    59521 aaagacacgt cggcgagtca atgcattaga atatatgacg atccctcaat tagaagaaac
    59581 gatctattat attcgtatga agctggaaga aaacgagcgc gcagaagtaa caaggttgat
    59641 caaagtaaaa aatatgggta ccactgacta agtggtatct ttttttaaaa gaggaaaacg
    59701 atgattaaac aaagcaaaca aataaagaaa cgtttgccgg ctgttcagct tctcgcatta
    59761 ggattttttc tcctgatttt agttggcggc ggcctactta ccctaccatt ttttagtaat
    59821 agtgggcatg ggacaaattt tatcgatgcg cttttcactg caacttctgc tgtctgtgta
    59881 acgggattga caacattgaa tacagcagag cattggaaca gtgctggtca atttttgatc
    59941 atgcttttga ttgagatcgg cggtcttggt tttatgatgg ttccgattct atgctttgca
    60001 ttgataaaga agaaagtcag tctcagcaca cgtattatat taaaagaagc gctgaatcta
    60061 gaagaagtat caggtgtgat gaagctcatg ctttacatcc taaaattggc ctttgttatc
    60121 caattgattg gtacggttgc tttatctttt gtatttgtgc ctgaatttgg ctggttgaaa
    60181 ggtatctggt acagtttgtt ccatgcaatc tctagttttt gtaatgcagg gtttgatttg
    60241 ttaggagaca gtttagccaa tcaccagcaa aatgtttatt tgatcatggt ggtatctgct
    60301 ttgatcattt ctggtgggtt aggcttcatc gtatggcgtg atttactgga atatcatcag
    60361 aaaaagaaga tgacgattca ttcaaaaatc gcattaaccg ttacaggtac ccttttatta
    60421 ggcggattcg ttgtgttctt tttcacagag cgcaatgggg caacgctagt ggaagggaat
    60481 atgtttcaac gattggcaaa cacctttttt atgagtgtga cacctagaac ggctggatat
    60541 tattcagttg attacctcca tatgagccat gcaggtctga ttttaacgat gtttttgatg
    60601 tacatcggcg gaacatctgg gtcgacggcc ggcggattga aaacaactac gttaggtgtg
    60661 ttgctgatcc agatgcgttc gatgttgaaa ggacgtacga gagcggaagc atttggccgt
    60721 accatccgac aaggcgcagt gttgcgggca cttactttat tttttgttac gttgacgttg
    60781 tgtgtagtcg ccatcatgat tttatcggtg actgaaacga tacctaaaac ttctggcatc
    60841 gaatatattg cttttgaggt cttctctgcg tttggtacag taggtcttac gatgggattg
    60901 acgccagact tgactgcaat agggaaattg atcattatag cgcttatgta cattggacga
    60961 gttggtgtat tgactgtggt cttctctctg atgacaaaag cacaaagaac acaatcaaaa
    61021 tacaaatatc cagaagaaag tgtcatgatt ggataatttc atcttctgac agaaacctag
    61081 tgatttagta aaataagaaa ataaaataat ttttcttgct tcttggatac tttaagtgca
    61141 aaatgttcgt ttattttttg aggcactacc cgttgttgaa cctcgggtag tgcctctttt
    61201 ttattgaaag gaatcaataa gatttgattc ctttatttat caataggtta taattcatat
    61261 ttttttattt tttcttttac gatacttagt ccagaagcta aaatttcaag gttattagag
    61321 gatagggaaa ttcgaacgaa tgcatctggt tgcgcacgtg tagtaaagcg tctggaatga
    61381 taaagtcgga taccgttagc aagaaagtca ttctcaatta tcttagggtc aatctcagga
    61441 tcaactggaa gaattcgata gtaagggaca cgattcgttg gtttttctac tttgaaaaga
    61501 gaatcaaaaa gctgattggc tctttttgta agacttaatt tagtttctaa gatcctattt
    61561 gcttcatttg aatggaggat ttgagtgatg acttccacat ctaatccaga agttttcaca
    61621 tttatattaa aaattgcttg ttctatcttg ctttggacat gtactggaac tacaagataa
    61681 gcaactcgca atccagaaca aataaatttt gtcattccag ctaagtagat tgtttggtta
    61741 ggtaataaat tttggaaagg aggaatgatc gtatgttgat agtaagttgt taaaaatgaa
    61801 tggatatcat cttcaataac ccatagacct tctttttcaa tcacttcggc taattgctct
    61861 cgtcttttgt gagagatttg aaaccctata ggattattac aagaaggcat aagaaagaca
    61921 ccatgaatct tcttttttct acattcctga atcaatatat caggtcgcat tccttgctcg
    61981 tcaaaatcaa ttggaacgat ctctaaatga tataactgag ccaattcaat gaaattagcg
    62041 tatgtatatc ggtctgttgc tattctatca cctggagaga aaagtgcaga aagtgtgata
    62101 gccaatccat tttgaacacc ggaaacaata gatagagatt ctaaggacgg aatgactcct
    62161 tgagttttta accaatttgc tgcagtagtc aattgaaaat ttgtgccttt gggatcttgg
    62221 taattaagca aaccaacaag atttgggtta ttactagttg attgaataaa cgggacaacg
    62281 aatttattac attcttcaaa agaactaacc agaccaaaat caatgatatg ttcggttact
    62341 tcattggtag agatggtgat ggactcaaag acattgggag aaataaatgt gccacttcca
    62401 atattcgtat acagcaaacc tttctcaatt ccatatttat aagccttgcc aacggtagta
    62461 aaatttaaat ctaaataatc agctagctct ctttgggagg gtaactgagt gtttttctgt
    62521 aatttattct ttaaaatatc ttgttctaat tgttgaatca acgatcgata ataaggacgc
    62581 ttcaattttt gtttgtctgg tcgccaagtt aacgggtaat tgtcataaga attaataggc
    62641 attttctcca ctccttaaaa ttgtatacca tacaatttta ccattgattg tattgatttt
    62701 agaagttaat cttttgtgag gagggaattg tctatgaaaa ttattaattt tgaggaagta
    62761 gtagcttctt ttagttttga agaagcgatt caagtaatga aaaaatgttt ttttgattat
    62821 gaaagtggta aaatcagcca aaatcctcga ttggtggaaa ttttacctga cggaaaaggc
    62881 aaaaatatgt ttgcgatgat gcctgcttat ttgggggaga acagatattt tggcacaaaa
    62941 gtcattaccg cttttccgga taatcatcag tatcatttac cttctcattt aggagagatt
    63001 ttcttgtttg atgctcaaaa cggactaccc aaagcattga taaacgcaaa tgcagtcacc
    63061 tggattcgaa cagctgctgt atctgcgctg gcaacagatt acttagcaaa tccgcatgca
    63121 gaaacacttg ctttaattgg agctggtcaa caagcattgt cgcatttgac tgcgatttct
    63181 accattcgtc ccatcactac agtgtttgtt tacgatattt tagaagaaag acgaaatact
    63241 tttatcgcta aagctaaaaa acagtatcct aaaataacgt ttataaatgc aatatcagta
    63301 gaagatgcag tacgtccagc ggaaatcatt tgtacgttga cctctagtaa agaggcattt
    63361 cttcaaaaag agtgggtaag ggaagacgca catatcaatg ctgtgggcac atttactcct
    63421 gatacaagag agataagtac atcgttgatg gaaacttctc aaatctatgt agatgattac
    63481 tcagctgcct taacagaaag cggggacctg cttatagcca tggcagaagg agatttagag
    63541 gaatcttgta ttgttggtac attaggcgaa ttagtttctg agaaaaaaac attttataaa
    63601 ggagaatcga ggccgacgat tttcgacgca gttggtctag ctattgaaga tctttgttgt
    63661 gcagaatata tttataacaa attagagaaa ggggctttaa aatgaactta gattattacg
    63721 tagttgatgc atttgcagat gaggtgttca aaggaaatcc agcagcggtt tatgtgctag
    63781 aagaatggct gccagaaggt acgatgcaaa aaattgccat tgaaaacaat ttatctgaaa
    63841 cagcatttac agtgaagaaa aaccaagaat ttgagcttag atggtttacg ccagatcgag
    63901 aaatcgatct ttgtggtcac gcgacattag caacagcatt tgttttattt aactattaca
    63961 aaatacctga tgaaacgatt aaattttcta ctcaaagcgg taatctattt gtgacaagaa
    64021 ttaaagatta ttattacatg gattttccta gtattatgcc gaaaaaagtg ccgatattgt
    64081 ctgaatatga agaagcgatt ggggctaaga ttaaagaagc ctacttagca cgtgatttat
    64141 ttttcgtatt agaagatgaa aaaacggtgg ctaaattgca gccagatttt acagctatca
    64201 aaaattttga attaggaata ggagtcatcg tgacagcaga aagtgtgcaa aaagactttg
    64261 tttctagaac cttctttcca aaattaacaa tcaatgaaga tccagtatgt ggatcagcac
    64321 attctaatct tattccttat tgggcagaaa gaatgaataa aacaaaattg tcagcttatc
    64381 aaatgtcatc aaggggcggg gatctagaat gtgaattaaa agaagatcgt gtgataatag
    64441 gaggaaaagc agttttgttt tctaaaggta cctcgtttat ttgatttctt tcaaatgaat
    64501 taaaaataaa ttggtggaga gtggcaacct tatagctaca atggttgtta aaaaaagacg
    64561 caaacttttt caatttaatg aaaagtttgc gtctcatttt aattattggt gtttgttttt
    64621 tattcaatca agagtaaaat gccccatact aactatcctc ggatgacttc gattttataa
    64681 ccatcagggt caatgacaaa gtagtaagaa ggcgcagtgc caggtaatcc ttttaagtca
    64741 gtaatctcaa gaccggcagc tttatgttgc tcgtgtaatt tttctagatc atcagctgct
    64801 atagcgatat gaccatagcc gtctcctaga tcatacgcac catgatcata gttgtaagtc
    64861 aactctaatt catagtcatc cccaggaagt gtcaaataaa caagtgtaaa tttgttttct
    64921 ggaaaatcac ggcggcggct ttcttcaaaa ccaaatgcct tttgataaaa ttcgattgat
    64981 gcttcaagat ctttcactcg aacacatgtg tgagccattt tcatagattc atctctcctt
    65041 ttccttttac tcaatcataa caaaaagaag taaggaaata gttgatttgt gcttgttcat
    65101 gagaaatttc tcatgtaaaa tggatagaaa ataaaactgt taaggtggaa actattcatg
    65161 gataaaccaa tttttggtga aaaaaagcaa tttgctgatt atcaaacccg ttatgcagca
    65221 tatattgtca tagaaagaga tcagcagatt gcagtaatcg aggctccaaa tggtgctttt
    65281 tttcttcctg gcggggaaat tgaaggagaa gagacgaaag aagaagcgat tgtccgtgag
    65341 ctgatagaag aaatgggaat tgtggcagaa atttcttctt atctgggaga agctgatgag
    65401 tatttttact cgaattatcg tgcaacttat tattataatc caggatattt ctttgttgct
    65461 gattcttgga agcgtatagg agaaccaact gaaaagacca ataaaatttg gtgggtgagc
    65521 cctcaagaag cgcttgtgaa attgaaacgt ggtagccacc gatgggcagt cgagagatgg
    65581 atcgaaaaaa ataaaaactg aaagaaagcg agtagatcag ctttctctca gtttttttat
    65641 ttattacagt acata
//
LOCUS       DACDAF010000006        63406 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.006, whole genome shotgun sequence.
ACCESSION   DACDAF010000006 DACDAF010000000
VERSION     DACDAF010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 63406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 63406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..63406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.006"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            164..2698
                     /gene="secA"
                     /locus_tag="IVZ69_000329"
     CDS             164..2698
                     /gene="secA"
                     /locus_tag="IVZ69_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HAP8182448.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDIQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGDE
                     DAVIQSKMLTKQVEAAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIVDFAGSTLVHEDSISLTDIEGKTSQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKDAN"
     gene            2825..3926
                     /gene="prfB"
                     /locus_tag="IVZ69_000330"
     CDS             join(2825..2887,2889..3926)
                     /gene="prfB"
                     /locus_tag="IVZ69_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078989099.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HAP8182449.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRGLFDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAVMQEEAEARI
                     NALDEKMNTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            4031..4717
                     /gene="ftsE"
                     /locus_tag="IVZ69_000331"
     CDS             4031..4717
                     /gene="ftsE"
                     /locus_tag="IVZ69_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HAP8182450.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            4701..5594
                     /locus_tag="IVZ69_000332"
     CDS             4701..5594
                     /locus_tag="IVZ69_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182451.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEKAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFYQLINPSLLRSHYSLIHPENIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            5746..7194
                     /gene="cls"
                     /locus_tag="IVZ69_000333"
     CDS             5746..7194
                     /gene="cls"
                     /locus_tag="IVZ69_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP8182452.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDTLGE
                     EVREALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPEFFPTIHSTGDMAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEVYENRGMMIKMKEGLARLISPLL"
     gene            7531..8388
                     /locus_tag="IVZ69_000334"
     CDS             7531..8388
                     /locus_tag="IVZ69_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HAP8182453.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQAENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            8503..9423
                     /gene="pstC"
                     /locus_tag="IVZ69_000335"
     CDS             8503..9423
                     /gene="pstC"
                     /locus_tag="IVZ69_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HAP8182454.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            9423..10307
                     /gene="pstA"
                     /locus_tag="IVZ69_000336"
     CDS             9423..10307
                     /gene="pstA"
                     /locus_tag="IVZ69_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HAP8182455.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            10322..11128
                     /gene="pstB"
                     /locus_tag="IVZ69_000337"
     CDS             10322..11128
                     /gene="pstB"
                     /locus_tag="IVZ69_000337"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP8182456.1"
                     /translation="MKKYNWNETNVITMPKDKEVALYTNDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYKDVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            11144..11902
                     /locus_tag="IVZ69_000338"
     CDS             11144..11902
                     /locus_tag="IVZ69_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HAP8182457.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWEDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            11915..12592
                     /gene="phoU"
                     /locus_tag="IVZ69_000339"
     CDS             11915..12592
                     /gene="phoU"
                     /locus_tag="IVZ69_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HAP8182458.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            12814..13848
                     /locus_tag="IVZ69_000340"
     CDS             12814..13848
                     /locus_tag="IVZ69_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP8182459.1"
                     /translation="MQKKISIIITLFFICILASWFIQRQAALYDVPVIEIERVRIEED
                     QQLITGRLMNTDQKGEVISLTAPYQKNQIETANITTRQIYLVQMHGDEWQLVAKKNDG
                     WLFFFTSVFIGTMLLIGGKQGVFALGSLIINIVLLLLLLLLFTKTEGISLLNIAILFV
                     VIGIIVSILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYEELNYLTR
                     PYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKQQPKISAKQLWLSGRQVGRDVIGS
                     MANILLFVYISGAIPSLLLYLGNQWSFKETVERHLSLELLRVIAGSLGIVLSIPIAVL
                     FFLAVRRLKK"
     gene            13845..14612
                     /locus_tag="IVZ69_000341"
     CDS             13845..14612
                     /locus_tag="IVZ69_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HAP8182460.1"
                     /translation="MNVLIILVGIFAISVLFVGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILVLSIIGFLLIAVVILFFINGYNLKMRAAFASILIFLFCFLLLIPITDFLAI
                     QGFTSIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     MSFNQLRHASFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDISFQQIINEKSFVL
                     EYTMAILTTLAALLVLPLTCVTTAYLFTKKKEHLKME"
     gene            14712..16280
                     /gene="liaX"
                     /locus_tag="IVZ69_000342"
     CDS             14712..16280
                     /gene="liaX"
                     /locus_tag="IVZ69_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HAP8182461.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDELENSEEKISEPVDPKEKERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEATGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSDDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVNQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATPENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDSIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDDEIAQVQL
                     STTTGSIYLKDTDK"
     gene            16459..16764
                     /locus_tag="IVZ69_000343"
     CDS             16459..16764
                     /locus_tag="IVZ69_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HAP8182462.1"
                     /translation="MKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVAF
                     GSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTKKRKEAEKIDDDEWSDF"
     gene            16764..17114
                     /locus_tag="IVZ69_000344"
     CDS             16764..17114
                     /locus_tag="IVZ69_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HAP8182463.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALFVAILM
                     SLVNVIVSEHNSRK"
     gene            17280..18218
                     /locus_tag="IVZ69_000345"
     CDS             17280..18218
                     /locus_tag="IVZ69_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HAP8182464.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            18233..19063
                     /locus_tag="IVZ69_000346"
     CDS             18233..19063
                     /locus_tag="IVZ69_000346"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HAP8182465.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLVLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGSLPDYDRSLGKNQQII
                     "
     gene            19107..20132
                     /locus_tag="IVZ69_000347"
     CDS             19107..20132
                     /locus_tag="IVZ69_000347"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP8182466.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHHLPDSIRAFTDMEDAVKDADAVLFVIPTKAIRSVAKELVAKLNTKPVI
                     IHASKGLEQGTHKRISEILLEEIPTEKRKAVAVLSGPSHAEEVAKHDITTITAASTNV
                     KAAKYVQELFMNHYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQMMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            20147..21085
                     /gene="galU"
                     /locus_tag="IVZ69_000348"
     CDS             20147..21085
                     /gene="galU"
                     /locus_tag="IVZ69_000348"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP8182467.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYIMSLGKTLEAEGSKINHNPKGITEIKEEKKK"
     gene            21210..21659
                     /locus_tag="IVZ69_000349"
     CDS             21210..21659
                     /locus_tag="IVZ69_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HAP8182468.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTQDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIVTKVGGIGKTTAKATVAGKVGGTAMKFLKTKNILKRQEENKNG"
     gene            21652..22266
                     /locus_tag="IVZ69_000350"
     CDS             21652..22266
                     /locus_tag="IVZ69_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP8182469.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSSELTGIAKEKAQDLSQQAGDLAGNVKQKVSESAEEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDLKKPADELGSIAKDTSEDIMIDVKDAADKAGETVNEG
                     MSEAKPVADDTKEMLKMAKEDAKEDAKEAKKEMKDTMTDSTTNH"
     gene            complement(22329..23432)
                     /locus_tag="IVZ69_000351"
     CDS             complement(22329..23432)
                     /locus_tag="IVZ69_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP8182470.1"
                     /translation="MNNVKINELRQWMAQHQLELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVDRFDAISDILTGTDSYTDLTSIIQRLQLIKTVEEKDKLIEAGKWADVAF
                     EIGFKTVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGSTKVSP
                     NELVLFDLGVIWNGYCSDATRTVAYQKPTEFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLE"
     gene            23642..24643
                     /gene="ccpA"
                     /locus_tag="IVZ69_000352"
     CDS             23642..24643
                     /gene="ccpA"
                     /locus_tag="IVZ69_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HAP8182471.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            24997..25392
                     /locus_tag="IVZ69_000353"
     CDS             24997..25392
                     /locus_tag="IVZ69_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182472.1"
                     /translation="MPKKRRKTIVIILTILTIGIGGKFYMDKREAQKQQDLLAVEKQS
                     VKVLKNTFADIKEVKIEQFEKNDMTGIYEALITMTNTEGKAVYFDYSFTKESNEIDGY
                     GVENEEVQKEGITVDEIIVIYTDGSEEKV"
     gene            25389..26645
                     /locus_tag="IVZ69_000354"
     CDS             25389..26645
                     /locus_tag="IVZ69_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HAP8182473.1"
                     /translation="MTITDKQYKGISNKVYWLDPKHPQYSKSYKEGAIKNFGETKFQI
                     LKIKNSFDGMQAMAVAPIKNGKVDISQVVIAFAGTNLSDWKDLETDARSVMNLYGNRP
                     GASFSEKATTNKILSVSGLKTAGQINSAIAFANEVKKEYGEAAISTTGHSLGGFLALY
                     VAAEKQWKNVGFNGPDPYDLLSPEAKKWVEENPGMLTNYRNHADFIGNFGGNGTGAEV
                     RISMETAYLNLLASHSLTSWKFDENGKLIIPENENNVKARKQQKENQATQLFSYQLQE
                     LNNIRKKLRLSGGRLTVNEQIYLDDTQARLVVEKLSVKMKSAMEEVIRINQRGIFELE
                     KKWQEGLRQARVVAPSLTEQEIIEALASVGATKENLVDSAKEVYLLRINKARRMGEAF
                     DTLAKEIQDKINEIVARDRELAQQFN"
     gene            26657..26980
                     /locus_tag="IVZ69_000355"
     CDS             26657..26980
                     /locus_tag="IVZ69_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182474.1"
                     /translation="MKLEELERDYRSERRQLEAQEDELIHFKNQGLRLMEQEEQRLHH
                     VLKNLALDNEPLFQARRSYSNYQEHYQQALQVERRKLYQQQDELERSYRQKIRQITME
                     KSSYE"
     gene            26973..27239
                     /locus_tag="IVZ69_000356"
     CDS             26973..27239
                     /locus_tag="IVZ69_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182475.1"
                     /translation="MNEFLMQLLKELEKNLHRSNVRSVGMGISQQTWAEKRLTDQNHQ
                     MTAEEATQEFSNRHAHLKESVKGQFAEKLTELFQRQEKKLKQFR"
     gene            complement(27402..29747)
                     /locus_tag="IVZ69_000357"
     CDS             complement(27402..29747)
                     /locus_tag="IVZ69_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP8182476.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLLFAA
                     LGIGIGAGYFAYLVEDTQLPTKKELQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIVLSAQVEKHFSKDEIITTYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSEAYYQKAQQTIQNKGYTIHSTIDKDIYAALQTGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLVGSES
                     RVSDYATTWQEGKNAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINEKITTPFKDVISSLNGNLGNA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSQARIRSANYLANLINQAY
                     QANPEIFGTDEKFDLSSDVMKKKVSGFTGQTAGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANPETKESDDKDD"
     gene            30026..30928
                     /locus_tag="IVZ69_000358"
     CDS             30026..30928
                     /locus_tag="IVZ69_000358"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HAP8182477.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAFMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGAEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKVIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     ISMFKAQAFDPEVFPELLAEEVTL"
     gene            31139..32914
                     /locus_tag="IVZ69_000359"
     CDS             31139..32914
                     /locus_tag="IVZ69_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HAP8182478.1"
                     /translation="MLNILNPLIDQLKKKHTYFILGIAVLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIHYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     ILASILVALAFKPIVKNKYLLLSIYFYFLFSPISFTHEYSTRTYRNALVIPTVEIIIA
                     CLLAIYYRKYNSSKKLLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYGIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFDFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVIGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIAVTSMLVFSKLNLKKALSSK"
     gene            complement(33223..34809)
                     /locus_tag="IVZ69_000360"
     CDS             complement(33223..34809)
                     /locus_tag="IVZ69_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HAP8182479.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
     gene            35060..35284
                     /locus_tag="IVZ69_000361"
     CDS             35060..35284
                     /locus_tag="IVZ69_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HAP8182480.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            35426..37177
                     /locus_tag="IVZ69_000362"
     CDS             35426..37177
                     /locus_tag="IVZ69_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8182481.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQQLEAKIEGGEA"
     gene            37177..38961
                     /locus_tag="IVZ69_000363"
     CDS             37177..38961
                     /locus_tag="IVZ69_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182482.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGVYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFVAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            39296..40147
                     /locus_tag="IVZ69_000364"
     CDS             39296..40147
                     /locus_tag="IVZ69_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8182483.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQNNTYLFTITIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELFQVIQKKYKDTFGCVEKIADFLAETFNYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            40244..42130
                     /locus_tag="IVZ69_000365"
     CDS             40244..42130
                     /locus_tag="IVZ69_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8182484.1"
                     /translation="MGKYQELARKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGIVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTAFLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPVFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNQGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLKAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYMDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(42171..43073)
                     /locus_tag="IVZ69_000366"
     CDS             complement(42171..43073)
                     /locus_tag="IVZ69_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP8182485.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            43303..44706
                     /locus_tag="IVZ69_000367"
     CDS             43303..44706
                     /locus_tag="IVZ69_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP8182486.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMATMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     DLIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            44706..46139
                     /gene="ascB"
                     /locus_tag="IVZ69_000368"
     CDS             44706..46139
                     /gene="ascB"
                     /locus_tag="IVZ69_000368"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HAP8182487.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFPV
                     ITGKKKMFEFDKDHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     NEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDTVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            46284..47210
                     /gene="trxB"
                     /locus_tag="IVZ69_000369"
     CDS             46284..47210
                     /gene="trxB"
                     /locus_tag="IVZ69_000369"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HAP8182488.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            47424..49151
                     /locus_tag="IVZ69_000370"
     CDS             47424..49151
                     /locus_tag="IVZ69_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAP8182489.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLIDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDDEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAMRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     AIIKKMTEE"
     gene            49224..49517
                     /locus_tag="IVZ69_000371"
     CDS             49224..49517
                     /locus_tag="IVZ69_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP8182490.1"
                     /translation="MPDTQKTKVEKVSQLFKMLSDPTRLKILLYLKDGEQNVTAITQA
                     VEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHVLDILNQTLKHVEHQ"
     gene            complement(49611..50471)
                     /locus_tag="IVZ69_000372"
     CDS             complement(49611..50471)
                     /locus_tag="IVZ69_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HAP8182491.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLMQALQDALKEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            50563..50991
                     /locus_tag="IVZ69_000373"
     CDS             50563..50991
                     /locus_tag="IVZ69_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP8182492.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            51153..51329
                     /locus_tag="IVZ69_000374"
     CDS             51153..51329
                     /locus_tag="IVZ69_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HAP8182493.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            51356..51802
                     /locus_tag="IVZ69_000375"
     CDS             51356..51802
                     /locus_tag="IVZ69_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HAP8182494.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(51958..53337)
                     /gene="brnQ"
                     /locus_tag="IVZ69_000376"
     CDS             complement(51958..53337)
                     /gene="brnQ"
                     /locus_tag="IVZ69_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP8182495.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            54043..55014
                     /gene="phoH"
                     /locus_tag="IVZ69_000377"
     CDS             54043..55014
                     /gene="phoH"
                     /locus_tag="IVZ69_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
                     /protein_id="HAP8182496.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDVLYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            55038..57230
                     /locus_tag="IVZ69_000378"
     CDS             55038..57230
                     /locus_tag="IVZ69_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HAP8182497.1"
                     /translation="MLNKTLQKLQKKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSVV
                     LMKFFQLFQTEQAAYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTVILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIIYQGMSFGD
                     ATTWLTLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICRQHHGTTLMRYFYVKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKSEVEKIKEEQEE"
     gene            57247..57723
                     /gene="ybeY"
                     /locus_tag="IVZ69_000379"
     CDS             57247..57723
                     /gene="ybeY"
                     /locus_tag="IVZ69_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HAP8182498.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLELPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISTER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            57701..58102
                     /locus_tag="IVZ69_000380"
     CDS             57701..58102
                     /locus_tag="IVZ69_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HAP8182499.1"
                     /translation="MPMDLKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFG
                     ILALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKD
                     MAAGAVLVTACFSVIVGLILFVPKIYHLLFN"
     gene            58117..59016
                     /locus_tag="IVZ69_000381"
     CDS             58117..59016
                     /locus_tag="IVZ69_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HAP8182500.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            59159..59971
                     /gene="recO"
                     /locus_tag="IVZ69_000382"
     CDS             59159..59971
                     /gene="recO"
                     /locus_tag="IVZ69_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HAP8182501.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRHIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQLMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICERHWSMDDHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRELIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTSEKDMSEKDLPKKEE"
     gene            60357..61274
                     /gene="glyQ"
                     /locus_tag="IVZ69_000383"
     CDS             60357..61274
                     /gene="glyQ"
                     /locus_tag="IVZ69_000383"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HAP8182502.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            61276..63351
                     /locus_tag="IVZ69_000384"
     CDS             61276..63351
                     /locus_tag="IVZ69_000384"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HAP8182503.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKESKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIDAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAQLEKQSEVDPELFENDAEKELHKAVEA
                     MKASFADQTIHENYDQLVALRPLIENYFDQTMVMADEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
BASE COUNT        20738 a        11302 c        13647 g        17719 t
ORIGIN      
        1 ttttttgagt ttcctcctct tttagatgaa atatgaataa attatgaagt tcttacttta
       61 atacgcttaa gatatttcaa ttatctataa ctaatgataa aatgaaaagt aaagtctaca
      121 tagtctggat aatacacaga aggaaaagga gattacacaa cgcatggcca atttgattcg
      181 ttcacttatc gaaaacgata agaaagaact aaaacgttta gatagcattg caaaaaaagt
      241 tgaagcatac gctgaccaaa tggcagcatt aactgatgaa caattacagg caaaaactgc
      301 tgaattcaag ggcagatacc aaaaaggaga aacattagat caattacttc cggaagcttt
      361 tgcagtcgtc cgagaagcag caaaacgtgt attggggtta tatccatacc acgtacaatt
      421 aatgggtggg atcgtgcttc acgatgggaa tatccctgaa atgcgtactg gtgaaggtaa
      481 aaccttgact gcaacgatgc cggtgtatct gaatgcgttg actggcgaag gggtccacgt
      541 agttaccgtc aatgaatatt tagcaacccg tgactcgacg gaaatgggcg agctttataa
      601 tttcttagga ttgacagttg ggttgaatat caactcaaaa tcttcggatg aaaaacgcga
      661 ggcttataat tgcgatatca cttatagcac gaataatgaa ttaggatttg actatttgag
      721 agacaacatg gtcgtttacc gtcatcaaat ggtacaacgt ccgctgaatt atgccattgt
      781 cgatgaagtt gactcgatct tgattgatga agcgagaacg ccgctgatca tttcagggca
      841 agcagaaaaa tcaacagctt tatatacaag agcagacaac ttcgtgaaac gtttgaaaga
      901 agaagaagat tataaaatcg atatacaatc aaaaacaatc agtttaactg aagcagggat
      961 cgaaaaagct gaagaaacat tcggtttgga caacttatat gacattgaaa atactgcatt
     1021 gacccatcac ttggatcaag cattgagagc caactacatc atgcttttag acatcgatta
     1081 tgttgttcaa gatggaaaag tattgattgt tgaccaattt acgggtcgga tcatggatgg
     1141 acgccgttat tcagatggtc ttcatcaagc gatcgaagct aaagaaggcg tagagatcga
     1201 agacgaaacg aaaacgatgg cgacgatcac tttccagaac tatttccgta tgtacaagaa
     1261 acttgcgggg atgactggta cagctaagac agaagaagaa gagttcagag agatttataa
     1321 tattcaagta taccagattc cgacaaaccg tccggtcatc cgtgacgatc gaccagattt
     1381 gctttaccca acattacaaa gcaagttcca tgctgtcgta caagatatca aagatcgcta
     1441 ccgcaaagga cagcctgtct tagtcggaac tgttgcagtt gaaacatctg agttattatc
     1501 agatatgctg aatcaagaac gtattcctca tgaagtactg aatgcgaaaa atcactttaa
     1561 agaagcagaa atcatcatga atgcgggtca aaaaggtgca gtgacgattg ctaccaacat
     1621 ggctggtcgg ggaacagata tcaagctagg gcttggcgta agagaacttg gtggcctagc
     1681 agttatcggg acagaacgac atgaatctcg tcgtatcgat aaccagcttc gaggacgtgc
     1741 aggacgtcaa ggagaccctg gtatgtcaca attctacttg tctttagaag atgatttgat
     1801 gaaacgattc ggttcagaac gaatcaaagc tttcttagat cgaatgaaga tcggtgacga
     1861 agatgctgtg atccaaagca agatgctgac gaaacaagta gaagctgcac aaaaacgcgt
     1921 agaaggaaac aactacgaca cacgtaagaa cgtcttgcaa tacgatgacg tgatgcgtga
     1981 gcaacgtgaa gtaatctata aacagcgtca agaagtgatc atggaagaaa aaagcttatc
     2041 taaaccactg atgaatatgg tcaaacggac aatcagtcgt gtggtagatg cgcatacgca
     2101 attagaaaaa gaaaattgga atttggaaag tatcgtcgat tttgctggca gcacgcttgt
     2161 ccatgaagac agtatttccc ttacagatat cgaaggaaaa acctctcaag aaatcaaaga
     2221 atatctaaac gaacgagcac aagaagtatt caataccaaa gcagctcaat tgaacggacc
     2281 agagcaactg cttgaatttg aaaaagtcgt gatcttacgt gtcgtggact ctaaatggac
     2341 agatcatatt gatgcaatgg accaattacg tcagtcaatc ggcttgcgtg cctatggtca
     2401 aaacaatcca ttagtcgaat accaaacaga aggttataag atgttcgaag atatggtagg
     2461 tgccattgaa tatgaagtca ctcgtatctt catgaaagct gagatccgtc aaaacgtaca
     2521 acgtgagcaa gtttctcaag gaacagcttc tcactcagaa gatggagatg ccaaagaaaa
     2581 cagtaatact agcgcgaaaa aacaaccaat ccatgtgaac aaggttggta gaaatgatcc
     2641 ttgtccttgt ggaagcggga aaaaatataa gaactgtcac ggaaaagatg caaactaatt
     2701 tctgacagca ggattggtga gacaaattct tttttaaaga atttgtctca ccttctttct
     2761 gttatttgac gattctgtta gactagatat aataaaaaaa gtatagtgaa agaaggaaaa
     2821 aaacatggaa atatccgaaa ttcgaaatct cctgacagaa atgcaggaaa aggtcacaag
     2881 cttcaggagg tctctttgac ttagaccagc tggaagaaga cattgcggaa gcagaagcaa
     2941 aaatggctga acctggtttt tgggatgata gcgaagctgc tcaaaaagtg atcagtgaaa
     3001 acaatgcaaa taaagaaact tatgatcaat tccattctct tgctgaagaa ctggaagaaa
     3061 tcgaattgat ggtggagatg ttgcaggaag aacctgatgc agtaatgcaa gaagaagcag
     3121 aagcacgtat caatgcgcta gatgaaaaaa tgaatacgta tgaattatct atgttgttag
     3181 atggtcctta tgatcgaaac aacgccatcg tcgaattgca tccaggggct ggcggaacgg
     3241 agtcccaaga ctggggcagc atgcttttac gcatgtatac acgctgggca gagcagcatg
     3301 ggtatcaagt agagacacta gattatcaag caggcgatga agcaggaatc aagagtgtga
     3361 ccctactgat caaaggacac aacgcatttg gctatctgaa atcagaaaaa ggtgttcatc
     3421 gccttgtacg tatctcgcct tttgactcag caaaacgtcg tcatacttct ttttgttcgg
     3481 tagatgtgat gccagagctt gatgaaacga tcgatataga aatcaatcca gatgatttga
     3541 agatcgacac atatcgggcg agtggtgcag gtggtcagca catcaataag acagaatccg
     3601 ctgtacgaat cactcacttg cctacaggaa cagtagtagc gagtcaggca caacgttcac
     3661 aattgaaaaa ccgggaacaa gcgatgggga tgctgaaagc taagctttac caattagaag
     3721 tggaaaagaa agaacaagaa gcagctgcac tgagaggaga acaaaaagaa atcggctggg
     3781 gatcacagat ccgttcttat gttttccatc catattctat ggtaaaagac catcggacaa
     3841 acgtagagac aggaaatgtc caagctgtta tggacggaga tcttgattta tttattgacg
     3901 gctatttgaa aatgcatctg caataagagc cctttgttaa attgaaataa aattgtaaga
     3961 ttttgcaagc aagttgaaac attgccatgc tataatagct aaagactgaa aaagatatgg
     4021 agagaacgcc atgattgaaa tgaaggatgt aatgaagaag tactcaaacg gtaccactgc
     4081 tatccgcaat ctctcgattg tcatcgaaca aggagagttt gtgtatgttg ttggtccgtc
     4141 tggagctggt aaatctacat tcatcaaatt gatgtatcga gaagaaaaag cttcaaaagg
     4201 aactttgaac gtcgcaggtc atgatctaat agccatcaaa aaccgcgaag ttccttatct
     4261 acgcagagaa atcggcgtgg tgttccaaga ctataaatta ttaccaagaa aaacagtata
     4321 tgaaaatgtt gcgtacgcca tgcaagttat cggcagaaaa cctcgggata tcaaaaaacg
     4381 agtaatggaa gtgctggatc ttgttggttt gaaacacaaa gtccgagtct ttcctagcga
     4441 attatctggt ggggaacaac aacgtgtttc tattgcccga gcaatcgtaa atacacctaa
     4501 agtacttatc gcggatgaac cgacagggaa tctagatccg gaaaactcat gggaaatcat
     4561 gaaactatta gatcggatca atgcacaagg aacaactgtc gtgatggcta cacataacag
     4621 tacgatcgta aatacgattc gacaccgagt aattgctatc gaaaacggcc gcattattcg
     4681 agaccaagcg gaaggggaat atggatacga tgattagaac ctttttccgc catttattag
     4741 aaagtatcaa gagtttgaaa cgtaacggct ggatgacagt agcttcggtc agtgcggtaa
     4801 cgatcacgtt gactttagtt ggtgtgttca tggcggtcat catgaacgca accaaactag
     4861 cacaagatat agaaggaaac gtggatgtat ctgtgttcgt agacattggt acaaaagacg
     4921 aagagatgaa aaaattagaa aaagaattaa atgacttaga tcatgtcaaa aaagtcgaat
     4981 tttcaagcaa agaacaggaa ttgaagaaaa tccaaaacga aatgggcgat tcttggaaat
     5041 tgtttgaagg ggataataac ccgttatatg atgtatacgt agtaagtgct accgatcctt
     5101 cttatacaaa acaagtagca gaaaaagcgg cagatttgaa gaatgtttcc cgttctgatt
     5161 acggtggggc ttcctcagat cggattttcc aaattgctgg tgcagttcga acatggggat
     5221 tagttgcggc ggcattgctg ctgtttgtag caatgtttct catttctaac acgattcgga
     5281 tcacgatttt atctagacag cgtgaaattc aaatcatgcg tttagtaggg gcaaaaaatg
     5341 gatatatccg ctggccattt ttccttgaag gtggttggat cggcttaatc ggtgccattc
     5401 ttccgatact gatcattaca tttggttacg catggtttta ccaattgatc aatccgtcat
     5461 tattacgatc tcattattca ttgatccatc cagaaaatat cgtttggaaa atcaatcttt
     5521 tgatggtcgg tattggtgtg atcattggtt cactcggctc gatcatctct atgagacgtt
     5581 tcttgaaatt ctagtgtcac aagataaata taatcagaaa gttggacgat ttcgttccag
     5641 ctttcttttt ttatcagcta ggtggagtaa atggggcggc ttttttctct ttactttaaa
     5701 aaacaacttg ggtattctta agttggtaga aaaagaggtg aagccgtgaa gattatcgtt
     5761 gacaattttt ttacgatcct tttgattatg aatattttgc tttcctttat tatcgttttt
     5821 cgagaaagaa aggaaactgc gcaaacatgg gcatggctgc tcgttttgat gttcattcca
     5881 gttgtaggat ttattttata tattttttta ggaagaggga tttccaaaga gaaaatcttt
     5941 gatttgaaga tccaagggaa aatcggtaag aatctagaaa tcgaagaaga taaacaagca
     6001 ttgatgcgag ggctttatcc tcatccgcct actggacaag tagatgtgaa acaattgatc
     6061 tatatgctta ctgtatttga aagtacgctt tatacgacta aaaatgaaat cactttattt
     6121 acagatggtc gtgaaaaatt cgatgcgctg atcgaggata tcaaacaggc agaagaccat
     6181 atccatttcc aatattatat ttaccgcagt gatacattag gtgaagaagt tcgagaggca
     6241 ttgacagagg cagcaagacg cggagtaaaa gtcagagtcc ttcttgatgc atggggttcc
     6301 acacaagttt cttctagttt ttttcagaat ttgaaaaaag caggtggaga agtcgcattt
     6361 ttctttcctc tattcgttcc gtatatcaat cctcgaatca attatcgcaa tcatcgtaaa
     6421 atcgtagtga ttgatgggaa aatcggatat acaggtgggt tcaatgttgg aaacgaatat
     6481 ctaggattgg taaagaaatt tggttattgg cgagacaatc atctgcgtat ctatggagaa
     6541 gcggtttaca ccttgcaaaa ccgttttttg atggactgga attctcagca tacaaaagaa
     6601 gtaggatatt caccggaatt tttcccgacc attcattcta caggtgatat ggctgttcaa
     6661 atcgtgacaa gcggaccaga taccgaacat gagcaaatca aaatgacata tttgaaaatg
     6721 atttcgttag ccaaacggga gatattgatc caaacgccgt attacatacc ggatggatcg
     6781 attcatgagg cattgaagtt ggctcttctc tcaggcgtaa aagtccatat ccaaatacct
     6841 aacaaaccag atcatcttct cgtttactgg gcaacgtatt ctttcgctgc agagctgatc
     6901 gagtatgggg caagaatcga aacatatgaa aatggattta tccatgcaaa gacgatgatt
     6961 atcgatggcg gcatcgtttc cgttggttca gctaatatcg acgttcgctc atttagattg
     7021 gattttgaag tcaatacact gatctatgat gaacgaatgg cttctcgcgt aagaaaagca
     7081 ttctttgaag attcaaagat ttcgacgcat ctcacaaaag aagtgtatga aaaccgaggg
     7141 atgatgatca agatgaaaga aggattagca agactgattt cgccgctcct ttaaaataca
     7201 aaaaggacag gagagccatc aatagatgga aatctcgcgt ccttttttct cggggccatt
     7261 tctgagagta cgtcagaaat ggagaaagcg tctcgcatga gcgaaattaa ctttggggta
     7321 tctcttgttt tttggggaaa gcaagaaata agctaatata tgctattaaa agagacacat
     7381 ttcaaagcca gtatagcata gaaactttta atgagatagc tttttttgca attatgagaa
     7441 tttattttgt tatttaatga ttttgattcg ttttcatcaa gtaatgaaaa tgatagaata
     7501 aacatacttt aggattaaag gagatttcta atgaaaaaac taaaattatt cttaccaata
     7561 ataggattag ctattctttt atcaggctgt tcaaagtgga ttgatcgagg agaatccatt
     7621 actgcagttg gctcttctgc cttacagcct ttagtagaaa cggttgctga aacctaccag
     7681 gcagaaaatc ctggaaaatt catcaatgta caagggggcg gaagcggaac tgggttgtct
     7741 caagtacagt caggagcagt cgatatcgga aattctgatt tgttcgcgga agaaaaatca
     7801 gggattgatg cttcggcatt agtcgatcat cgagtagcag ttgttggaat cactcctatt
     7861 gtgaacaagg atattggcgt aaaagatatc agtatggaaa acctgaaaaa attatttacg
     7921 ggcgagatca aaaactggag tgaagtcggt gggaaagatc agccagtagt tatattgaac
     7981 cgtgcatcag gaagcgggac ccgtagtacg tttgaaaaat gggtattgga cggagaaaca
     8041 gctgttcagg cacaagaaca agattcaagc ggaatggtgc gccaaatcgt tgcggacaca
     8101 cccggagcaa tcagctatgt tgctttttct tacgtttccg atgatgtgga tacgttgaac
     8161 gttaacggtg tggaaccaac agatgaaaat gtgacaacga acaaatggac gatttgggca
     8221 tatgagcata tgtacacaag agaccatcca aaaaaactga caaaagaatt tttagactat
     8281 atcttatctg atgaagtaca agataatatt gtcggagagc taggctatat ccctgtttca
     8341 catatgaaag ttgaacgtga ttggcaagga aacattgtta aagagtaatc tttacacaaa
     8401 atttacaaac ttagctaaac ttttacatgt tattaaaacc aaattgatgt tcaatttgta
     8461 cactgagtga gtatgttaaa cctgattaag ggggagtcat ctgtggaaga tgtgaaaaaa
     8521 gtattattaa caaaatcaaa acgttcaaaa atggaacagc gcggaaaatt cattagtttt
     8581 ttgtgtatcg cgctgatcgt gttggttgta ttatctattt tttattttgt cgctagtaaa
     8641 ggattggcca ccttttttac tgataagatc aatgtatttg attttctgtt tggtacagat
     8701 tggaatccaa gccaaatagg agcaaatggg aaacccatgg taggggcatt gcctatgatc
     8761 acaggttcat ttattgtgac ctttttatct gctattgttg ccacaccatt tgctattgga
     8821 gcagcagtgt tcatgacgga gatttctcct aaaaacggaa cgaagatctt gcaaccggtc
     8881 atcgagctac ttgtaggtat tccgtctgtc gtttacggat ttatcggttt atctgttatc
     8941 gtgccttttg tcagaagtat ctttggcggg acagggttcg gtatcttagc tggtacattt
     9001 gtgttattcg ttatgatctt accgactgtc acaacgatga ctgtggatgc attaaaggca
     9061 gtgccgcgac actatcggga agcttcatta gcgctaggtg ccacaagatg gcaaacaatc
     9121 tacaaagtgg tgctgcgagc agcagtgccc ggaattttaa cagcagtcgt ttttggtatg
     9181 gctcgtgcgt ttggcgaagc cttagctatc caaatggtta ttggtaatgc ggcattaatg
     9241 ccaacaggac ttactactcc tgcttctaca ttgacgtcca tcttgacaat gggaatcgga
     9301 aatacaatca tgggaacagt tgaaaataat gtgttatggt cattagcgct gatcttgcta
     9361 ttgatgtcat tattctttaa tatcgtgatc cgtatgattg ggaagaaagg agagctgaaa
     9421 taatgaacgc aaaacgctca gataaaattg ctacaggtgt tctatatgtg gtttcaggga
     9481 tcatcgtatt gatcttagca gctttattac tttatatctt agttcgagga ataccgcaca
     9541 tttcatggtc attcttgact gaaccttcca aagcctacca agaaggcggt gggatcggga
     9601 ttcaattatt taactcgatt tatttgcttt tgattaccat gatcatcagt tttcctatct
     9661 ctttaggtgc gggtatctac ctttcggaat atgccggaaa aaactggctg acagacgtga
     9721 tccgtacgtc tatcgaaatc ttgagctctt tgccttctgt tgttgtcggt ttattcggtt
     9781 tcttggtttt cgttattcaa ttccagtatg gtttctcaat catttctggt gcattagctt
     9841 tgaccgtatt caacttgcct cttttgactc gaacggtcga ggaatcttta caagcggtcc
     9901 attacacaca acgagaagct ggattggcgt taggtttgtc acgctgggaa acagtgataa
     9961 aagtggttgt tccagaagcg acaccaggaa ttttgactgg tgtgatccta agttcaggaa
    10021 gaatttttgg tgaagctgcc gcattgattt atacagctgg tcaaagcgcg ccagcattag
    10081 attttacgaa ctggaatcca ttaagtgttt ctagtccgat cagcattttc cgccaagctg
    10141 aaacactggc tgtccatatt tggaaaatca acacagaagg tacgatgcct gatggtgttt
    10201 ctgtttcggc tggcgcttct gccgtgttga tcattgctgt tttactgttc aacttcggcg
    10261 ctcgtgcgat tggcaaacga ttataccgaa aaatgacttc agcctaagga gaagaagtaa
    10321 aatgaaaaaa tataattgga atgaaacaaa tgtcattacc atgccaaaag ataaggaagt
    10381 tgcattatat acgaatgatc tgcatgtttg gtatggcgac aatgaagcaa tcaagggagt
    10441 ggatctagaa ttcgaaaaaa ataagatcac tgcattgatt ggtccctctg gctgcggaaa
    10501 atccacgtat cttcgttctt tgaatcgtat gaatgatggg attgctaata cgaaaattac
    10561 tggaaagatt atgtataaag acgtggatat caatgcgcct caagtggatg tttatgaaat
    10621 gcgtaaacgg atcggcatgg tgttccaacg ccccaaccct tttagcaaat cgatttatga
    10681 caatataact tttgctttga aacagcatgg tgaaaaaaac aaaaagaaat tagatgaaat
    10741 cgttgaaaca agcttgaaac aagcagcttt gtgggatcaa gtaaaagata gcttggataa
    10801 aagtgccttg gctttatctg gcggacaaca gcaacgtttg tgtatcgctc gtgcaatcgc
    10861 gatgaaaccc gatatcttgc tgttagacga gccggcaagt gccttggatc ctatttcgac
    10921 aggaacggtt gaagaaacac ttgtaaactt gaaagaagac tacacgatca ttatcgtgac
    10981 gcataatatg caacaagcag ctcgtatcag cgactatact gcctttttct atctaggaaa
    11041 agtaatggaa tatgacaaaa caaacaagat atttaccaga ccaaaaattc aggcaaccga
    11101 agattatgtg tccggtcatt ttggttaaga cggaggcctc aacatgacaa aagaaattat
    11161 ctcatccaaa gatcttcatc tgtattatgg aaagaaagaa gcactaaagg gaattgatct
    11221 aagtttcaat caaggtgaaa tcacagcgat gatcggtcct tctggttgcg ggaaatctac
    11281 ctatctacgt tcgttgaatc gaatgaacga tctgattcca aatgtaacga tcaccggaag
    11341 tgttttatat aaagacaaag acatctatgg tccgaaaaca gatgttgttg aactaagaaa
    11401 agaaatcggc atggtgttcc aacagccaaa tccatttcct ttttctattt atgaaaatgt
    11461 catctatgga ttgaagttaa aaggtgaaaa agataaaaaa gtccttgatc aagtagtgga
    11521 agaaagtctg aaggcagcgt ccgtttggga ggatgtgaaa gataaactgc ataaaagtgc
    11581 cttgtcttta tccggtgggc agcagcagcg tgtatgtatc gcacgtgttt tggcagtgaa
    11641 tcccgaaatc atcttattgg acgaaccaac aagtgcactt gaccctgttt ctactgggaa
    11701 aatcgaaagt atgctgttag aattaagaga gcggtatacg atgatcatcg tgacccataa
    11761 tatgtctcaa gcttcacgta tttcagataa gacggcattc tttttagatg gtcacttgat
    11821 cgaatacaac gatacgaaga agatattcat gaatccagaa aaacaagaga cagaagatta
    11881 tatttcaggt cgatttggat aaggaggaaa cggaatgcta cgtacacaat ttgaagaaga
    11941 attgctgaat ctccataatc agttctacga aatggggatg atggtgagca gcgctgtgca
    12001 caagtcagtt cgtgcataca tcaaacacga taaaatctta gctcaagaag ttatcgaaaa
    12061 cgatataaat atcaataata tggaaacgcg tttggagaag aaaagttttg aaatgattgc
    12121 attacaacag ccagttacaa ctgacttgcg tatgattatc acggtcatga aagctagctc
    12181 tgatttagaa cgtatggccg atcatgcggt gtccgttgct aaatccacaa tccgcgtaaa
    12241 aggacagacg agaataccgg aaatcgaaaa agagatctcc gatatgtccg attacgtgaa
    12301 aaaaatggtg gacaacgtcc tagttgcgta tgtcaaaaca gacgaaaaag atgcgcgtac
    12361 aatcgccaat atggatcaaa gagtcaatga ctatttcaat cgaatctata atgcaaccat
    12421 caaaaacatg caagaaaatc ctgaaacagt catcagtggc acagactatt tgaatgttgc
    12481 cagctatcta gaacgaatcg gagactatgt gacaaacatc tgtgaatgga tcgtctactt
    12541 ggctacaggg aaaatcactg aattaaatac gaaccacaat gagattttct aaactgaagt
    12601 tgtgattctg ctgtttattt aggaaaagag gttgtgaaat cagcgttttg tcctgagtat
    12661 tagagaaaca aacggtaaaa tagttcctca tattttgccg ttttttgagc taataccgaa
    12721 ggtcagctga ttgaacaccg tttattctgg aaaagggttt gtgacaaaac atgtcacaaa
    12781 cccttttcat tattccaata gaaaggataa agaatgcaaa aaaagattag catcatcatc
    12841 actctatttt ttatttgtat acttgcttca tggtttattc agcgtcaagc tgctctatat
    12901 gacgtacctg tcatcgagat cgaaagagtg agaatagaag aggatcaaca attgattaca
    12961 ggaagattga tgaatacgga ccaaaaagga gaagtgattt ctttaacggc tccttatcaa
    13021 aaaaatcaaa tcgaaacagc aaatataaca acaagacaaa tctatcttgt ccaaatgcat
    13081 ggagatgaat ggcaactagt agcaaaaaaa aatgatggct ggcttttttt ctttacaagt
    13141 gtcttcattg gcaccatgtt gcttattggt ggaaaacagg gcgtatttgc tttaggaagt
    13201 ctcatcatca acatcgtttt acttttactt ttgttgctcc tctttaccaa aacagaaggt
    13261 atttctctct taaatatagc aatcttattt gtcgttatag ggataatcgt tagtatattg
    13321 gcgttagacg gatggaatag aagcagtata atcaaaattt cggctgcagt tacaagtgtt
    13381 tttttagcat tttttatttg tcttttgaca atgaatcatt ggaaagatca aggactgcgc
    13441 tatgaagaac tgaattatct gacacgaccg tatcgttctg tttttctttc cagcgtgctg
    13501 attgggacag ctggagggac actcgatacc gtgatcacag tcattgcgac attagaagaa
    13561 ttgaccaagc aacaaccgaa aatatcagcg aaacagttat ggctttcagg aaggcaagtg
    13621 ggccgagatg tgattggttc gatggctaat atccttttat tcgtctatat cagcggagcg
    13681 attccatcgc ttctgttata tttaggaaat caatggtctt tcaaagaaac ggtagaacga
    13741 catttatcat tagaactttt acgcgtcatt gctggcagct taggaatagt attatcaatc
    13801 cccatcgcgg tcctcttttt tctcgctgta aggaggttaa aaaaatgaat gtacttatta
    13861 tacttgttgg gatttttgca atcagtgtgc tatttgtcgg tggtacgcaa ggtatgtata
    13921 ttcttttagg attattcatt aatttaggaa tctttttcct attattattc ggctatcatc
    13981 agaagtggcc gatattggta ttgtcgatta tagggttcct attgatcgct gtggttatct
    14041 tattttttat caatggttat aatctgaaaa tgcgagccgc ttttgccagt atactgatct
    14101 ttttgttttg tttcctacta ttgattccta tcactgattt tttagcgatc caaggcttta
    14161 cttcgataga actagaagaa ctatctggct tagataagac gttagcaatt gattttagac
    14221 tacttacgag gtcgttgctt ctgatcagtc ttagcggagc tgttttagat gcgagtgtag
    14281 cgatttctag tggaacattc gaagtatatc aggcaaatcc gcaaatgtct tttaaccaat
    14341 tgcgccatgc tagctttgcc attgctaaaa aaatattggc atcaacagtg atgacgcttc
    14401 tttttgcgtt tatggggagt tctttagcgt tgattctttg gtttattgac ttagacattt
    14461 cttttcagca aataatcaat gaaaaatcat ttgtcttgga atatacgatg gctattctta
    14521 ccacactggc cgcactactt gtcctgccct taacttgcgt gactacagca tatctcttta
    14581 caaaaaagaa agaacatctc aagatggagt aaaagttaca acttaagtcc tatgacattt
    14641 ttactgaatc agtgcataat atggatgtaa ggaaaagctt gcaaacaatt ttgcttaagg
    14701 aggcaatttc catgaaagaa agagaacgta ttttagactt agtgaaaaaa ggaatccttt
    14761 cgactgaaga aggcttagat ttattagaaa gcatggcaac tgaaaaagac gaaaaacaaa
    14821 tcaaaaaaga agcagacaag gtaactgcta gtcataaaga aaaagatcag gcaagtcaat
    14881 tgatcgatga acttgaaaac agtgaagaaa aaatttctga gccagttgat ccaaaagaaa
    14941 aagaaagaca agatcaagaa aacttagaaa agatcttaga tgaactagca actgaagcga
    15001 ataaaacttc ggcgcgtcta gacgaagtaa atgctcaatt cgctgacaat aaggcagcac
    15061 gtaatgagaa acaggaagca ttgatgcagc tgaatacaaa agaagaatta ggcgagttga
    15121 cagaagaaga attagcacag cgtcaaacgt tagaagcaga aatcaaagag ttagaagcaa
    15181 ccggcgatac actattagaa gaacaattga agctggaagc agaattaaaa gatatccgca
    15241 agaatcaatg gtctgagaaa aaagaaacat ttacggataa gtttgaattg ccagatgatt
    15301 ggaaagatca agcgacagat acgctgaatc aagtaggcga aaaaatgtca gaagctggat
    15361 cacagttagg caaattcttg aagaaaacat tccaaactgt ttcagaaaca gtaaatgata
    15421 acatggaatg gaaagatgtc agcttacgcg tccctggaat tgcgacaacg aaatttgaac
    15481 acgaatttta ttatgaagct cctgcagcaa gtatccttga tatcaaggca gcaaacggaa
    15541 acgtgacgtt aaaaacgtgg gacagtgatg atgtgaaagt ggaagccaag atcaaacttt
    15601 acggaaaaat gggtgctgaa ccatttgaag cattctctga acggagccag atcgaggtca
    15661 atgaagatca tatctccttc caaattccaa ataagcgtgt gcgtgcagac cttgttttct
    15721 acttgcctaa acgagtatac gaccatgcag ctatcaaact tctaaatggc aacatcatga
    15781 ttgagacatt ggaagctaaa gatatttata caaaatctac gaatgggaac atcatcgtga
    15841 accaattaac tgcaacgatg ctggaagtag aaggtgtaaa cggcaatatc gatattcgaa
    15901 acgggaacat cttagattct attatagaaa cagtaaacgg tacagtgaca tttggtgcca
    15961 caccagaaaa cctttctgtg tctttagtaa atggtgatgt acgtcttacg attaaagaag
    16021 ataatttgaa aaaagtagaa gcaagttcag tgaacgggaa tgtcaaagtt gctttaccag
    16081 atagcatcgg tttggaagga cacgctaaaa caagtcttgg aagcattaac agccgtctgt
    16141 ccaattacga agtagttcgt gagaaaaaag aacggacaaa ccaaatgttg caattccgtc
    16201 gtgtttcaga tgatgagatc gcacaagtgc agctttcaac gacaacagga agtatctatt
    16261 taaaagatac agataaataa agaggttgtg aaagagatgt tcagccttga gcaataagaa
    16321 gcgatttttt aaaatagctt cccctatttt aaaaaaatgt gccttattgc cgataggcta
    16381 tctcttgaac accgattaag aagaaggttg tcacaacgat tttcttcatt taaaatagta
    16441 gaacagaggt gagacatgat gaaaaaaaag ttgacaaaat ccaataaaaa tgttgttttg
    16501 acaggtactt tagcagggat tggggaatat atcgggattg atcccactgt tatccgtgtg
    16561 ctttatgtat tcttaagctt agttgctttt ggaagtccaa tcattttata cattttatta
    16621 gctttgatta tcccatctgc gcgttctgca cgaacaaact atggacataa caatgcatat
    16681 tatgaaaaaa acaattatcg tgaacaaaca aaaaaacgca aagaagcgga aaaaatcgat
    16741 gatgacgaat ggagtgactt ttaatgtcgt actttcagcg tattttggtt aatacgttaa
    16801 cattcatatc gttggctgtt ctttttcctg cgatggtcca tgtgagcagt atttggacgg
    16861 ccgtccttgc cagcttcgta ttatctgtgt tgaacatgtt tgtcaaaccg attttgacga
    16921 tcctgtccct gccctttaca ttagtcacat tgggattgtt tacgtttgtt atcaatgcag
    16981 cgattcttaa aatgacttcc ttttttgtag gagcagaaca ttttagtttt tcttcatttg
    17041 gtgcagcgtt attcgtagct atcttgatgt cacttgtcaa tgtaattgtt agtgaacata
    17101 acagcagaaa ataaaaaaag ctgtgccgag atctcggcgc agcttttttg tttagaataa
    17161 agaatgcgtt ttctattaca ttggtaatta aataaaaacg ttttttttaa ttggtagtac
    17221 ttttggctag acaatgataa aatgatagag aacactctaa tagaaatgag gtagcatgaa
    17281 tgtcagaagt tgtaaaagtt agccaattag taaaaaaatt atctttggaa atcgtcacag
    17341 gcgacgagaa aagtttagac cgcgtcatcg tgactgggga catctcacgc ccaggactag
    17401 agttgaccgg ttattttaat tattattccc ataatcgttt acagctattt ggcagtaaag
    17461 aaatcagttt tgcggaacgg atgatcccag aagagcgttt gatcattatg agaagattat
    17521 gtagtgaaga tatgcccgca tttattattt caagaggatt gccggctccg gaagaaatga
    17581 tccaagcagc caatgaaaat gggatagctg tgctgcgttc gcctatctca acgtcccggc
    17641 tgctaggtga attatctagt tatttagatg gacgcttagc ccctcgaaca agtgtccacg
    17701 gtgtgttagt cgatgtctac ggattaggtg tactaattca aggggacagt gggataggga
    17761 aaagtgaaac ggcgttggaa ctgattaagc gcggacatcg attgatcgca gacgatcgag
    17821 tagatgtcta tcagcaagat gaactgacgg taatcggaga acctcctaaa atcctggaac
    17881 atctgattga gattcgaggg atcggtatca tagatgtaat gaatcttttc ggtgcgagtg
    17941 cggtacgagg ctctatgcaa gtccagttag ctgtttatct agaagcatgg gcgaaagata
    18001 agaaatacga ccgtctgggc tctgaagaca cgaccgttga aatcgcggaa gtgggcattc
    18061 cacaaataaa aatccctgtc aaaacaggac gaaacgttgc aatcatcatt gaagtagccg
    18121 caatgaattt ccgcgcacgt acaatgggct ttgacgcaac gaaaacattt gaagaaagat
    18181 taagtcgctt gattgaagaa aactcaggca atgactagca aggagtgaca atatgttagc
    18241 acaaatcaat cgagttgctt ttgagcttgt aggaattcct atctactggt atgcattgat
    18301 tatcgtatca ggaatcatta ttgccatgtg gctcagcagc agagaagctg ttcgggtagg
    18361 attaaaagca gatgacgtga cagattttat gttgtgggga ttgccgattt ccattattgg
    18421 tgcccgcttg tattatgttt tattcgatct tccccaatat atagctgatc caatccagat
    18481 attcaatatc cgttcaggag gattagcgat ttacggggga ttgattgcag gtgcaatcac
    18541 actgtacttt tttaccaaat atcattttat ttctttgtgg acctttttag atatcgctgc
    18601 accaagcgta ttattggcgc aggcaatcgg acgatgggga aatttcatga accacgaagc
    18661 gtatggtcca gacacgacac gaagtttctt agaaagtctg catttaccgc aattcatcat
    18721 tgataacatg tatatcgaag gaatctatcg acaaccaacc tttctttatg aatcactttg
    18781 gagtttgatt ggatttattc tgcttttggt tttgcggaag aaaccacatc ttttgaaaaa
    18841 aggagaagtc cttttatgtt atctaatgtg gtatagtttc ggacgtttct ttatcgaagg
    18901 gttacgcaca gacagccttt actttttagg tgtgatccgc atttctcaat tattgtctgc
    18961 tgttttattt gtcggcacat tgattctgtt tatttggcgt agaaaaaaag gaagtttacc
    19021 ggattatgac cgctcattag gaaaaaatca acaaattatt tgattttcag agcgttaaaa
    19081 atgaaaaaaa tttcaggagt ggtaaaatga attatagagt agcggtttta ggaccaggct
    19141 cttgggggac tgctttagca caagtcctcg ctgaaaacgg acatgacgtt cggatttggg
    19201 gacatcgtgc ttcacaagta gaagaaatca acacccaaca caccaatcaa cgttatttac
    19261 cagatcatca tctacccgat tccatccgag cattcaccga tatggaagat gcagtaaaag
    19321 atgcagatgc ggtactattc gttatcccga cgaaagcgat acgttctgtt gcaaaagaac
    19381 tagttgccaa attgaatacg aagccagtga tcatccacgc aagtaaggga ttagaacagg
    19441 gaacgcataa aagaatctct gaaatcttgt tagaggaaat cccgacagaa aaaagaaaag
    19501 ctgttgctgt tctttctggg ccaagccatg cggaagaagt agcaaagcat gacattacga
    19561 cgatcacagc ggcaagcaca aatgtaaaag cagcaaaata tgtacaagag ctgttcatga
    19621 accattattt tcgaatctat accaaccctg atgtgattgg tgtagagatg ggagcagctt
    19681 tgaaaaatat tattgccatt ggagctggtg ctattcacgg cttagggttt ggcgataatg
    19741 caaaagcggc aatcatgacg cgcggattag ctgagatcag ccgtttaggt gtagcaatgg
    19801 gtgccaaccc gctgaccttt attggcttaa gcggagtagg tgatctagtc gttacttgca
    19861 caagtgttca ttccagaaac tggcgcgcag gcaacttgtt aggacaaggt cagcctctag
    19921 aagaggtgct agccaatatg ggaatggttg ttgaaggtgt gaatactact caagcagcga
    19981 tggaactagc ccaaatgatg gaaatcgaaa tgcccatcac tcaaacaatc tatgaagtgc
    20041 tgtatgaaca aaaagaaatc aaaacagccg caaaagaaat catgttacgt gatgggaaaa
    20101 aagaaaatga attctcatta acaatttttt gaaggagcga atgtatatga aagtaaaaaa
    20161 agcagttatt ccagcagcag gattaggaac aagattttta ccagcaacaa aggcgatggc
    20221 aaaggaaatg ttgccaatcg tggacaaacc aacgatccaa ttcatcgttg aagaagcgtt
    20281 gaaatcagga atcgaagaca tcttgatcgt tacaggaaaa gctaaacgac caatcgaaga
    20341 tcactttgat tcaaatatcg aattagaaac aaacctaagt gaaaaaggaa aaaccgaatt
    20401 attgaaatta gtagaagaaa cgacagatgt caatttgcat ttcatccgtc aatctcatcc
    20461 aaaggggtta ggacacgccg ttcttcaagc aagagccttt attggaaatg aaccgtttgt
    20521 cgttatgcta ggcgatgata tcatggaaga cgaagtacca ttgacacagc aattgatcga
    20581 tgactatgag cgtacacacg cttctacgat tgccgttatg caagttcctc acgatgaaac
    20641 ttcaaaatac ggaatcatca acccagggga agtactggaa gatgggttat acaatgtcaa
    20701 aaactttgtt gaaaaaccag atccaagcaa agcaccaagt gatttagcta ttattgggcg
    20761 ttacttattg actccagaaa tctttgatgt attatcagaa caacaaccag gcgctggaaa
    20821 tgagatccaa ctaactgacg caatcgatac gttgaataaa acacaacgcg tatttgcccg
    20881 taaattcaca ggtaaacgtt atgacgttgg tgacaaattt ggttttatga aaacaagtat
    20941 tgaatatggt ctgacacatc cagaagtagg ggcacctttg cgtgaataca tcatgtcttt
    21001 aggtaaaaca ttagaagcag aaggaagcaa gatcaatcat aatccaaaag gaataacaga
    21061 aatcaaagaa gaaaagaaaa aataatcttt ttttctaacg agcttcagct gctaattgaa
    21121 taaaaagtag ttgaagctcg tttttatttg tttaaaaaac acgaaaatgc tatccttata
    21181 gaaaagagag acaagaaggg agtttgatca tgtcaggagg agaaattgca ggattgatcg
    21241 cagcaatcgc ctttgcgata cttgtcgttt tcatcgttcg cgtattgttg caagtttcca
    21301 aaactttaga aaaagtagac cagactgtcg cagaagcaaa tacgacaatt gagatcgtca
    21361 cacaagacgt agatctttta tctagacaag tagaaggctt gctagtcaaa agtaatgagc
    21421 tgctcttgga tatcaatgga aaagtcgcaa cgatcgatcc attgttcaca gcagttgctg
    21481 atttaagtga aagtgtatcg gaacttaatc attctagtaa aaacatcgtg acgaaagtcg
    21541 gcggaatcgg aaaaacgaca gctaaagcga ctgttgccgg aaaagtcggt ggaacagcga
    21601 tgaaattttt aaaaacaaaa aacatactga aacgacagga ggaaaataag aatggctaaa
    21661 aaaggtggat ttttattagg tgcagtagtt ggaggtacag ccgcagcaat cgccgcatta
    21721 ttgttagcac ccaaatctgg taaagaactt cgggatgaat tggctgctca agcagatgat
    21781 ttgatggaca tggcttcaga ttacacagat atggcaaaag aaaaatcatc tgagttaaca
    21841 ggtattgcaa aagaaaaagc gcaagatctt tctcaacaag caggggatct agcaggcaat
    21901 gttaagcaga aggtaagtga atcagcagag gaagcaggaa gcgaatcaga tgatatcttg
    21961 ttaaacctca aagaacaatc agctgattta tctaatcgtt tcaaaaaaac agcagaagat
    22021 ctgaaaaagc cagcagacga attaggtagt attgctaaag atacttcaga agatatcatg
    22081 atcgatgtaa aagatgctgc agataaagca ggagagacgg tcaatgaagg aatgtcagaa
    22141 gcaaaaccag ttgcagatga cacaaaagaa atgttgaaaa tggcaaaaga agatgcaaaa
    22201 gaagatgcaa aagaagctaa aaaagaaatg aaagatacaa tgacagattc gactaccaat
    22261 cactaagatt actcatttct agaataaaaa aggtgagagc ggaccagctc tcaccttttt
    22321 tattttcatt actctaaaac aagtaattct tttggtgtag tcgtgaatgg cacacaacca
    22381 tcacttgtca catacacaca atcttcgata cgtaccccta ctttttcagg aatatagatt
    22441 cctggttcaa gagagaagca catcccttct tcaatcacta agtcgtttcc ttctacaaga
    22501 gaagggaatt cgtggacggt tgttccgatt ccgtgaccta aacggtgatt gaaatattcg
    22561 ccgtagccat agctgttgat cacgtttcgt gcgatttgat caagttcacc tgctgtcaca
    22621 cctgggcgaa ctgcctcttg tgcggcaagc tgtgcttcaa gagtgatgtt atagattttt
    22681 tcttggaatt cagttggttt ttgataagca actgtacgag tagcatcact gcaatagcca
    22741 ttccaaataa cgccaagatc gaataacact agttcatttg gtgaaacctt cgtgcttcct
    22801 ggtgtaccat gagggcttgc agcatttgct cctgcaagga ctaatgtgtc gaaagacatt
    22861 tgtgaaacac cttgtttttt taattggtat tcgatttctg cgataattgc ttgttcagtt
    22921 acgccttctt ttactgtttt gaagccaatt tcaaaggcaa catcggccca tttaccagct
    22981 tcgatcagtt tgtctttttc ttctaccgtt ttgatcagtt gcagacgctg gataatagaa
    23041 gttagatcgg tgtaagaatc tgtacctgtc aagatatcag agatagcatc gaagcgatcg
    23101 acagtcagag cattcttttc aatacctaca ttaccaggtt gcccatagcg tgcgcgaagc
    23161 tcttttccga tgatctccca aggattttcg ctgtctaagt agccacgtac atcgtacgcc
    23221 cagctgctgt tttgagcatc ttcaacttcc agagcaggag tgaaaaggaa aggatcttgt
    23281 tccagaggga taaaaagagc tagtacacgc tcgtgaggat cactttcata tccggaaaag
    23341 taagcgatgt ggccagggtc gctgatataa gccaattcta attggtgttg tgccatccat
    23401 tgacgtagtt cattgatttt tacgttattc atttggcaac ctactttcta aattaatttt
    23461 gtattcaata attgtaccac tgattgatta aaagaccaac gttcttaaaa ctgaaaaaag
    23521 taaaaatttt catgaaaaca gagataaaac ggttgcaatt gttgagatta tttgatatcc
    23581 tattttagaa atgtaagacg tattttcaga aaacatataa aatatgaata ggagaacaca
    23641 aatggaaaag caaacaatca ctatctatga tgtagcgaga gaggcaaatg tttcgatggc
    23701 tactgtttca cgtgtcgtaa atggcaatcc aaacgtcaaa ccagcaacaa gaaaaaaagt
    23761 cttggaagtt atcgatcgct tggattatcg tccaaatgca gtcgcacgtg gcttggcaag
    23821 taagaaaaca acaacagttg gggtaatcat tcctgatgtc agcaatatgt tctttgcctc
    23881 tttagcacgt ggtatcgacg atgtggcaac aatgtacaaa tacaatatca tcttagcaaa
    23941 ctcagatggc aacgatcaaa aagaagtcaa tgtattgaat aatttattgg ctaagcaagt
    24001 ggacggcgtg atctttatgg gtcaccatat cacagacgaa atccgtggag aattttcacg
    24061 ttcaaaaacg cctgttgtac tagctggttc cattgatcca gatgaacaag taggtagcgt
    24121 aaacattgat tatgtatcag caacaaaaga tgcagtaaat aaattagcaa aaagcggcaa
    24181 taaaaaaatc gcttttgtca gcggtgcgct gattgatcct atcaatggtc aaaaccgtct
    24241 aaaaggctat aaagaagcat taagcgaaaa caatctacca tatagcgaag gattgatttt
    24301 tgaggcacaa tacaacttta aagatggtct gtctctagtt gaccggatcc ataatagcgg
    24361 tgcaacagct gtctatgttt cagacgatga attagccatt ggtatcttgg atggtttatt
    24421 agaccgcggc gtaaaagtac cagaagaatt cgaaatcatc acaagcaaca attctttact
    24481 gacagaagta gctcgtcctc gtttgacaag tatcacacaa ccattatacg atttaggagc
    24541 ggtatccatg cgcctattga cgaaaatgat gaataaagaa gaagtcgaag aaaaaacgat
    24601 tatcttgcct tatggaatcg aagaaaaagg atcaactaaa taataaaaga tcaatcattt
    24661 aaaggttgtt cccaaagtgg tcaacttctg gaacaacctt tatacgagaa aaggggttat
    24721 gacaaaattt tgtcataacc cctttttttg tgactttaaa aaaaagagag aatggcggaa
    24781 acaaacctta cgtccatcgt atacgacaca atctgtgcgt agatgctaca ttttgttcac
    24841 tactatcaaa attactttaa aatgaaaacg tgataaaaaa gaaagtagaa aagtagaaaa
    24901 gtaactctaa aaaatccaaa aaaatccagg ctcgattgcg tacttatctt aaaggagaaa
    24961 caatccatca tacataaccc gaaaggagac ttctatttgc ctaagaaaag acgaaagacc
    25021 atagtcatca ttttgaccat tcttactata ggaatcggag gaaaatttta catggacaaa
    25081 agagaagcgc aaaaacagca agatttactc gcagtagaaa aacagtccgt caaagttctg
    25141 aaaaatacct ttgcggatat caaagaagtg aaaatcgaac aatttgagaa aaacgacatg
    25201 acaggaatct atgaagcatt gataacgatg accaatacag aaggaaaagc cgtttatttt
    25261 gattatagct ttacaaaaga aagcaatgag atagatggct atggtgttga aaatgaagaa
    25321 gtacaaaaag aagggattac ggttgatgag attatagtta tctatacaga tgggagtgag
    25381 gaaaaagtat gacaattact gataagcagt ataaaggaat aagtaataaa gtatattggc
    25441 tagatccaaa acatcctcaa tatagtaaaa gttacaaaga aggcgccatt aaaaactttg
    25501 gagaaacaaa attccaaatc ctaaaaatca aaaactcctt cgacggcatg caggcgatgg
    25561 ctgtagcgcc aatcaagaac ggtaaagtgg atatttctca agtagtgatt gcttttgcag
    25621 gaacgaactt aagcgattgg aaagatttgg aaacggatgc aagaagtgtt atgaatctct
    25681 atgggaatag accaggagca agtttttctg aaaaagcaac aacaaacaag attttatccg
    25741 ttagtggatt gaaaacagcg gggcaaatca attcagcgat tgcatttgct aatgaagtaa
    25801 aaaaggaata tggagaagct gctatttcta ctaccggcca ttcattaggt ggattcttag
    25861 cattatatgt agcagcagag aaacaatgga aaaatgtcgg cttcaacggg ccggacccgt
    25921 atgatctctt atcaccagaa gcaaaaaaat gggtggaaga aaatcccggt atgctcacca
    25981 attaccgaaa tcacgccgat tttatcggta attttggtgg taatggcaca ggtgctgaag
    26041 ttcggatcag tatggaaaca gcatacttga atctgcttgc ttcccacagt ttaacctctt
    26101 ggaagtttga tgaaaatgga aagctgatta ttcctgaaaa tgaaaacaat gttaaagctc
    26161 gaaaacaaca gaaagaaaac caagcgaccc agttgttttc ctatcagttg caagaactga
    26221 acaacatacg taaaaaacta cgattaagtg gcggccggct gacagttaat gaacaaattt
    26281 acttagatga cacacaagct aggttagtgg tggaaaagtt atcggtaaaa atgaaaagcg
    26341 ctatggaaga agttatccgc atcaaccaaa gaggaatttt tgagctagag aaaaaatggc
    26401 aagaaggctt gcggcaagca cgtgttgtcg ccccttcgtt gactgaacag gaaatcatag
    26461 aagcattagc tagtgtgggc gccacaaaag agaacttagt cgattctgcg aaagaagtct
    26521 atctgctacg aatcaataag gcaagacgta tgggggaggc ctttgataca ttggcgaagg
    26581 agatccaaga caaaatcaat gaaatcgtgg cacgagatcg agaattagca cagcaattca
    26641 attaaaggag aagtagatga aactagaaga attggaaaga gattatcgaa gtgaacgaag
    26701 acaattagaa gctcaagaag atgaattgat ccactttaag aatcaaggat tacgattgat
    26761 ggagcaagag gagcagcgac tgcatcatgt attaaagaac ttagctttag ataatgagcc
    26821 tctgtttcaa gcaagacgaa gttattcgaa ttatcaggag cattatcaac aagccctaca
    26881 agtagaacga cgaaaactct atcagcagca agacgaacta gaacgttcct atcgtcaaaa
    26941 aatcagacaa ataactatgg agaaatcatc ttatgaatga atttttaatg caattactaa
    27001 aagaattaga gaaaaatcta catcgatcaa atgtacgttc agttggtatg gggatatctc
    27061 agcaaacttg ggcagaaaaa cgattgacag atcaaaacca ccaaatgact gcagaagaag
    27121 ctactcaaga attttctaac cgacatgcac acttaaaaga atcagtaaaa gggcaatttg
    27181 cagaaaaact aaccgaatta ttccaaagac aagaaaagaa attaaaacag tttcgttagt
    27241 aaagttatat agaaaaattt tgtgaaaatg gtttttcaca tttttacata aatttgtctt
    27301 aatatcgtag atgtaagctt ttgaacacca tttattcgga aaaagggagc tgtgacaaga
    27361 tttttgtcgc agctcccttt aattctgatt aatctattag atcaatcatc tttatcgtct
    27421 gattctttgg tctctggatt cgctctagca taagctgaag cggtgttcca gtaatctgta
    27481 tagttttcat cagtaccgcc aacgccgaat ttaaaggcgc ttttcttcgg accatttttt
    27541 gcccaaagtg attccactgt ttttcctggc gtttggatag attttttatt gacagtaact
    27601 tttccagctg tttgtcctgt gaacccagat acttttttct tcatcacatc ggatgataag
    27661 tcaaatttct catcagtgcc gaaaatctca gggtttgctt ggtaagcttg attgattaga
    27721 ttggcaagat aattagccga acgtattctt gcttggctgt ccattccagt attgtcatcg
    27781 tgtcctgccc aactactgat agtgatagat ggagttgaga cgatcagcca tgaatctcgg
    27841 tattcattgg tagaaccagt ttttccgacc caatctgcat ttcctagatt tccgtttaag
    27901 cttgagatga catctttgaa tggtgtagtg attttttcat tgatcacact acgcatcatg
    27961 tcattcatga tcgatgccgt tgcttcggaa taaatacgga cagaattact ttcatgttta
    28021 taaatcacat tacctgcatt atctgtgatg gaatcaatga tatagccttc ttcgtagact
    28081 ccaccatttg ctaaggcctg gaatccattt gtctgttgaa gcgtcgttac atctactgtc
    28141 cctaaaggag ccgattcaac gccccaatta tcatttgctg ggtagttcat cttcgccaag
    28201 tagtgctcgt aagcgtattg tttcgatcca ccggaattca acacatcttg atataagtga
    28261 taagctggga tattgttgga ccattccagt gactcacgga cggtttggaa ggtgttcgac
    28321 ccttcattgg tcgcattgac gattttctca ccagcatttt ttccttcttg ccaagtcgtt
    28381 gcataatctg atacacggga ttctgatccg acaagtccca tatcgattgc aggaccgtaa
    28441 acaagaaccg gtttgatgga tgaaccagct tgacgttctg tatcaaaggc gtggttattt
    28501 tgattctggc tgtaattccg accacccacg aagccataga tacgtccggt tctgttatcc
    28561 atcaatacat ttccagtctc cacttggcta ccagcaccat catctaacat gtagccataa
    28621 ttttctacgc cggtttgcaa tgcagcatag atatctttat caatcgtcga atggatcgta
    28681 tatcctttgt tttggatcgt ttgctgtgct ttttgataat aagcttcact gaccgatgaa
    28741 tctgacatat cagcattatc tttttctgcc aattgttgtg caataatcct tgttgcttcg
    28801 ttcatcacgg tataatacaa gaattctctg tcagtctgtt ccgcgatttg ttgtgggaga
    28861 aagtcttttg taagatcata ggctttcgct tcttcgtatt gttctttcgt aatttgtcct
    28921 tcacggtaca tactgaataa aacaaaatct tttctggcaa gaccggcaga aagatcttct
    28981 tttagcgcgc ctgtattcgt gtatggacta tacgtgatag ggctttgagg caaaccagcg
    29041 atataagcag cttgcggcag agtcacatcc tttgcatcta caccaaagat tcctctagca
    29101 gcttcctgga ctccagcaat attttgcccc ttattattcc gaccaaatgg tgagacattc
    29161 aaatacgtag taatgatctc atcttttgaa aagtgttttt ctacttgtgc agaaagaacg
    29221 atctcgtttg ctttacgttt gaatgttgtt tcatcggtta ggatctgttg tttgactaat
    29281 tgctgtgtca aagtggatcc tccagacgag ccgatgccag tcgcttctga aactagtgct
    29341 cgtaaaacag ctttagggac ataaccttgg tgtttatcga agtattcatc ttctgtactg
    29401 ataatcgcgg ttttcaataa aggcgaaatc ttatcagatg aaatagtcgt ccgcatcaga
    29461 tctgtctgga tttttgatat ctctgtatta tctgcataaa caatctttga cgtttccgta
    29521 atgtttccta gttctgtctg cagttctttt ttagtcggca attgtgtgtc ttcgacaaga
    29581 taggcaaagt agccagcacc tattccgata cctagagctg cgaacaacaa aagaagaaca
    29641 gtaataaaaa cagtcaatga ttgaaacact ctaaaaataa tcttaggaac aaaccatttt
    29701 tctttttttc ttctattctg tttttttcga gtatttttgc gtggcaaaag ggtcacctca
    29761 actaatggtt ttatttcgct aattatagca aataatagga caaaaaaaca gacaaggctg
    29821 tttttgacag gaatttcttt ttcgaatgag ataaaacgtg aggaaatgat cttttttatg
    29881 aaagagttct taagcttttc tttagggaaa gtttcagtta ctatggagaa cagggcaaag
    29941 aaaaacaaac tattttcttt gtacatcatc ttatcaatat acaggaattg ttcgaaacaa
    30001 ttgcctttca aggaggaatc catccatgtt attaggctca cacgtcagca tgagcggaaa
    30061 gaaaatgctg ttaggcgcgg cagaagaagc agccagttac ggatcttcga cctttatgat
    30121 ctatacaggc gctcctcaaa atactagaag aaaagctatc gaagagatga atattgatgc
    30181 cggaaaagca tttatggcag aaaacggact aacaaatatc gtcgttcatg cgccttatat
    30241 cattaatttg ggaaatacga tcaaaccaga aatgtttcca tttgctgtac aatttctgag
    30301 agaagagatt gtccgtgcgg aagctttagg tgctactcaa atcacccttc acccaggcgc
    30361 tcatgtagga gcaggggcag aagctgggat tgctagaatt attgaggggt tgaatgaagt
    30421 tttgacaaaa gaacagacgg cacagatcgc tttggagacg atggcaggga aaggtacgga
    30481 aatcggtcga acatttgagg aattagcgca aatcatcgat ggagtaaaat tgaatgaaaa
    30541 attatccgtt acttttgata catgtcatac gaatgatgcc ggatataata taaaagaaga
    30601 tttttcaggt gtaatggaag agtttgataa ggtcatcgga ttagatcggc ttaaagtact
    30661 gcatatcaat gattctaaaa atcctcaagg ttctcataaa gatcggcatg ccaatatcgg
    30721 ttttggaaca attggatttg acacattgaa caaaatcgtc catgatccaa tgtttgacaa
    30781 catttcgaaa atattagaaa ccccatatgt cggtaaagat aaaaagaaag cttacgcacc
    30841 atatggaaaa gaaatttcca tgttcaaagc gcaagcattc gatcccgaag tgttccctga
    30901 gttattagca gaagaagtca cactttaagt tttctacctg acagcaacaa aaaaggattg
    30961 ggcagtctgc cttgtccttt tttgtttaag aaacaaagga gtgctttttg cattcgtttt
    31021 cgccatgctc cttttgcccc ctctttttaa attcagacaa acagggtata ctgatagaaa
    31081 agtaaaaaac gaaaagtttc acaaacaagt agcaaaacgt gattgaaagg acgaaaagat
    31141 gctgaacatt ttaaacccct tgatcgacca actaaaaaag aaacatacat actttattct
    31201 tggcatagcc gtattattta caattattcg gttgtattta tatagtaaag caatctatgg
    31261 aacagatatg tcggcgacct atgatgatca gctgctgatt cactatgctc aaaatatttt
    31321 ggatggtaaa tggctagggg agtacacgac tacgacactt tcaaaaggga tttcctacag
    31381 cttgttttta gtacttgcac ataaactgca tctttcttat gcagttttat tcggcatgtt
    31441 cagtattctt gccagtatat tggttgcact agcgtttaaa ccaatcgtga agaacaagta
    31501 tcttctttta agtatctatt tttatttttt gttttctccg attagtttta cacatgaata
    31561 ttccactcga acatatcgta atgctctcgt gatcccgact gttgagatca ttatcgcttg
    31621 tttactagct atttattacc gcaaatataa ttccagcaaa aaattgctgc cgtggttttt
    31681 agggctagct gtttcttttc ctttcttttg gttcattcgc gaagattcca tctggcttct
    31741 tccttttact gtagtcgcgt taggcatcag tttcgttcag atcttgctag gacaagactt
    31801 ttctttcaaa gaagcaaaga agttaaaaga acgaccattt ctcctttcga aacaagaatg
    31861 gctgaaactt tcattgtttt tactccctct agtcggtttc tccatcgtct atcagtggat
    31921 cgaatataaa aacgagacaa catatggtat tgcagccatc aatgaccgtt cgagtggcga
    31981 atttggacgt ttgatgaaac agctgatccg aatagatgac gaaacaaact taaataaaga
    32041 aaacagtgag atatgggtct cgcatgctgc attaaataaa gctttagacg catctcctac
    32101 atttcatact gtttctactc gtattgacga attgtatacg actcatgcgt ggacccaagg
    32161 cggaaaagta aaagaattac caggagatat cattttttgg gcattgcgag atgtggtaag
    32221 cgaatctggt tattaccaaa acaatgcaaa agaaaccaat gatttttgga aaaaagtcaa
    32281 tcaagaatta gaagaagcct atcaaaaggg aactatcaaa aagaaaaaag aattctatct
    32341 gatgggatca ggggatggaa agacgatgaa tgatctgcca atcgtatttg attttctgaa
    32401 atcaggatat gcttatgcat ggcgatacaa agatttccat caagggggga attatagttt
    32461 tgggacgcaa gaacaagtcg aacaggcaca agaattattg aatcttccac taatggataa
    32521 ttggatcgat agcagtgatc cgagaacacc tgatttccag ttgacaaaaa cagcaaaagt
    32581 cgcgaatgtc atgataaaaa tttaccaagt tctggccatt cccgtgctga ttgcttcaat
    32641 agcagggata ttacttatga tactaggaac cgtatttgca aaagctgatc gtgcctatta
    32701 tagttcctct ttgattgtag tcatcggatt aatactgaca caattggttt ttcttttcgg
    32761 tgtctcgtgg ttttgttctt atgcgccaga aaaaaaggat tattttttaa gtgtctacac
    32821 tggcgcaggc gtgccattaa cgcaattcat cgcagtaaca agcatgctag tttttagtaa
    32881 attgaatctg aaaaaagctt tatcttccaa ataaaaaggg aactgtgaca aaagtcttgt
    32941 cgcagttcct ttttccgaat aaacggtgct caaaagcttg catctgcggt aataagctca
    33001 accaaacgta aaatatgagg aactattttt gtttggctgt tcttattact tgatgcaggg
    33061 cagctttttc acaacctctg atacacggtg ttccagaagt aacttcttcg gaaataagcc
    33121 gaaatttcac aaaaatttga aaagcaattt tcttaaattc cttcttattt cttgaagctg
    33181 cccacttctg tcacaacctc ctttgtgtaa aagaatcagt ttctattcga tttcttctat
    33241 cgtttcttgc aaacgctgtt catatttttt gtttccttta tataaatcac caatcgtcca
    33301 tgccaacagg agaaggacaa gaacaatgat tacataggcg atttgatcag ccaatgctag
    33361 ttgagctgag gtggcttgct cgccgaagaa actttcgatt tgacctggta atcctcgtaa
    33421 gttcaagtaa gtcagactaa tcacagagaa ccagccaaga agttttacaa caaatgaatt
    33481 tttgaatcgg ctccccatct ccgcttggct attggtcatc atcagtaaag gaatcatcga
    33541 gaatggcaat gcaaaagcca gaaaaacttg ggattcattc atcaagttat tcaaagcggt
    33601 atgttcttcg atcgttcctt ttgtacttgt aaacaaaaca caaatcaata caggaatcac
    33661 agaaagcaat cgtgtgacta gtcttcttag ccaaatcggg atacgcatat ggatgaatcc
    33721 ttccatgatg acttgaccgg tcaacgtacc agtaatagta gagttctggc cagaagcaag
    33781 aagtgctaca gcaaataaag tagacaagat accagatttt gctacagcaa tcaagatacc
    33841 attgctcata gctgatggat cagataaagc ttcatacaga ccaaaaaagg aaggatcttg
    33901 gacagaaccg gttttgaata cagcgacacc catgatcaat agcagtgcat tgactaaaaa
    33961 agccattgac aactggatat tagagtccca agtagaaaag cgtaccgctt gtgctacatc
    34021 ttcttcgtct tggtgatcga tcttccgagt ttgagaaact gctgaatgaa gatataagtt
    34081 atgcggcatg actgttgcac caataatccc taacgctcca gtcagcggag tttcaccacc
    34141 tatgacaggt gagtctgaga atgtatgact gttagggata aagccagcaa ataaactgtg
    34201 ccaatcaggg ttagacaagc caacttgata gacgaaaacg aataaaatga cgaaaatcaa
    34261 gcagacaacc aaagcttcga ttttacgaaa cccgactttt gtcagcaata aaaggacgaa
    34321 aacatctaac acagtgataa atacggcaat taccaatgga atatcaaaaa gtaagtagag
    34381 ggcgattgct gcaccaatga cttctgcgat gtctgttgcc ataatggcta attcagtcaa
    34441 gatccataaa atgacaccca atgtcttact tgtccgtgct cggattgctt gggccaaatc
    34501 catttgggtc acgattccta attttgctgc catatactgt aaaagcatag caattagact
    34561 agacatcaaa ataactgaca tcaataaata ttggaaattt tgtccaccag tgatcgaagt
    34621 ggaccagtta cctggatcca tataaccaac tgctactaat gcacctggtc cagagtaagc
    34681 aagaagtgtt ttaaaaaaac tttttccctt tggtacatcc actgttccat ttacttcagc
    34741 taaagataaa ccatttgtat gttcaataag tcgatgctta tgaaattgtt tgttggattg
    34801 attattcaag aaaaaaccac ctttcctatt tatctacgat tacattctac acctcagaaa
    34861 gaaaaaatta aagaaaaaga ttcggtatgc ctaatttttt ttcgtggcgt gtcttgctgg
    34921 ttaatgaaag aaattttgtt cttctctaaa aaaaccacta ttttttgcat gaaactaaag
    34981 aatacgcctt tcttttttca ataaacttta gtaaaataaa tcattgagag caattcggaa
    35041 atagaaagga gagatttata tggtatcaac aggtattgtc gtacttattg ctattattgc
    35101 tttgctaatc ggcgcagtag gtggcttttt cctagcgcgt aaatatatga aagactattt
    35161 agaaaaaaat cctcccgtta atgaggacat gttgcgatca atgatgatgt caatggggca
    35221 aaaaccatct gagaagaaaa ttcgccagat gatgcagcaa atgaagaacc aagggaaaaa
    35281 ataggttctg acccaaagac tttttgcggg ctgatttttt cagtccgttt tttatttcgt
    35341 aatttgttag actattcaga ctattcagca aaaaagacaa ggacagacaa tcctatgctc
    35401 ttgataaaga caaaggagga gtaaaatgtc gatttttaga aaattaggtt ggttttttcg
    35461 tcaggaaaag aaacattatt taattgggat tttctcccta ttcgcagtgg ccttggtaca
    35521 gttagttcct ccaaaagtga ttgggatcat cattgatgag atcgccgata agaatttatc
    35581 aataaagatc atttcttggt ggatcttact attgatcctt gcagctttct tacaatatct
    35641 ttttcgttat atctggcgga cgaatatttg gggaagtgca gctcggttgg agaaagaact
    35701 tcggcagcag ctattcaaac attttacaga aatggacaat ctcttttacc aaaaatatcg
    35761 gactggagat ttgatggctc atgcaacgaa tgatttgaat gcaatccaga atgtagcagg
    35821 agctggaatc ttgacctttg cagattcagt gattacgggc ggaacaacga tcattgcgat
    35881 gattttgttt attgattggc gcttaacact gattgcgctg attcctctgc ctttgctagc
    35941 cgttacttca cgagtgctgg ggtcaaaact ccacgatgct tttcgtgatt cgcaagaagc
    36001 tttttctagt atcaatgata agacacaaga aagtatcact gggatcaaag tcattaaaac
    36061 atttggacaa gaaaaagaag atctcgcgga ttttgaagaa aagattgaag atgcaattat
    36121 taaaaacaaa cgagtcaatt ttttagactc cttatttgat ccattcatta ccttgattat
    36181 cggtctgtct tatgttgcaa caattatttt aggtggaaag tatgtcttgg aaggcacgat
    36241 ctcgattggg cagatggtct catttattag ttatatcggt atgcttgttt ggccgatgtt
    36301 tgcgattggc cgattgttca acgtattgga aagaggaaat gcttcttatg atcgcgttaa
    36361 tgaacttttg catgaaaaga cgcatatcgt ggaacaactg ggtgcagtgc agaccccggc
    36421 aaaaggcgag ctgaatgtag ctatttcctc ttttaactat ccgaaagaag aatcaccagc
    36481 attagaacaa atcaaatttg cgatccaaga aggagaaaca ttaggtattg ttgggaaaac
    36541 tggtgcggga aaaacgacaa tcatcaaatt actgatgcgt gaatacgatg attatcaagg
    36601 gaaaatccaa tttggcggac gttcgatcaa agaatattca ttgaatgctt tattaggatc
    36661 aatcggttat gtgcctcagg atcacttcct gttttcgatg accattcgag ataatatccg
    36721 tttttctaat ccaaaacttt cagaagaaga agtagagcat gcggcttctt tagcatttat
    36781 caacaatgaa atcaaggaat tgccaaaagg ttatgatacc ttagttggag aacgtggagt
    36841 ctctttatct ggcggacaga aacaaaggat ttcgattgct cgagcattga tcaaaaatcc
    36901 tgaattgctg atcttagatg atgcactttc tgcagtagat gccaaaacag aagaagctat
    36961 cttgcataat ttaaaagaaa taagaaaaga gaaaacaacc atcattgcag ctcaccgttt
    37021 aagcagcgtg atgcatgcaa aagaaatcat tgttgtcgat caagggaaaa tcattgaacg
    37081 aggaacccac cacgagctgc ttgcattagg tggctggtat gaacgaatgt gggaaaaaca
    37141 gcaattagaa gcgaagatag aaggaggcga ggcctgatgg atgaaaatta tcaatcggaa
    37201 tggacaaaat cgattccact taaagaacag aagaagatca tcaaacgact gatgaagttc
    37261 gccaaacctt ttagaagaac gttcatcgtt gctatcttat ttgcgtttgc cctgtctgtg
    37321 atcaatgtcc tattgccaag gatcatccaa acttttatgg atgatcatct ggctaaacag
    37381 tcagctacga cacaagttat tttgtttttt gctggtgtgt acttgtttgg agtcatagtc
    37441 aaaagtatca tttggttttt ccaatggtat ttgtattcca tggcttcatt gaagacctat
    37501 cagtatgttc gggtaagatt atttgaaaag ctgcatacac taggtatgcg ttattttgac
    37561 cagacaccgg caggatcgac cgtttctcga gtgacgaatg acacagaaac gctatttgaa
    37621 ttttggtatg tctttttgat ggtattgact gggatctttg cagtcgtttc ttctttcgtt
    37681 gccatgtttc aaatcaatgg agaaattgcc ttgtggactt tggtgttctt gccgatttta
    37741 ggaatcgtca tctggtatta ccagaaattc agttctcgta tttaccgaaa tatgcgggaa
    37801 aaattaagtc agctgaacac gaaattgaat gaatcgattt ccggcatgcg tattatccag
    37861 cagtttcgcc aagaagctcg tttagctaaa gaatttgaac aagtgaacaa cgagtattta
    37921 gacacgcgct atgcgatgat caaaacgaat tcgattctgt taagtccgat catcaatttt
    37981 ctctatgcat tggcgattgc gttggcgttg actttgtttg ggatcgatgc gttgcattct
    38041 cccgtagaag ttggactgat ctatgcattt acgacctatg tccagggatt ttttaatcca
    38101 atgtctcaaa tgatggactt tttgagcacc tttacagatg ggatggttgc cggtagtcgt
    38161 attttgaaaa tcatggatac agaagaatat gcaccgcaac aaaatcctgg agcagatcaa
    38221 gcgattactt caggtaagat cgagtttcgc aatgtaagct tttcttatga tggagagcac
    38281 aatgtattga acaatatctc ttttgtcgct aatccgggtg agaccgttgc attagtgggg
    38341 cacaccggaa gcggaaaaag ctcgatcatc aacgtattga tgcggtttta cgaattttat
    38401 gaaggccaaa tcttgattga tgatcatgac attcgagaat atccaatgga agagttacgt
    38461 aagaaaatgg gattggtctt gcaagatgcc ttcttgtttt atggagatat tgcaggaaat
    38521 atccggatga tgaatccagc tatcacagac gaacagattc gccatgcagc tgagtttgtt
    38581 caagcaaaca agttcatcga tgaattacca aaaggatatc actcaaaagt gatcgaacac
    38641 ggtgccagct attctagtgg acaacgacag ctgatcactt ttgcgcgaac aatcgtgaca
    38701 gatcctaaaa tactagtatt ggatgaagca acagcaaata tcgatactga aaccgaagga
    38761 ttgatccaag aaggattggc aaaaatgcga caaggacgga caacgattgc gattgcccat
    38821 cggctgtcca cgattcggga tgcagaattg attttagttt tagacaaagg tcatatagta
    38881 gagcgtggga atcatgaaac acttctagcg caaaatggtt tgtatgcaga tatgtacaaa
    38941 ctgcaaagca gtggtgtgta aaaagaggtt gtgacagtag catagtagca ttttgtccta
    39001 agcgctagag tgaaaataaa acagagcttc ccagattctt catctgtgag cgttagtggc
    39061 gtagtcaccc gatttaaaaa agacgacgac agctagtcaa aagtgcctaa tagccactaa
    39121 gaaagcgttg acaaaagcgt ttgctttcga taatataaag aaaacgatac aacttggata
    39181 gtgattgcct gatgcaagct aaacctgatg agtctcccat ggttccatgg acggcttttt
    39241 gggtttttct ttttgttttg aatacagccc tatatatcat ggaaaggagc aaaacatgct
    39301 gattgagaaa gtactgaata acaacgtcgt aataaccagg gatgaaagaa atcaggaaat
    39361 gatcgtgatg ggaaaaggtt tggcattcaa aaagaaagtg ggtgacccga tttttgactc
    39421 atgcatcgac aaaaaatttc agttgacaaa tgacgggctt tcacaacagt tccaagaatt
    39481 ggcacaagcg attcctcttg agtacttaga aatttcttgt gaaatcattg aatatacaaa
    39541 agaggctcta caagtccagt tgaatgattc tgtgtatatt gcattgacgg atcatttgta
    39601 tacggctatc gaacgtcaca aaatgggaat atttgtacca aatgtattgc tgtatgatat
    39661 caaacaacta tttcctaaag agtatgccat cgggaaaaaa acagtgaaga aaatctcgga
    39721 taaataccac atcaagttat cagaagatga agccggattt atcgcattgc atttagtcaa
    39781 tgcacaaggc attcaaagcc aacaaaacaa tacctacctg tttactataa caatacagga
    39841 tattctaaat atcgtccgct attactataa gattacattt gatgaagatt cagtccattt
    39901 ttttcgattc gtcacacact tacgtttttt tctgacacgc gtcctagatg gagaaaaatc
    39961 agaagtggga gaagtttctg aggaattgtt tcaggttatt caaaaaaaat ataaggatac
    40021 gtttggttgc gttgagaaaa tagcagactt tttagccgag acgttcaact accagatgtc
    40081 cacggacgaa aaaatgtatt taacgatcca tactgcgcgt ttagtgcatg agaatcgttg
    40141 taaataaata aaaaaaggag gataaattaa caagaacgta tgaaataagg gtagtgacat
    40201 tcagttggct aaaccttcca ctaatatatt ggagggaata gaaatgggaa aataccaaga
    40261 attagcgaga aaaatcgtag aaaatgtcgg tgggaaggaa aatatcaatg gtttgacaca
    40321 ttgtatcaca aggcttcgtt tcaaattaaa aaacgaagaa aaagcaaatg atgagatctt
    40381 gaaaaatatg gacggtattg taacggtaat gcgagcggga gggcagtatc aagttgtcat
    40441 cgggaatcat gtgccagtcg tgtttgaaga ggttataaaa gcaggaaacc ttacttttga
    40501 tgaggctgtt tcaacagaaa aaatgagacc gtttgatatg cttattgatg gaatatcggg
    40561 ctgtttccaa ccattccttg ctatcttagc tgctggcggg atgattcgtg gactgacagc
    40621 attccttgtc ttcttaggcg cgtttgaccg cggttctggc acatttgtta tgtttgataa
    40681 tatcggtgat tctgtattcc aatttatgcc tgttattatc ggtttaacag ctgcccgtaa
    40741 atttaaagta aatgaattcg tagggatgtt gcttggcgca gcattaatga atcctagctt
    40801 gtcgctggaa gctttgagtg gtgcagcaga agcaccacta acgaccatat tttctggcac
    40861 tatttttgaa gcacctattt atcaaacagt attcggcatt ccctggattg cgcgtaacta
    40921 cgcttcttct gtcattccca ttatctttat tgtgttgtta gctagccaaa ttcagaaacc
    40981 aattaaaaag ttagtacctg agatgatcgc gaatttcttc gttccattct tcaccgttct
    41041 tattacaatg cctttaggtt ttttactcgt tggaccagta ttcacattcg caactgatat
    41101 tttaatggct ggatttgaaa cacttttagc actttcgcca gttatttatg gagcaatcgt
    41161 aggcttcttc tggcaaattc tggtgatgtt tggtctccat tgggcaatcg taccaatggg
    41221 attgatgcaa ttttctgtga atggttggca aaatattatg acacctgttg cagtagtgtc
    41281 ttttggacaa actgcagcac ttaccgcact ctactttaag cttagaaatc caaaagacaa
    41341 agcaattgca ataccagcca ttgtttctgg tattgtgggg attacagagc cagctattta
    41401 tgggtttaca ttaccacgta aaaaaatatt tatttttact tgtgtcggtg gtgcgttagg
    41461 gggcgcgtat agtgggttaa tgaatttaac ttcttggaat caaggtggac taggcatctt
    41521 tacaattccc aactatatta gaccagatgg tgatttaaca gatgtgatta atgtattgat
    41581 tgggatcgcc attgcgatgg tggtatcctt tgcgctgact tttttctttt ggaaggagga
    41641 agcaggtgaa acagatgaca gacagaaaag atcaggtaaa gaaattgtaa aaacaccgat
    41701 acaaggacaa atcgctccac tgaaagcagc aaaggatgca gcttttgcac aaggaacact
    41761 aggtcgagga atcttgatct accctgaaaa aggagaagta cgtgcccctt ttgacggaac
    41821 agtcatgacc ctgttcccca cgaaacatgc aatcggaatg gtttctgaaa caggtctgga
    41881 attgctgatt catgtcggat tggatactgt tcagttggaa gggaaatatt ttgaaagctt
    41941 ggtgcagcaa ggagaaagag tgaaacaagg cgatctgttg ctccgcttcg acaaaaagaa
    42001 aatcgaaaag gaaggataca gtttagaaac acctgtaatc gtcaccaatt acatggatta
    42061 tttggatatt ttggaaaatc aaggggagac ggtcgggcca gacgatgcac ttatcaccgc
    42121 actgacctga acggttaggt gaaagaatgg aatagactta actattcttt ttagtccact
    42181 tctttatttt caaaattgaa aggctctttc atgatggctg agctgatagg gcgtttatca
    42241 aatttttgtc ctacagaaat tagatggact aaattctgtt gataattttc tgcaaaaaca
    42301 caactatata acacgtctag aagataacaa atcgatgtat tgatcgtaaa attaccaatt
    42361 tttgaataca gtcgttcgcg tgtcgtaagt cgcaaagcgg ctgtactcat tgaggatagc
    42421 gttgaatcac cgatactggt caacgctaaa attggaacat gattttgttt caatatttct
    42481 gcggtacgaa ggatcacatt gttttcaccc gtataagaaa tcagaatccc gcacatatca
    42541 ctcgtgcaat tgtacgcttc atagaacgat tcaccaaaag tggtgacaat cgtgacatcc
    42601 attttgatgc gcttcatttt cagcatgaaa tcttgagaaa tcaaagtatt cgagttactg
    42661 gcgaaaatca cgattttttt tgcttgaagc attagttgtt tggctttttg cagttggtca
    42721 tgatgaatga gagaaagtgt atcttgaatc gtcatctgtt ctaaagaagc cattttattt
    42781 gcgatcgtca taataccgtc tgtggtggaa aaaggaagat tcgcatctac gtcttgaaaa
    42841 ttcccttcaa gataggctgt ttcagctaaa aaagcattac gaaaactgac ccagccatca
    42901 aaacccattt tttttgctac acggatgagt gtggacgggt ggacataaca tcgctcagca
    42961 atctcttgga tggtcatttc gccaagtgct ggagaatcgc ttaagagaaa ctgaatcact
    43021 tcattttctg aaggagaaaa ggagatttct ttgatttttt cacgtaataa catgtagata
    43081 ccttcttcta gtttttttac gtaaattata acttttttga aaatgatttg taaacggatt
    43141 tatgttatat agcttaataa agtcattttt tgacaagata tttacaaaaa tccagtagaa
    43201 aacactaact tttgtaaatg ttactggaaa gaaacgaatt tctattgttt gttttgttta
    43261 caaaaaagat aataaaagtg taaaaagcaa aggagtgaga acatggcaaa aggaatcaaa
    43321 atcgctacga ttggtggagg cagcagttac acccccgagt tgatggaagg atttatcaaa
    43381 agatatgagg aattaccgat acgagaaatc tggctcgtag atgtagaaga aggaaaagaa
    43441 aagcttgaga tcgtcagtca gatgtctcag cgtatgtggg atgcttctcc gtatgaagtc
    43501 aagatctatg caactttgga tcgggaagaa gcattgaaag atgcggattt tgttacgact
    43561 cagtttcgtg tcggtcaatt agatgcacga atcaaagacg agcggatccc tagttattat
    43621 gggatgattg ggcaagaaac aaatggtgct ggcgggatat tcaaagcttt tcgtaccgtt
    43681 ccagtggttt tggcaatcgt tgaagacatg aagcgtttat gtccaaatgc ttggctgatc
    43741 aatttcgcga acccaagcgg gatggtgaca gaagcagtta tcagatatgg caaatgggat
    43801 aaagtgatcg gattatgcaa tgtgccagta atggcgacga tgacagaacc agcaatgctt
    43861 ggcaagaaaa aagaagagct gatctacaag tttgccggtc taaatcactt ccattggcac
    43921 aaagtagcag ataataaagg aaatgaccgc acagcagatt tgattgatcg tttatacgat
    43981 gaagacaatg gattgccgaa aaatatcttt gacatcccgt ttttcaaaga acaattaaaa
    44041 caaatgaaca tgatcccttg tggctaccac cgctattact accgtgaaga agaaatgttg
    44101 gaacatgctt tagaagaata tcaaacgatt ggtacaagag cgcaacaagt gaaagaaaca
    44161 gaagcagagc tgtttgaatt atacaaagat ccagaattgg atcataaacc tgaacaattg
    44221 caaaaacgag gtggtgctta ttattcagat gctgcctgtg aaacgattgc ttcgatctat
    44281 ggaaataaag aaacacagat cgtggtgtct acaaagaatg atggagctgt tcctgatctg
    44341 ccggcagatt gtgtagtaga agtcactgcc tatgttggcg cacaaggcgc acgaaatgta
    44401 gcgtttggtt cccttcctgc tgctgaaaga ggctggttgc aagtaatgaa gaatatggaa
    44461 ttgctgacga tcgaagcagc cgtgactggt gattatggaa cagctttaca agcgtttacg
    44521 atcaatccgc ttatacgatc aggaaagaca gcaaaacgga tcatggatga gttgtttatt
    44581 gcacatcagc agtatttacc gcaattcaag gaaacaatca gccggttaaa agcagaagga
    44641 atcgaagtcc aagatgaact ggcaagagaa ttgtcaagca atacacatgt aatggaggaa
    44701 gtatgatggg attcagaaaa gattttttat ggggcggtgc tacagcagcc aatcaatgcg
    44761 agggtggtta tgatgaaggc ggacgtgggt tagcgaacgt agatgttgtg ccaatcggag
    44821 aagaccgttt tcctgtcatt actggaaaaa agaaaatgtt tgaatttgat aaagatcatt
    44881 tttatccagc aaaaattgcg atcgatatgt atcatcatta taaggaagat attgctttgt
    44941 ttgcagaaat ggggttcaag acttatcgga tgtccattgc ttggagtcgt atttttccaa
    45001 tgggcgatga aaatgagcca aatgaatctg gtttgaaatt ttatgaggat gtctttaaag
    45061 aatgtcaaaa gtacgggatc gagccgcttg tgacgattac acattttgat tgtccgatgc
    45121 atttgatcaa agaatatggt gcgtggcgtt ctagagaact cgttggtttt tatgaaaatc
    45181 tgtgccgagt catcttcaat cgctataaag gacttgtcaa atattggttg acattcaatg
    45241 agatcaatat gatccttcat gcaccattca tgggcgcagg gctgtatttt gaagaaggag
    45301 aaaatgaaga acaaatcaaa tatcaagcgg cacatcatga gttggttgca agtgccatcg
    45361 caacgaagat tgctcatgaa gtagatccgg agaacaaagt aggctgtatg ctggcagcag
    45421 gagcatatta tccatacact tgcaatcctg aagatgtttg ggcttctaga aaatcagatc
    45481 gagaaaatta tttcttcatt gatgtccagt cacgaggaga atatcccgct tatgcattga
    45541 aagaaatgga acgaaatggc attcagatca aaatggaacc tggggatgcc gcattgctga
    45601 aagaacatac tgttgatttt atctcctttt cttattattc ttctcgagtt tcgactactg
    45661 acaacgaact cttggaacag actgcaggaa atatctttgc ttctgtcaaa aatccatatc
    45721 tggaagcaag tgaatggggt tggcaaattg atccattagg cttgagaata acgatgaatg
    45781 atatttatga tcgttatcaa aaaccactat ttattgtaga aaacggctta ggtgcagtcg
    45841 atacgcccga tgagaatggt tatgtggaag atgactatcg aatcgactat ctggcagcac
    45901 atatccaggc aatgaaagat acagtagaat tagatggagt cgatctatta ggctatacga
    45961 cttggggatg tattgattta gtatcagctg gtacaggtga gatgaagaaa aggtacggat
    46021 tcatttatgt cgatcgtgac aacgaaggaa atggcacatt agcccgttcg aagaagaaat
    46081 cattcaactg gtataaaaaa gtaattgatt caaatggaga aaatctttcg aatgattgat
    46141 caatgatttg taaaagtcta ttgtttttca gcggattttt cgagtataat aaagctattc
    46201 gagaaacgca agcagaacaa tagacttttt ttcgcattgg ctgtaaagta tgcttacttg
    46261 attaagtaaa ggagaatcta catatgtatg atgtaatcgt tattggcgca ggtcctgctg
    46321 ggatgactgc tgctttatat gcttcacgtt caaacttatc cgtattgatg atcgaacaag
    46381 gcgcccctgg cggccaaatg aacaatacgg cagaaatcga aaactatcct ggtttcgatt
    46441 caatcatggg tcctgatcta gcttataaga tgtatgaagg tgtttcaaga tttgggacag
    46501 aaaatgctta tggaatcgtg caagatatca aggatcacgg cagccacaaa gaagttattt
    46561 gtgaagataa aacttacgaa ggaaaaacag tcattatcgc aacaggctgt atccaccgta
    46621 aattaggcgt acctggcgag gaagaatttg ctggacgtgg cgtttcttac tgtgcagttt
    46681 gtgatggtgc gtttttccgt aacaaacgtc tagtagtgat cggaggagga gactcagcag
    46741 tagaagaagc catctatttg acacaatttg cttctgaagt agtcatcgtc caccgtagag
    46801 atgaattacg tgcacaaaag atcatccaag accgtgcatt tgcgaatgaa aaaatttcct
    46861 ttatgtggga tacagtcgtt gacgaaatcg ttgggaatga aatggtagtg acaggtgtga
    46921 aagcacgtaa tgtcaaaacc ggcaatgagt ttgatttggc agcagacgga gtattcatct
    46981 atgttggact ggatccatta actgcaccat ttagagaagc agggttgacg aacgaagctg
    47041 gctggattcc aacagacaac gaaatgaaga cgaatatacc aggcgttttt gccatcggag
    47101 atgttcgtga aaaagatttg cgacaaatca ctactgctgt tggtgatggt gggatcgctg
    47161 gacaacaagt gtataaatac ttggaatctt tagaagaaac aactgcataa gtttaaaaag
    47221 agtggaagaa cggtttcaat tgttctttta ctcttttttt tcgcgtgaaa tctactgaat
    47281 ccgatttatg cgaatacttg caaccgtgct tgataaaaga atcctttctt gatttaagcg
    47341 ttttttagac ctcgtacttt catatctaat aagtgaatgc tatacttatt aagaaccata
    47401 tttcagaaag aggtgttatt ttcatgtctt gggaacaagt gtatgaacaa tgggtacatg
    47461 aagaaaattt agaagaaaac ttaaaaaaac aattaattga tctgggtgaa gatcctgaaa
    47521 aacttgaaga tgctttttat gcaccgttgg aattcggtac tgcaggcatg cggggaatct
    47581 taggacctgg gatcaatcga atgaacatct atacggtaag acaagcaaca gaaggacttg
    47641 cacgtttcat ggatacacaa ggtgaagaaa caaaacgccg aggtgtcgct atcgcttatg
    47701 actcacgcca tcaatcacca gaatttgcca tggaagcagc caaaacatta gcacatcaca
    47761 atatcccttc ttatgtattc gaaagtttac gtccaacacc agagctttct tttgcagtcc
    47821 gtcatttgaa gacgtttgcg ggaatcatgg taactgcatc ccacaatcca gcagcttaca
    47881 acggatataa agtctacgga gaagatgggg gacaaatgcc tcctgcagac gcagatgcat
    47941 tgacgaaata tgtccgtgaa gtcagcaatc cgttaaaagt tgaagtatta tctgacgacg
    48001 aagctgaaca tagcggattg atcacgatca tcggagaaga agtggatgcc gcttatctag
    48061 aagaaatcaa agcagtaacg attgatcatg aattggtgga aacaatgggt aaagatttga
    48121 aacttgtgta cacaccactt cacggaacag gaaaaatgtt gggcgaacgt gcgttgaaac
    48181 aagctggatt cgaacaattc gtactagttc cagaacaagc tgtcgcagac ccggatttca
    48241 ctacagtcaa atcaccgaat ccagaagaac actctgcttt cgagtatgcg atgcgacttg
    48301 gcgagaaaga aggcgctgac ttactgattg caacagatcc tgatgcagac cgtttaggcg
    48361 cagccgttcg tttgccaaat ggctcctatg aagtattgac agggaaccaa atcggagccc
    48421 tgtttgctca atatattttg gaagcacacc aatcgcgagg cactttacct gaaaatgcag
    48481 cggtattgaa atcaatcgtt tctagcgaat tgcctacagc aattgcggaa cactatgggg
    48541 ctaccatgtt caatgtattg acaggattca aattcatcgc tgaaaaaatt caacaatttg
    48601 aagaagatca ttcccatact tttatgttcg gattcgaaga aagttacggt tatttagtta
    48661 aacctttcgt tcgcgacaaa gacgcgattc aagcattgct cttattagca gaagtagcag
    48721 cttactataa aaaacaaggc aaaacgttgt atgacggctt gcaaacgatt tttgaaacat
    48781 atggctacta cgcagaaaaa acgatttctg tgacaatgag cggacaagaa ggttctgcaa
    48841 aaatctctgc tttgatggaa aaattccgtg aagaagcacc gacagaattt gccggagcaa
    48901 aagtcatcca aacagaagac ttcaaagagt tgacgagaac agaccgtgaa ggaaacgtag
    48961 aaaaactaac gacaccgcca tctgacgtat tgaagtatac gctggaagaa aatggctgga
    49021 tcgctatccg tccttcagga actgagccga aaatcaaatt ttatatcggt gtaaaaggaa
    49081 actcttcaga agacgcagct gaaaaagtag ccgcttatga agcgattatc aaaaaaatga
    49141 cagaagaata aaaaaacttg agactgatgg aaaaagtggt aaactttaga agtcagtctt
    49201 ttttcaagtt ggaggtgaat ggattgccag acacgcaaaa aacaaaagta gagaaagtca
    49261 gccaactatt caaaatgttg agtgacccca ctcgtctcaa aattctgctg tatctgaaag
    49321 acggggaaca aaatgtgaca gcaatcaccc aagcagtaga aatggaacaa tctgctgtat
    49381 cgcatcaact gcgtttatta agagaaaacc atgtcgtcaa gtcccatcgt gagggaaaag
    49441 cgattttgta tagtcttgat gattctcacg tactggatat tttgaaccag acgctcaaac
    49501 atgtggaaca tcaataacga taggtgcaaa tagagacaaa ctggactgta tcaacgaatc
    49561 ttcttcgctg acacagtcca gtttttttaa gaaaaagaca agaaaaactg ttagtctgtt
    49621 tcttcggtgg tttcagttcc ataataacta tgatcttcta ggtctaaagc attcaaaata
    49681 agtgaagctg tttcttcgat agataaagaa gcgacattga ttactacgca gcccaatttt
    49741 tcataaagat cattcgcaaa atcgagttca gctcgtattt tttcgatatc ggaataagca
    49801 gtatcaggat ttaatccgta agagcgcatc cgttctttac ggatattgtt taaaatatct
    49861 gggttattcg tcagtcccac gattttttta ggatcgatct cccaaagctg tttgggaata
    49921 tgtgcttgtg ggatcaaagg tagattggca acctttaaat ttttgttagc taaaaacaag
    49981 ctcaaaggcg ttttggaagt tctggatacg cctagcaaaa cgacatctgc ttctagaaac
    50041 ccacgaggat ctttcccgtc atcgtatttt acagcaaatt ccattgcttt gatccgtttg
    50101 aaatagttct cattcaataa atgaagggcg ccaggttgcc gaatgggctt gataccagtt
    50161 aagcgctcga tttctgatat cggcggagtc atcacatcaa aactaaataa ttgatgttct
    50221 tcacaaaaag aacgcgtcat ctcgatcaat tcttgattga tcaatgtgtg caggacaagg
    50281 gctttttctt ttagtgcatc ttgcagtgcc tgcatcaatg ttttctcatc tgtcacaaat
    50341 gttctgcgga ataaattgaa ctcaacggta ggatattggg ccatagtggc ttgcgctaat
    50401 tttgtcgcag tttctccagc agagtcagag atgacaaaaa aagtaacgat ttctgtagaa
    50461 tcggaagaca tggataaaac ctcacttgca ttttttttat gtttattata ccatactcta
    50521 gaatgtgtac ttcgtaatca ttttgatttg gaggaataag tcatgaaaaa acagacattg
    50581 attgaacaat cactagaaac attgaaaaat aacggtttta aatatactaa aaaaagagaa
    50641 gcattgttaa cttatttagt gaagcgcaat cgctacgtat ccgctaaaga agtttttgac
    50701 tatatgaatc aggaattcaa aggagtaagt tacgatacga tttatcgaaa tctccatgat
    50761 tttgcagaaa tcgatttact ggaagaaacc gatttaaatg gagagatgaa gtttcgtttt
    50821 cattgctgtc aaggggaaat cggccatcac catcacttta tctgtacggt gtgcggaaca
    50881 acgaaagaaa tccatatgtg tccaatgaat tatttcgaag aacagctcgg tggatgtacg
    50941 atcgaagggc atagattcga gattttcgga agatgtgaaa attgtcaata aggatttaaa
    51001 taaaataaca tttgataatt ttaaaaaaaa gcaagatttc cttgacggtc aaaacagcat
    51061 tagatataat atttacagga cagtcttgtt ttttgagata tatttcaata acaattacgg
    51121 ttacttttta agctcggagg gagggaatta acatgtcaaa aacagtcgtt cgcaaaaacg
    51181 aatcacttga cgatgctctt cgtcgcttca aacgttccgt gtcaaaagcg ggtactttac
    51241 aagaatctcg taaacgtgaa ttctacgaaa aaccaagtgt aagacgcaag aaaaaatctg
    51301 aagcagctag aaaacgcaaa aaattctagt tctgtgatga attggagttg gtagtgtgtc
    51361 actactaagt agattaaacg atgacatgaa aacagcgatg aaagcgaaag ataaggaatc
    51421 tttacaagtc atccgaatga tcaagtcatc tatacaaaac gagcagatta aagaaggtca
    51481 cgacttgaca gaagaagaag aattaacggt gttgtctcgc gaaatgaaac agcgacgtga
    51541 ttctttgcat gagtttgaag aagcaggacg tgacgattta gctgaaaaag taaaaagtga
    51601 aattgtgata gtcgaaaaat acatgccgga acaactttcc gacgaagaaa ttcgacaact
    51661 tgttcaagaa gcaatcacac aaactggtgc ttcatcaatg aaagaatttg gcaaagtcat
    51721 gggtgcgatc atgcctaaag tcaaaggaaa agcagatgga aaccaagtaa atgccattgt
    51781 gaaagaacta ttacaatctt aattttatca tttaaactgc ggacaatcat tgtccgcagt
    51841 ttttttgtgc gcgtaaaaaa gagaacaaaa aaatagctag acgaaagaat aggattcttt
    51901 catctagctg gttttttcct gtttaatatt tcttatgtta aattgtgttt gatttggtta
    51961 ttcttctggt agttcatttg cttcttgttt ataccctgat aggcgatagg cgtaataaaa
    52021 cagtaggctg ccagcgtaac caagtaacgt tgggaccatc cagccaagtc ctaatgcagc
    52081 aaaaggaacg tgatgatgat aaaattcgag catgcttgct acaactcttt gttgactcac
    52141 taaagcaggc gaatttgcca gcatatccaa tacggcagga acagcagcaa acaacatcgt
    52201 tacttgatag acaaatggtg tcttttggaa aaattttgct gttaaggaaa gcaagatcaa
    52261 cgcaagcgac aatggataca aaagcatcaa tactggtaaa gaccattgga tgatattgtc
    52321 taaaccagca tttgcaacga caaaagagac gaaagtcgtt aaccgcagcc atgtcatata
    52381 actgacttta gggaacagtt tatggaaatc ttgcgcaaaa gaaacaacga gtcccatagc
    52441 ggtagtgaag acacctaatg tgaccatcac tcctaagaag ctagcgccga agttacctaa
    52501 ataaaaatta gtgatctgag aaagtgcagt tccgccattt tctgataaag acatcttatt
    52561 caaactcatc gcaccgagaa gaacaagacc aaaatagatc atgacttcta gcgcaacgct
    52621 caggctacca gcttttgctg ttaattctgt gactttttta tctttgaaac caaggtcacg
    52681 gactgcatgg acaaaagtga cacttaaggc aagcaaggct actgcatcaa ccgtgttata
    52741 accttctagg acaccatttg ttaaagcgtt tgtttggtaa gtatctgcag cagattgatt
    52801 tagatttccc attgggtgga ataaagaaac gacaaaaatg attgctaaca atgcaagaaa
    52861 caaggagttt agatactttc cgacgtattt gaccaaccgt gtgggatgga cagtaaggaa
    52921 ataagcaagt aaaaagaaaa gagcagagaa taaaaacata cctaatgaat tatatttttc
    52981 aggcaaaaat ggtttagcag ccatttcaaa agcagtagca gctgtccgtg gtgtaccgaa
    53041 aaatggtccg atcgtcaaat gaacaaggat taagaacaag gcagcatacc attttccgac
    53101 aggtttagct aagtcataca gaccatcact ttttgtcact actacagcta agatagctag
    53161 taatgggaaa agagcgcccg agatggcaaa tcctacgcca gcactgaccc agtttgcgcc
    53221 agccatttga cctaagtgga caggaaagat tagattacct gacccgaaga acatcccgaa
    53281 gataagtgaa ctgaccatca atagttgttt ccatgaataa gtttttgttt cttccataaa
    53341 tttttcctcc aataattatc attttgattg acgatataaa cgttgcagca attagtaatg
    53401 ccactaatat cagattccat gaaaaccacc accttaaaat ataaaaaaag cccttttcca
    53461 cttgggaaaa gggctctaga ttctagaacg gtaccacctt ttttcgctta aaaaagcttc
    53521 ttcattcacg gacgcttttt gataaagtta tccgctagcc tgataatgga ggcagccaca
    53581 atgatctacg ttttcgacat tgactcggaa atgatgttcg tctattcgat ttattgtcat
    53641 ttctcactta catgactcac tgggaataaa tcgttgaata gcctactgtt ttcctcgacg
    53701 ctttgctgta tgtttatttg ttgacgtaat aatacacctg ttttttttga aatgcaagaa
    53761 tattttaact attttgtttt ctttttttga aacaagaaaa atacctagag aatacctgct
    53821 gaatgaaacg gaatattttg ttctccactt tcatataact tacattctca gcttcttttt
    53881 atcaaaacga gacctttagc gaatggaaac ggctattttt taacgtttct tggtacgtat
    53941 ggttaaacga ctcttttaca accttttctt atttgctata tagtttcttc tgagtatggt
    54001 aaaataggaa agaatgaatc gaaaaaaagg ggatgtctat ttttgacgga agagtctagt
    54061 tctttagaga ttagattgac agctgctgat gatgtcagca tgcttttagg tgcacacgac
    54121 aagcatataa aactgatcga ggaaacaacg gaaacaacca tccatacacg tggagaaatc
    54181 attcagatca ttggtgagca atcccagatt tccttggctg cctcagtcat tcggacatta
    54241 caggaattga tcaaacgagg aatccacgta agtacgccag atgttgtgac ggcattgaag
    54301 atggggcaaa aaggtacatt agattatttt gttgagatgt atgaggaaga gatcgtcaaa
    54361 gaccgtaatg gaaaacctat acgggtaaaa aacagcggtc aaaagaaata cgttgaatcg
    54421 gtagccaaac atgacatcgt atttggtgta gggccagccg gaacagggaa aacgtttctt
    54481 gccgtagtat tagcaattgc tgccctaaaa aaaggcgaag tgcaaaaaat cattttgacg
    54541 cggcccgctg tggaggcagg ggaaaaccta ggctttctac ccggggatct gaaagaaaaa
    54601 gtggatcctt atctgcggcc tgtttatgat gttttatacc aaatttttgg attggatcat
    54661 acgaaccgat tgatggaacg aggcgtgatc gaaatcgcac ctttagctta catgcggggg
    54721 cggacattgg atgatgcatt cgttatcttg gacgaagcac aaaacacgac agtcgctcag
    54781 atgaaaatgt tcttgacccg tctcggttat caatcaaaaa tgattgtcaa tggggataca
    54841 agtcagatag acttgcctcg tgggacgaca agtggtcttg ttcatgcaga acgaacatta
    54901 aagcaaatca aaaaaatcga ttttgttaat tttgaagcaa gtgacgttgt tcggcaccct
    54961 gtagttgccg aaatcatcaa agcttatgaa aaggcggatc ttcatcaaga ataagctttg
    55021 cttaggagga taagcacatg ttgaataaaa cactgcagaa actacaaaaa aaactcggaa
    55081 aggcagcatt gcctttcctt ctgttcttgt tttttatcat tgtctgcggc gttacattta
    55141 gtagtgtcaa acaaaaggcc aatgatttca gagaaggcca agtagcagaa gagagtatcc
    55201 gtgcgaataa aacgattgag aacacggaag aaaccgaaca aagaagaaaa ctggcagcag
    55261 aagcagtgac tccagaatat acttatcaaa aagatctggc agatgaccag aacaatcgga
    55321 tcaagcaatt attcgaattg atcgataaga cgaatgatac catcaacaaa tcttataatg
    55381 acaaggtaga taaggcgaag gaagatgaaa atatcccgaa acctactaca gaagagcgga
    55441 ttgctacact gaagaaaaat tttgaaaacg tgaatgcaga aaacgttgcg ttttaccaaa
    55501 aactgccgaa caatttttat tcgacgatat ttgaaatgac tgaaacggaa attcacacgg
    55561 ttagggatga aagtttgaag ctcattgacg aacagatgag taaacaagtt cgtgaaagcg
    55621 aattggaagc ttttaaacaa gaagcagaag atcagattca atatttgaat gtcacaacag
    55681 agcagcaaca aatgattcgc tacttagtgg atcaaggcat tgtagttaat gatgtattga
    55741 atgagaaaaa gacagaagaa ttaaaacaat ctgcacgaga agctgtacaa ccagtgatga
    55801 tcttccaagg agaaattatt gttcgcgaag gaaatcaaat tgatgcttca gcgatgaaaa
    55861 aattggaatt actaggattg acgaatcaaa cgacttctat tttcccactc attgccatgg
    55921 ttttagctgt tttgcttcaa atcggtgtac tgatttataa ttcacttcaa ttccaaaatg
    55981 caggagaaag aacaaaatac gtacttttct acgtgacggc aatgtcagta agcgtcgtac
    56041 taatgaaatt tttccaactc ttccaaacag aacaagctgc ttatattccg ctgttttacc
    56101 ccgcggcttt tgctccactt gttttaagct ttttcttgaa tcgaagagca gggatcatgg
    56161 ctggtatttt tcaagcagta tccgcacttt tcatttttta tgattcgatt ggcacgaact
    56221 ttctgacagt tattttgatg tcctatgtat tttctggtct catggcaacg atcgtcagac
    56281 gcaaacggat ctcagaacaa gggttatccg ctgctatgtg ggtcattatt tttcctgtga
    56341 tgatggatgt cattttgatt atctaccaag gaatgagctt tggggatgca acgacttggt
    56401 taacgctagt atgcggattc acaggtgcac tgttctcatt cttgctgacg ataggtctgc
    56461 acccctatat tgaattgatg gtcaatgatg atagtgtgat cgtattaaat gaactcagca
    56521 atcctaatca tcctttattg aaacagttgc tggaagaagc accaggcacg tatcaccata
    56581 gcatgatggt agccaatcta agtgctaatg ctgtagcaga aatcggtgga cgttctttac
    56641 taactcgagt agcttgctat tatcatgata tcggcaagat caaacacgcc agctttttcg
    56701 ttgagaactt gccttcagga gcggaaaatc cgcacaattt cttattgcca gaagacagta
    56761 aacatattat ctttggacat gtgacagatg gtgccaaaat attggaagat tataatatgc
    56821 cgcaaatggt gatcgatatt tgcagacagc atcatggaac cacgctgatg cgttatttct
    56881 acgttaaggc aaaggaacgc aacccggaag tcacggaaga gcaattccgt tatcctggac
    56941 caaaacctca aagccgtgaa gcaggaatcg tcaatatagc tgacagttgt gaagcggcag
    57001 tacgagcaat ggaccatcca acgagcgaaa aaatcgaaag ttttgtccat aatcttattg
    57061 aagagcgtat ttccgatgga caattggacg acagtggatt gacgttaaaa gaaatccgta
    57121 aagtagaaaa atcattgatc agcggtttaa gcagtacctt ccattctcgg atcaaatatc
    57181 ctaaaatgaa atcggaagtt gagaagataa aagaagaaca agaagaatag aaagaagcga
    57241 tgtataatgg atattacttt catggatgaa acaaaccaag tctcagaaga gaaaatgaaa
    57301 gaaatcgacg acttgctgca atttgcagca tcatatttag agttgccaga agaaacagaa
    57361 atgtctgtta ctttcatgga caatgcagcg atccaagtaa tcaatcgtga ttaccgtgga
    57421 aaagatgcac cgacagacgt catcagtttt gccttggaag aagagggcga agacgaaatc
    57481 ccagtgattt ttgaagatgg agagaatcca ttgcctcgtg tactgggaga catcatgatc
    57541 tctactgaac gtgctgcaga gcaagcagaa gcttacggcc attcgtatga tcgggaactt
    57601 ggctttttag cggttcatgg attcttgcat atcaacgggt atgaccatat gacaccagag
    57661 gatgagaaag aaatgtttgg tttacagaaa gagatcttag atgcctatgg acttaaaaga
    57721 taaaaacgta gagaaaaaca aacatttcct gatgtccgtg gaatttgccg tccaaggagt
    57781 caaaaccgtt tttgaggaag aacgcaacat gaggaaacat gttgcgttcg gaatcctcgc
    57841 tttgtttatg ggcgtgattt tccagcttga tcggatagaa tggttatggc tgcttttagc
    57901 tgtttttctc gtatggatag tagagatcat caatactgtt tttgaaaatg tcgtggacat
    57961 gtttacggat tttcattttc atccgattgg gaaaaaaatc aaagatatgg cagctggagc
    58021 agttttagtg accgcttgtt tttccgtcat cgttgggttg attttatttg tccctaaaat
    58081 atatcatttg ttgtttaatt aaaaaggaga acgtatatgc cagaacataa atcagggttt
    58141 gtcgcaatcg tcggccgccc gaatgtagga aaatccacat tattgaatcg aatcgtgggt
    58201 caaaaaattg ccatcatgag tgataaggcg cagacaacta gaaataaaat ccaaggagta
    58261 tatactacac cagaagctca gttgattttt attgacacac caggaatcca taaaccaaag
    58321 catcgtttag gagattttat ggtagaagca gcttacagtg cgttgaaaga agtggacgcg
    58381 gtcttattta tgatcagcgc tgatcaaaaa cgcggtcggg gagacgattt tattattgaa
    58441 cgtctaaaaa acgtgcattc tcctgtttat ctgattatca ataaaatcga taaaatccat
    58501 ccagacgagt tgttgggaat catcgaagat tattcaacgc agatgccgtt tgcacaagtg
    58561 attccaattt ctgctacaga aggaaacaac gtcgaacgtt tgatggatgt attagtcagt
    58621 gaaatgccag agggcccaca atattttcca gatgatcaag tgactgatca tcctgaatac
    58681 ttcatcgttt ctgaattgat ccgtgagaaa gtcttgtttt taacacgaga cgaagtgcct
    58741 cattctgtcg cagtcgttgt tgattcgatg aagcgaaacg agaatgataa aatccatatc
    58801 caggctacga ttattgtcga aagagatagc caaaaaggga tcattatcgg caaaggcgga
    58861 aaaatgctga agcaagtagg aacgaaagcg agaaaagata tcgaaaatct tttaggagac
    58921 aaagtctttc tagaactttg ggtcaaagtt caaaaagact ggcgagacaa aaaagtctat
    58981 ctgcaagact tcggctaccg aaaagacgaa tattgatatt ctgagcttct tgtaagttag
    59041 gtatagaaat aaactggata aaaatccgcg tgttgagaaa agctgcggaa gatcgcaaca
    59101 taaatgatct ggatcggcag aatctgcttt tccagattta ttttttagga gggagaatat
    59161 gagccagctt gcagaatcaa aaggcttgat tttatctagc cgtaattaca aagaaaaaga
    59221 taaattagtc aaaatcttta cggaatcttc tggcaaaatg atgttttata tcaaagggat
    59281 ccatcggcaa aatcagccct tagctccggc tttgctccct tttactgaag cagtttatat
    59341 cgggaatttt cgaagtgaag gtttgtcatt tttaagcagt gtcaaagatg tccacgcgtt
    59401 tcgacacatc caagaagaca tctttttgag cggctatggc acatatttat tgaatctagt
    59461 agatgcggca atcgaagatc atcagtacga cccgcatttg ttccagttta cgcaacaagc
    59521 actgcaactg atggaccaag gagatgatgc agaaatcatc acgaatattt ttgaagtcca
    59581 aatactgcaa cgcttcggaa ttgcaccaat ctggacacac tgcgtcgtat gtggggaaac
    59641 aaaaggaaaa tttgactatt cttccaaata tggtggtgtg atatgcgaaa gacactggtc
    59701 gatggatgat caccgttatc atgcagatcc tcgagctgtt tatttcgttc ggatgttttc
    59761 agctatttct tatgataaaa tcagtggaat ccatctgaaa gaagaaacca aacaagcaat
    59821 ccgtgaactc atcgaccagc tgtatgatga atatgtcggt atccatttga aaagcaaaaa
    59881 gttcattgat caaatgaagt cttgggcaca cgtattaaag acgtcagaga aagacatgtc
    59941 tgaaaaagat ctacctaaaa aagaagaata gtaaatgaaa catacaacaa aaaatcaaaa
    60001 ccatttgaca aacacaggga gttccgtcta ttattaaccg tagatcaaat agatcgttca
    60061 ctgagaggat ctattataga aacaagaaaa ctgcaaaatg aatacgtaca ttgaccaaga
    60121 tcagtaaaaa acacgtggtt tagcgagttc gggagagtgg gagccggacc caaacgattt
    60181 ttgaagaggc acttgcgagt acgataaatg aagctgccga atctttattc ggaagtaggg
    60241 tggaaccgcg aattattcgt ccctatgtct gtaatcagac atagggattt tttgtcgttt
    60301 tctttcctgt attcttattt gacagcaacg ctttaaaatt gaaaggggca aaacagatga
    60361 gtaaaaaatt gaccgtccaa gatatgattt taacattaca aaaattttgg tcatcaaacg
    60421 gctgcatgct gatgcaagcg tatgacacag aaaaaggagc aggtacgatg agcccatata
    60481 cctttttacg ggcaatcgga ccagaaccat ggaatgctgc ttacgtagag ccatctcgcc
    60541 gaccagctga tggacgttat ggcgaaaacc caaaccgttt gtatcagcat catcaattcc
    60601 aagtcgtgat gaaaccttca cctgagaata tccaagagct ttatttagaa agcttgcgcc
    60661 ttttaggaat cgatccacta gaacacgaca tccgttttgt tgaagacaac tgggagaacc
    60721 catccatggg ctgtgccggt gtgggttggg aagtatggct tgacggaatg gaaatcacac
    60781 aattcacgta cttccaacaa gttggtggac tgccttgtaa accagtaact tctgagatca
    60841 cttatggatt agaacgtctt gcttcttata tccaagaagt tgaaagtgtc tatgatttag
    60901 aatgggctga tggcgtgaaa tatggcgaga tcttcaaaca accagaatat gaacattcta
    60961 aatattcttt tgaagtaagc gaccaagact tgctactaag caactttgat cgttttgaaa
    61021 aagaagctaa acgctgtatc gatgaaaatc ttgttcatcc ggcgtatgat tatatcttga
    61081 aatgtagcca tacattcaac ttattagacg cccgcggtgc agtatccgta acagagcgtg
    61141 ccggttatct ttctcgcatc cgcaacatgg ctcgtgctgt agccaaaatc tttgtggcag
    61201 aacgcgaaaa attaggattc cctttgttga ataaaaacac agcaaatcca gaaaacgtga
    61261 aggaggctga ataagatggc aaaagactta ttacttgaaa tcgggctgga agaaatgcct
    61321 gctcatgttg tcacaccaag catgaaacaa ttagaagaaa aaacagcaaa atttttagat
    61381 gaaaaccaat tgacttatga tacgatcgaa acattttcca caccgcgccg tttagcaatc
    61441 aaagtaacaa acattccaga acgacaagcg gacagtgaag aagaagtcaa aggaccagcc
    61501 aaaaaaattg ctttggacgc agatggaaac tggacgaaag cagcggaagg atttgtccgc
    61561 ggacaaggtc tgacgacaga cgctatcact tttagagaat taaaaggtgt ggaatatgtc
    61621 tatgtaacga aatacactca tggtaaggaa tccaaagaag tattgacagg tttagcagat
    61681 gtcattaaaa gcctgacttt ccctgtaacg atgcattggg cagaatacga ttttgaatat
    61741 atccgcccta ttcactggat cgtggcattg ttagatgacg aagtaatccc attcgaaatc
    61801 ttggatgtca aaacaggcag agcctctcga ggtcatcgtt tcttaggcga agatgtgaca
    61861 tttgcgcatg caaaagaata tgaagaaaaa ttgaatgaac aattcgtcat tgcgtctccg
    61921 caaaaaagac aagaaatgat cgttacacaa gccaatgaat tagccgaaaa aaatcattgg
    61981 gttattgatc tagacgaaga tttactagaa gaagtcaaca atttagtcga atatccaact
    62041 gtcttttctg gcgacttcga agaaaaatat ctttctgttc ctgaagaagt actagtcact
    62101 tctatgaaag aacatcaacg ttatttcgag gtacggaatg atcaaggtat gctgcttcct
    62161 cattttattt ctgctcgtaa tggtgatcgg gtaaaattgg aaaatgtggt tcgaggcaat
    62221 caaaaagtat tgacggctcg tttagaagat gcggaattct tttataatga agacaagaaa
    62281 gcttcaatcg accaatacgt tgaaaaacta aaaactgtta ctttccatga aaaaatcggt
    62341 agtatctatg agaaaatgca acgggtacaa gtcattgccc gtatcattgg cgaacaagta
    62401 ggactatctg aggaagaatt gatggatctg caacgagctg ctgaaatcta taaatttgat
    62461 ctagtaacca acatggtagg ggaatttcct gaactgcaag ggatcatggg cgaaaaatat
    62521 gctctgctga aaggcgagaa acctgctgta gcgacagcga ttcgtgagca ttacatgcct
    62581 atatccagtg aaggagagct acctcagtct acagtaggtt ctgttttagc gattgcagat
    62641 aaattagata gcatcttttc tttctttgct gttgggatga tcccaagcgg ttcaaacgat
    62701 ccttatgcct tacgtcgcca agcatacggt gtcgttcgga tcatcgaatc gaaaaaatgg
    62761 gcctttcctt tgtctgttct gcaagaaacg attagcgatg ttatcagtaa agatacggat
    62821 cgtttcggca ttggtttatc agaagggcaa caacaagtga tcgactttat caaaggccgt
    62881 ctgcgccaat tattgacaac gaagaatatt cgtcatgatg tcatcgatgc tgttttgaat
    62941 gcggaacaaa aagatctgac aaaagtattt gcagcagcac aattgttcaa acaacatctt
    63001 gcagatgaag acttcaaacc ttcaatggaa gctttgacac gtgtcgtgaa cttagcgaaa
    63061 aaagcgcagc ttgaaaaaca atcagaagta gatcctgagc tgttcgaaaa cgacgcagag
    63121 aaagaattac acaaagcagt agaagcaatg aaagcaagtt ttgctgacca aacgatccac
    63181 gaaaactacg accagcttgt cgctcttcgt ccactgatcg aaaattattt tgatcaaacg
    63241 atggtcatgg ctgatgaacc agcagtacgt aagaaccgac taacacaact tagtcaaata
    63301 gctgccatgg ctttgtcatt agcaagcttg gatcaaatca tcacaaaata gtcttttgtt
    63361 tgaaaaacag agagcatgca cgaaacgtgc tgtgtctctg tttttt
//
LOCUS       DACDAF010000007        59854 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.007, whole genome shotgun sequence.
ACCESSION   DACDAF010000007 DACDAF010000000
VERSION     DACDAF010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.007"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(291..1601)
                     /locus_tag="IVZ69_000385"
     CDS             complement(291..1601)
                     /locus_tag="IVZ69_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP8182504.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1613..3031)
                     /locus_tag="IVZ69_000386"
     CDS             complement(1613..3031)
                     /locus_tag="IVZ69_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8182505.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3271..4839)
                     /locus_tag="IVZ69_000387"
     CDS             complement(3271..4839)
                     /locus_tag="IVZ69_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HAP8182506.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4843..5253)
                     /locus_tag="IVZ69_000388"
     CDS             complement(4843..5253)
                     /locus_tag="IVZ69_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HAP8182507.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5250..6173)
                     /locus_tag="IVZ69_000389"
     CDS             complement(5250..6173)
                     /locus_tag="IVZ69_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HAP8182508.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6170..7048)
                     /locus_tag="IVZ69_000390"
     CDS             complement(6170..7048)
                     /locus_tag="IVZ69_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HAP8182509.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7035..8372)
                     /locus_tag="IVZ69_000391"
     CDS             complement(7035..8372)
                     /locus_tag="IVZ69_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HAP8182510.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8375..9478)
                     /locus_tag="IVZ69_000392"
     CDS             complement(8375..9478)
                     /locus_tag="IVZ69_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP8182511.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9552..11060)
                     /locus_tag="IVZ69_000393"
     CDS             complement(9552..11060)
                     /locus_tag="IVZ69_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP8182512.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11026..11718)
                     /locus_tag="IVZ69_000394"
     CDS             complement(11026..11718)
                     /locus_tag="IVZ69_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP8182513.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11740..12714)
                     /locus_tag="IVZ69_000395"
     CDS             complement(11740..12714)
                     /locus_tag="IVZ69_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8182514.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13014..13886
                     /locus_tag="IVZ69_000396"
     CDS             13014..13886
                     /locus_tag="IVZ69_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8182515.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14344..16542)
                     /locus_tag="IVZ69_000397"
     CDS             complement(14344..16542)
                     /locus_tag="IVZ69_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8182516.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16774..17766
                     /locus_tag="IVZ69_000398"
     CDS             16774..17766
                     /locus_tag="IVZ69_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8182517.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17826..19247
                     /locus_tag="IVZ69_000399"
     CDS             17826..19247
                     /locus_tag="IVZ69_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HAP8182518.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19240..20739
                     /locus_tag="IVZ69_000400"
     CDS             19240..20739
                     /locus_tag="IVZ69_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009224330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HAP8182519.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20778..22172
                     /gene="uxaC"
                     /locus_tag="IVZ69_000401"
     CDS             20778..22172
                     /gene="uxaC"
                     /locus_tag="IVZ69_000401"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HAP8182520.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22331..23014
                     /locus_tag="IVZ69_000402"
     CDS             22331..23014
                     /locus_tag="IVZ69_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HAP8182521.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23016..23852
                     /locus_tag="IVZ69_000403"
     CDS             23016..23852
                     /locus_tag="IVZ69_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP8182522.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23863..25617
                     /locus_tag="IVZ69_000404"
     CDS             23863..25617
                     /locus_tag="IVZ69_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182523.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25893..26234)
                     /locus_tag="IVZ69_000405"
     CDS             complement(25893..26234)
                     /locus_tag="IVZ69_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP8182524.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26302..28473)
                     /locus_tag="IVZ69_000406"
     CDS             complement(26302..28473)
                     /locus_tag="IVZ69_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP8182525.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28684..29541
                     /locus_tag="IVZ69_000407"
     CDS             28684..29541
                     /locus_tag="IVZ69_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP8182526.1"
                     /translation="MKITITLPMNHPETTIRDLLEKEWLVPRKVRHFLRIRKNVWINQ
                     QPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDEHLIIVDKPAGMKTH
                     PNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKNPFVLPILGRMLEQK
                     MIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSALTHVTVNKVLSEQT
                     QVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHALELHMIHPFTQEKIV
                     GKALPGLWE"
     gene            complement(29612..30469)
                     /locus_tag="IVZ69_000408"
     CDS             complement(29612..30469)
                     /locus_tag="IVZ69_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP8182527.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30454..33156)
                     /locus_tag="IVZ69_000409"
     CDS             complement(30454..33156)
                     /locus_tag="IVZ69_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP8182528.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33169..34458)
                     /locus_tag="IVZ69_000410"
     CDS             complement(33169..34458)
                     /locus_tag="IVZ69_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HAP8182529.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34608..35654
                     /locus_tag="IVZ69_000411"
     CDS             34608..35654
                     /locus_tag="IVZ69_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8182530.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35656..37809
                     /locus_tag="IVZ69_000412"
     CDS             35656..37809
                     /locus_tag="IVZ69_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HAP8182531.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38282..39733)
                     /locus_tag="IVZ69_000413"
     CDS             complement(38282..39733)
                     /locus_tag="IVZ69_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8182532.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39730..41454)
                     /locus_tag="IVZ69_000414"
     CDS             complement(39730..41454)
                     /locus_tag="IVZ69_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP8182533.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41447..42061)
                     /locus_tag="IVZ69_000415"
     CDS             complement(41447..42061)
                     /locus_tag="IVZ69_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HAP8182534.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42406..43863)
                     /locus_tag="IVZ69_000416"
     CDS             complement(42406..43863)
                     /locus_tag="IVZ69_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP8182535.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43904..44824)
                     /locus_tag="IVZ69_000417"
     CDS             complement(43904..44824)
                     /locus_tag="IVZ69_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8182536.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44836..45783)
                     /locus_tag="IVZ69_000418"
     CDS             complement(44836..45783)
                     /locus_tag="IVZ69_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8182537.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46262..46981)
                     /locus_tag="IVZ69_000419"
     CDS             complement(46262..46981)
                     /locus_tag="IVZ69_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP8182538.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47030..48676)
                     /locus_tag="IVZ69_000420"
     CDS             complement(47030..48676)
                     /locus_tag="IVZ69_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP8182539.1"
                     /translation="MDNQRKPSLDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48855..49445
                     /locus_tag="IVZ69_000421"
     CDS             48855..49445
                     /locus_tag="IVZ69_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP8182540.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49537..51042
                     /locus_tag="IVZ69_000422"
     CDS             49537..51042
                     /locus_tag="IVZ69_000422"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HAP8182541.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51126..52478)
                     /gene="celB"
                     /locus_tag="IVZ69_000423"
     CDS             complement(51126..52478)
                     /gene="celB"
                     /locus_tag="IVZ69_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP8182542.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52478..52996)
                     /locus_tag="IVZ69_000424"
     CDS             complement(52478..52996)
                     /locus_tag="IVZ69_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182543.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53012..53338)
                     /locus_tag="IVZ69_000425"
     CDS             complement(53012..53338)
                     /locus_tag="IVZ69_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HAP8182544.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53351..55330)
                     /locus_tag="IVZ69_000426"
     CDS             complement(53351..55330)
                     /locus_tag="IVZ69_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP8182545.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55351..55665)
                     /locus_tag="IVZ69_000427"
     CDS             complement(55351..55665)
                     /locus_tag="IVZ69_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HAP8182546.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55833..56126
                     /locus_tag="IVZ69_000428"
     CDS             55833..56126
                     /locus_tag="IVZ69_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HAP8182547.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56204..57316)
                     /locus_tag="IVZ69_000429"
     CDS             complement(56204..57316)
                     /locus_tag="IVZ69_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP8182548.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57517..57693
                     /locus_tag="IVZ69_000430"
     CDS             57517..57693
                     /locus_tag="IVZ69_000430"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182549.1"
                     /translation="MITEVSYETLQKKKTLIVAAVLFPAPCVCRNCGSAVVDGNRKLM
                     VVKNKKKETIVHFE"
     gene            57703..57882
                     /locus_tag="IVZ69_000431"
     CDS             57703..57882
                     /locus_tag="IVZ69_000431"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182550.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58076..58246
                     /locus_tag="IVZ69_000432"
     CDS             58076..58246
                     /locus_tag="IVZ69_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP8182551.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58670..>59854)
                     /locus_tag="IVZ69_000433"
     CDS             complement(58670..>59854)
                     /locus_tag="IVZ69_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen binding domain-containing protein"
                     /protein_id="HAP8182552.1"
                     /translation="TLQTGLTTGEDGKLAIDGLAPGAYQLVETQAPIGYELDATPIEF
                     EIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEILQGAVFELQNREGETLQTGLTTG
                     EDGKLAIDGLAPGAYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKANRLTPGGV
                     VLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGVYQLVETQAP
                     TGYELDATPIEFEIERSQTAVVELTKENRLTPGGVVLTKIDDQSGEVLQGAVFELQDA
                     NGTVLQSGLTTGADGKLAIDGLAPGAYQLVETQAPTGYELDATPVTFKIEKEQEVAIF
                     LTKENRKVADSSDIRGNNPTSSGNKHLPKTGETIISQFILSILGVLLVFISIKFRKKR
                     NI"
BASE COUNT        17855 a        12259 c        10474 g        19266 t
ORIGIN      
        1 aaaagttttt ttcgatttcg tttttcgaaa tctttcagca actcatttat cataacttat
       61 cgtttgttat ttgtcaagaa cttttttgaa gtttttttcg atagaatcaa gcttcgcaag
      121 tggttctttt taacgactta gttatcttat cacgtctaaa aacatgtgtc aactcttttt
      181 tggaattttc ataaaatgtt tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa
      241 aaaataaagg tcaagctaaa atattattta agcttgacct tattataatt tcaacgattg
      301 tcaaaagtat tgtttgcagc tgtgttgcca gtttctatag ataaatcaca gcttttgaaa
      361 cataagtttt gtactgcttc gattcgcccg aattcttttg cagttatttg gcaatgagaa
      421 aagcagacat cttctatagg cttttcagga aatgctacta aatcaaaagc tcgggaagga
      481 agtgagtaac ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc tttgactttc
      541 gtcatttgct ttgattcagg tatttcttca gccactgctt gccaactttc tggcatttga
      601 gcaaggtcat tgctattttt tctattgtat tcattatgcc agtccattat ccaagaaaaa
      661 ggaaattgta catcaatcat attcagattt tctaccctga tattttcgat cactccccct
      721 ctttcttttg aagatttcat tcgaatacca cagtctgact gaaaaaaatc gatatcgtga
      781 atatatacgt cactaactcc agcactaact tcgctaccaa tagttacacc gtatcctgaa
      841 cggattttac atctagcaac ctcgattctt gatgattttc gattgactct tgcaccattg
      901 ccatctctgc cagacttaat agcaatacaa tcatcaccac aggccaaatc acattcatag
      961 acacgcacat ttgttgaaga atcaatatca atcccatctg tacttggtcc atcattgttg
     1021 cggatgatta ctttttctac taatacatcg ttagaataag tgatttgcaa gttccaaaaa
     1081 cctgatttct gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata cagtaaacaa
     1141 gcgcgtggac gtttaatagc ataatccgca atccaacgaa gtcccttttg atcgtattca
     1201 gctcttgtcc cgcttttttg atcttttccc caatacagct cccaccaatg gtctccttga
     1261 ccgtcgatta ttccttttcc ttctataaga atatctttcg ccgagagaac attcaaaatc
     1321 gctgctggcc atttcatttc tacgccggct actcgtgtat cgatttctgg aaatgcttcg
     1381 atatctgttc tccccttgag gactgcacct tcttcaaaga taagatgact cttatctttt
     1441 aaaaaaaggg ctccgactaa ataaatgcct tttggaataa atacaggtaa gtgttctttc
     1501 gcaccttgat cgattgcttt ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt
     1561 ttaaagttca aagcattgat aatccctttt tttgtccgca atacgtttct ccctatcttt
     1621 cattgatttt tttcaattct tcaccaataa atacagtttt tgaacgattc agtgggtaac
     1681 ctactagcaa aatgattgcg gatacaaata agcagaatgc tggtaacaag tttgccatcg
     1741 tataaatcct ttcttgtact aaaactgatt ggatggctcc acctgttgta gacgattggt
     1801 aaccaatgag tgccagcata aatccgccta ccgctcctgc acatgcttgt cctacttttc
     1861 tcgcaaaaga atttactcca tatactgttc catcttctct taagcctgtc ttatattgat
     1921 gataatcaat cacgtcagta atgaatgccc agaccatcaa attgaataaa ccagatccta
     1981 aagtagcgat aaataaaaga atcagatata cccatgcatt tgttatatga aggaaataca
     2041 tcagcaagta catacatgaa gaagcaagta acgcaaatac gcttgcttcc tttttaccaa
     2101 ataattttgt cagctttgta gcaaatggtg ctaaaactac tactgttccg taagtaaata
     2161 aaagagcaac agacattgct tgtttattat ggaagtaatc attgaataaa taagtcatat
     2221 tcgtcccagc taaaatctga ttgatcacaa tgaaaatgtc aacaatgact aaaataatca
     2281 gtgctcgatt agctaacaaa ccttttacca actgagaagc agatactttt tcgtttttga
     2341 caactcttac tctttcagta gtcaatttac aagttaacat atatgcgaca aatgctattg
     2401 cagcacatcc gattgaaatc caaaagaaat gattccctga aacgacttgt tgtccactct
     2461 tgttatgggt atacattaaa atcggaatga agaatcctgt agttgatccg ccaatcgcag
     2521 aaccaatgct tcggaacgtg gacaacgagg tgcggtcatt aggatttgag ctaattgctg
     2581 ctgccattgc tccatacggg atattgattg ttgagagaaa aatcccataa acaatgtatg
     2641 aaacaaaaat ataagcaatc ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca
     2701 aaatgacagt cactaagcaa aatggatact tcatttttct gatccaagga ataaatcggc
     2761 cagtttctgt taactctgag acatcacata atcttccaac catcacatca gcaaacgcat
     2821 ccaaaattct cgaaatcaag aataacgtac ctacgattgc ccctgaaacg ccaagaacat
     2881 tcgtataata aatcatcaag aaactattga ctaaacctaa aataaaacag ttacctagat
     2941 caccgaacat gtagcctatc ttatcggaaa tcccaaattc ctttttttct ttttttattg
     3001 tatttgctgt aacagcattt tgtgaaagca tttgaattcc tcctacctct tctagtaaac
     3061 gttttcaaaa ttataactct ttttttcttg tttttatatt cacaatgttg gctttttatt
     3121 gcattatctt gacagataaa aaacaaaaaa taatctaaaa acattgatgc ataagattga
     3181 taactttttt tacataacaa tatatacaaa caaaaaaatt cactaactag tgaaaataag
     3241 ttagtgaacc tcatttatta aagaattaaa ttacagatga tcttttccat catacttgaa
     3301 aaactcaaaa tcagcataac ttcctctttt tttatttaga tcatgcactg ctatcccgat
     3361 aaaatttcca gtaaaccctc ctgagagtat acacatgttt ttttgcggac ctactttctt
     3421 ccattcttca gttgatacgt ctttcaaatg aaactgtgct gtctctttct ttacagtgac
     3481 tttcaaaaaa gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc
     3541 gttttctgat tctatcatac gtaggcattt tcccttgtcc tcattccaag taacataaca
     3601 ataaatataa ttggattcat ttaagtacag taccagtcca gccatctgat taaaattatt
     3661 aggcatgtat tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa
     3721 caaatgatgt tcgaaggtag attgaagaga ttcaccggaa atcagacgta aaaaacctgg
     3781 tctacatttt gtatcacacc aatcagcatt tggcaaaatg cgtctggcat tccagttctt
     3841 ctttagctct ccttcaaatg tatccataaa ctgatgatct ttttcttgtt gtacctcttc
     3901 atttgtctca atcattattt cttccatcgg agttgtctgg ctatctttaa gtcttaacca
     3961 atcgtcggac gtccaataca cttcttgaat agcggtttct cttcccaaaa tagccgcacc
     4021 gtttaatggt ctggtacaaa gatatgtcat gtaccatctt cctgacgggg tttgtactaa
     4081 gctcccatgt cctgtacatt gcaatgtaga agcaggtttg tcactagctg tcagcatagg
     4141 aaaaccagga tcaagctcgt aaggaccagt aatattcttt gctcggcaaa ctgtaactga
     4201 atgtcctctt cctgtaccgc cttctgccgt catcaaataa taatacccgt tacgaaaata
     4261 caaatgtggt gcctccgttt tcgctaattc tgtacctgca aatattttat agatgggacc
     4321 atcaagcttc ttcttctctg catcatattc ttgtaatacg ataccgctgg atttattcgg
     4381 tgtgtccaga cgataatccc atagttcatt gacaagccat ttttttcccg tttcaagatc
     4441 atggaacaaa gaaggatcaa agccgttact atttaaataa attggttcgg accaaggacc
     4501 tgtgatctca gatgcagtga tcaaataatt gtggacatct ttaaacggac ggcctgcact
     4561 tttgacatct gtgtaaacaa gataaaacaa tccatcagca taactgatct gtggcgccca
     4621 tatacttcca tttgtaggat ttccttgcaa agatacttga gtggtcaaaa tatccgttgt
     4681 atgtgaccag ttgactaaat ttttcgactc atatactcgg attcctggaa gccattcaaa
     4741 agaggagaca ataatgtaat accgctcttt cactcttaat atattaggat ctggattgaa
     4801 tcctcttaaa ataggatttt tcactttgat agtctgcatg attcaggctc cttttctcat
     4861 tcttactcga tataaactga atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc
     4921 aataaactga gtgccaatca acaatatgaa tcctgttata aaatacaaac cagtggcagt
     4981 tgttaagtat tttcctttag cagtcaaaaa caatgctact gctaaaaaag caagtgaaat
     5041 aaacaacaca acggcaaaca gaccagtcat gtcctgtaat aatccaaatg tattttctaa
     5101 agacaaagtt gaatgatcta cagcaagcga ctgataactt tttttaaact ctgacgcaga
     5161 catattactt aaagtaactg ctaacccgcc aaagaaaatc aaagatagac tgccaccgac
     5221 cattcctagc aatagttccc attttctttt catttctgaa ccccctgctt ttctaaatgt
     5281 atccattcag gtcttttgat cgatgtttca taattgttat tacgttcaga gaatttgaca
     5341 gtctgttcat ttttcttgtc atcccaatta tcccaaccag ttgggtgaac atgcccacct
     5401 atcttacacg cttcaaataa gacatttgca tacggacgcc acggtcttcc taaatagacg
     5461 tttctagtat caggttctgc agtcaaggta cagctttcaa aacgataccc tgttttttga
     5521 tttttcggcg tagatgctgc tgtgatgtat ccaggatttt tactggctaa gctatggata
     5581 tgacactgat gaaaaacggc atctgcccca ccaaatatga aatccaccgt tccttcaatc
     5641 cagcaatatt cataggtctg acgacaatac tcaggattgg cagaagccgg tgtacaaaaa
     5701 ggagtaccat ctttttgcaa atcaggcaac ggacccgtgc ataaggtatc ctgataacca
     5761 gatagtcgac agttttttaa agatacgcga tctcctgaat tgaataaagc aacagcctgt
     5821 cctacctttt ctcctggacc tgctgtattt tcgatgtgaa gattttctaa tacgacattc
     5881 gatccttcta agaaaaaagt agcacttcgg aaagtcccta actggctacc gtcaagatac
     5941 tcctgttttg caaaacgatt accggagata actactgttc ctgctcccac aagtttaaaa
     6001 ttggataatc tgctttctat atattcatca tatcttcctt cttttactat caagaccttt
     6061 ggatggctat ccggcaggcc tgccaaataa tcgattcctt cttggatagt ttcaaaatcc
     6121 gtcggggtat ctatagcatt ctttccaatt atcagtttgt ctttcatcct cataaatgct
     6181 cccttatgaa ttgtttccaa atatttctca tttcttgtgt ttccatatga ccgcctgtta
     6241 aagaaaaaga agaaaagttt tctggactac ccattgattg atactttttg tccagccctt
     6301 ttctcagctt cagtacgcct tcgtccaagc acatcgtatc gttttttcca actaagctaa
     6361 gacgagggcg cggagcgatt ttttcttgga ttgctaacgt tgtataagct gtcaatagat
     6421 ttggcacata gtaataaaac ccatgatgat ctaggcggcg atgtagcaaa agtatttcga
     6481 tgtccacctg tgccgctaga tcaatacaaa ctttgacacg agaatccaat gctgtcaccc
     6541 accagcttaa taagcctccc atagaaagac caatcgttgc gagccgttga gtatctgtgt
     6601 cttcccttgt ctccaaataa tcgatcaagc tgatcacatc ataaatacgc attccccata
     6661 acgtttttcc tgttaataaa aattgtttga acaactcgct ttcagaaata cctccgcgtt
     6721 cttcaaatcc ccaagcatca atcgaccaaa cagcatatcc cattcctgtc agtacttctg
     6781 caaaagatgg agaagctaag taaggagcac catggatcaa ttcacttttc ccgactgaaa
     6841 aatctccgcc gtgagaatgc aggtaaagga ccggcggaaa cggtccttct ttttctggat
     6901 aagcatagag ggctggtact gtttccaatt catttaagta caattgatag tattcaagca
     6961 taaaaccgtt ttgtttttct cggtataatc gttttccact aggggtatgt ctgctagatg
     7021 gagcacctaa aaaatcattc aactgcataa gcaaagtttt tacgaacaac cagttcatcc
     7081 atattttctg attgatttga ttggaatttc tcaatactga tttctttagt attttctaat
     7141 agaaatgctg gtccctcgtg attttcaatc gacatctggt taaaggaaac cttacccgca
     7201 aagccaatat aaaatccttg tctgctcatt tcctctattc ctgtcatcat agcaggaaca
     7261 ccgggaactg catcttgggc catcgagaca tcgatattgt caaatgtgat ttcttgtatg
     7321 aattgttccg ctaatccata aataaaacct gcagaagcat ggacattcct tgccgtgata
     7381 ttcgaaaaat ggatccttct gaatgctggt gtccgttcat ctatcggata agcctttttt
     7441 tcccatacat acggttcttt ccctcgcgga ccacagaaat aataaagatt cagtataaat
     7501 ggacacatca cattatccat gactatattg gatactcgaa tatcttcaac gatcccgcct
     7561 cgacctcgtc tagatttcaa tcgtattcct cgatcagttt cttggaagat acaatttgaa
     7621 atggtaatat tacgaatact accactcatt tcacttccta atacgacacc gccatgtcca
     7681 tggaccatcg tgcaatttgt gatcgtgata ttttcgcaag cgatcctttc gtacgtatct
     7741 tcagtccctg ccttgattgc aatacagtca tctcccacgt caatatggca attactaata
     7801 cgcacatttt tgcatgattc tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc
     7861 aagatcgtca agttatcaaa cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt
     7921 ggtgactgga tcaatttaat atctttcaca gtaattcgat gacagttatg gaaactcatc
     7981 aatttaggac gaggataagc gagattatct ggttcatttc taaaagtatg ccaccatttt
     8041 tttccatttc catctaatgt accgaaacca gtgacagaga tgttctctac attttgagca
     8101 tagatacagg aagcataaac ttttcgatgg actccttccc aacgtgaatg aacaacagga
     8161 taatcttttg gatcgtcaga gaatttcaga accgctcctg cgcttaaatg aagttcgaca
     8221 ttgcttttta aaaataaagc tcctgttaga aattcacctg ctggaacaac tacggtcccg
     8281 cctccgtcac ttgctgcagc atcaatggct tgttgtattg cttcagtatt caattcatca
     8341 attgatgcgc caaatgtcaa aatatcatac atatttataa tgcctccact tcaatcaatg
     8401 cttgcaagaa tgcaccaacg cctttttgat cattacaaat aattggttca ctgatgtagt
     8461 aagcatatga accatctcgc tgatctgctc cgcctaaccc tgctacttga cagtttttat
     8521 tcaagttcag ccagccttct tttgtttcca gaacaaattc atcaagtaat ccttgatgtg
     8581 atttcttcac ttgtggaagc cattcttctt tgttcagcag tcccaaacgt attcctttag
     8641 ccattgcgta aacaaacata ctactgccgg aagcttccag ataatttcct ttccgttttg
     8701 tttctgttgt tacttgatac catgtcccgc tgttttcttc ttgatatgga agtaatgcag
     8761 ccagtgtctt ttctagaatt tctttcagca aagaacaatc tgtttcttca tgaagtaatt
     8821 cataggtatc tgctgcagcc atcaaatacc agccaatcga tcggctccaa aaatgatggg
     8881 atagacctgt ttttggatca gcccatggtt ggaccttctt ttcatcccat gcatgaatca
     8941 gcaaatttgt ttttggatcg aatagatgtt tataactgat ttcaaactgt ctcaaaacat
     9001 cttggtaatc tttttcttca ctaaaattct ggataaattc agcataaaaa ggagaaccca
     9061 tatataagcc atccaaccaa atttgataag gataaatttc tttatgccaa aaagctcctt
     9121 cggatgtgcg tggatggttt gccaactgct gggaaaggag ttctgctgct tttttatatt
     9181 tttcttcgcc tgtttctttg tacaataaaa agaaaagctt tcctgtattt acatggtcga
     9241 tattgtattc ttcaacgctg tagccacgga tcgttccatc ttcttgcacg aaatagtcga
     9301 tattgtcttt tatgaaatca aaataaattt tttcttgggt tcgttcccaa agtaattgga
     9361 accctttaag tacgacgcca tagtcataag accattttcc tttataccac ttttcttcat
     9421 ataagcgagg tgttctttcc atgatacttt ttgctaattt ctttgaccag ttttccatta
     9481 tttgctctcc tttaaaaatt aaaataggat ttgggacaaa taccaagaag tatttgtccc
     9541 aatcgtctat attactgtgc cgctgctttg tatgcttcct cgtactcttg tgtgattcga
     9601 tcgcctcctt gtgctttcca gtcttctaca gcttttttga atccatcttc gtcaagctgt
     9661 cccatgatgt attgcaccgt agcatcaatg acgatttttt caatttctga tcctacttca
     9721 ttgttcgtcg gtgaatccaa tggcacagaa ggatccatta cagcaaattc ttcattttct
     9781 ttgatcaatt gattagagaa ttctttttca gggtctgtat ctttgaaaga gaacgtcact
     9841 tcactaggac gagagcttga taacggttgc acctcttgtt gccaaagatc catatcgata
     9901 aattcgatag aaccatcatc attcaattca taatgcgttc cttcgatacc gccagtcatc
     9961 aatttataca catcttcttc taaaagatca tcaacaaatt gaagtaattt cttcaattgt
    10021 gcttcgtctt ttacttgaga tttgggaaat gctagcaagc cgccaatacc atttccttct
    10081 gaccaaacat gataaccgcc gccttcacca tctgagatct tgtttacagg cactaattcc
    10141 atatcatctt gaataccttg acccatcgtc ttcagattct tgatatccac cattccagtg
    10201 tagattccag ttcttccttg tgcaaattgt tcttgctgat cagtcttttg ggtaactgca
    10261 aagtcttgtg ccaaatagcc attctcaaat agatctcttg aaaaattcaa agctttcata
    10321 tactcttctg tatcaaattc tggagtgaat ttgccattat cgtctacagc ccagccattt
    10381 ggtgctccaa aataagaagt gaaaagttta aagctggtat aacgaatatc actaggcgca
    10441 cgatcgccaa aaccaactgt gtcgtccaca ccatttccat caggatcgtt ttctgtaaat
    10501 tgtttagcta cttcataaag ctcatccatg gtagttggaa catctagtcc tagattatcc
    10561 aaccagtctt ttcgaatgac taagccagca cgagcgtagt ctttttgtat cggtacgccg
    10621 tacaaggcac cgtcgatact cgcagcttcg attctatctt cagaaatttg acttaaattt
    10681 ttatagtctt ttaaatattc tgatacatcc cagaatacgc ctgattttaa cgcattgcgg
    10741 acagaagagt ttttcaacat cgcaatttga agtgtaacga tatctcctag ttcatcagaa
    10801 gccaatgcag ttgttaatct ttcttctttt gaagcatcag gaatccagtt gaatgtcagt
    10861 tccgtatcgg ttttttcttc gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga
    10921 tgcaaaatat ttaaccaagt gattttagct tttccatctt ctgtctctga agaactgtta
    10981 cttgaactgc tgccgcatgc ggcaagtgct agaattcctg caaaactaag acctaatttt
    11041 acgagcgttg cttttttcat aaattttctc cttcactgtt ttaataatat ttttgttttc
    11101 ttctgttttt tctgtatatg agttcttcca ttccaaatgg caaaatatag aatttgctgt
    11161 ccacgtgact gcggaaaaga agagactgcc accgataaag gttaaaacac ctggcattgt
    11221 ttggatgatc atcagataaa tccctaccat acttaatatc aacactaatg agtaatgaag
    11281 atgtgagaat ccgaataaaa atgccatttt cattttgaaa aaatatcctt tccaatcata
    11341 atgagccatg attgggaaaa tatagagtgc tgagagcaca tatatgaacg cagcaatata
    11401 caaagcgatc ctaagatacc aattgtgtat gaaagaaaga tccacaagta aaacaatccc
    11461 gatggcgcca tatatccagc tcatcagcaa ggtttcacga tagttttctt taaaatatgt
    11521 gaagtacgtt ttcgtcaaag gaaacgtttc ttttgagcgc agccattttc taatcactgc
    11581 aaccatcgca tacgatgcag gaccgaaagt aaaaactccc aaacctgcga tgactaaacc
    11641 gccccacaga aaattcaaat aaaccaactg taaaatacga tttagccttc cgtttatttt
    11701 atctaatgac tgcagcatat ctttccctct ctttctatct tagtaaacgc cgtcttctcc
    11761 tagctttttg gcaatcttat tagctaaaat taccataaac aatcctacga cccctttaaa
    11821 caatcccatt gctgtactga aacttaactg tccattcttc aatccagctg tataaatata
    11881 ggtgtcgaaa atttctgcaa cgcttcgatt caatgaattc aataacaagt acatatgctc
    11941 gaaccctaag tctaatgtct gaccgatttt tagaatcagc aaggtaatga ttactggacg
    12001 aattgccggc aatgtaacat gccatgtttt gcgtaagcgt cctgctccat ccatttctgc
    12061 agcttcatac aactgtgtat cgactgcagt tatcgctgaa aggtagatga tcgtagacca
    12121 gcccaactct ttccagatca cttgtccgat atatactgtg cgtgtccatt caggggatgt
    12181 tagaaaactg attttttcaa atcccattgt tgcaaggaat tcattcaata cccctccgtc
    12241 aacattcaaa aatacataag taatcgaaac aatgattacc caagacatga agtgagggat
    12301 gtaaatgatc gtttgaatcc cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa
    12361 agacaaaatg attggcatcg gaaaaaacac gaagatattt aatccgaaca agatcaacgt
    12421 atttcttaat aatgtaaaga atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc
    12481 gacccaagga cttcccatta ttcctaaaaa tggttgataa tcttgaaaag caataacgag
    12541 tccccccata ggaagatacc taaaaatcaa gaaataaagg actcccggca gaatcatcac
    12601 atataaaaat ttattcgttt tgattcctgc aattattttt tttcgtcttc tgagcttttc
    12661 ttcttttttc gatagcgtca gttgaaatgg ttcttgtttc tttacacttt ccataagccc
    12721 ctccttagtt ttgtgaatgt ttgctgctta tgacttcatg atagataact atctgaatta
    12781 cgtatataat catttttacc gtaagtaaaa acgcttacat agcaatgatt tttgtgctat
    12841 acaaaacgat aaagtgtatt ttttcacaaa taaactacgc atagcaaacc ttctattttt
    12901 ttctatctga cacttagcat aggaaatgat tatatacgta atctttcacc gatgataaat
    12961 tgaacatata gaaacagaaa catttaattt attttgagga ggagcctatc tatatgaaaa
    13021 agaaagtctc tataggagaa agaagtttta cacttttcaa caatacgttt ctaattttgc
    13081 tagctttgat ctgtatcgtt ccttttttaa atatcatcgc tacatctttt gcttctacac
    13141 aagaagtcgt cgcgaaaaag tttatccttt ttcctactac cttttcttta gacgcgtatc
    13201 gctacattct ttctacgccg accattttta gagcacttgc tgtttcgatt ggtgttacag
    13261 gtgtcggaac gatcgtcagt atgtgtgcaa cttcactgat ggcctacggt ctttccagaa
    13321 agtatttgtt tggtcgaggt ttcgtcaact ttcttgttgt attttctatg ttgttcagcg
    13381 gggggatgat tccaacgttc ttagttgttc gttctctagg gctggtcaat tcttactggg
    13441 ccatgatcct gcctgtggct gttaatgcaa tgaatatgat cattatgaga aactttttcc
    13501 aagccttgcc ggatagtttg gaagaatcag caaaaatgga tggttgcaca gattttggtg
    13561 tatttttcaa aattatgctg ccattagcgt taccgtctat tgctactatc tcgctttttt
    13621 atgctgttac ttactggaac acttatatga ctgctatttt gtatatcaac gattcatcta
    13681 aatggccgat acagattctt ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag
    13741 aaagtagtgc cgttgatgtg attccaccag cacaaacagt taaaatggct gttatcgtta
    13801 ttgcaacagt gcctatgctg attgtttatc cttttgttca gaaatatttt gtcaaaggag
    13861 cactcgtagg ttctgtcaaa gggtgattat gtactgaacg caaaatggta gttgtgtcag
    13921 aagtggtcag cttcaagaaa taagaaggca tttacgaaaa ttgcttctta aatttttgtg
    13981 aaatttcggc ttatttttcg aagaatctac tcctggaaca ccgtgtatca gaggttgtga
    14041 aagagacgtt cagccttgag cgatgataaa aactctcaca aacattgcga cgagtaaccc
    14101 acaggagcaa taagaagcga ttttgaaaaa tagcttccca tatttcacaa aattatgcct
    14161 tattgtcgat agcctgtctc ttgaacgcca tttattcgta aaaaagaact gtgacaagac
    14221 ttttgtcaca gttctttttg cgtgcttagc cttgaaattt aactatccat aaatacaaat
    14281 actagggtta ttctaacttc ttttattgct tgaatcagtc cacaagaaaa acagcctctt
    14341 gattcacaaa tatttttttc gatattctcc cggcgtaatc gattccttct ttttaaagaa
    14401 acgaataaaa ttttgcggat ttcgatattg caatctttct gcaatctctt ttacggagag
    14461 gttagtctct ttcaaccatt tttttgctac ctctaaacga tgattttgaa caaaatcacc
    14521 aaatttttct cctgtttcct ttttaaatac attacttaaa tagttagggt tataatgcaa
    14581 cctatcagcg atcacatcta aagacagatc acgatcatat tctgtgtaga cgatatgcat
    14641 aatattctcc gacaaatttt taaattcatg atcagtgatt gcttgagagc attctgtgat
    14701 tggcagaact aattgttcta aaacaagttt ttctagttct ttgggatgat aattgttcag
    14761 tgcttttaca taaatttgtt tcatgttatc aaagtttttt gaatctactc ccaataactg
    14821 tcctaattga acgagttcat tgatcaagcg gaccgaaact acttcccgac tcaaaggatt
    14881 tttattttgt gcaaacaatg catcaatcaa ttcatgtact aaattcttca cttcctgatt
    14941 tccagaacga atggcttcaa acaatcgatt ttgttcttct atcggatatc taataagtgt
    15001 tttttcatga gcagcaggaa cgatttcctg ataaaaaata attgaacttg gaccagtatt
    15061 tacacgataa tacagggctt cttttgcccg atcaaccgat tgcttgcttt cattcagcgt
    15121 ttcgaaccgg ttactgatgc ctatactgat agttaaattc aagtattctt ttacacgttt
    15181 ttgaatgagt cggcaatact ccatgacttt tttgcttgct tctgcatcat ctttatccat
    15241 tcgataaata gtggcttgca tttcttcatt caaaacgatc ggcagcattc gattttcctt
    15301 tggcacaatt tccgtgatca tgttgttgat cgctaaaagt agcaaatcac gctccccacc
    15361 gtgactatct tctaacagat cgatttgaac caaagctgta taatagcagt cattttgaga
    15421 actataacca aattgctgca accgctgatc tagttctcgc ctttctactc gatttctaaa
    15481 taaactaagt acaaatagcg tttccagctg tggcttttgg gtaactaagt gtgcacttaa
    15541 cgcttctttt tctcctatga tccgactgac tgattgagcg accaaatcta gttctttccc
    15601 actgaatcct tttgatttaa gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa
    15661 tctgtccgaa aataagtagg aaagaagacc aatgagtcct accagtgtta aagacactgc
    15721 aactagcccg attctcagat tgcggatcat tgcgccaatt gcactagagt caacttctaa
    15781 tctgtaaatc caattattat aatctgattt cagtactata tacgttttat ctttttctct
    15841 tatcactttc agctgattgt aatctagatc cacgtccgtt aatacagttg gttgctcttt
    15901 attttttact gtctgagtag taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc
    15961 ttctccactt tcaccaacaa cttgttctat tgtatgtttc tctatcgtag caattcccaa
    16021 tgcatatttt tctttttcaa acattggcaa agaaatcacc atttcgattc ctttgttttt
    16081 cttttgccaa aataaattat ttttgttatt tatgtacttc tgttgatact tttcaatttc
    16141 ctcttcggtc agttgactca acgatccatt gattactccc catttaccag ccaaactgac
    16201 taaatcataa ttattatcat ccataacaat cgtttctata aaatttagtt ctttcctgat
    16261 ttcagaataa gtggagtaat ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt
    16321 tttggtcgaa ccatacgtag aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt
    16381 agttttaact tgcctgagca aattcttttt gtctgttaaa taactcgatt cgatcgattc
    16441 ataggtattc tggtaaatga ataaactaaa tcctatgaca agtacggctc ctaataaaaa
    16501 catcggtaaa aatattttat aaaatactgt acttttcttc attttcttcc tctcctcctt
    16561 ttaaaataaa aggctttcat ttttctgtaa aattgatact catctaatta aatgagcatt
    16621 ccccgctttc aagaatagca taattaaaaa taaaaatcca agtaattttt aacgtgtgca
    16681 atcttttcat atcaaagatc tattgactta tcgtagttat cgtaatatga tgaatgcgtt
    16741 aacaaaaagt gaaaaagtaa ggaaaatgat ggaatggtaa cgatcaaaga tgtcgctaaa
    16801 gcagctggcg tttctcatac gacagtttct cgtgctttga ataacagcag tttaataaaa
    16861 aatgaaacaa aacaaaaaat acgacaacta gctaaggaaa tgaattattc gccaaactat
    16921 agtgcaaaag gtttagtgaa tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg
    16981 cataaaggaa cttcatcaaa tttcctagca gattccattg caggcatcca ttcagtatta
    17041 gacacaaatt acagtttatc tgttgaaagt atcgatgttg ttgatttaac agaaatcaac
    17101 ctgcaacgct acgatggact gatcgttatg agtcaaagtg atgatgatca gcctttcatc
    17161 gactatctca aagaaaaaga atttcctttc gttgttgtca atcgtcacat caatgatcca
    17221 gcggttatca acgtcactgc cgatgatgcg gccggtgtta tgcaggcagt agattacggt
    17281 attggatgcg gacatacgaa gatcgcttat attggcggaa agaaaaattt tcgttcgaca
    17341 aaagaacggg aaaaaggggt attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca
    17401 gcctattttt taacaggaga ttacagctta gaaagcggcc tccaaaacat ggaataccta
    17461 ttatcacttt ctgacctgcc tactctggtt ttttgcggca acgacgacat agcgattggt
    17521 gcattgagag ctgtacattt agctggcctc cgtgttcccc agaacatttc tctgatcggg
    17581 ttcgatgatt ctccagtcgt ctcctatctc aatccgccgc ttaccaccgt acgtaagcct
    17641 ttgaaagaaa tgtgtcaaga aggaacaaag cttttactag atttgatcga aggcaggacg
    17701 atcgaacaat ctaaaattga gctctccacc ttgttgatcc ttcgtgagtc gatcaattac
    17761 ttgtaaacta caagtaattt tatataaaaa tgttaacgtg tgcataacac agaaaggaag
    17821 tttatatgaa aaaactgaca aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc
    17881 ttcagtttgg tgaaggcaat tttatgcgtg gatttattga ttggcagatt cagcagctga
    17941 ataaccaaca attgtttaaa ggtaatgttg caatcattca acctttagaa caaggtcttg
    18001 gaaatatgat gaaccagcaa gataatttat atacggtcat tttacaagga ctcagcaatg
    18061 gcgaaatcgt tgatacttcc gagattatca ccgtagtaga acaaatgatc aatccttatg
    18121 atgaatggga tgcttatcta tctctagcag aaaatgacga cttggcctat atcgtctcca
    18181 atacaacaga ggcaggaatc caattcgtgg agactgataa tttaacagat actcccccac
    18241 agagcctccc gggcaaactg acagcctttt tataccgacg tttcaaatta aacaaagctg
    18301 gctttaccat cattccttgc gaactgattg acagaaacgg cgaacgtcta aaagaaatca
    18361 ttttacgcta cgcagaaaaa tgggatttag aacctgcttt tgttgagtgg ttagaaaaag
    18421 aaaatgtttt ctgttgtagt ttagttgatc gcatcgtccc aggttatcct cgcgaagatg
    18481 caggtgtttt caatcaacgg cataactatg aagatcaatt gatggtcaaa gcagaaccat
    18541 tcatgctttg ggtgatcgaa gggcctaaag aattggagaa tcaactacca ttcaaacagg
    18601 ctggcttgaa tgtcatcatc acagatgata tgactcctta tcgtgaacgt aaggtgcatt
    18661 tgcttaatgg accgcataca gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg
    18721 tagaagaagt aatgaaagat cctttattct ccgcatatgt tgatcagtta ttcaatctag
    18781 aattgattcc tatgctttct ttacctaaag atgaattagc catttatgct gaccaaatca
    18841 aagaacgttt cttgaatcct tttgcccatc acaaattaga agcgatttca ttaaatagtg
    18901 tttcaaagtt cagcacccgt ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc
    18961 aggtaccacc gttaatcact gtttcactag ctgcgctact tcttatgtat cgaggcgatc
    19021 aagtaaagcc acatgatgat gaaaagacga taagcgaatt tactgatgct tggtctgata
    19081 atggaacagc tattcctcga ttattgcaaa acgctgcgct ttggggagaa gatttgtctc
    19141 aaataccgaa tgtgacagat acagttcaag aaatagctgc aaagatcgat caaaaaggtg
    19201 tccggtcagt attacaagaa atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca
    19261 acaatgaaat taaatcgacg agacagtgtg gtcgtcgcat taacccctat tccaaaacaa
    19321 acacaactga cgattgatca gcaaacgatc accactcttg aagatatccc gcaaggtcat
    19381 aagattgcat tgggtgattt gaaagctgga gacaacgtga tcaaatatgg ctatccaatc
    19441 ggtcatgtga cgacagacgt aactgccggt caatggctgc acactcataa tgtaaaaacc
    19501 aatctttctg gtgaattgga ttatcgatat gaaaaagatg tccatccaag tcattacctt
    19561 tttgagaacc gaacatttca aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat
    19621 gatttgtttt tagtacctac cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa
    19681 cagttcaagg aaaaacatcc agatctggga cagtttgacc atattacgat tttaaagcat
    19741 ccttatggct gttcgcagct tggaaaagat catcaaaata ctcgagaaat tttagcggac
    19801 gcagtaaatc atcccaatgc cggaggagtt ttagtatttg gattaggttg tgagaacaat
    19861 acagttcctg aattcaaaaa aattttaggt gaatatgatg aagaacgagt gaaatttcta
    19921 gtggctcaag atgtttacga tgagatcgaa caaggtgtgg ctctattaga agagctttta
    19981 acagcggcgg aaaatgacca gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg
    20041 aaatgcggcg gttctgatgg tctatcggga ataactgcta atcctttact tggtgcattt
    20101 tctgactact tgattgctca aggaggcagc acgatcttaa cagaagtgcc agaaatgttt
    20161 ggcgcagaac aagtattgat ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt
    20221 gacttgatca atgacttcaa acagtatttc ttgtcttacg gggaaccagt ttacgaaaac
    20281 ccatctcctg gtaataaagc aggtgggatc actacattag aagataagtc tttaggctgc
    20341 acgcaaaaat caggaagctc tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga
    20401 aaaccagggc ttagtttatt gcaagctccc gggaatgatc ttgtagctgc ctctgctctt
    20461 gcttcatccg attgccagtt ggtcttgttt accacaggaa gagggactcc gtttggctca
    20521 tatgtcccaa cggtcaaggt atctacgaat acaactcttt ttgaacgcaa aggtcattgg
    20581 atggatttta atgcaggcgt cttattagaa caaccaatgg aagtaatctt agaatcgttt
    20641 gttcaaaaaa tcatcgctgt agctagtgga gaagaaacga aaaatgaaca aaatgacgtt
    20701 cgagaaattg ccatttttaa aaacggagta acactttgat tttcataaaa cagtataaaa
    20761 agaaagaagg aagatttatg tttttatctg atgatttttt attaaaagac gattgggcga
    20821 aaaagcttta ccattcctac gcaaaaaaca tgcccattat tgattatcac tgtcacttag
    20881 atccaaaaga aatttacgaa aacaacaatt tcagcaatct gacagaagct tggttaggag
    20941 gcgatcatta caaatggcgc ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag
    21001 gaaatgcttc tgattttgaa aaatttttag cttggtgtca aaccgtacca aaaattatcg
    21061 gaaatccgct ttacagttgg tcacatcttg aattgaagcg tttcttcggt attgacttgt
    21121 tgataaatga agaaaatgca gagaaaattt ggacacaagc aaatgaaatt ttggcagctc
    21181 ctgattttcg ccgtcgggaa atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag
    21241 atgatcccgc agacgacttg cactatcatc agttgcttgc tcatgaagaa ccagatttga
    21301 aggttctacc ttcattccgt ccagataaag cactcaatat tgaaaaagaa ggatttaatg
    21361 catgggtcac actactggaa gaagcagctg accaaacgat caccacctat caagaactga
    21421 tagaagtctt agggcagcgg atagaatact tccatcaaca tggatgtcgt gtttccgacc
    21481 acgctttaga catcttacgc tataaagaag cggatgaaac agtattagaa gagatttttc
    21541 aaaaagcacg agctaacaaa ctattatctt cagatgaaat cgatgcttat cgtacagaaa
    21601 cactgataca tttgacccac ttctatcatt ctcataattg gacgatgcag ctgcacatcc
    21661 atgcttatcg taactgtaat acacaaatgt tggaaaaatt agggcccgat accggctatg
    21721 atggaatgaa tgatctttct ttgactattc ctctgcaaaa attattgaac cgtgcagaag
    21781 aaacggatca gttgccaaag acgatccttt attcattgaa tccgaatgac tatcctgcga
    21841 ttttagcttt gatgggctgt ttccaaaaag aacagaatgg aaaactgcag ttaggttctg
    21901 gatggtggta caacgatact cgagctggta tgcgcgatca attgacacaa tttgctgatg
    21961 gtagtgcttt ggggaatttt gtcggcatgc tgacagattc aagaagtttc ctgtcctaca
    22021 ctagacatga atatttccgt cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag
    22081 gagaagcacc tgaagatgaa caacttttag gaagtctagt tcaagcgatt agttatacaa
    22141 atgctaaaaa ttactttggc ttttttgcct aattgattaa tagtaacagt aacgaatcaa
    22201 aaacaggata gtgaaataac ggaatccgtt tatccacgtt ttagagaaga agacggacca
    22261 aatttgctcc gtcttcttct cttgctgttc tgcttcattg cctataaacc tttatgaaag
    22321 aagagataac atgcctacta tccatattgc cggtgattct actgcggcag aaaaagatga
    22381 aaacaagcgt cccgagacag gttggggaga aaaaatctct gcttattttt cacccgagat
    22441 ccagatcaat aaccaagcaa agaatggacg cagcaccaaa tcatttatcc aggaaggaag
    22501 gttagcccgt ctagcttcac agtttcagcc gaatgatttc ttatttgtac aatttggaca
    22561 taacgaccag aaaatccaag aagaaagagg tacgcttccc ttcggtagct atttaaaaaa
    22621 tctgcagata ttttttgaat gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc
    22681 tgtgacgcga cgagattact tagaaaacgg aacattgaat ccagatatac ttggagacta
    22741 tccaaaagcg atgcgtgcat ttgctgagaa acaccatatt cctcttttag atgtgttctc
    22801 aagatcacaa gaattgttcc agaccttctc aaaagaagag acaaaaaaat tctacctgca
    22861 tcttatacct gatacttgta aaaattaccc agaaggacta aaagacaata cccactttag
    22921 tccagaaggc gctgataaag ttgcccgaat aattgttgaa ttgataaaag aatcccgtct
    22981 gcctcttgct aattatttac aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc
    23041 gtgcccacga tttagatgtt cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc
    23101 acttgtccca tatccaattt gcaccacaaa aagcatttcc tgaacaactt aaattaactg
    23161 acatgacact tgggagtgct gcctattttg gtgaatactt ccaaaaaaac aatatcgaac
    23221 tttccatttt aggatgctat atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag
    23281 cattggcaac tttcaaacag caaattgctc tgtgctctgc ctatcaagcc aagatgattg
    23341 ctacggaaac cggtagtgtc tctgtcggtt acacaaaaga aaattttact gaagaagctt
    23401 atcagatcgc cagaaattct atcattgaat tagtcgctca tgcagaaaat tttggcgtaa
    23461 ctgttgctgt tgaagcaggg atcaatcatc caatctataa ctatcagtta gctaaacgtt
    23521 taatcgatga agtagcttca ccaaatttaa aaatcatttt agattgtgcg aatttgatgc
    23581 ataaagaaaa tcatgctgat caggaaaaag tgatccgagg tgccttggac aatttacatg
    23641 gttatattac agcgcttcat ctcaaagact atatcatgga aaatggaaag atccgcatgg
    23701 tacctgttgg caagggctgt ttagatttcc gcccggtact gcattatatc aaatatgagc
    23761 gtcctctaat gtacgccact cttgaagcta ctcctgagat ttatgttcct gaagcaatag
    23821 aacacttgca gtttatttac caagattgtt aaggagaaga ttatggagga acgaatacag
    23881 aaaagttatc aaaaatatca tgcaaatgct tttcagacat tgctgcatct ttatcaggga
    23941 aattattggc gttttgccat gtcaggactc ttttttatta tcaaacatct tccatcttgg
    24001 ttaatgccga tcgctattgc caatgtaatc aatgcagctt catcgaaaga ttcttctcag
    24061 ttgcaggcca tttatttcaa cgcttttttg atggcttgtc tgattggtca aaatatattg
    24121 acgaattatt ttcatgtaaa ataccatagc acttcgatcc gtcaagtaga agctggacta
    24181 agagcgaccc ttatcaagaa aatccaagaa ctatctattc cttatcaaaa agaattgcaa
    24241 tctggacgaa tccagtcaaa gatcatccgt gatgtagaag ctatccaaac gttgtcctct
    24301 caagtatttg tcagcggatt aaatatcgct gtcaatttat tcgtagcttt aggtatcacg
    24361 ctttataaaa gtcctgttgt tttcatgttt ttcttattga ctgttcctct cgccgcattc
    24421 gttactctct ttttccgtaa aaggatcaga cagtccaact cagacttcag gcaagaaatg
    24481 gaagagactt ctgcaaaagt gatcgaagtg atcgaattag caccgattgc tcgagctcat
    24541 gggttagaaa aacacgaaac aactcgctta aataagcatt ttactcaaat ctatgaaaaa
    24601 ggattccact tagatatcct gcaatctgtt ttcggatcag tcagctgggc tagttttcag
    24661 atatttcagc tgatttgttt gattttcact gggatattag ctttacaagg gcgcatccaa
    24721 cccggcgatg tcgtgatgta tcagacgtat ttcacgacga tcgtcaattc cgtttctgga
    24781 atgatcacgc tgattcctac gatttcaaaa ggcatggaat ctatcacttc tattggcgaa
    24841 ctgttgattg ctggcgatgt agaaacttat cacggtaaga aaaaaatcca acatttggat
    24901 ggaaattttc gttttgagga tgtttctttt ctttatccgg actcactcaa accgattatc
    24961 gatcattttt ctctagaggt gaaagctgga gaaacaattg cttttgttgg gccatctggc
    25021 tctggaaaat ctacactcct taacttattg attggattta tccagccgac ttcaggaaaa
    25081 atttttctag atgatcagcc tttggatgaa ctggatatgc gaagtgtgcg aaattattta
    25141 gccgttgttc ctcaaaccac tttgttgttc tccgcttcga tcaaagagaa catcacttat
    25201 ggcttgaaaa acgtatcaaa agaacgttta gatgaagtca tcgaagctgc gcaactttct
    25261 tcactgattg accagcttcc tgatggtctg gataccttag taggcgaaca tggcaacaag
    25321 ctgtctggtg gccaaaagca acgtatctcc attgcacgag cgttgatacg tcagccaaaa
    25381 atcattttgc tagatgaagc aacctcagct ttagataacc agtcagagaa aaaaatccag
    25441 caagccctga attacctgac agaaacaccc actactttta ttgtggctca tcggctttca
    25501 acgatcaaag aggcagataa aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt
    25561 acttacgaaa aactgttagc tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa
    25621 aaaataggag ctatgacaag acttttgtcg tagctcctat ttctgaataa acggtgttct
    25681 cctgccaact cctcggtcac aagtcacaat agtcatcaaa catgagaagc tgttttttga
    25741 aattgttcct tgtaactcag agttaaacgg taggctcacg acctcttggt aaatggtgtt
    25801 caagagacag cctatcggca ataagaagca attttgtcat cgctcaaggc cgaacgtctc
    25861 tttcacaccc tctgttgttt cataaaatag ttttattcgc tgtaaaggtc gcgaactggt
    25921 gtcatgatga tacggttcaa gtcattgatg attgtactga agccttgctc tttttgcatc
    25981 aagtcattga ttacttcttc tgattggatt ttcacagcca tttcttgtgc tttcattgca
    26041 tcttcgtcgc tgaactcttg tccactcatt tgtttttctt gtaattcgat ttgcatcgct
    26101 tggaagtctt tgaacagttt gtgtgcttct tcgtttgctt gtactttctc gtacgcttct
    26161 ttcaacgctt tgaattctgg taattcacgg atctcacgtt cgatttgatt cgcgctatcg
    26221 tagatgtttg acatgttatg ccctcttttc ttttagtagt tactctctat tgtaacatgg
    26281 ggttattcgt tttcaaaggg gctactctcc ttgatatttc cgccagaggt ctttagccgc
    26341 ttcaccaatt ccctgaacgc cttctttcac catatcgccg aagtttttca gcccttcttt
    26401 tgcttgttca ccatattgat tcaagttatc ttgccaattt ccagactctc cattagaatt
    26461 tcctgtgttt ccaacttgat ctgcagctac cacttgtcct cctgtggcat aggcatctgc
    26521 tacactaaat cctgtttttg aagtatacgg aaggatgcct tctgccgctg atttgaagac
    26581 tttcccgaca acatttccac ttgtcccttc caaatagtgc agcttgctgg attcttcgta
    26641 acccatccat gtcgaaatca ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc
    26701 ttttgtggca tcgaaattag tttctgtggt tcctgttttc cctgctatcg tataacctgc
    26761 aggattcgca gcagccgctg ttccatttga aaatgtacca agaagcatgc tggtcatttc
    26821 atcggctgtt tcctttgata tgacctgttt tggttttttg tttgtgttat cgacgatcac
    26881 cgctccagtc gaatcaacga ttttcgtgat aagatgcggc gtatacatct gaccatcatt
    26941 ggcaaatgca ctgtaagcac ccgccatgat caatggagat actccttttt ccagtccacc
    27001 aagggctaag ccataatact tatcagattt tgctaaaggc aggccgaatt cttctgcttt
    27061 atcatatcct ttttgtaaac cgatctcatg caaaagccat acagtaggca aattcaaact
    27121 ttgtgcaaca gcttgataca tcggtacttc tccttggtat gtcccgtcaa aattatgcgc
    27181 atcgtaataa ctttgcggtt cgtctttcaa gatactggaa ggcttgtatc cagcttccag
    27241 tgctggtgta tatacgctta atggtttgat cgttgatcct ggtgaacgac gcatctgtgt
    27301 agcaaagctg aatcctctaa agacatgatc tcctcttcgt cctactagtg cttgtacacc
    27361 acctgtattc ggatctaaag ctactgaagc agattggacc atggcaccat ctgaagcatt
    27421 tgctgggaat aatgcactgt tttgataagt agcttctaat tgcttttgat aatcctgatc
    27481 taaagctgta tagattttat agcctttatt catgacatct tcttcatcaa gaccatactc
    27541 gttaactgct tcatcgatca ctgcatcaaa ataataagga taacgataac cagaatctga
    27601 attatcgtat gtgtcattaa gatacgcgct gatatctgtc tggctttctg cttgttcttg
    27661 ttcttttgtg atttttccgt tttcttccat tacacttagt actgtgtttt tccgatcatt
    27721 cgcatttttt gggtgatcga tcggattata aataccagga cctttcagca ttcctgccaa
    27781 agtagcagcc tcagacagcg taacattcgt tgcatctact ccaaaatact ttctggaagc
    27841 gtcttggaca ccccataccc cgttgccaaa ataggcattg ttaagataca tggtcaagat
    27901 ttcttctttg ctgtacttct tttcgatctc gattgccaaa aataattcct tcgcttttcg
    27961 atcaaacgtt tggtctaatg tcagatacgc atttttggca agctgctgag tgatcgtact
    28021 tcctccgccc cctgatgttc cgccagacaa gaccattcgg actgctgcac gggcaatccc
    28081 tttgatatca aacccgtgat gctcgtaaaa attcctatct tctgtcgaga ttactgcatc
    28141 ttggatatag ggagaaatcg cgtttaattc tacatatgtt cctttttggg cgtacagtgt
    28201 gccagcttct tcgtttttct tatcataaat gactgtcgat tggcttaatc ctgattttaa
    28261 cgtttcgaca tttgcttgtt ttgctaaaat aaagaggtag atacttgtca ctaagacaca
    28321 gatcaaacca atcagcaaaa tcaatttgtt cacatgatat tttttccaga tgcgctttcg
    28381 ccatcgatgg aattgtccga gatatggtct gatccaacgc caaaaactga tcaaagcagc
    28441 ttttatcttt tctaaaatgc tttgaaaatc catttgcttc ttctcctgtc tatttgattc
    28501 aatcgtctta ttttaccata gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat
    28561 atgttttttt acgttagtgc aagtagagta acataagaat gaacagaaaa atgtaagttt
    28621 tttcttaaat atgttttaaa aatggtacaa ttagtctgcg attgcactga aaggagtaca
    28681 cttgtgaaaa tcacgatcac tttacctatg aaccatcctg aaacaacaat tcgcgacttg
    28741 cttgaaaagg aatggttagt tcctagaaag gttcgacact ttttgcgtat acgtaaaaac
    28801 gtttggatca atcaacaacc tgctttgttc catcatgaag taaagggcaa tgaccagatc
    28861 acattgttat tcgaagaaac agattataat tatcaagaag ttcaattagg agatgcgaag
    28921 cacatccgtg ttttatatga agatgagcat ttgattatag tggataagcc tgcaggaatg
    28981 aagactcatc caaatgaacc gacagaaaac agtaccttac tcaatcattt agctgcttat
    29041 ctcgacacta aacagcaacg accttacgtt gtccaccgct tggacaaaga aacaagcggt
    29101 gccgttttat ttgcaaaaaa tccatttgtc ttgccgatac ttggaagaat gttggaacaa
    29161 aaaatgatct atcggagata tcaagccatc gtatggggag aaattgccaa agatatgacc
    29221 atcaccaata aaattggacg agatcgccat gatcggagaa aaagggtcgt agatgataaa
    29281 aatggtcaga gcgccttgac acatgtcact gtcaacaaag tactttctga acaaacacaa
    29341 gtctattgtg ttttggaaac cggacgtaca caccagatca gagttcattt agctcataag
    29401 ggacatccga tcgttggaga ccctctctac caaaatagaa cagctgaacg actgatgctc
    29461 catgcattag aactgcacat gatccatcca tttactcaag aaaaaatagt cggtaaagct
    29521 ttacctggat tatgggaata gaaataaaaa agaacagagt cttatcagca gataatgata
    29581 agactctgtt ctttttgtgt aatttgtctg cttacttttg atgttcgtgt tctgctaaca
    29641 gcaaactacc gataatccca ctttcattcg gcagtcccca acgaacgata tattcactta
    29701 cttgaggtgt ttccatataa ccacccatca attcaacaaa ttgctgacgg attttttgaa
    29761 ggagatgatc ctgattcatt accccaccgc ctaaaataat cttttcaggt gctaacgtca
    29821 acgtatagtt gatcagtgct tgagcaatat aataagcctg aatagcccaa acaggatgat
    29881 cttgcggcag atcttgccct ttgatccctg tgcgtgcctc aatagacggt cctgctgcta
    29941 atccttctaa acaatcttta tgataaggac aagtaccttc ataatggtca tctggatggc
    30001 gtttcaccca aatatgtccc atttcaggat gtgcgatccc tgaaaaaatt tcttcattga
    30061 tcacgacacc tgcaccgatt cctgttccca cggtaaggta aatacaacta ttttttcctt
    30121 gtgctgctcc ttgcttcaat tccccatatg cagcagcatt gacatccgtt gtccaagcag
    30181 caggaatatt gtagcgttcc ttgattgtgc caagaaaatc gaattgtgcc cacccttttt
    30241 tgggagttgc caaaacgtat ccgtaattat cttttgtttt gtcgatacca atcgggccga
    30301 atgagccaat cccgattccc ttcaattcat aacgatcaaa aaattcaaat acctgatcca
    30361 atgtttcttc tggtgttgtg gtagggatac ttaatttttc taaaatttct ccaccatctg
    30421 aaaccgcaca cacaaatttt gttccgcctg cttctattcc gccatacatt cgttttcctc
    30481 ctcgaatccg attgtccgaa tctcataagg ttggattatt gggacaaccg cttgcttcgt
    30541 tggttcttca agcagattca atatgacagt ttttccattg tctttagtta tttccaattt
    30601 ttctaaatga ctagacatat tgaaacctct tactactact ttatcactaa acttgctgcg
    30661 tttcaaagct gtaattgcaa acgtttcact ttttatcgtt aaatattgtt gttttgaaat
    30721 caatgttcct tcatgatgtt tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc
    30781 atgcaaataa gtagagaatt tttcttctgg tccatgtagt tcaatgctgt aattgaaccg
    30841 atgctcacct agacactgtg cttctggtgt tggaaaatat ccccaatcgc ctagttctcc
    30901 cacactgcga agtagcgtca ctgcgatttg tccgtcttct gttacttcat attcattcaa
    30961 accaaagttt ccgactgtta caccgtactc ttcatcatga atattgacaa atgcttgctg
    31021 atgttgcgga ttcgtggggt tttcccaact tttagacaca tggtttgggc gcttcaccac
    31081 ttcaaaaata ctatctgctt cgtgatgttc cacatgtaac tttgtaggaa acaagacacg
    31141 taagcgatga tctttcatct gattgtcgag agtcgtttca aagtcgattt ttttactatc
    31201 ttttctgatt gtcatgattg tttttatttg aaggattcgt ttttctttgg atcgttctgc
    31261 ttttcgataa cgaaattcca caaccatctg ctgttctttt tctaaacgct cgtctgcaga
    31321 aacagggatt tccatttcct gtagaatact tatttttgct atttccggtg tatctactaa
    31381 tacttttact tcagagtttt ctttgttact ggataggatt ggctgatcac agaaaggttg
    31441 tttaaagata tactcatttc ctatatcgcc gatatcttca aaaatatgca gattattcaa
    31501 ctttcgtttg tttttgcgat cttccattgt aatggtacca tttttttcaa tcgtcaaatg
    31561 tagagggccg ttttcgatga ttcgtccact ctgatgaatc attgtttcct tttcttctgc
    31621 tttcgcttcc ccttctacaa gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa
    31681 tggtaaagtc actttgatca ttcttgccat atatggcaca cggaaacggt ctttcggcaa
    31741 atcataacca aattggacag tttcttcaga taaaatagct ggtatagtgg ccccactttt
    31801 tgtttctaca tgatacttac gtttaggcaa attttctaac tcttgatata gttgttcagg
    31861 tattccttca gcgaatcttt ttctttctaa ttcgatggtt atttctgctt caccagtttt
    31921 atccattcct gcagtattta caatgacaaa tggaaagctg tcttttggga atccggtcgt
    31981 atcgattgct gcggtcagct gttctaagga atcttgtgca agatactttc caacttcatc
    32041 tgctttttca aaacgaggta tcatttcccg atggacagaa tcgactgaac aaccgcaaat
    32101 actgtcgtga ggatgatttt gcattaatgt cttccaagca taatctaatt gatcatgggg
    32161 atagtttcca ctaacttcat aagccatcgt cgcaagtggt tctgtaatat tttctagctg
    32221 tcgctggacc ttggtattcc attgttttaa gtaaacccga gcagatgctg tattggctaa
    32281 agtataccag ccatccgttt cttgacttgt caattctcct tctactgagc ctaagtcttc
    32341 tggcacatct ttttgaactg cttccagata gtcagtaaaa ttagaatgaa taaactcgta
    32401 atctggaaac agttcatttg cgagatggat tgcttttgat atatcttttt gtaccggttg
    32461 atgatcaaca ccattcatca tcaataagtg gttcgtagag gcatattgtt ctgcatccgc
    32521 taatttttgc ttccaaaagg caagagctgc ttctttttct actggaatct cattcccgtt
    32581 gctataccaa ttggcaaata gcagaccaaa gattgctgtt tgatcaggtc ctttccacca
    32641 catctctgag tattgggaag aatagttttc tgcttccaaa acttgattat caaagccaat
    32701 tggttttaca ccacggccaa acgctgctgc tgaaatacca gcttgtttca ttaattgagg
    32761 cgtctgtccc atatttccaa atgtatcggg aaaatagcct aacatgacag gggttcccca
    32821 tttacggctt tcttccatgc caatcagcat atttctcacg ttcgattccg agctgataag
    32881 aaaatcatct tgcaagatat aaaatggtcc aattctcaat tttccttcat tgattgcttg
    32941 ttggattgcc tgtctttttt ctggccttac ttgaagatag tcatctaaaa taatcgtttg
    33001 cccatccaaa tgaaaactgt tgaaggacgg atcaacttca aatagctcta gtagatcgtc
    33061 tatcaattca atcagtcgca tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca
    33121 gtggctatga gaaatgatat atactttctt tttcatttac gatacctcct acttttctac
    33181 tctaatatca aagtaatcca tgactaattc gcaaaacatc atatttgccc aagaaaacca
    33241 ttctctcgta taattttcag gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc
    33301 tgcgtcagtt gctacaagta aattcaatat ccgctctttt tcagatttgt ctgacgttgt
    33361 cattccttcc atagctaatg caatcggcca aacgtatttt tctggcgtat gggaggatcc
    33421 aattcctttt gcgtactttc cttcatagaa atatggattt tctttactca acaatgttct
    33481 tcttgtttgc agataatctt cctcttgttc agaacaatat cccaagtaag gtgcggcgat
    33541 cagattgggc acattactgt catccatgac tgtggcgttt cccattccat ctacttcata
    33601 tgcataaatc gtttgccctt tttgattaac cgttcgtccg tgattctgaa tcccctcttg
    33661 gatctctttc ttcaatttct gtgtttgctg tacaatttct ttatcatcga gtatcgtttg
    33721 aaaaatttct tccacataac ctaacacgac caccgcaaac atattggatg gtaccagata
    33781 tccataacgg caagtatcat cgctaggacg gaaaccagac catgtcattc ctgtaaaagc
    33841 tgtttttgca cctcgcccgt cattgatcag cgtatcttct tttcttgtcg tgtctcgtac
    33901 aaatgtataa ggagagtgtt catgatcttg ctctgttttg aacacgtcca agattttttt
    33961 gataccttca ataaaagatt gattgaattg atcagttttt cctgtatttt tgtaaagaag
    34021 ataggccaac tgtattgggt agcataaaga atcaatttca tattttcttt cccagatcca
    34081 atcgttcatt tttgtatgat ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc
    34141 attcgcatat ggatcgatat tgatataaaa aaattgcttt ttgactaacc cgctgatcat
    34201 gtcagctaat tcctcatctt cttttgcaat cactaaataa ggacgaactt gtgcagtaga
    34261 gtctcttaac cacatcgctg gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg
    34321 ctttttgact gttgtcaaca gagtattggc aaatgctgct gtaaaattct ttgcccagtc
    34381 cgcatggata tccccacatt tttgtgtgat atcttccata aatttctgca ccgattttgg
    34441 tatatcttta taagccacta ataaaacctt ctttctattt gatatatctt taaagattat
    34501 acttcataca gccaattatg tctacgcttt caaaaaatat ctttttattt actttttcat
    34561 ccattatggt attatttgaa tatgatatat cattaagagg tgtttatatg aatcaaccat
    34621 tgtaccagac aatatttaat gatttgcaaa cggctatttt aactggtgaa ttacctgtag
    34681 acagccaact accaactgaa aaagaacttt cacgtaccta taaagtaagc agaatcactt
    34741 ccaaacgtgc attgactgaa ttagagcaat taggacttat ttatcgcgtt cgcgggaaag
    34801 gcagtttcgt taaatccgct tctccggaac agattcttgc ttctcctaca aaaacacgac
    34861 ggattctgtt tcttcttcca tatgtcgctg atttgtctgt tggtgatttt agcaagggat
    34921 tgaaccctgt gatgcaagat aaacagattg atgtcatgat gacgacgctt gactttctac
    34981 aaaataaaac agcaaaagag ctaatcaatg aatttgacgg attgatttat tatgctcttg
    35041 atacagaaca acatcttgac ttactttttg agctttcatt gaaagaattc cctgtcgtca
    35101 tattagataa aaaaatctat gagttacctt ttcctaccgt tctttccgat aatttccaag
    35161 gcggtgcgct tgctgcctct tatttgatcg aacagggaca ttcaaaaatc gcttatttgt
    35221 ttggtacgca gactcatcca caatccgttc gacagcgtta ccttggttac cttgaagcat
    35281 tggacaaagc tggtttgact ttccacactt cactggatga caaaagcgcg acattagatg
    35341 aattgctttc ttatatcact aagtatgaag taactgcttt tgtttgtgaa aacgatgttg
    35401 tcgctatcca gaccatgaat ctcttgagac agcatggtta tcatatccct gaagattttt
    35461 caattatcgg atttgatgat atccaagcag cagctcttgt tgacccgcca ctgacaacca
    35521 tcgcacaaga ttttgaacag ttaggtaagc ttgcgggaga tgctttggtc acttggttag
    35581 agacaaaaga tcgaccatcc gatagtaaat ttccagtttc attcatcaaa agacaatcaa
    35641 caaaggagaa ataaaatgaa tatcggtcaa atagatacta gacatgcaac agcgaatcag
    35701 ccaaatttct ctaatgggaa ctgccagcct tatactggcg ttccttttgg gatgaattat
    35761 tttgcaccgc aaactacgga tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt
    35821 tttcaaggct accgtcttac ccatcaacca agtccttgga tgggtgattt cagtcatatg
    35881 ctgtttacgc cgatcaatgg aaaactacag gagaacaccc ttttccatgc tcaaagttct
    35941 taccgcccag aagaaagtat attttgcccg actcatctgt cgatctgtca attacgttat
    36001 ggcatctgtt ctacattgat acctagcatg tatggcggaa tcttatctat tgattacagc
    36061 aaaaatgaca gcggtttact tttatccttt ccgggacgcc atcagctctt tgttatagat
    36121 ccttacacag tggaaggaaa aatcacacat tttgctggtt cagaagatcc tgatttttct
    36181 ttttatttta tattgagatt tgaatatcct ttaacaattg atgagttagc tgtttccaac
    36241 aaaaatagcg actcgatccc gttgtatttt gaacagacaa aaaaacaaac tatccgattt
    36301 gggacatctt ttatcagctc ggaacaagca gcttataacc tggaactaga acaaaaccaa
    36361 agcaaagaga cttaccttgc tcacagtcaa gaacaatggc agtcctattt tgatcgtata
    36421 cagctcacac accatgatca acaacaattg cggacgtttt atcataattt atatcgggtg
    36481 tttttatttc cacaaacatt ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat
    36541 acgactagtc gatctataaa acctggtgtt ctctatacaa ataatgggtt ttgggatacg
    36601 tataaaacgg tttatcctct ttattctttg attgctgtag aaaaatacga agaaatgctg
    36661 gaaggttttt tgaacagcta tagagaaagt ggctatttgc caaaatggct gtctcctgat
    36721 gaacgtggac ttatgcctgg gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa
    36781 gatatccgac gagacttgat gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt
    36841 caaagcaaac atccaaatta tggacgccaa ggaacagaag attacttgac atatggctat
    36901 gttcctaatc actaccacga atcagtcaat cacacattag actatgctta tagcgatttt
    36961 tgtattagcc aagttgccaa ggtactagaa gaagaggaaa tgacgaagaa atatcagcag
    37021 caatcattga actatcaaaa tatctttgac tatgagtcag gatttatgcg ttcaaaagat
    37081 aaagatggca agttcagaga accattttca gctaatcgtt ggggacaaga ttatgcagaa
    37141 ggaagtgctt ggcaaagcag ctttgctgtt tatcacgatt tttcaggact gatcggaaaa
    37201 tatggtggca gtgagagata taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg
    37261 tttgacccag gaggatatgg ttttgagatc cacgaaatga gtgagatggc cgcgatagaa
    37321 tttggacaat tagctatttc aaaccagcca agttttcact atccttactt gttcagttat
    37381 ataggacaac ctgaaatggc acagccactg cttaaacagt tgatgactca gaccttcgac
    37441 gattctccaa tgggttaccc tggagatgag gacaatggaa gtatggccgc ttggtatatc
    37501 ttcaatagtc tgggatttta tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg
    37561 ccattaattg acaaggctgt tttgcttttg tcaaatggaa aggaattgac gattgaagca
    37621 acgcctaatc ggccgcagca acaatttatc cataaaatca aacggatgga caaagaatat
    37681 acgaaattat attttaccca tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta
    37741 gggatcatcc ctcaccctaa gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac
    37801 tataattaac aagaggttgt gaaaaagctg tcctgcatca agtaataaga acagccaagc
    37861 aaaaatagat cctcatattt ttcgtttggt tggtcttatt accgcagatg caagcttttg
    37921 aacaccgttt attgagaggt tgtgaaatca gcgttctgac ctgagtatta gagagacaaa
    37981 tggcaaaata gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt
    38041 gaacaccgtt tagtggagag gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat
    38101 tttgtgaaaa tggctttcca catttttgca taaatttggc ttaataccga gaaactggct
    38161 tttgaactcc gtttatcgag aggtcatgaa aaagctgcct tgcctcaagt aataagaaca
    38221 gcccaaaatt agatttctag acaatttttt ataagttatt tcattacatt ggctttttct
    38281 tttatgattc tccactgttt tctcggtact ctttagggga tctgccgacg attttcttga
    38341 ataatttaga gaaatacgtg gtgttgttgt agccaatctc acttgctatc tcattgatgt
    38401 tttgattact gtgcaaaagc agttgtttcg ctttttccat acgtaaatgg ttcaaataag
    38461 ctgaaaaact ttttttcgtt tcttttttga acagctgtcc tagatacatg acatttaaat
    38521 gcaggttttc tgacacttct ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta
    38581 cgattacttt ttccacattg tcactgtact ttttctgtct ctgatgcttt ttgatgaatg
    38641 acagaagtag ctgctgaagt tcttgcaccg tttttgcctg atggattttt tcgattcctt
    38701 gtaaatattc ctcatcttcc agatcaatca attcccgttg aatctccata aacagtaaaa
    38761 aactggaata tcgtatatct tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat
    38821 cagtgatcat tttttgagcg acttccaatt gtttattttg cagcacgcgt ctgaaacttg
    38881 aaaaatcgat ggtttgatct tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt
    38941 tatctccata aaattgatgc aactgtagat tgtctttcgc ttgttggaat gtttcaggga
    39001 ttttgtccaa agaatctgtc tcttccccga tactgatcag ccattcctga tcaggaaagt
    39061 tttcttgaac aaaacaacag aagccatcaa cttcatctgc ctccaacaac aacgtgatca
    39121 atacacggtc tccgtaattt cgttgatagt aaaagatttg ttgccgttct tgcaaccatc
    39181 tattgataag agtatcatga gttcttgcca gttgaatcaa tactatccta tgctgcttct
    39241 cacttatttg tcctattatt tcttcttcac ttatttcatc caattcttca ttcaaccatt
    39301 gactgaataa cagttcttga tagatttctt gttgattttt ttgttcattt tgctgatcta
    39361 accgtgtttt gattttcttg aggctttcaa ccaattcgaa cttattcacg ggtttcatca
    39421 aataattcac ggcgcctaat tgcatacctc ctttcaaata atcgaattct tggtatcctg
    39481 ataaaatcat aaattcaaaa ttatgacgtt ctttttgagc cgcttcaata aattccagtc
    39541 catttatttc tggcattgtc acatccgtta ctactaaatc aatctgtcgc tgttcaagta
    39601 cagctagtcc ttctttggca ttctctgctg ttgctactat ttgaaagcct aaactttgcc
    39661 aatcaattat cttttttaac ccattcaaaa tcatgtattc atcatctacc aataacactt
    39721 gatacacgct catccctcct tgaatgtaat agaaacggtc agtccacctg tctcattatt
    39781 ctcaagcgac atataataac tgctgccgaa gctggcacgt aaacgttcat tcacgttttg
    39841 cagaccgata gaaccgtgaa gttccacttt aggatgagac agtttttctt caatctgttt
    39901 tagccgtttt tcagtcatcc cttttccatt atctttgatg atgatcctta cccgtttgcc
    39961 ttcctgcaag actttgacac ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt
    40021 aaaataattt tcaactaatg gctggatcac aaatttaggt acttcgatct tttccaaatc
    40081 aggatcgatc ataaaatgat aggctactcg attaggataa cgcatttgat acaaatagac
    40141 atatttttcg caaaagtcca gttcttcttt taaagtgatc gttttctctt gattcgtatt
    40201 gtttcgaagc aaagcggaaa acgcatacac aacatctgct aattcttcac ttccttcgct
    40261 gattgcatac attcggatat attctaatgt attatataaa aagtgtggat tgatctgtgc
    40321 ttgaagcgcc cgcatatgtg cgtcttgctg tttgatttct aatttgtaga tgtcttctac
    40381 aaactgattg atgctatcca acatttcgtt gataccgatt gaaagttcct tcagttcata
    40441 ttccgtgttt gttatgtcga tccgcgtctc taaattccct gctgctgttt gatccatggc
    40501 ctgcatgacg atagatactt gctgtgaata tcgtttgaat gttttataaa gaaagataag
    40561 cagtatattg tctaaaataa tgataccaat gatcagcggg gcaagatttt ttcccgtttc
    40621 gatttttaca ctttttttat ctagtacagc taatatacga taatcatcag acagttcttg
    40681 gtgttgaaca aaattgtttt tttccagatc gtcaatcggc aattgtgaat ttttcttcag
    40741 actctctgtg atgatcattt cttgtctttc aaacgtttct ttagctattt tattatcatg
    40801 gaatgtgtat agtcgatttg tcgttccaga aatcatgtat aaagagagtc cattgaatga
    40861 cgttagattt tctaaaatca tatctagttc tttcttttga aaaccaataa aaatacttcc
    40921 tgactcagct cctccttgtg tgataggcaa cttgatataa aaggcgtcta gtaattttgg
    40981 tgtccccttt tttatttccc cacctttgtt ttctctagaa gattcataat actccggtag
    41041 ttgattcaac acgatatata tcgcacttag ttcttcataa tttgcgtaga gatctttgat
    41101 ttgatttggg aaagaaacta attcatcggt actgttttgc tgttcgtata catacatcag
    41161 atactgatct atgggttttg ttaagtaggt cgtcacattt tcgatctttt cggaattccc
    41221 tacaagctgg tttttgatga tcctactcaa ggttgtttta tcattcagca ttctgcttgt
    41281 gctttgaacg gcatcacttg tcatgttttc tgcctgtttt tgattttgtt cccaagtatg
    41341 gatactaaaa ataacggtag cagtcatcgt tacaccgatc atgataaccg cgtatttccg
    41401 caacagacga tttagtaagg ttccttttga aaatagaatc cgaaacttat tcataacttt
    41461 ccaactgttt atctaattct tcacgccaat gtgttgtcat cgtaccattc caaaccgtca
    41521 aaagaccaat gacaccaaac aggatcaatc ctttgaattg ccaagtcacg cctaaaatta
    41581 taccgctacc aataattatt tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac
    41641 ttagctttag cagattagga acagagatcg tatattcact atctaaaatc atactgtatt
    41701 gataagtagc aaataggcag agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa
    41761 tgagcccttt gatttgaaca gataaatata aattgtaact caataaagca gtaccagata
    41821 aaaataaact aaatagcaga ttgcctctta aaaaatttct tttatatata ttccagcctc
    41881 tttttattgt gatttcttta tactcgaatc cgtacaaata aaatagttca ttgactgttt
    41941 tccatgccgc acctaatcca aagatgatcc cgccggcaaa tgtatatatc cagaaataca
    42001 aggttagttt tataatgacc cagatccgga taaataactc ttccaaaacc ttccctaaca
    42061 tatcttctcc tccaaacatt aagtttatac tttctcatta tacaaaaaaa ggttgggcaa
    42121 tcagcacctt gacctgatta ttagagaaac aaacggaaaa atagttcctc atattttgtc
    42181 gttttgtgag cgaataccga gggttagctg attgaacacc gtttaccaag agtttgtgaa
    42241 atagccgctt agtttcgagt agtaagaaaa attttgtgaa tatggctttc cacattttta
    42301 catatattta gcttaatacc gagaaactgg cttttgaaca ccgtttattc ggaacaagag
    42361 gttgtgacac gtcttttgtc acaacccctt tgtctttatt cattattatt cttgtcggaa
    42421 ctcatcatat tgtttttgca tttctttcaa taccttatca tagccagcct tgtccaaagc
    42481 gtctttcaat ttcggtaatg tttcatctgg atcaacagtc cctgtattca atccatctaa
    42541 atattgattc atgacattag aaatattact taattctgtt ttgacactgt cagtgttgaa
    42601 gctgaatcct aaaatcggtg aagtttctgc atcagcaatc gattgatcac gtttggcaat
    42661 catgtcatcc gtaatagact cttgtgtata tagaatcttg ttgtttcctg tattccaagc
    42721 agacatatgt gtatttggct gataaccatc tagcaatttg attttatcat ctgaaccatc
    42781 gactttttcc catgcttctc cctcgatccc ccaaacaagc ccattcaata attctggatc
    42841 actgttaagc agccctagaa gttctactga tttttcttta ttttttgaag tatttgatac
    42901 gacaaaattt gccatttgtg cttgagctgt agattttagt ggaacagtaa ttgcttttga
    42961 gacaagttct tgttttgctg catttgtcaa aattgtatcg ccataatcat acggtccttg
    43021 tgtttctcca cgcattagcc aagtatttcc ttctagtgga taatccttat tgctcgttgc
    43081 agcgtcactt ggaatgagtc cttgtttgta ccagctatgc attgtacgta acagtccgat
    43141 atacgtttca ttatcgtatt ggttgatgat tttcgaatca tctccatcca gatcaatagc
    43201 aaatggtaac gtattcccta aaggataatc aaagttccct tggactttga agccttgtcc
    43261 aatggcaaaa gctgccgtgt ttggttcttt ttcatggaat tccttcaaga ctttttctgc
    43321 atcagcgtaa gattggattc catcaattga aagatcgtat ttatctagta aagctttgtt
    43381 aaaagtaagt acttgttgag caaagacatt tccattgact gggaaagcat ataattttcc
    43441 attgaccaga tttcctttaa tatatgcttc atctaaatca ttataagctt tttcagcgta
    43501 cttaggcgct aattcagtca aatcagcaaa ggctcctttt tgggcattgg aaacatagtt
    43561 gttcgcaaag gcgatatcat aattttcccc ggaagaaatg atgacgttca ttttcttttc
    43621 gtaatcgccc cagccaatgt aattgatatt gacttttaca ccgatctctt tttcgattcg
    43681 tttgtttgct acttccatca attgatcgaa attatctggt ttatctccga tttgatacat
    43741 ctgcaaagtg tccgaattgc tagcttctgc ctggtcttta gaaccagaac ctccgcatgc
    43801 tgctaatgtt cccaacaaca acgctgaaac acctgtaaag gctagtttct tccataactt
    43861 catttttctt cctcctaatt ttatgattta tatttttgtt tctttattct tttactccgc
    43921 cgattgttag acctttgaca aaatgcttct ggaaaaatgg atagctgatc gcaataggca
    43981 acgtcgagat gactacgatc gccattctgg cagattctcc tggaactgag gctaatccgc
    44041 ctgtcaattg gcttcctgct cctgaatttt gtgtcagata ttgaatatta ctttggattt
    44101 tcatcaaaag atactgtagt ggaactagct tatcatcttg gatgtatagt aaagcattga
    44161 accagtcatt ccagtaaccc aatgcggcaa ataaactgat tgtcgcaata cctggaacag
    44221 ctaacggtaa aacgatctga acaaatattc gcagttcgct agctccatcg atccgtgccg
    44281 attcaataat cgaatcagag accgaacgtt taaagaatgt gcgcatcaca ataatattga
    44341 agggactgac agccattggc aagatcaatg cccaaatcgt atcttttaac tgaagaagat
    44401 ttgtcataac aagataattg gccaccatcc ctggtgagaa caacatcgta atcaaacaaa
    44461 aaacggtaaa aaaacgacgg aatggaaagt ttgaccgtga aatcgcataa gcatataaag
    44521 aagtagccgt gctattgatc agtgtaccta aaacagtaac aagtacagtg acgaaaagcg
    44581 cttggaaaat tttatcctgc atctggtcga acaagtacgt ataaccaaat atactgaact
    44641 tttctggcca aaaactgtac ccgtgagtcg acaatatgga ctcatcggta aaagagatgg
    44701 cgataacaaa tataaatggc aaaatacagg aaatagcaaa gagtgcaatc attatattag
    44761 agaaaaaatt agccgtctta ttgaaagagc ggacttggac tctctccact ttcttttttt
    44821 tcattttttt cctccttaga ataatgcaga atcgctatca aaacgtcggg cgatcgtatt
    44881 tgtgatcatc aacaagacaa agccgacaac tgattggtaa agtcctgcag cagccgtcat
    44941 accaaaatct cctgtggatg tcaggccatt gtagatatac gtatccaaaa cttgagtcac
    45001 atcatataat gcaccggaat tcctaggaat gttataaaac aggccaaaat cagctcggaa
    45061 aatgtttcct acggctaaaa tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt
    45121 cacatgtttg atctgctgcc atttgctagc tccatcaacc atagcagctt cataataagt
    45181 cggatcgatt cccataacag atgcaaagta aataatgctg ttataaccaa tccctttcca
    45241 tgtaccaatg aacaccaaga taaacggcca atatttcggt tcattatacc aattgacagc
    45301 ttctcctcca tgtccagtga tccactgatt gaatattcct ttgtcaggac ttaaaaaagc
    45361 gtaaacaaag taactgataa tgacccaaga tagaaaataa ggtagtaagg acatcgtttg
    45421 ataaacttta acgagtcgtt tatttctcaa ctcgctcata atgattgcaa atacgactga
    45481 gatcagcaga ttcaaaagga taaatgctac attatataaa attgtatttt tagtgatgag
    45541 aaatgcttga tccgaagaaa ataaaaattt gaaattttcc caacccaccc aaggactttc
    45601 cctcaagcta gccaagaacc catctgctga aatatgaaaa tttttgaatg ctacgacatt
    45661 cgccattaca ggtatgtaaa agaaaaaaat catccaaagc atacccggta cagccatcag
    45721 gacaagtgct ttataacgcc atagattcat aaaaaaatga ttgaacccct ttcgtttttt
    45781 catctaaaaa cccctttcga ttcattcgca acgtaattat agcgctttca ataatgagaa
    45841 taaataaaca aagtataggg aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt
    45901 tttggcctga gtattagaga aaaaaacggg aaaatagttc ctcatatttt gccgtttttt
    45961 gagctaatac cgagggtcag ctgattgaac accgtttatc agaggttgtg aattcagcgt
    46021 tttggcctga gtattaggga gatcgtgtcc ttactatcta actctgagtc acaaggaaca
    46081 atggggactg taacaaaagt cttgtcacag tcccttattc cgaacaaacg gtgttccaga
    46141 agtagcttct acggaaataa gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga
    46201 caagtctgct tttcagatgg cgctacaact actctgctta ttcttttagc tatccattca
    46261 attatttttc tctcacttgt tctagctctt ctttggtcat gggtcgatat tgccctttat
    46321 tcaaatcttt aggcagccaa aattttccca tacggattct ttttaaatat aagacttctt
    46381 ttcctactgc tttgaccatt cgcttaactt ggtgaaactt tccttcatgc aaaatcagac
    46441 ggataattga agtttctgtc tcttgatcta cttgatcaat ttggagtttt gccggcaatg
    46501 tctgctcatc gccatcaata atcagtcctt ctgcaaataa acggatatct tcttctgtca
    46561 ttataccgct aacctcagct agatattctt tctccacatg ttttttaggt gatagtaact
    46621 gatgggcaaa caccccgtca ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc
    46681 ggccgactgg aaaaagatct tcccgataat cctggtcttc caataaatcg attacggttt
    46741 gatcatgatt atcctgagta gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa
    46801 aatctttttg atacgtaatg atttctccta aataagtaac cgcatcttcg aattcattta
    46861 cttgcgcttt atcgcttttc accacttgtc cattgacttc gatcgttcct tttttgatta
    46921 atcctttgac ttctttgcgg ctgccaagtc ccatatctgc taaaaactta tctaaacgca
    46981 tgcgtttccc ccatttcaaa agagcatcaa tctagctctt ctgattcact tattttattt
    47041 ttaatttatg tcgtaaacgc gctattcctg gtcctagtag tctttctgcc aagcggattt
    47101 tcaaagctaa ataaccatac actaaagccc ctatacctgc tactacaaga atcaacaata
    47161 gagactggaa tttgctatct tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg
    47221 aagccaaaag cataatcaag gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac
    47281 ttggtttaaa gcgggctact tcatggattc tctttaagat caaggtacaa gacacagcaa
    47341 atccgatcat tgtcgccaat aaagggccgt atacttcaaa taaacgaatg gctgggtatt
    47401 gaagaaggag tttcactaga aacccaataa ccaaataatt aattgccgcc ttgttttcaa
    47461 acattccttg cagcatgttg gaaactagca tatatagtcc taggaagagt cctacaaaac
    47521 ttgcttggat cagtacatta cttcctagag aatccggtgt ataaaataat gtatttagcg
    47581 gataggcaag taacataaca ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta
    47641 aatttccgct tgtcaatttt gccagaccta ctcgatcttt caacgtaaca gcttctgtaa
    47701 tcaacggtaa cccagtagac gcgatcgatg ttgccaatgc aataactacc atcgtcaact
    47761 tatctggatt ggcactaaaa atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg
    47821 tggatgcaga catgatcttc ataaaagtga actgatcgac taatttgaag atcgttaccc
    47881 ctgaacccac aataataaac ggaatcgctt ctttaacggt atctaacaac aattccttcg
    47941 ttgcaatatt tattttgttt tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt
    48001 tcttcaaaaa atacaaaagg acaagaatac ttgctagcat accgataaat gccgcgaaag
    48061 ttgattgcgt gaccgccgtc acatagtcac catccatgac tttcatgatg atgaatgtag
    48121 ccaatagcat ataaaaaata cgtgccacct gttctacaat ctgcgacagc gcataaggca
    48181 tcatttcttg attgccttgc aaataccctc gtatcacact catacaagga aaaaccaata
    48241 cagcgatact caaagaacgc atcgttggaa tcagttcttc tccgccacca gaagcatgag
    48301 ctagccaagg agaggcgatg tacatgaaca aagcaaacaa caggcctaac ccgcccatca
    48361 tctgtaatgc acggataaat aatcgtcgtg aagtgccata ttcattcaat gaattatagc
    48421 gtgcagtttg ttttgcaatc gcagcaggta ttcctgctgt agagatcagt agaaacaatg
    48481 catatatatt gtatcccata ttgaataatc cattggcagc cttagcattt tcgcccatcc
    48541 aagcatacca gggaatgata tagacagcgc ctagcaatct tgaaatgata ttactggcgg
    48601 tcatccaagc agagcctcgt gccatttttt cttgcggtgt taattgatct aatgatggtt
    48661 ttctttgatt atccatcggt cagattccaa ctttctacaa aacattacta tcattttaat
    48721 tggtaaaaca gaaactggca atcgatttta tataactttt ataagaacaa ttgttttttt
    48781 gaattcggtt tcgttttttt ggtaaagtaa agaaatatac agccttttat ggctaacatt
    48841 tataggagat atcaatgaca caagaaataa aaaaactacc cgttatattt ttaggtcttt
    48901 tctttatcac agttggattg aattggttct tgctccctca cgatatagct tccgccggag
    48961 tgggcgccat cggacattta gttgaaacgg ccttttctat ccaacgctca gttactgttt
    49021 ggagcatcaa tcttatgatg ctgcttctag ccgctgtcct attaggaaaa tcagtatttt
    49081 ttaagactgt agcgggaagt ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg
    49141 aaatgatctc ctcacatttc ttttcactga tttcaggaag tcttttgttc agtcttgggg
    49201 tttacacatt gtacacagtc ggggcctcaa atggcggtat aacgataccg ccgattattt
    49261 tccacaaatt ttttcggctt ccaatgccgc aaggactttt acttaccaat agtcttatcg
    49321 tctttttgaa ttattatgtt tttggattgt tggagacact attcgttctc ctatctatta
    49381 cagtcagttc attgtttatg aaaatactca tccgcttgtc ccctgtgtca agaaaatttg
    49441 aataaagctg gattttgtca tagcggaaac aaacgatata ttaaaaagag tgtgctataa
    49501 taaaccaaga aattgaataa agcgagggat caatcaatga gcttctcttt agaagacatc
    49561 cgtcatttac tattaaaaga aaatctatta aaagaatttg tttcaacaag aggctggcat
    49621 cttgatgtac cagaaaaagc tgaatttctt cagttaagtt atgattcaag aaaagctgat
    49681 gcttctactt tgtttttctg taaaggaatg aatttcaaag aagaatattt ggattcagca
    49741 atcgaacagg gtattcaata ttatgtatca gaacaaccat acgaaaattc agcagtagga
    49801 atcatcgtaa cggatatccg taaagcaatg gcgcttcttg ctatggcttt ttacgactat
    49861 ccgcaaaata aattgaaagt gatcggattc actggaacaa aaggtaaaac aactgctgcg
    49921 tactttacaa aagcaatctt ggatcacaca acaaataaaa aaacagcatt gctttctact
    49981 atgaatacaa cgttagatgg caaaacatat ttcaaatccc atttgacaac gcctgagtca
    50041 ttagatttat atcgtatgat gtcagaagca gttgaaaatg gtatgactca tctagtgatg
    50101 gaagtttctt cacaagctta caaaacacaa cgcgtatacg gcttgacttt agatgtcgga
    50161 atcttcttga atatctcgcc tgaccatatc agtccgatcg aacatccgac atttgatgac
    50221 tatttctatt gcaagcgaca attgatcttg aattcaaaaa cagttgtttt aaatcatgaa
    50281 agtgactatt ttgatttact tagggaaaca gccgatctat tccagattcc aacgatcact
    50341 tatggtcgtt cggaagaaag caattatcaa gtgatccgtt cagataaagg tactcacggt
    50401 tttactttat cttctcatga agatcgctta gctatctgcg atactgctta tgatattttg
    50461 ctggctggag gattcaacca agaaaatgca gccagtgcga tcattgccgc agcactaaca
    50521 ggtgcctcca gtcaagatgc acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg
    50581 gatcaattga tccaatccaa tggagcgcat gtctatgtgg actatgcaca taattatcta
    50641 agcttgaaaa cattgctgaa atttgccaaa aatgaacatc cagatggccg tgtaattgtt
    50701 gtattaggca gcccaggaaa caaagcaatc tcccgtcgac atgattttgg aaaagtgcta
    50761 tcagaaacag ctgacatcgc ctttttgacg gcagatgacc cagcatttga agatccgaaa
    50821 aaaatcgcgg aagaaatcaa tgaagcaatt actaatccag atttgatcgt tcattatgaa
    50881 atggatcgtc ctgaagcgat tcgacgcgct ttagcagaaa gcgctccgca agattcagtc
    50941 gttattgcgg gaaaaggcgt ggatccctat caaaaaatca atggtgtaga tgaaccttat
    51001 gaaggggatt atgcaatcgt gaagcggttg attgaagaat aatggtattt atatactagt
    51061 ggtttcccat ttctaagaaa aaaagggact gtgatttttt gtcacagttc cttttttctt
    51121 agaaatcatt ttaacttttc actagctaat tctgctgcct tttctctttc ttcatttaat
    51181 aatttattat catagaattt gataaatggg aaccagataa tgaatgcgat gattgcacaa
    51241 atgactgcta acacagcagc tttccaatca ccaccactac caacaaatgc tccgatcccg
    51301 actggtgaag gccacggcat ctgtgcaagc atcggtttga cgatttccag ccgaatggca
    51361 aaataagcga gtgtagcaga agccatcgga gctaagaaaa acggaaccgc taaataggga
    51421 ttgtagacga ttggcatccc gaaaatgatt ggttcattga tattgaataa tcctggtaca
    51481 agtgaggctt ttcctaacac tttcagctga tcagatttcg cgaggaatgc aataaagatg
    51541 atcaatccta aagtcgcacc tgatccacca acggttacat aagaattgtt gaattctcct
    51601 gccaacggat aatttgcgcc ttgtgcgtta gctgccatat tagctaatac gatcggggtc
    51661 aagaaagaag tgatgatatt cgctccatgg atccctacga tccacaatgc atggatcaag
    51721 aaataaatca ccatgacacc aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg
    51781 atagcaatca ttttgaagat atccgttcct agtgcaacta ataatccatt gatgatcatc
    51841 accacaaacg caatgacaaa tgttgggatc agagcagtga aagaacgaga aactcctggc
    51901 ggaacaacat ctggcatttt tatgacccaa tttctcttga cacacataca atacaattcg
    51961 accgcaataa tcgacataat aatagctgta aagattcctg aagttcctaa acgttcgaca
    52021 aaagagccca tcctaatacc atttactaca gtttctgtct cattgataga agcaatcaag
    52081 ctgattttac catcagtcat gatcaattca gggatacaca taaagaatgc aaaaacagat
    52141 agtaatgccc ccgtgagcgg attaacattt aatttttgtt catctcgttc aattgacgtt
    52201 aattcataag caaacacaat ggcaaagtaa atagataaaa tccccatcgt cattgtattg
    52261 acgatcatgt acaagtcact aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat
    52321 gggaacggta atggcaaaat atttaaaacc aaaaacatcg agcctacaat cgtgaaagga
    52381 atagaagcca tccccgctgc catgacagcc cgaacgattt taagttgcgc aattttcccc
    52441 ataggtccca tcaggtattt ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat
    52501 ataacgcttt ttcatattgt ttaatacgga tatactgttg gtcttggttg agtgaaattt
    52561 tctttaaacg atactgtata aatgcactgg caaaaatacc gcttacaaca agaatgaaaa
    52621 caaataactg tcctccattg ttatttgcca taaaaggata caagaatgta aatcctgagg
    52681 taaacaacac tggaatcact aataaattaa agacactctg gaacaaaaaa taccactttg
    52741 tccatggaac gttcgtttgg tgttttcgat aaagctttac ttgttctcct actgcaggca
    52801 aaatagctaa aatcagaatc atcggtaaac tacttcctaa acttttagct gatagaagca
    52861 gaatcatcca ttgcatgttc atgaaaaaga aaaaggcagt caggtaacgt acgattagat
    52921 aacgattgaa atacatgttt ttcaaactaa gttgcttttt ttctaattcg attttccttt
    52981 ttactgtatc ctgcacaatg atccttcctt tctatttatt tttttgatac aaataattca
    53041 tttcctgtgc aacttccaat aatgtcatcg tcgtcatcag atgatcttgt gcatggacca
    53101 tgataatttc catttctatt tttgtcccgc tggcatattc tttcagaagt tgagtttgtg
    53161 actgatgcgc atgaagaatc tcttcatttg cttgtcgcaa cttctcttct acttcttcaa
    53221 acatctcttt acgcatcgag cgaaatgctt catgtatcag tgtccgtgca tttccgctat
    53281 ggaaaatgat atcaaaagaa gtcacttgta gtgtttcact gtttattttt tcagccatct
    53341 gttttcctcc ttattcgatc agtttgataa atttactgct gaaattctca aaaataggtt
    53401 cagctaagat ttcctgctgt acttttagct ggtcaactaa cctaacgatt gctttagtca
    53461 cgaccgtaat tccttcattt tcgacataag aaggcgaaac taaaaaaaca aaatgaattt
    53521 cttgatattg atcccactgc atcccagaag gaatcaatgc aacggctacc tttgtttcga
    53581 ttccaactgg aacagcggga tgtgggactg ccactgtatc actgaatatg atttgtccca
    53641 tattttcacg ttgctggatc tgctttcgca tttctcttat atatccttct tcttcattta
    53701 tgctcagctt ttgcagcaaa tcatgaagaa tttcttcctt tttcggttcg tacgtataag
    53761 tcttgaaaaa tttttcagac aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa
    53821 atgctggtat cggtctatct gaggaatgat agggtataga ttctccaact acctttcgta
    53881 ttttacgaac atcatcttca ttcaaaaaaa tactgacatg taaaactgga attttgaaaa
    53941 acattgtcga aagatcaata gaagaaataa tcaggtcgat tccttttaaa gttgtttcat
    54001 tgatctcata atagcctttt acacttacca ctgtaatatt tttaccgaat tcactgacta
    54061 cgcgattctt taatagttgg gcactgccgt aacccgttgc acagataatc aatgcatgta
    54121 gtttatgcgc agctctttct ttttccaatg ccgccatgag atgcaaagcc aaataggccc
    54181 attcatcttc attgatggta tagtttttca aagccggcat gttgctgaaa tgccttttta
    54241 ctgcgtcaaa gactttggga ttttctttct ttatctcctc agtcaatggg ttctcaatgc
    54301 gaatacctcg gctcaatcga atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa
    54361 gctggagatc ctctactaat gaaaaatgaa attcctgaga caatcttttc agaactttcg
    54421 ctaattcctt tgatagttcc tgatcatttt gattttcttt gtgattcgac ttagccatga
    54481 gatgtaatgt caaataagca atttcttctt cgggaaacga tacacctgcg attacctcaa
    54541 tacgttgaac gatccgctgc gccacttgat actctactcg cttagaaact tcttgttcga
    54601 tgcctaattc cttgatttca aacccttctc ggagccgttt gatccccaaa gccaagtgta
    54661 aagtcagatt ctgtatgata aaatccgaaa cttttaactt agcttctctt gtttcatcga
    54721 gaatgataat gactagctct tcaaaactga tgtctgggaa aaaacggctt tgccctaaat
    54781 attctttcaa tgaatttcca taatggtttc caaaaaaagt atccatgata aaatgccgtc
    54841 gatttctttc ttccccttcg atccatgtcc cttgaccatg cttagaaacg atttttagtg
    54901 aatatggaat caatcgctcc ttgatttctt gcatgtcctt tgtcaaactg gaacgactga
    54961 tataaagctc ttctgccaaa tcatccataa aaagaatggc atcttccaaa agcaattggt
    55021 tcaatatata cttttgtcga tcttcggact cataaaatcc ttgcggttct ctagcatatc
    55081 caggtactat ttcttgccga ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca
    55141 gttggtagcc ataacctggt ttagcaatga tcttacctcc gtttttttct actaactctt
    55201 tgatccgctg caagtaatta cggattgtcc gatcagataa taacaattca gaagctaaac
    55261 gttgactggt gacatactcc ttcttgtgat caatcaaata tctcaacagc aatttttcct
    55321 tctgtttcat tatcatccac tcctattcca tcatatgttc tcttcgatca cctctgctaa
    55381 cttctggatg cctgtaggga ttgggacata cgcttggaaa gggatactaa caacaggctt
    55441 tccaacagat tctcctaatt ttttgaattt atccaaaaac atcgtcgttt gcgggctgat
    55501 cagaaataaa tcaaaatcac tattcttaat catattatcg ccttctgtag ctgaaactgc
    55561 atctacgagt acctcttctc ttttttgctt aaagaaatcc gttgtctttg aggccatcat
    55621 cgaggatgac attcctgccg cacaaataat caatgctttt ttcataaatc aatcactcct
    55681 tttattttta taaaccaagc atatcttgta agcgttttct attcaaaata tatatttccg
    55741 tagcattgcg gaaaaaatgt gtatcatatc ttgaataata atttctggca ccgtgatata
    55801 ctagtgatag aattttttca ggaggggatt tagtgagtat cacagtgaat attttgtata
    55861 caagtacaaa tggacaagcc agaaaatttg cagaagaaat ggtcgaaaga aacattgtca
    55921 aagcgattcg tgcagaagaa ggaaacgaga aatatgacta ttactttcca ctagaagatc
    55981 cagaatctct tttactgatc gaccgttgga aagatgaaga agcaatcgaa aagcatcaca
    56041 aatccgaaat gatggctcaa ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag
    56101 tcgaacgttt cactgattta ccgtaaaaag atacacatgg aatgatagca atttatcatc
    56161 catgtgtatc ttcacttttt ccttattttt tattcgatct catctaatga ttcaaaccgt
    56221 gtttttctct tatttttcgg ataagtattt cagtcacccc aatatacatg attcctaaac
    56281 ataccccaag gatattctca aaaatgcgga tcgttactgc tcctggaacc ccgaataaac
    56341 tggcagtgat tgccaaagca ccaaaagaat taaaaactgt tttatatcta taggtagaac
    56401 aaacacctaa agctagacca cctaatatac cgacccagtt aaaaggaata aattggctga
    56461 taccaataaa taaaacacat ccaatcaatg agccaatgat tcggtctact gctcgttctt
    56521 tgaaaccaat cgacatcaat ccatagctag atacaataga agaaaatgca aaccctgccc
    56581 acatcaatcg ctgaaaaggg acatactctc ctgcaacgat caaaagacta atgccaaatg
    56641 catagatgag catccaaatt ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa
    56701 acaagctttt gtctttgttc ttttctcgat gttttctgta aaggagaact gaaaaccaac
    56761 aaaaaaacaa aaataataag ctacttgttt gtgtaaagaa attcttgttc aacgaatctt
    56821 taggtaacga ataaacaata aagagatatg aaaagccgta caaagaagca ttccccattt
    56881 tgggatcact agcggttgcc attaatatgc tgcttagtaa aataaaatga atcaacatgc
    56941 ccataactga ccatttgatc agctggacat acggtgctac taatagtgag aacatgacga
    57001 ttgctaaacc tatgatcgaa tgggaaatct tataaccaaa gtcaacaaaa cgaatactca
    57061 tcaacataca gaataaaacc acagcgtatg gtttatgctt cgattcaaat aatgttgtaa
    57121 ttataatgat aaaacaaatg gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac
    57181 aaatatacat gcacttttct tttttagaag ctgcttctcg tattttttgt tttaaaataa
    57241 acggatctag ttgtagagac tgataaaaat ccacctgttg tcgtcctttc tttttacttt
    57301 tattttttac agtcatctat gacaggttgt aaatactatg gaacatcata tggcgttgtc
    57361 attttcttgt caactatttt tcctattcat gtttttataa aaaaacatat cgttttcttg
    57421 tatgattaaa tcaccacaaa ataaacaact gagagaacga tatgctttat gaatggttct
    57481 atcaaaaaaa ttctgagatc aatagacaaa aatttgatga ttacagaggt ctcttacgaa
    57541 accttacaga agaaaaaaac attgatcgtt gctgcagttc tcttccctgc tccatgtgtc
    57601 tgtagaaatt gtggttctgc tgtggtagat ggaaatagga aattaatggt ggtgaaaaac
    57661 aagaagaagg aaaccattgt ccactttgaa taatataatc atatgccaat ggttatacgc
    57721 ctaaaaaagc agcgctatac ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat
    57781 tttatccgtc caaggcactc gatttcaaat catgtcagac ataaaatcac ttctttactg
    57841 actgaaaaag tgtcgttatt ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt
    57901 attcgcacat tgaaagagtt gagaagctat ttaccaaagt cttccaaaag aattctgtct
    57961 tgagtgttga gggttgtgaa tttcgttctc acgtttccgt tgaggataaa ctgagtttta
    58021 tttccgcgga tggcgagaca gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc
    58081 tcgattaaca aactatttcc ttagctgcac taatcctaaa gaaatagaat tcttagttac
    58141 agacatgaac gccacctact ttcagctcac caaacatgtt ctaccaaatg cgaaattggt
    58201 gattgatcga ttacttggtt tttccacgcc tttcaaggag gcgtaacctt tattcacgag
    58261 ttggttgaag ctttccgaga caaaagaccc gacttgtttt tctccttatt gacaaagagc
    58321 cattaaaact agagaaaaaa ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa
    58381 gtattaccca ataaacttga gtcattaggc aaaaaacact gcgaaactca agaatgattt
    58441 tcgcagtgtt tttgtatatt ttttattaac tagtattact acaaaggttt atttttcact
    58501 tctcaacgca gcacaaaatt gtctttactt atttactggt tgggttcaac cttctctact
    58561 ccgatactaa tatttgtttg tatacccctt ctaaaatcgg tagtttccat tcaattgatg
    58621 ggtactagtt gattttaaaa actatgctta ttcaattttt tattttagct catatatttc
    58681 gtttctttct aaattttata ctgatgaaaa caagtagcac acccaatatt gacaatataa
    58741 actggctaat gatggtttct ccagtttttg gaagatgctt atttccactg cttgttggat
    58801 tgtttcctct tatatctgag ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg
    58861 ccacttcttg ttctttttcg atcttgaaag ttactggtgt cgcatccaat tcataccccg
    58921 ttggcgcttg agtttctacc agctgatatg ctcctggtgc taagccatct atcgccagtt
    58981 ttccatctgc tcctgtggtt agacctgact gcagaacggt tccattggca tcttgtaact
    59041 caaaaacagc tccttgcagg acttctccgc tttggtcatc gatctttgtc aacacgacac
    59101 cgcctggtgt aagtcgattt tctttcgtca attctaccac cgctgtctga cttctttcga
    59161 tctcaaactc gattggtgtc gcatccaatt cataccccgt tggcgcttgg gtttctacca
    59221 gctgatacac tcctggtgct aagccgtcaa tcgccagttt tccatctgct cctgtggtta
    59281 gacctgactg cagaacggtt ccattggcat cttgtaactc aaaaacagct ccttgcagga
    59341 cttccccgct ttggtcatcg atctttgtca acacgacacc gcctggtgta agtcggtttg
    59401 ctttcgtcaa ttctaccacc gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg
    59461 catctaattc ataccccgtt ggcgcttgag tttctaccag ctgatatgct cctggtgcta
    59521 aaccgtcaat tgccagtttt ccatcttctc ctgtagttag accggtttgt agcgtttctc
    59581 cttctcggtt ctgtaactca aaaacagctc cttgcaggat ttccccgctt tggtcatcga
    59641 tctttgtcaa cacgacaccg cctggtgtaa gtcggttttc tttcgtcaat tctaccaccg
    59701 ctgtctgact tctttcgatc tcaaactcga ttggtgtcgc atctaattca taccctattg
    59761 gcgcttgagt ttctaccagc tgatatgctc ctggtgctaa accgtcaatt gccagttttc
    59821 catcttctcc tgtagttaga ccggtttgta gcgt
//
LOCUS       DACDAF010000008        56383 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.008, whole genome shotgun sequence.
ACCESSION   DACDAF010000008 DACDAF010000000
VERSION     DACDAF010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56383
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.008"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            330..1175
                     /locus_tag="IVZ69_000434"
     CDS             330..1175
                     /locus_tag="IVZ69_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP8182553.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="IVZ69_000435"
     CDS             1456..2676
                     /locus_tag="IVZ69_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HAP8182554.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="IVZ69_000436"
     CDS             2673..5393
                     /locus_tag="IVZ69_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP8182555.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="IVZ69_000437"
     CDS             5377..6321
                     /locus_tag="IVZ69_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP8182556.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="IVZ69_000438"
     CDS             complement(6390..7400)
                     /locus_tag="IVZ69_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP8182557.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="IVZ69_000439"
     CDS             complement(7580..7924)
                     /locus_tag="IVZ69_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP8182558.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="IVZ69_000440"
     CDS             complement(7917..8351)
                     /locus_tag="IVZ69_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HAP8182559.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="IVZ69_000441"
     CDS             8489..9226
                     /locus_tag="IVZ69_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182560.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="IVZ69_000442"
     CDS             9219..10430
                     /locus_tag="IVZ69_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182561.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10637..11416
                     /locus_tag="IVZ69_000443"
     CDS             10637..11416
                     /locus_tag="IVZ69_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HAP8182562.1"
                     /translation="MEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAAL
                     SREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLKT
                     MLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHGD
                     VNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDEM
                     LEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="IVZ69_000444"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="IVZ69_000444"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HAP8182563.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="IVZ69_000445"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="IVZ69_000445"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HAP8182564.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="cpaF"
                     /locus_tag="IVZ69_000446"
     CDS             14132..15061
                     /gene="cpaF"
                     /locus_tag="IVZ69_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component"
                     /protein_id="HAP8182565.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="IVZ69_000447"
     CDS             15018..16067
                     /locus_tag="IVZ69_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HAP8182566.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="IVZ69_000448"
     CDS             16064..16342
                     /locus_tag="IVZ69_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HAP8182567.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="IVZ69_000449"
     CDS             16317..16787
                     /locus_tag="IVZ69_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HAP8182568.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="IVZ69_000450"
     CDS             16804..17106
                     /locus_tag="IVZ69_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182569.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="IVZ69_000451"
     CDS             17123..17494
                     /locus_tag="IVZ69_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HAP8182570.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="IVZ69_000452"
     CDS             17466..17825
                     /locus_tag="IVZ69_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182571.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="IVZ69_000453"
     CDS             17997..19004
                     /locus_tag="IVZ69_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP8182572.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="IVZ69_000454"
     CDS             19029..20213
                     /locus_tag="IVZ69_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HAP8182573.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="IVZ69_000455"
     CDS             complement(20650..22233)
                     /locus_tag="IVZ69_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP8182574.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="IVZ69_000456"
     CDS             complement(22811..22954)
                     /locus_tag="IVZ69_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HAP8182575.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="IVZ69_000457"
     CDS             complement(23177..23656)
                     /locus_tag="IVZ69_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP8182576.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="IVZ69_000458"
     CDS             complement(23729..24013)
                     /locus_tag="IVZ69_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182577.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="IVZ69_000459"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IVZ69_000459"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="IVZ69_000460"
     CDS             complement(24357..25643)
                     /locus_tag="IVZ69_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HAP8182578.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="IVZ69_000461"
     CDS             25781..26452
                     /locus_tag="IVZ69_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HAP8182579.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="IVZ69_000462"
     CDS             26418..26906
                     /locus_tag="IVZ69_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HAP8182580.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="IVZ69_000463"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="IVZ69_000463"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HAP8182581.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="IVZ69_000464"
     CDS             27867..28631
                     /locus_tag="IVZ69_000464"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HAP8182582.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="IVZ69_000465"
     CDS             28864..31077
                     /locus_tag="IVZ69_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HAP8182583.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="IVZ69_000466"
     CDS             31088..31534
                     /locus_tag="IVZ69_000466"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HAP8182584.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="IVZ69_000467"
     CDS             31705..32964
                     /locus_tag="IVZ69_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HAP8182585.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="IVZ69_000468"
     CDS             complement(33053..34000)
                     /locus_tag="IVZ69_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP8182586.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="IVZ69_000469"
     CDS             34394..35686
                     /locus_tag="IVZ69_000469"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HAP8182587.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="IVZ69_000470"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="IVZ69_000470"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HAP8182588.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="IVZ69_000471"
     CDS             37579..38454
                     /locus_tag="IVZ69_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP8182589.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="IVZ69_000472"
     CDS             38720..40603
                     /locus_tag="IVZ69_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP8182590.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="IVZ69_000473"
     CDS             complement(40678..40962)
                     /locus_tag="IVZ69_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP8182591.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="IVZ69_000474"
     CDS             complement(40952..41686)
                     /locus_tag="IVZ69_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HAP8182592.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="IVZ69_000475"
     CDS             41815..42438
                     /locus_tag="IVZ69_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HAP8182593.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="IVZ69_000476"
     CDS             42630..43751
                     /locus_tag="IVZ69_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HAP8182594.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="IVZ69_000477"
     CDS             43758..46886
                     /locus_tag="IVZ69_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HAP8182595.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="IVZ69_000478"
     CDS             46905..50099
                     /locus_tag="IVZ69_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP8182596.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="IVZ69_000479"
     CDS             complement(50245..50952)
                     /locus_tag="IVZ69_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP8182597.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="IVZ69_000480"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="IVZ69_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HAP8182598.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="IVZ69_000481"
     CDS             52447..53100
                     /locus_tag="IVZ69_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HAP8182599.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="IVZ69_000482"
     CDS             53326..54324
                     /locus_tag="IVZ69_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HAP8182600.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="IVZ69_000483"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="IVZ69_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HAP8182601.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18553 a         9728 c        11687 g        16415 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaacg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccgc cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcat tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gccaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt att
//
LOCUS       DACDAF010000009        53022 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.009, whole genome shotgun sequence.
ACCESSION   DACDAF010000009 DACDAF010000000
VERSION     DACDAF010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 53022)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53022)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53022
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.009"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            301..621
                     /locus_tag="IVZ69_000484"
     CDS             301..621
                     /locus_tag="IVZ69_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HAP8182602.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            775..1680
                     /locus_tag="IVZ69_000485"
     CDS             775..1680
                     /locus_tag="IVZ69_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8182603.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            1677..2450
                     /locus_tag="IVZ69_000486"
     CDS             1677..2450
                     /locus_tag="IVZ69_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP8182604.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(2631..4055)
                     /locus_tag="IVZ69_000487"
     CDS             complement(2631..4055)
                     /locus_tag="IVZ69_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8182605.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            4266..4712
                     /gene="nrdI"
                     /locus_tag="IVZ69_000488"
     CDS             4266..4712
                     /gene="nrdI"
                     /locus_tag="IVZ69_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAP8182606.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(4777..6759)
                     /locus_tag="IVZ69_000489"
     CDS             complement(4777..6759)
                     /locus_tag="IVZ69_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8182607.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(6773..7669)
                     /gene="murQ"
                     /locus_tag="IVZ69_000490"
     CDS             complement(6773..7669)
                     /gene="murQ"
                     /locus_tag="IVZ69_000490"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP8182608.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(7672..8733)
                     /locus_tag="IVZ69_000491"
     CDS             complement(7672..8733)
                     /locus_tag="IVZ69_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP8182609.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(8944..9471)
                     /locus_tag="IVZ69_000492"
     CDS             complement(8944..9471)
                     /locus_tag="IVZ69_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP8182610.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            complement(9538..11040)
                     /locus_tag="IVZ69_000493"
     CDS             complement(9538..11040)
                     /locus_tag="IVZ69_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP8182611.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(11298..12419)
                     /locus_tag="IVZ69_000494"
     CDS             complement(11298..12419)
                     /locus_tag="IVZ69_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP8182612.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            12545..13486
                     /locus_tag="IVZ69_000495"
     CDS             12545..13486
                     /locus_tag="IVZ69_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP8182613.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(13636..14532)
                     /locus_tag="IVZ69_000496"
     CDS             complement(13636..14532)
                     /locus_tag="IVZ69_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HAP8182614.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFNMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTSFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            14801..16141
                     /locus_tag="IVZ69_000497"
     CDS             14801..16141
                     /locus_tag="IVZ69_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8182615.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            16359..16802
                     /locus_tag="IVZ69_000498"
     CDS             16359..16802
                     /locus_tag="IVZ69_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HAP8182616.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILTSKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(17067..18485)
                     /gene="nhaC"
                     /locus_tag="IVZ69_000499"
     CDS             complement(17067..18485)
                     /gene="nhaC"
                     /locus_tag="IVZ69_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HAP8182617.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPKLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(18888..20111)
                     /locus_tag="IVZ69_000500"
     CDS             complement(18888..20111)
                     /locus_tag="IVZ69_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HAP8182618.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKEGFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVEQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(20142..20981)
                     /locus_tag="IVZ69_000501"
     CDS             complement(20142..20981)
                     /locus_tag="IVZ69_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HAP8182619.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETTVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNAALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDEKNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(20998..21678)
                     /locus_tag="IVZ69_000502"
     CDS             complement(20998..21678)
                     /locus_tag="IVZ69_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182620.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(21680..22753)
                     /locus_tag="IVZ69_000503"
     CDS             complement(21680..22753)
                     /locus_tag="IVZ69_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8182621.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IIEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRQKALDYLIKS
                     GVKINILQKNELDSRIKVIEGGR"
     gene            complement(23399..24070)
                     /locus_tag="IVZ69_000504"
     CDS             complement(23399..24070)
                     /locus_tag="IVZ69_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP8182622.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYFDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLD
                     KKTEK"
     gene            complement(24157..26835)
                     /gene="mgtA"
                     /locus_tag="IVZ69_000505"
     CDS             complement(24157..26835)
                     /gene="mgtA"
                     /locus_tag="IVZ69_000505"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HAP8182623.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLTFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASMFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGKFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQQVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNVTFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIHRFQELL"
     gene            27494..27931
                     /gene="ndk"
                     /locus_tag="IVZ69_000506"
     CDS             27494..27931
                     /gene="ndk"
                     /locus_tag="IVZ69_000506"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HAP8182624.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAVDAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(27953..28819)
                     /locus_tag="IVZ69_000507"
     CDS             complement(27953..28819)
                     /locus_tag="IVZ69_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8182625.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICSKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLSLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEKKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(28979..31072)
                     /locus_tag="IVZ69_000508"
     CDS             complement(28979..31072)
                     /locus_tag="IVZ69_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP8182626.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWMKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVLYWLDIATFIGILVWLTIKKIPIKSQPVSKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFSESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSAIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWNEFDN
                     AQMQRVPLMIHIPGYTKGSVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSPQHD
                     QVVAFRNGNFVTPKYTILGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKSALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNIAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKDNQ"
     gene            complement(31548..32171)
                     /locus_tag="IVZ69_000509"
     CDS             complement(31548..32171)
                     /locus_tag="IVZ69_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182627.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(32330..33727)
                     /locus_tag="IVZ69_000510"
     CDS             complement(32330..33727)
                     /locus_tag="IVZ69_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP8182628.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHPEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(33759..34730)
                     /locus_tag="IVZ69_000511"
     CDS             complement(33759..34730)
                     /locus_tag="IVZ69_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8182629.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKELLEKGVTAIFVSNYNMSIGAIECFNQEGIRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGEQAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            35104..35529
                     /locus_tag="IVZ69_000512"
     CDS             35104..35529
                     /locus_tag="IVZ69_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182630.1"
                     /translation="MKKLIVLFILSAGLLTLTGCNLFGGSDQSSDETTDSSVLKAEKA
                     DITNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQETDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKEATITFTKIGNYRLKDEDGNIYSL"
     gene            complement(36017..36718)
                     /locus_tag="IVZ69_000513"
     CDS             complement(36017..36718)
                     /locus_tag="IVZ69_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP8182631.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIHQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
     gene            complement(36734..37174)
                     /locus_tag="IVZ69_000514"
     CDS             complement(36734..37174)
                     /locus_tag="IVZ69_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP8182632.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            complement(37174..37749)
                     /locus_tag="IVZ69_000515"
     CDS             complement(37174..37749)
                     /locus_tag="IVZ69_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HAP8182633.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            complement(38596..39075)
                     /locus_tag="IVZ69_000516"
                     /pseudo
     CDS             complement(38596..39075)
                     /locus_tag="IVZ69_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015510350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            complement(39234..39935)
                     /locus_tag="IVZ69_000517"
     CDS             complement(39234..39935)
                     /locus_tag="IVZ69_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8182634.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            complement(40043..41452)
                     /locus_tag="IVZ69_000518"
     CDS             complement(40043..41452)
                     /locus_tag="IVZ69_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HAP8182635.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            complement(41500..43365)
                     /locus_tag="IVZ69_000519"
     CDS             complement(41500..43365)
                     /locus_tag="IVZ69_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8182636.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            complement(43486..44337)
                     /locus_tag="IVZ69_000520"
     CDS             complement(43486..44337)
                     /locus_tag="IVZ69_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8182637.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            complement(44647..45360)
                     /locus_tag="IVZ69_000521"
     CDS             complement(44647..45360)
                     /locus_tag="IVZ69_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP8182638.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            complement(45428..45754)
                     /locus_tag="IVZ69_000522"
     CDS             complement(45428..45754)
                     /locus_tag="IVZ69_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP8182639.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            complement(45877..46104)
                     /locus_tag="IVZ69_000523"
     CDS             complement(45877..46104)
                     /locus_tag="IVZ69_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HAP8182640.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            complement(46426..47679)
                     /locus_tag="IVZ69_000524"
     CDS             complement(46426..47679)
                     /locus_tag="IVZ69_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP8182641.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            47740..48480
                     /locus_tag="IVZ69_000525"
     CDS             47740..48480
                     /locus_tag="IVZ69_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8182642.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            complement(48566..49324)
                     /locus_tag="IVZ69_000526"
     CDS             complement(48566..49324)
                     /locus_tag="IVZ69_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP8182643.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(49321..50349)
                     /locus_tag="IVZ69_000527"
                     /pseudo
     CDS             complement(49321..50349)
                     /locus_tag="IVZ69_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
     gene            complement(50369..51556)
                     /locus_tag="IVZ69_000528"
     CDS             complement(50369..51556)
                     /locus_tag="IVZ69_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182644.1"
                     /translation="MKNYNRISANNQLPMIESLRVPTNADKKIYGHVVVPEGVEAKPR
                     DAWTGEVEVTLRITYADTTKSSVEITALTQGQTDENEGAGYNPWGEGEQGGLFEVQVP
                     NDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVDVIPPEPANLSTTLINAASRTIT
                     GTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPENQLFAGDVLEIVLNDQAGEATAK
                     GVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKIVVEGGLSFLAPSKLDFGQIKAT
                     GLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQPFTNDAGFSMQDVLYFKKGEEY
                     QLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLVLTKENQIAGNYSAEITWTLADA
                     PTE"
BASE COUNT        15207 a        11156 c         9136 g        17523 t
ORIGIN      
        1 taatatatag aaataaggtc tagttactgt tttttttaaa tgattaataa ataacaactt
       61 ctttctatga aattgcaaag cattcatctt cttttccgct aacgatatat ccgtcagtgc
      121 ttggtacact ttactaaaaa gtatgagatt gccgatatct ggataggtgt gctatactac
      181 agaaaaagat atacaatctg ccaccgggta ggataaagag gatgatcatt ccattaggtc
      241 tttgaaggga tgattttcct ctttttgtgt atttttttat agttaaggag gaatgtaagt
      301 atggcatgga tggaattaat catagcagga attttggaag tattctggtc aacgatgatg
      361 aaatggagtg atggtttttc taaaatcaat tattcttttt acacagtgat tggcatgatt
      421 gctagttttt actttttgtc aaaggcaatc aaaagtttgc cgatgagtct ctcttatcct
      481 atctggacag ggattggcgc agttggttcg gtcataattg gtgtggtctt gtttcatgat
      541 aagctgaatc tttccacttg gttctttgtg gggatgctac tcatcagtat cattggcatc
      601 aagattacta gcggccacta gacacttgga ataagtactg atcagaaaaa ataagccttt
      661 ttatttaata ttcaattttt ttatgaaaaa ataagaaata agtccaatga cctagcgact
      721 tctccactca tcaggtgtat gcttgtacta tctatagaaa aggagtgaat atttttgaaa
      781 agtctttcgg tccaagaatt atccaagaac tttggtcaca aacaagccct cagcgatgtc
      841 agttttagct tatcccctgg caaaatcgtt ggattagtag gtcctaatgg cgctggaaaa
      901 acaacgatca tgaaagctat tttaggactg atccattact cagatggaac aatctgtatt
      961 ggtgaaaatg agatttctcc ctctagtcat aaagggttgg aacaagtagg agcattgatc
     1021 gaatacccgg gtatctatcc attcttaaca ggctatgatc atctgaagtt attctctgaa
     1081 accaacgatg tatctgctat cgacactatc gtgaatcagc tcaagatgga aaagtacatt
     1141 cacaaaaaag cgaaatccta ctcgttggga atgaaacaaa aattgggaat tgctcttgcc
     1201 ttactgaacc atccgtctat cgttatttta gatgagccga tgaacggttt ggatccacaa
     1261 gcaacaagag atgtgcgaaa aatcattacc gacttggcta ctcagggcac ctctttcttg
     1321 atctccagtc acttactcag cgagcttgaa aaaatggtcg atgagctgat cctgatcaat
     1381 caaggaaaga tcatcaaaca atgtacaatg gctgaattga accaaacagc gcaagatttc
     1441 atcgttatct ctacaacaaa tgatctagct gctcgaacga tcttgacaga agctggatat
     1501 actttggaag atcctgataa aatcaagctt ttaaaagaaa acgaagaatt attaggaacc
     1561 gtgatccagc tattgtctgc acaaaatatc catgtgacag acgtccagca tctgacgaat
     1621 gatttggaat cttctctatt ggaaattctg gattcagtaa agggggaaga agaaaaatga
     1681 cattgcttgt aaaacaagaa ttatttaaat tgatcaagaa aaagtcaact gctgttttat
     1741 ctgttctatt agttgttttg ctcataggaa cagcacttct agccaaaaaa tacacgacga
     1801 tcattgatcc agttgaaatg actgctcagc tttttagtgc cacatcttgg attgtcttta
     1861 tcatgattgc agctgcaagc acgatcattt cgatggaagc acaatatggt acattgaaaa
     1921 atctccttta tcgaaagtat tctcgaggag aaatattagt aagcaaatgg atcacattag
     1981 ttatttattc tgtttattta taccttttag ctattattgt cactgtgttg atgaaactga
     2041 ttcttttccc ttcgatttcc ttcacggaga aggtttctac tggtcaaaca ctgatccaaa
     2101 gcttgttcac ttatactttg ggtagttata tcggtttatg gctgatttta agtttagtgt
     2161 tgatgattgc ttgctttatc aatagttccg gtgcatccat ctcagcagga atcgtctttt
     2221 attttgcttc gtcaatcata tctggtatcc ttattgcact catccaaaaa tgggagtgga
     2281 tcaaatggaa tccgatcagt atgttgaatc tgcaaaacca aattggaaac gaagagatca
     2341 tgaagcaatt gactcatctt tctactaatc aaatgctatt cggtaattta gcttacatcg
     2401 ttttgttctt agcattagga tatctcgtat ttaagcgaaa aaatgtatga tgactcatca
     2461 aaaaagaggc tgtgaaagag acgttcagcc ttattgccga ttggctgtct cttaaacacc
     2521 gtttattctg aaaaaggagc tgtgacaaca tttgtgtcac agctcctttc ctagtatgtt
     2581 tttgaataaa cgacaggctc acaacctctc tttatacttc ttttatactt ctatacgtga
     2641 agcatcccag tggcaaataa aaccattgca atcactccga ccatcgtcac acctataagt
     2701 aaaatcttat ctaagtggat atgttgtaca ggctcgtttt gctccttacg tgctttgagg
     2761 taaaaataaa tgcctggcaa gaaaagaaca agaacaagca ttacttcatt aaaggctacg
     2821 actagcatag cccatacttg aaaggcactt gctaaaagcc ctactaaaaa ttggacccat
     2881 tctttccgct gataagaaag tttcatttgg tacaatccta agaaaagcca cgtgaagaaa
     2941 atagctgctg taccaagtgt gtaagcaaag ttataagcac tgtcagtgaa taataatgaa
     3001 agtaaaaaga cattcgtaca taacgtcgtc aatacgatag cataagttgg tgccccattt
     3061 ttgttgagtt ttccccatgc tttaggcaaa agtccgtctt cagccatgtt tcccattgtt
     3121 tcaatcggta agatcgtcca tgagagccaa acaccaacta aagaaatgat caaaccgccg
     3181 ttgatcacga ctgctcccca tttaccaacc atcatttcaa acacatagcc catagcaggc
     3241 tgcgccttga tcgtttgcag ctgattcatc gtcattgtcc catatggaag catggaaacc
     3301 aagacgtaaa taataatcaa gccgaatatc cctagaatcg ttgctttccc aacatctgat
     3361 tgtttttttg ctcgtgaacc tacgacagag gctccttcaa taccaacaaa tacccaaagc
     3421 atcaccatga tgcaactcaa tacttgactg gaaaacggga tcggctgtcc attcgcattc
     3481 aatataatgt cgctagaaaa gttatcaatg aattgttgga tcgaaaacgt gctgatagct
     3541 actacaataa ataaaaataa tggcactaat ttacagaatg tgacgatagc attgacgaaa
     3601 ctagcatttt cgactccccg attcactagc catgcatatc cccataaaaa gactgtactc
     3661 atcacgatcg atgccagatt ttgcccacct tcaaatactg ggaagaaata tcctaatgcg
     3721 ctcatcaaca atgttgcaaa agctacgttg cctaaccagc atgtgagcca gtaaccccaa
     3781 ccgctgataa aaccagcgaa acggccaaaa ccttcttctg cgtaactaaa gatcccgcct
     3841 tttaaatctg gacgtttttt attgatatta ttgatcgaca aggagagcat caacattgct
     3901 gttcctacga gtacccaact gaaaatagct gggccgccag ccgatccgga gatgtccgtc
     3961 ataataccaa atacgccacc tccaatcgct gaaccaatta ctaaggcagc aagtggaatt
     4021 aaaccaattc cttttttctg ttgctctgta tccatgtaag catcctccaa aataaaaccg
     4081 cttttatcaa aaagtataac aaaccttttt tatttttact taattaataa aaactttaat
     4141 agaaatataa ttctaccggc ttttttctca ttatacaagc aaagcgccta gtccctttcc
     4201 aaattacacc accaaaaaac ttaaaaaaga tgctatacta aaaggaaaga attggaggat
     4261 gatccatgaa cattttatat atatcgattt caggaaatac gcgtgccttt gccaaacatc
     4321 tagcagaata tgctgaaaaa atgcatgcag aagatcctgt caatcctgaa gttactttaa
     4381 aagaaatcca tgaaaatagt gattttacga aagaaacaga accatttttt actttcgttc
     4441 ctacttattt agacggcgga aatggtttag ataacggtga tacagaaatc ttgaccgaaa
     4501 cgatgcgtga atatctggaa catgaagaca atcataaact ttgtcttggt gtagtcggta
     4561 gcggaaataa aaacttcaat aatcagtatt gtctaacagc caaacaatat gcacaaacat
     4621 ttggctttcc tttcttggca gattatgaat tacggggaac accatctgat gtgacacgaa
     4681 tttatcagat tttagcagaa aacaataaat aataaaaaag aagaagctga aaaatagatt
     4741 tcagtttctt ctttcgtttc tattgtttct atcatattaa gctttgacat ccatcacagg
     4801 tgcttttgct tttgctttac ctgttttttc caagacaaag ttttttacac gatccatatt
     4861 ggttaccaag acgatcatgg atgtttcttt gcctgctgct ttgatcgctt ctaagtcagc
     4921 ttctgctaca agcgtatcag gtgtcacttg ctgcccttct gttactttca catcaaatgg
     4981 cgtaccgcct aagtcaactg tgttgattcc catatgaagc aagatttcta aaccatttgg
     5041 cgttgtgatc ccaatagcgt gtttcgttgg gaagacagag ctgactaccc cagtaactgg
     5101 agaatagata tgtccgtttt ctggttctac aaagtagcct tcacccatca tcttttgtgc
     5161 aaaaactgga tcacttgctt tatctaaaga aacaactgtt ccgtcagcaa ctgatgagag
     5221 gatagtcaca ctttcagctg aagtttgagg tactactttt tcaggcactt catttactgt
     5281 ggctgtttca gtcgctaatt cttctttttc taaacggtct ttaggaatac cgaagaagaa
     5341 tgtagcaacg aagccaccag cataagctgc caataatcca aggatgtagc ctaaccattt
     5401 accgtcagag atcaatggga tcaaagcggc tcctgaaggt ccaatagcga tagccccgac
     5461 atttccgatc attccgatca ctgccccgcc gatacctcca ccgatacaag cagtaataaa
     5521 tgggcgtcct agaggtaatg ttactccgta aatcaatggt tcgccgattc ctaggatccc
     5581 gactggtaaa gctcctttga tcatttctgt taattcttta tcttttttgc agcgaatcca
     5641 taatgccaat gctgcaccca cttgtcctgc accagccatc gcaagaattg gaagcaatag
     5701 cgtacgacca gtttcatcaa tcatttgcac atggattgga gtcaaaattt gatgcagtcc
     5761 gaacataacc atcggcaaga ataatgtgcc tagaacgaag ccggcaaatg ctccaccaac
     5821 gccaagtacc cagttgatcc caccgaccat gccatcagaa atgaaacctg ctaaaggcat
     5881 gatgaagaaa atttcaatca gaccgatggc aatcaatgaa agagttggtg taacgatgat
     5941 atctaccgca tcaggtacta ctttatgcag ttttttctca acgattgaca atagccaaac
     6001 agcgaagatg acacctagga tcccaccttg tccagctgca agagcttcac cagtaaataa
     6061 gtttttcagt ggtgcttccg gattcatccc tgtcagcatc acaacggccc cgataactcc
     6121 accaagagtt ggtgttgcac caaaaacttg tgcagcattg atacctgtat agataactag
     6181 gtagctaaac atcccgtttt tcaagatgtt catcacatcg atatattgtt gccatgttgc
     6241 tgcatcaagt gttccggctg tgactaagtt tgctaaaact gcggcaatcc ctgccacgat
     6301 cccagtaccg acaaatgcag gaatcattgg cacaaagata ttagaaatgt cttttaatac
     6361 cgatttgatt ttagatggtt tttgtttcga tttttgtgcc gctttcattt cttgtgcccg
     6421 ttcgtttaca cggtcttttc cagatgctga tgaatttgct gtagctgtac ttacagaaga
     6481 aagtttttct cctaatttca cgcctgccaa atcaaccatt tgctgtgcta ctttgttcac
     6541 tttcccaggt ccgatgatga cttgaagctg ttcatcttct actacaccaa gcactcctgg
     6601 aatcgctttt aattcagaga catttacaag atcatcattg atgatcttca tacgcacacg
     6661 agtcatgcag tggacaatgc tttctacatt gcccatgccg cctgcccctt tataaatttg
     6721 ttttgccagt tcttccaaag tcagttcgtt ttttgccatg gtcttttccc cctcataagg
     6781 tcccttttac aaatccgttt gcttcagcta attttgcttg agcttcctct ttatcactat
     6841 ttgtcaaaat catgacgata gccagcttaa cattttgatc tgcttcttca aagtactttt
     6901 cagctgtttc gtaatcagct tctgtcgctt gcatgatgat tcgttttgag cgttcgatta
     6961 gtttttcgtt tgttggtttg acatcgacca tcaagttatt gaatacttta cctataccaa
     7021 tcatactgat agtagaaatc atattcaaga taagtttttg tgctgttcct gacttcaatc
     7081 gagtagagcc tgtcaaaaat tctggacctg catcgacttc gattgggaaa tccgcgtgtt
     7141 tactgatttc ggcttgttta ttgcaagaaa tcgttcctgt gacagcaccg atcgattttg
     7201 cgtaatctaa tccaccgatc acatatggtg tacgaccgct agctgcgata ccaataacta
     7261 tatcattttt tgtcaaattc agcttgatta gatcttcttg ccctagctca taagaatctt
     7321 cggccccttc gacagctaca gtcattgctt cttctccacc agcaattaga cctatgacca
     7381 tttccggttc tacaccgaat gtcggtacgc attcagcagc atctaacaca cctagtcttc
     7441 cacttgttcc ggctcccata taaatcagac gtccaccttt tttaaaggac tcaatcgtgt
     7501 tagcaatcac tggttcgata cttgtcagtt ctttttcaac cgcagcggcc actttctgat
     7561 cttctttgtt cattagttga acggcttgag aaatactcat ctcatctaat ccaaaagttt
     7621 cttggtttct gcgttccgtt gttaggttct ctaaattgat tttgctcatt tttatcttcc
     7681 ttcttttctt ataaattgat agttcatacc agctttgatt tggttgatca atggtagctc
     7741 ttctttgata actttagcta ctacattcac tttttcatcc gctggcaaat catatttggt
     7801 taattggatc tcacccatat agcgcaaata cttttcgtta tctaaagtaa tagacccttt
     7861 catacgcgta gctgtatttc ttgctgggat aggcggaatc tctcgaaaac gtgcatctac
     7921 gcttcgtatg acatctcttg catcgtcttg ccgattcgta tgcttcccta atatatattc
     7981 gtaaaattct tcatctacag gttccgtatg gagcaagact gtctgttctt tttggaaaga
     8041 agcaaattgc tcctgaacgt tttctgacag acctgcatct ccgatgtaaa caatatccgt
     8101 gttacttgct aatagatcta gagcgcctgc aagaggatgg atccctcgat gttcttccaa
     8161 agttggcaat ccttgatata gtgggcctct caactctgta tctcctggta caaaaccttg
     8221 gacaaggaga ccttgaattt tgagccattg attttttttc tgataccatt ctttgtccag
     8281 ccctgtttcg ggacgtggat aataattatg ccaagcttca atctgtgaga aatcagcttc
     8341 tgcttctttc aattcatcga tatctttagg cgtgatcgtg ctagcattca aactgatttt
     8401 caattgatgt gaccagtcgg caatctgctg attggaaata tgataatcca ttcttaaacc
     8461 tgttacacca attgctttca aaggcgttag atcttctaat gaaaaacccg ctcgttccaa
     8521 tgcctctcct gaaatatcga ccatcaattc tagtttattc tttttcgctt cgcttcctag
     8581 ttcgatcaat cgcttttgat atgccgaaac atcatcttct ggtatatgca tggaagtgaa
     8641 aataccgaca aagccattgg atgccatttg gcggatatac tgtttcttct cttctgacaa
     8701 agaatcgttc ataaatattg aaaagccaaa catattatcc ctctttttct gtatccgtct
     8761 tcatttctat gactagagta tatatctaaa gaaacaaaat ttcaatactt ttattaaaac
     8821 aattaaattt catttctaaa ggttgagttt atattatcaa aagaattgtc ataacctaaa
     8881 aaaggcactg ctaagcaaaa gcagtgcctt gaaatatttt atttaaataa cacaaaaaca
     8941 taattactca taagaaacca attctgtatt atctaccatg aatgtaaaga acccctcatt
     9001 aggcatcgga tgaaaataag cattgatcac tcttatcaag gcattatggc aaactaacag
     9061 atagacattt tcttcgtctt cgatgcattc tttcaataaa ggaacgatcc gtgcatacac
     9121 atctaagact gactccccat ttgggaatcg tacagcgaac gctaaacgtg ctttttgaaa
     9181 gttctcatct ttgcttggca gtccatcata atccccaaaa tccatttcta ccaatcgttc
     9241 atcaacggtc agcggcaagc tgagacgatc agcaactgct tgtgctgtat ctcttgctcg
     9301 ttgaagaggg gaatggatga ttttcgtgat tggaacaggc aaatctacta ccttttctgc
     9361 tagtttctgt gcctgcatct gtcctttttc agtcagcggc acatctgccc gtccgcaaac
     9421 taatccttgt gcgttccaag ttgtttctcc gtgtctcgtt acataaagca tgtgattctc
     9481 tccttcgttg gcaaagttcc ccttaaccat accttgttgt tcttgagatt acaagggtta
     9541 gattctctca agagaaataa tctcagtaga tactttatcc aggaaggttt gatcatgttc
     9601 cactagtaac atggcaggtt tcacgttcaa gatcagttgt tctaattgtt cttgattgaa
     9661 gacatccaaa taattcaatg gttcatccca tgtatatagt tcagctggct gtgataaaga
     9721 tttagccaat tccacttttt tccgttggcc catactcatc tgctcgatct tgttatgaaa
     9781 aacatctctt tccatcccaa gctttcggag gttgttcaaa aatgcttggt agtctacttg
     9841 gtttttctct gcaaattccg ccaacgttcc tcgattgtct tcataatttt ggcttgcata
     9901 actaatgctc agatgttttg gctggtattt ttctcctata accttgccgt tgaatgcccc
     9961 cagaagataa tggataatgg atgactttcc tgcaccgtta ggacctgaaa tcgccacccg
    10021 ctgatgaggc tcgattgtaa aatgaattgg ctcgaataac agattttcat accctaattg
    10081 aagatcttct acgcttaaaa gtcgcttatg gtgagacgct tggctattca tcgtcaaaga
    10141 atcgatatat tcgatatctt ttaatagttt ttctttctcg ctgatctggg tctccatccg
    10201 attcacgatt gctttggatc gtttcatcgt ccgtgcagca tcagcaccca ctgctccttt
    10261 attcactcgt ctagattcag tatcgatgaa tccgacttgt ttctttgttt tatctccttc
    10321 tcgggaacga gaccattcgg ctttttcagc tgctgttttc tttagcctac tgacttcttt
    10381 tttcaatttt tcattttgag ccatttcaaa ttcatcacga agttttttct gttcttcata
    10441 gatagagaaa ttcccttgat aaagttccag ttgacttttt tcgattgcta aaacatggtc
    10501 cactacttca tcgataaatc cccggtcatg gctgaccacg atgaagcctt gttttttctt
    10561 tttcaaataa gccgctactt gttttctacc agagatatcc aaatgattcg ttggttcatc
    10621 gattaacggg aaatgagtgt catccacaaa taaaagtgcc agtaggactt ttgtcttctc
    10681 tccccccgat agtgtgctga attctctcca taagatttca ggatctgttt gcatcaattg
    10741 gagctctctt tcgatttccc atatctcaaa atccgtaata tcatttaaca cgtaataggt
    10801 taaacgttct ttatcttttg tctgttgcgg gaaataggca aattcttgct gatggattac
    10861 ttgcccttga taaggtagtt tgttttgtag aatattcagt aaagttgtct ttcctcgacc
    10921 gtttcgtccg ataagtccta gtttccattg tgtgtcaaaa tttagatttg cttgttcaaa
    10981 taataatgtg ccttggctgt cgtagccgaa tgtcagattt tttatttcga ttttagacat
    11041 tttccatcac ctcgtaaaaa aagaccagtc ctattttcag aactggctaa agaggataca
    11101 agggttggat acacacaaaa agacccatac atcgaaaaaa ccaagccaat cccgaaaatc
    11161 tgcacactgc ttccttgtct ccacaaggta cagtctgaat gcagctttca tcaatcgact
    11221 taatttttca atgcacggat ccctcacttt gtcctatatt tgaaattacg atagcataaa
    11281 gaaaatgatt ttgtcaacta cttcgggagg atggtgaaaa atctgctaag tgtctgtcct
    11341 aagatttttg ttttttctaa tgtttgcctg tgttccattg cttcttctaa acctattgga
    11401 cccaaatgaa tacttaagac aattgggaga aaatcagaaa gtccttctag ctcttggtct
    11461 ctacttccgc aaatagcgat tattggtttt cgatattttt ttgcaagcac tgctacaccg
    11521 tatggaactt ttccgtggat cgtttgctga tcgatccgcc cttctcctgt aatgatgaca
    11581 tctgcttgtt cgatcttttt ttccaatcca gtgatttggc tgactaaatc gaaaccagaa
    11641 accatcttcg ctcccaacaa aaaaagggct ccaccaatac cgcctgctgc tccacttcct
    11701 ggaatatcat ctaaatccac ctcccagaaa tcttttattt gctgagcaat ctttcctgct
    11761 tgtttatcta agaaagctag cgtcgtatct attcctcctt tttgtcttcc aaattgccaa
    11821 gcagctcctt gttgacctgt atatggattg gtaacatctg cagcgataat caattttact
    11881 ttagaaacaa gaacgtttct tcgatcaaaa tgaagttttt tagtagataa taaaggattt
    11941 ccttctgtgt acccttctaa agaagcaccc aaggattgga gtaatcctag accaccatcg
    12001 ctacacccgc ttcctcctaa agtgacaata atttgttcta cttcttgaag cagtgcatct
    12061 ttaataagtt ctcctaaggc ataactggaa gcaagtcgga tagtttgatc cgttggttta
    12121 tcaagtagat ctaaccccaa tgcttgtgca gattcgatga ctgcggtgtt ttttccttgc
    12181 caagttgtca ataaatagct gatttttcgc tgacggaata agagatccat cccatcaatg
    12241 gtacgccatg ttcccctgag cgcgtaatag attgcttctg cagtattttc tccgccatct
    12301 gcaatcggca cattgatttt tcttccttta cgatcttccc agccatttag aactgcctga
    12361 tttagttcaa atgaagaagc acttccttta aatgaatcaa ttgccgccaa aatatccatc
    12421 tgtatccctc actttcttct taagtaagac actttttttc atttttttca aacaaaacaa
    12481 tgctattttc ttccattttt ctatatacta aaagggaact cattgaataa aggagagaaa
    12541 aaacatgaaa atcgcaatag ctggggccgg agcaatgggc agccgaatcg gattgatgct
    12601 acatcaaagc ggaaatgagg tcctcttgat cgatcgttgg cctgctcaca ttgaagccat
    12661 tcgtacaaat gggttgattg ctgactttaa cggtaaagaa gtggtcgcaa aactgccaat
    12721 ctattcacca gaagaaatca tcgaaagcaa cgaacacgtg gacttgatcg tagcattaac
    12781 aaaagccaat caattagatg atatgttttg ttcgatccaa tccattatta ctgacaatac
    12841 ttatgttttg tgtttactaa atggattagg tcatgaagat gtactggaaa aatatgtgcc
    12901 aaagaaaaat atcttatttg ggatcacgat gtggacagct ggtctagctg gtcccggaaa
    12961 agtcacattg ttaggtgatg gagaaatcga actagagaac ttggaaccag aaggcgaagc
    13021 atttacaaaa aaagttgtag aagtctttca agaagcaaat ttaaatccga tctatagcca
    13081 taacgttcgt tattccattt ggcgaaaagc ttgtgtaaat ggaacattga atggtttatg
    13141 cacgattttg gattgtaata ttgctgaact aggcgcgcaa aaagcggcag agagcatggt
    13201 tcgaacaatc gtatctgaat ttgcttctat cgcagcaaaa gaaggaatca tactagatca
    13261 agaagaagtg taccaacata ttgcttctac ttatgatcct gacaacatcg ggttgcatta
    13321 cccatctatg taccaagacc tgatcaaaaa ccatcgtttg actgaaatcg actacatcaa
    13381 tggtgccatt tggcgaaaag gacaaaaata tgatattgct acaccatatt gtgccttttt
    13441 gacccaatta gtccatgcaa aagaaggaat ccttggcgca gaataaaagg ctctctgatg
    13501 agaatcagct gaatcagcag ctggttctct ttttttaagc ccaataaaag atcaaaaaga
    13561 aaacacaact ctcatgatgc cataagaatt gtgcttgttt gtttcagtac ataatctctt
    13621 caaaatgtag gttttttatt tgttttcaac agaggagagg tcatattcgt attgctcata
    13681 aatagtggaa tcgttagtga taaatcgttt tgcccaattt tctgcatcat aaaattccaa
    13741 tagctctgat aggattggct taaatgatgt atgcagaaat tccggtaatt catctaaatc
    13801 acgttctcga agcaaaaaaa tattttcagg acgataaaaa tgataatgag caatcgcttg
    13861 attatccgtc actagtttct tttgaaaata catggattca aatgtccgca aagtcactcc
    13921 ttgctgaccc tcccgcaaca gttccagaat cccgcgcgat tcccctgttt ttttcaggta
    13981 ctcttcataa gtaagatatc caggttgttc attccctcga tgtggaagaa tgaaatagtt
    14041 ggtcgtaaca tctcttttta taaattcctg cttatagctt tctgctcgtt cttttctccc
    14101 attattcgtt gcaccaaaaa atagatccgt ctttggttcg ctagaagaaa aattcatatg
    14161 tttcgaataa aatgaactat tatgtttcag cccaagttct tttgcttcca aaaaatcaaa
    14221 atgataaatc tcatcgattg ccggttcatc ttgtgcctgc ttcagcatcg cctcgtgttc
    14281 tgctttgaag tgattccaaa aaaataacac aatttttgca ttggtaaatg ggcgcacgcg
    14341 tcgagccatc tccatattaa atccataatc taaaaaaacg atcagctgat aatttgccaa
    14401 ctgttgtcta gctgatttaa tgaattccga ctgtagtaaa tcttttccgg accaaacatc
    14461 taaagagcgg atggaaggca aaaaataaag tgatttattt tttgcaacta gcagtacgtc
    14521 atttttgttc atcttttccg cctcactttc tctgtcactt tttcctatga tagcctgttt
    14581 aaatagtaaa aagccagtaa aacgcttcct atatttgtat gaaaatttaa catttgtatg
    14641 aaaatatgat gaaataaatc attcttctat taaaattcgc ctaaaagttt tctgaatagt
    14701 tgtaattgtc tgaaaatttg ttatcattag tcattgttaa atattgctat ttattcttaa
    14761 tataaatttt gattgtgaat ttaaaagaaa gaggtcattt atggaagata aaaaattgaa
    14821 aaaacaactt agctccagac atatcaccat gttagcttta ggtggagcaa tcggtgcagg
    14881 tctatttaaa ggaagtggcg aagcgattgg gatcgccggc ccttctgtat tgattgcttt
    14941 tttgattggc gggctgattt tatatatcgt gatgaaaggt ctgggaaaaa tcgttttaag
    15001 cggtggcgac acgcatcacg gattatctgg tttgatacgc ccttatctag gtgctcattc
    15061 tgctgatttt actgattggg tctactggtc tatgtggatt atcaatatca tcgctgaagc
    15121 tgttgcagct gcttcctttt tgcagttgtg gttcccgcac attccagcct gggtatttgt
    15181 ttttatgttg gctgttttaa ctacgatcat caatctttat tcggtacggt tattcgcaga
    15241 aacagaatat tggctggctt ttgctaaaat cagtgtcatt atcttactaa tcatttttgc
    15301 tacttatctt gtcggtcagc aaatgttggg cacaggcgtt ttccctaccc ttcagcaatt
    15361 gactgaccat ggtgggttta ctcctcatgg tatgaaggga atcatcagtt ctttgcttgt
    15421 agttatctat tcttacggcg gttctgaact gattgctatc acggtaagcg aagcagatga
    15481 tcctaaacgt gcgattccta aagccatcaa aggtgtcatg ggaagaatca tttcctttta
    15541 catcattcct ttgtttttgc ttttgattct ttttccttgg aatactttag caggcacgaa
    15601 tgtcagtcct tttgtgatgg tatttgaaaa aatgaatatc ccatttgcag cggatatcgt
    15661 caattttgtt attgtccttg ctttgttctc atctatcaat tcgggtgtgt atgcatcttc
    15721 aagaattttg ttcttccgtt tgaaggatcg aaaaggttcc tctagaaaac tagctgtttt
    15781 aaacaagcat caagtaccgc aacgtgctgt tttattttgt accagtgttc tttatcttgg
    15841 tgtagctctt tcttattttg tcggtgacaa attatttggc tatctggcag gttccctttc
    15901 gtatacagta ttattgatct ggatcattat cagtgcggca tcctttgtac tggcactaag
    15961 aaaaggaaca ttatgggata aaggaatcag cttttttgca ttagctgtct taggattgat
    16021 tttccttggt atcctgttca cgaactccat tggggtaact gtattgactg gcctgcttta
    16081 cctgttcatt tatttcagtt atcaaaaaaa gaatgatgcg ttcgtattga cgaatgaatg
    16141 aaatcgatag aaaattttat tttatttatg tggaatagat ggaactattg aagaaaggag
    16201 ttgtgacaaa agtcttgttg caactccttt ttccgaataa acagtctcat gacctcttgg
    16261 taaacggtgt tcaaaaaccc tctgtgcaaa ataattgatt gttctccatg ctcatgacat
    16321 gatagaagaa aggaatgaaa aaaaggagtt tgttttaaat gaaaaagtat tggaagtttt
    16381 tgttgatgat cggtgtttca acggtagtta tgtttggtat gatgtacttg aatgtctatg
    16441 cgctcgatca tatcttcttc agtcgtacac gagtattcat ggcgttgatg atgggtgcag
    16501 tcatggcagt catcatgctg ttgttcatgt ggaaaatgta tgaaaacaaa aagataaatg
    16561 ttatgatctt agccgctagt cttcttgttt ttgccggttc cttgtttatg gtacgaagcc
    16621 aaactactgt caacgacaca gcttggatga aggccatgat tcctcatcat tctatcgcta
    16681 tcctgacaag taaacgagct gatttaaaag atcctgaagt aaaaaaatta gcggaagaaa
    16741 tcatccaggc acaagaagaa gagatcgaca aaatgaaaaa aatgatcaaa gaaatggaat
    16801 gaccattatc cgtccaaata aaaaaagagg atgttccaga agtgatcagc ttcaagaaat
    16861 aagaagaagc tacttctgga acaccgtgaa taaggggttg tgaaaaagct gccctgcatc
    16921 aagtaataag aacagccaaa caaaaatagc ttctcctatt tttcgtttgg ttaggcttat
    16981 taccgcagat gcaagctttt gaacaccgtt tattcgtaaa agggattgtg acaaaaaaag
    17041 tcttgtcaca atcccttttt atgtttttat tgttctaatt gcgctgtctt gcttactgct
    17101 tcttgcggtt tcacaaattt ttttgagatt ccccaacctg tgaaggcact gaccatcgaa
    17161 aacacaggag aaagcaaact gaaaaatacg aatggcaagt aagtgagtgt aggaatacca
    17221 aatgtacttg ctacgaaact tccggcaatt ccccaaggca ctaagtagtt gattactgtt
    17281 ccaccatctt ctagcgttct acctaataca gttggatcaa atcctgcttt ttcataagtt
    17341 tctttaaatg cattaccagg cagaataaca gataggaatt gttcaccaat aaaaatattt
    17401 actccgatac ttgtcatcaa tgttgtaaaa atcaattttg gtgtgttcgt catctttctt
    17461 gatactcgtt ccatcacggt tgagatcaag ccaaattcga tcaacaatcc acctaatgac
    17521 aaagttagaa taatcaatga cacagtaggc atcatacttt cgattcctcc gcgactaagc
    17581 agtgaatcga tttgttggtt tccagtattt gaaacaaacc ctgattcgat gaccccagcc
    17641 aacttcgtta aggaagtttg tgggttttga ataaaaatca ttcctactgc tacagcgata
    17701 ttcaacaaaa tcgtcaaaat tgccggcacc tttttccatg cacacagtaa cattaaaaat
    17761 aaaggaatca gtgaccagat tgaaatagta aagtttgctt ctagaacatc agtcacttca
    17821 cgaatagatg aaagacttgc ggctttactt gtgtgcccta aaatcatgaa taaaaagaaa
    17881 gaaacaacaa atgccggaac agttgaccac atcatatgct tgatgtgttt gaacaaatcg
    17941 gcatcaacaa tagctgctgc tagatttgtt gattcggata atggagacat cttatctcca
    18001 aaaacggcac ctgaaacaat agctccaaca accagcgctg gatttaggcc tagtgttgtc
    18061 ccaataccga aaaatgcaat cccaatcgtt gacataacag taaaggcact ccctacagcg
    18121 ctacctacga ttgcacacac aacaaataca gaagggacaa accactggac actgatcaat
    18181 ttgaacccaa tgaccattag agttggaatg atccctgctt gtatccatac agcaatcaat
    18241 gaacctacta aaataaaaat aaagattggg atgattcctg gtttgatgcc attgatgatt
    18301 ccttcgtgca gccaatctgt cgggtatctt tttatcactg catacaacat gaccattccg
    18361 atcgctgcta agatcgtgat attaggtgag acctttaatc cgacaacgcc aatcgcaatg
    18421 cctaaaacaa taaccattaa tacaagtgtt gcttctaaaa aacttggtgt tccttttttt
    18481 cccatgataa tctctccttt tttagttgtt cttatgttct aaaaaagtta agatatcgga
    18541 ttactccgcc gcaattcatc cgctattcct cctttataaa aataaaaaga cctgttttaa
    18601 actaaggacg aatgactccg cggtaccacc ttaattaaaa acagatctgt ttttcacttt
    18661 caaactttta ttcaaatgta tggactttcc atgtaattcg tcaattaggc ttgatcggtt
    18721 cacagcgacc accgactttc tgaacaaaac acctaaccgc tactgcgtga aaagttgact
    18781 tgtatgaagt ttaccttcca taagatcatt tgtcaatgaa aaagaaaata ttttttcatt
    18841 tttctgaaaa ttatttttat aactttcaca cacaagttta ttttttacta gaaagtagca
    18901 ccctcttgtt tttttcttgc tactatttct tgatgttctt gcttgattct ttctaatagc
    18961 tttggctctt tcaacagatc aagagctgta ttggcgagta gttctgctgc aatcgcaata
    19021 gaagcaaggc ctttgtcact tttagcagca gctttgaatt cttctgtgtg tccggcaata
    19081 tatgtctcag agattgctac cgtaggctgg attgttggta tgacttggct gacatttcct
    19141 acatcagaag aaccgagact tgttctttgt tccgtttcta tttcttcatc tggaacacct
    19201 gcttcttttg catgctggaa gaataagtca tcaaaagaag gagtaacgat gacatcatca
    19261 actgcatttt ggaacaatcc aaactcaaaa gtcgtgcccg tacttatcgc agcacctcgt
    19321 acgatatttt ccactttttc atatacttta tctaatgttt gccgatttcc tgcacgtaaa
    19381 tagaaacgtc cagcagcgta atctggaatg acgttggcag ctactcctcc gtctgtaatg
    19441 atcccatgga tattgacatc ttttggcaat tgcaagcgta gagcgttgat tccattaaac
    19501 acttggatca atgcttccaa agcatttact cctttttcag gtgctgctgc tgcatgggaa
    19561 gcgacaccgt aaaatttgat gtcgactgga tcattcgcta aagattctgt cgttttccca
    19621 taacgaaaag ctggatggac gcataacgct acatcgacat cctcaaaaaa accttctcga
    19681 acaaagctgc ctttagctga tccgttctcg cccccttctt cccctggggt gccatataca
    19741 cggatttctc caccagtttc atcaataaat tgctccacta tgctggcggc taatacggag
    19801 taagtaccaa acaaattatg cccgcatgca tgaccaatac ctggtaaagc atcgaattct
    19861 gccaaaaagg caattgtggg tccgggttta ttggaaatat aacgtgcatc aaaggctgtt
    19921 cggtgtccag ctacttcttt ttctacccaa aacccttctt tttctaattg tttaatcaac
    19981 gctgctgagg aataaaactc atagttactt acttcaggat gttcgtggat atctagagca
    20041 agtgcttgat attctggtaa acgatattgg attagatcct tcaattggtt tgttgagatt
    20101 gttgttgtca taaaaaattc ctcctatgct agtcattttt cttattttct cccgaatgtt
    20161 tcccatgcag gcacgcttga tccttttgat gttttctcga ttactttgac tgtgtcttct
    20221 gtttgataag cgtctactat tttttgatac gttttatttt tttcatcttc ttttcttgca
    20281 acgatgatat tcacataagg acgtgcatgg tcatccactg gttctaagaa gatggcatca
    20341 gaagcaggat taaatccagc atctacagct acaccgctat tgatcactga aatgtctaca
    20401 tctgacaaag cacgtgctgt ttgggaagca tctaattcag aaatgtctag attttttcta
    20461 ttctcggtaa tatcagaaac agtgggcgct tgtccttttg ccttatccac tttgatcaat
    20521 ccagcagttt gcaataacag aagagctctg ccgccatttg taacatcatt agggattgct
    20581 acttttgctc cgtctttgat atcagctaca tccttcaaag tgttagaata aattcccagc
    20641 ggtgcattga cagtatttcc gatcgatact aaatcagttc cgtgttcttt attgtaattg
    20701 tctaaaaaga attgatgttg gaaagaattc aaatcaatcg atccatctgc taaagccgca
    20761 tttggttgat tgtaatctgt aaatttcacg tattccaaat taatgttctc ctttttcaaa
    20821 cggtctttca cgttgtccca tacatctgta tcttctccaa taattcctag ttttacggta
    20881 gtttcttttt tgtcagttgt atctgctttt ccttggctac accctgccaa ccaaataatt
    20941 gctacaaatg taatgactac aaaacgaata atttttttca ttttttctcc tccactttca
    21001 atgtgtaatt tttttaatca gttgattact gataaattga cttaaaaaaa ctaagattag
    21061 aatcaataat gtagccacaa tcgttacatc tgtttggaat cgattatacc ctctcgatat
    21121 agcaagattc cctaatccgc ctgcacctac tgctccagcc atggtagtca gtccgatcac
    21181 gttgatgata gtcaacgccg agacccgaat gataccaggc aaaccttcta acaaatacac
    21241 acgtaaaata ataccgattg gactggttcc catcgcttct gccgcttcga tcaccccagg
    21301 atcaacttct agcagtgcgt tctcgatttg acgagcaaaa aacggaacaa ctccaaaaat
    21361 caatggcact aaagctgctt tcgcaccaat cgtcgttcca actaagaaac gagtagtcaa
    21421 tgctaaaaga gaaagcaaga taatgaaagg gatggaacga atgatattga tcagcttatc
    21481 aagtatttca aatagcagac ggttagctag taatccatta gggcgtgtca ctactaacgt
    21541 cacacctaag atgattccga tcatcccgcc aatgaatgct gtccaaaaag acatatatag
    21601 tgtttgcttc gtcgcttcga caaattcatc cggaatcaaa taaacattgg gcaaatatgt
    21661 tttaaagaaa tcagtcattt tatcttcctc cttcgatcac tttgatacga ctatctaatt
    21721 cgtttttttg taaaatattt atttttacac cagatttgat caaataatcc aatgcttttt
    21781 gccgctgttt ggtttctcca gctaaagtaa cgatcaaact ccctaacggc gtttcttgta
    21841 ataactctac attgccatat aaaatattcg ctgttacttg atatttgctg tacagatgag
    21901 cgattagagg ttcgttcgtc tgatttccaa tataacttaa ttccaccagc catttattgg
    21961 cgatctgatc ggcaaaagca gaatgggcaa tgatcgtttc taatgcttgg tcaagatgag
    22021 tagctgttcg aataaaatct ttggtcaatt cttcttcagg attgctgaag atctggatgc
    22081 tactaccttt ttcaatgatt cttccatctt ccataaccgc taccttgttg cagatttctt
    22141 tgacaacttg catctcatga gtgatcagga cgattgttaa acctaactgg cgattcaatt
    22201 tttttaacaa tgcaaggatc tgaagggtcg ttttcggatc aagtgcactg gttgcttcat
    22261 cacataataa taccttaggt tcattcgcca aagctcgtgc gattgctact cgttgttttt
    22321 gtccccccga cagttgttta ggataagcag atgctttttc ttccaaaccg acaagttcca
    22381 gtagttcatt cactttttga cgacgttcct gtttcgattt tccagaatac tttaaagaaa
    22441 aatcaacgtt gtcaaaaata gttcggcttt ccattagatt gaaatgctga aagatcatac
    22501 cgatggcctt tctttctttt cgcaattctt tgggagagag ctgactcaaa ttcgtctgat
    22561 tgacaatgac ttctcctgct gttggtttct gcagcaaatt catcacacga actaacgtac
    22621 ttttccctgc acctgagtaa ccgacgattc cataaacatc gcctttttca atcgttaaat
    22681 ctacagaatc tactgcctgt atctcttttt ctttttgttt gaaacataca gaaacatctc
    22741 gcaattcaat cattaaaatt cctccttatc taaaaaaagc gtcctcaaga aaatgaaaat
    22801 gtcattttct tgaggacgct tttttgcgtg ttaccacctc atgttcaagc tgtgttcaca
    22861 cacaactcct cttcaagtac gatcatactc tagcaagata tcggtcgcag ccgtcatcgc
    22921 cttacatcta tgctcgggat gaattgctcg atggccattt tccaatagtc gttccttgct
    22981 tcttctcagc taccgaagct ctctgtcaaa ggttcttcta tcgtacttac catttcaatg
    23041 caaataatat tcaaaaaaaa atccttttac taacataaac tatgtcagta aaaggacgac
    23101 gtatcgcggt accacctttt ttcggaagtt tccttccctc aagcccaaca tctcaaaaag
    23161 agagattggc gttcgtttta acggtcgaac agttccgaat ttgcctactt atcgacaaat
    23221 tattctccaa ggccattttc agcttttctt acttgactct tctcaccagc cagagcctct
    23281 ctgcaaagtt tccaaactta ctttcctttt caacgaaatc gatattttgt tgttgggatt
    23341 aatctacatg aggaaaacta aaaagtcaag cacgaaattc aaattatttt ttctatattt
    23401 atttttctgt ttttttatct aacatttcaa taacagttcg aagatctttt ccttcagcaa
    23461 gaagtttcaa tttttccttt tcttcgacgg tataatttcg gacaaaactg gaatcaggta
    23521 tcaaaacaac gcctaatcct gctcgtgaag cagctgttgc tcctactaaa gaatcttcca
    23581 ctgcaaaggc tgaactagct tctaatcctg ttcgttccaa agctgtcaga taaggaatcg
    23641 gtgaaggctt gttctccgac acttcgtctc cgaatgtaaa cgtgtcaaag taatcagcta
    23701 atttaaagtg atccaagata tctgttgctc ttttcgtaac agtggtcgta gcaatgccta
    23761 gtttcatatg acgttctttt aagtctgcca atatttcttt tgcatatggt tttaagtgga
    23821 tggctccgct tgtcagctgt tgataaaaat attcttcacg cttcgctcgg acttcctgta
    23881 ctttttcagg gctacctgct gctttcacta aaatatcaaa actttgtttc cagttttttc
    23941 cgccccaagc gtcaacgatt tcttttggga tatggatatc aaattgctga aatccccaaa
    24001 gccagccatc acgatacgtt ttttctgtgt caactaacaa accatctaaa tcaaatattg
    24061 cacctttcat ctatacatta atcctttcca aaacaataca catagtttag cacgactggt
    24121 ccaaaaataa cagaagcaaa gaaccagcct tctcgtttat aagagttctt ggaatcgatg
    24181 gatatagatt ttcttcacag ctgtcacaag cgccagataa gcgatgactg tagcaaataa
    24241 ccataaccag taattgccag gaagtggcat caagcctaat tcagcaccaa aacttgtaaa
    24301 aggaaggaca gaaccgacaa taattcctaa tgtagtgata acaaacatgg caaatgttac
    24361 gttgctttgg ataaatggta ctttcggtgt acgcagtgca tggagcacta aggtttgtgt
    24421 ccatagtgat tcgacaaacc atcctgcatg gaataatgcg atgaaaatca cttgctgtga
    24481 actatccaat gtatggaaac ttccgccaac tacagcagga caaataacaa aatacatcaa
    24541 caagtaagta gtaatatcaa atatcgaact tgttgggcca aagtaaacca tgaatttccc
    24601 aatactagat gcattccatt tttttggctc gtccaaatat tctttatcca tccgatccca
    24661 tggcaaggaa atgcaggaaa catcatagat tagattcaaa aacagaagtt gtaaaggcag
    24721 cattggtaaa aatggcagga acatacttgc aatcagcacg gaaaacatat tgccaaaatt
    24781 agaacttgct gtagccttga tatatttcat gatattccca aaagtttctc gtccagaaag
    24841 aaggcctctt tccaaaatcg tcaaatcttt ttctaaaagg atcacgtctg cagattcttt
    24901 cgcaatatcc acagctgtat ctacagaaat accgatatca gccactttca ttgcaggagc
    24961 gtcattgata ccatctccta aaaatccgac agtatgacca tttttacgta aagctgtcgt
    25021 caaacgtgct ttttgctgag gattcaattt tacgaatact tcatggtctt cagctacttg
    25081 tgctaattca tgatcactca tttccgagat tttctcaccg gtaaccaatt cattgatctc
    25141 tagacctact tgacggcaca ctgaacgtgt aactaattcg ttgtccccag tcagaacttt
    25201 tacagctaca ccatgttctt tcagagcttt caacgcttgt ttcgttgttt cttttggtgg
    25261 atcaaggaaa gtaagataac caatcaaaac catgtctgac tcatctttga ctgaaaattc
    25321 tccaacgacg cttggattgg tcttttgtgc gacaccaatc actcgtaagc catcttcatt
    25381 aagtgactgt acttttgcaa gtacggcttc ttttcgttct tttgttaatg gtgtaacagt
    25441 accgccaaga tcaataaatt tagaaatgtt cagcatttct tcaatcgcgc cttttgtgat
    25501 catttgtgtt ttaccagctg gatcagcaac cacaacactc atacgacgac gttcaaaatc
    25561 aaaaggaatt tcatccactt tttgataatt gatcttatct gtatctaaag tttctgttgc
    25621 ttcatcaatg atagccacat ctaacaaatt tttcagccct gtttgatagt agctatttag
    25681 atacgcatgg cgcaaaacac gatcatcttc atttccttca caatccatat gatattcaag
    25741 aatgatttta tcttgtgtca atgtccccgt tttatccgtg cataacacat cgattgcacc
    25801 aaagttttgg atggcattca aatttttgat cactgttcct tttttggcca tcacacttgc
    25861 tcctttgacc aaattcgtcg taacgatcat tggaagcatt tcaggtgtta gaccaactgc
    25921 tacagatagt ccaaaaagaa aagcttctag ccaatcccct tttgtaagcc cattgatgac
    25981 gataactgct ggagccatca atgacataaa tttgatcagt agcatggatg ttttatggat
    26041 gcctaattca aagcttgatt gaattggttt ttcagatagc gtttctgcta catgaccaaa
    26101 tagtgtttca tttccaacag aaacaatgat tccttccgca cttccactta tgacattact
    26161 tcccataaag acaagatttt cgtaacttgt ttcgctttgc tgatcgtctt cacatacttt
    26221 cgcatgcttt tctactggat agctttcccc tgtcaatgct gcttgggaaa tgaataaatc
    26281 ctttgcggac aataaacgca tatccgctgg tatcatatcc cctgctgaaa gccgaacaag
    26341 atctccacag acgatttctt ccataggaat ctctgtgtac tttccattac gttttacagc
    26401 tgccgttact ttcacaagtg atttcagttt ttcagccgct tgattggaac gtacggactg
    26461 aatcaacgtc attgtcccgc tgacgatgac catagtgaag ataatggcta caccgaaaag
    26521 atctttatct ccaggagctg ctaatacata ttccgtgatg aatgaaataa ttcctaatgc
    26581 gatcaacact aatgtaaatg gcgtgatgta tgctttcaat atttctacga tgaatggtgt
    26641 ttttttgcca tatgaaatcg cattttcacc gtaattttct cttgaacgtt cgatttgttc
    26701 ttctgtcaat ccatttgctg atgcgtggaa tagttcaaat aattcttgtt tcgtttttcc
    26761 agcaaaagct gcatagattt tttgtgtatc tttctttttt tccatctcaa tctctccttt
    26821 gtgtccaaaa gacagctgtt ctcgctgctt ttggtcttta gctattcatc ggatcgatag
    26881 agaaaaaact gaaaggggct gagaacagat agataatagc cttggccttt cctctagatc
    26941 cttgtttttc gaatgactgt catccatttg ttctcatctc ctttactaag taattttaat
    27001 tcatgacttc caatcatttt tcgaatagtt attttcccaa ttagaccacc tcctttttat
    27061 ttttcaccga tggggatttg cggcaacaaa aaaacctctc gccaaatact cagcgaaagg
    27121 tttgaaaaag catattaaaa aaagcttctc agatctcatc gttgagtttt gacactgtac
    27181 aacgtaaaaa gcagatacct gcttttagct accttatgaa aagccttatc tcgacaattc
    27241 ctgttctacc cattggcgtc tctcgacgtt tttgggcagt agcctatgtt tgtataggag
    27301 cctcacctaa caaatcttat tcggttttcc ttcgttaata taacaactaa aaaagaggat
    27361 gtcaaatcaa ttttccatgt ttttcatact ttttttaaaa tacacacgtt atattcctgt
    27421 ctcacgcggt tttatttgtc tcattttcca cctcccgcta taatagaaat atagtaggaa
    27481 acgaggtgct gttatggaaa gaacacttgt tattatcaag ccagacggcg tgagacgcca
    27541 tttagtcgga agcatcattc aacgttttga agcaaaggga ctggccattg ctgaaatgaa
    27601 gtttgaaact atgactcctg aattagcaaa agaacattat cagcacttga ctgagcgcag
    27661 tttttttgat gaactgatcg attacatgac ttccggtcct gtcgtttatc ttgtgctggt
    27721 cggcgaggaa gtgatcgata tcgtccgtaa gatggttggg gcaacaaaag ctgtcgatgc
    27781 tgttccaggt acgatccgag gagactacgc gctgccgggg actgaaaaca tcattcacgc
    27841 ttctgattcc cgtgatgctg cggtaaaaga gatcgcccgc tttttcccgc cattcgatat
    27901 aaacaaaccg tctgaaaaag cggcgaagtg atacaaattc taaactgctg gtctagttgc
    27961 tgggttcagc aatggccagc agttttttct ctaaggacct ccgttgattc tttcctaaca
    28021 tatattcgag cactgtgaag aattcttggt agtctttcgt ctttttttcc cctaaagcag
    28081 cagaaatcaa tctttgataa taatctgcca tcaatgtttc atagatcact gtacttcttt
    28141 ctttatgtgc taagctccgt ttcatatctt cattcacact acgtgccttt ttcaaccgac
    28201 cattttctat ataaaacgaa gtcaggttca ttaaaaaagt aaagagatac tgctcatgat
    28261 tgttcaactg tgctaatcgt cgcattcttt ttttgatttt caaataattg ttctcaatga
    28321 accgatcact gaatatccaa ggaaaatcag ctagaataga tagttcaaat tgaccatagt
    28381 ctggtatctg catcaagtat tcttcaatga ttcggcattc ataacgtaaa aattcaaatt
    28441 ctgtctcaga tacttctgtt ttttcgacca tgtgaagact caaaaccaaa taatacagat
    28501 cttctgtttt cttaaaatgc ctacggttat tgctgatctc tttataagga tcaaagctgt
    28561 cttcttgtac ccgatctagc attcgtcttt ttttctttaa ctttattggt tcatccagct
    28621 ggtttcgcat ccattcatat tctgcaagtg tcatgttcat tcgctctaaa aatgatctca
    28681 atgttacaaa tgacattttt ttcactgaat ttgtctcaat cccgactaga gaagtcttag
    28741 aacagattcc ttccgctaat tgggactgtg tcaacttctt gttgactcga agtttcttga
    28801 tcaattcacc atcatacata atagttctcc tttttaattt aaatttttcc acattcaata
    28861 aatagatacg ttaaaaagga aaaatacacg aaaaaaataa aaaaatgttt ttttcataaa
    28921 aaataccaac cttcaagcat tagaatgttg tctaactact gaaggttggt ttgattgttt
    28981 attgattatc tttttgctgt tcaacgtctg ttcttgttac tggatataag ttggttgttg
    29041 ttttattgcc attttttgaa aagacacttg tcgaatgttc gcctttttgc ttttcgatgg
    29101 ctatgttacg ttctgcttca tttttatagt catatttttt cggatcgatc gtttcaaatc
    29161 cgtttggcac ataaaaacgc aagagatttt cttgattcag cttatctgaa agacttaaag
    29221 cagatttgac tttttcctga tctttggaaa tttcctcgtc gattcctgct gctttcgtat
    29281 cgatgatttc tcctgtttgg ttattgtaag cttttcctcc taagatggtg tatttgggtg
    29341 tcacgaagtt cccatttcga aaagccacta cttgatcatg ctgaggagat aataaatccg
    29401 taccaaaatg gagatagtct ttatcatcga ttcccaagag atgaagtaat gtcggcaaaa
    29461 catcgatttc tccaccgtat tcgtgattga ctgacccttt agtataacca ggtatatgaa
    29521 tcattaatgg cacacgctgc atttgtgcgt tgtcaaattc attccatgta tctgggtctt
    29581 ttccaagagc acttgctaag tctttattat ctgtatttga gatgccaaaa tgatccccat
    29641 aaatcacaaa gatcgaattt tggtaaatag cggatttttt caggtacgta aaaaattgtt
    29701 ccaatgactg atccaaataa tgtgccgttc gaacatagtt atctactgtg ctatttccag
    29761 tgttcaaaga tggaaaatcg aaattcttat catccgtata ataaggcgtg tgattggtta
    29821 cggaaaggaa tttcgtgtag aacggctgtt gtagatgttc aagatattgg gcagattcac
    29881 tgaataaatc tttatctaat attccataac ctagcgtttc atctgattca tcaaaataag
    29941 atcgatcaaa gaaattgtca taacctaagt ttttatatac atgatctcta ttccaaaaac
    30001 tagctacatt cccatggaaa acagcgcttg tatagccttg cttttgtcca aggatcgctg
    30061 gtgcggcttg aaagacatta tctgacccaa gttctgtgaa taatgagcct tgaggtaaac
    30121 caaatgtgcc agtttccaac atattttcag catcacttgt ctttccctgt cctacttcat
    30181 gaaaaaaatt atcaaagctg atcgttgctt gattctggaa aatactattt aaaaacggtg
    30241 tgacttcttg tccgtctacc ttcatattaa tcaaaaactg ctggaaactt tctaaatgga
    30301 gaacgatcac atttttccct ttagcgatcc caaatgtttc gggatttggc tctgcataat
    30361 gtttctttgt ataatctaaa acttcatcaa tcccattact gcttgcatgc gcgcgaacac
    30421 tgctagtcat tcctgttttg attccatcat aaatagtata cgcatcgatt cctagatatt
    30481 tgacaatata tgaacggtca aatgttcgct gcagcaattg tggacggttg gcttcgctca
    30541 gcgctagatt tcctgaaaaa ataagccctg aaagacaggt cacagcgata gccatcggtt
    30601 tgctgacagg ttgacttttg ataggtattt tcttgatcgt caaccaaacc agtatcccaa
    30661 tgaacgtagc aatatccagc cagtagagga catcatgggg tttcatcaaa gaaaaggagc
    30721 ttcctgataa cccttgcgac actttcgaaa atcccaatac agatttgact gtaatgaaat
    30781 ctgtgaattc ccgataaaaa ataatgttca agtacaacaa aagcgtgttt aaaatatcaa
    30841 tgatcaaaag aatggctaat gctggctttg gctttttaat atacaaagaa aggccaaaaa
    30901 acaataaggt agttgcaatc gggttgatcc acaagataaa gtactggatc gtaccttcca
    30961 cacctaacga aaaatctgca tagtaagcaa taatcgtctt catccagaaa aagaaaacag
    31021 ctgtcaaaac gattgctaaa cgattttggc acaatttttt aagttgtgtc acgtatatca
    31081 cttctctcta ttcacatttt tccttatttt gctcctgaaa aatgaaaatt ccctaaaaaa
    31141 gttgttatct taagattttt ttattctttc taaagattat tccgtgcact tttcacagca
    31201 taaaaccgct gtgatataag cgattgaaac agtaaggtga taaaagtctt gtcgcagctc
    31261 ctgtttagtt gatgcaggac agctttttca caacttcttc tttaaacggt gttctcctgc
    31321 caactcctcg gccacaagtc acaatattta taaaacatga gaagctgttt tttgaaattg
    31381 ttccttgtgg ctcagagtta aacggcaagc tcaagacctc ttgatacacg gtgttcaatc
    31441 agctgacctt cggtattagc tcaaaaaacg gcaaaatatg aggaactatt ttgccgtttg
    31501 tttctctaat actcaggtca aaacgctgat ttcacaacct ctgtttttca ttgtccatag
    31561 gattgatatt gtccttgtga tgactcattc gtaataattg aggcttgatt ttcttcactt
    31621 cccgttatcg tttgtccact gccagaatct gaaggacttg ttcctgtcga ctcgtttttt
    31681 tgagaagaga cagttgtttt cttgacttgt tcatttgtct ttttccattc cgctaaacga
    31741 tcggcgacca cttttttgtc tactttttca gaataagcgg tgatcacttt tccatttttc
    31801 aaacgggcta ctttgtcgcc atcatgagtc aaaagcaaaa cggtcaaatg cttgtcttta
    31861 aattgatatt gtctgagaga aatcgcacta agtacgtcat cgatattaat aaattgattt
    31921 tcttcttttc cttttggcaa atagatgtcc aattcgcctt tttcgtaatt ggcagttatt
    31981 ttatactccg cccaccaata agttgagaat tcttttttga aattatctac tgattctttg
    32041 cttgctacga ttttttctgt ttctttctga gcaagatctg ctgtcatttt tcctgaaaat
    32101 gctgcggata aaataagcag taagaaaaaa ccgaataacc aaaagagaag aaacggtctt
    32161 tttttcctca tgctttcctc cactcctatt taattttgac tattctatta tatacaaaaa
    32221 atgaaataga aagacaaaaa agttgaaaaa gatcgtaaat aattgaactt ctttttcaca
    32281 aaatggtaag aatggagaat ttcacgcatt tgctctcaac tattctttct taagcctcaa
    32341 atccgttttt atctgatacg tctttgaacc agtgacccga ttttttgatt gttctttttc
    32401 catcttgtgc taagtctact gaaataaagc catatcgatt cttatatgca ttggtccatg
    32461 accagttatc catacatgtc cacatatgat agcctaaaca attggcacct tcttgaattg
    32521 cttgatggac atatttcaga tgagattgga caaattcgat ccgataatca tcgtggatca
    32581 tgccatcttc tttgataaat cgtgcttcgt tttctacacc cataccgttt tcagaaataa
    32641 agcagtcgat atttccataa tgatctcgta cattgatcaa aatatcatag attccttgtt
    32701 catagatctc ccatccgcga taaggattca ttttacgacc aggcatttca taattgtcga
    32761 aataatcctc aggcattgga ccgtttttag tatcgattgg tgtttctttt gcttttaccc
    32821 ggcgtggctg gtaataattg atacctaaaa gatctactgt attttctttg atgaccgtca
    32881 aatcctctgg atggatcaca ggcatgagat caagttcttt tactatctca atcaattcac
    32941 ttggaaactc gccttttaca gctggatcaa ggaatgaacg attgaagaac gcatctgcta
    33001 tttgcgctgc tttaacatct tcagggtttg attcgtctct tggatagctt ggtgtcagat
    33061 tcaagatgat accaataaca ccaccttgct ccatttcatg gtaagatttg atggctaacg
    33121 ctgaggccaa cgcttcatga tagccaactt ggatcgcttt tttcatatct gactcttctg
    33181 gataatgcca tcgatataaa taacctgctt cgactggaac gattggttca ttatgagtaa
    33241 accatttttt tactttcgaa ccgaacaatt caaaacaact tttggcatat ttttcatagg
    33301 cttcaaccgt ttctcggttc aaccatccgc ctttttcttg cagatacatc ggcatatcga
    33361 aatgatacag attcacaaag ggttcgatac cgttttcaat caactcatca aaataacgat
    33421 gatagaaacg aacggcttct tcgttgattg ttccagattc atcaggtatc aagcggctcc
    33481 attggataga tgttcgaaat gaattatgcc cagtctgttt catcaactgt acatcctctt
    33541 gatacttcgt ataaacttgt gaagtttttt caggtcctac ttggtcaaag aacttttgcg
    33601 gttctttttt gtaccaataa tcaaaaatgt tctctccttt tccatcacct gaaatccttc
    33661 cttctgtttg tgggccactt gctgcagaac cccaccaaaa atttgctgga aattgatatt
    33721 ttttcatcaa agcacctctt tttctttttt agttcgtttt agttgattcc atgtatgata
    33781 ttttccatca caattacttt ttcattttct tcctcttctt ttttgattcg tttcaacagc
    33841 tgttctgcgg cttgttcccc gattttatct gttggtggtg taatcgtgat tttcggaagg
    33901 atgctcaaat cgtttttatc caaataatca taatgactaa acgcaatatc cttcccgatt
    33961 ctgatacctt cttgattgaa acattcgata gcaccgatcg acatattata attgctgaca
    34021 aaaatcgctg ttactccttt ttctaataat tcttttgccc cataatagcc actttttcta
    34081 gaatagtctc ctgtaaagac ctctaattgg atcgatggat cattttgtac cgcttctttt
    34141 gctcctgcta aacgttctct tgctacgtag tctgtttgag tggcagcaat aaatccgatt
    34201 tttttatgtc cttgttcacc atgatgagcg atcacttttg ctacactttc tcgatcattc
    34261 actaatattg tatcaatacc tgctggtcct tctgggcaat tcaatgcgat aactggaata
    34321 ctcatttttg tgagcatttc aaatccagac cactcttctt cggataagaa gacaatcagc
    34381 ccatcgatca catgcttcat caggtattca attttttgtt caattttttc tggctgatcg
    34441 gcaaacccgc ttaataataa gctataccca ttttcttcag ctactctttc gatccctgag
    34501 acaacttccg acccaaaacg gctggaaatc ccgtttatca aaagtccaat agagaagctt
    34561 cgattattct tcaacccttt agcaatgatg ttttctttat agtccaacgc tgaaatcgct
    34621 tctgctattt ttttcatgtt cttttccttc agttgctgac cattcaagta acgggaaact
    34681 gttcccactg aaacaccagc catcttagcc acgtcacgga tcgatgccat acattctcac
    34741 tcctgccagt tacatttgat ttctctttct tgttgttcga ttatgatgac cgctttcttt
    34801 gcatagtgtt gcttgtcatc aatatccata taactaaagt cttcagtaga gcaacttcct
    34861 ctcactatta attatactta aacaagtatt tgaaccggtt catttttaat atagcatttt
    34921 tttaaaagat tgcaacactt ttttaaaacg ctttcctaaa atggcgaatt ttttgccttt
    34981 ttaaaatttt attctaaaat ttactctatt tgtgggtgtt ttgtgcgttt ttctcttcca
    35041 tccgtttgaa gttttacttt ccaatggtat aatttcttta tcctatcaaa tgggggaagt
    35101 attttgaaga aattaatcgt actatttatt ttgtctgcgg gacttttgac attgactggc
    35161 tgtaatttgt ttggcggctc tgaccaatcc tcggatgaaa caaccgattc ttctgtctta
    35221 aaagcggaaa aagcagatat cactaacagt gtatatacgc taaaagtacg taaagatatg
    35281 gatttatccg cgggacagtt gacatttaca gataaaaaaa tggaatggac acgcacgtat
    35341 cagacacaag aaactgattc ttctgaatca tctgaagaaa aaacagtgct gacagacatc
    35401 aagattacta ccaaagatga cgaatatatt atttcaggaa aagaaaataa aaaagaagca
    35461 accatcacat ttaccaaaat cggtaattac cgtttgaagg atgaggatgg caacatctac
    35521 agtctatagt gccgtctgtt ggatcttctt ttgtttctcc ccttcttttc tgctatagta
    35581 aagaagcaag atgattgtaa aggagacgaa atggatgatc gatagtcctg attattgtac
    35641 atgtaataac aacaaaaata tccatacaga atttaatgac caaggaagct tgagcatatg
    35701 cgacaactgt cacaaactag tcaaagattc atttaaaaca tttgaatctt atcctgttca
    35761 aaattatgta aaaagtagaa gaagataaac aaatccaagc aaaactcact atggctgatt
    35821 tttatgaact tcaaactcag cttcttcctt tgatcaagct tcatcagtaa aacaaacagt
    35881 ggatcatttc agtttacaaa tcaaagagta aagatttatt tatttcaaat atttgaatat
    35941 aaaataacca aacgatagaa aggcttattc tacatcacgt agtaattttt ctttcccgtc
    36001 gtttggtttt ttatttttag cctaattctt gaccttttgc atgctggtta tccgtaaaat
    36061 attttccagc aggctttcct tccaattcag ctagtttttc ttggatctga tggatcacct
    36121 tttttgcatc ttctggattt tctacaaaat cgaatttatc cccatccact tgtattttag
    36181 gacatacatc aaaatcttca taccattgat tatagcgggt gttcaacgtt tcataatagg
    36241 tatataacgt ctcatcgctt tctagctgtt catagtcacg cccacgtttt ttgatacgtt
    36301 ctagcatcgt gtccaaagaa actttgatat ggaccatcaa atcaggccgt ttttttggag
    36361 caacatcatc taactcgttt agcatcgtat ctaataagct atcgtactgc tgtacttcga
    36421 tatccgttac ccgacctaaa tcagcgttta gatggaacaa caggctatct tcatagatgg
    36481 atcggtctag cacattgtca tcgttcacta aagcattttt cattgctaaa aatcgcttgt
    36541 tcaaaaagaa gatttgcaat aaaaaagcgt actgctcagg atttgaataa aagagcggca
    36601 atacttcgtt atcttcgaca ttttcataaa atggtttaga atcaatctct tttgcaagca
    36661 tatccgtcaa actgctctta cctgcaccaa tcgttcctga aatcaaaatc actgacatac
    36721 aacccttcct cttctataag tactcgccta cgtaagtttc aacaggcaat gtttcaaaat
    36781 catattcacg tacagcttgg tctgatttta aatacgtatg gagactttgt gtaatcatca
    36841 agttcgtagg taccgtctct tcttgtacaa tgatcatcgg ttttttcaac atagttgcca
    36901 cacctaattc gtaagccgtt cctggatcga ttgtttgatg ctcaaagtca aggatagcaa
    36961 caacaaattc tgcatttgtc agttcttcca tatctttttc gtatacttcc tgcgcccatc
    37021 cagcgctgaa tagttcataa ttgctttctt ggtgatgacg tggagagtag aaacttgtga
    37081 ctgttttgtt ttcctccaac gctttttcga tacgacttac tcgatcgatt tgctcctctg
    37141 aaaaaaatgg tcctgctaaa tatatttgac tcattatttt gcctccttca ataataactg
    37201 atttttaata gatactgctc gtaattcatt gaccagttcc aatggattgt tggaaaagat
    37261 tacttgatcc aaccattttt tatccataaa atcctctttt gcaaaagttt ctaataattg
    37321 ttgcaagccg ctgtaataac cgccaatatt caatattccg attggcttgt cgggcgtcag
    37381 accgattgct atccaagaaa gaagttgtga gaattcctcc aatgtaccta gacctccagg
    37441 gaaaacgagg acagcatctc ccttttcaaa taataatacc tttctttcat cgatcgtttc
    37501 tgtaggaata aatgtagtaa catcttttcc aggcaattca gtttcaaaaa gcccattcgg
    37561 atagatacct gtgacttttc cgttattttc cagtactgtt ttactaatca ctcccataat
    37621 cccggagtat gaaccaccgt aaaccagttc gatttcttct tgtgccatgt attttcctaa
    37681 cgtttgcgca ataaatttgt aactttcttt attaccaaaa cgggaaccgc aaaaaacagt
    37741 aagtttcata aaaaaacact ccctaactca aaagtctatc ttcattctac acgtgttttt
    37801 ttaaaataaa agactagatt ttgtagtttt ttagtggtat ataggataga caccactata
    37861 tatagtattt agaaaaaaac atttttcagc tattttatag ataaaacaaa aataaataac
    37921 gtgttttcat cgatgtgaaa tgacttactt atagaagata ctgggatttc gtcctatatg
    37981 ccaataacgt gtattatttt aaacaacaaa tacttgtttc ttttattaac gaaaaaatca
    38041 ttttgttctc gtgttatgtt tcactgataa atgatgtttc tctaaataaa aaagccgacg
    38101 aactaaacga tcaaaatttg atcatttttg ttcatcagct tctcctaaaa atctttttgt
    38161 taacgataaa tagctggatt tgtaaaaata tcacttgaat cgtcactgct ggaagaaaat
    38221 tcagtgataa ccgcacctgt tgcgcctgcc tggaactagt gtttgatatt gggctcgaac
    38281 gtgtactgat ctctagcatg aagaataatt tcttttttta ctgtataata actttctttc
    38341 ctttttggaa tagtacagga aagttttttt gtttcctttc cttcgacata aggtatacca
    38401 gaccctttcg acaacgaaag gttctcattt ttccttcatc gtcatttcaa ggagggtgcc
    38461 gatgctctgg acagtttcga tcgctcctaa accaaaatct gtatattcga ttctttctaa
    38521 ctctgattct ttcataccat tcctgcctca aggtacatct attgtacttt tttcttgtaa
    38581 tccactctgc ctctcctaac taattgtcaa atcatcccaa gatatgtctt cttcctcttt
    38641 ttcttcttgg atgatttctg cattcggatc tactggtttt ttcaataata aaatggttat
    38701 tcctgtgaca aaagaaccag ctaacaatgc accaatgaat gcccatggtc tggtcatcgt
    38761 agcgactgca aacattcccg atgccggaat acggctatct gcgccccaaa acatgcttaa
    38821 tccgccacct actgtcccac cgactcccgt tgctatgaca ttgcgtgcca agtcgttcaa
    38881 tacgataggg aaacatccct ctgtgatctg acagatcccc ataggaaaag cggtcttcaa
    38941 tgtatcgatt tcttgacgat tgagtatatt tttacgaatg attttcccta agaaataagc
    39001 gatcgtcaag ccgaatgggg ttaccatcga agctaaaatc aatacagtga ttggttcata
    39061 gattccttct gaaaatcgtg ccacaccccc ttatccagaa taaatggtaa tccagaaaca
    39121 gccgtgtatc tgcggtaata agcctaacca aacgaaaaat atgagaagct atttttgttt
    39181 ggctgttctt attacttgat gcagggcagc tttttcacaa cctctttttt tatttatgtt
    39241 tcataatcaa tatggtaagg atgcagctcc gtatggtaga ccgcctccga atattcaatc
    39301 atttccccaa tttgcgtaga cgatttccgt atccgtttga tgccgatctg tgcgtctgtt
    39361 ttcagaattc cttgttcttc ttctgttaaa aatactgccg agaaatcatc agaaaatgag
    39421 tcaatagtat atcctttttt cgtcagcaaa cgatacaaag attctttgcc aaattcttct
    39481 ctgctgaatt gcatcatttc ttgtggaaga taatgaacaa aataaatata aggctgattg
    39541 ttcaaataat ataagcgctt aaaacaaaca gcttgctcac cgaaaaagga aaacaaagga
    39601 tcttccttct ttatatggac caattgcaaa tccagcgttt ctttccggac ttcatatcgg
    39661 gagttctcca agatttgcgt aaagcttgcc gctttggata atcgattgta aggacgattg
    39721 cttagaaccg tcgtcccacg accacttttc tttgcgacat attcatctga tgccagcagt
    39781 tcgattgcct ttcggacagt gattttgctg acttgaaaca gttcttctaa ttcactttct
    39841 gtcggcaaca tcgaaccgac tggatatttt cctgagaaaa tatcttcttt aattttatct
    39901 gcgacttcca agtatagtac acgtgtcctt ttcataacgt caccctttgc tttactatta
    39961 ctaaaagaat agcacataaa aaataaaaaa agaacacaaa tcacatgtga gaagtgtgtt
    40021 ctttttcatt cagctgcttt aattacaagt ttacgccatt tgaggcaatt acttctttat
    40081 accaatcaaa agattttttc tttgatcgat tcagtgtccc atttccttca tcgtctagat
    40141 ccacatagat aaagccgtaa cgtttactca tttctcctgt tgatgcactg acaagatcga
    40201 tacatcccca aggcgtatag cccatcaaat ctacaccgtc tgctactgca ttagccatcg
    40261 cttcgatatg acgacgtaaa taatcgatcc gataatcatc aataatcgtg ccatcctctt
    40321 ccatatgatc aatggctcca agaccgtttt caacaatgaa taatggtttc tggtaacgat
    40381 tgtataattc attcaatgcg attctcagcc cttctggatc gatctgccag ccccattcac
    40441 ttgcctcaag aaacggattt tttactcctc ccagcaagtt cccttctgaa gttgctgctt
    40501 gtggatcagt ctcattgatt gccgtagaca tataataact aaatccgatg tagtccactg
    40561 gatattcttt tagcaactgg aagtcttttt ccgtttgctc taatttttcc ggatcgactc
    40621 catatttttt atgggtacgc gctgtgtatg cagggtattc tccacgtact tggacatccg
    40681 tgcagaaaaa attgaattct tggttttgga tcattgttgc tgcctgattg actggattgg
    40741 catcgatgct gtaagttgtt gcatagataa tcatgcagcc gatttggata tccgaacgca
    40801 attcgtggcc gatttttacg gctttgctac ttgcaacgaa ttgattatgc catgcttgga
    40861 aaatattttg gtactctcct gctccattgc tttttactaa tccttgactt aaagctggaa
    40921 agtgaaaggc cgaattgatt tcattgaaag tcatccaata tttgacttta ctgctgtatc
    40981 tctctaatac tgtctgagca aatcgttcat agaagtcgat cagttttcga tttttccagc
    41041 caccgtattc ttttgccaaa tgaagaggca tttcgtaatg agaaatcgtg atcacaggtt
    41101 caatatcata ttttaagcac tcatcaatca gctgatcata aaattctaat cccgcttcgt
    41161 taggagtacc ttcgtctcca tttggaaaaa ttcgtgtcca ggcaatcgaa aaacgataac
    41221 atttgaatcc catttccgca aacaaggcaa gatcttcttt gaaacgatcg taatgatcga
    41281 ttcctcgatg attcgggtaa atatattttt cttgatcaat cgtccagtca aattcttcac
    41341 tgccgataat cgcaaagcgc tgcttacctc caggcatagc atctgcaacg gatagtcctt
    41401 ttccgtctcg atcataagcc ccttctaatt gatttggcag cagttgctcc accccataaa
    41461 aatttttctg aaaaacgtga ttgcatcctg atttcctcct tattttacaa ttgccagaac
    41521 atcttcgttt gcaataatct ctttttggtc taattcaagt atatcggcaa atgcatcagt
    41581 attcgtaatg acaactggag tgattacgct atagccagct gctctaattg cttcgatgtc
    41641 aaaacgaatc aataaatctc ctgctttgac gagatcccct tgtttgacta agatctcaaa
    41701 gccattccca tttaattcta ctgtatccat cccgatatga atcaaaatct ccgctccgtc
    41761 agtcgttgtg atccctacag catgtccagt tggaaaaata gtcgtgatct ctccgtctgc
    41821 aggtgcaact agttctccta cttctggatc aatagcgata ccttttccca tcacgccaga
    41881 agaaaaaact tggtctggta cttcactcaa tggcagtact ttacccgtta aaggactttt
    41941 taaggtatgc cgtgctgaag taatcggttc tcctgcattc gcatgtttgt tttctaattg
    42001 attgtcttgt gtttgttcgt caaatcctaa aatcaatgta cctacgaatg caagaacaaa
    42061 agcaattcct gtagctatta ctgctactgt cacatttgac tctacaccat ccaccgtatt
    42121 aatgaaagtc ggaatcgtca ataagctgac caaactgctg gagaaagctt ttactccgga
    42181 aaatccgata atagctccac caatacctcc agaaatacaa gcggcaatga atggtttctt
    42241 caaaggtaat gtcacaccat acacagttgg ttcagtgatt ccaaataacg aagtcactgt
    42301 agaagaaatc cctaatgctc gaagtttcgt atcttttgtt cgcaatgcta cagctaaagc
    42361 agccccacct tgtgccaaga tggctggaag aagcattggc atcaatacat caaacccata
    42421 ttgttcgata ttcaaaaaca tgatcggtac gaatccccaa tgcatgccga acatcacgaa
    42481 tacttgccat aaacttccca tgattagacc tgctacgatt ggactaaatc cataaatcga
    42541 gttgaagaga ccgcctaaag cattaccggc aaccgtcccg attggtccta aagcaagaaa
    42601 tgttaatgga accatcacta ctaaaacgac aagcggaact aaaatcattt gcagaaattg
    42661 cggaatcact ttttttacga atggctctaa tttactttga acccatacgg ctagaatgat
    42721 tggtatgaca gaagaagtat aaccagatgg tgaaagaatc actgggatcc caaagaaact
    42781 gatagcttct cccgcaccag caactgctgt gatagctgga tacacaagtg ccatagcaat
    42841 tgctactgct aaaaactggt tggctttgaa ctttttagct gctgtaaaag caagcatgac
    42901 aggtaagaag gtaaagacac catctgctgc agcaaacaat atttgataag taccgctatc
    42961 agctgtcagc cagcccatca ccgttgccaa tgataagaat cctttcaata ccccggcggc
    43021 tgccatcgcc cctagaaaag gtgtaaatat actagagata atatcgatca gacgattcaa
    43081 aatatttttg gactcttctt ttccatcctc cgaaactgca agaccttcct catccacgat
    43141 cgattgataa acatctgcta cattactgcc aatcactact tgatactgac cgccactttg
    43201 tacgacttgg atcacgtccg ggtcttcttt taacttttgc gtatctgcta aagattcatc
    43261 ttttaatctg aatcgcaacc gcgtagcaca atgtactaaa cttttgacat tcttttgtcc
    43321 tcctaccgct tcccatacac gacgaccaac tgcttgatta tccattgttt tttccttctt
    43381 tcttttttat ttaaaaaata aaaacccaga ttgaaaaaaa cagtcacaaa cattcgtgaa
    43441 cctatttttt caatccaggt tttgcctgcc atacagtaac aatccttatg attggatgct
    43501 ttttttctca cttactactc tttgaatatg aatcgttaaa taaatctgct ctgcgatccc
    43561 catttcctgt ttttgcgttt gtcgaagata ctcattgatc cgttcgacac aatgaaacgc
    43621 ttttggatac tttccttgaa ctaatgcgta gagaaattca tcttgctcgt cagatccttc
    43681 ccctttgaga taacgctggg caaaaaactg cagatgagta atgatacgct gataattcaa
    43741 agattcttca tcgaacacga tgccgaagaa tttactgatg atactcagta tatctcttac
    43801 cattgtggta gcggtcatcg tcacttgcat gtcttcgttt ccttgttggc tattcacaaa
    43861 atgaaaggca ataaaaccgg cttcatcctc agaaagttcc acacccgtct tttgtttcac
    43921 gaacaaaaga gcctctttcg ctgcttgata ttctttcgga taaaattttt ttgtttcaaa
    43981 taataatgga ttaggcagtt ggatattttc ttttgctcgt gtgatcgcat aatgaagatg
    44041 atcggtcaat gtcagataaa tattaggcga aaattcaact tttagtttat cttcagccag
    44101 ttcgactact tgtttgaccc attcgatctc ctctgccgga atatcagcca tcagctgctg
    44161 gaattggttt ttagcaaaag aatctcttaa aacaaattct ttttggaccg cttctggcga
    44221 aatctcgtcc ccaatctttt tttgaaaagc tagtcctttt cccatacaaa cgacttcttc
    44281 cccgaatcca tttttcgaaa tgacgacatt gttattcaaa attttatcaa ttttcatttt
    44341 gcttcgccct ctcaagaaaa ataaaaaaac ctagaattcg cctactgttt cttagctgaa
    44401 ttctggtttt gcctgccgta cagtaacaat ccatttctta ttcaaaatca tcataccatc
    44461 gaatttttat ttatgcaagc cttttcatat aaaaaataaa aaaactggaa cacaagtcta
    44521 tctagaaaac aaccaaatca gagatgcacc tctttgcgtt tctctttttt tcagcaaatt
    44581 ggtttttcct tatcgattca tatcctttgg ctgtttttaa tctgtaacga cttatgtccc
    44641 agtatcctaa aatgtttttg tctctagatt gaaagcagat ctcatatcat ctgtcgcatc
    44701 ttttatcgat gtaacacttt ccagttctcc ttgtacaact agtcgcgtga cggcgtccat
    44761 gtcgccacaa gtaattagtg tgacaatttc ttttccctcg acttcattca gtaattgggt
    44821 atctgtagga gcaacttttt ctttaaaaaa tgttttgtat gtatacacat tttctaaatc
    44881 tgtcaaatag atcttggcac ccatctctaa attttctagc ggtgtaaaca gcaattcagg
    44941 gttcgttgca cgatggcttg ctaaggcata atttcctttt cccatttctt gatctggaga
    45001 taatgttcct gctccgtaaa gtagtgacgt attatccaag cctttgaaaa ccggtaaatt
    45061 gattgaaact gaagggactg cgatactagc aatcactggt agatctgttc ctctcatttg
    45121 cgacctcatg accccttctg tcgtcattgg ttctaccgca tcaaagtcaa aactgacatc
    45181 tttatcgtta ttctttttca gatcttcttt tgttacattc gctatagcat atttatctcc
    45241 tgtctctctg acaaaataat ccttgatctg ttcattgaaa atcaaagcta gtcctactaa
    45301 taacaagagg aacaagagga tattgactag ccatcttttt gcttttcctt tttttttcat
    45361 tttctctccc tccagactca ttttactgtt tttcttttgc tctttccaac agccgaatga
    45421 cacatttcta caactctgtg tatttttttc gtacacctgc gcttttttct acaggatatt
    45481 tcaaattatt tttgatcaat ttttcttcaa tgatctcatc tagatccagg tgaaggttgt
    45541 ctgccatcat gtatgaatag atcaatacat ctgccagttc ttctttgatt cgttctaatt
    45601 gtgtttcttt tacttcttcc ggcgttttcc attgaaaaag ttctaacaat tcagatgctt
    45661 ccaaagaaat agagatagcc aaatcttttt cgttatgaaa ttgtcgccaa ttacgttcat
    45721 ctctaaactg gttgactttt tccatactat tcatttgctt gccttcttcc aatcacttct
    45781 tacttgatta atcataccat ttttttacat aaaaaataga tgatgctttt aaaaaaactc
    45841 ctgttttctt ttatttaaaa taaatgtcat agaaaatcaa taatttaggt agccaccatg
    45901 tgtatgcagt agcgtgtctt cttcccttga ggctttttgt ttttcgatac gttcttcttc
    45961 ccaaacagac aacgctacta gaatctctct taatgatttt ccttcttcgg tgagcgagta
    46021 ctctacttta ggcgggactt ggttataggc ttttcgatgg atactttcat cttgttctaa
    46081 ctctcttaac tgctgggtca gcattttttt tgtgatcgta gggatttgct tgcttctcca
    46141 cgcctaaaat aagcgatatt gctcttccct ttatctggtg taagcaaagc agttagcatt
    46201 ttgacgatcg tgggttccgc ttttcacttc ttatctactt agtatcatga agtatacttt
    46261 cgtactaata ctaagtagcg gaagtgtcaa ctactttgtt taactacata gcaaaagaaa
    46321 cagaagggtg acaacggtca tcacgcttct gtttcttttg aatatgctgt gttgttgtct
    46381 ctatctccgt gtagactttc ctcaaactta tcctttgaca gtaagtcagt aggctgattt
    46441 gctctttcta gatgccagat acatttctac aaaaaaatag tgattctgtt ttgaaaattc
    46501 gatttttagt tctgcatttt cgtaaacatc caacattttt ttcgcactgt atagacctaa
    46561 cccgccattt tttttagagg tttttcctct tttgaccatc tccgatagcg tcaaattcgt
    46621 tggatttgcc ttgttcgcta tactaaaacg tgatccctct ttttcttcca gcagattgat
    46681 cgtaatcgga ctctgatcgg ctacacgatg atcgaatgcg ttagaaataa aaatagataa
    46741 acagcgaata aaaacaacca gatcaatcgg gattgttttc acttcgacag gaataactac
    46801 ttggatcggg attttctccg attctgcttt ttctagaaat tttaaaaaga cacccctgac
    46861 agctggggat acaatatttg ttagctgttg tatttgcggt ttttcaaaaa tagctgcaga
    46921 atgatcttct aatatttcta aaaattccaa cgtttctttt ttattttcct gaagagtaat
    46981 ttttaatgaa aacagtagac ttttataatc atgtttgaat tcctctagat gatggtaata
    47041 ttcttcattt atttgataca gttgaagcga ttcctgatgt tgtctttctt ttacttggaa
    47101 actgatcaac ataatggaaa aaaacaaaga aaaaaaactg atgactatcg acaaaagaga
    47161 tagaagcaga taattagatg agcggaagtg aacacttccc aataccaagt aaatcacgcc
    47221 ccagcttaat aaaatacaaa tacctccaaa atagtgttca gttggataag taaaaagcaa
    47281 gttgagaaat ctcgtctgtt tgtctatact ttttactaat agatagaaaa taaatgcgat
    47341 aagtagtgca aaaaaacttg ctgttccaag atgtctcttt cctaaataat ccatcagatc
    47401 aaaaaccaga aaaaagctga gtccagtgat agcaaaaaaa agattactga tcaaacagct
    47461 gataaacagg tttttcgtag taaaataaaa aagaaacatc aataataagc caactaggta
    47521 aggaaagctc actttaggga taggaagtaa aagtgtcacc accatcaaag ctatacaacc
    47581 aaagctgttt tttactagca gttgtttcga aaagaataaa tagataccta aatctaaaat
    47641 caaagtaaag gtcaaataaa gtgtcactgt tgcgaccatc ttattcctcc attgttttgt
    47701 ttcaaaatgt acacatattt ttttaatagg agcctgcata tgaaaaagta ttttatcata
    47761 gaagataacc agtttcacag cgaatggatc atcagagaat tggtcaatca tcatatcgag
    47821 aatatcgtgc agctcacttc tatctctcaa atcaatcagt tgatccagtt gggcactatt
    47881 gataatcacg atgttttctt tatcgatatc gacttgaagc aatcactcac aggtattgat
    47941 gtcgccgaac aaatacgtaa aaaaaatgca catagtaata ttgttttttt caccgcttat
    48001 acgaattttg cagtagagat catcaatcgg aaaatccttc cgattggata tatcagaaaa
    48061 gacaggaatt tatctgaaca aattcgtcaa gtgctagaac agatcaattg gaaagaacag
    48121 cagatcgtaa atgtcgataa aatctttatt gatcaaaaag gtggaagtct cgtcctgtat
    48181 cctcgggaaa ttttatatat tgaaagtatc aaaggtttga aaaaccaagt tatggtcaaa
    48241 acaactacag aagataaatt agtgaatact tctttaaaac aattgaagac agagttagaa
    48301 aagtatgctt actttttact tttaaaatct tactgtatca acttatcgca attgcagaaa
    48361 attgattctg ctcattatgt gttagaattt ttcaacggtg actccttact cgttggtcga
    48421 aagatctttg aaaagacaaa ggaacgtttc catgacttcc aaaaaactgc ttcgagttga
    48481 tgaataagag ctgagacgta agcatagcag atttcaggga gtgggccttg aatcggctcc
    48541 actccctgaa atcgttgata tgattttacg cttcctcttc tgtaggagca tctgttaacg
    48601 accatgtgaa tgttgaaacg tagttgtcta cagcataatt ggatacagga acaaataatt
    48661 ccactgattg tctcccttgt tccacattct ctcctaatga ataaatccat gtgccaatcc
    48721 cttcatttgc tcctgcagtt actagatcta ctgcctgatc tgctgggatt tcgattcctt
    48781 cagcgccagt tccagaaacg gtagatggca ttccactgct attagttgcg ctatttcgaa
    48841 tcacggcgtt tttgaatttc acctttgaac cagttagttt attcgtatca gatgttgtac
    48901 caataaattc tgttcgtttg actgataatt tccaaccggc ataatttccg cttttatccg
    48961 ttacttgtac gaaattctgt acttgtgttt gtgctccagt actgtccgtt ccgctttgta
    49021 atgcagcata tactgttttt gctgtaccta acttgattgt tccaaaatca agatctggag
    49081 cttggtcaat cgtcagtaat ccggatgttc cctgatttgg ttcgtcaggt gtaaaaggag
    49141 tatcaggatc atttggatca acaggaggaa ctggaacaac gtcttcagga tttgcagcat
    49201 ctggtttggt cacagaaatc gttccttctg tagtggctga gctcttattc tcagcaaaaa
    49261 cactttgtgt acataataat agacttccag ctagaacggt acttaatgca attgtttttt
    49321 tcatttcttt ttccttcttt cttttaaaat aaataatcca gcaaataagc caataagaat
    49381 gactccaaca agtatcagcc atcgccagtc aaatgtttct ggctgatttt ttaaatcaat
    49441 atccttttca ttcaattggt ccgctgcatc atcagttatt tcaaaatcgg tatggagatt
    49501 ccagcgtttt tctttccaag cacccttcac aaccgcttga taatgtcccg gagctaattt
    49561 ttttccttct aatgggacaa gtaaatcaaa atttgtattg ggtgctacat ctattttttc
    49621 tttttttatt gaaaggtaag gctcttttgt ttcttttttg tagatttcaa ccgatgtagt
    49681 caagccgaac atataagaag catttggatt ttgaagattc gccttaatca catttcttcc
    49741 atcgctttga tccgcataag ctttttttaa tttcaaatct ggggaagact ctttttcgct
    49801 atttcaaatc aagattgctt tcacttgaga aaactgattg acgacaccaa ctgtactttt
    49861 gttagaaacg ttctcttttt tttcttgaaa cgtgatccct cctgcgacca caccagccag
    49921 ctctttttct ggcgctttca gtgaaagtgt ctcagtgacc gcactttgag gaggaacagt
    49981 tatttctccc actgtttttg ctaagttttt catatcataa cttaatgttt catcaaattt
    50041 actttttgat tctccatatt cgatcacacc gtttgaattc gtcgtagcgg agtggatcaa
    50101 tgtctcaact gttactgatt tatctgttcg gttaaagacc gtgtagggga tttcctgtgt
    50161 tttcccaggc tccatcctta catttatata tgttttgttc ttatcaatct gattagccgg
    50221 taattcaaaa tctaccgcaa aattgaattc ggaggcatgg acaggtgtct gccaaaggat
    50281 gaatccaagg agaaggatca taagtaaaga gcagttgttt cgatgacttt tattccatat
    50341 tcgattcatc aatcatcctc cttgatcttt attctgtcgg cgcatctgct aatgtccatg
    50401 ttatctctgc tgagtaatta ccagctatct gattttcttt ggttaagaca agtttaaacg
    50461 cccgaccgtt atttaaatat tctgaataat ctgcttgcac attcgttgaa ttttgtcctc
    50521 tgacaatttc cagttcttct tcattcacta attgatactc ctctcctttc ttgaaatata
    50581 ggacatcctg catagaaaat cctgcatcat ttgtgaaagg ctgagataat tttatcgtta
    50641 agatccacgg atttttcgtt tctcgctgat cataaatcca taatttttcc tgtatatcca
    50701 tttggccaaa tgcttcttgt gtcaaaccag ttgctttgat ctgaccaaaa tcgagtttgg
    50761 aaggggcaag aaatgagaga ccaccttcta ctacgatctt cgtagcaggt gcaaaaggcg
    50821 gggcatcatg ataaacaact ggcgtatcac ttggattgtg attcccaatt tcatcgttgg
    50881 tacttggctt gttctgcaca cccttagcag tagcttctcc tgcttggtcg tttaatacaa
    50941 tttctaatac atctcctgca aaaagttgat tttctgggat agaaagaaca aattcccctg
    51001 tatcatcaat agttgtttct gacaaaacag cttgattttt tttcaatgaa accaaggctc
    51061 ctgcttcacc tgtacctgtg atcgtgcgag aagctgcatt gatcaatgtg gtacttaaat
    51121 tagcaggttc aggaggaatc acatcgactg tcgttttggc agagtccagt tctgtcactt
    51181 cttggccacc tcttactttt ttagcagcaa caacttgcac ttgatcctcc gtttttaatc
    51241 tctcatcatt gggtacttga acttcgaaca agccgccttg ttcgccttct ccccatgggt
    51301 tatatcctgc cccttcattt tcatctgttt gtccttgcgt gagagcagta atttctacag
    51361 atgatttcgt cgtatctgcg taagtaatac gtaaagtcac ttctacttcg cctgtccaag
    51421 catctcttgg ctttgcctcg acaccttcgg gaacaacgac atgcccatag atttttttat
    51481 ctgcattcgt tggcactctt aaggattcaa tcatcgggag ctgattattg gcactgattc
    51541 gattataatt tttcattccg gcacctgtct gagcaaattc atttgttaaa cctgcactag
    51601 ggcttgatac gaaattgcct aagtcggtcc cattgatcga taagtctgtc atatcagaaa
    51661 aataatccgg gtctttttca aagttatcga atgttgcgcc tgtttttcgc cataaagcga
    51721 tttctgaatg ggcgatcttt aaagaagaat ctccatttcc ttggaatacc cagccgccta
    51781 tgccattggt ctcgcttcca atccgtttgt tttggaaatc aaaataggta ggagattcta
    51841 agtccacatt caacacatcc ccactgatga tgccggtctt atcttcccct gttttcccga
    51901 ccatgactaa ataagttttt tcacctgccg taaaatttaa atcaatatct ccagttgtat
    51961 ctacagttgc tccggaatct gcgcgtatat cgatatttga tttttctcca gtgactgtaa
    52021 aatcagctga acctggactt tctagaaaac cagaagcgtc ataaaattgg atcgcttgat
    52081 ttccttgatt gagtctgttc acgtaagatt tgccatcacc tgtatttctt accctcaatg
    52141 agcctccatt ggttactgtc agcttttgcg taccattctc aaaacgaact gcgctggaac
    52201 gcccactctg cttatcgatg tcgataactg atccggctcc ttctacgatc aaagaaaggc
    52261 cttttcctac aaaacgcatc ccattgttcc cgggttgatc gtcatctcca gccattttga
    52321 ccgagatttg tccaccactt gatacatgga tttgactaga atctccttgc aagcgaaatc
    52381 cgcccgtagt tgctgtattg atggtgattt tcccaccatt cgatacagtg actttcgatc
    52441 ctgaacctct catttggatg attccgcgat tgttgtcatt ggtaatattg atctttgtat
    52501 ttaccgaaaa ttcgcttccc gaaccactga cttcaaacat gacattacca ggtagcgtat
    52561 cgactgcctc tccttcatcg ctaacgccat ctgcccgatc ataatcaaga gagacctttg
    52621 aaccgcttaa gatatggatt cctggcgctg tttttccact accagtctca tctcctgaat
    52681 ctagaaaacc gtagaatttc cctagatacg gtccataaag ttgactacca ttgatcacat
    52741 tcaattgata gcttctacaa aaataggctt tacccggagc ggcattcagt ccttccttca
    52801 ctggttggac atccaacaca ccggaaacac catctaatgt gacagttgca cgaggagcgt
    52861 aaatcagtcc taatttggac ccatcataca aatcaagtgt cccggtaaat tttatttctc
    52921 ccgtaaaatg atatctgctt ccccaaaaat cggtcatata agcaatgata atggcatttc
    52981 catcgatatt tggtgtcaat ccacctggat gtgcagctgt tc
//
LOCUS       DACDAF010000010        50186 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.010, whole genome shotgun sequence.
ACCESSION   DACDAF010000010 DACDAF010000000
VERSION     DACDAF010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.010"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(111..629)
                     /locus_tag="IVZ69_000529"
     CDS             complement(111..629)
                     /locus_tag="IVZ69_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP8182645.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(631..1248)
                     /locus_tag="IVZ69_000530"
     CDS             complement(631..1248)
                     /locus_tag="IVZ69_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAP8182646.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(1245..2099)
                     /locus_tag="IVZ69_000531"
     CDS             complement(1245..2099)
                     /locus_tag="IVZ69_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8182647.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(2096..3007)
                     /locus_tag="IVZ69_000532"
     CDS             complement(2096..3007)
                     /locus_tag="IVZ69_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8182648.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(3048..4382)
                     /locus_tag="IVZ69_000533"
     CDS             complement(3048..4382)
                     /locus_tag="IVZ69_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP8182649.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            4590..5420
                     /locus_tag="IVZ69_000534"
     CDS             4590..5420
                     /locus_tag="IVZ69_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HAP8182650.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(5664..5913)
                     /locus_tag="IVZ69_000535"
                     /pseudo
     CDS             complement(5664..5913)
                     /locus_tag="IVZ69_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(6104..6298)
                     /locus_tag="IVZ69_000536"
     CDS             complement(6104..6298)
                     /locus_tag="IVZ69_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182651.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(6803..6988)
                     /locus_tag="IVZ69_000537"
     CDS             complement(6803..6988)
                     /locus_tag="IVZ69_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182652.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(7838..8179)
                     /locus_tag="IVZ69_000538"
     CDS             complement(7838..8179)
                     /locus_tag="IVZ69_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP8182653.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(8179..8409)
                     /locus_tag="IVZ69_000539"
     CDS             complement(8179..8409)
                     /locus_tag="IVZ69_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016178973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP8182654.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            8696..9034
                     /locus_tag="IVZ69_000540"
     CDS             8696..9034
                     /locus_tag="IVZ69_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182655.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(9239..9478)
                     /locus_tag="IVZ69_000541"
     CDS             complement(9239..9478)
                     /locus_tag="IVZ69_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HAP8182656.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(9454..9801)
                     /locus_tag="IVZ69_000542"
     CDS             complement(9454..9801)
                     /locus_tag="IVZ69_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF159 family protein"
                     /protein_id="HAP8182657.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(10533..11114)
                     /locus_tag="IVZ69_000543"
     CDS             complement(10533..11114)
                     /locus_tag="IVZ69_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP8182658.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(11297..11923)
                     /locus_tag="IVZ69_000544"
     CDS             complement(11297..11923)
                     /locus_tag="IVZ69_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP8182659.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(11945..13276)
                     /locus_tag="IVZ69_000545"
     CDS             complement(11945..13276)
                     /locus_tag="IVZ69_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HAP8182660.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(13431..13832)
                     /locus_tag="IVZ69_000546"
     CDS             complement(13431..13832)
                     /locus_tag="IVZ69_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP8182661.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(13918..14124)
                     /locus_tag="IVZ69_000547"
     CDS             complement(13918..14124)
                     /locus_tag="IVZ69_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182662.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(14219..15721)
                     /locus_tag="IVZ69_000548"
     CDS             complement(14219..15721)
                     /locus_tag="IVZ69_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HAP8182663.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(15739..16194)
                     /gene="argR"
                     /locus_tag="IVZ69_000549"
     CDS             complement(15739..16194)
                     /gene="argR"
                     /locus_tag="IVZ69_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP8182664.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(16292..16909)
                     /locus_tag="IVZ69_000550"
     CDS             complement(16292..16909)
                     /locus_tag="IVZ69_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182665.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            17130..18503
                     /locus_tag="IVZ69_000551"
     CDS             17130..18503
                     /locus_tag="IVZ69_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP8182666.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            18578..19690
                     /locus_tag="IVZ69_000552"
     CDS             18578..19690
                     /locus_tag="IVZ69_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HAP8182667.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(19762..21399)
                     /locus_tag="IVZ69_000553"
     CDS             complement(19762..21399)
                     /locus_tag="IVZ69_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HAP8182668.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(21567..22175)
                     /locus_tag="IVZ69_000554"
     CDS             complement(21567..22175)
                     /locus_tag="IVZ69_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP8182669.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(22559..23710)
                     /gene="queG"
                     /locus_tag="IVZ69_000555"
     CDS             complement(22559..23710)
                     /gene="queG"
                     /locus_tag="IVZ69_000555"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HAP8182670.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(23729..24481)
                     /locus_tag="IVZ69_000556"
     CDS             complement(23729..24481)
                     /locus_tag="IVZ69_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182671.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(24622..25572)
                     /locus_tag="IVZ69_000557"
     CDS             complement(24622..25572)
                     /locus_tag="IVZ69_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HAP8182672.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(25573..26412)
                     /locus_tag="IVZ69_000558"
     CDS             complement(25573..26412)
                     /locus_tag="IVZ69_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP8182673.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(26409..27155)
                     /locus_tag="IVZ69_000559"
     CDS             complement(26409..27155)
                     /locus_tag="IVZ69_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP8182674.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            27393..28763
                     /locus_tag="IVZ69_000560"
     CDS             27393..28763
                     /locus_tag="IVZ69_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8182675.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(28818..29714)
                     /locus_tag="IVZ69_000561"
     CDS             complement(28818..29714)
                     /locus_tag="IVZ69_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP8182676.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(29995..30672)
                     /locus_tag="IVZ69_000562"
     CDS             complement(29995..30672)
                     /locus_tag="IVZ69_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP8182677.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(30763..31668)
                     /locus_tag="IVZ69_000563"
     CDS             complement(30763..31668)
                     /locus_tag="IVZ69_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP8182678.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            31843..33297
                     /locus_tag="IVZ69_000564"
     CDS             31843..33297
                     /locus_tag="IVZ69_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8182679.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANVATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVVPSH"
     gene            33313..34344
                     /locus_tag="IVZ69_000565"
     CDS             33313..34344
                     /locus_tag="IVZ69_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HAP8182680.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            34351..35538
                     /locus_tag="IVZ69_000566"
     CDS             34351..35538
                     /locus_tag="IVZ69_000566"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HAP8182681.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            35694..37076
                     /locus_tag="IVZ69_000567"
     CDS             35694..37076
                     /locus_tag="IVZ69_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP8182682.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            37048..37434
                     /locus_tag="IVZ69_000568"
     CDS             37048..37434
                     /locus_tag="IVZ69_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182683.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(37634..38302)
                     /locus_tag="IVZ69_000569"
     CDS             complement(37634..38302)
                     /locus_tag="IVZ69_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HAP8182684.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
     gene            complement(38491..39288)
                     /locus_tag="IVZ69_000570"
                     /pseudo
     CDS             complement(38491..39288)
                     /locus_tag="IVZ69_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(39569..40948)
                     /locus_tag="IVZ69_000571"
     CDS             complement(39569..40948)
                     /locus_tag="IVZ69_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HAP8182685.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            complement(41123..42292)
                     /locus_tag="IVZ69_000572"
     CDS             complement(41123..42292)
                     /locus_tag="IVZ69_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP8182686.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            complement(42267..43418)
                     /locus_tag="IVZ69_000573"
     CDS             complement(42267..43418)
                     /locus_tag="IVZ69_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HAP8182687.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            complement(43378..44739)
                     /locus_tag="IVZ69_000574"
     CDS             complement(43378..44739)
                     /locus_tag="IVZ69_000574"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HAP8182688.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            complement(44736..45737)
                     /locus_tag="IVZ69_000575"
     CDS             complement(44736..45737)
                     /locus_tag="IVZ69_000575"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HAP8182689.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            complement(45753..46448)
                     /gene="dapD"
                     /locus_tag="IVZ69_000576"
     CDS             complement(45753..46448)
                     /gene="dapD"
                     /locus_tag="IVZ69_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HAP8182690.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            complement(46454..47170)
                     /locus_tag="IVZ69_000577"
     CDS             complement(46454..47170)
                     /locus_tag="IVZ69_000577"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HAP8182691.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            complement(47167..48048)
                     /locus_tag="IVZ69_000578"
     CDS             complement(47167..48048)
                     /locus_tag="IVZ69_000578"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HAP8182692.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            complement(48051..48851)
                     /gene="dapF"
                     /locus_tag="IVZ69_000579"
     CDS             complement(48051..48851)
                     /gene="dapF"
                     /locus_tag="IVZ69_000579"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HAP8182693.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            complement(48838..50097)
                     /gene="lysA"
                     /locus_tag="IVZ69_000580"
     CDS             complement(48838..50097)
                     /gene="lysA"
                     /locus_tag="IVZ69_000580"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HAP8182694.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
BASE COUNT        14343 a        10384 c         8934 g        16525 t
ORIGIN      
        1 caaaacttaa gttattaaga caaatgaata aacaactacg ctttcctcga aacaaaaaaa
       61 taaagcacaa atgcgcattt acgcactcat gctttattcg tacaattaat tcagataacg
      121 gcagcgcata ggatgccaat aacacttcct aaaatagctc ctcctaaaat gtcagtagga
      181 taatgtaaaa gtaaaaaaat cctcgaataa gcgatcaaac aagcaaataa aaaggctaat
      241 attcctgcaa ctggacttaa ttcgaacaac gcagctactg ataaaaaggc tagcgctgta
      301 tgtcctgaag gaaaagaaga agtcttcggt ttacttgtgt aaaggacaag ccgacgattt
      361 ttttcataag gtcttttccg tcttgtcgtt tttttgataa aaagcaaacc aacaaaaaaa
      421 tagatcaaac tgccgataag aatggctaga ccatattctc tagtatcagg tatcaagact
      481 aaaacagcag caaggagcaa ccaaataaaa ccaccattag agatattact gataaatttc
      541 aaaaaattga tttttcgact atccgttttc cgttgcttgg cgaacttgtt gataatacta
      601 tcatcgattt tagcaatcaa acgcaacatg ttattcctcc tttttaagaa ccttttcttg
      661 cgtacgatgg ataaaaagca ggacttgaaa ataaaacaag aaactgaaac ctaataaagc
      721 aaaatagatt ggtcctgcaa accagaatgc gacaagaagg atcaacgtgc ctgccaaata
      781 gaaaagcgcg cttttgaaat cattaaaaaa caagaaaaat gcagtaatcc aagaagcttc
      841 tttttgttcc agttgaagca agattttgta actaaagaga agcgcgctta atagaagcaa
      901 aaacaacgta gtatacatca atgtatagcc aattccccca ccccaatagc ggaaaatctg
      961 ataatcgatc aatagaagaa gaaaataaac acttgctaaa ctatcttgct ttccataaag
     1021 agagaagttc tcacgaaact ttttccagaa tagtgaaccg agctttttct cttcattttt
     1081 tttgtaatga taaatcatat acagaactgt tcgacttgca gttcctaatg tgaaaacagg
     1141 caagacgcac aggaaccata gtagctgtaa atggataaga cgtggaatcc attcaatgat
     1201 ttctaagaaa taatcattgg cttttttacc aatcgatcga ttcatcatcc ttttgaacct
     1261 cctgtcaaat ccatcccttc aatgaaataa cgttgtgcaa aaaagaacag caaaatcgtc
     1321 gggatcaaga caagtgttgc tcctgccatc agataattcc attgtgtcgt tgcttggttc
     1381 tgaaaaactt gcaagccaat ctgtaacgtg tatttttctt gatcttggat atataacaga
     1441 ggacctaaga aatcattcca agctgcgttg aaggaattga tcgcaatggt aatcaaggca
     1501 ggtttcgtca atggaagcat caaatgactc caaatataca aatgattcgc tccgtcgatt
     1561 tcagcagctt cgatcaattc attattgatc gataagtaaa attgacgcat cagaaatata
     1621 ttgaacgcat tgccgaagaa cgatggaacg atcaggggca aataagtacc tacccagccg
     1681 atcttggaga ataatacata ttgagggatc atcgttacaa accccgggat catcatcgta
     1741 gaaagaacca aagcaaacat cagctttttc ccaggaaaat caagcttcgc aaatccataa
     1801 gcaataaaag aatttgaaag gacattaccg atcactacta gcacagtgat gaataatgta
     1861 tttcttgcat agcgccaaaa aggaaaggcg gcaatcgtat ccagatagtt ttcccatacg
     1921 attttttctg ggaaaaaggt cggaggataa cgaacgattt cttccattgg tttcaatgaa
     1981 gtaaacacca tccaaagcaa tggaatgatc aaaatgattc ctattactgt catgaggaca
     2041 taacttagta ttttttttgt ttgccgattc acactggtct ttttgaaata atccatcatt
     2101 tgccgtcacc tccagaataa tagacccact taggtgcaag cttcaaattg acaaacgtca
     2161 gaaccaacac gatcagaaac aggatcattg acatagccat cgcataaccc atatcaaaag
     2221 ctacgaacgc cttgttccac atatgcagat tataaaaaag caaagaattt gcaggtccgc
     2281 ctgttccatt tttcgtcatg acataagctt cttgaaaaat ttggaaagaa ccgatcgtag
     2341 aggtgatcac atcgtaaaaa ataataggag tgattaatgg caaagtaata cttttgaact
     2401 ttccccaaac gcctgctcca tcgatttctg ctgattcata taaagatcta ggaacatttt
     2461 gtaatgtagc taagtaaagt agcattgctc ctccagaact ccatattttc atcaaaatca
     2521 acgcaggttt cgtccattgt ggatcaaaca gccaagctgg tccagggata tggaaccagc
     2581 ccagaaatgt gttgatcaat cctgcagatg gagaaagcag ctgcatccat aagatgtaga
     2641 ctgctactcc tgataagact gccggtaaat agaaagctgt acggaataca ctgattcctt
     2701 tgattttttg attgagtact gtggctaaaa acacactgaa aatcgtcgtc agcggtacat
     2761 tgaagatgac gaaataaacg gtgttgtata acgatttcca aaataaatca tcgtgaacga
     2821 acattctttt gaaatttgct agaccaatga aattcatctt ggatgtcaaa ttataatcgg
     2881 tgaaactacc aataactgaa aaaagcatag gccctagcat aaataccaag aacccgataa
     2941 taaaaggcga gataaataaa taggcccatc ttgcttcttt tttctttcgg atagataaac
     3001 gcttcaaatt ttcttgcctc ctctgtacct agacagtcaa aaatggatta ttgattttgc
     3061 ttgactaagt tttctactgc tttttgtgca tctgccaatc cttcttttgg tgattttgtt
     3121 cctaaaagaa tctggtcaat ctgttcattc actaatgtcg tgtaatccgg agcatctaaa
     3181 ggaactggtg tgatcaccgt atttttaaag ttttcgtccg ccatttgata gatcattttt
     3241 cctttatccg ttaggttgtc attattcact aaattctcat tggctgtctt gctcgccatg
     3301 atatcaaaac ttttttcgcc gaatttttct tgtacttctg gagaagaaag atatttgatg
     3361 aattcataag aggcctcagg atcttttgct ccgtatggta cttccaagac gaatccgcca
     3421 ccccacgacc aatggcctga accttcttct ttttctggga gctgcatcac gccaaaatca
     3481 aaatcatccg gtgcattttc catcaaacta gagtaataat tgatattttg ggcacgcatg
     3541 gctactaatc cggaaataaa tggatcagat acaccagacc caaattcggc ttctaattta
     3601 ttgatcgtat ttttcccata ataatcttgc cagtcttgga tccactccaa ggcttccact
     3661 ttatttttag tatcaatctt gactttttca tctttgtcaa accaactagt cccgttatct
     3721 gcgtttagcg cccatacatc agcccctaaa ttccataatg gataaaaacc gatgcgtgta
     3781 aattcttttc cttctttttt atctagttta cgtgctgttt cttctaattc atcccaagtt
     3841 gtcggtagat cttgttcact gattccagct tctttaaata actttttatt ataaaaaatg
     3901 acttgtgtat ctgtattgaa tgggatcgca taaggatcac cttcatattc tactgtatcc
     3961 caaagctgcg gataaaaatc cttagaagtg tctttttcta catatttgga gagattagtt
     4021 gcttgctgtg cttctgctct ttgggcaacg gaatttatgt cctgtacaat aacatcgggt
     4081 gcatttccag ctgttattgc agataaagat ttagtccaga tgtcacccca tggctgatac
     4141 ttataattta catggatctc gttttgtgat tgattgaaat cctcaatgat ttcttcgata
     4201 gcttcttttc gtgcaccgga tccccaaaag gaccagaaat caatattttt tcttccatca
     4261 cttgtttttt cagaagaatt tgctgcactt gaactggcat cgcttgcatt acttgatccg
     4321 catcctccta ataaaaacaa tgctgaactt gccagcaacc ctgtaaacaa taattttttc
     4381 atattttacc tccaaatttt aatgtaaccg atgccggttt taatataacg atatcatttt
     4441 gttctgaaaa taacaattta taaggtatga ttctaaaaaa attattaatg ataccaatac
     4501 tttatataat tcgcgagcgc tttctttgaa ttttttaatc tttcgtagca gaatgagaat
     4561 gtattaaaaa tagattagga ggaattttga tgtttagaca ccagaaagaa ttgcagtttg
     4621 aagcaaaacc agatcgtccg aatccattaa tcgcgaaata tctgcaggag ctgatcggcg
     4681 gccaatatgg cgagatgagt gtagctatgc agtacctgtt ccaaggctgg agctgccgag
     4741 gagaagaaaa atataaagat atgctgatgg acattgcaac agaagaaatc ggccacgtgg
     4801 aaatgttggc gacaatggtt gctcgtttat tagagggtgc gcctgttgaa gatcaagaag
     4861 cagcgatgca aaaagatcca acaatcggtg ccattatctc tggaatgaat ccacagcacg
     4921 cgatcgtagc tggcttagga cctcgtcctg ctgacagcgt gggcaatcca tggagcggtg
     4981 cctatatcat tgcgagtggc aacttgttag cagactttag agctaattta aatgccgaat
     5041 cacaaggaag acttcaagta gcacgtattt acgaaatgat cgatgatcgt ggcgtaaaag
     5101 atatgctgtc tgttctcctt gcaagagata gctatcatca aaatctatgg gaatgtgcag
     5161 tgaaagaatt agaagaaaaa gaaggttcaa tcttagtccc aagtactttc ccgcgtgaca
     5221 aagaacgaaa agacattgct tatgacttct ataacttctc agagggagac caaagtagtg
     5281 aaggttcttg ggctagtggc aaagcactgg atggcgaagg cgaatatcaa tggttgaaag
     5341 aacctaagat cgaaggcgct gcaccaaaat tagaaccagt aacaccaaaa atgtatggga
     5401 cacctccatt caagaaataa atatctaccc gtagaaacac ccgttttttg ttccacacgc
     5461 tttgtgagca aaactgacta aagtcattaa tcataaccac ccttcaaaag ggtggttttc
     5521 tctagagcta taagctcaaa tcaccggcca gcgcctaaag acgctggctt tcatatttta
     5581 tgttcaagcc atattgcctt tgccagtttt gcccacctct taaaaggttt atgtactact
     5641 ccttagccct taaaaggatc gtcttactct cgtacactca gcttatctaa cgcactatca
     5701 tgtttttctt gttcttgaat gtactttttg atggtcgctt cattttgtcc tacttttgtc
     5761 acatagtatc cttccaccca aaagtgtcga tacccaaatt tatattttag atttgcacaa
     5821 tctcttgatg atctcctgaa tattggctcg atattgatta taaattattt ttcttctata
     5881 ctttggtgtg aatacaatgt ggtatttaca catctacttt gtacgggcta aactatttcc
     5941 ctttattgct ccacccgcat agcaagtggt tttgtatttc aatcgctcgg cgcgctcaat
     6001 taggtctaaa gacaataaat ctaaaaaccc gctgcttcac tgacagaaac aacgggtttt
     6061 cagaaaaaaa tgaaatgaaa aagatctctt acggcaatct attttatttt tttgattttt
     6121 tataaatgga aaatgcttca agaagtccaa gaaataaagc cgtataaaaa caagaaccta
     6181 tgaaatcttt atttattaga tattcaacag aaatcccgat aacactagcc aacaatatat
     6241 ttatcagaag tgtaaaataa ggatgctttt tatagaatag aactagtgtt gttttcatag
     6301 actctccttt cttcatattt ccaattaatc acaaattcac ggcattacta gaaaaattaa
     6361 aggggcgcag aagtggaaaa atactcttcg actttcccta caaaccaggc catcttgtgt
     6421 ttaataacta taccaaatct aaggtacctc taaatctaaa ttccatttgt ggcggtgacc
     6481 tccaattttt aactcttcta tctcccatcc agtatacata accttgatac ttcgaccact
     6541 tatatatcga acacacaaat acctatccat tgcaggagta ctacctaact tagttgctac
     6601 ttgcatctaa ataacagctg aaaagatagg acttactctt agtaaagtat ctgaactatt
     6661 aatttttaaa ctatcatttt tatcctcaac tacatgcaca tctgttgcaa cttcactttc
     6721 tgtctcatcc agataaatga ttaaggaatc gggaattgca atatcttcag ctgacgctgg
     6781 aatagttgag ctaaattagt catcatatct ttattataaa ataaccaaca gcaaaaaata
     6841 caatgaaaaa caaacttgga actaatgtat cattaataaa tgttgaaaaa ttcagcaact
     6901 cattactgta tgattttagc agcccaacca acatataccc tataaaagct aataagatgg
     6961 ttaggaatcc tttagaattt ttactcattc atagacactt ccttaaataa cttttattat
     7021 agaaggtatt gtaaataata atattgacaa aaagtgactc aaaataaaaa aaaacttaca
     7081 ttatactgga atgaactgta ttgatagtgt acctaaaagc tctactgaca taagatcgtg
     7141 taatcggtaa agtaatttta ttaattatac gggatgtaat caattagaga ataaactaat
     7201 cataaaaggt acttttacat tcataattgt cgctttgaga ttctactttg gttcactatc
     7261 tgacccaatt gcacattttc gatcattaca agtattggtg tcgttagaac aactaaataa
     7321 aaactagcgg tagatttttc agaatctatg ctaatttctg tatggatgtt ccagtgatgg
     7381 caaatttctc ttttcattgt ttttcttgtc gcatgatatg cctttttgtg ttattcagtt
     7441 aaactataga aattctttcc tagacagatc ttgatcccaa attttacgtt tttgagcatc
     7501 gatatagttt aaaatgacat tactcatatc taaagagttt agatttttta ggactaaaac
     7561 tgtcagttgt tctttttctt ctttctgtta aagtattgtc gcgacttttc gtatacgtta
     7621 agatatgtcg tgaaaaaaca agttttgtga cacaaaaaaa cgaatgactt gaggaaatca
     7681 cctcaatcat tcgtttaaaa tgctatatat tctttagttt aagatacgga aattaatgcc
     7741 atcgaccaca ctagtagaat gaacgacatt tacttggcct ttttttaatt tcgttatgtt
     7801 tagcatataa aaatattata gagtttactt acaatgctta aaacatatac tgtataatct
     7861 gatcaatttt agccatgtct tgcaatggta agttttctat ttttttgagt tttcgttcct
     7921 taaaatcaag agattttaat tgtgtaataa ttacttgtcc ttttatatct agctcttcag
     7981 gtaatgagta acgtgtcggt aaattcttta tagtggaagt aattggacat atgaccgaaa
     8041 acattgtttt acggttaaat tcataacgag agacgactag tcctggtcgt cttttttgaa
     8101 tttcttttcc tacggaggga tcaaaatcaa tccatacaat atcacctttt ttaggaatat
     8161 aaattctttc ttctgacact ataaaatttc tctcccttca ggagttaaat cttcccattc
     8221 gtctttctca taatactcgg cctcttcccc accactaaat ggatcttcaa tttttggaac
     8281 taacgtaatt gttccatcat cagaatacac aacgatatat tcttggtttt ctgaaggttt
     8341 ctttccgtta tcagaaggta aagttaccac tacagaactt ccttgtaatc tagattttgt
     8401 aacaagcatt atcatcactc ccttaataaa agtatactat ataacactaa gtaacgcaaa
     8461 attccccttt gtaaactatc tagaaaattg ttttgtttaa agtatatctt attggatata
     8521 aatagaaata aattgtagcc agttcatttt ttctttaact aaaaaaataa tccaagaaac
     8581 attgaaccta tggatccaaa agctacccaa atactatagc taaccccccg ctaccttcaa
     8641 ttttgcagat aaaacgcttt gggagaaaat ttcaaagaca acaggccatc ctatcatgcc
     8701 cgattataaa caaaaagctg gctattcctt ttgctctgac aaatttcaat tgggaaagtt
     8761 cacgaaacta gcaggtgaag aagtttcaac tgttcggatc aaagaatgcc cgcttcaaat
     8821 agaaacattg gttcaacgaa tttcaactag acaagacttt gctattgtag aacgtgagat
     8881 cgtagctatt tttgtagaag aagggatttt acatgatcca actcatatca atgtggataa
     8941 atggcaacct cttatctata aattcagaga atatacaact gccaaccagt cgttaacttt
     9001 gaattttaga ttccaagaat tcaaagagtc ataatgataa acatcgttag gtataaataa
     9061 aaaagactcg cagcacgagt aaaaaacaaa tagaagctat acattagaaa ggtcgactgt
     9121 gaccctatag atgcagtata tgcagcttat gagtatttct tctgttctct ttgtttttgg
     9181 gatctgtgct gaagtctttt tcgttttttg ccgctctttc tttgaaaaat cgattatgtt
     9241 ataccttctc cattactaat tcaggcatct gctgagtaat gatttttcgc gcaaaagaaa
     9301 tatctgttac ccaaggttcg atttgttctt cagtcaagac aagcggcatt cggtcatgga
     9361 ttggtgcgac tgtgcggtta ggttcagtag tcattatgat tgattctgcc attttttcat
     9421 cctgatggct acgataaaaa ccgccaatat acactatttt ttccttattt gaaaacataa
     9481 atttgtcttt ttcttcattc cactcattgg gaaaacacaa cgattttgca aaaatggttg
     9541 atgaaaggtc tttttttctt ctactgtctc tgcacgggca ttaatcatca attgtccttt
     9601 tttaaatccg gtaaatcccc acttcatgat ttccggagtg aggatgtttt cttcctcttt
     9661 tcttaacgtc acaacaagat ttgacggaaa aacttctcca gctgctaatt ctgctgcctg
     9721 cttcggttgt ttcgtctggg cttctcgata ataattctga aggagctctg actctagatc
     9781 aaaaaaataa cgaccacaca tcctaatccc tcccaatctt tttttctatc atacactgca
     9841 acaagaagtt cgcaccaaca aaacgctttc aatttttgta gaactaaaaa agttgtgaca
     9901 agtgacaaac tctccagtga atggtattct cctgccaact cctcggtcac aagtcacaat
     9961 attcaacaaa catgagaagc tgctttttga aattgttcct tgtgactcgg agtgaaacgg
    10021 caggcttacg acctctgggt aaacggtgtt caaaagccag tttctcggta ttaagccaaa
    10081 tttatgcaaa aatgtagaaa gctattttca caaaattttt cttaatactc gaaactaagc
    10141 gactttttca caacctcttc cttaaacggt gttcaaaagc ttgcatctgc ggtaataagc
    10201 ccaaccaaac gaaaaatatg agcagctatt tttatttggc tgttcttatt acttgatgca
    10261 gggcagcttt ttcacaacct ctccactaaa cgatgttcaa tcagctaacc ttcggtatta
    10321 gctcaaaaaa cggcaaaata tgaggaacta ttttgccgtt tgtttctcta atactcaggt
    10381 caaagcgctg atttcacaac ctctaataca cggtgttcca gaagtagctt cttcgaaaaa
    10441 taagccgaaa tttcacaaaa atttgagaag caattttcgt aaattccttc ttatttcttg
    10501 aagctgacca cttctgtcac aacctctaat tattaaagaa ccttttgcga agttaacaat
    10561 ctttctttga tcaattgaaa attctgccta agtagtgata gatcctgtgt gactttcaac
    10621 aataagatac ttccctggat ttcagcaatc aacgctttgg cttgacggtc tgcttcttca
    10681 tcggacagtt tttcttcaga aagtgccagg atattttgtt tcgtatactt gacccattga
    10741 ttgactaatt ctagtagcaa cagacggtat tcttcatcca ctgtactcaa ctcaataatc
    10801 aaattaccta caggacagcc atgataagtg atctgtgtct catgatcagc gaaaatccag
    10861 tccaacattt cttctaatgc ttcttctggc tgttttccag catttaagat gtcttcgaac
    10921 aattctgtct gccatacgtc catatgcgca tggatcaccg ctagacaaac ttcttttttt
    10981 gaagaaaagt aataataaaa ttgacctttt cctgtatcag aagctgctag aatatctcgg
    11041 attgacgttt catgatagcc ttttttataa ataagatctt tggtcgcttc caagatcttt
    11101 tcctttgttt tcaatgatat tctccttttt catttctcat agtcctatat tatacagtaa
    11161 attcatcatt ttttcttctt aatcgtttaa aaaagactgt gccaaattat ctgacacagc
    11221 cctcactata aaactgttct catatagcta gatgttcatt gattcaagaa ctgcgaggac
    11281 aaaagcaatt cctatcttat gatagttgct ctaatacttc ctctgttgtc atcacttgat
    11341 ctgcaataaa gccaaagttc gtcaacgctg catccattgc ttcttggcca ggagcaccaa
    11401 ttgcatctgt cgctaccaca acattgaatc cactctctac caattcacgc atatgggaat
    11461 cgctacacaa gtttccgttc attccaccaa gaattactgt gtcgattcca ttttttctca
    11521 attggagcgc caaatcattg ctttctggtc caaagatttt atgaggagag ctgatgatcg
    11581 tattttcatc caaataaggt ttcaattctt cgataaaatc ggctcctgaa ccttcttcca
    11641 ctgattcata ttgacttttt ctagcaaaca tctgctgctc aagcatcata tgttctcctg
    11701 caccgccaaa ttgccattta tggtcatgtg ggtaaaaata atgaggagaa ataaagagtt
    11761 tgtatccttt ttcttttgct tgttttacca tttcaatcat attttcgatc gtattgtatt
    11821 tttctaagat atcttttgtc aaaccaaagc caccgcctgc tggtttcaag aactcgactt
    11881 gcgggtcagt gagaactact gctgtatttt tattattgaa catggtggat tctccattcg
    11941 ttatttattt taatacatca tttagagctt cactcattgt cggatgagaa tagatttgat
    12001 ctctcaataa cgtataagga agttttccat tcatagctag cgaaatcaag ttgatgactt
    12061 catgagaatc ttccgcatag atacttgccc ctagaatcaa gtcagtttca gggtcgacta
    12121 aaactttgaa tacaccttta ggatcttcta atacttgtgc tttagggaca ccgcttgtca
    12181 tatacttgaa taatttgtaa ttgacgcctt gtgctttggc ttgtttttct gttaaaccta
    12241 cattggataa agtcggagtg ataaatacac tgtaaggcac agctttccgg ttattcgttg
    12301 ttcgtttatt ctcgcccttc aactgatcca taatgattcg ataatcatct agagagatat
    12361 aagtgaactg caatccgcct ttgacgtctc caatcgccca aatgttgtct gcatctgtac
    12421 gaaggtattc atccacagcg attgctccgc gatctgttag tttaacatct gtattttcta
    12481 atccaagtga tgctgtactt ggttttcttc cagttgcagc caaaactttt gacgcttgga
    12541 ttgttacttc ttggccatct tctgtaaagg tgacggcagc tgttgattct tggtctgcta
    12601 cttgatctac agatacacct agatggaatt cgattcccgc atttgtcatg tcttctaaaa
    12661 tcatttgcgc gatatcttca tcttcacgtg gaagaaattc agaatgggca tcaagaacga
    12721 caactttaga tccgtattca ttgaacattg atgcaaattc caagccaata tatccagccc
    12781 cgatgatcac taatttttcc ggtaattgtt cctgatccat cgcttgcgta gaatcaatca
    12841 agtagcgact tgtattcaat cctttgattg gtaaaatgat tggttcagaa ccagtattga
    12901 tgaaaatccg ttcgccttca acaatcactt tttcaccatt attcgtcact tcgatttgat
    12961 ggttagaaag aaaacgtgct gtaccgtcca tcactgtccc agttgcctca tcgctgatca
    13021 tatgataatt tttggcgcga agcatgcccg tcaatttttc tttccgagca acagcctctg
    13081 taaagtcgat tcctctttct ccattgaaaa tcaatgattt agaaggaata cagccgatgt
    13141 tgatacatgt tccgccatac atacgtgttg acttttcaac gactaaaacc gattcacctt
    13201 ttgaagctaa cgccttcgct aaagtcttac cgccctttcc aaaaccgatc acaatatttt
    13261 gatatttttc catcattttt ccctcgcttc ttttttacct accgattggt acaaaaatat
    13321 gataaccgat aattgtctat tctccaaatc atctgcttta tttgtcaaaa aaaaccagac
    13381 aaaaagcggt cctttcacgt ttttagtctg gttcgatttc ctttattctt ctaaacaatc
    13441 gttacttcta catcgatatt tcctctagtt gctttggagt aagggcagaa ttcatgcgca
    13501 tcttctgcaa ttttttgggc ttcttcttcg ctgatgccat cgatatgcac ttctaatact
    13561 acaccgatct gatagccgcc atcatctaaa ttataaagag agacacgtgc ttttactgtg
    13621 gactctgctg tcattcctgc ttctttgatc atatgttgta ccgccccatt gaaacaagaa
    13681 gcataacctg ctgcaaataa ttgttctgga tttgttcctt ctgcatggat tcctggagga
    13741 gtgattttca tatgcatcga gccatttggt gcctcgactt ctccattgcg cccgccatgg
    13801 ttgatcattg ctgtttcgta tgcttttttc attgtactgc tcctttcgat tgaccatttg
    13861 ctacttggct ataattatag tgtatgacaa gtaaggcgct ttctacaaaa attctgctta
    13921 ttcgaatacc agaatgccgt cttctactat ttttccaaaa aacaaaaaaa tactactcgt
    13981 gaacaacagc gtcatatttg ttccaaaata aatagcaatc ttttctacat aatcttttat
    14041 atgattgatt ttaagataca tatataccag aaagttgacc ccataaacca atactgttaa
    14101 aaaaataacc atattcgtta ccattttttc ctccttttgc tggtctccct accagcactc
    14161 gatttaacca taccactttt tttgccgtcc aagcaactag cctttcaaaa agactggttt
    14221 attctgctgt taatgattca agatcagaaa aatgtccgaa taattttgct aattttacta
    14281 acgccaactt gttctttccg aattcatcat tttctatctg taatactagt aacggctcat
    14341 gtaagcttaa acggatcaaa aaccagccgt ttccgtatgg ctcttctaga tcatatcgaa
    14401 taccttcttc attttccggg tcgaagttca tccctttttc ttcttccaac agtcgcttca
    14461 tttcttctaa tatcttgttt ccttgttcgc gtggttcatc gctgaacaat tttaatcgga
    14521 tttcttgtac ttctacgggc tgtttcaact ctttgatttg ttcatctaat gtgatacctt
    14581 ttctttttaa ttctggcaaa agcatcagga tctttgcgat gacatatgca ccatcatcca
    14641 gaaaatagtt ttccttgaat gcagcgtgtc cgcttgtttc gatggctagc tgtgtatctt
    14701 tcccaagacg gttaagttct aatgctttat tgattacatt tcgatagccg gaaatataac
    14761 gaacttggat gcctcctttt tcttcaatga atctttgtag atgagaagaa gtaggggaat
    14821 tcgtcacgat tcttgttcct ggatgctctt ttaatacgat tgtacttaat actgcgatca
    14881 aattatttcg attgatcact gttccagaag cactgacaac tgcagaacga tccacatctg
    14941 tatcgaaaat gatcccaaga tctgcttcat ttgctaaaac agcctgcttg atactttcca
    15001 tcgcttcttt attatcagga tttgggatat gattaggaaa tcggccatct ggttccaaaa
    15061 attgggaacc tgttgaatcc gcacctaagc tattcaatac tttttcagca aagaatccac
    15121 cagcaccatt tccggcatca acaatgattt tccaaccatt tagtggtttg ctttctagtg
    15181 ttccaatccc ctttttaatt tttgtgacta aatcttgcgc ataaggtgtc aaaaggtctg
    15241 ctttttctac gcttccagtt tgttcgcttt ttattttttg ctgctgtgat aggataaaag
    15301 caatatcttc tttttctgct cctccttctg aggtaaagaa ttttattcca ttataataat
    15361 agggaagatg gctagcagtc agcataaccg cagcatcgca cgagaactgt tcaaattgag
    15421 tggacataaa catagcaggc gtagtagcta attcgaaatc gatgacatgt atcccttgtt
    15481 ctttcagact ttggatcaac gcctctttca gtgctggtcc gcttatccta ctgtcatgac
    15541 caatcccaat cgtccatttt ttatttggat cggttgattt cttctttttc tttatccagt
    15601 ttgctagtcc ccagccgatc ttttttacca tgtctgtcgt caagtttact tcatatcctt
    15661 caactggtaa tgcgattcct cgaatatccg atccattttg cagcgctttc atatctttca
    15721 tataaaagtc ctcctcattt attccctcat tttttccagc ttttctgcaa atcgctgtgc
    15781 ttcttcttct gagcggcaaa taataatgaa tgtatctaca ccggccatcg ttccgacaac
    15841 ttcagggtaa gccacttcat ctagccaatt cgttaccaca tcggcaccat ttcgttcagt
    15901 caatacgata accatgaact gaacagactg gatacgcaaa acctcgcgtc taattgctgt
    15961 acgcaaacgt tcttcattta aagaaacaga tggctggtta aataatgtat agcgtactat
    16021 tttgttttca ttttgacttt ttactaactt catttctcga atgtctcgag aaatcgttgc
    16081 ttgagtcaca tcggcgcctg cttcatgcag ccgcgcaagc agctcttcct gtgtcccaat
    16141 aggttgttct gtaatgatct ggcggatcag tgcttgtcgc tgtttctttt tcatattaga
    16201 cacctctcaa tgttgattat agcaaaagat aagtaatatt tcttcatatt ttggtatttt
    16261 ttacttttat tttttgtttt cattcaggtt gctaaccttt ttctatttta acacgcaaaa
    16321 tcgtcttcat tttttcaggt gctgattttc ttggatcgct gatgtaaatc tctttgtgtt
    16381 ctttagaagc tctttcatag ccttcttttg cgatgaatgc ttctaatttc tcaaacgttg
    16441 ctggttcttc ggcatagggc ccgacgtgta agatttgggc acaaagacct tcttccatct
    16501 ttttgaatac tacttgttct ttcaagtctt ccggaagttt gctagaacgc tgaatggctt
    16561 cttgtgctat cgcttctgta acaaagtcag gctgtcggat catcaattga taagaaaaat
    16621 gttctttttt catcactggt tcatgcaaat acttttcttg cagtccccat tgtccttcca
    16681 gtggatagac agtatacatc tgataatcag gaatcagcca atttttttta ggcgacatgc
    16741 gtattgcata gctgactgca tatagacagg ctactcttcg tttaaagtct tcctgattcg
    16801 ggtcgccgat ccctctgatg ctaaagaatg attttttagg aacctctagt atttgcgggc
    16861 tttttttcat actatagctc ttgtctttac gccattcaat tttttccatt tttcttcctc
    16921 cgcgaaattc catttagtta tttattatca tacctctttt tgagtgactt ggctaatcgt
    16981 gttgacacta tttttcagtt tgtgctagaa taagtgaagt aaataaatcg tacagataac
    17041 acgtttcggc gtgtcgagag agaggcggtt tctattttta taatagaaat cactctcttt
    17101 ttttacgaaa ttttttagag gtgatgtaaa tgacaaaaca aaaacagctg cttttagtac
    17161 ctgcagtaat tgcaacaggg atgatgtctt ttgcgggcgt attgatcgag acggccatga
    17221 atgtaacttt cccaactctt atcagacagt ttgatttaac gactgcacaa gtccaatggg
    17281 taacaacgat ttatcttttg atgatttcga tcattgttcc gctgtctact tatttgaatc
    17341 gcaattttag tctcaaaaaa ctctttttag cttcaaatct gcttttcttg gcaggtataa
    17401 tgatcgattt cttctctcct accttcatgg tcctattgtt tggtcgattg ctccaaggtg
    17461 cagcgacagg tatcgctctt ccgttgatgt tccatattat cttgacattt gcccccctca
    17521 atcgacgagg cgcgatgatg ggtgtcggta ctttgacaac ggccattgct ccagcaattg
    17581 gccccactta tggaggcatt atgacttcac attttacatg gaatcatatc ttcctgtttc
    17641 ttgtgcccgt tttgattctt tctttgatta tcggctggtt tgctattccc gagatggcag
    17701 tacaaaaaag tggttatttg gattggataa gcgttttagg aatttgtctt ttgtttagtg
    17761 gaagtctaac atttttgagt acgttgggaa cagtttccag ctggattgct ttaatcatcg
    17821 gcggtattgg ctggttcctt ttttactatc gaagtaaaaa agtggagcat ccactgatcc
    17881 gactgtctat tctttcaaat aaaacattcc gcttgttttt gattggcttc ttagtttatc
    17941 agtttttatt acttggtgta tcttttgtct tgccgaattt ccttcagatc gttcaaggaa
    18001 gtagtccttt tgtcgctgga ttagcgatgc ttcccggcgc agcggttggt gctttgcttt
    18061 ctcctttttc cgggaaaatg ctggatcaat atggtccgaa gaagccaatt tttgctgggc
    18121 tgattctttc tttgattggt tggctagcat tattcctact cataggacac gcttcagtgg
    18181 gtgtattgat tgcttgtcat gtgttttata tgatcggtat cggattatct tacagcaata
    18241 tgatgaccac cggaatgaat gcactgaatg aagaactaca aggagacggg aacgcaatgt
    18301 tcaatacctt gcagcagttt tctggcgctg tggctacttc attagtagcg gtcattatca
    18361 attacgtcca gcatcatact tcccataact atgaagtgtc tactacatta ggatcaaaag
    18421 cagcattagg cgtcttgttg ctgttgcttc tcgtaagctt tgctcgattc gcctattatc
    18481 tgttctttgc taaaaaagcg tagattccat atacggcagg tgttgcatct gccgtttttt
    18541 tgtgtgaaaa tggttgtttg taaaaggagg cttttttatg gaaaaaattg ccattatcgg
    18601 tggcgggatc attggtatga ccctagccag ttacttagat acatcaaaat tcaatgttgc
    18661 tttatttgat gaagggacag gacaggcaac taaagctagc gctgggatta tctccccttg
    18721 gttgtcgaaa cgcagaaaca aacaatggta tcgtctggct aaagacggcg ctgctttttt
    18781 ccctaaactt ataaaagatt tccaacttga tcaaacgatt tacgcacaat cagggacact
    18841 tttgcttcga cctgaaaaag atttagctga attggctgtt cttgccgaga aacgaaaaga
    18901 agaagcgcca gaaattggaa acatcgaatg gctttcacct gaacagacat ctcaagcact
    18961 tccgttattg aaaccagcag tttcactgcg tatcagtggt ggtggtcgtc tggatggaaa
    19021 agcatattta gaacatcttg gtcagcgttt agcacaaaaa caaatggagc agatccaggc
    19081 aaaagtcact ttgcataaga agagcgattc ttggctcatc aagggaccgt ttggagaata
    19141 cacagctgat cgtgtaattt tgacacctgg cccggcactt aagcctttat tacaagaatt
    19201 aggctatgct gcagatatac gtccgcaaaa agggcagctc ttagcatttc agacatctta
    19261 taagatgagt caagactggc ctgttgctat gcttgacgga gaagctgatt tcattccttt
    19321 catggatgga aagatccttt taggtgctac ccatgaaaac gatcaaggct gggatttggc
    19381 tcctactagc gaagcttata agggattgac taagagtaca gaacagttct tgactgatcc
    19441 agatcagata aaaaactggc catacgagtt ccgtgtaggt acccgtgctt atacgtcaga
    19501 tttttcccca tttttcggcg tactgccaga tgatccaagc ttactggctg ctagcggtct
    19561 aggctcttct ggcttgacca caggtcctta tatcggctat ctattagcca acttcttaaa
    19621 tactggtcat tggcctacgg aagattatca aaaggacatc tccacctata ttacgaaaaa
    19681 tccatcatag aaaaacagct ttttcaagta aggatcccga gcgatattgc gcatggatta
    19741 cttcttgaaa aagctgttat tttagttcaa tttctgaatc aaattctcca aactttcttt
    19801 tgcttcatct ggcaagagat cttttcctat ctgagcttca atgaatcgta aacgaatatc
    19861 aagtcgttgt ttcaccagat ttttatagga cgtatcctca aaagaaacag gaaaatctgg
    19921 tataggtaaa tagtggatgt cttcaaatgg accaaacgac ttgaattctg ccgtttgttg
    19981 cacgattctt tcaacgattg acaatgtcgt ttcaggtttg atttttttat catcgaaata
    20041 tccagtattc aggacatagc aggctgtttg ctgtttcaaa aacaactctc gaaaagcttg
    20101 atagtcttcc ctaagaggat agacacggaa aggattagca aatggttcaa tgactagctc
    20161 atctagctgt ctttttgtag tgatattttc cgcgtctgat cgttttgttg ctaatgttgc
    20221 accaaaagac gctgctaaaa ctgggtcatt gatcttgata attggcggaa gcgaatcatc
    20281 tttcatgatc caaaaaacag catcgatctt ttcgctaaga tgatcgactc ggtcgggtgt
    20341 cgcataacgt gatttgactg tccgcccatt tccgtttcgt atatctcctg ttactaggac
    20401 tttttctcct ttacttgtac atgtcacgcc cacattctga caagtaagga aagaagaaat
    20461 ggccggatca tcagacggat agtcttgtgt tttatcaaag taagaaggtt ccaaggcagt
    20521 agcaaaacca ttttttcgag aaataacgaa agcatcgtca tgcaagatcg aaacagagtg
    20581 accttccgta tgttttgcta aggtaatcgt tgattttcca gaaccggaca acccaaatac
    20641 agccatcgta taggtctggt cattactagc atattgtttc atcccaccgt ggcaggcaat
    20701 aaagccattg cgatttccca atgcccaagc aagcgtcaaa gtcgcttttt ttaattctcc
    20761 aaagtaacgt aatcctagca caaccgctgt attatggaga gcatcaaaca aaatgagtcc
    20821 atttggaaat gtttcatgtg tccattcggg atcacaaaag atataaagat ctccctcatc
    20881 aaaggaaaca gacttttgat aagtctctaa gatcttcgaa ttcgctggct gaaaattcag
    20941 caaataagaa tacaaattgt tctcaaatcc ttctggaatc agcaaatgac tttgcacaga
    21001 aaattcttca gataggccaa cgattacttt tgtatggtaa aactggcgct tgcgactttg
    21061 atacacagct tctcttaaaa ttttctcgta tttgctttgt tccttgtcta agtcctcaaa
    21121 gatccgccga gcacttgctg ttcttcccac aatgcttcca tcattgaata ctagtgtcct
    21181 aacatcagct ggtaaatcta gttcttcagc atgtgagatt gttaaatctg tgatgatcgt
    21241 tcctggactc ccttttgcta gttgataagc tgtcttccta tcaaaaactt catgaacatt
    21301 attaccgtaa aatgtcgttt ctacaatcga tcgaatactg gataacagtg gatttccact
    21361 tgtgatttcg tttaattcga gactctcttt tgtactcatg gctcctcctc attccctaaa
    21421 caaaaaaacg ttttctttat tatacattat tcgagttttt atttgtactg ctgcgctgtg
    21481 ggaagcaaac gagttatttt tcacacaaaa aaaccgagaa cttgaataaa caagtttctc
    21541 ggtttcatca ttttcctttt atcggcttag taccagccgt ttgctaacca gaatgtttta
    21601 gcagcatccc atgaaccata acgagatgtt acatattgtt ctgctacacg ttcttgattg
    21661 gcagctgaat agtcgccgtt taagtatgaa gcatctaatt gataacggcc gatgtaacgt
    21721 ccgttagtag ctgtgtatga accgcctgat tctttttgtg cgatccattc ttttgcagag
    21781 cttgaagttg gcgctgttgc agcagctggg gcagcaggag ctacttcaac tgtttcaaca
    21841 ggtgcaacgt atgtatgttc ttgcgttgct gtttcagttg tagatgctgt attttctgtt
    21901 gttttgtttt ctgttgttgc tgaagaatca tttgaagttg ggattgttaa ttgttcacca
    21961 acataaatgc ggttgatgtt tgcgatcgaa tttttttcag caattgcatc gatcattgag
    22021 ttgtctcctg caaatttttg tgagatctta gataatgaat cacctgattt tactgtataa
    22081 acttcatcag cgtgagcatt tgtagttcct acaaacattg cagtagcacc agcagcaaaa
    22141 gttgtaccta aaacaatttt cttaaatgaa ttcatattaa actccttttt ttctccgttt
    22201 tttattcttt cgacgctatt aactttatca tttagaaata tttcataggt aaaagaaaca
    22261 tgacatttaa tgacaaaata acgaattatt taatatttgt aacatttaaa caaatatttt
    22321 tttgatacaa aaccataaaa gccttgttgt ataagcaaag taatcgtttt tctatgtttt
    22381 tttatttttg aatgaaaaac gcagattctg taacattcac tgcaataatc cataaaaaaa
    22441 agcaaaaaaa tttttgattt ttatcaaatt ctcttaaaaa aatgtaaaaa atacaaaaaa
    22501 accagtaatt gttacaacaa ttactggaca aaaactttga ataatgttaa ctattttttt
    22561 attttaactt tctccgcaat aatttctggg catgttccaa ttcgtttata acgacttctt
    22621 ctgtttcttt agctaatatt tcatctaata catcaagcca tttttccggt tcttttgttc
    22681 ctagacgtcc aatagcccaa gctgctgttc ctctgatgac agggcggaca tctgttaaac
    22741 attctgaaat ctcaggcaat gccgttcgat cacctagatt agctaaagca atcaatgcgt
    22801 ttctctgcaa aggtttcttc ccacgccatg aaccagctaa atgcccaaat tgctgtttga
    22861 agtctttatt agacatcgaa agcattggct ttaattttgg atatatttcg tctacttttg
    22921 gttccatctc ttcatgaaaa tgaaaatctt ttccttgatt gtaagggcag actaactggc
    22981 agatatcaca tccataaatg acatttcgca tttttttacg atattcttcc ggcatcatcc
    23041 cttttgtctg agtttgataa gacaaacatc gctgggcatt cattcttccg tcaccaagca
    23101 atgcttttgt cggacaagca gtcacgcagc gcatacagtc accgcaacca aattctcctg
    23161 gtttatcagg ctcaaataca atattagtaa cgatctcacc aagatagaca aatgaaccga
    23221 actcttcagt gatcaacaat ccgtttcgtc caataaatcc taaaccagct cgctgtgcta
    23281 cagcgacatc gatcagttct ccagtatcta cttgcggagc tagacgccat tcctcttctt
    23341 tttgccattt ttctgctctt gtttggatga attcgatcaa tcggttcaaa cggtctctga
    23401 gtatatcatg gtaatcgatc ccccaagaag cacgagcaaa ctgcccgcgt ttttcatccc
    23461 taggcacttc ttcatggatc ctagtaggat acgcaagtgc aatggaaatg atcgatttcg
    23521 gctgatcaaa tgtcatttct ggataaagac gctcatcgat atttggatgt tcaaagccag
    23581 aagtatggcc agctgctttt tgttcttcca acgattcttt taatgaatca aaaggttccg
    23641 ccgtggtgaa cccgattttg tcaattccta atcgtttgct ttcttgtatg atttcttctt
    23701 ttaatgtcat ggtcttcctc gcttgctgtt aacggctgta taacccataa tatagttttt
    23761 cttttttcag ctggacaaac tggatctgct gatcggcaat cttcttttct tccatccatt
    23821 tttttcttgc agcaaatact tcccaataat ttgttgaaat taattttctt ttgttatcta
    23881 atgcattaaa aaaattcaat gaaactggtt ttgtacttaa cagttcatgg agccttacct
    23941 cttcccatgg cgaaaactca gacagatcgc gggaatacaa tacttcttca tagagatttt
    24001 tttgctgtgt gtacgtgaat gtttgcggga ttttcccagg cctagcaatt tctactagac
    24061 gattataaaa catattcatt aatttgctgt tggcaataaa ttgactttta taataggccg
    24121 actggatctt tttgattact ccttctgctt tgatgactga aaataatgca ggccatgctt
    24181 tgacggttat ttcgtcgttt tgtttaacta atacgccagg tgtgaagccg actggagaaa
    24241 ggaacacaaa ataaccgata ccggtatttt catctaaagg ctgaaattca tcaaacaacc
    24301 atttgcctat gtacagctct tcatctggtt ctgttgtctc attttgattt gctatgaata
    24361 atttagctaa ttctgcttca agaaattgaa ggtcttgatc cttgtcggta ttttcctgct
    24421 ggctgatcaa tcgaaagact tcttctttaa tcgtatattt atctttacgt gtaaaattca
    24481 tagccacacc ttccttcctt actctaacta taacggaatt tcttcaaaaa aggtatctgt
    24541 acgacgaaaa acagcataat tttttttcat atctcttata aaaaatgcaa ggtctgctcc
    24601 tcaagctaga ccttgcactt ttcagctttc ttttgtttgt gacaaacctt catggatcgt
    24661 ttcaatattc catttcatca tctgatagta agaatctcct tgttctcctt cttttgctat
    24721 ggaatcagtg aacagtttat catagatttt caaacccgtt tcttttgcta cccgttccat
    24781 gcttcttgag tctacactgg tttccacgaa taaaaccggt acttcttttg ctcttatctg
    24841 atcaatgatc gctttcattt gatcaggcgt accttgactt tctgtattga tctcccatat
    24901 ataagctgct ggcaaatcat atgctcgtga aaaatacttg aatgcccctt cacttgttac
    24961 taataatttt ttgttctctt cgatagaagc aaaactttcc ttcgcttgtg tatctaattc
    25021 ttttagtttt tccacatatg cttctgcatt ttttttatag agtgtcgcat tttctgcatc
    25081 tttttcagag aatatacgtg cgatttcctc cacatatttt attccgttag ataggtctag
    25141 ccaagcatgg ggatctgctt ttgtatgttc ttcaccgcta gttaaataaa gaggttctac
    25201 atttttgcta actgcaaaat aatcttttcc ttcttctttt ttagccgttt ccatcaagtt
    25261 atcgaaccag ctgttacctg tttcaagatt caaaccgttg tataaaataa catctgcatc
    25321 gcttgccttt ttgatgtctt ctggtagtac ttcatattca tgcggatctg ttccgactgg
    25381 tacgatactg tggatatcta tttgatctgt tccgacctct tttgccatgt ccgccaagat
    25441 cgaattggta gccacgactg acaacttttc tttacttcct tcatccgctt ggtcagaagc
    25501 ctgctttccg caaccggcta ataccaagaa actaactgcc aagattaaaa agagtgattt
    25561 ttttgttttc atctatctgc ttcctttctg aaataaaatt ccttttgttg gagaaaataa
    25621 aaaagcaagg ataaaaaatg cggtacatgc taacacgatc gtagctcctg atggccaatt
    25681 gtaactataa ctgaaaaaca caccgacaac tgcacttagc ataccgattc ctgcagctgt
    25741 aatgatcatt ttcagtaaat ggttcgttag caagtaagcc gtggcggctg gtgtgatcaa
    25801 catggcaatc accaagattg ttcctactgt ctgtaaactg actacagcca ctaatgtcaa
    25861 aaagaacatc aaaagataat ggatcagcga tgtgttcagc ccataagctt ttgccattgt
    25921 cggatcgaat gatgtgatct tcaattcttt ataaaagaaa aagacaaata tcaagacgat
    25981 tccactaacg agtgctgtca gcaacaaatc gctttcccta acagctaaga cattcccaaa
    26041 taaaatatga tacaaatctg tcgcactctg ggcatatgaa atcaagataa tccctaatgc
    26101 aaaaaaggag ctaaagacaa ttccaatcgc tgtatcattt ttcaatcggc tccgctgagt
    26161 cacgaaacca atcactgctg ctgttagcat cccaaaagca gtggctccaa agatgtaact
    26221 aaaaccaaac atataagaaa tggctacacc tggaagaact gcgtgagaga tagcgtctcc
    26281 catcaaagac atccctcgta aaataataaa agaaccgatg actccagaag caagtcctac
    26341 aagcatggaa gtgaccaaag cgtattgcag gaattgataa ttcattaatc catcaataaa
    26401 ggattggatc attttttctc tcctcctttt actaaatgtc tgatgatctc accataggcc
    26461 aattgaaggt tcttcgatgt aaagacttct tgtactggac cggaagcgat cagctgttta
    26521 tttaaaagaa taacctcatc gaaatattct tctactttat gaagatcatg atggacgatc
    26581 aaaatcgttt ttcctgaatt cttcaattcc tgcaagatgt caaagatctt tcgttcactt
    26641 aacgcatcaa tccctacgaa tggttcatct aaaaagatcc attctgctcc ttgggctaga
    26701 gctcttgcaa taaaaactct ctgaagctgt ccacccgata gttcgctgat ctgtcttttg
    26761 gcatattctt ccatccctac ttttttcaaa gcttgtcttg cacgttcttt ttcttttttc
    26821 ccaggtcttt gtccaattcg taaagatgga tatgttccta aaagtacaac gcctaataca
    26881 tcaattggaa aggaaagatc caattcactt cgctgttcca cgtaggctat ttttttacgg
    26941 actgagttta ccgactgtcc agaaaaggtg actttaccag tagtagctgg tatcaactct
    27001 agcaaagatt tcataaatgt tgattttcct gcaccgtttg gtccgataat accggtaatt
    27061 ttttgtggat ttatcgtcaa gttgatagtt ttcaaaacag ttttcccttg ataagcggct
    27121 gaaaggtctt gaattacaat ggccgtacgt tccaaatctt acactccttt ttaggtttac
    27181 ctaacttttt atttaaatat agtttaacta aaatggaaag cattttcaag tagaatgatg
    27241 aaaaagtttt tttcgaattt tcctcgcatt ttatgaaaat tttctgtaga atcacatcaa
    27301 gagttcaata aggctaacct aataatgaaa aacatgtgtt gaaacgtttg attatttttt
    27361 cttgttgact caacaacgaa aggagttttt gtatggaaga agaaaagtta actcgaagtc
    27421 ttagtgcccg tcatatccaa atgatcgcac taggtggaac gatcggtgtc ggtctgttta
    27481 tgggtgcctc ctcaaccata cgttggacag ggccctcagt gatgggagcc tatgcgattg
    27541 caggattctt tttgtatttg attatgcgtg ctttaggcga aatgctttac gttgatcctt
    27601 cgactggttc ttttgcaaat tacgcgagcg agtacatcca tcctgtggct ggctacttga
    27661 ccgcttggag taatattttt caatatattg tcgtaggaat aagtgaagtg attgctgtag
    27721 gatcttatat gaattattgg tggcctgatt tgccggcaat tattcccgga atcattgtcg
    27781 tcttgtttct tatgctggca aatcttattt ctgtcaaggc gtttggcgaa ttagaatttt
    27841 ggttttcgat catcaaagtc ataacgatca ttttgatgat cattgcaggt cttggggtaa
    27901 tcttatttgg atttggtaat catggtcagg cagtagggat ttcaaatctt tggaaaaatg
    27961 gtggattctt cactggaggc gtcaaaggat ttttctttgc attatcgatc gttgttgctt
    28021 cctatcaagg aatcgaactg atcggaatga ctgctggtga agcagagaat cctaaaaaga
    28081 cgatcattga agctgtccag tccactatcg gtcgaatctt gattttttat attggtgcta
    28141 tttttatcat tgtgagtatc tatccgtgga atcaattgag tgagattggt tcaccttttg
    28201 tacaaacttt ttctaaagtc ggcattacat ttgctgcagg actgattaat tttgtcgtga
    28261 ttacagcggc attatcaggt tgcaattcag ggattttcag cgcaagtcgt atggtctata
    28321 cacttgccat aaatggaaag atgtctaaaa aatttctgaa actatctcgt cacggtgcgc
    28381 ctttttatcc tgtcgtagca atctcaggtg gaatcttaat tggtctgatc ttaaattatc
    28441 ttctaccaat gttcatcaac cagtcagaaa atattttcgt tttcgtatac agctcaagta
    28501 ttttgcctgg tatggttcct tgggtagtga ttttgatcag cgagattcgc ttcaaaaaga
    28561 agcacgcaga taaaatgcat gatcatcctt ttaaaatgcc actatctcct tatacgaatt
    28621 atgtgacact tgctttttta gctatcgtat tgattttcat gtttatcaat cctgaaacga
    28681 gaatctcatt gattattgga ctcgttttct tgctttacat gacgatccat tactttgtac
    28741 gcgaaaaaag aaccggaaaa taaaaaaaga acgaagcttc accttagtgg aagcttcgtt
    28801 cttttttatt gcttttatca attcaatttt agcgtctcac cgggagtcag gaaataattc
    28861 tccatgctca tcccattcag cgacaagatc gtttctactg gtacgccagt tcgttcggct
    28921 atttgatttg gaccttctcc ttccaaaact acggttgtcg cagcctgtga agtcgcgctg
    28981 ttggtattag tttcagagga atctgttgtg tcttgtgttg ttcgagcttg catttcagaa
    29041 gcttctaccg actctgctgt ctcagaatca gaagatgttg tgtcttgtgt gcttgttgac
    29101 tctgcttgaa gagaggcgct agtctgcaaa taaatatcgg aaatcttagc gacatgattc
    29161 gtataattag ccgataattg attgatcaaa gtatctaagt ctacaccgtc tttattttct
    29221 gctgcctgat acgctgcacg taattttctg atcccttcgt cggagattgc ttgaagctca
    29281 cgtgcttttt ggttagcaac tgctgataaa ccagctattc cctcttgatt tccctgaatt
    29341 tctgtctggt attcttcaat caatgcaggc gtcttttctt cgatcttttt cgaataatca
    29401 tttacgattg cttgaagttg ctctggcaaa ccatttgctg ttttttcttc agaagtttgt
    29461 gtctcttttg ttttagttga tgactcactt gtttgtttcg tctctgtttt ctttgtcgtt
    29521 gtttccgtta tggtcgtact tttcgcttct gacgaatttt ttccatgaaa atatagaccc
    29581 gcaactcctc ctgctatgat caaaaacacg gcaactgctg ccccaatcat gatcatccgc
    29641 ttacgagctg cttgtttttg ctgtcttctt cgggtcatcc gaacattttc tccccactca
    29701 ttttcatcat acattttttt caccaccaat ttttatgtat aatagcgtta tcaaacgctt
    29761 catattctta ttgtagcaaa taattgtcgc tgtgcacatt tttatctttg ttatttataa
    29821 gaaaatttca ccagttgaga tgattccaag attgtccgtc gatttctcct tgcagctgca
    29881 ttgttcgttc gtctatctca gccatcagtt tctttatttc atataagagc gcacggtctt
    29941 gatattctga tttttcgctt aattcatcta attgttggat cagccaatca tttgtcataa
    30001 tgaagttcct ttcatttctt gcagtgtaaa ggtcaagtct tcgatctgct cttttgcctc
    30061 agtcagtgct tctacgatat atgcttgttt ttcagattct tcttcctgca ttttctgatt
    30121 ttcctgtact ctttgaataa accagtcaat ccgctgagtc agcgatggtt tgccttccaa
    30181 tgagagatac tgctgataag caattagctt ctcccaacgt ttttcctggg ataaatacat
    30241 aaattgtgct aaaacgaatg gcggaagata ggtcatatgg aatttatttg cgattcgctg
    30301 atacggcctc aaaaattcgg aaatcgtata ttcttctttt cctccagctt ggtattcttt
    30361 ttccgccaca cctgttgtca atacgattcc tagttctttc ccttttaata catgtgctgc
    30421 tcgttccaag acattatctt gccaaatttt taaatgagca ggagaactat accagtaaaa
    30481 cggaaactgg aaaatgatcc gatcatgctg ggccaagagc tgtagttcag tctctatatc
    30541 tatttttccg tctggataac ttgattccaa atgatgccaa gtagctggta aaccagcaga
    30601 agcttctttg aaaaattgct gatttaaaga ttcttcgatc gttggatggc taatgatgat
    30661 aagtgtacgc atcccttttc ctccttttta gtcttcgctt tacagtgtag cataaccgcc
    30721 acaagtttct tttgccgatg cttgtcattt taaccagact aatcaggttg tccaagaaac
    30781 tgcggtttgt ttttccaact gttttttcaa ggtatccaaa gcaatattct taaaattttc
    30841 gtttttcata cgtttacgat agttcgtagc cgtttctccg gtactctttt tgaacattcg
    30901 gctaaatacg actagactat tgaaccctac ttgataggca atactttcca cggattcatc
    30961 cgtcagagaa agaagaaacg cccctcgatt gatccgtacc ccgatcaaat attccttgat
    31021 actggtaccc atatgatttt tgaatactcg cgacaaatgg ctccgattga ccgctaaatg
    31081 ctgggcgatt tcctcaacag acaatttttc agcataatgt gcctcgatgt atttgactgt
    31141 ttcaacagct aaagaggaat gaaccttttg tacaccaccg ctgacctttc cgccatcttt
    31201 taaaaggact gataaaaaac ggtaggttaa tgctgttaac tgtaattcat tttccaaggt
    31261 ttcttccgta tctttcatgc attctaaaat aatgtcgata tatttttgta tgtcagaaga
    31321 gaccatcgtg tattggtctt ctctgaaaag cgactgccga atgatttctt ctgcagcact
    31381 cccaccaaat gaaagccagc aatacatcca cggatcttct ccatctgata agtaaaacgt
    31441 cgagtctcct ggacgaatca agaacagatc accttttttc aattggaatt gttgattttt
    31501 cacatgataa gatcctttgc cttccatcac gacatgcagg atgtaatcat tgcgaatagc
    31561 aggaccaaaa gaatgaaacg gcatcgtttt agagaaacca caaaaatcaa aatacaattc
    31621 tttttctact tgttgatgtt ccttttttaa aaaaatcgat tgctccacgt ctatccctcc
    31681 ttactccttt agtataatgc aacaaaaagt taaataaaag tcacagaaat atattaaaaa
    31741 ggaagcgatt tcttgttaag tttaagtcat taaaagatct ttgttattcg ttgtaaccgg
    31801 tttacttagt attatatatt gaacaggaga ggaatacaga ttatgaaaag caaaatgatc
    31861 caacgtgtgt cctacgcttt aggcgctttt ggacacgaca cattctatgt tacattaagc
    31921 acttatttta tggtattcgt gacaagccag atgttcgcag gaacagataa ggcaacgaat
    31981 gcaaaaatga ttgctacagt tacaagctta gttgtaggta tccgcttagt tgaaattatt
    32041 tttgatcctt tgattggtgg catcatcgat aatactcgta caaaatacgg taaattcaaa
    32101 ccatggttag ttatcggcgg cgttgttagt tccgtactct tggtagcaat ctttaccaat
    32161 ttctttggct tagctactca taatacgact ttatttatca tattatttgc aatcgttttc
    32221 atcttattgg atagttttta ttcatttaag gatatcgctt tttggtcaat gattccagct
    32281 ttgagtacgg aaacaaagga acgtgaaaaa tttgctacgt ttgctcgttt cggctcttct
    32341 ctaggtgcaa atggtactac tctagtcgtt gtccctatcg ttactttctt tacctatctt
    32401 gttactcata aacatattga aggcgcttca ggctggttct ggttcggtgt gattgctgct
    32461 gttatttcag gcggtactgc gattatcact gccttgggca caaaagaagt cgatactgcg
    32521 atccgtcagc aaaatgaaaa agctgggatc aaagatgtgt tcaaagcagt tgctcaaaat
    32581 gatcagttga tgtggcttgc ccttgcttat atcgcttatg cgattgccaa tgtagcaaca
    32641 actgccgtat tattctactt cttcaaatat gtacttggcc aaccaactga attttggatc
    32701 gttggtctag ttgctgcctt acttggttta gtagctgttc cactattccc aatgcttaca
    32761 cgcgtcatct ctcgtcgcta cgtttacctt ggagggatcg caatgatgat ttcttcttac
    32821 tttttcttta cgatcgcagg ttcaagtttg ccaatcgtta tcatcgggct agtattgttc
    32881 tacttccctc aacaattgat tttcttatcc gctttgatga cgatcacaga ctctgttgaa
    32941 tatggtcaat ggaaaaatgg tatccgtaac gaagctgtta ctctatcaat tcgcccttta
    33001 ctagataaaa tcgctggtgc tttgtctaac gggatcgtag ggtttgtcgc tatcgcttct
    33061 gggatgactg gtaatgctac tgctgctgat atcactgctc atggcgtaac gactttcaaa
    33121 gcttatgcat tctatgctcc tgctgctttg atgattttct ccgctattat ttttgcttgg
    33181 aagattacat tgacagagaa aaaacatgca caaatcgttg agaaattgga aaacaaattg
    33241 gctccagctg atacaatgga agatgaactt cacgatgcag tagttccttc ccattaagaa
    33301 aggatcttga aaatgaagat tacagaaaaa gattttggcc aaggttatca cttgataacc
    33361 ttggagaaca aaaacaagct agcactttct atctctgatt taggtgctag aatcgtcagt
    33421 ttaaaatcaa atgatcgaga attagttttg ggatttgaca ccgctgaaga atatatcgaa
    33481 aaagatccgt atatcggtgc ttctatcggt cgcaccgcag ggagaatcga aaatggccac
    33541 ttttctctca atggaaaaac ttaccaatta gccacagatc caaaaactgg acataatctg
    33601 catggtggtg ctcctggatt tgaattaaaa aaatggtctt atgtcatttt gaatggcgaa
    33661 aatgaagctt ctgtcatttt tactactaca agtcccgacg gagaacatgg ttttccaggt
    33721 acaatggatg tggaaatccg ctatactttg acaaaagata atatctggcg agtgacctct
    33781 cgcggcacca gtgaccaaga tactttattc aatccgacaa atcatgttta cttcaacttg
    33841 acgggagatg cttctcagtc aatcgatcaa catgagcttt ggctcaatag cgaagcttat
    33901 gctcctttgc gaacagatag tattcctata ggggtaaaag aaaatgctgc aggaagtgct
    33961 ttcgattttc aaatacctaa aaaattagcg tccgtttttg ctagtgattt ggatcaaaaa
    34021 aatcttgttg acggaatcga tcatccattt ttcttaaaag aaaccggctt gggtaaagaa
    34081 gccgctcgct tgactagccc cgataaaaga atccaagtag atattgctac agatgcttct
    34141 agtgtggtta ttttcactgc aaatttcggc acagaaacac cagaaatgcg caaccgaaaa
    34201 ctggcacatc acggtggcat cacatttgag actcaaacag ctccaggtgc agagcgcttc
    34261 tcagcatttg gttcgattca tttaaaagcc ggatcagtat ttgaaacagt gacagaattc
    34321 aaaatcaaaa caagaaagga ataactcatc atggaaatca aaagaagctt aaacacaaaa
    34381 tttgccgaaa cattcggacc taaaaaaact acacaatact tctcaccagg acgcatcaat
    34441 ttgattggtg aacacacaga ttacaatgga ggccatgtct tccccgcttc catcacttat
    34501 ggaacgcaag gtgtagcagc acctcgagac gataataaaa tattagttta ttccacaaac
    34561 tttgacgata tcggtgtcat tagttttact ttagatgagc tagaatatga taaaaaagca
    34621 aactgggcaa attacgtaaa aggaatggtc cttaaattaa aagaagctgg acactcaatc
    34681 gatcatgggt ttgagttatt agtggaagga acaatcccta atggtgcagg actttccagt
    34741 agcgcttcat tagaattatt agtaggtgtt gtattagaag atctgtttga tttaaaaaca
    34801 gatcgcttgg aactagtcca aacaggtaaa aaagtagaaa atgaattcat cggtgtcaat
    34861 tcaggtatca tggatcagtt tgccatcggc ttcggtgagc tagatcatgc aatcttatta
    34921 gatacaaata cgctgaaata cgaaatggtt ccagtgaaac tagatggtta tgcaatcgtc
    34981 atcatgaata cgaataagcg gcgggaattg gcagattcaa aatacaatga acgccgtagc
    35041 gaatgcgaag aagccttggc acgtttgcaa aaaactttgc ctatctcttc tttaggagac
    35101 ttagatgaag aagaatttga atcaactatt gaccaaatcg gcgatgatac attgatacgc
    35161 agagctcgcc atgccgtttc tgaaaatcag cggactttga aggcaaaagc tgaattagaa
    35221 gctgggaact tagaagcatt tggtcaactg ttaaatgatt ctcaccactc tcttcgctat
    35281 gattatgaag taactgggat cgaattagat acactagtag atgctgctca aaaacaagaa
    35341 ggtgtcttag gtgcacgaat gacaggagct ggatttggtg gctgtgcgat tgctcttgtc
    35401 aaagaagaaa atatacctgc cttcaaaaac aatgtctatg atgaatacat gaaagttgtc
    35461 ggctatgctc cggaatttta tgttgcacac attggaaatg ggacaacaaa gatcgatcca
    35521 gaagctgttc atgtttgata aaaaaatcaa cgatctcagc taaaaacaaa tagataaaaa
    35581 taacctctca gcaatttcca aatgtgagcc ttttgctcgt atttgaaaat tgctgttttt
    35641 tattgacacg gaaagagaac gtgtgttcta attgtgttga agaggtgatt gttatgtggg
    35701 cgaatcaaaa tccggtattt gtttatgaaa aagaaccttc aagagatatt ttatgtattg
    35761 actgcaaatc tttttacgcc tccgtagagt gcgttgaaaa ggatcttgat ccccttacaa
    35821 ctaaattagt agtcatgtcc tatccgtccg attcgacaga aacacggggt agcggattaa
    35881 tcttggcttc cagtcctgca gcaaaaaaag cttacggcat caccaatatc agccgtgcca
    35941 gagatcttcc cttcccctat ccaagtgatt tatatattgt tgccccaagg atggcctatt
    36001 atatggaaaa gaacagagaa atcaattcta tctataaaaa atatgcagac gaagcgaacc
    36061 atcatgtcta ttccgtcgat gaaagcttcc ttgatgtaac aaatagcatg gcactctttg
    36121 gtaaaacaaa tgcgtacgac atggctaaac tgatccataa agatgtgttt gagcagaccg
    36181 gaatctacac gactatagga attggcgata acccgctact tgctaaacta gccttagaca
    36241 atggctcaaa agacggaaag caaatgtttg ctgaatggcg ttatgaagat gtaccagaaa
    36301 agttatggaa aatctcagat atcactgact tttggggaat cggcaaacga acagcaaaac
    36361 gtctgaaaca aatgggtata cattctgttt atgatttagc tcacgcggat tattatcact
    36421 tgaaaagcaa gctaggggtc atcggtactc agctttatgc ccatgcttgg ggcatcgatc
    36481 gaagtttttt gggacaagaa tatacaccaa aatcaaaaag tatcggaaat agtcaaatcc
    36541 tagatagaga ttatacaaga cgagaagaaa tcgagatcgt tatcaaagaa atggccgacc
    36601 aagtcggcac tcgcttgaga cgatctgcag caaaaacaca agtagtcagc ttatgggtag
    36661 gatactcttt aggctatctt gatccaaatg gcaagaccgg gtttcaccag caaatgaaaa
    36721 tcgaagcgac aaatgctagc agagatctag cagatgcttt attgaccatt ttccaccagc
    36781 attaccacta ccaggatatt cggcgtgtag gcgtgaactg ttccgacctc gtatacgcga
    36841 caggtttaca gcttaacctt tttgaagatc ctgaaaagca gataaatgaa gcgaaagttg
    36901 attttgttgt cgatacgatt agaaaaaaat acggctttca atcaatcatc catgcgcata
    36961 gtctcttgca aggaggacgc gccatcgcac gtagttctct cgttggcggg catgcaggtg
    37021 gtatgagtgg attagaaggt ggaaaagatg agacggacag caaaaaaatt cattgactat
    37081 aacgagtatc gagatcggcc atttggatta aaatggggga ctgcttttgc gatggaagaa
    37141 ctagtcaacg gtatcaaaaa aaatgaagaa gaagcacgca aacagcctct tcctaaacaa
    37201 caaatgacat tgcaagaaat cgatagtata ctgacagaag cctttttatc tcgtaaagca
    37261 gtaatcattc agctcaattt aaaagatgaa tttggaagac tcttggatga ggtcgaaggg
    37321 cacttcattg gtgaagccta tgaagattac tttatgattg accatcagcc gatattgtgg
    37381 gaagacgtac ggtatattga gttaaaggaa acaaaaaaat ggtttgtgac atgagaggtt
    37441 gtgacagaag tgatcaactt caaaaaataa gaaaggattt ttcgaaaatt gcttcttaaa
    37501 tttttgtgga attttggctt atttttcgaa gaagcaactt ctggaacaac gtatattaga
    37561 tatcagaggt tgtgaaaaag tcgcttagtt ttgagtaaca agccaaggcg ctgatttcac
    37621 aacctctgtc tatctatcca tctattcggt aagattcatg catgacgtct tctttattta
    37681 gtatgtagag ccctttttct tctgaccatt caacataaat cagctgtttt acatctgcat
    37741 agccttcttt cttcaagttc tccataagcc atgcttcagt caattgattg gactgaagca
    37801 ctttatgctg aatttgccct tcatctacaa gcaggatcga taaagctttg tcttcatctg
    37861 attttttcaa tacactcatt tgaccggcat tctctaggat aacatgtttg gcattttcaa
    37921 gaaaaaagca ttcttgctgt cttaagattg ctcgcaactg ctccatctcg atatggttat
    37981 ttgtcaactc tgtcatgttg atgacgccgt ctttgattag aacagatggc tcgcctttga
    38041 cccaacgatt gaccttttca tttttttgga cgatacgttc gataccataa atcattactg
    38101 cccaaagcgc aatggcaaat aggacatgcc ctacatggac attgtcatca taggttgatt
    38161 cttctaagat cccacctaaa acaagcgtat agactaaatc aaacggtgtg atttctgaca
    38221 tggatttctt cccaagcaaa cgtaccacta ataataaacc gatcaacccg aacaccagtt
    38281 tcattgtaat tgaaaaaatc attttttctc cccctaacta tctgttaatt aaattatata
    38341 tgctttctca cgaacacgca tggaatatac aaggaagaaa tgtatccttt tactaaaaaa
    38401 aggactgtga cactgtagtg acccccaaaa gttagacttt tttggagtgg agaaatccac
    38461 tccttttttt tatgctctaa aatgatattt ttacacaacc gttacggttg ttttacgaaa
    38521 ttggacgaga ctttgccagt ttaatttctg ttttatccgt tcattattgt agtaatagat
    38581 atagctatcg atggctgatt ttaattcctc gaaacagtta taaactttcc cgtgaaaaat
    38641 ctcttgtttt aataagccaa aaaaattctc cataagtgaa ttatctaagc agttcccttt
    38701 ccgagacatg ctttgaaaga ttttgtactc cttcaatttg tttctataag ctttcatttg
    38761 atacgcccaa ccttgatctg agtgaaacgt acgacgatag ggacaatcgt tagtggtctg
    38821 gatagcttcc tccaaacctt ccattaccgc taatgcattg ggcttttcag agatacgata
    38881 ggataaaatc tcactattga acatatccat aaaaggatct agatacaatt tcttttgacg
    38941 gataatgcct ttggcatcca cttcatggta tttaaattca gttgtatccg tcgtgatttt
    39001 ctgatggcag atactggtgt agaaacgacg atggatccga tttttggcta ctgctccaac
    39061 ttttcctcga taagaattgt agcgacgtga tttacgcgtg tatgccgtta cttttattcc
    39121 tagcttcttg atcaagcgct gaactttctt tttattgata gagaaaccgc ggtttcttag
    39181 ttcattggtc atccgtaaac agccataatc cttgtgcttc tcccgaattt taagcatttc
    39241 cgcttcaatc tcttgatctg gatttttacg gtccaatcgc ctttgccatc caaataatca
    39301 tgaacgatct ttaatttaag ttcaaaagta tatttaacca taaaaaatac cgacctccaa
    39361 aagttagatt ttttggtcta acttttgggg gtcggtacac aaatcgtgtc acagtccctt
    39421 ttttgaaaat aaacggtgtt caaaagcttg catctgcggt aataagtcca gccaagttaa
    39481 aaacataaga agctgttttt acttggctgt tcttattact tgatgcaagg cagctttttc
    39541 acaacctctt ttcaaatatt tcgttttctt attctacaaa tggttcttct cctaacgctt
    39601 gttgagcggc tagattcaac atgctccatt gtcggtcaaa gcctggctgg aagaagaagt
    39661 cagcttctgc tagttcttct aaagtcagtt tgttttggat cgctagtgcc aatacatttc
    39721 cttgacctgt aacatcatag gtagataata ctgctcctcc tagcaattga tgggtcattg
    39781 gatccgagaa taattggatg gacacttttg gatttccttg ttcttctggt acatattttg
    39841 gtcgtaacgt atcttcataa taagacactc gtacatctac tcctgctttt gctgctgtaa
    39901 agctattcaa tccgcttgct gcaaaatgat agtcaaagac acttaatgca gaggaaccta
    39961 cgactccgcc gaacggtttg tttggtactt cttcaaaaag atgttttact acataacgtg
    40021 cttctctacg tgcaacagtc gctaaagcga tcggcatttt tttgcgtgct gggatagaat
    40081 aagcaagtgt agcatctcct actgcataca catctggaag attcgtttgc aagtattcat
    40141 ttgtttggat ccagccacgt tcatctaagt cgacgatccc ttttaaccat tctgtatttg
    40201 ccttcacacc ggcagcttga atgactagat ctgctgggat ttctttttca cttgttttga
    40261 ttgcctcaac ttttccgtta ccagtaaaag cttcgatttt tgcatttgtc aaaacttcaa
    40321 taccgttttc atttaggtgt tgttctaaaa tatctgtcat ctcagcatct aaataagtgc
    40381 ctaaaggtct atcgatcaca tcaagcaata cgacttcttt cccagctttt cggcttgctt
    40441 ctgctgcttc gatcccaatg taacccgcac ctacgacagc gattttttta atagccggat
    40501 catttaattt ttctttgatt ttggttgccc aattgtatcc acgcatcaag tagacatttt
    40561 ctagatctgc tcctggtact ggcagattgt ttggtttgac accagaactc aaaatcaatt
    40621 tgtcataagg atattctttt gtttcgttat ctgatgcgct agtaaccgtt actgtttttt
    40681 tatcggcatc gatcgttttt acttcgtgat tatttaaaat atgaacattg gattgcggaa
    40741 agttttctgg tctgaaatta cgtacatcat ttacatctgt taccttgtct tctaaataca
    40801 gctccatacc acatgacatg aaggaaatat agtctcctgc ttcaaatagc gtgatatcta
    40861 cattttcacc gtatcgtgtc aatagttcca agatcgattg atgccctcca tgagatgcac
    40921 ctacaatgac aactttgatt ttttccattg atgaaacctc cttgaatatt cttttaaaat
    40981 cattctaaac aatttaaact taacattaca ttagttatga atcaaaagaa acgcgttcat
    41041 ttgaactaaa tttaaaaaac aatcgtctcc ttgcagaata taccgcaaaa ttaacgattg
    41101 tttttttgat aaaatctatg aatcactgtt ctgttaaaaa gtctttgatc cgtttgcagg
    41161 cctcatgtaa tttttccatg ctgctagcat aagaaatccg gatataacct tctccttctg
    41221 ggccaaatgc aattcctggg atacacgcaa cttttgcctg ttccgctaat tctacacaaa
    41281 actgccaaga gtcagtttga atggcagctg ggagtttgca aaacaagtaa aatgcaccgt
    41341 ttggctgggt cacttcaaat cctaaaggcg ccaattgctg gaccagatag tctcttcgtg
    41401 tttgatattg ctctttcata ttctcgctat ctttcacccc atttattagc gcttcagccg
    41461 cagctttttg cgacatcgtt gtagcggcag tcaccagata ttgatggact ttaattagtt
    41521 cgtcaataag ggctttttga gcaaaaataa agcccactcg ccaaccagtc atcgcatgtg
    41581 acttggataa cccgcttatc acgattgttt gttctggaag ataagtagct atggacatat
    41641 gcgttccact ataagtcaat tcagcatata cttcatcact tataacaaat accggatatt
    41701 tttttaaaac ctcagcgatt gctttcaatt gttttgcaga caatgtcgtc ccagtaggat
    41761 tgttaggata gtttaaaatg actgctttga cagctgatcc atattgttca aatgctcgtt
    41821 caaattgttc cggctgacag acaaaccctg tgtcagaagt atctatcggg atcaattcag
    41881 caccagctag ttccactaat ggctgatatc ctgaataagc aggcgctgga ataagaacct
    41941 tgtctccttc ttccaaaaca gataacaacg cagaggcaat cgcttccgtt gcaccaactg
    42001 tcgtcaaaac ttccgtttgc ggatcataag ttaatccata acgctgttgc tgaaatatac
    42061 aagccgcttc ccgcagttcc tctaatcctc tcattccggt atagtgagaa aagtcttctt
    42121 caatcgctgc tattcctgct tgcttgacat gttcaggagt tggaaaatcc ggttctccca
    42181 gggtgagttt gatcacatct ggtatcgacg atatttgctg atcgaattgt cgtatttttg
    42241 atacttctat tctagaaagc ctaggactaa atcgattgga taaattcatc attatttact
    42301 cgctcctctt ttgaactgct atcgattttt acaagaagat tttctgtaaa aagaatcgtt
    42361 ttgtaccatt ctacaccatt ttctaaaaca tccatatcaa aatcgaacgt cggatcatgt
    42421 aaagcagggg tatcaccgac acctaaaaag aaaaatacac atggatattg ttgcgtatat
    42481 atgccaaaat cttcggcttg aagaactgga gcatctaatt catgtagttt gtttgaatct
    42541 aacagtgctg catataagcc tctatggttg attacagctg gatagccgtc attatagcga
    42601 aaagaaatag tagctgtaga gtgaaactgt tctgctaaat ggtctaatcc cctcttcaaa
    42661 taattttgca tatctgaact gtaagaacgg atacttccgg atacaataac ttctccagct
    42721 aaaacatttc ggatcgttcc accttggatt tggccaaatt tcattagatg attccactct
    42781 gccggtaatt gccggtcaaa atcataaaca ttcttcaaaa atcgtacagc tgcctccaga
    42841 ctatcgattc ctttttcact agaagcaata tgtgcagact ggcctttaat gataatgtct
    42901 gtttcactgc tttgtgccat caaaggtcct ggtcgagaga aaacttctcc cttagctagt
    42961 ccaggccata gatgaaagcc aaatattgct tgtacttcat atttatccaa caatcctgac
    43021 tgaataacgc tttgtgcgcc accggaaatt tcttctgatg gctgatagat cagtactaca
    43081 ttataaataa gatcctcaat gtgtttagtt ataaagtcag tcaaccctaa aagcatcgcc
    43141 atatgtccgt catgaccaca tgcatgcata taaccttcat gcttagaagc aaaagagaga
    43201 ttcgtttctt ctttgactgg cagtgcatcg atatctgttc gaaaagcaat cgtttcttct
    43261 tgctgattat caaaataaag gagtagtcct gtttcgccga tttcatggat aacggcctcg
    43321 ctgtttttta cttgttcata taaatatttt tttgtcttga attcatgaaa cccgatttca
    43381 ggaatttgat ggagtgccat tcgatattct ttcagcatcc gtattcacca tcccttcata
    43441 gatacccttc actactgttt catattgatt attcggtaca ccgatgatca gattcaactc
    43501 ctgtgctcct tgtgataaga tcgatgtgcg aatttctaat ttgttcaata tcgataacac
    43561 tttcccagat aatccaatca attctttatg cggaccccca acgacagaga tcaaagctaa
    43621 gtcttcgatc acgacgattt cttccacgcc aagtgtttct tttaattctt tcgtgatgag
    43681 aaataactta tcggcaatcg cttctgctga gacgatcact ccgatattgt cgatccctga
    43741 aggaatatgt tcgattgata tctcatgttt agcaaaaatg ctcattgctt tccagataaa
    43801 cccgatttca tcggacatat gacgtttgaa taaagtgatg gaaagaaaat ccttgcgtcc
    43861 agctattcct gtcagtccat tttccttttc tatttcgtga ttcgatattt ttgtcccttg
    43921 agcgaaagga tcattggtat tttttatttg gatggggata tcagcctctt gaactgggaa
    43981 aacagctgct tcatgaagaa cgttagcccc catataagcc atctctctca gttctctaaa
    44041 agagatttcc tcgatgattt taggatgatc gatgattcgc ggatcagcca tcatgattcc
    44101 tgaaacatcc gtccaattct cataactttc cgcttgcaac atcttcgcca gtatcgcgcc
    44161 ggtaatgtcg cttcccccac ggcccaataa tttttctttt cctgcagggt tcgccccgta
    44221 aaaccctgga acaaccattt tcggatatct tttaaatgct tttgtgattt cctgtgctgt
    44281 tttttcctga tcgattttcc catcatagtc aaagaaaatc aggtcttttg cgtcaataaa
    44341 ctggtaacca agatactcag ccatcagttg agcagtcaga tattcacctc tacttactaa
    44401 ataatcttca gttatctttt cgtcttccag ttgtttctgt atgcgtgcta gttcatcttc
    44461 aataggtaac tgcagggcaa gaacatctct tacttgaatg aaacgatcac aaatcctttt
    44521 ccaaaggggt gtccaatcaa catgatgctg aaggtaagca taaatcaaat aaagtaagtc
    44581 tgttactttg tcatcatctg acgtacgttt gcctaaagca gaaacaacga tcacttggcg
    44641 attgggatct gaaagaacaa ttgtacggac ttttttgaat tgctcttcat gagacatcga
    44701 tgttccgccg aatttcgcta ctttcagcgt attactcatc ttgccacctc cgctattttc
    44761 tgcattaaag ctgcagcaat ctgtacggca ttcgcagcgg ctcctttgcg tatgttatcg
    44821 gcagtcgtat agaacaacaa tccgttctct aaagaagtgt cttttctgat cctcccaaca
    44881 taaaccatat ctgttcctct agcaagaatg ctcgtcggat atttatgtgc tgctagatca
    44941 tcttctaatt gaatccctgg aaactggctg agacactctc taatttcttc cgtcgtaaac
    45001 tctttttgca gttgaactgc cacagagact ccatgtccat tttcgattgg cacacgtacg
    45061 caggttgctg atactggcaa agcaggctga tgcagaatct tacgggtctc atttatcatt
    45121 ttctgttctt cttttgtata cccattttcc aaaggctgat cgatttccgg aatcaccgtt
    45181 tggctaatat tataaggata caaaactggt tcctcgtcat tttgcgtacg atgaagatct
    45241 tcaatgcctt tttgcccgga accagaaact gcttgatagg tcgaataatt gactcgctgg
    45301 ataccaaagg cttcttgtaa agctttaagc ggaagtaccg cttgaatggt tgaacaattt
    45361 ggatttgcaa tcagccgatt caatgtatag tcttccagat tgacctctgg aacgattaat
    45421 ggaatatccg aatcttcccg ccatgctgag gaattatcta tgacaaatag tccctgactt
    45481 cgtgcgattg gcgcaaactc tttggataca gaagcacctg cagaaaatag cgctaaatca
    45541 tatccttcaa atgaagtttc tgtcaattcc tgtacagtgt gtttcttttt cttgaataca
    45601 caaactttac cggctgaacg ttttgaagct aataatttca atcgtcctac tggaaaatca
    45661 tattcttcta acactttgag catcgtttgg ccgactaatc cggttgcccc cacaatacag
    45721 gtatctattt cgcgcatttt tctccatctc ctctataatt cgcgtaacgc agcaatcaat
    45781 gctgtatttt cttttgtctg atcatcactt atttttaata cacgtgcagg tattccaccg
    45841 acaacagttt ctgctgccac atcttctaaa accactgctc ctgctgccac gactgcatct
    45901 tttccgatat ggacaccttc aacaatcact gcattcgcac ctaccagtac gccgtcttct
    45961 acgataaccg gtttggccga tgctggttcg atcacacctg ctaagacagc tcctgcacca
    46021 atatggcagt ttttgcccac tgtcgctcgt ccacctaaga cagcacccat atcaatcatc
    46081 gtgttttcac cgattactgc accaatattg ataatcgctc ccatcatgat cacggcattg
    46141 ttgccgattg acacttgatc tctgataata gcacctggtt cgatacgagc attaattttt
    46201 ttaatatcta gcaaaggaac tgcgctgtat cttgcagcag tttcgatttc gatttcaatg
    46261 attttttctg attcagcttc taaaaccgga gcaatcgtct catagtcacc aaaaacaacg
    46321 aagctgcttc cttcaccaaa aactttactt tctttaaatt cgattggctc ggttacattc
    46381 agatagactt tcacaggcgt ctttttagat gccgtttgaa tgtagcggat gatttcttga
    46441 gcttccacgt tttttacacc cctttgtcca ttaataaatc ttctaatttg taataacctg
    46501 gtgactgatc tttcaaccag tccgctgctt ctactgcgcc tgcagcaaag attcgattag
    46561 aaaaagattc atgtttgatc gtaaatattt catcagtagc agcaaacaat acatcatgtt
    46621 caccaggtaa agaacctgca cgaatactgt gtacaccaat ttggttttct tctctttttt
    46681 tcccttgcca gttgtatacg ggctgcagct tttgcacttc ttggattgtt tgaagcagca
    46741 tatttgcagt accagatggt gcatcttttt tacgactatg atgtttttca atcagttcga
    46801 tctgccagcc ttgcaacatt gcagctgctt gcttgattag ttgattcatc accatgatgc
    46861 cgaacgaaaa attagcacta tacatcacag gtacatgttt ggcatgttct tttatttctt
    46921 ggaactgtga ttgtgtataa cctgtcgtgc caatgactaa cggaagttga tatgataagc
    46981 tatacgaaag gattttctct aaattatctg gatgagaaaa atcaataagc agttctggca
    47041 gttccgtaaa agcaagcgta gttgcttctt taggtgccgt ccgtaaaaga aggaccgtat
    47101 ctcctctttc ttgtgcaact tcttcgactc tatttcccat ctgtccactg ccaatcagtc
    47161 cgattttcat ttttcaaccg tcctttcttt taacaaaagc tgagctaatt gtttcttttt
    47221 ctcttttgaa agagaaacta aaggcaggcg tagaggtccg gaaggtaagt ctaataatga
    47281 catggctgct ttgacaggaa taggattggt ctcactgaac aaggcatgga tcagttcaag
    47341 tgcatttaat tgcttttctt ttgcttgctg ccatcttccg tcctgcgtat cttttactaa
    47401 ttcatggact attttaggtt ggatattcgc ccatacactt attacaccgc ttcctcctac
    47461 actcattact ggtaggatca aatcatcatt tccactgtaa aggaagaatt cttctccaat
    47521 caaccgagcg gcatccatca cataagccat atctcctgag gcttctttca aaccaatgat
    47581 attaggatgt tctgctaaat ttactaatac atggattgga atcgacatgc ctgttctaga
    47641 aggaacatta tacaaaataa gcggaatcgg tgaggcttct gcaattgctg taaaatgagc
    47701 agctagtcct gcatcacttg ttttgttgta gtaaggggtg atgaccaaaa gtgcgtctgc
    47761 ccccaaagaa gcaaaatgct tcgctttttc aatcgtttct ttcgtattat tcgttccagc
    47821 tcctgcaatc accggcacac ggccagccac tttctttact gtcagttgaa ggatctgctc
    47881 ctcctcagat tgtgtgagcg tagaagattc tcctgttgta cctaaaacta ataatccatc
    47941 tgtttgttca tctaaatgga attggatcaa tttttccaaa ccagcataat ctactgatcc
    48001 ctcttcattc atcggcgtga tcagcgccac gatcgaacct tttatcatct tcattcctcc
    48061 aatattcttg tccattcatg aactgctggg ccagccattt gtatcgcatc ctcaccagag
    48121 atcatcaagt ctccttgttc caagtgaaca actacctgat ctgctgaaat tttcccagtt
    48181 tccttagcaa ccacataaga ggcacagcaa cctgtaccgc aagcaagtgt ccaacctact
    48241 cctctttcat aggtacggac gatcaattct tgttcattga ctacttctac aaagttgaca
    48301 ttggtttttt ctttgaacaa aggatgatga cagatcagtt cacctctttt tctccagact
    48361 tcctcacgcg cattttcaac aaaaacaacg gtatgaatcg ttcctaaaaa taaactagtg
    48421 atcgttactt tttcaccatt gatctctatt tcctggtttt ttattggata agtttgatta
    48481 gctttgattt tttccggaga atcatctggc actcccatat ctacgctgca ataaaaaggt
    48541 gagggatcca acaccgtaat ttttcttgtg cctgctaatg tctctacgtt gaattcctgt
    48601 tcattcatca tgttctgatc atttacgtat cgagcaaaac agcgaatgcc atttccgcac
    48661 atcggcgcgc ggctgccatc tttgttgtaa tagatcattt ccaacggatc gatttttacg
    48721 gcgatcaatc cgtctatatc atatttttct tttgtgcata aagaagcggc taattgacta
    48781 taatctgtgt cttctgcgta atctaataag ataaaatcat ttccgcagcc attatattta
    48841 tgaaggatca taggaaactt ccccccttag tagatcagaa aatgcttgtc tgcgaacaat
    48901 cagtcttgat tggccattat tgacaaaaac aactgctggt cgtgtcgctc gattgtagtt
    48961 gctgctcatc gagtatccat aagctcccgt ggaataaaca gctaaaagat cacccgattc
    49021 tgctttcggc aaataagctt ctttaattac cacatcgcct gattcacaca tttttcctgc
    49081 aatcgtcact ttctctgttt tttcttccga cagttttgct gctaaatcac aatcgtattc
    49141 tgcctgatac agagctggac ggatattatc tgtcatcccg ccatctacaa agtaatattt
    49201 tttatgtggt gtctttttga tgaaaccaat cgtgtatagt gttgtaccag cttctccaac
    49261 aatacttcta cccggttcga tcagtaattg acgaatggtc agttttcgtt tttccaaagc
    49321 ttcttccgta tattcaatca gtttttttag tgcctcttcg actgggatcg gctgatcatt
    49381 ttgtgtataa cgaatcccaa accctccgcc aagattcaag gaaagaggtt ggtcaaaatc
    49441 ggttaagtaa ttcgtcaatt tgtcgatttc agctaaccaa gcagtaacat caaaaatttg
    49501 tgacccgata tgagcatgaa atccttctaa ctctagatag ctgctttctt ttatcaactg
    49561 aagggcttgt tggcactctt tactttcata gctcatgccg aattttgaat caatatgcgc
    49621 agtgacgata tattcatgag tatgtgcttc tactccgaca ttcaaccgaa gcatgataca
    49681 aatttttttt aaatagcgtt ggcttaattc tgctaataat tcaacttcca tcaaattatc
    49741 ggcaacaata tgcaacaaat cattttcaag tgcatagatc agttcctctg gcgtcttgtt
    49801 gttaccatgg aagtagatag tatctctagg aaaatcagct tgcaaagcgg tatagatttc
    49861 cccaccactg acaacatcta gcccgaatcc atattcacga actaaatgca gcatctcaat
    49921 cgtttggaat gctttagagg cgtaaagcac ttttgtatca aaacgtttcg atacaaagcc
    49981 tcgcttgaat gacagcatcg tttgtctcat cttttcttca tcatacacat acagaggtgt
    50041 cttatacttt tctgccaatg tgcttgctgt gactccgcca attatcaatt ctgtcatttt
    50101 ttcattcctc ttttcacttt ttttccgttt ttattggaat ttcatttgat aaagatttga
    50161 attttattgg aataatatta aacaaa
//
LOCUS       DACDAF010000011        45749 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.011, whole genome shotgun sequence.
ACCESSION   DACDAF010000011 DACDAF010000000
VERSION     DACDAF010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 45749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.011"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            101..544
                     /locus_tag="IVZ69_000581"
     CDS             101..544
                     /locus_tag="IVZ69_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP8182695.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(550..1734)
                     /locus_tag="IVZ69_000582"
     CDS             complement(550..1734)
                     /locus_tag="IVZ69_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HAP8182696.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            2002..2700
                     /locus_tag="IVZ69_000583"
     CDS             2002..2700
                     /locus_tag="IVZ69_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HAP8182697.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2707..3384
                     /gene="nth"
                     /locus_tag="IVZ69_000584"
     CDS             2707..3384
                     /gene="nth"
                     /locus_tag="IVZ69_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HAP8182698.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(3510..4043)
                     /locus_tag="IVZ69_000585"
     CDS             complement(3510..4043)
                     /locus_tag="IVZ69_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182699.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(4340..6721)
                     /locus_tag="IVZ69_000586"
     CDS             complement(4340..6721)
                     /locus_tag="IVZ69_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HAP8182700.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(6711..7358)
                     /gene="recU"
                     /locus_tag="IVZ69_000587"
     CDS             complement(6711..7358)
                     /gene="recU"
                     /locus_tag="IVZ69_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HAP8182701.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            7422..7961
                     /locus_tag="IVZ69_000588"
     CDS             7422..7961
                     /locus_tag="IVZ69_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HAP8182702.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            8051..8470
                     /gene="gpsB"
                     /locus_tag="IVZ69_000589"
     CDS             8051..8470
                     /gene="gpsB"
                     /locus_tag="IVZ69_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HAP8182703.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            8492..8859
                     /gene="rnpB"
                     /locus_tag="IVZ69_000590"
     ncRNA           8492..8859
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IVZ69_000590"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9068..10234
                     /locus_tag="IVZ69_000591"
     CDS             9068..10234
                     /locus_tag="IVZ69_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HAP8182704.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            10280..11776
                     /locus_tag="IVZ69_000592"
     CDS             10280..11776
                     /locus_tag="IVZ69_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HAP8182705.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            11857..12540
                     /locus_tag="IVZ69_000593"
     CDS             11857..12540
                     /locus_tag="IVZ69_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP8182706.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            13185..14375
                     /locus_tag="IVZ69_000594"
     CDS             13185..14375
                     /locus_tag="IVZ69_000594"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HAP8182707.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            14477..15430
                     /locus_tag="IVZ69_000595"
     CDS             14477..15430
                     /locus_tag="IVZ69_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HAP8182708.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            15499..16848
                     /locus_tag="IVZ69_000596"
     CDS             15499..16848
                     /locus_tag="IVZ69_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8182709.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVIAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(17031..17354)
                     /locus_tag="IVZ69_000597"
     CDS             complement(17031..17354)
                     /locus_tag="IVZ69_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182710.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            17483..18646
                     /locus_tag="IVZ69_000598"
     CDS             17483..18646
                     /locus_tag="IVZ69_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182711.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            18716..20065
                     /locus_tag="IVZ69_000599"
     CDS             18716..20065
                     /locus_tag="IVZ69_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP8182712.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(20110..20541)
                     /locus_tag="IVZ69_000600"
     CDS             complement(20110..20541)
                     /locus_tag="IVZ69_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8182713.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            20929..23571
                     /gene="alaS"
                     /locus_tag="IVZ69_000601"
     CDS             20929..23571
                     /gene="alaS"
                     /locus_tag="IVZ69_000601"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HAP8182714.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            23771..24367
                     /locus_tag="IVZ69_000602"
     CDS             23771..24367
                     /locus_tag="IVZ69_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP8182715.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            24489..25637
                     /locus_tag="IVZ69_000603"
     CDS             24489..25637
                     /locus_tag="IVZ69_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP8182716.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(25675..26088)
                     /locus_tag="IVZ69_000604"
     CDS             complement(25675..26088)
                     /locus_tag="IVZ69_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HAP8182717.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            26167..26598
                     /locus_tag="IVZ69_000605"
     CDS             26167..26598
                     /locus_tag="IVZ69_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HAP8182718.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(26697..26930)
                     /locus_tag="IVZ69_000606"
     CDS             complement(26697..26930)
                     /locus_tag="IVZ69_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HAP8182719.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            27113..28783
                     /locus_tag="IVZ69_000607"
     CDS             27113..28783
                     /locus_tag="IVZ69_000607"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HAP8182720.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            28930..29316
                     /locus_tag="IVZ69_000608"
     CDS             28930..29316
                     /locus_tag="IVZ69_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182721.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            29303..30001
                     /locus_tag="IVZ69_000609"
     CDS             29303..30001
                     /locus_tag="IVZ69_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP8182722.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            30006..30470
                     /locus_tag="IVZ69_000610"
     CDS             30006..30470
                     /locus_tag="IVZ69_000610"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HAP8182723.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            30467..31378
                     /locus_tag="IVZ69_000611"
     CDS             30467..31378
                     /locus_tag="IVZ69_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP8182724.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            31613..32152
                     /gene="pyrR"
                     /locus_tag="IVZ69_000612"
     CDS             31613..32152
                     /gene="pyrR"
                     /locus_tag="IVZ69_000612"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015694870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HAP8182725.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            32166..33449
                     /locus_tag="IVZ69_000613"
     CDS             32166..33449
                     /locus_tag="IVZ69_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HAP8182726.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            33462..34388
                     /locus_tag="IVZ69_000614"
     CDS             33462..34388
                     /locus_tag="IVZ69_000614"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HAP8182727.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            34407..35687
                     /locus_tag="IVZ69_000615"
     CDS             34407..35687
                     /locus_tag="IVZ69_000615"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HAP8182728.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            35692..36768
                     /gene="carA"
                     /locus_tag="IVZ69_000616"
     CDS             35692..36768
                     /gene="carA"
                     /locus_tag="IVZ69_000616"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HAP8182729.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            36773..39958
                     /gene="carB"
                     /locus_tag="IVZ69_000617"
     CDS             36773..39958
                     /gene="carB"
                     /locus_tag="IVZ69_000617"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HAP8182730.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            40012..40788
                     /locus_tag="IVZ69_000618"
     CDS             40012..40788
                     /locus_tag="IVZ69_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HAP8182731.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            40785..41717
                     /locus_tag="IVZ69_000619"
     CDS             40785..41717
                     /locus_tag="IVZ69_000619"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HAP8182732.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            41714..42430
                     /gene="pyrF"
                     /locus_tag="IVZ69_000620"
     CDS             41714..42430
                     /gene="pyrF"
                     /locus_tag="IVZ69_000620"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HAP8182733.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            42437..43066
                     /locus_tag="IVZ69_000621"
     CDS             42437..43066
                     /locus_tag="IVZ69_000621"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HAP8182734.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            43054..43368
                     /locus_tag="IVZ69_000622"
     CDS             43054..43368
                     /locus_tag="IVZ69_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182735.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            43406..44047
                     /locus_tag="IVZ69_000623"
     CDS             43406..44047
                     /locus_tag="IVZ69_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP8182736.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            44078..44782
                     /locus_tag="IVZ69_000624"
     CDS             44078..44782
                     /locus_tag="IVZ69_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HAP8182737.1"
                     /translation="MKKNMDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKG
                     EETKIEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSE
                     HIINGKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVN
                     PDVFFPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPI
                     QPLNGREIYYFEEFEQ"
     gene            44779..45681
                     /locus_tag="IVZ69_000625"
     CDS             44779..45681
                     /locus_tag="IVZ69_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP8182738.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
BASE COUNT        15005 a         7997 c         9883 g        12864 t
ORIGIN      
        1 tttttcttgg tttcagattg ggttttccta caaaatattt ttatctttgt tgaataggaa
       61 acaaaaaaac aatataatga aagaaaaaga aggtgtagaa atggataaaa gacaactgct
      121 aatagaagaa tatctggatt tagctaatga gattattcat cgtaataaac cagaaatgga
      181 aaaagaattt gcaggattta ctctaaatga actagaagtg attgaacata tcgggaaaat
      241 ccctgatcct aacgtgacaa aattagcgaa tgctagttac atgactagag gagccatcag
      301 taagctaaca aaaaaactga tagctagagg gatcataaac acttatcaaa gcgaagagaa
      361 taaaaaagaa atctattttc aattgacgcc aatcggacaa aaaataagga atagacacga
      421 gcaactccat caaaaatggg tacagcgaga tgctactgta tttgaaaata tgtcaaaaga
      481 agaatttgac acagtatttc gttttatcgg tcgatacaga gaatttatac gaagtagcaa
      541 atgaagctac tattttttat tgtagtgata ataggcaaaa atcataagca aaaatccgaa
      601 taccgtcgga agaaatggtg ctgcagcata aagctgtcct gcgattagcg ggccgatgac
      661 gcgcgataga gattgtatac tttgggtacc gcccattaca agaccttgct ggttatctga
      721 gacagaattg gatagttggc cattgaatac aggagtaaaa atagaatcac cgaaaccata
      781 acagataatc ccaaataaaa acaaaatcgg cagtagaaga attccagata atgtgatgaa
      841 tagataggcg aggatttcac tgaacatccc tattcttgtg atctgctgtt ctgaaaattt
      901 tttgagcaat cgaggcataa tgaacaattg cgagacagta tccaagattc caatcaaaga
      961 gaagcttaaa ccaaccaacc cagccttcca ctgaaaggcg tcaatcgaaa attgagaaaa
     1021 gatagattga agagagccag ctgccaacca aacagcaaaa cctgctgtca ataaaggaat
     1081 aacggatgaa atcttgaata attgttgtaa ttggtgaaaa ggtcttacat gggagaaact
     1141 taaatctact gaacgttttt ttattggaag gctttctagc ataaatgtgt agccataaac
     1201 ggcatttaag aaagtaaaga gtgctccaat aaatatagga acagaattcc ccaactcagc
     1261 taatagaccc cctataatag gacccagcgt tgttcctata ccgactaaag cacccatcca
     1321 tccaaaaact ttggttcttt cattaggttc cgtgatgtcg gcaaagtaag catataaggt
     1381 ggagatttct cctgccgtca atccttcaat gatacgacca aggaacaaca tccatatcga
     1441 atttcctaaa ccaaaaagca aatatccgat acttgatcct aataaactga taataaggat
     1501 cggatgacgc ccaaaatgat cacttaagct accgagaatg ggggcagata agaaggcagc
     1561 tagagcataa acagacatga gcaaagtgat atagaaagct tgctgatgta tggagtgaga
     1621 ataaggcagc gttaaaaacg gaagtacagg actgacgata gtaaatccta atccagtgaa
     1681 taagacagag acgtatccaa aaactttaga atgtttattt gtgaaactgt acatgtaaaa
     1741 actcctttat gcaataatgt taacttggaa acaaaaatag tgtatagtaa ttttgtttcc
     1801 ttgtcaacat tctaaggaac agcgaaatct acttaattta tttattccga aaagtgaaga
     1861 tacgcatcaa aaacatgaac aaacaaaaat caagtagacg acattgtaaa tctgaccgat
     1921 cagtgaagta aatagaaaag aaacctgttc ttgcttccca tgtttttttt acgtatactg
     1981 tgattgagcg gaggagaaat catgttgaat ttagaaaatt acttaagcgc tggacaaaca
     2041 gtcatatcta atcttttact taaaaattat cataggatcg gtctacaatc tgaagaattt
     2101 ttatttgttc tacagttgca tatggcacag cttgaaggag atactttccc tgatttgcag
     2161 atgattgcta tggatatggg aatcaaacaa gatcagattt ttcaaatact ggatcgtctc
     2221 gtaacaaatg gatttatcaa gatagaaacg acgattgtca acggtaaaaa agcagatcga
     2281 tataatcttt accccatcta tgatctatta ggtgagtatt taaaaacaca agaaaaaaaa
     2341 tacgaagaaa aaacacaaga aaaagaaatc cagtcagtgt atcaattatt tgaacaagaa
     2401 tttggacgcc cgctttcttc gatcgagttc cagcggatcg gacaatggct agaagaagac
     2461 cattatcagc cggaaatttt gaagctagca ctgcgggaag ccgtattaaa tcaggcttat
     2521 agttttaatt acgttgaccg cattttgcta tcgtgggaaa gaaaaaatct acgtacaaaa
     2581 caacaagtgg aagaagacca aaaacgaaga aaacagcagc ttcttcaaag agaagtagaa
     2641 cagtcagctc aacaagaaga attgccgaaa gtctcactga aaaattggtt ggaggagtag
     2701 cggaatatgt taagcaaaca aaaaacaatg gaagctctag aaacgatgta tggaatgttt
     2761 cccgaagcac atggagaact caagcacaat aatccatttg agttattgat tgcagtgatc
     2821 ttaagtgccc aggcgacaga tgtatcagtg aataaagcaa cgccagattt gtttgcctct
     2881 tttccgacac ccgatgcgtt agcagaagct tcaatcgatg aaatcattct taaaataaaa
     2941 acgattggtt tgtatcgaaa taaagcaaaa aacatcaaag cgtgtgcaca gcagctgatt
     3001 gaacgtttcg atgggcaagt gccaacgtca agagaagaat tgatgtctct tcctggtgta
     3061 ggcagaaaga cagcaaatgt cgtattgggg gatgcattcg ggataccagc aatcgcagta
     3121 gatacccacg tggaacgtgt ctcaaaacgc ctgaggatct gcaaactaga tgctacggtc
     3181 atggaagtag aagaaacact gatgcggaaa gtaccacaag aattatgggt aaagacacat
     3241 catacactga ttttttttgg tagatatcat tgcacggcaa gaaatcccaa gtgcgaggta
     3301 tgtcctttgc tatcaatatg tcaagatggg aaaaatcgga tgcgtctaaa agaaaaggcg
     3361 ctaaaaaaga aaccacgcct gtagacgtgg tttctttaat tgcaaataaa tgtatgaatt
     3421 atcttgttat tatggagaaa agctgtttcg tttatctttt ttgcatgaaa aagtaaatgt
     3481 acatactcag tagctaggat ggtaacttat tacaatttat tgcgataaaa ataaaagttg
     3541 ttatttttat tgggaaaata cccgatgtag aaaataatgc cttccaatat acctataaaa
     3601 taagtccagt attccaaagg attatataaa taagtgacgt atctatctaa aggtgtaata
     3661 aaaatgataa gtgataataa aaaaatacca tttataacta aacataaact aatggatttg
     3721 ggcggtttca ggctcatcag aaaaatatag attctggtga acaacaacca taaaaaagtg
     3781 agaatcattg catgagagct tctttccata aattttcctt taagagtagt gcttaaaagt
     3841 acagaaaaaa taataaatgc aaggatagga gcaattaaag taaatttatt taataataaa
     3901 caaaattttt cagctttttt attcttggaa taacgaggta ttgttttcga taaaaaaaga
     3961 tggtgcagac aaattatgat aattaagcat actatcagat aactcaaaat gaagccttct
     4021 ttcaaaaaat tattcaaaac catatattgt attttttatt tgataataac aatgggatta
     4081 ttaagaagtg gcactaaata aaagactagt gtgtatttag ccgatttaat tataaacaag
     4141 taaatggata aagtatatgt aatgataaaa gaaaaatgga ttttctaatt tttaagctaa
     4201 atgttagatc acacatgtat atgctggata gtcttataaa aaatcatgta atacagcttg
     4261 gtacatgatt tttatttgta gctgtttttt acatagacac aaaaaagaaa ccacgcttgt
     4321 agacgtggtt tcttttttac tatctgtttc cagaagctga ggtgctgctg gatggtgtat
     4381 ggtcatttgc agcatccgct ccgctagttg ctggctcact ggaagaagca ggaggagcag
     4441 atgaagacgg tgtcgagctt tcttcggatg aagaagaagg aaccgttgtt gaagacgctg
     4501 gctcgcttgt ttctgctgtc gtgctttctt ttgaggactc agcagttgat tcgctttgac
     4561 tagtagagct agagctttga gtcgttgtct ctgttgttga gcttccagga gtctggacat
     4621 agctggaaga tggaatagtt gttgatggtg taattgcatt cgatctagct gtatattgat
     4681 ctttgtagta cagttcaccg cccacacgaa ttaatccgct tggcatctcc cagtctgtat
     4741 ttgtcacgtt agctgaaaca tactgcataa gctcgcgata aacatcagag gctacgtgtg
     4801 acgattctga agtgacaggt gtcatttttt tattgtaacc tgtccacacg gaaatcgaat
     4861 aatttggcgt atagcccgca aataggatat ctggatacac cccagaagaa ataccaagtt
     4921 ttgcatactc gtcatctgtg taattggatg ttccggtctt accggcttga tataacccag
     4981 cgatttgcgc attcgtacca gttccttcag tgatcgtatc ttttaaaatg tctgtgatca
     5041 tataagctgt ttctggagac atggctgttt ttccatctgg ctcataagtt tcttctgttc
     5101 cgtcttggaa gacgatttta ttaacatatt gaggtttgta ataagtccct ccattggcga
     5161 aagccgcata ggctgctgcc atttttaagg aagaagctcc gtattttgtc ccatcttgtt
     5221 cttccgtatt actagagatc gcattcgatt gatggatcgt actgtattcg atcccaagat
     5281 tttttaagaa agaagccact ttatctgaac cgacttcatt gaataatttg actgctggaa
     5341 cattacggga taagtaaagt gcttggcgta aagtaatggt gcccatatat tgattatccc
     5401 agtttcctac aggagtcgaa gtcccttcat agttatacgg tgcgtcagta atagtttttc
     5461 cagtagaata tttcaaatat tcaaaagctg gtccgtaatc tgtgacaggt ttcatcgtag
     5521 aaccaaaatc acgggaagta ttcactgcta agttgttgcc taaagttacg tcttctgcga
     5581 tgtgacgtcc gccaatctgg gcttttactt tcccggtatt ggtgtcgata agggtggagg
     5641 caacttgcat ctcgtcgtct gggtaagaga catactgatc cgtgttgacg atatcatata
     5701 gtttcttttg ggcgtccaga tccaaattcg tataaatctc taaaccgtct gtgtagacat
     5761 tcttatctgt tttttcttgt acttcattga tgacttcttt gacataatta tcgacgatct
     5821 tagtattgtc atcggattga gttagttctt gcagaccatc cgttaccggt acattaacag
     5881 cttgatcata ttctgtttga gagatttttt cgttttgaag catcgtatac aaaacagtat
     5941 ctcgtctttt cttcgcctga tctggataaa cataaggatc ataggcggaa ggggcttgag
     6001 gcatcccagc aagcaatgct gtttgcggta aagaaagttc tgataatttc ttaccaaagt
     6061 acatctcaga agctgtctcc atcccgtaca agccgtttga catatacact ttatttacgt
     6121 agtaggtcaa gatctcttgt ttcgattttt tttgttccaa tcttacagcc atccacgctt
     6181 cttgggcctt gcgtttcaga gtctgatcct cggcactggt ggagaagaag gaaagtttga
     6241 tcaattgctg tgtcaaagta cttccgcctt gcagtccgcc agaggtaaag ttagagaggg
     6301 cagaaccgat gatccgaata gggtcaaccc cgatgtgttt ataaaaacgg cgatcttcta
     6361 ccgacacgat cgcatcttct aatgttttcg gtaattcatt cgcagaaatt ttttcacgct
     6421 tttctgcgcc taaatcttcg aatagttcgc catcttgtgt atatagtttg gaagatacgg
     6481 tagcgtctaa ttttttatcc gtcaattcgg gcgcatcttt tgcgtaatac cagaaaagtc
     6541 ctacacctgc taaaaagagg atacagaaaa atgagagtat tcctaaaagg atcttgataa
     6601 ataatccttt tttatgtgtt ccagaggact ttccagaacc tttgccagaa ttcttcttca
     6661 cactcttttt aggagtaggc tgtttctgtc gtctagagct tctagtttgt tcatttgcca
     6721 ttcttgcttt ctccttcaat agataatgtt gataaataga agtcaaccgc gtccaaataa
     6781 ggaatccgcg gagaaatacc agttttgatc tctattccta gttcttcgat caaagataaa
     6841 ggtagtgatt tgcgtccttt ttccttttgg gcgtcccagt aagcaatcaa atgaacacta
     6901 ttcaaataaa aacagcgctt caaagacgaa aaccataaca agacaaagca gaccccattt
     6961 tgttcgaggc atgctttcat atgttcgatt tgatgggcat ggaagttttt aaagggaaaa
     7021 gatgttttgt tcttggtttc ttttgcttca aagtccaagt aaaagcctcg atagacgcca
     7081 ttatagtctg tagttgaggc ttgggtaaag taggcttcct tgatcacagc agcacttctc
     7141 ttaggatagt ctactttcac gatttggata ggggtaggct ttttatggat aaccgccaac
     7201 ccgcgggaaa gataatattt attactttca ttgattgctt cttcaaagcg catcccccga
     7261 ttgccgaatt cagtgatctg atttcttttt tcttgaattt tttcgacggg agaggcattc
     7321 ttataataag gttggccatt tggatagcgc aataccatct ttaatcacac tcctaggcca
     7381 cattatagca aaaaagcgga tagaaagaaa aggaatctga gatggataag tcaaaagtaa
     7441 tctatgtgtc tgggtatcga agtttcgaac tcggtgtttt taaagaaaat gatcctaaaa
     7501 tccaagttgt taaaaatgtt ttaaaaaaag aactccatca gttagcagaa gaagggctgg
     7561 aatgggtact tgtcagtggg aatttgggcg tcgaactatg ggctgtgcaa atagtagcgg
     7621 aattgaaaga agaatatccg gaactatctc ttggtatttt gtatcctttt tctgattttg
     7681 gtaataactg gaatgaaggg aaccaagaaa aaaaacaatt agcagaacaa ttagcagatt
     7741 atgtcgaagc tgttagccat caaccctacc aatcacctag tcagctaaag aatcacactc
     7801 gttttatact tgagcataca gtgggctgtc tgctgatcta tgatgaagaa ttccctggaa
     7861 aaacgaagta tttttttgaa gatgcacaga attaccaagc agatcatccc tacgaaattc
     7921 ggctgatcag tatggacgat cttcaaaatt ttagtgaata atcgatattg tgtttgattt
     7981 atcaactttt ttcctataca atgaaaaagg tagaaatgtt attacgtaaa tgaaaactag
     8041 aggtgtaaat atggcgaatt tggtttatag tcctaaagac attttacaac aagaattcaa
     8101 aacaaaaatg cgcggctatg atcccgttga agttgatgaa ttcttagaca atatcatcaa
     8161 agattatgaa acttacagca aagaactcct tgctttacaa gaagaaaacg atcgattgag
     8221 tgcaaaagta gctcaattat ctaaaactca aggagcagct caaacacgcg tgcaacaaac
     8281 agaggcacca aagagcgcag cagtgaccaa ttttgatatc ttaaaacgct tgtcaaatct
     8341 tgaacgtgaa gtatttggta aaaagcttga tcaacaagca agtgcagtca aaccagcaca
     8401 acctaatcca aataactaca caaatgcaga cacaagctta gatgataatg aaaaaacacg
     8461 tcaattttaa tttttgatta atgaatttgc ggttttcggg taatcgcggt ctgacttgat
     8521 caggctgagg aaagtccatg ctcgcacagg ctgtgatgcc tgtagtgttc gtgcttagcg
     8581 aaaccataag ctaaggtact ctttggagta acggcaggaa aacaagctaa ggcttcggct
     8641 atgcttaagt atccttgaaa gtgccacagt gacgaagcgg ctggggaaac ccatccggtg
     8701 gaacgcggta aacccctcga gcgagcaacc caaacaatgg taggggcgct ttttgtctgg
     8761 aagaagaaca ggacaaaaag gcagtataac tgcagataga tggttaccgc tttgtttttt
     8821 ctccctggaa aagcaaagta cagaacatgg cttatagaaa accgcaaaca tcagggaatt
     8881 aggtcgtgac aaaagtaatg cgttataaga aacaagaaaa acatttgaaa gctatttttc
     8941 aatacttcag atgaatcgtt cttattacaa aacaaacttt tgtatcaccg gttattcgga
     9001 atttgagtaa aagtgtgggg taggactgat gtcccacctc ctttttttat aaataaggag
     9061 attgtgtatg gaaaaaaaca ggaagttcaa cctcgtcgca actgcggcaa gcgggctaga
     9121 agcactggtt ggtaaagaat taagagatct tggaatcgaa tgccaagttg agaacggacg
     9181 tgcacgtttt gaaggaacaa tggaaacgat cgctacagct aatttatggt tacgtacagc
     9241 agatcgagta aaaatcgtgg ttggggaatt cgatgcgtat acgtttgatg aattgtttga
     9301 aaacgtaaaa gcattgcctt gggaagattt tcttccacta gatgcagctt ttcctgtagc
     9361 tggaaaatcg atcaagtcga aactatatag cacacctgat tgccaagcga tcacaaaaaa
     9421 agcaatcgtt gaacgtctcc gtacctatta tcaccgtcca gcttctgtac cactgacgga
     9481 aactggcgca cattttcagt tggaagtagc tttgctgaaa gaccatgtga tggtaactct
     9541 ggatacgaca ggaccaagtt tattcaaacg tggttatcgc ttagaaaaag gtggagcacc
     9601 attgaaagaa aacatggcag cagcacttat tatgttgaca aattggcgaa aagaccgtcc
     9661 attttatgat cctgtatgtg gttcaggtac gctttgtatt gaagcagcct taataggcca
     9721 taatatcgca ccaggattca atcgtgagtt tgcttgcgaa tcttgggatt ggttcagtca
     9781 agaaatcatg gaaaatgttc gatcagcagc cgaagaaaaa gcagattatg atattgaatt
     9841 agatattact ggttcagata tcaatggacg gatgattgaa attgccaaag ccaatgcaga
     9901 agaaatcgga ttaggctctt cgattacctt taagcaacaa gcagtcaaag acttcaaaac
     9961 ggataaagaa tacggggtca tcgtggctaa tccgccttac ggagaacgtc taggagaaga
    10021 agaaactgtt cggaaattat ataaagaaat gggcgatgta ttccgtccat taaaaacatg
    10081 gagtaaatat atcttgacta gcgacttagc gtttgaggaa ttttacggac aaaaagcaac
    10141 caaaaaaaga aaattgtaca atggtgcatt gcgtacggat ctattccagt attggggaac
    10201 tcgtccgcct agaaaaaaag agaaagacga ataatcttac taattgattc attcaattgg
    10261 atgtttggag gaatagggaa tgaaagaaaa agagttttta caagaagtaa aagaaatcaa
    10321 tcttctacaa caagctttag gaatcctcga ttgggataca caaacaggta tgcctgaaaa
    10381 agctagtgca taccgaagtg aagtagacag ctatctttac agcatttatt tttcaaaaaa
    10441 aatcggtcca aaaatcaaag aagccattcg ctatttttct gaacatccgg aagaattgtc
    10501 ggaagttgga actgccgttt ttgccaaagt aaaagaagag tatgatttgg aacatcgcgt
    10561 accggaagat cttatgagaa aatatacagc tgccgtttct tcagcacacg gacaatggca
    10621 aaaagctaga gaaacacaac aattttctga ttttcaacac gcattgaatc aaaatattga
    10681 attaacaaaa cagttgatac cttactggag aaaagatgaa aagacgaatt atgatgtttt
    10741 gctgaatcaa tacgaacccg ggatgactgt cgaaatcctt gataaggtat ttgatcagct
    10801 taaagaagga attctttcga tccgccgtac gctccaagaa aaagggactg aacctgaaac
    10861 agacttttta aatcggagaa tgacgaaaaa acaacagaag agatttgtag tgaaagtaat
    10921 cgaacaactt ggttatgatt ttagtcgtgg tcgtttagat gacactgtcc acccatttat
    10981 gactggaatt aatccgaatg atgcacgaat cacgacacga tggaacgaaa cagatttcaa
    11041 aatggctgtt tttggagtga tccacgaggc tggtcatggt atgtatgaac aagacatcga
    11101 tgataaatat gcgtatacac cggtttatga aggtacatca atgggtatcc atgaatcaca
    11161 atcgttgttt aacgagatca ttattggaag tagtcgcagc ttctggaaaa agcaatatcc
    11221 tttctttcaa gaatgtgcag aaggaacatt cgatgatatt ccttttgaca aattttatcg
    11281 ttcattgaac catacaaaat caagtttggt tcgtatcgag gcagacagtt tgacttaccc
    11341 tctccatatc atcattcgtt atgaaatcga aaaaatgatt ttcaatgaag gggtagatgt
    11401 tgctgaacta cctgaaatat ggaatcaaaa atatgaagag tatctgggaa tacgaccaac
    11461 aaatgatgtg gaaggcatcc tacaagacgt tcattggtca ggtgcaagct ttggttattt
    11521 tccctcttat gcattagggt acatgtatgc ggcacaatta cttcattctt tgcagcaaga
    11581 aatagatgtg gaaaatgttc tagcgtcaga cgattattct ccaatcaaaa actggatgtc
    11641 agagcatatc catcaatatg gtgcatctag aaaaccaaat caattaatca tggatgcaac
    11701 acatgaaccg cttaatccgc aatacctgat cgactatatg aaagacctgt attttaatgt
    11761 atatcaggta aaataaaata caatttacaa agatagctga aattcatcta atctatagat
    11821 gttttcagct atttacttaa gaaagaagtg gaacgaatgg ataaattaca agtgatcgct
    11881 gattatagta tggaccaatt agcgcatgat caaacaggac atgggagcga tcataccaaa
    11941 agagttgtca agttagctga aaaaattttg gagacggaac cgcaggcaga ccgctttgtg
    12001 acgcttgcag cagcttacct acatgatacg attgatgata aagtcgttaa aaatgagaac
    12061 gaggcaaagc aacagcttcg tgtattcctt cgctctttgc caatagtaga ggaacagatc
    12121 tcgatgattt tttccattat cgaaaatatg tccttttcta aaaatctctc tgaagcggcc
    12181 gaactatctc tggaaggtaa gatcgttcaa gacgctgatc gtatcgaagc attaggagca
    12241 atcggcattt tgcgtactgc ttatttcggc ggtggacatg ggcacccgat ttttgatcct
    12301 gaactgtatc cgcaaacatt caaggacaaa gaaaattacc gaaaaggcac gacagtgatc
    12361 aatcattttt atgaaaaact gttcttgctg tctgataaaa tgaatactga ttacggatat
    12421 gaagaagcca aacgaagaga aaccttcatg cgtgaattct tagaagaatt ttttctggaa
    12481 tggtctattg acgatgaaaa ttttactcca gacaattgga tcaaaaataa caaaaaatga
    12541 tggaggttgt gacagaagtg gtcagctcca agatatttcg gatcattttc cgtaaaagtt
    12601 acttctggaa cactgtttac caagaggtcg tgagcctgcc gttcagctcc gagtcacaag
    12661 gaacaatttc aaaaaatagc ttctcgtgtt tgatgaatat tgtaacttgt gattcggaat
    12721 tggcaggaga acaccgttta ttcggaagaa taggactgtg acaagacttt tgtcacagtc
    12781 cttttttcga attcaacaag taaaactttt aagaaatatt cagagagtaa aattaaaaat
    12841 tgctgataaa cgaagatgga aattttatgt atttttattg gtctatgcaa taaataaatt
    12901 aaatattcag aatacaattg attttaacga aagggcttct atcaatggtt gtgttgtatt
    12961 tatctgccca ggtagagtaa aatagatcat tatctaaaag gtaattgttc atactatata
    13021 agtcatttga aagtaaaaag atactgtaaa taaaaaatgt ggttaaataa ttctcataat
    13081 cagtgtaagc gttatcaaaa atatagcata cttgctttgt agatgaatga cacgatatat
    13141 gtttggtatg ttctgcaaga cagatgaata tggaggtgga gacaatgtct tccaaagaac
    13201 taacaatgta tttagagaaa gaattggatc aactgaaaga aaaggggtta tacaatacga
    13261 tcgacatact agaaagtgaa aatggtgctt gtatcatcgt agacggaaaa aagatgatca
    13321 atctagcatc caacaattat cttggatttg ccaatcgcga agaattgaaa aaagcatgta
    13381 ttgaagcaac cgaaacttat ggtgtaggag caggagcagt ccgaacgatc aatggttcgc
    13441 tgaaaatcca tcagcaatta gaagaaaaaa tcgcagaatt caaagggaca gaagcagcaa
    13501 tcgcctttca atctggattc aactgcaata tgggcgctat ctctgcagta atgacaaaag
    13561 aagatgctat cttatcggat gaattaaacc atgcatctat tattgacggt tgccgcttat
    13621 ccggagcaaa aatcatccga attaaacatc aagatatgaa agaccttgag aaaaaagcaa
    13681 aggaagcgat agaaagtaag aaatataaaa aaatcatgta tatcacagat ggtgttttct
    13741 ccatggatgg agacattgca cgattgccgg aaattattcc gattgttgaa aaatatggac
    13801 tgatcaccta cgtcgatgat gcgcacggct caggcgtaac tggaaaaggt gcaggaaccg
    13861 tcaagcattt tggattaagc gacaaaatcg atatgcaaat gggcacgtta tcgaaagcta
    13921 taggtgttgt tgggggttat gtagctggat cgaaaacact aatcgactgg ttgaaagcta
    13981 gaagtcggcc attcctattt tctacttcgc taactccagg tgcagctgca gctgcattgg
    14041 cttcgattac tttgatgcaa gaacatccgg aacttgtcga aaaagtttgg gaaaatgcta
    14101 attattttaa agaagaattg aaaaaagtag gctataacat cggtatgtct gaaacaccta
    14161 ttactccagt cattttggga gacgaaaaag tgactcagac tttctctaag aagctgatcg
    14221 aacatgggat ttatgctaaa ccaatcgttt atccaactgt gcctcttggg acaggcagga
    14281 tcagaaatat gccgactgcg gaacatacga gggaaatgct tgatgaagca gtagcagttt
    14341 atcaaaaaat aggaaaagaa atggaaatta tttaactaaa tttagttttt tcgtctattt
    14401 aaaattagag aacatgttca cgcatatatt gttaatcatc tgaagatagt agtaaaaaag
    14461 atcagggagg atcatcatga aaaaagtatt ggtgacagga tgtttaggac aaattggttc
    14521 agagttgatc acacggctac gtcaagaact aggcagtgaa aatgtcattg cgacagatat
    14581 acgcatgcct gaagtcattg agaaaaacga tatctttgag atcctagatg taatggatta
    14641 cgaaaaaatg cgcagcatag cagaacaata tcaagtggac acattgattc atttggctgc
    14701 tcttttgtca gctgttgcag aagcaaaacc acaattagcc tggaatttga acgtgactgg
    14761 gctggtcaat gcattggaag tcgctagaga attccagctg aaatttttta cgccaagttc
    14821 aatcggcgcg tttggtccaa atactccaaa agatcatacc ccacaagata ctcttcagcg
    14881 tcctacaacc atgtatgggg taacgaaggt agctggagaa ctactatgtg attattatta
    14941 tgtgaaatat ggcgtagata ctcgtggtgt ccgtttccct ggattgattt cttatgcaac
    15001 cttgccagga ggcggtacga cagactacgc agtcgatatt tattattcag caatcaaaga
    15061 aggaaagtac actagtttca ttgatcaagg tacatcaatg gatatgatgt atatgccaga
    15121 tgcgatcgat gccattataa aactcatgaa tgcagatcct gatcgattgg ttcatcgaaa
    15181 tgccttcaat atatcggcga tgtcttttga cccggaagag atcaaagcat ctattcaaaa
    15241 aatcatacca gattttgaaa tggattatga tgtggatcct gtacgtcagt caatagcaga
    15301 atcttggcca aattcactag atgtttcttg tgcgcaagag gaatggggct tttcgccgaa
    15361 atacgactta gatgtgatga caaaggatat gttggaaaaa ctgaaagaaa aattggtaga
    15421 gacggtataa aacaagaacc acatccaaaa agttttttat acttttggga ttggctatgg
    15481 tatgaaaggg gacaagggat ggaagaatat caagccacgc cagtaaaaga agtaaaaata
    15541 gaaaatgaat taaaacgtac gatgggattt tttactgctt tatcgactgt tatgggcaca
    15601 gtgatcggtg caggggtatt ttttaaagcc gcaagcgtag cagaagttac aggatccgcc
    15661 agtttgcata tgttttcttg gtttctcggt ggtatgattt ctgtctgtgc aggactaaca
    15721 ggagctgaac tggcagctgc tattccagaa acaggaggga tgattaaata tatcgaacgg
    15781 atttacggaa atacagcagc ttttttattg ggctgggcgc aagtcgtgat ttattttcca
    15841 gcaaatgtag cagccttgtc gatcattttc ggtacacagt tcgtcaatct atttggtctt
    15901 tcccagtcaa tgattgttcc cgtagctgtt acagctgctg tatcgatcct gttgatcaat
    15961 tttttaggtt ctaaagctgg aggggctttt cagtcgatta cgcttgtctg caagcttatt
    16021 cctttgtttg tgatcgtcat tttcggtttg ttccgacaag aaggagtaga cttccaactg
    16081 tttccgatcc aagcaggaga aaatctttca tttttctcag ccttgggagc gggcttgcta
    16141 gcaacgatgt tcgcatacga cggttggata cacgtaggaa atatttcggg agaattgaaa
    16201 aagccggcga aagatttgcc aaaagcaatt tctttaggaa tcatcggaat catgatcgtt
    16261 tatttattag taaatgcggt gttcttaaga accgcatcta tcgacggagt cgcaggaaac
    16321 agcaatgcgg caagtgacgt tgcaaaaatg atttttggcg gcttcggtgg aagactggtc
    16381 acagttggta tcttgatttc tgtttatgga accatcaatg gctataccct tactggaatg
    16441 cgtctccctt atgttattgc aaaagaaaac aacctgcctt ttagcaagct ctttgctaaa
    16501 cttcatgata aaactaaagt tcctgtagcc gcaggtatct tagagctagt catcgctatt
    16561 ggcatgatga tgatcggtgg ttttgataca ctaacggata tgctgatctt tgtcatttgg
    16621 attttttata cgatggtctt tgttggtgtc attcttcttc gtaaaaaaga acctgatttg
    16681 tttcgaccat acaaagttcc aatgtatccg tttattccac tagtagcaat cattggaggg
    16741 acttttatcg tatcaagcac gcttatcact cagacctttt tagcttcgat ggggatagta
    16801 ttgacacttg ctggtatccc gatttatctc tatttaaaac gtagatagct aaaacattcg
    16861 aattttatta gaactgcact tctctgccaa acaaaatatt ttatttaaat gaggagtacg
    16921 tggaagaaat gtcaaaagta ctcgttaatt ttgatcacgt aaatgtcgtt ttgtctacga
    16981 tgaaatagca aagtaaaaga cagaaatcgg gctcaaccga tttctgtctt ttactttgat
    17041 ttgcgtaact gaactattcg gcgtacgccg cgataaatat ttaataaaac caagcaacca
    17101 gaaatgaaaa tgggaagcca aatcagatag acagggtagc caagcacttt agacaaagca
    17161 tgtggagtca ttttatccat ttcaagaagt gcttgctgcc aagtctgaag attgaagact
    17221 agcatgaaac ccgaaataat caggagaata aatcctaaat aatgaattgt agttcttttt
    17281 cttacataag cgatcgtagc ataaaggaac agtaaaaaaa taggtacgcc aaaaacaaag
    17341 tacatattca gcatctcgac accccctttg tgtttatctt actttacttt gaaagaaatg
    17401 agaaataata gcctcgttac ttgcttgaaa cagcaaagga ctgctaagat aagagagata
    17461 caaagaatca aggaggagtc atatggcaag ttatatcgaa ccgattcgtt ttgcgctgat
    17521 tgtttttcca tttttagcct tagcgatctc atctgttttt tttatttatg aatatcgaaa
    17581 gtatggaaca tttctagtaa caagggcagt tattttgtat tctttcgttt tttatttatt
    17641 gtgtgcgtat tttttggtga tcttaccact tccggcaaag gagacggttg cccaaatgac
    17701 agggccaaag atggagctgc atttatttgc ttcatggcaa catttcagag acaacacggt
    17761 attggtcttg tctgaaccta gtacctacct gccggcaatg aagcagagtg tatttttgga
    17821 accagctttt aatgttttat tactcatacc atttggcatt tatttaagat attatttccg
    17881 gctttctttt atgaaaacga tgattgctag tttctgcctt tctctatttt ttgaattgac
    17941 gcagctaagt ggactttatt ttatctaccc aagaccatac cgcttatttg atgtgaatga
    18001 tttagtgaca aatacattgg gtggaatcat tggttttgtc gttacgccgt tatttacatt
    18061 tatgcttcct acaagaagac gaatggatga actttcttat gaaaaaggaa agactgtctc
    18121 attgactcga cgcttggtcg cttatttgat cgactggaca tttttatctc ttattaattt
    18181 ggtagcggcg attttcttta aaattgcgtt cgattcaggg gcagttactt ctcatatctg
    18241 gtggctttta ttagaagtag gggtatactt tatgattgta ccgtttataa ccaatggatg
    18301 gacacttggc aaaaaaattg tgcgtatccg tttggtggaa gaagaccgcg aacgaatttc
    18361 tttaaaagca ttgatgatcc gctacgggta tctgtacttt cttttttatg gtttaagctg
    18421 gttggggcag ttgcttcagc aaatcatgaa ttcgacaacg aatacggtgt tgcagatgag
    18481 tgcagtattc atttctctcg gtgtcttgtt actacaaggt atttttattt taaatatctt
    18541 gctatcattt ttgagaaaaa aacggattct gttttatgaa aaagctagtc acacatatac
    18601 tgttagcacg attggccaaa caaaggatga tgattctcga aattagctga gcaaaaacgc
    18661 tttgtctgtg ttataatgcc aaagtcgtga taatttaaag agaagaggtg cacgaatgaa
    18721 taattttgat atattccgct tcaaaccgtt tatcaatgaa gcgttaaccg caaagggctt
    18781 caaacagccc acagaggtcc aggaacgttt gattccttta attgcaaaag gaaaaaatat
    18841 cattgggcaa tctcaaactg gtacaggaaa aacacatacg tttttgttgc ctttgtttga
    18901 aaaaatcaat gcagaaaaag aggaagtaca agttgttatt acagctccaa gtagggaact
    18961 agctgcacag atctatgaag cagctacaca aatcgctaaa ttttctacac cggagatccg
    19021 tgtctcgaat tttgtcggcg gtacagacaa acagcgtcaa ttaaatcgtc tgcatcacca
    19081 acagccacag gttgtagtag gcacgcctgg tagaatatta gacatgatga atgaacaagc
    19141 gctgaagatt cacaccgcat ttgcatttgt tgtcgatgaa gcggatatga cattggatat
    19201 gggtttttta aatgaagtag accaaattgc aagtcgatta ccagaaaagc tgcagttttt
    19261 agttttttct gccactattc cagaaaaact tcgtccattc ttacgaaaat acatggaaaa
    19321 tccaatcatt gaagaaatca aaccaaaagc agttatttct gaagacattg aaaattggct
    19381 gatttcaaca aaaggtaaag atgagaatca aatgatttat caactgctga caattggtca
    19441 tccttattta gcaatcgtat ttgccaatac aaaacagcat gtggatgaaa ttgccgatta
    19501 cttgaaaaac caaggcttga aagtagcaaa gattcatgga gacatcaccc caagagagag
    19561 aaaacgagtg atgcgacaag tacagaatct ggagtatcaa tatgttgtag cgactgattt
    19621 agctgctaga gggatcgata tcgaaggtgt ctctcatgtt attaatgcag aaattccaga
    19681 agatctagac ttctttatcc atcgtgtcgg acgtactgga cgtaatggct taaaaggaac
    19741 ggccattacg ttatattcgc caaatgatga gcaagccatt gatgcgatag aaaaattggg
    19801 cgtctcattt gaaccaaaag aaatcaaaaa cggggaaatc gtcaaaacat acgatcgtaa
    19861 tagacgtgcc aaacgagaaa aatcaaaaga tgtattagat cccacgctga ttggtcttgt
    19921 gaagaagaaa aagaaaaaga tcaagcctgg ttataagaaa aaaatcgatt gggcaattgc
    19981 agaaaaaaat aaaaaagaac gcaaaatcga acgcagacag caaagccgta ctgctcgtaa
    20041 aaataagaaa aattcacata aataaaaaac aagaggttgt gacaaaaggc gtgtcacaat
    20101 ctcttgtttt taagctagac tttttttcat tccgatacaa agtacttcat cttcaataaa
    20161 aggttctgtg caagtatgat acccttgttt ttcataaaaa tctacagccg tcatttcagc
    20221 tactacataa ctagtctgac aaccttctga aaccgcccgt ttttcagcag cttcaagcaa
    20281 ctgaccgcct aacccttttc ctcggtattc ttttgctacg caaaatcgtt ccggcttgaa
    20341 gcaagtaggt gttttctttt cataacgcaa agtagctact ggtctttttt gatcaagaaa
    20401 tagataatag gtttgttgcg ggatatcttt tccgtcgaat tctagttctg caggaatccc
    20461 ttgttctaat acaaaaactt gatatctcaa aaagcagcta gctgcgcgta tccattcatc
    20521 cgctccaact atttttttca tcatattcct ccttgtcatg aatagcagag atgtattgat
    20581 tcctttattc ttatcgtacc aaaaatcgtg gagtatgacc aaaaggaaat gaaaataaaa
    20641 attgagatat tgacagtgat caatagaatg cgtatactaa ttaagtacga aaaggatatg
    20701 atttgttttt taagactcac agaaaattct ttcttggctg aaaaaagaat agtcactaat
    20761 caaattgctc cctttttcta ttttggtaga aataccgacg cagctcagcg ttatcgagtt
    20821 taagaggtaa tgattacaca tcattgcaat caaggtggta ccgcgagttt tcgtccttgg
    20881 ctgtgatggt gtttttttgt atttaattta tagaaagcag gtaatgacat gaaacaatta
    20941 agtagtgcac aagttcgaca aatgtttctt gatttcttcc aatctaaagg acatacgatt
    21001 gaacctagtg cgtctttgat ccccgtgaac gatccaacct tattgtggat caactctggt
    21061 gttgcaacat tgaaaaaata ttttgatggt tcagttgtgc cagaaaatcc aagaatcaca
    21121 aatgcccaaa aatctattcg aacaaatgat atcgaaaatg tcggtaaaac agcacggcac
    21181 catacgatgt ttgagatgct gggtaatttt tcgattggtg actatttcaa aaatgaagcc
    21241 atccactggg catgggaatt tttgactgat ccaaaatgga tggcattcga tccagaaaaa
    21301 ctttatgtaa cagtttatcc aaaagataca gaagcaaaac gcatctggca tgaagaagtt
    21361 ggcctgccac tagatcacat tattgatgta gaagacaact tctgggatat cggtgcaggc
    21421 ccatgtggtc cggatacgga aattttctat gaccgtggag aagcttataa cgatttagca
    21481 gaagacgatc ctgaaaacta tccaggagga gaaaatgaac gttatttaga aatctggaac
    21541 ttagtatttt cagaattcaa ccataagcct gataacacat ttgaaccact tcctcataaa
    21601 aacattgata cggggatggg attggaacgc atggtctcaa tcgttcaaga tgcgtcaacg
    21661 aactttgaga cagacttgtt tatgcctatt atccacgccg tagaaaagct aagcaaacaa
    21721 gtaaaatatg gtgaaaaccc agtaacagat atttcttaca aagtaatcgc agatcatatt
    21781 cgcgcccttt catttgctat tggcgacggt gcattgccat cgaatgaagg gagagggtat
    21841 gtcttacgcc gtttgcttcg tcgtgctgtc atgcatggga aaaaattagg tattgaacaa
    21901 gcattcttat atcgtttagt ccctgttgtt ggggaaatca tggtaagtta ttatcctgaa
    21961 gtacttcaac aaaaagaatt tattgaaaaa gttatccgta cagaagaaga acgtttcaat
    22021 gaaacaatca atgaaggttt ggaaatctta aatcaagtga tccaagaagt aaaaaacgaa
    22081 aacgggacga ctctagcagg aaaagacatc ttcaaactat acgacacata tggcttcccg
    22141 gtagaattaa cggaagaggt ggcagaagat gaaggactga aagttgatca tgctggtttt
    22201 gaaaaagaaa tggatgcaca acgcgaacgt gctcgctctg cccgcagtac tgaaaaatca
    22261 atgggggtac aatctgcttt attgacagat atcaaagtag aaagtaaatt cattggatac
    22321 acagaacaag aatcagatag tcaattattg gtcatcgtta aaggtgagtc tcttttgaat
    22381 gaagtcgcag aaggtgaagc tcaaatgatc tttgatcaaa cacctttcta tgcagaaatg
    22441 ggtgggcaag tagcggatca aggatggatc atgaatgaag taggcgaaat cgtagcagtt
    22501 gttacagatg ttcaaaaagc gcctaatggt caatttatgc acaccgtaga agtaaaagca
    22561 ccaatgagtg aaggacaaac ctatcatcta ttgatcgatc aatcgatgcg caatcggatc
    22621 atcaaaaacc atacagcaac ccatctactg cacaaggcat tgaaagaagt acttggcgag
    22681 catgcaaatc aagctggttc tttagtcgct cctggacatt tacgattcga ctttacccac
    22741 tttggtcaaa tcacttcaga tgaattagct gaaatggaaa gaatcgtcaa cgaaaaaatc
    22801 tgggaagcta tcccagttga aacaattgaa acagatatcg atacagccaa aaacatgggt
    22861 gcaatggctt tgtttggtga aaaatacgga catgacgttc gagtagtaaa tattggcggc
    22921 tggtcaatcg aactgtgcgg aggcacacat gtagcaaata cagaaaacat cggaatcttc
    22981 aaaatcgttt ctgaatcagg aattggtgca ggcgtgcgac gaatcgaggc tgtaacaagt
    23041 aaagaagcgt acgaactact tgaagaagaa gaaaaacaac taaaacaagt agcaacaatt
    23101 gttaaatcac ctcaattgaa agaagttgtt tcaaaagcgg aacaattgca acagcaagta
    23161 agagagctac aaaaggaaaa tgaacaatta gctagcaagt tagcgaatca acaagctggt
    23221 gatgtattca aagatccaga aacgatcaat ggaaaaacaa tcattgcagc acaagtaaaa
    23281 gtgaaagata tgaatcagct gcgtcaatta gctgaccaat ggaaacaaaa aaatatttca
    23341 gatattcttg ttttagcaaa cgaacaagaa ggaaaagtca gtctgctagc ggcaatgacg
    23401 aaagaatcaa atgaagctgg actaaaagct ggcgacttga ttaaagcaat cgcaccgaaa
    23461 gtaggcggtg gcggtggtgg acgtccagac atggcacaag ctggcgggaa aaatcctgct
    23521 ggtattccag atgcacttaa agctgcgaaa gaatgggttg cgcaacaata gggcgtttac
    23581 gtttgacaga aaaacaaaag ttcaaacatt gaacgaaaca tgattatggg ggcgaagaca
    23641 aacaagtctt gccctcatac ttttttcaat tggatggcgc atctaatcaa atggtcggat
    23701 tcggatggtc tttagttgac gaaagtgaca gaaattttta cgattagtat aaataaaaag
    23761 gggtgaaaaa atgaatagta gaaataagac ctttcgacta gtcttacgtg cgatcttgtt
    23821 agcaatcatc atcgtacaag cgatggttcc ttggctgggg tttattccat taggattcat
    23881 tagtttaaca attatccata tcacagtaat tattgctgca gtagtattag gcccaaaaga
    23941 tggcatggtg attggcttgt tttggggaat cgctacaatt gttcgtgcct atgccatgcc
    24001 aacaacgcca tttgatacat tagtgttcac gaatccgatt atctcggtag ttcccagagt
    24061 acttgttggc ttagtagcag gcttggtttt ccactggatt tatcaaaaaa ataaatcaat
    24121 aacgatcagc tcagcctttg caggggtact gggttcattg gtcaatacag tcttagtgtt
    24181 aggattcatg ggattatttt atacaggtgc aacggcagat gcctatggtg tagactctgc
    24241 tcttttattt aaaaccttag caggggttgc agcaatcaat gggataccag aagcaatagg
    24301 tgcgggaatc ataacaccat tactagcaaa agcgttattt gcagcaacac cgttgaaacc
    24361 agaataatga ccatctttta atagtaatag gacgcacgat agatagaaaa aggaagagag
    24421 gagaggaaaa caatcgtcct ctccatcttt ttacctgagc aacaagcaaa ctagaagggg
    24481 taaaaaactt ggctaagaaa caagaagaaa aaaagaaaca aataccgcaa cagcggacaa
    24541 aaaaaggagt actagcgggt atcttaggat tggttacgaa tctgatcttg tttgtctcta
    24601 agctaatgat cgggcttttt tcaggaagtg tctccattat ggctgatgca gtgaacagtc
    24661 tatcagatac tgcttcatcc atattgactt tgatcggatt taaaattgct gcaaagccag
    24721 cagatcagga acatccttat ggacacgaac gcttcgaata tatcagtggg ttatttgttt
    24781 cgatcatcat tacttatgta ggatttcaat ttttagagtc ttctgctgaa aaaatcatcc
    24841 atccagaaaa tgtctcttta acacccatcg tcttttttgt cctaatcatt tccatctttt
    24901 tgaaatttgc acaaggcaaa atgtatcagg ttattgcgca atccattgat tctgaaacat
    24961 tgagagctac agcaacagat agttataatg atgtctttac tacactggct gtattgcttt
    25021 cagcagcaat cgaatgggta actggatggc gtattgatgg atatataggt tttgctttag
    25081 cattatatat cctttatagt ggattgacga tgcttcgaaa ttttgtatac gaactattag
    25141 gaagtcgccc aacgccagca gagattgaag aaatggaaga gcatttaaat gcttgcgatg
    25201 atatacttgg ctatcatgat ttattggtgc ataactatgg acccaataaa cgctttgcat
    25261 cagtccacat cgaagtagat gaatcaatga atttgaatgt ggctcataag attattgatc
    25321 tgatagaaaa agactttaaa aagtctttgg atgtggaact tgtctgtcac ttggatccaa
    25381 tgcctgttga taacgaaaaa tactataata tcttgcggca gttaaagcaa attcttcttg
    25441 aaacaggtac agggcttaat attcatgatt ttagagtaat tcatcaagga aaaacgctgc
    25501 aatttgatgt agtggtccct gagaaattcc agtttgttga tacagaacta gaaagaatct
    25561 tacgtagtca aatagaagaa aaaatcggag attaccaatt ggaaattacg tttgatcaca
    25621 attatctttt atattaaatg agaaactata aaaagactcc ttaaagtttt taatttaaag
    25681 agtctttttt tcttttaatt gtttatggag agcctgacgt gcaagattat ctgctccttt
    25741 atttttgttt tcgggcaacc attgcaggat caataaagaa aattcggata gaagttcttg
    25801 gattctttga aggtagggaa ggaagagctc gttcttcgtt gcgtttttgt cgaccgtaga
    25861 aactagtgtt ttgctgtctg aaaaacagaa aatcgtttca ttctgtaagt cgtttttctt
    25921 tagaaattct aaagttttta aaaagacttc gaactctgct tgatggtttg tccctataga
    25981 aagcgggata gatagctgtt cttgtttacc ttgatagaca atcaagattc cacctccact
    26041 aggaccaggg ttgccttttg tagaggcatc aatgtatact tttaacataa aaagagattc
    26101 tcctttttgt tcaaactaat gttatggtaa gattatatca ttactgaatc ggtgagaggt
    26161 tagagaatga aaaaaaatat tcgatggcag cctgaactgg cacatacgat catctattgg
    26221 tcattgacct tgatcattct gttttttagt ctgattcttt ctttagaaaa cacaggtcct
    26281 tattggaaaa gcaattttgt tttaggtatt tttcttgttt ttctatttct aggtttgcgg
    26341 cgttctttta ttttaaaatc aaactctgtg attatacgtt atgctgcttt ttggaaagac
    26401 cgagaaatat ctgtcggaca gattcgatct ttgacgccaa ctaatactgg ggtgcaaatg
    26461 atgttgcaag atgagaaagc cccatctgtt ttcatgatgc gaaaaaaaga tcaagtagtc
    26521 ctttttgatc attttgaaaa aaacggaccc aaatcagaat caattcctta tccttatacg
    26581 aaaaaaagaa aaagctaatt ttaaaaatca gaacctaaaa aaacgaattt ttacaggaaa
    26641 agaaaagagt gagacgtacg gttcatcccg tttagcgtct cactctattt gtttatctat
    26701 tcatgcatac tagtatcggt agtctgaacg ttgcctttct tgacatgggc agcttgtgtt
    26761 cctcgattcc cttcgatgat ctcaaattcg accacttgat tttcttccaa agttttgaat
    26821 ccctcttctt caatcgcagt aaaatgtaca aaaatttctt ctgtgtcatc ataactgata
    26881 aagccgtatc cttttttgtt gtcaaaccat tttacaattc ctgtggtcaa agcactcacg
    26941 acctttctaa agtctgatca tagccttcat tataaagagt atttataagt acgtcaaata
    27001 aattaaaaac ctgtaatttt atgttttttt tctgaataaa aaaaggtata attggcatat
    27061 cttaacaaag aagatatttt gttgaataaa gttcgtgaaa aggggtaatc aaatgaagaa
    27121 tgatctgcaa atttcacaag aaacagagct agaaccgatt gttgaagtgg ctagtaaatt
    27181 agatcttaag gaagacgatt tggaactgta tgggaaatat aaggcgaaaa tcaatttttc
    27241 tggaatcaat cgatcaaagg ataacgctga ggggcatttg atcttagtta cttccatcaa
    27301 tccaacacca gctggcgaag gaaagtcaac gatcactgta gggttaggag acgcgctcaa
    27361 taaaatcaat aaaaaatctg ttattgcatt gcgagaaccc tcacttggtc ctgtgatggg
    27421 aatcaaaggt ggtgctgcag gcggaggata tgcacaggta ttgcctatgg aagatatcaa
    27481 cttgcatttt actggtgaca tgcatgctat cacaacagct aataatgcat tatctgctct
    27541 tttagataat catattcatc aaggaaatga attgaacatc gatgcccgcc gagtgatttg
    27601 gaaacgggta gtcgatctca atgatcgtga actgcgtaaa gtaattgttg gcttgggtgg
    27661 gccaatccaa ggtgttccaa gagaagatgg gtttgatatc acagttgcca gcgaaatcat
    27721 ggctatcttg tgtcttgcgg cagaccttga agatttaaag gctcgtcttg caaggatcgt
    27781 tgtcggctat acatttgacc gtcagcctgt gactgctgga gacttgaaag cagaaggcgc
    27841 tctggcatta ctgctgaaag atgcaatcaa gccgaatctt gtacaaacaa tttacggaac
    27901 accagctttt gtccacgggg gaccgtttgc caatatcgct catggctgca atagtatttt
    27961 agctaccaag acagcattga gattagcaga ttacgttgtc acagaggcag gatttggtgc
    28021 agatcttggc ggagagaaat ttttagatat caaagtacct aacttgaaaa aagcgccgga
    28081 tgctgtggtg attgtcgcca ctgtccgtgc attgaaaatg catggcggaa tgaaaaaaga
    28141 tgaacttaaa aatgagaatc ttgatgcttt gaaagtaggt tttgcaaatt taaagcgcca
    28201 tatacgtaat atggaacaat atcagctacc tgtgatcgtc gcaatcaatg aattcgtaac
    28261 agatacagac aatgaactca cactgttgga gcacttgtgt gaaaatcagg ggattcttgc
    28321 caagagagcg agtgtatggg cagatggagc agaaggcggc gttgatttag caaaagctgt
    28381 agtacgattg attgatagaa aagaagctaa ttacaagcca ttataccgcc tagaagaaac
    28441 gatacaagaa aagacagaaa caatcgtcaa gaaaatttac ggaggaaatg gtgttgtttt
    28501 cagcaaaaaa gcgcaaaaac aaatagaaga gtttacgaag aatggatggg acaaactgcc
    28561 gatttgtatg gcaaaaacac agtattcatt ttctgatgat ccttcactgc taggtgcacc
    28621 ggaagatttc accatcacga tccgcgaaat catcccaaaa ttaggggcag gatttttagt
    28681 agccttgact ggagatgtta tgacgatgcc tggtttgcct aaaaaacctg ctgcattgaa
    28741 tatggacgtg acaaatgacg gagaagtgtt gggattgttt taagcttgat tataatctac
    28801 catcgaagga gctgtatttt gactacagct tcttttttta gacgataggg aattaatttt
    28861 gtttacacta ggatcattct ttttctttat tgtattttga gctatactaa agcataatag
    28921 gagggtatga tgaaaacgac atttataaga aaaaccggtt tttacggtat gggtagctcg
    28981 attcagctaa gaatcaacaa tgaaaaacgc agtgttctca gtcatgaaca aaagataacg
    29041 cttgatctgg aagtgccctt tacgatgcag gtcacctttt attggctaaa aagccccgtt
    29101 tatacagtga aagaagcaaa gcctgcttat gtgatcacaa tgaattactt gattcttcaa
    29161 atctatccgt ttttatttct agcaactggg ttgggggccg ttttcctaca aaatttattt
    29221 ttcagttttt ttgcagttat tgtgttgatt gcgttctttt tctatataaa aaaccgggca
    29281 tatttgatca aggaggaaaa ttatggcaaa ctctgatctt tttttaatca gtttcaatcg
    29341 aatcgaaaaa tggatgagag acgagatggg aaatgcacga aatatgggat ttaccgaact
    29401 tgtcagacgc ctagctcaaa gaaaacaatt aatgatcaga aaatacgaag atgatctttt
    29461 acagcttgct cagttaagga atgcgatcgt ccatgatcgg atcgcagtcg attttgtcat
    29521 tgcagagcca aatgattgga cagtcaagcg aatccagctg atcgaacaag aactgattca
    29581 gcctgaaacc gtgctgcctc gatttgcaaa acgtgtaaca ggttttgaac aagatcttcc
    29641 gttacttgaa ctgttaaaga tagtagcaga aaaaaggtat tcacaatttc cgttatacaa
    29701 taaaggaaaa tttgtagcat tgattacttt acgtaatatc gggttttggc tagcaaaaga
    29761 aagccaaaaa ggtccggttg atttaacaaa taaacgagcg ttggatttga tcatccaaaa
    29821 cggaaagtac acaaattatc attttgttcc agctaaaaca catatttacg aggttgaagc
    29881 gatgtttcgt gagcaaggga ctttggaagc cgtacttatc actaaagatg ggaatcccga
    29941 tggtaatctg ctcgggatcg tacgacctcg tgatatttat aaacaaatag aaaaggattg
    30001 attttttgtt aattatttat tggatattca gcgctttgct agtaggagtg gatcagttgg
    30061 tcaaatggtg gatcactgat aatctagcgc ttggagagac gaaaaatctt ataccaggta
    30121 ttttgtcact gaatcatatt cgaaacactg gagccgcatg gagtatgcta gaagggaaga
    30181 tgtggttctt tactatagtg acactcattg cagtcgttgt gattctcaca ttgatgatta
    30241 aaaatcgtga aaaaggtaat cgctggttca tgattggatt gagtttgatt ctagctggtg
    30301 cgattggcaa ttttatcgac cgtattcgtc ttggctatgt agtagatatg ttccagacag
    30361 attttatgag ctttccgatt tttaacgtag cagatgtgac acttgtatgt ggagtgattt
    30421 gtatgttaat ttatattatt ttagatgaaa aggatcaaag aaaaaaatga cagaacttaa
    30481 aacgacgatt caccatgaat ctggtaggat cgataaagta ttgactaatt tattcaccga
    30541 ttacagtcgt tcgcaaattc agctgtggct gaaaaatgga gcggtttctg tcaatggaca
    30601 gccagtcaaa gcaaattaca aagtaaaaca aggagacgag attactgtct tgatccccga
    30661 accagaaaca ttagatgtgg tcccagaaaa tatcccgttg acgatcgttt acgaagatga
    30721 agatgtagcg gtgataaaca aacctcaagg aatggtcgtt catccttcag caggtcatac
    30781 gcatggcaca atggtcaatg cgctgatgta ccatatcaag gatctttcta cgatcaacgg
    30841 cgttattcgt ccaggtattg ttcaccgaat cgacaaagat acttccggac tgctaatggt
    30901 tgccaaaaat gaccaggcac acgaatcatt agctcagcaa ttaaaagata agacctcttt
    30961 gcgcaaatat gttgctttag tccatggaga gattcctcac gaaaaaggaa ccatcaatgc
    31021 gccaatcggc cgttcgaagg aaaaccggaa aatgcaggcg ataagagaag atgggaagtc
    31081 ggctgtcaca cattttactg tattggaacg tttcgaagga tttactctgg ttgaattaaa
    31141 actagaaacc ggaagaacac accagatccg tgtgcatatg aagtatatcg gttatccgtt
    31201 agctggagat ccagtatacg gaccgaagaa aactttgaaa ggcaatggtc agtttctcca
    31261 tgcgcaaatg ttaggtttta cgcacccgac tacaaacgaa aagatgatct ttgaagcacc
    31321 tcttccagaa gtttttgaaa aaactttaga aaaattaaga aaaaacattg cattttaatt
    31381 tagataacgg tatagtaatt aacaacgaaa gcataaaact taatagaatt cctttaagtt
    31441 tagtcccgtg aggctaagaa gggtgggagc aaggatacgt atggtgcgcc ataagtagat
    31501 tgctcattga catagtatag ctatcagtgt atcagtatac gctcagtcta aacattcctc
    31561 ctgtcctctt agggcaggag tttttttatg caaaaaagta gggggaatga aaatgcaagc
    31621 aaaagaagta gtagatcagg taaccatgaa gcgagcattg actcgaatta cttatgagat
    31681 tatcgagaga aaccatagta tccaagatat cgtattggta ggtatcaaaa cacgaggaat
    31741 ctacattgca tcaagaattg ccgaacgcct gaagcagcta gaagatatcg atattcctgt
    31801 aggagaactg gatatcactt tataccgaga tgacaaaaaa gaaaatccag aagaaccgga
    31861 acttcattct tctgacatcc cagtttcctt agaaggaaaa gaagttattt tgattgatga
    31921 tgttttgtat acaggacgaa cgattcgagc agcaatggac gcagtaatgg attttggcag
    31981 accaagaaaa atttcattag cagtcctggt cgatcgtggg catcgagaat tgccaatccg
    32041 tgcagattat gttgggaaga acattccaac atctcgggcg gaagagattt tagtagagat
    32101 gcaagagctt gatggacaag atcgcatcat gattttgaaa gaggaagatt agaggagaga
    32161 gaaacatgtc ggagaaaaaa ggatttcata atgatgacgt ggtgttagat atccacgatc
    32221 gcccaacccc aggacattgg gtaggattaa gtttacaaca cttgttcacg atgttcggag
    32281 caaccgtgtt agtccccatc ttagtaggta tcgatccagg tattgcgcta gtcagttcag
    32341 gactaggtac attggtgtac ttatttacta ctaaaggaaa gatacctgcg tacttaggaa
    32401 gcagcttcgc tttcattgca gcgatgcagc ttttgatgaa aacagatggt tatccagcga
    32461 ttgcacaagg agcagtcaca actggattag tctatttgat tgttgcgctg atcatcaaaa
    32521 agatcggttc agcatggctg gataaaatct tgcctccaat cgtcgtcggt ccagtcatca
    32581 tggttatcgg gttgggactt gcggcaaatg cagcaacaaa tgctatgtat aatcagggca
    32641 cgtatgattt caagtatatt gctgtagcgc tgatcacatt aggattaaca attttcttca
    32701 acatgtggct aagaggtttt ctcggattga ttccgatttt actaggtatt attagcggat
    32761 acatcgtagc cttgctgttt ggaatcgtgg atactaagcc aatcgtagac gctgcctggt
    32821 ttgctgttcc taactttgag attccctttg tacaatatga accaaagcta tatcttggag
    32881 caatcacaac aatggcaccc atcgcttttg tgacgatgac agagcatatc ggccatctta
    32941 tggtattgaa taaactaact aaacgtaatt tctttgaaga accgggtctt cataagacgt
    33001 tgacaggtga tggattagca caaatcgtgg cagcctttgt cggaggtcct cctgtaacaa
    33061 gttacggtga aaacattggt gttctggcta tcacacgtgt ccatagcgtg tttgtgatcg
    33121 gtggagctgc agtatttgca gtcattttag gattcgtagg aaaattaagc gctttgattt
    33181 taagtatccc tggaccagtc atctcaggaa tcagttttat cttatttgga gtaattgccg
    33241 caagtggaat gaagatttta atcgagaaca aaatcgattt tgataaaaag aaaaatctgt
    33301 tgattgcttc agttatctta gtagtaggaa ttggcggact cgtctttgaa gtaggcacat
    33361 ttacattgtc ggcaatggca ttagcaactg tacttggcat cattttaaat cttatcttac
    33421 cagaaacttc acgaagcgaa gaaaactaag gaggaaacat tatgatcatc aaatcagaac
    33481 gtatcagctt aaagcattta ttgaccgttg aggcacttac tgatcaagaa gttatgggct
    33541 tgatccgcag agggcaggaa ttcaagcaag gtgctaattg gactccgcaa aagcgccagt
    33601 actttgctac aaacctcttt ttcgaaaata gtactcgcac acataaaagc ttcgatgtag
    33661 cggagaaaaa actagggcta gaagtgattg aatttgaagc aagcacaagc tctgtccaaa
    33721 aaggggaaac actatacgat acagtactga cgatgtcagc attaggcgta gacgtagcgg
    33781 ttatccgtca tggtgatgag aactattatg acgaactgat acaaagtaaa acaatccagt
    33841 gttcgattat caatggagga gacggaagcg gacagcatcc aacccaatgc ttgcttgatt
    33901 tgatgaccat ttatgaagaa tttggtcatt ttgaaggtct gaaagttgcc atcgtaggtg
    33961 atatcactca ctctcgcgta gctaaatcca atatgcagat gttaaaacgt ctaggcgcac
    34021 aagtattctt ctcaggtcct agagaatggt acgacgatga attcgaagtg tacggacatt
    34081 atatgccatt ggatgaacta ctagatcaag ttgatgtcat gatgatgctt cgggtgcaac
    34141 acgaacgcca tgatggaaaa gaaagtttct caaaagaagg ctaccatcag gaacatgggt
    34201 taacagttga gcgtgcgaag aagttgcaaa aacatgcaat cattatgcac ccagcaccag
    34261 ttaaccgtga tgtagaatta gctgattcat tagtggaagg attacagtcg cggatcgttc
    34321 agcaaatgag caatggagta ttcgtcagaa tggcaatctt agaagcagtg ctaaatggaa
    34381 aagcgtaatt ataggaggat gaaaaaatga aaacactcat taaaaacggt cagatcaata
    34441 cacgaaaaaa tatgacgaca ccagcagaaa tttggataga agatgggcga atcaaagcaa
    34501 tcggtacagg attctcagaa gccgaatttg atgaagtgtt tgatgcaaag ggacaattga
    34561 tcacacctgg tttagtggac gtccatgttc atttgagaga gccaggattt acatacaagg
    34621 agacgatcga agctgggact cgctcagctg ctcgtggcgg tttcactact gtatgcgcga
    34681 tgccgaattt aaatcctgta cctgatacgg cagaaaagct gagacaagta tatgacatca
    34741 ttagaaaaga tgcagttgtg aaggtattgc agtatgcgcc aatcacagaa aatctgcgaa
    34801 gtgagaaatt agttgatcaa gaagcactga ttgaagaagg tgcttttgct ttcacaaatg
    34861 acggtgtagg tgtccaaaca gctgggacga tgtatctggc tatgaaagaa gctgcaaaaa
    34921 acaataaagc cctagtagcc catacagaag atgaatcttt attatttggc ggcgttatgc
    34981 acgctggcaa gaaggcagaa gaacttggtc ttcccgggat cttaagcgta accgagtctt
    35041 ctcaaattgc tagagatctg ttgctagctg aagcaactgg tgttcattac catgtttgcc
    35101 atgtttctac taaagaaagt gtccgtgtaa tcagagacgc aaaaaaagca ggaatccacg
    35161 taacagcaga agtttcaccc catcatctta ttttgatcga cgaagatatt cccgaagatt
    35221 tcggcttttg gaaaatgaac ccgccgctaa gaggacggga ggacagagaa gctttgatcg
    35281 aaggcttgct tgacggtacg atcgattgca tcgctacaga ccatgccccc catggattag
    35341 aagaaaaaag ccaaagtttc atgaaatcac catttggtat cgtaggaagc gaaacagcgt
    35401 ttcaactgat ctatactcat tttgtagaaa ctggtcgatt cacgttggaa caagtgatca
    35461 attggttggc agttaaaccg gctgagattt ttggtttgaa tgcaggaacg ctaacggttg
    35521 gtgcccccgc tgatgtagca gtttttgata ttacacaaac ttgcacgatc gataaagaag
    35581 actttttatc aaaaggggag aatacacctt ttatcggctg gaaagtaaaa ggcgaaacac
    35641 aaatgacttt tgtcaacgga aaacttgtgt ggcagaaggg agaataaaag tatggaacgt
    35701 ttgcttatat tagaagatgg aacagttttc gaaggaaagg cttttggtgc agatgctagt
    35761 gtcttcggag aaatcgtttt tacaacaagt atgactggtt atcaagaaac tatcactgat
    35821 caaagtttta acggtcaaat cattacattt acctatccta tggtgggtaa ttatggggta
    35881 aatagagatg attatgaatc gatttctcca acatgcaaag gagtagtagt aaaagaacat
    35941 gcacgtgtag cttcaaactg gcgaaaccaa atgacgctag attcattttt gaaacaaaaa
    36001 ggaattcctg gaatatcagg tatcgatacg cgcgccctta ctcgcaaaat ccgtgaagtc
    36061 ggaacgatga aagctagtat cgttgatgct ggagattcct tcgaacatgc atttgatcag
    36121 ctgaaagcaa ccgttctagc aaccaatcaa gtgcagcaag tctcaactaa caaaccttat
    36181 ccaagtccag gaacaggtcg gaaagtcatt gtcattgact tcggcttgaa acatagtatt
    36241 ttacgagaat tgagtaaaag aaactgtaac ctcacagtac ttccctataa cacagatgcc
    36301 gagacgattt tagcgctatc accagacgga gtcatgctga cgaatggacc tggtgatcca
    36361 aaagatgtgc cagaagcaat cgaaatgatc aaaaaaatcc aaggaaaagt accgattttt
    36421 ggtatttgtc tcggtcacca gttatttgct ttagccaacg gtgcagatac ctataaaatg
    36481 aaattcggac atcgaggatt aaatcacccg gtacgagaag tagcgaccgg aagaattgat
    36541 tttacttctc aaaatcatgg ctatgcagtc gatgaagcca cgattgatcc agaaaaactc
    36601 atcgtaactc atgtagaagt aaatgacgga acagtagaag gagtcaaaca cagagattat
    36661 cccgctttca gtgtgcagtt tcatccagat gctgcccctg gtccgcatga tgcactacat
    36721 ttatttgatg aatttatgga aatgatggac gcaggaaagg agcagtaaac agatgccgaa
    36781 acgtacagat atcaagaaaa ttatggtgat tggatctggt ccgatcatca ttggtcaagc
    36841 cgcagaattt gactacgcag gaacacaagc ctgccttgcc ttaaaagaag aaggatatga
    36901 agtggtttta gtaaattcta atcctgcgac gatcatgacg gataaagaag tggcagatca
    36961 agtatatatc gaaccgatca cacttgaatt tgtatcaagg attcttcgaa aagagcgtcc
    37021 agatgctctc cttccaactt taggcggaca gacaggcctc aatatggcaa tggagctggc
    37081 agcatcaggt attttagaag aattgaacat agaacttcta ggaacaaagc tttctgcgat
    37141 cgatcaagca gaagatcgtg atctattcaa acagttgatg aaagaattga atcagccaat
    37201 ccccgagtct gaaatcgtca atacagtaga agaagctgta gattttgcaa ataaaatcgg
    37261 ctatcctgtc atcgttcgtc cagcctttac tttaggcgga actggtggag gtatgtgtga
    37321 aaatgaagaa gaattacgta tcgtatcaga aaatggatta agtctttccc ccgctaccca
    37381 atgtttgatt gaacgaagta ttgcaggttt taaagaaatt gaatatgaag tgatgagaga
    37441 ttcggctgat aatgcaatcg ttgtctgcaa tatggaaaat tttgacccgg tgggtatcca
    37501 tacaggtgat tctatcgtat ttgcccctag tcaaacattg tctgaccatg aatatcaaat
    37561 gcttcgtgat gcttctcttt cgattattcg agcacttaag atcgagggag gctgtaatgt
    37621 ccaactcgct cttgatccac atagttttaa ttattatgtg attgaagtca atccgcgtgt
    37681 ttctcgttca tctgcgttag caagtaaggc gactggctat ccgatcgcta agctagctgc
    37741 taaaatagcg cttggattaa cattagacga aatgaaaaat cctgttacag gaacgacttt
    37801 tgcagaattt gaacctgcat tagattatgt tgtagctaaa attcctcgct ggccgtttga
    37861 taagtttgaa aacggagaac ggcttttagg cacgcagatg aaagcaactg gtgaagtgat
    37921 ggctatcggt cggaatatcg aagagtcttt attgaaagct gtgcgttctt tagaaatcgg
    37981 tacacaccat atcgaacttc ctgagttggc agacatcacg gacgatgacc taatccaaaa
    38041 agtggttcga gcacaagatg atcgcctgtt ttatgtagct gaagctatta gaagagggta
    38101 caccatagaa gaattagcgg atttgacaaa aatcgattta ttctttttag ataaactgtt
    38161 gcatatcgta gaaatcgaac agcagttgaa acagcagccg ttggatgaca agatattgaa
    38221 aacagcgaaa caaaacggtt ttacagacaa aaaagtggcg gagctgtggg aaataaacga
    38281 agaagccgtt cgccagatga gaaaagaaaa tgatttgatt cctgtatata agatggttga
    38341 cacttgtgca gcggaattcg aatcaaaaac accttatttt tatagttcct atgaatatga
    38401 aaatgaaagt tcacgatcag aaaagccctc aattctagta ctgggatctg gtcctatccg
    38461 tatcggacaa ggggttgaat ttgactatgc gactgtgcat tctgtcaaag caatccagca
    38521 ggcaggatac gaagcaatca tcatgaacag caatcctgaa acagtttcga ctgacttttc
    38581 tatttcggat aaattatatt ttgagccatt gaccttcgaa gatgtgatga atgtgatcga
    38641 gctagaacag ccgataggag taatcgttca atttggtggt cagacagcaa tcaacttagc
    38701 cgaacctttg actgctgctg gtgtaaaaat cttagggaca acgatcgaag acttggatcg
    38761 tgcggaaaat cgtgatttat tcgagcaagc gctgaaagag ttggatattc ctcaaccttt
    38821 aggggatact gctacaagta aagaagaagc cgtggttatc gcttcgagaa ttggttatcc
    38881 agttcttgtt cgtccaagct atgtattagg cggacgtgcg atggaaatcg ttgaaaacca
    38941 gcgagattta gaagattaca tggaacatgc tgtgaaagca tctccagaac atccagtact
    39001 agtggaccgt tacttgcttg gtggtgaatg cgaagtggat gcgatttgtg acggtgaaac
    39061 agtactcatc ccagggatca tggagcatat tgagcgtgct ggtgtccatt caggggattc
    39121 aatggctgtg tatccacctc aaacattatc tgaatcgatc aagaaaacga tcgaagatta
    39181 cacgatccgc ttagcattag gtttgaattg tgtcgggatg atgaatatcc agtttgtcat
    39241 ccatgaaaat gaggtttatg tgatcgaagt caatcctcga gcaagtcgga ctgttccatt
    39301 cttaagtaag gtgacaggaa ttccaatggc acaaattgcg acgaaagcta ttttgggaga
    39361 gaaactaaag acacttggtt atgaaaacgg actttatcca gaaacaaaag aagttcatgt
    39421 taaagcacct gtcttttctt ttacgaaatt gcagaaagtt gatacttact tagggcctga
    39481 aatgaaatcg actggagaag taatgggatc tgacagacaa ttagacaaag ctttgtacaa
    39541 ggcattcgaa gcttctggat tacacttgcc tgaatatgga gccgtattat ttacgattgc
    39601 ggacgaaaca aaagaagaag cactagaatt agctaaacgt tttacagaaa ttggctatag
    39661 tctgatagga acgaaacata cagctgctta tttcgaaaaa aatggtctgg tcgttgaaac
    39721 agtagcgaaa atttctgagg aagcagcaga aaaaaatgta gtcgacttaa taagagatgg
    39781 taaaacacaa gtggttgtca atacgattga taaagatcgg ggaaatgctt ctaaagacgg
    39841 tttcatcatc cgaagagaag cagttgaaca tggtattcca ttgtttactt ctttagacac
    39901 agcagatgcg atcgttcgag tgatggaatc ccgtgctttt tcaactaacc ctatttaacg
    39961 gcgagcacat gttaagacaa aaagacgaaa aaccgttgca ggaggggaca gatgaaacaa
    40021 gaaatgatgg aaatcgttca gcaaaaacag ctggcaccaa agatttttga aatgacattg
    40081 aaaggtgatc tagtaaaaga aatgcagcaa ccaggacagt tcttgcatat tctcgtgccg
    40141 cgtgcagact tgctattacg ccgaccgatt agcttgaatc atatcgacca cgaaacaaat
    40201 acttgccgta tcatttatcg ggtggaaggt gaggggacta gagtcttctc tactctttct
    40261 gccggagacc atttagatgt catgggtcct ttaggcaatg gttttgattt gtccaatctt
    40321 catacaggag acgaagtatt tataatcggt ggaggaatcg gtgtccctcc tctatatgag
    40381 ttatcaaaac agttagtcga aaaaggaatt aagccaacgc attttttagg ttttgccaca
    40441 catgaagtcg tttattatga aaaagaattt aatcgtctag gagaaacaag aatcgctact
    40501 gacgatggaa catacggtat gcacggaaat gtcggtaatt tattgttagg aacgaagacg
    40561 gaacctacag ctgtttttgc atgtggttca aacgggttat tgaagacagt ggaacagctg
    40621 ttttcttcgc atcaaaatgt ccagttatca ttagaatccc gcatggcatg tgggataggg
    40681 gcttgctatg cttgcgtttg tcatacgccg gaagatgaaa caggaacaaa aagtgtgaaa
    40741 gtttgtgacg aaggaccgat ttttaaaata ggagaggtaa ttatatgaat gagaatcctt
    40801 tagcggtcaa acttcctggc ctagaattaa aaaatcctat catgccggca agcggctgtt
    40861 tcggttttgg caaagaatac ggaaaatact atgatttgaa tcagcttgga tcgatcatgg
    40921 tcaaggcaac gactccaaat gcccgctttg gcaatcccac gccaagagtg gcggaaacac
    40981 catctggcat gttgaatgca attggtttgc aaaatcctgg tctagacgtt gttatgcata
    41041 aacttcttcc agaattagag gagtacaatg agttacccat catcgcaaat gttgctggtg
    41101 cttgtgaaga agactatgta gaagtttgta gcaaaattgg cgaagcacca aatgtgaaag
    41161 caatcgagct gaacatttct tgcccaaatg tcaaacatgg cggaattgct tttggaacag
    41221 attctgatgt tgcttttcaa ttaacacaag cagtaaagaa agtttcttct gttcctgtct
    41281 atgtcaaatt gtccccaaat gtaacagaca tcgttccaat cgctcaggca atcgaagctg
    41341 gaggggcaga tgggtttacg atgatcaata ctcttcttgg tatgcggatt gaccttaaga
    41401 caagaaaacc gattttagcc aatcaaacag gtggactctc cggaccagca atcaagcctg
    41461 tcgctattcg tttgattcac caagtagcaa gtatatccag ccttccaatc attgggatgg
    41521 gcggcgtgca gacagtggat gatgttcttg agatgtttat ggctggagca agtgctgtag
    41581 ctatagggac cgcgaatttc accgatccgt atatctgtcc taaactaatt aaagagctcc
    41641 ctgtgcgaat gagcgaacta ggcatcgaat cgctggaaag attaatcaaa gaagtgagag
    41701 aggaacgtga acgatgaatc aactagacca acgaccaatt attgcattag atttttcaac
    41761 taggcaagag gtagaagact ttcttcgatt tttcccgaaa gaagaaaaat tgtttgtgaa
    41821 aatcggaatg gaattgttct accaagaagg acctgaaatc gtacgttatc taaaagaggc
    41881 tggtcataat gtatttttag atctgaaact tcacgatatt ccgaatacgg tcgaaaaagc
    41941 aatgcgggga ttggcaaagc ttggtgttga tctcacctgt gttcatgccg ctggcggtat
    42001 tcgtatgatg gaggcggcaa tgcgaggatt agaagagggg actccagaag gtggaaaacg
    42061 tccgctactt ctagctatca ctcagcttac ttctacaagt gaagaagaaa tgcatgccga
    42121 tcaactaatc gaagtttctt tagaaaaaag tgtgatccat tatgctagct gtgccaaaaa
    42181 agcaggatta gatggtgtgg tttcttctgc ttgggaagta gaagcgatca aagaaatggc
    42241 aggagacgaa tttgtttgct taactccggg tataagacca gaaggaacag tcgcaggaga
    42301 tcagacaaga gtagtcacac cttctcaggc aaaaaagatc ggctcaactt ttatcgttat
    42361 aggtcgacca atcactcagt caactaatcc ttataaagca tatcaaacga ttcaaacaga
    42421 atggagctaa cctaaaatga atgttgaaca aagtatcgca aaagacttat tagaaattga
    42481 agcagtattt ttaaatccaa gtaatccttt tacatgggca agtggaatca aaagcccaat
    42541 ttactgtgat aaccgaatca cgatgagcta tccaaaagtc cgaaaagaga tcgcaaaagg
    42601 attagcaagc aaaatcaaag aagcttaccc tgaagtacaa gtgattgctg gaactgcaac
    42661 agcaggaatc cctcatgccg catgggtagc ggaaatactg gatttgccaa tggtctatat
    42721 tcgaagtaag gcgaaagatc atgggaaagg taaccaaatc gaaggacgta tatttgaagg
    42781 tcagaagatg gttgtgatcg aggatttgat ttctacaggc ggaagtgtct tggaagcagc
    42841 tgaagcagca aaaagagaag gtgcggatat ccttggtgtt gcggctatct ttacgtatga
    42901 gttgccaaaa ggaaaagcaa atttcgaaaa agccgaaatc cctcttatga cgttgaccaa
    42961 ttattctgta ttgattgaag cagctttaga agatcgttat atcgatgagc aagaattaac
    43021 tctgctaaaa gaatggaaaa aagatcctga aaattggcag atttaagcgc gcttgatgaa
    43081 gatagagaaa tccgatttgt gtctccagaa tcatcaattg gaatagcaaa aatccaaaaa
    43141 ctgattgcga gaagcatctt ttcatcaggt atgaaaagaa acttctatcg tgatcagttt
    43201 ttgatttttt taaaattcat ttttctaaga ctggttagca gaaagaagag aataatctct
    43261 tctctttttt ctattatata tagattttct ctattttttg gtaagggagc tgtttcaaaa
    43321 atggtaaaga gcggaaatgt tgcgaatatc agttatttaa tgatatgata ttcggaaaaa
    43381 gaaatctcaa agggaggtaa cttttatggg gttgaatgaa tttattttag gattgaacaa
    43441 tttagagacg atcacaaggg cacctggatt ttttaaatat acagagcata cagttgcagc
    43501 acattcgtat cgtgtagcat ctattgcgca agttctagga gacattgaag aagcgaatgg
    43561 acaaccgatc gattggaaac tgctctatga aaaatcattg aatcatgact acacagagcg
    43621 ttttattggt gatatcaaaa cgccggtgaa atacgcaagc aaagagttaa gagggatgct
    43681 gcaaacagtt gaagaaaaga tgacggacga attcatcaac caagagattc cagctgagtt
    43741 ccaagaagtt tatcgccgtc ggttgttcga aggaaaagat gaaaccgtag aaggagaact
    43801 attagccatt tcagataagg ttgaccttct ttatgaatct tttgatgaaa tcatcaaaaa
    43861 taacccggaa aaagtttata aggagatgtt cattgaggca gtgactacga ttaaaagctt
    43921 tgaacatcgg ccttctgttc agtatttctt taaagagata tttccggaac tattgaacca
    43981 ggaattttat ggaaaagagg cgtttttaga aaccgtctca acgattgtaa agaaagaaga
    44041 aaaataaaaa tgatatgaga tgcaggggga agtatagttg aaaaagaata tggatgtcga
    44101 atggggctat tctggagaca aaggtccgga aaattgggcg agtttatgtg attggtttgc
    44161 gagaggtgcg gaatttccat tgcagtcgcc tattcatttg accaaggggg aagaaaccaa
    44221 aatagaagga gacacgcttt cctttcatta tcaaaagcaa cggtttactg acaaggaatt
    44281 caaaaacacg attcatttag taccttttga ccaactcagt tatgtagagt tcaagaaaga
    44341 acgctattat ttgacagata ttcatttcca cttgccttct gaacatatca tcaacggaaa
    44401 acaggaagat attgaatttc attttgttca tatgaacagc aaaaaagaga atctagttgt
    44461 gggtgtcatg taccagctaa tggtacagga aggttggctg tataatcaag aaaatgggga
    44521 aagttggaac ttagaaaaac atgagcattg ggtaaatccg gatgtgttct ttccggagca
    44581 aaaaagccat ttccattata ttggctcatt gacaactccg cctaccagcg ggccaatcca
    44641 atggtttgta atggatcatg taggaaaact gaaccaagag tttcttctcc ccttcgatgg
    44701 tcagtatgct cgaccgaaca accgaccaat ccagcccttg aatggaagag aaatttatta
    44761 tttcgaggag tttgagcaat gaatattcag cagatgaaat acgtggtcgc tgtagcaaac
    44821 aatggtagtt tcagagaagc ggcaaagaaa atgtttgtct cccagccaag tctttcagct
    44881 ggtatcaaag aattagaaac cgagttaggg atcacgctgt ttactcgaac gaatcgaggg
    44941 gcatatttaa cagaagaagg gcaagacttc ttaaatcgtg ccgagaaaat attggtccag
    45001 cttgatacat tagaaactca ctatctaacg agtgaaaaga gagacaattt ttcgatcgct
    45061 gcccagcatt atgatttctt aggtcctttg accgcacagc tactcgagga attcaaagac
    45121 gagatcaaac aatttcggat catggagacg acaacagcga gagtgatcga agaagtcaaa
    45181 gagcagcaca gtgagatcgg cattatttat atgaatgagc ataatcaagc tggtatcaga
    45241 agatatttac aacaaggaga gctaagtggc cgcagcattg gaaaattcaa aacgcatatt
    45301 tttttaaggc aaggacatcc attagctgaa cacgcagaga tcaccaaaga agaattgtta
    45361 tcttatcctc aagttcgttt tacacaggat ggaaataatt tcccgtattt ttatgaagac
    45421 cttatcgaga tccctgatca agaaacagtg atttatacga gtgatcgagg tactttgatg
    45481 aatatcgttc ttgaaactga tgcttacgct tcaggatctg gtattgtgat tggagggatt
    45541 cgcgagcact tgcggttaat ccctttggca gaaggcgaac taaatgaatt ttatatcatt
    45601 tattcggcga aacgtccgct cagtgaaatc gctcaaagat ttatcaaaga gcttactcgg
    45661 ttactggacc agcagagcta agaaaagcag atgagaacgc tgtttattga acaccgttga
    45721 tcaaaaaaga ggggttgtga cagaatttt
//
LOCUS       DACDAF010000012        44074 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.012, whole genome shotgun sequence.
ACCESSION   DACDAF010000012 DACDAF010000000
VERSION     DACDAF010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44074)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44074)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44074
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.012"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="IVZ69_000626"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="IVZ69_000626"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HAP8182739.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="IVZ69_000627"
     CDS             1011..2258
                     /locus_tag="IVZ69_000627"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HAP8182740.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="IVZ69_000628"
     CDS             2334..2678
                     /locus_tag="IVZ69_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182741.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="IVZ69_000629"
     CDS             complement(2795..3121)
                     /locus_tag="IVZ69_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182742.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3494..4695)
                     /locus_tag="IVZ69_000630"
                     /pseudo
     CDS             complement(3494..4695)
                     /locus_tag="IVZ69_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            4812..5327
                     /locus_tag="IVZ69_000631"
     CDS             4812..5327
                     /locus_tag="IVZ69_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP8182743.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5526..5972)
                     /locus_tag="IVZ69_000632"
     CDS             complement(5526..5972)
                     /locus_tag="IVZ69_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP8182744.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6019..7497)
                     /gene="msr"
                     /locus_tag="IVZ69_000633"
     CDS             complement(6019..7497)
                     /gene="msr"
                     /locus_tag="IVZ69_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP8182745.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7851..8480)
                     /locus_tag="IVZ69_000634"
     CDS             complement(7851..8480)
                     /locus_tag="IVZ69_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP8182746.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8464..8928)
                     /locus_tag="IVZ69_000635"
     CDS             complement(8464..8928)
                     /locus_tag="IVZ69_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP8182747.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9415..10683)
                     /locus_tag="IVZ69_000636"
     CDS             complement(9415..10683)
                     /locus_tag="IVZ69_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAP8182748.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10914..11651)
                     /locus_tag="IVZ69_000637"
     CDS             complement(10914..11651)
                     /locus_tag="IVZ69_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP8182749.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11718..12287)
                     /locus_tag="IVZ69_000638"
     CDS             complement(11718..12287)
                     /locus_tag="IVZ69_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAP8182750.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12415..13287
                     /locus_tag="IVZ69_000639"
     CDS             12415..13287
                     /locus_tag="IVZ69_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP8182751.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13629..14501
                     /locus_tag="IVZ69_000640"
     CDS             13629..14501
                     /locus_tag="IVZ69_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8182752.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14498..16456
                     /locus_tag="IVZ69_000641"
     CDS             14498..16456
                     /locus_tag="IVZ69_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8182753.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16707..17558)
                     /locus_tag="IVZ69_000642"
     CDS             complement(16707..17558)
                     /locus_tag="IVZ69_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP8182754.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17681..18148
                     /locus_tag="IVZ69_000643"
     CDS             17681..18148
                     /locus_tag="IVZ69_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HAP8182755.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18411..18893)
                     /locus_tag="IVZ69_000644"
     CDS             complement(18411..18893)
                     /locus_tag="IVZ69_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP8182756.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18993..19856)
                     /locus_tag="IVZ69_000645"
     CDS             complement(18993..19856)
                     /locus_tag="IVZ69_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP8182757.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            20454..21302
                     /locus_tag="IVZ69_000646"
     CDS             20454..21302
                     /locus_tag="IVZ69_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182758.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
     gene            complement(21473..21814)
                     /locus_tag="IVZ69_000647"
     CDS             complement(21473..21814)
                     /locus_tag="IVZ69_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HAP8182759.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SMEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAAEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            21900..22607
                     /locus_tag="IVZ69_000648"
     CDS             21900..22607
                     /locus_tag="IVZ69_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HAP8182760.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            22594..22917
                     /locus_tag="IVZ69_000649"
     CDS             22594..22917
                     /locus_tag="IVZ69_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP8182761.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(23006..24043)
                     /locus_tag="IVZ69_000650"
     CDS             complement(23006..24043)
                     /locus_tag="IVZ69_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP8182762.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(24490..25473)
                     /locus_tag="IVZ69_000651"
     CDS             complement(24490..25473)
                     /locus_tag="IVZ69_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HAP8182763.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            complement(25889..26659)
                     /locus_tag="IVZ69_000652"
     CDS             complement(25889..26659)
                     /locus_tag="IVZ69_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182764.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            complement(26652..27587)
                     /locus_tag="IVZ69_000653"
     CDS             complement(26652..27587)
                     /locus_tag="IVZ69_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182765.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            complement(28181..29830)
                     /locus_tag="IVZ69_000654"
     CDS             complement(28181..29830)
                     /locus_tag="IVZ69_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP8182766.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            complement(30025..30921)
                     /locus_tag="IVZ69_000655"
     CDS             complement(30025..30921)
                     /locus_tag="IVZ69_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP8182767.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            complement(30914..31594)
                     /locus_tag="IVZ69_000656"
     CDS             complement(30914..31594)
                     /locus_tag="IVZ69_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8182768.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            complement(31595..32377)
                     /locus_tag="IVZ69_000657"
     CDS             complement(31595..32377)
                     /locus_tag="IVZ69_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP8182769.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            complement(32370..33287)
                     /locus_tag="IVZ69_000658"
     CDS             complement(32370..33287)
                     /locus_tag="IVZ69_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8182770.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            complement(33290..33574)
                     /locus_tag="IVZ69_000659"
     CDS             complement(33290..33574)
                     /locus_tag="IVZ69_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8182771.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            complement(34402..35523)
                     /locus_tag="IVZ69_000660"
     CDS             complement(34402..35523)
                     /locus_tag="IVZ69_000660"
                     /inference="COORDINATES: protein motif:HMM:NF019371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HAP8182772.1"
                     /translation="MAKLKLQLEEEERVNQVSEELSEEIKDLCKKAKNKEIFSITDQI
                     KYARFKGIEISESDESIVQDILLYRTYYFKVTAYRKNFEKDINGKYIDLSFVKLADLA
                     KIDMYLRMILSRMIFELEHSLKTLIISSITNSLTEDGYKIVEDYDMYMQNKFIDSQRK
                     KGNTKTNEEILSEYTQASEKILDKVKGKFGYDFDFYNHHHDKISIWALLEVMTLGNLE
                     RFITFYFEEEHFGYLGLKTAQKLLKYVTNVRNASAHSRPLIYNIVEPYQFGRADSNLK
                     KRRPVIQLTQFATNAGLDSELIARALTNMKMNDIVATIYLHEKYVQTQKLKTTNFEAL
                     SDLLDRIKVNGKMYEKNHELVEVFHFFEKIVMEYGKLIT"
     gene            complement(35573..37189)
                     /locus_tag="IVZ69_000661"
     CDS             complement(35573..37189)
                     /locus_tag="IVZ69_000661"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002010966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAP8182773.1"
                     /translation="MSNASEITAKLWAMANKLRGTMDASEYKNYILPFMFYRYLSENQ
                     DEYLEKNGLDEYYEVTDSEEKEDYLEEISRGIGYAIAPEYTWEQLVSKIENHQIKASD
                     FQDMLDSFNLNAKRNPVAEDDFANVFSDINLGDTRLGSNTNERAKALNDVVLMVNDFT
                     FKDDSGHDILGDVYEYLIGQFAANAGKKGGEFYTPHEVSQVLAKIVTKDAKADDTQFR
                     VYDPAMGSGSLLLTVKNELPDGNKQGSVDFYGQELNTTTYNLARMNLMMHGINYRNMN
                     LKRGDTLDADWPFAEKDGMQIPLKFDAVVANPPYSAKWDIKNVDREKDTRFKGYGVAP
                     ASKADYAFVLHGLYHLDKTGTMAIVLPHGVLFRGASEGRIRKNIIDNNLLDTVIGLPA
                     NLFYGTSIPTAVLVFKGRESRRTKDILFIDASSEFVKGKNQNKLSPENIDKIIETYEK
                     REDVEKYAHVATLDEIKENDYNLNIPRYVDTFEEEEVTPLPHLAQELADVKQEIEKST
                     DKLFEMLGELHGTTDEAQEELRKFMEMLGR"
     gene            complement(37205..38419)
                     /locus_tag="IVZ69_000662"
     CDS             complement(37205..38419)
                     /locus_tag="IVZ69_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAP8182774.1"
                     /translation="MSNEITKEPEIRFDGYEGDWEERKVGEVFSERSERSGEGELISV
                     TINSGVVKASELDRKDNSSDDKSNYKKVEVGDIAYNSMRMWQGASGYSPYNGILSPAY
                     TVIIPKKDIDSKFFAYDFKRYDMIQTFKRNSQGLTSDTWNLKFPTLKSVKVMVPSIEE
                     QKQISTFFESLDTTITLHQRELDLLEQTKQTYLKKMFPKTGEDKPEIRFAGFTDAWEQ
                     RKLGEVATRVTRKNKKLESTLPLTISAQFGLVDQNTFFNKQIASKDVSGYYLLKKGEF
                     AYNKSYSNGYPWGAVKRLDKYDMGVLSTLYICFRPVDINSDFLASYYDTDRWYKEVSK
                     HAAEGARNHGLLNIAASDFFETELMIPKNNNEQEKIADFFKSLDTTITLHQRELDSLK
                     EMKKTLLQKMFV"
     gene            complement(38416..39417)
                     /locus_tag="IVZ69_000663"
     CDS             complement(38416..39417)
                     /locus_tag="IVZ69_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014184369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence RhuM family protein"
                     /protein_id="HAP8182775.1"
                     /translation="MNEIQFLIYEDSDKVEVLIREETIWATQKTISQLFDVGVPAISK
                     HLKNIFESGELDEEVVVSILENTTQHGAIDGKTQTNKVKYYNLDAIISIGYRVNSQKA
                     TKFRIWATDILKDYIQKGFKIDVERMKQGENAFGKDYFRELLETVRSIRASERRIWQQ
                     ITDVFAEISYDYDKNSEITKQFYATVQNKFHYAITGKTAAEIVFNGADKTKENMGLTT
                     WKNSPDGRILQSDVSVAKNYLSEKQIRSLERNVSSYFDYVERLLEDETLLGMEDFAKS
                     IDEFLTFNRYQILDGNGKISSKAAKRKAVDEYKEFNKHQHIVSDFDKEITKIEGELK"
     gene            complement(39424..42480)
                     /locus_tag="IVZ69_000664"
     CDS             complement(39424..42480)
                     /locus_tag="IVZ69_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002087288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HAP8182776.1"
                     /translation="MKSQSELRFEQEVVDYLTRIGGVKQWEYKAEIKTTEQLWNNFKK
                     ILEQNNQARLDEPLSATEFNQVKKIITNINTPYQAGQFLYGVNGVSEIEVDLDNGKHV
                     FLTVFDQAQVGGGNTVYQVVNQIQRPKVVDGKPNRRFDITLLINGLPIIQIELKKALH
                     NATEALNQMEQYIAEKQFSGIFSTLQILIAMTPFDIRYMANTTLQNFNRAFAFNWQDE
                     ETAHPVRSWKLFADKVLSIPMAHDLSTRYMVLDGTKNKESIKVMRPYQVYATKRVLDK
                     VRKFDFKHDEGKLGYIWHTTGSGKTITSFKTAWLASRLSNVDKVIFLVDRIALTNQTA
                     DAYRAYDPIAGFEGKTGVVSDTANISDLHRKLTKKSDKNIIVTSIQKMSRYVTRDSFQ
                     PLTENVLFIVDEAHRSTGDGTKNEGMLESIRKALPNSAWVGYTGTPKFPETREIFGDL
                     LHAYTIKEAIADKNVLGFKVEFKETIEAPADPTEEDIDDNLRGSVYDHSPEHVELVVE
                     DIFDNWKERSNNRKYNALFTVHVGGNRASTPRAMEYFDKFMEENNKRSIEDQIKVAIS
                     FSMDTSNSSHQLKTNENLHRAIQSYNRLFGTAFDMTTVKSYTEDLARRLNKTADDGNY
                     LDLVIVVDQLLTGFDAPELNTLYIDRTLKGGNLIQAYSRTNRIHDRDAKPQGNIVNYR
                     WPIQNEYEMNKSFAIYSNRDSAAEQLSLDELKKDNEESGILSKSFSKIESETKEVIQK
                     LAELTDNFIQLPPSEKAQEEVFEGLQEYNRLLNQLKQFTEDDEKNPVSVYDEPELFYD
                     RLGITEDQEVMLTTVLANELRERRAQIENIDISQVNLEMTHIHDVTINYDYLIELIAR
                     MADEVHEDKMDQAELTKNEIDVEIAKSDSDKEITKVRNFVSKIFTKEFIFDKYPAPRD
                     VEEMNQAMEQSQKDSNIKLYTEFVRTWGLDNSVKPKDLAKLISRHRVGQEDMDKQGEL
                     TAMMNDARTDYKEIAAAEVANLSWVKYRIEFRKAFYQMADETKKGE"
     gene            complement(42502..43080)
                     /locus_tag="IVZ69_000665"
     CDS             complement(42502..43080)
                     /locus_tag="IVZ69_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAP8182777.1"
                     /translation="MEMRKLSEFVTFVQGINQSRAEKQFGNQEIDYYDQASFEEDHKY
                     YNEATQEERVNYLFDQEVSLDKRDVVISNSLQRATMVSGQNVGKVLSLNFTKVEFKSD
                     LLDKRYFLYLFNNHKDIQRQKDRGLQGTGPVLRLTKQSLEQLVIPLPLIEEQRKIGGI
                     YTESLKLQSKLSIYTRLLEQFTNSMLEKSLEE"
     gene            complement(43383..43628)
                     /locus_tag="IVZ69_000666"
     CDS             complement(43383..43628)
                     /locus_tag="IVZ69_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8182778.1"
                     /translation="MLFLKEEKIIDKENVIGSNIRRIRLEKGIGQTELIRDLQLHKIA
                     ITRETLVKIEGGRQHIKLDQLRAIRDILQVSYEDLLQ"
     gene            43733..>44074
                     /locus_tag="IVZ69_000667"
     CDS             43733..>44074
                     /locus_tag="IVZ69_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182779.1"
                     /translation="MKKFAIILTCALLIGTISGCTTSETSSTSTETSTTTSEKNYPIH
                     FFPVPDGFEAYYHDKKLDVPLSETESTEKILPIEIERNQDDIKLKADLPLLNSTQIDR
                     HENIKVNIEKGA"
BASE COUNT        13105 a         9160 c         7533 g        14276 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgac cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
     3421 atatgagaag ctatttttgt ttggctgttc ttatgacttg atgcaggaca gctttttcac
     3481 aacctctgat ttcttattct tcttcatttg tagcaaaata attacggtga taaatgatac
     3541 aacatacact gataagaaca atggcacctg caaaataaaa cgcatagctt tcaccaatat
     3601 gttcaccaat cacacctgca ataaatggtg ctaaagctcc accgaaaaag cggacaaaac
     3661 tatagctgga cgaagcaacg tttcgttgca gacctggtat ttccatagca atcgtcgtca
     3721 acagtgtatt gataattcct tggaaaaatc ctgctaacac aatgctgatc ggtacaagga
     3781 ctggcataga agttccagct cctaataaca gcaaacaaat aatgaataag acaaatgctg
     3841 ctaaaattgt ccgataagtc gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag
     3901 caatagccag aagcacaccc cagccaaaaa atacaaaacc gacttctaat tcagaatagc
     3961 caatcaataa aaatggcgca tacgcaagta aagtaaagaa tccgaaatta tataacaatg
     4021 cgattagtcc aactgaacga agtttatgat tgcttaacgc tttgacacct tcccaaaggc
     4081 ctacttttct ctttggtttc tcagtttcag gtaaaagtac cgctagggct ataaaaccgc
     4141 aaaacatcaa aaatgctacc ccaaaaaatg gataacgcca tgaaccactg cccaagaccc
     4201 caccgactag agggccaaca gccattccgc agccaagtgc tgcttcatac atcatgattg
     4261 ctttttctgt gttaccaact aaaatactga cgatcgttgc taaagcagta gagacaaata
     4321 aagcattccc gacaccccag ccggcacgta acccaatcag cattccgata ttcccagata
     4381 atccgccaag accagcgaat acaacgatga taaacaatcc tgtcatcaat gttttttcaa
     4441 accgatccga ctagataaga aacctgtaaa tagcatcacc acaccagtga ctaacatgta
     4501 actagtaaat aacagggtcg tttcagctgg cgtagcgttt aactgtgcag caatcgtttt
     4561 taagattggg tctactagac ccactcccat aaaagcgatc atacaggtag ctgctacaac
     4621 tagcgctgaa cttttcccct ttgtttcttc atttgtttgt tcttgtatat ctatttgatt
     4681 ctccaatatt tccatccctt tctctctatt agcatcatac atgatttatt ttacatgtaa
     4741 atatgcacat gtaaaacgtg gaaactttac tgtgatataa taaagaaaat aagacgagag
     4801 gtaggatttt tatgaatact ttagcctata tattattatg cgtgctttta tccaaaccac
     4861 gttctgggta tgaattgaag cagctgatca caattttttg ggaagcccat cacagtcaga
     4921 tctatacaac gcttgccaag ttagaccagc agggttatgt gaccgttttg gacaaagacg
     4981 agcactctca aaaaaagatc taccacttga ctgatgaagg acgtgctctt gtagaggaat
     5041 ggatcaaaga ggaaactccc gctcctacgc aaaaagatga atttctagca aaaatctatg
     5101 ctttttcgac gctcgataaa acaacagcta ctggactgct attcactaga gaacaacagc
     5161 tgaacaaaat catgcaaaaa aatcaaaaaa aattgaatga cctctcgcta gacaagaaac
     5221 aagaatttgg acgttatgtt gtgatccagc gcagaattat gctttgtcag caggaactcc
     5281 aatggtgtca gcaagtaaga gaacaaatgc agcagttttt tgagtaaggg ataaacagaa
     5341 cctttctaga aatatctatt gaagagcaaa ttatcttcaa taaaagagca atacagttgg
     5401 aaaagaaaaa gcgatccgaa cgacaggcca aaacctatcg ttcggatcac tatttttcta
     5461 gaactgcatt caagagacta tgacaaaaag catgccaagg ccttttttca aataacagtg
     5521 ttccatcatt cattactttg aattgctttt agcacacttc ttgaaagcgg gccaacgatg
     5581 atcaactgca acggtaaagc ggcaatcaca ttcattttcc aagcattcat ataagcagag
     5641 aataattgat caggtattcc ttgttccatg atcacaccga ataaagacat acatgtcacc
     5701 attcctaaaa ccatcaagca tgaaatagtt aagatcattt ggaccttgct ttctggattt
     5761 actggtagtt taaaggcaat ttttttcgcc agcacaccga tgatgaagac atccaaaatg
     5821 aaagccacca cgaatccagg cactagacca atcaacaaac ttgataaatg aagatcttga
     5881 tgcagccata aattatacgc gctcatcccc aagaccatca aaaaacacat cattgttgta
     5941 aaaattattc cttctttttt atttgtaggc aatctgtacc actcctttaa atttgtcacg
     6001 aaaatcatcg tagcacattt aaaaatttct cgtaagtact ttttttattt tctgcccttt
     6061 tatttcataa acttcatcag ccgtacgctc gacaaagtaa gaatcatgag aagtaaacaa
     6121 aatcgttccc ggatatattt gcattagctt ctctaaagct tcgatcgttg ccatatcaat
     6181 aaaattagtc ggttcatcta acagcaacac attacttggc ttagtaaaaa gcaaagcaat
     6241 cgtcagacgg gtcgcttctc ccccacttaa tgtacataac ggtttcgtca aagtttcctg
     6301 agcaaaccct aagtgattca gcaaactacg gacaagcgat tctgaaaact ctgtttgtct
     6361 catgacaaaa cgaatgatgg attcttcaga tgtcatttga taaccctttt gctgatatac
     6421 ttgaaagctt actttcggag agagaaggat tccttctcct tgtttgcgga tatgttctaa
     6481 taaggttgtc ttacctgaac cattttcacc gacaatcgcg atttttttac ctaaagaaaa
     6541 ctgaaaatca ccatttacca gtaatgttct cccacttctt tccaattgga cattttgtcc
     6601 catgatggga tagcggctgt ggagttcaag agattttggt actggaaaac ggatttgttt
     6661 catctgctgc ggcttggttg tttctcctat tttttggagt cttctctcta atgttttcgc
     6721 attcttttgg atggcttttt gtacactgtc tttttgttta gaggaagaca accgatccgg
     6781 tctgatttgt tgctttttct ttttactgga cactttttcc aacttttccg cttgtttttt
     6841 cttttcttgg atcgattttt ccaatcgttt tttctctttc atgatcgact ctgcttctcg
     6901 tagctgagtc tttttctcca attccttttg agtgagatag gcactataat tccccgaaaa
     6961 ctctcggatt tctccgtctt ttacttccca gattttcgat gctagctcat ctagaaaata
     7021 gcgatcatga ctaacaaaaa ccagcgtacc ataataataa cgaagctctt caatcagtcg
     7081 atcaatactt tttctatcta gatgggttgt tggctcgtct agaagcatcc cttgttcata
     7141 agaagaaaga agacgtatca actcgatctt tcgttcttcc cctccgctcc atttccgctc
     7201 tgaagtttct tccagtctta actggaaatg actggctaat tccaaattta ggtcctttgc
     7261 ttcagcgaga taggttaatt gaggcaggta gttgaaggtg atctctgttt ggattttccc
     7321 atgatcggga aaaagttcac cggctattag tttgagcaaa gtcgatttac cgacaccatt
     7381 ttctcctatg atccctatac gatcttgctg atagacacga agagaatcaa tagatagttc
     7441 tagctggttg ccaaagctga cttgtagatt tgttatattt actgctaaat tttccatatg
     7501 ttttacactc ctatttcatg taaaacaaca attatcgata ctaaaaaaga gcagaaaaat
     7561 ctgtttgcaa aaaaactgca tcacatcttt tcctactctg aacgaaataa ctatgactaa
     7621 atcaccaaat ctgtcatagc tttcacctat tctactgtcg ttcgaaaaaa tggacatact
     7681 ccatccatga aattgttgtt tatacatgtc ttttgaattt atttagttgt tattcaaaag
     7741 ttcgaaacgt aatttcatcg atgcagtcat ttttccgacc tcctttttta ttaggttacc
     7801 acacacgatt caaaaaaagc aatagctact gaatagtaac tgaaaacctt ttattcgaac
     7861 gtagtgatct tttctggtgc taaacgaaca gactcgtaac cttcttctac cgcttttcct
     7921 attgataaaa taataactgg aacataacgg tctttatcca aaccaaatgc ctctgccaac
     7981 tgatctgctt cgaatccacc aattggattt gtttcatagc catgatcacg cgcaactaac
     8041 atgaattgca tagccgctaa gctagaatcg actttgacta catcgttcat ttcttctctt
     8101 gaaaaactct tgtaataagg aatgatcgca gctaattgtt gatctctgac ttcttttggc
     8161 atcttccctg attcgtaagc ttggttatag atttcttcgc catattcgta acattgcata
     8221 tcgccaaaaa tcatgaccat tgcagaagaa gtatcatttt gtctcgtatt gaaacggatc
     8281 aaaggacgca agatttcttt tgcttcctcg ctttcagcga ccacaaagcg ccatggttgc
     8341 atattgacag aagaaggtgc agtcgtcgct tctttgatca tttccagcat ttcttcgtgt
     8401 gggattttgt atgtttcatc atatacgcga acggatcttc taccagtcat aattgttgaa
     8461 aaatcatttt tttgttccat tattattaac ctctttcgtt tctgttgtta tattgcaaag
     8521 ttgggtattc aatttatcta aaagtgttag aaattgtttc atttctacat cgctgaaagc
     8581 cggggatagc acggaacctg tatctttatg gtccatttca caatgctcga ttttcttctg
     8641 ggctttttct gttagcgcta catacacttc ccggttgttc tgaggatttc tctgacgcga
     8701 aacatagcca tttgcttcca ataccttcag atgacgagta actgctcctt gatcaatctg
     8761 caacttttct tgcaaactgc tttgtagcaa tggattttct tctttcagtc tcatcatgat
     8821 ctcgtatcta gtaagactta taccgatatt ttcttcaaag atctggacga ttttttgatc
     8881 ggctaatttg atttgatata aaaggtgact aatctcttct aaagacataa tttcctcctt
     8941 tctaataatt gactcgtcaa cgattgactt gtcaataata gaataaaaaa agaaaaaagt
     9001 caaagaatca gctgtgtaat aaaaaaaacg ctctcaatag aaaagtatag agaaaagaaa
     9061 ttttttgtag aatgaacgga aaaaatgata aagaaagcac aacgctaaaa ccaagattat
     9121 tgattcttat caaactatag aagatagctc ttctgcagta gaaaatttta caccgccaaa
     9181 aatttccgaa atcgcctttt gcaagaatcc cgtcgaatat tagaaattgg atcagtatgc
     9241 ttaaacagta ataaaaaagt tatgacaaga tgttgtcaca accttttttg agtaaacggt
     9301 gttcaaaaac ttgcatctgc ggtaataagt tcaaccaaac aaaaaacatg aaaatctgtt
     9361 tttgtttggc tgttcttact acttgatgca gggcagcttt ttcactacct ctttttaata
     9421 accataaaat cctattcctt catatctcca gcccatcggt gttagccaat ctctttcctt
     9481 agcactcaag gtatagtgat gggtaccagt tttttcattt ggattaaata gtcgataaat
     9541 tggcttggaa ccaccagaat aaaaacttag accttcataa cgccaaccga tttttgttaa
     9601 agagttgatc tcagattgtg ccattgtgta atgatggtct ccactgtaag gattgtataa
     9661 acggtagaca ggttgtccgc tgtttggtgc ttgccaagca atcccttcat attcccagcc
     9721 tacagttggc agataatttt tttctccggc attcaatgta tataaatgtt ctcctgtatg
     9781 acggttatac agacgataca tcggagaagt tgaagttggt gctgtatcat actgtgtcag
     9841 attataggtt tcgattacat tgttcaatgt agaaccataa ttaggcgcag tggcataacg
     9901 acctgttagc caagccgtag catctttgta agagttcgta ttgcttttcc atgcaccgga
     9961 atagtagtaa acgcctggct gaaaagaagt cgtcttcaat accgttacgt tatcttgcaa
    10021 tgattctttg tacgaaggat attttctaaa agcggcattc accgtaatcc attgcccatt
    10081 cacatattcc gaagtaggca tcgtaacaga ttggccatta tagcttcctt taatcccaaa
    10141 tagattgtaa ttaggggcag aagccaaagt actgttcccc cagccacttt caacgatggc
    10201 ttgagcaatc atgactgatg catataagtc attggcactt gccaaacttt gtgcagttga
    10261 ggcaatacta tcaatgaacg cttgttgaga attagcagat gagcgagcat aaaaagcata
    10321 gccagtatag ttttcgaatt cagacaaatc tgcttgatgg gtatgtgtca atgtttgccc
    10381 atctgtcaat tggttcgtga tttcttctgc attctctgga ttgttctgag cttctgctga
    10441 tgtactgtct tcggtttgtg tttgttctgt tgtttcagtt gttggttctt cggttgaaat
    10501 tgtattttct gagacagtag ctgactgcaa agtactctct gtatcgtttt caattcctgt
    10561 ttctgaagaa ctcgatgtct gagttgcgac agtttctgtc gattcttcag ctagcactgt
    10621 tgtgttggca actgctagat ttcctaaaag aataacgcta aataataaat tctttgcttt
    10681 catctttttt ctcctttgaa ttatgaaact tttcctaaat aacagtgtaa ctaaaaaagt
    10741 aaaagcaagt caatgtccat atttaaataa catttgtttc tttttgataa atttgctttt
    10801 tctacataaa aagacgtaaa tgaagaatat tcttctccat tcacgcctta aattgatggt
    10861 cgtttgaata actatttaac aagtaattct ctttggatat tatccgttat ggattatact
    10921 tcctgtgtcg tcggacggat aatcatgtta ctgacagaca tccggtctgg cgtttctatc
    10981 gcaaatgcta cagcagaagc tatatcttcg gaggtcaatc cccattcttt ttgcgcttca
    11041 tgaagttcaa gagcagcctt tttgtcgctg atggtttgat ataattcagt ttgaacagct
    11101 cctggagaga tgatcgtaga tttgatgtta ttttgccgtt gctcttgacg taatccttcc
    11161 atgattgcac ggacagcaaa ttttgttccg caataaacgg cggaatcagg ataaacaaca
    11221 tgtcccgcca cagaatcagt tgaaatgata tgcccagatt tttgtttttc catgattgga
    11281 agtacggcgg aaattccatt taacacaccc atgatgttga tatcaagcat attttgccat
    11341 tcatcacggt gaccttcaac taatggagcg gttggcatga ttcctgcatt attgtacaat
    11401 acatcgattc gaccgaactt ttccatcgct aaatcgataa ctgcttggac ttgtgcaaaa
    11461 tctcttacat ctgctgtttg aatatatagc tcagcttctg gtaaagattc ttttattgct
    11521 tttaggcgat cttctcggcg tgcagctata actagtttag cccctttttc tgctaatagc
    11581 ttcgttgttg cttcaccgat tccgcttgaa gcgcccatga tgacaatcac tttttctgat
    11641 aaatcattca ttctattctc ctcctgtttt gaaaaatctc ttgcttatac tcactatctc
    11701 ttatttcatc ttactgttca aataatccgt tcgacaggtt tgacgatttt ggcagggatt
    11761 cctgcaacga tggtattgtc tgggacatct ttcgtaacag ttgcattcgc tgcaacaatg
    11821 gcattctcgc caatcgttac gcctggcaga atagttgctc ctgctccgat ccaagcattt
    11881 ttcttgatgt ggattggctt tactgacaag cctcttcgtt cttttggatc ggttagatgg
    11941 ttcaccgtga tgaggttgac acgaggacca atcaatactg aatcttctaa acagatgcca
    12001 cctaagtcaa cgaacatcac ttgacgattg ataaagacat ttttccctat actaatatgt
    12061 ttgccgaaat ctgtataaaa aggcagcaga acagtcaccg tatcatctac tttgtcacta
    12121 atgatatttt ctagccgttt gcggatatct gctggttcat ggtacccagt attcagcgct
    12181 gctaaaggct cttcgttttc agcttggatc tgatggatca cttcaaagag cggatccgtt
    12241 actcgaatct ctttattgac gatttgtttt tcgatgaggc ttgtcatttt gctccctcct
    12301 tttatcctta ctttataacg gacggcttat catgtctaat acttataaaa catacttaac
    12361 tattcctttt aactatactt agtggtatgc ttttttaaaa acaggaggga aaaaatggat
    12421 attcgtatac tgacgtattt tttagcagta gctagagaaa aaaatatcag ccgagcagca
    12481 aaatctctgc atatcacgca acctactctc tcaaaacaac tgaaagattt agaagaagaa
    12541 cttggtgtga cacttttcac tcggggctcc cgagagatac agttgacgga ttctggtcga
    12601 tatctttatt caaaaggaaa agaaatcttg tcgttggtag aaaaaacggc gaacaattta
    12661 acaaatgacg caatcatctc tggagaaatc tacattggcg gaggcgaaac taaagcaatc
    12721 tctttcattt ctgatagcct tcattcgttg atcaaggcgc atcctgatat ccagtttcat
    12781 ttatatagcg ggaatgcaga tgatatcata gacaaactgg atagcggatt acttgatttt
    12841 ggactcgtaa tcgaaccgac aaacaaacaa aaataccagt catttcgact gccagcccaa
    12901 gatcgttggg gacttttgat acatcgaaat catcctttag caaagcaaac cgtcatccat
    12961 ccgcaggaac tgaaaactgt tcctttgatc atttcccggc aaacgtcagt ggacagtcaa
    13021 ctagctgaat ggctaggttt cagcatagat cagttatcga tcgtcggaac atataactta
    13081 ttgtacaatg cttctttgat ggtcgataac gggacttttg gtgcattagc tctagatggg
    13141 atcatcaata cttatgggac ggaaaaaata ttcatcccac tcgatccgcc attacaagct
    13201 tcactgaatc tcatttggaa aaaagaccag cctctttctc ctgctgctcg taaattttta
    13261 gatgtcctaa cggagaaata cagttaagta gagttttttt ccttcgcttt cagcttttta
    13321 acaacgaata agataagcaa aagatccaac gattaaataa cataagtttc ttaatttatt
    13381 tcttcctttt atttctgata attccagtaa attactataa ttataaaaaa agaattgaca
    13441 aaacataact gtctatataa aattgattac gttaacaata attcgtttca tgtgactaga
    13501 tcatactagg catgaaaaat ctctgaggaa catggtttcc ctaggaggtt tttcgtgtct
    13561 atttttgttt ggccgcaatc aactggtcta gcaaacgtga aaaccaaatc ttcaaaaagg
    13621 gtgcgcgcat gaaaatcaaa aagatcttta atcaaaatgc agtattggta gatgacggtg
    13681 gacaggaaaa agtagctatt ggaaaaggga ttggatttga cagaaaaaga aatgatttga
    13741 tttttgatcg tgatgtcgaa cggatatttg tcatggaacc agaaggtcaa atcaagttgc
    13801 aaaatttact taatcagatt gatgaacgct ttttatttgc agcagaaacg atcattgatc
    13861 atgcggaaac tgttttgatg gaaaagttga atgaacatgt attgatcgct ttgaccgacc
    13921 acattgcttt ttctgcggag aacattaata acggtatcgt catccgcaac aaacttttaa
    13981 gagaaatcga agtgctttac agtgatgaat tcagtattgc tcaatgggca gtagagtatc
    14041 tgacaaaaga gcttgggatt ccatatactt atgacgaagc aggatatatc gcaatccata
    14101 ttcacagcgg acgaagcggt cggaacaata accatcgcag tatccgtgaa gtgacgattg
    14161 tatctgacat catccattta gtggaatcag aattggaaac agatatccat tcagaaccat
    14221 tttcactgaa ttattcaaga ctggtgaatc atttacgact gcttctacaa cgaacccatg
    14281 cgcaacaata tgctgtttta gacacggaaa tcgtagaaat ggtcaaacga aaatacccag
    14341 aaagctataa gatttctaaa aaaatccgtg tgttgctgac caaagaatac cagctcgcga
    14401 tcacgaaaga agaactgggt tacttggcca tccatatcga gcgtttaaga agcgcaatcg
    14461 tacaaacaaa tgttaacaat catgaggagg aaaaaaattg aaagcatatc tacaacgaat
    14521 gggacgttcc cttcaacttc cagttgcggt cttacctgct gctgctttac tagtagggat
    14581 cggaaactgg tgggcatctt atagtaacga cattgtcgct cattttttac aagctggcgg
    14641 taacgcagtt ttaggtcaat tacctttgct gtttgccgtt gggttagcac tagggatgtc
    14701 agtggacaaa tcaggtgctg ctgccttggc aggtttggtc gcatttgaag ttccagtaaa
    14761 tgttttaaaa actgattcag tagctacttt attgaatatc aaaccagaat cagttgatcc
    14821 atcttttgct cagatcagta acgtatttat tggtattatt gccggattga ttgcggcagc
    14881 tctttataat cgtttccacg aagcaaaatt accgatggct ttatctttct ttagcggcaa
    14941 gcgtctagtg ccaatcttgg ctgcctttgt catgttgctg atcagtgcag tgctactgct
    15001 cgtatggcct ccggtttact ctgctttagt ttcttttgct aaattcattt tgagtttagg
    15061 ctggggtggt gcaggtcttt atggcttctt caaccgttta ctgatcccta caggattgca
    15121 tcaagcaatg aactccgtgt tctggtttga cgtagcagga atcaatgata ttggtaaatt
    15181 tttggcttct gaaggaacaa aaggcgtaac aggaatgtat caagctggat ttttcccaat
    15241 catgatgttc gggcttccag caggagcata tgctatttac agaaatgcac gtccagaaaa
    15301 caaagcaaaa acagcttcct tgatgctagc agcagctttt gcttcattct ttactggtgt
    15361 gacagaacca cttgaatttt catttatgtt cgttgcttgg ccattatatg tcttgcatgc
    15421 aattttcact gggatttctt tagcagtgag tgcattcttc cattggacag caggatttgc
    15481 ctttagtgcc ggatttgtcg attacttcct atctttgaaa aatccgattg cgaatcagcc
    15541 attgatgttg atcgtccaag gattagtaac agcagtgatt tactactttg gctttaactt
    15601 tgctatcaaa aaattccatc tgatgactcc tggccgcgag gaagcagatc tttcagatga
    15661 cgatactgca acgactaatt cagacaataa atatgcggca caagcaagca aaatctacgc
    15721 tgcattaggc ggagccgaca atgtaacttc gatcgataac tgtactacac gccttcgttt
    15781 gcaagtcaaa gatacaggcc tgatcgatca aaataaaatc aaagccactg gcgtacctgg
    15841 tatgaagatc atcgacggaa aaaatgcgca agtcatcgta ggtacagaag tacaattcgt
    15901 tgcagatgag atggcaaaac tacatggtgg tgctgcagca cgacctgcac aaacaaacac
    15961 cgtggttaaa acagaaacat ttgccggtga aacgatcgaa caagatattt acgctatcgc
    16021 aaatgggaaa ctgattccaa tcactgaagt ttcagatgat gtattcgcgg aaaaaatgat
    16081 gggtgacggc tatgctgtat taccagaaaa tggagaaatc ttctctccaa tcgctggtac
    16141 gatcacaaac attttcccaa cgaaacatgc tgtcggaatc caaacagatg ctggtatcga
    16201 agtcttgctt catatgggca tcaacactgt tgacttaaaa ggcgaaccat tcactttata
    16261 tgtagaagaa ggtcaaaaag tcgcaagagg tcaattgatt gctttagttg atcttgccgc
    16321 tattcaatct gcaggcaaaa acacggatat ggtcgttgta ttcacaaatg gcgacaaagt
    16381 ccaaagctta gaaatcgaac ccgcacgtga tgtaaaagca aatgataaaa tcggctctgt
    16441 ttccaacaaa gcctgagcca tcgtcttccc cagacttttt tatcgataaa caaacaggag
    16501 ctgagacaaa aatcttgtct cagctccttt ttccgaataa aaacggcgtt ctcctgccaa
    16561 ctccgcggta ataagtccag ctaaacgaaa catatgaaga gctatttttt atttgactct
    16621 tcttattact tgatgcagaa cagctttttc acaaaatttt tcttcatact caaaactaat
    16681 cggctttttc acaacctctt tatacattat tcctgatcca atatttcttt taatgctgct
    16741 tcaagagaag ttaatggttt tcccaatact ttttctaaat catcagagga aatagctaac
    16801 tgatcctttt taatatcatg ttggatcgct aaaaacatgt cagctgcttc ttgagggaat
    16861 ccggcttctt ttagattttc gacaaacgct gcatcacttg cttcaataat ttctaactct
    16921 ttacctgtcg cacgctctaa tgccttggct aattcttcat agtcagttag attgccggat
    16981 aattctaaga tttctggaga gtcactttct actagtactt ttgctgcagc ttctgcatat
    17041 tcacgtttca atgcccaacc tgtttttcca tttcctgcag cataaacgaa ttgaccagtt
    17101 tttaaagcct gcccaatgat aggtaattca ttctctacat accaattatt ccgtaaaaat
    17161 gtatgggaaa tacctgaatc cttaatcatt ttttcagtga attggtgatc tggcgctaat
    17221 acactgatcg agtgatcggc atctgcaaaa cttgtataag cgatataaga taccccagct
    17281 gcttgtgctg ccttcactac attcttatgt tcggcttgac gatttcctgg aacgccagag
    17341 acaaaaagca atcgatctat tcctttcaac gcttctttca ttgagtctaa atcatcataa
    17401 tcaccaatac gtatattaaa tccagcttct ttcagtgctt ctcctttttc ttcactacgt
    17461 actagtacat agatttcatt ttgtggaacc atctttttta agaattccag cgcataacca
    17521 ccaaaacctc cagttgctcc tgttactaaa taatgcatat ttgccactcc ctattctttt
    17581 tatttgttaa gatttacagc tgtacattta taaattacac ctttatcata aagagtgtgg
    17641 taagataagt caagcaaaaa aaatgaaagg atgacaactg atgaagtatt ctctgcaatt
    17701 tagtgatgca atccatgtac ttgcctatat tgaaatgttt caagataccc gatcactttc
    17761 tagtgagatg attgccagta gtatcgaaac aaatgcagca aatgtacgta aaatcatgag
    17821 tcagctcaaa aaatccggtt tgatctttac aaaaaccgga aaaccgcagc cttcccttgc
    17881 caaaagtcca gatcagattt ctttactaga tgtctatcgc agcatcgaag gtaatacaca
    17941 gcttatccaa gtcgatccaa aaacaaatcc aaattgcgtc gttggtgcga atatccaaga
    18001 agctttagaa gaaagctacg ctcggctgca gaaaaaggca gaagaagaaa tggctaagat
    18061 cacacttgat agtctgatac ataaaatagc cgttttggaa aaagaaaaaa gaccagaaaa
    18121 cacaggcctc gtagagagat ttttataatt ctctctactg tgcctgcatt tttctgatcg
    18181 gaatcgtcta cataaattct tttattctcc gggggacaaa agccttgtca tgcccctttt
    18241 tcctctctaa tgctcaggtc aaagcgctga agtcatgacg tcttgataaa cggtgttcaa
    18301 gtagctgacc ctcggcatta gttctgaaaa atgcaaaata tggaaagcta tttcccattt
    18361 ttcctctcta atgctcaggt caaagcgcta ctttcacgac ctctatatta tcatggttta
    18421 ttgactaccg gtatccagat ttctcccata tatttcccgt tggtaactcc catttcgact
    18481 acagcatttg gacccccaac ataggcgtaa tcttctactt ctcttaaaac atgcccaaag
    18541 gccgtattcg tcaaatcatt tcttaattct tcaggcgatt ctgctaaagc gcttacaaca
    18601 agatacgttc cttttgggaa tgggatgatt cgcgtagtgt ttggaacatc ctgactcgtt
    18661 tgaacaccga catagtacat cattttcccg ttatagggtt cgttgactgt aaagaaataa
    18721 tgattttcag cagcttgttt caatgcatct attgttccat taccgataac tttttgctca
    18781 aatgcttgtt tctctgcagc caaaccgaca aaatccgtat tgctactctt caattccaca
    18841 ccaatacccg tcaccgtaaa atctggtttt tcttcgatcc tatactttgc catttctccc
    18901 accctttcta ttatattaag ttcatcttac ataaaattaa agggaaatga cacgattacg
    18961 ctcttttttc tagggatatt tttatttttt aactattttt ttgctttcac tgcaatccaa
    19021 atctcactgt aaacattact gaaatcctct ccccattttg taaaagagat ctcgggagct
    19081 tcgactaacc cataatctga agaaggaagc cattctgcat agattttccc ccaagtatct
    19141 tgtaaagttt ggggaaatgg ccctttatta ggaaaaatgg cccaagtgtg ttcttctata
    19201 gcaagcattt ctaaatcagc gtacggattt tcttttgtcg tagcaaagcc aatcatgtgc
    19261 atcaaactgc ccttttcttc caagcggtct ccatcaaatc cataagaaac gttgattact
    19321 tgatttggat ataaatctcc taacttatgc atctcttccc tttgagtctc cgtgatcgtc
    19381 tgcgctaact tttgtatttc ttgattgact ccttcaaatt tgacaggaac ttttttcgcc
    19441 acacctgcca cataaaactg ttctttcttt tcgatacgaa attccatcga ttttcctcct
    19501 ctgacatcaa taaaaaatgt caagcgtgga aaagattttt gtatgccgta tctactgatt
    19561 tctgaaggca gatatcctga ccaatcacga aaagctcttg aaaaaccttc gactgtttca
    19621 tatccatatc taaacgccgt ttctgtcact cttgatccat ctagaagatc gcgattagcc
    19681 aaagccaatc tacggttttt gatatagtcc attagcgaca tccctgcaat aaacgtaaag
    19741 atgcgtttta attgatattc agagattcct gtattttcgg ctattatttt ataggaaagt
    19801 ccttctgtca aatgttcttc gatgtaatcg atcaattggt tcagatcttt aagcatattt
    19861 atcttcctcc ttgattgcct ttttatcata ttatcaaaga aagtcaatta cttgatgaat
    19921 caggaaccaa tttagtcaga tgtagaaaat gttgtatgga tctaaagaaa attctcaagc
    19981 agcgtttcgt aacggataat tggtattatc tgcctatcta tgttttacct ttagaaaaat
    20041 aaattttggg gaagacagat tctaagtaaa caaagcggta aaaatatctt ttattccctt
    20101 agttaatccg cttactacct actgtacaaa gcaaattgtt gttcaaactg ctgatcagaa
    20161 cgctgcttgg atttttcttt gcgatacatc atacctcttt tatcaattgg aacaattatt
    20221 tatttctaac aaaatcactt catttttgtc agataaataa aaaacaaaaa aagttccatc
    20281 tttaaaacac gctattcttt tactttttct cacattctct aagaaaagaa aaggagaatg
    20341 aatttttgac aattcgagca aaagtgatta tcaaatatgt aaaatcagct acttttttct
    20401 taaacgtttc tttatactaa atataaataa gtgtttcatg aaaggagaac tagatgaata
    20461 attggcttga gtattttcct gaaaacgttt tggaacgcgg ttacagctat catctgcacg
    20521 gttttgtccg tcatttgaac tatacaagca agtacttgtc cgcaacagtt tctggcacgg
    20581 aagattataa ggtagtgatc acttgggatg aaaagaccaa catgacttgt gattgtctat
    20641 atgccataga aggaaaaaaa tgcaaacaca tggctgctgt cttattcgct tacgaagaac
    20701 gtccaataaa aaaatccaac tactcacttt ccgaactctc gtcccttgtt tcctccgcta
    20761 gttcctctct tgtacgggag cttttaacag agattcttat agaacatccg cactttatcg
    20821 aacgcttcaa agttaagatg ccatttcatg caataaatta ttcagataaa ttaacaacta
    20881 tcatccataa atacgatcat attatcaaga aaaacaaaaa caggaaaaca gcgaagttca
    20941 tcatggagat gcgaaagttc atccaagaag cagttgaatc gcttattcag caaaatgcct
    21001 atcttcccgc attcgaattg atcaatgaag tgattgctac tctcgaaaca ttctattggg
    21061 agcctgagga tgaacgaacc cttcttctga tagaggactg ttattattta tggaaagaat
    21121 tattagcaga agcacctcat gcagaaaaaa ggcaaatgtt ctcttggttc gtctgccaag
    21181 tcgatcatac tgacgcctct tattcaaaac gctactctat aaaaatcctg aaagaagact
    21241 ttcgggaaaa agaattttct aaccaaaaga aaaaaataga taaaaaacta aagaaacggt
    21301 aaagaaagac gatttcaatg aaaaatagca agtaaacgat aacaaccatc ctaaatccac
    21361 aagaaataca gcagaccttg ctttaaaaac acgaatcatg caaaggatga agtaaagaag
    21421 acttaacgcg tacccaatat tagtcatttg actattaggt acgcgttttg ttttataagt
    21481 catgacaaat ttccttcgtt gctggataga ttttccggca ttgttgatag attttatgat
    21541 acttttctac attttgtaag agaggttccg ctgcatctgt atattggata aaattctgac
    21601 aacaactttc aggtgtgtcg aaccacccta accctagtgc agcaatcatt gttgcgccta
    21661 atgcaggtcc ttcctccata cttaaacaat agaccgttgc atcgaaaata tcagcttgga
    21721 tttgtagcca tgcaagattt ttcgcgcctc ctcccaccga aacaatacgt gtaaatctgc
    21781 gacccgctag ttctttacgt ttcaatccca ccattgacaa atgctcatta aaaatttaga
    21841 atattcacaa gtttaacgac aattatgaaa atttatgtcg tgctaaagga gttttgttat
    21901 tggatgaaaa gttagatata aaaactgcga tcaaagacac gttacctacc gttttcggtt
    21961 atatcggtat tggacttgca tttggtatcg ttgggaaagc tgccggattt catccactag
    22021 tcgtcacgtt gatgtccctg ctggtctatg ctggttctgc ccaatttatc acagtcagca
    22081 tgcttgctag tcacagccca ttgctttcca tcgttttctc gacctttcta gtcaattccc
    22141 gaatgattct gatgagtatg acgattgctc cttatttcaa gaaaaatcgg ctgcttcaaa
    22201 atctgctgat tggcacattg ctgacagatg aaagtttcgc actgggaatg aataaattga
    22261 actatactgg acaaaagtta aactttcgtt ggatgaatac agctaattgg atttcttatt
    22321 tgacgtgggt gggttcttct cttgttggcg cacttttagg gaattttatt actgatccga
    22381 aaaagtttgg tttggatttc gccatcgtcg ctatgtttat cgggttactt tatcttcaag
    22441 tcatttctga tagaaacacc tctaaacgat tacagttgat cctgattggt ctcactttga
    22501 ttctggtata tgtcggactg atttttatcc caagcaactt agtgattgta gttgtaacac
    22561 tgattgggtg cggattgggg gtgtggatca aacatgcctt cttttgagtt tacattgctg
    22621 actattttag gttgtacttt agcaacttgg ctttctaggg tcctaccatt tgtcttactg
    22681 aaaaaattcg atttaccgca accgttgctt gagtatttaa gttttgtccc gatcgtcatt
    22741 atgtctgctt tatggttcag cagtctattt acccaaaata tcggacatct gccgcagatc
    22801 aatctcgaaa atgctttggc ttcagttcct acacttttag ctgctattct ttcaaaaagc
    22861 ttattggtga tcgtcttggc aggaattctt tccctttcgt tgattcgctt attataaata
    22921 aaaaaacaag agcttatggc aaattactgt catgcgctct tgtttttatc aaagtcaaat
    22981 aagaaaaaaa tcggcgtatt cttgcttatc cgttgaacgg accactaaca acgacttttc
    23041 ctaacatatg tcctgtttct acgtctttgg ttgcttgttt caagttcttc gcattcatcc
    23101 catctgaata gaccttgctc aatgtactgc ggataatccc ttcatttgct aaagcagcaa
    23161 tgtgcgctaa agcttctcct tgcgtttcga tttcatagtt atagtctgtt ttagcgaaca
    23221 tatactccca gtcgaagctg atagattggt ttttccaaac acctatatct aacggctctt
    23281 tgatccctac gatcgttccc acatgtccaa atggtcggac aaggtgcttg atttgatcaa
    23341 agtagcgggt aatatcgaat aatacagcga catactctac ttgatcgatt cctaattcac
    23401 gaaaactttt acttaagtcg tgatgataat cgattggata gtctacacct gtttttttca
    23461 gccattcaaa attcttcgga cttgcagtcg cgtagacttc taggccagcc caatgcgcta
    23521 gttgattcaa aatcgaaccg acgcccccgg atccgttgat cactaagatt tttttcccgc
    23581 gattggcatt ttcttctgga gttagaccaa atttttcaaa taacaattca taagcggtca
    23641 atgaggtcaa cggcaaggct gcagcttctt catctgaaag attttttggt gcaagagcga
    23701 caatacgttc gtcaactagt tggtattctt gattgcttcc tgctcttgtt gttgtacctg
    23761 cgtaaaaaac gcgatcgccg acagaaaatt tttgcacttc gtcacctaca gcaacaactt
    23821 tcccgactcc atcaaaacct aagatacgta aagcatttct tatcccgtta tcttggcgaa
    23881 gtttcgtatc gacaggatta acagatactg cgttgacttt taccagaaga tcccgtgaac
    23941 tgggtacagg tatctgttct ttttcatcaa taaagctttt tggatcatcg atcggcaacc
    24001 cttcataaaa accgactacc ttcattaatt ccttttctga catacgaatt cctccttagc
    24061 ttcatcaagt tggagcatcc atacagtgtt catttcaata tatatagtat gctatttgtt
    24121 ccaccttttt tattcatcat aattattctc ttacttaaag taaactattt gcactttttt
    24181 ggttaaaaaa gaggttgcga caagactttt gtcacaacct cttataaacg gtgttctcct
    24241 accaactctt cggtcacaag tcaaaatatt catcaaacat gagaagctgt tttttgaaat
    24301 tgctccttgt gactcagagt taaacggcag gctcacaacc tctgatataa acggtgttca
    24361 atcaactgac cctcggtatt agctcaaaaa acgacaaaat atgaagagct atttttgttt
    24421 ggctgttctt attacttgat acaggacagc tttttcacga cctctaattc acggtgttca
    24481 agcaagaaat cattgttcac tgaaaagcgt tggatgttct ttttcaaagg tctctaagat
    24541 ctctcgtact tcatcagtag atttcgtatt catcaactga actcgcaagt catttgctcc
    24601 tggaaatcct ttgatataga ttttaaagaa acgatgtagt cctgtgatgg aacgcgggat
    24661 gatttctgaa taatgatctt gcagatctag ttgcagacga agtagtccga tcagttcttt
    24721 ttctgtatgt tccctcgggt ctttttcaaa tgcataagga ttcttgaaaa tccctcggcc
    24781 aatcatgatg ccatcaacgc catatttctc ggccaattct tctcctgtct ggcgatcggg
    24841 gatatctcca ttgatcgtga ttagtgtttg tggagcgatt tggtcacgta aagcaatgat
    24901 tttaggaatg acttcccaat gtgcatctac tttactcatc tctttacgcg tacgcaaatg
    24961 gacagaaaga ttggctatat cttgatgaag taggtgactg atccattctt ccatctcaga
    25021 catttccgta tagccgatac gcgtcttgac gctgacaggc aaaccgccag ctttagctgc
    25081 ttcaatcaat tgtgccgcta cttctggacg aaggatcaag ccactgcctt ttccacgttc
    25141 tgctacatta gggactgggc agcccatgtt gatatcgatt ccttggaagc ccatttctgc
    25201 catagcaatg ctcatttctc taaaaaattc tggcttgtct ccccaaatat gggcaaccat
    25261 cggctgttca tcttctgtaa atgttaatct tcctcgtaca ctgtcttttc catctggatg
    25321 acagaaactg tctgagtttg taaactcagt aaagaagaca tccggtgctg ctgcatgctt
    25381 tacgacatgg cgaaatacaa catctgttac atcttccatt ggtgctaaaa caaaaaaagg
    25441 ctttggcagc tctttccaaa aattagtagt catttatttg ttactctcca ttctatcaag
    25501 cagtgaagtc gcaatctttc tcaaaaacat tgtcattata ctaggaaaca aaaaaagaag
    25561 caaagtgaac agcttaaaag atgtttctga ttgagcaaaa aaaagactgt gacaaaaatc
    25621 ttatcacagt ccattttccg gaataaatgg tgttcaaaag cttgcatttg cggtaataag
    25681 tccaaccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat tacttgatgc
    25741 agaacagctt tttcacaacc tctccactaa acggtgttca atcagctgac cctcggtatt
    25801 cgctcaaaaa acaacaaaat atgaggaact attttcccgt ttgtttctct aatactcagg
    25861 tcaaaacgct gatttcacaa cctcttttct aacttctcaa tcctcttcct ttattgatca
    25921 aataccaagt aacggcgtac aaaacaacga tgaataacac aagtacgatc atcgatgttg
    25981 ctactggcac atcgatcgtt ccaaggaatc cgtaacggaa accggagatc atataaacga
    26041 tcggattgac ttttgaaaca gcttgccaaa agggcggtaa catagagatg gcatagaaaa
    26101 cgccacctag ataagttaac ggctgcaaga caaatgtagg cacgatcgat acatcatcat
    26161 aagactgagc aaaaatcccg ttgagcagtc ctgctaatga aaacaagatt gccgtcatca
    26221 ataatgtaat gatgaccatg aaccatgaat acacatgaag tggtacaaag aacaaggaaa
    26281 tgatcgttac gagagagccg acgagaatac tgcgacccac accaccaatc acaaagcccc
    26341 aaataatcac atgcgtagga acaggtgcta ccaagatttc ttcgatattt ttctgaaatt
    26401 tttgagagaa gaaggacgaa gaaacattgg catacgaact agtgatagca gacatcataa
    26461 tcaaaccagg aacgatgaat tccatatatg aaaaaccacc catgtcaccg atccgcccac
    26521 cgatcatttt tccgaaaata acaaaataca aggatgtcgt gatcactggc ggaaccagtg
    26581 tttggaccca tatacgcaaa tagcggttcg tttccttgat agctaaactt tttaatgcag
    26641 taaaataaag attaaacatt tttctcctcc gtatgattat tttcttctgt gattttcaag
    26701 aacagttctt ctaaacgatt cgacttattc ctcatagaaa gaactttgat tccttgtctt
    26761 gtaagctgat cgaagattcc gttcacccct tgatttcgtt caacttcgac agcgattgtc
    26821 tgctcatctt caaatgtaca agcatatcct tcaatcacag gtttggtatc atatggcgct
    26881 aaatcaaaga taaatgtttc aaattgcagt tttgacagaa gctctttcat acttgtattc
    26941 tcgatcagtt cacccgattg gatgattccg atgttgcgac aaagcatttc agcttcttct
    27001 agataatgcg tcgtcaaaat gatcgttgta ccattttcgt tcaattctcg tagaaactcc
    27061 cacatctcgc gtctcaactc gatgtcaact cctgctgttg gttcatccaa gatcagcaaa
    27121 cgtggttcat gcatcaatgc cctagcaatc atcagtcttc gcttcattcc cccggaaagc
    27181 atacgtgcac ggacatttct cttttcccaa agattggact gcttcaaata tttttcgctg
    27241 cgtttcatcg cttctttgcg agagacaccg tagtagcctg cttgattcac gacgatttgc
    27301 tggaccgttt caaaagggtt aaaattgaac tcttgtggaa ccaatccaat ctgttgcttt
    27361 gctcgaacta gatccttgtc cagatcataa ccgaagacat tcacttttcc agatgtttta
    27421 ttgactaaag aagtaataat cccgatcgtt gtagacttcc cagctccatt tggccctaat
    27481 agcgcataga aatctccttc tttcaccgaa agatcgattc cccgcaatgc ttcgacccca
    27541 cttccataga tctttttcaa attatttatt tcaagcgcat ttgccattta tttcctatct
    27601 ccttatagac atgattctta attgtatcat ggaatacagc agatgaaaaa acaacttggc
    27661 ttccacacaa aaacacacct gctaacaaag aggagatgtg ttttctagtt catgatcatc
    27721 ttcgatagaa taactatcta aacaactctg gaacttttaa aatcataaaa gtaccgacag
    27781 caactactac gatgacatat agaagatcct tataactgag gttcttgtct tttttattca
    27841 tgttaagctt tcctccgtcc ttttatcgaa agcttttttc ttttatttta accgaaataa
    27901 ataaaatgga aatagttatt ttcaatttct gttttcgctg tttgttttac ggagaacttt
    27961 gccatggaac gtgcgtctcg tcgctgatgc taagtttttt cgataaaagc tgctagaagg
    28021 aagacagcgt ggtttatttt gtatcgtctt ttgctaaatc ttccaagatc atctggacag
    28081 cagactcgtt cccattgaat tctgccactt ttttggcatc aatgtacttc ttttgataat
    28141 cgtctttttg gacccacgca tcatgcttcg tttgataaag ttaatcaaac ggataccact
    28201 gacgctgttc atcgaacaac aaactttctt tttgggcctg ttcaactatg gatttaggat
    28261 aattcaaaac tttcagcaag gcaatcgcat ttcgggtcct tgaaggtcct tcttttaatt
    28321 tgaaatcaaa actgattcct tttccttctg ttacttgttc ttcaaagtgg acattctcac
    28381 aataattctt taaaatctct gtcaattcga tatcatgtgt ggcgacaaat gctaaagatg
    28441 gatactccgc aagccaccga acgactgaag cggaagaagc aatccgttcg atcgtatttg
    28501 ttccttttaa aatctcatct acgaagcagt agcagcgttc tttggaagcc acttggtcca
    28561 gcaaacgttt gatcgatttg atttctgaaa caaaataact gtcgccttca aataaatcat
    28621 cttcgattgc catggaagtc aacacatgtc caggttgcag ggtaaactgt tctgcaatcg
    28681 ctgtttggat cgtctgtgct agaatacagc tgatggctat acttttgaca tacgtagatt
    28741 ttcctgatgc attggaaccc gtgactaatg tattcttctg ccagttgact ggattaacta
    28801 ccgcttcttt taacaatgga tgatagatat ctttcgctgt cacaccgccc tcagtaaact
    28861 ctggtcggca agtgatcggc atataggtgc gataattcaa aacggctgct gcaacttcca
    28921 attctcccag caattcccac agcttgatgg cttcagttga atgcttttct aatttagtga
    28981 gaacgaaatg ataggagata aatggcagca tgaacatgat gttgacatat tcaaaaatca
    29041 attctgcttc actcccgctc ttcattcgaa atgaaaaacc taatttaggg atgtctctta
    29101 atggtttagt ttgctgtttc agctcttttt gaagtggtgt cgtcattttt gctaactgat
    29161 tggcggctga aatcgttgaa accaaataac tcatgctatt cagctctgtt tctagtgttt
    29221 gtttcttcac tagataatag accgtattga atactaagcc accgattgct agatagattc
    29281 ctagtacttg ccctaaaaga agcaaaccta cacccaccag cggaagcaag ccaagaaaaa
    29341 taaataaacc tacgcgtcca atctttttac tttttccatc cgctagatat tgttttgcaa
    29401 aattatgatc tttttttcct aaacgagcga attgatattg gattctttct ctcagttgag
    29461 gattttcctg ataaaaagca attagttttt ctaactgata atcttctcca aaatcaaagc
    29521 tacgtaaacg ctgatacaac gcttctgaac ctacactaga ataggtactg ttgatccctt
    29581 caaatacttc gaacatatcc aagtcatacc aagtaagatc gtcgatttca ctatcccatg
    29641 aacggaattt tttctccgtg agccacgcat ccttcaaact ttcttcttta tcaaatctcg
    29701 gttgataagg aatttttccc caattactac gaactgtttc ctttactttc aaacgtgaaa
    29761 aaatgtctaa aacaactaat aaaataacaa ctgcaataat aattaaaacg ataaattctc
    29821 tttggcccat atccctctcc gttccttgat ttgttagttt tagtatagca ctgttgcgct
    29881 atttgaaaag ggggtacaaa aataactgtc ttcgttacct aattcgtatc aatcacacca
    29941 aaataaaaac accttccaaa aaagaagatg tctttaaaac gagatacaat tttttgtcat
    30001 tcacttcagg taaattagag ccaattaaac cctccgcaac ttgacggaga tggagaagat
    30061 gcccccgtct aatctagcgg tcatctctcc tcccattcct tccaccaatt tttttgacag
    30121 gtaaagcccg attccgctag attccgtatt tgtgcggctg gtattttcgg tataaaaacg
    30181 ctggaagact ttttcaacag aggtttgcgc tcctggtttg ataggattgg ccactgttaa
    30241 tcgaatgaat gaatcctctt ttgaaaatgt cacctttgct tgtccatctg cataacgcaa
    30301 taaattctgt atgatatttt gcagcactcg cagcaacatg agcggatctg ctaatacagt
    30361 tgtatttatc gagtgttcag cgaacgctac ctcgatattt ttctcagaaa attgttcata
    30421 aaaagagaaa aatacttctt ccacctcttt agaaaaagaa agcgtatgga gatccatttc
    30481 tttttgcttc gtctctattc gagcaagatc ataaaactga tccgtcatac tgagtaatct
    30541 tgcaacagat tgtttgatga tcgttaaata cttctcccgt ttctccgtat cctctacctg
    30601 ttccagtaat tgtacataac cgttaatagc agtcaaagga gttctgagat catgagaaag
    30661 gccgacgatc gatagtctga tgttttcttc catttcttga aatgcttgtc ctttttgttc
    30721 attttcatcc acccatgtat tcagtgcatc tactaggtcc attagattct tttctcgaaa
    30781 ttcgactgaa agacgaccac catattcttg tcgttcagaa agagtggcga ttttcttagt
    30841 taatctcttg atttcccttt gcaggaagaa aataaaactt cccataaaga taacaacgag
    30901 aagcaacagc cacttaatca aatctaaacc ccactcccca caccgtatga atatacacag
    30961 catgtgcctt tgctagtttc cctcgaagat tggaaatatg catattcact gttttctcac
    31021 tatcaaaata tggttcttgc caaactgttt cataaagatt tgctcgcgaa aatacttttt
    31081 tcggatgttc taaaaaaagc ttcagcagat cgaattctct tcctgtcaaa tggacagcca
    31141 caccattcac atttacatcc ctcgactctt tgtccagtaa gatttccttg taatagatgc
    31201 gttgcgacag atcttttact tggacagaag tctgatgacg aagttggatg ccgattcgta
    31261 acaacagttc ttcgatatca aatggtttcg tcacatagtc atccgctcct gctgccaaca
    31321 aggaaacttt atctctttga tcgctttttg ctgaaagaac gatgatcgga acattcgatg
    31381 tctgtcggat ttctgctaac aatgcttcac ctgaaagccc tggaagcatg agatctagaa
    31441 ggatcaaatc gacaggatat gtgcttaaca ataattttcc ttccgtacct gaataagcat
    31501 caagaagttt gtatctctgt tcaagaacct cctccagtaa agaatgaaca gcttcatcgt
    31561 cttcgataat caaaatagtt tccagcagga acacctactt aatgtcagat ttttggaaaa
    31621 taaacattcc tagagctgat gataccacga ttgttactag actgaccaga atcattttcg
    31681 gtgcttgcga ataagttgct tgttgcgcaa agtccgtata catgagccac gtttccgtaa
    31741 accactccgt tagaaattcc aagcctttga tttttgcgaa aacaccggga acgaaggccg
    31801 ttcccatgat ataaagaaaa gaaagaagca aactgacact ggtacttcta gtgatgaatg
    31861 tcaaagccac tggaacagat aatgtcgcta atatcagcag aagcaataca ggaaatactt
    31921 ttagaacata atttccatag tttttgattc cctcaacttc accaaatccg aaagcaagtg
    31981 tgtaagcaat catggctagc cccgtaatca aaaccacgcc aagtgttgtg atcaaaagcg
    32041 taacgagaag tttcgacaca taataagtca ttcgattccg tcctaaagat aacgtattgc
    32101 gaatcgtacc gttttgaaat tcttccccaa tataaaagca cgcaaatgct gcgaaagcca
    32161 gaagaatcca tgcagccatt ttttccacca ttaaaatccc tgttgcaccg ttgatgactg
    32221 tatccgttgc ttggtttaat tcattgccgt attttgtatg catataccat tcgttccaag
    32281 aataaaaaag cggaagtacg accatcagtc ctagtgagac ccacatttta cggctcttcc
    32341 atacttttat tttttcagca gttaatagat taaacatgtg gattgcctcc agttaattgt
    32401 aagaaataat cttccagttt ttgcccaact aggtggatac catccacagg aacttttgcc
    32461 tctaccaatg cttgattgat ggctgctact tggtcaattc cttcaaaaag ctggataaca
    32521 cggctagatt ggacaaaata atccctataa ccaagagagt cgagaaccgt tactgcttgt
    32581 tccgtcgccg aagtgtcaat ttttataaat tgacgagatt cttgtgccaa ttcttctttc
    32641 gataattctt tgatcaagtg tccttcatgc aaaataccgt agtgagtggc gatctgtgac
    32701 aattcatcta gcaagtggct agaaagcaag acggtgatgc cccgttcttt taccaaacgt
    32761 tggatgattt ctcgcatttc tgccatccct gctggatcca tcccattcgt cggttcatcc
    32821 aaaatcaaaa attctggatt cgtgatcagt gcatttgcaa tagctaaacg ctggcgcata
    32881 cctaaagaga aattctttgc tttctttttc cctgtatttt ccaatcgcat cattttcagc
    32941 aggtcttcga tttctctatc cgacacaccg ccgttcgctg cttggatacg taggttatct
    33001 cttgcagtta attctggata aagagcaggg gtttcaatcg attgacccat acgtcgtctt
    33061 gctgcctgca aatccgtcgt tccaaataat tcgatcgaac cttcatcaat cgagatcaaa
    33121 cccataatag ttctcataaa ggtagactta cccgctccat tctccccaat caaaccatag
    33181 atcattccac gtttgatttc gatcgatact ttatctaatg ctttggcagc accgtatttt
    33241 ttggttatac cagttgcttt caagaccgtt tcatttccaa aatccatact tatccttctt
    33301 tcttattgat aagtgaagta tagttgacgg gtataaagaa agcagccaga aatgtataaa
    33361 gaaagtgtaa attttccaat tgaatttcaa gaaaaatcag actgtctcgc agacgtggtt
    33421 gagttgtctg ccaatcaaag agcgcaccaa acagtgctaa tccaagtgga ctggccacca
    33481 tggtaatcgt tgttatcgtt gacatcagac gtccttgtat atgcgttgga acttctcgct
    33541 gaagccagac catataaaaa gcaaaagaaa acattaatcc ttaaaaacgg acttatgaaa
    33601 aataatacat gccgtttggg atttacaatt agctaccaaa taagaggtta tgacaaaaga
    33661 cttttcacaa tcccttcttc cgaataaacg gtgttctcct gccaactcct cggtcacaag
    33721 tcacaatatt tatcaaacat gagaagcaat ttttgtaaat tccttcttat ttcttgaagc
    33781 tgaccacttc tgtcacaacc tcagaagcgg ataaataata ttgtttgatg atactttatc
    33841 tttttcccgt ttgtttatag atcgaatgat attatagacc aagaatccta cctattaaca
    33901 tagctaaaaa cacaaaaaag gcactttcca aattgtggaa agtgccagaa aagttaggat
    33961 taaggtaact gcgctcagca ttgcttcgcc cagtacgatt ctcgtaactc gtgaactcga
    34021 acgataatcg caattaacgt tttgagaact gtgaagcttt acgggctttc ttaagacctg
    34081 gttaaacaaa cttttgtttt ataatgtttt acagagaaag aaatcgtgta aaatcagcat
    34141 ttaatgattc atataattct acttagttaa ataaagttat atcctgtcat tacctcaaat
    34201 cattaccaca acttggcgag ttggctgatt gaagaatatt ctgtgccaaa taaaaaaaat
    34261 gatgccaaaa ataagtacac tactcaatac ttattttcaa catcattaat cctaaaatag
    34321 cttcgctttt acccgttact atctaccctt tcggaagggg tatttcatct gactaaagaa
    34381 tagcatccaa gataccaata gtcaagtaat taatttacca tactccatta caattttttc
    34441 aaaaaagtgg aaaacttcta caagttcatg attcttttcg tacattttac cattaacttt
    34501 tatgcgatca agtaaatcag atagagcctc aaagtttgtt gttttcaact tttgtgtttg
    34561 aacatatttt tcgtgaagat atatagtagc cacaatatca ttcattttca tattggtgag
    34621 tgctctggcg attagttcag aatcaagacc cgcattggtt gcaaactgtg ttaattgaat
    34681 aacaggcctt cttttcttca agttgctgtc agctctacca aattgataag gttcaacaat
    34741 attataaata agaggtctac tatgtgcaga ggcatttctg acattcgtaa catattttaa
    34801 taatttttga gctgttttta atcctagata tccaaaatgt tcttcttcaa aatagaaggt
    34861 gataaatctc tctaaatttc ctagggtcat aacttctaat aaagcccaaa ttgaaatctt
    34921 atcatgatga tgattataaa aatcaaaatc atatccgaac ttccctttca ctttatctag
    34981 aatcttttca gaagcttgtg tatattcaga caagatttct tcgtttgttt tagtattacc
    35041 tttttttctt tgactatcaa taaatttatt ttgcatatac atatcgtaat cttcaacaat
    35101 tttatatcca tcttcggtta atgaattagt gattgaactt attatcaaag ttttcaaaga
    35161 atgttcaagt tcaaaaatca ttctactcaa aatcattctt aaatacatat caatctttgc
    35221 taaatcagct aattttacaa atgataaatc tatatacttt ccatttatat ctttttcaaa
    35281 attcttacgg tatgcggtta ccttaaaata atacgttcga tataataaaa tatcctgaac
    35341 aatactttca tccgattcag aaatttctat tcctttaaat ctagcatatt taatttgatc
    35401 cgtaattgaa aaaatttcct tgtttttagc ttttttacaa agatctttaa tttcttctga
    35461 taattcttca gagacttgat taactctctc ttcttcttct aactgcaact ttaatttagc
    35521 caatttgtcg cttttaataa aaacacacct cctttatctc tttattttta tactatcttc
    35581 ccaacatctc cataaacttc cgcaattctt cttgcgcttc atctgttgtc ccgtgcaatt
    35641 cacctagcat ttcaaataat ttatctgtcg atttttctat ctcttgcttc acatctgcta
    35701 attcttgtgc aaggtgtggt aatggagtca cttcttcttc ctcaaacgtg tctacatatc
    35761 ttggaatgtt taggttataa tcattctctt taatttcgtc taaagttgct acatgtgcat
    35821 atttttcaac atcttcacgt ttttcatagg tttcaataat tttgtcaatg ttttctggtg
    35881 ataatttatt ctgatttttc cctttgacaa attcactaga agcatcaata aatagaatat
    35941 cttttgttct cctagattct cttcctttga ataccaacac agcagttgga atacttgtcc
    36001 cataaaatag atttgccggc aatccgataa cagtgtctaa caagttatta tcaatgatat
    36061 ttttccggat tctcccttca gaagctcctc ggaatagtac accatgaggc aatacaatcg
    36121 ccatcgttcc agttttatct aagtgataca ggccatgtag cacaaacgca tagtctgctt
    36181 tagaagcggg tgctacgcca taacctttaa accgtgtgtc tttttctcga tccacattct
    36241 ttatatccca cttagcagaa tatggcggat tagccactac agcatcaaat tttaatggaa
    36301 tttgcatacc atctttttct gcgaatggcc agtctgcatc aagggtatca ccacgtttca
    36361 aattcatatt tcgataatta ataccatgca tcatcagatt catacgagct aagttatagg
    36421 ttgtcgtatt caactcttgc ccatagaaat caacactgcc ttgcttattg ccatcgggta
    36481 gttcattttt cactgtcagc agcaacgagc ctgatcccat tgctggatca taaactcgaa
    36541 attgagtatc atccgctttc gcatctttgg ttacaatctt tgctagtact tggcttactt
    36601 catgtggggt ataaaattct ccaccttttt tccctgcatt ggcagcaaat tgaccaatta
    36661 agtattcata cacatcaccc aggatatcgt gaccagaatc atctttaaag gtaaaatcgt
    36721 tcaccatcaa aacaacatca ttcaaggctt ttgctcgttc attcgtattt gatcctaacc
    36781 gagtatctcc aagattaatg tccgaaaaaa cattggcaaa atcatcttcg gcaactggat
    36841 tccgtttcgc attcaaattg aacgaatcaa gcatatcctg aaagtcactc gctttgattt
    36901 ggtggttttc aatctttgat actaactgtt cccaagtata ttccggagca atcgcataac
    36961 cgattcctcg actgatttct tccaagtaat cttctttttc ttcagagtca gtgacttcgt
    37021 agtactcgtc taacccattt ttttctaaat actcgtcttg attttctgat aagtagcggt
    37081 agaacataaa tggtaaaata taatttttat actcacttgc atccattgtt ccacgtaatt
    37141 tattggccat tgcccataat tttgctgtaa tctcacttgc attactcatt aattttctct
    37201 ccttttagac aaacattttt tgtagcaatg tttttttcat ttcttttagt gaatccaact
    37261 cacgctgatg aagggtgatg gtggtgtcga gacttttaaa gaagtccgca attttttctt
    37321 gctcgttatt attttttgga atcatgagtt cagtttcaaa aaaatcagat gcagcaatat
    37381 ttaaaagccc atgattccta gctccctcag cagcatgctt agaaacctct ttataccaac
    37441 gatctgtatc ataatatgac gctaaaaaat ctgaatttat gtcgaccggt ctaaaacaaa
    37501 tatacaatgt tgataataca cccatgtcat acttatctag tcgcttaaca gcaccccaag
    37561 gatagccatt ggagtagctt ttattatagg caaactcacc tttcttcagc agataatatc
    37621 cgctaacatc cttactggca atttgcttat taaaaaaagt attctgatca actaatccaa
    37681 attgtgctga tatagtcagt ggaagtgttg attcaagctt tttgttcttt ctggtcaccc
    37741 tagtggcaac ttcccccaac ttacgctgtt cccaagcgtc agtaaatcca gcaaaacgaa
    37801 tttctggttt atcttcacct gttttaggaa acattttttt taaataagtt tgttttgttt
    37861 gctctaacag atcaagctca cgctgatgaa gggtgatggt cgtgtcaagg ctctcaaaaa
    37921 aggtagaaat ttgcttttgt tcttcaatac taggaaccat tactttaact gattttagcg
    37981 ttggaaattt caaattccat gtatcagatg ttaagccttg tgagtttctc ttgaacgttt
    38041 gaatcatgtc atatcgcttg aaatcatacg caaagaactt cgagtcaata tctttttttg
    38101 gaatgataac tgtgtatgca gggcttagaa tgccattata aggggaatat ccgcttgcac
    38161 cttgccacat tctcattgag ttgtatgcaa tatcaccaac ttcaactttc ttgtaatttg
    38221 acttgtcatc actggaatta tcttttctat caagttcgct tgcctttaca actcctgaat
    38281 taatagtgac cgagataagc tctccttcgc cactacgttc tgaccgttca gagaacacct
    38341 ccccaacctt acgctcttcc caatctccct cgtatccgtc aaatcgaatt tcaggttctt
    38401 ttgttatttc attgctcatt ttaactctcc ttcgatcttc gttatctcct tatcaaaatc
    38461 agaaacgata tgctgatgtt tattgaactc cttgtactca tcaaccgctt ttctcttagc
    38521 tgctttactg ctaatttttc cgtttccatc aagaatttga tagcgattaa atgttagaaa
    38581 ttcatctatg cttttggcaa aatcttccat acctaaaagt gtttcatctt ccaataatcg
    38641 ctcaacataa tcaaaataag aagatacgtt ccgttcaaga ctgcgaattt gtttttctga
    38701 taaataattt ttagcaactg atacatctga ctgtaggatt cttccatctg gagagttttt
    38761 ccaagtcgtc agtcccatgt tctcttttgt tttatctgca ccattaaaaa caatctccgc
    38821 agctgttttt ccagtaatag catagtgaaa tttattttgt acagtggcat aaaactgctt
    38881 cgtaatttca gagtttttgt cataatcata agagatttct gcaaatacat cagtaatttg
    38941 ttgccaaatt cttcgttcac tggcacgaat tgagcgaacc gtttctaata actctcggaa
    39001 gtaatccttt ccaaaagcat tctcaccttg tttcattcgc tctacgtcaa ttttgaagcc
    39061 cttttgaata tagtctttca gaatatctgt tgcccagatt cgaaattttg ttgctttttg
    39121 agaattaact cggtaaccaa tagaaataat cgcatcgaga ttataatatt tgaccttatt
    39181 tgtttgtgtt tttccatcta ttgcgccatg ttgagtggta ttttccaaaa tggaaacaac
    39241 cacttcttca tctaattcac cagactcaaa tatatttttt aaatgcttgc taattgctgg
    39301 taccccaaca tcaaaaagtt gtgaaatcgt cttttgcgtc gcccaaattg tctcttctcg
    39361 aataagcact tcgactttat cactatcttc ataaattaaa aactgaattt cattcaatag
    39421 aacttactcc cctttcttag tctcgtccgc catctgatag aaagctttcc gaaattcaat
    39481 tcgatactta acccatgaaa gattcgccac ttccgctgct gcgatttctt tataatctgt
    39541 tcgtgcatcg ttcatcattg ctgttagttc accttgtttg tccatatctt cttgaccaac
    39601 tcgatgccgt gaaattaatt tggctaaatc ttttggcttc acactattat ccaatcccca
    39661 tgtgcgaaca aattctgtat atagtttgat attgctatct ttttgagatt gttccatcgc
    39721 ttgattcatt tcttcaacat ctctaggagc cggatactta tcaaagatga attccttcgt
    39781 aaagatcttg gaaacaaaat tgcgaacttt cgtaatctcc ttatcgctat ccgattttgc
    39841 aatttcaaca tcgatctcat tttttgtcag ctcagcttga tccattttat cttcatgaac
    39901 ctcatctgcc attcgtgcga tcaattcaat cagataatca taattgatcg tcacatcgtg
    39961 aatatgcgtc atctctaaat tgacttgcga tatatcgata ttttcgattt gggctcggcg
    40021 ttcacgcaac tcgttagcaa gtaccgttgt cagcatgacc tcttgatcct ctgtaattcc
    40081 taagcggtca tagaacagtt ccggttcatc ataaacagaa acaggatttt tttcatcgtc
    40141 ctccgtgaat tgcttcagtt gatttagtaa tcgattgtac tcctgtaatc cttcaaatac
    40201 ttcctcttgc gctttttcac ttggaggtaa ttgaataaaa ttatctgtta gttcagctaa
    40261 tttctgaatc acttctttgg tttctgattc gattttacta aatgatttcg ataaaattcc
    40321 cgactcttca ttgtcttttt ttaattcatc tagcgatagt tgctctgctg ctgaatctcg
    40381 atttgaataa atagcaaaag acttattcat ttcgtattca ttttggatgg gccaacgata
    40441 attaacaata tttccttgtg gctttgcatc cctatcatgg attctattcg tacgtgaata
    40501 tgcttgaatt agattgccac cttttaacgt acgatcaatg tacaatgtat taagctccgg
    40561 tgcatcaaaa cctgttaata gttgatccac gacaatgact agatccaaat aatttccatc
    40621 gtcagctgtt ttgttcaaac gtctagctaa atcttctgta tatgatttaa ctgtcgtcat
    40681 atcaaaagca gtaccaaaca atctattata agattgaatt gctcggtgaa gattttcatt
    40741 tgtttttagc tgatgactac tatttgatgt atccatcgaa aaactaatgg caacttttat
    40801 ctgatcctca attgaccgtt tattattttc ttccataaat ttatcaaaat attccattgc
    40861 tcgaggagta ctagcacgat ttccccctac atgtactgta aataacgcat tgtatttccg
    40921 attattagag cgttctttcc agttatcaaa aatatcttca acaacgagtt ctacatgctc
    40981 gggactatga tcatacacac tgccacgaag attgtcgtca atatcttctt ctgtaggatc
    41041 tgctggtgct tcaatcgtct ccttaaactc cactttgaat cccaaaacgt ttttatcagc
    41101 gatagcttct ttaatcgtat aagcatgtaa taagtcacca aaaatttctc gcgtttctgg
    41161 aaacttaggt gtacctgtat aaccaaccca agcagagtta ggcaaggctt ttcgaataga
    41221 ttctagcatc ccttcatttt tagtcccatc acctgttgaa cgatgtgctt catcaacaat
    41281 aaataataca ttctcagtta atggttgaaa gctgtctctt gttacatatc gagacatttt
    41341 ttgaatactt gttactatga tgtttttatc actttttttg gtaagtttac ggtgcaagtc
    41401 agaaatattg gcagtatcac ttacaacacc agttttccct tcaaatccag cgattggatc
    41461 atatgctcta taggcatctg ctgtctggtt tgtcaatgca attcggtcta ccaagaaaat
    41521 aaccttgtct acatttgata agcgactcgc taaccatgcc gttttaaaac ttgtaatcgt
    41581 ttttcctgaa cctgtcgtat gccaaatata gcctagcttg ccctcgtcat gcttaaaatc
    41641 aaatttccta actttatcaa gtacccgttt tgttgcatag acttgatacg gacgcatgac
    41701 tttgatactt tctttgttct ttgtaccatc caacaccata tatcgagtag ataaatcatg
    41761 ggccatggga atagacaata ctttatctgc aaacagtttc catgaacgta ctggatgagc
    41821 tgtttcttca tcttgccaat tgaaagcaaa tgcacgattg aaattttgta atgtagtatt
    41881 tgccatgtaa cgaatatcaa acggggtcat cgcaatgagt atctgtaagg tagaaaaaat
    41941 cccactaaat tgtttctcag caatatattg ttccatttga tttaaagctt ctgtcgcatt
    42001 atgtagcgcc tttttcaact caatttgaat aatcggtaac ccattaatca aaagcgtaat
    42061 atcaaaccga cgattgggct taccatcaac aacttttgga cgttgaattt gattaacgac
    42121 ttgatagact gtatttccgc cgccaacttg ggcttgatca aaaacggtca aaaaaacatg
    42181 ctttccgtta tcaagatcaa cttcaatttc tgatacacca tttacaccat ataaaaattg
    42241 tccagcttga taaggcgtat taatattggt aataattttt ttcacttgat tgaactctgt
    42301 tgcagataac ggttcatcta gccgagcttg attattttgt tctagaattt ttttgaagtt
    42361 gttccataat tgttctgttg ttttaatttc agctttatat tcccattgtt ttacgccacc
    42421 gattcttgtt agataatcca caacttcttg ctcgaacctt aattcagatt gactttttat
    42481 accgaattgc tttgtcataa tctattcctc caaacttttt tctaacatag aatttgtaaa
    42541 ttgctctaac aagcgagtat atatacttaa cttactttgt aatttcaatg attcagtgta
    42601 aatcccccct atttttcttt gttcttctat aagaggtagc ggaataacaa gttgttccag
    42661 agactgtttt gttaacctta aaactggacc tgttccttga agacctcgat ctttttgacg
    42721 ttgaatatct ttatgattgt taaataagta aagaaaatag cgcttgtcta gcaaatcact
    42781 tttaaactct acttttgtaa aatttagaga cagaacttta ccaacattct gtccacttac
    42841 cattgttgcc cgttgaagtg aattactaat aacaacatcg cgtttatcta aagatacttc
    42901 ttgatcaaat aaatagttta ctctttcctc ttgagtcgct tcattataat acttatgatc
    42961 ttcttcaaat gaagcttgat cgtaataatc aatttcttga ttgccaaact gtttttcagc
    43021 tcttgattga ttaattcctt gaacaaaggt tacaaactca gaaagctttc tcatttccat
    43081 atatacttcc tcctaaaata caattcaggt ctcatttaaa cgatttatcg aaataatcat
    43141 atatttcttt ttcgtttctg cgtttttata ataaacctta tacagtaatt cgtcaatgga
    43201 aataatttta tattacaaaa aatccgcaaa aaatgcggat tcctttaaat atttaatctt
    43261 tattctagtg tagtacaagc ctatacccta acgttacata tctcattcat tattatacca
    43321 gtatttcttc atgacacata agggtgtaac ataataattt taaacgaaat gactacaagt
    43381 agtcattgaa gtaagtcttc ataagatacc tgtaggatat ccctaattgc tctcaattga
    43441 tctaacttaa tgtgttgccg gccaccttca attttaacca atgtttccct agttatagca
    43501 attttatgaa gctgtaggtc tctaatcagc tcggtttgac caattccttt ttctaatcgg
    43561 attcgtctaa tattgctacc gattacattt tctttatcaa taattttttc ctctttcaag
    43621 aatagcacac cttttggact aaaattagtc ctttttctta ttaatcttaa agattcggta
    43681 tgctacaatg ggactagtat tagtccacat tcaattttaa ggaggaattt ttttgaagaa
    43741 atttgcaatc attctaacct gcgctttact catcggaact ataagcgggt gtaccacttc
    43801 tgaaacaagt tctacaagta cggaaactag tacaacaacc tcagaaaaga attacccaat
    43861 acattttttt ccggttccag atggatttga agcttattat catgataaaa aactagatgt
    43921 ccctttatca gaaactgaat ctactgaaaa gattttgcca attgaaattg aaagaaatca
    43981 agacgatata aaactaaaag ctgatcttcc cttactgaac agcacacaaa ttgatagaca
    44041 tgaaaatatt aaagttaata ttgaaaaagg agcg
//
LOCUS       DACDAF010000013        44001 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.013, whole genome shotgun sequence.
ACCESSION   DACDAF010000013 DACDAF010000000
VERSION     DACDAF010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 44001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44001
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.013"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(119..709)
                     /locus_tag="IVZ69_000668"
     CDS             complement(119..709)
                     /locus_tag="IVZ69_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HAP8182780.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
     gene            1232..1393
                     /locus_tag="IVZ69_000669"
     CDS             1232..1393
                     /locus_tag="IVZ69_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182781.1"
                     /translation="MEPKDKYLDYARVNKDKFIETIIKGKIPDDEKDAVFMAGSPGAG
                     KTEVALGLA"
     gene            1412..1906
                     /locus_tag="IVZ69_000670"
     CDS             1412..1906
                     /locus_tag="IVZ69_000670"
                     /inference="COORDINATES: protein motif:HMM:NF018154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin"
                     /protein_id="HAP8182782.1"
                     /translation="MIDADYFRAQFPEYNGKNSSVFQKASSWLVEQSLKYVLEHGYSF
                     ILEDTFAILSAEKNIIRALKNNFRVTIFYVYQDPKVAWDFTRKRELAEGRHVPKEMFI
                     NAFFKSRENIEKVKNRHPEVVLHIMIKDYQNDISEVHYAADNIQLVLPIQYTSKELEE
                     ELHD"
     gene            2544..3567
                     /locus_tag="IVZ69_000671"
                     /pseudo
     CDS             2544..3567
                     /locus_tag="IVZ69_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            3910..4166
                     /locus_tag="IVZ69_000672"
                     /pseudo
     CDS             3910..4166
                     /locus_tag="IVZ69_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            4553..4780
                     /locus_tag="IVZ69_000673"
     CDS             4553..4780
                     /locus_tag="IVZ69_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HAP8182783.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            4796..5962
                     /locus_tag="IVZ69_000674"
     CDS             4796..5962
                     /locus_tag="IVZ69_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HAP8182784.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            6197..7240
                     /gene="hrcA"
                     /locus_tag="IVZ69_000675"
     CDS             6197..7240
                     /gene="hrcA"
                     /locus_tag="IVZ69_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HAP8182785.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            7334..7897
                     /gene="grpE"
                     /locus_tag="IVZ69_000676"
     CDS             7334..7897
                     /gene="grpE"
                     /locus_tag="IVZ69_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HAP8182786.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            7948..9777
                     /gene="dnaK"
                     /locus_tag="IVZ69_000677"
     CDS             7948..9777
                     /gene="dnaK"
                     /locus_tag="IVZ69_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HAP8182787.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            9928..11094
                     /gene="dnaJ"
                     /locus_tag="IVZ69_000678"
     CDS             9928..11094
                     /gene="dnaJ"
                     /locus_tag="IVZ69_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HAP8182788.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            11256..11417
                     /locus_tag="IVZ69_000679"
     CDS             11256..11417
                     /locus_tag="IVZ69_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP8182789.1"
                     /translation="MIIIVSEGGIDYVLDIVNEPMVLSYAMEQVERLLVCAGEQAMRL
                     VQLSEKTRN"
     gene            complement(11462..12199)
                     /locus_tag="IVZ69_000680"
     CDS             complement(11462..12199)
                     /locus_tag="IVZ69_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP8182790.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(12201..13703)
                     /locus_tag="IVZ69_000681"
     CDS             complement(12201..13703)
                     /locus_tag="IVZ69_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP8182791.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            13962..15956
                     /gene="uvrB"
                     /locus_tag="IVZ69_000682"
     CDS             13962..15956
                     /gene="uvrB"
                     /locus_tag="IVZ69_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HAP8182792.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            15966..18782
                     /gene="uvrA"
                     /locus_tag="IVZ69_000683"
     CDS             15966..18782
                     /gene="uvrA"
                     /locus_tag="IVZ69_000683"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HAP8182793.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            19045..20310
                     /locus_tag="IVZ69_000684"
     CDS             19045..20310
                     /locus_tag="IVZ69_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HAP8182794.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            20314..21045
                     /locus_tag="IVZ69_000685"
     CDS             20314..21045
                     /locus_tag="IVZ69_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HAP8182795.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            21180..22064
                     /gene="rapZ"
                     /locus_tag="IVZ69_000686"
     CDS             21180..22064
                     /gene="rapZ"
                     /locus_tag="IVZ69_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HAP8182796.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            22061..23059
                     /locus_tag="IVZ69_000687"
     CDS             22061..23059
                     /locus_tag="IVZ69_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HAP8182797.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            23093..24028
                     /gene="whiA"
                     /locus_tag="IVZ69_000688"
     CDS             23093..24028
                     /gene="whiA"
                     /locus_tag="IVZ69_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HAP8182798.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            24596..25252
                     /locus_tag="IVZ69_000689"
     CDS             24596..25252
                     /locus_tag="IVZ69_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182799.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            25431..25996
                     /locus_tag="IVZ69_000690"
                     /pseudo
     CDS             25431..25996
                     /locus_tag="IVZ69_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26695..27216)
                     /locus_tag="IVZ69_000691"
     CDS             complement(26695..27216)
                     /locus_tag="IVZ69_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP8182800.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            27414..31094
                     /gene="nifJ"
                     /locus_tag="IVZ69_000692"
     CDS             27414..31094
                     /gene="nifJ"
                     /locus_tag="IVZ69_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HAP8182801.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            31283..32170
                     /locus_tag="IVZ69_000693"
     CDS             31283..32170
                     /locus_tag="IVZ69_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HAP8182802.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            32167..33336
                     /locus_tag="IVZ69_000694"
     CDS             32167..33336
                     /locus_tag="IVZ69_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182803.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            33360..34715
                     /locus_tag="IVZ69_000695"
     CDS             33360..34715
                     /locus_tag="IVZ69_000695"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HAP8182804.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(34787..36592)
                     /gene="glmS"
                     /locus_tag="IVZ69_000696"
     CDS             complement(34787..36592)
                     /gene="glmS"
                     /locus_tag="IVZ69_000696"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HAP8182805.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            37002..37292
                     /locus_tag="IVZ69_000697"
     CDS             37002..37292
                     /locus_tag="IVZ69_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182806.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            37305..38330
                     /gene="sppA"
                     /locus_tag="IVZ69_000698"
     CDS             37305..38330
                     /gene="sppA"
                     /locus_tag="IVZ69_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HAP8182807.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            38333..38992
                     /locus_tag="IVZ69_000699"
     CDS             38333..38992
                     /locus_tag="IVZ69_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HAP8182808.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            39149..40081
                     /locus_tag="IVZ69_000700"
     CDS             39149..40081
                     /locus_tag="IVZ69_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182809.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            40235..41524
                     /locus_tag="IVZ69_000701"
     CDS             40235..41524
                     /locus_tag="IVZ69_000701"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HAP8182810.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            41771..43021
                     /gene="clpX"
                     /locus_tag="IVZ69_000702"
     CDS             41771..43021
                     /gene="clpX"
                     /locus_tag="IVZ69_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HAP8182811.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            43104..43691
                     /locus_tag="IVZ69_000703"
     CDS             43104..43691
                     /locus_tag="IVZ69_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HAP8182812.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
BASE COUNT        14629 a         7475 c         9420 g        12477 t
ORIGIN      
        1 ctatgaatat aaatagagtg tatcttcttt gataaatgtc agaaaaagtg tgacaaataa
       61 ccatcagtaa aattacttgt catactattg ataaggagta tttaattgaa gagaatgatt
      121 aggagaaagg atctccgtac tttttatagt aatcatagaa tccaagtttg tatagacgaa
      181 tctttttttc tcttatttct tctgtttcaa aatggactgc ttgaagaatc aagtctgtga
      241 attctatagg agctgttcca ttcgcagtaa tcaaattacg atctttcaca gcttgttgtt
      301 ctataaaatc ttctttattc tgataatttt ccgattctaa ccaaggaaat tgcgcatttc
      361 cggtgtgttt gtaaccttgc aataatccgc tctgagctaa ataatcaact gccccacaaa
      421 tagcagctac tggtacgtct gtttttaaca atttatcgat tatttgatat aaatgatgat
      481 tttttatgtc ccatgaattg ccaccgatca taataaaaag gtcaactttt tcaggtattt
      541 gttcgattaa gtaatcgatt tttgttttta atcctccaat ggaagtgacc tctgattgga
      601 tagaagcagt tttgttttgc catccctctt tttggtttag tgtgctagta atataagcac
      661 cttcccaatc ggcatattcc tctaatagaa acgtaatcgc agttttcatt ttcaagctct
      721 cctttactat ctatgacaag gacaacagtt ttaacataca gacattcatt aaatttggat
      781 agcgacagcg aaaacaacaa ttcttaagtt ttagacagag tatacagaca gtcaacttaa
      841 ttaaatacga actaaataaa aatgacaggt aatcattttt gtttaccagc attataacat
      901 tttgcataca tggatgacaa aagaaccaat tcccacttgc ttgagtacaa tcttaaaaga
      961 aactggaagg caaaaagtaa ttatagaaac gaaaaataaa tcatatcggg cactcagaca
     1021 tgaaaacaac cctagaaata tataactagt ccaatgaaaa aaaagcgaat gccgtagaaa
     1081 acaaggattc tgcgtacatt catatctcat tttgcgagca tatctgctat tactgtgact
     1141 aaatgttaat atggttaaaa tgaccgttat attttttata taaatatcgt ataattagta
     1201 tgaatataga agaaggaaag aaggtgcaat cttggaacct aaagacaagt atttagatta
     1261 cgctagggtc aataaagata aatttattga aacaatcatc aagggaaaaa tccctgatga
     1321 tgaaaaagat gcggtattca tggctggaag cccaggagca ggtaaaacag aggttgcact
     1381 aggtttagct taaaattatg acaaccatgt tgtgattgat gcggactatt ttagagcaca
     1441 atttccagaa tacaatggaa agaactcaag tgtttttcag aaagcttctt cttggttagt
     1501 tgaacaatca ttaaaatatg tactggaaca tggctattct ttcatactag aggatacttt
     1561 tgctatcctt agtgcagaga aaaatattat tcgagccctt aaaaataact ttcgcgttac
     1621 gattttctat gtttaccaag atcccaaagt tgcctgggat ttcactcgaa aacgtgaact
     1681 agctgaagga cgtcatgtgc caaaagaaat gtttatcaat gcgtttttta agtccagaga
     1741 gaatattgaa aaagtcaaaa atagacatcc tgaagtagtc cttcacataa tgattaagga
     1801 ttatcaaaac gacatttctg aagtgcatta tgcagcagat aatattcaat tagtactacc
     1861 aatacaatat acttcaaaag agttggagga ggaattacat gactgagaaa gaacaagtac
     1921 aacaaatcgt gaagaagtat aataaaagta tcgctgattt atcagaaaac gcctcagcga
     1981 aagaatttaa aacagtaatg aattacgtag cagatgaagc aaatcgtaag cagcgaaaac
     2041 tagttgggtt ggataaataa attttttaaa ccatatcctt gtaaagttga gttttttatt
     2101 ttaatgaatt aagactatta aatagataat tattgtaact taaaaaacac agctaaaaat
     2161 tagttgtgtt ttttattagg tttacttttc tggtataaaa ggaactagct actttttcaa
     2221 aatttctaaa tcattcaata tgtagcgctt actaaattat tcgccataaa attttataat
     2281 tggatcactc attgttttac ctaagtcata tttaagtaat aaccggtgtt tttacataag
     2341 aagacttcgg gtatttttta gtttgattag ctctgatata cctataaaga atatgctaag
     2401 gtaagaatag taaaaattca catagatgag gtataataat gatattttta tatattacag
     2461 ataacttgac acaaaatgag tttttttcga tttttcaagt tatctaatgc aattatattg
     2521 atatcattag gagctgcatt gttatgaatc caacattgat tactaagaaa gaattactaa
     2581 aaaaattaga tatttctact ggtgtattag ctaatttaat tagaaatggc atgccaaaag
     2641 agggagaaat gtttaatctt gataagatta ttacatggcg agaaaattgg tctaaaaaca
     2701 tattaggtga gttagaagtt ggtagagtat atactaacaa agaaatttca gagaagttta
     2761 aatgttccaa acagggtgga atgagaagat ctcatcaaac taatactctt gtactgttta
     2821 gtgatcaaac aggaagtaat gtttataaag ataagtggtt aaatggtatt ttacaatata
     2881 ccggtatggg gctaaaaggg gatcaagtat tggataagaa tcaaaataaa gttttagcca
     2941 attcaaaaag taattttgta aagattcatt tatttgaaac atttaaacca aaagaacaca
     3001 catatctggg agaagtatat ttagcaggac aaatatatac tgttaatgaa aaagatagtt
     3061 cgggcaacag cagaaaagta tataaatttc cattagcttt aataaatcaa gagcaattga
     3121 ttgaagataa agatatataa ccaggaagaa aatcaaacta gacatattcg taatttatct
     3181 aatgctaaat tagaggaaga agcaagaaaa gttagtaatt ataataaaaa aatggctgca
     3241 aaatatgtta acgaagagga gttttgcttc tcaaaaacaa aaatatataa acgtaatccc
     3301 ttcgtatctg aatatgttaa acgacttgca aaaggtattt gtcaactttg ccaagaaaaa
     3361 gggccattta taaaagacgg tgtaccttat ttacattgtc atcatataga atatttgtcg
     3421 caaggtggaa aagatgtgat tgaaaactgt atcgcgttat gtcccaattg tcatgctaga
     3481 attcatgaac ttgagttacc tgacgataaa gaaaaattgc tgaagatcgt tgaaaaaaga
     3541 gaaaatagct tttctaaaat accgtaattt atttttatag gacaaataag ctaatgtgag
     3601 ctatgccttc tatataagac taagttctat tataagtaac gaagtaattc tcgttccttc
     3661 ctgtagtaat attttttaaa taacctatag gcttcttcaa aagtacatcc tccagtaaat
     3721 tctaagtact ggaggattct ttttctagtg ttgctttact catgaaaaag tagttggcta
     3781 cttcatcaaa atttctgaac ttttttaatg tataataaag agctcgatca tttactacaa
     3841 ggatgctagc tcctacattt tcacagtttt ttagcaagta aatttttcta aaatcacatc
     3901 aggaaatgca tgagattctt taagagaggc aattataggg ctatgattac ggttcgtgta
     3961 agtgacgcca aaaaagaatg gctttcttat atggctgaat tttatgggat tactttatct
     4021 gaacttctaa aaaactattc gatggaacaa ctagaagatg aatacaatcg tcaaacggct
     4081 gaaattgccc ataaacattg gataagaagt gggaaaacaa cagtattcat ggaagaatcc
     4141 ttaatgaatt tggtgggctg gaatgacctg ccgtttaaaa ttcacgcccg aaattcagaa
     4201 gcagctctga ttggcaaata cgtgtattgg tagagataga agataatcaa ttcgttgtta
     4261 tcgctattca agtagggcac cgaagaaatg tctatgatta agagactgtt tatttttaca
     4321 aaaaaataat aattggaatc tagttaaaac tcttgaagtg agagatttga ctagattttt
     4381 ttatgaataa aataaggaca aaattgttta ggaagaatca tgagtgtaaa aaaatcatcc
     4441 aagaagtcga ttcttggatt ttttagtgga tttgttcgcc aaatacgttt agtatgcgta
     4501 tatgagaggt tgtaagcaaa gcgttgtggt ctgagcactt aaggaggaat ctgtgaaaat
     4561 agcttttcat atttttgcag attttgactt aatgccgaag gtcagctttg cgattaccgt
     4621 ttatcgagag gctgtaaaag caccgtgtag ctccgatgac aataagcaag catttttaga
     4681 gctaggtttc cttgattcta aatatgcggc ttatttcaat gagttggtgc ttgaacgcga
     4741 ttttaagaag gtcgaaaaca ggcacgactt ttcgacgtaa ggagaaagaa tttcaatgat
     4801 agaaacaata aatcccgcag aaaacaaggt ttctgcgtac attcatatcc cattttgcga
     4861 gcatatctgc tattactgtg actttaataa agttttttta gaagggcagc cagtagatga
     4921 gtatgtggaa atgctgctga atgaaatgag attaatgctg gaaagtcatc ctacagcgaa
     4981 tttggaaaca ctttatgtag gaggcggaac accaacttct ttatctgcta aacaacttga
     5041 tcgactatta tcaggtgcta gagagatcct gccttttcaa aatggtaatg agtttactgt
     5101 agaagcgaat cctggtgatt tgacccgtga aaaacttcaa gtgatgaaaa actatggcgt
     5161 caatcgttta tccatgggag tgcagacatt tgacaatcgc ttattgaaaa aaattggacg
     5221 taaacatact gcagaagatg tgtatcaaac aatgcaattt ttagaagcag aaaattttac
     5281 caatgtaagc atcgatttga tttatgcatt accgggacaa acactagaag gatatcggga
     5341 tactttggaa aaagctttgg ctttggatct gcctcactat tctttgtact cattgatcct
     5401 cgaaaacaaa acaatgttca tgaactgggt acgacaagga agactcgaac tgcctgatca
     5461 ggaaacggaa accagaatgt ttgaagagac gattgaagca atggaaaagc atggacgtca
     5521 ccaatatgaa ataagtaact ttgggctctc cggacatgaa tctcaacata acctcatgta
     5581 ctggaacaat gaccactatt ttgggtttgg agctggtgct agcggttatc ttggagatat
     5641 tcgttaccgc aacaaaggac caatccaaca ctatttacgc ccattacgag caaatgaacg
     5701 cccggtattg gaagaagaaa aattgacacg aaaaaatcaa atagaagaag aaatgttctt
     5761 aggactaaga aaaaaaacag ggattactaa aaaacatttc tatgatcgct atcaaaaaac
     5821 aattgaatcg gtgtacggtg atgtgctaag ggaattagag caagaagggt tacttgttaa
     5881 tgaagaagac cgtgtttatt tgacaccaag agggactttt ttggggaaca atgtgtttga
     5941 gcgcttttta tttgaaaaat agtttgaaga atatttgttt tttatcgaaa cttgaaaaga
     6001 aaaagtttag aaagtttgac aatgaggtat tgaagtattg atataactgg atttacatca
     6061 attatttaga attagcactc ttgtgtttag agtgctaaaa aatggagtct ttctcttgac
     6121 aggagaaggg cttcttgcta tatttataag tgaattagca cttagaatat atgagtgcta
     6181 atgagaggtg aggaagatgt taacaaagcg acaaaacgac attttacgtc tgatcatcca
     6241 acactatacg agtagtggcg tgcccgttgg ttccaaaaca ttaatgtctg agggagtcaa
     6301 ggccagctca gcaacgattc gcaatgatat gaaagcatta gaagatgaag gattgctgtt
     6361 gaagactcac tcttcttctg ggcggattcc atctgcttta ggctatcgtt attacgtgga
     6421 tcatttgtta aaacctgctc gcgtagcaga agatgatttg ctgctgattc gtcagtctct
     6481 aggcagagaa tttcatgaaa tcaatgagat tattaagcaa tctgctgaga tattatctga
     6541 gctgacaagc tatacgactt tttcattggg acctgaaata aaagaccgcc gactgactgg
     6601 ctttcgtatc gtacccttga ataatcgaca gattattgct atcgtcgtaa cagatatggg
     6661 gaatgtagaa agccaagtgt tcactcttcc cgaatatatg ggaagtcagg aactagaaaa
     6721 aatggtacag attgtaaacg accgtctagt cggagatcct ctgatgacgg tgtaccataa
     6781 acttcgtacg gagattccga tgattcttca taaatatttc cagacgacag aagggatgtc
     6841 tcagttattt gacaccgttc ttggtcatgt ttttgaagaa aaggtttatg tcagtggaca
     6901 aatgaatctc ttggattatg agccccgtca agatcttgat cagttcaaat cgatgttttc
     6961 ttttatgaaa gactcagacg gacttacaca aatgatcact ccgatggata gcaatattca
     7021 tatcaagatt ggtgctgaat taggcaatga tttattgcag aatatgagta tgattcaagc
     7081 aagttacgag atagatggtc atggaagagg tacaatagcc ttgttagggc ctactagtat
     7141 gccttattct cggatgttcg gtctagtcga tgtttatcga agagaactag cagctaaact
     7201 tgctgattac taccgctcgc ttgacttgtc aaactcgtaa tgtgaataac gaagctattt
     7261 gcagctgatc gttctctctt tcttagtaag agcaatcaaa cagctgactg aataatgaaa
     7321 ggaagactgt atcgtgaaag aaaatcaaga agaactagat aaagaaatga cagatgctca
     7381 gccagaaccg gaaatcgatg tcgaagctgc agaagattcg ggtatttcag aagctgaagc
     7441 ggaagaattc gaaacagcga aattaaaagc tgagttagaa gaaatggaag ataaatactt
     7501 gcgggctcgt gctgaaatcg caaatatggc aaatcgagga aaaaatgagc gtgagcaatt
     7561 acaaaaatac cgttcacaag atttagccaa aaaattactt ccatcaattg acaacctgga
     7621 acgtgcatta gccacagaag tgtcagatga tcaaggggca ggtttgaaaa aaggcgtgga
     7681 aatggtcttg gaaagtttgc gtaacgcact ggaagaagaa ggaattgaaa aaatccctgc
     7741 taaaggagaa gcctttgatc ctaatcttca tcaagcagta caaactgttc cagcgactga
     7801 agatacacca gccgatacga ttgtagaagt actacaagaa ggctacaaat tacatgatcg
     7861 cgtgttaaga ccaactatgg tcattgttgc acaataattg tgcggatata aaacttacac
     7921 tttcaattaa agaaggagac gttaattatg agtaaaatta tcggtattga cttaggtacg
     7981 actaactctg cagtagcagt attggaagga aacgaagcaa aaatcatcgc taacccagaa
     8041 ggaaaccgta caacaccttc tgttgtatca ttcaaaaatg gagaaatcca agtaggggaa
     8101 gttgcaaaac gtcaagctgt gacaaaccca aatacgattt catcaatcaa acgccatatc
     8161 ggtgaagcag gttacaaagt agatgtagaa ggtaaatcat atacaccaca agaaatctca
     8221 gcaatgatcc ttcaatatat caaaggattc gcagaagact atttaggtga aaaagtcgaa
     8281 aaagcagtta tcactgtgcc agcttacttt aatgatgcac aacgtcaagc aacaaaagat
     8341 gctggtaaga tcgctggtct agaagtagaa cgtatcgtca atgaaccaac tgcagctgct
     8401 cttgcctatg gtttagataa aacagatcgc gacgaaaaaa tcttagtatt cgaccttggt
     8461 ggcggtactt ttgacgtatc tatccttgaa ctaggagacg gtgtctttga tgtattgtca
     8521 acagctggcg acaaccatct aggtggggac gactttgata acaaaatcat cgactacatg
     8581 gtagcagaat tcaaaaaaga aaacagcatt gacttgtctc aagacaaaat ggctttacaa
     8641 cgcttgaaag acgctgctga aaaagcgaaa aaagatttat ctggcgtatc aagcacacaa
     8701 atcagcttgc catttatcac agcaggagaa tctggaccat tgcatttgga aatgacattg
     8761 acacgtgcaa aatttgatga attaacagct gacttagtag aacgtacaaa agtaccagta
     8821 cgtcaagcgt taaaagatgc aggtctgtca caatcagaaa tcgacgaagt tattttagtc
     8881 ggtggatcta ctcgtatccc tgcagttgta gaagcagtac gtaaagaaac aggaaaagaa
     8941 ccaaacaaat cagttaaccc tgatgaagta gttgctatgg gtgctgctat ccaaggtggc
     9001 gtgatcactg gtgatgtgaa agatgttgtt ttacttgacg ttacaccatt gtcattaggt
     9061 atcgaaacaa tgggtggagt gttcactaaa ttgattgacc gcaatacaac gattccaaca
     9121 agtaaatcac aagtattctc aactgcggca gataatcaac cagcagtaga catccatgta
     9181 ttacaaggtg aacgcccaat ggctgctgac aacaaaactc taggaagatt ccaattgaca
     9241 gatattccag cagctcctcg tggtattcca caaatcgaag taacattcga tattgataaa
     9301 aacgggattg taaatgtatc tgcgaaagat ctaggtacac aaaaagaaca aaaaatcacg
     9361 atcaaatctt cttcaggtct aacagacgaa gaaatcgaac gtatggtgaa agatgcagaa
     9421 gcaaacgctg aagcagataa agctcgtaaa gaggaagttg acctacgtaa tgatgtagac
     9481 gcattgctat tctctgtgga caaaacattg aaagaattag aaggcaaagt ggacgaagaa
     9541 gaagtgaaaa aagcagaaac agctcgtgac gaattaaaag ccgctgttga agcaaacaac
     9601 atcgaggaaa tgaaaactaa acgcgatgca ttgaacgaaa tcgttcaaaa cttgactgtt
     9661 aaactatacg aacaagctgc acaacaacaa gctcaagaaa atccagaagc agctcaaggc
     9721 ggagcagatg atgtcgttga tgctgatttt gaagaagtcg atggcgacga taaataatca
     9781 gttcactgaa tttcgagaga aggccaaagt tgctactttg gctttttctt ttgaaaaata
     9841 gtttgaagta tcggtttttg tttcaaacaa aatatgatat gataacaagc gacgtgaaaa
     9901 tgatgagaac caataggagg aaagcctatg gcaacaaaac gtgattatta tgaagtctta
     9961 gggctctcaa aaggagcatc agaagatgaa ataaagaaag cttatcgtaa gctttcgaaa
    10021 aaataccatc ctgacatcaa taaagaacct gatgcggaag aaaaattcaa agaagtatca
    10081 gaagcatatg agattttaag tgacccgcaa aaacgcgctg catacgacca atacgggcat
    10141 gcaggcacag atccaaatta cggtgctggt ggagctggtg gcggatttgg tggattcggc
    10201 ggcttctctg gtggcggctt cggtggtttt gaagatatct tcgactcttt ctttggagga
    10261 ggcggtcggt cagtcgatcc aaatgcgcct cgtcaaggtg ctgatttgca atatacggtc
    10321 gacttgtctt ttgaagaagc gatttttggt gtagaaaaag aaatcaagta taatcgggaa
    10381 gaaatctgtc atacttgtgg tggaaacggt gcaaaaccag gcacacaacc aactacttgt
    10441 cataaatgtc atggtgcagg tacgatcaat gtagaacgcc aaacgccact tggacgagtg
    10501 atgagccgtc aaacttgtga tgtttgtcat ggcacaggga aagaaatcaa agaaccttgt
    10561 ccaacctgtc atggctcagg acatgagaag aaagcacatt cagttaaagt gaatgtacca
    10621 gctggtgtag aagaaggaca acaaatgcgt ttagctggtc aaggagaagc tggagaaaac
    10681 ggcggaccat ttggtgattt gtatgtggtt tttcgtgtag aagaaagtga tatctttgat
    10741 cgtgaaggtt ctgaaattta ctatgaattg cctttaagtt ttgtacaagc agctttgggg
    10801 gatgaagtcc aagtaccaac tgtccatgga gatgtgaaat tgaagatccc tgctggaaca
    10861 cagacaggta cgaacttccg tttacgtgga aaaggcgctc cgaagttacg tggtggtgca
    10921 acaggcgacc aacatgtcaa agtaaaactg atcacaccga aaaatctaaa tgaacaacaa
    10981 agagaagcat tacgtgcatt cgctgaagct ggcggcatca aagttgaaga acagcaagaa
    11041 gacggtttct tcgataagtt taaagatgct tttggcggga aaaagcggaa gtagtttttc
    11101 tagtaaaaat ataaagtaga cttgcccaaa ttttctattt ctagtaaaaa cgctaagtca
    11161 ttaataatta aaaaccagac gaacaatcat acgttcgcct ggtttttttg tagttgtcat
    11221 gtttgtacca acaaaaaagc cagctttaga ataagataat catcatagtt tctgaaggtg
    11281 gtatcgacta tgtacttgat atcgtcaatg aaccgatggt actttcttat gcgatggaac
    11341 aggtagagcg attgcttgtt tgtgcaggag aacaagcgat gcggctggta cagttaagtg
    11401 aaaaaacaag aaactaaaaa tgcccggtcg tcatgaagcg accgggcatt tttggttttt
    11461 attaaatatt taatacttta ttcaagaaat cttttgtccg ttcattttgc ggattttcaa
    11521 agatttgttg aggcgttccg tcttctaaaa agtttccgtc gtcaatgaac atgacacgat
    11581 tggccacttc tttagcgaag cccatttcgt gcgtaacgat aaccatcgtc ataccttgtt
    11641 ctgctaactt tttcatgacg ttcaagacat caccgaccat ttcggggtcg agtgcagatg
    11701 taggctcatc aaaaagcatg atgtcagggt tcatcgctag agcacgagca atagccacac
    11761 gctgcttttg tccaccggaa agcatttcag gatacatatc ttttttatct tctagaccaa
    11821 ctgtctgcag caatttgatt gcttttttct ctgcttcttc tctagattct ttcttcaggt
    11881 ccatcggtgc taaaatgatg ttttccaaaa tagaaagatg agggaatagg ttaaagtgct
    11941 ggaataccat tccgatatgt tgtctcacca agttgatatc tgtgctttta tccatcaagt
    12001 gggcgccgtc aataataatt tcaccgtcag aaggttcttc taaacgattc aagcaacgca
    12061 aaaatgtact ttttcctgaa cctgaagggc caatgataca gacgacatct ccttcgttga
    12121 tggacacatt gatgtcgttt aatactgtgt tatcgccgta ttttttgact aaatgctcaa
    12181 ctaagatttt ttctgccatc ttacttcacc ttcttttcta aaacttttgc taattttgtc
    12241 aatgctgtga tcaaaatcaa gtacatgatc gcaatgatca agtaaacata cgtactttgt
    12301 gttgtacgtg caacaatgat cttaccagtt tgcagcaatt cgactacacc gattgcggaa
    12361 atgatcgttg tgtcttttaa tgagataacg aactgattga cgaatgatgg gatcatgatg
    12421 cgtatcgctt gcggcaaaat gattttttgc attgtccgat tataagaaag acctaaactt
    12481 ctggaagctt ccatttgtcc gacaggaacg gcgttgatcc cgcctcgaac aatctctgcg
    12541 atataagcac ttgcgttaag agtcaaggtg ataacaccag caaggaagtc aggaatcgta
    12601 aatccaacga taccaggcaa cccaaagaaa ataaagaacg caagaaccat cattggaatt
    12661 cctcggatga tatcgacata aatactagca attgtgcgaa gagcgcgtat tggtgctaca
    12721 ctgaataatc caaaaatcac accgattact atagccaaag caaaggagat caaagttagg
    12781 agaattgttc tccaaagtcc tttcaacaat gcttgatagt tgttttggat aagtccaaga
    12841 aatgttgatt catcagcagt ggaagactca ctggaagttt ctgaaccatc cgctacatat
    12901 tctttaataa tcttatcgta ttcgcctgtt ctttttaatt ctttcaatcc ttcattgaac
    12961 atattaagaa gctcaggatt ttgtcctttt ttaacggcaa atgcatattt tccgccagat
    13021 tcttttttga tcggtgtttc caattcttgt ccttgtttga tcgcataacc gattaccgga
    13081 taatcatcca tcattgcatc gattgcgcca acttttaacc cgtcgtacaa ttgatcagca
    13141 gcatcaaaat atttgataga atagccatat tcagattcat ggtcgcttaa aaattcagca
    13201 ctttcggtac caacttttgc tccgactgtt tttcctttca aatcttcata agacttgatc
    13261 gaagtatctc cttttttgac agctaattgg atcccgctat caaagtaaga atcagaaaaa
    13321 tcatagcttt tctttcgttc atctgttaca gtcattccgg caatcattcc gtctgcttgt
    13381 cctgattcca aagcttgcaa agcagcagag aaaccacggt agtccattcg gatgttaaat
    13441 ccttgcagtt tggcgatgtt ttccatcaat tttacatcga tgccttcgta ctcgcccttt
    13501 gcgttttgaa attcaaatgg agcaaaagca gagtcactgg caattacgta tacgtctttt
    13561 ttgggctcta ttttttgcat tgtctcgctt gtgcttgact ctgccgttgt agtgttgtca
    13621 gcttgtgcaa catgtccaaa cgcaagtgtc acaagtcctg tcattaagaa aacaaatgag
    13681 tgaaataaat gctttctttt cataatcaac ctcctaaatt tccaatattt tattattata
    13741 ggcgaaaagt gctgaatcag acaagactgt aagctcgaaa aaatgaaaaa aatgcgagtt
    13801 tctaacattt tatgttataa aacgtaacat gcataataag ataaaaaagt ggcgaaagta
    13861 tgttcggtgt ggtataattt tttagtaagg aatgcctttg ctttcctttt ctttttattg
    13921 gtcgtaaaat gaaaaggaat gaatgaaaag gaggacgaag aatgattgag agagatacct
    13981 cccgacactt tgagcttgtc tcgaaatacc aaccggctgg tgatcagcct gaagcgatta
    14041 accaattagt ggatggcgta gtcggcggga aaaaagcaca aatcttatta ggtgcgactg
    14101 gaacagggaa aacatatacg atttccaatc ttattgagaa agtgaataaa ccaacactaa
    14161 ttattgccca taacaaaaca ttggctggtc agctgtacgg ggaattcaag gaatttttcc
    14221 ctaacaatgc tgttgaatat tttgtttctt attatgatta ttatcagcct gaagcttatg
    14281 tgccttcaag cgatacgtat atcgaaaaag attcaagtgt aaatgatgag atcgacaaat
    14341 tacgacattc ggctactagt tcattattag aaagaaatga tgtgatcgtc attgcatccg
    14401 tttcatgtat ttttggatta ggttcgcctt ttgagtacca aaaacaagta gtttcgattc
    14461 gacagggagc agaactagat cgcaatcagt tgattcgtga cttagtcagt atccaattcg
    14521 aaagaaatga tatagatttt cagcgcggtc gttttcgagt gcgcggtgat gtcgtggaga
    14581 tttttccggc ttcaagagat gaacgtgcct tacgtgtgga gttttttgga gatgaggtcg
    14641 aacgtatccg agaagtcaat gcactgacag gtgaagtttt aggagaaacg gaacacgtgg
    14701 caatcttccc ggcgactcac tttgtgacga atgatgaaca tatggagcat gccgtagcga
    14761 atatcaaagc ggaattagaa cagcgtttaa ctgtcttgcg aaatgaaaac aaacttctgg
    14821 aagctcaacg tttagaacag cgaaccaatt acgatattga aatgatgtta gaaatgggct
    14881 acacgtcggg aattgaaaat tattctcggc atatggacgg acgtaaagaa ggtgaaccgc
    14941 cttatacgct attggatttc tttcctgaag attttttgat cgtggcggac gaatcgcacg
    15001 taaccatgcc tcaagtcaga ggaatgtata atggtgaccg agcgagaaaa cagatgctag
    15061 tagattacgg tttccgtttg ccatctgctt tagacaatcg gccacttcgg ttagaagagt
    15121 ttgaaaaaca tgtcaatcag atcatttatg tctctgcgac gccaggacca tatgaacatg
    15181 aacaaacaga taccgttatc caacaaatca tccgtccgac agggctgctt gacccagtga
    15241 tcgaagttcg tccaatcatg ggacaaatcg atgatctagt aggcgaaata aatgaacgag
    15301 tcgaaaaaga ccagcgggtg tttgtaacga cattgacgaa aaaaatggca gaagacctca
    15361 cagattattt caaagaatta gggatcaaag tcaaatattt gcatagtgat atcaaaacgc
    15421 tggaacgaac agaaatcatt cgagatcttc gattaggtga atttgatgtg ttagttggaa
    15481 tcaatttgct tcgtgaagga ttagacgtac ctgaagtttc ccttgttgct atcttggatg
    15541 cggataaaga aggcttttta cgtagtgaac gttccttagt ccaaacgatt ggacgagctg
    15601 ctcggaatga agaaggtaaa gtaatcatgt acgcagacaa agtaacagat tctatgcgtc
    15661 tagcgatgga tgaaacatca agacgccgta cgattcagca gaagtacaat gaagaacatg
    15721 ggatcgttcc aaaaacgatc attaaagaaa tccgagattt gatttctatt acgaaagaat
    15781 cggaagatga tacaaaagaa gcggtacaag tctcgtatga agaaatgacg aaagaagaaa
    15841 aagatacgtt attgatgaaa ttagaaaaag aaatgaaaaa tgcggcgaaa gcattggatt
    15901 ttgaaacagc cgctaatgtg cgagatatga ttttagaatt aaaagcttca aagtaggagg
    15961 acaacatggc taacgataaa attacgattc acggtgcacg tgcccataac ttgaaaaata
    16021 tagatgtaac gattccacga gataaattcg tggtcgttac aggtttgtcc ggttctggaa
    16081 aaagttccct agcatttgat acgctgtacg ctgaagggca gcggagatac gtagagagcc
    16141 tttctgctta tgctcgtcag tttttaggac aaatggataa gccggacgta gatagcatcg
    16201 acggattgag tccggcgatt tctattgatc agaaaacaac aagtaaaaat cctcggtcga
    16261 cagtaggtac tgtgacggaa atcaatgact atttacgctt gttgtttgca cgtgtaggac
    16321 atccgatttg tcccaacgat catatcgaga ttaccagtca atcagtagat caaatggcag
    16381 atcaagtaat ggctttgcct gagcgcacaa agatccaagt gttggcaccg atcgtggtaa
    16441 agaaaaaagg acaacataaa aaaatattcg aacgaatcca aaaagaggga tacgtccgcg
    16501 ttcgagtcga tggtgagatc tatgatttaa gtgaagtgcc tgagctggag aaaaacaaaa
    16561 aacatgatat cgcgatcgtc atcgaccgga tcattgtgaa agaagggatt cgttctcgtc
    16621 tatttgattc tttagaggcg gctctgcgat tggcagacgg ctatgctctg gttgacgtga
    16681 tcggtgaaga agaaatgttg tttagcgaac actatgcctg tccttattgc ggatttactg
    16741 ttggcgaact agaaccaaga ctgttctcat tcaatgcgcc ttttggagct tgtccagact
    16801 gtgatggttt aggtgtcaaa ttagaagtcg atcaagattt agtgattcca gatagaacga
    16861 agacacttag tcaaggtgct atcgttccat ggaatccaat cagctctcag tattatcctc
    16921 aaatgttagc gcaggcttgt gaaagtttcg gtatcgattt agatacacca ttcgaagaat
    16981 taccggaaga gcatcaggat atcatcttga atgggacaga tgatcttttc catttccatt
    17041 atgaaaatga ttttggtggc gttcgcgatg tagaaacgac tttcgaaggg gtattgaaga
    17101 atatcgagcg tcgttatcat gatacgaaca gtgatttcac gcgtgagcaa atgcgtcttt
    17161 atatgacaga attaacttgt cagacatgta aaggttatcg attgaatccc caagctctat
    17221 ctgttcaaat caatggaacg aatatcgggc aaacaaatga gttgtctatt caaaaagcag
    17281 tagatttctt ctcaaactta acgttatctg aacaagagaa agtaattgcc aaaccgattt
    17341 taaaagaagt aaatgacaga ctttcattct tggaaaatgt gggactagac tatctaactt
    17401 tgagtcgcgc ttccggaaca ttatctgggg gagaagcgca gcgaatcaga ttggctacac
    17461 aaattggatc gaatctttct ggagttttgt atattttaga tgaaccatcg atcggattgc
    17521 atcaacgcga caacgatcga ctgattggct cattaaagaa aatgcgtgat cttggcaaca
    17581 ccctcgttgt agtcgaacat gatgaagata cgatgtgggc agcagattat ctgattgacg
    17641 tcggacctgg ggccggagaa caaggcggac aaatcgtggc tgcaggcact cctgaagaag
    17701 tagctaatga tgaaaattct ttgacaggga aatatctttc agggaaaaaa tcaatccctg
    17761 taccaaaaga acgccgtaaa ggtaatggga aagcaatcaa gatcactggt gcttcagaaa
    17821 acaatctgaa aaatattagt gttgaatttc cattaggaga atttgtagca gtcacaggtg
    17881 tgtctggttc tggaaagagt acattggtca atagtatctt aaagaaatcg ttagcgcaaa
    17941 aattaaataa gaattctgct aagccaggta aattcaagac aatttccggc tacgaaagta
    18001 tcgaaaagat catcgatatc gatcaaagcc caatcggccg gacgccgaga agtaatccag
    18061 cgacttatac aagtgtattt gatgatatcc gtgggttatt tgctcaaacg aacgaggcaa
    18121 aaatgcgggg ttataagaaa gggcgtttta gtttcaacgt aaaaggcggt cgttgtgaag
    18181 cttgtcgcgg ggatggaatt attaagatcg aaatgcactt tttgcctgat gtctatgttc
    18241 cttgtgaagt atgtcatggc aaacgatata actctgaaac attagaagtg cattacaaag
    18301 gaaaaagcat tgctgatatt ttggaaatga cagtagaaga tgctgtagaa ttcttcaagc
    18361 acattccaaa gattcatcgc aaactgcaaa cgattgttga tgttggctta ggttatgtga
    18421 cgatggggca accagcaacg acattgtccg gtggtgaggc acaacggatg aaacttgcca
    18481 gtgaattgca caaaatctct aatggaaaga atttctatat actagatgaa ccaacgacag
    18541 gacttcatag cgatgacatc gcccgcttgt tgcatgtatt acaaagatta gtagatgctg
    18601 gtaacacagt tttagtgatt gaacacaatc tagatgtaat caaaacagca gattatatca
    18661 ttgatttagg accagaaggt ggagaaggtg gaggaacgat ccttgcgact ggaacaccag
    18721 aagaaatcat taacgtaaaa gaaagttata caggtcacta tttgaaaaaa ataatggtat
    18781 aaagaggata gatagctgag atagttaaaa aaacataaaa aaatgaattt ttgcttgttt
    18841 tattaatatc agtgttctag aatcattaca tggtagttct ttctacactg attggtatag
    18901 acaaaaactt cctataagtt caatccgttc aaaaaagaat tgagcaatcg gaggagtttc
    18961 ctttgattgc ttttttcttt atggtatgat attccttgtg tagttggaaa agaaaaacaa
    19021 gagattatga gtaagtgaga gataatgatg aacagtattg aaaatgaaga atttatccct
    19081 atattattag gaagcgacat gaacgtttat ggtatggcac gttcttttaa tgaagcatac
    19141 ggcaaaatct gccaagcata tgcttcggat cagttagccc ctacccgcta cagtaaaatt
    19201 gtcaatgtag aagttattcc aggatttgat aaagaccctg tgtttatcga gacgatgctt
    19261 cgtttggcaa aagaaagata ttctgataag agtaaaaaat atcttttgat tgcttgtggt
    19321 gatggatatg cagaattgat ctcccaacat aaacaagagc tgtcagaata ttttatctgt
    19381 ccatatattg attattcttt atttgaaaga ctgatcaata aagtaagctt ttatgaagtt
    19441 tgtgaagaat atgatcttcc gtatcctaaa acattgatcg tcagagaaga aatgttagta
    19501 aatggacatt tggaacagga attgcctttt gaattcccag ttgctttgaa acctgcaaac
    19561 agtgtggagt atctttctgt ccaatttgaa ggaagaaaaa aagcttttat tttagagact
    19621 agagaagagt tcgatttaat tttaggccgg atatacgaag ccggttataa aagtgaaatg
    19681 attgtacaag attttatccc gggtgatgat agtaatatgc gtgtgctaaa tgcgtatgta
    19741 gatgaagatc atcaagttcg gatgatgtgt cttggtcatc cactgttaga agatcctaca
    19801 ccagcatcga ttggtaatta cgttgtgatc atgccagatt ataacgaaaa aatctatcaa
    19861 accattaagg catttttgga aaaaatcgaa tatacaggct ttgccaattt cgatatgaag
    19921 tatgatccta gagatggaga atataaatta tttgaaatca atttgagaca aggtcgtagc
    19981 agtttctttg tgacattgaa cggcttgaat ctggctcgtt tcgtcacaga agatcgagtg
    20041 tttaacaaac cctttgttga aacgacctat ggaacgaatc aatcagataa agcaagatta
    20101 tggatgggtg tgcccaaaaa aatcttttta gaatatgctc gggaaaatga agacaaaaaa
    20161 ctagctgagc aaatgatcaa agaaaatcgt tacggtacta ctgtgtttta tgaaaaagac
    20221 cggtcaatca agcgctggtt gttgatgaaa tatatgttcc ataactatat tccaagattc
    20281 aaaaagtatt ttcatgtgaa agaaggctag ttcatggaga attttttcag tattttaggc
    20341 ggaatgggca cgatggcgac agaaagtttt gttcgcttga tcaaccaccg aacgaaagct
    20401 acaaaagatc aagaatattt gaattatgtc ttattcaatc atgcaacagt tcctgatcgt
    20461 acagcttata ttttagatcg atcagaagaa aatccaatgc cgtttctgct ggatgatatt
    20521 gagaaacaaa atttattgca gccgaacttc attgtgttga cttgtaacac cgcacactac
    20581 ttttttgaag aattacaagc ggcaacggat attcctatcc ttcatatgcc aagagaagca
    20641 gcaaatgaac ttgtccgtca gcatacgaca gggagagtag cgattctagg aacagaagga
    20701 agtatgaaag ctggaatcta tgaacgcgaa gtcaaaaatc ttggattcga aacagtgatt
    20761 cctgatactg ttcttcaaga aaaaatcaat tatctgatct atcatgagat caaggaatcg
    20821 gattatttga atcaagagct atattacgaa atcttagaag aagcggtaga gcgcctaaac
    20881 tgtgaaaaag ttatcttagg ttgcacagaa ttgtcattga tgcatgaatt tgctgaagat
    20941 aaccattatc cagtgatcga tgcccaatct attttagcag atcggacgat tgaacgagcg
    21001 ctagctgaaa gaagcaaggc attggataca gcatcggaaa agtaaaaaaa ttggatttgg
    21061 ggcaaatatc ctaaaagata tttggtccaa atctttttgt aaaagaaaaa gaaaactggt
    21121 aatgatacgc ccggaatgat ataattttac tatgcacaat gtgagaggag ttcgtaatta
    21181 tgacagataa tttgcaatta gtcatcataa caggtatgag cggtgcaggg aaaacagtag
    21241 ctatccaaag ttttgaagat atgggctatt tttgtatcga taatatgccg cctcgattga
    21301 ttccaaaatt ctgggaatta atcaaagaat caggcaaagt cacaaaaatg gctttaggag
    21361 tggatttacg ttctcgttcc ttctttgaag aaatccaaaa catgctgatc gaaatcgaaa
    21421 atacgaactt catcgacact tctatcttat ttttagatgc ttcagacgaa gaactagtgg
    21481 ctcgctacaa agaaacaaga cgagcacatc caatggcgat ggacggtttg atcactgaag
    21541 ggatacgtaa agaacgggcg atactagacg acttgaaagc ccaagcttcc gtgatcattg
    21601 atacgacgac attgacacca cgacaattac gtgaaaaaat caatgagtca ttcaaatcaa
    21661 agggagacca aggatttcgg atcgaatttg tatcatttgg ttttaaatac gggttgccga
    21721 tcgattcgga tattgtgatg gatgtgcgtt ttttgcccaa ccctcattat atcccggaac
    21781 taagaccatt gaccggaaaa gatcagccag tctatgatta tgtgatgtcc tttgatgaaa
    21841 cgcaatcatt ctaccataaa tttttggatc ttctggaaac tgtattgcct ggatacatta
    21901 aagaaggaaa aagcagcttg acagttgcaa tcggctgtac aggcggtcaa caccgttctg
    21961 tggcattgac tgaacgtttg gcaaatgctt tagggaaaaa ctataaagtc aatgtgacac
    22021 atcgggacaa ggataaaagg aaagagacgg tgaaccggtc gtgaaaatga aaacctaccg
    22081 gataagaaaa ccaaagatcg tagtggtcgg cggtggcact ggtctgccag ttatcctgaa
    22141 aagtttgcga aatcaaggag cagatatcac agcagtagtg actgttgcag atgatggggg
    22201 aagcagcggt gcaatcagag aatcgatcgc tatggctcct cctggtgact tgagaaatgt
    22261 cttagtggcg ttatcggata tgccacaatt ctatgaagat attttccaat accgtttcaa
    22321 aaaggaagat cagtttttag ccaatcatac gatcggtaat ctgatcattg ccgcagtttc
    22381 cgagatgcgg ggaagcactt atgaggcgat tcaattatta gcaaaaatga tgcatgtaga
    22441 tggacatgtt tatccttctt cagaaactcc tttgaccttg catgctgtct ttaaagacgg
    22501 aacgactgca gtaggagaat ctaaaatcgc gatcgaccgt aaaaccattg accgtgtgta
    22561 tgtctgcaac acaaatgata aaagtgaagc caaagcggct cgaaaagtcg tttcagcaat
    22621 tatggacgcc gacatggtcg ttttgggacc cggaagttta ttcaccagta tccttccaaa
    22681 tttagtgata ccagaaatcg gcgaagcaat gctcaagaca actgctgaaa ccgtctatat
    22741 ctgtaatatc atgacccaaa aaggggaaac ggaacatttc acagatgccg atcatatacg
    22801 tgttttacac aagcatttga atcagccttt tatcgataca gtattggtca atacggaaaa
    22861 agtgcctgaa gattatatgg acccagagat ctatgatgag tatctagtac aagtcgcaca
    22921 cgacttcaac ggattgagaa atgaaggatg tcgagtgatt tccaccgact ttttggaatt
    22981 gaaagatggt ggtgtcttcc acgatggaga caaagtagta gaagaattgt tccgtttagt
    23041 tttcggttca aaatattaag caatttattg ttggagaaag gaggagaata ggatgtcatt
    23101 tgctgcagat gtgaagaaag aactaactgg tttggaagtt catcgagaac atgcgaaagc
    23161 ggaattagct gctttgctgc gaatgaacgg ctctttaggt attgtgaacc agcagtttat
    23221 tttgaacgtc caaacagaaa atgctgcaat tgccagacgt atctattctc ttttgaaaga
    23281 tcattatcag gtacgaagtg agctactcgt tcgtaaaaaa atgaaattaa aaaagaacaa
    23341 tgtctatatc gtccggttga agcaaggcac aaaagatgtg ttgatggatc ttgatatcat
    23401 ggatggtatg atgttcaatg gacacgtttc ggacgagatt atgggaaatt cgcaaaaaat
    23461 gcgttcttac ttacgtggtg cttttatggc ctcaggttca gtcaataatc cggaaacgag
    23521 ccgttatcat ttggaaatat tttctattta tgaacagcat aaccaagaca tttgcgatat
    23581 gttaaattat tacggtctac atgctcgaac gcttgaacgg cgcaatggct atatttctta
    23641 tttaaaagga gcagaaaaaa ttgctgattt cttaacattg attggtgcaa ccaactcaat
    23701 gctccgattt gaagatgttc gaatcgtacg ggatatgaga aattcggtca atcgtctagt
    23761 caattgtgag acagcaaatc tgaacaagac gattgatgcg gcttctaaac aaatcgaaaa
    23821 catcgaattg atcgaagcaa aggtcggtct acatgccctt cctgaaaaac ttcaggaaat
    23881 cgcagaactt cggcttcaac atccagaggt cagcttgaaa gaattagggg aaatgattcc
    23941 ctcaggtgcg atatcaaaat cgggaattaa tcaccgaatt cgcaaaataa atgaatttgc
    24001 ggaaaaactg cgtgaagaag cagtttaatc caaagaaaaa actgatacat gaagcaggag
    24061 atgcgaatgt atcagttttt tttaaaagtt atacttgctt ttcttccgtc aaactataat
    24121 tccatcttta ctggagtaac ataatttgga aaggcttcta ttgtttttaa tacaatcgta
    24181 taaaaagcgg ggagacaact gaatgaagat tttagttttg tacataaatt tttgcttaat
    24241 atagaagtcc tgatatagat aagatcaagt atttatctat aactggcctg attaattaaa
    24301 aaactggaag gaactgctcg atcatccttg agaactgctc ttcttacttc tggtcaagat
    24361 tctcgtggtt ggtggataag gatggttgat aagttcattg gattagctag tcgaaaacaa
    24421 ccaggtgtaa ttaatgtaga agttttaaca aggggatgga gtgatttatt cagtgataat
    24481 cataagttca taaatagtaa ttgagatgta tggttggaat acgttatacc tgaacttgaa
    24541 ctaccaagat ttggtttaga atttgagaat cgatgtttat aaagggaggg caaaaatgcg
    24601 tttttttaca acttttacta tcattatgat tgcagtactt tttatttttc tagatatagc
    24661 aaagcgaaat acagcatttt tattatatcg ggttttactt cgagcaggtc tcataacatt
    24721 tatatcgatc gttggatttt ttctattcac agttattgta tttatttgga gaactccagc
    24781 accaccattg ccagagatta catatggaga atttcctttt agacttgagt atgaattgaa
    24841 tgaagaatta catgtgatag aagacacgtt aatagttgaa tttgatggat ttggaatgaa
    24901 cgaaggcata gggagatatc gtagatggac aagtcgttta gccagcggag aagatttagt
    24961 gttgctgtta gaagttagtg ataataagca aatattttat tttccaggac ctgctaatta
    25021 ttacatggga gataggttga atggttataa tcatactttt cctagtgctt ctttcattga
    25081 aagggaaaga ggcattacta gaagggatat tttacatgac aaagaattat tagaacaatt
    25141 tggtccgctt gatcaaaata caataaatga agaagaattg ttaaatcaat ataatataag
    25201 gctagtgaat tgggaaatat ctgaaccgat tgttaacaat tttggtgatt agaaaacaat
    25261 tacgataaat agaaacaagc caaatcatca gcaagtaaaa gctgatgatt tggcctttct
    25321 tatacgagta gtaggaattc atagcgaata ttattacgat cagtagatat tttgatatta
    25381 aaggagtatt acgaactagt atgtgagaat gtagaggtga tttgcgaata atgagaaatt
    25441 tatcaaatag aaacaaaata ttaatcatta ttgttgttat agctgtgttt catctgggaa
    25501 cgaatgcggt tttaagtaga ataatattgg gtcctaagcc accaagacct gcgattaccc
    25561 gaggggagtt tgattttaga ttagaatatg aagtagatgg ggaaaggatt gtgatagaag
    25621 atacaattgt tgcattattt gatggatttt ctgcagatgc aggtagcatg gcatggtatc
    25681 gcacgtggcg tttgcatttg gcgagtgaca agagggcaca acaattattg ttacatgagt
    25741 tagatgatgg tcgaaaaata tattatcatt ttggaggagc tggattttat atggggaagt
    25801 tagtagcagt gtaactgtaa caaggaaaga tttgccaggt cttggcattc gaaactccat
    25861 attttatatc gagcgtggga gagatacatc tattgggaac aggaaagggt taactcttga
    25921 agagttatat aatgactttg gaatccgtct tgttagttgg gaacacaatc caccaataga
    25981 aaatcgcttt gaataatcga aatctattaa tccatttcat cagccagtga atgttgtaat
    26041 ggaacaattt ggtttagtgt tcaaaaccat tgaaatacta ggctgtgatc agcaaaaatg
    26101 tatctgaata aaaaagagag caactattaa atgagaggag ttaggagttg ttagctttat
    26161 acgaatcaaa gtggcaaata cagatgcgta tgcatttgtg tttgccatct tgcgtttggt
    26221 agacgagata ggtataagct aaagaaacaa cttgtttaaa ataaacgacc tagctcaaca
    26281 aacgaccatc taatcaacta acagcataca taaaagcaac tatttttgaa gtagaattga
    26341 aatcgggata acttaaaaag tgattgggat actagtgtga atcaccgtac ataaatatta
    26401 ctcgttaagg gaatttgaga aattttgtat gaaaatttaa gaattagtta gtatgcgcaa
    26461 gtcaaaaata tgaataaatt atttggtgga gataatttgc tcagcttgtc ataagaaatg
    26521 agataatctg gcagatgcaa gcttttggac accatttatt cggaataagg aggctgggac
    26581 agaagcgttt aactccaaga aataagaagg agttgcttct gcttccgccg tttataggtg
    26641 tttagagcgt gagacaaaag tgttctttac ttttgtccta cgctccttat ttttttattt
    26701 tgtttggatc aattctttta attcctctat tgaaatagat tcatcaaaga tttctttacc
    26761 caagatgaca gtcggaacaa atcgaatatg tgcttgctca gcttcgttga tgacagcttg
    26821 gctcagctgt tcgtcttttt gttctgtcag ctttagttta tctactgcaa aatccgctac
    26881 ttcttggaga gaaagatgtt tccactcgtc ttgagtatcg aatatttgtt tgatctcttt
    26941 gatcgctttt tgaccatcgc tgattgtgag ataccggtgc atcacgtttc ctcgctgcaa
    27001 gctttctttt tctttatcga acaatttgat cactcgctgc aattgcccgc tttggactgc
    27061 ttcttctaat agctcataag attcttcaaa ccattgtcgg caatacggac aagataggtt
    27121 gatgaattcg accatttttt taggagcatt cgatgaacca taaaggattc ctttttgtgt
    27181 atttgttttc gttgcatcaa tcactgatat atccatgtta aaacacctct ttcgcttata
    27241 gtttatacat gtctgacaaa aaaaggcaac gatttagact gtttgtctaa aaattagatg
    27301 accaattcaa atagacatat gtgaaatatt tttataaata aaagaaaaaa tggaatgttt
    27361 tacgttataa tggaacagat aataagagag aatatgaaca aggatgatga atcatgcgaa
    27421 aaatgaaaac aatggatggc aatacggcag ccgcatatat ttcttatgca tttaccgaga
    27481 ttgctgcaat atatccaata acacccagtt cgaccatggc tgaattagta gatcaatggt
    27541 cagcagcagg aaaagaaaat gtattcggtc aaccagtaaa agtagtagaa atgcaatccg
    27601 aagcaggagc agctggtgtg gtccatggat cattgaaaac tggtgcactg acaactacat
    27661 ataccgcttc tcaagggctg cttttgatga taccgaatat gtacaagatt gctggggaac
    27721 tactgccaag tgttttccat gttgctagtc gggcagtgac gacaaatgcg ttgaatattt
    27781 tcggagatca cggagacgtg atggctgcaa gacaaacagg atttgctatg ttagctgaaa
    27841 gcagtgtaca agaagtgatg gatttagcac ctgttgccca tcttgcttct attgaaggag
    27901 aagtaccttt tttgaatttc tttgatggat tccgtacgag tcacgagatt caaaaaatcg
    27961 aagttttgga atatgaagaa ttagctcctc tgatcaatca ggagaaatta gcttcatttc
    28021 gtaaacgagg gatgaatccc aatcatccga ctgttagtgg tacgaaccag aatccagaca
    28081 tccattttca acaacgggaa acgatcaacc cctattatga taaattacct gaaatcgttc
    28141 aaaaatatat gaaagagatc aaccgattac gaggaacttc ttatgacttg gtgacttatt
    28201 acggagcaga cgatgcggaa gaagtcattg tttctatggg atcagttgca cagacgattg
    28261 aacaaacgat tgattacttg aatgcaaacg gacggaaaac aggttttttg aatatccatc
    28321 tttatcgtcc ttttccagtg gaaacattcg tgcaaaagtt gcctcataca gtaaaaacaa
    28381 ttgctgttct tgatcgaagt aaagaaccag gggcaggtgg agaacctctc ttattagacg
    28441 ttcaaagtgc gttatatgat tctgaacttc gcccggctgt tattggtggt cgctacggat
    28501 tggggtctaa agatgtgact cccgaccaaa tctcagcagt ttttgatgaa ttgaaaaaag
    28561 acccaagcat acgcaaaaaa cggtttacca tagggatcgt ggatgatgtg acttatcaat
    28621 ctttggaacc aaaggaaagt ctggatttga cagaaccgca aacattccag gccaagtttt
    28681 ggggatttgg atctgacgga acagttggag caaataaatc agctatcaag attattggag
    28741 atcacaccga taaatatgcg caaggctatt tttattatga ttcgaaaaaa tctggcggtc
    28801 tgactgtctc tcatcttcgt tttggagata cgccgatacg ttcagcgtat cttgtcgagc
    28861 atgcggacct tgttgcctgt cacacaccag cttacctgca tagctatgac ttggtcaaag
    28921 gattgaagcc aggtggcatt tttttattga atactctttg gagcgacgaa caattagaaa
    28981 cgcatctgcc cttaaaatta aaacgttact tggctgaaaa taacattaga ttctatacga
    29041 tcaatgccat gagattggcc caagaagtcg gtttgggacg ccggatcaat acggcaatgg
    29101 aaacggcttt ttttaaatta gctgacatca ttccttttga tgaggtgctt ccgctgctaa
    29161 aagaagaagc cctgaaaagc tatggacata aatcaatggc tatcgtagaa aaaaacatac
    29221 aagcaatcga tcggacgacc gaactgcttc atcaagtcgc gatcccagac cattggagaa
    29281 cgttggagat gcctgaaaaa atcaataaaa ggaacactgg ttatatacaa gaaatacttg
    29341 aaccagtgaa tgcacaggaa ggaaatcaac tctctgttgg tacacttgta gcaaatggaa
    29401 tgacaactgg cgaaatgcct ttaggaacgg cttctatgga aaagcggggc gtcgctttag
    29461 aagtacctga gtggattagt gatcgctgta cgatgtgtaa tgaatgtgcc tttgtttgtc
    29521 ctcatgctgc catccgtcca tttttagcag atgaagagga aatggaagaa gcgccagaag
    29581 gatttatcgt gagagaaatg cgaggcgcag acggcgtaaa ataccgtatc caagtttcag
    29641 tggaagactg tacaggttgt ggtctgtgtg tagaggcttg tcccgcaaaa gaaaaagctt
    29701 tagtgatgaa gccttatgaa gaacagaaag aacaagctgt gaattgggct tttgcaatga
    29761 cattaagaca aaaagcaaat ccagtcaaag gaaagaatac tgtcttgtct acacaattca
    29821 atcaaccgct tcttgaattc tcgggcgctt gctcaggctg tggcgaaaca ccttatgtaa
    29881 aattattgac acaaatgttc ggtgatcgaa tgatgatcgc gaatgcgaca ggctgttctt
    29941 ctatttgggg cggtgcttct cctgcttctc cttatacgac caatgaatgt ggtcaagggc
    30001 ctgcatggtc aaattcttta ttggaagata atgctgaatt tggttatggt atgcttctag
    30061 cggcacagac tcgtcgcgag gctttggcaa gttcaatcaa agaagtattg ccaaaagtat
    30121 cagaagaact acgagaattg atggaagact ggttggtaca catgtttgag agcgaaggaa
    30181 cgcagcaaag agcagcaaaa ctgcaagctg cgatcgaaag cgaacgatca attgtccctg
    30241 aactggagga tatatacaag agaaaggatc tattcgtaaa aaacagccaa tggatgattg
    30301 gtggagacgg atgggcttac gacattggtt ttggcgggat cgatcatgta cttgccagcg
    30361 gagcagacgt gaatattctt gttttggata acgaagtcta ttccaatact ggcggtcaaa
    30421 cctcaaaagc aacaccagct tcggcaatcg ctaaattttc ggctagtgga aagtatgctt
    30481 caaagaaaga tctaggaatg atggcgatga catatggaaa tgtttatgtg gcgcaaattg
    30541 cttcaggtgc caatcaaatg cagacgataa aggcttttga agaagcagaa aagtatcctg
    30601 gaccttcttt aatcattgcc tatacgcctt gtatcacaca tggtttgctt ggtggaatga
    30661 aagaatcgct taaagaagca aaagaagctg tttcttctgg ctattggtca ttatatcgat
    30721 ataaccctgc aatggtcgaa aaaaacaaga acccaatgac tttggactac aaaaaacctg
    30781 atttctctgc tatgcctgat ttcatgagga aacaagttcg cttttcctcg ctagagaacg
    30841 caaatccaaa tcttgcaaaa gctttatttg aaaagactat ccaagacgct aaaacacgtt
    30901 tttacaacta tgctgcactg acgggagaat tagaaaaaat caagaaacga cttgaaccag
    30961 aggaatctat cgatgtaccc gttaagacta gaaaagaaaa aacgacggac cttgaagcag
    31021 aagaaagaag agctgccaga gcagaacgac gtaaaaaaat ggaacaagct acaaaagaaa
    31081 aaaaggaaaa ataacagaaa aaatataatg aataattctc tgaagtttaa aaatatttat
    31141 tgcagagaaa aataaaacgc atacttgcaa ttttcctgaa aattatgcgt ttttctcaag
    31201 aaaaatacga gcagatcagc ctctaaaatt aaaacatatg atatactaga gaggaaatct
    31261 caaaagagaa gagaggcttt ttatgtcatt tcaaatcggg gaacttttta atttggacta
    31321 ttggcagcaa atgttttccg gtgacttgtt ctctctgaat tttttggtga acatacttga
    31381 tattctggtt gtctggtatc ttgtatacaa actgatccaa ctgctgcgag gcacaaaagc
    31441 gattcagctt ctgaaaggtg tagctatttt tattgttatc cgaatcgtag cggaaatcat
    31501 tggtctgcac accttgtctt ggctgatgaa ccaagtcatt acgtacgggg tgatagctgc
    31561 tatcgtgatt tttcagccgg aaatccggag aggactggaa catcttggac gcagttcgct
    31621 tttcaaacaa tcaaaaagcg aacagcagga agatgagaag atgatcttgt cttttgacaa
    31681 agccatccaa tatatgtcca agcgaaaaat cggtgcgcta attactatcg aacggcatac
    31741 tggattagat gagtatattg agacaggaat tgcattagat gcagatatca ctggagagct
    31801 gctgatcaat atctttattc ctaatacacc gctgcatgac ggtgcagtta ttgtaaaaga
    31861 aggaaagatc gcagtagcaa gcgcctatct tcctctatca gaaagtatgt tgattccaaa
    31921 agaattcggg actcgacacc gggcagctgt cggtataagc gaagtcagcg acgcgattac
    31981 catcgttgtc tctgaagaaa ctggggatgt cagcattaca ttagataatg aactgatggc
    32041 tggcttatcc cagcaagaat atttggcaat tttgcgtaga gaactgattg ctgaagagaa
    32101 aacaaaaaac aagaaaaacg tgattcaatc tttcctagac ggtatgacta agggagggga
    32161 tcgcaaatga tctcaaaaga gaaacggaca agcattcttt acagttttat tgcattgctg
    32221 ttcagtattg cgctgtactt caatgcaaat ggccagtccg ttccaaatac gctttctgga
    32281 aatgaagcgt ataatcaaac agttactggg gtgccaatca agatttctta tgattcaaag
    32341 cgctactata tccatggata tgaaaatgca gtgactgtca aactttccag tgcaaaccga
    32401 gttcagttga atgcagaggc aaacgaagat acacggatgt tccgcgtcac agcagatatc
    32461 actaagctgg gcgaaggaac acatgaggtt ccgctaaaaa ttcaaaattt gagcagtgct
    32521 gtcacagcaa agatcgaacc atcgactatt acagtaacgg ttgagaaaaa ggtaataaaa
    32581 gatttcgatg tggaaacgtt gattccttca acgttcacac catctggata tgaacttgat
    32641 gatacttccg ttagtcctaa aaaagtctct atcactacag gtgacaaaac attggcagaa
    32701 atcaaacgag tagtagctga tgtggacgct tcgatggtca cagatgatgg gattaatagt
    32761 gaggtcccaa tacaggcgct gaatgcagca ggggaagtat taagtatcgt ctctgatcca
    32821 gtgcaagtaa cagtgagagc tgattcgatc aagccaagca agtcggtacg actttatggg
    32881 atacagcaag gaacaccagc tgccggggta gaaagctatg atttcagttt ttcaaaactg
    32941 gaagcagaag taagcggctc tagcgatttg cttgcatcga tcggtgacag tattgctgta
    33001 ccgatcaatg tctcaggtat caatcatcga acaactcgta aaattgaaat accagtagaa
    33061 gaggggttaa gtatcaagcc cgaatcagtt agtgtggaga ttacacccgt gttgcaaacg
    33121 tcaagcagta gctctgcttc gacgagcagt cggacacaag aaaatacaag tacgagtaga
    33181 agtatttcat ctgctgattc aggaacggaa ccatcgacaa caaccatttc ttccagttcg
    33241 gaatctggga caagcagctc gaccacaagt acagaagaaa catcagaaac aagcgaatca
    33301 acacaaatga gcagaacaaa ttcctcagaa aattaagtta aaggagtaat tttacaacta
    33361 tgggtaaata ttttggaaca gacggcgtac gcggtgaagc caacaaggaa cttacgccag
    33421 aacttgcatt taagctggga cggtgcggag gttatgtcct aagccagcat gaagaagaag
    33481 gaaaacgccc acgcgtgtta gtagggcggg atacaagaat ctcaggtcaa atgttagaag
    33541 aagcgctgat ttcaggactt ttatcggtgg gtatcgaagt gttccagcta ggtgtgatct
    33601 ctacaccagg tgttgcttat ctgacacgtt tgcaaaaagc aagcgcaggg gtcatgattt
    33661 ctgcttctca taatccagca caagataatg gaatcaaatt tttcggtgca gatggtttta
    33721 aactagtaga tgaccaagag ctagaaattg aagcattatt agatgctgaa gtggatgaat
    33781 tgcctcgtcc atcagctgaa ggattgggaa ctgtagaaga atttccagaa ggcttattga
    33841 aatattctca attccttgta caaacgatca acggtgacct ttccggtttg accatttgtg
    33901 tcgatgcagc aaacggagca acttcaacaa gtgttaatcg tttgtttgcc gatcttgaaa
    33961 cagattttta taccatgggc acaaatccag acgggttaaa tatcaatgat ggcgtaggct
    34021 ctacccatcc agaacgttta gctgagatgg tcgttgaaaa aggagcagat gctggactag
    34081 ctttcgatgg cgatggcgat cgtattattg cggtggatga acttggaaac attgtcgacg
    34141 gtgataaaat catgtttatc tgtgctaaat acttggcaga aaaaaatcga ttgaaaaaag
    34201 atacgatcgt tacgactgtc atgagtaact taggattcca caaagcggtg gaaggaatcg
    34261 gtttgaaaga tgtcgttaca caagttggtg atcgttacgt tgtagaagaa atgcgcaaaa
    34321 acgattataa ctttggcggc gagcagtctg ggcacatgat tttcttagat tttaacacaa
    34381 ctggagatgg gatgctttca ggaattcagt tactgaatat catgaaacag acaggtaaga
    34441 aattatcaga gcttgcagca gaggtaacaa tctatccgca aaaattagtg aatatccgag
    34501 taagtgataa aaacggtgcg atggatgttc cggcaatcaa aaaagtgatt gaagaggcag
    34561 aagctgaaat gggatcagaa ggaagaatcc tagttcgtcc ttccggtaca gaaccattac
    34621 ttcgagtgat ggcagaagcg cctactgatg agaaagttaa ttactatgtc gataaaatcg
    34681 cggcagtagt caaagaagaa atcggactgg attaagagat attttcataa aaaataaaag
    34741 aacaaggacc agtgtcagat gtctgacact ggtccttgtt cttttattat tctactgtca
    34801 ctgatttcgc taaattacgt ggtttgtcaa cgtcgaatcc ccgtaatagc gttgcgtaat
    34861 atgcaagtaa ttgagtcggt acgactgtgg ttagagtagt tagataaggg tggacagttg
    34921 gtagcaccag ctggtcactt tccttttcta atccctctga gacaataact agtgttttag
    34981 cgccacggct ttcgacttct ttcaggtttc ctcgagtatg cgcaccagtc acttcttcac
    35041 tgatgattcc aatcactggt gttccttctt cgatcaaagc aatcgttcca tgtttcaatt
    35101 cgccagcggc aaaaccttct gcctggatat aactgatttc tttcaatttc aaagcagctt
    35161 caagagaaac gttgtagtca gcgccacgtc caatgtaaaa ggcatttctt gtatcgctga
    35221 gatatacttc tgccaactct tctaaataat ctttttgggc gatgaccgat tccatcgcat
    35281 tagcaactaa actcaattca tgagtgatat cgaatacaag agaagtttca aattcttttt
    35341 tatcaccgat agctttggct aataaagtta gtacagctat ttgtgcagta taagctttcg
    35401 ttgatgctac tgcgatttcg ggtccagcat gcaatagcag tgtaaaggat gcttcccgcg
    35461 aaagagtaga accagcaaca tttgtaatcg taagtgaagg gtagccgaga cggttgattt
    35521 ttaccagaac ttggcggcta tctgctgttt cgccactttg actcaagaaa ataaagaatg
    35581 gtttttttga aagaagaggt gtgttatagc caaattcact ggctaaatga acctcaacag
    35641 ggatctgtgt caatttttcc agagtctgtt tacctgctaa ccccgcatgg taactagttc
    35701 cgcaagcaac gatatagatt cgatcgctat cagacaatgt atcgaccagc ttttgatcaa
    35761 gagagacacg attgtcttct gttacgtatt tttgagcgat acgacgcatg ataataggct
    35821 gttcgtcgat ttctttcagc atataaaaag gataggtacc tttctcgata tctgaagaat
    35881 ctacttgtgc ttcgaatgaa gaacgttcta cgatgtcacc tgcaaaattt tgaataataa
    35941 ctttttctga tgtgacggta accatctctt catcttcaat ctcaacgaat tccttcgtat
    36001 gagcaagcat agccattgca tcgctggcaa tcacattgaa tccatcgccg agtccgatta
    36061 atagtggact tttattttta gcgacgtaaa taacatcagg tgctgtccga tcaatcaaag
    36121 cgaaagcgta agaacctttg atgacccgca aagcttttaa aaacgcctct tgcgttgtag
    36181 tatccttcgc gaaagtttca attagatgag cgataatctc agtatcggtc tcaccaataa
    36241 agtggtcatt tgctaaataa gcaattttaa gttcttcaaa gttttcgatt acgccattgt
    36301 gaacgagcac gaagcgtcca ctttgggaag tatgtggatg ggcgttttct tcagaaggtt
    36361 gcccgtgagt tgcccagcgt gtatgaccaa tacctatatt tcctgtagta tcaatattta
    36421 ttttgttttt caaattttga attctgcctt gtgctttgac cagataatca gttgtgccat
    36481 ctgagacaaa gataccagct gaatcataac cacggtattc taatttttct agaccgtcaa
    36541 tcaatcctgg tgttacattt tttaatccaa tcattccaac aattccgcac ataaaaaaca
    36601 tcctactttc tataatgaat tcgtatgaat gcttccagct gcaggaaaat ccttttgttt
    36661 tatctttgca gatatttttt gtggattttc tgtagagtgc agtccctagg gccatccgcc
    36721 gaatctttcg ataaaccctc tcctcgtcat ctgtttacac agacctggcg ctatcctaaa
    36781 aggtataact atcctcctct tttgtttttt atctggaaac atttaaaatc ataacctttt
    36841 gcgaatgttc ttgtcaacaa aaaaagaata aaaaataaat tggtatatat caaatgcttt
    36901 gtcaaatgct ctttttatgt caaaaaataa tgggttttta tctatcatct ttttcaggag
    36961 ttcggtacaa tagaaagtaa tcggatagag gaggagtaaa aatggattca aaaattgaga
    37021 tcatgacact gggaatgtta aaaaaacaat tgtccaaatt cgaagcatca gctggtgtat
    37081 cagatgatac gaaaatattt ttagatactg gctgggatag catccaagaa atcgcacctg
    37141 atgccttgga agttgctgaa gctcgtgagt ttacggtaga agatgaattg acaaaagagt
    37201 cgttttccgg gtatgcgcgg gaagaaaaag cagagcggtt cgacacttct gagcagtcag
    37261 aaactgtgat cgtcataaaa aacttgtatt agaaaggaga aagaatgaat aagagacgtt
    37321 gggcagcagt tctgattgct gcaggattat ttgtggtttc gttagtttca gctagtttga
    37381 ctaagcctca ggaaaacgat caaattgagg gattgaacag ttggttatat ggggatgaag
    37441 aactagcttc aaatgtgttg gaagagggag acagtacgca aaaaatcgta aaattatcag
    37501 tagatggaac gattgctgcg ggagggtctt caggtttatt tgcttctgaa ggttacaatc
    37561 ataaaaattt tatggaacaa ctgaaggcga ttgaagaaga tccaacagtc aaaggtatct
    37621 ttttagaagt aaattctcct ggtggcggtg tctacgaaag tgcggaaatc gctaagaaat
    37681 tggatacgat tcgtaaagaa catgatatcc caatgtatgt cagcatgaaa aacatggcag
    37741 ctagcggtgg ctactatatt tctgctcaag cagataaaat ctttgcaaca gaagaaacag
    37801 tgaccggctc aattggtgtg atcatgtcag gattgaatta ttcaggactt ctagaaaaac
    37861 tgggtgtgga agatacaaca gttaaaagcg gagcgttgaa agatatgggt tcaggaacgc
    37921 gaccagagac aaaagaagaa gaagcggtgc ttcaagcata tatcgacagc gcatatagtc
    37981 gttttgtagc aatcgtcagc gagggacgga ataaatctga agaagaagtc aaaaaaattg
    38041 ctgatggaag gatttatgat ggtgtccaag caaaagaagt aggtttagtc gatgaattgg
    38101 gatttcctga agatgcttta aaagctatgc gaaaggaaca acagcttgaa gatgcggaac
    38161 tagtagaata ttcttccacg ccatctgggt ttgctagtac atggttagga agtaaactag
    38221 cagaattcca gggattgaag ccttctgaga ctagtcagat cttatccgtt cttgagaatc
    38281 tagggacagc ggaatcacca aaagcaatgt attattacgg aggtgagtaa gcatgtcaga
    38341 gctttcaaat gaaaataagg aacaagaaaa agataagcaa cagcagcctg ctgtaggacc
    38401 tgactccaac ttttcccaaa aggtactgag ctcttttgaa agagagcctt tgacgcccga
    38461 agaaatcaaa aagaaacaac gtaaatggaa aaagtatacg gacacaagaa atgaaccgcc
    38521 aaaagcaaat gattttccta agtatttcta tgcaggtttt tttatccgaa tgtttgcttt
    38581 cttggtcgat cttttgtgta tcggagctat tacgcgttta acacttggta ttgccaaaaa
    38641 tctaggttgg cttaattttt cagattctta tctgagtatc tacggattca cagccttact
    38701 tatttatcta gcgtatttta ttttattgac gaaattcaat catggtcaaa cgattgggaa
    38761 aatgatcttt ggtattcgag tcatcagctt tgatgaagaa gaacttagct ggtcaaccgt
    38821 tttagttaga gaaggtgctt gccggttcat tctaaaattt cctttgctga tgttagggta
    38881 tcttccagca atctttaatc agaaaaagca acatctaggc gattttttca ctaatacaag
    38941 tgttgttacg atcaatctga tcaaagcatt caaccaggaa gtcaacagct gatgagcaat
    39001 aaaaagcagt aacagttgaa agcaccttct aaaagtcaga tctaaaatct agcttttaga
    39061 gggtgcttca gttattttta attgtcatgc tttttttgtt ttgctactat tgaacatgag
    39121 ctgaacatga gcaagaggag gacactgcgt gaagccgatt gattttccag aaaaatatga
    39181 gaatttaatg cgagtagcac aacaagcact agcaaaccag caatatcagc aggcaaaaga
    39241 attatttcaa cgagcttacg agttgaaaga aagctttgag gctaatagcc tgcttgtttt
    39301 ttgtctttac gagttggacg agaaaaaaga agcattgaag caagcactct tgcatgaaaa
    39361 acagtatctt caaaatgagg agtttgctga attttatttt gacttgttaa tcagtacaca
    39421 agatttttta tatgctagaa aattgatagc aagtacagat ttttatgaag ctttcgagca
    39481 gcgggtcatt gaaaaaatcc aatttgcaga agaattatcc ggacaaatgg agaggcagaa
    39541 gatcaaggca ctccacaata aatcggagga acttccttcg ttggaacctg cacgtcagct
    39601 tgcgtctatt gatgagatcg aacagcttcc ttatcatgag tttatccaaa cagcgagtaa
    39661 acttattgta tcgccagagg tccatatttt agcaagggca aaattactgg agacacttag
    39721 gcaattgaac gaatgccatc ctgttttcta tttgacgatt gaagaaaagt tagtcaaagt
    39781 cataccaaaa gatctgccaa agccgcagca gcaggcaagt taccagcaat tatgtgtatt
    39841 ttcagatcgt tacggtaatg aagatgcgct gcttagttcc gtgttaaatg aagaattcac
    39901 gttgcaatct gcaattgttt atcctgtcta tgatacatac atcgaagacc cgaagcgctg
    39961 gtttcaactg actgtagagg cgtgtacagg aaaaacgatg tatgaaggta cagaagatga
    40021 aaaacaagat tttttaaaaa aaagagaaaa aattttgcag caaatgatct tcttccatta
    40081 gattttatca gtgaaaaaga taaaaatgtt atgaaaaaca aggattctat ccattcaata
    40141 tgtttacaat ttgaaagggt tagtgtacta tttaaaggta tgcatgaaac gtttttgatg
    40201 tataaaatga atttctaaac tcggagggaa ttaaatgact gcaacatttg aaaaaaaagg
    40261 cacgaatgat ggtgttttaa aatttacgat tgcgcaagac gaaatccaaa aaggattaac
    40321 aactgcgttt aataaagtga aaaaaagctt gaacgtacct ggattccgta aagggaaagt
    40381 ttctcgtcaa gtattcaacc gtatgtacgg tgaagaagct ttatatgaag atgcattgaa
    40441 tgctgtatta ccagaagctt atgaagctgc tgtcaaagaa gctggcatcg atcctgtttc
    40501 tcaaccaaaa atcgatgttg aaagcatgga aaaaggtcaa gactgggtaa tcactgctga
    40561 agtaacagtg aaaccagaag taaaattagg acaatataaa gatctagttg ttgaaaaaca
    40621 agaccgtgaa gtaacagatg ctgacgtgga tgcacgtatc aaacgtgaac aagaagcaca
    40681 agctgaatta gttatcaaag aagatgctgc agctgaaaat ggcgatacag tagtaatcga
    40741 cttcgaaggc tttgtagatg gcgaagcgtt tgatggcgga aaaggcgaaa attactcact
    40801 tgaattaggt tcaggctcat tcattccagg ttttgaagat caattagttg gtcataaatc
    40861 aggtgaaagt ctagatgtaa atgtaacttt cccagaagat tatcaagcag aagatcttgc
    40921 tggaaaagaa gcagtcttca aagtgacaat ccatgaagta aaagcaaaag aagtgcctga
    40981 attagatgac gaattcgcaa aagatgttga tgacgaagta tcaacattag acgaattgaa
    41041 agaaaaatat cgcaaagaat tagtagaaac aaaagaaaaa gcagcggacg atgcaaaaga
    41101 tgaagcagcg atccgtatgg ctgttgaaaa cgcagaaatc gttgaattgc cacacgtgat
    41161 ggttcatgat gaagtacatc gttcaatgga cgaattcttg aacaacatgc aacgtcaagg
    41221 tatctctcct gaaatgtact atcaattaac tggttctaca gaagaagact tgcataaaca
    41281 attcgaaggt gaagcagaaa tgcgcacaag aacaaatctt gtgatcgaag caattgcagc
    41341 tgctgaaaat cttcaagcaa cagaagaaga aatcaatgca gaaatccaag aattatcaga
    41401 aacatacaac atgccaatcg aacaaatcaa acgcgtgttg acagaagata tgctggaaca
    41461 tgatgtgaca atgaaaaaag caatcgaatt gatcacaggt acagcgacag aagcgaaaga
    41521 atagaaatca agtaataaat catttctgaa gaagctactt ctagaaaatt gtttattcga
    41581 aataagggac tgtgacacga ttttgtcaca gttccttatt ttttgttaag agtaaaaaat
    41641 gcaaaggtat aggtcagttg atcctttgtt aaacactttt tctttttact aaactatgtt
    41701 atgatagtaa aagactgtaa agtctttgat agtttcttgc atactttttg caagttaagg
    41761 ggtgaagacc atgtatgaca atccaagtag caatgagacc gtacgctgtt ctttttgcgg
    41821 gaaaacccaa gaagaagtga aaaagatcgt agctggtcca ggggtctaca tctgtaatga
    41881 atgtatcgac ctatgtaaag aaatcattga tgaagaattt tatgaagaag ctgtacgcga
    41941 attcactgaa gtccctaaac cactagaaat tcttgaagta ttgaataact acgtgattgg
    42001 acaagatcgc gcaaaacgct cgttagctgt tgccgtatac aatcactata aacgtgtcaa
    42061 tcagcaagca caagaaaaca cagatgatgt tgaactgcaa aaaagcaata tctgcttgat
    42121 cggacctaca gggtctggta aaacattttt agcacaaaca ttagcaaaaa cattgaatgt
    42181 accttttgca atcgcagatg cgacaagttt gacagaagct ggttatgtgg gggaagatgt
    42241 agaaaacatt ttgcttaaat tgcttcaatc tgctgattac aatgtggaac gtgcagaaaa
    42301 agggatcatc tatattgatg agatcgataa aattgcgcgt aaaagcgaaa atgtatctat
    42361 tactcgtgac gtttccggcg aaggtgtcca acaagccttg ctgaaaattc tagaaggaac
    42421 tgttgcaagc gtgccacctc agggaggacg taaacatcca catcaagaat ttattcagat
    42481 tgatacgacg aacatattgt tcatcgtagg tggtgcattt gatggcatcg aaacgattgt
    42541 gaagaatcgt atgggcgaaa agacgattgg atttggtaca caaaaccaaa aactttctga
    42601 agacgaaagt gtcatgcagc atatcattcc tgaagattta ctaaaattcg gattgatccc
    42661 tgagtttatc ggacgattac ctgttatggc agctttagag aaattgacaa cagatgatct
    42721 ggtacggatc ttgactgagc cgaaaaatgc gctagtcaaa caatatcaaa aacttctttc
    42781 tctagataat accgaacttg aattcgaacc tgaagcgttg agagccattg cgaaaaaagc
    42841 aatcgaacgc aataccggtg ctcgaggact tcgttccatc attgaagaaa tcatgatgga
    42901 tgtgatgttt gatatccctt caaatgaaaa catcgaaaaa gtgattatca caaaagaagc
    42961 agctgaattg tctggtgagc caacagtaat ctataaagat tcagagaaaa aagcgggttg
    43021 atgaaaagag gctgccgtaa aagtcatttt ggcttttgcg acagccgctt gctttattca
    43081 tcaccttgtt aaggagagag accatgaaag tccatcaagc tgaaattatc ataagtgcag
    43141 tggcaccaaa acaatatcca gatacacaat tgccagaaat agctctggca ggacgatcaa
    43201 atgtagggaa atcttctttt atcaacacat tgattgatcg aaagaattta gcccgtactt
    43261 ccggtaagcc aggaaagacc cagacattga atttttattt gatcgagaac gcattacatt
    43321 ttgtcgatgt tccgggatat gggtatgcaa aagtatccaa aactgagcga gcaaaatggg
    43381 gaaagatgat cgagacatat ttaacgacta gagaccagct acgtgcggtc gtttctttag
    43441 tagatttgcg tcataagcct tctcaagaag atatccagat gtatcaattt ttgaagtatt
    43501 atgatatccc tgtaattgtt gttgccacta aggcagataa gatccctcgt ggtaaatgga
    43561 acaagcatga gagcgaaatc aaaaaagcgt tggattttga tcgcaatgac acgtttattc
    43621 tcttttcttc cgttacaaaa cagggaaaag aagaagcgtg ggcagcaatc gaacaagcaa
    43681 ttgaatcata aaaagaataa aaaagactta ccagtcaaac tctttcataa aagtttggct
    43741 ggtaagtctt tttttgagct taacttactt ttgtttcttg tcttttttct tttcattttg
    43801 tggctgtggt tttagaaatc gatcgatctc ttcttttggt gcaactgttt tttccggatc
    43861 gacagcaaat gattcgaaaa gtttatctaa attatctgta cgttcaaatt tcaaccccat
    43921 tgtaaacacc tctttgtttc tttttactta gtctatcatg taatcgtcca aattggtttc
    43981 taagacataa agttttagtt t
//
LOCUS       DACDAF010000014        43935 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.014, whole genome shotgun sequence.
ACCESSION   DACDAF010000014 DACDAF010000000
VERSION     DACDAF010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 43935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.014"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(144..494)
                     /locus_tag="IVZ69_000704"
     CDS             complement(144..494)
                     /locus_tag="IVZ69_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182813.1"
                     /translation="MIFENESEEIGRMTEENKVDLLETLVINKKEFEQLFLDFFVQYD
                     RIYDFNSSLDLFELEAEIIENSREKNGKIIISVEKFNELFSETFEIDADYYQPQEVFR
                     EFRNKIIGFSQTTK"
     gene            complement(535..1029)
                     /locus_tag="IVZ69_000705"
     CDS             complement(535..1029)
                     /locus_tag="IVZ69_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182814.1"
                     /translation="MFKVYFPFQWLVKGIFFVLLGLILFGSYLTIKARYFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIELTEKRNEFAQHDRVLQVTYTMKNDTENPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESGKSETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFNL"
     gene            complement(1022..1324)
                     /locus_tag="IVZ69_000706"
     CDS             complement(1022..1324)
                     /locus_tag="IVZ69_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182815.1"
                     /translation="MSDPYIKVYCSKETKKLFDSFYEKNKGTLGTKANMFRVMVSNLP
                     MLASQSNKKFSDPESIKLEQTISELESSIMKKLDGIDQKLSCSLKTKYKTEEKKDV"
     gene            complement(1347..2684)
                     /locus_tag="IVZ69_000707"
     CDS             complement(1347..2684)
                     /locus_tag="IVZ69_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP8182816.1"
                     /translation="MGSIIKIASKSRSIHNTISYMLNKQEDSELVTGIGVSNDLNAIE
                     EFKRTNEIFGDKGKIKLWHFTQSFDPLEDISAEKAHELGVKWAEKMFPNQSILVVTHT
                     DKGHVHNHFGISPNDQRTGKKMDIRKNDIRVLQAWNDNILIDNGINPLDMYKYNHLVA
                     DRENWKEREFRTENKISNREKIKLAVSEVAQYAKNYDDFHAELKKNHSIETYRFAKNQ
                     RIGYKLLDSEDGLILKIGGKRLGQNYDMNYLDDLFTENKKAEQIQSEEVLTEIAIRYL
                     GKSLNGRADSRFNWQERAQRFELDNENIPFLRSSKDYEEFYDKYKFEIEDRIENLLDV
                     FGENKNQFFGFAVEEEPLKYKKKCVNLVYKKVVYDIAESLSTDYDQFNIQDTEPALKR
                     NFKKRYIQETKRVLYLFNRAIDDGTIEKARREYEETARGIDYQKQQNQYDMDF"
     gene            complement(2669..3166)
                     /locus_tag="IVZ69_000708"
     CDS             complement(2669..3166)
                     /locus_tag="IVZ69_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182817.1"
                     /translation="MAIDVSKLPLEERRKRYKRNEDSRRQNRPIKFRVDDYQYQELEK
                     TADIFGLSVPMYVKKIAVDNAGKSLKYTDRQYKEINFHLLAIGRNLNQLVKTANYLRV
                     QLNKKDTEIQKEEHQSVYLSFTTKQERLKRLYAEKNDLMIQIKSISDPLNRLEKELNK
                     LWARL"
     gene            complement(3315..3653)
                     /locus_tag="IVZ69_000709"
     CDS             complement(3315..3653)
                     /locus_tag="IVZ69_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182818.1"
                     /translation="MARKKQKSIADLKKELAELERKLYPELGKYVYEKTGISSVKEFE
                     ETFEINQKGTQEKWQKAVNFANSEFTLVHEFLASDQLMETKFQQFLRRKGETAYRIFY
                     REEAQEESVR"
     gene            complement(3657..3842)
                     /locus_tag="IVZ69_000710"
     CDS             complement(3657..3842)
                     /locus_tag="IVZ69_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182819.1"
                     /translation="MQLILQISTQDFLELAELCDSVKKATNEKITVTNYIELMIQEEL
                     VMKNELMNELSHIQKGA"
     gene            complement(3856..6609)
                     /locus_tag="IVZ69_000711"
     CDS             complement(3856..6609)
                     /locus_tag="IVZ69_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182820.1"
                     /translation="MKIIKKKIDNRKINWLLISFLILIAMIIFTSNVAEGSIFNWFDD
                     TESQTEFLTNPLYQNYLKKYNGNFYSQFGMWIGWSVIKSMFAIVDGIQNMIPEVLDLF
                     SFVESTGLNKVYQSVLSTIVVGLMILSLVIIGYKMITGKGTVDLKSVGMNVVMSVALI
                     LLMPTLIHSGIEFSKTFYNDTTTITNSDEGVAWSLIEQGVTDLAYINKTDQYSMINKT
                     NDRNNLTKENFWKTDLTQVLTDNVIDKMEKENPTADNLRYELVENSDNEFVATKFSDN
                     FLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRVLGVLV
                     FATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFVNYLNAGEGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRSKGGKN
                     SGGNDQAEGEERKPERNFGQSLSQKANKTGKTLGYARERRLSGLASDGATMASERATK
                     PFKSMRDMANDTKNKFKEGLDDGTMSAINKNSKPIVAKNKEDETGKYADSMPTRLSDR
                     KDGAKVENADRIMSSSERMREAMKNNAESNINPASAIQQKVKQDIEERKNAMHGQAKS
                     AEELINQKRQEAKYTPEAMNREEMLRKRVEGRTGANMDEKEALTKERIQEAKNSNTGL
                     EKSVKENPQNSTSSQDRRSVDVRENLQNTTSSQNGNRTVDVRENVQSSGTSQPRTVDV
                     RENLQNTTSSQNGNRTVDVRENVQSSGTSQPRTVDIRENLQNTTSSQNGNRTVDVREN
                     VQSSASNQPRTIDVRENLQNTTSSQSGNRTVDVRENVQGSASNQPRTVEVRETRAEAS
                     QGDKTQKINIVEERKERPNEKVIVEQEVKEKKRQRFTYENNPLFQDISDKPNPLFDSL
                     FKK"
     gene            complement(6596..6814)
                     /locus_tag="IVZ69_000712"
     CDS             complement(6596..6814)
                     /locus_tag="IVZ69_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182821.1"
                     /translation="MIENHLVDKIYCLDHNADTLELIESICSNTIVLDLRAVNDDYVT
                     HIIVNKKMAQKLSESLKKWAEGGNNENN"
     gene            complement(6807..7547)
                     /locus_tag="IVZ69_000713"
     CDS             complement(6807..7547)
                     /locus_tag="IVZ69_000713"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182822.1"
                     /translation="MREKLKKLGDKKRHTFQGTFEFNGYKKDKYKFGQEYENATFMLS
                     NLKIVQGDNLELVTDHIWMNLTKQFLKFGWLKKGDMVQFDGRIKSYSSKKGINYKIER
                     PSKVKVFRKGTEINESSALKISTRYEIVEDIKRQNREYYEARDFFFENYFSVPRYFKL
                     KEKWPEIQAVVAINENRYTSEQFKQVFKDRDSLVDLYKKIQETDKYNLQKEFYNGLVS
                     NKNRIDLNEVEGYLHKIENFDYGRGYFD"
     gene            complement(7680..8564)
                     /locus_tag="IVZ69_000714"
     CDS             complement(7680..8564)
                     /locus_tag="IVZ69_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaD"
                     /protein_id="HAP8182823.1"
                     /translation="MIFMAEKRMLAKSFLNNASFMKMSDSAKLLYVYLNTNADDDGIV
                     EAYPYTKMLGTPDDDVKILFTKGFVFFLNEDLLAFLPHWLQNQNIRIDRYKPSIYRFK
                     LLNLKPEFFSKLKPIKFDMILQSGQVEPLRVDLMEKWYPAGIPCDVKSDTQLSQDQNS
                     QDQTNQDKDSIEEINQDQNSFFENIINQKGIQIITRLGDRYTEVQREKYLKLIASMKD
                     SIEREYKIEIRGQDYFDITNKMLTRLFNSINEKLNLGEEIDEMKFINTTARNHWEDIA
                     KQEKASRLDMLETLKKIG"
     gene            complement(8725..9052)
                     /locus_tag="IVZ69_000715"
                     /pseudo
     CDS             complement(8725..9052)
                     /locus_tag="IVZ69_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9061..9258)
                     /locus_tag="IVZ69_000716"
     CDS             complement(9061..9258)
                     /locus_tag="IVZ69_000716"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8182824.1"
                     /translation="MFQINEDFSIRIRERRGKLMITKTKAAELIGISRQTLKKIECFE
                     VQSVSKNVYQKIIGWLLKSDY"
     gene            9425..9799
                     /locus_tag="IVZ69_000717"
     CDS             9425..9799
                     /locus_tag="IVZ69_000717"
                     /inference="COORDINATES: protein motif:HMM:NF013540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8182825.1"
                     /translation="MTQKNRIKETREEQNLTLKELSNLSDIPYQTLRNYEIGKRKPRN
                     DEVWWKLGTILNVRGPYLKGEDSFKTNDELHIYYLKKSHTNFELSKKEEIIDIIDKLN
                     EDGLDEALRQLALLSKIDDFKR"
     gene            9889..11055
                     /locus_tag="IVZ69_000718"
     CDS             9889..11055
                     /locus_tag="IVZ69_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8182826.1"
                     /translation="MSIQKYKTKSGTRYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDMGYHRPSNDLFRTVYEEWLPSYKNRVQETTYQRTKDLFRLHILPKFG
                     DKSISKITPIYCQNAINEWAVKYTNIKQLKSYSSQIFEYAIFAELLQRNPMTNTKLPK
                     QEKKESENYFSLEELKEFLEILNKEESLKHILIFQLLITTGVRKGELSALRWADINFE
                     EQLLHIGKSYATIRTEDPNATRKTIRIQKNTKNVSSERILPIDTQTIEMLKLWKKEQA
                     EVLLQFGINANTKKQLIFTYVNANGDVNQPLHADYSNNIMRRLEKKYKFKHVTIHGLR
                     HTHATLLLEGGASIKEAQDRLGHKNAETTLNTYSHVTEKAQRNAVDKFIAYTGL"
     gene            complement(11154..11546)
                     /gene="rpsI"
                     /locus_tag="IVZ69_000719"
     CDS             complement(11154..11546)
                     /gene="rpsI"
                     /locus_tag="IVZ69_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP8182827.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(11562..12005)
                     /gene="rplM"
                     /locus_tag="IVZ69_000720"
     CDS             complement(11562..12005)
                     /gene="rplM"
                     /locus_tag="IVZ69_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HAP8182828.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(12524..12991)
                     /locus_tag="IVZ69_000721"
     CDS             complement(12524..12991)
                     /locus_tag="IVZ69_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HAP8182829.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(13111..14649)
                     /locus_tag="IVZ69_000722"
     CDS             complement(13111..14649)
                     /locus_tag="IVZ69_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HAP8182830.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            14729..15415
                     /locus_tag="IVZ69_000723"
     CDS             14729..15415
                     /locus_tag="IVZ69_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HAP8182831.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(15616..16143)
                     /gene="msrA"
                     /locus_tag="IVZ69_000724"
     CDS             complement(15616..16143)
                     /gene="msrA"
                     /locus_tag="IVZ69_000724"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP8182832.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(16227..16904)
                     /gene="pgmB"
                     /locus_tag="IVZ69_000725"
     CDS             complement(16227..16904)
                     /gene="pgmB"
                     /locus_tag="IVZ69_000725"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HAP8182833.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(16901..18031)
                     /locus_tag="IVZ69_000726"
     CDS             complement(16901..18031)
                     /locus_tag="IVZ69_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP8182834.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(18031..20214)
                     /locus_tag="IVZ69_000727"
     CDS             complement(18031..20214)
                     /locus_tag="IVZ69_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HAP8182835.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(20211..21236)
                     /locus_tag="IVZ69_000728"
     CDS             complement(20211..21236)
                     /locus_tag="IVZ69_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP8182836.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(21281..22108)
                     /locus_tag="IVZ69_000729"
     CDS             complement(21281..22108)
                     /locus_tag="IVZ69_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP8182837.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(22105..23172)
                     /locus_tag="IVZ69_000730"
     CDS             complement(22105..23172)
                     /locus_tag="IVZ69_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HAP8182838.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKHGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLIGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(23198..24034)
                     /locus_tag="IVZ69_000731"
     CDS             complement(23198..24034)
                     /locus_tag="IVZ69_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8182839.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(24031..24900)
                     /locus_tag="IVZ69_000732"
     CDS             complement(24031..24900)
                     /locus_tag="IVZ69_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8182840.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(24970..26253)
                     /locus_tag="IVZ69_000733"
     CDS             complement(24970..26253)
                     /locus_tag="IVZ69_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP8182841.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(26267..27952)
                     /locus_tag="IVZ69_000734"
     CDS             complement(26267..27952)
                     /locus_tag="IVZ69_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HAP8182842.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            28227..29252
                     /locus_tag="IVZ69_000735"
     CDS             28227..29252
                     /locus_tag="IVZ69_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8182843.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(29847..33500)
                     /gene="rpoC"
                     /locus_tag="IVZ69_000736"
     CDS             complement(29847..33500)
                     /gene="rpoC"
                     /locus_tag="IVZ69_000736"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HAP8182844.1"
                     /translation="MIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYRTLKPERE
                     GLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHIELAAPVS
                     HIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTEREYREKRE
                     QYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLDILEAFRA
                     SGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLKRLLDLNA
                     PGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGK
                     RVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKNAKRKIER
                     QEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVCEAYNADF
                     DGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTMEEEG
                     REGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMITTVGKII
                     FNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKKKNLGNII
                     AEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIENAHKQVET
                     ITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSGARGNISN
                     FTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTRKEVRHPE
                     TNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNLATGSDVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNPKGQAVIT
                     EVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGAPLTEGSI
                     DPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRVMDPGDTD
                     ILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAASFQETTRV
                     LTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVYSISDIEA
                     QMAAEDAMNNQTK"
     gene            complement(33579..37196)
                     /gene="rpoB"
                     /locus_tag="IVZ69_000737"
     CDS             complement(33579..37196)
                     /gene="rpoB"
                     /locus_tag="IVZ69_000737"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP8182845.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            37924..38892
                     /locus_tag="IVZ69_000738"
     CDS             37924..38892
                     /locus_tag="IVZ69_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP8182846.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            38910..39815
                     /locus_tag="IVZ69_000739"
     CDS             38910..39815
                     /locus_tag="IVZ69_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182847.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            39812..40618
                     /locus_tag="IVZ69_000740"
     CDS             39812..40618
                     /locus_tag="IVZ69_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8182848.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            40775..41743
                     /locus_tag="IVZ69_000741"
     CDS             40775..41743
                     /locus_tag="IVZ69_000741"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HAP8182849.1"
                     /translation="MTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKAIKELEKA
                     GYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAKLAAAQGD
                     SVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTIIAASACVK
                     AIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLNFSVPQNH
                     FPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKSFVLGKTV
                     SFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(42060..42584)
                     /locus_tag="IVZ69_000742"
     CDS             complement(42060..42584)
                     /locus_tag="IVZ69_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinB family protein"
                     /protein_id="HAP8182850.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            42871..>43935
                     /gene="scm"
                     /locus_tag="IVZ69_000743"
     CDS             42871..>43935
                     /gene="scm"
                     /locus_tag="IVZ69_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP8182851.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSS"
BASE COUNT        12546 a         9240 c         7687 g        14462 t
ORIGIN      
        1 tttacctata ttttctttga agtttgttgg agtaatagta tccaaaatga acacctctct
       61 tctctatacc tctattatga agcgcccatc aaataaagca agcgttgagg aataattcta
      121 tcaacacttg ctttattaag ctttcatttt gtagtttgac taaaaccaat aatcttattt
      181 ctaaactctc gaaaaacttc ttgtggctga taatagtctg catctatttc aaatgtttct
      241 gagaataatt cattgaattt ttctactgaa ataatgattt taccattctt ctctcgactg
      301 ttttctatta tttctgcttc taattcaaat aaatctagtg acgaattaaa atcataaatc
      361 ctgtcatatt gaacaaaaaa atcaagaaaa agttgctcaa actctttctt atttatcact
      421 agtgtttcaa gcagatcaac tttattttct tcagtcattc ttccaatttc ctcactttcg
      481 ttttcaaaaa tcacaaaaat gatattaact taaaagccac taacaaaata agacttacaa
      541 attaaagggt aatccaacaa aataaccatt cgctctacgt actacgattt ggtagtcctg
      601 cctttcaatc ggtaattcat aatagtaatt tactgtttct gatttaccac tttcaatata
      661 ctcaggatta tccaatatca tagcatactc ataaagctct tcaccatcct tattttcaat
      721 cgaccattgt tgcggacgta tcggattttc tgtatcattt ttcattgtat aggtcacttg
      781 taatacacga tcatgctgtg caaattcatt tcttttttcg gtcagttcaa tatttttaaa
      841 tgttagttca accccatctg cctgataagt ttcacctatt tttaaatctt ttgttacaat
      901 ttttattggc ttttcttctg gaaaatacct ggctttaatt gttagataac ttccaaaaag
      961 aatcaatcct agtagcacaa aaaaaattcc tttaacgagc cactgaaacg ggaagtaaac
     1021 tttaaacatc ttttttctcc tccgttttgt atttggtttt tagagaacac gataactttt
     1081 gatcaatacc atccaacttt ttcattatac ttgattctag ttctgaaatt gtttgttcaa
     1141 gtttaatgct ttcaggatca ctaaattttt tatttgattg actagccaac attggtaaat
     1201 ttgaaaccat cacacggaac atatttgctt tcgttccaag agttccttta ttcttctcat
     1261 aaaagctgtc aaacaatttt tttgtttcct ttgaacaata tactttaata tacggatcag
     1321 acattctttt ccctctccct gtttacttaa aaatccatat catattgatt ttgttgtttt
     1381 tgataatcaa ttcctcttgc tgtttcttca tactctctcc gagctttttc aatcgtacca
     1441 tcatcaattg cacgattaaa taaataaaga acacgttttg tttcttgaat ataacgcttc
     1501 ttaaaattac gttttaaagc gggttcagta tcttgaatgt taaattggtc ataatcagtt
     1561 gataaactct ctgcgatatc ataaacaact tttttataca ccaaatttac acatttcttc
     1621 ttatatttta aaggttcctc ttccactgca aatccaaaga attggttttt attctcacca
     1681 aaaacatcca ataaattttc tattctgtcc tctatttcaa atttatattt atcataaaat
     1741 tcttcataat cttttgatga tctaagaaat ggtatattct cattatctaa ttcaaagcgt
     1801 tgcgctcgtt cttgccaatt aaatctacta tccgctctac catttaacga tttaccaaga
     1861 tatcgaatag caatttcagt gagtacctct tcagattgaa tttgctccgc ttttttattt
     1921 tctgtgaaca aatcatcaag ataattcata tcatagtttt gccctaaacg ctttccgcca
     1981 atctttaaga ttaacccatc ttcagaatct aagagtttgt acccaatacg ctgatttttg
     2041 gcaaaccggt aagtctcaat agaatggttt ttcttcaatt ccgcatgaaa atcatcataa
     2101 tttttcgcat actgagcaac ttcagaaaca gctagtttta ttttttctcg atttgaaatc
     2161 ttattttcag ttctaaattc acgttctttc caattttcac gatctgcaac taaatgatta
     2221 tacttataca tatcaagtgg gttaattcca ttatcaataa gtatattatc attccaagcc
     2281 tgcaaaactc gaatatcatt ctttcgaata tccattttct ttcctgttcg ctgatcgttt
     2341 ggcgaaatac caaagtgatt gtgaacatgc cctttgtctg tgtgtgtgac aaccaaaatt
     2401 gactggttag gaaacatttt ttctgcccac ttaacaccca actcatgtgc tttttcagcg
     2461 gaaatatctt ctagtggatc aaagctttgt gtaaaatgcc aaagctttat tttcccttta
     2521 tcaccaaaaa tttcattggt tcgtttaaat tcctcaatag catttaaatc attcgatacg
     2581 ccaattcctg tcacgagttc agaatcttct tgtttattta acatatatga aattgtatta
     2641 tgaatactcc tactttttga agcaattttt ataatcgagc ccataactta ttcaactctt
     2701 tttccaagcg attcaatgga tcacttattg attttatttg tatcattaag tcattttttt
     2761 cagcatatag ccgctttaat cgctcttgct tagttgtaaa agataagtaa acactctgat
     2821 gttcttcttt ttgtatctcg gtatcttttt tatttaactg aacacgcaaa taatttgctg
     2881 ttttcactaa ttgattcaaa tttcttccta ttgctagtaa atgaaaatta atttctttat
     2941 attgtcgatc ggtatatttt agacttttcc ctgcgttgtc tactgcgatt ttcttcacgt
     3001 acattggaac agataaacca aaaatgtctg ctgttttttc tagctcttgg tactgataat
     3061 cgtctactcg aaactttatc ggcctatttt gtcgtcgact atcttcatta cgtttatatc
     3121 gctttctcct ttcttctaat ggtagtttac tgacatcaat tgccatgcgc acttctcctt
     3181 tgcaatatta tttttaagtt caaaagaagc aagcgagggg aaagggaacc cttccccgct
     3241 tgtcgaggga gtaaactccc tacgagcacc ctcatgctcc gcattttatc gagattagat
     3301 agccgataaa tcagctacct aacactttct tcttgcgcct cttctcgata gaaaattcga
     3361 tacgctgtct ctccttttct tctcaaaaat tgttggaatt tcgtttccat caattgatcg
     3421 cttgcaagaa attcgtgtac tagggtaaat tcgctattcg cgaaatttac cgccttttgc
     3481 catttttctt gagtaccttt ttgattaatt tcaaaagttt cttcaaactc ttttactgat
     3541 gaaattcctg ttttttcata gacatacttt cccagttcgg gataaagttt tctctccaac
     3601 tcggcgagtt cttttttcaa atctgcaatt gacttttgtt ttttccttgc catttttcat
     3661 gctccttttt gtatgtgact aagttcattc ataagctcat ttttcatcac taattcttct
     3721 tgaatcatca gttcaatata atttgtgacc gtgatttttt catttgtcgc tttctttact
     3781 gagtcgcata attcggcaag ttctaagaaa tcctgcgtac taatctgtag aattaattgc
     3841 atgacaatca cctctttatt ttttaaatag actatcaaac agcggatttg gtttatcaga
     3901 aatatcctga aacagtggat tattttcata agtaaatcgt tgacgtttct tctccttcac
     3961 ttcttgttct actatcactt tttcattagg tctttctttt cgttcctcga caatatttat
     4021 tttttgcgtc ttatctccct gacttgcttc agctcttgtt tcacgtactt ctaccgttct
     4081 tggttgattt gacgcactac cttgtacatt ttctcgtaca tctactgttc gatttccgct
     4141 ttgactactt gtagtattct gcaagttttc tcgtacatct atcgttctcg gttgatttga
     4201 cgcactactt tgtacatttt ctcgtacatc tactgttcga tttccatttt gactacttgt
     4261 agtattctgc aagttttctc gaatatctac cgttcttggt tgacttgtcc cactactttg
     4321 tacattttct cgtacatcta ctgttcgatt tccattttga ctacttgtag tattttgcaa
     4381 gttttctcga acatctaccg ttctcggttg gcttgtccca ctactttgta cattttctcg
     4441 tacatctact gttcgatttc cattttgact acttgtagta ttttgtaagt tttctcgaac
     4501 atctactgag cgcctatctt gactacttgt agaattttgt ggattttctt tgactgattt
     4561 ttctaatccg gtatttgaat ttttagcttc ttggattctt tctttagtca acgcttcttt
     4621 ttcgtccata ttagcgcctg tacgcccttc tacacgtttc cttaacattt cctcacgatt
     4681 cattgcttca ggcgtgtatt ttgcttcctg tcgcttctga ttaattaatt cttcagcaga
     4741 cttagcttga ccgtgcatag catttttacg ttcttcaata tcttgtttaa ctttttgctg
     4801 aattgcactt gcaggattaa tatttgattc agcattattt ttcattgctt cacgcatacg
     4861 ttcagaacta gacataattc tatcagcgtt ttcaacttta gcgccatctt ttctatccga
     4921 aagacgtgtt ggcatagaat cagcatattt tccagtttca tcttctttat ttttagctac
     4981 tataggtttg ctatttttat taatagcgga catggtacca tcatctaaac cttctttgaa
     5041 tttattcttg gtatcattag ccatatcacg catactctta aatggttttg ttgctctttc
     5101 actagccatt gtagctccat ccgaagctaa gcctgataat ctacgttcac gagcataccc
     5161 aagcgttttc cccgttttat tagctttttg agaaagtgat tgaccaaagt tgcgttcagg
     5221 ttttcgttct tctccttccg cttgatcgtt tccaccacta tttttcccac ctttagatcg
     5281 gttcatacca cctgttcctt tacgaaacag cattgcaccc atgccaaaag cagaagcaag
     5341 ttgcccatag ccttctttga gtccaatatc cacaccaaag taacgcatga ctgttccact
     5401 gcctttgatt aaaacaaaca cagcacagat ataagcaatt gtttttataa agatatttgt
     5461 tgagatacct tcaccagcat ttagataatt gacaaacatt gcaaacatag acaatccgaa
     5521 cccttgaaat ccgactgtca aataacactg taaaatatct gacaaaactt gttttgatcg
     5581 ttgacctgtc tctaagtcag tagcaaatac caaaactcca agtacacgtt taaatgctaa
     5641 ctcgagtatt gctgtaatta taatgaaagc actaaaaaca tacgctactg ctaaagcaat
     5701 caatccaaat gaaattcccc acaaattcgc ttgatagcga taatatcctg atttgatacc
     5761 atcaacaaag gttgacaaaa aattatctga aaatttagta gcaacaaatt cattatcaga
     5821 attttcaact aattcataac gcaggttatc agctgttggg ttctcttttt ccattttatc
     5881 aattacatta tctgtcaata cttgcgtaag atccgttttc caaaaatttt cttttgttag
     5941 attattccgg tcattcgttt tgttaatcat tgaatactga tctgttttat tgatataagc
     6001 taaatcagtg accccttgtt caatcagcga ccacgccacg ccttcgtccg aatttgtaat
     6061 cgtagtcgta tcattataaa atgttttaga aaactctatt ccactgtgaa tcaaagtcgg
     6121 cattaaaaga atcaatgcta ctgacattac aacattcatt ccaactgatt ttagatcaac
     6181 cgttccttta cctgtaatca ttttataacc aataatcact agtgaaagta tcattaagcc
     6241 aacaacaatg gtacttaaaa ctgattgata gactttattc aatccggtac tttctacaaa
     6301 gctaaacaaa tctaaaacct cgggaatcat attttgaata ccatcgacaa tagcgaacat
     6361 tgattttata acagaccagc ctatccacat accgaactgg ctgtaaaaat ttccgttata
     6421 ttttttaaga taattctgat aaagtggatt agttaaaaac tcagtttgac tctcagtatc
     6481 atcaaaccag ttgaaaatac tgccttctgc aacgttactc gtaaaaataa tcatagctat
     6541 gagaataaga aaactaatca acaaccaatt tatttttcta ttatcaatct tttttttaat
     6601 tattttcatt gttacctccc tcagcccatt tttttaggct ctcagaaagc ttctgagcca
     6661 tttttttatt aacgatgatg tgagttacgt aatcatcatt aacagctctt aaatctagaa
     6721 caatagtatt tgagcagata ctctcgatta actcaagagt atctgcgtta tgatcaagac
     6781 agtaaatctt atctactaga tgattttcaa tcaaaataac ccctcccgta gtcaaagttc
     6841 tcaattttat gaagatatcc ctctacttca tttaaatcaa ttctattctt attgctgact
     6901 aacccgttgt aaaattcttt ttgtagatta tatttatctg tttcttgaat ctttttatat
     6961 aaatcaacca gggagtccct gtctttaaaa acttgcttga attgttcgct tgtatatcgg
     7021 ttttcattaa ttgcaacaac tgcttgaatt tcaggccatt tttctttcaa cttaaaataa
     7081 cggggaacgc tgaaatagtt ctcaaaaaag aagtctcgtg cttcatagta ttctctattt
     7141 tgtcttttta tatcctcgac aatttcgtat cgtgtagaga tcttcaaagc tgaactttcg
     7201 ttaatttctg ttccttttcg aaagactttc acttttgaag ggcgttcaat tttataattt
     7261 atcccctttt tacttgaata acttttgata cgaccatcaa attgaaccat atctcctttt
     7321 tttaaccacc caaattttag aaattgttta gttaaattca tccaaatgtg gtctgtgacc
     7381 aactctaagt tatccccttg aacaattttt aaattcgata acataaaagt agcattttca
     7441 tactcttgac caaacttgta tttatccttt ttatatccgt taaattcaaa ggtaccttga
     7501 aatgtatgcc gtttcttatc tcctaatttt ttcaattttt ctctcaaaat aatcaactcc
     7561 atcatttaat atatttttgt gatggtagat actctcgatt aacacaagag tatctgcgtt
     7621 gtaatcaaga caataaattt gatatattaa ccgtttttca atcatattat taatcctttc
     7681 taacctattt ttttcagtgt ctctagcata tccagtctac tagctttttc ttgcttagct
     7741 atgtcctccc agtggttcct agctgtggtg ttgataaact tcatttcatc aatttcttca
     7801 ccgagattca gtttttcatt tatagaatta aaaagtcttg ttagcatttt gtttgttata
     7861 tcaaaatagt cttgacctcg aatttctatt ttatattctc tttcaattga atctttcata
     7921 ctagcaatca acttaagata cttttctctt tgaacttcag tatatctatc acctagtctg
     7981 gtaattattt gaattccttt ctgatttata atattttcaa aaaaggaatt ctgatcttga
     8041 ttaatctctt ctatactatc cttatcttga ttagtttgat cttgactatt ctgatcttga
     8101 cttaactgtg tatccgattt gacgtcgcat ggtataccag ctggatacca tttttccatc
     8161 agatcaactc ttaatggttc tacttgacca gactgcaaaa tcatatcaaa ttttattggc
     8221 tttagctttg agaaaaattc tggttttaag ttcaataact tgaatcgata aatagaaggt
     8281 ttatacctat cgattcgtat attttgattt tgtaaccagt ggggtagaaa cgctaacaaa
     8341 tcttcattta aaaaaaatac aaaacctttt gtaaaaagta tctttacatc atcatcgggt
     8401 gttccgagca ttttcgtgta tggataagct tcgacaattc cgtcatcatc tgcgtttgtg
     8461 ttcagatata cgtataataa ttttgctgaa tctgacatct tcataaaact tgcattattt
     8521 aaaaatgatt tagccagcat tcgtttttct gccataaaaa tcacacttct tcctatttga
     8581 atgttaaaat gtagtcaaat aaagtttagc tagaacttta ttattgagcg ttcctagtgg
     8641 tctgcaaact aacgggaaca ctctttttta ttcttattaa aaccagcaat actagttcac
     8701 cttctttcat ccttttacat ccaattaaat ttgatgctgt agcatccatt tttttacctc
     8761 ttcttttgaa tatagttcaa ttgtgtcaac cacgataata ggtaatccta accttttaaa
     8821 cttcagaaaa gttccatatg atacgtttag aaattttgcc atttcttttc ccttaagaaa
     8881 aggtcgttct aatccgctgt ctattcttgc ttgatcaata gcttcttttg tcacttcaaa
     8941 cacatgtgtc ttcaactgat ttgtttgatc agtattcaac attacactga ctccgatttg
     9001 ctccattaaa aattcccact ttcatatttt catcaataag ccaactcgcc aagttgtttg
     9061 ttaataatct gatttcaata accaacctat tattttttga taaacatttt tcgacacact
     9121 ttgaacttcg aagcattcaa tttttttaag agtttgcctt gaaattccaa ttaattctgc
     9181 tgctttagtt ttcgtaatca tcaactttcc tcgtctctct cgaattctta tactaaaatc
     9241 ctcattaatt tgaaacataa acatccctcc atttttattt ttgcatttat ccgtttatcc
     9301 gatgtcggat aaatagattt tagtatatat tattttgata gtcaattaaa aatatacatt
     9361 ttggataaaa ttgttcattt ttttatccaa atcatatatt atagatagta agaggtgaac
     9421 ttcattgact caaaaaaaca gaattaaaga aactcgcgaa gaacagaatt taacacttaa
     9481 agaacttagc aatctgtcgg atattccgta tcaaactttg agaaactatg agattggtaa
     9541 aagaaaaccc agaaatgatg aagtttggtg gaagttaggt acgattttaa acgtccgtgg
     9601 gccctactta aaaggagaag atagttttaa aacaaatgat gaattgcata tttattatct
     9661 aaaaaaaagt catacaaatt ttgaactgtc taagaaagaa gaaattatag atataataga
     9721 taaactaaac gaagacggtt tagatgaagc cttacggcag ttagcactat tatcaaaaat
     9781 agatgatttc aagcggtaac ttacttatca tcatgtagac tatcaggtat cataaactaa
     9841 ttcctcaatc agccaactcg ccaagttatc agattggaga gattagttat gtcaatacaa
     9901 aagtacaaaa caaaaagcgg tacacgatat agtgtccgct tatatgttcg taaagatgaa
     9961 aatgggaagc aagaatacta tgtaaaaaaa ggcttcaaaa ctgaaaaaga agccaagtta
    10021 cacgaagcaa gaaaaaaggt cgagattgaa gatatgggct atcacagacc ttctaatgac
    10081 ttatttagaa cagtctatga agaatggttg ccgtcttata aaaatcgtgt acaagaaacg
    10141 acttatcaac gaacaaaaga cctttttcgc ttgcatatcc tgccaaagtt cggagacaaa
    10201 tcgatttcta agattactcc tatttactgt cagaatgcaa tcaatgaatg ggctgtaaaa
    10261 tatacaaata tcaagcaact taaatcctac agctctcaaa tatttgagta tgcaatcttc
    10321 gcagaattgt tacagcgtaa ccctatgaca aataccaaac tgccaaaaca agaaaagaaa
    10381 gaatccgaaa attatttctc actagaagaa ttaaaagagt ttttggaaat tctcaataaa
    10441 gaagagtctt taaaacatat cctgatcttt caacttttaa ttactaccgg tgttcgcaaa
    10501 ggtgaattat cagccctacg ctgggcagat attaattttg aagaacagtt actacacatc
    10561 ggaaaaagtt atgcaacaat tcgcactgaa gatccgaatg ctactagaaa aacaatcagg
    10621 attcagaaga atacaaaaaa tgtctcttcc gaacgaattt taccgattga tactcaaacc
    10681 atcgaaatgc tgaaactttg gaaaaaagag caagcagagg tacttttaca attcggcatt
    10741 aatgcaaata ccaaaaagca acttatcttt acctatgtaa atgcaaatgg cgatgttaac
    10801 caacctttac acgcagatta ttccaataat attatgagac gtttagagaa gaaatataaa
    10861 tttaagcacg ttactattca tggattgcga cacactcacg ccactttact tttagaaggc
    10921 ggtgcgagca ttaaagaagc acaagatcga ttgggtcata aaaatgctga aactacgctc
    10981 aatacttatt cccatgtaac tgaaaaagcg caacgaaatg cggtagacaa gtttattgct
    11041 tacactggat tatagacaaa aaagttgccg tcattacctt tttcattacc acaacgaaaa
    11101 aaagcacctt ccaactgaat ggaaagtgct tgaaatcgtt ggtataacaa cgattaacgc
    11161 ttagagaatt gtgaagcttt acgagctttc ttaagacctg gttttttacg ttcgaccata
    11221 cgtgcgtcac gagtaagtaa gccagcacgt ttaagagcta aacggaagtc aggatcaact
    11281 tctagcaatg cacgagcgat accatgacgg atagctcctg attgtccagc gtatcctccg
    11341 ccgtttacgt taacaaatac gtcatatgcg ccttttgttt cagtaacagc gaaaggttga
    11401 ttgattactt cacgcaagtc agcatgtgga atgtattctt caacatcttt tttatttaca
    11461 gtaattttgc cagttcctgg tactagacgt acgcgagcaa ctgcgttttt acgacggcct
    11521 gtgccgatat attgaacttg tgccaatgaa attccctcct attagattaa gtttgtgatg
    11581 tctaaaactt ctggttgttg tgctgcatgt ggatgttctg ctccaccgta tacgttcaat
    11641 tttgtaaatt gtttgcggcc taaagtgttt ttaggaagca taccttttac agaagtttcg
    11701 atcaaacgac gagaattttt agcacgcaat tcgccagcag tgattgattt caatcctcct
    11761 gggtagttgc tgtgacggta ataaattttg tcagtcgctt ttttacctgt taatttcact
    11821 ttgtctgcat tgatgacgat gacgaaatcg ccagtatcca aatgaggtgt gaaagttggt
    11881 ttatttttac cacgtagtac agatgcaaca actgttgaaa gacgtcccaa tggaacatca
    11941 gttgcgtcta ctacatacca tttacgttct acttcgcctg gtttggccat atatgttgta
    12001 cgcacgttat tttcctccaa tttaagttct gatgtttgac atacacttcg agtttccggg
    12061 gctctttgtg gggcaaacaa taccatttaa catattaccc gctaatctag tcaatgtcaa
    12121 cgtttttctg cttgattgaa aaatttatat gaaactttac ttcttttctt tcttttatat
    12181 aaaagggtcg tttcctgtca aaatgaaaaa caaaaagagg ctgtgacaaa agtcttgtca
    12241 caacccctta ttttgaataa acggtgttct cctgccaact cctcggtcac aagtcacaat
    12301 atccataaaa cataagaagc tgttttttaa aattgtttct tgtgactcgg agctgaacgg
    12361 caggcttaca acctcttggt aaacggtgtt caatcagctg accctcggta ttagctcaaa
    12421 aaacggcaaa atatgaggaa ctattttgac gtttgtttct ctaatactca ggtcaaaacg
    12481 ctgatttcac aacctctttt tcggtcaagt tcaacaacag tttttacgcg tcgatctctg
    12541 gcgctttgcc caaatgagct tggatcatcc agatacgttt ttctgtggct gttttgaatt
    12601 cgataaagat atcttgtgtt ggatcgtcgc cttcttctcc agaaacttcg attccttttt
    12661 ggtaaagatc tgctagataa cgatagcctg caacaagtgt ttccaaacgt tctggaatag
    12721 tacgatccca gcggccaatt tcatcaggga tttttgtgtt atctgcaaat tcacgcaatg
    12781 tagaataagg tgaaccgtct aatgtgatca agcgttcgga tacttcatct aactgagcgt
    12841 tcaaatcatc catgaactca tccatcattg ggtgcaatgt aaggaaacct ggtcctctca
    12901 tgtaccaatg tgtttggtga acaacaacag acatttggct tagatctgca actaattgat
    12961 ttaatacttc tttggtttgt tggaatttca tctttcttgc ctcctaacat tttcttacac
    13021 ttaaaataat agtagacttt caatgaaaag tacaacaaaa tcatttacct gagaacgatt
    13081 ttcagttcgc ttttttatcc gtaaagccaa tcatttttca gaatcagcta attcttctcg
    13141 cagttgagca aattgctgat aagtctgtgc taaatgcttt tgtgtcgaaa caaataatgg
    13201 atagattttc tgatattttt tatgatcagt ttcttgtact ccaacttgct ctttcaattc
    13261 tatcaattcc tgtgcttcac tgatactttg gatctttccg atgcttctcc agcctaaaat
    13321 cacagctcct aatgcggatg cttctgtgac agtagggaaa acaagcgggt aacccagtac
    13381 atcagccatc atctgacgaa aaatcggaga ttgagcaaac ccgcctgtag cacggatctc
    13441 tgtgagctga ttttcctggc aaactccttt taaaatccga taaaggttga gacagatccc
    13501 ttctagaatc gccttcatca tttctttttc tgtatgttgc cgctgtaaac cgataaaact
    13561 gccaaacgca tctgcgtccc aaagcggtgc tcgctcacca agtaaatagg gatgaaaaat
    13621 cagaccattg gcacccgctg gcacaaaagc gatagccgaa agcagtgcat catatggatt
    13681 ttctcctttt tctttagcag attgaacgac ttcctgtaaa aatgtatgcc ctgcccaatc
    13741 aaagatgcca gcaccattgc tagtcgctcc tcccactacc caatgtttct gatccagaac
    13801 ataacaaaac gtctccattt ctggatggaa ctgaggctga gtagtaataa aacgaagtgc
    13861 tccgctcgtt cctacggtca aagcggcgat cgtatcacca aaagcaccta accctagatt
    13921 agaaagcggc ccgtctgccc ctcccaaaac aaatgatata tcatttggca aacctagttc
    13981 tgctgctgtt tttgatggta gacctgttac ttgataggtg gaaggaaaga cttgcggcaa
    14041 ttgctctatt cgaatgttca agtagtcaag cacttcttct gcccattgga attcatggat
    14101 atcaaaatat ccagttcctg aagctgttcc gtagtcgctg atcagttcgc caaacaatct
    14161 ataaaagata tagtctttga taccgacaaa ataagcagtt tttttgaata attcaggttg
    14221 gctgttttgc agccacttga ttttgttcaa tggtgtcatt ggatgaatcg gcgtcccagt
    14281 ctgccgataa aattctttgc caagcacggt atatttcagt ttttctgctt cgtccgctgc
    14341 tcggttatct gcccaagtga tcattcgaga taacggtgtt ttctcttcat ccaacaatat
    14401 caggccatgc atcgcagagg agaaggagac aaattgaatg attgtgtctg aaggcaactg
    14461 tttaattact tcttttataa cggtgcagac accttgaaag atcaattcct gatcttgttc
    14521 tgccatccct tgtgtttctt ggatcaaagg gtagcgaaaa taagcggatg ctgcttcttg
    14581 ggcttcatct gtgaaagcaa ctgctttggt ttgtgtggtt ccgatatcta atccgattga
    14641 aacgttcatt ttttcacctc aaattttatg tatgtacaaa aatttagttt aagcttgcgt
    14701 atcttggttt tgaaaagggg gagatggcgt gttactttat tttatcattg gttgctgtat
    14761 cggatcattt ttatgtttaa ccgcccagcg gattccgtta ggtcactcta ttatttatcc
    14821 tagatctcat tgtgtcaaat gctgtcgttc gctttcttgg tatgaattga ttccgattct
    14881 ctcgatcatc gtccaacgat ttcgctgccg ctattgcagg tgtcggttgc ccttctacta
    14941 tttgttggca gaagccttat gtggtggtct ttttgcctgg ttctttactt tttcttccgc
    15001 aagaaatttt tcgacgttca tatggatgct ttcggctttg ctattttcgt tgatggattt
    15061 attttacttc atggtccatt ctcacacgct attctgttct tgggcaattt tatggatttt
    15121 ttggttgcag gccggcgtct tccaatggca aagtgtgctg ttaacgttta tcgtaggcgg
    15181 tgtgtgcctt cgctatggtc aatcctatct cggagctggc gatactctgt tgatgctttc
    15241 ttggagtggt ggcttgtctc tagaagagtt gcttcagatc ttgtttcttg ctagtctgtt
    15301 tggaatatcc gttttttctg tttactttat ctgtcataaa aaaaagttgg aaaagctgcc
    15361 tttcattcct tttttgagca gtgcgttgct gattgtcctt catcttaggt attgaaaaaa
    15421 ggttgtgaca aacgacttgt cacaacctct gatatatagt gttctcttac caaatccttg
    15481 tgacttggag ctaggcgaca ggttcacaac ctctccacta aatggtgttc aatcagctga
    15541 ccctcagtat tagctcaaaa tgctggtttt acaacctctg atatacggtg ttccataagt
    15601 agctttttcg gcttcttatt tcttgacgcc ccaatgtcga cgaaggaaac ctgcacgtcc
    15661 agaaccttct cgataaagat tgtaatggag cttgtttttc ttgtaataat cctgatggta
    15721 atcttctgca ggataaaatt cgcttcttgg ttcgattttt gtcacgattg gcttatcgaa
    15781 tcgcccgctg tcttgcaatg cttgttttga acgctctgca atatttcgtt cttcttcatc
    15841 attatagtag atcactggac gataagaatc accgcgatca gcgaactgtc ctaatgcgtc
    15901 agtcggatcg gtttgctgcc aatagatttc caccaactga tcataagaaa taacttctgg
    15961 atcatattcg atctctactg cttctgtatg ccctgttgtg cctgttgtta cttgttcata
    16021 agttggattt ggtacatgcc cgccagtata accggatgtc acagaaatga tccctggctg
    16081 ctcttcaaat ggtttgacca tacaccaaaa gcatccgcct gcgaaaactg ctttttttgt
    16141 catataaaat cccccttttt tctcatcata ccttgatttc caaaaggagg ataacgtttt
    16201 gcttgtgaca gaaaaaacgg aaactattat atacgtgata cggcttctga taaatgccaa
    16261 aacgaacgta cttgatcaaa aacggttaaa tcaggaatca catattcagc agaaggaaga
    16321 tttatgtttt cacctattcc caatacatgc atgttaccag ccaaagctgc ttgacaacca
    16381 gcttctgaat cttcaatgac caagcatgca tttggcggta cattcaattg ctgtgctcct
    16441 ttgagaaaaa cttctggatc aggttttgct tttgatactt gcgtgccgtc aataaggaca
    16501 tcaaaataac ttgtcaaatt cgttttttct aaaatgaggc gtgcattttt gcttgctgat
    16561 cccaatccga tcttgatgtt tgtttttttc aagtactcaa gaacagctat tgcaccaggc
    16621 aaaacggatg tttcatccat tttttgaatc gcttgaagat atagattgtt tttttgctca
    16681 gcaaaggctg atttctcttt ttctgagaat ttctgttcca tttttccaaa tgacagcaat
    16741 cgctctagtg actcggttct ggatattcct ttcagttgct cgttttcttt ctcagtgaat
    16801 ggaatggaca gctggttagc taaaaccagc cacgcttcgt aatgataacg agctgtgtct
    16861 acaagaacgc catctaaatc gaatagtgct gctttgattt tcatcgatta cctccttgaa
    16921 aatgaacgac ttgaagtaaa gatgcgatgt ttttagctgt gcgatgaaga ttatcagtgg
    16981 cttgctgtaa agcttcttgt aaaggcacag ctgcaggaag gatcggaaaa acggccgaaa
    17041 tgccaacatc tgctgctttt tcgcttcctt taccaacact tccgcaaata gctatcacag
    17101 gaacgccctc tggtactctt ctagcaatcc caactggcgc ttttcctttt agactttgtc
    17161 catctagacg tccttcgcct acgattacga ggtctgcttg ctgtacccgt ttatcgaact
    17221 ccagtaaatc caatacgtag tcgatgccag agactatttt ccctgaagca aatgctaaca
    17281 gtcctgcacc cattccacca ccagcactac tgcccgatgc ctcgattact tgaggggcaa
    17341 atctcatata aaaatcatgc atggcttggt cagccactgc taattcattt tctttcaagc
    17401 ctttttgtgg tccgaaaaca aaagaagcgc cttcttttcc gcataaaaga ttagtaacat
    17461 cagtaatgac agtgattttg gctttaatca gctcaatagg cacgttcgtt ttatcaactg
    17521 tagcaatttt acctagattt tctcccagtg cttctacttt ttgattatct tgatcgtaaa
    17581 aagcataacc tagaccttct gccatgccga tgccgccatc gttggtacta cttccgccaa
    17641 cgccgatgat gatgtgtcga acaccttgtt gcaacaattg tcgtatcagt tctcctactc
    17701 ctcgcgtgga taacctaagt ggctgttgtt ggtttagtgg gacatctttc aatccgacga
    17761 tttctgccat ttcaaaaatc gcagtttgac cgtctgaagc gtactggatt tctttgtttt
    17821 tgccaaatgc attagtaacg actgctgttt gccgcttcaa ccttaaactg tctgctaatg
    17881 atgaaaccgt tccttctcct ccatcgccta taggtagcag atcatattca gcctgaacaa
    17941 aaacttcttg aaaacctgat tgaatggctt gtgctgcctc taaggctgtc agactttctt
    18001 tgaaagaatc tggcgcaatc agaatacgca ttattttccc ctccgttcca agatcagttc
    18061 tttttccagc tggtattggt ctccattgac aaaaataggt aatgtttctt tcgtctcttt
    18121 ttttattact atttgttttt ttgtcaaaac aaatagcaac ctgtgatttt tccaaataaa
    18181 aggaaaagaa attttttccc atgctgaagg aagtcttgga gaaatagaaa gagttccatt
    18241 cgttactgta atacctgaaa aaccaaatat aactgctagc catagtgctc ctaatgaagc
    18301 agcatgaatt ccgtcatctg atgaatgcgg atctggtcct aaatcaatca ggcacgcttc
    18361 ttggaataaa tgatacgccc attccatttc ttggatacgg caagcctcta tggcgtgaat
    18421 cgctttactc aacgatgagt cgtggattgt tttgttttca tagtaatgca aattcttaga
    18481 aacgattggt tgagaaaaat actcaggtaa taagtataac agcatgacaa gatctgcttg
    18541 cttgctgact tggagttcat ttacttcgct acgggcataa tcaagtaaaa tagactggct
    18601 gccaggacgt tctttgtaag tggtcaaatc aataactggc ttactgagat acgtgtcatc
    18661 ttgcggaatc agctgttctt tgttaggcac tggcaaatat aacttatcta aaaaattttg
    18721 acattctttc aaaaaaagcg gatcgccagc ttgatattta acagctaagg ccacattata
    18781 atgcgccaga tagttcgtat atgcattatt gtcgatatat tctgtgtatt catctggacc
    18841 aatgactctg tgtatctcta aatgatcatc gacttttaca gctctgctca gccaaaaagc
    18901 tgctgtttca tgaatgagcg tttttccctt tgtttctaaa aacgattgat cctctgttgc
    18961 ttggacatac tcttgaacgg cataagcaag gtctgcactg atatgatgtt ctgcggcagc
    19021 tgaagcaact tcttgtcttg ttccggtttt gatattcaat gcagcaaatt tgggtgtctc
    19081 ttcctgacca gtgtgtgcgc tttcccatgg gaaaagtgca ccttgatagt gataatctct
    19141 tgctttttgc cgtgcgcctt ctaatcgatc ataacggtac agcagcaaat tctttgctac
    19201 ttcaggaaac tgatataaaa agaaaggcag gataaaaatt tccgtatccc agaaaacatg
    19261 ccctttataa ccttcgccag ttagtccctt cgcccctaca ctaacacttg gatcattgcg
    19321 gggagtcata atctgtaaat ggtaagcagc gaagtccatc gctaactgat cgaaagaaga
    19381 atcgccttgg atcgttatcc gatgctgatg ccaaaaatct gtccaataag acatcgactg
    19441 ctctaaaatt tctgtataac taacgctttt ctgggcttgg gcaatacttt tcttaaacgg
    19501 gtctgtttgc tgaagagagg tagagagcac gatgatcttc tccagcgtaa aggacgtatt
    19561 ttttctgatc ttttctgaaa aggaagcggt gatccggcga ttttttgctt ggaatacacc
    19621 tgctttattg aatttagctg caatcccaat atcaatttta ctttctgttg tctggtagga
    19681 tgcactgatc aaatcgtcac caaatactcg cagttctttt tcaaccaact gctgtgtacc
    19741 aaaattggtt tgctgtccat cgatacccgt tttcacatct acttggcagt cttcggtcaa
    19801 cggcttgatg accactttca gggctgcctg atggagatta ttttgatcag caacacgaca
    19861 agtaatgact tccacttttt ttccttgagc agtttcaatg agcgcatagc gtttaagctc
    19921 tcccatttct aaatctagtg cccgctcgta tgcaagaact ttcatcgtct caagagaaaa
    19981 atgttcaccg tcgattttta tttcccatct gatgacatct gggagattca ctaactcggc
    20041 tgattctgct cctaaaggtc ggttatatac accagctgca aacattcccc ttacttgatt
    20101 ccgatagtct tcctcctggc ttcctctgat accaaaaaat ccatttccaa tggtcatctg
    20161 actcgcatac ttattgatat actctaaatc aaactgtttt tcttctactt tcataaggta
    20221 ataacttctc ctgtttctgc cgaacgatat aaattttcca ccagattctg gatgacatat
    20281 ccttgccagc catctgcaat catctgagtc tggtcaccga gcgcccgatt cacaaaatga
    20341 gccatactta gttcatgtgg gtcattaact ggcgtggtct tttgtaagga aaccagcttt
    20401 ccatctacat cttcgaatag ttcgcctgga tacagattag cacctgcctg atcgccacaa
    20461 aaagccacat tcagtttgtc ttctctgata ttcaaagcaa acgaagtatt cagttggatg
    20521 atcttgccgt tttctaattc cagtgtgcca aaaattgcat cttctactgt gaatttgctt
    20581 ggatcccatt tcccgaattt ccctgaattt tttttcgtac caattttttg gaagctgtac
    20641 gcccgaacgc tttttacttt aggaaatcca gtaatataca tcgctgtatc aagcatgtga
    20701 atgccataat cgatcaaagg cccgcctcct tgaagttctt tgtcgataaa cgttccccag
    20761 cctggaacac cagaccgacg aagcgcattc gcttctacgt aataaatatc cccgagaaca
    20821 tcaagatgat tcttgatcat tgttgcttcg tcagaaaaac gatgctggaa tccataagcc
    20881 aaaatctgcc cgtttttatc ggctgtctct gccatctttc ttgcttgatc agctgtcata
    20941 gctggtggtt tctcgcacat cactgaagca ttagcttcga gggcagccaa tacatgttcg
    21001 aagtgaaagc gattgggtgt acagacactc acgatatcgg gagaaatctc attcagcatt
    21061 tgtgtaactg atgtatacgc atgagaaaat cctgtacgtc ggcaaaagtc ttctgctcgc
    21121 tggctgactg gatcaaccac agcggccaat tctaagacat ctgatctttt ttgataataa
    21181 gcagcatgta ctttttctgc tacttgtcca gcgcctatga ttgctacttt cttcatttat
    21241 ttctctctcc tttgcttatt tacttattgt tattctttct ctattctttc tctaaatcat
    21301 ttaaatgacg cgctgtttcc agacagtttt tcaagtattg caatgattcc tgataaattt
    21361 tcacttcatt ttctcctcgc aaacgacatt catataccat ataaccttca tactcatttt
    21421 gaagtagcgt ttgaaaatgg cgagtaaaat caattgcgcc agatcctggt tggtagcgat
    21481 gattatctgc taaatggata tgacccacat actctttttg cgtagtcaat gcttttgaaa
    21541 tatcatcttc ttcaatattc atatgataaa aatcagcgat gatctgcaca tgtttcaatt
    21601 gattagagtc aatgtaatga cgcgcatccg ctaacaaatt gatcatatgg tcttggtatc
    21661 ggttcaaagg ctccaaataa ataaccgtac ctgtttcttc ggctacttta tctaaataac
    21721 gaagtgattc gctgactgct ttatagtctc cttctttgct tcggggtgaa accatcggcg
    21781 gtaatcgata agtgaacatt ccccaagctg ctgggataac gattcctttg cctccaacct
    21841 cgcttagtgc acgcaaaatc tcagcaattt gacgtacacc attaagacgc cgttcttcga
    21901 taaagtcacc gatccaccca tcgtagccgt tacaagctgt cactactggg atccctgttt
    21961 ctttgattgc ctgtttgact gtgtcgatat tttctattaa caacttaccg tcgatttcgt
    22021 attcttcaaa tccacagtct ttgataaatc taaatttttc taaaatgtct cttgggaaaa
    22081 atgcttgatc ttgcgtaccg aatttcattg ttctcctcct cggacttgaa cgcccatttt
    22141 gatactttct tctgggtgct ggtctacata acgcatgtaa gcttctgcgc tttctgcaaa
    22201 tggcacaact ggatcaatga tttcttcaca atccaagtaa ccgttcatca ataattccca
    22261 acatgtgtcc tcgattcgtt tacggttcca tcttgggtaa tctgggtttg gttcactaga
    22321 tgctcgagca aagacgattt ttgcattatt gaaatgtgct tcgcgaccaa gattaaaccc
    22381 agctggaaaa ggtttagcaa aggcaacata agaaatgatc ccgccatagc cgatccctat
    22441 taaagaagct tgtaatgcgg cagcactgcc actcgtttca ataactgaat ctactccacg
    22501 tttatctgtc aattccttta gacgaaaacc gacatctgct ttcataggat ctagcgtgta
    22561 atcggcaccg tgtttttctg ctaattctct acgctgcgct atgggatcga tcccaacgat
    22621 ggtagtagca cctgcttttt tagctaattg aatcgcaatt tgcccgatag cgcctaaacc
    22681 gaagattgct acagcatcac ctgctcgaac atgtgcttcc cggataccac ctaaagcgaa
    22741 ttgagcagga tcgtaacata ctgcattttt ccattgatcc aaccgatcaa gtttacgtag
    22801 tttataatta tcaacaccgt ttgtaatcag cgtttcacga atgggtccat aagtgcagac
    22861 taactctcct ttttgatact ctgtcaccaa actgcccgtt tcttcgatcg taccgacaat
    22921 catatttcct aattgaaatt cgccaaatac cacaccgcgt tggcttcctt cttctcttgg
    22981 caagaatagg cgccattctt ctgaaaattc ttcatcgata aatggactta atcctctaaa
    23041 gtcgacaatt tctgttcctg gttttggagt agcgaaaatt actcggatac gtacttcgtt
    23101 cttttcgatc tcacggtctt cgtaatcttt gaatccggct attcttggtt ctaatgcaac
    23161 taattttttc atcttttctt tcctctttct tttcttttta tccttttacg ccgccttcga
    23221 ctaaatcacc tttaataaat cgttcagata acgcatacat aatgatgact ggtaaagcgg
    23281 tcaccaatga agcggccatc attcgtcccc aaatgtagtc tggtgtactg aataatgtgt
    23341 tcaaaccgat tggtaaagta aatttttcgg aggtcgacag gaaaatcgaa gcaaataaat
    23401 aatcattcca cgaaaccata aagcaataaa cgaagacaga aatgattcca gaaatagcca
    23461 atggtataat gatccgaata atgatctgga tccggctaag accatcgatc attgctgctt
    23521 cttcaatatc agtcggaatc gtgtcaaaat aactttttag catgaatatc gcagtaggaa
    23581 gtgtttgaac gaccatcgtg ataatcagtg ctgtattggt atcatacaaa cctagaccgg
    23641 aaatgatttt aaataatgga acaacgatca aaataccgga aaacatataa acggtgtaaa
    23701 agctagcatt gattttcgag cgagctttga agcgtagttt tgacaaagcg tatgccccgc
    23761 tgatcccaat cactactgca gttacggagg ctatcaagga gatcactaaa ctatttttga
    23821 aatacatgat gaatggaaaa atctcagcat tgaaaatatc ctgataatgt tcaaaagtcc
    23881 attctttcgg aaaaatagtt tgtgtcgttg caattgcttc ttgtgaatcc ttgaatgatg
    23941 tcatcagcat gatcaaaaat ggaaacaaat tgacagctaa tagcaacaaa atcgtcgcgt
    24001 aaaataagat tttcctgctc tttttatttt tcatttcaag tccaccttct ttcgtgagag
    24061 caagacgacc gctgcaataa tgatgaacaa tagaatcgat atagctgctg cttttccaag
    24121 atcattgaac gcaaaggctg tctgatacaa ataaacgcct aagatattga ctttattcgt
    24181 cagtagatag acatctgtaa acatatagaa catccagata gatcgtaaaa caatcacagt
    24241 tgctagtact ggtttgattg ccggcagtgt cacgatcttg aacttctgcc aagcatttgc
    24301 accgtccatt tcagctgctt cataaagcgt tttgtcgact gtttgcaaaa tagccaaaaa
    24361 tgaaataaac gcatacggat agtatctcca gatagcaaac aaaacgacca taaagaagct
    24421 agcaactggc tggtcgaacc acagcggtgc ttcgttgaaa agctgcaacc tatctactaa
    24481 cagatcattg acgattccat aactattatt gaacatatat ttccaagcaa aaatcaaaga
    24541 aatagatggc gtaacataac ttaataaaat cagtgaacgc accgttttcc taaatctgaa
    24601 cttgcggtta agcaaaatag ctacggctaa tcctaaagct gtactgcctg ctacaactaa
    24661 gaatgtgtaa gcaactgtta aacctaaaga acgataaaat tcactatcac ttaaaatttc
    24721 aagataattg cttaatccga taaaaacggc gtctgagtta ggattcagcg gcatatcgaa
    24781 aaaactgatc tgaatattgg aaagcattgg aatcagcact aaaacagcta ataaaagcat
    24841 gcttggtgct aaaagtccca tggctaattt taagtcagaa tgtttccttg gacgattcat
    24901 tgaaacctcc ccctgataat ctgccaatag ctatctactt ttttcgaaca ccattggcag
    24961 aacttcttgt tatttcgtat ttttttgtgc gtcagctaaa gcttgatcga catcttcgtt
    25021 tccgacagtt acttggttca ctgcttttcc gatcacacct gagcttgtga tatctcccat
    25081 tttcgtgaaa ttcttttccc cgactagtcc aaagacttgt acttcatcaa aagcactagc
    25141 aatctcagat ggcagctcgc caaaagactt gatgacttca ttttctttgt aaccatccag
    25201 ttcgactact tgtttattca ctggttgagc accaccagga gacatcaaga cccacttttc
    25261 catgtttttc ggttgagata agaaagctgt gaatgcttca gcagcctctt tttgtttctc
    25321 gtctagacca gaagaaatcg tcaatccaga tactgtgcca tagacagctt gatctttttg
    25381 tgttgggata gcaaaaccga tattttctga gttccccgct tcataaacag aaggcaaaat
    25441 gtaagttgaa tagattgcca ttggtgctgt tccattcatg aaagcatctt tgatttctgt
    25501 cacatcatta gagcctggca tcgtgtattg ggataagttt tgataaaacg acaatgcttc
    25561 tctcatcttt tccgtatcga tcgttacctc gccttcatca tccaaaacat ttgctccatt
    25621 tgacaaagca aattgagaga acgcttgctc actcattgtt ccttcagcag taggcatagc
    25681 aattccatat tgtttattct ctttatctgt gaaatgttga gcaattttta aaatatcatc
    25741 ccaattttct ggttctgaaa aaccagcttc tgataatttt tctttgtcat accaaatacc
    25801 ttgaacccag ccgctaattg gtgcagcaat atagcttttt ccatcttctg aacgaacaag
    25861 gtttttggct ccgtcataat aattatcttc tccagcttcc tcgataacgt tttggactgc
    25921 cgtctgatca atcagttcat ctttatccat cactttagca aaatcctgac tgacttccat
    25981 tacttctggt aatttaccgg aacgagctaa cgtaacgatt tttgtattga acgctgattc
    26041 ttctaccggc acttgcttga ttttgatgtc tggattttct ttttcaaaat cagcaaccag
    26101 ttcattgatc acacttaatc gttcctgttc gacagaagag tgcatgaatt gaatcgttgt
    26161 ctgttgtgat tcgttagagc tttgactttc accacaagca gtaagaagaa atccagtagc
    26221 tagcagacag gtagtaacaa taattttttt catttttttc cacctcttat tttattattt
    26281 tcagccacat atattcatac ggctggaata tcaactttcg ttcttgactg caatggataa
    26341 tttgtccaga aaacaggtct aggtaatctc cttttggtaa aagataacct gctgattgat
    26401 tggaaaaatt atggataact aagactttct cttccttcgc ttcgcgaata aaactgataa
    26461 aagaatctgc tgagtccagt aagtaaatca aactattcgg atggaaggct ttttcttttt
    26521 ttcgaataga tagcatctgg gtcaattcac catatactgc tgttcttaat ggatctgtct
    26581 gcaactcttt ctcaatatct gctaacaaaa atttttgccg attgattttt cgattctctc
    26641 ctgttttttc tacgcctttg taatcatttc gacttcccag cacactttga atataaattg
    26701 ccggcacgcc tggtaacgtt accaaaaatg aatgagcagc taaaaagcgt ttgcttctcc
    26761 attccgtcgt atctgttgga gaacttaacg catctagata cgtagcgttt atctcatatg
    26821 gactggtcgt tccatctggg tttttcttgt agtttactcg ggcaccctct ttcttcagct
    26881 gttccactaa ttcaaggatc gttttttccg gcagaatacc tcgtaccgga ttcaatccga
    26941 taccgtcatg ggaggctaaa aaattaaaaa aagttgtttt tttcgatgcg aaatcgatgg
    27001 tttttaacca ttctttcaac ttacttgtat tacccgaacg aatcgcttga agggtcaaag
    27061 gtggtagcga aaactgatag accatctgtg cttcattctc gccattccca aaataactga
    27121 tattatcttt gtgtggcaca tttgtctcag tgatcaatac cgttcctgga gctgcttcat
    27181 cagcgattgc acggaataat tggatgattt tatgcgtttc tggcaggtgt atacaagaag
    27241 ttcctagttc tttccataaa aatcccacag cgtccaagcg aataaatgaa gcgccttttt
    27301 ctaagtaaaa caaaagaata tcgatcattt tcaataaaac ttctggattt ttaaaattca
    27361 agtctacttg atcttcgcta aaagtcgtcc atacgtgttt ttctttcccg tttttgtcaa
    27421 tgaacgttgt aagtaacggg ctggtccttg gtctagtcac gctgcttgta tctgtatcca
    27481 gtggcaaatc aataaaaaaa tctttgtacg tatcattcaa gtttaaatat tcctgaaacc
    27541 aagtactttc ggcagacata tgattgcaga caaagtcgaa cattaaccgt gtttcgcttc
    27601 tcatttcttc tatatcttcc catgtgccca aacggtcgtt gattgcctga taatttacaa
    27661 cggagaaacc atcatcagat gtatatggga aaaatggcaa gaaatgtaca actctaaatg
    27721 tatctgccaa atacttttga taaaatttct taaatgtacg caaagttggt tgctgctctt
    27781 caaaaaattg atccccataa gtaatcaaga aaatatcttc ttcgtcccaa tgcagtttgc
    27841 ctgcctggcc tttcttctgc tgataaacac tgactttttg ttcaatcata gaggcggttt
    27901 tctcagacaa atctgagtcg cgataaatcg cttgtaaaag ttttgtatac atcggattcc
    27961 cctttctttt ttgggagcgt tcccaacgat ttgatcatat tatggaaaac gcttactgtc
    28021 aatagcattt ttttaaataa ttttgatata cacaaaaata caaataagaa agcttatgta
    28081 tcaataatta atagcttctt aaaaaaatat ggtctctcat gatcatgcaa gctattccta
    28141 aattttcaaa atcatagaca aaaaagaatg tctattgtac tatggaatta ttctaaaacg
    28201 ctcccaaaaa ggaggtgcat ataaaattga aacctactat ttatgacatt gcgaaaaaag
    28261 ctaatgtctc aaaatcaact gtctccagag tattaaataa ccagccaaat atctctgata
    28321 aagcaaaagc aagtgtactt caagcaatca aagaattgaa ttatgaaccg agcaaaattg
    28381 caagaggact gtcaggaaat ggttttgacg cgattctagc attatctcat cgtacttctc
    28441 atacgaccta tggcaatcct tttttttcag atgttattca atccatttct gccgtttctg
    28501 aacaaaataa cttcgacttg attctacaaa cggcaaaaac accagaagaa gagctagaaa
    28561 aatgcgcgaa aaagatccaa gaaaaaatga tccgaggaat tattatttta agctctacga
    28621 tggatgaaac acttcttttt gaattggatc aatataatat tcctattgtg gtaatcggaa
    28681 aagtcggaaa cgactacacg aacatctact cagtggacac ggataatttc caggatagtt
    28741 acgatttggt ggaaacactg atcaagaatg gacaccgtca tatcggctgt ctccatgctc
    28801 cgacagaagt ttatgtatcc aatgatcgtc tcaatggtta ccgtcaatgc ttatttgatc
    28861 accacctaga tatccgtaat gaatggatta tagacggcgg ctttcgctta gaagatagca
    28921 tggcagcaat gaatgattta atgaagctac gagaaagacc aactgcgatt ttttctaccg
    28981 atgcattaaa atcattgagt atttacaaag tggcagaaca atctggaaag cagatacctg
    29041 atgatctttc gatcgcagga ttcagtgatc ccttattgtc ctccctattt tcgccacagt
    29101 tgactcggat agacattccg acaaatcagt taggaatcaa agccacagaa cttttattcc
    29161 aactaatcca ccaccaatac cctgaagaaa aaagaatcat tctttcaacc gagattactc
    29221 tcacagattc gatccaacaa caagaaatgt agaacagaat tataaaagaa cagaaacact
    29281 gaggataagt cagttactct gttctttttt caatcactca tccctcgtta ccccctcccg
    29341 gtattttagc gaatttttct tattttccat ctgttttaga tagctgtgga taactataat
    29401 gtttgtgtta aactattttt tccacaggga agaaaaaact atttttaacc acgttgtgta
    29461 taagttttta tagttcgttt ttttaaacac atttaccctt atttcaatcc atgttatttg
    29521 gggatactta tctctaaaac ataaatagaa taacagacat gtctactggt tttgttttat
    29581 tcgaggaatt attcaataat agctagcaaa atattaaaaa taaccgctct atcttcccat
    29641 caatttattt tgcattcaaa aaatgatcta tctttacttt tgttgattga cttctcttgg
    29701 aagatgatcg ttccgatacc ttaattggat acgaaccgat gttgttaaga tcctttccca
    29761 cttttcttct agttagacaa attattttag acaaaccaaa aaagaggttg tgacaataat
    29821 ttgtcacaac ctctttttta aaatatctat tttgtttgat tgttcattgc gtcttctgca
    29881 gccatttgcg cttcaatatc tgaaatactg tagacatttt cgcttgctac accgacttct
    29941 tttggttcca tgtcacgata acgttgcata ccagtaccag ctgggatgat cttacctata
    30001 ataacatttt ctttcaaacc aagaagagga tctttcttac cgcggatcgc agcatccgtc
    30061 aagacacgag ttgtttcttg gaatgatgca gcagataaga aactatttgt ttctaatgat
    30121 gcttttgtga tacctagtaa gacaggtcga gaagttgcag gaacgcctcc tgagactagc
    30181 gtattgtagt tttgatcttt aaagtctgcg atgtctaata atgtacctgg taagatatct
    30241 gtatcacctg gatccattac acgaacttta cgcagcattt gacgaaccat tacttcgata
    30301 tgcttgtcgc cgatttctac cccttgcata cggtaaacac gttgtacttc acgaagcaag
    30361 tagttttcaa cagataatac atcgcgaact tgcaacaatt gttttggatc gattgatcct
    30421 tctgtcaatg gtgcaccacg gtggatcata tcgccttctg ctactttcat acgtgctgta
    30481 taaggaacag tatacgtacg tgtatctgtt tttcctttga ttgttacttc tttggtacgt
    30541 gttgcaggat cttctgagat atcgatgaca tcccctgtta cttctgtgat cactgcttgc
    30601 cctttcggat tacgtgcttc aaagatttct tggacacgag gaagaccttg agtgatatcg
    30661 tctccggcaa ccccacctgt atggaatgta cgcatcgtca actgagtacc aggttcaccg
    30721 attgattgag cggcgatcgt accaactgct tctccgactt caacgtcaga gccagttgca
    30781 aggttgcgtc cgtaacaatg tttgcagaca ccatgttttg tattacatgt gaagacagaa
    30841 cggattgtca ctgtttcgac acctgcatca acgatttgtt ttgcgatgtc ttcggaaatc
    30901 aattggtttc ctgcaatgat caattcattt gtttcaggat gacgtacttc tttacgggtg
    30961 taacgtccca ctaaacgatc ttctaatgat tcgatgattt catttccctc gcggatggct
    31021 tggatttcaa gacctcggtc agtaccgcaa tcttcttcac ggatgattac atcttgggcc
    31081 acgtcaacca gacgacgagt caagtaacct gaatcggcag tcttcaaggc tgtatcggtc
    31141 atccctttac gagccccgtg agttgagata aacatttcca agacggatag tccttcacgg
    31201 aagttcgaaa tgattggcaa ttccatgatt cgaccattag gagcggccat caaaccacgc
    31261 attccggcaa gctgtgtaaa gttggaaatg ttaccacgag ctccagaatc agacatcatg
    31321 aagattggat ttttcgcttc caaaccttcc atcagttttt gttggatgct gtcttttgca
    31381 gcattccaaa cagcaatgac acgttcataa cgttcgtcat ctgtgatcag accacgacgg
    31441 aattgttttg taatagtttc aacttgttta tgggcatttt caatgatttc ttgtttttca
    31501 ttcagtacac tgatgtcagc gatccctact gtgataccgg catgtgtcga atgtttgtac
    31561 cctaagtctt tcatacggtc aagcatctta gaagtttctg ttactttgaa tcgtttgaag
    31621 acttctgcga tgatgtttcc taagtttttc ttcttgaacg gtaatactaa ttcttgctct
    31681 ttgatatgtg caggaatatc agtaccagct tcaacaaagt atttgtccgg tgtttggacg
    31741 gtcaagttga agtctgttgg ttcattcaga taagggaatt caggaggcat gatctcgttg
    31801 aagatgatct taccaactgt tgtgatcatc gtacgttctt tttgccattc agtaaatggt
    31861 ttttcaccta atgagttagg gttcacaccg atacgtgaat gtaaatgaac atatccgttg
    31921 cgccatgcga taacggcttc gttttgatct ctgaagacca ttccttcgcc ttcgcgtcct
    31981 tcttcttcca ttgtcaagta gtagttacct agaaccatat cttgagaagg agtaacaact
    32041 ggtttaccat ctttagggtt caagatgttt tgagcagcta acatcaacat acgtgcttct
    32101 gcttgtgctt cttcattcaa tggaacgtgg acagccattt ggtctccatc gaaatcggca
    32161 ttataagctt cacatacaag tggatgcaaa cggattgcgc gtccttgtac taaaactggt
    32221 tcgaatgctt ggataccaag tcggtgaagc gtaggtgccc ggttcagcaa tactgggtgt
    32281 tccttgatta cgtcttctaa aacatcccat acttcgtctt cttgacgttc gattttacgt
    32341 ttcgcatttt tgatgtttga agctagttcg cgttgaacaa gctcacgcat cacgaatggt
    32401 ttgaataatt caatggccat ttcttttgga agtccacatt ggtacatctt caagaaaggt
    32461 ccaacaacga taacggaacg acctgagtag tcgacacgtt tacctagcaa gttttgacgg
    32521 aaacgacctt gtttcccttt caacatatga gaaagagatt tcaatgggcg gttacctggt
    32581 ccagtaactg gacgtccgcg acgaccgtta tcgatcaatg catctactgc ttcttgcagc
    32641 atacgttttt cattttgaac gatgattcca ggtgcattca agtctaacaa acgtttcaaa
    32701 cggttattac ggttgattac acgacggtaa agatcattca agtcacttgt tgcaaaacgt
    32761 ccaccttcta attgaaccat tgggcgtaaa tctggtggaa taacagggat aacgtccata
    32821 accatccagc ttggttgatt tcctgaagcg cggaatgctt ctaaaatatc caaacggcgg
    32881 attgcacgtg tacgtttttg tccttgtgca gatttcaatt cttctttcaa ttcggctgct
    32941 tctgcatcta gatcaacatt atcaagtaat tgtttaatcg cttctgcacc catagcagct
    33001 tggaattctt gtccatattg ttcacgtttt tcgcgatatt cgcgttctgt caacaattgt
    33061 tttttctcta aattcgtatt tcctggttcg atgactacat atgaagcaaa ataaatgatt
    33121 tcttccaaag cgcgtgggct catgtctaat acaagaccca tacgtgaagg aatcccttta
    33181 aagtaccaga tatgtgaaac aggagctgct aattcaatat gtcccatgcg ttcacggcga
    33241 actttcgaac gagtaacttc cactccgcat cgatcacaaa cgattccttt ataacggata
    33301 cgtttgtatt ttccgcaggc acattcccag tcttttgtag gaccaaaaat ccgctcacag
    33361 aacaaccctt cacgttcagg ttttaaggta cgatagttaa tcgtctcagg tttttttact
    33421 tcaccgtaag accagcttct gattttttcg ggagaagcca aacctatttg catactttcg
    33481 aatttattta catcgatcaa aaggggttcc ctccatttca tttaatggca aaccgcaaga
    33541 cggctgatct tcgaccgcct tgcagctcat agaccggatt agtctaaatt atcttctgcg
    33601 gtttcaaagt tttggatgac atcgtctttt tcatcttcca cttgttcagc agctttcttt
    33661 tctaattctt tggcagtttg ctgttcggca aattttgtca aagcatcaac agtgatcaaa
    33721 tcgtcgtctt catcgtccat gtcgcgaagt tcgatctctg tttcttcgat atccaagaca
    33781 cgcatgtcca gacctagtga ttgcaattct ttcaccaata cgcggaatga ttccggtaca
    33841 cctggttttg gaattggttc acccttgacg attgcttcgt atgttttcac acgtccgact
    33901 acgtcatctg atttgtatgt caagatttct tgtaaagtat aagccgcacc gtaagcttcc
    33961 agtgcccata cttccatttc accaaaacgt tgtccaccaa attgagcttt acctcccaat
    34021 ggttgttgtg taaccaatga gtaaggtccg attgaacgtg catgcaattt gtcatcgacc
    34081 atgtgagcaa gtttgatcat gtacatcaca ccgacagaca cacgtccatc aaatggttca
    34141 cctgtacgtc cgtcgtacag aacagttttc gcatcgctgg ccataccggc ttcacgaact
    34201 gtttcccata cgtcttcatc acttgcacca tcaaatactg gcgttgctac gtggatacct
    34261 aactgacgtg cagccatacc caagtgtaat tccaatactt gcccgatgtt catacgtgaa
    34321 ggcaccccta aaggattcag catgatatcg attggtgttc catcaggtag gaatggcata
    34381 tcttcttccg gcataatacg ggatacaacc cctttatttc cgtgacgacc ggccatttta
    34441 tccccttcat ggattttacg tttttgaacg atataaacac gaactaacat gtttacgcct
    34501 ggtgacaatt catctccagc ttcacgagta aagattttca catcgtgaac gataccgccg
    34561 ccgccatgtg gtacacgtaa tgatgtatcg cggacttcac gagctttttc gccaaagatc
    34621 gcatgcaata gacgttcttc tgcagataat tctgttaccc cttttggcgt gactttccct
    34681 acaagcaaat cgccatcttg gacttctgca ccaatacgga tgatacccat ttcgtctaaa
    34741 tcttttaatg cgtcttcccc gacattaggg atttcgcgtg tgatttcttc aggtcctaat
    34801 tttgtatcgc gggcttctga ttcatattct tcaatatgga tagaagtgta tacgtcatct
    34861 tttaccaaac gacggctcat gatgatcgca tcttcatagt tgtacccttc ccaagtcatg
    34921 aaaccaacta aaacgttttg gcctagagcc atttcgcctt gttccataga tggtccgtct
    34981 gccagagtat cccctttttc gactttctca cccaaatgaa cgattggacg ttggttgtag
    35041 cttgttccgg agtttgaacg acggaatttt gttacatcgt atttatctaa tgcaccgttg
    35101 tcgcggcgta cgcggatttc agaagcatca acgtattcaa cgacaccgtc atgtttacat
    35161 aacaaagcag ctcctgagtc atgcgctgat ttgtattcca taccagtacc aacccatggt
    35221 gcttgaggat tgatcaacgg cactgcttga cgctgcatgt tggcacccat caaggcacgg
    35281 ttggagtcat cgttttccaa gaaaggaata catgctgtcg caacggcaac tacttgttta
    35341 ggtgatacgt ccatgtagtc tactttatca atagatactt ctaagttttc actttgagca
    35401 cgagccataa caacgtcttg agcaaatgtt ccatcttcat tcaatgggct gtttgcttgg
    35461 gctacgatgt aatggtcttc gatatcagct gtcaagtagt cgatttggtc agtaacacga
    35521 cctgtttcac ggtctacacg acgataaggt gtttcgataa atccgaattt atttactttc
    35581 gcataactgg acaaactatt gatcaacccg atgtttgggc cttcaggagt ttcgatcgga
    35641 cacatacggc catagtggga gtagtgaacg tcacgaactt cataaccggc gcggtcacga
    35701 gtcaatccgc caggtcctaa ggctgaaaga cgacgtttgt gtgtcaattc gccaagaggg
    35761 tttgtttgat ccatgaactg tgacaactga gaagaaccaa agaattcttt gatacttgcc
    35821 acaactggac ggatattgat caattgttga ggtgtcaatg tttcagtatc ttggatcgac
    35881 attctttcac gaaccacacg ttccatacgt gctagcccga tacggaattg gttttgtaaa
    35941 agttcaccga ctgaacggat acgacgattt cctaagtggt cgatatcatc gacattgccg
    36001 ataccttcca tcaagttcaa gaaatagctc attgaagcaa tgatgtcggc tggacgaacc
    36061 gtttttacag ctgcttctgg atagccgttt ccgatcacgt ttacttcacg ttcagggtct
    36121 cttggtgaaa atactttgat gacttggaca gtcattggat ctgtgaccac accgtcttct
    36181 gatggatagt aagtcactga atttaggcca ttatcaatga aaggagctag tgtttccatg
    36241 acttggtgag tcagaactgt tcctttttca acgatgatct cgcctgtttc tggatcaact
    36301 aatgtttcag ctaatgtcag attcaataga cgtgttttca aatctaattt tttgtttact
    36361 ttgtaacgac caacgtttgc taagtcgtaa cgttttggat cgaagaaacg agcattcagc
    36421 aagttacgtg agctgtctgc tgtttttggt tcgcctggac gcaaacgttc gtaaacgtct
    36481 ttcaaacctt cttctgttct tgagtcgctt gcgtttttat gcaagtcttt ttcgactgta
    36541 ttgcgtaatg tttcgctgtc gccgaagatt tcaaagatcg tatcatcgga accaaatcct
    36601 aacgcacgaa ctaatacggt taaaggaatc ttacgtgtac ggtcgatacg tacataagag
    36661 atgtcttttg catcagtttc catttctagc caagctccac ggttagggat aacagtagaa
    36721 ccgaatcctt cttttccgtt tttgtcgact tttccatgga aatagacacc tggtgaacgg
    36781 actaactgag aaacgattac tcgctctgcc ccgttgatga tgaatgttcc ttgttctgtc
    36841 attaatggga aatcaccgaa gaatacttct tgtgctttga tttcgccagt ctcgcggttt
    36901 gtcaaacgca atgttacatg taatggtgca gagtagtttg catcatgcgc acgagcttct
    36961 gctactgtat actttggttc tttcaattca taatctacaa attccaaaga tagattgcca
    37021 ttgaagtcat cgattggcaa aatgtcttca aacatttctc taagtccctc atctaagaac
    37081 cattggtaag agtctgtttg aatttcgatc aaatttggta attccaacac ttcactgatt
    37141 cttgcgaaac ttctacgttc gcgatgtttt ccgtatttta ctacgtgtcc agccaagctc
    37201 ttcacccctc taaaatgtca ttcaaaaaga ctacccgatc aattgttaca ataatatttc
    37261 aaatattatt tttaggtaac aacagacatt ttttgcggct tttaggcaaa aaaaaaccaa
    37321 aaatagaaca ttctcttgaa accttacttc gtgagcttct acttttgttt ccttatatta
    37381 aagccgaaac ggacaatatt tcgtttctgc cttttcttca tcagatagtt tttgcaactt
    37441 catatactac acttattttc tataaaagtc aacacttcct ggcgtttctt ctgctttttc
    37501 gcaacatttt cttaatgttt tcaattttat gttttcaatt atctgacaat tcttaattga
    37561 cagacctttt tatctcggtt atactttaga aaattcattt tgtggaggaa cttctatgcg
    37621 aaccaacatc aaccaaatcg caccaacaca actgaataac ttttacttta gctactttag
    37681 ataggtttgt attcatcatg atggatacaa acgttaaacg acagtttgta tctatgatgg
    37741 ctaaagaact ttgtattgca gcaaaaagcc acgtagacaa aatgctaagt ggctgagcag
    37801 tgaaaataca aagtaaaagt atcaagcatt ctactttttc aatttatttt ccgacttttc
    37861 aatccatttg gacattttgt ctgaatggat tttttgtttc ccaaaattaa ggaggaaaaa
    37921 gaaatgaaaa aaaatataat catcggatta ggcgctgccc tgctactagc tttaggaggt
    37981 tgcgcacaaa aagacaattc cgcagaggca tcagatggac aaaaaacaat tggcgtattg
    38041 caacttgtac aacataactc gttagatgct gcctataaag gattcaaaga aggattagca
    38101 gaagaagggt ataaagaagg cgataatcta acaatcgatt atcaaaatgc ccaaaacaat
    38161 caagacaacc tgaaaagtat gagtgagaaa ctcgtcaaag aagatcctga tttgctactt
    38221 ggaatcgcca ctccagcagc acaatcttta ttaaatgaaa caaccactat cccgatgact
    38281 gtcacagcgg tcacagactt ggaacaagcc catttagtca catccaatga aaaacctggc
    38341 ggcaatgtga ctggcacgac agatatggtg ccaatcgaaa aacaaatcgg cttactgtta
    38401 aatatcgtgc cagacgccaa aacaatcggc atcatgtata acaacggtga agcaaactct
    38461 aagatccaag ctgatttggc agaaaaagaa ttgaaaaaag cgggcgtcaa agtcaaagta
    38521 ctgacagcaa attccacaaa tgatgtccaa caagtgacga aaagtctagc taaagatgta
    38581 gatggaatct atattcctac tgataacacg ttcgcaagtg cggcaagtgt tgtcggtgaa
    38641 gtcgcaaaag aaacaaaaac acctgtcgtt gctggcgcag ttgatcaagt caaagacggc
    38701 ggtctagcaa cagtaggaat cgactacgaa agcttgggca aacaaacagg gatcatggca
    38761 gcaaaaatct tagacggcaa gaatccaagt gaacttcctg tcgaaacagc gaatgatttg
    38821 gaactgtatg tcaataaaga catggccaaa gcattaggca tcaatccaga cagcatcaaa
    38881 gaagctgaat aaaacacagg aggattctca tgacaaattt gctctctctt ttcttatcat
    38941 ctgcatcgca aggggtctta tgggccctac ttgcgattgg tgtatacgtc actttccgta
    39001 tcttggacat tgccgacttg actgctgaag gaagctttcc tttaggtgca gggatcgcgg
    39061 cagtaagtat tacaaatggc tatcatccat tgacagcttg tcttctaggc tttttagggg
    39121 gtgcggcagc agggcttgtt tccggactgc ttcacacaaa attgaaaatt cccgcccttc
    39181 ttgcagggat catcaccatg actggtttat attctgtcac atcccgtgtg atgggtgcgc
    39241 cgaacatctc tttattgggt cagccaacga tctttcattg ggtcgagtca ttcggcataa
    39301 caaaagacaa cgctgtactg atcgtcggtc tgctttttgc tttgatcgtt gtatgtttac
    39361 ttgttttgtt cttacgtaca gaaacaggac ttgctattcg tgcaactggc gataatctgg
    39421 caatgagcga agcaaacggg atcaacacag ataatatgaa gatcatcggt tatatgattt
    39481 ctaatggatg cattgctctt tctggctcct tacttgcgca aaacaacggc tttgctgatt
    39541 taaattctgg tattggaacg atcgtaattg gacttgcttc tattatcatc gcagaagttt
    39601 tgttacgtaa ccagccacta tttctccgtc tcttgactgt cgttttaggt gcggtcattt
    39661 atcgttttat tttagcgtta gtcttcgaac tgaatgttga accaagtgat tcgaaacttg
    39721 cttctgcttt cgtgctagtg atctgtcttt ctttcccgca gatccagcaa aaattccatt
    39781 tacctcaaaa aaagaaaggc ggtagtgtca aatgaatgac gtcttaacat tggaaaatct
    39841 ccatcatacc tttgaaaaag gaacgatcaa cgaaaatcat gtcctgaaag gcattaatct
    39901 ttccttagat cccggcgact tcgtgacgat catcggtgga aatggggctg gtaaatctac
    39961 tttgctgaac agcatcgccg gtacattttc tgtcgatcag ggtcaaattt tattgaatgg
    40021 aaaaaatatc acgaaaaaat ctgttgtcga acgttcgaaa tccatcagtc gcgtattcca
    40081 agatcctaaa ctagggacag ccgttcgttt aacggtagaa gaaaatcttg ctcttgctat
    40141 gaaacgagga aaaaaacgcg gcttcttccg tggtgtcaaa ccacaagacc gaacattttt
    40201 caaagaccag ctggttcggc taaatttggg gttggaaaat cgtttatcct cagaaatcgg
    40261 tttgctgtct ggaggacaac gtcaagctat tacgttattg atggccacat tacagcgtcc
    40321 agaactgatc ttattagatg aacacactgc agcgcttgac cctgctactt ccaaaacggt
    40381 gatggaattg acagaaaagc tgatcactga gcagaatctc actgctttta tggtcactca
    40441 tgacatggaa gacgcgatcc gctatgggag tcgactgatc atgctgcatc aaggaaggat
    40501 cgtcgtagat atccagcaag aggaaaaaca gcagctcaca gtgccccaat tattagcgtt
    40561 gttcaaacaa aacagcggca cggcattaaa agacgatcaa gtacttttat cttcataatc
    40621 agaaagagga tgggacaaaa aatgaacgcc caccctcttc ttttttctct ttccttcttt
    40681 cgtttttgct ttatgtatca accgttgttt cttcgaaaac tattttgttc tctccttctt
    40741 cctgatagaa tggatgggaa aggagcttga tgccatgaca acgaaagaca aggtacttca
    40801 attattgaaa aagacaccag attttctttc cggagaaaag ttggcacagc aactggaagt
    40861 ttcccggaca agtatttgga aagccatcaa agaattggaa aaggcaggct atcgttttga
    40921 gcacgggcct acagggtatc gttacctgcc ctctgacgta ctagatgcaa aagaaatcca
    40981 gcaagagcta cggtcgttta ttcctgattt gaaagtacaa acgatgttga cttctgaatc
    41041 tacgatgaaa gatgccaaac tggcagcagc tcaaggagat tctgtttcga agttatttgt
    41101 tgctgataca caagaacaag ctcgtggacg ttttggacgg ccttttttcg ctgaacctgg
    41161 acgaggaatc tacatgagtc tcttgctcca tccagacaaa cggtttgatg aattgcctca
    41221 atatacgatc atcgcagcca gtgcctgtgt gaaagccatt gaatctgtaa ccggtcgttc
    41281 tgcttcgatc aaatgggtca atgatatcta catggatgga aaaaaagtct gtgggatttt
    41341 atctgaagca gtcagtgata tggaaagcgg caggatcagt catatcatca ttgggatcgg
    41401 gcttaatttt tctgttcctc aaaatcattt tccagctgat ctccaagaaa aagccatctc
    41461 tgtctttccc gacggacaag ctagtgtcac aaggaatcag ctaatcagca aaatctggca
    41521 agaattgttc acttatcttt ctcacccaga aaaagcgttg gacttctata aagaaaaatc
    41581 attcgtattg ggaaaaaccg tgtcgttcaa tcaaaaagga acgacttatg tcggtcttgc
    41641 aaaagaaatc ggtgatcatg gcgaactgat cgtccaaaca aatgaacaga agatgagttt
    41701 gtcttctggc gaaatcagtc tcacatctat ccgtacgcaa taattatcag atttcacaaa
    41761 aggacacctg atctcataca gtgtcctttt ttctgaattc tcttcaaaag actctcctta
    41821 ttctatcagc tgacagtttc tctatcctct agaaaaaggt attctaaaaa tatctataaa
    41881 gcatggtaca ctttctttaa atgaatcaat gcaaaaaaca agagagtcat cagtttacac
    41941 gatcaaaaga gatagcaggc cgcttccttt ttcaatctta tagatagacc atgggtaacg
    42001 ataaaaacaa aaaagaactt gcgacttatt ttgccgtaag ttctttttta gctagtgcct
    42061 taatctctta atcccaacaa acgtctcgca tagatcacct gaccagagtg catagcagca
    42121 tcatcaataa tagaaacgag acgcattcct cgtgtgactg gtggtgtcca gttctcgtca
    42181 attacttcat ctagctcgga aggttccagc cttcttaagt aagaaatagc aaaatcagca
    42241 gctcctcgca agtatcctag cagatcttct atttgattag cttggatctg ctttgcttgt
    42301 tccagactat gcttccaatc ttgttcgtta tctgctatcg tcatcggaaa ccggctttcc
    42361 cagtcttgac tatgccaaat tggagaagtt cctgctaaat cagcaatctg gaaatctaat
    42421 tctcgagcgg tatgccaagc cagccaagtc attgatttga tctgcggggc tctatcttcc
    42481 actggaaaac gattggcctc ctcaatagag acgccttcaa acaaacgttc aaaccgatcg
    42541 tatgcccgat ccacactctc gcatagcata tctaaataat ccatttattt tcctcctttt
    42601 tatttatcct acttactttt tcctaattct aggataccta cttatatgtt actacacacc
    42661 cttatttttt acactttaac agtcaccatc atcaatagtt tggagattga aagaaaaaga
    42721 tagtgtcgaa ctatcaattg aacaagaagc aacaatatga acgtttcatt aatattcttt
    42781 aaataaacaa tgatttttca aacgaacagt ttaagactag gagaaaaaga gtataatagg
    42841 aaaatgtttg aaaggaaagg aaggggaaaa atgaaaaaaa gggcaagttt actagtccta
    42901 gttgctttgt tgttcaatat cttttcgtat ggtgtggccg tttcagcgga aacatacatt
    42961 cctaaagacc ctgggaatat ttataatgat ctaactggta actatggctt gttaggaatt
    43021 gctagtcaat tccacgtatt tgctaaaaat aagacaactg tgaatgcaca tacagacgga
    43081 aatatagcaa cacatgaact tgatgcaaaa aataattttg gtacagagct tcatgaaggt
    43141 ttattgaacc aagaaataaa ttatatacaa aaaactgatt ctttcgctaa ttcttcaggc
    43201 atacctacag gtagcacaag aatgaataaa tttgtcgttg gcagtaacgt ggatgtagca
    43261 cttcaagatg gtcatcctac agtcaatgga tccaggcttg atcacttaac tccagatgat
    43321 ttttataaag atcgtgctgg gcatgaatat attgatttcg agcaggaatt tgctaaattg
    43381 aatgtagcag caaatgatct tgcaacgatc actccagcta aaacatatac tgctgcagat
    43441 tttccagaca tgaacaatcg gacaatcgat ttaactgatt tatcagatac cgggttttta
    43501 ttggtaaata tcgatgcaga agtgttaacg atgaatacgc cacttcaaat cattaatcca
    43561 aatgatcaag tagttgtatt taatgtcatc aacagttctt ctgcattgaa cgtacagtca
    43621 ccaatcaaat acaatgatcg ttcaaatcat gaaacagaag atttttcgga tgcgaatatc
    43681 tcttggaatt ttggaaatga gatgactgat ttgacaatca gtgctccttt tcaaggaaca
    43741 atccttgcgc ctaatgctac tatccgcatt actcaaaacc aagacggaac gattatagga
    43801 acaaatgtga ttttagatgc agctaccaat cgttgggatc ctaacgaaat atttatcagc
    43861 gacaatggta cagatacgac agacacaagc gacagtacag atacatctac cacaagtgat
    43921 agctcagatt catca
//
LOCUS       DACDAF010000015        42834 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.015, whole genome shotgun sequence.
ACCESSION   DACDAF010000015 DACDAF010000000
VERSION     DACDAF010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42834
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.015"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(137..514)
                     /locus_tag="IVZ69_000744"
     CDS             complement(137..514)
                     /locus_tag="IVZ69_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182852.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            770..1498
                     /locus_tag="IVZ69_000745"
     CDS             770..1498
                     /locus_tag="IVZ69_000745"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HAP8182853.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            1498..1752
                     /gene="purS"
                     /locus_tag="IVZ69_000746"
     CDS             1498..1752
                     /gene="purS"
                     /locus_tag="IVZ69_000746"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HAP8182854.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            1754..2425
                     /gene="purQ"
                     /locus_tag="IVZ69_000747"
     CDS             1754..2425
                     /gene="purQ"
                     /locus_tag="IVZ69_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HAP8182855.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            2426..4648
                     /gene="purL"
                     /locus_tag="IVZ69_000748"
     CDS             2426..4648
                     /gene="purL"
                     /locus_tag="IVZ69_000748"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HAP8182856.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            4633..6072
                     /locus_tag="IVZ69_000749"
     CDS             4633..6072
                     /locus_tag="IVZ69_000749"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010768528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HAP8182857.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            6104..7147
                     /locus_tag="IVZ69_000750"
     CDS             6104..7147
                     /locus_tag="IVZ69_000750"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HAP8182858.1"
                     /translation="MANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGFGGC
                     FDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEPLYF
                     LDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFAVGI
                     AEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKKTLG
                     EELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSWPIL
                     PIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGKVIA
                     KEKHRVVFIGEER"
     gene            7144..7722
                     /gene="purN"
                     /locus_tag="IVZ69_000751"
     CDS             7144..7722
                     /gene="purN"
                     /locus_tag="IVZ69_000751"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HAP8182859.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            7719..9254
                     /gene="purH"
                     /locus_tag="IVZ69_000752"
     CDS             7719..9254
                     /gene="purH"
                     /locus_tag="IVZ69_000752"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HAP8182860.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            9270..10544
                     /gene="purD"
                     /locus_tag="IVZ69_000753"
     CDS             9270..10544
                     /gene="purD"
                     /locus_tag="IVZ69_000753"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HAP8182861.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            10666..11580
                     /locus_tag="IVZ69_000754"
     CDS             10666..11580
                     /locus_tag="IVZ69_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HAP8182862.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(11713..13278)
                     /locus_tag="IVZ69_000755"
     CDS             complement(11713..13278)
                     /locus_tag="IVZ69_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP8182863.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(13271..14722)
                     /locus_tag="IVZ69_000756"
     CDS             complement(13271..14722)
                     /locus_tag="IVZ69_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP8182864.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(14736..15752)
                     /locus_tag="IVZ69_000757"
     CDS             complement(14736..15752)
                     /locus_tag="IVZ69_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP8182865.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            15972..17060
                     /locus_tag="IVZ69_000758"
     CDS             15972..17060
                     /locus_tag="IVZ69_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP8182866.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            17114..18640
                     /locus_tag="IVZ69_000759"
     CDS             17114..18640
                     /locus_tag="IVZ69_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HAP8182867.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            18642..19847
                     /locus_tag="IVZ69_000760"
     CDS             18642..19847
                     /locus_tag="IVZ69_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8182868.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            20104..21081
                     /gene="guaC"
                     /locus_tag="IVZ69_000761"
     CDS             20104..21081
                     /gene="guaC"
                     /locus_tag="IVZ69_000761"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HAP8182869.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            21345..22769
                     /locus_tag="IVZ69_000762"
     CDS             21345..22769
                     /locus_tag="IVZ69_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HAP8182870.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            23230..24339
                     /gene="pdhA"
                     /locus_tag="IVZ69_000763"
     CDS             23230..24339
                     /gene="pdhA"
                     /locus_tag="IVZ69_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HAP8182871.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            24342..25319
                     /locus_tag="IVZ69_000764"
     CDS             24342..25319
                     /locus_tag="IVZ69_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HAP8182872.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            25344..26987
                     /locus_tag="IVZ69_000765"
     CDS             25344..26987
                     /locus_tag="IVZ69_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005236379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HAP8182873.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            26995..28401
                     /gene="lpdA"
                     /locus_tag="IVZ69_000766"
     CDS             26995..28401
                     /gene="lpdA"
                     /locus_tag="IVZ69_000766"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HAP8182874.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            28563..28838
                     /locus_tag="IVZ69_000767"
     CDS             28563..28838
                     /locus_tag="IVZ69_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HAP8182875.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            28844..29611
                     /locus_tag="IVZ69_000768"
     CDS             28844..29611
                     /locus_tag="IVZ69_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HAP8182876.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            29779..31608
                     /gene="typA"
                     /locus_tag="IVZ69_000769"
     CDS             29779..31608
                     /gene="typA"
                     /locus_tag="IVZ69_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HAP8182877.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            31869..33641
                     /gene="recQ"
                     /locus_tag="IVZ69_000770"
     CDS             31869..33641
                     /gene="recQ"
                     /locus_tag="IVZ69_000770"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HAP8182878.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            33755..34057
                     /locus_tag="IVZ69_000771"
     CDS             33755..34057
                     /locus_tag="IVZ69_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HAP8182879.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            34060..35223
                     /locus_tag="IVZ69_000772"
     CDS             34060..35223
                     /locus_tag="IVZ69_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP8182880.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            35249..38677
                     /locus_tag="IVZ69_000773"
     CDS             35249..38677
                     /locus_tag="IVZ69_000773"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HAP8182881.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            38698..39822
                     /locus_tag="IVZ69_000774"
     CDS             38698..39822
                     /locus_tag="IVZ69_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182882.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            39812..40249
                     /locus_tag="IVZ69_000775"
     CDS             39812..40249
                     /locus_tag="IVZ69_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HAP8182883.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            40233..40571
                     /locus_tag="IVZ69_000776"
     CDS             40233..40571
                     /locus_tag="IVZ69_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HAP8182884.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            40690..41250
                     /gene="rsmD"
                     /locus_tag="IVZ69_000777"
     CDS             40690..41250
                     /gene="rsmD"
                     /locus_tag="IVZ69_000777"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HAP8182885.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            41247..41738
                     /gene="coaD"
                     /locus_tag="IVZ69_000778"
     CDS             41247..41738
                     /gene="coaD"
                     /locus_tag="IVZ69_000778"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HAP8182886.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            41728..42771
                     /locus_tag="IVZ69_000779"
     CDS             41728..42771
                     /locus_tag="IVZ69_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP8182887.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
BASE COUNT        14132 a         7346 c         9563 g        11793 t
ORIGIN      
        1 ataaccaaaa aagaagcaga tccgttagcg gttctgcttc ttttagttta ttatattttc
       61 ttatcaataa taggaacctg attttaaaag cggctacctc tttaccgtgc ctctttacat
      121 acaaaaaata gaggaattaa gcgtaaatgg cttggctatt ataactaaaa tgctggttat
      181 ggagatgttg cagcaagttt tcgagaaaag cgtattccat ctcttgtcca ttgaataaga
      241 tctggatacg ataatgattt ttgaaacgct tctgttcatg aatctgactg attgaaagtt
      301 cgcctttgtg ttctgtctga taaagaaaag tccttttacg gcattcagca cagcgcttgg
      361 ttgctcggcg gatttttcgg aatgtataaa aactagtatc tttattgcat aaataaacgt
      421 ctttgatcga cagcaaatca ttatatagac aggaacgttc ttcagctgtt aattctgata
      481 aaaaaagctg accttgtttt attgcatctt ccatcggcaa gtgcctcctc gaacccatta
      541 tccaaatttt tagttaattc taatatacca tcattaagta taaatgtaaa cgcttgttga
      601 tggtataaga ttttcgtttc tgataaaaca cgaacattaa aagaatctaa tgccttaaat
      661 gtacatattt ttgttgattt ataaaaagat gattgctaaa atttaaagtg aaaaaacgaa
      721 caaaaaacga tgtatttgct tttaatgtaa ataaaaagga gagacgtaca tggagaagaa
      781 agaacttttg tatgaaggaa aagccaaaaa aatatatctt acttctgatg agaacttgat
      841 ttggatagaa tatttagatc aagcaactgc gttgaatggc gcgaggaaag accagataag
      901 tggaaaagga gaattgaata atcaaatcac aagtgcaatt ttccgttatc tgactcaaag
      961 aggaataaaa aatcatttta ttgaacaatt gtctaaaacc gaacaattag caaaaaaagt
     1021 acaaattatc cctctggaag tggttatccg aaatattgca gcaggaagtt tctcaaaacg
     1081 tctaggtgtt cccgaaggta aagaattcat caaaccaatc attgaattct actataagga
     1141 tgaccagttg gatgatccat ttatcaatga agagcatatc tatttcttac aacttgcaaa
     1201 gccggaagaa atcagtgagc tgaaagccca agcgttggct attaatgaaa ttttgaccga
     1261 attatttgct aaggtcggtt tggttttagt agatttcaag ctagaatttg gccggtcgaa
     1321 tggacaaatt ttgcttgcgg atgaagtaac accggatact tgccgattat gggatgaacg
     1381 tacgaatgaa catatggaca aagacgttta ccgcagagat ctaggtgatt tgatcccagt
     1441 ctatcaagaa gtatataacc gtctatcgga actaactgaa gaaaaggagc gagtatgatg
     1501 tatttcgtaa aagtatatgt aacctataaa gattcagtgt tagatcctca aggggaggca
     1561 gtaaaaaaag cagtccatcg tatgggatat gaaacaatcg aagatatccg aataggaaaa
     1621 tactttgaga tacaacttgc tgatgcagaa gaaccaatcg atacagtgat tgaaacgatt
     1681 tgtgacaagc tgcttgcaaa tgtaaatatg gaaacatacc gatatgaaat caaaaaaatg
     1741 gaggaagtat aacatgaaat ttgcggtcat cgtttttcca ggttcaaatt gtgacgcaga
     1801 tatgttatgg gcagttcgcg agatcatggg cgctgatgcc gaatttgtac ggcatgatga
     1861 gtcctcttta gaaggatttg atggggtttt actgccggga ggattctcct atggtgacta
     1921 tttgagatgc ggtgcgattg ctcggttttc tacaatcatg gaagaagtga ttcgttttgc
     1981 tgaagaaggg aaaccagtat tcggtacatg caatggattc cagatattga cagaagcagg
     2041 acttttgcca ggtgtactga gacgaaatga gtctttgcat tttatttgca aaactgtacc
     2101 attgaaagtc aaccccaaga cggcctttac ttcagagtat gaagccgacg aaataatcta
     2161 tcttccagtt gctcatgggg aaggaaatta tttctgtgac gaagaaacac ttcaagaact
     2221 aaaaaaaaat aatcagattg cctttactta taatgacaac atcaacggca gcgtggaaaa
     2281 cattgcaggg attacgaaca aagcagggaa tgtgttagga atgatgcctc atccagaacg
     2341 tgcagtagaa gacttgctag gatcagaaga tgggaaacgg ttctttgctt ccattttaaa
     2401 aaacttcgga aaggtgaccg tatagatgaa aacattgaaa gaaccgacag ctgaagagat
     2461 caagaaaaaa agaatctatg ccgaatgggg attgactgat gaagaatatc gaatgatcga
     2521 agaagatatc ttaggaagaa tgcctaatta tacggaaact ggactgtttt ctgttatgtg
     2581 gagcgaacat tgttcctata aaaattctaa accggttcta cgcaaatttc ctactagtgg
     2641 acctcatgtg ttgcaaggcc ctggagaagg cgcaggcatc gtcgacatcg gtgatggact
     2701 agcagttgtc ttcaaagcag aaagtcacaa tcatccttca gccgtggagc cttatgaagg
     2761 agctgcgaca ggagttggcg gaatcatcag agatattttc agcatggggg ctcgtccaat
     2821 tgcgttgcta gattcattga ggttcggcga attagataat ccaagaacga aatatttact
     2881 agaagaagta gttgcaggta tcggcggata cggcaattgt atcggcatac cgactgtagg
     2941 cggcgaaatt gcatttgatc cttgttatga aggaaaccca ttagtcaatg caatgtgcgt
     3001 aggtttgatt gaacacaaac atatccagaa agggcaagcc gctggcgtcg gtaattcgat
     3061 catgtatgta ggtgcaaaaa caggtcgcga cggtatccac ggagcaactt ttgcctcaga
     3121 agaatttaat caagaagaag aacagcaacg ttctgctgta caagtaggcg atccttttat
     3181 ggaaaagctg ctgcttgaag cgtgtttgga attaatcttg catcattcgg attctctaat
     3241 aggtatacag gatatgggag cagcaggact tgtttcatct agtgcggaaa tggcttcaaa
     3301 agctggctca ggacttatat tgacattaga tgaagtccca caaagagaaa ctgggatgac
     3361 accttatgaa atgatgttat cggaatcaca agaacggatg ttgatttgtg ttaaatcagg
     3421 agaggaagaa aaaatccaag aactatttca gaagtatgat ctagatgcag tcactatcgg
     3481 taaagtaaca gacgacgggc aatatcggct atatcatcaa ggagaagaag tagcaaatct
     3541 gccagtcgat gcattagctg aagatgcacc agtttatcat aaagaaatga aagaaccagc
     3601 tcgaatcgta gaatttcagc agttagctcc ttatcagcca gttatcgaag aacctggaca
     3661 agtattgctt gatctgctgc agcaaccgac gattgcttca aaacgttcaa tctacgaaac
     3721 ttatgattca caagtacaaa ccaatacagt tgtccgtcca ggaagcgatg ctgctgtgat
     3781 gagggttaga gggacgaata aagcgttagc tatgaccaca gactgcaacg cgcgctatct
     3841 gtatttggat ccaaaaatcg gaggacaaat agcagtggca gaagctgcta gaaatattat
     3901 tgctagcggt ggtaagccct tggcgatcac cgactgcctg aactatggtt ctcctgataa
     3961 accagaagtt ttttgggaat tatcgacttc agctgacgga attgctgctg cgtgtgaaac
     4021 gttaggaact cctgttattt caggaaatgt ctctttatat aatgaaacgg atggtcaagc
     4081 aatctatcca acaccaatga ttggtatggt cggattgatt gaggatcata aacatatcac
     4141 tactcaggaa ttcaaaaaat caggggatct aatctatata ttaggtaaga cgtttgcaga
     4201 ttttgatggc agtgaattac aaaagatgca gcttggaaga atcgaaggtg tgatccgaaa
     4261 ctttgatcta tccattgaaa agagaaacca agagttagta ttgacagcca tccaaaacgg
     4321 attgattgaa agtgctcatg actgttcaga aggtggcttg gcaattgcac tggcagaatc
     4381 agctttcaaa catcagctag ggatatctgt acagtttgaa ttgtcctctg ctcaattatt
     4441 tgcagaaact caatcaagat ttgtgttgac agtcgcaccg gaaaataaga cacgattcga
     4501 agaaatgatg ggagatgctg ctgttttagc aggtaaggtg acggatgaag cgataatcga
     4561 aatttcagca actgacggtc agatcaaaat agaaactgca gtagcaagaa agtgctggga
     4621 ggatgcaatc gtatgtctta tgaagtgaag agtttaaatg aagaatgcgg gatcttcggt
     4681 gtttggggtc atccagacgc cgctagtgtg gcatacttcg ggctccatag tcttcagcat
     4741 cgaggacaag aaggtgcagg tatcgtgtcc aatgatcgag gaaagcttaa ggggcatcga
     4801 gatttggggc tgctttctga ggtattcaaa gatcaaagaa aattgcagca gttaacagga
     4861 gaagctgcaa tcggacatgt acgttatgca acagcaggca atggaagtgt ggacaatatt
     4921 cagccttttc tattcaaatt tcatgatcag tcgatcggct tagcgcataa tggtaacttg
     4981 atcaatgctc gttcccttag aaaagagtta gaggaaaatg gggcgatctt ccattctaac
     5041 tccgatacgg agatattgat gcatttgatc cgacgaagtg aagaaacaga ttttttaaat
     5101 aaattaaaaa gtgctttgaa tgaagtcaaa ggtggctttg cctatttatt aatgacagaa
     5161 acggcaatga ttgccgcttt ggacccaaat ggttttcgtc cattagcaat cggacaaatg
     5221 aaaaacggag catacgtgat tgcctcggaa acttgtgcat tagaagttat tggggcacgt
     5281 tttataagag atgtccagcc tggtgagata gtgatcatca atgacgaagg aatccagatt
     5341 gattgcttta cgaaggacac gcagctttct atttgttcga tggaatatat ctattttgcc
     5401 agaccagatt caaacatcgc agggatcaat gtgcatactg cacggaaaaa tatgggacgg
     5461 aatttagcga aagaatcgcc agtaaaagca gatatggtcg ttggcgtacc taattcttct
     5521 ttgtcagccg caagcggtta tgcggaagct agtggaatcc cttatgaaat cggattagta
     5581 aaaaatcaat acattgcccg aacatttatc cagccaacgc ctgagctaag agagcaaggt
     5641 gttcgaatga aattatctgc tgtacgagga gtagtggaag gtaaaaaggt gattatggtc
     5701 gatgattcaa ttgttcgggg tacgacaagc agacggatcg tccatctttt gaaagaagca
     5761 ggggcaaaag aagtccatgt gaggattgct tctcctcctt tgaaatatcc atgtttttac
     5821 gggattgata ttcaaacgcg taaagaactc attgcggcaa atcacacgat tgatgaaatc
     5881 aaagaatgta tcggtgcaga ttctttaggt tttttaagtg aagagggtct gatcgaatcg
     5941 atcggtctgg aaaaagatgc tccgtattca ggattgtgta tggcttattt caacggagat
     6001 tatccgacgc cgttatatga ctatgaagaa aaatatcagg aatcactaaa agaaaaagta
     6061 tcgttctttt aaaagcagac caagaaggga gtatatgaat tcaatggcaa atgcatacgc
     6121 aaaagctggc gtagatgtcg aagctggata tgaagtagta gaacggatca agaagcatgt
     6181 caaaaaaacg gaacgtttag gtatgatggg cgctatagga ggattcggcg gttgttttga
     6241 tttatcggtc tttcaattaa aagagccagt ccttgtctcg gggaccgatg gcgtggggac
     6301 gaaattagca gtggcaatcg aagcagacaa acacgataca atcgggatcg actgcgtagc
     6361 gatgtgtgtc aatgatatct tagcacaagg cgcagagccg ttatatttct tagactactt
     6421 agcaacgggg aaaaatgatc cgttacgttt ggaaaatgta gtaaaaggtg tagcagatgg
     6481 atgtgttcaa ggaaatatgg cgctgattgg cggagaaaca gctgaaatgc ctggtatgta
     6541 ctcaggtaat gattatgatc tagccggatt tgctgtaggg atagctgaaa aatctcaatt
     6601 attgacagga gaaacgatca acccaggaga tgtgttgctt ggaatagcat ctagcgggat
     6661 tcattcaaat gggtactctc ttgttcgcaa aattttcttt gagcagcagc agttttcttt
     6721 atcatcaaaa ctgccagaat tgaaaaaaac acttggcgaa gaattgcttg agccaacgaa
     6781 aatctatgtt tcttccttgc ttccgctgat caaagaaaag aaaataaaag gagctgcaca
     6841 tatcactggt ggagggtttg tagaaaatat cccgcgaatg ttaccagaat ctatggctgc
     6901 acaaatcaaa cttggctcat ggccgattct tccaatattc ggctgtttac aaaaatatgg
     6961 tgaaattcct gagatggaga tgtatgaaat cttcaatatg ggcatcggta tggtcctggc
     7021 agtcgaagaa tcgaaagtaa aagaaatagt acacgaaatt gagcaagctg gcgaaaaagt
     7081 ttatgaaatc gggaaagtga tcgccaaaga aaaacatcgt gtggtgttta taggagaaga
     7141 acgatgagaa tcgctgtttt tgcttctgga aacggaagca actttcaagc gctagccgat
     7201 tatctatcga aaaaaggatt ggaatcttcg attgactggt tgttttgtga tcagcctgaa
     7261 gcatatgttt tgaaacgtgc aactgcgttg agtgtaccgg cagattgttt ttcacctaaa
     7321 gaatttgatt caaaaaaaga gtatgaagaa gcaattttgc ataaattgaa agaaaaaaag
     7381 atcgatttga tcgtattagc tggatatatg cgaatcattg gaccggtatt gctgaaaaat
     7441 tatgataaaa gaatcatcaa tatccatccg tctcttttac ctgccttccc tggtttgcat
     7501 ggcatacgtg atgcctttga agctggagta aaagaaacgg gtgtcacaat tcattatatc
     7561 gaccaaggtg tagatactgg accaatcatc cggcaggaaa aagtgagaat tgaacaggag
     7621 gacacgttcg attctttaga agaaaaaatc catagagtag agcatcgaat ctatccagaa
     7681 gtgattagtg aaattattga aaatggaggc tatctgaaat gacaagagca ttgatcagtg
     7741 tatcagataa aactgggatt gtagcattcg cccaaggttt gattgaacaa ggagtagaaa
     7801 tcatttcaac aggaggaaca aagcatgcgt tggataaagc tgggatcaaa acgctttcga
     7861 tcgaagaagt gacagggttt cctgaaatga tggatggccg tgtcaaaaca cttcatccta
     7921 aaatccatgg tggtctttta ggaagacgcg atctccctag ccatatggag gcaatggaaa
     7981 cggaaaatat ccaaccaatc gactttgttt gtgtcaattt atatcctttc aaagaaacga
     8041 ttatgaaacc agatgtcgaa atagcagaag ctattgaaaa cattgatatc ggtggtccta
     8101 gtatgctccg tagtgcagca aaaaaccatg aatttgtcac ctctgttgtt gatccatctg
     8161 actatgaaga agtactttca gaattacgtc agtatgggca tacttcactt tctttcagac
     8221 aaaaactagc ggcaaaagtc tttcgtcata ctgcggcata tgatgcactg atcgctcaat
     8281 acttaacgga ttgggtggaa gaaaaagaac cggaaaaatt gacacttacg tatgaacgaa
     8341 aacaaacgct tcgttacggt gaaaatagcc atcaagccgc tgccttttat cagtccgctc
     8401 ttctggaaaa atattcgatc gcagcagcaa aacaactcca tgggaaagaa ctttcttata
     8461 ataatatccg agatgcagat gctgcgctac ggatcatgaa ggaatatgac gagccaacgg
     8521 tagtcgcctt gaaacacatg aatccttgtg gtattgggac agcatctacg attttagaag
     8581 cgtgggaagc agcgtatgaa gcagatcctg tttcaatctt tggtgggatc atcgttttga
     8641 atcgagaagt agatctgcca acagcagaac agatgcataa gctgtttcta gaaatcatca
     8701 ttgccccttc ttatacacaa gaagctttgg aattactgca aaaaaagaaa aacatccgat
     8761 tactgacagt agactttgcg caggaagaaa atcaaaatcg agaagaaacg gtctcagtct
     8821 taggtggact tcttgtacaa gatcaagatc tggcaataga aaatgaagaa gagtggaaag
     8881 tcgtgacaaa acgtaagccg actccagcag aagcaaaagc attagcgttt gcttggagag
     8941 ctgtcaaaca tgtgaaatct aatgcgatcg tactggcaaa cgaacgtcag acagtaggaa
     9001 tcggagccgg gcagatgaat cgagtcggtt cagtaaaaat tgcgattgaa caagcgcaag
     9061 agaaaatgga aggtgcagtt ttagctagcg atgcttattt tccaatggat gattcggttg
     9121 aatatgcagc caaacatggt ataaaagcaa tcattcagcc aggaggaagc atcaaagacc
     9181 aagattctat tgatatggcg aataaatacg atctagcaat ggtctttact gatgttcggc
     9241 attttagaca ttagagagga gtcggataaa tgaacatttt ggtgatcggt gcaggtggtc
     9301 gtgaacatgc aataagtaaa aaacttttag ccagtccgaa ggtggatacg gtgtattgtg
     9361 cgccaggaaa tccggggatg acaaaagatg gtatcaattg tgtcgctatc agtgagcgag
     9421 atcattcagc gttaatccat tttgttaaga aagaggctat tgattggagt atcgttggtc
     9481 ctgaagttcc tttgttaaat gggatcgtcg atgattttat ggcggaagga ttgaaaatct
     9541 tcggtccgac aaaagcagca gctctgatcg aaggttcgaa aagttttgct aaacaattaa
     9601 tggatactta tcaaatcccg acagctaaat ccagaagttt tgaatgttac gaaaaagcag
     9661 cagcgtatat caaagaaaat ggtgcgccaa tcgtagtgaa agcggacggc ttagcagctg
     9721 ggaaaggtgt agtcgtggct accacagtga aggaagcgct ggatgcggca gaacaaatgt
     9781 tgaaccagca tcgatttggg gatagtagca aaaaaatcgt cgtagaagag tttttggcag
     9841 gagaagaatt ctcccttttg gcgtttgtcc gtaataccaa ggtgtatccg atggtcattt
     9901 cgcaagatca taagcgggca tttgataacg ataaagggcc aaatacaggc ggaatgggtg
     9961 cttattcacc agtaccgcaa atttcaaaaa agatgattga aaaagctgtg gaagaagttt
    10021 taaaaccagc ggctttggga atgaaagaac taggacgctc tttcacgggt gttttatatg
    10081 cgggtttgat tgctacgaag gaaggaccaa aagtgatcga attcaatgcg cgtttcggtg
    10141 atcctgaaac gcaagtcgtt ctttctcggt tgaagagtga ctttgcgcaa gtaatcgatg
    10201 atttattaga gaatcgtaca gtagagttaa agtggcagca agaaggatac aatgtaggcg
    10261 ttgtggttgc agctgccggt taccccgaag aatatgagac aggaatggtt ctaccagatt
    10321 ttctggaaga agagctttct gtttactatg ctggagtttc ctcaaataac ggcaaactag
    10381 ttggagcagg aggacgtctt tatttagtag aagcatacgg tgagacgatc aaagaagcac
    10441 agaaaaaaat ttacaccgcg ttaatggata aaacgacaga tggaacattt tatcgtacag
    10501 atattggaga aaaagctgcc aatagcgaac tgatcgtgaa gtaaatcagc tgcttccatt
    10561 tataaaaaat acaacaaaca taatcggaag cgccgatttt agtgaagcct tttcataaag
    10621 agtgtggtac acttttgttg tgtatataaa taaggaggag ttcagatgaa aaaaattcaa
    10681 ttaggtactt ctgatcagaa agcagctgca gtgatcttag gctgtatgcg tatcaacaat
    10741 gcggaagatc cagtaaaagt gattgagaca gcttatgaaa acggcattga tttttttgac
    10801 catgcagata tttatggaaa cggtgaatgt gaagaaatct ttgcagatgc tctagcaaaa
    10861 acatcaatca aacgagaaga tctttttatt caaacaaaat gtggaatcgt tccaggtgtg
    10921 atgtttgatt tttctaaaaa acatatcatt gaatctgtag aaaaaagttt gacccgtctg
    10981 aaaatggatt atgtggatgc tttacttctt catcgtccag atacattggt agaaccagag
    11041 gaagtagctg aagcgtttga tgaattggaa cggtcaggaa aagttcgtta ttttggcgtc
    11101 agcaatcaaa aaccaatgca aatcgaattg ctgaaaaaat atgttcgtca accattagta
    11161 gctaatcagc tgcaatttgg cttgaaacat actggaatga tcgatcaagg gattcatgtc
    11221 aatatgacag atgaagcaag tatcgatcat gacggtagtg tacttgatta ttcccgattg
    11281 catgatatga cgatccaagc atggtcacca taccagtatg gattttttga aggtgtattt
    11341 atcgggaacg aaaaattccc tgaattaaac caaacattag aagaactagc agctaaatat
    11401 caaacgacac caactggctt ggcttctgct tggattttac gccatccagc caatatgcaa
    11461 gtgatcgccg gtacgatgaa cgtagggcga atcaaggaaa tcgctcaagc ttcagaaatt
    11521 aatatgtctc gggaagattg gtacgaattg taccgtgctg ctggaaacat tttaccttaa
    11581 agattgtcat aagcaggtca aaagggctat aaattaaaaa gacagaataa cttgaaagct
    11641 gttttcagct tcgagatatt ctgtcttttt ttattgcaaa tggaaagagt atcattgtac
    11701 ggatttcgtt tattagttat ttttgttttt aaggaaaagc tgtgtccgat attcttttgg
    11761 agaaatccct tgttttttct taaataaata actgaaatag ttagggtcat tataaccaat
    11821 ttcaaaagca atatctgaaa tacgatagtc tgattgctgc aataattttt ttgctaattc
    11881 gattctttgt tctgtcagat aatcgatgaa tgtttggtta aacgattgag aaaaaatcgt
    11941 actgaaatga gagggactta atgcaacttg ttgagcgacc caagttaagg acatatctgg
    12001 atcggtaaaa ttttctttga taaaatccaa tgcatggttc aaaattggct gatatttgtt
    12061 ccttgaaggc tgtgagggca gagcagttaa gaaagaaatg aacatataaa ctgtcgaacg
    12121 gtaaagcgag tcgtcggcgc tgattgctaa gcgttgactg gtggatgtgc aatgaaccat
    12181 ttcttgcggg attttctttt ctttcaggca gacatgctgg agtagcttag tcaagacaaa
    12241 taaacgatat aatcgtgttc gagttggtgt gccttgtggt ttcgtcaagt gttcgatgta
    12301 cttagatact tcgtttttcg ataatgaaga caaatcaagt gagaggtcaa agtaaaagac
    12361 agaatcaact ggaagtttcg cttcttgaat caaatcctca tagctgataa tttgttcttt
    12421 aagggaactg gcggtttcaa gtatcatctg cgtgatctca aaagatgcag gtaattcgct
    12481 gattctttct gcgacaggac caatggcgac agaaaaatta tttttttgtc ccttttctaa
    12541 ttcatggacc aacgtttggg ctacctgata actggtctcg atcacatttt cttcaagaga
    12601 atcaactatt aaaaatttga tgaatcgaga ggaaacagca gagaagatca cttgttgatt
    12661 ctccctaaat aaaaacttca aataatcact gagatgagcg taatcttcaa agtctgtact
    12721 gacttggttt gctgctaata atacggtcat ttttttccct gctaaagagc gattgaaaga
    12781 ttcagcaagt ttcaatgttt cactgatcgt aagtgagcct ttgaacaaac cgttcaagaa
    12841 atgatttttt ttcaattcga aaacaagatc agaagaagtg tgcgtttctt tttgctgcaa
    12901 atctaaagca gttactgctt tttctattgc ttgtttcaat tcgctacttt taatcggttt
    12961 aagcagataa tcatctgcct gtacctggat tgctcctttc atataatcga aatcgtcgaa
    13021 tccactaata aatatgagac gagtccaagg aagtagtttc cttgcttctt ttgaaaaagt
    13081 caacccgtcc atgaaaggca tttggatatc agtcagaatg atgtcgggct gtaagtcgat
    13141 aattgaagac agtgccatct caccatctcc agcttcgccg acataagtga ttggataata
    13201 agaaccaagg acagttattt gttcccgcaa gttattgcga atgaggtatt cgtcttcgat
    13261 gataaaaact ttatacatgt ttgtttcctc caattgtttt gggagataga gggatcatca
    13321 gtgtgacagt tgttccttct cggtatttgc tgtcaatcgt gataggtttt tgatcatttc
    13381 cgtaataaag aaggagacgc ttgtttacgt tgtaaagtcc gtagccgata ctgaaatctg
    13441 aatcgatccc tttggctaac tctttacgta tttctgccag tttttctgca gggatgccaa
    13501 tcccgttgtc tataactttg aattggatca tctcatcaat tttgcatgtg gtaatacgaa
    13561 taaatccttt gtgacggacg tacttcgttc catggtatac agcattttca atcaatggct
    13621 gcaagatcat ttttaaaata gaaacaggaa aaagtgtttc tggtatatcg atcttatagt
    13681 caagcatatg gccgtatctt atttttaaga tgactagata atcattgata tggctaattt
    13741 ctttttcaag aggaatccag tcttgtcctt tgcttaaaga cgtacgaaaa aagccggaaa
    13801 gtgcatgggt catagtcaga gcttcttcaa agcagtcttg ttcgatcaaa gaaataatgg
    13861 catccaaact gttataaata aaatggggag taatctgagc ttgcaataca cgaacttcac
    13921 tttgtgctaa atggtattgt ttcaaagcgt tctcccgtaa agactggttt agatcttccg
    13981 ccattttatt catgctagcg gtaagtgttt gtaattccag tgtttccggc agggttaaac
    14041 gaaagccaag gttccctgaa gaaagttgtt ctgacatctc gatcagctga ttgatcggtt
    14101 cttggacctt tctctctaaa aagcgacgat tctttttcgc atagaaaaaa atggtactaa
    14161 gaactccaag ttccactatt gttaatagaa tgagcgagcg gacaagtgtc gtattttttt
    14221 tgcttgctaa gtcgatctcc acacgaacaa aatcttgtaa gatatctgac agcagttgag
    14281 tgacagaatc tacctgattg atgatctctt cattggtatc cataaaatct tttgccaaga
    14341 tattattgat cagctcgttt tgataatctt ccagtgtatc gatcgtacgt agcgatacat
    14401 ctaacgtact aatttcttta agtgtatttg tattattttt gatctctcga atatcattcc
    14461 taagttcttc taggatattt tcctcattga actcatctac ggttacttgg ccagaaatca
    14521 agtcccacat actttccaaa actttttgat caaccttcaa agcaattgca tctgcttttt
    14581 ggatatttgc gatcgtctgt tgataaatca aaagctgttg cgaatataac agtatgctca
    14641 gtagcaaagg gataacagca aatagaagca tggctttgtt tgcttgggca aaaatctgtt
    14701 ttatgcttaa attttttgtc atgatacttc tccagtcaat aatttctggt tgggatgtta
    14761 gctatattct gctgggaaaa gacagtctcg gaaataaaaa tatctttagg taatgttttt
    14821 cctgtttgaa tatttccaaa ataacgagta acggtattgg ctacatacca gccgacatca
    14881 ggtttacact cgactacaca attgacgatt cctgagcgta gcttctcgat catatcttct
    14941 tgtccatcaa tagttacaat gatcaaatct tctccaggtt tgattgatgt ttcttttatc
    15001 gcagctaaag caccgtgagt catttcatca ctatggctgt ataatacatc gatttcggat
    15061 aaatcatttg tttctaaata tcgtttcatc tggtcttttc ctttcatccg aataaaatca
    15121 ccgacaattc ggtgaacaat agtcatcgga ggtttatggt cgatggttcc atcttttttt
    15181 agggttggtt tacgattgat tgattccaaa aatccttcgg agcgtagctt ggtcggtgtg
    15241 gagttctctg aaccagcaag ttctaggatt ctgatttcct gtttctttga atttgtgaag
    15301 tgattgctga caaataaacc cgcccgattt ccttctgctt tgaaactggg gccaatgtgg
    15361 gtgacgaaaa gctcgggatc attcgtttga atatgtctgt cgacaagtat gacagggatc
    15421 cctgctcgct ttgcttcttt taatacagag tcccacccgg attcttgcaa aggagtaaaa
    15481 atgatcatat ccactttata ggcaatgaac gtccgtatat cttggatttg ccgttcctga
    15541 ttcatgtagc catttcggta gagaacttgg taatcttctt tttcaagcgc agtgataatt
    15601 gattcagtat gctttttccg ccagctactc tccgttcctg attgcgaaaa accaacgact
    15661 agtgggtcag gtgcttcctt tgtattaggt gtacacccca tcatttggta agcgattaca
    15721 acaagggcta aaaaaaataa aacacgtttc actttaaatc actccatctg gatttgttag
    15781 tactatctta tcagataaaa gggaaaatca aagtcaaaag gaatcaatcg aaaaaaatcc
    15841 aagaaactta aaaaaatcca agacaaaaaa agtacaccta aaaaatttaa agtaaatccc
    15901 ataaaaaaat caatgttaac gctttcttta ttagctatac tcggtgtatc aattgaaatg
    15961 ggggataaaa aatgaaaaac aaatttagaa agattgttgg gactatcgct attttgaccg
    16021 caagcattct attaagtgcg tgtggcaatt caggatctgc agatgatagt acggggtatg
    16081 taggaatcgc tatgccgacc aaatcagcag aaagatggat cgctgatggg aacaacatgg
    16141 tctcggaatt agaaaaactg ggttataaaa cagatcttca atatggagaa gataaagtag
    16201 aaaatcaagt agcacaaata gaaaatatga ttacaaaagg ggtagataca cttgtgattg
    16261 cttctatcga tggttcggct ttaactgatg tgttagctaa agcaaaagaa gcagatatca
    16321 aggtgatcgc ctatgatcgt ttactgatga attcagaaaa tgtcgattat tacgcgactt
    16381 ttgataattt tggagtaggt gtatcgcaag cagcttatat tgaagagcac ttaggattga
    16441 aagaaggaaa aggaccattc acgattgaat tatttggtgg ctcgcctgac gacaacaacg
    16501 cactaatcaa ttacaacgga gtgatgtctg ttttacaacc atatatggac aacggtcagt
    16561 tggtcgtgcc atctggacag acgagtttca gtcaaatcgc tacgcttcgc tgggatggtt
    16621 ctacggcgca agcaaggatg gataatctgt taagcgcaaa ttatactgac caaacattgg
    16681 atgctgtttt gtcgccatat gatccaataa gtttaggaat catttcgtca ttaaaaggcg
    16741 tggggtatgg gagtgaaagt aaacctttac ctgtgattac tggacaagat gcgacagttg
    16801 ctggcgttaa atcgatcatt gccggggaac aaacacaaac gatctttaaa gacacacgta
    16861 tcttagcaaa aaatacgatt gaaatgatca aagcaatcag tgatggagaa gaggttccgg
    16921 tcaatgatac tgaaacttat gataatgggg tgaaaactgt ccctacgtat ttagcaaata
    16981 cagtatctgt cgataaagat aattatcaag cagagctgat cgacaccgat tattataaag
    17041 aatccgatct gaaaaattaa gaggaaccaa acaaggaact aaagagatct aagtcagaga
    17101 gaggataaga attatggcgg attgtatttt aaaaatggca gatatcacca aaaaattttc
    17161 tggaatccga gcgttagatt gcgtgaatct gatgattgaa cgtggggaaa tccatgcatt
    17221 gtgcggagaa aacggagcgg gaaaatcaac attgatgaat gtcttgagcg gcttgtatcc
    17281 atatggctcc tatgacgggg aaatctttta tgatggaaag ctgtgtcaat ttaaagattt
    17341 gaaagatagt gaagaaaaag gcatcgtcat cattcatcaa gaattagcac taagtcctta
    17401 tctttcaata aaagagaata tttttctcgg aaatgaacaa gcagaaagag gcgtgattga
    17461 ttgggaactg acagaaaaga aaacatatga actgctgaat aaagtcggtt tgtctatcga
    17521 cccgaatctt ctagtatccc agattggcgt agggcaacag caactagttg aaatagctaa
    17581 agcattatca aaatccgtcc gtctgttgat tttggatgag cctaccgctg cattgaatga
    17641 agaagaaagc gcgaatttgc tgagattgat ccgagagttg aaagagcaag gtgtaacctc
    17701 catcattatt tcacataagc tgaatgaaat cgtggatatc gcagatcgaa tcaccatttt
    17761 acgggatgga cagacgattg agacactaga aaatgaaatg atcagcgaag agcatattat
    17821 tcgcggaatg gtgggcagag atttagttga tcgttatcct gaaagaaaac cggatattgg
    17881 agaagtttat tttaaagtag aagactggac ggtctatcac cctcttgatc acgagcgaat
    17941 cataaacgac cacatcaact tgcatttgaa aaaaggagag attgtaggaa tagctggact
    18001 gatgggagcg ggcagaactg aattcgctat gagtctattt ggacattctt atggaagcaa
    18061 gatatccgga cgtatattaa aggaaggggc agagatatca gttaagaccg ttccttcagc
    18121 cattgcaaac ggactcgctt atgtctcgga ggaccgaaaa tctttaggac tgaatctgct
    18181 gatggatatt cgggaaaacg tgacgctgag cagtttggat aaaataagtc aaaaaggagt
    18241 attagataaa gaaaaagaag taactgaggc agaaaatttc cggaaaaaga tgcgtataaa
    18301 aacaaactcc atccatcaaa ttgtcagtag tcttagtggt gggaatcaac aaaaagtcgt
    18361 tttatccaag tggctgatga cacaacccga tattcttttt ttggatgagc caacccgtgg
    18421 gatagatgtt ggggcaaaat atgagatcta cacgattatc gaagaaatgg cagcaaatgg
    18481 caaagctgtc tgtcttatct cttctgaact tcctgaaata ttagggatgt gtgatcgaat
    18541 ctatacgatg aacgaaggac gtattacagg agaagtctcg cgagaagatg cagatcagga
    18601 agtcttgatg aaattaatga cgaaagaaga ggtgggttaa gttggaacag gcaaaaaatc
    18661 ttacggataa aaaagagaaa aaactaaatt tgaaaagtag agcagctgat ctttttggtc
    18721 gctacagcat ggtgatcatt ttagcgggac tacttattgc gtttcaattg atgacggatg
    18781 gtattttctg gcgtccattg aatataacta accttgttct gcaaaatagc catatattag
    18841 tactagctgc agggatgtta ttagttgtgc tcttaggtca tgtggatttg tcggtagggt
    18901 cagtgatggc gtttgttggt gcaattgcgg gcatgatgat ggtcaatcgc caaatgaacc
    18961 cgtggatgac agttatcgca tgtcttgcag taggcgggct gatcggcgca tggcaaggtt
    19021 tttgggtagc ttatgcaggg ataccggcgt ttatcgtgac tttagcagga ttgctgatgt
    19081 ttcgtggact gacacaagtt gttctaggag gccaatctct agcacctttt ccagctgttt
    19141 tccaaaaaat gtctacgggt tatttaccag acttaagcga aggaagcagc cttcacttct
    19201 tgacattgat tttaggaatg atcatcacga tcgtgttagt tgttggtcaa tggcgaacaa
    19261 gaaatcgtcg gaaaaatcat ttatttgaag tggaatctcc aacagctttc ttggtaaagg
    19321 cggtatttac agcagtcgtt gtactaggaa taacttatat ctttgcctct tatcaagggt
    19381 atccgattat tttgatcatt cttggtttga tcgttgcagc atatgggttt ttgacaaata
    19441 aaacagtagc aggtcgacag atttatgcga cgggcggaaa tcgaaaagcg gctgaactat
    19501 cagggatcaa aacaaagcga atcacgttct gggtattcgt caacatggga gtcatggcag
    19561 ctttagctgg attagtttta gctgctcgat tgaatgcggc aacacctcaa gcaggtacat
    19621 cgatggaact ggatgcaatg gcggcagtat attttggtgg tgcttcgact tccggcggca
    19681 ttggaacaat catgggtgcg attgtcggtg gcttggtcat gggtgtattg aacaatggca
    19741 tgtcgatttt aggcgtcggg gtagactggc agcaggcaat caaaggattg atcttgcttt
    19801 tagccgttgt gctagacttg tataataaga aaaaacgaac aacgtaggag aacgccggtt
    19861 attcagaaaa aagactgtga caagacattt gtcacagtct ttttttcgct aaaagcgaac
    19921 attcattgtt tcgtttgtat agactaaaaa taatatatgt ttttttacca ttcgtataaa
    19981 ttctcttttt gctcttgatt tttttgctta attgagttaa attacatagg gcgctaaaaa
    20041 aagccttgat taaattaata atgttcgtgt tttgctggat gtgaacatca ggaggataat
    20101 gtaatgaaag tatttgatta cgaagatatt caattaattc ctaataaatg tatcgtaaat
    20161 agccgttctg aatgtgatac aacggtcaca ttaggtaaac atacattcaa aatgccagta
    20221 gtgcctgcca acatgcagac gattattgat gaaacaatcg cagaattctt agcggaaaat
    20281 ggttatttct atatcatgca tcggtttgat gaagcagctc gaattccgtt tatcaaaaaa
    20341 atgaaaaagc gtggattgat tacctcgatc agtgttggcg tcaagaaaga ggaatattcc
    20401 tttatagaga agttggcaga agaatcgcta aatcctgatt atatcactat cgacatcgcg
    20461 catggacatg ctaactcagt tattgatatg attcagcata ttaaaaaata tttgcctgaa
    20521 acttttgtga ttgccggtaa tgttggtaca ccggaagccg tccgtgaatt ggaaaatgcg
    20581 ggcgcagatg caacaaaagt cgggattggt ccaggaaaag tatgtattac aaaaatcaag
    20641 acaggctttg ggactggagg ctggcaactg gcagctctta gatggtgtgc gaaagcagct
    20701 cgcaagccga tcatcgctga cggtgggatc agaacacatg gcgatattgc aaaatctgtc
    20761 cgttttggtg cgacaatggt catgattggt tcattgtttg ccggtcacga ggaatctcct
    20821 ggcgaaacaa aagtcgaaaa tggaatcgtg tataaagaat actttggttc tgcttcagaa
    20881 ttccaaaaag gcgaaaaacg aaatgttgaa ggaaagaaaa tctggatcca acacaaagga
    20941 tctttgaaag atacactagt ggaaatgcaa caagaccttc aatcatctat ttcttatgct
    21001 ggaggaagag atctggaagc cattcgaaaa gttgactatg tcatcgtgaa aaattcgatt
    21061 tttaatggag acacaatcta aaaaataaat aaaatattag gatgttgtga aaaagttgtc
    21121 ctgcattaag taataagaac agccaaacaa aaatagttct ttatatgttt tgtttggctg
    21181 gaattattat cgcagataca agcttttgaa catcattatt cagaataagg gactgtgata
    21241 agatttttgt cacagtccct tatgttttgc aaaaaaagtt tttctttttt ctcgtaaatt
    21301 cggtaaaatc aaaagaaaaa atagacaata gaaaagagaa gcttatgtgg gaaaaagtag
    21361 agaaaaaaca aggaccgatt tatcgtcaaa ttatggaaca gattatgaga gaaatcgaaa
    21421 acggaaggat caatcctgga agtcaacttg aatcagaacg aaaactaggg caactttttg
    21481 gtgtgaatcg ttccaccgtt gtccatgcat tggaagagct tagggagctt ggggtactaa
    21541 cgagcaaacg tggcagcgga tggtttgtta atcagactga atgggggaaa ttcgctgttc
    21601 caagaatcga ttggcggcaa atgatctctc ctcgttatga gcagacggac tggtatgagc
    21661 aaaaaataag agaagcaaag cagatccaaa aaacatcgtt tcttgattta tacgctagcg
    21721 agatgccaga tgagcttttg ccgaattttg agtttccttc ttattctctt gaagaaatct
    21781 tagcggaaga aaaagaaatg gatcttttag gctatactcc gttacgtaac aaaatcaaac
    21841 ggtatttgga aagtaaattt gaattggcat tttcccccaa ccagcttctt gtgactggtg
    21901 gcggtcagca agcaatcttt ttgattttac aaacgattct ttcagctgga gaggggatag
    21961 ctgtagagtc accttctttt ttttaccgat tacctctttt caaagcttca ggaacgcgtt
    22021 tatttgggat accgatggat gaagaaggga tcgacttaga aaaactgaaa gaatcgatcc
    22081 ataaaaataa attgaaagca gtgcttatca acccgaattt tcaaaaccct acaggaaaag
    22141 tgatgagtca aaaacgacga gaaaagctag tagaattgtg tcgacagtat cggcttccaa
    22201 ttattgaaga cgatgtattt acggatcttt catttctaaa ccaagaagaa gtccttccta
    22261 tacgaacgat tgatccggat aatgtgttat acgtcggttc gttatctagg gttttaggaa
    22321 aaacaacgaa aatcggttgg gtgataggac ctgagacttt tatctcgcaa ctagctcaag
    22381 cgcaagaaat gatggagttt tcgatgaata tccttacaca aatcacagtg gctaatgtat
    22441 ttaatgaagc aattgatttg aaaatgcaag atgtaagaaa aaagttgaaa gaaaaaagcc
    22501 gactgataag cgcttgggga gattcacaat cgtttttcaa gcttcattca attttaggtg
    22561 gttactatgc ctggattact tgggatggga aaaaactaga ccccgaacta gcagaaaaag
    22621 tagtagatat gggtcttgga attgcaccaa gtctactttt tgggcaagat ataaatggaa
    22681 tcagaatcaa ttacagtagg ctggatgaaa accaaatacc gttgttttat tcaaagatga
    22741 aaattctaga aaagtggtta acagaataat ttcacaaagt aaatagatta aagaatataa
    22801 cagcttggat ttaaatttca agctgtttct tttttttcgg aaaaagaata cgatataaag
    22861 aaactaagaa aaaaccatta tttgtacgtc cgttcacgat gtgtaaataa aataaatgtt
    22921 tgcaacaaaa ctgtataaca ccaacgtttt taaatagaaa cagatggttg taagtttgat
    22981 tagaaaatag aaaaaatgca gatgaaatat aaaacgcttt ccttattgtg attttattca
    23041 ctaatgctgt taatatgcgg attggcataa tttcctttca tcgtgaaaat ttgtgctttt
    23101 agcttgtatt tctcataaat ccatgataat ttattaatga agacggttaa atagtgatac
    23161 agttttattc actgtttcaa tcgcagaatg aagagatttt cttatagatg agagaggaat
    23221 gtgtgacaaa tggcaaacaa aaaagcaccg atcgacttcc aagcactgct agatgaagtc
    23281 aatgcagatt tcccagtata tcaagcactt gatcaagatg gaaacgtagt taacaaagat
    23341 ttagtacctg atttatccga tgatgaactc gttgaattaa tgactcatat ggtatggtct
    23401 cgtgtattag accaacgttc aacagcgctg aaccgccaag gacgcctagg cttttttgca
    23461 ccaactgctg gacaagaggc aagtcagctg gctagtgctt acgcatttga taaagaagat
    23521 gttcttcttc caggttatcg ggatgtacct caactagtaa aacatggttt acctttatct
    23581 caagcttttt tatggtctcg aggacatgct gcaggtaatt cttatccgga agaattgaaa
    23641 gctctaccac cacaaattat catcggtgca caatatgtac aagcagccgg tgttgcatta
    23701 ggtttgaaga aacgaaacaa gaaaaatgtc gtcttcactt atactggtga tggcggttca
    23761 tcacaaggtg atttttacga agcaatcaat ttcgctggcg cttaccatgc aaatgccgta
    23821 ttttatatcc aaaacaacgg gtatgcgatc tctacacctc gtgaaaaaca aactgcagca
    23881 aaaacacttg cacaaaaagc tgtcgcagct gggattcctg gtattcaagt cgatggaatg
    23941 gatccgcttg cagtatatac tgtatctaaa atggcacggg aatgggcgat cagtggaaat
    24001 ggaccagtcc taatcgaaac actgacttat cgttatggac cacatacact atctggtgac
    24061 gatccaaccc gctaccgtac aaaagacaca gatgacgatt ggcagaaaaa agatccattg
    24121 atccgcttcc gtaaatattt gacggaaaaa ggactttggt ctgaagaaaa agaagaacaa
    24181 gtcatcgaag caactaaaga agaaatcaaa gcagctattg ctgaagccga caaagtacca
    24241 aaacaaaagg tttcagattt cttgaaaaac atgttcgaag tatctccaca atcaatcaaa
    24301 gaacaaattg caatttatga agcgaaggag tcgaaataat catggcacaa aaaacaatga
    24361 tccaagcaat cacagatgcc ttagcacttg aactagaaaa tgacgagaat gtcgttgttt
    24421 ttggtgaaga tgttgggaaa aacggaggag ttttccgggc aactgaagga ttgcaggaaa
    24481 agttcggaga agaccgagta ttcgatactc ctttagctga atctggaatc gcaggattga
    24541 gtttcggtct tgcgttagaa ggatttcgtc cagttcctga aatccaattc tttggtttta
    24601 ttttcgaagc aatggacgaa gtagtagctc aaatggctcg tacaagatat cgaatgagcg
    24661 gcactagaaa tctacccatc acaattcgtt cgccatttgg tggcggtgtt catacaccag
    24721 aattgcattc ggataattta gaaggtttga tcgctcagtc tcctggtatt cgagtagtga
    24781 ttccttccaa cccttatgat gcaaaaggac tattgatttc ttctattaga agtaacgatc
    24841 cggttgtttt cctagaacac atgaaactat atcgctcatt ccgagaagaa gtgccggatg
    24901 aagcttacga agttcctttg gataaagcag cagttactcg tgagggaaca gatgtatcta
    24961 ttatcacata cggagcaatg gtgcgtgaag caatcaaagc agcagacaat cttgcaaaag
    25021 aaaatatatc tgttgaaatc attgatcttc gtacagttgc gccattagat gtagaaacga
    25081 tcattcaatc cgtggaaaaa actggtcgcg tagttgttgt ccaagaagca caacgacaag
    25141 cgggcgttgc cgcgcaagta gtttctgaga tctcagaacg cgctatcctt tcattagaag
    25201 ccccaatcgg acgagtttct gcacctgata cagtcttccc atttggacaa gcagaaaatg
    25261 tctggttgcc aaatgcaaaa gatatcgaag acaaagtaaa agaaatcgcg gaattttaag
    25321 aaaagaaggg acgaaacaaa gtcatggctt atcaatttaa attgccggat atcggtgaag
    25381 gaatcgcaga aggtgaaatc gtcaaatggt tcgtcaaacc aggagatacg atcaatgaag
    25441 atgatacatt actagaagtt caaaatgaca aatcagtaga agaaatcccg tcacctgtta
    25501 caggaacggt taaaaatgtg attgttccag aaggtaccgt agcaaatgtt ggggatgtat
    25561 tagtagaaat cgatgcacca ggacacgaag acaatgaagg ggacagtggt gtagccgcag
    25621 aatcccaaac tccagctaaa ccggctgctg aacccactgt tgatacagaa tcagctggat
    25681 cgtcaagcga aggagtcttc caatttaagt taccggatat cggtgaagga atcgcagaag
    25741 gtgaaatcgt caaatggttc gtcaaaccag gagatacgat caatgaagat gatacattac
    25801 tagaagttca aaatgacaaa tcagtagaag aaattccgtc acctgtcaca gggacagtta
    25861 aaaacgtgat tgttccagaa ggcactgtag caaatgttgg ggatgtatta gtagaaatcg
    25921 atgctcctgg acacaatagt gcaccgtcaa ctagtgcgcc atcagctgaa gcaccaaaag
    25981 aaaaagtgga aacatcaggt tcagcaagtg tcgttgaagc tgccgatcca aataaacgtg
    26041 tattggctat gccatctgtt cgtcaatttg cccgtgaaaa agatgtagat atctcacaag
    26101 taactgcaac tggaaaaggt ggcagagtaa caaaagagga catcgaaaac ttcttggcag
    26161 gtggtccaag cagtgcacca gcgaaatcag aagcgccaga agcggcagca ccgaaagaag
    26221 cagctcctgc agcagaaagc aaaccagctg caccagcaaa accattcaag tccaacttag
    26281 gagacttgga agaacgtgta gcaatgacgc caacacgtaa agctatcgct aaagcaatgg
    26341 tcaacagtaa gcatacagct ccacacgtga cattgcatga tgaagtagaa gtgtctaaac
    26401 tatgggataa tcggaaacga tttaaagaag ttgctgctgc aaatggtacg aaacttactt
    26461 tcttgccata tgtcgtgaaa gctttaacag cgactgttaa gaaataccca gtattgaatg
    26521 catctatcga cgatgcaaac caagaaatcg tttataaaca ttactacaat atcggtattg
    26581 caactgatac ggatcacgga ctatatgtac caaatgtgaa agatgcagac cgcaaaggaa
    26641 tgtttgctat tgcagacgaa atcaatgaga aagcaaaatt agctcatgac ggcaaactat
    26701 ctgcagaaga tatgcgcaat ggaacaatta cgatcagcaa tatcggatct gtaggtggcg
    26761 gttggtttac accagtcatc aactatccag aagtagctat tttaggtgta ggaacgattg
    26821 cacaacaacc aatcgtaaat gctgaaggcg aaatcgttgt cggtcgtgtg atgaaactgt
    26881 cattaagttt cgatcaccgt atcgtagatg gagcaactgc gcaacaagca atgaataata
    26941 tcaaacgtct tttagctgat ccagagctat taatgatgga aggatgataa acaaatggta
    27001 gttggagatt ttgctgtaga attagataca gttgtaattg gtgcgggacc tggtggctat
    27061 gtagctgcca tccgcgctgc tgaaatggga caaaaagtag caatcattga aagagagtat
    27121 attggcggtg tttgtttgaa tgtcggctgt attccttcaa aagcactgat agctgcagga
    27181 caccattatc aagagtcact agattctgaa atgtttggag taactagtga aaacgtcaaa
    27241 ctagattttg caaaaacaca agaatggaaa gaaaacaaag ttgtccatac gttgacttct
    27301 ggtgttggtt tcctattaaa aaaacataag gttgaaacaa tcgaaggaga agcgttcttc
    27361 gtagatgatc acacactacg cgtcattcat ccagattcag ctcaaactta ttcgttcaat
    27421 aacgcaatca tcgcaacagg ttcccgtcca atcgagattc caggatttaa attcggagga
    27481 cgtgtgttag attctactgg cggattagca ttgaaagaag tacctaagaa atttgtgatc
    27541 atcggtggcg gtgtgattgg tgccgaattg ggcggagcgt acgcaaactt aggagcagaa
    27601 gtaacgattc ttgaaggctc accacaaatt ttaccaactt acgaaaaaga tctagtaaaa
    27661 ttagtagaag atgatttcaa gaaaaaaggc gtaacagtcg taacgaatgc aatggcgaaa
    27721 gaagcagtcg ataacggtga cagcgtgaca gtgaaatatg cagtggacgg gaaagaagaa
    27781 tccgttactg ctgattatgt gatggtcact gtaggtcgtc gtccgaatac agatgatatg
    27841 ggcttagaac aagcgggtgt cgaagtagga gaacgaggat tgatcacggt ggataaacaa
    27901 ggacgtacga acgtacctaa catctatgcc atcggtgata tcgttccagg ggcggcatta
    27961 gcacacaaag ccagttatga agcaaaaatc gctgctgaag caatctctgg caaaaaagta
    28021 gctgtagatt ataaagcaat gccggcagta gccttcactg atcctgaatt ggcttctgta
    28081 ggtatgacga tcaaagaagc aaaagatgct ggtatcgaag caaaagcata taaattccca
    28141 ttttcaggga acggtcgggc attatcgctt ggtaaaacag aaggattcat ccgtctagtt
    28201 acgacgatcg aagataacgt gcttattggc gcgcaaatcg gtggagtcgg cgcaagtgat
    28261 atggtctctg aattagcttt agcaatcgaa tcaggaatga atgctgaaga tatcgccttg
    28321 acgattcatc ctcatccatc tcttggcgaa atcgtcatgg atgcttcgga attagcatta
    28381 ggtttaccaa tccatatttg atttgaataa tacaggcgaa acgcaactga aaaatcagtt
    28441 gcgttttgtt ttttagaatt atcaataata ttattatgta aacttaaaaa tatgacaact
    28501 tcttggttta ttaccacttc ctatgctaca ctgaagagga atatgaaata ggagagttga
    28561 agatgcaaga atatcagtat ccacttgatt tagattggac aacagacgaa atggtcattg
    28621 taatgaagat gtgggaagat ctggaacgtg cgaatgaaaa agggataaac aatgaagctt
    28681 ttttgaagac ttatcagcag tttaaaactg ttgtcaaatc cattggtgag gaaaaacgat
    28741 tgggacggga atttgaaaaa gcttccggtt attctttata tcgtacagtg cagcaagcaa
    28801 aaaaaaatcc aaacaaaact ttgagaatga acgggtgaga taaatggaac agatgattga
    28861 tcatatcaag tcctggcttg aagaagctgg tgagaaaatc aaatcttctc aacaaacatt
    28921 aacaatctcg caaaaatcaa atcgaacgga tctagtaaca aatgtcgatc gaaacatcca
    28981 gaattttcta atcgaaaaaa tccattcctt tgatccagag gcgaaaatat tggcagaaga
    29041 agaagggtgt aatcaattat cggatctcga tggaagagtc tttatcatcg atcctattga
    29101 tggcaccttg aattttgtga ttgaagggga aaatttttgt attatgctcg ctgtttatga
    29161 atccggcgtt ggaaagcttg gtttcattta tgacgtgatg agaaatgaac ttttttgggg
    29221 tggaaaagga ataggcgtgt ataaaaatga tgagccattg cctagaccag caaataaatc
    29281 cttatcggaa ggcttacttg gtgtgaatag ttatcttttc ggtcataata aatatggaat
    29341 ccgagaaatt gcggaaagca gcatggggac acgtatgtac ggatgcgctg gtcttgaact
    29401 agtggcaatc ttgaaaggaa accacattgc ttatatttca aaccttagcc cttgggatta
    29461 tgcagcggga aatgtcttat tggaagagtt tggtatggta acaagcggtc tttttggtac
    29521 tcctttgaca tttgaaaaaa gggaatacta tttagcaggg acttcttgtg catatgcaga
    29581 aatcgcagac cttttgaaaa aagaaggctg aaaaaaaggt agaaatcatt cacaaaaatg
    29641 ataaaaacga gcaaaagatt aattttctcg aaaaaatgaa aacattttac tatatttcat
    29701 gaaaaaagtc tgctataatt agcagtcgag taaaatttgc cctgtcataa agaaccaata
    29761 aaaaaggagt tagttacatt gaattataga aacgatatcc gtaacgtcgc aattattgcc
    29821 cacgttgacc acggaaaaac aacattagtt gatgaactat taaaacaatc agatacatta
    29881 gacgcacata cgcaattgca agaacgtgcg atggactcaa atgcgctaga aaaagaacgt
    29941 ggtatcacga ttttagccaa aaacacagct gtagactata aaggtattcg cgtaaacatc
    30001 atggatactc caggacacgc ggacttcggt ggcgaagtag aacggatcat gaaaatggtt
    30061 gacggcgttg tgttggtcgt agatgcgtat gaaggaacaa tgcctcaaac acgttttgta
    30121 ttgaaaaaag cactggaaca acatatcaca ccaatcgttg tcgtaaacaa gattgacaaa
    30181 ccttctgctc gtcctgagca tgtcgtagat gaagttcttg aactattcat cgaattagga
    30241 gcagatgatg atcagttaga ctttcctgtg atttatgcat ctgcactaaa tggtacgtca
    30301 agcttgtcag atgatccagc agatcaagaa ccaaccatgg cacctatttt tgatacaatt
    30361 attgaaaaaa tccctgctcc tgtcgataac agcgacgaac cattacaatt ccaagtttca
    30421 ttacttgact acaacgatta tgtaggtcgt atcggaatcg gacgtgtatt tagaggaaca
    30481 atcaaagtag gagaccaagt agcattaatt aaattagacg gaacagttaa gaaattccgt
    30541 gtaacgaaat tatttggttt ctttggacta aaacgtctag agattcaaga agcaaaagct
    30601 ggagacttga ttgctgtctc aggtatggaa gatatctttg tcggtgaaac agttactcct
    30661 gtggatcatc aagatgcgtt acctatcctt cacattgacg aaccaacatt gcaaatgact
    30721 ttcttagtta ataattcacc atttgccggt cgagaaggta aattcgtaac cgctcgtaag
    30781 attgaagaac gtttgatggc agaacttcaa acagatgtat ccttacgagt tgaaccaaca
    30841 aactctccag atgcatggac agtttctggt cgtggagaat tgcatttgtc tatcttgatt
    30901 gaaaacatgc gccgtgaggg atacgaattg caagtatctc gtccagaagt tattgaaaaa
    30961 gaaatcgacg gtgtaaaatg cgaaccgttt gaacgcgtgc aaatcgatac accagaagaa
    31021 tatatgggta gtgttatcga gtccttgagc ttacgtaaag gtgaaatgca agatatggtc
    31081 catacaggaa acggacaaat ccgtttgaca ttcttaacac ctgcccgcgg tttgattggt
    31141 tattcaactg aattcctttc aatgacacgt ggttacggaa tcatgaacca tacttttgac
    31201 caatatctgc caatgcttcc tggtcaaatt ggcggacgtc accaaggggc gcttgtttcg
    31261 atcgatacag gaaaagcaac gacttattct atcatgagta tcgaagaacg cggtacagtc
    31321 ttcgtagaac caggtacaga agtatatgaa ggaatgatta tcggggaaaa cagccgtgat
    31381 aatgatttga ctgtcaacat cacgaaagca aaacaaatga caaacgtacg gtctgctact
    31441 aaagaccaaa catctgtcat caaaaaacca aaacaattga cgttggaaga atctttggaa
    31501 ttcttgaatg atgatgaata ttgcgaagta acaccagaaa gcattcgctt gagaaaacaa
    31561 attttagaga aaaatgctcg tgaaaaagca tctaaaaaga aaaaataatc tgtaaaagga
    31621 tgaagagaga aaccagcttg ttataaaaaa tagctggttt ctttttttgt ccaactcttt
    31681 tctgtggaga agtcatcttt gtcaatggac ataaattcag aaaatacgcc gaaagacgtt
    31741 taaaagactt ttaaaaaact tatttctaga gagtttttgt ttcataataa gataatgttt
    31801 cacgaaagga gatcaacttg tccttcgaag aaaatcgaag taaaatggca agagaaagga
    31861 gcgggaagat gaacgactta ttaaaacaat actttggcta tgatgagttt agacctggtc
    31921 aaaaagaaat tatccagaaa gtcattgatc aggaaaatgt attaggaatc atgcctaccg
    31981 gaagtgggaa atcaatctgt taccagcttc cagctttact attagatggg cttactgtgg
    32041 ttgtgtcccc tttaatctct ttgatgaagg atcaggtgga cgcggcgaat caattaggta
    32101 tacccgccac ttttatcaat agctcgttag atggttacga aacagctaga cgcttccaag
    32161 aaatcgatag acagcagtac cgtttacttt atatcgctcc tgaacgtttt atcatgccgg
    32221 attttatcca agcaatgaag cgatggaacg tccgtatgat cgctattgac gaggcacatt
    32281 gtatctctca gtgggggcat gatttccgcc caagttattt acagatggcg aaccagctag
    32341 atcaactgcc aaatcgtcct gtaattgttg ctttgacagc tacagcgact gtgcaagtag
    32401 ctgctgacat aaaaagactt ttaaaaattc cagaaaacaa ccatattcag actggttttg
    32461 aacgagaaaa tctacgattt caagtaatta aagatcaaaa aaaagaacaa tatctaatcg
    32521 aatatttaaa gatcaacaaa aatcaatctg gtatcattta tgcagcaacg agaaaagaag
    32581 tagaccgtct ctatcatttg cttaaaaaat tcgatttttc cgtgggtaga tatcatggtg
    32641 gtctaaatga gaatgagcga acagaaatgc aagaagcctt tttatacgat cgcttgcagc
    32701 tgattgtagc gacaaatgca tttggtatgg gtataaataa aagcaatgtc cgttttgtta
    32761 tccattatca aattcctggc tctctagaag catactatca ggaagctggt cgggcgggaa
    32821 gagatggtct ttccagtgaa gccatcctgc ttttctctcc tcaagatatc caagtccaaa
    32881 agttttttat ccagcagtcc caaagagaag aagggcaaaa gcaaaaagaa tatgaaaaat
    32941 taaaagcgat gacagaatac gtgtatattg agtcctgtct tcagcaatac atcctaaact
    33001 attttggcga gacaagcagt ccgtgcaacc gttgtggtaa ctgtttagat gacagagaaa
    33061 tagtagaagt aacgacagaa gcacagatgg ttctttcttg cttaaaacgt atgggtgaga
    33121 actatggtaa acaaatgctg atgaaagtct tagcaggatc gaaagaacaa aagctgcaag
    33181 ctttaggttt tggacattta tctacctatg gactgatgaa aaaccaatcg caaaaagaaa
    33241 cgatgcagtt aattgaatat ttgatatcga atggctatct tctgaccatc aatggtgagt
    33301 atcctgtttt gaaagtaaca gaaagaggga tacaagtatt gaaaggacaa gaatctgttt
    33361 atcgaaagga acccaagaaa gtccagcagc tatcggatga agaaaccgat acactatttg
    33421 aagtgctgcg ggaactgcga acggatctag catcagaagc aggcgttccc ccgtatgtcg
    33481 tattttcaga ttccacattg aaagaaatga gccgaatacg tccatcaagc agattggaga
    33541 tgcttcagat aaaaggagtt ggccaaagca agcttgataa atatggcgaa gcctttttat
    33601 ctcggataaa aaatgcggac tctaacgttc tggataagta gaaagaacga atacgtaaaa
    33661 atgaataaaa acaactggtt aaatctgttt tttttgctcc ttatgaaaat caaatatgtt
    33721 ataattaagg aattagaatg ggaggtaagc acagatggat tctttgtcga aaaaacttgc
    33781 gatccaagta ttaaatgatg aagcagaacg gatcaaacga ttaatccgaa atcaaaacaa
    33841 cagtctctgt atctcacaat gcaaagcctt cgaagaagtg gtagatacac agatgtacgg
    33901 cttttcccgg caagtcggtt ttgctgtccg tataggagta atcggaaaga acgagggcca
    33961 gctgatgtta agtgagctag aacgagaatt gaatcagtta tatagtgagg tttaccaaga
    34021 aatttatgat aaaaaagaag ttggcaagga ggaatagact tgcctaagaa agtgaaaaaa
    34081 aggcatctat tagactatag catcttgatt ccctatttaa ttttatgtgt attgggattg
    34141 atcatggtat atagttctac gtcgtatcta ttattagaaa acggacaaaa tccgtccgca
    34201 tcagtcatta accagagtat tttttgggtg cttagcttga ttgctatcgc actactttat
    34261 aaaatgaaaa cagatgtttt gaaaaaccag cgtttgatca tggcagccat cgcagttttg
    34321 acgattttgc tgctgattgt tgtgtttttt ggtaaggaga tcaatggggc gaaaggttgg
    34381 ctgcaaattg caggattctc gatccaacct gccgaatacc taaaaatcat ttctatctgg
    34441 tacctgtctc tgactttatc taaaagacaa aacagtgtac aaaaagattt tcttgggact
    34501 gtgaaacgtc cacttgcaat ggttatcgga cttactgcat tagtcgctat tcttcccgat
    34561 tttggtaatg cggcagttat ctttttgatt attttggttc tgcttttagc cagcggagtc
    34621 aattatgtgt atactttgat tgtaggagta ggaggctttt gtctaagtac ttttacgatc
    34681 tggctgatca atatcacaaa cggaaagatc ttacccggac gtttacagta tatctataat
    34741 cgatttgcta tttaccaaaa tcctttctca gacgaattaa ataaagggca tcaactagtc
    34801 aacggctact atgccatgtt caacggagga ctatttggca ggggattagg taacagtatc
    34861 cagaaaaaag gatttttaca agaagcacaa accgatttta tttatgcaat cgtagtggaa
    34921 gaactgggag tgattatggg gattttgata ttagcgttgc tattctttat gattgtgcgc
    34981 attgtccttg taggtatccg ttcaaaagat ccgttcaatt cgcttttgtg cattgggatc
    35041 ggcgcaatgt ttttgatcca agtatttgtc aatcttggag gaattactgg cgttattcct
    35101 ttgacaggga tcacgttccc atttttaagt caaggaggct ccagtttgct gatgctttcg
    35161 atttgtgtcg gctttgtcct caacatcagt gcggatgaaa aacgcaagag cttaggttta
    35221 taataaaaaa agatgtagga gtggttcgat gaaaaaagtt ttagttgcta acaggggtga
    35281 aatcgctgta cgtgtatttc gtgcttgtac agaattagga attaaaactg ttggaatcta
    35341 tgcagaagaa gatgaatatt ccgtacaccg tttcaaagcg gatgaagcat atttagtagg
    35401 acaaggaaaa aaaccgattg atgcgtatct agatattgaa gggatcattt ctatcgcgaa
    35461 agaatgcgga gctgacgcta ttcatccggg ttacggtctt ttgtcggaaa acttgaattt
    35521 tgcgcaacgg tgcgaagaag aaggcatcat ttttgttgga cccaaactgc atcatttaga
    35581 tatttttgga gataaaatca aagcaaaagc tgcagctatc gaagcgggga ttgcttcgat
    35641 tccaggcaca gatggaccaa tcgcttctat agacgatgcc ttggagtttg cgaaacaata
    35701 cggttatccg attatgatca aggcagctct aggcggcggc ggacgcggca tgcgtgtagc
    35761 tcacgatgaa aagagtgcaa gagagggcta cgaacgtgcg aaaagcgaag caaaagcagc
    35821 ctttggtagt gatgaagtgt atgttgaaaa atacatcgct aatcctaagc atatcgaagt
    35881 acagattctc ggggatacgc atggaaacgt catccatctt tttgaaagag attgttctgt
    35941 tcagcgccgt caccaaaaag tagtagaagt agcgccttgt gtctctatga atgaacagca
    36001 acgtcaaaaa atctgccagg cagctgtcca attgatgaaa tatgtcgggt atgtcaacgc
    36061 aggtacagta gaatttcttg ttgaaggaga tgatttttac tttatcgaag tcaaccctcg
    36121 cgtccaagtg gaacatacga tcacagaaat gattacagat attgatatcg taacaacgca
    36181 actgttgatt gctcaaggtt tggatctgca taaagaaatc ggattgcctc agcaagaagg
    36241 aattaaatta aatggttcag ccattcaatg ccgaatcact acagaagacc cgttgaataa
    36301 ctttttacca gacacaggga aaatcgatac gtatcgttca cctggtggtt ttggcgtacg
    36361 tctggatgtc ggaaatgctt acgcgggcta tgtagtgaca ccgtattttg attcattgct
    36421 agtaaaagta tgtacgcatg gtgctacctt tgaaacagcc attcagaaaa tggaacgttg
    36481 cttgaaagaa tttagaatcc gtggagtgaa aacaaacatt ccatttatgc tcaatgtcat
    36541 cacacatcct gaattccaat caggaaatgc aaaaacaacc ttcattgata gtacagcaac
    36601 attatttgaa tttcctcgac tacgagaccg cggaaacaaa acgatgaaat atatcggtga
    36661 aattactgtg aatggttttc caggtatcga aagtggcgaa aaaccatttt atgaagaacc
    36721 acgtatgcct aaagatctaa tcacaagaac tgattacgta acggctaaga atgtattaga
    36781 tgcgaagggt gccgatgctt tggtcgaatg gatcaaagga caggaaaatt tgttgttgac
    36841 ggatacgaca tttagagacg cccatcaaag tctgctagca actcgtgttc ggacaaagga
    36901 tttcaagcag attgcacgtt tgactggaga aggtcttcct gaactctttt caagtgagat
    36961 gtggggggga gcaacatttg atgtggctta ccgctttttg aatgaagatc cttggcaacg
    37021 gttgagaaaa attcgttctt taatgcctaa tacgttgctg caaatgcttt tcagaggttc
    37081 aaatgccgtt gggtattcta attatcctga caatgtattg gtggaatttg tcaaagaagc
    37141 agcagcgcaa ggaatcgatg tatttcgaat ctttgatagt ttgaactgga ctccacaaat
    37201 ggaaaaaagt atccaagctg tacgggatac tggtaaaatc gcagaggcag ctatttgcta
    37261 tactggcgat atcaacgatc caagtcgggc aaaatacaat gttcagtatt ataaagacat
    37321 ggcaaaggaa ctagaacaac tgggtgcgca tatcattgca atcaaagata tggctgggct
    37381 gcttaaaccg caggcagctt atcgtttgat tagtgaattg aaagaaacga cagatctgcc
    37441 aatccatctg catactcatg ataccagcgg gaatggaatc atcacttatt ctgctgcttc
    37501 aaaagcagga gtagacatcg ttgacgtggc aatgagtgca atgagtggga atactagtca
    37561 gcctagcatg agcagcttgt attatgcact ggtcaatggt ccacggctgc cagaaatcac
    37621 gattgaaaat gcacagaaat taaaccatta ttgggaagat gtgcgcatgt attacaaacc
    37681 gtttgaaaac ggcttgaatg ctcctgaaac agaagtatat atgcatgaaa tgccaggagg
    37741 acagtattcg aatctacagc aacaggcaaa agctgtcgga ttaggtcatc gctgggatga
    37801 aatcaaacaa atgtatcata ctgtcaactt gatgtttggc gatatcgtta aagtaactcc
    37861 atcatctaaa gtagttggag atatggcact atttatggtc caaaatgatc ttacagaaga
    37921 agatatttat gaaaaaggcg aaacactaag tttccctgaa tctgttgtga ctttcttcca
    37981 aggagaacta gggcaacccg ttggcggatt tcctaaaaaa ttgcaaaaga ttattcttaa
    38041 aggcagacct gcattgaatg aacgtccagg tcttttggct gaatcagtcg acttcaacga
    38101 agtaaaaaaa gaattggcag aaaaaattgg ctatgaacca aaacaagacg aagtattaag
    38161 ctatttgatg tatccgcaag tctttttgga ctatcaaaaa gcatataatc aatttggcga
    38221 tgttacatta ctggacacac caacattttt ccaaggtata cgtttgggtg aaacaatcaa
    38281 tgtacaaatc gaacgcggaa aaacgcttat cattcgttta gatgaaatcg gagaacccga
    38341 tatcgaaggg aatcgcgtac tgttcttcaa tttgaatgga caaagacgtg aaatcactat
    38401 caaagataat tcgatcatca gtacggtcca aacccgattg aaagctgaac cgacaaaccg
    38461 agaacaaatt ggagcaacga tgtctggttc tgttttggat gtattagtga aaaaaggcga
    38521 taacgttaaa aaaggtgata cgttgatgat tactgaagcg atgaaaatgg aaacggccat
    38581 cgaagcacgt tttgacggag aagtcgcaca tgtatatgtg tcttcaggag acactatttc
    38641 gtctggtgac cttttgattg aagtgactga gaaataataa gcgaaaggtg gggaaacatg
    38701 aaaagactgg gtttgttttg gctgattctg ctattagtta ttgtggcatt ctacatggaa
    38761 ccagtcttgt ttccgccaaa acttgaagtg aaggaaaact ctgatcaaca aatatcaaac
    38821 caaatgacaa cgtggaaata ccaggagctt aaagcaactg gtttttctac ttatatcgga
    38881 aaaccgatcg atcagctgga aaaggatttt ggccaagcct atgatcgatt aactagcgga
    38941 tttggttttg aaacaagata ttatgaaaat aaagctagtc atctcacatt tgaagcgaac
    39001 atccaagaca gcagagtcac aactgttaaa gtactgcaaa cagggcctgc tgatatcgcg
    39061 ccgttttatt tagggatgac gatgcaagat cttacgaaaa tcactactat ctatactaat
    39121 ttcacttttg agtaccatga tacagaagtt ggaatcgaac taatggaaga ggatatgaat
    39181 tatcgtccgc taattgcttt tgataacgac acttttgcta ttttattttt tgatcaaaca
    39241 acaaacggcc tattttcagt tgtgtattta gataaagata gtcttttgaa actattgcca
    39301 tatcaagtgt ttggtgaagg ccttccacat tatcaagcag ataaatcggc tgattgggaa
    39361 tcaatcaatc gcgttaaaga acgaaaaagt acgactttat taaatatgct tagaagagaa
    39421 gacgaacttc ccatatacaa tcaaacactt gcctttcaaa accacagtca gctgctacta
    39481 catgattttt tgacaaggcc tgaggaaata ttgtcagagg aacgtatggc tgattggcaa
    39541 aaatcgctag gcagtgctca aacgacagtg aaattctcac tgacgaatga tgaattggag
    39601 aagttaatca gtaaacaaaa attagaaaat actagtgggc tatttattca tccggcgatt
    39661 gacgctactt tttcgttttt atattggtac agcgatcctt acaaccatga ccgtttcatg
    39721 gacccgggaa cggattctgt aggcattgct ttttctaaag aaaatatgtt agtcttattg
    39781 caagaagaaa acggagaaag tagtgatagc agtgatcgtt aacgaagagc tgtttcaact
    39841 ggaggatcaa tgcctccaag tcgctgaaat gataaaaaag agtaaaacga tggcttctta
    39901 tcttgaacat aaacagtcaa tggaagaatc tgcaaaagtt tgccagttga aagaagcgtt
    39961 cttgtctaag aaagaagcat ttgaaaatgt agcggcatat ggtgagtatg cacctgatta
    40021 tcgtgaaaaa aaacgagctg ttcgaaaagc aaaaagacag cttgatatgg atgagcatgt
    40081 tgcagctttc cgatatagtg aaacacagct gcaaagtctg ttggatcaaa ttgtccaagt
    40141 acttgccgaa gaagtttcta atgaaatcaa agtagatgca ggtagcccgt tttttgaaac
    40201 gaaaaaacac tttggatgcg gaggtaattg tcatgcaatt agacaatagt gaatttgaaa
    40261 taacaaaacg acgcgggctg atcgtatggg tctacagctt aaaacaatta aagaatctga
    40321 aaaagttcgg cttgttgcat tatgtctcaa gaagaatgaa atatgtcgtg ctttacttaa
    40381 atgaagagac attggaagaa acagaagaac gaatccgtaa attacatttt gttcgaaacg
    40441 tagaacgttc ttaccgaccg gatatcgaaa tgaattttgc cgaaaaaata ggaaacaaaa
    40501 cagtattaaa agacgaaggt ttcgaaattg aagagctaaa tacagaaatc cgattagctg
    40561 aacatcttta aaaatctctt atgagcagtt tttaaataaa aaataacttg gataacgatc
    40621 gatttttgat cattgtccaa gtattttttt ggtatactag taccagtacc atttctaagg
    40681 agtgagtaga tgcggataat atcaggaaat tatggcgggc gccgtttaaa aagtttagca
    40741 ggggcgaaca ccagaccaac tacagataaa gtaaaagaat ccatattcaa tatgattgga
    40801 ccatattttg atggagagac agtattggat ctgtttgcag gaagcggtgg tttagctatc
    40861 gaagcagtat ctagaggctg cagtcatgcg gtatgcgtag acaaaaatta ccaagcgcta
    40921 aaaatcatca aagaaaacat cgaaattacg aaagaaccag agaaatttac cacaataaaa
    40981 cttgatgcgg acaaagcaat cgaacggcta gcagcggaga aacaacaatt cgactacttg
    41041 tttcttgatc cgccatatgc aaaacaaaaa ataatcgatc aaatccataa aatggaagaa
    41101 ctgggacttt tttctaaaac cgcagttatc gtatgcgaaa cggataaaac agtcgaattg
    41161 ccagaaactg tggctggatt ccatcaaata agaaaacaga tttatggcat aacggccgta
    41221 actatctata gaaaagaggg aaatcaatga aacgtgcatt attcccagga agttttgatc
    41281 cttttacaaa aggtcactta gatacggtgg aacgtgcggc taaattattc gatgaggtag
    41341 taattggtgt ttttatcaat acttcaaaga aaagtttgtt tcccccagaa gaaagaatga
    41401 cattgatcac aaaagctgtt tctcatcttc ctaatgtaaa agtcatgcat caagaaaatc
    41461 aattgacggt agaaacagca aaagagattg gtgcagatgc gttgatcaga ggcatacgaa
    41521 gtatcaaaga ctttgaatat gaacgagaga ttgctcagat gaatcatcat ctatatgatg
    41581 aattggaaac tgtcttctta ttagcaaaac cagaatatag tcacgtgagt tccagtattt
    41641 taaaagaagt actgcacttt ggcggagatg tgagcagcta cttaccgcca gtgatcaacg
    41701 aagctttagc tggaaagcgt gaatcaaatg aaagctaaac aatggttgaa aacagtactg
    41761 attatcatat ttggaatgtt gatcattgga tttgtagtag ttcccttgcc gtattatgta
    41821 gaatcaccgg gagccacgat cgatctgaaa gaactaatta cggtcaatga taaggaagat
    41881 aaaggttctg ggtctttctc tcttacctct gttggtatca ggcaagctac aggtttctta
    41941 gctttaaaag ctaaaatgac cccttttgaa gaattgatca gtgaagaaga attgactggt
    42001 ggggcgacaa atgaagaata taatcaaatg caacagtatt atatggattc ttcccaaaat
    42061 gcagcaatcg aacaagcgtt aaaacttgca gacaagcctt ataaaatgga attcaaaggc
    42121 gtatatgtca tgagtgtaga gaaaacatcg aatttctttg gcaagctttc agttggagat
    42181 acagtaacaa aagtagacgg gaaaagcttt caaagtacag aagcatttat ggattatgta
    42241 aaaagccaaa aagttggaca aacaatcgaa atcagttatt tgcataatgg tgaagaaaaa
    42301 acagcttctg gtgatctgat cgagttacca acagataaaa aggcaggaat aggtatcacg
    42361 cttactgacc ataccgagat cgaatcagat acagatgttc gtattaattc tggctctatc
    42421 ggtgggccat cagcgggatt gatgttcact ttagaaatct atgaacaagt cactggtaaa
    42481 aacttgcgac atggtaagca aattgcagga actggaacga tcaacagtga aggagaagtt
    42541 ggccgaatcg gaggaatcga taaaaaagtg gcaagtgcgg ataaagctgg cgtagagatt
    42601 ttctttgcac cagatgatac gatttcagac gatgttaaga aagaatatcc tgaaataaaa
    42661 accaactacg aagaagcaaa agctgccgct aaaaaattga attcctcaat gaaaatcgta
    42721 ccagtaaaaa cagtacaaga agcgcttgac tatctagaga aaatgaaatg aaactaaata
    42781 attaaagagg ggttgtgaca cgagttctgt cacaacccct ctttttcgtc aaaa
//
LOCUS       DACDAF010000016        37146 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.016, whole genome shotgun sequence.
ACCESSION   DACDAF010000016 DACDAF010000000
VERSION     DACDAF010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37146)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37146)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37146
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.016"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..420
                     /locus_tag="IVZ69_000780"
     CDS             <1..420
                     /locus_tag="IVZ69_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAP8182888.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(504..1226)
                     /locus_tag="IVZ69_000781"
     CDS             complement(504..1226)
                     /locus_tag="IVZ69_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP8182889.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(1216..1953)
                     /locus_tag="IVZ69_000782"
     CDS             complement(1216..1953)
                     /locus_tag="IVZ69_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182890.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            complement(1965..2957)
                     /locus_tag="IVZ69_000783"
     CDS             complement(1965..2957)
                     /locus_tag="IVZ69_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP8182891.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            complement(2972..3715)
                     /locus_tag="IVZ69_000784"
     CDS             complement(2972..3715)
                     /locus_tag="IVZ69_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8182892.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     regulatory      complement(3789..3893)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3956..5278)
                     /locus_tag="IVZ69_000785"
     CDS             complement(3956..5278)
                     /locus_tag="IVZ69_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP8182893.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     gene            complement(5265..6230)
                     /locus_tag="IVZ69_000786"
     CDS             complement(5265..6230)
                     /locus_tag="IVZ69_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182894.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            complement(6227..7765)
                     /locus_tag="IVZ69_000787"
     CDS             complement(6227..7765)
                     /locus_tag="IVZ69_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HAP8182895.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            complement(8181..8468)
                     /locus_tag="IVZ69_000788"
     CDS             complement(8181..8468)
                     /locus_tag="IVZ69_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182896.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            8602..9270
                     /locus_tag="IVZ69_000789"
     CDS             8602..9270
                     /locus_tag="IVZ69_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP8182897.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            complement(9561..10301)
                     /locus_tag="IVZ69_000790"
     CDS             complement(9561..10301)
                     /locus_tag="IVZ69_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182898.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(10431..11378)
                     /locus_tag="IVZ69_000791"
     CDS             complement(10431..11378)
                     /locus_tag="IVZ69_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8182899.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            complement(11507..12271)
                     /locus_tag="IVZ69_000792"
     CDS             complement(11507..12271)
                     /locus_tag="IVZ69_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP8182900.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            complement(12275..12664)
                     /locus_tag="IVZ69_000793"
     CDS             complement(12275..12664)
                     /locus_tag="IVZ69_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182901.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            12799..13341
                     /locus_tag="IVZ69_000794"
     CDS             12799..13341
                     /locus_tag="IVZ69_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HAP8182902.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13489..14121
                     /locus_tag="IVZ69_000795"
     CDS             13489..14121
                     /locus_tag="IVZ69_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182903.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(14255..14380)
                     /locus_tag="IVZ69_000796"
     CDS             complement(14255..14380)
                     /locus_tag="IVZ69_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8182904.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(14514..15407)
                     /locus_tag="IVZ69_000797"
     CDS             complement(14514..15407)
                     /locus_tag="IVZ69_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HAP8182905.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(15589..16515)
                     /locus_tag="IVZ69_000798"
     CDS             complement(15589..16515)
                     /locus_tag="IVZ69_000798"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HAP8182906.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="IVZ69_000799"
     CDS             complement(16600..17361)
                     /gene="pflA"
                     /locus_tag="IVZ69_000799"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HAP8182907.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="IVZ69_000800"
     CDS             complement(17605..19836)
                     /gene="pflB"
                     /locus_tag="IVZ69_000800"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HAP8182908.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(20113..22563)
                     /gene="parC"
                     /locus_tag="IVZ69_000801"
     CDS             complement(20113..22563)
                     /gene="parC"
                     /locus_tag="IVZ69_000801"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HAP8182909.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(22575..24620)
                     /gene="parE"
                     /locus_tag="IVZ69_000802"
     CDS             complement(22575..24620)
                     /gene="parE"
                     /locus_tag="IVZ69_000802"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HAP8182910.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(24786..25220)
                     /locus_tag="IVZ69_000803"
     CDS             complement(24786..25220)
                     /locus_tag="IVZ69_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HAP8182911.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            25347..25985
                     /gene="plsY"
                     /locus_tag="IVZ69_000804"
     CDS             25347..25985
                     /gene="plsY"
                     /locus_tag="IVZ69_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HAP8182912.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(26117..26992)
                     /locus_tag="IVZ69_000805"
     CDS             complement(26117..26992)
                     /locus_tag="IVZ69_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAP8182913.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(27074..27865)
                     /gene="codY"
                     /locus_tag="IVZ69_000806"
     CDS             complement(27074..27865)
                     /gene="codY"
                     /locus_tag="IVZ69_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HAP8182914.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="IVZ69_000807"
     CDS             complement(27883..29283)
                     /gene="hslU"
                     /locus_tag="IVZ69_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HAP8182915.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="IVZ69_000808"
     CDS             complement(29297..29845)
                     /gene="hslV"
                     /locus_tag="IVZ69_000808"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HAP8182916.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="IVZ69_000809"
     CDS             complement(29882..30787)
                     /gene="xerC"
                     /locus_tag="IVZ69_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HAP8182917.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="IVZ69_000810"
     CDS             complement(30985..32361)
                     /gene="trmFO"
                     /locus_tag="IVZ69_000810"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HAP8182918.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(32330..34408)
                     /gene="topA"
                     /locus_tag="IVZ69_000811"
     CDS             complement(32330..34408)
                     /gene="topA"
                     /locus_tag="IVZ69_000811"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HAP8182919.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="IVZ69_000812"
     CDS             complement(34530..35387)
                     /gene="dprA"
                     /locus_tag="IVZ69_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HAP8182920.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(35443..36210)
                     /locus_tag="IVZ69_000813"
     CDS             complement(35443..36210)
                     /locus_tag="IVZ69_000813"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HAP8182921.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDVRSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="IVZ69_000814"
     CDS             complement(36203..37063)
                     /gene="ylqF"
                     /locus_tag="IVZ69_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HAP8182922.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
BASE COUNT        10090 a         7906 c         6368 g        12782 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacaac ctgttgtaca agaaacggtt
      121 caaacggaaa aacaagcagc gcctgttgct gaaacacaac ctgctcctgc tgtaacagaa
      181 actgctgcta ctccagcaag cacaagctct gcaaaagaat ggatcgcaca aaaagaatca
      241 agcggttctt acacagcaac gaacggacgt tacatcggac gttaccaatt agattcttct
      301 tacttaaatg gtgactactc tgctgcaaac caagaaagag tagcagaaca atatgttact
      361 tcacgttatg gttcttggga agcggcgaaa gcattctggg aagcaaacgg ttggtactaa
      421 gattcattta ttaatcaaac agtttacttt tatacaaaga aagccaaaaa gaggtgcgac
      481 actagttgtg tcacatctct tttttattta cctaatctaa tgaaacgttc caagttttga
      541 taagtatttt ttttaacttc ttcaactgat agctctttga tctcagcgat tgtctttaac
      601 tgttcttcaa gcagtgagac ataatctttt tctgaaaaaa tcccccctaa agcccactct
      661 gctgcatgta gtccatccgt ttcaataagt aagtggtcga ttgggactgc tttagctagt
      721 tgccagactg ctggattctt tttcaaatca agaccaatgc tgaaataaca gcctaaatca
      781 atatagtctt gttgatagtc caaagaagaa taccaatgga tcaaatagtg attagggtaa
      841 gcttggatat aatttaagat ctctttttcg catccttttg tgtgcagtac aacaggtttc
      901 tcatttatgg ctgcaaaagc aagctgtcgc tcaaatactt ttttttgtgt agtcatcggt
      961 acattcgtcc aaatattatc taaccctatt tcaccgatga tccttgcttt tttcaaaaaa
     1021 ggctcaactt gttcaaacgt atagctatct gctttccaag gatggatacc gtaacttaag
     1081 gcttgagtct tacttgctgc aagctgtctg ttttccttcc attcttctgg cgaatcacaa
     1141 ttgatgatcg tcaaaatcgt gtgttcctgc tgaaggagtg ctaaactctg actcccatct
     1201 aaatgacaat gagcatcact taacatctaa ttcacctgcc aataactgat aaatcgtttg
     1261 cttcaactct gattgctgca gtagccattc acgtgaccgt cgtttttcag gcacttgaat
     1321 ctcagcaatc acatgtgccg gacgggcgga aagcacaaga atcctgtctg ataaataaat
     1381 tgcttcttcg atatcatgcg tcacaagtaa agtagtccgc tttgcttttt taggcagctt
     1441 caacatccag tcttgcatct gccctctggt catagcatct aacgctccaa atggttcatc
     1501 aagaagcaag taagaagaag gattcatgat tgttcgtaac aaggccgttc gctgcttcat
     1561 cccgccagat aattgttccg gcaaaaaatg ttcatagccg tttaacccaa agatatccag
     1621 ataatccctt acttgttctt cattgattgt tagatgattg attttttgat ataacgtaac
     1681 gttttgatag acgctcagcc aaggaagtaa catatcttct tgcggcatat aactaaatgc
     1741 tgtatggaga ccagttactt tttgatcgtc tactttgatc gttccagaag tcataggctg
     1801 gactcctgtt aaagttttca gcaatgttga cttaccggct ccgcttggcg cgacaatcga
     1861 tgtaaaggta tctttaggga tagtgaaatg gatgtcttct aatattttca ggttttcaat
     1921 gactacattc aagtggctga tttggattga catatctatc actcctattt tataaactga
     1981 ttagtgaata gttcttgcga aggtacatct tgcttgatca atccgttttc ctgcataaaa
     2041 gctgtataat tgcgccaaac tttttcttcc atcaatcccc aattctcagg atcatccgta
     2101 taattttttg acaagaatgc ttgtgattct tctaaaaacg tccgatcatt ttcttttgca
     2161 tatttttgca acagtttagc actgtcattt ggatccttaa tagcttcctg atagcctttt
     2221 ttcgtggcat ccataaaaga ctgtaccaat tctggatcac ttttgatcag ttgatcattc
     2281 gtaataatta ccggagtata gtaatctaac cgttcatcta attctttcaa tgggatatag
     2341 tttagttcaa tacccgcttc ttttgctttg atcatatccc aaccttcaaa gtaccattgg
     2401 atatctgagg attttcctaa gctttctggc ccttctccat tgcttcctac cattgtcagt
     2461 tttgaaaagt ccccgccgtc tttttccatc acagctttta agacagcttc ttcacttgga
     2521 ctttgccaac ctgcatatgt ttttccttca aaatcttttg gtgaatggat gttactgtct
     2581 gatagggtgg cgaatccaga agtattatgt ttgatcactg tagcaattgc tttgactggt
     2641 atattctgtc catctgcgtg agcataagtg acatcttctt gataacttac accaaattgt
     2701 gctttgtccg cacctactag accaatactt gtcgaattat ctcctggttc gatgatttgg
     2761 acatttaaac cagcctcttt ataatagcct ttttcttttg ctaggtagat gccagtatga
     2821 ttagtattcg gtacataatc caaaacaagt gtcacttttt tcaaatcctt tatttcttgt
     2881 ttgctacttg tttcttttgc agtgccacaa gcggataaaa gcaacagtag cggtaataaa
     2941 agccataatt ttttcatttg atccccttct cttaaaaaat ataaagcata cgataatacc
     3001 cttttttcaa taatgaacaa gcgccattca gcaataaact caatagaatg acacaaatga
     3061 tcgcagcaaa aactttatcg atctggtagc tgttttttac gcgtatcatg taatacccta
     3121 agcctgcttg agcgcttagc cattctccaa cgactgctcc gctgacacaa taagtagcag
     3181 ccacttttaa accggaaaag aagccggata aacccgctgg tattttatat attcgataaa
     3241 tcttccctgt atctgccccc atcgttttca aaaagatgat ttgctctttt gatactttcc
     3301 tcaatgtatc cgaaaaagaa actacgatcg gaaaatagct tatcaagaca acaaggatca
     3361 cttttggaag cataccgaaa ccaaaccata gggtaagtaa tggccctaac accatgattg
     3421 gcaacatttg tgaaatcact agtaacggat aaaaagacat ttctaaaaac ttccaataat
     3481 ccattgccaa ggcagtaata aaagaaagaa cgctagctat taccaaacca agcactgctt
     3541 catttaatgt cgtgacagaa tgggaaagta atacttgtgc atctgccgct aatgcagaaa
     3601 atacagcagc aggtccgggt aaaataaagg caggtatttt ccaaactatg acaacaatct
     3661 gccaaataat taaaatgaat gccatactga ctgctggata aagatttttc ttcattttgt
     3721 tacctccttt cttctaatat gaataacaaa aaacgcttga aatgggcacg acatagtaac
     3781 ccgcttcaag cgtctgctat gtttctccct tcaccagtat taactgacag gttcaatggg
     3841 tctaagttca caacttactc tcatgtcgtc tacgacatcc ccagaaacag gtattcattt
     3901 tttaaagtgt agcacaagaa ggaaaaagca acaagcgctt tagttatcat gctgattatt
     3961 tcaataaata ggagagatca cttgccaatg tcggataccc catgatatag ctatccaact
     4021 cttttttagt caatttttga ttgatgacga gtgtcaaatc atcgatcaat tcgtctgctt
     4081 gctcgctaat cactgcagca ccaatcaaat aattttgctg gtcaaaggtc aattcagcct
     4141 tagcaactgg ttcattgaca cgatgatagg tgaaccaact ggtaagatcc atctctacca
     4201 cttgatctga cgaagaggcg tgactttttg taactcctac ttcagcaagt ttaggactgg
     4261 cgtagacgat cgtaggtata atcggatatt tgataggttc gcttgttgca tccgttatcc
     4321 gcttagctac ataatttcct tcaaaagtgg cgactggtgt caattttggg gttttccttg
     4381 aaacaatatc tccacacgca aaaatttttg gattgctcgt ttgcagataa tcattgactg
     4441 caattccgtg tttatcaaag acgatattcg cttgctcaag tgctaaagat tctgtattcg
     4501 gctgtctccc agtcgcacaa aaaatcatat ctgctactaa ttccgtctct tttccgacta
     4561 aacgatagcg agtaccttct gaaatgatct tttgggtttc aacaccaaaa gcaaactgaa
     4621 tgccagatgc ttccatttga tggacggctt cctctaccaa agacgcctca aattctttta
     4681 atggccgttg attatgatgg acaatggtta ctttgctccc tgcagcattg gcaatcgtag
     4741 ctagctcaaa agcaatataa ccaccaccga taaaaatgat ttctttaggc agtacaggca
     4801 atgataaaaa gtctgcacta gttttcaagt attcctttcc ctccactggt aagatcgtag
     4861 gtctttgccc ggttgccaaa actaagtaat ccgcatggaa gacttcttcg ttgacttcaa
     4921 tagatgaatc atccaaaaaa cgagcggttc ctgaaagatg atcgatttca gcttctgcta
     4981 attgtttttt tcggctttct gggactggat ccgtaaatgt tcgtttgaat ttttgaagtt
     5041 cttcccagtt ggcagttggg atctcgttaa aaccttttcc actcaattgt tttacccgat
     5101 tacgtgcctc tactgcactt aacaagactt ttttaggatc acatccacgg ttaggacaag
     5161 tcccgcccca tagatcttct tcgaccacta gtactgtttt acctgcttct ttcaatccat
     5221 aagcagcact taagccgctc acacctgaac cgatgatgat tgcatcatat gttttcattt
     5281 ccttcctcct ctcgacttaa aaaagcaaag atttctttac ttgtcagcga cccaatactt
     5341 ctttgctttt ctactatcac aatgcttgga tacaccgaaa gaagcgaata tacttctttc
     5401 ataggcgtat caaagcaaac ttgttgacga gcattttctg gtatttcatt taagaaatat
     5461 ccattgacga ctaaatcttc tactcgccac tctttcgtct gtttcggttc atcaaagaaa
     5521 tgccgaacgt agtcgttttt aggattcatc aataactgct ctggtgtgtc acattggata
     5581 atttctccat ccttcataaa tgcaatacga tcacctagct tgattgcttc ttccatattg
     5641 tgcgtaacga aaacgatggt cgtgcccaat tcttcgtgta aggacaaaac caattcttgt
     5701 aatgagtttc ttgaaatcgg atctaatgcg ctaaatggct cgtccatcaa aatcacatct
     5761 gggcttgcag caatagctcg gatgatcccg atccgttgct gttctcctcc agacaactct
     5821 ctaggcatac gatctcgata aatatcagga gataagccaa ctttttgaag aagttcatct
     5881 acacggtctg ctcttttctg cttttcccaa cctaacattt cagggatgac ttcaatattt
     5941 tgcttgactg tcatggtcgg gaacaaagcg atttgctgca gcacatatcc catattccac
     6001 cgcattttct gcagattata ttcatttaac gattttcctt tgaagtagat gtctcctgct
     6061 gatggtttag ataatccatt gatcattttc aaagtagttg tttttccact accggaagga
     6121 ccaaccaaaa caaagatttc tccttttttg attgccagat ttaggtcatc gatgacatac
     6181 tttccatcat actttttttg cacatgtttg aactcgatta atttagtcac tgatcttcct
     6241 cctttactaa tccttcattt ttcaggaaga ttcgtgctac ttctgtcggc tttttctttt
     6301 cgacattgac ttggtaattc atatcaatca tttgatcctc tgttattttt ccgcttaatt
     6361 tattcagtgc tttaacgatt tcaggatgtt ctttagcaaa atcttttttc atcagcggtg
     6421 cgccttgata agctgggaat aaccctcgat catcttctag agtcactaga tcgtactcct
     6481 tgagctggct atctgtggaa taggcatcca caatattgac atctccatta ttgattgctt
     6541 ggtaacgcaa acttggctcc atgctttgta cacttgaaaa attcaagcca tatgcttctt
     6601 ggattccttt atatccatct gaacgatcaa taaattccag tgtgaatccc gctttgatct
     6661 gatcagagat agctgccaaa tcggaaatct ttttaagttg atgttcgttc gcaaaagatc
     6721 tcttgactgc caaggcatac gtattttggt aagccattgg ttttaataat gtcatatcga
     6781 attgcttatt caataattct tctgcttcgt catatgtttt ttcttttgtc aaatcagcac
     6841 ttttcattgc ttcaggtacc ttcaccaagc tttctaggac agtacctgtg aactcaggat
     6901 agatatcgat ttgaccttga tccagtgcat tgaacaaaaa actcgtcttg ccaaaattcg
     6961 gttttaattc aacttctgtt tttgtgttgt cttcaatcaa ttctttatac atttggatca
     7021 ggatttcagg ttccgctcct aattttccag caatcgtgat ggtttcattt ttaaacaagg
     7081 cagactgata taaagaaacg ccgccaaata aacacaccac tgctgctaaa gtaatgatgg
     7141 aatatcgagg tttcttatgc tgcaaccagc gaatcagtcc gctgaatata attgcaagca
     7201 aggcagaact gatcgcacca atcaatgtca aaacaggtgt atttcggtca atacctaaca
     7261 aaataaatgt ccctaatcca cctgctccga tcaatgctgc caaagtagcc gtaccgatga
     7321 ttaaaactaa ggcagttcgg atacctgaga taatgacagg taatgcgatg ggaagctcta
     7381 ctttcagcaa gcgtctcatt ctggacatac caaatgctac cgctgcttct tcaatagacg
     7441 ggtcaatttc agctagacca atatacgtgt tttggaaaat cggaagcaaa gcgtaaataa
     7501 caagtgcaat caatgctgga acagttccga tccctacaaa tgggataagt aaacctaata
     7561 aggcaagtga aggaatcgtt tggagcacac ccgtgatctg caataagact tctgccattt
     7621 ttttatgatt ggctgcccaa atcgctaaag gaatagcaat cagtgctgca atcagcaaag
     7681 aaatgagaga aatggacaga tgttgaaatg cagcttccag caactcgcct tttctttcac
     7741 ttaatgtttg tataaaatta ttcatgcgac cttcctttct gttattcttt aagtataaac
     7801 atttctttcc tttttcccaa ctaacttgtc ttgccttaac cttacagcac gaacaaaaaa
     7861 aagaaaaaaa tacctctaaa tatgctgaca aaaaaagaat ccaagcaaca aagtcggatc
     7921 aactttttgg ttctcgtttt ttcactacga ataccataaa aatctatacg aaattgtcac
     7981 ttggaatcag ctatatcttt tttacacaca caacttttat tttaataaaa agaaacagcc
     8041 aataaagtag aaatctcgtg ggggagaaca cctttattgg cctgttcaac gaatattata
     8101 ctgtatcatg acactttttt gccaaaaatg taaaaaatgg ttgttttgac atcataaacg
     8161 tcttgttttc ttatttttac ttatatcacc actttatttt ctatctcttt cactccataa
     8221 agaggaatga gttcttcttt tgactgataa taaacagctt tctcacggtt cttcatcaaa
     8281 aaaagaaaga tgtctttcat agcaagtggt gctttgccgt gttcaaataa aaagataaat
     8341 tgatttgctt tatttatctg gaccattgtc acaggcacca gtttttgttc ttgagccaaa
     8401 aaaactcctt gatactctgt ttttttgggt gattttgtaa gaattgtcaa taagtctgct
     8461 gctcgcattt ttccactcct tatttgataa ataaaaagaa acagccaaaa ataatttttt
     8521 ttcattttcc tcttgaagta agagtataag tcagtataat aaagaagttg ctgaaaattt
     8581 tcaaaagaaa agaggctaga aatgaaaaaa ttaaatttat ttacagaatt gtgcggaatc
     8641 attttaggcg caggaatcta cggattagct gtgacaggaa tcaatattcc atctaagctg
     8701 gcagatggtg gggttactgg tattgctttg cttttgcata atctttttgg attcgctcct
     8761 tctgtcactt cactgctttt taatttacct ttattgctta tctcattgtt tctttttgga
     8821 aaacacgctt ttctccggac gatcgtcgga acatttgcgc tagttttctt tttacattta
     8881 tgggagagcc ttcatataca ttttgctgta gatagtctac tgatcaatag tttgatgaca
     8941 ggtattcttt ctggcattgg ttgcggtctc gtctttcgat tcggcggaag cacaggcgga
     9001 acagatatca tttatcaagc cattgaaaaa tattttcata ttaagattgg caaaagtctt
     9061 ttcttgatta cttttggtat tttagttgtc tccttgcttt atttggatct cacacatttt
     9121 ctgtatacat tacttagctg ttctattcta tcttatacat tgaataaagt gaagtatctg
     9181 gaaattggat ctgttttgcc ccaattggaa gcaaaacaga ctacagaaac atttgaacca
     9241 cttgatcctc ttgaacagtt agagcactga ttcttatttt tcactacttt atttaattta
     9301 cagaaatatc attatgtaaa ctaaaatgat attattcagt aaaatcttct ttataaaaaa
     9361 ataaactatt tttgcaaacg atctgcgaaa atagtttgtt tttttatttt gccattattt
     9421 tcttacttat tgggagaaaa aattcgctta aactcaaaaa aatttgagga tacgatataa
     9481 actttcggat agagtataaa ataaggaaac gccgcagcgt ttcctttcca actgtagccg
     9541 aatataaatt tgtatatcac ttatttaaaa tagctatttt ctcccaaaga gtttccttga
     9601 tcatcgatca atccttgtaa tgagcgttct aagataccat ggcttttttt cgattttttt
     9661 tcttctgact gctttgtttc ctctaacgtt tttgttcgat tgaatgttcg tacagacggc
     9721 tcaccatttc ttttttcttg atacggcgtc ggttctgtat cgaacaacag ataagagtca
     9781 tccgtttttt tcatcgattc gattaaatga tcctcagaaa ttttgctttc tctagggtct
     9841 gggataatcg atgcgggtac atatttagga acaaaataag aacgctcccg caccttcgtg
     9901 tcaacagatg cgtttcgtgt agtatgcttg gactctgtcc ttgtttcact ttgtctgaca
     9961 gaacgagagg aatcaccaaa aagttttttt cgtcctgtcg atgtgatttc tgattggtaa
    10021 tggccggtat aatccggtaa ttttccttta tgcttttcca aattttcctt acgcggagct
    10081 gacttcaatc catttgttgc acgacgcttg cgacggattt tctcggtgtt cgtgttcgtg
    10141 aaatgaaatt ctttcatctg ttcaaacggg gactgattct gttcagtcaa aagatcttct
    10201 tgtccgtcaa ataatactcg cttcttgtcg ttggttaatt ttacgcctaa ctcatcatcg
    10261 tacgcaggaa aacggaaatg ttttcgtctg atttctttca ttcaaaccat ccttctcaaa
    10321 aatggaactt ttctcaataa tagcacagat tcattgtttt cagtagcaat gcgctgatta
    10381 ttttaagaaa atagcgatga atttcataaa tatatatata gtaataagac ttaattcgtt
    10441 gtctctctga taactagttc aggaaaaaaa cgacgataac cttgactcgc ccctttttct
    10501 tctatttttt ttaacaacat ttctccacat acttcaccca tacgtataat atcttgcttg
    10561 atcgttgtca atttaggtga actgatttgg tctaaaaata ccccatcaaa tccaatcaca
    10621 ccaaattctt cgggcaagtg tcctccagca tttataatcc ctcttactgc tcctagtgct
    10681 agccgatctg aactacatac aaaacaagtt ttatctgtaa aatctgccca gttttctgtc
    10741 atatatcttt ctacttctgt cgaatgattt ggaaaccgca agattttact aggaagatca
    10801 acttccttca tcacagataa ataaccagtt tcccttgaaa tttcaaaagg ctcgtccact
    10861 tcgataccga tataaataat cgtttgataa tctctttcta aggcatattg cgttgctttt
    10921 gctgtaccat attcattatc gctgtctaca taatcatatc cttcagaatt ttccccaaac
    10981 aagacaactg gtttttccaa acggtcgatc caatcgaagt ctttttttct gacacctgtg
    11041 atgatgtatc catcacaaga accgacgtcg aaggcatcat ttgtaactaa ttggagagaa
    11101 taatgcgctt taccgatccg tttagcgatt cccatcagca aattcatgta atagggctca
    11161 gttgtgtcga tttcttccag tataaataat ttgatgatct gcgaccgatt cgtgacaagt
    11221 gcttttgcag caatatttgg acggtaatcc agttcagcca ttgctgagaa aactaactct
    11281 ttcaattcgt cagtcacctg ttccggatga ttgatgactc gagagaccgt catttttgaa
    11341 acattggcac gttttgcaac atctgctaaa gtgggcatgc tctcttcctt tctaacatgt
    11401 tgtcattctt actatcaatt ataccaaatt ttcctaacag agtttattat agcccaaaat
    11461 aaaaaacgga aaatcctcta tcgtcatgag tgattttccg tttcaattat ttatactttt
    11521 ttatcaaatt ttttgctaaa aaagtggaag cttcttccat tagtggtatt tgtaccatat
    11581 gtcgctgtgt ttttgaggaa cgaaaaacaa tttcttttcc gtaagactta tgccgatttt
    11641 tttctacaaa tcgttccgtt tgtatataag ggattttttc gtcagcttgt ccatgccaaa
    11701 agaacagagg acgtccagct aacttttccg gctgcaatga caaatcatag ctcttaaccc
    11761 atgaaatcaa atcaaaatag tcttttggta cgacataatt atattccgat gcgcgcctta
    11821 cgatttcttt tccatattcc aaaggtgcag gggaacccat caaacacacg cccgctacta
    11881 tatgaggatg tttagccaac aaggcgcatg ttgtcattcc ccccatcgaa accccgccaa
    11941 ctgcaagctg atcatgtaga agacctcttt tttctaaatg cttgataagt gtgtcaaatt
    12001 caaacagatt tccgtagata ctatcccaaa atgtatagga tggaatagaa gaaaccggct
    12061 gtttgcgctc cccatgattc atcgcatctg gcaggatcac acgaatgccc tgctgcgcaa
    12121 tttttcttcc ttgcgtcaaa actaactcct tacttgtctg ccatccgtga taatagatga
    12181 caacgggaat acgttcctct cttaattctt tcagaacaac ttctaacact ggaatatgat
    12241 ggacagaacg tttcaatata attggattca attgttactc acctattttc attaaatttc
    12301 ctgatcgcca tagcaaccat gctccaacag ttgtctggaa caggttcagt gtaccaaata
    12361 atataaatgc aggactgaat ggctcgggaa ataagcacag agaacaaagt cccaccactc
    12421 ctaatgctag cgaaaggagt ggataaatag aaaaattcaa aaaactggca acgctaccga
    12481 aaatattacc aataaacagt atcaaaaaga aaaaaacgct taaaattaaa ccatctgtca
    12541 gcgacatctg aaaaacaatg ttctctacct caattggctg ttgaatcgaa tagacaccta
    12601 agtatatact gagaaggaga cttagcacgt ggctggcaca aaacacacga ttgaccgttt
    12661 tcattttaat cacctaacct atctttataa ttctattata atcattttat catttttttg
    12721 tatgtataaa gtttcaattt ttcttcactt acgatttttt ttgatattgt tgttatataa
    12781 atgaaaggag ttttacaaat gattgatcca aaaatgttgg ggatgatctt cctcattaat
    12841 tttgcttata tcactctgaa cacgttacgt ttcatgttga caatgaaagg ctatcgactg
    12901 attgctccac ttgtcagtat ggtcgagatc acgatttata tcgtcggctt atcccttgtt
    12961 ttagatcgtt tagataatcc actgaattta tttgtctatg cgttaggtta cgcagtaggt
    13021 atcagtgtcg gaattttgat tgaagacaaa ttggcattag gatacatcat ggtcacaacg
    13081 attttgccag caaatagcgc agaagataaa agtttgccgg gtatactgag agaacacggt
    13141 tatggtgtga cacagacttc tgcaatgggg ctggaaggtg agcggctagt tctcgaaata
    13201 ctttctccta gaaaaagcga acgtgaactg tatcgcctga tcaaagaaat cgaagagcgt
    13261 gcttttatca tttcttatga gccaaaatat atttcaggtg gtttctggac taaaaaagtg
    13321 agaaaacgac aaggaaaata actcacaaac ttaaaaactg tctaatatct aaattaaatt
    13381 ttaaatgtta gacagttttt atttattatt ttgattaaaa aacatcgaca tatactcatc
    13441 aatttgttat tatactttat atacttatca atttaatttg gagatattat ggaaattcaa
    13501 cgtagaacca ctaatttttt acatttaggc tctttttttg caactttgac gatcttattt
    13561 tttctatgtt attcatacct taagacctca catgcgcctt ctagtgcatt aggctggttg
    13621 cttttggatc attctgatat cacagaagcc gaagaaaatc cgtttttttt gattttgtct
    13681 tctctttgcg gcttactgtt ttctgtttat ttcggtgcct atttttttca tcgacatcct
    13741 ggtacgttaa acgaagcttc aagcgtattg attgcattta aaacgttttc ttttttagca
    13801 attctttttt attcgtttaa tcacaatacg cttttcttct ttatcatgaa tggtttagtc
    13861 gtgattttat ccatttttac ttattttatt ttttcactca tttttagcca attgaaatgt
    13921 ccgctcttct ttcgattagt tcctgtcacc tgttttattt acagcttgtt ttcctttttt
    13981 gtccttgctt taatgccact gaccaaccct tcgacgatcc aagtcgcagg aaatctgttg
    14041 gatatgctct tcatcgtcag tctaggtgta tttatgtggc aaagaaaaaa caaacaaaat
    14101 aaaaagcatt ttgaagcctg actattacga cttcataaat gcttttttag ttttaaacac
    14161 ttcaatctaa aagaataacc caagattgga taaattatta atgactcgcc attcgtttct
    14221 tagtgattct ggattatcaa atggacttcc taatctaatc agctagttct tcccataaaa
    14281 tgccatactt gactgaatca taatattgat tatttaaaaa tctaactttt cttatcacta
    14341 cttcctttgt cattccacat ttctcaccat ttttttgcat tcctttgttt ccagaccatg
    14401 tagtgaatct aataggtggt agataggcaa aatactcaaa taattctttt aaccataaag
    14461 gaagagaaag gctcctcctg caagagtcag tataattttt gcttactgct ctcttaggtt
    14521 ttactcacta aaactgttcc atattctttg atataagaaa atgcatgcgg tataaatttc
    14581 ttgctcagct cagaaaagat ttgtcgttta agaaaggcca tttcctccat tgtcaatgaa
    14641 ggatccaatg ttggtaattc aatctcaaaa ttgttttttt cgacaatagg taattctaat
    14701 gtgaatgatt cttcttcctt tatagtattc gtcacaagta gagactgatg gaaaatacta
    14761 ggccggcgat ttttatattt attcttacgt atcctgtcaa cgataacttc tatttgatca
    14821 aaaaagtacg attcatttac gtctccaata agttcggcta attctttgaa tgccttcgtt
    14881 acaggaagct gattcttctg tacaaaaaag taattagcca aagtaagcgg gaagtgttct
    14941 atagaggaaa gtgtgataaa acggtacttc tcatttcctg cagttgtcct cagcaattct
    15001 gtctctcggc tgtttcttac tccataaaaa tacgcttctt tccgttcatc ttcgaaacaa
    15061 tacgcccaaa taacttctcc catcgctaat ttttgttcat caacagagag tctcttcaat
    15121 tgttcagcta tggtttcagc agccgaagtg gcttgttgca agtaatcttt aggatcaaat
    15181 attggaaagt tcaaatgata tcttcgttct tccctcttga ttaatcctgc atcgatcaat
    15241 aaatcaagaa aatgggaaaa tttattttgc gaaaattctt ttttcaattc tcttagaatc
    15301 gtttcttgtt ctcgatgttc atatagataa tcggtcaatg aagaaaaaag cggatcatcg
    15361 gtcagttttt gataaaagtt ttccttattt tttgaataat agttcatata tgttctcttt
    15421 tctatccgtt ttattttact taaaaggctt ttacgtaaaa aggaggaaga acaagagtca
    15481 taattgactg ttattctcct ccatttcttc ggcctttagt atgttctatg tttcttttta
    15541 tatcaatcgc ttatccattc attttgaatg cttcatacta ccatttgatt agctaaatac
    15601 agccgtcaat tgaggtacga cttgtttttt acgtgaaacg acacctttaa gcaaagcacg
    15661 gttgttggtc aaagttgttt ggaaagcttc ttctactttt tcttttcctt taccagcaac
    15721 aagtaattct gaatcactgt ctaagatgtt tgtgacaact aatacgaaca gatcgtagcc
    15781 atttgctttc atttcatctt ccattgctgc ttctagctct gcttgtcgat ccatcacttc
    15841 attaaggtcc actgtattga cttgagcgat acgaacgttg gaactgccca ttgggaaact
    15901 ttttgcatcc aaatcaagaa gaaccgcagc tgatttatca cttagatttg ttcctgcttt
    15961 caacatttca agtccataag tgtttagatc gacttcagcg attgctgcaa gttcttttgc
    16021 agctgcttca tcttcaggcg tacatgttgg tgatttgaac aacaatgtat ctgaaatgat
    16081 agctgagagc atgattcctg cgatttcttt aggaattgtt acttggtttt ctttatatag
    16141 ttttaaaata atcgtacttg tacatccaac tggttctgca cgatagtaca atggattagc
    16201 tgtttcaaag tttgcaatac gatggtggtc tactacagct aaaatattta cttcgctgat
    16261 atctgaaata ctttgttgga attcattatg atccacaagc atgacatctg cattttctgc
    16321 tttagctgac tctactactc gtggtgcaga tagctgaaag tggtctaatg cgtattgtgt
    16381 ttcttcatta ggtgtaccta gagcaactgc ttctgtttct ttacctaatt cattttgcaa
    16441 gtgtgaaaac gcaatggctg ccccgattgc atctgtatct ggattttggt gaccaaaaac
    16501 taaaattttt gacatgtcat tcgctccttt gtgatttctc ctatttaata atagcaaaaa
    16561 aacggaaaga agcaatactt atcttctttc cgatgcgacc tatcgcgtta aatattttgt
    16621 atactcttct gtatgaagca atcgtttagc attttcgaca cgttcttttg taggtggttc
    16681 gatcccttct aatggatatt tcaaaccaag tgtttcccac ttgtattttc ccatcgtatg
    16741 ataaggaaga atctctactc tgtctacatt tgacaaggtt tgaataaagt tgtctagtcg
    16801 gatcaaatat tcatcataat cacttcgctc aggaactagt acatggcgaa tccaaaccgg
    16861 tttgttgatt tttgacaaat attgagccat ttctaaaata ttttcattgt cccaatgcgt
    16921 tagtttttta tgctcttcat tatcgatgtg tttgatgtca aataacagta aatctgtata
    16981 cttcatcaat tcttgaaaac gtgaaaagaa aggttcttca tacgtaaaag gttttccgca
    17041 tgtatccaat gtagtatgca tcttccgctc ttttgctttt ttaaatagtt cgatcaaaaa
    17101 atcgatctgc aatagaggtt ctccaccact aacagtaata ccacctttat ctccccagta
    17161 aggtctgaag cgttctgctt tatctaaaag ttcatctgct gtgtattctt tccctccgcc
    17221 aatattccaa gtatctggat tgtgacaaaa ttggcaacgc atgcggcatc cttgcataaa
    17281 cacgacaaag cgcagtccag gtccgtctac tgaaccgaaa gtttcgatag aatgaacata
    17341 gccgattgtt ttttcttcca tttaagttca catcttttct ttgatttcat tttaagtaca
    17401 agttagctgt cgaagcgaag ctttctgaac aaaatttttc gcaattgccg cttcgttatg
    17461 tgtaaaattt acagggacgg aacatacaag tcctgcccct gtaaatcgtt tctttcaaat
    17521 aagcatactg attattcgat tttgatgcga tggctattca acgtcctttc gacgctaagt
    17581 cgaaaaactt ttttcacgaa ctttttacat tctgtcgtgt gaagttctca tcaagacatc
    17641 taattgttgt tctcttgtca agtcacggaa tttaactgca taaccagata cccggatcgt
    17701 caagttcgga tatttcattg gattttccat tgcatcacgc aataaatcat tactgaatac
    17761 attgacattc aaatgataag ctccttttga gaagtatcca tctaagacat tacgcaagtt
    17821 ttcgattctt gtatcttgtt cttttccaag acctgaagga ttgattgttt gggtatttga
    17881 aattccatcc aatgcacagc cgtaattcat tttagctgtt gagttcaggc tagctaataa
    17941 cccactttgt tccgcattgt aacttggatt tgctcctggc gcaagtggtt ttccagcttc
    18001 acggccatca ggagtatttc ctgtattttt accgtaaaca acatttgaag taatcgtcaa
    18061 taatgaagtt gttggttttg agttgcggta agttttatga cgtttgattt gtcccatgaa
    18121 gtattccaag atccatgaaa ctaattcatc tgcacggtca tcatcatttc cgtatttagg
    18181 gaagtcgcca tccacttcaa aatcaactgc tattcctttt tcattacgga ttgcttttac
    18241 ttttgcatat ttgatcgctg acaagctgtc tgccgcatga gagatcccag caatacctgt
    18301 agcaaatgtg cgttgcaagt cagaatccat caaagccagc tgagctgctt cataagaata
    18361 tttatcatgc atataatgaa tgatgttcaa cgtattgaca tatagttctg ctaaccaatc
    18421 catcatattc atgaagttat gtttcacttc ttcaaagtct agtatttctg atgtgattgg
    18481 acgatattct ggtccaactt gggcgccagt cacttcatcg actccgccat tgatggcata
    18541 taatagtgtt ttagccaagt tagcacgagc gccaaagaat tgcatgtctt ttccgacaac
    18601 tgttcctgat acacagcaag caatcgcaca atcatcagaa ccccattgtt cacgaagctg
    18661 attatcattt tcgaattgaa tcgaagaact ttcgatagcg attctgctag catatgttct
    18721 gaatccttct ggaaggtgtt cagaatacaa aacagtcaag tttggttctg gtgaaggtcc
    18781 catatttgtt aatgtatgaa gcagacggaa atcattcttt gtaactaatg aacgaccatc
    18841 taatcccata cctgcaatgg ataaagtagc ccagataggg aatcctgaga ataattggtt
    18901 atattcaggt gtacgcgcga atttgaccat acgtaatttc attactaagt ggtcgatcaa
    18961 ttcttgtgct tctttttctg tgattactcc attatccaaa tcacgttgga tatagatatc
    19021 aaggaatgct gagatacgtc cgattgacat cgcagcacca ttttgtgatt tgattgctgc
    19081 taaatatccg aagtatagcc attggacagc ttcttttgca tttgcagctg gtttagaaat
    19141 atcatagcca tatttcgcag ccatttcttt catttgcgct aatgcacgat attgttcagt
    19201 gatttcttca cgtaaacgaa tcacttcttc actcattgta tgataaccag tcatatcatg
    19261 atcttttttc ttttgttcca tcaaatagtc gattccatac aatgccacac gacgatagtc
    19321 accgatgata cgtccgcgac cgtaagcgtc tggaagccct gtaatgattt tgtttttacg
    19381 agcagcacgc atttcagcag tataagcgtc aaatacacct tgattatgtg ttttgcgcca
    19441 gtcagtgaaa atatgtgtca attcatcgtt tggtgtatag ccattgcttt ttagcgcatt
    19501 gttagccata ttgattccgc cgaacggcat gaatgcttgt ttcaaaggtt tgtctgtctg
    19561 tagaccgacg attttttcca aatctttatc caaatagcct gcatcgtgtg aagtaatagt
    19621 tgatacgatt tctgtgtcca tatcatagac accgttacgc tcgaattgga tatcatttaa
    19681 cttttgcaat tcatcccata atttttctgt tgcttctgtt gggccttcca aaaagctgtc
    19741 atcaccgcga tattcagtgt agttattttg aataaagtct ctagtgtcta cgccttcttt
    19801 ccatttggta cctttaaatc cattccattg ctccattgta tggacctcct aaatttctgt
    19861 tttatgtaac agtttttacg tgattagtat aacacagcac cctatctttg caagggtttt
    19921 cttgtttttt atttaacaat ttttatgttt tatttacata tatttaaatc aacgttgaca
    19981 taccaacatt taagcattgt gaacactttc atcttttttt gcaaacgtat aaggatttat
    20041 taaaaatgaa tgaaaaagag acgccacctg tattaataca gatggcgtct cttcattaaa
    20101 atactacaac agttacgact cgatgaaaat ctcaggagca tcgataactt cgatgacttc
    20161 tccacctttt ttctcatcca tcgcaaatga tccattcgat gttcgatcac ctatagggaa
    20221 atcagttggg tcaatcgtta actgctgccc tttttgattc atcaaggtta tttcttttga
    20281 tcttccttcc gacatataga taatacggtg cggatttttt ttcagctcac gcatgaccgt
    20341 cactccccgc ttcgcacgtg aagtttggct gatttcttga gcaagcatgc gtttaacagc
    20401 tcctcgctga gtaacgatta cgatcggcgt atcaccttct gctaacacaa gcagcccgtt
    20461 gataatccta tctccatctt tcaaattcat agacttcact ccagctgcct ttgctccaac
    20521 aacgggaaca tctgttaaag gatagcgcaa acccattcct tgatgcgtta ctaagaaaac
    20581 atctaagcct ggctgatctt ctttcagata cacagcaatc agttcatctt cttccgcctt
    20641 tagcttcata cagctgagcg gacggctctt ataggtgcgc catggttcga actctgtcat
    20701 tcgtgtttgc ttgatcaatc cattcttgct gatgaataca aatgttttct ctgcttgaat
    20761 tttttgatat gggaaaacag ctaaaatcga ttcgtctaca gacagattgg agattgtttg
    20821 agaaatgtgc tcaccagcat ctttccattt caaatcgggt agttcatgga cagggcggta
    20881 gatcacattt gctttatttg tgatcagaag aacatggtcc aatgtactca attcacctga
    20941 gtatagcaag tagtcgcctt ctcgcatccc gatttcttct ggtttggaag cactataaga
    21001 acgaaggctt gttcgcttca catagccttc tcgcgtcaca ctgacaatta cgtcttcttg
    21061 tgccactaag acttgcgtat caattttgat ttcttcgatt tcgtcttcga ttgtcgttag
    21121 acgagcggaa gaataatttt ttttcacttc tcgcaattct tttttcataa cagagaaaag
    21181 ctctttgtca tttgaaagga ttttattcaa ctctgtgatt tgcgcaatca agctttcgga
    21241 ttccttttga agctctgtga tatccgtgtt cgtcaaacgg tataattgca atgtgacaat
    21301 tgcttctgct tgttcttctg taaattgaaa gacgtcgact aaattctttt tggcgtcttt
    21361 tttgtcttta ctttcacgaa tcgttgcgat tacttcatcc agaatcgata aagctttcat
    21421 caatccttct acgatatgct gtcttttttg agctttggct aaatcgaatt gactacgttt
    21481 tgttatgact tgctttcgat gctcgatata acttcttaaa atgtctttca gtccaacttg
    21541 atgcggagtc atatggtcga tagcgaccat attgaaattg taattgatct gtagctcagt
    21601 gtttttgaac aaataattca aaattccttg agcattggcg tcttttttca attcgacgac
    21661 aatttgcaga cctgttctat cactttcatc tcgtacttca gctattccat cgattttctt
    21721 attcaaacgg atctcatcca tttttttcac caaggtcgct ttatttactt catatgggat
    21781 ttctgtgatc acgatttgct gtttattacc cttcattgcc tctatctttg ttttcgaacg
    21841 aagaataact tttcctcgtc ctgtttcata agcttttttg atttcatctt ttccttgcaa
    21901 gatccctcct gttggaaagt caggtccagg aatatattcc atcaattttt caaggctcgc
    21961 ttgtggatga tcgatcatat agattgtgcc atcgatcact tcagctaagt tatgagtcgg
    22021 gatttctgtt gcatatccag cagatatacc tgtcgatcca ttgacgagaa ggtttgggta
    22081 tcgagctgga aggactgttg gttctttttc tgtatcatca aaattccaca cgagatcgac
    22141 tgtttctttc tcgatatctg ctagcatctc tccacttaac ttggataatc tggcttcagt
    22201 ataacgcatc gcagcaggtg gatcaccgtc catactcccg ttattcccgt gcatttcgat
    22261 cagtacttcc cgcaacttcc agtcttggct catgcggacc atcgcttcat aaatactgat
    22321 gtcaccatga ggatgataat tccccatgat atttccgaca gattttgctg atttacggaa
    22381 tcctttgtca tacgtattgc catctttgtt catggcaaat aatatccggc gttgcactgg
    22441 cttcaatcca tcacggatat caggcagtgc acgttcttgg ataatatatt tggaataacg
    22501 tccgaagcgg tcacccatca cttcttctaa agttaattct tgtacttctt gtcgattttc
    22561 catcaggtga cctcctattc tacttcaaat aactgattgt tttcattttt atctgctcgt
    22621 tcttcatcta ataaatcatt agaaactgaa ggagagattt cagtatcctc ttttttatct
    22681 aagatactgc catcttcttc gagcgtaaat tgcacgtgat tttcgatcca ttttcttcga
    22741 ggttctactt tgtcacccat cagtgtggtt actcgacgtt cagcttgcgc agcatcatcg
    22801 atacggacgc ggatcaacgt acgggaagtc ggatccatcg ttgtttccca caattgttcc
    22861 gcattcatct ctccaagtcc tttatatcgc tgcagcatat atcctttgcc gactttttta
    22921 atcattgctg ccaattcgtc atctgtccac gcatattcaa tgacttgctt ctttccttgt
    22981 cctttggata ctttatataa aggcggtaac gcgatatata ctttcccagc ttcaatcagc
    23041 ggtttcatat aacgataaaa gaaagtaagc agtaatactt gaatatgggc gccgtctgta
    23101 tccgcatcgg tcatgatgat tactttgtcg taattacagt cttcgataga aaactcagga
    23161 ccgactcctg caccaatcgt atagatcatc gtattgattt cttcattttt caagatatct
    23221 tgcattttag ctttttcggt attgatgact tttcctcgta aaggtagaat tgcttggaac
    23281 tttctgtctc ttccttgttt agcagatccg ccagcagaat ccccttcgac taaatacaat
    23341 tcatttttct tagggtttcg ggattgtgcg ggtgtcaatt ttcctgaaag aagagattcg
    23401 ccttttttac gcttcttccc atttcggctt tcttctctgg ctttacgtgc tgcttctctc
    23461 gcttctctgg ctttgattgc tttacggacc aacatctggc tcatttcgct attttcctgc
    23521 aaataaaagc ccatttgttc actgatgacg ttatctacta cggtacgagc aactggcgta
    23581 ccaagttttt cttttgtttg cccttcaaat tgcagaagat tttcaggtac acggatagaa
    23641 agtacagcag ctaacccttc tctgaaatca ctaccttcca gattcttgtc ccgttctttc
    23701 agcaaaccaa cttttctcgc atattcatta taagatttcg tcatcgccgc tttcatacca
    23761 gcttcatggg ttcccccatc ttttgtccga acgttattga caaaagataa aacattttct
    23821 gaataaccgt cattgtattg ataagcgacc tctacttcga taccttcttt ttctcctgaa
    23881 aaataaacaa ctggtgtcaa tgtatctttt tcttcattca gataatcaac aaattctttg
    23941 attccttctt cgtaatgaaa aatttccttg actggttctt ctccacgaag atcagaaaga
    24001 gagattttaa cgccttttag aagaaaggca gattctctta accgttcggc taaaatttca
    24061 tatgaaaatt tcgttgtact gaatattgta tcatctggta aaaaatggac agtcgtcccg
    24121 tttgcttttt ttgtttttcc tatctttttc aaagtaccgt caggtttacc gccgttttta
    24181 aatttctgct gatactctac gccatctcta acgatcgtta caattagcca tttcgataag
    24241 gcatttacca cactggctcc tacaccgtgc agtccaccag aagttttgta ccctccttga
    24301 ccaaactttc cgccagcatg cagcacagta aaaatcactt caactgttgg tattccggaa
    24361 gcatgcattc ctacaggcat cccacgtccg ctatctgcaa cagttatact attgtcttca
    24421 tggatggtca catcaatctc actgccataa cctgataatg cttcgtcaac tgcattatcg
    24481 acgatttcat agactaaatg atgcaagcct cggctgtcag tggatccaat gtacatccct
    24541 ggtctttttc taactgcctc taatccttcc aatacttgga tggacgagtc attgtattcg
    24601 ttgtttactt tttttgccaa ggcaaacgct ccttcaataa tactttgcgg caaaaccgca
    24661 ccacgattat catactagaa aaggtcgtga aaaaaaagag ggtagacgag aaatcaattt
    24721 taattatctc ctaaccgctt tttcgacatt cccctctatc gatcatctct tctttgtggt
    24781 catttttatt tttggttttc tttcaactta ccaagttcaa tcttaataca acgatccatt
    24841 acgatatctg tacgtcctgc ttttcttagc atctcagctg cttctttgtt ttcaatccct
    24901 aattgtgccc agaacacttt agcatcagtt ttcaaaaaat cacctgctat ttcaggtaaa
    24961 aattcactcc gtctaaatac atctacgata tcgattggat catcgatttc tgtcaaattc
    25021 gcatagactt tctcgcctag aatttcttca ccagccaata atggatttac tggtatgatt
    25081 ttatatccat tgtcttgcaa tacctgtgca accatgtaac ttgttcgttc tggtttattg
    25141 ctcaagccta cgacggcaat attttttgct tcttccaaat agttgaaaat cgtttcttgt
    25201 gttggatttt ttacagacat ttctgccacc ccttgctttt ctttttattc catctattat
    25261 acttgtatct ttcatttttt caattgttcc tgttacctat tcatgctaaa ataaaggata
    25321 gttttcaact tgaaagaggg taaaaaatga aattgatctt attacttatt ttagcatatc
    25381 ttttaggttc tattccttcc ggtgtctgga ttggcaaatt gtttttcaaa aaagatatcc
    25441 gacaacacgg gagcggtaat actggaacga ccaatacatt tcgtgtatta ggcaaaacag
    25501 ccgggattgt tgtcctgctt atggatattt taaaaggtac attggctact tgtttgccga
    25561 tgatcttcca cctttctggg attaaccctc tttggtttgg ggtatgcgcc attcttggcc
    25621 atacatttcc gatttttgct gggttcaaag gaggaaaagc tgttgcgaca agtgcaggaa
    25681 tgcttttagg atttaatcct gtattttttg tttattcttg tatcatcttt atcgttagtt
    25741 tattttgtac aagtatggtg agtttgagca gtatgatcag tgcagtattg atcactttat
    25801 ctacgatcgt ccttccttat gtagctcctg tgattttggc taagcccaat tggttactga
    25861 cgatcattgc ctttttagtt tcttccttta tcttttatcg gcataaagac aatatcaagc
    25921 gtatcagaaa ccatactgaa agtcgaatcc cgtttggttt gaatagcagc aagaaaaaat
    25981 cctgatactt tttcattcca aagagataaa acgggagtgt gacaaatcga tgtcacactc
    26041 ccttattact tacaggatag cttttttaca caccttggta aacggtgttc cctgctaact
    26101 tctcggtcac aacctcttac ttcactgtga tggaatattt tgtcttgaag atttcatggg
    26161 cacctagttg attgatccct actttttcca tcaagtttcc actactgttc accgtgtcag
    26221 cgattccgca ccacggttcg atacaaacga aaggcgcttc ttttggataa ggagaccaga
    26281 tccctacata aggcatatct ttatagctta aagttacgct atgggaagat ttttcacttc
    26341 gaatggcgta cgcatttaga ccccttgttt caaaaaccaa ggcatcttgc tcaaaaagtt
    26401 cacgattcaa agccagattc gtatttgtct gacctaacgt cttttgatcc atatcgatga
    26461 atgggccttt caatggtagg cgtaatcttg atttcaatgg agaaaatgcc agatagaaat
    26521 cttcaaatga caatccttct tcaagaggta cattgaaagc aggatgtcca ccgatagaaa
    26581 agaacatttc tttttcaccg gtatttgcca cttgataatg aaccgtgatg ccgtctcctc
    26641 ctaattcata gctgatcact aattcaaaat caaatggata cttttctaat gtctccggcg
    26701 tactccttaa gatgaaacta gccatttctt gtccatgttc aatgacttca aaatccatat
    26761 cccgagcaaa tccgtgttgc cccatttgat atgttttccc ttgataaaca tactgatcat
    26821 cttttaaacg tccaacaaaa gggaataaaa ccggtgcatg tctgccccaa tacgctggat
    26881 caccttgcca gatatactct aaaccatgtt cttttgattt cagactgatc aattccgcac
    26941 cgtgttcagc gatttcggcg atcagctggt cattttgaat aataacagtc attgccattc
    27001 ctccaacttc gacttacttt ttaaaatggg aaggctggaa caaacatttc tatctgcccc
    27061 agtcccctta cttctaataa ctgtgttttg ctaactcgtc tttaaaacgg gaattcaata
    27121 cttttaaata agttcccttc atgcctaacg aacgagattc aatgattcca gctgattcca
    27181 attttcgtaa agcattgacg atcacagaac gagtgatgcc gatactatcg gcaatattag
    27241 aagcagtcag acgaccttca tctccatcca atgcttcaaa gatagcttgt acagccttca
    27301 attcgctata agataatgtg ttgattgcca tttggacagc cgttgcactc cgtacatctg
    27361 cttcgatgct tcgagacttc tgataaagga tctgcatacc gacaaccgta gctccatatt
    27421 ctgctaagac tagatcgtca tctgcaaacg attgttccat acgagataag ataatcgtac
    27481 ccaaacgttc gccagctcca aagatcggaa cgacagtcgt cagaccaaat ggatatttct
    27541 ctcttgactc taccggaaat gcagtaatat cactagtaat tgggatatta gcttcagttt
    27601 tcatcaactg tgccactgta tcagtataag attcaggaaa ttgtttctca acaaacattg
    27661 ttttgattcg ttcattgttc acatcgtgac gttcattata acctagtaat actccgtcac
    27721 ttcctatgat ataggtgttg ctgtcaagaa taccacctag tgtgacagcc attttatcgt
    27781 aaggcaaatc tgcttgcatg tcaaaagtat tcttttgctg caaaagtgtg tttatcttgc
    27841 gggttttcgt tagcaagtct gtcattgtcg tcctccgatt ttttataaaa tatagcgact
    27901 taaatcttca tttgccgcaa ttgagccaag tttgtcatcc acatatgctt ctgtgatcgt
    27961 tatttctccc atttgcatat ctggtgcttc aaataataga tcttctagta gtttttccaa
    28021 aatggtatgc agtctgcgtg cgccgatatt atctgtgtca cggttgacat cgaaagcgat
    28081 ttgagcgatc cgttcaattg cttcttttgt aaacgtaact gacacatttt ctgtaccgat
    28141 caacgcgacg tattgtttta ctaaagcatt atttggttcg gtcagaatct tcacaaaatc
    28201 ttcagctgtc aaatcatcta attctacccg tatcgggaag cgtccttgaa gttctggaat
    28261 tagatcactt ggtttagaca aatggaaagc tcctgaagca atgaatagga cgtgatctgt
    28321 ttggatgatc ccgtattttg tgtttacttg tgaaccttcg acaattggca atatgtctct
    28381 ttggacgcct tctctggata cttctccaga ttgctgtgat ttagaagtga tcttatcgat
    28441 ttcatcgata aaaataattc cactttcttc cgctaatttg attgcctcac tatggatatc
    28501 agcatccttg actaattttg ctgattcttc cttgatcaat aactctaaag cttctttgac
    28561 tgttaccgtc cgttccactt ttttcttcgg tgtcaaagca cctagagttt catttaggtc
    28621 gatccccatt tgctccaatc cattgttcat cattggtgca ggtttctttt ggtcttcaac
    28681 ttcaatggtt acttcacgac tatccagtaa acccttttgt agttgttcca agactgtacg
    28741 gcgattgatt cgaatatctt ctgtcacttc ttcttgcggt tcagcggtat tttgctgact
    28801 agcattaaaa agattcatca tttgttcaaa ttgattagtg gattgtttct gttctttttt
    28861 gataccaggt accaagattt ttaccaaacg tttttctgca ttttttttag cacttgtgta
    28921 tacacggctg tactgctctt tttctacgat ttggatcgca ttttctacta aatcccgaac
    28981 cattgattct acatctcttc cgacataacc gacttcagta aattttgttg cttcgacttt
    29041 gacaaatggt gcattgacga tttttgccaa acgtcgtgcg atttctgttt taccgacccc
    29101 tgtaggtccg atcatcagca tattttttgg tgtaatatct tgttgcattt tttcatctaa
    29161 ctgcaaacgg cgatagcggt tacgcaaagc aacggcaaca gatttttttg ctgcgtgctg
    29221 tcctacgata tattcatcta attcacttac gatttgtctt ggtgtttgtt ttaattcata
    29281 catatctact cacctcttac agttcttcta cgataatatt atgattagta aagatacaga
    29341 tatctgcggc aatatttaac gcattttctg caatttcttt cgcactcatg tcgttttgag
    29401 catagttttt cattgctcgg gctgcagcca acgcaaaatt ccctcctgat ccgatagcta
    29461 agataccatc atctggtgtg ataacttctc ctgtacctga aacaagaagc atttctttat
    29521 cattcattac gatcagcatc gcttcaagtt tttgcataga ttgctgtgtc cgccattctt
    29581 gagctaattc gacagctgcg cgttgtagat tcccgttata ttcgtttagt ttgccttcaa
    29641 atttttcttc taaagtaaac gcatctgcaa cacttccggc gaaacctaca acaacttctc
    29701 cattgtagat acgtcgtact ttctttgcag tgcctttcat gacaacagat tcacccattg
    29761 ttacttggcc atctccagcc atagcaaatt tcccgtcttt ttcgacggca cagatagtgg
    29821 ttgaatgaaa tggtgattcg accatgtttg tttcctccta aatttgttct tttccttatt
    29881 tttacgctct tggatggaaa gaacgatagt ttttttgtaa actttctttt gttacatggg
    29941 catagatctg ggtagtcgat aaattggcat gtcctagcaa ttcttggact gtccgcaaat
    30001 ctgccccatt atttaataaa tgagtagcaa atgtatggcg cagcatgtga ggatggatat
    30061 cactatccaa actgcttttt ttgatcattt gattcaagac atattcaatt ccagtaggcg
    30121 tgattggttt tccatgatga ttcacaaaaa cgatatcatg ctcttcgtga tattttgtca
    30181 tcaatacctg gcggccttcc ctgaaatatt cttgcagagc atcttgagca aaagaaccta
    30241 gaggagcata tctctctttg ttccctttac catggatcaa catgacctct gaatcaaaat
    30301 caatgtctga taccgacaaa ctgctacact cacttaaacg gatgcctgac ccgtaaagga
    30361 cttccagtaa agcgcggttc ctcaaatcca aaggactatc tcctgctacg ctgtcaaaaa
    30421 gtgcttgcat ttcattttca taaaaaaaac gtggcagtct caaatttttc tttttgagat
    30481 gaacgtaaga aaatggattt tcttttatca cttcttcttt gagaagatac tgataaaacg
    30541 aacgtaggct ggctatcttg cgactgatag aatttctgct atagctagga cgatgatcag
    30601 ctaatgcact caaatagaca cgaaccgtaa aatattccgc cttcagcaga tcagcgtctc
    30661 cagattcctc caaaaaatgt ttgaaatgga gaatgtcttc ttcatatgct tctttcgttt
    30721 tttctgaata tcctctttcg acaatcaaat aacgcaaaaa tttttgttcc cacgtggctt
    30781 ctgtcatttt ctcaccttcc ttttgtccca gagaataatt tagcacagcg tttataaaaa
    30841 gacaaataaa ttgtcagaat ttaaccaata tttctaagtt tgttcacaat tggcgcaatt
    30901 cctcacattt tgtttgagaa attcttaaga aaaacgcaag aaaaagagcg agactatccg
    30961 tctcaccctc ttcatggagt ttccttactc atttgggatt gcagtttttt ctaattctgt
    31021 ttttattgcc tcattagctt ttaaagctcg ttgtgcaatt gcttcatatc ttgctttttt
    31081 gtctcgaatg cgctctggca gttcaggaaa cagaccatag ttggcattca tcggttggaa
    31141 atgttttcct tccgcatgag taatgtagta agccatactt ccaatagctg tttcttgtgg
    31201 aaactcgact ggttccattt cttttgctaa gcgtgcggcg ttgattccag caagtagtcc
    31261 gctcgctgca ctttcaacat agccttctac accagtcatc tgacctgcaa agaacagatc
    31321 ttcgcgtttc gttgattggt aagtcggttt cagcaattct ggcgaattca taaagctgtt
    31381 tcggtgcatc acaccatagc gaacgaattc agcattttct aacccaggaa tcatccggaa
    31441 aacacgtttt tgctcgcccc atttcaagtg agtctgaaag cccacgatgt tgtataaaga
    31501 agctgcagca ttgtcttgac gcagctggat aacagcataa ggacgtttgc cagttttagg
    31561 atcttccaat ccaactggtt tcataggtcc gaaaagcatc gttttgaatc ctcgctgtgc
    31621 cattacttca attggcatac atccttcaaa atatttttct ttctcaaaag atttaagttc
    31681 tgccacttcg gcattgatta gtgcctcatg gaaagctttg aattcctctt ctgtcatcgg
    31741 acagttcaag taagctgctt ctcctttgtc atagcgggac ttcaaatata ctttatccat
    31801 atcgatcgta gctttgtcta cgattggtgc agctgcatca tagaaataaa aaccatctga
    31861 accattgaat gctttgatgc tttctgctaa tggatgagaa gtcaaaggtc ctgttgctac
    31921 tacggtgatt ccttccggta tttcagtaat ttcttcgttt atcactgtta ctaatggatg
    31981 ctctttgact tttcgggtaa ttgtttcaga aaaagaatcg cggtcaacag ctaaggcacc
    32041 accagctggc actgctgttt catctgccga agtgattact accgaattca atcggcgcat
    32101 ttcttctttc aataacccta ctgcattagc caaactgttt cctcttaatg aattggaaca
    32161 tactagttca gcaaaattac ttgtgtgatg cgcctcagtc gatttgactg gacgcatttc
    32221 atataaacgg acagggactc ctgcttgtgc gatctgccaa gcagcttcac ttccggcaag
    32281 ccctgctcca acaacattta ccattttcaa tgaaagaacc tcttttctat tatttttgga
    32341 tgtcttcttc gtaatctcca tttacacaga ctacttgttt accgcctttg actttcttct
    32401 cgaccagata tccgtcacat tttggacaat ttctgcccac tggtttatcc caagaagtga
    32461 attcacattc tgggaaacgg gaacaaccat agaatagtct gtttttctta gattttcgtt
    32521 caatgacttg tccttcatga catactgggc aagtcacacc gatttctttt acgattggtt
    32581 tcgtattccg acaatcagga aaattactgc aagcataaaa cttcccatat ttccctaatt
    32641 ttatcaccat cggatgtcca cagacatcac aatcgaatcc tgctggttca tctttgattt
    32701 gaattttttc gattttttct tccgcattcg tcagttcttt ttcaaacggt ttatagaaac
    32761 gatcaaccac tttgacccac gcttccgtgc cttcttcaat tttatccaaa tctccttcca
    32821 tttctgctgt gaaatggata tcgacgattt gagggaagaa ttcacagatt aatgaattga
    32881 caatttctcc tagttcagtc ggctcaaatc ttttttgtgt caattttaca tagtagcgtc
    32941 tttggatcgt atcaagtgtt ggtgcataag tggaaggtcg ccctaccccg ttttcttcta
    33001 gtgcacgaat caacgtagcc tcactaaaac gtgctggtgg ttgagtaaaa tgttgttttg
    33061 gttcaatatc aacagattgg actacatcgc cttcttcaag ttctggaaga atattttctt
    33121 tctcttcttt gccgtcatct ctaccttcca catacacttg catgaatcct ttgaatttga
    33181 tttttgaacc gttcgcaatg aagatgacac cattttgttc taatgtcact ttcattgtat
    33241 ctaaaatagc tggtgtcatc tgactagcca caaaacgtga ccagatcaat gtataaagtt
    33301 tcaattgatc tttatctaaa tattgtttga gttcatctgg tgtacgaagc acactcgttg
    33361 gacgcacagc ttcatgggca tcttgtgcgc cttgagcatt tttgatcttt cggtgatcat
    33421 gtctagaaaa ttcttttcca tacgtatctt caataaatgc tgcggcctct gcttttgctg
    33481 tatcggcaat ccgggtagaa tcagtacgca tgtatgtaat caagccgact gttccttgtt
    33541 tacccaaagt gattccttca tataattgct gtgctaccat catggttttt cttgttcgaa
    33601 agtttaactt acgggcagct tcttgttgca ggctacttgt agtgaaagga ttcgcagggt
    33661 ttcttttgcg ctctttcttt tctacttttt taacttcgaa gtctgttcca tcaattctag
    33721 cagtgacttc ttttacactt tgtgcatctg gtaatttctt tttcttaccg tcgattcccc
    33781 agaaatttgc tttgaatttc ttgcgagctt ttttaaaatt accgtcgatg ctccaatatt
    33841 cttctggaac aaattctcgg atctcttttt cacggtcaat aataattttt aaagcgacag
    33901 attggacacg tcctgcactt aaccctttct tgaccttacg ccagagaata ggactgatcg
    33961 aataaccaac gattctgtct aaggtacgac gagcttgctg tgcatctact aaatctacat
    34021 cgatcgttct tggttcctta aaagctgctt tgactgcgtc ttttgtgatt tcattgaaga
    34081 ccacccgatt tttttctttc agatccaacc caagtaggta cgctaaatgc caagcaatcg
    34141 cttctccttc tctatccggg tcacttgcca agtaaacttt ttgagctttt tttgctgcgg
    34201 ctttcaggct tttgatgaca tcgccttttc cgcgtataga aatataatgg ggttcataat
    34261 tgttttcaaa atcgataccc attttacttt tcggtaaatc tcttatatgg ccaacactgg
    34321 ccattacttt atagtttcgt ccaagatatt tctcaattgt cttggctttt gcaggtgatt
    34381 ctacaatcac taaatattta tacgccatta ctgaatggac tcctttccat tgtcgtgttc
    34441 ctactattaa aagaggattc atacaaatcg tagctaatca tatccattca gaaaacgttt
    34501 gtcaagaaaa gcaaatgaaa agtatggtgt tattctttaa attctgccaa gatatcttca
    34561 cccgaaaccg tgcaaactgc accgtcttgg atcaaatgat gacatccggt agaatgttct
    34621 gttaaaatat ttcctggaac agaaaaaact gttcttccaa gatccaatgc ttgctgtgct
    34681 gttatcagag agccgctttt tttcttggct tcaaagacac atgttccttt agacaaagct
    34741 gcgataatcc gatttctcat tggaaaacaa tgctttttcg ggccggattg aggaggatat
    34801 tcactcaaaa gaagatgatc atttgcaatc acctcttgca agtcacgatt ttcagcagga
    34861 tagacttgct ctatccctgt tccaatgact gcgattgtcc gtccaccatg agagattgct
    34921 gcttggtgac cgtatgtatc tatccctttc gcgcagccac tgacgatcac atatccagct
    34981 tctatcactg gttttagtaa ataataaact gtttttttgg ctaaagcaga agtgtgtctt
    35041 ccaccaacaa cgcttaacat gttacaagaa agtaaagata gatcaccatt ataaaacagt
    35101 acaattggcg gataggtcaa gtgaagcagc tgagggggat atttgggatc aaagcaagtg
    35161 ataaacgact gtttcgattg gattttgccc cagttagcgt gaatttcctg ccaacttttg
    35221 cgaaacagct cccggtgttt ggttatttta cctatcttaa tgatgtcttc aaatccgatt
    35281 tctttataag gatactgcat catccagtta gcaagtgccc attttccttg actactgatt
    35341 ccttttgtat aagcaagttt caataaattt tcttctattt gatacatcat aaaaccgcct
    35401 ttcgtctctc tttctaataa gatacgtaaa agcggctgtt ttttattgta aatatttttt
    35461 tacaggtgca aaacttttac gatggattgg cgtaattcct tgtcgttcaa gtccttctaa
    35521 gtgttccttt gttccataac ctgcattatg cgagaaacca tatccaggat aaagcacgtc
    35581 atattctttc atcaattggt ctcgatatac tttagcaatg atacttgcag cagcaatcga
    35641 cacagatcgt acatcccctt tgattatttt ttcctgctga ataggcaaat ccaaggtcat
    35701 cgcatcgatc aacaaatagc ttggtacaat ggacaatttt tctactgctt ggatcatcgc
    35761 taatttactt gcttcataaa tattcacatc atcgattgtc tgctgatcaa cgatcccgat
    35821 cccgattgcc agggcttttt cttgaacttg ttgataaaga agttctcgct ttttctctga
    35881 taattgtttg gagtcattca gccctaatat gatctcattt ttcggcaaga taactgcagc
    35941 tgccacgaca ggtccagcta atggtcctct tcctacttca tcaatgccgg caatccattg
    36001 gtgaccttgt gcgtaccctt gcttttcaaa gcaaaacatt tcttcatatt tttccttaat
    36061 taatgcttcc tttttcaatc gtcgttcaaa agaagccagt gcttgctgca cgcctttgcg
    36121 tggatcattt cttaatgatt ctagtgtagg atcatctatt ctctgtatgc ttttcaatcg
    36181 ttctttgata ctttggatgg attcagtcat cacttttttg ctccatttct tcgcaacgat
    36241 ccagtgtgta tcgtccaagt tttccttgac gaatatcatg cacgactaat tcgctgccac
    36301 gatcatagtc ttctttatac ccacgttttg ctgtaatatc catcagtaat tccggtgcca
    36361 atttttcttc ttgctcgatt gataaaccat aacgatcgct gattcttcct gaataatatc
    36421 gggcaaaaaa gtctaatccg taaatcgcta aatcatctaa atggacaagc tggtctttga
    36481 tcgcgcctgt cagcgctagt tttttgccga tttcttcatc ttcaaatttg ggccataaaa
    36541 tccctggtgt gtctaacaat tccaactcat tacctaaacg aagccactgc tgaccttttg
    36601 ttacgccagg cttatttcct gtctgtgcaa ttttcttgcc tactagtcga ttcatcaacg
    36661 tagatttccc aacatttgga atacctaaga ccattgcccg aatagcgcga ggcttgatcc
    36721 cccgagcagc atctcttgcc cgtttttctt tcaatgcttc tttagccgca ggtactagac
    36781 ctttaattcc tttactttct tgtgccgtga tagctaatgc aagatggcct tgtttacgaa
    36841 aatattcttg ccacagcttt gtctgttgtg gatctgccag atccgcttta ttcaataaaa
    36901 caaggcgagg tttttgctga atgatctgat ctagcattgg attacgagaa gataaaggta
    36961 atcgtgcgtc taccaattca aatacgatgt ccacatattt cattttttca gaaacttctc
    37021 gtcgggcttt tgccatatgt cccggaaacc attggatggt cattgttctc tccattcctt
    37081 tcataccgga atattccccg gctttacttg tttttttctt tttcaatata aattcacttt
    37141 tttatt
//
LOCUS       DACDAF010000017        36568 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.017, whole genome shotgun sequence.
ACCESSION   DACDAF010000017 DACDAF010000000
VERSION     DACDAF010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36568
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.017"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(25..1521)
                     /gene="lysS"
                     /locus_tag="IVZ69_000815"
     CDS             complement(25..1521)
                     /gene="lysS"
                     /locus_tag="IVZ69_000815"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HAP8182923.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="IVZ69_000816"
     CDS             complement(1632..2636)
                     /gene="dusB"
                     /locus_tag="IVZ69_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HAP8182924.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="IVZ69_000817"
     CDS             complement(2637..3524)
                     /gene="hslO"
                     /locus_tag="IVZ69_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HAP8182925.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3741..5852)
                     /gene="hflB"
                     /locus_tag="IVZ69_000818"
     CDS             complement(3741..5852)
                     /gene="hflB"
                     /locus_tag="IVZ69_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HAP8182926.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="IVZ69_000819"
     CDS             complement(5942..6487)
                     /gene="hpt"
                     /locus_tag="IVZ69_000819"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HAP8182927.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="IVZ69_000820"
     CDS             complement(6487..7932)
                     /gene="tilS"
                     /locus_tag="IVZ69_000820"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HAP8182928.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8052..8522)
                     /locus_tag="IVZ69_000821"
     CDS             complement(8052..8522)
                     /locus_tag="IVZ69_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HAP8182929.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8568..8993)
                     /locus_tag="IVZ69_000822"
     CDS             complement(8568..8993)
                     /locus_tag="IVZ69_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HAP8182930.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9060..9329)
                     /locus_tag="IVZ69_000823"
     CDS             complement(9060..9329)
                     /locus_tag="IVZ69_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HAP8182931.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9340..10935)
                     /locus_tag="IVZ69_000824"
     CDS             complement(9340..10935)
                     /locus_tag="IVZ69_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP8182932.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="IVZ69_000825"
     CDS             complement(10950..14471)
                     /gene="mfd"
                     /locus_tag="IVZ69_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HAP8182933.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14488..15048)
                     /locus_tag="IVZ69_000826"
     CDS             complement(14488..15048)
                     /locus_tag="IVZ69_000826"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HAP8182934.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15401..16375
                     /locus_tag="IVZ69_000827"
     CDS             15401..16375
                     /locus_tag="IVZ69_000827"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP8182935.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16545..17945
                     /locus_tag="IVZ69_000828"
     CDS             16545..17945
                     /locus_tag="IVZ69_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase family protein"
                     /protein_id="HAP8182936.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18023..18745)
                     /locus_tag="IVZ69_000829"
     CDS             complement(18023..18745)
                     /locus_tag="IVZ69_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP8182937.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18824..19330)
                     /locus_tag="IVZ69_000830"
     CDS             complement(18824..19330)
                     /locus_tag="IVZ69_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP8182938.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19453..21252
                     /locus_tag="IVZ69_000831"
     CDS             19453..21252
                     /locus_tag="IVZ69_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HAP8182939.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21320..22894)
                     /locus_tag="IVZ69_000832"
     CDS             complement(21320..22894)
                     /locus_tag="IVZ69_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182940.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="IVZ69_000833"
     CDS             complement(23149..23658)
                     /gene="mreD"
                     /locus_tag="IVZ69_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HAP8182941.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="IVZ69_000834"
     CDS             complement(23662..24516)
                     /gene="mreC"
                     /locus_tag="IVZ69_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HAP8182942.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24671..25309)
                     /locus_tag="IVZ69_000835"
     CDS             complement(24671..25309)
                     /locus_tag="IVZ69_000835"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HAP8182943.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25310..25960)
                     /locus_tag="IVZ69_000836"
     CDS             complement(25310..25960)
                     /locus_tag="IVZ69_000836"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAP8182944.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="IVZ69_000837"
     CDS             complement(25973..26872)
                     /gene="rsgA"
                     /locus_tag="IVZ69_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HAP8182945.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="IVZ69_000838"
     CDS             complement(27037..29106)
                     /gene="pknB"
                     /locus_tag="IVZ69_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HAP8182946.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29103..29843)
                     /locus_tag="IVZ69_000839"
     CDS             complement(29103..29843)
                     /locus_tag="IVZ69_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HAP8182947.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="IVZ69_000840"
     CDS             complement(29856..31214)
                     /gene="rsmB"
                     /locus_tag="IVZ69_000840"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HAP8182948.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31214..32152)
                     /locus_tag="IVZ69_000841"
     CDS             complement(31214..32152)
                     /locus_tag="IVZ69_000841"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HAP8182949.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32145..32636)
                     /gene="def"
                     /locus_tag="IVZ69_000842"
     CDS             complement(32145..32636)
                     /gene="def"
                     /locus_tag="IVZ69_000842"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP8182950.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32651..35059)
                     /gene="priA"
                     /locus_tag="IVZ69_000843"
     CDS             complement(32651..35059)
                     /gene="priA"
                     /locus_tag="IVZ69_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HAP8182951.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35312..35617)
                     /locus_tag="IVZ69_000844"
     CDS             complement(35312..35617)
                     /locus_tag="IVZ69_000844"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP8182952.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="IVZ69_000845"
     CDS             complement(35622..36236)
                     /gene="gmk"
                     /locus_tag="IVZ69_000845"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HAP8182953.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9885 a         7989 c         6706 g        11988 t
ORIGIN      
        1 attccttaga cagcttttat tcgattatct cattgttggg aatagcaaaa catcccgaat
       61 tgattgtgca tcagttagca acattactaa tctgtcgatc ccgatgccta gaccaccagt
      121 tggcggcata ccgtattcta aggcttccaa gaagtcttcg tctacaccgt gagcttcgtc
      181 atttcctagt tcacgttctt tttcttgcgc ttcgaatctt tctctttgat caattggatc
      241 gttcagttct gtaaaggcat tagcaaattc gcgccccact atgaatagtt cgaatcgatc
      301 tgtgaatcga ggatcttctg gatttttctt cgctaaaggc gaaacttcga ctggatgtcc
      361 gtatacaaac gtcggttgtg tcaatgtttc ttcaacaaat gtttcaaaga attcattgat
      421 aacatgtccg acacccatag cttcggttac ttctacattg tgtttttcgg ctaaagctaa
      481 tgcttcttcc aatgtcattt cttgccagaa gtctacacca gtttgttctt tgattgcatc
      541 taccatatgg atgcgtttaa agtcactttc taagtcgaca gcttgtccat catatgtgat
      601 ttttgctgtt cctagtactt tttcagctgc gttacggata ataccttctg tcagattcat
      661 tacatcattg aaatcagtat atgctgtgta tgcttctaac atcgtaaatt ctggattatg
      721 tgtagtatca attccttcat tacggaaaac gcggccgatt tcataaactt tttccattcc
      781 gccaacaatt agtcgtttta aatgaagttc tagcgcaata cgcaaatata aatcaatgtc
      841 cagtgcatta tgatgcgtga taaatgggcg tgcggcagct ccacctgcct cattgtgcaa
      901 tactggtgtt tctacttcaa tatagccatt gccatctaaa tagcgacgga tttcgctgat
      961 aatttggctt cgtttcataa atcggtcaaa gctttcgcga ttactgatta aatccaagta
     1021 gcgttgtctg tagcgttgtt caatattcgt taagccatgg tatttatctg gcagtggacg
     1081 aagtgctttt gacaaaatcg tgatttctga agctttgata gaaacttcgc ctgtgtctgt
     1141 tttcatgatt tgtccagtta caccaaagaa atctccaagg tctgcatgtt tgaatacttc
     1201 ataggcctca tcacctactt ggtcttttct tacataaatt tgaatttggc cttcacgatc
     1261 ttgtagatgc gcaaatccag ttttcccttt tcctcggcga gtcatcatac gaccagctac
     1321 actagcggtc aatcccattt ctgctagttc ttcttttgtt cttggatcaa atagttcatg
     1381 caattcttct gagttgtgcg tgcgttcaaa tcgttttcca aatggatcga ttccatcttc
     1441 acgcaattgt tccatttttt gacgacgtac aagcatttga tcatttaaat cttctacttg
     1501 atgttgttgt tcctgtgtca caaaagttcc tccattctca tgttaatctc tttcctataa
     1561 tgccaatgaa acacaaaaaa agcaagccga acttggaatt tcggcttgaa aattcacgaa
     1621 aaacttagaa atcacaacgt ttgtttcaat agtacttttt ccgctttttc tacaaattga
     1681 tccagcaggt cattgatttc ttgctgtttt tctgtctgat tgattgctac tttcactttc
     1741 gctgctcgag gaatcccttt taaataataa gccgcatgtg ttctgaattc tctacaagct
     1801 actttttctc ctttgagatc tgctaagcgt tgtaaatgaa gtttagctgt agcaattttt
     1861 tcggctggtg ttggttcagg aatcagttct cctgtttcga gataatgctg tgtgcggtga
     1921 atcatccatg gattgcccag cgctgcacga ccaatcatca caccgtctgc accgacatag
     1981 tcaagcatcc attttgcatc ttctggcgtt ttgacatccc cgttccccat aaatgggatc
     2041 gtcaaatgtt ttttcacttc tttcaatact tcccagtccg cttttccttc atacatctga
     2101 acccgtgtac gtccatgcat agcgatggca cttgctccag ctgattgtgc tgctaatgca
     2161 ttttctacag caaagacgtg ctcttcatcc caaccaatac gcatcttgat tgttactggg
     2221 atatttactg ctgaagaaac agcttggacc atttcgtata ctttctcagg atctaaaagc
     2281 cattttgctc ctgcttctgc tttgattact ttatttactg gacagcccat attgatatct
     2341 attatatcgg cagctgtgtt ttcttcgaca aattgagcag cttcaactag actatcttta
     2401 tttccgccaa atatctgtaa acttaatgga tgttctgttt cttcaatgtg gagcatctct
     2461 aaagtttttt tgtttctgaa atgaatacct tggtcactga tcatttcaca tacgactaag
     2521 cccgcaccaa attctttgac agtgactcga aatgctgaat ttgttattcc agccatcggt
     2581 gcaacaacga cacgattagg gatttccaca ttgccaattt tccatgtgtg ttccacttaa
     2641 atccctccta aggcttcttt cttcaatcca tctaattctt cttcgctata cttgtatttg
     2701 ttattacaga aagaacaaac cgcttctgca ccgtgatctt cgtctatcat tgcttggatt
     2761 tcttctgcac ctaacgcgat aattgcttct gcaaattttt cttttgaaca gtcacatttg
     2821 aattgaacag gcattttttc caaaatgttc aattcttctg taccaagcaa tcctttcaat
     2881 atttcttctg gtgtctgtcc ttcatctaag agggtagaga ttcttggtgt cgtttttaat
     2941 tgttcttcga tcttgctgat tgtttcttca tcggcacctg gcatgatttg gatcatgaat
     3001 cctcccgccg tcttgatgct gtcgtcagta ttgaccaata cactcagtcc aacagctgaa
     3061 gggatttgtt ctgagatagc aagatagtaa gtaaaatctt cagcgatttc tccagaaaca
     3121 atcggcgttt gcccagaaaa aggttctttt aatcctaagt cttttgtgac agtaaacatt
     3181 ccttgtgttc caactgctcc ccgcacatcg attttacctt cactatttag aggaagactg
     3241 agatgcggat ttttgatgta acctttcaca tctccctttc catttgcatc tactacaatt
     3301 cctgttgctg gaccatcgcc ttggattcga acagttagtt tgtcttctcc tttgagcgtc
     3361 gcaccaagta gcagactacc gaccaatgtc cgtcccaaag cagctgagga ggtgtgccaa
     3421 gtatcatgac gtctttgtgc ctccgctacg gtatttgttg cttgaacggc gtatgctcgg
     3481 acgaatccgt cgtgagcaag tgccttaacc aaataatctt tcatttgtta tgtactcctt
     3541 tttccgtttt taaactcata gtgaatcata ctagcaacta ctgctttttt caactttgga
     3601 atgcttcttt taaaaataat tcagaatcat ctagaaaaca ggacatcacc ctatttacaa
     3661 cttaaataaa gaaatctccc gaaaaccggt ttttgttccg gttttcggga gtcatatcag
     3721 atcaattgac ctatattttt ttatttgtat tgatcgtctg aatgattatc ttctgattgt
     3781 tgagaatctg aatcatgttc tgctttattt tcctcattca gttcatgttt tgcttcttca
     3841 aaatcacgtt tttcttccgc ttgtttttca gcgtcttttt cttccaaagc acgttttgct
     3901 tcttcaaaag ttttcgcttc tttttcgctt ggataatcat ttgactcagt accttcaggc
     3961 atcacaccgt gttcaaacaa tgacttgatt gctttggcat ccaatgtttc gaattccaaa
     4021 agtttttcag caatcagttt atgctgtgca cgatgagctt cgatgatttc tcgagcttta
     4081 tcatgagctt ccatcaagat ttttcgtact tcttgatcaa tctcgaaagc gacttgttcc
     4141 gagtaagctt ttgtttgacc atagtcgcgg ccaacaaaca cttgatggtt tccttcatat
     4201 tgaacaggac ctaaacgatc actcattcca tattctgtta ccatgcttcg tgctagagct
     4261 gtcgcttgct caaagtcatt ggaagcacca gttgattgga cattgaagat gatttcttca
     4321 gctgtacgtc caccaagtaa gcctacgatt tgttcaaaca tatcttcttt cgtcatcaag
     4381 aactgatctt cttttggtaa agcgatcata tatccgccgg cgcgtccgcg agggatgatc
     4441 gttactttgt ggacgacccg agcgcgactc aatactaatc cgacaatcgt atgaccagct
     4501 tcgtgataag caaccatttc gcgttctttt ttgctgatta cgcgatcttt tttagctgga
     4561 cctgcaatca cgcgatcttc cgcttcatcg atatcagaag catcgatttt ctttttattt
     4621 cttctagcag ctactaacgc tgcttcattc aagacatttt ctaaatctgc tccggcaaaa
     4681 cctggtgtct gttgagccac aactttcaag tcaacgtcat ctgccatcgg tttattccgt
     4741 gcatggactc gcaagattgc ttcacgacct tttacatctg gacgtccaac taaaatctgg
     4801 cggtcaaaac ggcctggacg tagtaacgct gggtctagta catcagaacg gttggttgca
     4861 gcaatgacga ttactccttc atttccgtcg aagccatcca tttctacaag caattggttc
     4921 aatgtttgtt cgcgttcatc atgtccgccg cccataccgg caccacgttg acgacctacc
     4981 gcatcaattt catcaatgaa aatgatagct ggtgcgtttt tcttcgctgt ttcaaacaaa
     5041 tcacgaacac gacttgctcc aacaccgaca aacatttcta cgaaatcaga acccgagatc
     5101 gagtaaaacg gtactccagc ttctccggca acagcttttg ctaataaggt tttacctgtt
     5161 cctggaggtc cttctaaaag tacacctgcc gggatacggg cacctaattc aacaaatcgg
     5221 cgaggatctt tcagaaattc aacaacttca actagttctt gtttttcttc ttccgcaccc
     5281 gctacatcag aaaaacgtac gcgattagct tttttgtctg cttctttggc ttttgattta
     5341 ccaaagttca tgacacggcc gccaccgcca ccgccgccgc cttgttgtcc catcatcatg
     5401 taaaagaaaa agatgatgat tacgattggc aagaagctaa gcaataggga aacccatata
     5461 ccgctgcttg attcttcttt tactgttgta gcaactttgt tttcttttgc cagttctgtt
     5521 acttggctca atgttgtatc atttggcaaa atgattgttg tgaaatgggt agtagtcgta
     5581 tctgttgaac ctaagatagc taacccaccg ctgttagcga cggtctgctg ttctttgtat
     5641 tcaccagtga tcttatatac accatttgca ggctgcactt caaattcttt gatcttgcct
     5701 gcttgtagtt gttctgtgaa ttttgagtac tcgatatctg acgatcgctg gccgttatta
     5761 ccaaaaatga aataaacgac cattaccatc gctaagatta cgaggacata atacaaggca
     5821 tttttcatca tgccgttgtt ctttttgttc atagttgccc tccctaagcg tcaatttaat
     5881 ttaacagttt tttatcaatc ctgaccattc tattgtacca taatttaatt gagatacagc
     5941 attaatttga ttgataaaca ctaggtttca atacaccgat gtacggaagg ttacgatatg
     6001 cttctgcata atccaagcca taaccgacca caaattcatt tggtacgttg aagccaacat
     6061 aatctgcttc gatatttact actcttcctt caggtttgtc aagtagtgta acaattttga
     6121 ctgattttgc tttgcggtat ttgaaaagat ccactaaata agcaagtgtt cttccgctgt
     6181 caatgatatc ttcaacgatc aacagatcgc gaccttctac attcgtatct aagtctttga
     6241 cgatttttac ttcccctgac gagactgttg cattcccgta gcttgaaaca tccatgaaat
     6301 ccaattccaa atacgtatcg atagaacgaa cgatatctgc catgaatggt accgctcctt
     6361 ttaagacacc tactactagg ggattggtgt tttggtaaat ttctgttaac tctttgccta
     6421 gttctttgca acgaacttgt atctcttctt gtgagatcaa aattctctca atatcctttt
     6481 ccaacatcag gttctccttc caattgcttc tttttgatat ttgtaaagaa gtatgtagtg
     6541 tattttatca gtttcttcac gaatactcaa atatgaaaag gcaaaaggta tcaagctata
     6601 tatatttctt ttggcatctg taatgatcca agcatgctgc ctttgtgaat taggtacttt
     6661 ctgatcgata aaatatctag atactttttt tgtgagattc tctgttaatt taatgcggtc
     6721 tcctgctttt cttttttcga catacagttg cacatcagca ggaatccaaa tgtcatgaga
     6781 aaatagagac catgaatctg ttgctttgat gtcccctgca ttttcaggtt tgaccagacc
     6841 aatccattct gtttcattca aatatattcc ttgttctgga atcagcaaca agcgctggtc
     6901 ttctgtctgg ctagttgctt gtttttcttt tttagagagt acaacaaaat gatactctct
     6961 tttcagtatc caattattgc caatactgag ttgccattgg ctttttttct gttgccactg
     7021 gtctaaaatc gactccattt gttgttcttt caaaataatt cctgtttttg agaatgcttt
     7081 gtcgaaaaag gagtaaaaaa aatagtatcg ttcagcatct gtcatttctt caatcatttc
     7141 tgcagaaaat cgaaattgtt cctcccactg ttcgacttcc ttttcgatca actgtcccat
     7201 atatttttga atgacttggt ctgcccattg gatctgttgc gaaaattgct ggaaatgtct
     7261 caacgcctgt gtattttctt gtttcaattg aggaactacc aaatgacgaa gccgatttct
     7321 ctggatatct aacaattggt ttgtctgatc ctcaaagtaa acaagctgcg attccgctgc
     7381 ataagtatat aggtcttctt tgctaaaact cagcaacgga cgaatcagtc tgcccgtagc
     7441 aaatggttgt acttctttga ttccagaaaa agtatttaac tgtcccccac gaacgatttt
     7501 cattaacacc gtctcgattt gatcatctcc gtgatgagca gtcatcaacg tgtcatattg
     7561 tccttcttcc atcacgcgag tgaattcttg ataacgaaag ttacgagctt ctgtttctat
     7621 ggcggatttg gctggatctt cccaaatact tacatataaa gggagattct tctcttcaca
     7681 atatgagcga agataggcag cttcttctgc tgattcttct cttaattggt gattgatgtg
     7741 gacgatacct aaagaaaaac cgatttggcg ttgcacttgt aaaagtaaat ggagcaaaac
     7801 catcgaatca acaccacctg ataccgctgc taaaattctc gatccttgtt gccagaatcc
     7861 ttgttcattc ccgtgccgaa taaatgactg ctgtaatagc ggtgcttttt tcccgccttt
     7921 ttcaacgttc atcctttcca caccctttct tcctaaaaaa aagagagcgg gaaaacgtct
     7981 aaaacgacaa ttaacctgcc ctctgttgat actatgaccc aaatagtcgc actatcatta
     8041 tttgcggctt tttagctgcg acgtccgcca cggccaccgc gctttccttc tgtgtttcgc
     8101 ttcaatgaag ataagcggtc atcgctatct ttcaaaaatg aactcatcaa tgaatcgaag
     8161 tcttcttttt gagctgaagg ttgactgcga gaaaaagatt ttttctgtgc tggacgattt
     8221 cggttgtcac ggggatcttt ttgttgatat tttttaggac ggctttcttc tccagattca
     8281 gcaggttgtt cctgcgcttt ccggatagat agtccgattt ttccatcatc atttactgaa
     8341 ataactttaa ctgttacttc atctcctaca cttaaaacat catggatgtc ttttacatag
     8401 ccatttgaca cttcgctaat atgaactaga cccgtttttc cagcacctag atcaataaac
     8461 gcaccaaaat ttgtgattcc tgatactttt ccttgcagtt ttgctcctac ctcgattgac
     8521 ataaaaaaaa tgttcctcct aattatttcc cttttttata ttcctgctta ttttgcagtt
     8581 gtagaactag ttgattgatc tgtttcattt gtcgagctgt ctgtatttga ttctaatata
     8641 ggataaactt tttcaccgtc ttttgagtaa aagaatttgc ttctggcaag tttagctaca
     8701 tactcatcat ctttcagcaa tgaaacatct tggtgcagct gatcaacgtc tgcgttgact
     8761 tctttcattt cagtatttgc ttcgactctc aattcgttca attgatgcat cctttgcatg
     8821 tcatggaaaa tctgcacacc tattatcgcg aaaatgacca aagcaccaac aaaaattgca
     8881 gccagtctgc gtcttcgaaa aatcagttga cgttgttgtt gctgaaattc agcatacttt
     8941 ttctttgcat attccgtatc tagcgcagcg attttattgc tttttttcgt cacttggatt
     9001 cgctccaatc tttttgattg tctttttcat tataccaata tcgtgaaagc ttgtctaatc
     9061 tatttctcta gtgtttctgt gcgattttca gaaataattt cgtacatttt ttgtgcatct
     9121 tcttttttgg ttgattcatg taattccgta attttcactt ccaacgtttt gttgccaaac
     9181 tggactttca aaatatcgcc tactttgaca tcactggaag atttcgccaa tttaccgttg
     9241 atttgaattc ttcctttatc agctacttct tttgctactg atcgtctttt gatgattcgg
     9301 gaaattttta aaaatttatc taatcgcata tcttattcct cactttttaa tttttttatt
     9361 taatcgcagg attttcttac caaaaggcaa cattagccat tctcgtactg taaacagacg
     9421 aagacgaatc actgcataaa tgaacacaga agccccgatc ccaactccta tcacgctgac
     9481 aaaaaaagca gtggaacgat gagttacagg accaaatact atattcaata caccataata
     9541 cagcagcagt actactgtca tacaaagaag gctgaacatc aacttccgtc caaaatgccg
     9601 ttctttccaa aaagcattta gctcttttgt ttcaattcga acaaaatacc aaagcgtcac
     9661 acctaatcct aaaagggtag acaggcttgc acctgctgtt cctaataaac cggtcagaaa
     9721 agaagtagtc aatcctttta ccaatagtcc ccatcctgcg ccttttaaag aagggcgaaa
     9781 cgagttcttg ctttgagcaa tactttgata agcttggatg actgcagtga aagcaatgga
     9841 aaaaacaaat aatacaagcg ctgcatttcc cgcataatct ttaaacaacg cataattgat
     9901 ataagggagc agcaaggcta atcccaaaga cgcagctaat gctaaagcgg tcgtcaatct
     9961 aagatagatt ttggctgtct gtaaaaactg acgatagatc cggttggtca aatgacgagt
    10021 caacgcaggc aggaatgtcg cacttaatgc agtggcaatc actaaaccta attgtactaa
    10081 aggctgacct cgatcataga ccccttttgc tatcttcgca ccgtattctg acagtccgta
    10141 aacttccaaa gcatttttta caaagaaaga gtcgatcagc tggaaaaaga taagcaatcc
    10201 actataaatc gaaaccagtc cgccttctac cagaaaacgc cggatcaagg gctttgacgg
    10261 ctgtttgaac aatggaaacc gtcggaagct taacgctcct ccatgaatct tttgttcata
    10321 gtagtgaagg atcccatatg cgcataaacc gccaaaaaca gctccactca ttgctgccgt
    10381 ccctgtttgg tacaccgtcc atccaagctt tctaaaagca aacgcactac agacaatcac
    10441 aaaaacacga acgaactgct caactacttg agaaacagca gttggttcca tcaagaatct
    10501 tccttggaaa ttccctcgat aaaaagatag accaggcatc agcaaaaagg taaaggaaac
    10561 tacttggatc agcggtttca attgtatgtc tcccatcatc caagcaatcc agctgctaaa
    10621 tgcaaagaca aacaaccaca aaaagacacc tgtccaaaat actaagggat aaagattttg
    10681 caaagcttgc tttcgctcga aaggattctt tctttctgca acgtactttg atatgaactg
    10741 cggaagaccg gataaagcta aagtcattgc tatcccataa attggataaa cttgctgata
    10801 aacataaaaa ccttcgtcgc cgactaagtt ttggagggga attcggtaaa gggcacttaa
    10861 tacttttgct atgaaagaag caatcgtcaa tacaaatgct ccttgcatga cgcgccgcat
    10921 ttctttatga tccaaatcat tgctccttcc tacgctgaca gatatttttg ctcacgcaac
    10981 gctttgacaa acttttggat ttcctgaagc catactgctt cttccatttg gttggggatc
    11041 gtcaagcgta tcaccatctg ttctttttca acgcctagac tggcttttag ttttgtcgct
    11101 gtcagtgctt cgaataactg ttccacacta tagcgttttg ttccaacttt acttagagta
    11161 aagactatat gcgcctcctg tttccttatc gtttctagga gcgctcgatc gccatccatt
    11221 ttgatctgcc caattgtcaa gagatgtgct acttcttctg gatattctcc aaaacggtcg
    11281 agcagatcat cttctagttc atctagcatt tcttgcgaat caagttcacg aattcgttta
    11341 tagatctcga ttttctgccg ttgatctgcc acgtatgttt caggtagata cgcatcgaca
    11401 ccgaggtcga tctcaacagt ggtcttctcc acttgactat tctttccttg tttacgagaa
    11461 acagcttcgc ttagcatttg agaatacata tcgaaaccga ctgcatcaat aaatccatgc
    11521 tgctgagcac ctaagagatt acctgcaccg cgaatggaaa gatcccgcat cgcaatcttg
    11581 aatccagatc ccagttctgt aaaatctttg attgcctgaa gacgtttttc actgacttcg
    11641 ttaaggatct tctgctgctc atacataaag taagcatatg cgacacggct gcttcttcct
    11701 acccgccctc gcaattggta taacgtggat aatcccatat aatcagcgtt ctcaacgaac
    11761 aacgtatttg cgttcgggat atctactcct gtttcaatga tggttgtagt gacaagaaca
    11821 tcatattgac cttcaataaa ttcaaaaagc gtattttcta attgcgcctc tgtcatttgc
    11881 ccatgagcat aaccgatccg tgcttccgga acgagttctt ggatttcttc tactttttgt
    11941 tcgatcgttt ctacccgatt atataaatag aatacttgtc cacctcgtcc catttctcga
    12001 tggattgctt cgcgaatagc cccaggattt ttttccataa catacgtttg gatcggataa
    12061 cgattcgcag gcggtgtttc gattactgaa agatcccgca cgcctaacat cgacatatgc
    12121 aaagttctcg gaatcggtgt tgcagtcaga gtcaaaacat ccacttgtgc acgtaactgt
    12181 ttcaatcgtt ccttatgttt tacaccaaaa cgttgttctt cgtcaatgat cagtagaccc
    12241 aaatcgctaa attcaatatc ttttgacaaa attcggtggg ttcctacaac aatatcaact
    12301 tgacctgtac gcagttgttc gatggtttct ttttgttgct ttcttgttct gaaacgactt
    12361 aatagcccga tatttacggg gaaaccttca aatctttcca gcatcgtttc atagtgctgc
    12421 tgtgccaaga tcgttgttgg aactaaaaag gctacttgtt tgctttcctt tatcgcttta
    12481 aaggccgctc gaagcgctac ttctgttttc ccataaccaa catcacctac gagtagtcga
    12541 tccattggtt tttctttttc catatcccgt ttgatctccg ctgcacttct caactggtca
    12601 tcagtttcag agtaggggaa ggcattttcg aattcttttt ggtaggcgtc atcaggtcca
    12661 aaagcatatc ctttttctga ctctcttgcg gcatataatt tgattagatc gtcagcgata
    12721 tcctcgattt ttgaagagac ttttcgcttg gttttcgtcc attcacttcc gcctagctta
    12781 ttgatgcgag gcgctttggc ttcagaggcg acatattttt ggatcagatt cagttgagta
    12841 acaggaataa acagtttgtc gtcgttttga tacaaaatag tcatatagtc ttggtgaacg
    12901 ccatctactt ctagcgtttc catcccaatg tatttcccga taccatgatt ggcatggaca
    12961 acgtaatctc ctgcttttaa ctcattatag cttttcaatc gctctgcgtt tgttactgtt
    13021 tgacgtctcg tttgtttttt cgtcgttttt tggaaaattt ctttttctgt gatagctact
    13081 attttttctt gaggaagttc aaaaccagcc tgcaaagctc cttcaactaa ttgtacctgt
    13141 cctctgatca atgcattttt ttctgtttct actactaata tgtcttcatc tcgaagcatt
    13201 tgttctgctt tgcgtattct gtcctttgtc ggaataaaga tcacaacagt ctgtttttgc
    13261 ttgcgccaac ggtccatttc tgttttcagc aatggcattt gtccgaagaa ctgttgcatc
    13321 gtccgatatt gaaaattatg gattgcttgg aaacgaagat ttcccatccc tttttggaag
    13381 agtgagaaaa aggttgtggt gaacttttcc ttctgcacga ttttttgtat atctgctgaa
    13441 aatgtctgct cagaaaacac ccgcaattcg ctgatttttt gagtctgcca ttctgccgct
    13501 tccctttcga tttcccgatt tgtttccatg attcgctgat aatcatcaac gactagtaaa
    13561 ctatttgaag ggaaataatc caagatcgtc acagattctt ggtaaagaag atctgagtag
    13621 aattttgctt cttctgtcgg gacacctgct tgccagcttg aagtcagctg accgaagtaa
    13681 tcttgcaaaa actcgcggtc tgcttcttct gtggtcgcag caagccgttt ttctagcatt
    13741 ttttgcattt gctctattcc atgttctaga tcctctggtc cgtagacttg ttcactcgtt
    13801 ggggaaaccc agatttcttc cgttttttcg attgagcgtt gtgtttctgc ttcaaaatac
    13861 cgcatagaat ctatctctac atcaaatagt tctacacgaa caggataggt tgtcgttaac
    13921 gggtaaatat cgataatgct tcctcgaata ctgaattctc ccggttttgc gaccatctct
    13981 tctcgtacat agcccatcaa agtcaattgg cgaggaagat tttccacgtc tatctcatca
    14041 ccaatatgcc aattcaattg cgcctgtagc caagttttct tattcggcag tcgtttgtgc
    14101 aaagatgcga ctggcaacaa atagatacct gctttttttt cttgaagtgc gttaagcgtt
    14161 gcaactctct cgcctcgcgc ttctggagaa gaaaaggcca tttcagcaga aagcacttca
    14221 tccactggaa ataaatggat ctgatcttgc ggaatcacat gttgcagatc ttctgctaac
    14281 tgattcgcat aatacaaatt tggcatcaga ataatcatgt ttttatttgt tttcttaaac
    14341 gctcgagcaa atagaagtgt tttcgctgag cccgctaatc ctgtgattag ttgtctaggc
    14401 attttttctt ctaaattgct gacccattct tttacttgcg gatcttttcc gactaattga
    14461 ataatatcca ttccttttcc tccttcctca attgaatcga ttcatcgcat ccacgaacga
    14521 atgcccttct atgagatatt cgactgcttt aacagattga cacatgcttt cttctatcaa
    14581 aggctgattt tctttgctga aaggactaag cacatgctgg actactgttt ttttcccttc
    14641 tggcctgccg attcccacct tgattcgatc aaagacattc gtattcaaat gggaaataat
    14701 acttttgata ccgttatgcc cgccggcact tcccttttga cggagccgga tttttcccac
    14761 tgccagatcc aaatcatcgt agattacgac taattcctct ggataaatcc caaaataagt
    14821 cattagtggg ccgactgcac gaccagattc attcatgaat gtttgtggtt tgactaaaag
    14881 gatcttttct ccattatgaa aaaattcggc aacttctgct tcgaacggat tttttttgaa
    14941 agtagcttga tgctcgcgtg caattttatc cacgaccata aagccgatat tgtgttttgt
    15001 atattggtat ttggtacctg ggtttcctaa cccgacgatc attttcattt ttgttttcca
    15061 cctaattcta aaaagcagca caaaaggctg gactgctaat tagcggtcca gtccatcgag
    15121 cttttttctt ttttatactt gtcaatgcat agtataacac aaaacaaggc gtttcggcta
    15181 aaagagaatc gttaataaat gataaagaaa ttaaaaattt cttcaaagtt taatgaaata
    15241 attgatatat aaaaatagtg aaataacgca catgtaagct tttacatata atacaacctt
    15301 gttatctgtt atattttata gccaaatagc gtgacatggg gcttgagaaa tgttagcata
    15361 agcatgggaa aaaacaaatc aatggaagga ttgatactaa atgactgcag ctgcagaaaa
    15421 aaaagatcat caaaaagtta ttcttgttgg agacggcgcc gtaggttcta gctatgcctt
    15481 tgctctagtt actcaaaata tcgctcaaga agtaggtatt gtggatatca atactgctaa
    15541 aactgaagga gacgcaattg acttgtctca cgctttggca tttacttcac ctaaaaaaat
    15601 ctattctgct acttacgcag acgcacatga tgctgactta gttgttatta cagctggcgc
    15661 accacaaaaa ccaggtgaaa ctcgtttaga cttagtaaac aaaaacctaa aaatcaaccg
    15721 cgatgttgtc acacaaatcg ttgaatcagg atttaacggt atctttttag ttgccgctaa
    15781 cccagtagat attttgactt actcaacttg gaaattctca ggtttcccta aagaacgcgt
    15841 aatcggttca ggtacctctc ttgactcagc tcgtttccgt caagcacttg cggaattagt
    15901 tgacgttgat gcacgtaacg tccatgctta catcttaggt gaacacggag attcagaatt
    15961 cccagtttgg tcacatgcaa atgttgccgg cttgcaaatc tatgaatggg taaaaaacaa
    16021 cccagaaatc gatgaagaag ctatggttaa cctattcttt ggcgtacgtg acgctgctta
    16081 cacaattatc gagaaaaaag gcgctacttt ctatggtatc gcagtagcat tagcacgtat
    16141 cactcgtgcc atcttagatg atgaaaatgc tgttcttcct ttatcagtat tcatgaatgg
    16201 cgaatatgga ttgaacgaca tctacattgg tgcacctgct gttatcaacc gtcaaggtat
    16261 ccaaaaagta atcgaaattc ctttaagtga cagcgagcaa gaccgtatgg ctgcttctgc
    16321 taagcaatta aaagaaattc tagatgaagc ttttgctaaa ctagacgctg aataatcttt
    16381 gaacatgacg gaaaacatct attcggtgtt ttccgttttt ttattttatc acccttatgg
    16441 tttctaaatt ttttcataaa gtagagataa ccttcgtctt ttcctctaaa ttatgctatc
    16501 atgagaccgt tccaccctaa acttttactt aaggagttgt cgatatgaca agatcttcgc
    16561 atcgaaaaaa atcgaaacat gttgctttgc tttcagttct tggtgttctc ttagtgctga
    16621 tcagctttta tacctatcgc agtacatact acacaaagca ttttttgccg aatacagaaa
    16681 taaatggaat aaatgtcagc aatctaacag tcgaaaaagc aaatgaaaaa ttaaaagaag
    16741 cttattctga taaaaaactg gctattaaag aagatggaaa agtctggcag gaagtaccaa
    16801 aatccgagct cggctacaaa gatgatttca cttcggagct ttctccgatc ctaaatgaac
    16861 aaaacggatg gacttgggga atgacttatg tctcagcggc agaaaaacaa gaaatagatc
    16921 ctgtcagtca aaaccaccaa aaactagaca ctaccgttca gacattgaca actaagctga
    16981 ctgatttgaa caaagaccgg acacctacta ctgatgcaac gatcgaaaaa gcaggtgact
    17041 ctttcgttat caagcctgaa gtcaatggaa atacgatcga cgtcgatgct gcggtcaaac
    17101 aattaaaaag tgcggtaaac tctggtaaag atacaattga attgactgaa ttcaaagaaa
    17161 aaccaaaagt aacatctgaa gacagctcac tgaaagaaca actcgcatcc atgaatgcta
    17221 tcgcaaatgt aaaagctact tacagtataa acggtgagac tttccagatc ccatcaagtg
    17281 atattatgag ttggctgacc tacaatgatg gaaaagtcga tttagataca gaacaagtac
    17341 gtcaatatgt aacagattta ggcacaaagt ataacacaag tacgaatgac acaaaattta
    17401 aaagtacaaa aagaggagaa gttacggtcc cagttggcac ttacagttgg acgatccaaa
    17461 cagacagtga gacagaagca ttgaaaaaag cgattctggc aggccaagat tttactcgtt
    17521 cacccattgt gcaaggtggc acaaccgctg atcatccatt gatcgaagat acgtatatcg
    17581 aagttgatct ggagaaccag catatgtggt attacaaaga cggaaaagtg gcccttgaaa
    17641 cagatatcgt ttccggaaag ccaactacac ctacacctgc tggagtcttc tatgtttgga
    17701 ataaagaaga agatgcaact ttaaaaggaa caaatgacga tggaacacct tacgagagtc
    17761 cggtaaacta ctggatgccg attgactgga caggtgttgg tatccacgat tcagactggc
    17821 aacctgaata cggtggagac ttatggaaaa cccgcggttc acacggctgc atcaacaccc
    17881 caccaagtgt aatgaaggaa ttattcggga tggtcgaaaa aggaacgcct gtattggtct
    17941 tctaacaaaa ataatatata aaaagaaagc acccgtacga ttggtacagg tgctttcttt
    18001 ttattatcta acaatgtgct acttacattt cagcagcagt aaagacttct gaaacatcat
    18061 catcgtcttc tagcttatct actagacgtt ccaattgctc tttttgttcc tcatttaaat
    18121 caatcgtcgt ttgtggaatc atcgtcaatt ctgcttgcgc caaagtgaac tctttttcca
    18181 actcatctcg tacagcagca aaatcttctg gtgcagtata aatctcgaat acttcaggag
    18241 aagtttgcag atcttctgcc cccgcctcta atacatcctc aaacatcgtc tcttcatcaa
    18301 cagtcaaccc atcgcgttca atagcgatat atcctttgcg gtcaaacaag taactgactg
    18361 aacccgtttc tcccagtgat ccaccgtttc gagtaaaagc tactcggaca tttgtcgctg
    18421 tccgattacg gttatctgtc aatgcatgga ctaagattcc tactccaccc ggaccatatc
    18481 cttcatacgt gatttcatcg taattcgttt catctacggc actcgtagcc tttttaatcg
    18541 cccgttccac attgtcgtta ggcatatttg cagcttttgc tttgtccaca acaagccgca
    18601 aagctggatt catagatgga tcaggaccgc ctgctttagc tgccatataa atttcacgag
    18661 aaagtttctg aaagactttc cctcgttttg catcttgggc attttttctt ccttggatat
    18721 tatgccattt actatgtcct gacatgattt ttcctccctt gttcttttga gaatacactt
    18781 ctattctagt actatttcac aaaaaaacaa agccacagcc aatctataaa cgcttcttga
    18841 atgccgcaaa aagcacacat aatatcacag cagtcagagc accgatcgaa tccaacatga
    18901 catcttggaa cataggtgtt cgtccaccgg tcatcatctg atggaattcg tccaaacctg
    18961 cgtaccctgt tgctgaaagc caagcaagga tcgctgtcag ccaccaaatt tttagcttgg
    19021 ggaaaacacc taaaaacaag ctgcctccca aaataaaata ggtaccgaaa tgtgcgccct
    19081 tccttaaaaa gaactctaaa aatttggcgt agcccagatg gtcgatactc accatacttc
    19141 caccataatt aaaacgtata cccgctaatg tgtctttaaa tggctgatta ggcagccagc
    19201 tttctaatcg cgaaacttgt gattgctgtc cgtaagtttg agaagaactg taaaataaga
    19261 ttataacgac tatcagtgcg attactaaat aaatatttcc gtttttcatt tgtttttttg
    19321 aagaattcat aagtcacctc tgtattttat cttagacttt ttttgaagaa acaacaatca
    19381 ttttcataga gacttcttcc ataaaaaagt gctatactta attttgtatt acaatatgaa
    19441 gggagttttt tcatgagtta ttcattaaat tggaatctag attctatttt ttccggaggc
    19501 agtcattctg atgctttgaa ccaacggatg aagcaattgg aagaccaaat gaacgagtat
    19561 tatcaccgcg taacaaaatg gtcacctagt tctgacaatg cagagcagtt aaacgctatt
    19621 cttcaattgc aagaaacgat tacgaatggt tttacccaat gcagcagcta tattactgca
    19681 ttgctttctg ccaatgtcaa tgattcagat gcaaaggtct tatcaggcaa gctttacgca
    19741 atgctgcctc gtctgcaatc agccgaaact gtattgtcaa agaaatttgc agaaatatct
    19801 gacaatgatt ggaatcagat gctttctcaa tcttcgtttg aaacaattgc ttttcgttta
    19861 aacgagattc gtcgtgatgg ctcacaatta ttatcagaag ctgaagaaaa cattataaat
    19921 acgctttctt tagatggtct aaatgcttgg agcagtcatt atgatacgat tgtagccagc
    19981 atttcgattc ccttcgaaca agatggacaa gtagtcgaat tatctgctgg acaagccttc
    20041 aataagatga tgggcgatcc agatccaaaa gtcagagaaa cacttttcgc agcatgggaa
    20101 gaagcctgga aagaaaaggc acccctcttc acggatactt tgaatcattt agatggtttt
    20161 agactttctg actatgaact tcatggtgtc acagattttc tacaaaaacc attagagtac
    20221 aatcggttga agaaagaaac attgtctgtc atgtgggata caatccagaa aaacaaacaa
    20281 ccccttgtta attacttgac tagaaaagct aatcttttcg gtaaagaaaa aatggaatgg
    20341 caagatcaag atgcacctat tattttaggc gatttgaaag aaaaaacctt tagttttgac
    20401 gaagcagcag catttattat cgaaaacttt aacaaattca gtccaaaaat ggctaaattt
    20461 gcccaatctg cttttgaaaa gagctggatc gaagcagaag atcgtcctgg gaaacgtcct
    20521 ggtggttatt gtactgagtt accagaaaca aaagaatcaa ggatctttat gacctacagt
    20581 aattctgtta atgaggttgc gacacttgct catgaactag gacatgcttt ccatagcagc
    20641 acgatgtggg atttaccttc tttaaatcgc gaatatgcca tgaatgtcgc agaaacagca
    20701 agtacattcg cagaactgat cgtagccgat gctacattaa aagtcgcaaa aacaaaagaa
    20761 gaaaaaatca atttgctaga tacaaaactg caaaatgctt tagctatgtt catgaatatc
    20821 cattcccgat tcatttttga aaatcgattc tatgaagcac ggcaagaagg attagtctca
    20881 gaagataaga tcacagagat gatggttgag gcgcaaaaag aaggctatca aggagcttta
    20941 gctacttacc atccatattt ctgggctgca aaattgcatt tctttattga tgacgtaccg
    21001 ttttataact tcccatacac atttggctac ctctttagtt tgggcatcta tgcttacgcc
    21061 aaccaaaagg gagcaaattt tgaagaagaa tatatccatt tactacgcga tactgcctca
    21121 atgacgacgg aagatcttgc gaagaaacat ttgaatgtcg atcttaccca accagatttt
    21181 tggcaagcag gtatcgacat ggtgactgaa gatatccaaa cgttcatgga attgacagaa
    21241 gaatttatct gatttctatt ttatcacaat aaaaaaagag ttagtccaga atgggctaac
    21301 tctttttgat taatcattct tacatgctga cagcaaagtc aggggcaaac cattgaactg
    21361 aaccaacttt tacgctttcg cctggttgag gagcatggat atattgtcct ccgcctaaag
    21421 caatcgctac gtggtaagtt ccgccttgtg acccccagaa taacaagtct ccagcttttg
    21481 cttgagaaac tgaaattttt gttccagctg attcttgagg aactgtccaa ccaccgatgt
    21541 cacgaccagt tacttgcatg taaacatagc gtgtgaaccc tgagcagtca aagccacttg
    21601 gatctttacc gccccaaaca tatggagtac caatatattt gtaagcttct gctacgattg
    21661 ctgcaccatt cacacttcca gaaggagctg gagcaggtgt tacaggtttt ggttgttcag
    21721 gtgttggtgt tggcgttgga gccggagtac tacttcctgt gccgtttcct gtatcaacac
    21781 tttgatctgt tgatggtgtt gtaggcgcag gtgttgttga ttcttctgtt gttgaagatt
    21841 caggcactgt tgttgattct tctgttgctg aagattcagg cactgttgtt gattcttctg
    21901 ttgctgaaga ttcaggcgct gttgttgatt cttctgttgc tgaagattca ggcgctgttg
    21961 attcttctgt tgaagattca ggtgttgttg attcttctgt tgctgaagat tgtgtagctg
    22021 atgatgattc ttcagtcatt gaagattgtg tagctgatga ttcttctgtt gctgagcttt
    22081 gtgcagtaga tgaagcttga gtagcttgtg cttcagcctc tgcttgttcg cgtgcttctt
    22141 tttcagcttt ttcttgtgca gcttgttgac gagcttgttc tgctagacgt tgttgttcac
    22201 gaatacgagc ttgctctgct tcagcttctg ctttttgacg gttcaagtca gctttcttgt
    22261 cttcagcagt tgcttgttca gcagctaatg aagttttcag tacgttcaaa tcagcttgtt
    22321 tagataaaag atcgcctttt tgagattcca aagcagcttg gttttcagct aattctttta
    22381 gtttagcatc gttttcagct tttttgtctt ctacagcttt tttatcttgt ttttgttgtt
    22441 ccatcaagtc gttgtttgct tttaccatcg ttgtcattgc ttgaacgcgt ccaatagcat
    22501 ctgctaatga atcagcattc aatacagcat cgatgtagtt tgagcttgtg ttgcttactt
    22561 gtgcttcgcg tgcttgtttt tggattgtat cttcacgttt ttcaatacgt tcttgtaaat
    22621 ctgcaatgtc ttttactaat tgtgcagatt cttgacgcaa tgtatcttgt tttgctaata
    22681 ggtcttgtgc ttgtgtgttg atttcagaaa cttggctttc taaggcatcg atttgtgatt
    22741 gtgcatctgc ttgttgattt ttcaagtctg caatcttttg atcttgctgt tgtatctgag
    22801 aatcaaaatc gtccgccgcg gcagcgatcg gtgatgctac ggcagtcaag gtcattgaac
    22861 ataccattac tgctgatatt aaactctttt tcactcttca ttcctccgac tggcttaatt
    22921 taataaatat ctaaatatat ttaagtcttt cttaacgata taaaaattgt accatagcag
    22981 tgtgtcaacg atataatagt tatgttacaa aaatgtttca aaacaacttt taaaaatgac
    23041 aaaactgttc gtttcagaaa atgatcatga aaaagccgcg ttaagtctag catttcttaa
    23101 gataacaacg attctttttc gctttcgacc taaaaataaa aaaagaaatt attcatcact
    23161 gaataatttc ttaaagggaa aaatgaataa tacaaatata atcatgttca acagcagtgt
    23221 aggtcctaaa aaccttgtaa taaaatacgt gttatttact actgctaatt taaaaatcaa
    23281 ctggaccacc atcgtaaaca attcataacc cgtgacaaag atgatcatac tgaaaaattc
    23341 agtaaagatg ttgacatgga taacgtcttt cattacatac atcaaccata caattaaagg
    23401 gagagctact gcatagatac cgataacgcc aatatagtaa gcgtcataga tagccccgag
    23461 aacaatcgtg gtaatcagta aataacgttt ttcaaacgcc atactgcaac ataataatgc
    23521 caatatcaga aagtgggcat ttgacatata ggtgcctttc gaccactccc ctagcattct
    23581 tgttaaatga ccatctatca acatcaaaaa gaacaaaacg attggcagat agtacttcat
    23641 tgtttctttc ttcaacatgg actaatcctc cgctagccgt tggacaatcg tcacaactga
    23701 cacgtcatac atttctgcat aaggtttcac ataaacttcc cgatccagcc cataactatc
    23761 tggtttcgtt ttaataaccg taccgatcgg caagttagct ggagaattcc ctccaagacc
    23821 ggatgtctgg acaacatccc cttctttgat atccgtatca ccagttaatt gggtcaccac
    23881 taaggcatgg agcttttcat catagttttt aagcaaacca aacgcttcgc cattagccga
    23941 agatacccgt actggaaaat gattggagct ttcattagag gatgacagta attcgatttt
    24001 agacgaagcc gtattgacct cgatcactcg gccaatcaat cctttttgcg acatgactgc
    24061 catatttgct tcgataccgt ctttagaacc cttgtctacg atcagcatgt cctgccaact
    24121 gtcaggcgaa cgagtaatga catttgccgt tactttttcg taactagtca gcgtctgatt
    24181 caactcaagt tcttttttca acgcttcgat ttctctctcg taattcttgt tttgctgtga
    24241 aacgtcatca tagctatcga ttttttcttt tagccgctca ttttcggcat aagttgaaaa
    24301 aagattatgg acagaatcta ctccatttcg tacccaccgt actggggcag agattgtttt
    24361 atcaaccatt gcaacactgt cattaacgat ggattggaag aaattgggct ttccttcatt
    24421 cgctcgctgc gcagcggtca cacttagtat cgtcaccacg atgataacaa taaccaaggt
    24481 aataataata tttttattag gattgaactt cttcacaaag acacctcgaa ttaattagac
    24541 tcttgtgttc aattttatca ctaaatgccg tgaaacaaaa ggtaagttgc tcctcttaag
    24601 ctttttttta gcaaataata gattctgtca tttttagcct gaaagacaaa tttttttatt
    24661 tgtttatgga tcaatctttg ctttgaataa ctgcaatcat accatctgaa aaagaaaatt
    24721 ctgcggtatc tgaaagaaat tcgttacttg cataagatgt cggatattct acttctttat
    24781 tttccaatac atacttgctg ccttttaatg taagattcga gacgggagtc aagcagcaat
    24841 aagctaaata cttcatatct ggtatctgtc ttactatatg ctctccaggc aaataataag
    24901 acaaataatt ttgacaatct ctgataataa gctgatgggc aaagggtttg aagcgaggtt
    24961 ccatacctaa ccagagattg gctaaaagat gatccaatct tccgcccgta gctccaatca
    25021 aagtgacttc cgcttgcggg taacgttcaa atgtttttaa gatacctaac tgtgtatctg
    25081 tatcgtcttt ttctgcaggg gaacgggtat actctttggc ttttgcaaat acttccttct
    25141 gctcttcgtt cgacaatgaa tcaaaatcgc ccactgccag atctactggg tagcctgctt
    25201 gaagcaggta cagcgcacca cggtctatcc cgacataggc atcgtatttg gacagcagag
    25261 actgcggcca gttttgcgga ttacctccag cagctaataa aattttcatt tagtctaatg
    25321 cctcttttaa tcgttcgatt tgtccgactg gattttcggc tccatagata tatgatcctg
    25381 caacgaagac atccgcccct gcatctttac agatttttgc tgtttctgga acgattccgc
    25441 catctacttc gattgcataa gtccaattgt tctctctacg tagatcagcg agttccgtaa
    25501 ttttttctac tgtttcttca ataaagcttt gtccgccgaa cccaggattg acagtcatga
    25561 ctagtacttg atcagccaaa ggcaaaacat gtttgatcat ggagactggt gttcctggat
    25621 tgataactac tccagcttta actcctaagc tttttgtcat ttgaagtgcc cgatgaatat
    25681 gaggagttgc ttcgacgtgg acagtaatga tatctgctcc agcttttgca aatgctggaa
    25741 tgtagttttc tggatcaacg atcatcagat ggacgtctaa cggtaattta gtaacaggac
    25801 ggattgcctg aacaatattt ggccctaatg tgatatttgg gacaaattgg ccatccatta
    25861 catctacgtg gatgtaatct gcgcctcctt tttccactaa ctcaatgtct ctttgtaaat
    25921 tggcaaaatc tgcactcaaa atggatggtg ctatcttcat tcttgtttcc tcctattttc
    25981 gtttaccttc tttttttgca tacattggtt ttcttttttc gatttcttgt aagaattgca
    26041 aataattgtc gtaacgtgtc tgtgcgatac cacctgtttc tactctatgt tttacttcgc
    26101 agccaggttc tttagcatgc atgcactctc taaatttgca atggacagaa gcttctacaa
    26161 attcaggaaa ttgtctcggc agttctcctg cttcaattgt caaaaagtca atcgagctaa
    26221 atcctggtgt atctgctact aacccgccat agataggaat cagttccaca tgacgtgttg
    26281 tatgccgtcc tcttccaagt gcatcagaaa tctctcctgt tgctaaattc agttccggtg
    26341 atatttgatt cagtagcgtc gattttcctg ctccagactg acccataaag accgatagcc
    26401 gttctgggaa gtaacggatc agttctgtcg tatcacccgt atgattgggt acaatcaccg
    26461 gatagcctat tttagtatag gtttgcttga tctcttcgat tttttctggg tcgtctgaca
    26521 agtcggtctt tgtcaaaaaa ataatcggtt cgatcgactc gtattccaag gtaactagaa
    26581 agcggtcaag tagattataa gaaaatgcag gctctacgat acttgtgaca atgattccaa
    26641 gatcaacatt tgtgactggt gggcgaacta attgattttt tctcggcaag atttccagaa
    26701 gatagccgtc tgtttgattt tcactctcaa agatcacctg atctccgaca agcggcgtga
    26761 ttttccgatt ccggaaattt cctcttcctc ttgtttgata ggtctctccg tttgcgtata
    26821 catagtaaaa accgctgatt gcttttctga tttgtccttt gataagtgcc acctccgttt
    26881 ttgtttattt taccatacga agaggaaagt aggtgttatt ccatgcaaac ttctcaaagt
    26941 atatggcttg aaaattgatc aaaagagata gaaacacaaa aaagagaatg caacaaatca
    27001 atgtcgcatt cccttctgat atattttatt cagcacttat tttgaacttt ctgaggtgct
    27061 agctgatgaa cttgtggagc tggaagattc ttcttttgaa gagttgcttg tgctactgga
    27121 gctacttgag ctgctagaac tgtctgaaga gtctttttca gaactagaag acgctggatc
    27181 tggtccttta gagtaaatta cgttcacaac cattcctttg gtaattgtcg ttcctgcccc
    27241 tggtactgta cgaatcactt tatctttatc caccgtgttt gaatattcgg aagtctcatg
    27301 cccgatatat tctgcaccga cactagctaa ataactttgt gcttcgcttt ttgtatagcc
    27361 ggagatatca ttcaatttag gctctgttcc ttggcttacg acaaaattga tgtaagtttc
    27421 ttctgctaca acttcacccg aggctggatc ctgactgatg atcgaacctg atggtacagt
    27481 gtcgctatag tcataagtag cactaatatt attgatattg aatccttgtg taacaagcca
    27541 attacgaaca gtttcgtagt tttctcctac atgactactc aaagtcactg tttctggtcc
    27601 tttgctgact gtgaaagtaa tcgtgtctgt tttaggatcg acttctgtat cttctgatgg
    27661 agattgcgaa atgatcattc cgctttctac ctctgaactg aattcctctt ctttttgaat
    27721 caagtcagca gaaaacccta attctttcaa acttgcttcg gcatcttcat aacttttacc
    27781 actgtaatca tctaatttga tttttttcgt gccgctacta atatacagag tgacttcgcg
    27841 tttttgcttg actgtcgttc ccgctgccgg gtctgtcttc actacattac cttcttcgat
    27901 tttgtcatct gcaatttctt ctgtttttgt tgctacttct aatttcgctt ttgcgagtgt
    27961 ttctctagca gaagcttcag aaagatcaga aacatcagga acaacaactt ctcctcgccc
    28021 gccagaagca aagaatacag ctgttccgat tcctaaaaca gcaagaatag ctaataggat
    28081 cagccaccat tttttctgtc ctttcttttt aggatcaggc agaacttctt cctcctctgg
    28141 caaggtttcg ttttctggct tgtcttttgg cagaggcata gatttgaatg aatcaggcat
    28201 tggtgcatct tccgtaaggg gtgtgataac ttttgtttca ttatccatca catgaggctg
    28261 ccatttttct tcgtttgcac gagctggtga taatactgta gaaagatcat cagacatttc
    28321 ctcggctgac ttataacggt ctgcaggttc tttagccgtt gcccgtaaaa tcacgttttc
    28381 cagtgcttgt ggcacatttg gatcaagtgc ttttatagat ggaagatcat cttgaaaatg
    28441 ttttaaagca attgttacag cagattcacc atcaaacggt acgctacccg tcaacatctc
    28501 ataaaggatg atccctaaag cataaatatc tgactgcttc gttgccatac ttcctctggc
    28561 ctgctcaggg gacagataat gaacagatcc cagcatcgta ttcgtctgcg tgatcgatgt
    28621 ttcagataaa gcgatagcaa tcccgaaatc cgtgattttt acaacacctt cattatcgat
    28681 cagtacgttt tggggtttca aatctcggtg gatgatttga tggttatgag ctaaagaaat
    28741 agcagaaagg atctgctgca taatatttac tgctgtttca taaggaacag gataatgtgt
    28801 ttggatatat cgtttcaagt ccattccttt gacgtattcc atcaccagat actgcatgtt
    28861 gtcttcttca ccaacatcgt aaacactaac aatgtttgga tgaacgagtt ctgttgctgc
    28921 taaagcttct ctctgaaatc gtcgaatcgc agtctggtca ttttgaaagt caaatcgtaa
    28981 gactttaact gctacatcac gatccaagat taaatcgtgc gccaaaaata catttgccat
    29041 accaccgcta ccgatatttc cagtgatttg ataacggcca tttaattttt tgcccaactc
    29101 gatcatacac tgtcctcctt atattcgata agaagaacgg tgatattatc cgctccgcct
    29161 gcttcattgg cacgatcaat cagctcagtt actttatgag acaatgggcc ttcttgattg
    29221 atgatcgttc ctatttcttc ttcagacagc atgttcgtca agccatctga acataacagc
    29281 agtcgatctt ttagttgcca aagatgagta gaaacatcta cttcgactgt tccaggcatg
    29341 ccgacagaac gtgttaaaat atttttcctt ggatggttca ctgccatttc ttcgctgatt
    29401 tctcctgatt tgactagttc attgactaaa gaatgatcct ccgtcaattg catgatttta
    29461 tcttcacgaa tcaaataagc tctgctatcc ccaacattgg caatcgtgaa ccagtcatct
    29521 gacagagcgg ccgctacgat tgttgttccc ataccgttat attccggctg ttcttgtcca
    29581 cgctgataaa tcagcatatt ttcttcttga atcgattgaa tgaaccattg ggcgattttt
    29641 tcatcgtcaa cagcttcttg tttttcccaa gcttcgccta gattcgttac cgccatctga
    29701 ctggcaatgt ctccggcacg atgaccaccc atcccgtctg ctaatacagc aagcttgaga
    29761 cctgaacggc tggtaaatac actggcatag tcttgatttg tgttacgtcg tcttcctaca
    29821 tctgattgat attcaatctg cattttttca cctcattact ttttgcgcaa acaacaaatg
    29881 aaaaatccat ctgtgtaaaa ctgatgcgga tacaaagtca acattttctc ttcgattgat
    29941 gattgtagca taggattggt caaaacatca atcctctcaa aatcagggtg tctttccaag
    30001 aaagcagaaa caacgtcttg gttttcttct tttaagatcg tacaagtgct ataagtcaga
    30061 ataccggaag actttaaagt tggtgcgcag ctttctaaaa tttccaattg gatttttggt
    30121 aaattcgcta attcatccgg ctgtttttta taacgaatat ctggttttcg ccgaagcagc
    30181 ccaagacctg aacaaggcgc gtctactaaa atccgatcaa actgctctgc ttcgaactgt
    30241 ttactgactt ctctagcatc catcttttga gcgtagacag cagaagagac acctagacgt
    30301 gctgcattat cttcaatgag tttgactttg tgttcgtgta catctaaagc gaccacttct
    30361 ccaccgcatg acggatctaa aaaagaagca atatgcgtcg tcttacctcc gggtgctgca
    30421 caggcatcta agacatgatg ttcaggctcg atttgcatag acggcgctac aagcatcgaa
    30481 ctttcatctt ggatcgtcat gacgccatcg tggaacaatg agctagaagc taaatgccct
    30541 tttttcgcta ctataccgta tggactgact tggctttttt cagctgtgat ctcttcttct
    30601 tgcaaaacag tgatggcctg atctctggaa agtcggcgtg tatctactcg ggcactagca
    30661 tggctaggct gatatagcga taaaccgagc ttttcagttt cttcgtatcc gatttgatcc
    30721 accagtcgtt tcgtcatcca tagaggcagg ctgattttga cagaaagtct ttcgatagga
    30781 tcagcaatgc cttgcagatc tggtgctcct tgacgctgat aattcctcaa gacaccattt
    30841 acaaatttcc ctgtcccagg atttcctttt acttttgcga tttcgaccgc ctcgtttaaa
    30901 atagcatgtg cagggacttt atctaaaaat tctaattggt atacagaaag ataaagaagc
    30961 gtcttgaccc agtcatccac tttttttgct ttagcgatca atggtgcaac gtaaaattcc
    31021 aatagtcgct gatggctaat cgtaccatag atcaattctg taaataaacc cacatctttt
    31081 tgatttagct cgctttgttt gatcatctca ttcaacaaaa gattcgagta ggcgccaccc
    31141 ttgttcactc gctctaatgt cagtaatgcc atatatcgta ctgatttttt cattttttta
    31201 gggatttttt tcattatttc acctgctgac caatctgaac ttgctgaccg cttccgttaa
    31261 ggaaatcatg tacggcctgt tttcctttac cagctggctg taattcattg atggctaaga
    31321 cggtctgttt accgcaagca atccatagat tttttttgtc tttccggatg atcgtaccag
    31381 gtgctttgtc tgtagtttct gccaatactt caaccgataa taatttccag cgtatgccct
    31441 cataggtcgt gaatgcaatt ggccaaggac gcattccgcg tacttggttg tcaatttctt
    31501 ctgcagtttt atgccaatcg attgcttctt gttcccgtgt gatgtttggc gaaaaagttg
    31561 cttctgactc gtcttgaggt actggttttt gtccatccaa aatattgggc aatgtttcta
    31621 gcaatagctt tcttcctaaa aggctaagct tttcaaacat cgtccctaca tcatcttgtt
    31681 tagtgattgg tatgctttct tgcgcataga ttccgcctgc atccattttt ttgatcattt
    31741 ccatgatcgt tacaccagtt tctttctccc cattcatgat ggcataatga acaggcgcac
    31801 ctccccgata tttaggaagt aaagaagcat ggacattgat tgcccctaat tttggtactt
    31861 gcaataactt ttcaggcaag aattggccaa atgccgcagt gacgatcaca tcaggcacca
    31921 attcaatgat ttcttccatt tctggcgaac cggagatttt ctctggctgc agcacacgga
    31981 taccgtgctt cagagccgct tcttttaccg gtgtcggcgt aattactcgt ttccgcccaa
    32041 ctggacggtc gggctgtgtt accactgcct ggatctcgta acctgattct atcagccctt
    32101 caagaatcgg cacagaaaaa gcaggtgtgc ccataaatac tagcttagtc atcaagatgt
    32161 tcctccatat attcttcaag ttcttcttcc gggatctgct gtatcatttt ctcaatgaac
    32221 aagataccgt ctaagtgatc gatttcatgc tggaaggcac gggctaaata gccaaaagcc
    32281 gtcacttcta tctcttctcc gtctcgatca taataacgca cggtcacttc atctgctcgc
    32341 ttgaccgttc catagacatg cggaatactg agacaacctt ctacgtcaag gctttcacct
    32401 tttgcttcga tgatttctgg gttaatcagt tcaaatttct cgccttcatc tacttcgatc
    32461 acagcaattc tcttgttttg tcctacttga ggagcagcga tccctattcc gtcattcgca
    32521 atcattgtct catataaatt gtctaataaa gcgattgtct cgtccgtgat tacatcgatt
    32581 ggctgagcag ttctttttaa tttatcatta gggtggatca atataggata gcgcataatt
    32641 tggccctttc ttaaataaag tttaatggtt cgttgtcaat tgccacaaaa agaccttgtc
    32701 gctgttcttt ctggcttcca ttcaaaattt catccaaaac atgaggaaga ttcggttcat
    32761 gtttatattt gatgattagt tgataataat atcggttttt cactctcaaa atcatgctgg
    32821 gcgttggccc taatagcaag ctttgagggc ttaacacttc ttttagctga ttggcaatct
    32881 gaaagatttt ctttgccgct acttgttctt caggatggct ggcggttatt ttcacagtaa
    32941 agtaataagg aggatagcct ccacgatgcc gtacatgcat ttcctgctga taaaactgct
    33001 cataattttg ttttttagct aattctatgg cgtaatgttg aggattgaat gtttggatca
    33061 cgacttcgcc tgctttttcc gctcgccctg ctcgtcctga aacttgggta agcaattgga
    33121 atgtatgctc actagaacga aaatccggta aattcaggga ggtatcagca ttcaacaccc
    33181 caactaatgt cacttctgga aagtccaaac ctttagcaat catttgtgtc cctaataata
    33241 tatctgcttc ttttgcaccg aatttttgta aaatctgttc gtgtgcccct tttcttcgag
    33301 tggtatctac atccatacgc aaaatcctag cttgcggata aagttctcgg agttcctctt
    33361 ctactttttg agtacctgtt ccatagtagc ggattttatt gccgccacaa ttaggacagc
    33421 gattgggaat aggttcttca tgtccgcaat aatggcagcg cattgaacgt gtatccatat
    33481 gcagtgtaag agagatatcg caattaggac atggaagaac aaatccacag tccctacaca
    33541 tcacaaaaga cgaatatcct cgacgattga gcagtaggac agtttgttct tttttgtcta
    33601 atcgattttg tattttttcc tgcaaattag cagaaaaagt agaggtccga tgattctgaa
    33661 actcttcacg catatctacg atctcaatag ctggaagctg tgcagctgct ttggctcggt
    33721 ggtttaactg caataactga taaacgcctt tttgagctcg tgctcttgat tctaaagagg
    33781 gcgtcgcgct tcctagaact attgggcaat gatgatattt actgcgccaa attgctagat
    33841 ctctcgcatg ataacgcggt gtctcatctt gtttgtaact tgattcatgt tcttcatcga
    33901 taatgatcag cccgatattt ttcagcgggg caaaaatagc agatcgtgcg cctactacta
    33961 cttgcgcttc ttcccgctca atcttgcgcc attcatcata tttttcacct tgggaaagtc
    34021 cgctatgtaa gaccgcaact gattctccga agcgtccttt gaatcgctcg accatttgcg
    34081 gagtcaatgc gatttcaggc actaacataa tagccgtttt attttctgac aaaacatcag
    34141 cgattgcctg aagatatact tctgttttcc cgctgccagt gattccctcc agcaaaaaga
    34201 cctgatcttt ttgctgctga cctgctgtga tgatttgttc gacagcattt ttttgttctg
    34261 cattcagttc caatgccgtc gtttggtcaa atactcggtc tttataaggg tcgcgataac
    34321 gttctgattc tataaactcc agccagccct tttcttttcc ttgattcaag acagcagtac
    34381 tgattccttt atttttgaaa taagcaattg gttcttcttg gctcagttca gataaacaca
    34441 aaagaagttc tttttgtttc ttggcatttt gccgtaattt tgcccattct tcttcgattt
    34501 gcttttcagt taacaaagaa cggaccaaac gaatcgtttt tactttattt cgtgtatgga
    34561 cttcatattt gatatctact aattgctctt ggcgccagcg aatcaattga gaaaggctgc
    34621 cttcttcttc tgcttccttc caggaaatca cttctcgctg atcaaacaat acctgaactt
    34681 ctggtgtgtc tgccaaagga tagatcaatt tatcatattc tgctttcatc acactcggaa
    34741 gcatcgtttg tagacaagtg attttgaatg cgtaagtaat ttttttcata taatcagcta
    34801 atgaaagtaa ttcttcattg accaccggag caaggtctag caaacgaata actgccttca
    34861 aagatggatt agctgattct tctgattttt ggatagccat aacaaatcct tggacatgac
    34921 gattgccatt accaaaaggg acttctactc gcatcccgac ttgcaaagct gtttccattt
    34981 cagagggaac caaataagtg aatggctgat cggtctgcat agtaggtacg tccacaatga
    35041 cttcagctgt taatgtcatg gttcgtttcc tccttttttt gtcttttctt atcaagcgac
    35101 aaaaagttcc ttgcctattt tactagagat cgatggattt gtcttatctt ctgccaaatc
    35161 ctaacaaaaa attaacagca gataagaaaa aaaagaactg tgtcaaaaag ttcagacaca
    35221 gccttttcta ccagacaata agtggcgaat gtttgaaaag gaaacagctg ggtttgcttt
    35281 tctttttaga tgttcgctct atttttcttt attacatttt ttgctcttca cggatacgtg
    35341 attccaattc gtgttgttca cgctcttttt gtgcttgacg ttcctcttct tccatcttca
    35401 aacgttcacg ttttaattca ggatgtggat cattgactac atttcctgca tcgatttctt
    35461 ctaaagcttg accgacgctt tttactgaat caaaagaatc tagagtaggc tgtgcacttg
    35521 catccaattc atgcgcgcgt ttacttgcta aaatcactag agaatatttt gaatttacac
    35581 gatctaatag tgagtcaatt gaaggtttta acatcataag actacatctc ctttaacatt
    35641 ttaatatatt taccgattac gcgatctact cgaaaatgtt cactggcaat aatgtttttg
    35701 attcgttcaa ctgctagcgg cacttcatca tttacaacag catagtcgta aagagccatc
    35761 atttcgattt cttcttttgc aactttcatt cgttcttcga ttacttcatc tgcatctgtt
    35821 cctcggccta cgatccgtga ttttaattcc gctaaatctg gcggagtcaa aaagatgaat
    35881 acaccatcgg gcactttttc tttgacttgt tttgctcctt ggacttcaat ctccaagaaa
    35941 acatcttttc cttcatccaa tgtcttgttg atatatgaca aaggagttcc ataataattc
    36001 ccgacatatt ctgcgtattc cagcatctct ccagcttcga tcattgattc aaactcttct
    36061 ttgcttcgga agaaataatc aacgccttcg acctcccctt cacgcatttt acgggtagtc
    36121 attgagatcg aatactgaaa atcattatcc tcactctcaa aaattgcttt tcgtactgtg
    36181 ccttttccta caccggatgg accagacaac acgattaata atccacgctc tgacatgacg
    36241 acgtcctttc aactagtctt tttgtactta tcgtttattt tgcacttttt ttctgcaact
    36301 ttcaaggtta tctttaatta tagctagaaa ttggtaaaaa agctaccctg taccaagagg
    36361 tcgtaaaaaa gctgtcctgc atcaagtaat aagaacagcc aaacataaac agcttctcat
    36421 gtttttcgtt tggttggggt tattatcgca gatgcaagct tttgaacgcc gtgtataaga
    36481 ggtcgtgaag aagccgatta gtttcgagta tgaagaaaaa ttttgtgaaa atagtttctc
    36541 acatttttgc ataaatttgg cttaatac
//
LOCUS       DACDAF010000018        36213 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.018, whole genome shotgun sequence.
ACCESSION   DACDAF010000018 DACDAF010000000
VERSION     DACDAF010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36213
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.018"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..752)
                     /locus_tag="IVZ69_000846"
     CDS             complement(<1..752)
                     /locus_tag="IVZ69_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP8182954.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIV"
     gene            923..1291
                     /locus_tag="IVZ69_000847"
     CDS             923..1291
                     /locus_tag="IVZ69_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HAP8182955.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            1461..1892
                     /gene="mraZ"
                     /locus_tag="IVZ69_000848"
     CDS             1461..1892
                     /gene="mraZ"
                     /locus_tag="IVZ69_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HAP8182956.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            1913..2872
                     /gene="rsmH"
                     /locus_tag="IVZ69_000849"
     CDS             1913..2872
                     /gene="rsmH"
                     /locus_tag="IVZ69_000849"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HAP8182957.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            2877..3284
                     /gene="ftsL"
                     /locus_tag="IVZ69_000850"
     CDS             2877..3284
                     /gene="ftsL"
                     /locus_tag="IVZ69_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HAP8182958.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRIRKVK"
     gene            3285..5477
                     /locus_tag="IVZ69_000851"
     CDS             3285..5477
                     /locus_tag="IVZ69_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HAP8182959.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            5503..6465
                     /locus_tag="IVZ69_000852"
     CDS             5503..6465
                     /locus_tag="IVZ69_000852"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HAP8182960.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            6479..7840
                     /locus_tag="IVZ69_000853"
     CDS             6479..7840
                     /locus_tag="IVZ69_000853"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HAP8182961.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            7866..8954
                     /gene="murG"
                     /locus_tag="IVZ69_000854"
     CDS             7866..8954
                     /gene="murG"
                     /locus_tag="IVZ69_000854"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HAP8182962.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            8969..10189
                     /locus_tag="IVZ69_000855"
     CDS             8969..10189
                     /locus_tag="IVZ69_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsQ-type POTRA domain-containing protein"
                     /protein_id="HAP8182963.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            10345..11670
                     /gene="ftsA"
                     /locus_tag="IVZ69_000856"
     CDS             10345..11670
                     /gene="ftsA"
                     /locus_tag="IVZ69_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HAP8182964.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            11693..12934
                     /gene="ftsZ"
                     /locus_tag="IVZ69_000857"
     CDS             11693..12934
                     /gene="ftsZ"
                     /locus_tag="IVZ69_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HAP8182965.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            12951..13628
                     /locus_tag="IVZ69_000858"
     CDS             12951..13628
                     /locus_tag="IVZ69_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HAP8182966.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            13642..14241
                     /locus_tag="IVZ69_000859"
     CDS             13642..14241
                     /locus_tag="IVZ69_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HAP8182967.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            14256..14543
                     /locus_tag="IVZ69_000860"
     CDS             14256..14543
                     /locus_tag="IVZ69_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HAP8182968.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            14592..15374
                     /locus_tag="IVZ69_000861"
     CDS             14592..15374
                     /locus_tag="IVZ69_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HAP8182969.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            15395..16102
                     /locus_tag="IVZ69_000862"
     CDS             15395..16102
                     /locus_tag="IVZ69_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HAP8182970.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            16364..19162
                     /gene="ileS"
                     /locus_tag="IVZ69_000863"
     CDS             16364..19162
                     /gene="ileS"
                     /locus_tag="IVZ69_000863"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HAP8182971.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(19211..20737)
                     /locus_tag="IVZ69_000864"
     CDS             complement(19211..20737)
                     /locus_tag="IVZ69_000864"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HAP8182972.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(20752..21399)
                     /locus_tag="IVZ69_000865"
     CDS             complement(20752..21399)
                     /locus_tag="IVZ69_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HAP8182973.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(21583..21912)
                     /locus_tag="IVZ69_000866"
     CDS             complement(21583..21912)
                     /locus_tag="IVZ69_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HAP8182974.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            22089..22817
                     /gene="sfsA"
                     /locus_tag="IVZ69_000867"
     CDS             22089..22817
                     /gene="sfsA"
                     /locus_tag="IVZ69_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HAP8182975.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            22833..23846
                     /locus_tag="IVZ69_000868"
     CDS             22833..23846
                     /locus_tag="IVZ69_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP8182976.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            23846..25123
                     /locus_tag="IVZ69_000869"
     CDS             23846..25123
                     /locus_tag="IVZ69_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP8182977.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            25186..27888
                     /locus_tag="IVZ69_000870"
     CDS             25186..27888
                     /locus_tag="IVZ69_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8182978.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            28040..28357
                     /locus_tag="IVZ69_000871"
     CDS             28040..28357
                     /locus_tag="IVZ69_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8182979.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            28387..28707
                     /locus_tag="IVZ69_000872"
     CDS             28387..28707
                     /locus_tag="IVZ69_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP8182980.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            28815..30275
                     /locus_tag="IVZ69_000873"
     CDS             28815..30275
                     /locus_tag="IVZ69_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8182981.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            30343..30564
                     /locus_tag="IVZ69_000874"
     CDS             30343..30564
                     /locus_tag="IVZ69_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182982.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            30595..30777
                     /locus_tag="IVZ69_000875"
     CDS             30595..30777
                     /locus_tag="IVZ69_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HAP8182983.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            30777..31190
                     /locus_tag="IVZ69_000876"
     CDS             30777..31190
                     /locus_tag="IVZ69_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HAP8182984.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            31313..32494
                     /locus_tag="IVZ69_000877"
     CDS             31313..32494
                     /locus_tag="IVZ69_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8182985.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            32883..32956
                     /locus_tag="IVZ69_000878"
     tRNA            32883..32956
                     /locus_tag="IVZ69_000878"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32917..32919,aa:Arg,seq:cct)
     gene            complement(33025..34164)
                     /locus_tag="IVZ69_000879"
     CDS             complement(33025..34164)
                     /locus_tag="IVZ69_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8182986.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(34463..35098)
                     /locus_tag="IVZ69_000880"
     CDS             complement(34463..35098)
                     /locus_tag="IVZ69_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182987.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(35211..35846)
                     /locus_tag="IVZ69_000881"
     CDS             complement(35211..35846)
                     /locus_tag="IVZ69_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HAP8182988.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(35880..>36213)
                     /locus_tag="IVZ69_000882"
     CDS             complement(35880..>36213)
                     /locus_tag="IVZ69_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182989.1"
                     /translation="PFKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTV
                     MFTKKYWNEMENLKKYIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDF
                     KKKELLGL"
BASE COUNT        11938 a         6177 c         7488 g        10610 t
ORIGIN      
        1 acgattgctg aaaaagtctg attcatttgt tctactagtt ttaattgaat gcgagaagta
       61 gtcattgcct gctctgtttc caccaataca tcacgtaaat gatttttcaa agcatgattt
      121 tcttggaaaa gtttattttg cgctagttct ttcaatgcat ctaaattagc agaagtcgct
      181 tctctgaaat aaacgaggct tttttggata tccatgattt gataaagttg tttgttttca
      241 gtggatactt gaagtttggc ttccaaagta tcgcattgag attgaagcgt agctaaataa
      301 ctgttgtaag agagtgtgac ctgccaaatg aattgaaaga agatattgag attaggcgaa
      361 atatcacttt ttggaaaggt ctggctaaag actttcttta aaaacagtgg ttcatgattc
      421 gtaattgtga taagcttctt tttgggcgtc aaaataatag agagcgggta tgtatccact
      481 tgaaaataac cgctaggact tgttttagca aaaggatatt gtaacaataa taacgctggc
      541 tttgtcaact ttgattgatt gaattcttct gtacgggaat tttctgcatc gtccaatatg
      601 gaagtgatgt aatctgacgg aatttcaaat tgatgtgtca gctgatgaat ctcttcttga
      661 ttaggacgtt ctacacaata ccagatcgtt tggtcagttt cctttccggt attacgcagt
      721 ttctcattat ctaatgtaaa atatttgatc atgattttcc tcctgttgcc tgtttctttt
      781 attataacgg atagggaatt ggaatacatg gaatgtgttt gtaagatata gaatataact
      841 gcataaattt aaataaaatg aaacagttgt gtaaagtata tacagtatac ttgaagcaac
      901 gataaaaaag gagtttacgt tcatgggcac attcacacca cttatcttgt tttggtatat
      961 ttacccggta atcgttttgt ttggttgcca atttcttgta aaattatttt cgttaaatcg
     1021 tcgttttaaa ataaaagccc ctgatttggc gattcctttt ttgtggggcg gtatgcatgc
     1081 attgtctaga aatacaggga caatttctat cttaccgttt ttctttattt ctgttttgct
     1141 aatgggaatt tgtattgctg ttttccaagc atattattat gaagaaatta tttatccgcg
     1201 ttatttcaag atgacttggc gtttggtttt tctgttgaca atcgtcttgt acgctgtctt
     1261 gatcattgtg aacatacttt cttacctatg aaaaaaatag aaaagctgta aaaagtcttt
     1321 taaaaggctt tttgcagctt gatttttaaa aaaatgttta tgaataaaaa aagttgttcc
     1381 cggatttccc agaaaaggtg gtagaaagtg ggggattgtg gtagactaat tttagttagt
     1441 ggaggaatgg ggggctttca atgttgatgg gtgaattcca acataatatt gatgcaaaag
     1501 gacgtttaat cgtgccctca aaacttcgtg aagaacttgg cgaaaagttt gttctgacac
     1561 gcggattgga tggctgtctt ttcggctatc cgatgagcga atgggaaaat ctggaagcta
     1621 aactgaacga aatgccgttg gctaaaaaag acgcacgtac ttttgtgcga ttcttctatt
     1681 cggctgccac tgaatgcgaa cttgataaac aaggacgaat caatataccc agcacgttaa
     1741 gaaattatgc agctttgaca aaaggttgcg tagtcatcgg tgtatctaac cgaattgaaa
     1801 tttgggatga gacacgatgg caagattttt ctgcagcagc agaagagaac tttgacgaaa
     1861 ttgctgaaag tatgattgat ttcggactat aagaatagga agaggctgac taatgactga
     1921 aacatttcaa cactatacag tcatgttgaa agaaacggta gatggattga acatcaaacc
     1981 ggatggcgtt tatgtagact gtacactcgg cggtgccgga catagtgaat atttattaag
     2041 ccaactaagt tctaaagggc atctgtatgc gtttgaccaa gatcaaaaag caatcgatca
     2101 cgccaagctg cgtttagctt cttatgtcga acaaggtatg gtcacattta tcaaagcgaa
     2161 cttcagagaa ttagaagaac gcttgagtga gcatgtagat aaggtagacg gcattttgta
     2221 tgatctaggg gtttcctctc ctcagctaga tgaagcagaa cgtggattta gttatcatca
     2281 agatgcaccg ttggatatgc gcatggatca gtcagctcct ttatccgctt atcacgtaat
     2341 taatgaatat tcctaccatg aattagtaaa gattttcttc cgctatggcg aggagaaatt
     2401 ttccaaacaa attgctcgtg aaatcgaacg agtacgaaaa acaaaaccaa tccaaacaac
     2461 tggtgagctt gtcgaaatca ttaaacaagt catcccagct cccgcaagaa gaaaaggcgg
     2521 gcatcctgca aaaagaattt ttcaagctgt gcggattgca gtaaatgacg aactcggtgc
     2581 cgaagaggcc tctttagaac aggcaatccg gttattgaaa gtcaatggaa gaatcagcgt
     2641 aatcacattc cattcattgg aagacagaat tgtcaaaagt atgtttaaag aatatagtac
     2701 ggtacaagat ctaccaccgg gacttcctgt catacctgac gaattccaac cagaactgaa
     2761 agtcattact cgtaaaccaa tccttccttc agaggaagag ctaacagaaa acaatcgatc
     2821 acgcagtgca aagttacgta ttgcagaaaa aataagaatg aaagaggagt agaatgatgg
     2881 cagaattaaa gaaaatgcaa gattacgaat atgatttacc tgaattggtg gatcagccgg
     2941 aacaacaaat gcctgattct tcttcgaatc aagaaatcat tcttccacaa tcaccggcaa
     3001 aacgattaaa gcagatttct gctttggaaa aaattgctgt ggcaagcgtg gcgattgcta
     3061 ttgttgcttt atgtgtttta acagttatgc tgcgcacaaa tatcagcgga gctgaaaaag
     3121 aaatcacgtc aatacaaaca gaaatcaatg ataaaaagca agaaaaaacg agtttagaac
     3181 aagaaaaaaa cgaactttct cgtactgaac ggattaaaca aatcgcagaa gaaaaaggat
     3241 tgtctattaa tgacgacaat ttaaggataa ggaaagtgaa gtaaatgagt cttaaaaata
     3301 aaattcggcg gtttatggaa aagaaaaatc taaatccgat gaacaatcgc aaaaaagtag
     3361 gtatcatttt atttgctacg agtattggat tgttcttttt atttgccgtc cgtttctcgt
     3421 atatcgttat tggaggtcat gttgctggta cctcattagc tgaaaaaaca aaacagttgt
     3481 accaaggaag tgaagtagta aaagcaaaaa gaggaacgat ttatgatcgt aacggtgtgg
     3541 cgctcgcaga agatgcctcc tcttattcaa ttaaagcgat actctcaaaa acatatacct
     3601 ctggggataa aaaactgtat gttgaagaaa agaattttga taaaatagca gaaatcctgc
     3661 ataagaatct ttctatagac aaaaaagatg cactgaatat tttagaggac ggcgcaaaaa
     3721 aagagctgta tcaagttgaa tttggtagct atgggaaaaa tatctcccaa gaaaccaagc
     3781 aaaacatcga agcggacatg aaaaaagaag gtgtcgctgg tctttatttt gtcgaccatc
     3841 aggctcggat gtatccaaat ggcgtctttt cttctcattt tattggatac gcagttccag
     3901 acaaagatga gaatggctta gttggtaaac taggtttgga gtctgcttac aatgatatct
     3961 tgagcggtaa agatggtaag attatttatc aaaaagataa ttttcaaaat cctctgccag
     4021 gtacagtggc agaagaagaa aaagctgtcg acggacaaga tatctacacg actttagaca
     4081 gcagactaca aagttattta gaaacactga tggatcaagt aaatgaagaa tatcagccag
     4141 aagaattgac agcagtcctg atgaaagcaa aaaccggaga aatcttggca atgggacaac
     4201 gacctacttt caatcctgaa acaatggaag gattgactgg aaaagatgct atctggcgta
     4261 atttcttggt acaagatagt tatgaaccag gatcaaccat gaaagttttc actactgcag
     4321 ctgctatcga agaaggagaa ttcaacgaga atgaaacctt ccaatctgga aaaatccaag
     4381 tagaagatgc tacgatcaat gaccatgact ttggtgaaaa aggtgtgctg accatgcgtc
     4441 aagctctttc atggtcaagt aacgtcggga tggtcatact ggaacagcga ttaggcggac
     4501 gatggtataa ctatttacaa aaactgggat ttggacaaag tactcattct ggattagatg
     4561 atgaagtaaa cggtgcttta cctacattaa atattgtcga ccgagcaatg agtgcttatg
     4621 gacaagcggt aggtgtgacg aatttccaaa tgatgaaagc tttcacttct attgcgaata
     4681 acggtacaat gattcaacct cgatatatca gcaaagtggt ggatccccaa actggagaag
     4741 agcgaacaac tcaaacagaa gttctagggc aacctttttc aaaagaaaca acagaaaaag
     4801 tccgtgaata tatgagagat gttgtcgaaa gcgaaaacta cggtagtgct tatggtgtat
     4861 atagtgtacc tggatacaat gtatcggcaa aaaccggaac agcccaaatc gcttctgata
     4921 cagggggata tcaaacagga gatacagcct acctgtattc gattgtggag atggttcctt
     4981 ctgaagatcc agactatgtc ttgtatctaa caatgaaaca ccctaagaca tatgatcgaa
     5041 tggcattggc taaaatcgca aatccattga tgaaacgggc aatggatttt aaagaaactg
     5101 aagaagattc agatacagaa acaaaaacag aaaaagtatc cgtagccgat tatcgtaatc
     5161 ttgaagcgga cgttgcagca gctgatgctc aaaaaagtgg actgcaacct gtagtgatcg
     5221 gtaatggtaa aaaagtacaa aaacaatcta ctgccaacgg tgatcagttg atctctggag
     5281 aaaaactgat cctatatact ggtggtgata agctgatgcc tgacgtaaca ggatggtcaa
     5341 aagcagatat catgaagctg gggaaaatcc tcggtattga agttagtttt gatggagatg
     5401 gttattgtgt caaacaagaa cttgctccat atgaaaaaat cactgaagac aaacttagtt
     5461 ttactttaga agaataagaa gagaaatagg agagaaaaga gcatggaatg gacacaagca
     5521 ttgattccca ttgtcagcag ttgtgcaatg acaattgccg caatgccgct atttattggt
     5581 tattttcaaa tgaaaaagca aggtcaggcg attcgtgagg agggaccaaa gtggcacaat
     5641 agcaaagccg gaactcctac aatgggcggc ttagtgtttc tgatcggctc tattttgaca
     5701 ggaatttggg ttggagcttg gcaaaaacag ctaactccta ctcttttcat cttgcttttt
     5761 gtattagcgt tatacggagt aatcggcttt cttgatgatt ttataaaaat attcaagaaa
     5821 agaaacatgg gactgaactc gaagcagaaa ttgattggac agattctagg gggaatcatc
     5881 ttttatcttg tttaccgttc tgaaggttat ccaggtgtat tgaatttctt cggactagat
     5941 ctacctttag gaatcattta tggtattttc gctctcttct ggcttgttgg attttcaaat
     6001 gcagtaaatc tgacagatgg catcgatgga ttagttgctg gcttaggaag tatctctttt
     6061 gcagcttacg gtctaattgc ttggcatcag catcagtatg atgtattaat catttgctta
     6121 agtgttttag gaggtttact gggtttcttc gtctacaaca gaaaacctgc caagattttt
     6181 atgggagatg tcggttcatt agcgttgggc ggacttttag cggcaatttc tataatgcta
     6241 aaccaagaat ggacattgct tttgattggt ttgatctatg ttatggaaac agcaagtgtg
     6301 atgcttcaag ttacttcctt taagcttaca ggaaaacgaa tttttaaaat gtctccaatt
     6361 catcatcact ttgaaatgtg cggatggtcg gagtggaaga ttgatacagt tttttggttg
     6421 atcagcattg tgacttcgtt gatcacatta tggatcgttt ggtaggagat gacgggaaat
     6481 gaaaaaaata tcaacatatg aaaataagaa agtgcttgtc ttaggactcg caaaaagcgg
     6541 agtaagtgcg gccaaattat tacatgaatt gggcgcactt gtcaccgtta atgatggaaa
     6601 accttttgac gaaaatccgg aagcacaaga gctgctttct ttagggataa aagtaataac
     6661 aggtagtcat ccaatcgaat tgttggatga agaattttca ttgatggtca aaaatccagg
     6721 gattccctac agtcatcctt tagtagcaaa agcccaagaa atgggtattc cggtaattac
     6781 ggaagttgag ctagcttacg aagtagcgga atgcccaatt attgggatta caggaacgaa
     6841 cggaaaaaca acgacaacaa cgatgacagg actactactg aatgcaggag cagatcaagg
     6901 aattgcacgt ttagcgggta atattgggta tccagcaagt ggtgtagcgc aagaagcaaa
     6961 atcagaagat aaaattgtga tggaattgtc tagcttccaa ctcatgggaa tcacagattt
     7021 ccgccctcat atagcggtga ttaccaatat ctatgaagca catattgatt atcatggtac
     7081 aagaaaagaa tatgtcaaag ctaaatggaa ccttcaaaaa aacatgacag aaaaagatta
     7141 tctgatcctt aactggaatc agtcagaact acaagaatta gcgcaaagaa caaaagcacg
     7201 cgtactgcct ttctcgacaa aagaagtgtt ggaagacggt gtgtatgctg acgattactc
     7261 aatatactat aaaaaagaaa aaataatgga aatatctgaa cttggcgtac caggtaagca
     7321 taatgtagaa aatgcactag ctgctatttc tgtagcaaaa ttgtatggta tatcaaatga
     7381 agctatacga gaaacgttgc attttttcca tggcgtacca catcgtacgc aatatgtagg
     7441 agaaatccaa ggcagaaaat tttataatga ttcaaaagca accaatattt tagcgactaa
     7501 aatggctcta agtggatttg aaacgtctaa ggtcgtgtta ttggctggcg gattagacag
     7561 aggaaataca tttgatgaat taattccttc attaaaagga atcaaagcaa tggtcgtatt
     7621 tggccaaaca aaagaaaagt tgatggatgc tggaaaaaaa gcaggcatcg agacaatagt
     7681 aacagccgat tctgtagaac aagcagttcc tttagcatta gaaaacagta cagatggtga
     7741 tgtagtttta ttatcaccag cgaatgccag ctgggatcaa tacccaaatt ttgaaactag
     7801 aggaaacaga ttcatggaag ctgtgaaccg attaaaatag aaaaagtaga agcgagcgat
     7861 aaaaaatgaa aattttggtt acaggcggag gaacaggggg acatatttat ccagctcttg
     7921 cctttgtcaa ttatgtaaag actcaagaac cgaatgctga attcatgtat gtgggagcaa
     7981 aacgaggtct agaaaacaaa atcgtccctg atacaggaat gcctttccat accttggaga
     8041 ttcaaggatt taaacgaaaa atttccatgc ataacatcaa gacggtccga ttgtttctta
     8101 agagtatccg tcaagcaaaa aaaatcctca gtgattttca accagatatc gttatcggta
     8161 ctggaggata tgtttccgga gcggtagtgt acgctgcagc caaaatgggt attccaacag
     8221 ttatccatga acaaaacagt gtaccaggtg ttaccaataa atttttaagc cgatatgtgg
     8281 atcggatcgc tctttcattt aaagatgcgg cttccttttt tcctgaaaac aaagcagttc
     8341 ttgtaggtaa tcctcgagca caagaagtag cagatactaa aaaatcagat attttgaaaa
     8401 catttgattt ggatccagaa aagaaaacag tcttgatttt tggcggtagt caaggagcac
     8461 ttaaaatcaa tcaagcagta tcagtttttt taagtgaata tattccttct tcttaccaag
     8521 ttttgtatgc ttcaggagat agatattatg aagagatcct aaataaaata aatcctgaaa
     8581 tacaaaatat tagtgtccag ccttatatca aaaatatggc agaggtcatg gcttccagtg
     8641 atctgctggt ggggcgtgct ggtgcaactt cgatcgcaga attcacagct ctggggttac
     8701 cggcagtgtt ggttcccagc ccatatgtta cgaatgatca tcagactaaa aatgcaatga
     8761 gtcttgttca cgcaggagca gcaaaaatga ttgcagataa tgaactaaca ggtgaatcac
     8821 taagtcagac agtcaacgaa atcatgggtg atgaagaatt gcaaaagcaa atgtgccgag
     8881 cttctaaaga acaaggaatc cctgatgctt caaaacgtct ttatgactta gtaaaacaaa
     8941 taatcaaaaa ataaaggcgg tggtcttagt gagtaagaaa aaagaaccaa aaaaattgtc
     9001 tcatccgtct tctgatgaaa acaatttgac tccttggcaa aaggctaacc gaaaatatct
     9061 ggcagaacaa gagatgaaaa accaagagcc aaaaaaagaa gacataacat tagatacacc
     9121 cctttcagat tctgaagaag aaaaaacggt tcaagaggaa cagcaagaag aaagccagtc
     9181 cgagaaaaaa atcgaatttt ttgaagagat caagcaaaag aaaaacggtg gaccatataa
     9241 cggttctttt ttgaaccggc tgcccaattt aaaaagtcaa cggcacaaag tactatttcg
     9301 tcggttagct ttgatcatca ctgtattggg tataccgctg atttttttga tctattatgt
     9361 ttctccttat agcaaattac aagcagttgc agtatcaggc aataagacag tcaacagcca
     9421 agaaatcatc tctgatacaa aattgtcatt aggagaaaat gtttggggac agtattttca
     9481 tcgatctact tatatcgatc gccttaaaaa agcacagcca agaatcgaaa cagcaaatat
     9541 acatttcaaa gggatgaatg aattcgattt ggatgtaaca gaatataaag agattgcttt
     9601 gatcgcaaaa aacaatcaat actacccagt gattgaaaat ggaacagtat tagatgaaaa
     9661 agtagcaaat cctacaaaaa atctccctat cttggaagag ttcaaagact ctgcaaaaat
     9721 caaagaatta acaaagcaat acaatcagtt atcatcagaa ttacaaaaag caatttctga
     9781 aatcaagtac acgccaagag caagcaataa aaatctgatc caattgaata tgaatgacgg
     9841 caatcaagtt attgtaaata tcaataatct tgcgaaccaa atgaaatatt attcgcaagt
     9901 agccaaagat atggatgaaa aaggtgtgat cgacatggaa gttggtatct tctcgcatcc
     9961 ttacggtagc actcaagaaa cggaagaatc gggccaatcg gaagaaacaa ctgaaagtga
    10021 agaaaatgcg gatcaaacaa acgaatcaag tgaagaggca gaaacgcaaa aagcacaaac
    10081 acctggatcg tctagcacaa acggatcatc tgattcaaat gattcaagtg aaacaagtca
    10141 aatagaagat aatccaagta caactccgtc aagtttaaat gaaaattgat aaaacaactt
    10201 taaaaagtaa gaatgtactt tctaaaaacc agtaatttat ggtagaattg gaagcagtga
    10261 atatatctat taataagtat attttaaaac ggacgctagt tgttcgcttg tatatggaat
    10321 agtaagtagg agggaatccc attcatggca aaaacaggaa tgtatgtagg ccttgatatt
    10381 ggaacgacat ctgttaaagt tgtcgtggct gaatatatcg acagccaaat gaatattatt
    10441 ggagtaggaa acgcaaaatc agaagggatt aaccgaggca ttatcgttga tatcgataaa
    10501 acggtccaag cgatacaacg agcagtacga caagcagaag aaaaagcagg tatccagatc
    10561 aaaggcgtaa gtgtcggttt gccagcaaac atgcttgaag tagaaaattg ccagggaatg
    10621 attgcagtta acggagattc aaaggaaatc accgatgaag atgtcagaaa tgtggcttca
    10681 gctgcccttg ttcgttcaat acctcctgaa cgtcaaatcg tgtcaatatt gccacaagat
    10741 tttactgtcg atgggttcga gggaatcaaa gatcctcgtg gaatgatcgg cgtaagatta
    10801 gaaatgtacg gtctgttgtt tacaggacct aaaacgatca tccataacat acgtaaatgc
    10861 gtggaaaatg ccggattaat cgtcaacgaa atggtgatta ctcctttagc gctgactgaa
    10921 tcaattcttt ctgacggaga aaaagatttt ggtacgatcg tcattgatat gggtggcggc
    10981 caaacaacaa cggctgttat gcatgataag caattgaagt ttaccaatct tgaccaagaa
    11041 ggtggcgaat ttgtcactaa agatatctct attgtattaa atacgtcatt taacaatgca
    11101 gaagcgttga aaataaacta cggggatgca tacccagaac ggacatcacc agatgaagaa
    11161 tttccagtag atgtgattgg tcagtcagaa ccagtgaaag tcgatgaacg ctacttgtca
    11221 gaaattattt cagctcgaat ggaacagatt ttcaacaaag caaaagatgc attggaccaa
    11281 atcgaagcat tagagttgcc aggtggcgtc gtattgacag gcggagctgc tagtcttcct
    11341 ggtgttgtgg acttggcaca agaaatcttc ggcgtaaatg taaaattgta tgttccaaat
    11401 cacatggggc tgagaaaccc ggtatttaca aatgtaataa gtatcgtgga ttattcagca
    11461 aacttgagtg aagtgtatca attggcaaaa attgctgtta cgggtgaaac ctcagcagct
    11521 cgtcaaatgg tagttgaaca agaaacaaca aacacatatg agagctatga agcacctgaa
    11581 gaaacaatct acgatgagcc ggaaccaaaa gagtccggag aaaatgtaaa aaataaaatc
    11641 aagggtttct ttacaaatat ttttgattaa ttcatcctgg gaggaataag atatggaatt
    11701 ctcaattgat aataatatca atgacggcgc agtaatcaaa gtcatcggag tcggtggtgg
    11761 cggtggaaat gctgtaaacc gaatgattga agaaaacgtt aaaggtgttg aattcattac
    11821 agccaacaca gacgtgcaag cattaaaaaa ttcaaaagct gaaacagtta tccaattagg
    11881 ccccaaatat actcgtggtt taggtgctgg ttctcagcca gaagttggac aaaaagcggc
    11941 agaagaaagt gaacaatcct tacgcgaagc tttagacggt gcagatatga ttttcatcac
    12001 tgcaggaatg ggtggaggaa ccggtacagg tgctgcacca atcgttgcag gtatcgcgaa
    12061 agaattgggc gcattgactg ttggtgtcgt gacacgtcca ttcacttttg aaggaccgaa
    12121 acgtggccgt tttgctgcag aaggtatcgc tcgtttgaaa gaaaatgtgg atacattatt
    12181 aattatctca aataaccgtt tattagaagt tgtagataaa aagacaccga tgcttgaagc
    12241 tttccgtgaa gcagataatg ttttacgaca aggtgtacaa ggtatctctg atttgatcac
    12301 agcgccaggt tacgttaacc ttgactttgc tgacgtgaaa acagtgatgg aaaaccaagg
    12361 tacagcattg atggggatcg gtgtggctag tggagaagat cgcgtagtag aagcaacgaa
    12421 aaaagcaatc tcctctccat tgcttgaaac atctattgat ggagctgaac aagtacttct
    12481 taacatcaca ggcggtttgg atatgacatt gttcgaagca caagatgctt cagatatcgt
    12541 agcaaatgca gcaactggcg atgtaaatat cattctaggt acatctatca atgaagaaat
    12601 gggcgatgaa atccgtgtga cggtcatcgc aacaggtatc gatgaatcaa aaaaggaacg
    12661 caagtctagc cgaccagcta gacaagcaca aatgcaatca cctgctcaaa agactgtatt
    12721 agatatggat caagctaaac caacttcttc agaagaagaa aacagttttg gcgattggga
    12781 tatcagacgt gaacaaaatg ttcgtcctag agttgatgat tccaattttg acaatatcga
    12841 aaaaaaagaa tttgatacat tcaaccgcga agaaacaaaa tctcatggcg atgatgaatt
    12901 aaatacgcca ccgtttttcc gtcgtaaaaa ataaaggaga ggaagagcac atgattgctg
    12961 acaacttgca gaaaatcaag caagaaattc aggattcgtg tgctcttgtt catcgtgatc
    13021 cgaaagaagt tacattagta gctgtaacaa aatctgttga atccgctcaa gctgaagaat
    13081 tggttagagc tggcgttatg aattgtgcag aaaaccgagt agataaatta ttagaaaaga
    13141 aacaagattt atttgatttt cctgaaataa agtggcattt aattggtaat ttacagcgca
    13201 gaaaggtaaa attgattgta aatgaaattg attactttca tgcgttggac agtttaagat
    13261 tagcagaaga aatccagaag cggttagaga aagaattatc ctgttttatt gaagtaaatg
    13321 tttctggtga ggaatcaaaa catggaattt caccagatga gcttttaccg tttgtggaat
    13381 ctttagctgc ctgcacaaaa atcaaggttg ttgggttgat gactatggcg cctaaagaag
    13441 cttctgatga gcaaatccat aaagtgtttg gtacgctgaa agaattgcgt gatcttgttc
    13501 aagcaaaagg ttatgcccat gcaccatgta gtgaattaag tatggggatg agtcaagact
    13561 ttcaaattgc gattgaagaa ggtgcaacat ttatccgtgt aggaacagcg ctattcaaag
    13621 acgaataaag gaggaacaaa aatgccgctt ttaaacagag gagcaattgc taattttttc
    13681 ggattagctg atgaggaaga gtacgaatac caagattatc ctgaaacaac aaaaaaggct
    13741 gtacagccaa ctaaaaaaaa tacaacacag aatcaatcaa ctcattctgt atctgctgcg
    13801 aatactcatg aaaaacaaaa aacggcgact tcacgtcctg taacgcatga aagtattcag
    13861 ccggctgaaa agaaaaaagt aattgaacta catcaatcac ctacaaaaac tgtagcgaaa
    13921 gaaagaacag cttcaagaac ctctacacaa cctaaagcaa atcttgctgg aaaaatcact
    13981 gtaatggaac caagagctta ttctgaagct atggcgattg ctaaacgaat cattgctgga
    14041 gaagcaacct tagtgaattt tcatttagta gaagaaaaac aagcgagaag aatcgttgat
    14101 tttctaacag gaacagttta tgcactagat ggagatatca aacgtgttgg agatgagatt
    14161 tttctttgta caccgactgg gatggagatt gacagttcaa ccgctcaatc ttttgcagat
    14221 gcgaatttgt ttgatctgta agaggaggaa ctacgattta tactattgca ctattacttc
    14281 atttacttca acgggcagcc tatttctata gcattatctt gatggtatat gcattgctct
    14341 cttggtttcc aggcgggtat caatcagggc taggacgatt attagctaag atctgcgaac
    14401 cgtatatcag tttgttcgat cgtctgcctt tgaggattgg acccttggat ttcacaattt
    14461 taggggcaat cctgatcttg aacttagccg tacaaggttt agcacagatc gttatatgga
    14521 taactgtcca tttagtttat tgattgaagc aacaaaatct ttattctcag aatagatagg
    14581 aggggaaaat tttggatgca aatgtatacc agcactttcg ggcagatgaa cgtacattta
    14641 tcgattcggt aggcgattgg attgaacagg ttcaaggaca atatgcaccc tatctgaccg
    14701 aatttcttga cccaagacaa tcctatattt tagaaacact gattcgacaa agcagtgatt
    14761 tgcgtttcat gttttatggc ggatatgaac aggcagaaag aaaaagatgt ttgattttcc
    14821 ccgattatta cgaacctgta gaggaagatt ttgaaacagc attgtatgaa atccattatc
    14881 ctagcaaatt tgccagccta agtcatggga aaatccttgg aactttagtg ggaacgggga
    14941 tcaaacgctc ttactttggc gatatcatct cggacggtga tcgctggcaa gtatttattg
    15001 caaatgaggt ggatcatttt gttgctgcac aagtaacaaa gattggaaag gttgctgtac
    15061 gcttggaacc aatcaaatac acagaaatga ttatgccgaa agatagctgg acacaagaaa
    15121 gaggaacagt tagttccatg cgactagaca gtgtgatctc tgagatttat aatatttcca
    15181 gacagcggtc caagcagctg atcgaagctg gtaaagtaaa agtgaactgg acagaaaata
    15241 caagacctga ttttgtactt gaactattag atattatttc agtcagaggt tatggcagag
    15301 tccagatcca agaacttgag gggaagacga aaaaagaaaa gtacagggta ctgttcggtg
    15361 tattacgtaa ataaaataaa aaggtggttt actcatggct ttaactccat tagatatcca
    15421 aaataagaca ttcccgacaa aaatgcgggg atataatcaa gacgaagtag atgatttctt
    15481 agatttagtt gttcgtgact atgaggaatt gactcaaaga aatcgagaat tagaaaaagc
    15541 agtcaaacat tctgaagaaa aacttgagta cttcaatgaa ttaaaagatg ctttgaacca
    15601 atcaatcatc gtagctcaag atacggctga taaagtaaaa acaagtgcaa gcaaggaatc
    15661 cgaagtgatc gttacttctg cacaaaacaa agcagatgag ttagttgcga acgctgaaaa
    15721 acgtgcacat caattaacaa ctgatgcaga agaaaaagca agaaaaatct tgacagatgc
    15781 aacagaaaaa gcaagacagc ttgcgacaga aactgaagat cttaagaaaa aaacacgagt
    15841 attccatcaa cgtatcagct tgatgcttga gtctcaatta gaacaagtga aaagtccgga
    15901 atgggatgaa attttacaac cattctccag ctacgtgact gacagccatg aagtgatcaa
    15961 agaagtttta gcaaaacagc ttgacaatga aaatgatact gatgtaaact cagacacagg
    16021 agtcatagaa gcacctatga cggcatttga tacacaggct attgatatct cgatcgtgcc
    16081 tggtgaaaat gaaaacgagt agaacagaaa agcactttgt tattcttaaa gcgagccgat
    16141 gagagtggaa gttcggtaag acactgcatg gtgaaagatc ctctacttga gacctgcttt
    16201 tccgaaatta gagtaagaag cagcggctga cctcgttatt ggtcacagag agtttgcact
    16261 agatagatgc aactaaattt gggtggtacc acggcatgtt cgtcccttgc ggctgaacat
    16321 gcttttttgt gtccggaaaa caaataaagg agtgtatggt tgaatgaaaa tgaaagaaac
    16381 cttgcaatta ggaaaaacaa aattccctat gcgtggtaat ttgccaaacc gagaaggcga
    16441 gtggcaaaaa gaatgggaag aaaatcgaat ctaccaaaaa agacaagagt tgaacgaagg
    16501 aaaacctagc tttgttcttc atgatggacc tccatatgcc aatggtaata tccatttagg
    16561 acattcattg aataaaatca gtaaagacat tatcattcgt tcaaaatcaa tgtctggcta
    16621 tcgtgcacca tatgttccag gatgggatac acatggattg ccgattgaac aagtattggc
    16681 taataaaggc gtgaaacgta aagaaatgtc catggcagaa tacttggaaa aatgtcgtga
    16741 atatgcactt tcccaagtag ataagcaacg agcagatttc aaacgcctag gagttgcagg
    16801 agattgggaa catccttatg ttacattaga tccttcttat gaagctgcac aagtacgcgt
    16861 atttggtaaa atggctgaaa aaggctatat ttacaaagga ttgaaaccaa tttactggtc
    16921 tccgtcaagt gagtcttctt tagcggaagc tgaaattgaa tataaagatg taaaatctcc
    16981 atctattttt gtagctttca atgtcaaaga cggcaaagat attcttgatg aagatacagc
    17041 ttttgtcatt tggacgacaa caccatggac attgccagca aaccaaggta ttgctgtaaa
    17101 tccaaaattt acgtatgtat tggtggaagc cgatggccgt aagtttgtcg tagcgaaaga
    17161 tttgctagaa acagtccaat cagaaatcgg ttgggaaaat gtaacagttc taaaagaatt
    17221 tgctggacaa gaaatggaat atatgactgc aagtcatcca ttctatgaac gtgaatcact
    17281 tgtgatttta ggcgatcatg ttactttaga cgctggtact ggattagtcc atactgctcc
    17341 aggacatggg gaagatgact atatcgctgg tagcaaatat aaactatctg tagtgtcacc
    17401 tgtagactca aaaggattgt ttacagaaga agcacctgga tttgaaggta tcttttatga
    17461 caaagcaaat cctatgatca ctgatctatt aaaagaaaaa ggagctttgc tgaagctaga
    17521 tttctttact catagttatc ctcacgattg gcggacgaaa aagcctgtga tctatcgggc
    17581 aactccacaa tggtttgcat ctatcgataa attccgtcag aatattttgg atgaagtaga
    17641 aaaagtagag tgggttatcc catggggtaa aacacgtttg tataatatga tccgtgaccg
    17701 cggcgattgg gtaatttccc gtcagcgtgc atggggagta ccacttccga ttttctatgc
    17761 tgaaaatgga gaagcaatca tcacaccaga aacaatcgaa catgtggcaa aattatttgc
    17821 tgaacatgga tcaattatct ggtttgaaaa agaagcgaaa gaacttcttc ctgaaggatt
    17881 tacccaccca ggttctccta atggcgaatt tacaaaagaa aaagatatca tggatgtctg
    17941 gtttgattct ggttcttctc atgaagctgt tttacgtcag cgaccagaat tatcattccc
    18001 agcagatatg tatttagaag gatcagacca atatcgtggc tggttcaact caagtatcac
    18061 gactagtgtg gctatcaatg gtgtagcacc atacaaatca gttatttctc aaggatttgc
    18121 tttagatggt gaaggccgta agatgagtaa atctttagga aacatcattg caccagaaaa
    18181 agtgatcaaa caatttggtg cagatatcct tcgcttatgg gtatctagtg tagattatga
    18241 agcagatgtt cgtgtttcta tggatatctt aagtcaagtg gcagaagtat atcgtaaaat
    18301 cagaaatacg atgcgtttct tattagcgaa tacagaagat ttcgatccta aaaaagatac
    18361 tgtttcgtac aatgatttac gttctgtaga caaatatatg accgttcgat tgaaccaagt
    18421 aatcaaagaa atccgagaag aagggtacga caaatataac ttcatgcata tttaccgtac
    18481 agttatgaac ttcttgacgg ttgatctatc gtcattctac ctggattttg ctaaagatgt
    18541 agtttatatt gaagcagaag atgattatca acgtcgttgc atgcaaactg ttttctatca
    18601 aacagctgta gctttgacaa aattattgac tcctatcatt ccgcatacag cagaagaaat
    18661 ctggtcattc ctgaaagaag aagaggagta cgttcagtta agcgagtttc ctggttatga
    18721 agagtttgca aaccaagaag aattgatgga tacctggact gctttcatgg acttccgtga
    18781 taatgtctta aaagcattgg aagaagcaag aaacagcaaa ttgattggta aatctttgga
    18841 agcaaaacta actgtttatc caaaacaaca agttcgtgaa atgttaaaag ctttggatgc
    18901 agatattgca caattattga tcgtttcacc agactacttt gaagttatgg cagcagatga
    18961 acaagtgcca gataacgcta tggtatttga tgatgttgct attacagtgg aaaaagcaga
    19021 cggggaaact tgcgatcgct gtcgccaagt tcgtaaagat gtaggagtag atgaaaaact
    19081 tcctcatcta tgcggtcgtt gtgcaaaaat cgttgaagac ttctatcctg aagctgtagc
    19141 tgaaggattc gaagaaaagt aaaagggaaa agggggtgtg acatgttctt tgtcacaccc
    19201 ccttttgtta tcaatcgttt aattttccac gttcacgata ccagttatct ggttgccaga
    19261 tccattcgaa tccgtctttt tcaagtagtt cgaaagctgc tttaggtccc attgatccag
    19321 ctttgtagtt gggaaaatcc ggttgtgttt ggtcccaagc ttttcgaatg acatccacga
    19381 tatgccaaga ttgagcgact tcttcccaat gagagaagtt cgttccatca ccattcaacg
    19441 catctaatag taatttttcg taagcttctg ggctattttc aaccatttct gcactatttc
    19501 taaattccaa tttgattggt tccgtttcaa atccttgccc tacttctttc ccattcaagg
    19561 ataaagaaaa tccttcagtt ggctgaatat agatcgttag aacattaggt ggaagtgtcg
    19621 tatcgtcaca tggttcatcg acagatgttt tgaatacatt aacaggaact tgtttgaata
    19681 cgatgttgat ccgagtccct ttttcagtca aacgtttgcc tgtacgtaca tagaaaggaa
    19741 cacctgacca acggaagtta tcgatagtga atttgcctgc gacgaatgtt tcagtctctg
    19801 attgagcatc cactttgtct tcttcgcgat agcccttgaa ttgtacacca tccaattcac
    19861 cttgagcata ttgcccgcga acgaagtttt ctaacacttc ttcttcgtta taaatgcgga
    19921 tagctttcaa tgctttgatc ttttctgtac ggatttcttt ttcggaaaat gctactggcg
    19981 gttccattgc aagtaatgct acaacctgta aaatatgatt ttgcaccatg tctttaagtg
    20041 cgccactatg atcgtagtag cccccgcgat cttctacacc gaggttttcg ccaaaagtaa
    20101 tttggatatt gtcgatatag cgattgttcc attgagcctc aaaaatatta ttggcaaaac
    20161 ggatagctga gatgttttgg atcatttctt ttcctaaata atgatcaatc ctgaaaatat
    20221 cttgttctgg gaatacttct ctgatttgct ggttcaattc aaaagcagac tggtaatcag
    20281 aaccgaacgg tttttctatg atcaaacgat tgaagccatt ttttgtcata atattttgtg
    20341 atttcaaatg agaaacgatc gttccaaaaa attgaggtgc catagccaaa taatagacac
    20401 ggttaccgtt taattgatag tgtccatcta atcggtcaga caattctttt aatgtctgat
    20461 aatgcgttga atcatttaca tcatgggatt gatagtaaaa atggcttgca aaggtagttg
    20521 cttcttcatc tgaaggattc aatgcacgga ttgtttcttt gacaacttca cggtagtgct
    20581 catcgctcca gggacggcga gcggttccga ttacagcaaa atgctcgcct aaatttcctt
    20641 ttctgtaaag gcggaacaaa gacgggtaca atttacgctg ggctaggtca cctgtaccgc
    20701 cgaatatcgt aaacaataca tttttttcat tagacatgtg gatacactcc tttatatttt
    20761 atcgacaaaa atcgtgctgg ccgccttaaa gctgacgggg attttctttc tatcattttg
    20821 gatagtgatc ggtccttcat aagctgcgat gtcaacgatc tcatattctt cgttgatatt
    20881 caggtcaata gtgactaagt aatccaacaa ttctttttca tcaagcactc gtgcgatacg
    20941 cacttttgta ccgacaggat aggactccaa tgtttgtcgg cgttcttcat ggacaacttc
    21001 ctctttttta ggaatcgatc ctccatgagg acaatgttca ggatgattca aatagttttc
    21061 taaatgatct gcaagatgtt ccgaagtcac atgttccaat acttcagcat catcatggac
    21121 ttcattccag ctatagtcta aatgttcaac taaaaaaact tcccataagc gatgtttgcg
    21181 aatcagactg ctagcttttt gcagtccgct tgcagtcaat tgtacacctt gataagggga
    21241 atgttctaca agctcttctt tcacaagttt agaaatcatt tcactgacag atgcagctga
    21301 gacatctaga ctagatacga tttgtttatt gttgactttc gttgtatctc cacctagttc
    21361 taaaatgatt ttcaaataat cttctcgatt tggtgtcata ttcgatcatc ctttcatggt
    21421 aaaaaaccat cattagtaag tgtaacaaaa aaaacgttaa ttgactattt ttctaaataa
    21481 aaaacaaagg atttttagac gtttttacaa caaaaaacga aagatgatag agaagactca
    21541 ttctttcgtt tataaaggat atatatatac attgggaggg atctattttt cagataacaa
    21601 cttatatgaa gtgtctgcag attcgtcata aagagtttgt tcgggataag aaaagataag
    21661 ataaaaacca tactgatcac gtacgactaa acgatattca tctatttcta ccacagatgt
    21721 gccaagagac tgaccgttga tcaaaaacgt gtaatcagat gtaatctgta attgttgttt
    21781 ttgctggcta tcactaaaga accatgtacc ttgatacttt gagagtcctt ctgacttttc
    21841 cgcttgtttt ttctttttca agtaaataaa acttgagaga acggtaatga gtgaaccaag
    21901 aaaatagatc atttttttta tcaccaaatc actcctttat gagaaaataa tcgcatagac
    21961 atattctttc ttctttattt cattgtaccg aataaaagct aaaatttctc taagactttc
    22021 gactggtttt tttactgttt ttctacaaat tatgatagga tacatagtag gaagaaaggt
    22081 gacataattt gaagtatcag caagtggaaa tagctttttt tattgaccgc ccgaatcggt
    22141 ttatagcaca ttgtatgaaa aaagacggag aaataattat tgcgcatgtc aaaaatacag
    22201 gtagaggaaa agaggtcctg ataccaggcg ctgaagtggc tattgtattt gctcctggac
    22261 ctaaacggaa aaccgcctat gatctgattg ctgtaaaaaa gaagggtgac tggtttaata
    22321 tcgatagtca attgcctaat cggctggcaa ttgatggtat tttagacggc acgatccttt
    22381 taccaggatt aactggtcca tttacggtat acaagcgtga agtaacttat cttcactcca
    22441 aatttgatat ttatttagag acggtggtcg gacaaaaagc atttgttgaa gtcaaaggta
    22501 tgacacttga aaataaagcg attggtgctt ttcctgatgc gcccacactc agaggattga
    22561 aacatatagg agaattaacg tatgccgcac aagatggtta tgccgcttat gtcttgttta
    22621 ttgctcagtt cgaacatctt catctggcaa cgatccatga agaaatgcaa ccagcactag
    22681 ctgatatggt tcgacatgcg cagcaaagcg gagttcaaat cctcgcctat aattgtcaag
    22741 tatcggcaga tgaggtaact gtcaagcagg ccattccatt tgatgtagat atcccttttg
    22801 aagatcctat acaatagaaa gaaggtaaaa taatgatcaa cttaggtatt atcggaacaa
    22861 attggattac tcatcaattt gtccaagcag ctttaagcac aaaaaaatat gaattgacag
    22921 cggtatattc tagacatttg gaaaaagcac aggaatttgg ttctcattat gaaggggata
    22981 tcgaattcgc aacagatttg aagacttttt tcaatattac tcatatggac accatttata
    23041 ttgcttctcc gaatagtctt cactttagtc aagctaagca agcaattttg gcaggaaaaa
    23101 atgtgatagt tgaaaagcca gctttttcga cgccaaaaga aatggatgaa atcatccatt
    23161 tggcaaatga acacaatgtg tatttttttg aagcagcaag aaatatccat gaatcaggtt
    23221 ttaaaaagat tgccgattac ttaccattaa aagacgagat aatcggtgca aatttcagct
    23281 atatgaaata ttcttcgcgc tatgaccaag tattagatgg agaagaaccg aatatcttct
    23341 cgactcattt ctcaggtggt gcattgatgg atttaggtgt ttaccttgta tatgcagctg
    23401 ttgcttggtt tggaatgcca aaagaagtcc attatttccc aagaaagatt tctactggtg
    23461 tagatggtct tggatggggg atcttacgtt atgagaattt tgatgtatcg atccagccag
    23521 gtaaaatcgg tgattcttat ttaccgtcag agatttattt tgactcagga acgctagtga
    23581 tgaatggagt caatgcaatt gaacaagcac aatttcatga tcgcgcgcat aaagaaatca
    23641 ttgatttggc ggtaacagct gcagaaaatc caatggcaga tgaagcagag gattttgcca
    23701 atgtcatggc tcatccgaaa gatccagctt ggggattgtt gtatgaagag tggatcgagc
    23761 tagctagaaa tgtgaaccaa gtgatttatg atttaagaaa aaatggcggc atcaaattcg
    23821 atgcagataa tgaggaagat ttttaatgaa cgaatttgta caagtatttc ccgaaaattg
    23881 gcagaaaaaa tatgaggata aagggtttat ctcaccttct cttattcaac gagcagtttt
    23941 tcagccacta agtaataaac aaagtatagt agcggtttct cctacaggtt caggtaaaac
    24001 actggcttat ctttggcctc tactactaaa cgtggaacca ggtgaagcaa gtgcgttggt
    24061 catttttgct tcttctcaag aactagctat tcaagtagca gatgttgcac gtgaatgggg
    24121 aaaagacaaa gagttgaaag tccaatcttt ggtgggcgga gccaacgtca aacgtcagat
    24181 tgagggtttg aaggaaaaac cagaaatctt gattggtaca ccaggaagaa tattggaatt
    24241 gatgaaagca aaaaaaataa aagcacatca agtgaaaaca atggtatttg atgaagcaga
    24301 ccagctattt gacgctggga acagccaaat cattgatcaa attcttcatc aagctccaac
    24361 agagtatcag ctagcttttt tttcagcgac agcagatcgt tcccttgaaa gcattgaaaa
    24421 aatcactggg aaaacgtttg agacaattga cgtgacagca gaggacgatt ctcgaaaagg
    24481 actgagacat tactttttac gtgtaccgat acgaaagaaa gatgactact tgagacgtct
    24541 cacgcatata gaagattttc atggtctgat tttctttaat caactgactg aattaggcgt
    24601 aatggaagaa aaattgctgt atagaggtgt accggtagga agtctggcct ctgatcagaa
    24661 caagctactc cgaaaagcag cgctagaaca attcaaaaag aaaatggtca gagcactttt
    24721 gaccacagat gtggcggcta gaggtttaga tattacaggt cttccttatg tagtgaatgc
    24781 agaagttccg ttaagtgaag aagcttattt gcatcgttcg ggaagaactg gtcgaatggg
    24841 taatgaagga atagtaatta cactcgtaca agataataat ctaagagatt taaaacggct
    24901 tttacgtcca tcaaatataa cacttgaaga gattttttta tacggaggta agctgcaaac
    24961 tgagcagcca accaaagaag atgcagctcc tgcagtaaat aaaaagtatg cgaaaacttt
    25021 ttctggaaag gagcagaacc cagaatataa caaagaaaaa ataagaaaaa aagttaaaaa
    25081 taaatcaaaa aaagagagaa ataaaggagc aaggcgcaaa taagcgcctt tttatgctat
    25141 gattatgaaa acgggaacaa aattggttgc cagaggaggg gttatgtgaa agaacgtcaa
    25201 gaagagatct tgcagctatt gacagaaaac caacaaggat tgacagcaag tgatgtagct
    25261 gagcgcttaa ctatcgatcg aagcaatgca agccgatatt taagtgaact atacaaggcc
    25321 catcatattg taaaaaccgc tggccgacca gtcgtttact ctttgccaac ggaaaagtca
    25381 aaatctgatg aagtgcatgt cgactcttct acgcaagtga cttttgaaac actcgttgga
    25441 gaaaatgatt ctttaaaagt cagcatacag caggcaaaag ctgcgattct ttatccaccg
    25501 cgggggttgc atacgattat ttttggagaa actggtacag ggaagtcgat gtttgctgaa
    25561 tgtatgtatc attttgcaat cgattcagag atgctttctg cagatgcgcc atttgtttct
    25621 ttcaattgtg cggattatgc tcaaaatccg caactgctct ttggacacat ctttgggatc
    25681 aaaaaagggg cttacacagg agcagctcaa gatagtcccg gtctaatagc caaagcagac
    25741 ggcggtatat tgtttttaga tgagatccac cgtttaccgc cggaagggca ggaaatgctg
    25801 tttactttca ttgataaagg tatttaccgt ccgcttggag aaagtgcaca agtacatgaa
    25861 gcatctgttc agatcattgg ggcgacgact gaatcttcag aaagtttctt atctacgttc
    25921 aatcgacgga ttcctatggc aatcaccttg ccgaatcttg cttcacgttc actggatgag
    25981 cgttatgaaa tcatctctct ttttatcaaa caagaagcga atcgtttgaa tcaacgtatc
    26041 gatatcgaaa aagaagcgat tcttgccttc atgctttatg atgcggaagg aaatatcggt
    26101 caagtgaaac gagacttgaa actagtctgt gcaaaatctt ttttacatta ccgtactcat
    26161 catgagaaaa agctaatcat tcgaaaagaa gaactttccc ttcaagtaca aaaaggatta
    26221 ctgaaaatca aggaaatacc ggaacgtctc gaccgattca tggacagcaa aagtcagtat
    26281 ttgacatttg aaccaggatt tgctgatgtt gtctggtcac aagatccaga acgaaacatg
    26341 caggtctata acgatattga ggaaaaagtc acttctcttt ccgaaaccgg tgtggagaac
    26401 attgatctag agaccctcat ttcaaaagat gtggatgctt atttccagac atatgtcaaa
    26461 gaattgacta aaagttcgat tcccaaagat cttttgccag atgaaatctg gcggttaacc
    26521 aatcaattgt atgatgtggc tgaaaaacgg ttagaccgta tttataatga aaaagctcgt
    26581 tttgcttttg ctttgcatct gcaaagtaca ttggatcgtg tgagagaagg tcatatgatc
    26641 gtccacccag atttgaataa cgtacggaaa aattttaaga gggaattcca ggtagcaatc
    26701 gatctttcaa cgatcattga agaagaagaa caagttgaga ttccttttga tgaaatcggc
    26761 tttattagta tgtttctttc tatcaatcta ggagaaagtg agcctgttaa agaaaacaaa
    26821 gtagatgttc tcatattgat gcacggcaga cagactgctt caagcatgtt ggagatggca
    26881 caagaactat taggaacaaa agtagggaaa gcttttaata tgccactggt tatggaagtt
    26941 caaacaatgt atgaagaagt gttacaatat gtcaaaaact atcaagagca tttgacgaat
    27001 ggcctactct tgttaacaga tatgggatca ttaaacacct tcagtgattt gatttatgaa
    27061 gagactggca ttcggacgaa agctatcacg atgacaagta ccatgattgt gatagaagcg
    27121 atacggatgg caagtgttgg aagaagctta gaagatattt atcaaaatat ccagctttcc
    27181 tttgaatcga tcgtacgtga tcagttcaaa gcggaaaagt ctgaaacttt acagcgtaaa
    27241 aaagccgtaa tcgtgacatg ctttactggt gaaggagtag ctgccaaatt atatcagcgt
    27301 attatgccag tgattaatca aaataaggta gaactgatcc agatgcagtt tttagaacgt
    27361 gaatcattca aaaaacacat cgatgcctta ttggaagaat atgagatcaa agcaattgcg
    27421 ggaacagttg atgttgatta tcaaaatatc ccattttttt cagcctatga cgtttttgat
    27481 gatgaaaaac taaatatttt aaagcgtata gctgatgatg agatcccgac agctaaaatt
    27541 gtcgattcac ttgctggatc attaagcgat gtcttttcta ttgatgaact gatccgttca
    27601 ttgcaaaaga cagttcagca gatccagacc gatttgtcga ttatcgtgga acctggagta
    27661 gatactggaa tcgttatcca tttagccttc atgttagacg gattgatcaa acaagaaagc
    27721 catcggcaat ttgagaaact gtctattttc tcaaaaattt atcgtttgga aatggatatc
    27781 gttcgggcaa acttgatggc actagaacga aaatatcagg taaaaattcc agaagatgat
    27841 atcgcatttc ttacacaaat gtttcttgaa aataaaataa aaaaatgaac acactaatca
    27901 tactgtttac acactaaaca tctgtgtgcg cactataaaa aagagctaaa aagcatgaaa
    27961 acgctatttc agctcttttt tttattggca tgcttcttgc gttatataaa agtgtaaaaa
    28021 aataaaagga gtgttaaaaa tggcaaaaaa aacaatcatg ttagtttgtt cagcagggat
    28081 gagtacgagt ttattggtca caaaaatgca aaaagcagca gaagaaaaag ggatggaagc
    28141 cgatattttt gcggtctctg cctcagatgc agataataat ttagaatcta agaatgtcga
    28201 tgtattatta ttaggtcctc aagtacgttt catgaaagct caatttgaac aaaaacttgc
    28261 gcctaaaggt attccattag atgtcatcaa tatgcaagac tatggcatga tgaacggaga
    28321 aaaagttctt gcacaagcag aaaatctaat gaaataaatc aagtatgcag ttgggggtat
    28381 aacaacgtgg aagatcaaca aaatctagaa gccatcatgg ggttaatcat gtttggcggt
    28441 aatgcaaaga gcgatgcaat ggaagcgatt gcggctgcta aaatcggtga ttttgagtta
    28501 gcggatagga aaatcgctga tgcagaagaa tcacttatac aagcgcatca tgcacaaaca
    28561 gacatgttga cacaagaagc acaaggaaat catatgcaag tgacattatt gactgttcac
    28621 agtcaagatc acttaatgac atctattgcg tttactgatt tagcaaaaga aatcatcgaa
    28681 ctttatcgtc gcgtatacag cgaataaata caacttcttt tttgaacgga agaagaaaaa
    28741 tttttgaacg gattttttat tttgttataa ggagaactct ctttatataa aaaacttata
    28801 ggaggaagta aaaaatgaac ggactatcaa gttggatgga gaaatacatc ctgccggttg
    28861 ccgcaaaaat cggagcgcaa aaacatttag ttgctttgcg tgatgctttt atcggcacac
    28921 tgcccgcaac aatggcggga tcagtcgctg taatgatcaa tgcaattatt cgtgatttac
    28981 cgcaacagtt taacagtacc tatgctgaca gtttagcagc agacaaagga atctttgccg
    29041 tattgaatgt catcatcgga atcaatggtt ttgtctggaa cggtacacta gcaatcgccg
    29101 gattgatctt tgccttttct tgggggtata atcttgcccg agcttatgga gtaaatgatc
    29161 tagctggggg gatcgttggt ttagctacct tgattcaagg tatttccttt ggtccagcat
    29221 tatcagcagc attagatgtg aatgttcctt caaatgtcgc agatgcaatc aatagttctg
    29281 agattggtgc aacgattgca gatggcacac tgtcagttgg attatggggt tggctaaaac
    29341 tagatcattt gaatggaaac gcttatttta cagttatgat catgggagct atttcagtca
    29401 ttattttttg taaattgatg cttgccaaca ttacgatcaa aatgcctgat tcagtaccac
    29461 cagcagtatc taaagcattt gcagccattt taccagcgac gatcgcttta tacgtcattg
    29521 ctattatcaa ttatatcgta ggtcgtgtag ctgatgggca actgatcatt gatttggtgc
    29581 aaaaatatat tgcagaacca ttcctaggat tatctcaagg gttgggagca gtattgatcg
    29641 tcacagtatt tgttcaagta ttctggttct ttggtattca tggaccaaat gtattggcac
    29701 cagtgctaga gggaatctgg ggacaagcac aactaatcaa tattgatatt ttccaaaaag
    29761 gttataacgg aaaaactggt acaccagccg tgttagatgc aatcgaagat ggaaaagctt
    29821 atatgtgggt ccgcggatcg ttcgatgctt ttgcatggtt tggcggatca ggcggaacga
    29881 tcgtcttact gatagctatc ttgattttct ctaaacgtgc agattatcta acagtagcta
    29941 aattatccat tgggcctggt atcttcaata tcaacgaacc agtgatgttt ggtctgccaa
    30001 tcgtattgaa tgcaatcatg tttatcccat tcttgattgc tccagtagta gcaacagcaa
    30061 ttggatggac agctacttat cttggcctag tcgctccggt atcgcagcaa gtcacatggg
    30121 tagtaccgcc gttcttattg tcattcttag caacaggagc ggattggcgg gcaccgatcg
    30181 taacattagt atgtatggtc gtgactttct tgatttgggc accatttgtc atctctgcaa
    30241 acaaaatgga ccctgccgca ggcgaacaac aataagatga acgtgaggag cgggacgctt
    30301 taagtttcgt tcctcataat gaattttcga ggaggaactg aaatgattac aattgccagt
    30361 gcaatgcaac aagatgaaat caaagaattg ttagaaggat acaatgaaga aggaatgact
    30421 tttacattta aagaaaaaca aggaatcaag ctgttctttg aaacaagtgc agaagatccg
    30481 gaagttgcgg ctaaaaaagc aaaggaacta atcaaagcac agccttgggg aacagtcctt
    30541 tattttcaat caacagctgt ttagaaaatg gtttaaaaag ataggatggt tgagatgata
    30601 aaaaacggtt tatttttatg tagtattggt tctttgatcg tgttgtatag tttgaatcca
    30661 cattcgcaaa ggtatgattt gtatagtatg gtcacaggtc tttttctaac aggattagga
    30721 atctatttct tcatgaaggg gaaaaaaaga gaagaagcaa aggagaaaaa taactaatgg
    30781 aaatcacgaa aaaattaaat attccagcat cgttttttta cgataaagtt atggactctg
    30841 tccttttcga tgtacgtaaa gcgaccggca aatcagtaac tagaaaacag ctgaaaaatt
    30901 tggagtacgt caaacaattc tcgcaaaata accgggctcg cataaaaatc gaagaagtca
    30961 ttgaaaacca gtcttataag tttcgtacat cgacaacgaa gaatgaattc gtcgttcatt
    31021 atcaaatcaa accattggac gattcgacct gtgaggttca ttacacagaa aaaatggagt
    31081 cttatggcat gcttcaaaag ttgaatgata tgcttttagg aacaatcttg atgtatttta
    31141 aacggagacg tttcaaaaaa atgctagata tgatcgaagc aacgtattaa atcaatgaaa
    31201 catggtacta tttagttatt gaaaaatgaa gtaagctaga aggaattttt cataggaaga
    31261 tagatctttc ctgcgaatcc tcactagctt ttttgtagga aggggcagca aaatgacaaa
    31321 caaagtaaga gagctaggtg tatcttcgat tgaggaaatg tttgatttag ccacttatgc
    31381 atttaatggg gcagatacac ctgaaaggcg agaacgtttt cgtacacttg cggagaattc
    31441 ttggaattac ggattttttg atgaggagga tcggctaaca agtcaagtca tggcgacccc
    31501 ttttccagtg aatttttacg gacaagagta cctaatggcc ggcattggct atgttgcttc
    31561 ttatccagaa gcaaggggac aaggcgggat caatcagatc atggaaaaga tccttgaaga
    31621 ttgccgtgat cgtaaagtaa gcttatctta tctggcgcca ttctcctatc ccttctatcg
    31681 gcgctatggc tatgaacaat catttgataa aatcagttat caactaaaca gtcgtgatgt
    31741 gccgtttatc aaaaaaaaat ctggaaaaat aaagcgtatg gattttgaag atgcaaaagc
    31801 tgcaatcaga agaatttatg aacagatgcc ggaaaaccaa cgagctggtc tgaagcgcga
    31861 agactggtgg tatacgtata aattcaagca aaaaggcaat taccagtttg ctttgcattt
    31921 tgatgataat gaggaagcaa cgggatatat cgtttatcag cttgcaacgt cttcctttat
    31981 tattgcggag tggggatttt tggatcatga tgctttttgc agccttgttc gcttcgtaag
    32041 ttctcacaat ggtgcttttg aaacatttga atattcatgc ggctacggcg gtaatgatca
    32101 aaattatcta ttagaaaatc catttgcttc tgtaatgatc acaccttata tgatggcgag
    32161 gatcgtagat atttctttgt ttttggaaaa ttatccattt aaaaagagac aagctgcatt
    32221 tgccctacaa atagaagaag atcattatgc gaaatggaat gaaggaatcg tggaagtaac
    32281 aatcgaaaat ggaaaaaatc atctctcaaa agtagaacaa acaaaactcc caatcgttcg
    32341 aggaagtatc caacatatca cgcagctatt attagggtat cgtaaagtgg aagagttggt
    32401 attccaagaa agaatacagg tgacaaaaga atatgaagaa acgttaagct caatcttgcc
    32461 acagcaacag ccaattctta atgactattt ttgataaaaa acgggtgatg acaatatttt
    32521 tgtcaccacc cttttgtttt tcatttggca tttgaaggaa aatgttaaag taaatcctct
    32581 tttttcgtaa atttgaattt tttgttttct tttgttttag ggttttcttt tttgtggtct
    32641 tggattgctt ctttcgtaat cttttcccga ttttttttag atgaatctaa gcgttctgcg
    32701 tatacttttt cttttggctt atcattcatt ggaaaggacc tccctacatt atttcattct
    32761 acctctagtt tatcatctgt taaggactag tggaaacgtt ttgcctaact tataagctga
    32821 tttttttagc agataagctt gcaagtaaaa aacaaacaag ctacaattga tttattgaaa
    32881 ttgttcctgt agctcagtag gatagagcaa tcgcctccta agcgataggt cgctggttca
    32941 attccagtca ggaacgtata aataacccct gtatcctttg cggtacaggg gtttgttttg
    33001 tatttgtgcc aaaaatgtgc caaactagtt atcattttta tataaactat cgaacacagt
    33061 attgattttt tctttatcct gatcttcaag ctctcgaaca atatgaagat aagtagacat
    33121 tgtagtttct aaactgctat gtcctaaacg tttcgatacg ctaagtatat ttactccttg
    33181 ataaagtaaa atagatgcat gtgtatgcct tagtccatgc aaagtaaatt gcttttcaat
    33241 ccctaattct tttaattttt tgcgcaaata tttgctgacg gcgtttgatg aaactaatcc
    33301 attttttaag ttgaaaaaaa caaaattatg agggtttttg atttcaaaat tctcgaataa
    33361 ttctttttga ttgattttaa acttttttaa gagatcaatc gtatgtttat caatggaaat
    33421 tttcctattt gaagtttcgt tttttgtttt tccccattca tttaatttat aattccatgt
    33481 tttattaata gtgatgattt gatcttcgaa atcgatatct tcccatgtta atcctagaag
    33541 ttcagcaaat cgcattccag tggcaccagc aactaacacg agcataggag aagagtactg
    33601 cgcagaaagg ttttcttcta cgagtttcat taaagattta aattgatcat aatctaaata
    33661 tttatcttct tttggcttca atgaatcttt tcctttgatt actgcttttc tagttggatc
    33721 aaacggaatt aatccttctt ctacggcatc tttcaacgac gctctaatat ggttattaaa
    33781 cttaataacg gtagatttta catggtcttt agcatactta tttaaaaagc gttgatatcc
    33841 cactctatct aaatcagaaa tcaataccgc tggcatatat ttctttatgt tcattaacgt
    33901 atcttcgtat tttctataag tgataggaga tactgttcct tctttataaa gttgcatcca
    33961 atcctcaaag taatctgata ataatagatt tttgcgatcc cctttaaggc ctttgttcaa
    34021 gttatattct aattcgttgg cggcatcttt tgcttctcct tttgtcttaa atcctgattt
    34081 tcttatcttc gtgtattttc cgtcatcttt tttgtatgaa atttcgtatt gccaactatt
    34141 tccacgtttg actaatcttg ccataattga atcagctctc tttctctgat acaataggaa
    34201 ctataaagaa gcccattgtt tgggttttat tattttttgc acatcctttt tgcttgccgg
    34261 cgcaaggatg tgctatttgt cgttttaatg gtataattgg atgtgtatta gatcatccaa
    34321 tcagaggtgt ttattatgat taaagtgatt tttaaaagaa taactgaact tccagagttt
    34381 agattatttg ttgattattg gtatgtctgg ttttttattg ttgcattgct gataggtcta
    34441 gatgtcatat tagaaagaaa acttaagtaa gagttgagtt aataaattga attcctaaat
    34501 gagatatttt gtagcccata ttttgtttgc cgacatcacc taatactatg gagctaatcg
    34561 ttttttctaa cagaccaaaa tcagataatc tatttaagct accatctatt agctcttgtg
    34621 aatagccaga catgctgata tttccagtga aattttcgtt tccacgactc attaagcatg
    34681 ctaacaattg aatctcaatc gatgttaatt gattcagtac aagaagataa tactcctcgt
    34741 tatcccatga agcgttgtta attcgaagta aacaattctt ataaagattt ttatacatat
    34801 ctattttatt ttgtgccttt gatttttcta cctcgtcatt tatcccttcg aatattccaa
    34861 tgagttggtc cttgttctct aagttgaaaa catcttctgg aatttgatcg cgaatgtttt
    34921 ctaatgattc gtttaaattt ttgtagaatt tctcgatgcg tttgaaacgc ttctcgtttt
    34981 tagacccaaa ataaagtgac tgcacaacgc caccaatata aggaattgct ccaataccgc
    35041 cttcaactat taattcaaga tattcttttt tggttagttt ttcattgcta ttatccatag
    35101 ttacctccta ttttgtcatt tcctttacaa gcattgtgac tcctgatggc actcttttgt
    35161 ataggtttta ttattgtgca caatctaact cttagtgggg cgtggttcat ttatttttta
    35221 cttactttac tattaatcat atcccattga gcataggatt tttctatgtt cgatcctctt
    35281 gaactaattt ctcctgtaaa agttacttta tcgccctttg taaaggtatc agcattgttt
    35341 aagtccttcg caaaaattac atatgaaact ttaggtgttg cagaaatatc attccaactt
    35401 ttatcatcgt actctttgtc tgctataatg gctattctag tagtcattga ttcgataaca
    35461 gttccttcaa aagtatatgt tttaccacta atatatttag taaaagctgt attttgctca
    35521 gtagctggag taatagaata ataactatct aagaaagcac cccagtcatg attatttgtc
    35581 tctaaaaatt cttcaaattg agttaggctt ttattgctgc tgttagatgt agtagtttga
    35641 gtatcagatg atgagctttc ctgtttgtta ttgtcatttg cctcgtttga tgaggaaagc
    35701 gagaaaccta cggtagtaaa aataatcccg ataataagga gaatcatagg tgttttctta
    35761 tttgtttttt tgataaatct tacaattaac atgattaaac ctataataaa taaaacaata
    35821 ccagtaaaac caaatatacc gtccattaat agatcctctt tctcttttga tattgaatat
    35881 tataaaccaa gcaattcttt tttcttaaaa tcgaattctt cttgattaat aatcccttca
    35941 tctaacaact ctttatactt tttaatttca tctgcacttg aaatttgtgt ttctttggaa
    36001 ttattatcta atatagattg ttgcttctct atatattttt ttaaattttc catttcattc
    36061 caatattttt ttgtaaacat aacggtgttt tcatctttcg tggccgctaa tatacctccg
    36121 cgactttcgt ttccgcctag caaggtaaat tgtatataac cattactcat acctggtttt
    36181 tttaattgta cggctgatat atttttaaag ggg
//
LOCUS       DACDAF010000019        34780 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.019, whole genome shotgun sequence.
ACCESSION   DACDAF010000019 DACDAF010000000
VERSION     DACDAF010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 34780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.019"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(433..2325)
                     /locus_tag="IVZ69_000883"
     CDS             complement(433..2325)
                     /locus_tag="IVZ69_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182990.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            complement(2322..4049)
                     /locus_tag="IVZ69_000884"
     CDS             complement(2322..4049)
                     /locus_tag="IVZ69_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8182991.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            complement(4065..4715)
                     /locus_tag="IVZ69_000885"
     CDS             complement(4065..4715)
                     /locus_tag="IVZ69_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP8182992.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            4919..5215
                     /locus_tag="IVZ69_000886"
     CDS             4919..5215
                     /locus_tag="IVZ69_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP8182993.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            5407..6027
                     /locus_tag="IVZ69_000887"
     CDS             5407..6027
                     /locus_tag="IVZ69_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HAP8182994.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(6119..7285)
                     /locus_tag="IVZ69_000888"
     CDS             complement(6119..7285)
                     /locus_tag="IVZ69_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP8182995.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(7297..7650)
                     /locus_tag="IVZ69_000889"
     CDS             complement(7297..7650)
                     /locus_tag="IVZ69_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP8182996.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            7778..8800
                     /locus_tag="IVZ69_000890"
     CDS             7778..8800
                     /locus_tag="IVZ69_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HAP8182997.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            complement(9239..9673)
                     /locus_tag="IVZ69_000891"
     CDS             complement(9239..9673)
                     /locus_tag="IVZ69_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8182998.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKK"
     gene            complement(9783..11642)
                     /locus_tag="IVZ69_000892"
     CDS             complement(9783..11642)
                     /locus_tag="IVZ69_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP8182999.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(11760..12919)
                     /locus_tag="IVZ69_000893"
                     /pseudo
     CDS             complement(11760..12919)
                     /locus_tag="IVZ69_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(13226..14650)
                     /gene="araA"
                     /locus_tag="IVZ69_000894"
     CDS             complement(13226..14650)
                     /gene="araA"
                     /locus_tag="IVZ69_000894"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HAP8183000.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(14666..15364)
                     /locus_tag="IVZ69_000895"
     CDS             complement(14666..15364)
                     /locus_tag="IVZ69_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP8183001.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(15321..16982)
                     /locus_tag="IVZ69_000896"
     CDS             complement(15321..16982)
                     /locus_tag="IVZ69_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HAP8183002.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            17200..18600
                     /locus_tag="IVZ69_000897"
     CDS             17200..18600
                     /locus_tag="IVZ69_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HAP8183003.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(18852..19931)
                     /locus_tag="IVZ69_000898"
     CDS             complement(18852..19931)
                     /locus_tag="IVZ69_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8183004.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(20017..20976)
                     /locus_tag="IVZ69_000899"
     CDS             complement(20017..20976)
                     /locus_tag="IVZ69_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HAP8183005.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDTLIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(20988..22511)
                     /locus_tag="IVZ69_000900"
     CDS             complement(20988..22511)
                     /locus_tag="IVZ69_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP8183006.1"
                     /translation="MDEEVKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHE
                     TADGDGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIE
                     PNSFGLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQ
                     KKPFGVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPR
                     LPSYPEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFD
                     RQIEEIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMED
                     TLLFGSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAK
                     GQVLKQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLL
                     DQGEHYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(22521..23084)
                     /locus_tag="IVZ69_000901"
     CDS             complement(22521..23084)
                     /locus_tag="IVZ69_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HAP8183007.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(23090..23953)
                     /locus_tag="IVZ69_000902"
     CDS             complement(23090..23953)
                     /locus_tag="IVZ69_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8183008.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(23967..24863)
                     /locus_tag="IVZ69_000903"
     CDS             complement(23967..24863)
                     /locus_tag="IVZ69_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8183009.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(25038..26309)
                     /locus_tag="IVZ69_000904"
     CDS             complement(25038..26309)
                     /locus_tag="IVZ69_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP8183010.1"
                     /translation="MKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTLTFWNGF
                     TASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFIALNYPD
                     FAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMYMYWNND
                     LFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLANGGKLV
                     NDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIEINGPWL
                     NNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFLKYWNTT
                     EIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQISAINNDI
                     INPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(26299..27816)
                     /locus_tag="IVZ69_000905"
     CDS             complement(26299..27816)
                     /locus_tag="IVZ69_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HAP8183011.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            28014..28904
                     /locus_tag="IVZ69_000906"
     CDS             28014..28904
                     /locus_tag="IVZ69_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HAP8183012.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(28977..29801)
                     /gene="nadE"
                     /locus_tag="IVZ69_000907"
     CDS             complement(28977..29801)
                     /gene="nadE"
                     /locus_tag="IVZ69_000907"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HAP8183013.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(29813..31285)
                     /locus_tag="IVZ69_000908"
     CDS             complement(29813..31285)
                     /locus_tag="IVZ69_000908"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HAP8183014.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(31922..32284)
                     /locus_tag="IVZ69_000909"
     CDS             complement(31922..32284)
                     /locus_tag="IVZ69_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP8183015.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            32507..33259
                     /locus_tag="IVZ69_000910"
     CDS             32507..33259
                     /locus_tag="IVZ69_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP8183016.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(33399..34322)
                     /locus_tag="IVZ69_000911"
     CDS             complement(33399..34322)
                     /locus_tag="IVZ69_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP8183017.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(34337..34609)
                     /locus_tag="IVZ69_000912"
     CDS             complement(34337..34609)
                     /locus_tag="IVZ69_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183018.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        10267 a         7228 c         6005 g        11280 t
ORIGIN      
        1 agaggttgtg aaaaagtcgc ttagtttcga gtagtaagaa aaattttgtg aaaatggctt
       61 tctacatttt tgcataaatt tggcttaata ccgagaaact ggcttttgaa caccgtttac
      121 caagaggttg tgagcctgcc gtttaactcc gagtcacaag gagcaatttc aaaaaacagc
      181 ttctcaggtt tgttgactat tgtgacttgt gaccgaggag ttggcaggag aacaccgttt
      241 aaggaagagg ttgtaaaatc agcggtttga cctgagtatt agagatacaa aacggaaaaa
      301 tagcttctca tattttgccg ttttttgagc taataccgaa ggacagctga ttgaacaccg
      361 tttattcgga aaaagggact gtgacacgac ttttgtcaca gcccctaaaa aaaataataa
      421 atttgtacta ttctatgaag cttcttcttc agaaaactga ctgttataaa gatctgcata
      481 gaatccgtct ttttccatca atgtatcgtg gtttcctgtt tctacgatcg aaccatgatt
      541 catcacaata atgttgtctg catcgcgtat tgtagacaag cggtgagcaa caacgaaact
      601 tgtccggttt tccaataggc ggttcatcgc tttttgaatc agtatttctg ttcgtgtatc
      661 tacactagat gttgcttcat caaggatcag gacatctgga tttgctaaga atgcccgcgc
      721 aattgtgatt agctgacgct gcccttgcga aatattgctt gcatcctcgt ttaatacagt
      781 gttatatcct tctggcaatt tacgaacaaa atcgtctacg tgagcagctt tagcagcctc
      841 aatgatttgt tcgtctgttg catcgtcgtt cccatatttg atattgtcat agatacttcc
      901 tgtaaacagc caagtatctt gcagtaccat tgaaaactgt gcgcgcaatt catcacgtga
      961 aagatcacgg gtatctacac catcgtaacg aatactacct ccagaaacat cgtagaaccg
     1021 ttcaagaagg ttgatcagtg tcgtcttccc tgcaccagtc ggacctacaa tagcgaccat
     1081 ctcaccaggt ttgacatcca agttaaaatc agtcattagc aagttatctg gtgtgtagcc
     1141 gaattgaaca ttttcaaaac gaactttgta tggtgtatct ttttcttctg gaaggccaga
     1201 tttttcattg gacatctctt cttcatccaa cacttcaaat acccgttcgg ctgaagcaac
     1261 tgttgattgg atagtgttca tcaaacttgc aagttgagtg attggttgag agaactgtgt
     1321 tgtatattgc aagaacgctt gaacatcccc taatgtcatg ttcccatttg caacttttac
     1381 tccgcctagt acagcgacga acacatagcc tagattttta acgaaattca tcaacggcat
     1441 gatgattgcc gaaataaatt gagctttcca accagcggca tacagattct gattttcttt
     1501 ttcaaatact tcctggtctt tttcagtatg attgaatgtt ttaacaatgg tatgaccacc
     1561 atatgtttct tctacttggt tattcaataa acctaaactt ttttgctgat ctgcgaaaaa
     1621 cacttgtgat ttcggcgcta cgatcatcac gatgatcaag cttaaaggga tcatcaataa
     1681 cgcgactaac gtcaattgcc agctgattga aagcatcatc acgatgaccc caatcaatgt
     1741 gactgcacta gttacaaatt gagtcaaatt ttgctgcagc gtgcttgcga tgttatccat
     1801 atcattgatt gctcgagaca tgatatcccc atttgtatgt gtatcataat aggaaatcgg
     1861 tacacgattc attttggctt ccaaatcatg acgtaattca taaactgttc gttgggaaac
     1921 acgtgtcata ataaattgct gtaaaaagtt gaatacagca gaaatcaaat acatcacgat
     1981 tactgtcgca atgatctgcg cgattttatc aaagtctatc ggaaattttg ttacttgttg
     2041 gccttgttgc atctgttgag cgccagccat tacacctttg aatatttctg tggttgcttt
     2101 ccccaagacc tttggtgttt ggatttggaa gatcacggct gctattgcta gtacaaatac
     2161 agcgatgatc gcaaccatac gtttagacat atagccaaac aatcggcgta ccgttcccca
     2221 gaaattttta ggcttttcac cttttacacc gagatttctg ccaggtccac catgtcctgg
     2281 accgcctgct ggtccatgag agggacgtgt gtttgtttta ctcatgctaa gtcctcctct
     2341 cttagttgtg aatgaacgat ttcttgataa gtttcgtttg ttgctaatag ttcttcatgt
     2401 gttcctttgc caaccagttt tccttcatct agcacaagga tcatatctgc atccattact
     2461 gtacttactc gttgagcaac taaaacggtg atactttctt tcatattcgt tttcaatgct
     2521 tggcgaagat tggcatccgt tttgaaatcc aacgctgaga aggaatcatc aaacacatag
     2581 atatctgctg ttttgactaa tgcccgtgca attgccagac gctgtctttg tccaccagag
     2641 aagtttcctc ctccttgttc cacatggcta tctaagccat cttccatctc tgaaacaaaa
     2701 tctttagctt gtgcgatttc taatgctttc caaatcattt catctgttgc atccggctta
     2761 ccatactgca tattgtctcg gatcgttcca gagaacagaa ctgctttttg aggaacaaag
     2821 cccattaatt ctcgcaaatt atattgagtc atgtcactaa tgtccgttcc atttatttgg
     2881 atcgaaccag attcgatgtc atataatcga gggatcaaat tgactaaggt cgttttacct
     2941 gaaccagtcc cccctatgat tgcgacgatc tcgcccgact tggcttggaa atcaatatct
     3001 tccaatgcaa gtttttctgc tccatgatat cgataattga catgattgaa ggccaatgtt
     3061 gcgttttttc cagcaaaaga aactgtttta ggattttcag ggtcatggat accgattttt
     3121 tcatccaaca cttcattaat acggtcagct gaagcttgtg cacgaggcac catgataaaa
     3181 atagcggaaa gcatcataaa gctgatcaag atctgcatcg cataagtcat aaatgcaatc
     3241 agattaccga cttccaaagt catatctgct atgtagtgtc caccaaacca agtgattgct
     3301 acgtttgtac cgctcatgat caatgtcatc attggcatca tcaatgcgac gatcgtatta
     3361 actttgattg ccgtatttgt ataatcttta ttcgctaaat caaaacgatt ttcttcaaag
     3421 cgtgtcttat cgaatgctcg aatcactctg acccctgtca atccttctcg aaataccagg
     3481 tttaaacggt cagttttctt ttgcatactt ttgaataatg gaacagcaaa gtacatgatt
     3541 ccgccgatca aaataatcat tactgggatg acaactaaga agatttttgt caactgatga
     3601 tctttttgat aagcaagtat gctcgcgcca atcaacgtga ttggtgcatt gatcatcata
     3661 cgtaaaaaca tttgtgtaac catttggatt tgagtcacat cattggtcgt tcttgtgatc
     3721 aaagaggccg ttccatattt atcaaacgca tcttttgtca gactctctga ttttttatag
     3781 acatccgtac gcaattgctt acccagtttc tgtgattcac gagtagcaaa aaatgtattt
     3841 gcgatagcag ctaagatact gatcaaagaa aagccgatca tcacaaaacc tgtatgccaa
     3901 atataatcga catctccttg cgctacccct ttatcaataa tattggaggt aagtgtcggc
     3961 aaatataaat ctgccagtac ttggatcacc atgaaaactg cagctgcaat tgctgaagtc
     4021 aaggagatcc gttttacgat ttttagcatc tagttccctt ctttctattt atatactccg
     4081 tttttcagcc aagaaagttt caaattgaat tcactgattg cttgctctac tgagtaatct
     4141 tcagatgttg aaaataagcg atacgaatgc gcaattgttg taaatacagt attcatcact
     4201 aattggatca gtaattccaa ttcatgatca ttttttactt tcagcttcgt ccgatcgatc
     4261 aattcaagca actcttttgc atcttgtttg tgttctttat gtggatcgtg aggcgttttt
     4321 tggcgactcg tatgaggagc gacttttctt gaggcacggt aatccatgtt cataaacaag
     4381 ttacgataaa aagaagcatt ctcgccttcc aaaatctcat aaatcatttt agaaaaatag
     4441 gattcgaatc ctttgaatag atcaccatcg gattctttca ttagttgtaa catatcttta
     4501 gagctgtcac gtctcattgt ctcaaagtaa taaaaataaa gatcctcttt atcttcaaaa
     4561 tactgataga aactgcctct agggatatcc gctaatttga cgatattagc aatcgaagct
     4621 tcttttaagg gtactctaga aaactcgatt ctcgcagcct cgattagtct tttttgtttt
     4681 tctttaggca aatggaaaaa tgtctgtgtc ggcatatgga ttctcctttc tttcaagatg
     4741 acacattgtc atatgacgct atgtcattat aacacctcct acctgttttg caagacattt
     4801 gcatagtttt tttcattatc atccgataca ttaaaaaagt gataagagga atccttccat
     4861 ttgaattaat gagagttgcc cattaaaata gccacatact aaacaaagga tgagataaat
     4921 ggcccaatca attagtgtcc aagacttcaa taaattgcct ctcgatgctg acagcatcgt
     4981 tttagataca agaaatacct tagattacac aaaaaaccac ttaagccact cgctttctat
     5041 ccccgctgct atcttgccaa gacaattaaa aaatctagat ccaaagaaac tttattatat
     5101 tctaagctat acaggcaggc gatcagaagc attagccgat caacttactg ctaatggttt
     5161 tcgtgctgtt tatatcattg gtgggatgga agctcttcag tcgagtgttg cttgaatatt
     5221 gcttgttaga ttcaaaagag gctgtgacaa aaaatcgtgt cacagcctct tttataccct
     5281 gtcttttttt agttatttat tcttcaacct tatcaatatg acttgatagc cttttctttt
     5341 tcgagtaaac tgattttgtt agtcatagtt ataacaatca tagcaataaa aggagaaggt
     5401 aagcatatgg catctgtttt agtagtcaaa ggtcatcccc taactgcaga agaatcgcgc
     5461 acagttaagg cattgacgtc ttttttaaca agttataaag aaaatcatcc agatgatgaa
     5521 gtgactgttt tggaacttta tcgcgatgat attccggaaa tcgatgaaga attattatca
     5581 ggttgggaag cattacgtgc tggtgcagaa ttcacttcct tatcagaaag tcaacaacaa
     5641 aaaattgctc gtttcaatga attgactgat cagttccttg ctgctgataa aatcgttatc
     5701 gcaaacgcct tatggaatct aaatatccca acaaaattaa aagcttggtt cgataccgtc
     5761 aatgtagctg gaaaaacgtt ccgctataca gaaaacgggc cagaaggatt agtgacaggt
     5821 aaaaaagcac tgcacatcca atctaatggc ggtgtataca acggacaaga ctttgcctct
     5881 caatatgtaa aaggtatttt aaactttgta ggcatcgatc aagtagatca gctattcatc
     5941 gaaggaatcg attatgaccc tgaccgtgca gatgagttga tgcaaaatgc attagataaa
     6001 gctgctgctt taggtaaatc attttaaaaa ttgagataaa tgcatacaaa agagacagag
     6061 gaaaaaatct tcaaagcagc atttgtgcct tggatatttt cccatctgtc tctttttgtt
     6121 attctttctg ctttttcaac ggattttctt cataaagaga agagattgtt gtgtaccatt
     6181 caaaaacatg agtaatcact actttagctg ctgcataaac aggaatcccc aagatcacac
     6241 cgatgattcc gaacaatttc ccagaagtca gcagaactaa taaaatcgtt actggatgga
     6301 ttgctaactg attccctagt actaatggag agatcaagcg tccttctatt gtctgctcta
     6361 ctgcaaaaac gatcagtact ttgatgatca tgaatggacc tgctacaatg gctaaaaaga
     6421 tagccggaat catcgctaaa aatgatccta agtaagggat caggtttaaa aaacccgcaa
     6481 taatccccaa cgtgacagca tactctaaac caatgaccgc aaaaccaatc ataaacatga
     6541 ttgccacagc aaaagccaca gttagttgtc ctcttatata agaagaaact tgactattca
     6601 tttcactcag cacattcaac gtcggttttt gcatgcgtgt cggtaaaaat ttgacaaaat
     6661 aaggtgctaa ttgtttaccg tctttcaata gataaaataa gataaacggc atcgtcagca
     6721 gagccactaa aatagtcgct accgcgccga caaaacttcc aagactctga actgtactct
     6781 tagatatatc ttggatcata tcgcctgccg aattcatgaa cttatcacct gctgtttcca
     6841 actgttcgcg aaattggttg aacagcgggt cccgcaaaat ctcggttaat ttattatcaa
     6901 tcgtatctac atattgaggg aagttactga tgaagctcac tgtttgttcc tgaatcttag
     6961 ggatgatcac tacgctcccc catgcgatta gtgcaacaac caaaacaaac agcccaatga
     7021 tactgtaaag ccttggtact tttcgctttt caaagtaatc aactaccgga ttcatcaagt
     7081 aatacaagat tcctgctaaa atgataggca gacctacgat tgctaaaaat tgccagattg
     7141 gtgcaaacaa atatgaaact tttgtaaata aaaagacgat cagcaatatt aacaatacaa
     7201 caagtaaggc tgtgactact tgattattta aaaaccagcg ccaaaaccac gataccggtc
     7261 tgttcttctt attttttcct tccataattc ctcctgttag ttataaaaaa tttggcttcc
     7321 caaaccaata gcaggcagtc tatgcggatg aagatagatt ccatttgcaa tttgtccttc
     7381 ttctggacaa gcatcaaaaa tcaatgatac gtgagctact gtctttaaat tcccattggc
     7441 catcggaccg acataatcga tcgtatatac ctgatcatca aaagcaattg ttccgcctgc
     7501 tttcaaagaa aaaggttcgt cttttgatac ttcttgaatc accgaatatt ttcgtaaggc
     7561 agctgttgct gttttatcga acaaaatcag catgggttct tccttgttta ttgcttctgt
     7621 cccaatttct gtaatctttg cctgaatcat tgcactctct cctttaattg ctttcaaaaa
     7681 cagtataaca cattctcatt ctttagccgt gtggaataat tatgtgatag aataaaaacg
     7741 aaaactattt cattacaatt aggaggaatc agctcatatg atcgaaaaga taattttagg
     7801 aacctatacg cgtcgcgaaa gtaaaggaat ctatacgatc gaccttgata cagaaaaaga
     7861 agaattagcc aacctttcat tagctgttga agaaaatagc cctacctatg tagcaaaaag
     7921 taaagctggc aatctttaca cagttactag tgtggatgga ttaggtggtg ccggtgcgta
     7981 cgataaggat tttcattttt tgaatgcggt aacagagtct ggcgctcctt tgtgttatgt
     8041 agcggttgat gaagcacgtc aattactata cggggcgaac tatcataaag gtgaagtaaa
     8101 tgtctaccat atattaggag atggcgaact gaaagcagca gattcaatat tccatcaaga
     8161 agcgacaggt cctcataaaa accaagatca tgcgcatgtc cactatacgg atctgactcc
     8221 tgaccaacga ttagtcgtat gtgatcttgg tacagatcgt gtgtatactt atgatgtgtc
     8281 cgaaaacggc aaattgaatc ttgtaactac cttcactgca gagccaggaa caggccctcg
     8341 ccatcttgtc tttcatccaa atggacaatt cgcttattta tttggtgaat tagacagcac
     8401 agtccgcgtg ctttcttata ataaagaaac aggtgctttt gaagaattac agaaaatatc
     8461 gaccttgcca gaagaattcg acggtgaaaa tggaggggca gctatccgca tttcaaatga
     8521 tggcaagttc ctttatgctt ctaaccgagg acataactcg attgctgtat tcgcagtttt
     8581 tgaagatggt tcccacattc aaaacaagca aatcatctca acagaagggg attttccccg
     8641 cgatttcgca ctagatccaa gcaataattt tgtcgtgtgt gccaatcaga acaccgataa
     8701 tctgacatta tatcgccgtc atcctgaaac aggattactg gaattactga aaaaagatgt
     8761 ctatgtacca gaatgtgtct gtgtttattt tgatcgttag taagaaaagg agaatgaaat
     8821 gaatcagcaa gacgtattag acagactacg ggaagaacta aatattcctt tctttgatgg
     8881 gaaaatcgaa gataaagagt atagcgaaga ggaatatcag aaactcaaag ccgatttaca
     8941 gaactacttt gaacaatatg tacagaatgt agaaaactaa tcagctttcc atactatctg
     9001 aaaagaacat caggacaaga cttttccgtc tatcctgatg ttcttttcta caaataaaaa
     9061 accgccgaga tggttagact cgacggaaaa ggagtattta ctcgattttg agtaagtaca
     9121 aggttgttgt tggttatagg tatgtcatta tcataaagga ttttgatcac tctatcataa
     9181 aggtaatatt acatttatat tagataactc tagtttttat tgttatcaaa gatttctttt
     9241 attttttcaa caacaaatta gtcatttttt ggatggcagc tgtcaattgg tctgtcgctt
     9301 ggtcttgttt tgcttcagat gtattgaata gatcttcatc tacccctgat tcaagatcga
     9361 tactttggat catttcttca cagcctgcta catatgaaag ataagctttt tcaaaatttt
     9421 tatgaatgcc cattgctttt gctggtggac gcaaagtact gactttcata agcattgccc
     9481 gatatttttt tgttccttct tcaaataaca ggatgatctc ttcaagagtc gatttgtcca
     9541 gttcacttgt ttttccttca tcaattgcgt ttctgatcac ttcatatttc ggatgcattc
     9601 cttctccgat tgcttctgtt tccttgacga tttgatcgat ggactgcaca taatagccaa
     9661 tattcggtaa catgttcgtt ttcctacttt ctccattgtt gttattattt attctacttg
     9721 tttttatcct caaatgacaa gtacttgaaa aaatttaatg gtttctatac agctcgccat
     9781 tcttattcgt gctcaaagaa accatctgct aaactatatt gtttccctgc gacaatgtca
     9841 tattggatca attgatattc gtcgtaaatc tcttgttgcg agcgattgaa ttgcgcttct
     9901 ttataccact gtccgttttg atagtacagt tctcgttcaa acgccggaag ttcctgttct
     9961 aatgataaaa gcagctgata aaagccattt gttgtctgat tcgtctgttc cattagattc
    10021 gctgcaaaat aaaacggact ggtgattgca tcgtgagtcg tttgcttttc taattctcct
    10081 ttactgtcga acataagaaa ttgtgtttca tgcaatgttt gtttgtcatt ttttgcttgg
    10141 atcgtatctg aatagatccc tggaagatga tccccccaaa aaacaactaa agtccttcta
    10201 gaaagattct tcaattcttc cgtgaactgc ttcagtgccg tgctgctata ggaaatatct
    10261 tgcagataat tctctaagtc aagtgtccca cttccatctg aagtttttgc aggatagtct
    10321 agattatcat actttccatc gtagggcata tgtgtctgca tcgtgactaa atgaatgaac
    10381 tgaggtgttt tttcttcctt gagaagtgtc attacttctt tgtaagctga ctcatcagaa
    10441 atatatggat tattctctat cgtatccgta taggtcatcg tacgctcgct gatgaactgg
    10501 tcaaatccta atgtctgata aacatcctct cttttataca tcgaagtatt gtatggatgg
    10561 atcgctgtcg tctggtatga ttgtgcgttt aacgctgaaa cgatagaagg aagctgatcc
    10621 atttttggta caagcatcgt gtaaggggtg gtgagttgcg cattaaataa cgccatagaa
    10681 aaaccagtca atgcttcaaa ttcgatattt gctgttccac cgccatagtt ttgagaaagc
    10741 atattgccac tatatgtttg atcagctact tcataataat ctgccaatgg ctcaccagat
    10801 acttctacgc cgtttaatcg actaggatct gagaaacttt cactcatcac gaacacgatg
    10861 ttcggcgact cttcctctac agttttattt ttttcatcgg ctagcttctg gtatttttca
    10921 gtgatttctt tgatcttttc tttcgaatat ccttcaggtt catccattgg ttctaccttc
    10981 agattgtaca aaaacccacc gataaaacca gtgttatagt agttcatttt ctggctgtaa
    11041 ggtatccata gtgccgtttt attatatgct tttcgcaaca aattatcggg attgttgaaa
    11101 ttactgatat accctagcag tccaattgcc acaagcagtg tcgttaatcg gatcaattgg
    11161 aatcgccttc cttttttcag gcttcgaaac atgtaccagc aaaacaatcc tatcacggtt
    11221 cctgcggcag ctaagatcac tgtaaacagc atagtgccgg tcatatcttt cagcaatccg
    11281 atttcagtga tcatcttcaa atcgtctgga taaatcggtt cttgccgata actcattttc
    11341 atataatttg caaaacctaa tacaccgatg gctacgacat acgtaaggga acctaaaggg
    11401 acagatcctg ctagtgcaat cagaaaaata agaataatca gcaagacgag acaggctaag
    11461 aagaattttt ccgtatgcca agaaaaagca aatttcaacg caaggtctac ggatagatca
    11521 ttttgacacc actgcaaaaa taaattacta aaaacaacaa gaaaaaagat actgatgatt
    11581 gctgctgttc cttttaaaat ctttttctgt ttggtcgaaa gtctgcttat atatcttttc
    11641 aaatgcttgc tccttcattt ctatcaataa aagaatgttg cttctcttat tttagttgta
    11701 cgaaattcga aagtaaagaa cggaaagaag aattaatgaa atccaaatat tctctttctt
    11761 tatggccttt ctggtttctt taataagcgg acctttcgta ctccagaaat tttttctagc
    11821 tgttgtttca cttgattgag ctgttcaaaa tcagtactgt ctatgtcaat caatatgtag
    11881 acatgctcat tcttatggtt acgcgatata tctgcgatcg ctagctcgtt ctcattcagc
    11941 agagaaaata tctctgctaa tatattggtt ttcttttgat aaaatatagt gaatcgaaac
    12001 ggcgcttgga aaaacattcg tgcggatgga taattgaccg cttctctaac cgtaccgaac
    12061 aaaagataat cttttaaggc ttcaactgcc aaacgtccgc tgtctgccaa agcttcctga
    12121 gtcgatcccc tagatgaggc aacataagta tacggtcatt ttctaagaac tcttcttctg
    12181 gaaaatcagt caagtattta gccagatgtt gtttttccaa tgcttgcata acagcatatt
    12241 tatcaacaat ttcacttctt cctacattga taagtacagc atcttttttc attttttcta
    12301 tattcgcctg atcgatcaat ccttttgtat cttctgtcaa cggcagcatg actacgatgt
    12361 aatccgaggt agaaagaact gtttctaaat ctgcttgccg aacataatcc aactgggcat
    12421 cgcggataga ataacccaag acatccatcc ctaagctata gcaacttagc gctacttttg
    12481 tgcctatcgc tccaagacca agaagaccga tggttttgcc ttgcaattct cgtcccacat
    12541 aagcacttct tttgttttct gcctgttcta aaatattagg acctgttagt gtttgtacca
    12601 tacgacttgc ttcgattatc ggacgggaag ataagagcaa acagcacaaa acaagctctt
    12661 ttactgcatt agcatttaca cctggtgtat tcatgacgat cgtcccgttt tcagaagctt
    12721 tttcaacgtt gatcgtgttc accccaacac cagctcttga aattgctagc aaatctggtg
    12781 taagccattc atctttcact ttcgtactac gaataactat tccttcggct ggcaaatcat
    12841 ctattatttt gaaatattcc ccttgtaact tttctatctc ttgttctgga atagcatcaa
    12901 tcaaatgaac gtgatacata aaaccccctc cttactaaca agtatctcga aatttctgca
    12961 attagacaac tgtttaccat ttgacttcct agaagcaaaa agagcagtta gagcagagta
    13021 ggctgagtga taaaaataag gctatgacaa gttactgcca taagccttat tttcgagagc
    13081 aaaatattga gggtgagata tcttgataaa tggtgttccg ttagctgaca ttgataataa
    13141 gactaaattt caaaaaagtt gaaaagcaaa tttcgtcaat ctcttcttat ttcttaaaac
    13201 taagtggctt tttcacaacc tctttttatc taataaccac tgtttccaac tcaactaatt
    13261 ttgcccacgt ttcaatttga tctgttgtta gatttagcga gacaacggta tgatgaccgc
    13321 cacctgcctg aatccatgaa tggacacctt catggaaatt cggtttagtt ttccataaca
    13381 cacgtgcaac aggtaaatta ggtgcttcag tcgttggttc aaaggcttct acttcattga
    13441 tcagcagttt ataatgcgta ccgaaatctg ccatcgatac gactacccct tctcctgctt
    13501 tcccatcaaa tacaagacgc gccggatctt ctctatctcc cattgataaa ggagaaacaa
    13561 cgattcttgg tttcgtcgca gcaagcgtcg gatctacttc catcatatgg gattccaaga
    13621 ttgcttcttg gccactagct agctcgtaag tataatcttc catgaatcct gtatctttcc
    13681 ctcgagccat gattttcagc aaccgatcaa tcgctgcagt tttccagtcg ccttccccag
    13741 caaaaccgta tccttctgcc atcaaacgtt gtacagctag tccaggtagt tgtttcattc
    13801 catacaggtc ttcaaaatta gtcgtaaaag cgttatagcc tccttcttct aagaaacggc
    13861 gaataccgat ttcctgctga gcttgtactt ttacatgttc ctcccatgtc ttttcttcat
    13921 aatcaccata gtcgaaggta tacaattcct tgtactcttc aaataattga tcgacttctt
    13981 cgtctgatac gcgatcgatt acttgtacaa gatctccgat accaaaataa tcaacagtcc
    14041 aaccaaattg aatctgtgct tccactttgt ctccttctgt gacacccacg tttctcatgt
    14101 tgtcaccaaa acgagccact tttattccaa aactttcatt ataggctact gcaacatcca
    14161 tccaatcagc aatctctttt tggatctcag gtcgtttcca gtagccaacg acgattttat
    14221 tttgtttatt taatcgagca ttgatgaacc catattcgcg gtcaccatga gcggattgat
    14281 ttaaattcat gaaatccata tcgatcgttt tccaaggaat gctttcgtta tattgcgtag
    14341 ctaaatgaag caatggtttt tgtagaagct ttgtcccgcg gatccacatt tttgctggtg
    14401 agaaagtatg catccaagtg atcacacctg ctacttcttc tcgataattg acctctttca
    14461 tgatttttgt gatcgtatca gcagtaactg ctaattcttg aaggcggatt ggataaggca
    14521 attggccatt ttcattcagt tcatcgacca tttcttgtgc atgtttcttt acttctcgca
    14581 gtgcttcttc cccatataaa tgctgtgatc ctacaacaaa ccaaaattct ttttctccaa
    14641 tattcaacat aattagccac tccttttatt tgttttgtcc gtaatacgca ttttttccgt
    14701 gttttcgtaa ataatgttta tctaaaatcc gttgaggcag ctcttctgaa aatgaattga
    14761 gctgtctggt aaataaattc atcttgcata cttcatctag tacgactgcg ttcattaccg
    14821 cactttgcgc atctttcccc caagtaaatg gaccgtgtcc gtgtaaaagt acccctggaa
    14881 ttgctaaggg atcaattttg cgttctttga atgtttctat gataactttt cctgtttcat
    14941 attcgtaccc gctgtcgatt tcctgttgtg tcaaaaatcg agcacaaggt accgatccat
    15001 aaaaagtatc tgcatgcgtc gtccccatcg caggaacatc caatcctgct tgtgcccaga
    15061 tcgtcgccca tgtcgagtga gtatggacga ttcctccgat ttgaggaaat gaacgatata
    15121 aaacagcatg agtaggcgta tccgaagagg gattgagttt accttcaatg atatgattgt
    15181 ccaagtccac aacgaccatg tcgtctgctg tcatctcttc ataactgact ccgctaggtt
    15241 tgataacgaa atatcgtgtt tcaggatcaa aagcgctcac atttccccat gtatatttga
    15301 cgagtccgtg tttaggcaag tcaagatttg cttggtatac ttcttctttc agttgttcca
    15361 gcattttcta tcactccttt ttcttgcaat tgatgaatcg ctgttttttc aatgtcgatc
    15421 ccctcacggt aacgtctcat aaatatctga tagcctgcta tttcttctgc tgaaggtgtg
    15481 atggtgattc cttggtcttg tccaaacacg tcttctgcca agaagttttc taaagacttc
    15541 ccatgtcgat ccatcatata ggctgctaat aacgcgattc cccacgctcc accttctccg
    15601 gctgtgtcca tcactgtaac tggtgcctcc atagcagatg ctagaatccg ctgtccaact
    15661 tctggtgttt taaaaatccc cccatgcccc actaaacgat caatttggac attctcagat
    15721 ttcaatatat ccattccgat tctcattgca ccaaaagcac tggctaaatg gatccgcatg
    15781 aaattcgcta aatcaaaacg gctacctggt gtacgtacaa ataatggcct tccttcattt
    15841 actcctgtaa tgttttcacc ggaaaaataa ccataagaaa gtaatccccc gcaatccgta
    15901 tcgccttcta gcgctttgtt gaataatacc gtgaataatt tatctctgct tatctccata
    15961 cccaaagaat tggtaaattc ttcaaaaata ctgacccaag cattgatatc cgaagagcag
    16021 ttattcgtat gaaccatgcc tactagttct cctgaaggtg tagtgaccat gtcgatttcc
    16081 ggatggacat tttctagttc tttttctaat acgatcatag cgaaggcgga agtaccagcc
    16141 gaaatgttcc ctgtcccttt ggctacactg ttcgtagcga ccataccggt tcctgcatcc
    16201 ccttctggcg gacaaaccgg gattcctggt ctcaaatttc ccgtagggtc gatcagataa
    16261 gcccctgatt cgcttaactt gccagcttct tctcctgcta ctagaacttt aggcaaaatg
    16321 tgatccaagt caatcgctac gtgcgctttt tcgattaact gaccaaaaat atttttcatt
    16381 tcttgatggt aggttttcgt tgaaggatcg ataggaaaca tgcctgatgc atctcctacg
    16441 cctagtactt tctcaccagt aagctgccaa tggacataac ctgcaagcgt tgtcaaaaaa
    16501 ttaatttctt tcacatgttc ttctttattc aaaatagatt gatacaaatg agcgatactc
    16561 catctctgcg gaatattgta ttgaaatttt tccgttaata ttcgttctgc ttcttcagtg
    16621 attgtatttc gccaagtacg aaatggtact agtaactgtt ccttgctatc aaatgctaga
    16681 taaccgtgca tcattgcact gaacccaatc gacccgattg tcgtaagatt ctcgccatag
    16741 atttcgaata cttctgctgc catttttcgg taactgacgc gcagtccttt ccaaatatct
    16801 tctaatgaat aggtccagat accattttct agtttgtttt cccactcata actaccagcg
    16861 gcaataggag taaaagatga atcaatcaat acagctttga tcctagttga tccaaactca
    16921 atccctaaag atgtacgacc atctatgaca tctaacatac tttgcgcatt tacttccttc
    16981 ataatgattt aactccctcc ttctcgtcaa acctgatcaa accgtctttt tagtagcgct
    17041 tacaatgatt attgtatact tttgtacgta catgtcaagc agttatttac aagaatacaa
    17101 taaaaaacac ttgttttgta cgtacataag ttataaaatg aaattgctta caaaatctga
    17161 tcaaccgcct tctcgaaatt ctagaaggag agaatactta tgaaaaaaga aaaaaaagtt
    17221 tcctcatcgt ttatttattt ttttggcgca tttggcggca ttctatttgg atatgatatt
    17281 ggtgttatga ccggcgcctt acctttttta cagcatgatt ggggtttggc aggtaaagct
    17341 tctttgatag gatggatcac gtcttcggtc atgttaggtg cgatccttgg cggctcttta
    17401 tctggtcttc tttctgataa gcttggacga cgaaaaatga ttcttctttc tgcacttatt
    17461 tttatggctg gttctgtcct ttctgcatct gcccctcaca atggttctta ttttctgatt
    17521 gcagcaagga ttcttctagg tttagctgtt ggcgctgcat ctgccctagt tcctgcttat
    17581 atgtctgaaa tggctcctgc tagactaagg ggaagattgt cagggatcaa tcaagtgatg
    17641 attgcttctg gcatgctcct ttcctatgtt gcagattatt tgctaaaagg gttgcctgaa
    17701 acgatggctt ggcgcgtgat gttagggctc gctgctgtcc ccgcgctgat tttatttttc
    17761 ggtgttttag ctctaccaga gtcaccgcgt tttcttatgc aatctggccg cttggaagag
    17821 gcaaaaagag tattgaacta tattcggaca ccaaaagaag ctgaacagga attcgaacaa
    17881 atccagctga atgtcaaaca agaaaagaca accggaactt cttggcatac tttgttttta
    17941 gaaaaatatc gttccttagt cattgccggt attggtgtag cagtattcca gcaatttcaa
    18001 ggagctaatg ctatttttta ctatattccg ctgatcgtag aaaaagcgac tgggcatgca
    18061 gcgagcgatg cattgatgtg gccgatcatc caaggaatca ttttagttgc tggttctttg
    18121 ctctttttgg ttattgcaga caagttcaat cggcgaactt tattgaaaat aggcggtagc
    18181 gtgatgggac tttctttcat cctaccagct gttttaggaa ctgtactgga tgctcataca
    18241 aattcgttgt tgattctctt gtttttatgt atttatgtcg cattttattc ttgcacatgg
    18301 gctccactga catgggtaat cgtaggcgaa atattcccac tagctgtccg cgggcgagca
    18361 tctggcctag cctcttcttt taattggatt ggttctttcc tagttggctt gctttttcct
    18421 gtgatgactg cttctatgtc tcaagaaatc gttttcggca tttttgggat catctgcttt
    18481 ttaggggttt tatttattca agagatcgta ccagaaactc gtgggaaatc tttagaggaa
    18541 atcgaacaaa gtgcatctaa aaaaacttat cctaaacgta tttctatcca tcattcttaa
    18601 agaggttgtg acagaagtgg tcagcttcaa gaaataagaa ggaaccgctt agtttccagt
    18661 cacaaggaac aatttcaaaa aacagcttct catgtttgat gaatattgtg acttgtgacc
    18721 agttggtagg agaacaccgt ttagtggaga ggtggtgaaa gaaacgttca gccttgagcg
    18781 atgacaaaag ctctcacaaa cattgcgacg agtaaccgta ggagcaataa gaggcggtaa
    18841 aaacccgtct cttatttttc gttttctttc actgtttccc gttcaactag tacaggttca
    18901 tagagaatat ttggctgtgc ctgtcctttt tcaatcgttg tgacgatcca ccgtgcggca
    18961 tcttgtccca acttttcttt tggatgcgtc aatgttgtca attttttatt ccctaaatgg
    19021 cttaaagaag aatcgtctgt tcctacgatc gataggtcat ctggaatatg atagccattt
    19081 tctgtcaact tatctagcat taaactagct atttgatcgt tatagcaaat gatgccatct
    19141 aaagcttgtt cttctttcaa ccgttgtact gttttttcag cgattgtttc tcgtgtttcc
    19201 gtggtgaaag taatgatatc ttccgtcaaa aaacgcacat tatactgttc acacgcgctg
    19261 ataaaacctt tcatcctgta ttttccttga agatcgtcga tttttgtgat gaacaacaga
    19321 cgctgatgtc ctttttttat caaatattct gctgccataa aaccgacttt cacatcatct
    19381 aaacaaatat aagaggcatt taactcttca taagcagcat tgatcatcac catcggaatg
    19441 ccttgttctc tcaaagcaac ataaagtgct aagtttgggt tatactgatt acttttcgta
    19501 ggctcaacga tcaaaccatc taccccataa gcaatcattt tcttcaaaca ctctttctcc
    19561 aattcgtgat cgttattcgt actggctaaa agcaatgaat acccagattc tcgtaattca
    19621 ttttcgattc ctcggataat cgacggaaaa atataatcag agagatatgt ggtgatgaca
    19681 ccgatcgttt ttgttctgtt caatggtgtt ttttctttct tatagctgtc atctacatat
    19741 gtgcccgacc ctttttcttt acgcagatag ccctcattta ccaacacagc gattgcttgc
    19801 cgaatcgtat gtctgctgac gtcatatatt tcttgcagct tgaattctga gggaatggtt
    19861 gtatttactt cgtattcctc acgaaggatc ttttgtttta tctcttctgc aatatcttga
    19921 tattttgcca tttgccttgc ccctttttat ttgtacgtac atatatcata acgagtctgc
    19981 aaggtttatt caagcaaaaa tcaaggtttc ttgtgctcat aaggcatacg gaacaggttc
    20041 accaaattct ggaaatcctt gctcattcca cgtaaagcat tgcgcgttcg cgtgccgatt
    20101 aggattgtct aacggatccc ctttttggtt cttctctggt cgagcatgat agatcaaagt
    20161 atcaaagcac ccgtcttctg aaaccgtaaa cgagttgtga ccaggaccaa attgcttatt
    20221 tttttcagaa gaaacgaata ctggctccga taatttatgc catgattctt ttaataaaag
    20281 attcttgtgc tcatcagccc acagcaggcc catggcatag ttttcatctg ttgcactacc
    20341 agaatacgta atgaatattt tcccattgcg agtaaggact gctggacctt catttactga
    20401 aaaaccccgt ttttcccatt catactcagg tatagaaagg aggatctgct tcccctttaa
    20461 cgtccaagga ttatccattt cggatagata aagattagaa ttcccagtaa tttcaggatc
    20521 ttgttgggcc cacacataat atagctttcc ttgagaagag aaagttgttc cgtctaaact
    20581 gaaagtttcc cttttcgttt ttatttgtcc cttttctatc caatctgtat tcattggatc
    20641 tatatgctga ttttcaagta cgaacatgcg gtgatgatga gattcatcac gtatagtttt
    20701 atgattgctt gcagcaaagt aaatatacca ttttccattg atataatgga cttcaggtgc
    20761 ccagatcaat tcactcatcg gtccttcttc atgagcctgc catacaatca ggcttgcagc
    20821 atgttctaat tcattcagtg actttgccct tcttaattca atcacttggt agcctggaac
    20881 cgatcctgta aaataataat aaccatctgt atgtttatat acccaaggat ctgcccgttg
    20941 ccgaacgata ggattattat aaagtgtctt catcataaca aatttcctca cattttcttt
    21001 attctaatta cattccaaga gtatttttct atccctacat ttaattcgtc atgtttttct
    21061 attgaaaaat agtttatttc aggttttatt ttttctggtt cttcacgtgt atttttgtcc
    21121 aacagatcgc tactggttaa tgtgtagtgc tctccttgat ctagcaaatt gaaatcatgt
    21181 tcaatcgtta tcttttgttg ttcatttgtg cgattgatca agaaaatagt cagctgattg
    21241 ccgttatcta cgatcacact gtccacataa ggaacatttt ttatcttttc acaatcataa
    21301 acagggcaaa tgatttgttg tttcaatact tgacctttag catatttcga taagtgttgc
    21361 atcacataat aagttggatt cctccatgct tgtcctttag catctgtcag tattaaaggt
    21421 attgtgttta ctaacaatga ttgacaacta atctttacgc gatctgcgtg tcgtaaaata
    21481 gccagcccta atgaaccaaa taataatgta tcttccatag taaagtaaca ccaatcgatg
    21541 ggactaccga cttcaaaatc cctatgtctt ttttccggtt gggcatgtac attccattca
    21601 tcaaacgcta gatacattgt tttctcactt ctcaaatatc cttttacata atcacaagta
    21661 gcaacgattt cttcaatttg acgatcgaat cgataagctt ttgcaaggta tgtcgctgta
    21721 tcatcacgct catttttagg aggtttagtc aagtcttctt catcatactt atcaatatag
    21781 ttatgcaaag ctaaataatc tacattctca taagcttctt ctaatgcgat acgatcccat
    21841 tcagggtacg atggtaaacg tggcgtagag cttccaacta agattgtttc aattgaatca
    21901 tccactaact tcatgacttt tgaggcttca tttgctaacc taccatattc ataagcactc
    21961 ttagccccca cttgccatgg accgtctagc tcattcccta aacaccataa tttaacgcca
    22021 aaaggctttt tttgcccatt ttttattctt aaatcactcc agaaggttcc ttttggaaaa
    22081 ttacaatatt ctactaaatt ttttgcttca tcaattcctt ttgttcctaa attcaccgtg
    22141 aatatcggtt tcgcttgtac atgactgatc catttaaaaa attcgtggag tccaaaagaa
    22201 tttggttcta tacctcgcca tgctaaatca attttttttg gtcgttgttc tttcctacct
    22261 acagtatcca cccaatcata accagatgta aagtttcctc caggatagcg aatgacacct
    22321 aattctaatt cctttacata agagaggaca tcttgtctaa acccgtcacc atcagctgtt
    22381 tcatggcccg gttcataaat ccctgtatag acgacacttc ccatatgctc aacaaatgag
    22441 ccaaacagcc gagaactgat ctctcctacc gtaaaatcct ctctgatttt tactttcact
    22501 tcttcgtcca acagctttcc ctacctttca tttcctatag tcaagataat agatacaagt
    22561 ttccatacgc caccagcaaa gataaaaata aaaggaggga aaagaaatat gagcagtaca
    22621 aatcctaata acaatacgca acaaagaata tttctcaaaa aatcaaaaaa tactttccat
    22681 gcactttgtt caaaaatttg taaaaatgtg atatctttgt tttcagaaat cacatatatc
    22741 caggataaaa gaaacatgga ataaataagt aaaactacat atccactaat tgaaagtacg
    22801 attgtctgtt cttctaataa ttgattaaca agaaaataaa taatgatcgt taacagacta
    22861 aggaacaagt tcttaccaaa atgttgcttt attccttgaa agaaaaaata aatgatattt
    22921 cctgatccct cacctttcca ttgcgccatt acataaaaaa cagcacatgt agcaggcacg
    22981 atagtaataa caggcaaaca cacgattacc cagagaatac ctaataagat gtaatcagaa
    23041 accacaatca actgtccata aagtttagtc tcaactattt tcatcttcct cactctttca
    23101 ttccagacat agctgttcct tgaacaaaat atttctgtgc aaaaatataa accactagta
    23161 atggcagcat tgaaataacc gttccagcca ttacaggtcc ataaaaagaa atgttctgcc
    23221 ctgtaaataa agctaaccct gctggtaaag ttctcatttt tgaactactt gtcaatatca
    23281 atggataaag caagtcattc caactattca tcagcgtgaa aatccctaat gataaaagag
    23341 taggtttgct caatggcaac atgattttca aaaaaatatt aaactcactt aatccatcaa
    23401 tgcgtgctgc ctcttccaaa gaatctggta aagtaataaa aaaggaacgc atcatgaaga
    23461 taccaaatgc agttgtcata cgaggaatga tcaaacctgc ataagtatca agcatgccaa
    23521 gcaaattgac ttcaataaat agaggaatca tgaagacttg gaatgggatc atcattgtca
    23581 gcaaaacgaa atagaacaaa actgattttc ctttgaaacg catacgagca aatgcatacc
    23641 ccgcaagaga atcaaagaat acagaagtga tcactgtccc tccagcaaaa atcactgtat
    23701 ttttgatgta atctaataaa gggatcgttg tccaaacctt aatatagtta tctagggtat
    23761 agctatctgc aaatattcta ggcggaaatg agataatgtc tttttcgtgt ttaaaagaag
    23821 aaataatcag ccacaaaaaa ggaaacgcaa taaccaacaa tataactagc atactaatcg
    23881 ttcgaatgat ttttttacca ctaactgctt ttcgactatt cacagtaact gtaatcgagc
    23941 tttctggtgc catacaggtt tccctcctat ttcatttgtt tttctttccg tgacatgtac
    24001 acattagtgg agatagctat agttgcaaca atgataaaca aaaccgaaga cagtgctgat
    24061 gcatagccca attcataagg tgctgtaaat cctcgactgt aaatatattg aacagctgtt
    24121 tctgtcttaa attgtgggcc accagcggtt gcaacatata cttggtcaaa cacttgcatc
    24181 gaaccaatca gattcgttaa aatacaaaaa cctaaggagg gaacgatctg aggtagcgta
    24241 atgttaaaaa actgctgtcg atttgttgca ccatccattt gagcagattc atacaaagag
    24301 ggagagattc cctgaatagc agtcaagaga atcgtcatag taacaccaaa attcttccaa
    24361 acagtcatga tggctaccgt cggcatagca agggttggat cgcgaaaaaa ttgagggatc
    24421 ggcaagccga cttgtgaaaa caagtaagga atcgccccta cattcggatc aagcaacata
    24481 gaaaaaataa tcgcaattga cgtcaatgaa caaataactg gaatgtaaaa tgtcgaacga
    24541 caaaaacgat tgaatctggt atttttagat aatgctactg ctgctaataa accaacgata
    24601 atttgtgttg gcgtttcgag tacggtgaaa tataaagaat gaatcaacga attaactgct
    24661 cgttcatcac taaatatacg tgtgaaattt tcaaaactta caaaatttct tgatgtaaag
    24721 aaaatattca aatctgtaaa actaatagca aatgttccta aaagcggtat gacagtaaat
    24781 aataataaaa ctaaaaaaga tggagttaaa aacaaatacg cagcacgatc aggacgattc
    24841 caatatttgg tgaatccgtt catatagtcc acctcatctt tcattttgat aaaatataca
    24901 atcttggttt aaacgaatct gaataagata tccgaacaat cgctgtgatt tttgcaataa
    24961 cacctatctg caaatactag gtcgatcatt cagatatctg tatcttgcca acagtctatc
    25021 ctgtataaag ttctgtacta tttttgcagt aattgattga tggcatcatc tgcatcgttc
    25081 atgagtgtct caggatcttc tcctgctaat aatttttcaa tcagtggatt gatgatatcg
    25141 ttattgatcg cagagatttg ggtaaaacct ggtaaatatg gctctgcata gtccatttgt
    25201 ttcgataatt cagatacaat aggatcattt tttacttctt catcttttgc tactgaatcc
    25261 aagtaggcag gaaaaccatt ttcgatactc cattttttac caatttcagt tgtattccaa
    25321 tatttcaaaa actcatagac agcttctttt ttattattat ctgtacttgc cggaatggca
    25381 tatcctacgc catctaaaat agctgttttt ttgtctgaat cactcccttg tggtaaggta
    25441 gtcacattat aatcaatctc gtttgctttc aatccgttat ttaaccatgg cccattgatt
    25501 tcaatggcta gttgaccagc attcattaaa ttgtccattt cggcgccaga aatcgattct
    25561 ggaccagtct tgtctacatg gatcattttt tggatcgctt ttaacgtttt aaggttctca
    25621 ggagacgcaa attcagactt agtataatca tcgttcacta atttaccgcc atttgctaac
    25681 atccagttat ataacggtgc agttccatcc ttattgaaga caaaacctga tacattttta
    25741 ctactatcag ttaattttgg tgccatttct gtcaattctt cccaagtagt aggtggttgt
    25801 tcagtatcta atccagcttg tttaaacaaa tcattattcc aatacatata catgccttgt
    25861 acctgcatgg ggacaaaata ctgtttacct tctacttcac ctaattcaat agccgtttct
    25921 ttaaaatcag atttatctac tccatcatat tcccagaaat cgtctaatgg ttgtaccgct
    25981 ccgttttcta catactgtgc aaaatctgga taatttaatg caataaagtc aggtgctttt
    26041 ttagaagaaa tcgctgtagg aagtttttca ttcaaattgg cccaagtcat gatatccatt
    26101 tcaattttga tgtttttatc atttgtttta ttaaattcat taacgatttc ttgcaatatt
    26161 tcaccatcag atgcagtaaa cccattccaa aaagtcaaag tcacttcttt atcagaatca
    26221 gattctgctg aacttccgcc accgcaagct cctaaaatac ctgttgcagc taccaacaaa
    26281 gagccaatta accatttttt acctttcatt ttttgttcct ccttcatctg ataaacgaca
    26341 tctgaccaca ttccaagata gcggtttcaa taaacaattg attttcccat cttcagcttt
    26401 tacatttgtt gaatgacttg gttttacttg ttcactttta ggaagattag ttgcttttgt
    26461 atcaaatcca ctcatttcag aaaaatcaat cactccctct aatgataatt cagacaagtg
    26521 aacagttaga ttcatttctt cttctccacg gttaactgca aatatgacaa gttctttgtc
    26581 atttattacg gctatacttt ctaaatacgg cacttcttca aaatcttccg tcgcatagtt
    26641 tgctgaacga atttgtgggc ttaacacctc tccttgtcca tacacagcag cttgcataaa
    26701 tggataatag atcgtctgtc tccaagcttc tccgtttgtt tctgtcctga ttggtgcaat
    26761 aacatttacc aattgagcaa gacaagcaat ctttactcta tctgcatgtt tcaataaagt
    26821 gattaataga cagcctaata gtaatgcatc ttcaaaatta tagttatctt ctagtaaagg
    26881 aggagcaatc tgccaaggcg ctgcttgctc atcttgttcc gctgaatgat accaaatatt
    26941 ccattcatca aaggacaggt tgatctgctt cttactatgt ttcttcgcct tgactgtatc
    27001 gcacatcgct gtcacttcag aaatgaaccg atccatgtct aaggaacgtg caagataatg
    27061 agaaagatca tttttttggt tgccataata ttgatgcaga gacaaataat ctatttgatc
    27121 gtacgcttga tcaagaactg ttaactccca atcaccaaat gtaggcattt gccgattcga
    27181 acttccgcat aaaaccacct caattgaatc atctacgagt ttcatcgcct tagccgtttc
    27241 ctctgctaac cgtccatatt cttccgctgt tttatgtcca atctgccaag gaccgtccat
    27301 ttcattccct aaacaccatg tcttaattcc aaaagggctc tcttgaccat tcgaacgcct
    27361 taaatcactc caataagttc ctttaggaaa attacaatat tcgactaaat tacgagctgc
    27421 atctactcca cgagtaccca gattgacagc catattgatt tcggccccca catgctgaca
    27481 ccagttataa aattcatgaa tcccaacttc attcgtttca attgtccgcc aagctaaatc
    27541 caaccttcta ggtctatttg ctatgggccc aatactgtct tcccaacgaa atcctgacac
    27601 aaaatttcca ccaggatatc taatcatggg aatgttcaat tcttttacca agtgaatgac
    27661 gtcttggcga aatccacttt tattagctga tggatgatct ggctgataaa tcccttcata
    27721 tactgctcgt cccatatgtt caataaatga actgtacaac cgcggatcaa ctttgcctac
    27781 acgcttgaca ctactaatca acattgtggc ttccataact gacctccttt aatttataca
    27841 tgaataatac acctcgttga aagcgttgtc aataatataa atgttaaact tacttatttt
    27901 ttatcgattt taattaacca aaatattaat aatgattaaa acaaataatt taatataact
    27961 tttattaaca aatatgttaa tatataagaa aaacctttta agaggtgata tatatgcaac
    28021 tacaaataaa cgaagaatcc ttaccggtat atgaagcatt agctagtaaa acaaggatca
    28081 agatcatcca gctactttcc aaaaaaaaga tgaatgtcaa agatttggca aaagaacttg
    28141 gagtgagcag tgctatcacg acgatgcacg tgaaaaagct agaggaagca aacatcatca
    28201 aaacagaaaa agtaggacaa caaaaaattt cgagccttcg tgtcgataaa atcgatatca
    28261 gttttccaga aaaaatattc aatgcttttg atacgaaaga aacatcgata cctattggtc
    28321 actatacaaa ttatgcaatt gaaccaacat gcggtttagc tacgatccat gattttatcg
    28381 ggaaagtgga tgaaccacgc tattttatgg atcctcgaag gatggatgcc cgcattctct
    28441 ggtttaccag cggatttgtc gagtatcagg cacctaattt tttaaataca gaggatacat
    28501 tggagatgtt ggaagtttct gtggaaattt cttctgaatt tcctttttca aatgacaatt
    28561 ggccttcaga tatcactttc agcctaaatg gtgtggagct aggaacatgg acgagccctg
    28621 gagattttgc tgatatccgc ggtaaatata cgcctgattg gtatccagat aatcttaatc
    28681 aatacggctt gctgaagacg atccgaatta ccaaacactt gacgaatatg aatggagaac
    28741 ccttgtcaaa catcacgatc aacgacatcc ctaaagagca agacacttgg catttgcgaa
    28801 tcgaagtgaa agacgatgcc aaacatgtgg ggggctgtac tttatttggt aaaggattcg
    28861 gtaattacga tcaggatatc aaattaaaag tttactacag ctgatatttt tcttttctat
    28921 tttataaaac aaaaacagcc aatccctatg aagggacggc tgtttttgct ttattgttat
    28981 ttccagaaat catccaaaac ggaaattggc aaatgtcgtt tatgttgtgt cttgttccac
    29041 catgcttcga ttttttcttg tgcttgagcg ggaacttctt ttccttctag ataatcatca
    29101 atttcattat atgtgacacc tagtgcgact tcatctgcaa tcattggttt cccatcttca
    29161 agatctgcag tcggaatttt tgtgtataat ttttccggtg cattcaatgc ttgaagcaat
    29221 tgtttccctt gtcgtttgtc caaacggaat aatggcaaaa tgtcggctcc accatcacca
    29281 aatttcgtga agaatccagt aatgttttct gcagcatgat ctgtccctaa tacggctcct
    29341 gctctttctc cagctacggc atattgcgta atcatacgtt gacgtgcttt gatatttcct
    29401 ttgttaaaat cgctgattcc cacacctgct tcgcttaata cttgtacttg tgcatcaaca
    29461 gctggtttga tatttactcg cagactaaca tcgggctgga taaagtcaag agcagctttt
    29521 gcatcttctt catctgcttg ttcaccataa ggaagacgaa cagcgataaa ttgatagttt
    29581 tcatcttttg tttcttcacg catttcttcc atcgttagtt gcgccaaacg gcctgctaaa
    29641 gtagaatctt ggccgccgct gatacctagt acaaaagttt taagaaacgg atattttttc
    29701 aaatatgctt tcataaagtc aatactttta cgtatttctt cttttggatc aattgttggt
    29761 ttgacaccta attcattgat aatttctgtc tgcaggctca tttattctcc tcctatgctt
    29821 ctgtatgaag ttctgctacg ctttttttca ttcgttccat gatagccatt ttatggttcc
    29881 agcattcagt agacagatcg actgggtatt tttgcggatt caagtctcgt ttatactctt
    29941 cccatagtga atctagattt tcttttgtat attctttgat ttcgtttagt gcaggtaatt
    30001 cgtaaactct ttttccttcg ataaagatat cttgtaaaac tgggcgagct gtaaagtctc
    30061 gaacagtttt attgataaac gtatgcactg gatggaacat gaagatagct tcttcttctc
    30121 gagggtcttc atcccataat gtcacgtagt ctccttcaga tttcccatca aaatttcgag
    30181 tgatgcgcca cacttgtttt ttccctggag tagttacttt ttctgcattg cttgataact
    30241 tgatcgtatc catcattttt ccttcatcat cttcgatcga tactagcttg aatactgcac
    30301 caagggctgg ctgatcatag gctgtgatca attttgtccc aacaccccat acatcaattt
    30361 tagctttttg catctttaaa ttcaaaatcg ttgcttcatc caagtcattc gaagcataga
    30421 tttttgcttc cgtaaatccg gctgcatcta attgttcccg aacacgctta gatatatagg
    30481 ccatatctcc actgtcgatg cgtacgcctt ggaagttgat tttgtcacct aattctttcg
    30541 ccacgcgaat cgcacttggc acacctgatt tcaacgtatc ataagtgtcg actaagaaca
    30601 cgcagtcttt atgggtttta gcgtaggcca taaatgcttc ataatcattt ccataagatt
    30661 ggactaacga atgagcatgg gtcccgctag ctggtatccc aaatatcttc ccagcacgta
    30721 cattgcttgt tgcatctgct ccgccgatat atgccgctct agttccccag actgctgcat
    30781 ccagttcttg tgcccgtcta gttccaaatt ccaatagtgg atcttctccg atgacagatt
    30841 tgatacgagc tgcttttgtc gcgatcaacg tttggaaatt gaccatattc aacagtgctg
    30901 tttctactaa ttggcagtgc gctaaaggcc cttccacttg gattaatggt tcatttgcaa
    30961 aaactagttc tccttcacga gcagaacgaa ctgttgcttt aaattcaaaa ttttgtaaat
    31021 actccaaaaa accttcagga tagacttcta atccacgcaa gtaagcaata tcggaatcat
    31081 tgaacgtcag attctctaaa taattgacta accgttccaa tcctgcaaaa accgcgtatc
    31141 cgtggttaaa aggcatttct cgaaagtaac attcaaaaac agcatgtaaa tcagctcgac
    31201 ctaattccca gtatgtctgc atcatattga tttgatatag atccgtatgc agcgtcaaac
    31261 tgtcgtctgg gtaagtatta ttcatcttgt attactcctc ttggcaagtt ttcatttcct
    31321 acccattata acaaaaaaaa ttaataggaa aagaaatctt ccattttttc tgaaaaagca
    31381 catgttttac ggatatttct tgctaaaaat gaactccatc tgctaaaact atcctttctt
    31441 attggtattt aacctaaacg agaaagaata cttattttat tcaatgtatc cgagacacga
    31501 agaaattagc gttttctatt tttcttactt gataaaataa gtagattttc ctactacaat
    31561 cgtagccgtt aagataccga tgattgaaca aatataacca aatgtctcta caacataatc
    31621 aatggcaaaa gtttttgaag caataatacg tctttccttt tttgcttctt atccccaaag
    31681 aaacggatat aacttattat gtattgaatt tttttggaaa ggcgaattat gacaagatat
    31741 accttgcgtt gaaaaaactc gcggaaaaaa tatcacacgt ttttaaaaag atacaaagta
    31801 agaaagcagc tgtcaataga atggaaacaa aaatggcgag acatcaatca gtctcgcctt
    31861 gttttttatt gtatacatta gatatggagc aggttaccat aaagatgatt attagtcgtt
    31921 attaaataga atccttcgta tttttttgtt ctatcactac aatatcttta tttggacgtt
    31981 tgaattgtat tccggcacgt tctagctcct gtttcactcc tacatggact ttgacatctt
    32041 ctcgtgtcat ttttaaaacg tgatgaatcg catagtcgat ttcttgcctt gtgatttttt
    32101 tcttcgtatt gatcatcacg acttgctttt tatcatatgt gtctaccaat agcagttgtg
    32161 ttcgatctaa cgaaaataat ttgtaataat taatagccgt attcccaaaa aagaattcca
    32221 ctactttagg ataaaatgtc ttaatattta aattactatt cacaggtgtt tcgattagct
    32281 tcatctcatt cctcttttct atatagtcga tttagatcca atcttaagtt atgttaccat
    32341 ctttcctagc attaaggaat cggttacaat tgaaccttta aagacaaaag gatttacctt
    32401 ttatcactta atagtataac ataatttcgt gagaaaaaaa tacaattttt tcttgaccat
    32461 ctcgttacgt aaaggattat gcttacattt gtcaggagga aaaataatgg agtacacaat
    32521 aaagaaaatg tcagagatat caggagtcag tccgagaacc ttgcgctttt atgatgagat
    32581 tggactgcta aaaccagcta ggatcaattc ttcaggttat cggatttatg gcaaaaaaga
    32641 agtcgatcgt ctgcaacaca tcttatttta tcgaacaatg gcattcaagt tggatgatat
    32701 ccaagaggtc ttagacaatc catcttttga ccaccagaaa gctttaatca agcatcagca
    32761 aatgttgctg gaaaaacggg cacaaatcga taccctcttg acaactgtcc aacagacact
    32821 tgatatgtac gaaggaggaa gaaaaatgag tgacaaagaa aaatttgaag ggtttaaaca
    32881 acaaaagttg aaagaaaatg aagaatccta tggacaagag attcgacaaa aatacggaaa
    32941 aaaaaaggtt acagcatcca atgaaaaatg gatgaatatg gataaagaaa cgtatgaaga
    33001 aatgcaaact gttgaaaagc agatgttatt tgatctcact ctttacttaa aagaaccaga
    33061 agatgaaagc ttagcagacc gtatcttcca agctcataag aagtggttct cttacagctg
    33121 gcctgaatat cagccaaaag cgcataaagg actaggaatg atgtacgaag ccgatgaacg
    33181 gttcactgca tattatgacg agcgaagtgg tcatggtgca gcaaaagctt taaatgaaat
    33241 tatccaaaaa aaggcgtaat cttttacatg atccaacaaa aaagtacacg taaaatgacc
    33301 taataacaaa acagcagaca cccaagttag atttttatgc taacttttgg tgtctgctcc
    33361 attctttcac aagttttttc atcctacttt aaatatattc atcgttgaat aaacgtataa
    33421 ggtattttca ctttatcctt tttttctgta agaaacaatt gaaatgccat ttctccgcaa
    33481 gcttccagat ggtggtcgat ggttgggaaa ccaagaagct cgctgatcag caaattatcg
    33541 cgtccaatca ccactggtgt cttatcttgc agatagcttt gcaagatgcc tgctgcaacc
    33601 atatccgaat ttgtaaagac accatcaact ccaagctctt taaaaaagaa gcctgcttgt
    33661 tttcctttct ctgcatctat acaatcccaa aaaacaagtg attcatcaaa agatggaaaa
    33721 agttgatgac atagctgcaa agtgattttt gagttataac ttagcctgcc acttcgcccc
    33781 aacgtgatgc ccaattgctt tataccttgc tgcttcaaat aagtaagacc ttctgtaatt
    33841 gattgttctc gatcaataaa gacacagctt gcctgttttc ccttgatttc ttcacaaaaa
    33901 actagaggtc catatttttg atatgccaat aaatcatcta gtgtattggc acgagacgta
    33961 atgatcaatc catcgaaagc tttagctgca aattcttcaa gataccttcg ctctttttct
    34021 ttatgatagc ccgtcggtaa aagtgtcact ttgtaatcat aatcaaacgc tgcttcaatg
    34081 atcccactga tcaactgatc aaaatacgga tgattggtat aaggcagaat cactccaatg
    34141 cttttcgttt ttccataact taactgtctg gcatttgcat tagggatata atcgacttct
    34201 ttcatgaccg caagtatttc tttccttttt tcctcatcta catatggatg tccattgatt
    34261 acacgtgaaa tagtagaaac tgaataacct gtgagctttg cgatatctcg aatgtttgcc
    34321 actgctgctt cgccacctat acaaaaagat tttcttgtaa atagtctacc acagctggac
    34381 cgcattcaaa aaactgatac atttttcctt catgcgaaaa actgatccgc tgcccgcccc
    34441 aatatatatc ttttgtcaaa ttttcgattt cattcattgg tatttctttt actatattcc
    34501 tattcaaccc ttgaaaactg tacaacgtta atacggatcc cttgaactcg acaaacgcat
    34561 aaaaataatt gttcgttgtg ccatctgtta tctctacata agtattcatt gcaagccctc
    34621 cttttgatac tttgagtata gtgtatgaaa cgcgtctcat agcaaggagt ttgttttgcc
    34681 aaagaaaagt tttattcctc tttcattatt accaaagtct cttattttaa attgaataca
    34741 ttataatgat actgtaaata tatctttatt attagtgaat
//
LOCUS       DACDAF010000020        32867 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.020, whole genome shotgun sequence.
ACCESSION   DACDAF010000020 DACDAF010000000
VERSION     DACDAF010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32867)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32867)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32867
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.020"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(77..149)
                     /locus_tag="IVZ69_000913"
     tRNA            complement(77..149)
                     /locus_tag="IVZ69_000913"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="IVZ69_000914"
     CDS             530..1099
                     /locus_tag="IVZ69_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HAP8183019.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="IVZ69_000915"
     CDS             1086..1946
                     /locus_tag="IVZ69_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP8183020.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="IVZ69_000916"
     CDS             2136..2840
                     /locus_tag="IVZ69_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8183021.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="IVZ69_000917"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="IVZ69_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HAP8183022.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="IVZ69_000918"
     CDS             4677..5993
                     /locus_tag="IVZ69_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183023.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="IVZ69_000919"
     CDS             5994..6863
                     /locus_tag="IVZ69_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183024.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="IVZ69_000920"
     CDS             6918..7727
                     /locus_tag="IVZ69_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP8183025.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="IVZ69_000921"
     CDS             complement(7830..8459)
                     /locus_tag="IVZ69_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HAP8183026.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="IVZ69_000922"
     CDS             8629..9921
                     /locus_tag="IVZ69_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8183027.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="IVZ69_000923"
     CDS             complement(9997..10659)
                     /locus_tag="IVZ69_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP8183028.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /locus_tag="IVZ69_000924"
     CDS             10884..11168
                     /locus_tag="IVZ69_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HAP8183029.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="IVZ69_000925"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="IVZ69_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HAP8183030.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
     gene            complement(12933..14081)
                     /locus_tag="IVZ69_000926"
     CDS             complement(12933..14081)
                     /locus_tag="IVZ69_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8183031.1"
                     /translation="MLKVWVEQTKDGRFKFIERYVDPYTEKTRKKSTTLTSNSPQAWK
                     KAQKILDKKIKEALEDYNKSDITFGELYKEWYEYYKQHVKRTSYLKVPMMMKHVSKHI
                     SDDTIVRNIDETLINKIIEDMYTFGDLSLNYTKQTKTTLSVMLNYAIDRKYIQRNPAL
                     AVKIHPKKVEEEKRRLSMNKKYLEKEEIDQILKQLYSNPRRKLHGIIAEFLYLTGLRY
                     GELLALQMKDYEDGKISINGTLDYTSVKMDNAIKTTPKNTYSQREVQLPNRAKELIES
                     VIADNILAGRPTDPDQYIFISTSGTPLALHSFNAILHKVEEELELEKSLSSHIFRHSH
                     VSLLSELGVPLKAIMERVGHSDANTTLSIYNHVTKRAKQQVIDKLNSL"
     gene            complement(14180..14485)
                     /locus_tag="IVZ69_000927"
     CDS             complement(14180..14485)
                     /locus_tag="IVZ69_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183032.1"
                     /translation="MEKNLGQHIITCKNCGSNRVSVTSPRSNGCMLFFIGLMLLSFGF
                     WIPIIGWLIMIPLGGIMMLLSFFVPLLQKNYSVTCKACDNKFEVSKKQYQKYIKEIK"
     gene            complement(14572..14994)
                     /locus_tag="IVZ69_000928"
     CDS             complement(14572..14994)
                     /locus_tag="IVZ69_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP8183033.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFETEADKIAIMILLNIFIENELTDE
                     TQFKLENFMKFYSINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            complement(15012..15332)
                     /locus_tag="IVZ69_000929"
     CDS             complement(15012..15332)
                     /locus_tag="IVZ69_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8183034.1"
                     /translation="MITFERIKELAKKQGKSLNKVEEDLGYGKNVLYRLKNSNPSTER
                     LQEIADYFDVSVDYLLGREEKEAPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            complement(15780..15968)
                     /locus_tag="IVZ69_000930"
     CDS             complement(15780..15968)
                     /locus_tag="IVZ69_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183035.1"
                     /translation="MSRKTSVKISGDLEKIIKSEANKILKKGVDYTCPSCGKKIKISS
                     GKNKCKYCGAEIDFKGKV"
     gene            complement(16155..16406)
                     /locus_tag="IVZ69_000931"
     CDS             complement(16155..16406)
                     /locus_tag="IVZ69_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183036.1"
                     /translation="MKDYKLDFQSELPIEFVNEFKIEAPDKTRTLFTFNHDMILQEFE
                     DDTVICVARDSEFLTIYSNRKFNQTIPVRSKKVIIYFEE"
     gene            16482..17228
                     /locus_tag="IVZ69_000932"
     CDS             16482..17228
                     /locus_tag="IVZ69_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAP8183037.1"
                     /translation="MNTPQIFNFEQNEVRTFLENDIPYFVANDVAKTLGYKNPSDATN
                     KHCKKAVKTWGSDSLGRRQSFKVIPESDVYRLIIKSNLPSAEKFEAWVMEEVLPTIRK
                     TGSYSNVPQSFAQALRLAADLEEKNQLLEQQIAEYEPKISYLDTILSSTDTVATSQIA
                     ADYGMSAIALNKLLNELGVQHKVSGQWILYRKHMNQGYTKSHTSEIPKADGGTKVVMN
                     TKWTQKGRVFIYNLLIAEGYYPQMDLEEIG"
     gene            17243..17446
                     /locus_tag="IVZ69_000933"
     CDS             17243..17446
                     /locus_tag="IVZ69_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8183038.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            17461..17760
                     /locus_tag="IVZ69_000934"
     CDS             17461..17760
                     /locus_tag="IVZ69_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183039.1"
                     /translation="MKKPTLSELIEATEKAANPDDWYRQSLILEKFHGMSKTTLVEYC
                     KEMETIPEFSEGIVRPGHSTTFIHYHTFIWFLKWKDANKYRVKILSPSDVLKEAS"
     gene            17808..18092
                     /locus_tag="IVZ69_000935"
     CDS             17808..18092
                     /locus_tag="IVZ69_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183040.1"
                     /translation="MKITVPDELIADELTEQIVRKVLDALDERLKVMNKSVELPPYPN
                     KSEVKKVLGIGDDKLTHWINLGLKTQQWSKLDIRIERSELQRFLKENFEF"
     gene            18113..18301
                     /locus_tag="IVZ69_000936"
     CDS             18113..18301
                     /locus_tag="IVZ69_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183041.1"
                     /translation="MSYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            18627..18866
                     /locus_tag="IVZ69_000937"
     CDS             18627..18866
                     /locus_tag="IVZ69_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183042.1"
                     /translation="MENELSTLDQYLADPDWGKSNLQLVANKYEKSIDEAIVALTDAA
                     SITADDSKWTKRDLGILKRGVNWLEDQYREETKEK"
     gene            18872..19564
                     /locus_tag="IVZ69_000938"
     CDS             18872..19564
                     /locus_tag="IVZ69_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183043.1"
                     /translation="MFKPLIDSYSAVLKKFKGNDIGATINEEVNIERLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESSTTVSDANILANIILDFIFEHDIPFKNGYEILPQNEQYFFYKCLTNRVCCSCGKK
                     NADIHHVDSVGMGNNRKKINNSGRRFMALCRECHTKIHVEGFTTFTTKRKLTAVVLKD
                     SDLKRLGLNIIE"
     gene            19572..20087
                     /locus_tag="IVZ69_000939"
     CDS             19572..20087
                     /locus_tag="IVZ69_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP8183044.1"
                     /translation="MDIEGYEGVYQVSSLGRVKSNRPNYVINKGYVNKEGFIMKPSDN
                     GKGYQIIFLSGKGFRDRRYVHRLVAFHFLKEAYFEGAEVNHKNGDKSNNTVENLEWLS
                     SDDNKKHARKNGLTNLKGPSKLTDLQALAIKRLYTNKLMSSGEIMKLFNVSRHTVLNI
                     ASGKTFSFLED"
     gene            20196..21047
                     /locus_tag="IVZ69_000940"
     CDS             20196..21047
                     /locus_tag="IVZ69_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP8183045.1"
                     /translation="MADNKRYYYLKLKENFFDSDEMVLLESMPDGYIYSNILLKLYLR
                     SLKHEGKLMFNDRIPFNSTMLATITRHSVGVVEKAVQIFRDLQLIEVLDNGAIYMSDI
                     QSFIGKSSTEADRKRKYRKEIEEAKQNLITSGQMSDKCPDKTTPELEIELEKDIELEK
                     DIENVTPPKKSKAKPIRHKYGEYKNVLLSDEQMEKLKTEFPNDYQERIERLSEYCESS
                     GKTYKNYLATIRSWARKEKSEPKNASGAYKRTGRREKLPEWAIDQEAYQKKKALERAN
                     RQSKAPF"
     gene            21059..21328
                     /locus_tag="IVZ69_000941"
     CDS             21059..21328
                     /locus_tag="IVZ69_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183046.1"
                     /translation="MKIDYLELINEIASYKTGEEIEILRDVYEQLDEAGIERIKNDRS
                     SWSKLRYYFALYIDATQLRNLAYTKLLFADCVKGLQKHLSELEQV"
     gene            21490..21792
                     /locus_tag="IVZ69_000942"
     CDS             21490..21792
                     /locus_tag="IVZ69_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183047.1"
                     /translation="MNKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVTGTAEQLASLTGLHEKIVRKRARCGYTDVKKRTFRYVEGSS"
     gene            21789..21950
                     /locus_tag="IVZ69_000943"
     CDS             21789..21950
                     /locus_tag="IVZ69_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP8183048.1"
                     /translation="MTTEEVIQMRIRNIQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            21947..22258
                     /locus_tag="IVZ69_000944"
     CDS             21947..22258
                     /locus_tag="IVZ69_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183049.1"
                     /translation="MSVDKKAAMKRIIELTHSENWQEDKEIVAEVQKLGKSMWTEKPK
                     RKTPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEKK
                     C"
     gene            22252..22542
                     /locus_tag="IVZ69_000945"
     CDS             22252..22542
                     /locus_tag="IVZ69_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183050.1"
                     /translation="MLDMKIEDYRITSDSRNIVLSKVRRDEEGNIRYTEAKEESRADI
                     GYFQTVSSCLKAIQRDYVLSEERTIKSIIEYKKALENITRQFEQACEIEEEK"
     gene            22542..22853
                     /locus_tag="IVZ69_000946"
     CDS             22542..22853
                     /locus_tag="IVZ69_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183051.1"
                     /translation="MDELITKVEQWAKDKRLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLENS
                     E"
     gene            23020..23415
                     /locus_tag="IVZ69_000947"
     CDS             23020..23415
                     /locus_tag="IVZ69_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183052.1"
                     /translation="MIPRFRAWDKKTETIQEIESISFKEKKLVIDQKSVTWFNSDYIR
                     NSDEVELMQSTGLKDKNGVEIFEGDLVEHDDNLNGDWETFEACEVVYDKDYAQFCFKW
                     DAGNFLTDYRNLNVIGNIYENSELLEEQR"
     gene            23412..23969
                     /locus_tag="IVZ69_000948"
     CDS             23412..23969
                     /locus_tag="IVZ69_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HAP8183053.1"
                     /translation="MNKQEAIKKLESIKAIGNDAIAACYNESINSGITLMKKIDEPQK
                     PVIPQLVAGWLEKSTDPFTKAEKIAYLIKSKDGDSYYFCDWFVRDGIVTQEQGEELLA
                     WATRQSYETLLSLYNGYEVEKEPLWAIKNADGNYLTKCALWGKDGVNYSFECNPSHRL
                     LFTDKATADAAALLVNGTVEEVVER"
     gene            23966..24262
                     /locus_tag="IVZ69_000949"
     CDS             23966..24262
                     /locus_tag="IVZ69_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183054.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKSKFKVGDMVRCEA
                     EEFVYPFRGYVKKILSNSAIIRIENTMKCDRSTAKHKHYLAVARLVDMEVIKSK"
     gene            24339..24752
                     /locus_tag="IVZ69_000950"
     CDS             24339..24752
                     /locus_tag="IVZ69_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HAP8183055.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIETERDAILAALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGKIIAYK"
     gene            complement(25210..25485)
                     /locus_tag="IVZ69_000951"
     CDS             complement(25210..25485)
                     /locus_tag="IVZ69_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183056.1"
                     /translation="MYKPYMISYDLNNPGQKYDKVFEIIKEFGAYIKLQKSFWLVKTN
                     LNPNQMCEKLNTVLDNNDSLFICELQKNYQGRATEENWKFINEHIFS"
     gene            25939..26145
                     /locus_tag="IVZ69_000952"
     CDS             25939..26145
                     /locus_tag="IVZ69_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183057.1"
                     /translation="MLGQCFGNHARFDSLPATLNAYDGYDYRKKIVKKLYGATYGNVV
                     SVLSVHHQASVTVAEVEDAAVNGE"
     gene            26341..26508
                     /locus_tag="IVZ69_000953"
     CDS             26341..26508
                     /locus_tag="IVZ69_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP8183058.1"
                     /translation="MYRPQYLEQKYEVITVHKGNGEKVYEYRRPIKSDTYKRKENNEV
                     IPLYGKRIAKH"
     gene            26534..26878
                     /locus_tag="IVZ69_000954"
     CDS             26534..26878
                     /locus_tag="IVZ69_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HAP8183059.1"
                     /translation="MTEEFYRWLLQLTREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            26883..27164
                     /locus_tag="IVZ69_000955"
     CDS             26883..27164
                     /locus_tag="IVZ69_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183060.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            27267..27581
                     /locus_tag="IVZ69_000956"
     CDS             27267..27581
                     /locus_tag="IVZ69_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HAP8183061.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            27559..29253
                     /locus_tag="IVZ69_000957"
     CDS             27559..29253
                     /locus_tag="IVZ69_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HAP8183062.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            29273..30451
                     /locus_tag="IVZ69_000958"
     CDS             29273..30451
                     /locus_tag="IVZ69_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HAP8183063.1"
                     /translation="MGIFQKAVGYFTKKATVPLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            30414..31100
                     /locus_tag="IVZ69_000959"
     CDS             30414..31100
                     /locus_tag="IVZ69_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HAP8183064.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            31100..32260
                     /locus_tag="IVZ69_000960"
     CDS             31100..32260
                     /locus_tag="IVZ69_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HAP8183065.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            32270..>32867
                     /locus_tag="IVZ69_000961"
     CDS             32270..>32867
                     /locus_tag="IVZ69_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183066.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIQI"
BASE COUNT        11381 a         5314 c         6857 g         9315 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtagtaatta agaaagaacc ctattttaac agggttcttt cttctttttt tgttttattt
    12901 taagcaaaag gggcaaagaa ggggcaaaaa tatcaaaggc tatttagttt atcaattact
    12961 tgttgtttgg ctctttttgt tacatggtta taaatagaca gagttgtgtt tgcatcagaa
    13021 tgccctacac gctccataat ggctttaaga ggtacgccta attcagataa tagtgaaacg
    13081 tggctatgtc tgaatatatg tgaggataga cttttttcta attccaactc ttcctctact
    13141 ttatggagta tagcgttaaa tgagtgcagc gcaagcggag tgccacttgt agatataaat
    13201 atatattgat cgggatctgt gggtctacct gcaagaatat tgtcagctat cacactttca
    13261 atcaattctt ttgcacgatt gggtaattgc acttcacgtt gcgaataagt attttttgga
    13321 gttgttttta tagcattatc cattttcaca gatgtgtaat ctaaggtccc attaatggaa
    13381 attttcccat cctcatagtc cttcatttgc aaagctagca attccccata tctcaaacca
    13441 gttaaatata gaaactcagc tattatgccg tgtagttttc tgcgaggatt ggagtatagc
    13501 tgtttcagta tttgatcaat ttcttctttc tccagatatt ttttattcat agaaagcctt
    13561 cttttttctt cttccacttt tttaggatgg attttaactg ctagcgcagg gtttctttga
    13621 atgtattttc tatcgattgc atagtttagc ataacagata gagttgtttt tgtttgtttt
    13681 gtgtagttca gtgagaggtc accaaacgta tacatatctt caattatctt attaatgagt
    13741 gtctcatcaa tgtttctaac gatcgtatca tcgcttatgt gcttagaaac atgtttcatc
    13801 atcattggaa ccttcaaata gctagtacgt ttaacatgct gcttataata ttcataccat
    13861 tctttataca actcaccaaa agtgatatct gatttattgt aatcttcgag tgcttcttta
    13921 atttttttat ctagaatttt ctgagctttt ttccacgctt gtggtgaatt acttgtaagt
    13981 gttgtagatt ttttccgtgt tttttctgta taaggatcta catatctttc aataaacttg
    14041 aatcgcccat ctttggtttg ttcaacccac acttttaaca tctcctatca tttgctataa
    14101 taggcataac aaatagacct atataggttt gttttctaaa agcacgctct tactctggac
    14161 ggtggggcgt gttttattat tacttaattt ctttaatgta tttttggtat tgttttttag
    14221 aaacttcaaa cttattatca caggctttac acgtcacgct ataatttttt tgtaataaag
    14281 gaacaaaaaa agataatagc atcattattc ctcctaaagg aatcattatt aaccatccaa
    14341 ttataggaat ccaaaagccg aaacttagaa gcattagtcc tataaaaaaa agcatacaac
    14401 catttgatct aggggacgtt acagaaactc tgttactgcc acaattttta catgtaataa
    14461 tatgttgacc taaatttttt tccatcctaa ctctccattt ctatggtaaa atagatttga
    14521 ctttttaaat gaagtcgctc tcataagtcc gtgttgcagc acgggctttt tttactgtgc
    14581 ataagagtat tttttcttga aatatgactg gcaaacatta aaacattctg ttcttaactt
    14641 attattgata gagtagaact tcatgaaatt ttctaatttg aactgagttt catcagtcag
    14701 ttcgttctca ataaagatat ttagtaaaat cataattgca attttatcag cttcagtttc
    14761 gaattttgaa tgaaaagttg tagagttatc gtacagtact gaatattcaa aatgtgaagc
    14821 aatgaaatga ccgagctcgt gggctaaatg aaaagcttca gaactgtctt cgtgtagttt
    14881 ttcattcaaa aatactattc ttggttttgg ataataaaaa cctggttctt ccatttccat
    14941 atagatcaat tttaaattat actcactcag catttctttc aactttaaat acatacaaac
    15001 catcactcca actattcatt ttcctctaaa gctttagcga ttgcaatcgc tttacgcatt
    15061 gtctccttag atatttcttt tccgtcaaaa gaaaaaacag tatcgtcttc tgataaatcc
    15121 acatgtttag gggcctcttt ttcttcgcgc cccagaagat agtctacaga gacatcgaaa
    15181 tagtcagcaa tttcttgcaa acgttctgta gaggggtttg agttcttaag tctatataag
    15241 acgtttttac catagcctag gtcttcttca actttattta atgattttcc ctgttttttc
    15301 gctaattctt ttattctctc aaacgttatc atatcaatat tcctttcgtt caagaaaaaa
    15361 tatttaactt tatttgttaa aatatgttga ctattttaac aaaagatgtt aatatcattc
    15421 ttgtaaacaa gtttaacaac taaaaagaca acaaaaacac ttttgattat taaacgccaa
    15481 ccgccaagaa agcttttaaa atcaatgttt atatgtctta tttaactatg ttctgatttt
    15541 aacactgtat gttaatttag tcaacgcagt tttttaaaaa gttgttaaat ttgtttacga
    15601 atataaaaga aaggagagaa atagatggaa aataaaaaaa ctggattaat aactgtagaa
    15661 ataatcggaa ttgatgatgc aacaaaaaaa gctgaaagat atattgagtt attaaaagaa
    15721 gccaaaacgt tggcagacga attggcttca aaggaatttg aaattgagat taagcaggac
    15781 taaaccttcc ctttgaaatc aatttcagct ccgcaatatt tacacttgtt ttttccacta
    15841 gatattttaa tttttttacc acaggaagga caagtataat cgacgccctt ttttaaaatc
    15901 ttgtttgctt cggattttat gattttttca aggtcgccac tgattttaac actggttttt
    15961 ctactcatag atccacctca ctttctacag tgagtatacc agagaaggag gtaacaacat
    16021 gaaaattagc attgaagcaa agccacaaga aatagcagaa ttgctccaag ctatcggaag
    16081 tagcaaggag cacactaaac gcaaacatcc agaatcgaaa atagaatatg atccgcagac
    16141 gggtgaagga aagcttattc ctcaaaataa ataataacct tcttgcttcg taccggtatt
    16201 gtctgattga atttacggtt cgaatagata gttaaaaact cactatcacg agcaacgcat
    16261 attacagtat catcttcgaa ttcttgaaga atcatatcgt ggttgaaagt aaataatgta
    16321 cgagttttat ctggcgcctc aattttgaat tcatttacga actctatggg caattcagac
    16381 tggaaatcca atttatagtc tttcaaagtt gccacctcct tatcaattat ttcagcctgt
    16441 cacactgata aggaaattat accaaagaaa ggaatgaaaa aatgaacaca ccacaaattt
    16501 tcaatttcga acaaaacgaa gttcggacgt ttctagaaaa tgacattccg tatttcgtag
    16561 caaatgatgt cgctaaaaca ttaggataca aaaacccgag cgatgctact aataaacatt
    16621 gtaaaaaagc cgtaaaaaca tggggtagcg attcgctagg tcgtcgccaa tctttcaaag
    16681 ttattccaga atcagatgtt taccgcttga ttatcaaatc gaacttacca agcgctgaaa
    16741 aatttgaggc ttgggtaatg gaagaagtcc ttccaacaat cagaaaaaca ggtagctatt
    16801 caaatgtacc tcaaagtttt gcacaagcat tgcgtttagc agcagattta gaagaaaaga
    16861 accaattact cgaacaacaa attgccgagt acgaaccaaa gattagctac ttagatacga
    16921 ttctttcatc gacagatacg gtagcgactt ctcaaattgc agctgattac ggaatgtcgg
    16981 caattgctct aaacaaattg cttaacgagt taggtgttca acataaagtt agcggacaat
    17041 ggatacttta ccgaaaacat atgaaccaag gatacacaaa atcgcacaca agtgagatac
    17101 cgaaagccga tggcggcact aaagttgtaa tgaataccaa atggacacag aaagggcgag
    17161 tgtttattta caacttatta atcgcagagg gctattaccc tcaaatggat ttagaggaaa
    17221 ttggttagaa aggagtttta gtatgactga cattgcagaa atcactcaac gagatagaga
    17281 aaaaatcaaa gaatatgtcg aaagttcgaa gttcttaact tacaccatgc ttgctgaaag
    17341 atttggaatt agtaaaagct atttatcttt aattttaaac ggtaaaaaga cttctgcaga
    17401 agcaaacaga attatagatt cgattatcac tatgtacgaa ttgtagagga ggaaaacgaa
    17461 atgaaaaaac caacgctttc ggagttgata gaagctactg agaaggcagc aaacccagac
    17521 gattggtatc gtcaaagttt gatcttggag aagttccacg gcatgtcaaa aactacttta
    17581 gttgaatact gcaaggaaat ggaaacaatt cctgaatttt cagaaggaat tgttcgtcca
    17641 ggacattcaa ccacatttat tcattaccat acttttattt ggtttttaaa atggaaagac
    17701 gcaaataaat atcgtgtaaa aatattgtct ccttcagatg ttttgaagga agcaagttga
    17761 ttattttcag agtaaaaagt aaacaaaaat attaggagga aaatttgatg aagattacag
    17821 taccagatga attgatagca gatgagttga cagaacaaat agtaagaaag gttttagatg
    17881 cacttgatga acgactgaag gtaatgaaca agtcagtgga gcttcctcca tatccaaaca
    17941 aatcagaggt aaaaaaagtt ttaggcattg gtgatgacaa attaacacat tggataaact
    18001 taggcttaaa aacacagcag tggagcaagt tagacatcag aattgaacga tcagaactcc
    18061 aaagattttt gaaagaaaac tttgagttct aaaggcaaag gagaatgatt ttatgtccta
    18121 cacattgcaa caagaacatc aaattctcgg tttgattaaa caacgcagga aacaattaca
    18181 agatgaccgt gcagcgctta gaaaagccga tgagctatca gatagacaag ctgaactaat
    18241 tgcttctgaa cttgaggatt tgagaatgct agaaataaaa aatagggaga ttagattatg
    18301 aagaagacag acacactttt tataggattc attttggggt tattagtgat tgtagcgcac
    18361 caaagtatta tcggaggaag cttgttcgca gcattgatgg ttttaatcaa tctgcttgac
    18421 tcaaaagaaa ggagcaacta tggcacgaga agaagcgcta aaaatcggta aagtgattgc
    18481 tgataattgg tgggcaaata gccgttctat tattttaagc aagcaacata tcgaaaagaa
    18541 aaaagcatgg caacaaataa aaaagtgact ccgccgacca aagcaatgag tcactcaaaa
    18601 aatcataact aaggagattt taacatatgg aaaatgaact ttccactcta gatcaatatt
    18661 tggccgatcc tgattggggc aaatcgaatt tacaactggt tgctaacaag tacgaaaaat
    18721 caattgatga agcaattgtt gcattgactg atgcagcttc cataaccgct gatgacagta
    18781 aatggaccaa gagagacttg ggcattctaa aacgaggcgt taattggctt gaagatcagt
    18841 acagagaaga aacaaaagag aagtgatatg agtgtttaaa ccactaatag attcatactc
    18901 ggcggtacta aagaaattta aaggtaacga cattggtgca acaatcaacg aagaagtaaa
    18961 tatcgaacgg ctgaaaacga tgtatgacgg atatgatggc gatcgagtca ttgaaattcg
    19021 ctttattgat cctagacgtt tcactgtaca gcaacgaaac ttcatctatg cgctgatagg
    19081 cgatattttc atcgatacag gcatgccaac ggacttctgg aaggaattct tctacttccg
    19141 tttcgaaggt gtcacagggc gcaaaataag cctcaaagat gaatcgagca caaccgtaag
    19201 tgatgccaat atcttagcga atatcatcct agatttcatc tttgagcatg atattccgtt
    19261 taaaaatgga tatgaaattt tgccccaaaa cgaacagtat ttcttttaca aatgcctcac
    19321 gaacagggtg tgctgtagtt gcggaaagaa aaatgctgat atacatcacg tagactctgt
    19381 cggcatggga aataaccgaa aaaaaataaa caattctggt aggcgcttta tggctctgtg
    19441 cagagaatgc catacgaaaa ttcatgtcga aggttttact acatttacaa ctaaaagaaa
    19501 gcttacggca gttgttctca aagacagtga tttaaaaaga ttggggttga atatcattga
    19561 atgaattatg gatggatatc gaaggatacg agggagtata tcaagttagt agcttaggaa
    19621 gagttaaatc taatcgccct aactatgtaa ttaataaggg atacgttaac aaagaaggat
    19681 ttattatgaa accatctgac aatgggaaag ggtatcaaat tatcttctta agcggcaaag
    19741 gttttagaga tagaaggtat gtccatcggc tagtagcttt tcacttttta aaagaagcgt
    19801 atttcgaagg tgctgaagtc aatcataaga acggagataa atctaacaat actgttgaaa
    19861 acctagaatg gctcagttct gatgataata aaaagcatgc tagaaaaaat ggattaacta
    19921 acttgaaagg accatcaaaa ctaactgatt tgcaagcttt agctatcaag cgtttatata
    19981 caaacaaatt gatgagctcc ggagaaataa tgaaactttt taatgtcagc aggcataccg
    20041 tgctgaatat agcttcaggg aagacattta gtttcttgga agattaagag aaacacaaaa
    20101 taggtgtgac taatttcaaa aataagtatc aaatcaaagg gattaagtta aaccaggaaa
    20161 caattaagaa acttagaata ggaggataaa aaatattggc tgacaacaaa cgatactact
    20221 atttaaaact aaaagagaac ttcttcgata gcgacgagat ggttctttta gaaagtatgc
    20281 cagatggata catttattct aatattcttc tcaaacttta tttaagaagt ctgaaacatg
    20341 aaggcaaact aatgtttaat gacaggattc cattcaattc tacaatgctt gcgactatta
    20401 caagacactc tgtgggagtt gtagaaaaag cagtacaaat atttcgtgat ttacaactta
    20461 ttgaggtatt agataacgga gcaatttata tgtctgatat acaaagtttt attgggaaat
    20521 cttcaactga agctgatagg aagagaaaat acagaaaaga aattgaggaa gcaaaacaga
    20581 atttaataac aagtggacaa atgtcggaca aatgtccgga caaaactaca ccagagttag
    20641 agatagagtt agagaaagat atagagttag agaaagatat agagaatgta acgcctccga
    20701 aaaaatcgaa ggctaagccc atccgtcata aatacggaga gtataaaaat gttcttttgt
    20761 cagatgagca gatggagaaa ctcaaaacag aattccctaa tgactaccaa gagcgaatag
    20821 aacggctatc tgagtattgt gaatcatcag gtaagactta taaaaactat ttggcaacta
    20881 ttcgaagttg ggcaaggaaa gaaaaaagtg agcctaagaa tgcaagtggt gcatacaaac
    20941 gcacaggacg acgagagaag cttccagaat gggcaatcga ccaagaagcc tatcaaaaga
    21001 aaaaagcgct agaacgagct aatagacaat caaaagcacc attctaagag gtggaaaatt
    21061 gaaaatcgat tatctagaac tgatcaatga aatagcaagt tacaaaactg gtgaggaaat
    21121 agagattctg agagacgttt atgaacaact tgatgaagct ggaatcgaac gaattaagaa
    21181 tgatcgttca agttggagta aactcagata ctatttcgca ctttatatcg atgcaacaca
    21241 attaagaaat ttagcttata caaaattact atttgctgat tgcgttaaag gattgcaaaa
    21301 acatcttagt gaacttgagc aggtgtaatc agatggatct aaaaacattt acagcacaga
    21361 tcgaactaat gcatcaagaa gctttaagac aaagcgcctc gtacgaagac aagtggctca
    21421 acacgttcca tggtggacgt gagagcgcac ttgatcaagt gctcaaatta ttgaaaggag
    21481 aatgtcggga tgaataagaa agcggcaatg cagcgaatta tcgaattgac ttattcagaa
    21541 gattggcaaa atgacaaaga agctgcttca gaagtgatga gacttggaag agcgatgtgg
    21601 gcagacaaga gcaacaagcc aagaccgcga aaaatcgcaa tttggcacgg tgacaaactt
    21661 ctagtgacag ggacagctga acagttagca agtctcacag gcttgcacga gaaaatcgtg
    21721 agaaaaagag ctaggtgtgg atacacagac gttaagaaga gaacgtttag atacgtggag
    21781 ggatcgtcat gacaacagaa gaagtgattc aaatgcgtat tcgaaacatt cagcgtgaaa
    21841 ttgacgatct agaacgaaca aaggcagtga tggtcaatga aacggctaga aaggcaatcg
    21901 atttgcacat agagaactta agaagggaaa ttcggagatt ggaggaatga gcgtggataa
    21961 gaaagcagca atgaaacgaa tcatcgaact gacacattct gagaattggc aagaagacaa
    22021 agaaatagtt gcagaagtcc aaaagctcgg taaatcaatg tggactgaaa aacccaaacg
    22081 gaaaacgccg agaaagattg caatttggca tggtgatcga attctagtga caggtactgc
    22141 tgaacagtta tctgaaatta ctggtctgag caaaaacatt atttgggata gagctaggag
    22201 cttatggatt gattcaaaag gacgacagtt taggtatgtg gaggagaaaa aatgctagat
    22261 atgaaaatcg aagattatcg aattaccagt gattctagaa atattgtctt atcgaaggta
    22321 agacgagatg aggaaggaaa cattcgctac accgaagcaa aagaagaatc acgagcagat
    22381 attggatact tccaaactgt ctcatcgtgt ttaaaggcga tacaacgcga ttacgtgtta
    22441 agtgaagaaa gaacgataaa aagtattatc gagtacaaaa aagcgttaga aaacatcact
    22501 aggcagtttg aacaggcatg tgagatcgag gaggagaagt aatggacgaa ctaatcacaa
    22561 aagtagagca gtgggcaaaa gataagagat tggatcaagc agatccaaaa gcacagtttt
    22621 tgaaagtagc tgaggaattc ggagaaattg cttcggcaat ggcaagaagt aatgatgagc
    22681 tatttaaaga tagcgtagga gacgtaatcg tcacactgat tatcctttcc atgcaaaaag
    22741 ggacaaacgt acaagagtgt ttagaaatgg catacaacga aatcaaagga cgcacaggga
    22801 aaatggtaga tggtgtattc gtgaagtcga gtgatttgga gaacagcgaa tgatgatgcc
    22861 aaaagaaatc tattcagatg cattaagagg tgctagaaat caattgaaaa tggcgaaaag
    22921 aacatacgaa attcggccca caatcgaaaa tgaacgcaga gtaaaagcaa ttagacgcag
    22981 atgttcaatt tacggcgagt tacagaagga ggacagcaaa tgataccgag atttcgagcg
    23041 tgggataaaa aaacagaaac tatacaagag atagaatcaa tatctttcaa agaaaaaaag
    23101 ctagtgattg atcaaaaatc tgtcacttgg ttcaactcgg attatattag aaactctgac
    23161 gaagttgaac tcatgcaatc cacaggactg aaagataaga atggtgtgga gatatttgaa
    23221 ggggatttgg tagagcatga cgataattta aatggtgatt gggaaacatt tgaagcttgt
    23281 gaagttgtat atgacaaaga ttacgctcaa ttttgtttta aatgggatgc cggtaatttc
    23341 ctgacggatt atcgcaattt aaatgttatc ggaaatatat acgagaatag cgagttattg
    23401 gaggaacagc gatgaataaa caggaagcaa tcaaaaagtt agaaagtatt aaagcgatag
    23461 gaaatgatgc aatagctgct tgctataacg agagtataaa ttcaggtatt acgttaatga
    23521 aaaaaataga cgaaccgcag aaaccagtta ttccacaact cgtggccggt tggcttgaga
    23581 aatctacgga cccttttaca aaagctgaaa aaatagcgta tttaatcaaa tctaaagatg
    23641 gtgattcata ttatttctgt gattggtttg tacgagatgg catagtgacg caagagcaag
    23701 gagaagaatt actcgcttgg gcaacaagac aatcatatga aacactattg agcctataca
    23761 acggctacga ggttgagaaa gagccgttat gggcaataaa gaatgccgat ggaaactatc
    23821 ttactaaatg tgctttatgg ggaaaagatg gagtaaatta tagttttgaa tgcaatccat
    23881 ctcatcgatt gcttttcact gataaagcaa cagcggatgc tgcagcattg ttggtgaatg
    23941 gaacagtgga agaggtggta gaaagatgaa actaaaagac ggattttacg ctagcagtca
    24001 cggtatcggc ggtttaatgc tagatatgcc gacaaagaac cctaaaacac gcaagaaatc
    24061 aaaattcaaa gtcggtgaca tggtccgctg tgaagcagaa gagttcgttt atccgttcag
    24121 aggatacgtt aaaaagatac tgtcaaactc agcaatcatt cgtattgaaa atacaatgaa
    24181 gtgtgatcgt tcgactgcaa aacacaagca ttatttagct gtagcgagat tagttgacat
    24241 ggaagtaatc aagagcaaat aaaaaaagcc ggatcgctcc gactgattca ataaatccaa
    24301 cacatttatt atatcacata aaggagcggt ttgacttgat gcaattgtta cgagaggtag
    24361 atttcaaaca gacaagatgt aatgcgagag atgtgctgaa gaactttcgg cgtttggagc
    24421 ggatggcagg tcgctctttg atagatatta agtcgccgat tataacggat atgccgaagg
    24481 caccgaagca tggcaataag gcagaagacg cgattattca gatgatggat atagaaacgg
    24541 agagagatgc gattctagcg gctttgatgg ctcttagtct gattagtcgt cagatactct
    24601 actacagctt ctgtgtgcca gatagcttct caaactacag aattagccgt gaagtgggtt
    24661 attcagaaag aagtatacaa cggatgaagt cggaagctct aatagagttt gcagaagcat
    24721 ataaacacgg aaaaataatt gcttataaat aatttggcgg ttttttggcg gaatgatggc
    24781 ggtttttaga catttaccag tgttattatg gtagtgtcga aagattagga aacaggatcg
    24841 acaaaataaa cgaagggagg caatctccct catcgtttta aacttcttct tagatagaca
    24901 gcaactaatt atgaagaaaa ggatgtgaat tcaactcctc ctaaattctt catcggttgc
    24961 tgtttatttt gattagacag cagcactcac aaaactaaac atgttcttgt cgtctttcaa
    25021 ctgctgctgt ctattaattt atgtattgga gggaagaaaa atgaaattat cagtagaagg
    25081 cactccagaa gaaatacaag aattgctcca agctattggt agtagcaagg agcaaaaggt
    25141 aagtgtttct aattcagata ttgacggtat ttgcaattgt ttaaacagag aaaaaatatc
    25201 taatccttac taagagaaaa tatgttcgtt aatgaatttc caattttcct ctgtagctct
    25261 accttgataa tttttttgca gttcacagat gaataaggaa tcgttattat caagtactgt
    25321 atttaatttt tcacacattt gatttggatt caaattagtt ttaactaacc aaaaagattt
    25381 ttgtagcttt atatatgccc caaattcttt tattatttca aatactttat catacttttg
    25441 ccctgggtta ttaagatcat aactaatcat gtagggttta tacatgttgt cttgcacatc
    25501 cttgttttat atttcagcgg accactcgct gataaataaa attatacgct tagtatttat
    25561 tttcacaata ttaatttatc gtaataactt ttgagtaaat agaacaaaaa acctgcacta
    25621 gtttccgcta gtacaggcag tgactatatc ggttgataat ctagcatata ttaaaaataa
    25681 ttgcaagaaa agaaatttat agtggtttat accaaattat caaagcaatg ttattttgtt
    25741 gctgtctatt gttttttaat tattcacacg ataactaaag gtgggtgaag agaaatgatt
    25801 ccattaataa tttcaatttt tgcgctctgt cttaatgtct atatgattgg atttaaaaat
    25861 gggcaaaata aaaaatagta gcagccaaga ataattttat agtgtcactg tggcggaaag
    25921 ggtagacgct aagcatgtgt gctaggtcaa tgcttcggca accatgcaag gttcgattcc
    25981 ttgccagcga cattaaatgc ctatgacggt tacgactacc gaaaaaagat cgttaagaag
    26041 ctatacggtg ctacgtacgg caatgtagta agtgtgctat ctgtacacca ccaagcttcg
    26101 gtcactgtgg cggaagtaga agacgcagcg gtaaatggcg agtagcctcg tgagagcctg
    26161 gtaagttctc gtgagtggtg caatcccact ccagcgactt taagcaaccg aggcatcggc
    26221 ggtttaaaaa tataggggtg cgcaatttcg tacgcgtttt gtgcatcgtg caagttacta
    26281 ttacatatta gatcactctt tgagtggtct ttttattttt gcacaaagga ggaaacaaca
    26341 atgtatagac cacaatactt agaacagaag tatgaagtaa tcactgttca taaaggtaat
    26401 ggcgaaaaag tatatgagta tagaagacca ataaagagcg atacatataa acgaaaggaa
    26461 aacaatgaag ttattccatt gtatggcaaa agaatagcta agcattaaat aagattgcga
    26521 aaggagacgg aacatgaccg aggaattcta tagatggcta ttacagttga caagagaaga
    26581 tcgtttggtt aagttctatc agtctcctaa atggcgcagg cttagagaga aagcgatgaa
    26641 acgagatcac tatgaatgcc aagagtgtag aagactaggt aagtatcata gagtagagaa
    26701 cgttcatcat ataaaggaag tcaaggatag acctgactta gctttagatt tagataatct
    26761 tatttgttta tgtgttgaac atcataatga agttcatggc agatatctta cagcattaga
    26821 taaacaagag aagaagatag aaagctttgc taacttcgat gcaagtgaaa ggtggtaagt
    26881 gcatgatcat caatgataat ggcagagagt atgatacaga aaagattgaa gagtattcat
    26941 cttatactca gggattaatt aaacgtttga tatacgttcg ctatgtaggt attagggatc
    27001 tgttatcaga taactgttgt agtaaataca aagtgaatca agtaagagaa gcgttgaata
    27061 aagataataa cgtcgaaaga ataaaaaatg tttttggata tagtattgaa gagattaatt
    27121 attacattga cttcgctgaa gctttcattc cgatggtgag ataacccccc cttaaaataa
    27181 atcgcaaatt ttttgggggt gatgaaacgg agggggctgt caggaaaaga gattttttcg
    27241 aactttatca tgaaaggagg gctaaaatgt ttaaaaacga attgtctcaa aatcgctaca
    27301 gagaaaaatt acgccgctct ttaataagcc aattggaaag tcagaaaaca aatattgagc
    27361 cattcttaga taatgttgat cgttatatca gtttatggga aacggcgata tcactggaag
    27421 aagatatatc cgagaacggc attagactgg agaatggtaa aaagaatgaa tcagtagcgt
    27481 tgcttgtttc tgtcaacaaa caaatgggat tgatgttgga taaacttgcc attactcctg
    27541 aattggtagg tgaagcaaat gaatcaattc ctgagttata agcatattga aaattggttc
    27601 aaagctatag aagaaggcac tatcaaggta tgcaaagagc aattattgct aaaaaattat
    27661 ctagaagaaa gagtctttac tagagaagat atttacttcg ataagcagat ggtagaggat
    27721 tcaatcaata taccagcaca atactttcca ttcgaattaa ttccgtggga aaaatttcta
    27781 caatgtttta tttatggtgt tcgatggaaa aaagataaaa cactagtgtt caatagatat
    27841 ctttcattaa tgggacgtgg taatggtaaa actggttttg cttcttggaa caacttcttt
    27901 ctactaaccg ctaaacacgg tattaaaaat tatgatattg atatctatgc caataatgaa
    27961 agccaagcaa agactagttt tgatgatgta tttaaagtaa ttaaagatca tcctgattta
    28021 gataaaaaag tatttaaagc tacgaaggaa gttattcaaa atatcgctac aaacagcaaa
    28081 cttcgttata acacggcaaa tgctagaaca aaagatggga agcgaccagg tgcaaaccgc
    28141 tttgatgaaa ttcacgaaaa tgaagattat tcaatgataa atgtggctac ttctggtggt
    28201 ggtaaaattc gagattatag agaattttat gatacaacta atggtcatgt tcgtggtggt
    28261 ccgcttgatg acattataga agaatcaaaa atgattcttt ctggagaact tggaattgac
    28321 aaggatggag cagaattttc tagtttgttt ccatttattt gtcgcttgga taacgataat
    28381 gaagttgatg atcccgacat gtgggaaaaa gcttgtccaa ctattaatta caatgcagat
    28441 ttaaaacgga aaatgtttca agaatactct caaatgcaac gtaatgctgg tttaagactt
    28501 acgttcatga ccaaacgaat gaacagacct atggaagata cacgatttgc tgttgcttca
    28561 tatgatgatg ttctgcatac gaaagaaaaa gaatttcctg aaaaaatgga tgaagtgata
    28621 ggaacagtcg attttgctga tagacgagat tttgccagcg ttgggttgct aggaaaatac
    28681 gataaagatg tttattttac acaacatact tttatccacg aatcagccct tcgattacaa
    28741 aacatcaaac gagaggttat agatatttct atagatcaag gaaaatcaca gatcgttcat
    28801 ggaaaaaata tagaagctga ttatattgta ggttggtttc ttgaaatgag taataaatat
    28861 tatattaaaa aaatcgctat ggatatgtac cgtgcaaaaa tattgaagcc cgctttagaa
    28921 gaagcaggtt ttactgtgga aattgttcga agcggatctg ttacacatgg tatgttaaaa
    28981 gatctggttg atgacctttt tattaatcaa cgtttatttt ttggtgacga tgcgattatg
    29041 cgttggtatt gcatgaatgt atatgaagag catatttcta atggaaatat acgctatgaa
    29101 aaaatagaac ctgaaactag aaaaacggat ggcttttttt cattccttca tggtttgaat
    29161 tttttagatg atatttatga ttctgctcct gtaacagtca caaatagctc agtagaaaat
    29221 acaggaactg gatttactcc tctagtattc taacttgaaa ggaggtgaga aagtggggat
    29281 ttttcaaaag gcggtaggat acttcacaaa aaaagcaacg gttcctttag aagaatactt
    29341 ttgtaaattg caagttgatt ttgtgtatcg aaaatttgcg attgaaactt gtattgattt
    29401 gattgcaaat gcgatgagta aagcggaatt caagtcatat gaagatggaa aaaataaaaa
    29461 gaatgatctt tactataggc tgaatgtagc tcctaataag aaaaataatg caacagaatt
    29521 tagaaaaaaa ctgatcagga gattaatatt ctacaatgaa gtattgatcg tttctccgtc
    29581 taataattct agcgaaatat ttattgcgga tagttgggat gtcacagaat atgcattgaa
    29641 agatgatgtg ttttctcaag tgcaaattaa caacatagtc cttgatagag aatttctaga
    29701 aagtgatgtt atctatataa aatacgcaga tcaacaaatt aggcaactag tcgatgcgta
    29761 ttatcaagcg tatgggaaac tcatttctag tgccatgaat gtttacaagc gctctaacgc
    29821 tcgtagatac gtactgaaag ggaatttatt ccgaccgcaa gacaatacaa cacaagatca
    29881 aatcaataaa atgatgacat cacaatttaa ggcttttatg gaagctgata atgcaggtgc
    29941 ggtatttcaa ttacaaaatg agtacacatt agaagatttc agcggaaact tccaaagcaa
    30001 ttcaagagat ataaaaaact taatagacga catctttgag atgacagcag cagcgtttca
    30061 cgttccgaaa aacctactaa agggagacat gagtgggtta tcggatcaag tggacgcttt
    30121 tttaatgttc gaaatcatac cgattgctga acttattcag gatgcgttta acgctagtct
    30181 ctatgaagta gaagaatact tgtcagggaa ttttgtacgt gtggatacaa ctatgatcaa
    30241 gattactagc ttcaaagatt tggttgacgc tattgatgta ggcattagaa atggagtatt
    30301 tacaatcaac gaaggaagag aacgcgttgg aaatgatcgc tctgataagg cgatggcaga
    30361 tgaaatattt ataactaaaa acaatcaaca agtatcgaaa ggaggtgagg cgaatgacga
    30421 caatgaaaac atttctagca gtaaagaatg aaggcgcagt accgcaaatt tttattcagg
    30481 gatttattgg ttctagttgg ttctttgaag ggaatactga caagggaatc aaaaatattt
    30541 tggatagtct aggtgatcaa gaagaaattg aagtagtaat taattcaaac ggtggagacg
    30601 tatttcaagg gattgctatt gggaacttac ttaagtcaaa taaagcaaaa gttaacgttg
    30661 tgattaacgg cttagccgct agtgctgctt caattatcgc aatggctggc gatactataa
    30721 aaatctacaa caatgcacaa ttgatgattc accgcgcttc cacatacgga gaaggaaatg
    30781 tcgatgactt ccgtacgatt gctgaccaac tggaatcaat tgataaatcg gtaaaggctt
    30841 catataaaac acgattcaat ggcacagatg aagcattgca agaacttctt gaaaaagaat
    30901 cgtttatgga tgcagaaaca gctttgagtt atggattggt cgatgaaatt atcgatgcag
    30961 aaaatagctc aggtactgaa gctaaaaaag aacaaagcgt tgaagaaatt ttgaatgacg
    31021 ttaaagaaaa aagagcagaa aaaattgctg catttacagc agcattaaat aaaacatttg
    31081 gacaaggaga tgtaaaataa tgacagttaa aaatttaaaa ggtgtaacag ctgcaagcga
    31141 ccaattgatg aaagctttta aagatggtaa cgaagaatct tttagcgcag ctatggtaag
    31201 cttatctaag gaaattcagg ataaaatttt agaagaagca acagcaaaaa atcaagatca
    31261 attagtatta atgaaccgtg gtcagcgtgt attaactaca caagaaacaa aattctataa
    31321 cgaagtagtg aaaaacgaag gttttgcagg ggtcgaagaa ttagtgccag ctactgtatt
    31381 tgaacgtgta tttgaagatt tagaacaatc tcatccacta ttgcaaaaaa ttacttttgt
    31441 taacacaact ggtgtaacag aatggattgt gtcacgtgga gtcaatccag catggtgggg
    31501 taaactttgc gaagctgtta aaaaagtttt agataatggc tttgatgtaa ttaacatgaa
    31561 gcagttcaag ctatcaggtt atattcctgt atgtaaggca atgcttgatt taggtccagt
    31621 atggttagat cgttatgtcc gtactgtttt agtagaatca ttgagaattg cattagaaca
    31681 agcaattgtt gatggtactg gtaaagatat gccagtcgga atgatgcgtg acatgagcaa
    31741 acaaactagc ggagaatatg ctgaaaaaaa agcagaacct attacagctt tagatgctgt
    31801 aactatgggc ggtttgatgg cgcgactatc aaaattcaat atcgaaggtg tgaatgatcc
    31861 gatttatcgt aatgtgaatc cttctgatgt ggtcctaatt gtgaatccaa ctgattactg
    31921 gtctaaagta ttcccagcta agactgtact aactgctaat ggagaatacg tacaagtatt
    31981 gccagtacca gtttcagatt tgcagtcaac ggctgtgcca gaaggaaaag cagttattgg
    32041 ggtagcctca gattacttca tgggtgtagg atctacacta aaaattgaag cttcagatga
    32101 ataccatttt gttgaagacg aacgcattta tctagctaaa caatatgcaa acggtcaacc
    32161 taaacgtaac gatagtttca ttgtattaga tattagcgct ttgggaacta ctactacaac
    32221 tacaaaacca acaaccacaa caactacaac acaagcgtag gtgatcagaa tgaagtatat
    32281 tctttgtcag ccggcaatca atcggtttaa atgggagctt gaagtttgtt taactaatct
    32341 gaagaaacta ggaatcaaag atatcgtatt gcttttcagc agacacgatg atcagattcc
    32401 tatttttttt gagaaggaat atggtgttga agttcatgtg tacgatgatc tgcgggacga
    32461 caaagagtat attccttcga ttaaaccata tttatggtgg aaatatttag aagaagatca
    32521 ttcgcgtgag gacgaccgat atttctatat cgattcggat gtcattttca ataaaagaat
    32581 taatttgcgc aaattgcctt ctaaagatga tgtttggtat tgtagcgact gctgtagtta
    32641 tctaagtctt gattatatta gaagctgtga aaacggagaa aatattctaa aagatatggc
    32701 aaacattgta aatgttacag tagaatcttt ggaaactata aacactaatt caggaggcgc
    32761 acagtgggtt attaaccgtc ctaaagcgaa ttattggaaa aaggtttatc tggattctaa
    32821 tcggctatat cgctacctta gagggcaaaa aacaaatata caaatct
//
LOCUS       DACDAF010000021        31358 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.021, whole genome shotgun sequence.
ACCESSION   DACDAF010000021 DACDAF010000000
VERSION     DACDAF010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31358)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31358)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31358
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.021"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            59..3337
                     /locus_tag="IVZ69_000962"
     CDS             59..3337
                     /locus_tag="IVZ69_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HAP8183067.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(3878..5785)
                     /locus_tag="IVZ69_000963"
     CDS             complement(3878..5785)
                     /locus_tag="IVZ69_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HAP8183068.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            5915..6790
                     /locus_tag="IVZ69_000964"
     CDS             5915..6790
                     /locus_tag="IVZ69_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HAP8183069.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            6870..7844
                     /locus_tag="IVZ69_000965"
     CDS             6870..7844
                     /locus_tag="IVZ69_000965"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP8183070.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            8033..9169
                     /locus_tag="IVZ69_000966"
     CDS             8033..9169
                     /locus_tag="IVZ69_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP8183071.1"
                     /translation="MKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGRHAH
                     EKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIEHPA
                     VLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLMPIK
                     EIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKRDGV
                     NIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLILDTL
                     EANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNIEPS
                     HVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            9306..9650
                     /locus_tag="IVZ69_000967"
     CDS             9306..9650
                     /locus_tag="IVZ69_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HAP8183072.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            9921..11207
                     /gene="efmA"
                     /locus_tag="IVZ69_000968"
     CDS             9921..11207
                     /gene="efmA"
                     /locus_tag="IVZ69_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HAP8183073.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(11345..11944)
                     /locus_tag="IVZ69_000969"
     CDS             complement(11345..11944)
                     /locus_tag="IVZ69_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphatase"
                     /protein_id="HAP8183074.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            12348..13469
                     /gene="mnmA"
                     /locus_tag="IVZ69_000970"
     CDS             12348..13469
                     /gene="mnmA"
                     /locus_tag="IVZ69_000970"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HAP8183075.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            13715..15136
                     /gene="arcD"
                     /locus_tag="IVZ69_000971"
     CDS             13715..15136
                     /gene="arcD"
                     /locus_tag="IVZ69_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HAP8183076.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            15150..16268
                     /locus_tag="IVZ69_000972"
     CDS             15150..16268
                     /locus_tag="IVZ69_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HAP8183077.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(16328..17620)
                     /locus_tag="IVZ69_000973"
     CDS             complement(16328..17620)
                     /locus_tag="IVZ69_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP8183078.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            17770..18330
                     /locus_tag="IVZ69_000974"
     CDS             17770..18330
                     /locus_tag="IVZ69_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP8183079.1"
                     /translation="MKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDIKAPSLY
                     NHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSNQAVYEL
                     LISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYLSLRFLG
                     YFTKEPTIDPEDSYFWMINNFIATLP"
     gene            18459..18836
                     /locus_tag="IVZ69_000975"
     CDS             18459..18836
                     /locus_tag="IVZ69_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HAP8183080.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            18769..20841
                     /locus_tag="IVZ69_000976"
     CDS             18769..20841
                     /locus_tag="IVZ69_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP8183081.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(21052..21999)
                     /locus_tag="IVZ69_000977"
     CDS             complement(21052..21999)
                     /locus_tag="IVZ69_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP8183082.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            22245..22709
                     /locus_tag="IVZ69_000978"
     CDS             22245..22709
                     /locus_tag="IVZ69_000978"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HAP8183083.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            complement(22771..23814)
                     /locus_tag="IVZ69_000979"
     CDS             complement(22771..23814)
                     /locus_tag="IVZ69_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HAP8183084.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(24191..25156)
                     /locus_tag="IVZ69_000980"
     CDS             complement(24191..25156)
                     /locus_tag="IVZ69_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HAP8183085.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            25390..26235
                     /locus_tag="IVZ69_000981"
     CDS             25390..26235
                     /locus_tag="IVZ69_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP8183086.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            26426..27613
                     /locus_tag="IVZ69_000982"
     CDS             26426..27613
                     /locus_tag="IVZ69_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP8183087.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            27619..27975
                     /locus_tag="IVZ69_000983"
     CDS             27619..27975
                     /locus_tag="IVZ69_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HAP8183088.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            27977..28315
                     /locus_tag="IVZ69_000984"
     CDS             27977..28315
                     /locus_tag="IVZ69_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HAP8183089.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            28710..29744
                     /locus_tag="IVZ69_000985"
     CDS             28710..29744
                     /locus_tag="IVZ69_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8183090.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     gene            29737..30423
                     /locus_tag="IVZ69_000986"
     CDS             29737..30423
                     /locus_tag="IVZ69_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183091.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            30447..31295
                     /locus_tag="IVZ69_000987"
     CDS             30447..31295
                     /locus_tag="IVZ69_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP8183092.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
BASE COUNT        10230 a         5720 c         6663 g         8745 t
ORIGIN      
        1 aataaattag gtaatacttt aagtaaacgc tttctaattt gttacgggag gaatacactt
       61 gttaaaaaaa cgtataaaat acagtgcgct aatgatgaat ctccttatgc tcagtacccc
      121 ggttttaatt tctgtcgttg aagttgctgc taacgaacaa cagtctgtga acgaagaaaa
      181 tgcacacgtg aacattgaag ggatgtcaac aatggaggaa ataccaagaa ctagtgaaga
      241 tatggatacg gaagaaggaa atgatcctat gatgaaagaa tcagaaaatg aaaagacaaa
      301 aaagcaatct gaagaagcaa atgaagagtg gaaaggggtt gttttcggag aaagcacaag
      361 tgctagtagg tatgccattg aaccattaga agacggcgtg cggctctctt ccacgaataa
      421 cggcggaaaa ttccagtcaa gcggatcaga tggaatgacc tattattatc aagcaatccc
      481 caaagacatc aactttagga tgcgggcgac gatcgaaata gaatcttgga cctatacgaa
      541 tgcccaagaa ggatttgctt taatggtaag agacgcagta ccaaaaaatc atttgtttgg
      601 gcaggcattt tattcaaatt catttgccat actaggcagt cggatcgaat atgtctggga
      661 ctcggataga caagaagtgg tcaacacgag cggcagcaaa tatacgatgc gacttggatt
      721 ggggacacgg gcaatcacag gaatatcatc tgaagatccg caagctgcgc cagctcctgg
      781 gagtgtctca gtggaaacaa cacctttaga gacttcagca gggttcttgg aaaaagaaac
      841 aggttcttat aatatattcg gaaacggtca tgggaatctg tttccggcca cgaactcgat
      901 tactaaactg gacgtagaga tgaaaaaaac gaatactggt ttagaggcat attattacga
      961 tcctgaaaca ggagaagaaa tggcttctga catcatgtat gactgggaaa aattatacgc
     1021 ttcagatgaa tcggttattt atgcaggatt tgctgcagca aggaatatga cgatcaaggt
     1081 agaaggaatc gaagttgctt actcagatcc tgcgacagat cctcctgggc aagaaagacc
     1141 tactcgcttg attgatccga tttacactgt gacctctagt aatcattcag gaaaccaaga
     1201 tcatactatg tcctttagag caaatgctga cggattattg acaattaaaa ataaagcaac
     1261 aggagaggtg cttaagaacg caaaaaactt ggctatcact gcgaatcggg aatttgatta
     1321 tcagacaaaa ctgatggaag gaacgaacga atttactttc agttttacgc cagataaaaa
     1381 ctatccgcca gaagaatacg tagagatgac tagttatgaa acaaaagaga ttcttcatac
     1441 agtggactac cgtaaaccta aatattcgac agtttatgta acaccagaag ggtcagatgc
     1501 aggaaacgga agcagacaaa atccattatc tctgacacaa gcattgagat acgcatatgc
     1561 tgggcagaca atcgtcatgg cgcctggaac ttattccttc gaaagaggat tgacgattcc
     1621 aaaaggcgtt aacgggacaa gagaaaaccc gattcagttg attgcagaga aaaatccaga
     1681 aaacaagcgt cctgtacttg attttaaagg aactggaaat gggatgacac tgttcagtca
     1741 ctactggggt ttacgagggt ttgacattac aaatagtgca gctatgcaaa aaggattaca
     1801 gatttctgga aatcataatt tgatcgaaga gattcatgct tatcggaatg gaaatacagg
     1861 aatccaaatc agcggtagct caaatgatcc tttcgaagca tggcccgcgc ataacttagt
     1921 caagaactgt acatcttttg aaaatgccga tccaggattt gaagatgccg atggatttgc
     1981 ggccaaactg acaataggag aaggaaatgt atttgacggt tgtatcgcgt atcataatgc
     2041 agatgacggt tgggaccttt ttgctaaaaa tgaaacaggt tcgatcggaa aagtaatcat
     2101 caaaaactca gttgcttatc gaaacggctg ggtaccagga attgagggag aaggtaacgg
     2161 taatggattc aaaatgggcg gttcttcttt aacgggccct catgaattga tcaatagttt
     2221 gtctttcgaa aatcttgcga aaggaatcga ttccaatagc ggaacagata ttatcgtcaa
     2281 tagcagtaca agttttaata acggttcata taatgtggct ctttatacct cttcagcagg
     2341 aaacacagac taccatgctt ctggtatctt atctttccga acagagaatc ttgagatgag
     2401 agagcagatc cgcccattga atcaaaacga agatcaaatc taccactcgt tgaactacta
     2461 ttggaatgaa cgagagaaac aatcagaaaa tactcttgga cataccatat caaaagattg
     2521 gatcgagtct ctaaatacat gttcgaaaga aggtcagcag cctgttacgc gctatgaaaa
     2581 tggaagtatc catgttcatg gactgatgca gattaaaccg gggaatcgtc aaacagaaaa
     2641 ggaaagagtg gatggtcttc cattatctgt aggtgctatt tttgacggag aaacctcacc
     2701 gtcttcggaa tatccagagt atgcaatcgt acaagaacca aatcagacaa aaccaaatga
     2761 acaaaataat ccgattatta tacaagaagc aaatggtgtg gcggagaatg cagaaggaaa
     2821 tatcattgaa ctgaagcctt ttacagtttt tgtgtcaact ttcacaccaa atcaaggaac
     2881 gcctgtcttt gaagatatgc gttatttccc agaaaagatc caaatcgttg aaacacagtc
     2941 aagtgctcaa ttttctaatc ataccgctat tttttcagca ccttcaaaag gagaatatac
     3001 gctagaagtc acttatcgtt cggaaatatt tgatggggaa aaatggtctg ctcatacaga
     3061 atctgttacc cagcaaaaag cgatcactgt gcgagaaact gccgatgtgc ccccgggaaa
     3121 tgacaaacca gaaagagaaa atccaggaaa tgaatcacca aatggaaaac caaatggaaa
     3181 accttctcat ccggatagga cagcaaaaga aagtgaaaaa aatggcactc aaggactccc
     3241 aaaaacggga gaatttaata acccgttgct agcattagct ggaggaattt tgttaatcgg
     3301 tgtagttgtt tatgtcatga aacagcgaaa aaaataagtg gaatttctcc ttttatgatg
     3361 taaaacaatt gactgaggaa agtaaaaata gaaggaaatg agaccaatag atgtctcact
     3421 tccttctatc tttttataga tgaggttctc cttgctgctt ttgattggct gttcttatta
     3481 cttgatgcag gacagctttt tcacaatctc tccactaaac ggtgttcaat cagctgaccc
     3541 tcggtattag ctcaacaaac ggcaaaatat gaggaactat ttttccgttt ttttctctaa
     3601 tactcaggtc aggacgctga tttcacaacc tctcgataaa cggtgttcaa aagccagttt
     3661 ctcggtagta agtcaaattt atgcaaaaat gtggaaagcc attttcacaa aatttttctt
     3721 actacttgaa actaagcagc tttttcacaa cctctaatac atggtattcc agaagtaact
     3781 tcttcgaaaa ataagccgaa atgtcacaaa aatttgagaa gcgattttcc caaattcctt
     3841 cttatttctt gaagctgacc acttctggca caacctctta ccagattcgc actctttttt
     3901 ctggcgctag atacatagcg tcttgttccg tgataccaaa tgtttcatag aattcgtcaa
     3961 ggttttttgg ttgcacgttt gctcggagtt tagcaggggc atggacatcg atttgcagta
     4021 aaagttgttg gtattctttt tttgcttttg tacgccaaat cgttgcccaa ttgacaaaga
     4081 attcctcgat agaaagatct gattccgttt ttgctgcttc caatgcacag cttagaccgc
     4141 ctgcatcagc aatattttcc gaaacggtta attttccgtt tacttttccg tcagcaaaag
     4201 gcagaccatc gaattcttcg atcattgctt gtgctttgtt ttgaaattgt gtaagatctt
     4261 cttctgtcca ccagttgttc aagttgccat attcgtcaaa taaagcgccg ttattatcaa
     4321 atgcatggga aatctcatga gcgataacag ctccgattcc accataatta gcagagcttg
     4381 attgttctag actgtaaaat ggtgcttgaa ggatcgctgc cggaaagacg atcacattcc
     4441 gaaatggatg ataataagca ttgaccgtgt cagcactcat ttcccattct gaacgatcca
     4501 ctggtttgtt ccatttgctg aaacgatctt ttaatgtgag tttgctgaaa acaagagtat
     4561 ttgaaagcaa agtaccaccc tgatctgcag gtactgtttt gaactggtcg aataatgctg
     4621 ggatcttatc ggggtagcct acttggatac ctaagttatt taattttatg acggcttttt
     4681 cttttgttgc atccccaagc cagtcatttt cttctagacg ttttttataa acggcgatca
     4741 tttttttcac catttgttct acgtcttttt tagcagcttc gccaaaatat ttttttccgt
     4801 agtaatcgcc aactacttga tcgaattgtc cagaggcaag gtaatacgct gcttttttct
     4861 gaggcattgc ttcgtctgtt ccagacaata cgcgagaata gattccgctg acttggcgga
     4921 attcttctga tagataacca ctaagagaac gtactgtttt aatgatcatc cagcttttga
     4981 ataacggaaa atgagcttct gtcaggatgt cattcaaatg atcgaagtac actggatcag
     5041 ttacgatcac tttatctgga gttgtcccaa tcaaacccgt gacaagtttt ttcaagtcca
     5101 gtttatctgt gtatttaata aatgtatcaa aagattgcgg attatacatt ttgctgtaat
     5161 ctgcgttttc ttctgcactt tttacatgag gagcaatcaa tttatcaaat tgcactgctt
     5221 gttccgtgat tgcttctgcc tgactttttt ctttgccggc aagctctaat aactgaacag
     5281 ccatatcaaa gaaaacgcct attagttgtg caccgttggg atggtctgat gcataatacg
     5341 tcttatctgg aaggaataaa gaaggcggat aagcaaagaa ggcgttcgtt tgcgcattct
     5401 tcatatctgc atctacatcc agattaaatg gcaatggtaa tgtatccaac agccattctg
     5461 gaaattgctt attcaattcg tcgaaagact gcaatgattc aactttttcg attataggtt
     5521 gaagcggttg agcatgcaac tcatttcttc ggtcataatc gtttgccagt tgataatatg
     5581 caaggaaatg tttcattttt tctgaagaca ctttttctgg atgggcaagc agatcgtctg
     5641 tttctcccat caaaagttgg tcgatcccgt caactaaatc ttggaaaccg cctgtagctg
     5701 gtttatctgc agggattttt gctgtttttt gccattcttc attgactgct tcatagaaat
     5761 cttgtttcaa tcgttctttg ttcattcatc gatcgctcct tttttgtttc gtgtgcccat
     5821 tatcttacaa aatgaaggaa ttaacaaata gaacataaaa aattgaaaat tcgaacaatc
     5881 aaactgattt gtttttttca atccttcact tataatgaaa aaaaggaggc gatcccaact
     5941 gaatcaagta gtggataaac ctttatattt caaagtagat aaaaaaatta aaaaattagc
     6001 cagcactcag cagctgcagt caagaaaaag taaattgctt tttttagctc tggtttttga
     6061 agatcaaagt tatgtgatta tcgatcaatc aggacatccg gtagaatatt ctccagcaaa
     6121 atatacttat caagagggtc tttcttgtaa aaaatggaag ctgatcaatg aagagccaat
     6181 cgagttatct agatggatca acagaaaaga agatattccc gttttgatcg aagaaaaaag
     6241 gtcaggaaag gaactcgcaa attgctgggt gggattgcca gaagaacgtt ttttgaggta
     6301 taagaaatgg gctaccccct caggctatct ttgtggtact tacgcggcag cagttctcct
     6361 tgcctattat caagactatc gtaaggggtg gatgcttcca aatgagattc gcaagaaaaa
     6421 tacggctgat tcgttggttt tgacgaaggc attgcgtagc cagatccaac cactaggact
     6481 tcctacgatt ccttttcagg ttagtacagg gatttctagt tttttaaaga agaatggcaa
     6541 tcatgagcgt gcacgagcaa ctcttctagg ttcatggcag cgagctacaa aacgtatacg
     6601 tgaaggcaaa cctgtgatga ttggtatttt gaaagtactt ggcagtacat atggcaatca
     6661 ttgggtgaca gcgtacgctt attttgaaac tgaaacagga gaacgttatt acaaagtaca
     6721 cgacaactgg ggcgattatc ataaagtcat tcctgccagt tggagtaacg gaacagtttc
     6781 acttccttaa gaatttgctg aaattaacag aaaatcttgg aaaaatatgt taaactatcg
     6841 aagaatagag aagttttggg gaggactaca tgagtaataa gtatcaggat gacacgttga
     6901 agatttttag tttgaatggc aaccgtccat tagctgaaaa aatcgcgaaa gtgttcggaa
     6961 cagaattagg taaaagcgtc gtgaagcaat ttagtgatgg cgagatttcc atcaatatcg
     7021 aagaaagtat tcgaggggat catgtgtata tcgttcaatc aacgaatgca cctgtcaatg
     7081 attactatat ggaactactg atcatgatcg atgcaatgaa gcgagcaagt gcgaaaacga
     7141 tcaatgtcgt attgccttac tatgggtatg ctaggcaaga ccgcacggcg aaacctcatg
     7201 aaccgatcac tgcgaaattg atcgctaact tgatcgaaga agcaggggca actcgagtac
     7261 tgactttaga tctgcacacg gttcaagtac aaggattctt tgatattcct gtagataatt
     7321 tatttacgat gccgttgttt gctcattatt accgtcaatt aggtctgacg ggagatgaca
     7381 tcgtagttgt ttcgccaaaa aacagcggtg ttcagcgtgc acgtagtctt tcagaatatt
     7441 tgaacagcac attagccatc gtagatcatg cagatgatgc ttcaactgag ggtggttatg
     7501 tgatcggtga tgttcaagga aagacatgta tcatggtaga tgatatcttg aacacaggag
     7561 caacgcttgc acgagcagca aatgtattaa aagaaaacgg cgcaaaagaa gtatatgcct
     7621 gtgcgtcaca tggattattg tccgatcatg cgaaaagtat tttagacaat gcaccaatca
     7681 aagatatttg tatcactgat tctgttttca cagaagaaaa tcgtcatcca gaaaacttaa
     7741 caatcgttac atgttcagaa ttaatgggtg aagcggtcaa acgcatccat gaaaatacac
     7801 cgatgagtcc gttattccgt ctggaagaaa aagaattcga ataaacaaaa aaaagaggga
     7861 aagaagttgt gacagaagtg agcagcttca aggagctgcg acaagacttt tgtcacagct
     7921 ccttttttct atgcccatga aacgtcctct agacaaaaat gagctcttct ttggtttgtt
     7981 cgctatttta tgctagaatg tgcctagcaa taatttggaa gggatgaatg aagtgaaaac
     8041 tatttatctg gatcatgcgg caactacccc catgcatcca caagtaattg aagcgatgac
     8101 ggcaatcatg caagacacgt ttggaaatcc ttcaagcata catggatttg gtcgccacgc
     8161 gcatgaaaaa ttggaaacag caagacaaat cattgcagac agtctgcaag caaaacctca
     8221 cgagatcatc tttaacagtg ggggaacaga aggggataat acagctatct tagaaacagc
     8281 gttctcgcgt caaaaagaag gcagacatct aatcactaca gctatcgaac atcctgctgt
     8341 tcttaatacc atgaaatatt tagagacaaa ggggtttgac gttacatatc tgcctgtaga
     8401 tgaaaaaggg aatctgtcga tcgaagaggt caaaaaagcg ttacgagaag atacgatctt
     8461 ggtctctgtg atgtacggga acaatgaaat cggaaatttg atgccaatca aagaaatcgg
     8521 tgaactttta gcggatcatc cagcttattt ccatacagat gcggtacaag cgtacggaaa
     8581 ccaaacgatc catccagaag aattaggaat cgatttatta agtatctctg ctcataaaat
     8641 caatgggcca aaaggcgtcg gtttcttata taaacgagac ggagtaaata tccctgcatt
     8701 gcttttaggc ggggagcagg aagaaaagcg gcgtgcaggt acagaaaatt tagcagggat
     8761 ctggggtatg gcaaaagcag ttgaactgct gtcacctgaa gaacgtgaag cacgtaacaa
     8821 caaatataaa ggattccagc aattgattct tgatacatta gaagcaaacg aaatccctta
     8881 tcaagtaaat ggtgatttaa cgaataaact ccctcatgtg ttgaatcttc gcttaattgg
     8941 cgaagcaaat gatttgctac tgatgaagct tgatcttaat ggggtcgcta tttctactgg
     9001 ttcagcttgt acagcaggaa atatcgagcc ttcacacgta ttagaagcaa tgtatggaga
     9061 agatacaccg atactaaaag aatccatccg tatcagcttt ggtttgggaa ataccgaaga
     9121 cgacatccag tatttccttg atcaattagt tcgtgctgtc aaaaaataac tagtgaagtc
     9181 attcttatat gaacagatgt ctgagagaac gccttcattt tttagggaac ttaactgaaa
     9241 aacctagtaa aaatcaggat aaacttttat aataaagaga aactaatttt atcgaggtga
     9301 aaatcatggc atttgaaaca acagcaacgg tactgggcgc accaattagc tatcgtttgc
     9361 atcctgatgc aaaaagatat acattgcgcg ataatggatt tacagaaaca aacggaggca
     9421 attatcaatt gatccgacca ttagatgcca cgccgcaaag caaagaagga ttcaaattaa
     9481 aaatcactgt atcaaaagat attcaaacat tgaaaatgtc gatcactaca gcaaatggat
     9541 tgaaagcagt caatattttc aaagatccaa aacagaaaat gagccaagat aaattttatt
     9601 ttctgatgga tgggatgatt agccgtgggt tattcgaaaa agtcgaatga tctgtggata
     9661 taaaaagaca actagttttg aaacggccta ttgttagatg actaactttg taaggacgac
     9721 gcaaattagt tgtctttttt atttttaaat ttaacacatg ttgttatttt taatattttg
     9781 ctgatttatt gtttctaagt aaagaaattt aaattgaaac gattgttatt tagggaaaaa
     9841 ggtatttttt gaaaaaagaa tcccgtataa tgattgttgt gcaaacgcta tacaaaatga
     9901 aaaagaaaag agggatgttt atggaaaatg aacagtcggt cgttttaacg aattggaaga
     9961 gaaattattt gttcttttta tcgggacagt ttttgtcagg aatcactagt atggtcgtcc
    10021 aatatgcgat catctggtat ttgacaagag aaaccggttc ggcgacaatt ttgagttttg
    10081 ctactttact aggaatgatt cccatggttt tactaagccc atttgtagga ccgctagtgg
    10141 atcgctggga taaaaaagct cttttgattg tcacggatat tattgtagcg attttcgcgc
    10201 ttattttagc agtagtcgga acgatttcag aatccttccc gatttggcta gtttttgtgt
    10261 ctttgtttat gcgttcggtc gcacaaacat tccaaatgcc aacgatccag tcgattatgc
    10321 cgacaatcgt tccatcttct cacataacaa ggacgaatgg acagttagga atggtccaat
    10381 cagcgaattt catcattgcg ccagctctag gtgcggcttt gttttcagtc gttcctgtca
    10441 attaccttat tttattagat gtattggggg cagtttttgg tgtcggctta ttgatttttg
    10501 tgaagatccc aaaagtttct cctgaaatat tggaagttcc gcttactatt tttaaagatg
    10561 caaaatttgg gctgcagcaa ttgatggata ataaagggtt atggtacata acgatcaatg
    10621 gtgcatttgt gatgctgttg ttcatgccag caatcagtct gtatccattg atgacgctag
    10681 attactttgg tggttccgtt ggacaggcgg gagcagtgga agtagtctac gcagtcggaa
    10741 tgctcttagg cggtgcactg atcagtttta taggaacatg gaaagaccga atgaaaccta
    10801 ttattatagc ctacatcatt atgggcctga cgatcggtgc aagcggattg gttccaaacg
    10861 atagtcaagg gttcttgtac tttcttatct tgaatgcagg agcaggttgt gcaacgccat
    10921 atttcaatac actgctgatg gcaatgatcc agcagagtta tgaatcgaat gttttaggtc
    10981 gtgtcttagg gaacttcaac tctttgatga acctggcagg tccaattgga ttattatttg
    11041 caggaccatt agctgatcgt ttaggggtag aaaaaatgtt cttgttttcc ggaatcggga
    11101 ttttattatg cggaatcgtt ttatttttaa cgtcagctgc ccgaaattat gataaagaat
    11161 tacagaaaaa actggtaaaa gaacaccatg agcaaaaaga cgaatagtat ggaatggagt
    11221 tgtgacagaa gtcttgttac aactccattt ctgatcctaa tgttcctgtg gcaataagcc
    11281 tactcaaatg aaaaatatga gtaattatct ttatttgttt aatacttgat atagggcagt
    11341 tttttcacga cctatcgtac ttcctctttg cttcatagat ttctttgatt tgttgctcag
    11401 ataacggagt gccaaatggt agtttttcct ttaagagttc tctttccggt gcgtctacgc
    11461 ctacattgac atcgttctcg ataggtacgc tgtaatgatg gatatgtcca tgaagattgc
    11521 ggatagtgtc gttaggcccg agcaacatcg gataatgagt caagtaatat tgttgatggt
    11581 cgaatttaac gatggcacct acatcataaa aataaaattt gggacttccg tcagtaagcc
    11641 taggatcatt tttttctaaa taacggaaaa aagcgcgact gtcatggttc cctttgatca
    11701 agtggattgt tccttgcagt tgagtgacca gttccaaaat ttctgcattt gctttttcat
    11761 attgcggatg catagcaagg tcgcctagat gataaacatg gtcggtttct tttattactg
    11821 cattccagct agtgatcaac tgttggttca tttcatccac atttgcaaag agccgcggag
    11881 caaagtcgtt ttttcctaat aagcgttcat ggaaaaagtg catatcactg ataaagtaat
    11941 tcatgtatct tttgcctccc ttttttctta gagtaaacaa aatcacttat ctgagcaact
    12001 cataacatct aaaaagaaaa ggttgtaaat gagacgtgca gctttaagcg ataagaagca
    12061 attttgaaaa atagtttttc acaatttata aaattattcc ttattgccga aaggctggcc
    12121 ctttttatga gtatgccaat tttttatatc gaatgctcaa aagatgagtg attttttggt
    12181 tgactatcat gtttgtgtac tgaataggtc cagtagaaca gtatttttac gacttgataa
    12241 ttaagggatg aaattttcag aaatatgacg tataatgtaa aatactgaaa agttgcgacc
    12301 ttcaactcgt agatgtttca gaatctaatt gaaatgatgg tgatatcatg acagacaaca
    12361 gcaaaacacg cgttgtcgta gggatgagcg gcggtgtcga ctcatctgta acagcacttt
    12421 tgttaaagga acaaggatac gacgtgatcg gaatattcat gaaaaattgg gatgacacgg
    12481 acgaaaacgg tgtatgcacg gccacggaag attataagga tgtagcgaaa gtagctgctc
    12541 aaatcgggat tccttattac tctgtgaatt ttgaaaaaga atattgggat cgtgtatttg
    12601 aatatttcct agccgaatac cgcgcaggac gtacacctaa cccagacgtg atgtgcaaca
    12661 aagaaatcaa attcaaagca ttcttggatt atgcaatgga tcttggcgcc gattatgtag
    12721 ctactggaca ttatgcgcaa gtcactcgcg atgaaaacgg cgtggtccac atgcttcgtg
    12781 gagtagacaa taataaagat caaacttact tccttagcca attatcacaa gaacagcttt
    12841 caaaaacgat gttccctcta ggcggcatgg aaaaatcaga agtacgggca attgctgaac
    12901 gcgcaggcct tgcgactgct aagaaaaaag attcaacggg aatctgcttt attggtgaaa
    12961 agaacttcaa acaatttttg agcaactatc tgccagcaaa aaaaggaaat atggtcactc
    13021 ttgatggtga agtcaaagga caacatgctg gcttgatgta ttatacgatt ggtcaacgtc
    13081 aaggactagg gatcggtggc ggaggagatt cgcaagaacc ctggtttgtt gtaggaaaag
    13141 atctagcgac aaacacatta tatgtggggc aagggttcca tcatcctgca ttgtatgcca
    13201 caagcttgga tgcaagtgaa atccacttta cgacgaatga accaatgcca aaagaattca
    13261 agtgtacagc gaaattccgt tatcgtcagc aagacgttcc tgtgacagtt cgcttattgg
    13321 atgataatcg tgcagaagtc gtattcgacg aacctgtacg tgcaatcact cctggacaag
    13381 cagttgtatt ttatgatgga atggaatgtc tgggtggtgg tttgatcgac cacgcatatc
    13441 aagaaacaaa agttttacaa tacgtttaag cgatattaaa tgaatcaaaa cagctatggc
    13501 taacaaaaga aacacctttt cttttggata gcatagctgt ttttttgcaa taaaattaat
    13561 ttttattcat tttatacttg aaatacttgt gtaaaaagtt cataatatcc aataatatga
    13621 ataaagttgc tttttgttaa gcaagagcag ttgcaaaata gaagggaatc ttttgcaagt
    13681 gatttgttca attttataag tgagggtgat ggaaatggaa aagaaatcga cgggtattag
    13741 caaatgggga ctggttgctc tggttgtcag ttcgtcaatc ggaagcggtg tgtttgggat
    13801 cacaagtgat ctggctagtt ctgcagctcc agggccagcg atcctttcat ggataatcgt
    13861 tgggattggt attttagctt tggtattatc gctgaatcat ttaggagaaa agcgtccaga
    13921 tctagatggt ggtattttcg gttacgcgga agcttcattt ggtaaattag gtggcttcat
    13981 cagtggttgg ggttactggt tgtctgcgtg gctgggaaat gttgcttttg caacgatgct
    14041 gatgagcgcc atgggagaat ttttcccgat attcaaaggt ggacaaaatg ttccttctat
    14101 tttatttgca agtattttta tttggggtct gactttatta gtaaacaatg gagttgaagg
    14161 agcgagcgtc atcaatacaa tcgtgacgat ctgtaaatta gtgccattat tcctattttt
    14221 aatatttgta tttatcgcat ttaaagtgaa tatattcact gctgattttt ggggtaacgt
    14281 atctgataat ctagtgaatg gaacagggca gcaaggaacg atctggttgc agattaaagg
    14341 ttgtttgatg gttatgatgt gggtctttgt agggatcgaa ggcgcaagtg ttttagccaa
    14401 ccgcgcgaag aaacgttcag aagcccagca agcatcgatc attggtctgc tttgtttatt
    14461 gtttatctat atccttgctt cgatcttgcc atacggcgtc ttatctcaag aagagttagc
    14521 aactatttca caacctgcta tggcaaatat tttaaaagga atcgtgggaa attggggagc
    14581 agcgctgatc aatatcggct tgattatttc gatcattggt tcttggttgt cttggacgat
    14641 gctcccagca gaaacaacga tgttgatggc tcgagacggt ctgttgccga aaggttgggg
    14701 aaaaacgaat aaaaaaaatg ccccaactta ttcgttagtt gttactgcaa tcttgactaa
    14761 tctattctta ttgactttct tagttactga ttatgcctat caatttgcct attctttatg
    14821 tacagcggca attttgattt gttatctact tgtcgggatc tatcaagtcc agttttcttt
    14881 aaaagaagga atcaaaaaac aagtagtgat cggtgggatt gctgtagttt ttgaattgat
    14941 gggcatcatt ttagcaggat tttcttatgt ccttttatgt agtattgcct atcttcctgg
    15001 tttttgcttc tactggatcg cttgtcgtga aaccaaacat caaattacgg gaaaagaaaa
    15061 agtaatgatt gggctgattt gtgtggccgc actgctttca atcgggttgc ttgctgtagg
    15121 ctggatcaag atataagggg gaaagaaaca tgaaaatcgc aaatttcggt gtagaagaat
    15181 ggctaaataa atgggaaaag aaagcggtat atgatattgc acaaagctcg atcgaagcat
    15241 tgacattaga cgaactcgtt ggcttagatg ggactagcgt aagtaaattt ttcgaaaaac
    15301 gcaaaaacga accattggac tatggctgga tcgaaggatc agatgttttc aaacaagaag
    15361 tcgcttctct ttatcaaacc gtcgatccgg aaaacatctt acaaacgaat ggagcgactg
    15421 gtgctaatct tttagctcta tacgcgttag tggaagcagg agaccatgtt gtttcgatgc
    15481 ttcctactta tcagcaatta tatgacatcc ccaaatcttt aggtgccgct gttgactttg
    15541 ttcatttgaa ggaagaagaa gattggcagt ttgatttaga acagctagaa gccttagtca
    15601 aacctgaaac aaaaatcatc tgtttgaata gtgcaaacaa tcctacaggc acattgctag
    15661 atcggaaaac tttagaaaaa atcgcagaaa ttgctcgtac agtagatgca tatgtattga
    15721 tagatgaagt atatgcgcct ttaacggata aaggtgaatt cttgtcgatc gtagatgtct
    15781 atgaaaaagg tatagcaacc aattccctat ccaaaaccta ctccattcca ggtattcgta
    15841 ttggctggac agctactgga cctgagttgg cagaagtttt tcgaaagtat cgagactaca
    15901 cgatgatttg cggcggagtc ctgtcagatg atcttgctgt acatgcattg aagaataaag
    15961 aaaaaatatt ggcgcgaaac aaaaagatca ttacagagaa ccttgtgatt ttaaaacaat
    16021 gggtagccaa tgaaccgaaa gttgaacttg tcgctcccaa ttacgtctct acttctttca
    16081 ttaaattagc catcgaagaa gatgaccaga cattttgtat caatttatta gaagaaacag
    16141 gagtactatt agtaccagga agtgcctttg atttaccgaa gcatgcccga ctaggttact
    16201 gttgtaaaaa agaaaccttg gaaaagggat tattcctctt atctgagttc ttgaaaaaac
    16261 aggcctaaac aaaaacactg caaggacagt ctgtgacaac tgttcaagca gtgtttttca
    16321 tttacgctta ttgtctatga gaaggagagt gccctgaagc tatggagact cctgaagctt
    16381 tttcttctgc agtttcttgc tgatggatct cttgtgtatt gtgtcgtaca agcaagaagt
    16441 tgaccaaaac aagaagagaa gtcgaaagaa agacgccacg ataaccaaat gcactggaaa
    16501 cactggagcc gatcataggc cctactacgt taccagttgc ttggaaagat tggttataac
    16561 tgaagatccg tccagcagct tgatgaggcg aatattttgt gatcaatgct tggacagcag
    16621 ggagcagaca agcatcagag ataccaatca aaaaacgtaa ggcagctaat tgccaaacat
    16681 tcgtgacgaa tgccattggg atataaacca gaatcgcaaa acccaaacca atcgcaagta
    16741 ttctttcact cccaatcttg tcacctaagc gaccaaatct tggagcggct atcaaagtgg
    16801 caatcccagg tatcgaagca atgattccgc tgatcaacgt aacattccca tgtccatgca
    16861 gcaattggcg aatgtacaga ctgatgattg gactaatgga attgttggat gcttggatga
    16921 tcatcgttgt gacgaacata ccgatgacga cgtgtggata tttcaagtct ttgaaaatct
    16981 gtttggcaga aaccatgttt tcttttttca ctgggacaaa tttttcatgg acgaaaaaca
    17041 gactcaacaa gaagacgaaa aataagatga tccctgtaat gaaaaaggta gggcgatagc
    17101 caaacgctga agcagagatc ccgccaagaa gcggtccaag taatgttcct gtaacagaac
    17161 cagttgctaa ggttccaaga acttgaccac ttttttcttt tggcgtccca gttgcgacaa
    17221 gggcagtggc attactgata taaccagaaa aaatcccttg aagcagacgc aatgcgacta
    17281 attgatacac actagtcacg caacccatca aagaaatgac gattgccatt cctaatgaag
    17341 cacgcaacag catcaatttt cttccttttt ggtcggctaa ttttccccac caaggagaga
    17401 taagcgtagt caccaagaaa gtagatgaaa aagtcaatcc gctccaaaag ttcaattgtg
    17461 acgtactata attacctaac gtatctatgt aaagtgacat aaaaggcatg actaaactaa
    17521 atccgatacc agccataaat gttccaaacc ataagacaaa caagttttgt tcccaagttt
    17581 ctcttttcct aaataatttt tcctttattc ttgcagccaa ttagactcct tctttctgaa
    17641 aattttcatc tacagctctt tattataaac tacaatatgt agtttatcaa tgaaagtctc
    17701 ttttttctct ttctttttcg tggtaaactg aaagagtgaa ggatttattt tatgagagga
    17761 aacatggaaa tgaaaaaaag aaatctgtct caagagaaaa tcatcgactg ctttcgagaa
    17821 ctagcagaag agatggatgt tcagcaaata acctttcagc atttagccaa acgcttggat
    17881 atcaaggctc cctcgctgta taaccatttc aaaaatattc gtgatgtcaa aacagcgcta
    17941 acagcgaaac ttctgcagga acttaatgac cagctgcgac gggctcttgt gggaaaaagt
    18001 ggtcaggaag cactgcagat ctatgcagaa acttatcgat cctttgcttt ttcaaatcaa
    18061 gcagtgtatg agttactgat cagtgtaccg cataccaatg aagctgtttt attagatgga
    18121 atccatgaaa cgaatcagat cattttgcag atatttgagg cttttcaatt aacgaaagaa
    18181 gaaaaagttc atcgaagcag ggaacttcgt agtatgatcc acggttatct ttccttacgt
    18241 tttttaggat actttacaaa agaaccaaca atcgatccag aagacagcta tttttggatg
    18301 atcaataact ttatcgctac tttgccttaa acaatcagat tcatttgtaa caattttaag
    18361 atgttcatta aatgaccctt ttataagaga aaattcttgc aactttcttg aaaagtgact
    18421 aagatgagtc tagaaaagct gaaagaagga gcacgagtat gtatcaagta attaccatgt
    18481 tcggggacaa tgagccttgg tggttttttg aagactggga agaagatatt gaagaagaag
    18541 aaacattcga gtctttcgaa gaagcacgac aagcgtacga aaaacaatgg aacgaaatcc
    18601 atcaaaatta tgaatatatc aatgcaaaaa gtaactttct cagcgccttt tggaatgacg
    18661 gagatgagcg ctggtgtgaa gagtgtgacg atgatttaca gcaatacaag ggacttgcgt
    18721 tgttgaaaaa tcatcagccc atcacagtag aaagcagaaa ggaattttat gaaacaacta
    18781 attctagcgg aaaaaccaag cgttgcgaaa gacctaagca aggtgcttgg tgctaatcaa
    18841 aagcacaaaa attattatga aggacccaag gtgatcgtta cttgggccct tggtcattta
    18901 ttaggattga aaatgccgga agatctgaat aaggaatggc agagctggca aatggacacg
    18961 ttgccaatga tccctaaaaa actaggaatc aaaccacttc ctaaaacagg acatcaatta
    19021 aaagcaatca agcagctggc tcagcgaaaa gatgtctcag aagcagtcat tgcgacagat
    19081 gccggaagag aaggggaact tgttgctcgc tggatcttag agtatgtgca tttcaataaa
    19141 ccagtgaagc ggttatggat ctcttctcaa acagataaag caatcaaaac tggattcaag
    19201 caactaagac ctgcgaaaga atatgatgca ttgtatgaat ctgctcttgc ccgggcaaaa
    19261 gcggactggc tggtaggatt gaatgtgacc agagccttaa ctgtgaagta cgcggataat
    19321 ttatcagcag gccgtgtgca gacaccgaca ctagcattag tgagagacca agaaaagaaa
    19381 atcgagcagt tccgtccaca aacgtatttc acgatcacgt tgcaagctgg aaaagaacaa
    19441 gccaaaatgc ttcaaaaaaa tcaatttgct ttaaaaacac aagaagaagc acaaaaactt
    19501 gttcaattga tcagtacaag caaaggaact gtcacagaag tccaagaaaa attaaaaacg
    19561 gaatctgcgc cattgcctta tgatttaaca gagatccaaa gagaagccaa tcaacgctat
    19621 ggctattctg caaagaaaac attaagtctt gtacaaagtt tgtatgagac ccataagatc
    19681 gttacttatc cgcgtacaga cagcaaatat ctgacaaatg acatgaaaag tacgatgaaa
    19741 gaacgattgc aagcagtcag cgactttgct cctgaggtca agcagtattt gaaaaacgga
    19801 gccatcgtcc aacagacaaa agtattccaa gacagtaaag tgaccgatca ccatgcactt
    19861 ttgccaactg aaaacagagc acgttatgaa aaattaagta atgaagagcg aaaaatctat
    19921 caaatgattg tctctcgttt tttaggactg tttgctcaac cccataaagt cagccaaaca
    19981 aaagttacgg ttgaatttgg taaagaacga ttcatttttc ggcaaaatcg tgtcgtccaa
    20041 gcaggatgga aaggcgaaac tgaaactgag acggaaacag tcaaatggga aaaaggaatg
    20101 agaatcaatc ccgatttcgc catcaaaaaa gaactatctg caccgcctaa accattgtca
    20161 gaagcaagct tgcttggtca aatggaaaaa tacagtctgg gaaccccagc tacgcgtgca
    20221 gagattatcg agaaactaat caaatctgaa ctgatggaac gtacccctca aggattgcaa
    20281 gtatctccta aaggtaagca attattagta ttggtaaatc cctctttagt aacaccagat
    20341 ttgacagaaa gctgggaaaa agaccttgaa gctattgctg caggaaagaa acaagcagga
    20401 accttcttga atggaatcga aaaagaaaca aaacgcttgg tgaatgagat caaatcaagc
    20461 aaacaagaat atcaagattt ctcgattacc caaaagaaat gcccagaatg tggggccaat
    20521 ctgcgcgaga aaaacacacg tgacggcaaa atctatgtct gcaccaattc agattgcaac
    20581 taccgcagaa gaaaagatcc aaaagtctct aatcatcgat gcccgcaatg tcaccggaaa
    20641 atggaaatca tcgaaggtaa aaacggtgct tatttccgtt gtaaatacga tggaacgaca
    20701 gaaaaattgc ttgataaaaa agagcagaag aagaaaatga ccaaacatga agaacgacgc
    20761 ttgctgaaaa aatatgcaca agcagaagaa ccagaagaaa gcccattagc agcagcacta
    20821 aaagcagcaa tgaagaagta ataagatatg aaagaggttg tgatagaagt ggtcagcttc
    20881 aagaaataag aaggaattta cgaaaattgc ttctcaaatt tttgtgaaat ttcggcttat
    20941 ttccgaagaa gctacttctg gaacaccatt tattcggaaa aaaggactgt gacaagactt
    21001 ttgtcacagt cctttttcat ttaaaaaaat gtttacttca tttgacgtat attattggtg
    21061 aggcttcaat tcatttggct tcactttttc tgtttctctt atgatataaa caggacgctg
    21121 tttcgtttct aagaagattt tcccaatata tttcccgatg attccaagac ataacaattg
    21181 gattccacca atgaacagga agatcgagac catggaaggc catcctgatg taggatcacc
    21241 aaacaacaat gcccgcaaaa taatgaacaa aattgcaata ccagaaccga cacaagacaa
    21301 agcgccgata aatgaagcaa tcgttaacgg tgcatccgag aagttcacga taccatcaat
    21361 cgagtagttg aataatttcc agaaggacca agatgtttcg ccagccacac gttcgcggtt
    21421 ttcataagaa atatattctg ttttaaatcc gacccagcta aataatcctt ttgaaaatcg
    21481 gttgtattct gttaattcta ggacggcatc caccatttga cgagtcatca agcggaaatc
    21541 acgagcgcca tcgaccattt ctgtatcgct gattttattg atcaactggt agaatttttt
    21601 cgcaaagaaa ctgcgtatcg caggctcgcc ttcacgagtc gaacgccggg tgccgacaca
    21661 atcgatatca gaagtagtga tccggttgat catctcagga agcagttcgg gcggatcttg
    21721 cagatcaaca tccatcacgg tcactaaatc tcctgtagaa gcttgcaatc cagcgtacag
    21781 agccgcttct ttcccaaaat ttctggaaaa tgagacaaag cggacataag gataagctga
    21841 ggctagcttc ttgattgctg ctaacgtacc gtcttttgat ccgtcgtcaa taaacaaata
    21901 ttcgaactca tgggcacctt tgaatttttc aacctcatca aaaaaaagag gaacagtttt
    21961 ttcttcatta aaacatggga caacaattga tactttcatc gtttctatcc tttcaatcgt
    22021 atgtttatat atggtttaca ttcaaaattt aataaacctt aaataacacc tttaaaattt
    22081 gattttacgt aaaagaacag gtattctttt tgtaaactaa cgtatttagt ttaccatgtt
    22141 tcctcggttt atcaaacttt taagaacaat ttttattagt tggcaagtag ttttggatag
    22201 agaaaaagga ggaagttcca gtctattgac taggagcaaa caaaatgaaa atacacacac
    22261 ctatcggctt tttatggtta gatgcagatg aatccggatt gactgctgta tcttttcagc
    22321 caatttcaga aagcgaatca gcgaatcagc gaattttaac gcgcacacaa gaacagtttg
    22381 aagaatattt tgcgggaaaa agaaaagaat ttgatgttcc tttatctata aagagaggta
    22441 cgccttttca gcaaaatgtc tggaaagctt tgtcgaccat tccttatgga gaaatccgaa
    22501 cgtataaaga agtagccgtt gctgttgata gtccgaaagc tgtgcgagcg attgggcagg
    22561 caaatcgaac caatccattg ccaatcgtta ttccttgtca tcgagtgatc gggcaaaatg
    22621 gaaaactgac aggatatatg ggaaacgcaa tagatggggt tgaaatcaaa cgccaattgt
    22681 tgttgttaga aggatatctg caaaattaaa aacagttgtg attcggacat tgttccatgc
    22741 gagaatcaca actgtttttt catgttcatt ctaaactttg atcagccaaa taaatagtaa
    22801 agccatcact gtttggagaa gcccgacagc taatccataa gataagaagc gtgtaccttc
    22861 tttcatgaat tttgcaaagt ctaaacgcag accaattgcc gctaaagcag tgatctcaaa
    22921 ccagctgctg ataaaatgtg ccgattggtc aataactaca ggtaaagaaa acaagctgtt
    22981 gaccaaacaa aagatcacaa accctaatac ataccaagga agcggtaatt ttcgtttttt
    23041 ctgcgtatca gttggcgttt caaacagagc tggttgtttc ttgtgcatga atttttcaaa
    23101 cagatagaca acaacaacga gcatcataat acgtagaatc ttaaatagca tggcgaattc
    23161 gacaacagaa ttgtcaagta agcttgcccc agcgactact tgaccaacag attggagtgt
    23221 accacccaaa agtgcacttt tttcaatgag atttccacca aacaactgta atccaagaaa
    23281 agggagagtc aacatcatca cagtacccag tagattgact agtgtgatga tctgtccttt
    23341 ttcttcctct ttcgcatgga tggaaggggc gattgaagca atagcagaag aaccacaaac
    23401 agcgtttcct ccagccatca tcaaagaaga agtatcgctg aattgcagtt ttttaccaat
    23461 caagtaagca ccgatgatag tgactgacat ttgcagtaac acaaaaacaa ttccttttac
    23521 accaatttga gcaatcgttt gagctgtgac agttgcacct agtaaaaaaa cagagaattc
    23581 taatagtttg ctttcagcaa attttgtgcc gattgctaga acaggctgtt taaaaaaagt
    23641 atttcctaat aaaataccca ataaaatagc aatagtcgct ccacctaact gtggcagata
    23701 aatagcaaga agcctgctga aggcagcgat ggcaaaagaa agcagtaaac cgggtaagat
    23761 ttcgcggacc gctgaatcct ttacagattt tattggatgt gacaatgatt tcatttgatc
    23821 ggttcctttc gtcaataaat actaaaagca tactcgaaca tagtagcact aaaccagtat
    23881 tttgacaaaa gaacaagagg tcgtgacaaa agtcttgtac gacctcttgt ttcgaataaa
    23941 cggtgttcca gaagtagctt ctacggaaat aagccgaaat ttcacaaaaa tttgagaagc
    24001 aattttcgta aattccttct tatttcttga agctgaccac ttcttttacg acctcttggt
    24061 aaacggtgtt caaaagcttg catctgcggt aataagccca accagtacaa aaacatgaac
    24121 agctgttttt gtttggccgt tcttattact tgatgcagaa cagctttttc acaacctatt
    24181 gaatcgatta ttaagcgatt tttttagaaa caaattttcc atgtttgcta tgttctttaa
    24241 ttaagaaacg tacgtaatga gcaagaacgt agaagacaac tacacttgca aacagacatt
    24301 ccgcaacttt taagaaatcc aatacgctac tatagatacc taaactgttg aagtaatgaa
    24361 cagtagtaaa tatagctgtt gcagagataa caagcgggaa tgtaaaggct gcatagcttg
    24421 gataaaaacg aagcttgaac aaacgtggaa gcatagacag cacaacgaaa tacaatactt
    24481 gagataaagc gaacaatgct acgacaagat aaaaattagg ttcagcaaag tttttaagat
    24541 aacctgttag gcaaagagaa ccaggtgctg caacgatcgt aatcagcgga cgtgtcggat
    24601 gagccatatt tcttacgaaa aagacacgtt tgatgatgat cggcaataag aacgcatagc
    24661 agatcaatga aatccaaaag aaaatttttc caataagtgg gaagaagttc ccggcagtta
    24721 cagtgatgac cccaaatcca acgtaaatga taaaccagct tggataaatt gcttcaattg
    24781 aaagatcagc tttgataaca tggtgataat tgaaataaaa gacaaggatc acttggaaga
    24841 taacagcgca cagccaaatg aatttgacaa ttggtgcaat actttcatat gaaacaaaat
    24901 aagtacaaat aaccatgagt gacatcgtaa aagttggtga aacggaggcg atgattggat
    24961 catgcaacgt ttgtttcgtg tgttcgaata agataaacaa tttaacaaaa atgaatatca
    25021 taagaatcat agagataccg ccagttagat tgcctaaagc aacatggtga tagtctttaa
    25081 acagatttcc aagggaagct aacccaagga tcaacccgca gatcgggatc ggaataattt
    25141 tcaaaaagtt cttcatatat aatattctcc tttttattta atagatttta gtaccaagat
    25201 gaacgaatac attgtaaaat gaataggaat gtatgattac gagcaagcag acagctgatt
    25261 gtcttcatct aagttactag ttggatcagc aactgttttg ttgtacattt ctattataga
    25321 tggttttttg tatatttaaa tcaaatagtt tttatagtaa ttatcataaa aagttatgga
    25381 agtggtgcca tgtttaagtt attaacgact tttcgagcag tatatgaaac aagaaatttt
    25441 tccagagcag cagaagtact gtttttatct caaccagcag tctcgaatca aatcaaacag
    25501 ttggagcggg aattgaatat cgatcttttt caacgtaacg gaagaaaaga gatgcttcca
    25561 actaagcaag ccgacttatt atatgaacgg acactggttt tgttagaaga atgggaagaa
    25621 actcagcaaa aattgctcaa tgaacaaaat gaagaagaag tatgtcggat cgttgcttcc
    25681 cacacctttg ctgtctatct tttgcctcag ttgatgaaac atctgatcaa aaggtttcct
    25741 aaagtgcatt ttgagatcga aatcacgaat tctcatgaat cattagaaca agtagcgaaa
    25801 catgaatccg attttggttt tatcgaaaag ccattagaga cttccggcgt acaaagatac
    25861 tctttgatgg aagaccagct agtcatcgct ggggacccaa aaagcaaatt gtggcttgta
    25921 agagaagcaa actctggtgt ttttcattac acgcagcgtt attttgaaga gatgaatatc
    25981 caagataaga agatgatcgt gaaaagtaac gatgtaattg ttgcgttgct gaaggaagga
    26041 atcggtcgct cgattttgtc taagcgctct gttccagaaa atgtgccaat gactccgttg
    26101 aatttccatc gatattttta tttcatccaa cgaaccaatc tggtttctga tcagctgcta
    26161 gagattgccg aagagatcct tcgatacaat gaaagcacag aaacttctca cagcgaggag
    26221 aatctcagct ggtagataat tgcatgtatc aaaaaaagtt ctatgataca ctaaagataa
    26281 gcagtaggct tttgtactgc atttgctcaa gcaactgcac aaacggaaag ttaatttttc
    26341 ccaaatgtct atggaaagac tttccattat ctaactggac cgctataata atcagcagta
    26401 tggtttttaa gaaaagggat gaaacatgga aaaaaaatta aaagcttcga acgataatcg
    26461 tattgattat ggcgtgattt taccagtctt tctgttatgt ttgattggtc tgctctcatt
    26521 atatgtagca cttagccatg atccgaacaa tccagcagtc ttgaaaggcg tagggatgca
    26581 agttgtctgg tatttagttg gagcggcagc aatcgttgtc atcatgcatt tgaattccaa
    26641 atggatctgg aaactgactc cttaccttta tggtttgggg ttagtggtaa tgggactctt
    26701 gctcaaattc tatgatcaga atttagctgc ttcaacaggg tctaaaaact ggtttcgatt
    26761 cggtgcgttt actttccagc cagcagagtt gatgaagatt gcgtacatct tgatgatggc
    26821 actgatcgta actaaacata atacgcaagt aaaagaacgg acgatgaaat cggacttttg
    26881 gctgattggg aagctcttga tcgtgacaat accggtttta gcattgatca tggcccaaga
    26941 tgactttgga acgatgcttg tctttcttgc gatctttggc gggattttcc tgatgtctgg
    27001 aatctcttgg cgcatcatcg cacctgtagt aatcttggca gtagtcgttg gagcaggaac
    27061 gatcttcttg gttacgactg aaggcggaag agacttgctt tataaagttg gattcaaatc
    27121 ttatcagttt gcacgtattg attcatggct ggaccctttc catgatacgt caggaatgag
    27181 ttatcagccg gcccaaggac ttttggcaat tggtaccggt ggcttgtttg gtaaaggatt
    27241 caacgtaagc aatatctatg tgcctgttcg tgagtccgat atgattttta ccgttatcgg
    27301 tgaaaacttc ggctttatcg gtggtgcatt cgtcattttc ttgtatttta ttttaatcta
    27361 tcgtatgatt cgggtgtgtt tcgatacgaa taatgaattt tacgcctata tcgcaagcgg
    27421 tttgatcatg atgctgctgt tccatgtctt tgagaatatt ggagcaaata tcggattact
    27481 tcctttaaca gggatcccat tgcctttcat tagtcaggga ggatcctcga ttttagggaa
    27541 catgatcggt atcgggttga tattatcgat gagataccaa aatgaagcac ctgcaagatc
    27601 ttcaaggagg taagaaaatt gtacaccttt tactggtacc cgaaatgttc aacatgcaaa
    27661 aaagccaaag cgtggttaga ccagcatggc gttagttatc aaaccgttga tatgatcaaa
    27721 gaagtaccga aggcctcaac gattgagact tggctagaaa cgagtcaagt accaatccgt
    27781 cgcctgttca acacaagcgg gatgaaatat cgggaacttg gactgaaaga tcaagtaggc
    27841 gagtttacgg cttcaaaagc gagccaagtc ttatcgacag atggtatgct gatcaagcga
    27901 ccactgatct tacgagagga ccagcttgtt gcaattggat tcaatgaaaa aatttatgaa
    27961 ggagaactga tataaaatgg caggcaagca tttgaagaaa aaggacaacc tttggatctt
    28021 atttaatgga aaagaatact gtgttggttt gacaaatgaa gcgcaagaag aacttggaga
    28081 catcacgttt gccaatctgc caaaagcagg acaatcgcta aaaaaagatg aacctctgat
    28141 cgaagttgaa gcggaaaaag cggtcaatga atttgccagc ccgctaacgg gtacagtttc
    28201 ttctgttaat gataaaatcg gtgaagatat caatatcttg aatgattcag atgaaatgaa
    28261 tgcgtggatc ttaagtttca aagatgttga tccaaaagaa tttgacgaat tataaaatca
    28321 gaaaatcact tgaaaaaagt tgacactgat tcttccagtt gctataatca taagcaatcc
    28381 tatatgaaac gagaaagctt tgaaaagaag agtacatgtc acggacgttt gaagagagcc
    28441 ctgtttgctg aaaatgggta acgaaaatga gatggaagat ggtcttagag cagagtaagc
    28501 gagcgtaagc aaacttacta cgggagtgcc cgttacagcg cgacagtata cggaaagaag
    28561 ctaagtccaa gtactggaag aggctgttat tgcgaagtaa cggtaaatca aggtggtaac
    28621 acggaagttc aagctttcgt ccttttgctt aaggcaagag ggcgaaggct tttttgtttg
    28681 aaaaatcata agagaaagat gtgaatggca tgtcattaat ccaactaacg aatgtcaaaa
    28741 agacattcaa tgggaaaaac ggaaacatcc aagccgtcaa tgacgtttca ctaaacgttg
    28801 aaaaagggga tatttatgga atcgtcggct attctggcgc aggaaaaagt acattagtcc
    28861 gtctcctgaa tggacttgag cttcccacga gcggcgaagt gatcgtaaac gatcaagata
    28921 ttacaaaatt aaaaaacaaa gaattacgta cattccgaaa gaaaatcggt atgatcttcc
    28981 agcatttcaa cctgttatgg tcaagaactg tacttgaaaa tatccagctg ccgctggaat
    29041 tagctggcgt accaaagagc aaacgtaaag aacgggcaga agaactgttg cgtttagtcg
    29101 ggttagaagg acgcggacaa gcatatcctt cacaactttc cggcggacag aaacaacgcg
    29161 tcggtatcgc acgagcattg gcaaatgatc ctgagatcct gctttgtgat gaggctacta
    29221 gcgcattgga cccgcaaaca acagaagaag tattagactt attgttagcg atcaataaga
    29281 aattgaattt gaccatcgtc ttgatcacac atgaaatgaa tgtgatccgc aaaatctgca
    29341 acaaagtcgc tgtgatggag ttggggaaag tcgtagaaga aggagacgta ttgactgtct
    29401 tcagacaacc gaaaaaagaa gtaaccaaac gctttgtaca acaagacatc gaaccagaag
    29461 ctgattcgac agaactatta gctgaactca tcaaagaaaa tccaagcggc cgtttggcaa
    29521 ctttgacctt tagcgaaaga aatgccaacg agccagtcat ttcccaagcg attcgacgct
    29581 ataacatcga tgtcaacgtt gtgtatggaa agatcaaaca agtgaaagaa ggttcctttg
    29641 gttcattgac tgtcttgatg actggtgaaa ccaaagaatt agatcaagca gaagtgttca
    29701 tcaaagaaca aggagtagga attgaggtga tccatcgtgg ataaaagctt ttcagaaaca
    29761 tatctagatt ttaaacaaat caacccggaa acgatgaatc aggctatcct tgatacacta
    29821 tatatgacat taatctcaat ggtcttagtg acgatcatcg gattagtttt gggattgatc
    29881 ctttactcta ttggacgcaa aaacaaaccg tatgctcgaa tcatttatgg aatcgtatcg
    29941 atcatcagta atattttccg gtcaacgcca tttatgatcc tgatggtttt gatcattcca
    30001 tttactaaag caatcgtagg cactatgcta ggtgcgcaag cagccattcc agctcttgtt
    30061 ttatccgcag caccatttta tgcccgtcta gtagagattg cttttcgtga agtcagccct
    30121 ggtgtactgg aagcagcaga tgcaatggga gcaagttact gggaaatcat ctggaaggtc
    30181 ttgatacctg aaagtattcc cgcattgatt tctggattaa cagttacaac gatctcgatg
    30241 atcggattta ctgcgatggc cggcgcgatc ggcgcaggtg gacttggagg tcttgcttgg
    30301 caggaaggct accagcgtgg taatctaaca gtgacattcg ttgcgacttt aattatttta
    30361 ctaatcgtat ttatcgttca aggaatcggt gatttcttaa ctaagaaaac agacaaaaga
    30421 taataggata tagggggatg taggatatga aaaagaaaat ttttggattt gcagcagcgc
    30481 ttttgctgac tgtaggatta gcagcatgcg gtaacaacag cgacagcaaa gattcagcaa
    30541 ataaagcaga cgacacgaca ttgaaagtcg gcgcttcacc gacaccgcac gcagagattt
    30601 tggaacatgt gaaaccatta ttgaaagatg aaggaatcga tcttgaaatc gtcaaattcg
    30661 atgactatgt attaccgaac caatctttgg aagaaggcga cattgatgcc aattacttcc
    30721 agcatattcc ttatttgaac aaagaaatca aagaaaaagg atatgacttt gtcaatgccg
    30781 gtgctgtcca catcgaacca atgggcttgt actctaaaaa agtcaaagat gtttccgaat
    30841 taaaagatgg tgcaacaatc attacttcaa attctgaatc agactgggga cgcatcatca
    30901 caattctaca agatgctggc ttagtcaaag tcaaagatgg agtagatctg gaaacagcaa
    30961 cattcgatga tattgaagaa aaccctaaga acttgaagtt caaccatacg atcgacccat
    31021 cacttttagc ttctacgtac caaaatgatg aaggtgacct agttgcaatc aacgcaaact
    31081 tcgcttacgg cgcagggttg aatccattag aagatgccgt attgcttgaa aaggacaact
    31141 ctccttacgt gaatattatt gcgactcgta aaggtgatga agacagtgac aaaatcaaaa
    31201 aactgattga agtgcttcac cgcaaagaag tccaagaatg gatcacagac aaatggggcg
    31261 gctctgttaa accagtaaag gctgatgcaa aataaggtat ggaacaaaaa agatgagaaa
    31321 taagtctgta atggcttatt tctcatcttt tttatacc
//
LOCUS       DACDAF010000022        29759 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.022, whole genome shotgun sequence.
ACCESSION   DACDAF010000022 DACDAF010000000
VERSION     DACDAF010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.022"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(10..288)
                     /locus_tag="IVZ69_000988"
     CDS             complement(10..288)
                     /locus_tag="IVZ69_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183093.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            481..1137
                     /locus_tag="IVZ69_000989"
     CDS             481..1137
                     /locus_tag="IVZ69_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP8183094.1"
                     /translation="MDSRVLKEYLDKNDFPIIRKGYHKYLTFEGMEDSHTYILKEGTV
                     KASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESEYAEFYRINRVRFW
                     QNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLYELYDLFGVRTEEG
                     MLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIVILNMDLLEDNIIF
                     "
     gene            complement(1579..2376)
                     /locus_tag="IVZ69_000990"
     CDS             complement(1579..2376)
                     /locus_tag="IVZ69_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HAP8183095.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(2373..3557)
                     /locus_tag="IVZ69_000991"
     CDS             complement(2373..3557)
                     /locus_tag="IVZ69_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP8183096.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(3582..4829)
                     /locus_tag="IVZ69_000992"
     CDS             complement(3582..4829)
                     /locus_tag="IVZ69_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virion core protein"
                     /protein_id="HAP8183097.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            5044..6789
                     /gene="dnaX"
                     /locus_tag="IVZ69_000993"
     CDS             5044..6789
                     /gene="dnaX"
                     /locus_tag="IVZ69_000993"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HAP8183098.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            6809..7123
                     /locus_tag="IVZ69_000994"
     CDS             6809..7123
                     /locus_tag="IVZ69_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HAP8183099.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            7148..7744
                     /gene="recR"
                     /locus_tag="IVZ69_000995"
     CDS             7148..7744
                     /gene="recR"
                     /locus_tag="IVZ69_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HAP8183100.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            7808..8452
                     /locus_tag="IVZ69_000996"
     CDS             7808..8452
                     /locus_tag="IVZ69_000996"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HAP8183101.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            8467..8796
                     /locus_tag="IVZ69_000997"
     CDS             8467..8796
                     /locus_tag="IVZ69_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183102.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            8810..9748
                     /gene="holB"
                     /locus_tag="IVZ69_000998"
     CDS             8810..9748
                     /gene="holB"
                     /locus_tag="IVZ69_000998"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HAP8183103.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            9784..10608
                     /locus_tag="IVZ69_000999"
     CDS             9784..10608
                     /locus_tag="IVZ69_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HAP8183104.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            10601..10948
                     /locus_tag="IVZ69_001000"
     CDS             10601..10948
                     /locus_tag="IVZ69_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HAP8183105.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            11017..11889
                     /gene="rsmI"
                     /locus_tag="IVZ69_001001"
     CDS             11017..11889
                     /gene="rsmI"
                     /locus_tag="IVZ69_001001"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HAP8183106.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            11998..13119
                     /gene="dinB"
                     /locus_tag="IVZ69_001002"
     CDS             11998..13119
                     /gene="dinB"
                     /locus_tag="IVZ69_001002"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HAP8183107.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(13173..13775)
                     /gene="nrdG"
                     /locus_tag="IVZ69_001003"
     CDS             complement(13173..13775)
                     /gene="nrdG"
                     /locus_tag="IVZ69_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HAP8183108.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(14090..16279)
                     /gene="nrdD"
                     /locus_tag="IVZ69_001004"
     CDS             complement(14090..16279)
                     /gene="nrdD"
                     /locus_tag="IVZ69_001004"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HAP8183109.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            16605..17372
                     /locus_tag="IVZ69_001005"
     CDS             16605..17372
                     /locus_tag="IVZ69_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183110.1"
                     /translation="MEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGEFVGIMGPSG
                     AGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQEFNLIDTLN
                     AKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQRIAAARALV
                     VQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTASYCDRILFIK
                     DGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            17362..19404
                     /locus_tag="IVZ69_001006"
     CDS             17362..19404
                     /locus_tag="IVZ69_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183111.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            19685..19834
                     /locus_tag="IVZ69_001007"
     CDS             19685..19834
                     /locus_tag="IVZ69_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HAP8183112.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            19845..21359
                     /gene="dltA"
                     /locus_tag="IVZ69_001008"
     CDS             19845..21359
                     /gene="dltA"
                     /locus_tag="IVZ69_001008"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HAP8183113.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            21356..22561
                     /gene="dltB"
                     /locus_tag="IVZ69_001009"
     CDS             21356..22561
                     /gene="dltB"
                     /locus_tag="IVZ69_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HAP8183114.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            22606..22839
                     /gene="dltC"
                     /locus_tag="IVZ69_001010"
     CDS             22606..22839
                     /gene="dltC"
                     /locus_tag="IVZ69_001010"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HAP8183115.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            22842..24110
                     /gene="dltD"
                     /locus_tag="IVZ69_001011"
     CDS             22842..24110
                     /gene="dltD"
                     /locus_tag="IVZ69_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HAP8183116.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            24251..25333
                     /locus_tag="IVZ69_001012"
     CDS             24251..25333
                     /locus_tag="IVZ69_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HAP8183117.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            25333..26136
                     /locus_tag="IVZ69_001013"
     CDS             25333..26136
                     /locus_tag="IVZ69_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP8183118.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            26206..26946
                     /locus_tag="IVZ69_001014"
     CDS             26206..26946
                     /locus_tag="IVZ69_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP8183119.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            26957..27961
                     /locus_tag="IVZ69_001015"
     CDS             26957..27961
                     /locus_tag="IVZ69_001015"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HAP8183120.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(28006..29703)
                     /locus_tag="IVZ69_001016"
     CDS             complement(28006..29703)
                     /locus_tag="IVZ69_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183121.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         9405 a         5235 c         6109 g         9010 t
ORIGIN      
        1 acattcccct taagctgaat atgcttttaa tttttgtatt tgaacttcta catcgtgata
       61 attggatgga tagcgatcaa caagttggcg aataaataaa tctcttgtag acataaacag
      121 atttaaaaat tcttcgcatt cgtttgttgg attctcatcc actgctttga tcaattcgat
      181 cgagttttga tacgcatcat ttaaaaagac taaagaagct ttcatatcaa atcttgtttg
      241 atatgctgtt tctaatcgat taatgattgt gttcatccag taattcatgt tttttccctc
      301 tattcttaaa aaattttact tctgcagtat aacgaataaa aaaaaggaaa aaaatcgcat
      361 aagtgatgga aaaaggtact taacaaatgt taatatcatt agtaaaatac ctttggactt
      421 taaaaagttt taaagtactg tatgatcttt ttagatgaaa gtttggatgg gggagcatca
      481 ttggatagta gagtcttaaa ggaatatttg gataaaaatg attttccgat tatacgcaaa
      541 ggatatcata aatatttgac attcgaaggg atggaagatt cccatacgta tatcttgaaa
      601 gagggaacgg taaaagcaag tgttatttca aatgatggga gagaatttaa ccttcgctat
      661 atcaaagatc ttgaaatcgt ctctctttta aaagacgaat attcacaatt catcgattcg
      721 ccgtataata ttcgagttga atcagaatat gcagagtttt atcgaatcaa tcgtgtgcgc
      781 ttttggcaaa atatcaacca agacccaaag ctacaacact atgtaaaaga gtattaccgc
      841 tatcgtctgc tttattcgat gaaaaaaatg cagcaaatgc tattaaacgg aaagctggga
      901 gctgtttgta cgcaacttta cgaattatat gatttattcg gtgtgcggac agaagaaggg
      961 atgctgatcg atttttcgat cacgaatgaa gaaatcgcca aattttgtgg catctcaact
     1021 gctagcagtg taaacagaat tttaaaacaa ctgaaaaaag atggtattat caccgttaaa
     1081 gaccatcata tcgttatttt gaatatggac ttgttagaag acaatattat cttttgatga
     1141 acaaagaggt tgtgaaatca gcgttttgac ctgagtatta gagaaacaaa cggaaaaata
     1201 gttcctcata ttttgccgtt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt
     1261 taccaagagg ttgtgagcct gccgtttaac tctgagtcac aaggaacaat ttcaaaaaac
     1321 agcttttcat gtttgatgaa tattgtgact tgtgaccgag gagttggtag gagaacaccg
     1381 tttaccaaga ggttgtgaaa aagctgttct gcatcaagta ataagaagag ccaagtaaaa
     1441 acagtctctt atgtttttaa cttggctgga cttatcaccg tagatgtaag cttttgaacg
     1501 ccgtttattt gcaacaaaag gggctgtgac acgatttttg tcacagccct ttttttgcga
     1561 acattcattt agcaattttt agaaacttct gccgccaccg ccaaaagtcc cgccaccgct
     1621 agaatgggta gtacttccgc caccgccgct tccaggaggt gggcttttgg ggattcttct
     1681 tgtcgtgaca aaagaatttg tcagacgatc ggttttttca gttaatttga tactggattt
     1741 ttctcggaat ggatatttgt agatgcctga tttcaattga taacgcgaaa cagtcacaaa
     1801 ataaaagaca agactaagga taagagccaa aacaacagca atgatgattt ctactgtcgt
     1861 caaaacctta tagcgtgtaa ttttgccagt ttcttcgtct acacgataat gtcctcctgg
     1921 aactccgtct tccacatatg ttgctgattt agacaggtaa gcttttgcag cattgtaata
     1981 ggcagcattt gtcatctgat cataaacatc atctaagatc gaatcgattc tgctatcagt
     2041 caaataatcg atcatattac cagaagtcga aatgtagatt tcacgctgtc ccatatctaa
     2101 tagcaatact gagccatttt gatcatttcc gactgcgtct cttaagtaat tatcagcaaa
     2161 gtctcttggt tcttctgaat tagatgtagt cgttacgatc aagactcgtc ctttgatttt
     2221 ttcattcagc ttttctgcct gttgttccaa agattggatt tgatctgttg tgaataaccc
     2281 agcctcatca tttaccgtag ctgtatctgc atgagtagcc accggccagc caacacttac
     2341 tagcaaaaga aagaataaaa aaaatttttt catcatatca agtaacctcc gatcagaaag
     2401 aggatcgcta gcccagcgaa aatcccaaga gcggtcagtc ccaatttttt ctggctgatc
     2461 ggcaggacac cgctgacctt tcctgtttgt ccattcattg cgtagtagta gactttttta
     2521 cttgagtcat tgcttcgata agtaacaagc cataccggca gtaatacgta attatttact
     2581 tcgtttgtga ttgaagcaga agttcgcaca ccggtcaatg ttgtatatcc atttgcggta
     2641 tcttttaaca gcttctctga atagtctttt aattcagatt gaatctgtga tttgattgcc
     2701 tcatattcga tatctctttt ttctgcttgg aacccggcta aatactggct tttaaaatca
     2761 attgctttat ctaacgggaa aggttgcacg ccttcgacca tcttttgttg cgtatttttt
     2821 gataaggcat tttttactag ttctttaaaa gaaagcttgc ctgctcttga aacagcaaat
     2881 tgcttcgttt ctgtgtattc gatgtcacct atccgccata tgcggataac tgtaccattc
     2941 gcctgcatgg caccatctac ttcagcatct gtagcccaat aagggaaata cacacctgtc
     3001 aacttatcga tttgatcctt attgaaaaaa gctttgggaa caaaccattt tttcttggtc
     3061 caagcgagaa atctgttgat tgcttcttct ttctcgacag caaaaggaag tactttattt
     3121 ggcaagaatt ctccgcttaa acgtcccgat agtacgacgg gattatggca gtagtaacaa
     3181 taagtcgcag cagttgtcgc atcagtcacg atctctgcac cacagttggg acaaagaaaa
     3241 agatctatcg ctgcggtatt atctgcagat tcgtccgctg tatctgaaaa accgcctgcc
     3301 tcgtcaaccg ctttgcgctc ggcttcattc atatcggcaa gctgttcttg ggctgtaaaa
     3361 gtaaaatctt cggtaggtga aggttcttct ttgctttctt cgccagccat acgcgcttct
     3421 ttttgctttt gctcatattg gctgacttct tcttctgtat agatattcag gcagtattcg
     3481 caatgaaatt tttggtcttt gggatcaaaa gtcaacggac cgccgcaatt aggacattta
     3541 tgtgtaagaa catccatcag ctgcacacct ttctaaataa attaattaac ggggattcct
     3601 ttaaacggtt taccacagtt tggacagaat ttagggatgc cgttggaaag atccacgatc
     3661 tcattgcatt cactgcatcg catttgtagc ttaggctgaa cgttttctac aggtttggca
     3721 gctccgcagt tggaacagaa ttttccggaa ttttctgtcc cgcaaactgg acatgtccaa
     3781 gtatccgcat ttccttgtgc agtttgttga ttttgttttt ctgcttgttg tttgatttgt
     3841 tcttggttat tttgagctgc ttgagaaaga taagaaccat ttgcattcat tcccatacct
     3901 acacccataa agccggtcat tgctcctgct tcattttttc cggctgcttc cataccacgt
     3961 gcaatggaac cttgcacgta tccttcacgt acgctaggat cacctagcat cgccccttcg
     4021 ttacgcatat tgatcagttt cacagaatca tcggtgtaag aaatgctggc tacagccaca
     4081 gaaacaatct ccatcccacg taattcacgc caagaatcat ccaatgcagt atccatgtat
     4141 ttgcttaatt ccaaactctt agatggtaca taagaaatcc gttgaccatc tgcagacatc
     4201 tgattgattg ctgattgtag cgctgttagg aattcagcta aatactgctc attgatatca
     4261 ttgatttcca cttgtgtttt gtttttaggg attgcgtttg tataaaataa aatcgggtca
     4321 acgacatgaa tagaataagt gccatgtgcc cgtaagaata attctgcgtt atagaaattg
     4381 tcaaagtagt tcaacggcgc gcttgtaccg aatttgattc cctttatttc ttggagattg
     4441 atataaaaaa cttgttgttt ctgcggtgtg acgccgccaa atttgaatcg gtcaaaagtt
     4501 tcagcaattg cttctttcag tgttccattg aacatggaag gagctgcgtc atttttaatg
     4561 gtgtaataac cttcctcagc ggtataatcg atgatttttc caccatcgac caaaagcatc
     4621 atcatgtttg gatagacatg gacgactgtt ccgtctgtta aaacatcttc tgttccttta
     4681 cgattggagc cacgtttgtc atctttgcgg actttgacac cttttgtcat gaccgttgta
     4741 tcactcatat tgtctggttc gatgacttct agccattgat ctgccagacc gccgccaacc
     4801 atacttgttg ctgctttgat aagacccata aaaaattcct cctctgattc agctagtgcc
     4861 aaacaattat tgtttattta ttataccata ggaagatgtg aaacttctcg gactagagac
     4921 ggaattgaaa tggaaaattg cgtattgttt aaatacctga aaaagccgag aaggatagta
     4981 gtttttttac ctaatatcac gtataataag agatagtgaa ttttttaaaa aagggggatc
     5041 cttatggcat atcaagcact ttatcgagtc tggcgttcgc agcgtttcga agacatcgtt
     5101 ggacaaaaag ctgtgacaca gacactaaaa aatgctattg tttcccacaa aacctcacat
     5161 gcctacttgt ttacaggacc cagaggaacc ggaaagacga gtgcagcaaa gattttcgca
     5221 aaagcaatca actgtccgaa cagtaaagac ggtgagccat gcaacgaatg cgaaatgtgt
     5281 cgatcaatta ctgctggtac gcaagaagat gtgatcgaaa tcgatgctgc cagcaataac
     5341 ggagtcgaag aaatccgatt tatccgtgat cgggcaaatt atgcgcctac aaaggcagcg
     5401 tacaaagtgt acattattga tgaggtacat atgctttcaa caggagcttt caatgccttg
     5461 ttgaaaacat tggaagagcc aaaagaaagt gtcatattca tcttagcaac gaccgaacct
     5521 cacaaaatac cagctacgat catttcacgg actcagcgat ttgattttaa acggatcaat
     5581 acggcagata ttgtcgaaca tcttgaattt atcttgaaag aatcgactat cagctatgaa
     5641 ccagctgcat tgaatgtgat tgcccgttct gcagaaggcg ggatgcggga tgcattgagt
     5701 attcttgatc aggcaatctc gtttagtgaa ggaacaatta ctttagatga tgccatgcaa
     5761 gtgacaggta gcttaactga cgaaatgatg gacagttact tgagtgcttg cgtgaaaaaa
     5821 gaagtaccag aagcattgga aacattgaac caaattctcg cagccggcaa agaatcacgt
     5881 cgctttctag aggatatgtt acaatactgc cgtgacttgc tgatgtatca gcaagcacct
     5941 aacctagttg aggaacaatc gagtacgatc agaagtacat ttacagaatt ggcacaaact
     6001 gtttcagcgg atcagctgtt ttcaatgata aagattttga gcgatactca aaatgaaatt
     6061 cgttttacca atagtgccgc tatttatttg gaagtcgcta cagtcaaact tgcacagcta
     6121 ccgtctgctt ctgttccttc agcagatgta gcatttgcag atgatcagat agtaaaacag
     6181 ctacaacaag agattaagga actaagaaac gaaatcaagg aactacgcag taatacagga
     6241 attgagaata caaaagtaca gccggtacag caaacaaatc ataaaaaaca gacaagtacc
     6301 tatcgtgtac cgacggaacg agtatataaa gttctgcggg aagcgacaag acagcatctg
     6361 aaccaagtaa aagaagtatg ggaagacttg ctgatgagtc tatctgtcac tcagcgagca
     6421 atgcttaaag caagcgaacc agttgcagct ggacctacag gactagtgat tgcgtttgat
     6481 tatgagattg tttgtcaaag agcagcaaat gacgaagaat tgcagctttc ggtacacaac
     6541 aacttaagcc gaatgatcaa agattatgcg cctgatcctg tttatattac aagagaaagc
     6601 tggccagaac ttcgaagaaa ttatttgacg caggcacaag aagagggaac agaaaactct
     6661 tttgcttctg aagactcaga aggagaaatc gagttgcttc ctcaagaaca agaagtacca
     6721 gaagaaacac ttgtagtaaa agcagaggaa ctgtttggct ccgaagctgt tacagtggta
     6781 gatgattaat aaaaaggagt agataattat gatgcgtgga atgggcaata tgcaaggcat
     6841 gatgaaacaa gtacaaaaaa tgcaaaaaga aatggcagaa gcacaagagc tgctaaataa
     6901 aacagagttt acaggtaaag ccaccaatga attggtcaaa gcggttttta caggcgatcg
     6961 tcgcatgaaa gatatccaaa tcaatgaaga agtcgttgat cctgatgata tcgagatgct
     7021 tcaggatctt gtcgtaatgg cagtcaatga tgcgatcgca caaattgatg tggaaactga
     7081 gaaaaaatta gggaaatacg caaaaggttt gccaggattt tagttttaaa ctgaaggagt
     7141 aatgaatatg caatatccag aaccaattgc gaaactgatc gacagctaca tgaaacttcc
     7201 aggaatcggt cagaaaacag cgacaagact cgccttttat acgatcgata tgaaagatga
     7261 agtagtaaat gaatttgcta aatctttgtt aagtgtaaaa cgcgatttgc atttttgtag
     7321 tatctgcgga aacatcacag aagaagatcc ctgcgaaata tgtagaaatc cttcacgtga
     7381 tcgaagcgtt atcctagtgg tcgaagagcc gaaagatgta atggcaatgg aaaaaatgcg
     7441 agaatatcac ggactttatc atgttctcca tggtgtgtta tcaccgatgg aagggacagg
     7501 tccagaagac atcaatattt cttctctgtt gcagcggctg catgatgcag atgtaaaaga
     7561 agtgattatc gcaacaaatg caacaacaga gggagaagca acagctatgt atctctcacg
     7621 tctgatcaaa cccgcaggta tcaaagtgac tcgtctagca catggtctgt ctgtaggctc
     7681 tgatatcgag tatgcagatg aagttacttt attgaaagct gtcgaaggaa gacgtgagtt
     7741 ataaatttct aattaagtgt tttttcagat acaatataaa agcagcacaa gagatggggg
     7801 caacaatgtg aacggactat ttattacaat cgaggggcct gatggtgcag gaaaaaccag
     7861 catcttgaat gaactttacc ctcttttgaa agaagtagca aaaacagaaa tcattcaaac
     7921 aagagaacca ggaggcattc cgattgctga agagatccga gcagtgatcc ttgatccaaa
     7981 aaatgatcgg atggatgaac gtacggaagc actgctttat gcagcagcaa gaagacaaca
     8041 tctagtcgaa aaggttctgc ctgctctggc aaaagggaaa atcgttttat gcgatagatt
     8101 tgtcgacagt tctcttgctt atcaaggtgc aggccgacgc atcggcgtta ccgagattgc
     8161 tcggttgaat gagtttgcta cagaaggtac tacgccggat tttacccttt atcttgacgt
     8221 agattcagac accggattaa gaagaatcaa gaaaaacaga caaaatcaaa tcgaccgttt
     8281 agattcggaa ggtttggaat tccaccagcg tgtacgtcat gcttacttaa agctggcaga
     8341 agagaatccg gaaagaatcc acaaagttga tgcaagaaaa agctttgaag aagtgctgca
     8401 aacaagttat catacaatta ttgaacagta tccgcaattt tttgaaaact aggaaggtga
     8461 acgtttatga aaattatttt agcgattatc caagacaaag acagcaaccg tttatcaaat
     8521 gaattgattg atgcaaatat ccgtgccaca aaactatcat cgacaggcgg cttccttaag
     8581 gctggaaaca gtacgtttat cgtgggtatt gaagatgacc gtgtagaaga agcattggaa
     8641 atcatcaaaa aaacgtgtga atcaagaaag caatttgtat ctacacctgt tacactggat
     8701 atttcgatgg atgggggcgt cccttatcca gtagaagtag aagtaggcgg tgccacagtc
     8761 ttcgtcttac ctgttgaagg attccatcaa ttttaggagg agctgagcta tgaatcaaga
     8821 aataaacttg gctcaaatgc aaccgatcgt gtatcagcag cttcaacgga gttttgagca
     8881 tgggcgtatc gctcatgctt atctttttga aggggagaaa ggaacaggaa aacatgaagt
     8941 aggtatatgg cttgcacagc acctgttctg tacccaaatg aaagacaatc tgccttgtgg
     9001 aaaatgcaac aattgtcagc ggatcgaaaa gaaagaacat ccagatgttt tggttattga
     9061 accggaagga caaaccatca aagtcgatca gatcagacgt ttgcagacgg aattcagtcg
     9121 cagcggttac gaatcaagaa aaaaagtttt tttgatcaaa gaagctgaaa aaatgaatag
     9181 cagtgcggca aacagtttgt tgaaattctt ggaagagccc cctggagatt ttttagcggt
     9241 gttagaaaca gatgcagtag gaagaattct ccctactatt caatctcgtt gtcaagttct
     9301 gcattttcaa gaactttcga aagaagcact gatccatcga ttgcaagaag agcagattcc
     9361 attggaaaaa gcaaaacttt tggctttctt aacaaacagt ttaggaaaag cagttgaaat
     9421 ctctcaagat gaatggttta atgatgctaa ggacttgatt tatcaatggt tcgtttactt
     9481 gcaaaagcaa gatactcaag cctttatcta tgtccaaaaa aaattggtaa aatcatttaa
     9541 agaaaaaaca caacagttta caggattatc tgtcttgatg ttttattatc aggaagcaca
     9601 gcgtcaagca gtagcaaacg gcgaatatgg caaagtgaaa cagataaacc agataattga
     9661 acggatattg atcgcagagc agaaactacg cagcaatgtc agttttcagg ctgttgcgga
     9721 acagttcgtt ttgcatacga ttttttagct tgccgcaaag gatgatgatc aaggaggatg
     9781 gaaatggtag aagtagtagg tgtccgatat agagatgcag gtcatatcta ttattttgca
     9841 ccaggagact ctgaatatgt ttatagtgac aaggtattag tcgaatctca gcaatcctta
     9901 catattgcta ctgttgtcct tcctaaaaaa gagattgatc ccaatgacct tcctgaagct
     9961 atccgtccga tcttgcataa agcgtcacaa gctgaattag aaaaagacaa aaaaaacaaa
    10021 aaagatgctt atgatgcatt gaaaatcgca aaagaaaaag tgcagttgcg tgagttggaa
    10081 atgaaaatgg tcaaagccga atacacattt gatcgaaata aattgatttt ttctttcaca
    10141 gcggacgggc gaattgactt tagagaattg gtaaaagatc tggccgctgt atttcgtact
    10201 cgtattgagc ttcgacaaat tggtgtccgc gatgaagcaa agataatagg cggaattggt
    10261 ccatgtgggc gtccattatg ctgttcttct tttttaggcg atttcgtgcc tgtatcaatc
    10321 aaaatggcaa aagatcaaag tttatctttg aatccaacaa aaatttccgg tttatgcgga
    10381 cgcttgatgt gctgtctgca atatgagagc gaagaatacg agacagcgaa aaaagaactc
    10441 cctgactttg gaaaagtaat tgctacacct gatggtaaag ggaaagtcgt agggttgaat
    10501 ctgcttagcc gtatcgttag tattcggctg actggacggg aaaatcctgt cgaatatgaa
    10561 tgggatgaat tgaaagaatt tatccaagta ggtgagatga atggataaga gatcattata
    10621 cgacggattg aatcaattag aatcagagtt gagaaataca ttaacagaac ttgttgaaat
    10681 gaagcatgct ttgcatgaga tcgtagaaaa aaatacaact ttggagatgg aaaatcaacg
    10741 tctgcgggaa cacctgcggg aattgaacca agttgcacaa gctccagctg aaaatgtgaa
    10801 gcaggaactt tctaagtctc gtatgaatct tgaaaaaatt tatgaagaag gattccatgt
    10861 ctgctacgat ttatatggat caagaaggga caatgacgag ccttgtgcgt tttgtctaga
    10921 agtgatctat cgcgaaagcg gtcgatgacc aataacaaga ggagactgga gcggagaaat
    10981 actgctccag tctttttatt aaggagattg tgacagatgt ataatcaaaa aagtttcaag
    11041 ggaaatccgg tatatgggga tttatatctt gtaccgacgc caattggaaa tttagaagat
    11101 atgagctaca gaagtgttcg tatgctgcaa gaatccgatc ttatcgcaag tgaggatacg
    11161 cgtaatacac aaaagttatt gaatcatttt gaaatccata caccccaaaa aagtttacat
    11221 gaacataatt ataaagaacg tgtccctcaa ttgattgctt tgttaaaaga aggaaaaacg
    11281 attgctcaag tcagtgacgc aggaatgcct tccatcagcg atcctggaca tgagctagtt
    11341 ttagcctgca taaaagaagg gatttctgtg atctctatcc caggacctac agctgggatg
    11401 acggctttga ttgcttcagg gctagtgcct caaccatttt tattttatgg cttccttcca
    11461 cgtaagaaaa aagaacagaa agaaacattg aaaaagctaa aagaacagac agttacgctg
    11521 attttttatg agtcacctta tcggatcact gctacattga cgaatttctt agaaattttt
    11581 ggaaatcgcc aagtcgtttt gtgtcgggaa ttgacaaagg tccatgaaga ataccttaga
    11641 ggaagtacgg aagagctact cgcttatatc gaagaacatc cagtaaaggg tgaatgttgt
    11701 ctgcttgtag aagggaattt gttcgaaatg ccagtgacgg aagttgatga agagttggga
    11761 acgttaaagg aacaagtaga agcaaagatc gcttcaggcg aaaaaccaaa tgctgctatc
    11821 aaagcagtag cgctgaaaaa tgggctgaaa aaacaagaag tctaccgtca gtaccatgaa
    11881 ttagactgag atagtataag ttgtctataa tgaaagacta atgaggaaat cagctactaa
    11941 cttttcaaat ctcttgaacg cgaacgaatg ttcttgtata atgaataaga ggtgaggatg
    12001 atggagctgc aatttccttt acataatgat acatcaagaa aaatcattca tattgatatg
    12061 gatgcttttt tcgcttcggt tgaagaacga gatcatcctg agtttcgcgg acatccatta
    12121 gtaattgcca gacaccccag tgacactggt gggcgtggag tagtgactac agcaaattat
    12181 gaagcaagaa aattcggaat tcattcagca atgagtgcac aaaaagcgta tgagctttgt
    12241 ccgcaagcca tctttaagcc tggcgaccat cataaataca gcgatatttc caaacaagta
    12301 cgggaagtat tctatcgtta tacagatatt gtggaaccag ttagtatcga tgaagcgtat
    12361 cttgatgtga ccgaaaataa aatcaattgc aagtcagcca tcaaaatcgc ccgaatgatc
    12421 caagcagata tttgggagag tgtccagcta acatgttctg cgggagtaag ttacaataag
    12481 tttttggcca aattagcatc agactatcaa aaacctagag gaatcacggt agttgcccct
    12541 caagacgctg tgccattttt aaaagctttg ccaattgaaa aatttcatgg ggtagggaag
    12601 aaaactgtac ctagaatgca tgagctaggg atttatacag gaaaagacct atatgaatgc
    12661 acagaaatga tgttgattcg aaattttgga aaaatgggct attctcttta tcgtaaagtc
    12721 agaggaatcc atgattctcc agtaaacgtt acaagagagc gaaaatctgt gggaaaagag
    12781 catacttatg ggcagccgtt gcaaacggaa gaagcagtgc tgactcagtt gcgccaacta
    12841 gctgaaaaag tagaagaagc actgagaaga gtccaaaaac atgggaaaac agtagttttg
    12901 aaggtcaggt acacggacta ttctactgtg accaaaagag tgacattgcc agaatatatc
    12961 tataaaaaag aagcactctt ttatcaagca agccttatat gggaggaaat cttgggagta
    13021 gaaaaaggaa tccgattgtt agggattact ttgacgaatc tggacccgat gacttatgaa
    13081 aacatcgtcc ttccattatg ggaaaatcaa gaaatataaa aacagctttg agagttgaaa
    13141 ccggaaatcc gttttctctc ccaaagctgt ttttatatca agtcttgctt tttgatttgt
    13201 tcataggttt ctgttgcatc cgtacatttt tcccaaatca caacttgatt ggattctaaa
    13261 gatttttgga cgtcaatgat ccgctggttg ctacttccgc gaaattgtag ttttaggtca
    13321 cgtttgctta attcaaagcg tccgtcaaca aggatatcga tttgcgaaag gagttctaat
    13381 ttatcttctg aatcttgtag caattcatca aaggtatagc ctgtccatga ccagatatct
    13441 tttgtcgtac cgaactcttt tcggatacgt cgtacgactt gcagacaaac atctgtattc
    13501 aaaaaaggtt cgccaccaag taaagttaat ccttgcacgt aatcgttgcg caagtcagcg
    13561 atgatttgtt cttctaattc aggtgtgaat ggtttgccat atcggaaatt ttgtgcagct
    13621 ttgttgaagc agccttcgca ggcaaataag cagccactaa cgtaaagact gttgcggaca
    13681 ccttcaccat cgacaaaatt aaacggtttg tagtcagcaa tatagttttg gctgtagtct
    13741 tttgctaacc attcttttgg ttttggattt ctcataaaaa aacttctttc atttaaggtt
    13801 caaagatata gctattgaag ataaaatcta ctcgaccaca taaataagaa caaactgacc
    13861 taaatccatt gttcaagaaa gcttgttctt attttgatag agggcgttca aagatacaaa
    13921 gccatcgaaa gagggtggtg aaaaaagact tgtcatagcc tcttattctg aataaacggt
    13981 gttcaaaagc ttgcatctgc agtaataagc ccaactaaac gaaaaatatg aggaactatt
    14041 tttgtttagc tattcttatt acttgatgca ggacagcttt ttcacaacct catttcatgt
    14101 gtttcacacg tgaggaaatt tctttatggc ggccatgtac catcggacga gcttgcggat
    14161 ttcctaaata gccacaagta cgtttgacta catcacatgt ttttggatca tgatttccac
    14221 attctggaca ttcgaaccct cgttctgtcg gtttgaaatc accttcgaaa ccacattgat
    14281 agcaatgatc gattggcgta ttcgtaccaa gatacccgat tttgtcatat gcaaaatccc
    14341 atacagcttc taaagctttc ggattttgtt ggagcatagg gtattcacag tagtggatga
    14401 atccacctga acaatatttt ggataatcct tctcaaattc caatttttca aatggcgttg
    14461 ggtttttacg cacatcatag tggaaactgt ttgtataata ttctttatct gtgatatttt
    14521 cgatgatgcc gaatttttct gtatccaaac ggcagaaacg gtcagttaga ctttcacttg
    14581 gagttgaata gacactgaaa tgataaccat attcatcccc ccatgcatct gcattagctt
    14641 ttaattcttt gacgatatca agtgtgaaag cttttgcttc tgggtttgtt tcccattcgc
    14701 caccgaagaa agctgaagca acttcataca atccaatgta gcctaacgat acagtagctc
    14761 gacggttttt gaataattca ttgacagaat cggtacgtga aagacgtttc ccgaaagcac
    14821 catacatata taaaattggc gcatttgctg gaatggcttc tttacaacgt tctacacgat
    14881 agagaagcgc atctttcatg atttctaagc ggtcagacag taactgccag aatttattct
    14941 gatctccttt tgattcgatc gcgattcttg gcaaattcaa tgtaacaaca cctaaattca
    15001 ttcgtccgac atttacttct tgaccatttt cgtctttcca cccttgcaag aatgaacgac
    15061 agcccatagg tactttgaaa cttccagtta attcaacgat tttatcgtaa ttcagaatat
    15121 caggatacat tcttttcgtt gcacattcca atgctagttg tttgatgtcg taattaggat
    15181 cttcagggtt taagttcaca ccttttttca aagtgaagat cagtttaggg aagatagctg
    15241 tccgcttttc actccctaat ccattgattc gaatctgtaa aattgctttt tgaatttctc
    15301 tttcaaacca gttttctcct agtccaaatc ctaatgaagt gaaaggagtt tgtccatttg
    15361 aagtaaataa ggtattgatt tcatattcca aactttgcat agcatcgaag atatcttttt
    15421 tggtttttgc ttttgcatat tctttttggc gttctggcga atcgatccat tcttccgcgt
    15481 cttttagatg ttttttatag ttcaattctg caaaaggagc aagcaattca tctgttcggt
    15541 cggcagaaca gccaccatat tgacttgacg ctacattggc aataatctgt gagatttgtg
    15601 ctgtggcggt ctggatagat tttggcgatt cgacttcggc attgccgatt ttgaacccat
    15661 tgttcagcat gcctttgaaa tcaatcaagc agcaattcgt catcggtgta taaggatgat
    15721 aatccaaatc atggtaatgg atatcgcctt tttgatgcgc atttgctata tgtggtggca
    15781 acattttcag tccgattgat tttccaacga tcccggctgt cagatctcgc tgtgtattga
    15841 aaacattact gtctttattt gcgttttcgt tcacgacagt ttggtccttg ttgattagct
    15901 tttcaatcga aaagttgata tctgttgctt tactgcgagc aaaatctcgt ttggtacgat
    15961 aattgatgta ctcttctgct aattcatatt cgtttttttc tagtaatata tgttccacga
    16021 tgttttgaat ctcatagatt ttgacatttt cagcaaaccg gcttttgatt tcttggacaa
    16081 ccaagtctgc aatcatttga attttttcat aagtaagtgg tgataatgag ccgtgaattt
    16141 tcttttctgc tttgatcagt gcttcattga tcttttgttc atcgaaatca acatggcggc
    16201 catcgcgttt gatgactttc atctgggatg tctctggctg ctgagtaacg acagtttttt
    16261 cttcataatt tactttcatt atcttcaact cctgctaaat tgttcttgtc tatcataaaa
    16321 caaaatcggg gaaggagcaa ctaaatatcg gctatatata gtattcaatg tgctgtataa
    16381 ttggatttct atactatatg tagtgtatat tttattgtga aaaaaggtga aaacttgtag
    16441 ctggtggatt tgttttttgc atatttaatt ttgctgaata aaataattga ataaaatttt
    16501 ttattcagtc caagtaaaag tgacaaaaac ataagagcaa attattcgta gatatgctac
    16561 tatgcaaata aatagaaatg aaaaatgaaa gaggaggaga agaattggaa aagatgatcg
    16621 aagtgaaaca tctaagtaaa agctacggca gcaaactttc tcccgtcaaa gccttagata
    16681 atatctcatt cacagtagaa gaaggcgagt ttgttgggat tatgggccca agtggtgcag
    16741 gaaagacaac gctgatgaat atcttgtcca cgatcaattt gcctacgatg ggcagtgtct
    16801 cgatccaagg aaaagaaatc acaaaaatga aaaacagtga gctcagtgac tttcgtcgaa
    16861 aaaaactagg attcattttt caagagttca atttgatcga taccctaaat gcaaaagaca
    16921 atatcctatt gcccctagca gttgaacgga tgactaaaga ggaaatggaa aagagagtaa
    16981 gacatgtagc tcaattgttg aatatagaag aactgctcaa acggtatccc gatgaacttt
    17041 ctgtcggaca gagacaacga attgcagctg ctagagcact tgttgttcag ccacaagtga
    17101 tttttgcaga tgaaccaact ggctctttgg actcgaagtc ggctacagaa ttgttgaact
    17161 acttgaagac catgaatcaa aaagaaaaag caacgatact gttagtcacc catgatccat
    17221 atacagcaag ctactgcgat agaattttat ttattaaaga tggtgtgatt ttttctgaag
    17281 ttgtcagaag agggacaaga agagagttct ttgagaaagt aatagacatg caggcgacga
    17341 ttggcggagg aggaaaaatg aatgctgtat aaactagccg ttaaaagttt ttttcggcag
    17401 tcacgaggct atcttgttta ttttttcagt ttgactttat ccgtaatgat ctattattcc
    17461 ttcagcgcaa tgacctacga tcaatcttta gtcagaagag caagtcaaga tacttcgata
    17521 gatggtggat tgagttttgg tggatttatc attactgttg ttttgctttt tttcgtattc
    17581 agtgccaacc gatttttctt gaatagaagg caaaaggaaa taggcatcta tcagcttttt
    17641 ggtatgaata aactgcagat atcaggtata tatgtgttag aaatcatgat aattggattg
    17701 ttcgcctgta tttctgggat attactcggt attatttttt ccaaactctt ttcaatgatt
    17761 ttggttcgaa tgatggatat ggatcttact agtccatttt ttatctccat tccatcagta
    17821 gtagatactt tatttgcttt tttcatcatc cttttagcag tatctgtata ttcaatatgg
    17881 aaaatatggc gctatccaat gattcgaagt tttggagaaa aagaacaagc agatagttca
    17941 acaatgcgct tcaggacaag gcaccgatta ctcgcagtca tcgggttact acttttaacg
    18001 agcggatatt ttggagctag tcattttagg gaaatcactt catggatgat cagttatcat
    18061 tatcttgata cattagtttt cttttttcct tttttaattt ttttcgtttg tgtggtcggt
    18121 acttatttgt ttttctgtta tacatttcgg ttatttttga tcatattgag taaatggaag
    18181 atttattact atggtatcaa ttttttgata atgggtaaca cgcaagttca tttgctcaaa
    18241 agttggcgta caaattctct gattacagtc attctcggaa tttctttaat gacaattggc
    18301 ggcacggcta gtatctctac tattttatcc taccaggaga aagtttcctc cccgatggac
    18361 tatcagtttg atgttgagac agagaaaaaa atcaagccga ttctagcaga ggaagggcag
    18421 aagataacta aagaaatcac cttgcattat aaagtcattg ggagtatcta tagtcaaaat
    18481 ctcgaagaac ctatgtttca aactgctaat ctgatcacgg aaacacaata tcaagccttc
    18541 agaaaagtta atccagattt gccgaacatt tctttgaaat cacctggtca tactgttttg
    18601 cttgatcaaa tgcaaactct ttttcggaat atttcattat atggatctag tattggactg
    18661 ccagataatc aagaattgaa gattcaacaa atgcttccaa gtgtattagg tgacgaaaca
    18721 atggtatatc taagtcctgt actgattgta gatgataccg tttttgaaaa agcaaaaggt
    18781 gtggattatc aagtagtcaa tgtagatgta tcaggtggaa ataatgaaaa aatagatgaa
    18841 cgactgagca atgacctgtc gataaagtgg ctcaatgctg tttattattc ttatgatatc
    18901 gtaaatggaa gtctacaagg agaaattagc acaaagaaac ttccggatga ccaaatgaag
    18961 gaagcacaat ttagccaaga aagctctcgt ttgaatttct cttccagcta ttcgaaattg
    19021 cgtgcagtta atcggcgaat cggtatcaat atttttgtca cactatttgt cgggatgatc
    19081 gtgattattg ctactggtag tattttgaca gtccggcaat tagcagaagc agaggaagaa
    19141 aaagaaaatt atcacctatt gactaagctg gggattccac aaagaaggat cagacggatg
    19201 atcttcgagc aaaacgcact taccttcttt ccacccatga tattagggat cactcacgca
    19261 gtatttgcaa tcaatgtctt cactcagtat ataaaaactg ccgattactg gttggcttat
    19321 cttgtgagtg gcttattgat ccttatctat cttttgcttt atgtcattac gagtcagtta
    19381 tattgtcgga ttatcgagga atgatatacg gaataagaca agataataaa tagaactaaa
    19441 ttttgaatac catttatttg gaataagagg ttgtgacacg atttttgtca caacctcttt
    19501 attttttata ttttttaaaa gtacgagaaa ttataaagaa aaaagcagtg atttgatgtg
    19561 ctatttttat aaaagctatg tgacaaaact gttagtaaaa aaacggtttc tgtaagctag
    19621 acacatgttt ctttttgtca aaattagtta cactttgtgt gaggttatat gaggagggaa
    19681 tccaatgaac aaatggcgtt ctaatccaaa attgaattat tggggaaaat tcatcattcg
    19741 aacaattttt tatagtgcag tactgctgtt cctgatttat ctgtatcact ataaaaatat
    19801 tcaaggagga acttttatct ataacgaatt ttaggaggaa gagtatggaa atcaaaacga
    19861 ttattgaagc aatcgatgat tggggaataa atgaacctga tcgagttgct tatcaggcgg
    19921 atgagacgca tacttttggt gaattgaaac aagcatcaga cgcacttgct tattatttag
    19981 aaaaaaaggt agaaggcgat ggaccaattg tcgtttttgg caatttggag tttgaaatga
    20041 ttgtctcatt tctaggggtt gtcaaatctg gccatgccta tttgccgatt gaagagcata
    20101 cacccaagga gcgtatccta tcgatctttc gggtggctaa accatctatg gtcatcagta
    20161 tcggggactg gatagaagat attccttcgg ttcctgtcat aacaaaaaaa gaatttcaag
    20221 aaatcaagaa gataccagta ggattttatc ccagaaatag cgtaaaaggt acagaaaatt
    20281 tttatattat ttttacttct ggtactactg gagaaccaaa aggcgtacaa atcagtcatg
    20341 ataatctagt cagctttgtt caatggacga tggaagactt tgggatcaag cctggtatgc
    20401 atttcttagc ccaagcgcca ttttcttttg atttatcggt attttctatt tatcctgcat
    20461 tagtttctgg cggaatgctg aagccgttaa ataaagcagt tgttcaagac tttcgtcaat
    20521 tattcgcgac attgccagcc ttgaagttga atgtgtgggt ttctactcca tcatttatgg
    20581 atatttgctt gatggaacct acattcaatg gagaaaatgt gccggaattg gacatgtttt
    20641 tattttgcgg agaagaattg acgaaaaaaa ctgcagaaag tctacttgat cgattcccaa
    20701 atgcacggat atataatact tacggtccaa cagaagcaac tgtagctatt tcaagtattc
    20761 agattgacca gcatgtacta gatagttatg accgactacc gattggctac gtaaaaaaag
    20821 acacgaaagt ttctattgtc caagaaggta aacctgtttc aaaaggagaa acgggtgaaa
    20881 tcattattgc aggaccaagc gtatcaaaag gttacctgaa caatcccgaa aagacagctg
    20941 ctgcgttctt ttgtcaaaat gacttagcaa gttaccatac aggggatgca ggtagactag
    21001 atgaatatgg gcttttattt tatgaaggac gtatggatca gcaggtcaaa ttacatggat
    21061 accggattga actcggggat atcgaacatt atctgctcca agacaaccga atcaaacaag
    21121 ctgtcgtcgt accaaaatac caaggaacaa aagtacagca gctggttgct tttgtcgtat
    21181 tagaaaacaa aacgaaacag ccggattttc agttgactaa atctatcaaa gaacaattac
    21241 tagaagttgt aatggattat atgattcctc agaagttcca ttatgtcgat ctgctgcctc
    21301 agacagttaa tggaaaaatc gatcgaaaaa aattaacagc tgaggtgaat cctgaatgat
    21361 gttacctcat atgatccctt atgcagagcc gttttatttt tttcttttag ccattgcgct
    21421 tgtaccgatc gttctatctt tattgatatg ggaaaaaaga ttaccagttt atcaatcagc
    21481 agtgacactt ttctttttat ttgtcagctt tggaggtaat tattggcaac agggagcggc
    21541 gctgattggg tatgttttgt ggcagacgat acttgtatgg ggctattttg tttatcggca
    21601 aaggaaaaat cagacaggat ggttttttgc cgccgttatt ttagcgataa ttccactgtt
    21661 tttaacgaaa gtgactcctt tttttgaaca tggaaaagca tcgttacttg gttttttagg
    21721 aatctcttat ttaaccttta aatctgtaca aatgatcatg gaaataagag atggcatgat
    21781 caaaacatat aagccatttc gttatatcca gtttctgctg ttctttccaa caatctcttc
    21841 tggaccaatc gatcgctata ggagatttga aaaagatcag ctccatccgc ctgttcgtga
    21901 taaatatgtt gatcttttgg gaaaaggcgt ccaaaatatt tttgtcggtt ttttatataa
    21961 attcattatc ggttattatt ttggtcaagt actgcttcct gtagtgggac gcattgcctt
    22021 acagcatggt ggtatttcat gggcattagt aggttatatg tacgtgtaca gtatgtattt
    22081 gttttttgat tttgctggct atagcttatt tgcagtcggt acaagctaca tgatgggata
    22141 tcagacacca atcaatttca ataaaccttt tttatcatgg aatatcaaag aattctggaa
    22201 tcgttggcat atgacgctgt ccttttggtt ccgtgattat gtatatatgc gattgatgtt
    22261 cttcatgatg aagaaaaaat tttttaaaag caagatcgta atgtcaaata tcggttattt
    22321 tgctttgttt cttctaatgg gtatatggca tggattgacg tggtactaca tcgtatatgg
    22381 actgtatcat gcttgtctga tctgtctgac agatgcatgg atccgattta agaagaagca
    22441 taaagagcag ttgccttcta acaaatttac gcatggctta gccgtatttt tgacatttca
    22501 agcagtatgt tttagcttcc tgattttttc aggattttta gataaacttt tttttagcta
    22561 acgaatagtg acatattaat ttatataaca aaggagaaaa ggaaaatgga agaacaaatt
    22621 ttatcaatct tagaagaaat aacaggaaca gatgaagtaa gaaaaaatcg tgatattgat
    22681 ctatttgatg aagggttgct tgattcttta gcatctgttc aattattagt cgagctagac
    22741 ggagagctgg atatccaagt ccctgtatct gaattcgagc gagaggattg gagcacaccg
    22801 aataaaatca ttcaacaagc aactgcattg aagggttgag tatgaaaaag aaactttttg
    22861 ctattttcgg cccggttgtt ttagctgttg gcttactgtt tgtgtttttt acctcctcct
    22921 atcaagtaga tatctctaat ccagaaacga ttagacgtgc ctcttcttcc atgtcagtga
    22981 acgtgttgaa aggagatgcg ataaaaaatt atgcattatc tgaaaaacaa tatattcctt
    23041 tttttggctc aagtgaatta agcagaatca gtccatttca tccgtctgtt ctggcagaaa
    23101 aataccagcg aaactatcgt ccatttttgc tgggagcacc cgggacacaa tcgttaagcc
    23161 aatatatgat gatgcgttct gcaggagatg ctatgaaaaa caagaaagtc gtctttatta
    23221 tttctcctca gtggttcgtt aaaaatggtg taaaaactga ttactttaat acgtattatt
    23281 ctgaacttca aacatacgac tggttgtttt caatgaagaa agtaacgcct gctgatcgct
    23341 atttagctag aagattatta actttctcaa aagtaaaaga gaatgatacg ttgacggcga
    23401 ttctgcaaac gatcaaaaaa gggaagctac ctttacctga atctttgaat cagctgcgca
    23461 gccaatggaa catgctgaag agagaggatg aagtattcag caatattggg ttgaaagatc
    23521 gacagcaaaa aatcgatcat gagtcaaaac gattaccaaa acaataccaa gaaacagaat
    23581 tatccatttt agcaaatcaa attggagaac gagaaacgac gaataatcca ttcgggttga
    23641 aaaacgattt ttatacgcat cgtatccgag cccacgagcc agagctcaaa cagtcacaaa
    23701 aaaattggga ttatcgtttt tcgccagaat tttctgattt tcagctggtc ttggatcaat
    23761 tagcaaaaaa ccataacgaa gtattgttca tcatcccacc ggttaacgag aaatggagcg
    23821 attataccgg actatctcaa gaaatgttac aaggatttgc caaaaagatc aaatttcaat
    23881 taaatagcca aggattcaat cgaatagctg attttgtcaa tcaagcgggt accaactatt
    23941 ttatggaaga cacgatccat ctaggctgga aaggctggtt ggctgcagat caacagatca
    24001 gaccgttttt agaagaaaat catattactg ctagtaagta tcatcttgac gatgcttttt
    24061 ttagcaaatc ttggcaacat caaataccag ataaactaca attaaaataa agaaaacagg
    24121 cgagtgttgc tcgcttgttt tctttatttt tgaatattct gaataaaaga taaaaatacc
    24181 aagtttgcct gaacaaaaat cataagcaat ggtataatca caatatgaat atagaaatgg
    24241 gggaaaacat ttggatacaa aagaagaaca gctacttatt gatttaactt ctgcaaaagg
    24301 agtacctgga aatgaagaag aggtaagaga agtattcaga gaatatgcca aaccattcgc
    24361 tgatgatatt ttttatgacg gtttaggcag tgtgattgcc aaacatggtg ctggcggagg
    24421 ccccaaggtc tttatttctg gacatatgga cgaagttggt tttatggtaa caaaaataac
    24481 cgaaaaagga ttcttggaat tccaaactct tggaggttgg tgggggcaag tcatgcttgc
    24541 tcagcaagtt gaaatcaaaa cacgtgaagg gaaaatcgtc cacggtgtga ttggttccaa
    24601 accaccacat gttttaacac ctcaagtaag aaataaacct tatgaaataa aggatatgtt
    24661 cattgatatt ggcgcatcaa gccaagaaga agccaaagag tggggcatac gtcctggaga
    24721 tatggtcact ccatatattg aatacaaacg aatgaatggc agtaaatatt tactggcaaa
    24781 agcatgggat aatcgtatcg ggacagctgt ttctctgcga gtattagaga atctatctaa
    24841 agaagcacac ccaaatgttt tattcgcagg aagcgatgtg caagaagaag taggcttgcg
    24901 aggtgctcga acaagtacac accttgtaaa tcccgatatt gcttttgctt tagatactgg
    24961 tacagcagga gacactccag gaatgacacc aaaagaagca gattcgattt taggaaaagg
    25021 cccacagatt ttgatttttg atgcatctat gatcccgcat aaaaaattat tgaattttgt
    25081 tattgatgta gcagaggaaa tggatattcc attccaatat acagtgattt ctggcggagg
    25141 aactgatgca ggacaaatgc atttgacaag agatggtgtt ccgtctgtag ccattaccgt
    25201 tcctgttcgt tatctgcatt cccatacatc agtgattcat gaagatgatt atttgaatac
    25261 agtgaaacta gtcacagaat tagtgaaacg gcttgatagt gaaacagttg aaaaaattcg
    25321 gagttatgaa taatgaataa tagaatacct atttctgaat atcggaaaaa agcacgagtt
    25381 tctttggaaa atcaatgggg aatcaatact tggcttgttt tcttatctat aatatttacg
    25441 agcgtcatcc agaacttttt tgacggtttc agtccttttc cggaagaaag catgcagcag
    25501 cacttattga gttttctagt cgataattta cttttattcg cattcaacta tgcattgttt
    25561 tacattgcgc tagtagttgt acggggtggc agaccaaaaa gtaacctttt attttcagtt
    25621 ttccaaagaa agtattttgg ttcgatactt ggcatcaatt tgatcaattc agtcatcaac
    25681 tggctactca acagtttaat ctttctgccc atgtttttaa tcagcggagt gagtacttat
    25741 atgcagctgc ttttcagttc aaatgcggta cctacgggtg tcatgccaga agattttctt
    25801 gatatcagct ttgttttatc gatgataggg atgatttttg tttcagcact catcatgagt
    25861 attgttggcg gtttattcca atttgctgca tggacaaagt tcgactatcc tgatttgtcg
    25921 gttattcaat gtttgaaata tggctggttt ttattgaaag atagaattgg tacgtatatt
    25981 ttgttgcagc tgtcttttat cggctggtat ttgctaggag caatcgcttt gttcatcggt
    26041 cttttgtggg tcattgttta tgtgaatgtg tcagttgcag aattttatga acaagcacgg
    26101 attgaaaaag gaggtccaga cgcctatttt acttagcatg taagcagttt attcatcaaa
    26161 aaaataactt ttgtggtagg ataaatcttt gagggggaat gtacgatgaa attaactgtt
    26221 ttaggatgct taggagcgta tccttataaa aatcaaggga caacaggtta tttgcttcaa
    26281 tctgacgggt tcaatttgtt gatcgatgca ggtagtgcta cgctgatcaa attacaagaa
    26341 caccttgatc cacttgatct agatgctgtg atccttagcc attatcatca tgatcatatt
    26401 gctgaccttg gtgtattaca gtattactgg caacttcatc ctaagagaaa tccggagaca
    26461 ttgctttcaa tttatggaca cacaaaagat tccattcact ttgaagaatt gacgttggaa
    26521 aatgtctcaa aaggacatcc ttattttgaa gctgaagaat taaaaattgg tccttttctg
    26581 attactttta tggaaacaat ccatccagta gtatgttacg ccatgcgtat cgtagaagaa
    26641 acaacgggga aagtattcgt atttacaggt gattcaggtt atttggaaag tttcgctgat
    26701 tttgcgaaag atgctgattt gtttctagca gatacctatc tttttgaagg aaatgaacat
    26761 catcatgccc atttcacttc aaaagaagct ggagaacttg cgaaatcagc taacgtaaag
    26821 aaacttgtac ttacacacct acctcagttt ggtgatttag aacaattgaa aaatgaagcg
    26881 caaaaggcag caggcaaagg gattgatata gaacttgctg cagttgacaa agtgtttaac
    26941 atttaggagg aagaacatga tttttgtacc aaatgaaaac cacgacccaa gaatcaattt
    27001 agcaattgaa caatatttgc tgcaagaaat gcctttagat gaacctattt tgctctttta
    27061 tatcaatgaa ccttcaatca tcatcggcag aaaccaaaat acgcttgaag aaatcaatcg
    27121 agattatgtg gaagaaaatg gcattcatgt tgtccgtcgc ttaagtggag gcggagctgt
    27181 ctaccatgat tttggaaacc tgaactttag ttttatcatg cctgatgatg gggattcatt
    27241 ccgtgacttt gcgaaagtaa cacagccaat catccaagca cttcatgaat tgggtgttgc
    27301 tggggcggaa ttgaaaggcc gaaatgatct agtcattgat ggcatgaaat tttctggcaa
    27361 cgcgatgtat gctaccaacg gtcggatgtt tgctcatgga acaattatgt tcgactctga
    27421 tatcaatgaa gtagtcaatg cattaaaagt aaaaaaagac aaaatcgaat caaaaggaat
    27481 caaatcgatc cgttctcgtg taacgaatat caaaccattt cttccagaag aaaagcaaaa
    27541 aatgacaaca gaagaatttc gtcaagaaat cttgttgaaa attttcggcg tagagtcagt
    27601 agaagaagta aaaacgtacg aattgactga tgaagattgg aaaaaaatca atcgaatctc
    27661 tgaggaatat tatcgaaatt gggattggaa ttacgggaag tctccagatt tcaatttctc
    27721 tcgccaaaaa cgtttttcta tcggttcgat tgaagtccat ttgaatgtct cagaaggaat
    27781 gatcaaagaa gcaaaaatct ttggcgattt cttcggacta ggagatatct ctgacgtgga
    27841 aaaaaaattg gttggacaga aatatgataa agcatctcta tcaaaaatag tcagccaaat
    27901 tgatgtgaag aaatattttg gtgcgataga accagaagaa ttgcttacct tactttattg
    27961 aaaataaaaa atagcggaat ccacatatat ggattccgct attttttata caggattcgg
    28021 gtaatttcga gagagttgaa cagtgatccg atcaatgaaa gtatcttttt cctgcgttag
    28081 tgttcctgtg taacgatccg ctacgtcttt catcatcatt aagtcaaaac gttcctgatc
    28141 atctaattct tctgtgatgc ctcgactaaa taggtttgta tcgtaatgtg cactatgttc
    28201 gcaacaaatg acgaaatgtt cctcttgttc gtgtatcgac aaataaattt ttcgatacag
    28261 tggattttcg atggcatgag tttctctaaa ggaatgctct aaagcgtgga tcaaaagttg
    28321 agccagatcg tcatcgttga taggaagttc ttcgggaaga tctgcttgga aggttatctg
    28381 aatattccgt ttggcagcta acttctggta acgcgctaag ataagatttg tcacctggtg
    28441 gttgcaaaaa gaacacagca tttcgaaatt ttttgcttct tctaatatct tttccacata
    28501 gtttttagct tttgtttggt ccgtatgcat taaatcttgc agattctcca tctcttggac
    28561 aaattccagg cgaagtgtat ttacttcttg gatatgctgt cgaagctgct cataatgttg
    28621 ctccaacaaa tcatttttga tttttaagaa atctacttgt ctccgatctt tgtcggtatt
    28681 taagatgtga tcgattagat tgtagctgat aataacgatt agaatgataa tatataaaat
    28741 cgtagaccaa ttgatcgttg tttgatagat acctaatgcc gtttggatgt aaatcaagca
    28801 atggataatg gctaccaaga cgatccaagg tgtacaagct acataaaaac ggttattctt
    28861 atatgcttcg ccaatgcatg caagtgaagt gactaaagtg cttataacac tagcaatatt
    28921 agcaatcggc attaattcag gaagttctgc aggagtaaaa gttgcataaa gcagaacgcc
    28981 gataaaaatc aaaagttgga acgtacaaaa aattccgtac cattttttat agtaaaacat
    29041 tcggctccaa tagtagcaga tgatgaaagc tgacgttaag ataataaata aatgagataa
    29101 aaaagaatga acgaatggtt caaaaagaat accacttaaa atatcttctg atacagcttc
    29161 aaatcctaat gccaaagcaa agcaacttaa gagaataagt gagtattcaa gacgtttttg
    29221 tttatacatc aagtagatcg tatagaaaaa ggtccctata gcgataaaaa cagcgattat
    29281 catcgtcaat acttgcggca ctgattgtga ataaataaaa ctaatcaatg gtccagttgt
    29341 tcctagataa actttcggtg gcagtccagc atagttctga taaggagatg agactgtaag
    29401 ggtcaatttt tttccgatat aatttgctgg taaatctatc acagccaatg agagtccggg
    29461 attgctttct tcctgataat ctttccgttg gtataaaatc ttttcgccta gatatacagt
    29521 aatccattga tggtttcctt tgattagtaa atttgcttcg tccaacggtt tttcaagtgt
    29581 cgtttccata atgaatgttt cgtctttatc cacggtagga atcgtacgag tgtacttgct
    29641 gtcaaactta aaatcaggat catcttttgt atagaaaacc cacgaatctt ttatttcttt
    29701 catttgattg ctgtccgcag gagaaaaaat aaaataaaag aaataagcaa ttcctgtta
//
LOCUS       DACDAF010000023        29758 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.023, whole genome shotgun sequence.
ACCESSION   DACDAF010000023 DACDAF010000000
VERSION     DACDAF010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.023"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            147..1016
                     /locus_tag="IVZ69_001017"
     CDS             147..1016
                     /locus_tag="IVZ69_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HAP8183122.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            1225..2250
                     /locus_tag="IVZ69_001018"
     CDS             1225..2250
                     /locus_tag="IVZ69_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP8183123.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            2289..3239
                     /gene="manA"
                     /locus_tag="IVZ69_001019"
     CDS             2289..3239
                     /gene="manA"
                     /locus_tag="IVZ69_001019"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HAP8183124.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            3333..5036
                     /locus_tag="IVZ69_001020"
     CDS             3333..5036
                     /locus_tag="IVZ69_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8183125.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            5038..7071
                     /locus_tag="IVZ69_001021"
     CDS             5038..7071
                     /locus_tag="IVZ69_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP8183126.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            7082..7522
                     /locus_tag="IVZ69_001022"
     CDS             7082..7522
                     /locus_tag="IVZ69_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP8183127.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(7722..8849)
                     /locus_tag="IVZ69_001023"
     CDS             complement(7722..8849)
                     /locus_tag="IVZ69_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183128.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(8852..9529)
                     /locus_tag="IVZ69_001024"
     CDS             complement(8852..9529)
                     /locus_tag="IVZ69_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183129.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            9793..11559
                     /locus_tag="IVZ69_001025"
     CDS             9793..11559
                     /locus_tag="IVZ69_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HAP8183130.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            11574..12011
                     /locus_tag="IVZ69_001026"
     CDS             11574..12011
                     /locus_tag="IVZ69_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP8183131.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            12024..13175
                     /locus_tag="IVZ69_001027"
     CDS             12024..13175
                     /locus_tag="IVZ69_001027"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HAP8183132.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(13237..13935)
                     /locus_tag="IVZ69_001028"
     CDS             complement(13237..13935)
                     /locus_tag="IVZ69_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobyric acid synthase"
                     /protein_id="HAP8183133.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(13928..15280)
                     /locus_tag="IVZ69_001029"
     CDS             complement(13928..15280)
                     /locus_tag="IVZ69_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HAP8183134.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(15503..16903)
                     /locus_tag="IVZ69_001030"
     CDS             complement(15503..16903)
                     /locus_tag="IVZ69_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HAP8183135.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            17064..17801
                     /locus_tag="IVZ69_001031"
     CDS             17064..17801
                     /locus_tag="IVZ69_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HAP8183136.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            17926..18405
                     /locus_tag="IVZ69_001032"
     CDS             17926..18405
                     /locus_tag="IVZ69_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HAP8183137.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            18402..19169
                     /locus_tag="IVZ69_001033"
     CDS             18402..19169
                     /locus_tag="IVZ69_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183138.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            19399..19968
                     /gene="lepB"
                     /locus_tag="IVZ69_001034"
     CDS             19399..19968
                     /gene="lepB"
                     /locus_tag="IVZ69_001034"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP8183139.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(20072..20674)
                     /locus_tag="IVZ69_001035"
     CDS             complement(20072..20674)
                     /locus_tag="IVZ69_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP8183140.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            20780..21249
                     /locus_tag="IVZ69_001036"
                     /pseudo
     CDS             20780..21249
                     /locus_tag="IVZ69_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            21355..21939
                     /locus_tag="IVZ69_001037"
     CDS             21355..21939
                     /locus_tag="IVZ69_001037"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HAP8183141.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            21942..23015
                     /gene="prfA"
                     /locus_tag="IVZ69_001038"
     CDS             21942..23015
                     /gene="prfA"
                     /locus_tag="IVZ69_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HAP8183142.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            23008..23847
                     /gene="prmC"
                     /locus_tag="IVZ69_001039"
     CDS             23008..23847
                     /gene="prmC"
                     /locus_tag="IVZ69_001039"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HAP8183143.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            23840..24019
                     /locus_tag="IVZ69_001040"
     CDS             23840..24019
                     /locus_tag="IVZ69_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183144.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            24041..25066
                     /locus_tag="IVZ69_001041"
     CDS             24041..25066
                     /locus_tag="IVZ69_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HAP8183145.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            25241..26485
                     /locus_tag="IVZ69_001042"
     CDS             25241..26485
                     /locus_tag="IVZ69_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HAP8183146.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            26638..27585
                     /locus_tag="IVZ69_001043"
     CDS             26638..27585
                     /locus_tag="IVZ69_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP8183147.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            27719..28348
                     /gene="upp"
                     /locus_tag="IVZ69_001044"
     CDS             27719..28348
                     /gene="upp"
                     /locus_tag="IVZ69_001044"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HAP8183148.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(28487..28729)
                     /locus_tag="IVZ69_001045"
     CDS             complement(28487..28729)
                     /locus_tag="IVZ69_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183149.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            28850..28922
                     /locus_tag="IVZ69_001046"
     tRNA            28850..28922
                     /locus_tag="IVZ69_001046"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:28883..28885,aa:Thr,seq:cgt)
     gene            complement(29041..29679)
                     /locus_tag="IVZ69_001047"
     CDS             complement(29041..29679)
                     /locus_tag="IVZ69_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP8183150.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT        10126 a         5246 c         6059 g         8327 t
ORIGIN      
        1 tttataagag tttttactca ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca
       61 ttttttttaa caaaatcaaa gttattgctt gaaagaagaa gaatccatcg ttaaaataaa
      121 gcttgacgta gaggggagca agaaatatga aagattttca attgggggct gccacctatt
      181 taaaaagtgt agccattcgg gtgaaagacc gagataaaat gattgatttt tacaagaacg
      241 ttgttggctt tgatttgaaa agagaagaaa acgaattagc cattttagga acagaagaag
      301 ctggaagtga aatgttgctg ctggaagaaa gtcctagagc gaatgatcac atgggggtga
      361 tcaaaaagct gaaccgtttt tcattgatta tccctagcac agaagaaatg gcagatatcc
      421 tttgtcgtat ccgtaaaatg aattatccaa tcaaagaagc tttagaagat catggacgta
      481 tggggatttt gctcgtagac ccagaagaga atgaattgga aatttaccat gaagagaata
      541 agaacgacca aagagaaatt ccagaaacaa tggatcaaga agcattatta agaaaatctg
      601 aagaaaaatt cagtaaacta tcaacaggtt cttattttga aaaaatccat ttaaatgtta
      661 ctaacttaac aaaagaacgc caatttctta atcatgtact tggtttgaag gtacataatg
      721 aagaagaggg catccatgta ttgaatgaag gagatttcca tgttggtttg acagaagcta
      781 gcggaggcgc aattgatttg cctacagatg aagtgattgg acttgatttt ctgaaattca
      841 tgatcgatac tgaaagcatg gaaggactga ttgctcactt gcagcaacta tcagttgatt
      901 tcttcttaga caaaaagcac acagtactca caatctatga tgctatagga atcgaatggt
      961 ggttcgtcag tgagccaaaa gaaaagaata aaactgacat tcgatgcgac gcttaacttt
     1021 ttctttctta acgattgtcg catgtctcgt cattttatga acggtcatac tatcgcttat
     1081 tctagagata gaaagagaaa atagtatacc gggggaaact gcgcggtttt tcgcgcagtt
     1141 tttttgtgta aaaaaggttg attcctcata gattaagctt taagcttgga ctgtaagaat
     1201 ctgatagaaa agcaggagaa aaagatgtat ccacacacga aacagcttat tttgaaaaag
     1261 atggaagaag gattttatcc aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa
     1321 acatttacag ccggctttgc ccaagtcgtt cctgaaaagc agctgatgac agaagatctg
     1381 ttgtttgatg cagcctcact gacgaaagtc gttgcaacca cttcattagt tttacgtcta
     1441 ttagaagatg gaaagataga actcgatcaa ccgcttcata aatatcttcc tgaatttgaa
     1501 aatcagacaa tcactttgcg tcatttactg acacatactt ctgatatcaa aacatggata
     1561 ccaaacagag ataagctatc tcaggaagaa ttgatcgccg cttatttgaa gctagaacca
     1621 ggtgagcaac taggaaaaga agtaaaatat acagatgccg gtacgattct tcttgggttg
     1681 atgctagagg aaatttacca agaaactgca gtggaaatct ttcaagaaca agtattggaa
     1741 ccattaggaa tgatgaacag cttatttctt ccttttcctt ccaaaaaaat cgttcccaca
     1801 gaacaactgc cttcgggtga ggttttgcgt ggacaaactc atgatccgaa agcaagagtt
     1861 ttggctgaac atgcaggtaa cgcgggtctc tttattgatt tgaaagacag cattactttt
     1921 gtccaaatgt atttgaacaa gggaaaaatc cgtaatggtc gttttttaga agaagagacg
     1981 attgattctt tactgcaaga tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg
     2041 gacttaaaaa aggatgtaga agacggtcat gcgattcttt ttcatactgg ttatacaggt
     2101 acgtttttct tgattgatat aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta
     2161 catcctgtcg atcatcgtgc ggagtatctc atatgtcgag atgaaattgt tgaaaacttt
     2221 ttgaaagaga aagcggtatt accgaaataa tgctataata gctatgaaaa atgagaggag
     2281 tttgaattat gcaggaacct atgtttttaa aaccagtttt tcaagaaaaa atttggggag
     2341 gaagtcgttt acgttcagtc tttggttttg atatccctaa cgataaaatc ggagaagatt
     2401 gggcgatcag tgcgcatcct catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga
     2461 aaagattaga tgaactatgg tcagaacaca aggaattgtt tggccatcct tcagaaccag
     2521 tgtttccatt attgatcaag atcttagacg cagaagatga tctatctgta caagtacatc
     2581 cagatgatgc ctatgggatg aaacatgaag gtgaattagg aaaaactgaa tgctggtata
     2641 tcatcgatgc tgaacctggt gcagaaatca tctatggtca tcatgcaaag acaagagaag
     2701 aactagctga gatgatcaaa gatgggcgct gggatgacct tttgaagaaa gtaccagtta
     2761 aaaaaggtga tttcttttat gtaccaagcg gaacgatcca tgctattggt aaaggaatca
     2821 tgattttaga aacacagcaa agttctgaca cgacttaccg cgtgtatgac tacgacagaa
     2881 aagatgcgca aggacaaaca agagagctgc atatccaaca atcgatcgat gtaacaactg
     2941 tccctgcgaa aacaccagaa ttacaaatca aagaagtccg aaaagggaat tcatcgatcg
     3001 tcacttattt agaaactgag tttttcaatg tatatgagtg ggatattaaa ggaatcacat
     3061 ctttcaaaaa acaagcccct tatacattga tgacggtaat cgaaggagca ggagaccttg
     3121 tcgttgacgg aaaaacatat ccattagaaa aaggaacaag ctgtattatt ccaaatggcg
     3181 tttctgagtg ggcggtccaa ggtgaactag caatcattgc gtctgaacca ggcaaatagt
     3241 tcccagatag ctgaaagcag cagacggttt ttcgtttgct gctttttcta cataaaatcc
     3301 gtccatcaat aaatagaagt ctggtgaaaa agatggaata caaatggaaa gcaaacaaca
     3361 gcagtcgcgt gtctatgaaa caactgagaa aagctggaca tcacttaaat gaaatgatca
     3421 tgccaaatct aagtctgttt atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt
     3481 ctggcgattt gcacaccaca ttagaagagg tatgccattg gatgatccag ctgcttttac
     3541 ccatcttgat cagttattca ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg
     3601 gtgcaattgc ttctttaggg ttgatcgctc gttccaatgc tccacaaatc gtaggagcga
     3661 tgattatcgg gccgcttgcc ggcatcgtat atgaacaatt tgtttctaga ttccatgtga
     3721 aattcaaggc tggatatgaa atgcttgtca gcaacctact agtaggactg actggtagcg
     3781 ttatttgtat aattggaatc gtttttattg aaccagtttt aaatagtgtt cacttgttgc
     3841 tcgcctccgt tgtgtcttgg ctagtcacaa tgaatctgtt accacttgtc agtctgatct
     3901 tagaacctct aaaagtacta tttttcaata atgcaatcaa tcatggtgta ttgacacctt
     3961 taggaatcga attctcacaa acagtcgggt actcttcctt atttttgatg gaggcaaatc
     4021 ctggacctgg tttagggatc ttactttcta tcctttgttt tgcagaaaaa caggaaaaag
     4081 taaatgcgag tggagcattg atgatccatg cgattggcgg gattcacgaa atctattttc
     4141 catttgtctt gctgcgaccg tatctatttt tagctgtaat ggctggtggg gcaagcggca
     4201 cgttgatatt tcaatggtta gatacgggat tagctgcacc tgtatcgcct gggtcactac
     4261 tcgtgatttt tgccaatgcg ccttatccac aactagctgg ggtaagtata gggatagcaa
     4321 tcagtacatt tgtgaccttc atttgtgcag cgatactatt gaaattacca aataaagaaa
     4381 aagagaacaa aacggtcaaa gaaaggggag aaatcttgga accatctatc attcattccg
     4441 tcatttttgc ttgcgactca ggtatgggat caagtgctat gggagccgcc ctgctgaaaa
     4501 agaaattagc agcagaaaaa atcgatcttt ctgtcggata cagctctatc tatgaattga
     4561 ataaccaagt aaatcagctg gttatcgtgc aacatgaact agcgggtctt gcaagagaaa
     4621 aagtacctca aagtcaaatc tatgtactgg atcacttttt ggaaacagat atcttgctgt
     4681 cacgaataaa agaagcgatc caatttccaa agcgggaaga aaaaaaagag atagcagata
     4741 tcacagaaca aaaaacgtcg cctgctaata ttgtattttt gtataaaaac aacagacgcg
     4801 gctcacaaac tatgggcatg acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt
     4861 ttgttatctc aaaagaatca atagaaaaaa tcaaaatcca agaagaaacg atttatatcg
     4921 cacaaagaga actagctgta actgaacagc tagaagaaaa gatccctcgg ctagttctag
     4981 ttgaacattg ggtagctacg aatgaatacg aaaaactcgt gaagggagaa atataagatg
     5041 tatttatcgc ccagagaaaa acaattatta gcagaatttc tcagtagccc gtcacctgta
     5101 tctatccaaa aaatgatgaa tttattgaag gtcagtaaac ggactattta ccgcgaatta
     5161 gataatcttg aagtctcatt gaaatcggta aatgcttctt tgaaaaaagc agctagaggc
     5221 tcatttgtca ttgaggcatc agaagaagta ttagagcaat taaaagaaaa tacagatggg
     5281 aaaagtaatg acttatccac tgctaaacga caacacgcga ttttagccga gttgttactg
     5341 acgacagagc cgttgagtct tgctcatttc atggaatcat atcgcatcag taataccact
     5401 ttttatgcag atatcaaaca gttggaagaa agtattcgcc aactgccttt ggaaatcatt
     5461 cggaaccagg gatacgagat cgaaggaccg gaaaaatacc gccggcttct gacagcgaat
     5521 gtattagaat tagaaatcaa tgaatatgaa ctttttcata gtatttcttt cgatgcatca
     5581 ctgaattatt tttttcgatt cgttgatccg caacatctat ctcttgcacg caaagtaatc
     5641 ggggaagaat tgatccaaaa aaagaccaat ctaagtgata gaaagcttga acatttggtt
     5701 ttgatgctga cattgacgat ggagcgtgtg acgaaaaatc atttactgac aaatgagaca
     5761 tataatagtc tggcaaacaa agaattacta cagacagcta aacgattgtt ttcacggatc
     5821 gcttctgaga caaaacaact ttatccagta aatgagatcg tcttttttgc aggattatta
     5881 aatgacttca cgaactcatt tgatcagaat ttctttgaag agacgttcga tacacagctt
     5941 gcttatttag taaaacaact gattcaagaa gtaagtgaag agacgaatgt ccatttttat
     6001 gaagatgaaa ctttgtacaa aatgctgttg actcatttat ctggtgtgtt ttcaagagcc
     6061 gttttacaag aagagacact gaccaatccg attttagaaa aaatcatggt tcaatacgag
     6121 gaagttgcga atgcaatccg taaagcagta gagcggattt ttcaagaaaa aaaattatcc
     6181 gaagaagaga tcgcttatat ggtccttcat tttgcgaatt cattggaacg aagtccgaaa
     6241 gaaagcaata tcagtattgc aggattttcg ccaagtggat tagcttctac tagcatgttg
     6301 gaactacgat tgaaaaggta ttttcccttc atccaacaaa ttcatttcta tcggattgct
     6361 gatttaaaaa aaatcgattt acaagaagaa tatgatgttg ttatttctac atctatttta
     6421 ccaggatacg gtggaaaata tattttagtc tccccgctac tgctagaaga tgaagtcaag
     6481 cagctaaaag aagctttttc gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac
     6541 agcaataacg agtggatgat agaagatact tatgaggaaa caatgcattt catggatcaa
     6601 atcaatcaat tactcggtcg tttttttatc caagaactgg ataatcctga gacgatttcc
     6661 gaaacgattc gcagcttatt tccttatttt cctgaaggac tagtaacgga tgaagaggtg
     6721 gttcatcgcc ggctgcttaa gcgatatgaa caagcaccta tcggtattcc tcatacaaat
     6781 atggggttat tccatacatc cagctcattg atttctaaac cgatcttttg tattttcaat
     6841 ttgaaacatc cgttgaccat tgaagggatg gatagacagc cagtcgattt gtcccgtatg
     6901 ttagttatgc tggcgccttc gccaatccaa gaaaaagacg ggattctttt aggaaagatc
     6961 agtggagcaa tcatcatgaa tgacttgaac accgagatct tccgctcagg aaataaagaa
     7021 atcgtttatc agttgttagc gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa
     7081 gatgatacag ctaccagcag aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga
     7141 agcgttgacc gagatcggcc agtggatgac ccaacaaggg ggaatcaaac cggcatatat
     7201 ccaatcaatg atcgaaagac aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt
     7261 gccacatggg actgacaaag atgaagaagt agtagaagaa ggaatctatt tagtccaagt
     7321 gcctgatggt gtggactttg gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt
     7381 agtggcttta aaaaaagaac atcagttagc ggtgctccaa gatttagcct ttttctgttc
     7441 agacatcgac caagtaatgg cgctcagtga tgcggaaacc attgaagaag tccaaatgat
     7501 ttttgaacat ggacatatat aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt
     7561 aataacttca accaagataa aaataagagg agctattttt gttgggaggt tcttattact
     7621 gcggatgcaa gcttttgaaa actatttatt ctagaaaacc gtttatttga aataggggac
     7681 ggtgacaagg tttttgtcac cgcccctatt atttttgtgt tttaatagct cttttttata
     7741 tagatagtgc ccatacctat gaataataaa acgatactcc atataccaag tgtcaagata
     7801 ccattcatga aagtaacctg ttctgaagct agtggcgaga aaatatctcc tcctatgatc
     7861 acattttgaa aatcaacata agaagttggc aagtaatgac tgattgattc tatccatcca
     7921 atcgaagaaa acaagcgata ctctgctaag aaaagacaaa gaagtgtacc taaaagattg
     7981 actagagaat gttcaaataa agcagataga agaaaactga ttgtacttaa aaagagcacc
     8041 cacaacaaca ggaacagaaa gctctggaaa agatactcat acatcggcag gattcgtatc
     8101 tcctgaccaa tgatcgttcc tacaggataa cggaagtctc ccaaaccatt tttgattatt
     8161 actagtatag agacgatcaa aaatggcatc acgagactta gcatagctgc accataataa
     8221 atggtaaaac ggatgctatg tttctttacc atactatccg gtaatagatt gactagagag
     8281 attacctgct ttcttttttc ataagagatg atggaagaaa gaaacaaggc ggttatacat
     8341 aaaatcaaaa aactagaaat cattcctgaa aaaatatttt cgtagtaatt tgctaaagag
     8401 agatgcgctg gcaagtcaaa aatagaatat ctttggatct gatgttcttt catataacgg
     8461 agcaactcga cacgtttttg ttgttcaatg attggaattc cttgtctttg accagaaatc
     8521 agtcgatcca gtatatcttt ttcataatga taagttgctt cgaccatttg ctggacattc
     8581 cctgtgtttt ttgcatgtaa gattgcttcg atcagtttgt tgcttttctc taaactttcc
     8641 acaaattctt tctcattctc atcttctttc aacgtttcaa tcaaacgttg catctcttca
     8701 tagttatgat tcagttcatc gaattctgta taagcaagtt tatgatcaaa aaaaagtggg
     8761 aatgcaaaga gcacgaccaa caatagagga aataaaaagt ttactttgtt ttttagtaag
     8821 agattgcgtt caaatgtaag taaagacata gttacacctc atataattta cgataaatag
     8881 ctaaaatctc ttccatattt gaggattctg tgacgatttc tccatttttt agaaaacatg
     8941 ctttagaaca aatcgattgg atattcgcga tagcgtggga agaaagaaga atcgtcttcc
     9001 cctctttctg ccattgtctg atgaggctat tcaagatatc aatacttcct gggtctaatc
     9061 cgttcaacgg ttcatcgaat aacatgacag atgaatcact gatcaagtaa gcagcaagca
     9121 agacatgttg tttcattcct agagacattt ttccaatcgg caaagtaagg tactcagtca
     9181 tcttcaatcg ttggaaaaca gtttggcatt ctactttgct ctgccaatag tatttgatca
     9241 aagtcaaata atcaacagcc gatagatagt cggataactg attcgttgat tctagaaaaa
     9301 agaaagaccg gcgataatct gtataagcag taggagagat gttgtgaagg gacaattgat
     9361 cataagttgt tggcagcagt tgggcaatgc cattcagcaa agttgttttg ccaaatccgt
     9421 tcggggcaat caaagcagct acttctcctg attctactaa aagattcaat tgtcgaatca
     9481 cacgtttttt accacgtttc atgttcatgt ttttgatcag taatgtcata gataggcctc
     9541 caatataaaa tttaataaca taatagaatg gaaaacatct aaattaaatg ctaacaaaag
     9601 ttattgtttg catattataa aaaaattaaa ataacagttt tatttaaaat tgaagttttc
     9661 tgataccgaa atctttttat tttgctgaca tactcaaacc tttggcacaa agtttcgtgc
     9721 caaagtacga ctatttctct ttttagtaag cggatacaat tagagtatca aaaggagaga
     9781 gggagagaca aaatggaacg gacgattccc aaaaacaaca tttcgctaaa agcgagggta
     9841 caaaaattag gcagtacttt atcaagcatg gtcatgccaa atattggagc actgattgcc
     9901 tggggtgtat taacggctct atttatccca gatggttatt taccaaatga ggctttcgct
     9961 accatggtaa gcccaatgct aacttatctg attcctttat tgatcggtta tactggcgga
    10021 aaagtaattg ctggtgaccg cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt
    10081 gtcggaacag atattccaat gatgctaggc gcgatgatca tgggacctct tggtggatat
    10141 gccatcaaga aatttgatca gctattccaa aaacggatca aatccggttt tgaaatgcta
    10201 gtcaataatt tttcagcagg tcttatcggt tttggattag cgttattagg tttttctgcg
    10261 attggtccag ttgtcgatgc attgactcaa gcaatggcaa aaggtgtaga gatcatttta
    10321 tctgcccatt tgattccatt gacaagtatt tttattgaac cagcaaaaat cttatttttg
    10381 aataatgcaa tcaatcatgg gattttgaca ccattgggaa ctgaacaagt agcagaggct
    10441 ggaaaatcta ttctattctt gcttgaagca aatcctggtc caggacttgg cgtattactt
    10501 gcttttactt tgtttggcaa aggagcagca aaatcttcag caccaggagc catgatcatt
    10561 cactttttag gcgggatcca tgaaatctat tttccttacg ttatgatgaa accgttatta
    10621 ttcttatcag ttataggcgg aggaatgtca ggaagtttca ttttccaatt gatggatgct
    10681 ggactaagag cgccagcttc tccagggtcg atcattgcga ttctagcgat gacaccgttc
    10741 aattcttacc ttcctgttat tttgggcgtg attgttgccg cagctgtttc gtttggtatt
    10801 tctgcagtaa ttttgaaagc ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt
    10861 caagagacaa aggcagctaa gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct
    10921 acattctctg gcgtacaaaa aatcattttt gcttgtgatg caggaatggg atcaagtgcg
    10981 atgggcgctt cgatcttgag aaaaaaagta caggaagcag acttgcctca aacggtgacc
    11041 aatcaagcaa tcagccaact gacagatgac tcgaatacat tgatcgttac tcaggtcgaa
    11101 ctacaagaaa gagcaaaaca aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt
    11161 ttgaattcac ctcgatatga tgaaatcatt caagaattaa gcagcaagca gaaaacatca
    11221 gtttctgaaa ttgagaatga gccagcagaa gagtttcttt cagcaaacat caaacaaatc
    11281 aaagagattc tacttgtcca cgatgatcgt tccggatcag caacaatggg gatgaccgtg
    11341 ctcaaagata tattagacaa gaaccattta actatcccgt taagaaaagt caatatccaa
    11401 gatttaaaag atgaacctga ttcactgatc gtagccaaag aaagtttagc ggaaaaagta
    11461 cagatggctg cacctcaatc cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa
    11521 tacgaatcga ttgcacaata tttgaaacag acagcttaag ggaggaaaac agcatgcaaa
    11581 gtttgccatt cgacatgatc gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc
    11641 gctattgcgg tcagatgctt gtagaagcag ggtgcgttga tgaggaatat atcgatgcca
    11701 tggtagatag agacaaaatg ttatctgttt atatggggaa ttttatcgcg attcctcatg
    11761 gaacagatga agcaaaaaaa tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag
    11821 atggtgtaga ttttggtacc gaagaagaag aaaagattgc gactgttttg ttcggtattg
    11881 caggagtcgg agatgagcat ttgcaacttg tacagcaaat cgcactttat tgcagtgata
    11941 tggacaatgt tgtccagcta gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag
    12001 caattgctta aggagagaga aaaatgagag cagtacattt tggtgcagga aatatcggtc
    12061 gaggatttat tggagaggtt ttggcagcta atggatttga gattactttc gtagatgtga
    12121 atcacacgat cattgatgct ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg
    12181 aatcaaaaga aaaaatcact gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag
    12241 aaaaagtaat ccaagaaatc gctgaagcag atttagttac taccgccatt ggcccgaata
    12301 tcttaccttt tattgctgag ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa
    12361 gcacaacatc tttagatatc attgcctgtg aaaatatgat tggcggttca gcatttctag
    12421 aaaaagaagt gtataaatat cttccggaaa catcatttac tgacaaatat atcggctttc
    12481 caaatgcagc agtcgatcga atcgtcccat tacaacacca tgaagatcct ttattcgtcc
    12541 aagtggaacc tttcaaagaa tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc
    12601 aattaaaagg ggttttatat gtagatgatc tagaaccata tatcgaacgc aaactattta
    12661 gtgtcaatac tggtcatgcg actgtcgctt atacaggtgc cttgttaggt taccagacca
    12721 ttgatgaagc aatgcaagat gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa
    12781 caggaagttt gctgattgcc aaatgggggt ttgatgcaga gcagcatcat gcgtatattg
    12841 aaaaaatcat tcatcgcttc caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc
    12901 ggacaccatt acgtaagtta ggttatcaag aaagatttac acgtccagtg agagaactac
    12961 aagaacataa cttgacttgc ccacatttga cggcaacaat ggggattatt tttaattact
    13021 atgatcctga agatgaacaa agccgtcaat tgcatgaaat gaagatccat gaaaacttgg
    13081 aacaattgat tcaagaagtc acaggaatca atgatccgaa aacaatcggg aatatcaagc
    13141 aaaacgtgaa ccgttatgcc aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt
    13201 gacgaaattt ttgtcacatt cccctttttc gaataactag gctgtttgtc cttcaagata
    13261 gggcagatcc aattctttac cgtaacgttg ttctaaagct aggcggatca aacgagctgc
    13321 caggttctca tttcttgcaa ggataggtcc atggaaataa gaaccgaaga catttcggta
    13381 aatgacacct tcagattggt cttcaccatt atttccttga ccttgtacca ctttccccaa
    13441 aggtcgttca ccttcaccta agaaagtccg accattgtgg ttttcaaatc cataataagt
    13501 ttcattgaat tcttcgttat ggataacgat atcaccgata aaccggttat tttcctgact
    13561 taacgtgtag tgatccagtg cactgattcc ttggatcttt tctccattag ctcccatgta
    13621 gtagtgacct agcaattggt agccaccaca aatggctaac atgacgccat cattttcgat
    13681 atagttgatc aaagaatctt tctttttctg gatgtctttt gaaatgatta attgctcaaa
    13741 gtcttgacca ccgccaaaga aaaccaagtc atatttatca gcatcaaaag gttcatgtat
    13801 actaacgatc tccgtatggc aagaaacccc cattttttct gctatatatt tcaacatcaa
    13861 aaggtttccg ttatcaccat atgtgttcat caaatttcca taaaggtggg cgatattgag
    13921 ttcataatta gccacggttc attcctcctt tgataaatcc ttgagcagct agttctttac
    13981 gaagctgcaa tacagcagtg taagtagcta aaatatagac atgctcagtt ggcaattctt
    14041 tgattttttc gattacttct ggtaattctt ttgtttctgt caatttattt tctggaatcc
    14101 cggcaacttt tagacgtaaa gtcatatctg tatgacggtc tcctccagaa ataacagctg
    14161 ggatatccat atcggcaaag ttttcaaaat taccatccca aatccagctg acatcgattc
    14221 cgtctgcgta attggcattt aataaagcca ctaaagaaaa tggataagga gctagaccaa
    14281 tcatatcgat tacttgattg atacctacag gatttttgac aagtactaat gtacattttt
    14341 tcccattgat attgatgact tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt
    14401 gtttgatttt atcaggatcg acattgaagt actctgccac tgcagtagct gctaaagcat
    14461 tgtagacatt atacataccg ccaacttcga ttccgtattc atgaccatcg atcacgaaat
    14521 ctgctgacac attgtccatc cgtaccatat cagttaatcg ataatccaat tcaggacgtt
    14581 tgaagtcaca atttggacag taatatttcc ctaagtttgc ataagtgatc attttataat
    14641 gcaagatgtg atgacaattt ggacataaga caccgtctgt attgtaatga gccatttgtt
    14701 cacgatcttc ttcatggtca aagccataat attttctagg attgactgtt tcgatagaat
    14761 tgaagattgg tgaatcaccg ttactgataa tcgttgcatt tggtgacttt gcggcaccgt
    14821 ctacaatcat tttataggtc gtatagattt ctccataccg atccatttga tcacggaaaa
    14881 tatttgtaaa taagaacagt tctggtttca tatattctgt gactttgctc aaacttgctt
    14941 catctatttc taggacagca aactttttct gtcctttttt tggttttgcc tgcaagaaag
    15001 tcgatacaat tccctgtacc atattcgcac cagtagggtt ggttagaact tcatcgaatt
    15061 gctggcgcaa aatattgact gttaaagcgg tagtcaatgt tttaccgttt gttccggtga
    15121 caacgacgac ttggtagtct tttgccaaac tatctagtat atgtggatcg actttcagcg
    15181 ctagtttacc tggtaaactt gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg
    15241 tttttccaac tgcaatcgca aaatgactgc gtattcccat tatgtaacct ccaaaaacga
    15301 tttgctgacg aataaattca actaatcata ccatatgttg aaaaaaaggt taaattgctt
    15361 ttcttattct taagaaaagg ttacggctga aagtgcatga aatcggacaa aatcgcatga
    15421 tttaacaaaa aaacagcttg aaacaaaatg attgtttcaa gctgctgtga ttttattatt
    15481 ccctcttacc tatattccca ttttaaccga taataatttt ctcgcttgga tattcatagc
    15541 ctagatctcg tgtttctttt ggcacgaata acatcaatgt atatagcatt ccgatccgcc
    15601 caataaacat cagtgtagca atcgtgattt tgcccacaac agacaagtct ccggtaatcc
    15661 ctaaagataa accagttgtt ccaaacgcag aagttacttc gatgatgatc gagatcagcg
    15721 tttgttcttc tgtagcagat aaaaaaacga tacaaaagaa acacatacca agagaaagca
    15781 taaagacaac gactgatttt cgcacatcat cttgatcgat tctccgtcca aaaatattga
    15841 tgttatcttc acttttgagg aaggaatata gatacaaacc gatgattgct acagtagttg
    15901 ttcgaatccc gccgcctaca gaactaggac tgcatccgat aaacatcagt aaagaaaaaa
    15961 tgatcagtgt tgtgatttga aaatcaccca aatcgtgaat ctgcagacca gcattacgag
    16021 tcgtaatcga ataaaacatc gaattgatcc atttgacact catattggaa tcttggaata
    16081 aatggtcctt ttccaataga taaatcaaga cagttcccga aacaaacaag ataacaaaag
    16141 ctaacacagc taatttggta aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt
    16201 tgtataatag ccattcccgg cactccatca atacaggaaa accaattcct ccgacaaaaa
    16261 tcaaaaacat gatcaggatc aagaaaaaat agtcatgtgc aaagggcttg atggaatccc
    16321 cagtgacgtc aaacccagag ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa
    16381 cggcatcacg ccaacgatca aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc
    16441 caaaaagtaa ttgaaaccag attaaaatag caaaagtgat ccgaatcagt cggacgatac
    16501 cagacaaacg cggttgattc atatccgtca tgatcagctg tcgctgtttc agtgtgatcc
    16561 gtcgtttaga aaaaatgaca aaagcagtag aaatcatcat gatccccaaa ccaccaactt
    16621 gaaataatat ttccagcagt ataataccgt tatcattgaa cacagaattg atatcaaaag
    16681 tcgatagtcc agtcacactc actgtactga ttgccatgaa cagcatgtcc acaaaagaaa
    16741 catggctatc tggttcgcga aaaatcggca tataaaatag aacgagtgat aagaccgtca
    16801 tcaatatata ataaaaaacg atgatttgga tcgatgagaa atgattggca gcaaacttct
    16861 gtcctcgccg ctgcagcctt cgaaagaata aatcaacatg cacagtacta tcctcctgac
    16921 aatagtcgtt tctaccagta tacaagggga attaggaata ctcaaagaaa ttatcaaaca
    16981 gataacaata cagctttcga ttaaaataga aatggcttat aataaggaaa atcctagaaa
    17041 aaagaaggag gaggaataac aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa
    17101 atcaaaaaat aaattatgat acagttctga aaaaaatgat catgcaatgg gagaaagaag
    17161 aagtaaagcc taagatatta atacatacat gctgtgctcc ttgcagtacg cacacattgg
    17221 aattcatgtc tcaatatgca gagatcacgt tatttttttc aaattcgaat attcatccta
    17281 aaagtgagta tttgcgaaga ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga
    17341 aaactgacca tcatgttgcg ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa
    17401 tggttttaac aaaccatctt gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct
    17461 tcaatatgcg attagatctt gttgcgcaaa aagcgcaaga actaggatac gattactttg
    17521 gaagtgccct gaccatctcg ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg
    17581 atatccaaaa gatttacggg acacaatact tgccaagtga tttcaagaaa aacaaaggct
    17641 atgaacgctc tttgcaaatg tgcaaagagt atgatattta tcgccaatgt tattgtggtt
    17701 gcgtgttcgc tgccaagcag caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag
    17761 cttacttaaa aacatcaacc gtagtttttg aggaaaatta aagaaatctt tcggaaaaac
    17821 gtaagaaaaa aataaagaat ttatggtaga aataaggtag actgtataat ttgtccgtag
    17881 taaagtaagg aaacaagaat aaatttcaat gaaggaagag ataagatgcg aaaagtagca
    17941 cctattttga agccaatcgc tgtattaaca atctcgacga ttgtcgcgac tactacaggt
    18001 attgtgaata gttccagcta ccgtgcacca agttcaagtt ctagtactgt agaagaaaca
    18061 acaccaacta cttcagtctc gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc
    18121 actacgacaa gtacatggga cgatacaaca actagttcgt cgtatgatga gacatataca
    18181 actgacagct caagcgaaac aagtaatacg gtaccagatg gcactccatc ggattcaacc
    18241 aatccaagta caagtccgga tacaagtgct agctccgaaa cgataccaag cagtacgact
    18301 gtagatgata acacgcaaaa tgatgatgca gcacgtacag cacagcaaaa ccaagattca
    18361 ggaaataccc aaacgtataa ccagcaagca ggtgattctc aatgacattt ttactagacc
    18421 ttatcaacgg ggtgcataaa ttccttggct atttagacat cagtcctaaa tatcttaacc
    18481 gtggatatac gattttaagt gtgattccca cgctttattt attgagaatt gtttatggac
    18541 tttggcaaaa ccaaaactat cttcaatttt tcttatatgg acttgcattt ctagtgcttg
    18601 tttattttac tgttttaaat gtattttatt actttttaga taaaaacacg aaagccgatg
    18661 tcactcagct ttttgtgaag tatttacctg atgaagcgtt caacatccag acagaagaat
    18721 cgatagataa tggaaattcg atcgataaag tgaatacaca agaggtcatg gtttcttatg
    18781 acgaagatta tcaattgaaa ttagccgaga atatgcggta tttgattgga aatggtgaga
    18841 tcaaaacaaa tgaactcggt cgcatggatg gatttctggt cgatagaaat acattgtatc
    18901 cttattacta tgtcaagaaa acaggagaga aagagtatgt tctaaatatt ggacgaagct
    18961 actcggacat ggaaaaagta gggaccattc gacttgactc aacagaagac acattggaac
    19021 ctgtcggatt gttcatcgtc ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc
    19081 cttatcgtct gaaattgatt gcaaaaaagg cacagtcgca ggaagaacca gtggtttata
    19141 gtcgtagcca aagaagaaga cattcataat gtgatgaaac gccgtgtatc agtggttgcg
    19201 ataaaaacgt ttattcggaa taagggggat gtgacacgtc ttttgtcacg ttcctttttt
    19261 atataacgag aaagataaga cgaacacatc acttattctt tcctttcatt tataaacatt
    19321 gtagaataaa gaaagtacaa cgaagtattg tgaaaaaacg taataaataa cgaggaaaat
    19381 acaagtagga ggtaagctgt gaaagaattt ttgaaaaatt gggggatttt gatccttgta
    19441 ttagcggcta ttttattagc tagagtgtac gtgtttacac cagttactgt aaacgggcat
    19501 tcgatggacc ctacattaag tgatggacaa cgattgattt catctaagat ctcaaactat
    19561 gaacgaatgg atattattac tacaaaggaa ccgggggatg aagaacggat gattgttaaa
    19621 cggatcatcg gtatgcctgg agatacagtc aagatggaaa atgaccagtt gaccattaat
    19681 ggcaaaaagt atgatgaacc ttatctggat gagttcaaaa aagaattttc agaagataag
    19741 ttacaaggag aatatgctta tagctcagga ttccaagcac aagcagaaag ttcatccacc
    19801 tttacgagtg actttgaata tactgtgcca aaaggaaagt atcttgttct aggcgataac
    19861 cgcttgattt caaaagacag ccgaatgttt gggttagtcg acaaagatat gatccaagga
    19921 aaagttgttt tccgttattg gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa
    19981 aagaagctgt gacatgtttt ttgtcacagc ttctttttcc gaaaattcct tcttatttct
    20041 tggagttgct cacttttttt gcaatctcat tttaagcttt ttggctgatg gataagaaaa
    20101 gcgaagcgtt tttgttcata aatagctttt ccccacgatg gaaggtatga ctagtagcag
    20161 agacaaagcc cgttttttcc aatcgattat tcaattcttc ttggctaaag ccattatgga
    20221 ctttcggatg actaatttgt tcattcttgt caaagtctac gatgatcaat tgaccgccag
    20281 gagctaaaat ttcataaagt tttgtaagaa tattctccgt atcaggaatg tgtaaaagta
    20341 caagtgatag aaggatgaga ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt
    20401 ggatcgttcg gacatttttc agatctgctg cttggatctt ttcttctgcc attttcagca
    20461 tagtttctga agcatcggca atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa
    20521 caagcccagt tccgcctccg taatccagca ggactttttg gtggctgtcg cgcggtagat
    20581 aagtagttag ttcttcgcga ataatcttgg ctaatgcttg acggtcaggg gaatcataat
    20641 ggttagcgat ggaatcaaaa atattttttg tcatcaaata gctccttacg taaaactttg
    20701 aaattttaac ttattatagc acgtgaaaag aaagaaagca tgctatactc aattcaaaaa
    20761 gggagaatct agaaagaata tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa
    20821 gtgtgtccga gaaatattac tagacttgcc tgagtggttt gggcttcctg aatcaacgga
    20881 aaaatatatc gaggaatcaa gtaaactacc tttatggtgt gaaaaaagaa aagaagaata
    20941 tttaggcttt atcactcttt cacagacaag tgaagatact gccgaaatct attctattgt
    21001 atgggaataa aaaaagacta tcatcaccaa ggattaggaa caaaactttt taaagaagca
    21061 gaaggttacg cagcaaaaca ttacaaatat ttgcaagtga agactgtaga cgaggggcac
    21121 tactctatat atgatcaaac tatttgtttc tacgaatcat taggattttc aaggttggaa
    21181 gtttttccaa atttatggga tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa
    21241 caaaagtgag caatagattt aatactaatc tgtgcttgat gaaaattctc actgtaaaaa
    21301 atgctgaaaa tcaagtataa taccatagga acaaactgga aggtgaaaaa gagcatggca
    21361 caactatttt ttaagtatgg cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc
    21421 gcacataatt atgaagaaca aaataagcca gttgtcttaa tgacaagcgg tattgataca
    21481 agagatggtt taggcgttgt ttcaagccga atcggactga aacgtaatgc gatgccgata
    21541 tttgaagaaa cagacgtatt tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg
    21601 ctgatcgatg aagcgcaatt cttaaaaaag aaacatgtca ttgcttttac gagaattgtg
    21661 gacgaattgg atattccggt tatggcattt ggtttgaaaa atgattttcg aaacgagtta
    21721 tttgaaggat caaaatattt attgctttat gcagacaaaa tcgaagaaat gaaaacaatc
    21781 tgttggttct gccacaaaaa agcaatcatg aatttacatt atattgatgg aaaccctgtt
    21841 tatgaaggcg atcaagtgca aattggcgga aatgaagctt attaccccgt ttgtcgaaaa
    21901 cattactttc acccatcaat gattacagaa ggagaataag catgtacgat caattacaag
    21961 caattgaaga ccgttatgaa gagcttggag aacttttaag tgacccagaa gtgatttctg
    22021 atacaaagcg ttttatgcag ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag
    22081 tttatcgtcg ttataaagaa gtagtacaag gaatcaccga tacagaagaa ctgcttggtg
    22141 aaaaactgga tgatgaaatg gctgaactag caaaagaaga attatctgaa ttaaaaaaag
    22201 aaaaagaagt cttagaagaa aaaatcaaga tcttgctttt accaaaagat ccaaatgacg
    22261 ataaaaatat catcatggaa atccgtggag cagcaggcgg agacgaagca gcattattcg
    22321 ctggcgatct tttcaatatg taccaaaagt atgctgaagc acaaggctgg aaaacagaag
    22381 tgatggaagc taacgttacc ggaatcggtg gatataaaga agtgatcatg atgatcaccg
    22441 gagacaacgt atattcgaaa ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc
    22501 cttcaactga atcgcaaggg cgtatccata cttccaccgc aacagttgtc gtgatgccag
    22561 aagctgaaga agtagagatc gatattgaag acaaagatat ccgtacagat atctatcatg
    22621 cttcaggtgc tggcggacag cacgtcaata aaacagcatc tgctgtacgt ttgactcact
    22681 taccaacagg gatcgttgtt gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa
    22741 aagcaatgaa aatcttgcgt gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg
    22801 agtatgatgc caatcgaaaa tcagcagtcg gaactgggga tcgttcagaa cggatccgga
    22861 cgtataattt cccgcaaaat cgtgtgactg atcatcgtat cggattaact atccaaaaat
    22921 tagatcagat tttagcaggg aaattagatg agatcgttga tgcattgatc atgtatgatc
    22981 aaacatcaaa actggaagct atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca
    23041 cgggcttctt cttttttaga ggatcatggg aaagaagcat atagtatcca atttttattt
    23101 ttggaacgaa aacaatggaa aaaacttgat tggctccttc atatgaacga agagatttca
    23161 gaagaagaac agcggttgat cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct
    23221 cagtatttgc taggatatgc agatttttat gatcatcggt taaaggtaac tgaagcaaca
    23281 ctgatccctc gaccagaaac agaggagtta gtcgaatggt gtttagacga gacgcctggt
    23341 gtaccgttag aagtgataga tattgggaca gggactggag caattgctat tagtttgaaa
    23401 gcagcaagaa aaaattggca tatatctgct gtggatcttt cagaagaagc attagaagta
    23461 gcgaaagaaa atgctcagaa agaaggaacg aaaatcagtt tttatcatgg agatacatta
    23521 ggaccagtaa tggatcagca atttgatgtg attatttcta atccgccgta catcagtcgg
    23581 aatgaatggg aactgatgga tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt
    23641 gctgagaacg atggattagc tatttatgaa aaaatagcag ttgaagcacc aagcgtacta
    23701 aaatcaaatg gaaagatttt tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa
    23761 atatttcagc aagcatttcc agataaaaaa gtggcgataa aaaaggatct ttttggcaat
    23821 gaacgaatga tccaagttta tggttgaagt tgtggatgaa aaatttttta tttgtttttt
    23881 tattataaaa aaacacttat ttgacaagga tgtaaacgac tttttggttt atcaacaagt
    23941 ttatccacta ttgacaaata gattatccac aaacagtgga aaacttgagg ataaactcag
    24001 acaaaataag aatgtatgaa aaaggggttg tggataaact gtggaaacga aacgatatga
    24061 tgaaacagaa ttgcaagagg cagccgaagc actgaaagaa ggagaacttg ttgcttttcc
    24121 taccgaaaca gtatacggat tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt
    24181 gttttctgta aaagggagac cgcaagataa tccattaatc gtccatgtcg cctcttttga
    24241 acaagtaaaa gagtatgtgg acaactttca tccggcagca gagaagattg tgaagaactt
    24301 ctggcctgga ccattaactt tgatatttaa gatcaaaaaa gacactttgc cctcagttgt
    24361 gacgggagga ttatccacag ctgcatttcg tataccggat aacaaaaaaa cactagaagt
    24421 aatcgaactt tccggtgttc cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag
    24481 tccaacgact gcagatcatg tatatcatga tctacaagga aaaattaccg ggattattga
    24541 tgatggagct acgcgaattg gtgtagaatc cactgttctt gatttaagtg atccaacagc
    24601 catgcctatg attttacgac caggtgcagt aacgaaagaa caaatcgaag cagtcatcga
    24661 atctcctgtt gctattgatc agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg
    24721 gatgaaatac aaacactact cacccgatac acgtgttctg atggtcagag atggcgattg
    24781 gtcaactgca gttcaatggg caaaaaataa gaagatccgt gcaggtgtca tagcaagccc
    24841 cgaaattgcg gatcaagtgc ggacagatac tgcagctgtt tatatgtata acgacaactc
    24901 agtagaagcg gcggctaaag gattgtttgc aggtctaaga ggattagatg aaccaacact
    24961 tggattagat ttgatttttg tacaagtgta tccagaaact ggattgggga atgcttacat
    25021 gaatcgcttg aaaaaagcag caggacaaaa ttattttgaa aaatgatcaa ttggttattg
    25081 tcgcattctt ttagtatgat acaatgctat caagtaaatc ttctatcagt gaacgaaaaa
    25141 ctaagcgtaa ctaatcgtaa tagaagagat acgaatattt ggcaatttgt ttttgatggg
    25201 aaaaataaaa ttgtaggaaa ataaaaagga gctgttgttt gtggtagatt acaaaacgtt
    25261 tgaccctgat ctttgggctg cgatcgccaa agaagaagaa agacaagaac ataatttgga
    25321 gctgattgcc tctgaaaact ttgtctccga agcagtgatg gctgcacaag gaagtatctt
    25381 gacaaataaa tacgcagaag gttatccagg gcatcgctat tatggtgggt gtgaatttgt
    25441 cgatatcgtt gaaaatttag cgattgaccg tgcaaaagaa ttattcggag cgaaatttgc
    25501 gaacgtccag cctcactccg gctctcaagc caacacggct gcttatctcg ctttggtaga
    25561 accaggggac acgatcttag gaatggatct ttccgcaggc ggacatctaa cacatggatc
    25621 accagtcaac ttcagtggca aaacctatca ctttgttgct tacggtgttg atccgacaac
    25681 agaagttatt gattataatg tggtacgtat tttagctaga aaacatcaac caaaattgat
    25741 cgtagcaggt gccagtgctt acggacgaac gatcgacttt gcgaaattca gagaaatcgc
    25801 agatgaagta ggcgcaaaac tgatggtaga tatggcacat atcgcaggat tagtagcagc
    25861 aggacttcat cctaatccag ttccttatgc agatatcaca acgactacca ctcataaaac
    25921 attgcgtggc cctcgaggcg gcatgatttt gacaaacgat gaagcattag caaaaaaaat
    25981 aaatagtgcg gtatttcctg gtattcaagg cggccctcta gagcatgtga ttgcgggtaa
    26041 agcagtagca ttcaaagaag cattagatcc tgcatttaaa gaatatagtg aacaaatcat
    26101 cgccaatgca aaagcaatgg tcaaagtttt caatcaagca attggaacca gagtcatttc
    26161 aggggcgaca gataatcatc tgatgttgat cgatgttcgc gagttaggta taaatggaaa
    26221 agaagcagag agcattttgg acagtgtgaa tatcactgta aataaaaact cgattccttt
    26281 tgaaacacta agtccattca aaacaagcgg tattcgaatc ggcacgccag caatcactac
    26341 tcgcgggttc aaagaagaag atgctgtaaa agtggctgaa ctagttgtca aagcattaca
    26401 agcaaaagat gataacgctc aactagacga agtcaaaaca ggtgtacgcg aattaactga
    26461 aaaatttccg ttgcataaaa aataaaaatt taaattccat tagtaaacag aaaagttcaa
    26521 tgttgggctt ttctgtttat tttttgggaa aacggattct ttgacaatat cggtgatgct
    26581 ctctagtata tgaggtgtaa ttttagtctt cacactaaat ctcagggagg aaaagtcatg
    26641 actgatcgta tctcgttaga aaaggaagca gtagcattca gtgatgcaaa tgcgcctcat
    26701 ccgcgtatct atgaactagc accggaagaa ggaagagttt tactagaaga agtacaagaa
    26761 tcacctgtga acaaatattc cgtcgatatt gaagacttga tggtggatac tggcgaatgg
    26821 ggaaaactca atattcgtct cgtacgacca gaagggaata tggataaatt accagttatt
    26881 ttttatattc atggagcagg ctgggttttt ggcagtgctc aaacccatga taaattgatc
    26941 agagaacttg cggttcgtac gaattccgtc gttgtctttc cagaatatag tcgatcacca
    27001 gaagcaaaat atccaacagc aattgaacaa aattatgctg tgttgcaaca gctgaataaa
    27061 ttagccaagt caaaaaatct ggatctcgag aatctaatcg ttgcaggaga ttcagtaggt
    27121 ggtaacatgg ctacagtcat gacgatctta acaaaagaac gaaagggcct cccaatatcc
    27181 aagcaattgc tgtattatcc agtcacaaac gctgattttg atacagattc ctatcatgaa
    27241 ttcggagaaa actatttttt gacaagagaa ggaatgatgt ggttttggga ccaatatacg
    27301 acgaatgaag aagagcgtgc tgaaatcaca gcttcgcctt tgagagcaaa tataaatgaa
    27361 ctaaatgatc ttccttcagc aatgatttta acgggagaag cggatgtatt aagagatgaa
    27421 ggtgaggctt atgcgcgcaa acttcgtgat gcaggggttc ctgttacaca agtacgcttc
    27481 caaggaatca tccatgattt tgtcatggta aatgctatgg atcagacaaa ggcaacgcgt
    27541 gcagcaatgg cattatctac ttcttggatc aagaaaaaag aataagcttt gcttgtccgc
    27601 aggaaaactt cttttcaaaa acggattttc ttaggaaaaa tggcgagttt gactagtcaa
    27661 tcacttgatt ttgttttaca attaaaaaga aacgacagaa caaaggagag cttaaaaaat
    27721 gggcaaattt caagtgatcg atcatccatt gattcaacac aaactaacta ttattcggga
    27781 caaaaactgc ggaacaaagg tttttcgtga agtagtcgat gaaatcgcta tgttgatggc
    27841 atatgaagta tcacgggata tgccattgga agacatcgtg atcgaaacac cgatcactga
    27901 aacaacacaa aaaacgttgt ctggtaaaaa agtagcgatt attccaatct tgcgcgcagg
    27961 tattggaatg gttgacggta tcttggaatt gattccagct gctaaagtgg gacatatcgg
    28021 tctttatcga gatgaagaaa cattggaacc acatgaatat ttcgtcaaac ttccagaaga
    28081 cattgatgca cgtcagttgt ttgtagtaga tccaatgttg gcaacaggcg gatcagcaat
    28141 catggcaatc gatgcattga aagaacgtgg cgcgtcgaac attaaatttg tttgtttggt
    28201 agcagcacct gagggagtaa aagctttgca agaagcgcat cctgatattg acatctatac
    28261 agcttctcta gatgaaaaat tgaatgaaca tggttatatc gttcctggac taggggatgc
    28321 gggtgaccgt ttgtttggta caaaataagt aaatacgaaa aagggtgtga cacaactttt
    28381 gtcacatcct tttttggtca tttttaacgt ttgatgcaga acagcttttt cacagctttc
    28441 gtttgcatat aaaaaaacca tcccaaaaat gcagagatgg tcaaattcaa atctttttta
    28501 gttctttgta gttaacgatt actacaccct tactttgcgt catcaagttc gcattttctg
    28561 cagtttcatc aatctcaaca acagcggaat ttttcaattg ctttgaaatc gttccagttt
    28621 gcgacttgcc gtgaattgtg aacattacgt gagtattgat cttgaatttt tcaccaattt
    28681 ccgatggtac gatagttgta tcaaattttc caaaagttgc cattttcata aaacctgcct
    28741 ttcacatcaa ttataccacg ttttatgaaa aatatcatga aattaaacta attttccatc
    28801 ggactcttta caatcagcca aatagagtat ataatttctt ttggataagg ccagcttagc
    28861 tcagttggta gagcaacgca ctcgtaacgc gtaggtcgta ggttcgatcc ctatagctgg
    28921 cattaaaaga gaagacagat atatcaagga tttttaatcc attgatacat ctgtcttttt
    28981 gtttaaagga aataaagtat gctttcttag caatagagca tgtattattt ctataaaaat
    29041 ttaggagaat aaaacgacta gcaatatagc tgtgaaatca aatatcacat gaactgccca
    29101 acttgtaatg atcgagttgc ttttaatggc agcttggttg aataacaatc ttgccacccc
    29161 ttgtatcaaa aggatgtgtg ctacagtgtg taaaatattt ccattatcat aagtactgta
    29221 atggataaat ccaaagatga ttgctgacaa gaaactagcg acaggaatgc tgaacttact
    29281 agaaaaaata gcgagaaaat acactgagaa caattcttct ccaagtatca tgataggcaa
    29341 aataataaat aataacgggc tgaaagcctc atttattgga ttgcctgtta aaccccattt
    29401 caaaatttgt tgcaaaaata ccgagactgc ggcactgatt actacattga taaaaaaata
    29461 tttggctata tttttgacag gagcgacagg tttcgagaac atttttttcg tatctttttt
    29521 accaaaaaca agtgtaaatg ctataaatcc agtgatagtt aaagaaaaaa tgctaataat
    29581 ggatggcgca aatagcaacc ctaacaaacc gagtacaacg acaatagtgc ccaatatccc
    29641 ttttttaagt tctatttttt ttcctaaaat gttattcatg ataataactc ctactattca
    29701 gtttttgaag atagagtcag tatacatgaa gagttaaaat aggcaatgtt tttttatg
//
LOCUS       DACDAF010000024        29107 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.024, whole genome shotgun sequence.
ACCESSION   DACDAF010000024 DACDAF010000000
VERSION     DACDAF010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.024"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1030)
                     /locus_tag="IVZ69_001048"
     CDS             complement(<1..1030)
                     /locus_tag="IVZ69_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8183151.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="IVZ69_001049"
     CDS             complement(1112..1801)
                     /locus_tag="IVZ69_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP8183152.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="IVZ69_001050"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="IVZ69_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HAP8183153.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="IVZ69_001051"
     CDS             complement(2328..2831)
                     /locus_tag="IVZ69_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HAP8183154.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="IVZ69_001052"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="IVZ69_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HAP8183155.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="IVZ69_001053"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="IVZ69_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HAP8183156.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="IVZ69_001054"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="IVZ69_001054"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit beta"
                     /protein_id="HAP8183157.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="IVZ69_001055"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="IVZ69_001055"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HAP8183158.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="IVZ69_001056"
     CDS             complement(6443..7462)
                     /locus_tag="IVZ69_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HAP8183159.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8522)
                     /locus_tag="IVZ69_001057"
     CDS             complement(7635..8522)
                     /locus_tag="IVZ69_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP8183160.1"
                     /translation="MTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEVSDKEKT
                     AESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDGQIQATG
                     DLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSMGGVSAL
                     RYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQDYQQMI
                     GNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTGENASHS
                     MLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="IVZ69_001058"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="IVZ69_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HAP8183161.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="IVZ69_001059"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="IVZ69_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HAP8183162.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="IVZ69_001060"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="IVZ69_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP8183163.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="IVZ69_001061"
     CDS             9753..10397
                     /locus_tag="IVZ69_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP8183164.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="IVZ69_001062"
     CDS             complement(10453..10956)
                     /locus_tag="IVZ69_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP8183165.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="IVZ69_001063"
     CDS             11553..12518
                     /locus_tag="IVZ69_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP8183166.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="IVZ69_001064"
     CDS             complement(12617..13789)
                     /locus_tag="IVZ69_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183167.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="IVZ69_001065"
     CDS             complement(13776..14921)
                     /locus_tag="IVZ69_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183168.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="IVZ69_001066"
     CDS             complement(14935..15867)
                     /locus_tag="IVZ69_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183169.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="IVZ69_001067"
     CDS             15984..17063
                     /locus_tag="IVZ69_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP8183170.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17689
                     /locus_tag="IVZ69_001068"
     CDS             17060..17689
                     /locus_tag="IVZ69_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8183171.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(17799..18026)
                     /locus_tag="IVZ69_001069"
     CDS             complement(17799..18026)
                     /locus_tag="IVZ69_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP8183172.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18129..20717)
                     /locus_tag="IVZ69_001070"
     CDS             complement(18129..20717)
                     /locus_tag="IVZ69_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HAP8183173.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20737..21396)
                     /locus_tag="IVZ69_001071"
     CDS             complement(20737..21396)
                     /locus_tag="IVZ69_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP8183174.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="IVZ69_001072"
     CDS             complement(21445..21948)
                     /gene="trmL"
                     /locus_tag="IVZ69_001072"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HAP8183175.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22169..23035)
                     /locus_tag="IVZ69_001073"
     CDS             complement(22169..23035)
                     /locus_tag="IVZ69_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP8183176.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23144..23785
                     /locus_tag="IVZ69_001074"
     CDS             23144..23785
                     /locus_tag="IVZ69_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HAP8183177.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="IVZ69_001075"
     CDS             complement(23847..25208)
                     /gene="mgtE"
                     /locus_tag="IVZ69_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HAP8183178.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25226..26125)
                     /locus_tag="IVZ69_001076"
     CDS             complement(25226..26125)
                     /locus_tag="IVZ69_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HAP8183179.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26127..26924)
                     /locus_tag="IVZ69_001077"
     CDS             complement(26127..26924)
                     /locus_tag="IVZ69_001077"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HAP8183180.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26902..27606)
                     /locus_tag="IVZ69_001078"
     CDS             complement(26902..27606)
                     /locus_tag="IVZ69_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HAP8183181.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27737..28312
                     /locus_tag="IVZ69_001079"
     CDS             27737..28312
                     /locus_tag="IVZ69_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HAP8183182.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28430..29107
                     /locus_tag="IVZ69_001080"
     CDS             28430..29107
                     /locus_tag="IVZ69_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HAP8183183.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8563 a         6169 c         5232 g         9143 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgctag tcttatacga aacccatcgt cccgatgttt tgctgacgga
    17221 catccgcatg cctaaacaaa cgggcatcga tgctgccaaa gaaattttgg ctaaatttcc
    17281 caaagccatc cttttgcttt tgacgacatt caaagatgaa gaatacatcc gcgaagcatt
    17341 ttccatcggt gtcaaagggt atttaatcaa acagaacttg caagcgatta ttccttctgt
    17401 caaatccgct tataatggac aggccgtatt tggtaatgaa atcatcgaga ctttcactca
    17461 aatgatgaag aataaaccga cgattgatag tcatgcttat gcttctttta gtgaacgtga
    17521 gcttgcaatc atcaaagaag tagctgccgg gaaaaacaat aaagaaattg cagatgcctt
    17581 gtacttgagt gacggcactg ttcgcaatta catcagccaa ttactagaaa agctagattt
    17641 acgggatcgc acgcaattgg ctatctattt ttatcagcat ttgcaataag tcttatctaa
    17701 cacaaaaaaa cctgaatgat gctccttcgc atcattcagg tttttttcac atcttctatt
    17761 caattgtccc gcaaaccatt tcctcacgat tgaaagaatc aaggattcgc agggctgcca
    17821 ggattcgttg gattgttcgg cgtgttaggc ggaaaaatag gcgccttgtc taacgttttt
    17881 tctagttttg attcttcacg atcgtctcgt tctacatcag gactttcatt caatttgaat
    17941 tctttttcca tctcatctaa ctttttaaag tcattgccag attcttttgc taatttcgct
    18001 aatttatctt cggtttcttt agccataaag taacgccccc cttttgattt cagcttagca
    18061 tatcacactg aaaaaacaaa agaaaacgct aaccaacgat catttttagc tatttctcat
    18121 ctttaaaatc aagcattttt tgccggtata aaatcgtagg gagaactgtt ttccatacca
    18181 atcatcggat ctactaactg gttatcgatc acttctgctg taagaacgaa atctttagaa
    18241 acagcaggtt ctacctcttc tttcttttct tctccaacaa atgaagaaaa cagatctggt
    18301 tccactgttt ccattacttg gtttttcgtt tcattcgtcc cactgtcatc ttctacaggt
    18361 agcttttctt ttacaacccg tggctctttt gtatagttcc catcttcaaa tggatcattt
    18421 ccgaccaaag aatcttcata agctgctagt ttggtccgga gagtgatatt cattttatca
    18481 ttatccatga tccttgattt caacgtagtc atccggcttg ctgattcatt cgctacacaa
    18541 gtgacatagg cttgctcttc ccctaacaaa atcaacagtt ccttactgcg agtcactgcc
    18601 gtgtagagca aattacgctg aagcatccgc tgatattgat ggaccatggg caaaataacc
    18661 atcttgaatt cactgccttg tgatttatgg attgagcaac aataagaaag agtgatttta
    18721 ttccattcgt ttcttttata agtgacctca tttgcatcaa actggataac taattcatcc
    18781 actttatctt cagaatcttt tgccaagatg atacccgtga tttctcccat atctccattg
    18841 aatacattca attcgggagt attgactaat tggaggactt tgtctcctat ccgataaacg
    18901 gtgtcgttcc aatgtacttc cttttttcca ggtttccctg gattgaatat ctcctgcatc
    18961 attttattta acgcatcgat ccctgcaggt ccccgataca ttggtgctaa tacttggata
    19021 tcttgtgcac ggaatccctt atttttcgct ttttccacaa ttttagagat caagggttca
    19081 atttgataag catcacttcg gaaataggaa cgatcttttt gattctttgt gaaatctttt
    19141 ggcagacgtc cttctttgat ctcatgggca agaggaataa tactagaacc atcaccttgc
    19201 cgataaatct gattgagttc cattttggga atttgttcga tttccaaaag atcatggagt
    19261 acttgaccag gaccgacaga gggaagctga tctttgtctc ctactaagat aacttgcata
    19321 ttcgtcggaa tcgctttgaa taatgtgtta gccagccatg tatcgaccat agacatctca
    19381 tcaacaatca aaagtccgcc ttctaattct ttcgtactga ctgaaggtgt tttttcccgt
    19441 ccattcagcc ccagaagacg atggatcgta ctggcaggca gacctgtcgt ttcgttcatt
    19501 cgtttagctg ctcggccagt tggtgctgca agtagaatag gaaaaatttc ttgggtatat
    19561 tttgaaggat ccaattccag tccgttcaac tctgcaaaaa gattgacgat tccgttgatc
    19621 acagtagttt tccccgtacc tggtcctcct gttaaaataa atagagggga acggattgct
    19681 tcagcgatag cttgttcttg cgaaggtcca tactgtatgc cgaatatttt ttcgatacgc
    19741 cgaatattct tctgcacttc tttttcagga taatggattt cttttttacg actgagaagg
    19801 cgctggatcg aattaccgat cccccattca gaaaagtaca aactgttttc gtaaagatta
    19861 gtctcttctt gttgtatctt tccttcttca acaagttgga taattacagt agcaacctga
    19921 tcaggctgga tttcaattgg gcgacttgtt tctaaaatac ggatcgtttg ctgaagcaat
    19981 gtctccgccg gtacgtatgt atctcctgtt tgaactgcat gctgaaaaat ctgatgcaag
    20041 atagctgctc gaattcttct cggtgaatct gctgcaatac cgatttgttc ggctagatta
    20101 tctgcacgtt tgaacccgat tccttctatg tcttcgacta gctggtacgg attttcttcg
    20161 atgatatcca aagactcgtt cttataggcc tggtagatac tgaaagctaa ctgactaccg
    20221 aacccgtaac gattcagtcc catgatcact tgatccatcc cgtggtttag ccgaatcgtc
    20281 tcagcaagca tttctctttt tggcttcgtc aaaccggaga tttgttttaa taccgaagga
    20341 tcagcaatga ttttttcgat agcatcttct cccagcaatt ctacaatttt ttctgctgtt
    20401 ttcttcccga ttcctgggaa tttttcgctg gaaagatacg ctacgatccc atttgcagtt
    20461 gttggctttt cttgctcata tctttcgagt ttaagctgcc ttccgtattt aggatgatcc
    20521 actaattctc cataaaaacg ataagtctca ttttcttgaa tatcgccgaa acttccggtg
    20581 actacaatct ctttttcacg gtaatcagct gtggtttcac tgatgtgtac caaaagcact
    20641 ttgtaaaaat tactaggatt ttgaaaaaaa atcgcggcaa ctgtaccaac gaaataaggc
    20701 atttcttctg gctgcatcgg aagccgcctc cttcttctat agtaaaggtt ctggtgctgt
    20761 ttcagttcct aaaaaatctg tttggttcca tactttcagt tcatatggca ataatctgca
    20821 aggctcttca gtctctaaaa tcgtcaaact actattgaac aatccaccca tttcacgcaa
    20881 ctcacttagc tcttttcctg tcatccattg aatggctgca gttaaagaag ctccatgtcc
    20941 tacgaataaa agtgggccat ctttatgtcg ggcaaccgca tctgctacaa cagtttcgat
    21001 acgtgtgatt gccgattcaa tcgtttctcc gtgaaaagga gaaggatcat acagatctaa
    21061 atgattacgc aaattcggca gattatccgg atatttctgg tacatttcat cgatcgactg
    21121 accttctaaa gtacccagcc ctagttctct tagcttatct gtataaaaaa tctctaccgg
    21181 acgagcaagc tctttgttga taccttctgc tgtatcacgt gctcgctttg ctgtactgga
    21241 ataaattgct ttaaaaggaa catattttac ctttttccca aatgctttga tttcttcgta
    21301 actttgtggc aaaagcggag aatcgccatt gctcccttga aaacgtcttt cctgattcca
    21361 ttgtgtcttc ccatgtcggg taaaatatag ttccatacgc agcaaactcc tgtctttctt
    21421 ttattttact ctataataaa ctgtctaatc cagcttgtca ttttcatagt gatgcgtcaa
    21481 ttctaaatta gggaatcctt gctggcgaag tgcttcatac actatcattg cagctgtatt
    21541 cgataaattc aatgagcgga catgctcatc attcataggg atgcgtaaac acttttcttc
    21601 gttttcacgc ataaatgttt ctggcaaacc ggttgtttct tttccaaata aaaagaagtg
    21661 ctcttctcca tcagcaaaat tttcgtcact atatacttta tgggcaaatt ttgagatcaa
    21721 atgtagttta cgattaccta aaaatgttaa aaaagcttct aaattactgt ggtaagtaat
    21781 atttacatca ttccaataat ccaaccctgc ccgttttaga tgtttgtcat cagttgaaaa
    21841 acctagtggc tcgattaaat gaagcggagt attcgtggct gcacacgtac gggcaatatt
    21901 tccagtgttt gcagggatta atggttcaaa taaaacgata tgattcatca ggatcattcc
    21961 tctcatattt atgttcgttt ctattttctg acaatttgat ttttgcataa aaaaaaacgt
    22021 atcaactcgg tgtcagtcac tgcgagtcgt tacgttagtg aagctcttct cactaacttt
    22081 tatcagaaca ggaacctgat aaaaaccaat gaaaaaacaa cttgttgcta atataacacc
    22141 ctcaactttt ttttgcaacc tctactcatt aaaaactgct agaaaaacgt tttctcttag
    22201 ttccttttaa taattctatg tcaattgtaa tcttcttcaa aggattctta tataagtctg
    22261 ctttgattcg ctcttctacc tgccattcta aaggtgacat ggccaaaaga tctttttgat
    22321 tttcctctgg tatctcaaat tcataggtta cacgctgacg ttcagttaat ttcattgctt
    22381 cagcaaactt ggctactaca cgttcattgg aataactctg tttttcaggt tgattcggat
    22441 aaaaagcctg acgtagttcc tttaaataat tttcttgtgg caccaccttc aacacttctc
    22501 catcttctga gagtacacgt tggaattctt ggtaatgaga aggcgaaaag atatttaaaa
    22561 ccgcgttgaa tgtttgatca gcaaacggca aattggtcaa atcagctaca caccaaaatg
    22621 cttcggcaga ttgttctgta gctgcgtaga ctccttcttt tgaaatatca aatccaacag
    22681 cattttgaat ctttttcaat tttgaaagtt cattcaagaa gctaccttct ccgcagccaa
    22741 catctaatag cgagacttct tcaggtaaat gctgcgcaat agtctcaata acgggctgat
    22801 acatgccaga ttggatcatt ctacgccttg gaacgaacat tccttgatcg tattctgttt
    22861 taaccgcatg ggataaaaaa taaagtgttc cttttttgga aaggtcaaaa cggtgattat
    22921 ttttgcatat caagccatta tcagactttt ttacttcttc ttggcaaacc ggacagcgga
    22981 acagctgatg attttctgcc aaaaactggc gtcctcggtc aatttttttt aacatagttc
    23041 cccctcattt ctgttttatc ttaccgttag atgctcactt tggcaactgc taaaaatatg
    23101 atacaatgcc tagaagaaag tgaaagataa aggagaagat tagatgatca aagaattttg
    23161 cgctgaaaac tacacatcta ttcctctagc aattgctaga ggagccgatc ggatcgaatt
    23221 gtgtgacaac ttagcggtcg gtggcacaac cccgagtact ggtgtgatcg aagaaacgtt
    23281 aagttatgct ggggaaaaag atatccccgt aatgacgatt attcgtccta gagggggcga
    23341 cttcgtctat aacgatatcg aattgaaaat catgcatact gatttgattg aagcaaagaa
    23401 attagggacg gatggcgtag tatttggttg tcttactcct tcaggctggc tagacgaaga
    23461 ggccttagaa ctattgatcg aaacagcaga agggttgcag atcaccttcc atatggcttt
    23521 tgacagtatt cctgaagatc ggcaattcga agcaatcgat tggctggtag aacatggtgt
    23581 tgaccgtatc ttgactcatg gcggtcctgc tgacaaaact attgtagaaa atttcccacg
    23641 gcttaaagaa ttgattgcct atacagatgg ccgcttaatc attttgcctg gtggtggtgt
    23701 cactgcagag aatgcagcac atgtagctaa agaattgaac gtaagcgaag tacacggaac
    23761 caaaatcgtg gatcttcagt tataatctta taaacaaaaa aacatttgca acaggcataa
    23821 tgcttattgc aaatgttttt gtttttttac ataaaatagc ccataaataa agaagcaata
    23881 ttgaaataaa tcagtacact cgtcaaatcg ctcaaagtcg tgataaaggg accgcttgct
    23941 actgctggat caaatcctag acgatccatt agcatcggga ttaaactacc tgcaagattc
    24001 gccactgtga ttgcaaatag catagccatc cctatgacaa accccaagat aaaattatgt
    24061 ttccaaaaac ctacgattag aaaaatcgtg atccccgtaa cagctcctgt gacaacgccg
    24121 gtcaagactt cagccaaaac aagtcgaaca aatccatgat ctttctcatc agaaatcgca
    24181 agtcgacgaa cagccacagc tagcgactgg gttccagcat taccggcagt tcctgtaatc
    24241 agcgaaatga agactgctaa aatactcgct tcacttacca agtcttcata gtgactgatt
    24301 aaagaagcgg tcgacatacc taaaaacaac agagtgatca gccaaggcaa acgtcgagac
    24361 gctgccttta ctggattttc attaatttct tccacattga ccccggcaag tcctgaataa
    24421 tcgctagcag cttcatcatc aataacgtcg atgatatcat cgactgtgac gattcctaac
    24481 aaatgatcat cataatcggt aacaggaaga gctaagaagt cataatctct aaatgtttgt
    24541 gccacatctt cttggtcgtc gcctacatga actgaaagca ctcgttcgct catcagatca
    24601 gaaatcattg cgtcgtcatc attcacgatt aggtcgcgca gagaaataac ccctactagc
    24661 tgaccttctt gattaacgac atagatgtaa tagattgttt cagctacatc tgcttcgttc
    24721 ttcagcacgt acatcgcaga gcgaacagtt tgattggcta cgatcgaaac aaattcagtt
    24781 gtcatgatcg cgccagccgt ttcatcctcg taatggagaa gttccttgat ttcactggca
    24841 tcgtctgccg acatcaaact taaatattta gcaatttgct ttttatccag cgtattaagc
    24901 aagtcaacag cattatctgt atacatctca gaaagcatat cagctgcata gctaggacgc
    24961 atttcatcta ggtattcttt catatgttcg ttgtcttctt caatcacatc gaacatatcc
    25021 gctaattctt taggcgacag ataggaatag atcagctgcc tgttctcttc tgtaagagat
    25081 tggtagaatt gcccctgctc atagatatgc atctctaaaa aactgtttct gaatgcctga
    25141 atattatttt cccttaaatc ttgagtcaac tgggcaaatc tttcctctaa ttcttgattt
    25201 tcatccaaac caatctcacc tcgccttatt cttcaaaccg tctcacaact gcctccatgt
    25261 ctgcggctaa aggctgcttg aactccagca actcttctgt aaatggatgg taaaaacgca
    25321 gatcataaca atgaagggct tgtcttttta ttcccagatc cattcgcccg ccatacatat
    25381 catcaccgag cagggcacag ccaattgcgg aaaaatgaac tcttatttga tgtgtccttc
    25441 ctgtatgcag ctggatatca actaacgcga tttctgttag tcgcttctct atccagtact
    25501 cagtctgtgc cgaacgtcct tcatcagaga ccattcgctt caatagcgaa gaataatctc
    25561 gggcgatcgg caaatcgata tgtccatgtg ccgataaatc tgaaagcctt ccactgacta
    25621 aggcctgata ttttttcaca aacttctttt cacgaagttg catatctaat tttgcgtgcg
    25681 caaatccatg ctttgcaaaa agcatcaagc cagatgtatc ccgatctagt cgcgtcacca
    25741 catggattac ttggttttcg taaccttgtt ttttataata agcctttaca cgattagcca
    25801 ttgtcccatt tggatggtat tgggcaggaa tagacgaaac gcctgctggt ttatttacta
    25861 ccagaacgtg ttcatcttca tacacgatat cgatcggtgt ttcatccaaa agtacggttt
    25921 catgttctcc ttcagcagga atcacaatgg ttaccttatc atccttagct agagaaaaca
    25981 agacattttc tacttgatca ttaactttga tttgaccgcc ttgaaatttt attttcgcta
    26041 acagaccctt tgagatccct ttttctttta aaaaatattt tacttgctga gaatgatctt
    26101 tctcataatc ccatgtaaac tgcatatcaa tcctcactaa taaaggcatc tttcacacga
    26161 tgccaaaaat gcatatgtcg ataagaagca aaatggatcc gttcttctgc tattcgataa
    26221 taaattgagc ggatatttgc ttttgcgaca ttcaattgat caaccgttac aagataatct
    26281 tctgtatttt ccaattttat ttctagccat tcatcatggg caatcacgat cggagaaccc
    26341 aaagtacgaa acactcgatt attcagtgaa gcaatctctg ccaactgaaa ggcattgata
    26401 ctaggatgga tcacagcacc gccgacactt ttattatatg ctgtcgaacc agtaggcgta
    26461 gaaatcgtca atccatctcc tctaaaactt tcaaacagct cgtttttgat gtatacatcg
    26521 gctaccatcg tacgattggc ccgtttaatc gttgattcat tcagtgctaa aaaatgctgg
    26581 tccggtgttt catccaaata actgatccga acatccagca agggataact aacactttgt
    26641 tcccggttcg ttcgtaagct gtctactagt tcttccagct cgtaatcccg ccaatccgtg
    26701 taaaacccta aatgacctgt atgcacgccc aagaaacgca catcattcag acaatgactg
    26761 tagtgatgga acgccgacaa taatgtgccg tctccgccga ctgagatgac caattctggc
    26821 tcatgatcat ctcgttgaat ccctgcttgt tctaaaagtg cgttcaaacg ttctgtcact
    26881 tctatagtct ttgcttcttt attatgaacg atcgctactt tcatcccctg cctcctctct
    26941 ttcgctttct ttcttcaaaa gcgttcgata gtagacatca tctgattttc ctcttccatg
    27001 ggagaataac cgctgtgctt cttggatttc ttcacggata ctggacatct cttcatccaa
    27061 ctgataggca gcttctgccg cacgctgaag tcgttcactc atttcttctg gaaaaacgcc
    27121 ttgatattta taattcagcg aatgctcaat cgttgcccag aaattcatcg caagagtccg
    27181 aatctggatt tccgccaaaa ttttcttctc accgctgatc agctgtacag gatactcgat
    27241 caccagatga taagaacggt agccacttgc ttttttattt gtgatgtaat ctcgttcttg
    27301 gagaactttc atgtcttttc ttttacggat gatctcaaca acttgatgga tatcttctac
    27361 aaactgacac atgatcctta acccggcaat atcagacatt tcttcttcta aacgtcccat
    27421 tggaatatgc cgtaattgtg attttgttac aatactatcg actggcttga ctctcccagt
    27481 gacaaattca atcgggacat gtcgattttg ttcacggaac tgtttgcgga tcccccgcag
    27541 tttcactttc aattctgata cagtttgttc atatggtgct aaaaatgctt cccaatctcg
    27601 ttccatagct gatacctcta cttcattaac attcattgtt tattctacca tatatgcaaa
    27661 gttttttcgt actcttgatt tatgcattga ccaaaaaaag aaaattaggc aaaatagaca
    27721 aaaaggagtc gatcaaatga cacaaatgct tgaaatcgaa tataaatcta tgctgacaaa
    27781 gcaagagtac gagatattca tcgctcacta tcaattaaca gataaagatt tccgtgtaca
    27841 gactaatatt tatttcgata ccgttgatga acagctgaag aaacaaaatt gtggcctacg
    27901 gatccgtttc gttggtcatc aagctgaata tacattaaaa acacctgctg aaaaagggcg
    27961 tctcgaaaca acggatacct ttataacaga agaagcagaa gcatttatct tcgaaaaacg
    28021 tctgcctcgt tcaggcgcag tttttcaaaa actttctgat ttgaatatcg atcctgcttc
    28081 attaatccaa accggaaagc ttacaacaaa acgagctgaa ttccctattg aagaaggact
    28141 tttagctatt gatgaaagct ggggagacaa tctacacgat tttgaactgg aactagaggt
    28201 aggggatgca tctgtgggaa aaattgcttt tataaatttt ttaaaacgtt tttctttacc
    28261 ttatcgtcct gctaagaaca agatccaacg tatgcttgaa gctaaaaatt agaaaccttt
    28321 cattttcaca aggcacttga gttcattttt ttactttttt ctgttaagtt ataggatgtg
    28381 aaagaatcta gtcactagtt gtatagaatc tattttgggg gagattcata tgatcgaaat
    28441 ctatttattt gttaatcctt taggggaata ctgtttcgaa atggaacaac agttattaca
    28501 atttatcgaa gaagagtacg ggacaccatc aaaagaaaag atgcaatttc gctttcttcc
    28561 tttggtcaat ttgcagacaa ttggggatgt catgcaacaa aaaggaattt ctcagaacaa
    28621 tcttgaggaa cgtaatcact tattctcaat gacttattct gcagcattgg actgcaaagc
    28681 ggcgcagttt caaggaaaga aaaaaggccg ccgttttttg atcaaattgc aagaagcagt
    28741 cggctgtaat gacataccat attctcaaga acttgctgaa tccatatttg aagaaatcgg
    28801 cggcgatttg aatatgttta aagaagatcg tcagtctgac ttcgttaaag aagtattctt
    28861 ttctgatcaa aaaattgctc gggaaatggg catcacaaaa cacccttctg cagtcgttta
    28921 caattatgcc tgcgaccgtg attttggtgt tttagtagaa gtaaaaggta caagtagcct
    28981 ttggagaatc acagagctgt gtaaaacaac agataactca tatcaagttt ttaatggtga
    29041 acatttacat acaaatgatt ctcagttcca ttcaagaact agccatttac acttgctttc
    29101 taattaa
//
LOCUS       DACDAF010000025        28054 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.025, whole genome shotgun sequence.
ACCESSION   DACDAF010000025 DACDAF010000000
VERSION     DACDAF010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28054)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28054)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28054
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.025"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            24..695
                     /locus_tag="IVZ69_001081"
     CDS             24..695
                     /locus_tag="IVZ69_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8183184.1"
                     /translation="MNFLVVLKDTLIERSTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            754..1194
                     /locus_tag="IVZ69_001082"
     CDS             754..1194
                     /locus_tag="IVZ69_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183185.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            1206..1874
                     /locus_tag="IVZ69_001083"
     CDS             1206..1874
                     /locus_tag="IVZ69_001083"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HAP8183186.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            1938..2561
                     /locus_tag="IVZ69_001084"
     CDS             1938..2561
                     /locus_tag="IVZ69_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HAP8183187.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            2617..3003
                     /locus_tag="IVZ69_001085"
     CDS             2617..3003
                     /locus_tag="IVZ69_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HAP8183188.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            3216..4607
                     /locus_tag="IVZ69_001086"
     CDS             3216..4607
                     /locus_tag="IVZ69_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HAP8183189.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            5218..5586
                     /locus_tag="IVZ69_001087"
     CDS             5218..5586
                     /locus_tag="IVZ69_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HAP8183190.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            5766..6707
                     /locus_tag="IVZ69_001088"
     CDS             5766..6707
                     /locus_tag="IVZ69_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HAP8183191.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            6776..7507
                     /locus_tag="IVZ69_001089"
     CDS             6776..7507
                     /locus_tag="IVZ69_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HAP8183192.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            7651..9831
                     /locus_tag="IVZ69_001090"
     CDS             7651..9831
                     /locus_tag="IVZ69_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HAP8183193.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            9851..10333
                     /locus_tag="IVZ69_001091"
     CDS             9851..10333
                     /locus_tag="IVZ69_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HAP8183194.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            10349..11110
                     /locus_tag="IVZ69_001092"
     CDS             10349..11110
                     /locus_tag="IVZ69_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP8183195.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            11241..12575
                     /locus_tag="IVZ69_001093"
     CDS             11241..12575
                     /locus_tag="IVZ69_001093"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HAP8183196.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            12882..13367
                     /locus_tag="IVZ69_001094"
     CDS             12882..13367
                     /locus_tag="IVZ69_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HAP8183197.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            13360..14043
                     /locus_tag="IVZ69_001095"
     CDS             13360..14043
                     /locus_tag="IVZ69_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HAP8183198.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            14169..16814
                     /gene="polA"
                     /locus_tag="IVZ69_001096"
     CDS             14169..16814
                     /gene="polA"
                     /locus_tag="IVZ69_001096"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HAP8183199.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            16859..17695
                     /gene="mutM"
                     /locus_tag="IVZ69_001097"
     CDS             16859..17695
                     /gene="mutM"
                     /locus_tag="IVZ69_001097"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HAP8183200.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            17659..18288
                     /locus_tag="IVZ69_001098"
     CDS             17659..18288
                     /locus_tag="IVZ69_001098"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HAP8183201.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            18340..18672
                     /locus_tag="IVZ69_001099"
     CDS             18340..18672
                     /locus_tag="IVZ69_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP8183202.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            18984..19475
                     /gene="nrdR"
                     /locus_tag="IVZ69_001100"
     CDS             18984..19475
                     /gene="nrdR"
                     /locus_tag="IVZ69_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HAP8183203.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            19498..20871
                     /locus_tag="IVZ69_001101"
     CDS             19498..20871
                     /locus_tag="IVZ69_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication initiation and membrane attachment"
                     /protein_id="HAP8183204.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            20871..21797
                     /gene="dnaI"
                     /locus_tag="IVZ69_001102"
     CDS             20871..21797
                     /gene="dnaI"
                     /locus_tag="IVZ69_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HAP8183205.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            21926..22366
                     /locus_tag="IVZ69_001103"
     CDS             21926..22366
                     /locus_tag="IVZ69_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HAP8183206.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            22510..23211
                     /locus_tag="IVZ69_001104"
     CDS             22510..23211
                     /locus_tag="IVZ69_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HAP8183207.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            23208..24329
                     /locus_tag="IVZ69_001105"
     CDS             23208..24329
                     /locus_tag="IVZ69_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HAP8183208.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            24344..25576
                     /gene="pepT"
                     /locus_tag="IVZ69_001106"
     CDS             24344..25576
                     /gene="pepT"
                     /locus_tag="IVZ69_001106"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HAP8183209.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            25708..26616
                     /locus_tag="IVZ69_001107"
     CDS             25708..26616
                     /locus_tag="IVZ69_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HAP8183210.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            26651..26923
                     /locus_tag="IVZ69_001108"
     CDS             26651..26923
                     /locus_tag="IVZ69_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HAP8183211.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            26934..27980
                     /locus_tag="IVZ69_001109"
     CDS             26934..27980
                     /locus_tag="IVZ69_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HAP8183212.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
BASE COUNT         9432 a         4844 c         6114 g         7664 t
ORIGIN      
        1 atgatgaaaa aagggggaga aaaatgaatt ttttagttgt tttaaaagat actctgattg
       61 agcgatctac atttctatat gttcaattgc aggaaaataa aacattgctg catttttcac
      121 cagagttcca tctagagggg ctaacattag gagaaatcta tcaagcagaa gggctgtcgg
      181 ctgttttgca cttttttaag gtagaattgg aattaccagt aaaagattat atcgagcttt
      241 ctcttgaatc ttgggatcga gcagtggttg aactgtttcc agaaggttta atgatcgata
      301 caaacgatgg gaagatccat ctgactgcag cagaactgca aaaacaaatg cgttatcaaa
      361 tagatgacga aaattctttt tctattttta gacgtcagca aaagattcta aaaagctttt
      421 taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac acagctgttg aaaaaatatc
      481 caggtctgct tcacacgtct attcaatttc ctcaattgat tacgatgatc catcgtttta
      541 tacgtatgca acagctacca tctaagaagc tgtttcttcc attgacggac acatttcgag
      601 tagtcaacag agaagataaa aagaaagtga ttgtgattga ctttaccaga aatcggaatg
      661 tccttcacca agttgcaatg gaaaaggcca attaaggctt tttctttttg gatttttttg
      721 tcataataaa tattagatga tggaggagat aatatgatgc aaacatggtt agaaaggcta
      781 atacgatttc agcagaacta tcacaaactt atgcagggaa gatatgcgaa atttgatcag
      841 ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt tgctaagtcg ttggttgccc
      901 tatagaatcg gacaattgtt gttcatcgtc tttttcggat ggatgatatt tcgtttccta
      961 tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt atttgaaata tcttgataga
     1021 gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag tcaaaatgga tcgaaaaagt
     1081 tatacttttt ttgagtgccc gaattgtcat caaaagcagc gtgcacctaa aggaaaagga
     1141 cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg aaacgaatgt ttaagggaga
     1201 aaagaatgaa attagtatta ttacgtcatg gcgaaagcga agcaaatttt gaaaattact
     1261 ggacaggatg gctagatgtc gccttaacag aaaaaggaaa agaacaagca gcagttgccg
     1321 gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt ttatacctct gttttgaaac
     1381 gtgcgattct taccggacaa gtcgcactag aagaaatggg tcagttatgg cttcctataa
     1441 taaaaacatg gcgtctaaat gaacggcatt atggggatct tgtgggtaaa aacaaagata
     1501 agatgaaaga aatatacgga aaagatcaag taaaaacatg gcgcagagga tatacggaag
     1561 ttccgccgtt aaccgcagaa aatagatttg accgcagata tgatcacttg gatccgcatt
     1621 tgatcccata cggagaaagt ctggaaatga cagtgaatcg gatcattccc ttatggcaag
     1681 atcatctagc accaaaacta aaagatcggc aagatttact agttgtgggt catggtaata
     1741 gcatccgagc actgacaaaa tatttagaag atgttcctga agatcaaatg gatacgatcg
     1801 atatcccaaa tgcacaacca atccagtata cattagcaga tgatttgaca attctggaca
     1861 aaaaaatact ttaaagaaca cctttatcta aaagtgagag atagaaaaaa gaagcaaagg
     1921 aatggaacaa aaggaacatg aaaaattata tatgggactt tgatggtaca ttgtttgata
     1981 cgtatcccgc aatggtagat ggtgcatggc aagcactaaa agattttggt atcagtatgg
     2041 acaaaaaaga aatctacttc aaaatgaaaa agtattctac tagttatttg atcaatgaat
     2101 caaacttgaa tgccagagag tttaatgaat tatttcaccg atatgaaaaa gaaagtacgg
     2161 aagtttcccg tccatttcca gaaacgaaac aagtactgga aatgctaaaa gacaacggcg
     2221 gtcgtcattt catcctgacc caccgtttga cagaatcaac atggggcctg ttaaaagaac
     2281 atcgattggc acatctgatt gaggaagtag tagggatcga tcaggacttt cctcgtaaac
     2341 ctgatccagc atctttaaat tatttgatcg atacttttca tttagaaaga acagacacga
     2401 tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa aaatgcagga gtcgctactt
     2461 gtctttacga catcgatcat tttctgggtg agatcccggc agattatgtg gtaggaaatc
     2521 tgaatgaaat ccttaccttg cagagcatca ttaaaaagta gtatcccctt tcaaaggaga
     2581 tatgttataa ttttcataaa ggagtgataa aattatatgg aaatcagaag acaaaaagaa
     2641 gttgtagaag catttcatta tgatatgaga ttgccgaacc aagaagtaga aacagatttg
     2701 aaagtaggct tctcgccttt aaaagaaacg atcgaaaact atccgaaaga acatagcatc
     2761 gtaggagcac gcttagagtt ccgtttagtg tttgatacat atgttttatc tggaagtgtg
     2821 agtcagatca atcatatcct caatcggaaa attgaaggtc aaaatgatgt cacacaagaa
     2881 gaagtggacg agctagtagc accgttattc gatatcgtac gccgaatgtc ttatgaggtg
     2941 acagagatcg ccttagatca gcctggggta aaattgaatt ttcaatcaga aaaacaagaa
     3001 tagacagtaa aaacatacct gcgatagatt aaagctatca caggtatgtt tttttattac
     3061 taattgtaag caaaaagaat gtcatttcga taaaaatcgt ctaaaatata aaagtcactg
     3121 aaaaaaattt tttcaggagg atggttgaag aatcattctc gggaaccttt acttccttcg
     3181 atggacttgt cattaataat atgaggagga gaaaaatgac aacactcatc acagttttag
     3241 tggttctagt ttttgcggca ttattatatg tgttctatcg tatgcaaaag cgccatacaa
     3301 aattttcaac acgcgtcttt acagcattag gagttggtat cgtctttggc ggtctgcttc
     3361 aattgatctt tggtgtagac gacaaagtcg ttactcaatc aatggaatgg atcgggattg
     3421 taggtcaagg atatgtatca ttcttgcaaa tgctagttat gcctttagtg tttatttcga
     3481 tcattggtgc attcacaaaa atgaaagttt ctgaaaagct agggaaaatt agtgcgactg
     3541 tattgacttc tttacttgga acaacagcta ttgcagcatt gatcggaatt ggttcaacaa
     3601 tgctgttcgg actccaagga gctaaattca cacaaggagc tgcagaaaca gcacgaatct
     3661 ctgaactggc aacacgtcag gaaacagttg aaaacttatc gattccacag cagattttat
     3721 cctttatccc taaaaacgtt tttgctgatt tagcaggtag tcgtgcaaca agtacgattg
     3781 gagtcgttat tttcgcggca tttgtcggaa tcgcttatct aggcgtgaaa agaaaagcgc
     3841 caaaagaagc agcattcttt tcagatttag tcgacagtct gtataaaatc attatgcgga
     3901 tcgtgacgct tgttttgcgt ttgacacctt atggagtatt tgctttgatg acaaacgttt
     3961 tggcaacaag tgattttgca gctatcgtca atttaggtaa atttgtcgtt gcttcttacg
     4021 tagcattgct tgctgttttg attgtccact cactgatttt gattggtgca aaagtcaatc
     4081 caatcaacta tttcaaaaaa gcctttccgg tattgagctt tgcgtttact tcacgttcaa
     4141 gtgctggagc tttgccattg aatatcgaga ctcagacaaa agctttagga gtagatgatg
     4201 caacagctaa tttctcagca agttttggtt tgtctattgg acaaaacggc tgtgctggcg
     4261 tttatccagc tatgttggca acgatcgtcg caccagcagc tggagtgaat gtctttagtt
     4321 tggaatttat tttgatgctt gtggcaattg taacaatcag ttcttttggt gtagctggag
     4381 tcggtggggg cgcaacattt gcttcactga tcgttttagg ggcaatgaac ttgccagtag
     4441 caatcgttgg gttagttatc tctgttgaac cattaatcga tatggcacgt acagcagtaa
     4501 acgtcagcgg tagcatggta gctggtatcg tgacaagtgc acgcatcaaa gatttagatc
     4561 gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa tgcatagtca aaaagaggtt
     4621 gtgatagaag tggtcagctt taagaaataa gaagaagttt cctaaaaata gtttctcaaa
     4681 tttttgtgaa atttcggctt atttccgaga agctacttct gaaacaccgt gaataagagg
     4741 ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc aaacaaaaat agttcctcat
     4801 attttacgtt tggttgagct tattaccgca gatgcaagct tttgaacacc gtttaagaaa
     4861 gaggtcgtga gcctgccgtt tcactctgag tcacaaagag caatttcaaa aaatagcttc
     4921 tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg tcaggagaac accgtttacc
     4981 agaggttgtg acttgttttt agtcacgacc tcttttttta tttattccat ataaatacac
     5041 attatttatt ccgaaaagtg aaagcgcaaa taacaaaaac aaccaactta tttattatta
     5101 aagaaaagcg tatttaagta ggacgattct gttgagagct ttcgtagatt ttcccatttt
     5161 cctatggtaa actgacaaag ttgagaatgt tagaacagat cgtttaggag gaaacagatg
     5221 tttacgaatg aaataaaaat catgctttat gtggacgatg tagaaaaaaa tgcaacgttt
     5281 tggagagcag ttggctttgc ggaaaaagat cgtcaagaaa tggatgggac gcttataatt
     5341 gaagtaggag ttgaggacag tcaaacctca tttctgttat atgatcgagc atttgttgag
     5401 tcccattcac ctggcacagc tactagtgcc ccatctttga tgttttacag taaagatatc
     5461 tttggactat ataaaaaaat gcagacgcaa tcagtcacat taggtgatat ggtacagctt
     5521 ggagaagaat atgtctttaa ctttgctgat cccgatggca actactttgc ggttacaggt
     5581 aaataataga aataaagact ttgtttttct gtgcgaaaca ggaaagcgaa gtctttttaa
     5641 ttcaaataat aatattatgt aaacaaaaaa ctttccatgc gtaattatac acaagcaaat
     5701 aaatcgtcaa atgcgaacgc cttctttata ctgtttagga acgaaaagaa ggaaggaaga
     5761 aatacatgga ttatcaagta ctgctttatt acaattatac aaaaatcgaa gaaccagagg
     5821 aatttgccaa aaatcattta gccttttgca aatctttgga tcttaaaggt cgtattctag
     5881 tagctgaaga aggaataaat ggtactgtgt ctggaaccgt tgaaaacacg actgcctata
     5941 tgaaagcaat gaaagctgat cctcgatttg ctgatacgat gttcaagatc gatccaagcg
     6001 aaggacatgc ctttaagaag atgtttgtaa gataccgtcc agagcttgta agtttaaagc
     6061 tagaagagga cattgatcca aaccaagtga caggtgccta tctttcaccg caagaattta
     6121 aagaagctat tttagatgaa cagacagtgg tgattgatgc acggaatgat tatgaatatg
     6181 acttgggaca ttttcgaggg gctgtacgcc cagatatacg cagttttcga gagcttccag
     6241 actggatccg cgagcacaaa gaagaattta tggaaaaacg ggtagtgacc tactgtactg
     6301 gtggcattcg ttgcgagaag ttttctggtt ggcttgtccg tgaaggattc aaagatgtcg
     6361 gacagctgca tggcggtatt gctacttatg gtaaggatcc tgaagtccaa ggagaattat
     6421 gggacggcaa gatgtatgtg tttgatgaac ggatcgctgt cgatatcaac caagtagata
     6481 aacaaatcgt cggtcgcgac tggtttgacg gaacaccatg tgaacgatat atcaattgta
     6541 gcaatcctga gtgcaatcgt cagattcttg cttccattga aaatgaagaa aaacatttag
     6601 gagcatgtag catagagtgt gcgaaacatc cgcgcaatcg ctatgttcaa gaccatggaa
     6661 tctctccaga agaagcagaa ctgcggttta cagctttaat taaatagaaa acaatagttt
     6721 tgattgtcga ccatttccaa tatgcgctat actagcgttg aggatggtga tccacatgaa
     6781 atcattgatt tatgctattg gggatgtcca tggcaaacat gagctttttg aaaaacttat
     6841 tcactattat gatccaaaga tccatcagct tgttttatta ggggatctca atgatcgagg
     6901 tcctcgtaca aaagaatgtt ttttattagg aaagcaatta gtcgaagaaa caggagccat
     6961 ttacctccgg ggaaaccatg aagaatattt tttgcaattt ctgcaatcac cggaggactg
     7021 gtatgcgcct tatatgagaa atggtggaaa agaaacgttt gaaagcctga ttcacccagg
     7081 ggcatcggag gaatactccc caactgaaat ctcgatgatg atccaatcga gatattcaga
     7141 actgattaaa tttttagtcc agcgcccctt gtattatgaa tgggaaaatt atctttttgt
     7201 ccatgccggt gtggatttga caaagaaaga ctggcgtaag acaagtctaa gagactttat
     7261 ttggataagg gaaccatttc atgaagggaa aaacaataca ggtaagacaa ttgtatttgg
     7321 acatacgatt acaccaatgc tccatggaga tatgcagaca acagacctct ggattcagga
     7381 tcataaaatc ggaatggacg gtggggctgt attcggaggg tcattgcatg gggttgtttt
     7441 tgacaaggaa ggtattcttc aagatattga atatcagaac aacgaaggac cttggcatgg
     7501 aatctgacta atggaaagaa tgaaggagct gtgactttgt tgcggctctt tttattttta
     7561 tagagaatat tgtttctttc agtagtttaa cccaggataa aaagtatgat agaataaaga
     7621 agcaattttt agcagaaaag aggcatttta atgacggaaa atttgaacca gacgatcatt
     7681 cagcttgtac aaaaagaact ttcagactat cgtcctaagc agttgactac tgtacttaat
     7741 ttgttaaatg aaggaaacac tgttcctttt atcgcgcgtt accgaaaaga aatgactgga
     7801 agtcttgatg aagtccagat tcgtgaaatc gaagagcggt atgcctatct tgaaaactta
     7861 gaaaaacgta aaactgaagt gattcggcta atcgatgaac aagggaaact gactcccgag
     7921 ttagaagcag aaatcaccca agccgtgaaa atgcaacaag tggaagattt gtatcgtcca
     7981 tacaaacaaa aacgacggac aaaagcaacg attgctaaag aaaaaggact tgaaccactc
     8041 gcgaagtggc tgatgcagct tacagatgga gaggtgcaat ctgaagcaga aaaatatatt
     8101 gacaaagaaa aagaagtctc ttctgccgaa gaagcgttgc acggtgctca tgagattatt
     8161 gctgaacaag tcagcgataa tgcaaaattt cggacttgga ttcggtctta tacgtataac
     8221 aaaggtatgt atgtcagcaa tgtcaaggat gagcaagcag atgaaaaagg cgtatatgaa
     8281 atgtattatg actttgcaga acccgtccat aaaatggttt ctcatcgaat attagctact
     8341 aatcgtggag aaaaagaaga tattctgaaa gtattctttc aagtagatga agcagcaatt
     8401 ttagcttact tggatcgcca aatagtcaaa aatcctgcct ctccttcttc ttcattcgtc
     8461 agagaagcct atcaggatag ttataaacgc tttattcagc cagcaatcga gcgagaactg
     8521 cgcaatgaat tgactgaaaa ggcagatgag caagcaatcg ctattttcgg cgaaaacctc
     8581 cgtaatcttt tgttgcaacc gccactaaaa ggtaaagttg tcctgggatt tgatccggct
     8641 tatcgtactg gatgtaaact agcagtcgta gatgcgacag ggaaagtttt agcaatcgaa
     8701 gttatttatc ctcataaacc tgcagcgcaa gcaaaaagag aagctgctgg accagctttt
     8761 atccaattaa ttaataaata tcaagtagat atggtagcta tcggaaatgg tacagccagt
     8821 cgggaatctg aactttttgt ggctgagcag ttgaaatccg ccgaccataa aacctattac
     8881 gctatcgtca acgaagcagg cgcttctgtt tactccgcta gcgaaattgc acgaaaagaa
     8941 tttccgcatc tacaagttga agaaagaagt gctgtttcta ttgcccgtcg cctgcaagat
     9001 cctttagctg aattagtcaa aatcgatcct aaagctgtcg gagtaggcca gtaccaacat
     9061 gacgtttctc aaaaacgttt ggctgaacaa ttggattttg ttgtggaaac agcggttaac
     9121 caagtaggtg tggatgtgaa tacagcaagc ccgcagctct tgcagcatat atcaggattg
     9181 aataaaacaa ctgcccaaaa cattgtcatt tatcgtgaag aaaacggaga attcaccgca
     9241 cgaactcaat tgaaaaaagt gccacgctta ggaccaaaag catatgaaca agcaatcgga
     9301 ttcttgcgag tccctggtgg gaaaaacatt ttggacaaca caggtatcca tcccgaaagt
     9361 tattctattg caaaagaaat attaacttca gtccaacttt cagaaaaaga gcttggtaca
     9421 gaagaagcag tagaaaaatt gacacgatta tccgtagaga aactggctga aagcctatca
     9481 gtcggagaag aaacgttagc cgatatttta gctgggctga cacaacctgg acgagatatg
     9541 cgtgatgaga tgccagcgcc cttattacgt acagatgtat tgagtatgga agacttgaaa
     9601 ccagggatgg aattgactgg aacggtccgt aatgtcattg acttcggcgc atttgttgat
     9661 atcggtgtga agcaagacgg acttgtccat atatcgaaac tcagcaaaaa attcgtcaag
     9721 catcctacag atgtcgtgtc agtaggagat atcgtaacag tttggataga acaagtcgat
     9781 acgaaaaaag gtagaatcag tttgacgatg ctttcccctt atgaagagta acaatgagga
     9841 gtaacaaaaa ttgacacaag aagaactgca gcagttagta gaagagatat cattaaaaag
     9901 cttccagctt cctttcaagc accaagcaat gttcaatcca cgcttacgta caactggcgg
     9961 gcgctatcat ttaaacgatc atcatttaga ttttaatgcg aagctatttg aagagtcaga
    10021 cgaagagacg attgcaggaa tcatcaaaca tgaactttgc cattatcatc ttcatctagc
    10081 tggaagaggg tatcagcata aagatatgga tttcaagtat cttttgaaaa aaacaggagg
    10141 gttgcgctat gcaccagcct tgacgaagaa acagataaag atggagtatt atcgatgcca
    10201 agattgttct gccacgatct gccgcaagag aagaatcgat gtacgcaaat atcgttgtgg
    10261 aagatgtcat ggagaaatca aatggattga gacaaaaaga gaagacttta atgaagcaca
    10321 aaaaatcaga tgaaaggata gaaggccttt ggaaaaaagt gagcagagga atctaaaaga
    10381 ctggaatcag ctattaaatt ttttagccgc acctgaagag ggaaattttg aggaactgac
    10441 ggcacctaca cttattttag ctggaaactg tcttcctatc ttagctgata aagcagcaca
    10501 aatgtattta aatggccaag tagatcaatt gtttttggtc ggaggggtgg ggcatgcgac
    10561 tagaatcctt tatgagaatt ttgaaaagca aggatttcat tttgaagatg gcatgagtga
    10621 aagtgaaatc tgtcgtcagt atctaaaaga agtctatgat ttgcccgata aggcttttct
    10681 gatagaatcg aagtctacaa attctggaga gaacgccact ttttcactgg agattcttca
    10741 ttccttagga gctgtaccag aaaaaatctt attgatgaat gatccgacac tgcaacgcag
    10801 gactcgagca acttttgaga aagtatggca aaatgaacaa actattttcg cgaatgctgt
    10861 gccatttgtg ccggaaatcc ttcacttttc tgaagagatc atctttacag caaaagaact
    10921 gaatcatcaa tggcctaagg aatatttcca tgcgctagta ttaggagaaa tggaacgtct
    10981 ccatgacgat gagaacggct atggtccgaa aggaaaagat tttattcctc acattgatat
    11041 atcagaggaa gtttggtctt cttacaccag aattaaagag tcaataaaaa cggatttttc
    11101 tcgtacttga ccattttagc aagcgaatcc tcctttccaa ataaatttgg ttgaaatttt
    11161 caatcgttta taagataatg aggagcgtgt tgaatgtaat agctaaaaga atggacgcta
    11221 gataagagaa gaggattcaa atggaaaatc aaaataaatt gtatcatttt gttggtatca
    11281 aaggttcagg aatgagctcc ttggctcttg ttttacatga acaaggtcta aatgtccaag
    11341 gatcagacat tgaaaaatat ttctttacac aaagagattt agaaaaagca aatatcacga
    11401 ttctgccatt taacgcagat aatgtaaaac cagggatgac gatcattgca ggaaatgcat
    11461 ttcctgattc acatgaagaa atccagcgag caaaagaatt aggtttggaa gtgattcgct
    11521 atcacgactt tattggtcat tttatccaaa attatacgag tatcgctgta acaggctctc
    11581 acggaaaaac aagtacgact ggactgctct ctcatgtatt gagtggtgtc cgtccaacaa
    11641 gttatctaat tggagatgga acaggacatg gtgatccgca agcggaattc ttttcatttg
    11701 aggcctgtga atatcgccgt catttccttg cctattcacc agactatgca atcatgacca
    11761 atatcgattt tgatcatccg gattattata caagtatcga cgatgtattt acagctttcc
    11821 aaacaatggc tggacaagtg aaaaaagcta tttttgcgta tggtgacgat gcttatttac
    11881 gcaaattaaa agcaaatgtg ccgatttatt attatggtgt cacagaaaac gatgatatcc
    11941 aagcacgaaa catcgaacgc acaacttctg gttctgcttt tgatgtctat catggggatg
    12001 aatttgttgg gcacttcact gtaccagcat tcggtaaaca caatatctta aatgctttag
    12061 gtgttattgc agtagcttat ttcgaaaaac tggatctgaa agaagttgca gaagaaatgc
    12121 tgactttccc aggagtaaaa cgtcgattca gtgaaaagat cgtagcagac atgaccgtag
    12181 tcgatgatta tgcgcatcac cctgcagaga tcaaagcaac gattgatggc gcacgccaaa
    12241 aatatccaga taaagaaata attgcagttt tccaacccca tacgtttacg cgtacgattg
    12301 cattgatgga tgaatttgca gaagcacttg atttagctga taaagtttac ttatgcgata
    12361 tttttggttc ggctcgggaa gaacaaggaa acgttaagat tgaagacctt ggagcgaaaa
    12421 tcaaaaaagg tggagaagtc atcaaagaaa ataatgtatc tccattgtta gattatcatg
    12481 atgcagtagt aatcttcatg ggtgctggag atgttcaaaa atttgaacaa gcgtatgaaa
    12541 aacttttaag cagcacgacg aaaaatgtac tgtaatacaa ttactgcagt gtccttataa
    12601 aaatagaaag agggggagtg gcaaaaatct tgccaagccc ccttttttgc aacttatgat
    12661 aaacggtgtt caaaagcttg catctgcggt aataagccca atcaaatcaa aaacatgaga
    12721 agctgttttt tcttggctgt tcttattatt tgatgcagga cagctttttc acgacctctg
    12781 taaactatag gaatctgtta aatcaaggga gcagaacttg ccttttacgc tacttttggt
    12841 acaataatgt atgattaaaa ataaactgga gggtttctat cttgaacata ggtaagccga
    12901 gaaaactagg aaaaacaata aatgaaatcg aggaaggcga ctcgttatcc ttaacagaat
    12961 ctattgaaga taaccagctt ttgctgtatt tgggattgac gaatgatgca aatcctttgt
    13021 atatccaaca tgactttgca caaaaaacag aatatcaaca gccaatcgtt ccatcagtga
    13081 tgctgatggg gatcatcaca agtgcaattt caaagcatct tcctggacca ggatcacatg
    13141 ttgtcaattt ttctgtcaat tttattgaac cggttttcca ttatgaaaca ctgacttttc
    13201 agtttgaggt cataaaagta gataagatga aggatgtggt gacgatttct gtagaagcgg
    13261 agaatacgaa cgaagatcgt gtgttggatg ctgtcgttat ggtccaaccg ccacaagttc
    13321 ctgaattgga aatagcaatc gaaagtgaag gtgaattgaa tgaataatcc aagtacatca
    13381 atgtcaggta tcaatcgttt ttatgcaaaa gtttatggat ttttaggtat gggacttgcc
    13441 cttagtgcag tcacttctta cttggctctt tgggtatttc ctttgcaatt agcaactttt
    13501 atcaataatt ttccactagg ctttgtgggt ctgtggatcg ttgaactgat tttagtaatg
    13561 gttctaggcg taaaagcaca aaagaatccg agcttagcaa tcggtggatt tattgcctac
    13621 tctcttttga atggcataac attagcggtt actcttgcat actacgatat tggaacagta
    13681 acgcaagctt tcttgacagc tactttgatg ttcatgggga tgtctgttgt cggagtaaca
    13741 acaaaaagag atcttagcgg ggttggaaga gcaggacagg cagctttaat cggagtgatc
    13801 attgcactag tcttgaacat cttcattttg agaagtagcg tagttgagct gttcatctcc
    13861 ctactgttag tcgtcatctt tgcagggatt acagcttatg ataaccaaag catccgtaat
    13921 atctatgtcc agacaaacgg aacagcacat agtggaattg ctgtattcat ggcattgaag
    13981 ctgtatttgg actttatcaa cttgttcttg gcgtttctga gaatctttgg acggaacaac
    14041 taaaaaagaa aaaaattcat cagttggggc tataccgaat tatttggtat ggtcccgctt
    14101 tttcttttcg cattccgcag gattctttgt tagaatgaat aagaacttta cagtaaggag
    14161 ttaagaagat gacaaaaaat aaattattac tcgttgatgg gaacagtgtg gcttttcgcg
    14221 cattctttgc gcttcacaat tctcttgaac gtttcaaaaa tagaaacggt cttcatacaa
    14281 atgcaatcta tgcattcaat acgatgtttg aaaatgttat gcaaaaagag caaccgactc
    14341 atgttctggt tgcgttcgat gcaggaaaaa cgacttttcg gacagaaatg tatgcggagt
    14401 acaaaggtgg aagatccaaa acacctggcg aattcaaaga acaaatgcca tatatacgtg
    14461 atttgttgac aggactaggg gtacagtatt acgaattgcc caattatgaa gcagatgata
    14521 ttatcggtac tttggcagaa aaagtagaca aagatcaatt tgatgtcgtc gtgctttcag
    14581 gtgatcggga tttgactcaa ttagctagta aagaagtaaa agtggatatc actgtaaaag
    14641 gtgtcagcga tatcgaaagc tatacaccag aacatgtagc ggaaaaatat gatgggttga
    14701 cgccaaaaca gattattgac atgaagggac tagccggaga tgcctctgac aatatccccg
    14761 gtgtgactaa aatcggtgaa aaaacagcta tcaagctatt gaaacaatat ggctcagtcg
    14821 aaggaattta tgaacatatc gatgaaatga agcaaagcaa aatgaaagaa aatctgataa
    14881 atgacaaaga gcaggctttc ttatcgaaaa aattggcgac catcaatact tcagcgcctg
    14941 tggatgtctc tatcgactca ttgaagtatg aagggaaaaa tctcgataaa ctcgttccgt
    15001 tttataaaga aatggatttc aatcagttcc tttctaaatt gaatatcgta gaagaagaag
    15061 taaaaatgga tgatattttg tttgaagtcg ttcatgaatt caaagaggaa atgtttacta
    15121 cggatatggc gttgtacgtg gaaatgatgg gcgacaatta tcatacagag gaaatcgtcg
    15181 gagtagcgtg ggggacagaa aagaaaattt atgtcacgaa cgatctatct gtattcgaaa
    15241 accgagcgtt ccattcttgg atcactgatc cgactcggct gaaaaaagta tatgatgcga
    15301 aacgaactta tgttgcttta aaccgctata ctggaaaaac gaaaggaatc gattttgatg
    15361 tcttgctagg tgcatacctt ctcgatacga atgaaaaaag cacagatatc gaaggaatag
    15421 ctgctcatta cggatacaac gatatccaat cagatgaagc tgtatacggc aaaggggcga
    15481 aaaaaggttt accagaagaa gaggaactct tttttgctca tttagcgcga aaagtagctg
    15541 caatcaatgc gttgacacca aaattgagcc aagaactggc agaaaaaaac caagaagatc
    15601 ttttccggaa aatggaactg ccattgtcta tcattttggc agagatggaa ataagcggga
    15661 tcaaagtaga tgcgactcgc ttacaagaaa tgaagggcga gttctctgct cgcttaagag
    15721 agatcgaaca aaaaatctac gaagaagccg gcgaagaatt caatttgaat tcaccaaagc
    15781 aattaggagt gatcttattt gaaaaaatgg gattacccgt tatcaaaaaa acaaaaactg
    15841 gatattccac agccgtagat gtactggaac agcttcgtga acaagcacca atcgtagagg
    15901 atatcctcac ctatcgtcaa attgcaaaaa ttcaatctac ctatgtcgag ggactgctga
    15961 aagtgatcca atcagatgga aaagtgcata cccgttatgt ccagacattg acccaaacag
    16021 gacgattaag ctctgttgat cctaatttgc agaacatccc gattcgatta gatgaaggga
    16081 gaaagatacg tcaggcattt gttcctagag aaaaagactg gctgatttat tcttctgact
    16141 attcacaaat cgagttacgc gtacttgcgc atatctcaaa tgatgaacat ttgaaagctg
    16201 ccttcctaga aggtcaagat atccatgcca gcacagcgat gcgtgtattt ggaatcgaaa
    16261 aggcagagga tgtcacacca aatatgcgta ggcaggcaaa agcagtgaat tttggtatcg
    16321 tgtatggcat ctctgattac ggactttcac aaaatctagg aatcagccga aaagcagcac
    16381 agcaatacat cgatacgtac tttgaaaaat acccaggtgt caaagaatat atggaaagaa
    16441 tcgtacgcga agcaaaagac caaggctacg tcgaaacgct gtatcaccgc cgtcgatatc
    16501 tgccagacat caattcaaga aattacaata tccgttcttt tgcggaacga acagctatca
    16561 atacaccaat ccaaggaagt gctgctgata ttttgaaaat cgcgatgatc gaattggata
    16621 aacgattaaa agaaacaggt cttcaagcta cgatgctgtt acaagttcat gatgaacttg
    16681 tcttcgaggt accggaaaaa gaacttgaat cattagataa attggtgaag gaagttatgg
    16741 aacaagctgt ttctcttcat gtaccactga tcactgacag cagttgggga aaaacgtggt
    16801 acgaagcaaa ataaacattg tttaagacag agcaatataa tgaaggtgaa aagaaaaaat
    16861 gccagaatta ccagaagtag aaaccgttcg taaaggattg gaacggttag tagtaggaaa
    16921 aacgattcaa aaagttcagg tcttgtggcc caagatcatc gagcaaccag agacacccat
    16981 ctttgaggct tctcttgttg gcgaaaccat ccaatccatt ggacgtagag ggaagttttt
    17041 aatttttcat ctcgatcatt gtgaactgat ctcacacttg cgaatggaag gaaaatatca
    17101 atttacgaaa gaaaatacac caatcgataa acatacgcat gtacttttct tttttgagga
    17161 tggaagccaa cttcgctaca acgatgtacg aaaatttggt cgtatgacaa tcgtcgaaaa
    17221 aggagcaagt gcaacttacc gaggaatcat gaaattggga cctgagcctt tgccagatag
    17281 cttcttatta gcagatttcg caaatggact gaaaaagtcc cacaaagcaa tcaagccatt
    17341 gctgctagac caacgtctag tgactggtct aggtaatatt tatgtagatg aagcattatg
    17401 ggaagcgaag atccatccag aacaaccggc gaacacactg cgccccaaag aggtagaaca
    17461 attacgtcta tcgatcattg atgttttgga tcgtgcaata gaagccggag gtaccacgat
    17521 tcgcagttat ttgaatgcat taggagaatc aggcggattt caagtagcac tgcatgtcta
    17581 tcagcaaact ggcaaaccat gtatacgttg tggaacgccg atcgtgaaaa caaaagtggc
    17641 acaaaggggg acgcactatt gtccgaattg tcaaaggcta aaaatcgcaa agtaggattt
    17701 gttttaggtt tgacgggtgg aatagctacc ggtaaaagta cggcagccaa agtctttcag
    17761 tctcatggat ttcctttgat cgatggcgat gtgattgcca gagaaactgt tgagcctgga
    17821 acgcttgctc tgaggaaaat tgtatcagtg tttggccaag aggtattgca gcctgatggg
    17881 caactagatc gagggaaact tgggatgatt gtttttccat caaaggaaaa acggcaaaaa
    17941 cttgatcagc tattagatcc gtttatccga aaagcgataa aagatcaaat cgcctctcta
    18001 agttccaatc atcctttagt aattgtagat atcccattgc tctacgaagg tcattatgac
    18061 cactatatgg atgcagtagc tgtcgtttat actacgccag aaactcagct tcagcgtttg
    18121 atgaaacgta atcaactgac gctagaacaa gcgcagcaga gaattagtag tcaacttcca
    18181 atcgaagaaa aaaagcagcg tgcggatatt ttgttcgaca acaatggaac aaaagaaaaa
    18241 cttgtgggac aaatcgaaaa ttggcttttt gctaatcgct ttctttgagt atctgtgtca
    18301 attttgctat cctgagtata tagaaagtga gggatagcga tgggatcatt aaaaaatcaa
    18361 aaggataaag tcgtaggtaa cgcaaaagaa aaaatcggcg agatgctcaa taaagaaaat
    18421 ctaatcgatg aaggtcgtac gcaatcagaa acagcagaag aaaaagaaaa gcagtaccaa
    18481 gcaagaatcg atgaaataga agaccagcag gcagaagaag aagcgaagcg gcaagatttg
    18541 actcaagaac gaaaaaatcc gacacctgat cgtagtaaaa caccgctccc agaaagtgac
    18601 cacattcccg atgagcaaaa aatcgaggaa cagcgaatga aacactatac aggaatcgaa
    18661 gagaagttat aaaatagtaa aaaatcgaga tgtgacttga agcagatgag aaggtgttca
    18721 tctgcttcaa gttttttgtg ctagatgact aaatcagctt ttgtgtaagt tatttctcag
    18781 taatcaaggt gatcagtatt ggaaaattga aatttagtaa ggacagggga cacaattacg
    18841 catgaaagta gaaaaaattg ttcttatatc cgtgtttttt gggtaggaca gtcgcgtttg
    18901 tgatttgttt cgtgttataa tacaactagt tgtaaagaaa gacacatcct ttatataaaa
    18961 tgcgatgcaa gaggtgagac aaaatgagat gtcccagatg tcaacataat aattcacgag
    19021 taatcgacag ccgtcaagca gatgatggac gtgcgatccg tcgccgtcgc gaatgtgaga
    19081 attgttcgtt ccgattcact acatttgaac gaattgaagc tgctccgtta ttagtaatca
    19141 agaaaaacgg ggaacgcgaa gagttcaatc gcgataaaat tttaagagga ctcatccgtt
    19201 cagcagaaaa aagacctgta gctatggaac aaatggaaca aatcgtcaac catgtcgaaa
    19261 accgcgtacg cagtctcgga gaaaacgaag tatcgacgaa tctaattggt gaatatgtga
    19321 tggaagattt agttgattta gacgaaatcg cttatattcg ttttgcaagt gtttatcgcc
    19381 agttcaaaga tatgtctgtt ttcttaaaag agttgcaaga tatcgtggat aaagcaaaag
    19441 aaaataataa agagaataat aaagaaaaca attaagaaac aaaaaggagg catttccttg
    19501 gaaaatgctt ggaaagagct tcaaccaaaa aatatttacc aaggaagaaa agcggctccg
    19561 ctgagagaag acagcaagaa cgccttgctg tatctttatc agccactaat cggcggagaa
    19621 gccttgagta tctatttcac cctgttatca gaaatctctc aagaatctgg caaaggtcct
    19681 gaagggatgc atgcagatct gcttagtagt ctaggctgcg gtatcccgca attttatgat
    19741 gcaagaaaaa agctagaagg aatcggctta ctggatgttt attttaaaga agatagtgat
    19801 ctgggacctc gttttattta tgagctgtta gaaccactca ttcctaaagc atttttcaaa
    19861 gactctgttc tggcttttct tcttctggaa aaagttggtg aacgacgatt ccagaagctt
    19921 acccaattct ttgaacctaa aaggcataca gcagagggat atcaaaaaat cacaaaaaaa
    19981 tttttagatg tttatcgctt caatgaagca gtgtacgctg ctaatcaaga aaacatcgaa
    20041 tcgctgaata aatcttttga agaatctgaa tcagtagcat tacttgaagc agattcgaca
    20101 ttcgattggc agtttttgaa tgattggctg gcaaaaaaac atattgcaag tcttgatgat
    20161 ccaatcatca aacaagtcga catgtatcat cagctttacg gtttcgatga attgacactt
    20221 ggcgaactga tcagtcaatc ttatgacttt agtgaacaaa aagtatctga aaaagaactg
    20281 caaaaagcca ttttggcaat gcagagacgt ccggtgaagc aaacaaaaga aacagttgcg
    20341 gtttctgaaa acagtaatga accctcgtca aacgaacatt tgacaaacgc agcgcttcag
    20401 ctgataaaag aagcacagag cattccaccg atgaaatatc tggaagcaat caagtcagaa
    20461 aaaggcggat atgtttctaa acaagaaaac tggttactgc aagatcttgt ttctcaatca
    20521 ggtctttcca gtagcgtgat caatgttttg ctgaattatg tactagtgat caagaataat
    20581 gctagcttaa atgccagtta tgtaaataca gtggcaaatg aatgggcaca aaagaaaatc
    20641 gccacagcag aagaagcgat ccagcacatt cggcaaataa gtaatcaagc aaaacaatca
    20701 aaacaaaaga agcaaacaaa ttatcaaact ggcaagcgaa atgttcgacg ggaaaagctt
    20761 cctgattggg tcaaccagcc aaaagatgaa aaacagatca gcagcgagaa aaaagcagag
    20821 attgaccgcc gttttaaaga atacctggca aaaaaggagg gtgatatcta gtggaagacg
    20881 taggcaaaga attgaagagg atcatcagca aacgcaatta tcaagaaaag tatgctgaaa
    20941 tgatcgctga agtcttaaat gatgcggatg ttcaagcttt tctaagcgca caccaagaag
    21001 aattgacaca agcggatatt gaaaaaagtt acgctaaatt gtatgaattc gtgcaagaaa
    21061 agcgtaaata tcaaaaaaac gatccaacga tgatcgctcc cggctatgag ccgaagctga
    21121 cgttgaattt tcattatgtg gatgtcactt atgtaccaac ggaagcattg ttagcacggc
    21181 aaagacaaga agaaatcaga agccgagtaa aagcaatgga tatgccaaaa gatattcaat
    21241 cggcttcttt tgaaaacttt gaacgtacag atggacgagg atatgcgagc ttagaagccc
    21301 tagattttgt agagaaatat actgctgatc caaaagggta tcataaagga ctgtatctag
    21361 taggaagttt tggtattgga aaaacatatt tattaggagc aacagcgaga gaattagcga
    21421 ttgctggatt caccacgacg ctagtccatt ttccgacatt tgccgttgag atgaaacagg
    21481 caatcggaaa agatcaagtg gcagaaaagt tagatgcagt gaaacgttca cctattttga
    21541 tgatcgatga cattggtgca gatgcgatga gtagttggat acgagacgaa gtattcggtg
    21601 ttatccttca atatcggatg caggaacagt taccaacctt cttctcatcg aattttacaa
    21661 tggatgaatt ggaacagcat ttgtccgtca ctcaacgtgg agatgaagag ccgctaaaag
    21721 cgaaacggat aatggaacgc atacgttatt tgacaaaaga aatcgaaatg actggtcgca
    21781 accgacgcaa tggttgaaca gttgacaagt ccaactgaca tttgacctag tagtaaaagc
    21841 aggtcagcga atcattatat ggacagaaat gaccggagac aatcaccgca acaagtaatg
    21901 cagaaactta aacggaggat tttttatgag ggctattttt tctagtatat ctgtagttgg
    21961 tctatttttt cttttagcag gctgcggtag cgcagatagc aacacaggtt ctgttgattc
    22021 gattgatgcg ggtcaaacag taaaaacaag cagtacgaaa acggagagac aaagcatatt
    22081 tgtcggaacg attgaaagta tcactcaagt agaagcagaa gaagaaacgc ttcagttgaa
    22141 actcgtcgat gtcatggcca aagaagatcc agcgaatatg ggaacgtcat tcagcaatga
    22201 cggagtgatc ttaaatgcta ctgctgaaaa aataagcgtg gacataaatg aattgaaaat
    22261 cggtgacaaa gtccaattta cattagttga gatgccgatc atgacgatgt ctatcccacc
    22321 gcaagttcct ggagattcga ttattgatgt ttcattgaac aaataaccaa taacattttt
    22381 tcaaaaataa gaaaatgttg ttttatagaa cgaaaaggta tattttttaa ggagatatgg
    22441 gaattttttt attcctagtc tccttatttt atttggaaaa tgctataatt atctagaagg
    22501 agtgaagcta tgaaccattt agatttatct cagcgcttag ccgcagtggg tgactttgtc
    22561 cctgaatccg ctcgtttagc agacattgga tcagatcacg cttacttacc cgttgcattg
    22621 atattaagag gaaaaatcga atatgcagtt gctggtgaag tcgttcaagg tccttatgaa
    22681 tcagcacgta agcaagtcaa aaaagatgga ttagaagacc gtatcaccgt acgccttgca
    22741 aatggtctag atgctatcca gccacaagat ggtattacag ctgtcacgat tgcgggtatg
    22801 ggaggttcac tgatccgaga tatcctagaa gctggcaagt tgaatcaacg cttaagcgga
    22861 caagaacgtt tgatccttca gccaaacatc ggagagcgta cattacgatc ttggctgcaa
    22921 gaaaatcagt ataaaatcca atcagaaaaa atacttgaag aaaataaaaa aatatatgaa
    22981 atcattgtag ccgaaaaaga acaaaaacca gttacttaca atgaaatgga gctgatgttc
    23041 gggccatttc tgcttgaaga gaaaagtgag atcttcaaat caaaatggac aagagagctt
    23101 caacaaagaa aagctatccg tgaacagctc aaacaagcag ctaatcaaga ggcacgtcaa
    23161 aaacaaatcg agcaggaaat ccaaatgatt gaggaggttt taaagccatg acaatcagcg
    23221 gacgcacttt catccaaaag tttgaaagct attgtcctca gtggctagct gaagaaggag
    23281 acccagtcgg actgcatatc ggaacattgg ataagccaat ccaacgagta atgatgacat
    23341 tagacgttcg tccagaagtg gtcgaagaag caatcaagaa aaaaatcgat ttgctgattg
    23401 ctaaacatcc tccaatcttt cgtcctgtaa aacggctggt tactgatcag ccacaagaaa
    23461 aaatgtatgc agatttgttg aaacatgata ttgccgtcta tgcagcacac acgaacatgg
    23521 atattatttg ggatggactg aatgactggt tttgtgaact tctcggtatt gaagtggaga
    23581 gttatttagt aaagactcat gagattcatt ataaaaaact ggccgtttat gtacctgtgg
    23641 atcatgcaca gaaaatgcgt gaagtattag ctgcagctgg tgctggtaca caaggtgatt
    23701 ataccggtac aagttttacc tcgattggac acggtcgatt tactccggaa gctggtgcac
    23761 aaccagcgat tgggaaagta gggaagacag aacaagttca agaggcaaaa gttgaggtta
    23821 ttttgccgga aactatcgaa aaacaagtga ttcaagccat gcggtcagct catccttatg
    23881 aggaacctgc ttatgatctt ttcgctatag atgaaccagt cgaaatgttt gggttaggac
    23941 gagtaggtga attgccgcaa gaaatttcta tagaggcatt tgtagaacaa gtaaaagaag
    24001 cgttccaact agatggactg agaatagtcc agccaaaaaa tgcaaaatcc tctgtgaagc
    24061 gcattgcgat ttgcggtgga agcggtgaaa aattttatcc gcaagcaatc gcccaaagag
    24121 cagatgtcta tatcacggga gatatctatt atcatacggc tcatgatatg caaagcgctg
    24181 ggttgattgc aattgatccc ggtcattata ttgaatcgtt atgcaagcaa cgatttatcg
    24241 agaaatttga atcttggaaa caagaagaaa attgggatat taactttttc gtttctgaaa
    24301 caaatacaaa cccatttcaa tttaattaaa aggagagaat actatgtacg aaaatctttt
    24361 gccacgtttt ttacgatatg tcaaaacaga aacacgctcc gatgcaacaa gcaaaacgac
    24421 tccatcgact cagacacaag ttgcttttgc gcaagaattg aaaaaagaat tagaagagtt
    24481 aggcttagct gatgttttct ataatgaaga taacggattc gttatgggaa cattaccaag
    24541 caatgttgat catgaagtgc gttccattgg atttatttcc cacatggata cagcagattt
    24601 taatgcagta ggagtcaatc cacaaatcat tgaaaactat gatggcgagt ctacgatcgt
    24661 actagatgcg gaagaacgct atacattgaa tacaaaagat tttccaaatt tgaaaaatta
    24721 tgaaggccac acattgatca caacagatgg cagtacatta ctgggagcag atgacaaatc
    24781 agggattgcg gaaatcatga ctgcaatgga gatcttgatc aataatcctt ctatccctca
    24841 cggtaccatc aaagtggctt ttggtcctga tgaagaaatc ggtgtcggag cggataaatt
    24901 cgatgttgag caattcgatg tagattttgc ttatacagtc gatggtggtc ctttaggtga
    24961 gttgcagtat gaaacgttta gtgctgctca agcaaatatt acgatccaag ggaaaaatgt
    25021 acatccaggg acggcaaaag atacaatgat caatgctcta cagttagcaa tcgattttca
    25081 taatcagctt ccagccgatg aagttccaga aaaaacggaa ggatacgaag gtttcttcca
    25141 tttgatggca ttggatggga atcctgaaga agcttctatg agttatatca ttcgcgatca
    25201 tgatcgtgaa aaattcgaag cacgcaaagc acaaatcaca catatccaag aagagttgaa
    25261 tcagcgattt gatcaagaac gaatcaaagt agatatgtat gatcaatatt acaacatgaa
    25321 agaaatcatt gaaaaagata tgagcatcgt ggaattagcg aaacaagcaa tgatcgagct
    25381 tggtatctct ccagtgatcg aaccagttcg tggaggaaca gatggttcaa aaatctctta
    25441 catgggtatt ccgacgccaa atctatttgc cggaggagaa aatatgcacg gacgattcga
    25501 atttgtttct ttacaagtaa tggaaaaagc aacagacgtg attgtaaaaa ttgcagaatt
    25561 gaacacaaag agttaaaatc gaaaaagaac agcttatgac aaggcgttcg tcccaatgat
    25621 ggaatgtcat ctgtctaagg ctaaagggca ggacaatgga attggttgtc ccgccctctt
    25681 ttttgaagag taaataggag gtaaagaatg gaaaagctgc tagtttttta taacaaaagt
    25741 tcagggaaag atgagggtga gaaattagca cgctggtttc aagattatgt aaaagaaaag
    25801 cagccagaat tatatgtaga actagctgaa actggcccat cgattgatga tgcggaatta
    25861 gtcaagaaag cagaagccat agaagctgat actttagtaa ttataggtgg agacggcacg
    25921 attcatcata tcgtccaagc gttccaaaaa acattatctc aataccatgt cggattactt
    25981 ccaggtggaa ctgtcaacaa ccttgcacgt gttcttgaga ttcccctcaa aaaagaagaa
    26041 gctgctgacg tgatcctgga aggcaatgta cggaaaatag actatggtca agtcaatgat
    26101 gaagtcatta tctctacact gacaatcgga atcttagcag atacagcagt ttggatcagt
    26161 caagaagaaa aacagcgtta cggctcgtgg atctttatca agaagttttt taagttattg
    26221 ctgaagaaga aaaaatatca tttggattta gaaacagacg aggagcattg gaaaggaaaa
    26281 tcccaactgt tgacagtcac gatgtctaac tccgtgggcg gttttacaaa ttttgacgac
    26341 tcagcgaccc tagatgatgg aaaatttcat gtaacgatcg taccttcctt agatattttc
    26401 cgatttattt tttatttgcc tagaatcatg agaggcaaat tctatacgat ccccggcatt
    26461 acttatttca cagccaaacg catgaaaatc caagcgcagg aaaaatctgt gggcactcga
    26521 acggatggag acacgacaga tgatcttcca gttgaattat ctgttgtatc aaaaggatta
    26581 acagtttatt caccaaagaa agaagaaaaa gcttagaaat agtagttaac agaaagttgg
    26641 aagaagagta atggatgtat tgttacacaa tcctttgtgg ttttaccttt tcattgtgaa
    26701 tttttactta ttttgtctga tggggtatga taaacatcag gctagaacta gcggctggcg
    26761 tgttcctgag aataatttga tatttgtcag cctgttaggc ggtggtttgg gaggattgat
    26821 ctctcgaaaa gttttccatc ataaaactcg gaaaaagaag tttactatag gattcgctgc
    26881 aggtgtactt gttgatttga ttctcattta ttttttccat taaggagcag gagatgtcgt
    26941 ctaaaggaac gaaaactaaa atcattctga atctgctttt gctgattgtg atttttgcca
    27001 ttatttatta tttaatcaat caatcatttg cagatatctt tgccgaattg ctgtctacca
    27061 gtgttgttgt tttggcagcg gctgttatat tagggacagt ttaccaaatc gctgaagggc
    27121 gctcaatcaa agaaattgct gaacctttcg cgccgaattt tacaacgaaa gatgggttct
    27181 tgacctctag ctatattgcg ttttaccgaa tcgtttcgtt tggtacagga acgctgatct
    27241 cggagattta tttttataac aaaaaaggaa tgaagctatc ccagggagca ggggtgacag
    27301 cactccatat gattatgtac aaactggcag tgatcactta tgcattagct ggcttggtca
    27361 tccaattctc tcttttttat tctaatggtc catcaatgat ctggtttatc atcgctggta
    27421 tccttttgac gatcgtgatt gttgcctttt tattggcgat gtccgtcagc ttgaatgttc
    27481 aaatattttt tgtcagctta tcgaataagt tatttaaaag tgagcgtttg cggaaatggg
    27541 tggatacatg caatcagcag atctactctt taagggaaac ggtccaaacc attatccaag
    27601 acaggactgc gctattgcgg atttatctat ggaatatgtt aaaacttgta ttttggtatg
    27661 tacttcctta tttgattctg attgaaaacc atcctaaaat agattttcta ctgaccattt
    27721 cgtttatcag ctttgcagta gtgctttcag gggttattcc tacgcctgct ggtattggtt
    27781 cctttgaatt tgtctatttg ttattattca gaccagttgt tggaacagtt gacgcagttt
    27841 cttcgctttt actgtatcgt ttcagttcct ttatcttgcc atttctctat ggatttgtgt
    27901 atgtgattgc tgaacggcga agagtgatca aagaagaaat aatagaagta aaaaaagaga
    27961 ataaagaaaa tcaagggtag gtcttttata agatctaccc tttttatcaa atcaaagaaa
    28021 aacgttatgg ataagataat tttacgtttg tttg
//
LOCUS       DACDAF010000026        27860 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.026, whole genome shotgun sequence.
ACCESSION   DACDAF010000026 DACDAF010000000
VERSION     DACDAF010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.026"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(424..1368)
                     /locus_tag="IVZ69_001110"
     CDS             complement(424..1368)
                     /locus_tag="IVZ69_001110"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HAP8183213.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(1664..2608)
                     /locus_tag="IVZ69_001111"
     CDS             complement(1664..2608)
                     /locus_tag="IVZ69_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8183214.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            2829..4043
                     /locus_tag="IVZ69_001112"
     CDS             2829..4043
                     /locus_tag="IVZ69_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8183215.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            4065..6080
                     /locus_tag="IVZ69_001113"
     CDS             4065..6080
                     /locus_tag="IVZ69_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HAP8183216.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(6163..7536)
                     /locus_tag="IVZ69_001114"
     CDS             complement(6163..7536)
                     /locus_tag="IVZ69_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP8183217.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(7562..7846)
                     /locus_tag="IVZ69_001115"
     CDS             complement(7562..7846)
                     /locus_tag="IVZ69_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8183218.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(7848..9863)
                     /locus_tag="IVZ69_001116"
     CDS             complement(7848..9863)
                     /locus_tag="IVZ69_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HAP8183219.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(10042..10347)
                     /locus_tag="IVZ69_001117"
     CDS             complement(10042..10347)
                     /locus_tag="IVZ69_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HAP8183220.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(10436..11467)
                     /locus_tag="IVZ69_001118"
     CDS             complement(10436..11467)
                     /locus_tag="IVZ69_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAP8183221.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            11674..12549
                     /locus_tag="IVZ69_001119"
     CDS             11674..12549
                     /locus_tag="IVZ69_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP8183222.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(12701..13543)
                     /locus_tag="IVZ69_001120"
     CDS             complement(12701..13543)
                     /locus_tag="IVZ69_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP8183223.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(13635..15512)
                     /locus_tag="IVZ69_001121"
     CDS             complement(13635..15512)
                     /locus_tag="IVZ69_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP8183224.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVCNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(15509..16930)
                     /locus_tag="IVZ69_001122"
     CDS             complement(15509..16930)
                     /locus_tag="IVZ69_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP8183225.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(16933..20322)
                     /locus_tag="IVZ69_001123"
     CDS             complement(16933..20322)
                     /locus_tag="IVZ69_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP8183226.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            20579..21970
                     /locus_tag="IVZ69_001124"
     CDS             20579..21970
                     /locus_tag="IVZ69_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP8183227.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(22043..22690)
                     /locus_tag="IVZ69_001125"
     CDS             complement(22043..22690)
                     /locus_tag="IVZ69_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP8183228.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(22698..23384)
                     /locus_tag="IVZ69_001126"
     CDS             complement(22698..23384)
                     /locus_tag="IVZ69_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183229.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(23390..24463)
                     /locus_tag="IVZ69_001127"
     CDS             complement(23390..24463)
                     /locus_tag="IVZ69_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP8183230.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            24685..25359
                     /locus_tag="IVZ69_001128"
     CDS             24685..25359
                     /locus_tag="IVZ69_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8183231.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            25364..26704
                     /locus_tag="IVZ69_001129"
     CDS             25364..26704
                     /locus_tag="IVZ69_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP8183232.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(26853..27839)
                     /locus_tag="IVZ69_001130"
     CDS             complement(26853..27839)
                     /locus_tag="IVZ69_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HAP8183233.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
BASE COUNT         8130 a         5267 c         5044 g         9419 t
ORIGIN      
        1 aaaaatgata aacctctctc gaacggtttt ttatcaaaaa tcgtcatttt tccatcaaaa
       61 tctgcttatg caaaattata aaaaaatttt gcagtttttc ttactttttt tgtcgtttaa
      121 ttgaatgata aaaaccagtt tctttattca gttaatcaaa tatgaacgaa ttagatatga
      181 atcattgtat ttgccgttgc ggaaggattt tttaattaac cacagataaa cattgataac
      241 gattcgctta ttgtaatcaa cagattaaat ttcatatgtt catatgtacg gatacatttt
      301 cggaccgatt aattttaacc attctgttta tttgcttacc tattagatat caataaaaaa
      361 ctgcttaaca gctatttcag ctgttaagca gttttaggat ttttagttca tattcattgt
      421 ttcttataat acagtgttca atacttctct taaagcactt gttgatttgc tgaacattgc
      481 tttttcttct tcgttgattg ataattcaac aacttcacga acaccatttt cgtcaacgat
      541 tgatggcaca cctgtaaaga tatctttttc gtcgtattca ccagttaaat aagcagatac
      601 aggcaataca gcttgttcgt tattcaagat agcttttacg atacgtgcag tactcatacc
      661 aataccatag taagttgctt ttttacgatc aatgatctca taagcagcat tacggacttt
      721 atcagcaatc acatctaatt catcttgggc aatacgatgg tctttttcta caatttcaaa
      781 cactggttta ccaccgacag ttgtatgtga ccatgcagca acttctgaat caccatgttc
      841 acctaagata tagccgtgga cgctgcgtgg gtcaactttt aatttcaatg cgatttcttt
      901 acggaaacga gttgtatcca atgttgttcc agtaccgata acacgtgatg ttggcagacc
      961 agattcgttc caagcgatat atgtcaaaat atctactggg tttgaagcaa caacgataat
     1021 accgtcgaat cctgatccca tgatttcttt tacgatttgg cgcatgattg acgcatttgt
     1081 tttaactaaa tctaaacgag attgaccagg tttttggttg ataccagctg tgataacaac
     1141 gatatcagca tctttacatt cttcatagcc acctgaccat acagccacat tttcatcgcc
     1201 ccaagccata ccatctaaaa ggtccaatgc ttccccttct gctttttctt gattcacatc
     1261 gatcaatact aattcattag agattccttg gttgatcatt gcataagcga tacttgttcc
     1321 aacaaaacct gtaccgacga ttactacttt acgacttgtt tttttcatga ataaacagct
     1381 ccttttcata actatttgtt actttcatga aaagtatagt cttgtttatt cattttatca
     1441 acatgttaat tataatagtt gttattataa tttttgatgg aaacgaattc ctgaatacgc
     1501 ataacagata aatgacaaat gtttacacct atatcccctg ataatacaac caaaagttta
     1561 gaactgaaaa taaatccaaa aaaattcgct gcaacgatat aataagacag caatcgcacc
     1621 taaaacaatt ttccttcata tgctttagtg aaagattttc ttcttaatgt ttatttctcc
     1681 attcattggg agtacatgtt gaatacttct tgaataattt gaataaagaa gtcgtttgtt
     1741 tatatccgat acgattagcg atttcttcca acgaaaaact cgtttcttga atcagttcca
     1801 acgcaaagtc gaattttttc tttagaacca gttcttgaaa ggaagcatca aaatacattt
     1861 tcaatttatt actaagatag accggattgt agccaaaatg agctgctgtt tcttttaacg
     1921 tacaagaagt aaaatgctta tcgatataat ctaatactct aagcatctca ttttctgcgc
     1981 atccatctgc tgatgaaaag ctttgttgtt ctaataaatg agtcaattcg atcagtaata
     2041 gtgatgtata gagatttaac gaacggatct tatgactgta tgtatcaaaa taaatcaaca
     2101 gcatattttc aatcaaatgc gtcaaacgac ttgtttttcc gccgcgaaaa tgaatgaatt
     2161 gtgtatgttc ccctttttct tttgatgcat ttatcaaaaa agaagaaagt agattatttg
     2221 tgcttgccaa atgattcaat atctctgtag ataaggtttc ttcttttaat aagatgttga
     2281 ttaaaatatc ctcttgccct gtgtattcga ttctttgagt agcttcttta tcaatgatca
     2341 ccacgtcact ttcttccatc tctatccttt ctccattaat aatttgtaaa catgtaccgc
     2401 tatacatata attgatttca acaaaatcat gtgtatgctc gggaacttcc gcatatcgac
     2461 ggtgtttact gatatgaata tttccctgtt gaaatagatc ccctcggtgg atttttggcg
     2521 gtgtctgaag atggtaagct aagtttaaat cattgatatt cattccttgt tcacgctgca
     2581 gagtttcgat tgattcttcg ttacgcaaaa aaaatgtcta attcagctag ttccaattga
     2641 ctccctcctt tttgtaagcg gtttctttcg cttattagtt cacgctgtac tgctattata
     2701 tgcaaagcta tttttggttt cataaagact ttctatggtt gggacatgaa cttcctgtga
     2761 ttccgctatt gagagaataa ccacttcata ctatattttt gataagcgct tacaaaaatg
     2821 aaaggaacat gcttatgaat aaaaagatga tgaaattttc tctgctgtca gtctctctta
     2881 ttttgacttc tgctggtgca gtcacgtctg caattcccag tatgtcagct acttatgcca
     2941 cgcgttcttt atctgctgtt gaattattaa cgactgctcc ctcttttatg gtcactattt
     3001 ttgttttgat tagtagtttt attgctagga aaatcggaca aaaacaaact gtgatcatcg
     3061 gattagtgat tgcatcgatt tatggtatcc tccccctctt ctcacaaagt tacagtattg
     3121 tcttagcttc aagagctgga ctaggtattg gctttggatt gatcaattct ttggcagtca
     3181 gcatgattgc tgccttttat cacggagatg aacgagcctc tatgattggt tttcaaagtg
     3241 catttcaagg atttggtgca gctttaatga catttgttgc aggacagcta gtacagttcg
     3301 gttggcaata taccttttta gtctacgcca tcagcttacc tattcttgtc ttgtttgttt
     3361 tgtttgttcc tacacctgaa acaactgaac ttcaatcaca tggcacagcc ccaacaagac
     3421 aagtaatcaa aacgaatcct aaaatgatta gttatggtat ttttctcttg ctggtcatcg
     3481 tggtatataa tgctgtatcg attaaattag ccacagtcct gacgacttat tctctaggaa
     3541 acgaaactaa tgcagcgaat atcttaacaa tcatgcaatt ggcaagtatg gctgccggag
     3601 tttgttttgg ctggcttcag acaaaagcac atcgctatat gcttacactt tctttactac
     3661 tgatgggaat cggctttgta ttgattgcca ctgtgataaa cctgtatgtg attgggtttg
     3721 gtgcgatcct aacaggaatt tctttttcgt tattcattcc ttacttattc aaccaagtaa
     3781 gtatccaagc gcccaagtac gcggagagtt tcaatacttc aatcttattg gttggcgcta
     3841 atttaggtac tttcattgca ccatatggtt tgctctttct ctcttttgct tctcttggga
     3901 gtaaaacact tgctgttttc gtcaatggca gtatcttgct gttgattagc gcgcttatta
     3961 gccttctagt agtacacagg acgaatagaa agacagtgat aagagtagat gaagaaataa
     4021 aagaacaatt gacaacaaaa taaatttgat ggaggtcgtg taaaatgaca aatgaaaaac
     4081 ataaagatag atggctttgg tatcctggag actttgagat ccgccatgga ctgctacaaa
     4141 atttccaacg ggaagaacga ggttttgact ggccagcgta ctggtacatg gatgattgcc
     4201 atcggaacgt caagtttaag agatattact ttcttgatca accttccatg tttaaagtga
     4261 cgatccaagg agttgggtat gtagaaatta atggacaaaa acatccatgt ggaaaatggc
     4321 tgacttgtcc agctggtaaa gcaaaaattc gtatctttgt aggacataca tcagggctac
     4381 cagcgatgtt tatcgaggga gacgaagtaa aatcagatat tggctggaca gcaagtaatt
     4441 ttattgaaga atatccagct ggctggagtc cgctttatgt cgatatcgca aaagatccaa
     4501 atcaaatcta ttatcaaaaa gaatgcgtcc atccagtcac tgaaacggag attggcggag
     4561 gaatcttatt cgattttggg cgagcagtga atggctgtgt agaactaata tctctggatg
     4621 accatatcga atctatcact ctatgttatg gagagtccga tgtagaagct atggatatcg
     4681 attattgcta ctataagcaa ataggaatga caagaaaaat gaaagctcgt aaacgcgctt
     4741 ttcgctattt gtttatacca gaggtttcta ctggaatggt tcaacttcaa gtttttcatg
     4801 aatttttatc tctttcgaaa caagctgctt tttcaagcga ttcttcttta ctgaatcaga
     4861 tctggtcagt atcagaagaa accttcaagt tatgtagtga tttgtttttt atcgacggta
     4921 tcaaacgaga tcgctggatt tggtctggag atgcgtatca atcattcatg atcaatcaat
     4981 atcttttttt tgacgaggaa atcaataaac gaacgatatt agcattaaga ggacaaaatg
     5041 aaatcaagca gcatatgaat actatcgttg actattcgat cttgtggttg attggtatcg
     5101 aaaaccacta tatgatgacg aaagactatg aatttttacg catcgtctac cctaagatgc
     5161 aatcattaat gagatacttg atggagcaaa cgaatgaatt agggtttatt tatgggagag
     5221 caaaagattg gatatttatt gattggtctg aaatggataa agaaggaacg cttgctgcag
     5281 aacaagtctt attactgaaa gcctatcatt ccatgatcac ttgcggagat atcttagctg
     5341 aaacatatgg agagaacgaa aattatcata ctcatctcta tcaagaaaaa tatcaactat
     5401 tgaaacaaaa cctatttgac tacttttggg atgaagaact tggcgctttt atcgattgct
     5461 atgaatctgg gagaagaaat gtgacgcgtc atgcgaatat tttcgctgtt ttattcgatt
     5521 ttgctaacaa agaccaacag caatcgatct taaagaatgt cttattgaat gacactatca
     5581 cacagattac tactccatat ttcaaattct atgaacaaga tgctttatgc aaactcggac
     5641 agacgaatat cgtctaccaa acgattcttg attattgggg agggatgtta tctcatgatg
     5701 cggtaacttt ctgggaagaa tacgacccta ctcaaacagg aaatgaaaag tacagtatgt
     5761 atggagatcc ttatggaaaa agcttatgcc atgcatgggg agcaagccca atctatcttt
     5821 taggacgcta ttttatcggt ttgtatccaa caaagccagg ttatgaagaa tttatgatac
     5881 aacctaatct agattcattt gaaacactga attgtacgct acctatcaaa gatggaaaga
     5941 tttcgcttga aaaaacaaaa gataagatcg tgattacttc tgatagaaca ggcggaacag
     6001 tgaaaatgaa tggtaaaagt tatcctcttc tagcaaaaca gccacttgtc ttaacaagct
     6061 attcaaaaat aaatgcataa aacaaaaaac tgcttgcgac atatcagaag actttaaatc
     6121 ttcttctgat attgtccaag caatttttat tttgaagttt gcttaattct gttctttaga
     6181 aacaatgttt gttctttttc cggcaaaaag aaagctagat aatacgacaa gtaaaaagaa
     6241 agcgatgatt ccaactgtca aggctatttg accgtattct cctagtttcc caagtacaag
     6301 tcctggtact agataatcag tatcggcaaa tgtagaagaa gcgattttaa gatctcctaa
     6361 tactggaagg ataaataatg gcagccaact aatcaataag ctattgaaag cagaacctaa
     6421 taccgcccct cttctaccgc cagtcgagtt gccgaagaca ccagaagcag ctccgcagaa
     6481 gaaatgtcct actaccccag gaatgataac tgtagtttgc aagcctatca tagcaaacat
     6541 ggatagtgtt cctacaaaga agctaacaaa aaagccaatt aatacagcat taggtgcata
     6601 tggaaaaacg ataggaacat ctaatgctgg tttagaatcg ggtacgagtt ttttagcaat
     6661 cccttggaat gctggaacga tttctgccaa caccattcga accccttgaa ggacgataac
     6721 aaacccagct gtgaatgttc cagcttggat cagtgcaaag attacagcgt tgtctccatt
     6781 gcttagttct ctttcaacaa atccaggacc agctaacaaa gcaagtgcga catatacgat
     6841 cgacatcaag agcatgatcg atacagtaga atctcgcaaa aagctgaaac ttttaggaat
     6901 ctttatgtcc tctgtagaac ggtctttgtt tccaaaaaac tttccgatcc atccactaga
     6961 agcataaccg atatttccgg tatgccctaa cgcaacttga ttgtttccag tgatgttctt
     7021 cataaacggt tgacaaagag caggcgtaat agttaatagt gttccttcga agaccccgcc
     7081 taataagatc atccacaaat ttgcagtaaa ccccgcgctt actaaaatga ctgctgttag
     7141 acaagaaaca taaagcattg cttgacctgt aagaaaaatg aatttatatc ttgtgaatct
     7201 agcaagtaaa atattcacga tcatccctac tagcatgatc aaagcagtag gtgtaccgta
     7261 ttgttgcaaa gcaatcgcca ctactgcttc attgctagga actactcctt gagtatgcag
     7321 agctgtttgg aacatcgaag caaaaggggt tagtgaatta ctgattaaac cagcaccgcc
     7381 gatcagtact aggaatccga caaatgtttt gatagttcct tggatcactt ctgaaaattt
     7441 cttcttctga agaacgagac caagcagtgc aatcaaagaa acgaggatgg agggctgact
     7501 gacgattgac acaaacaaat tcaacaattt atccattgat agttcctccc ttgaatcatt
     7561 tttattcttt tgacaagatc ttcgttactt tttcttttac ttcttcgctg tcaatgatcg
     7621 attgcaaagg tacgagcttt tcatcaggta tagaagttag cgtatctttc aaagaatgct
     7681 caatgaagaa ataatcagcc atatcgctag atacacttcc aacatccgta tgacttactt
     7741 caaactcgtc cacatctgct ccaagatctg caagtgcttg tttgatgttc atctctacca
     7801 taaaacttgt tcctaatcca ctttgacata ctgcaaaaat tttcatatca ttcgtctcct
     7861 tttcttatga tcgctaatat ttcttctttt gttgatgcgt gtaataaatc ttgaagattt
     7921 tgtttattag aaagtagctt tgttaaattt gccaaagccc gaagatgtgc ctcattatcg
     7981 atagcagcta aacagatgaa caaactaatg ggatgggctg gattatcaag cagatccaca
     8041 ggttgttgaa gtttcagcaa agacatccct acttcgttta cgccatcttc tggacgagca
     8101 tgaggtaatg cgatgtgatc gccaatatgg ataaacgcac catactgctc cacgcgctcg
     8161 atcatagctt tgatataact ttcttctatt ttattttctg ataatagcgg ctgtgcggca
     8221 aatgtgattg cttcttgcca gttttttggt tgatccgata attggatcat ttcttctgtt
     8281 aataattcag atagcatagg acgttgatcc tccttctttt ctaaaagttt gttcatttta
     8341 cgatttaata cttgatagag cttttcttcg tctacgcctt cttttaattc gatataaggc
     8401 agtagcgccg acaacaattc ttgggcagaa ggcattgaaa atcctggtat cagccaatct
     8461 ctttgtactt gattgatcag ctgatttttt tccaagtcag tcatgattgg atgcagaaca
     8521 tagagagact ttttcttatc agtaagtgtg agaggtacag tagaaaaaat aatatcgtaa
     8581 gaagtttcgt caacctcgtg taagcggtca gctgaattag tctctgtaaa aaagatcatc
     8641 gggaataatt gctgaagttc actttttaag atcaatgaag agctaatgcc acttggacag
     8701 acgatcacgg ctcttatttt tctatttctt tcttctgcgt ccgcttttct gatctctccg
     8761 ccaaatagta tagtgaaaaa accaatctct tcttcaggga tgctcttccc tattcgtctt
     8821 tctaacggaa gtaatgcttt tcttgtcatt tcgtagatgg aagcatattg atgcttaatt
     8881 tgatcgatca tcacattagg taaataaaaa gaataggaaa tacgaaaata ggcagggacc
     8941 aagtgataaa agacattcat caataattca cgaaacgaag caaattctac ggccatcagg
     9001 aattccatgc gatggatgac ttctgaagaa cattccagca aaaaatcaag tgcaggctcc
     9061 tggacatctc cttcaacgat cgatgctaag caaagagaga aaaatataat ctccgaattt
     9121 tgatgttcgg aatagccaag gccagtcaat acttgtcgac taatgtcagt gactgcaaga
     9181 gaagccaaca gttcagcatc ttttaccagt tccatggatg tttttccaat tcgaatggtt
     9241 gtcaaactca aataataagc taattcatcc attcgatttg gtgcgaatcg aagatctgat
     9301 agtgaaatcg ttttatctag caaatctcta actttggcgt aataatcaat ggaaagggtt
     9361 gcggttaaat acgtgagccc aaatcttcca gcaagtgact gcatcaaacg agcagtgcga
     9421 ttttttgctt ctcttcttaa tattgcttct gaccctagca gcctaaaacc agttttccta
     9481 gtatacgaca gctgacaatc ttccacttct aattcatttc ttatcttttt gatatctgac
     9541 aggactgtcc ctttagaaac ctgaagaaaa tcttgaaaat gaaaaacaga aacagacgtt
     9601 gcagtcgaat aaaccatcaa ataaagaaga tctcttcgct cttgttcggt atacacagct
     9661 tcaaatcgag taatatccaa aaatttttct gcccagtcga ttgctcggaa tttctttata
     9721 cggatacggg tatcatccac atattcggca aaaggagtta attgtttgat cgcctcgctt
     9781 gtatttactt cgatgatctc tgctgctttt tctagactga tttctcttgg tgttttcagg
     9841 agataactaa ttttgtagtt cacagcgctg ttcacctcct acttatattc tagtatggta
     9901 gcgcttttaa atcgaggggt gtttggtaca acttacagtt ggattttttt tacgactgta
     9961 ccgaacgatt tctatcgaat ggatacagaa aaaaagcagg tgaccaaatg tctcctgctt
    10021 ttatgaattg atttcgtccg atcaatgatg atcatgttta ttttttgagg tcagttcttc
    10081 aaatttttct ttgacatctt caaccgcttt ttcgatatct ttttcaaagt gattgggctc
    10141 attaggcttt gtttcctctt ctacagaatt tgaaccagat aaagctgttt ctttattttc
    10201 tgtttcacca gagtttgtgc cagctaatga ttcttctttg tcttctgttt caccagaatt
    10261 agttcctgct aaagccactt cttcttctgt tttaggggcc attgaacctc ttaatcgttt
    10321 gtgtttttca ccgtcataat ttgtcatgtt ggttcctcct agtagttcta tactttttca
    10381 tcgtacaata agacagttta tgcgtcaaaa aacaaacccg attcttacaa atatgtcata
    10441 tttttccttc tgattcttga atgcttttga ttccttcttc caaaattttc atttgtaaga
    10501 ttgtttcttc atctttgatg actttttctg cgccattaac taatgtctcg taaatccctt
    10561 cgtagacacg gctgtaatca ccaacctcgg aaattacttt ttcttcatga taactccctt
    10621 gttcatctat ataggtcaat acaccataat gttcgggcaa atcgatacca aagtcttcat
    10681 gatcaggcat gtaaaacatt ttcagatgtt cttcttgtcg atcttttgtt tgtttcacga
    10741 acatcccttt ttttccgtaa acgacgaaac ttggacgttc tttgatgcgg aaataactgg
    10801 attttatcga aattttcata tttccataga aaaaatccag atcgaagtaa tcattcattc
    10861 gtcctttccc taaaagttga cgtacatcat agctgatatc atctggttcg ccgaaataag
    10921 aaagaacttg atctactgta tgacaagcat gtccatataa atagctgttc gcagtagaaa
    10981 attcatgcgt attttctggt acttccggtc tgaaataatc ataatgcatt tctacttcta
    11041 aaatatcccc taattttccg ctttcgatta ctttttggac tgtcaagaag tcagaatcga
    11101 accgtctgtt ttggtaacat tggataaata gacctttttc ttttgctaat gcaaataact
    11161 cttctgcttc ctttgacgtt tctgcaaaag gtttctctac tagtacattc ttaccatgtt
    11221 cgagtgccat ttttccatat tcataatgaa attgactagg tgtagtgatg acaactaatt
    11281 ggatctcagg atcatcccaa agatcagaca gctgatcagt atattcgatg tcttcgaatg
    11341 ttttccacac tggttcagat ggggaaaaaa tttttttgat attgattttg ttcgtaagtt
    11401 ttcttgaaaa aggcaaatga tagcgatttg tactctttcc attgccaaga taagcgattg
    11461 taagcatgag tggtgcctcc ttttattgat gttttcagta tatcctagaa aagcgcagaa
    11521 agtatttata atagctattc tggtaaaaaa gttcagaaaa acacttgtta tcattcggtt
    11581 tggtgaaatt aatgttcaaa gtaaggataa aaatcaaaaa gatagtagcg gaaccaagtg
    11641 tttatcagta agatagaatt tggaggtcag atcatgctta ttgaagaaaa actaacaaaa
    11701 caagagttgt ttaccacgac agagaaacgg attgtcgatt acatccgtag gaatatcgaa
    11761 gctgcagtct acatgacgat tgaagaatta gcaaaagcta cgtatacttc ccattcagct
    11821 atcattcgtt tatgcaaaaa aatgggattc agcggattta aagaattccg tttcgagctg
    11881 gggcgggaag ttcatcaatt gattgctcag ttcaatcaaa cgattgatcc taattttcct
    11941 ttttcaagtg aagatagcac tcagcaaatt gcaaagaaaa tggcggattt atcgatccag
    12001 tcaataaaaa aagcacaatt gcagattgaa catgaagatt tagatcaaat cggtaaagta
    12061 ttgaacaagg cacagcgaat ctttcttttt gcaaaaggtg attctcaaat cacggcaagg
    12121 aaattccaga ataaaatggt caagttgaat aagtttttga tcatggctga agaatacagt
    12181 gattcttctt ggaatgcagc caatttgact agcgaggatt gcgccatttt tattagctac
    12241 agcggtcgca tccatcatta tgaacgaata atgacctatt tgaagcatgt agaggcccct
    12301 accttgctga ttaccggaaa tcagcattca gaaatggcca aacaggctga tatgtgtctt
    12361 gttatatcgc aggaggaata tgattttgct aaagtagcga ctttctcctc tcaaattgcc
    12421 ttcgattacg tattaaatac gttattctca gtgatatatt ctcaaaattt tgaagagaat
    12481 atccgcaact tgaaaaacaa acaagaattg atgcaaaaag gccttcttaa agaatatcgg
    12541 aaaacttaag aaaagatcct catttagtaa taagaaagat agtgtttgat aggctctctt
    12601 tgatatcatc ataaaaacag gctgaagttt tctttttcaa acctcagcct gtttgtttac
    12661 ggaacgattc gaatagatat attatagaaa tgaggaatag ctaacttctg tttcttattt
    12721 tgaacgattg acgaaaaaga tatataagaa ggaggaaaat cagtatacat gcagctaaca
    12781 atccatacag gaaaaatcgt ttgttctcgg atactttctg tacttctttt tgaacttctt
    12841 ttgcatgata aggaacccgg tgccctctga caagtaagcg atgactgttg accatataag
    12901 gtgtacaagt taggagtgtc acgaaatcct gccctttttc gattctcaga tcttttgtat
    12961 cagtcggttc taccgtcttg atctgatcga cttgataagc gagtgtccgt ccattgattt
    13021 cgatatagaa agaatcacct aaagtcagtt tcggtaagtc tgtgaacaac tttgcttgag
    13081 gcagtcctcg atggctggaa ataacggcat gtgtattttc tccccccgta ggataagacg
    13141 ttccttccaa taatgaggca cctttttcta gcagcacagt attcgtttca tcaaaaattg
    13201 gcaaatggac attgatctca gggatcgtca aaataccgat cgtatgtttc tcaaaatagg
    13261 ttctatcctt tttcgcaggt tcttttttct tagtaaaggg atctgcacct ggatttccac
    13321 cttcttttgc taattgctgg tttttctttg tcatgttttc ttggatttta gccatgactt
    13381 cttcattttc tttgaccgct tgttgctgat aatgagagat gatctgctga tccagataat
    13441 tattcagcgc gtcgctaaca aatggataag ctagtatccc tattcctgag agaagcaaga
    13501 aaagcatcag cagatctaga agtttccttt tctttggttt catttgtgtt ctccttgtga
    13561 tgactgtttg ataataaaag aaaaaggagc atttgcgtaa tccgctgctc ctttttccaa
    13621 ttcttgcaaa aagactaaat ctgactgtgc ttgcgtctag caaagtacag tccagcaatc
    13681 agtagaagga ctactcctgc accgatatac acatagattc ccttaccgcc tgttgaagga
    13741 agtgtacctt tgtgtttatt tggtattttt tcaggagaaa tcaactgtcc tgctgttaca
    13801 taagattgtt catcgatagt aaatgctaca cggtttgtta atggaacata tttttctggc
    13861 gctttcgttt cttccagata gtacgtgcca tattttagac ctgtcacatc gattaaaccg
    13921 ttacttgtgg ttgtaaaaac cgttgctgat tctttcgccg atacccagct gacggctttt
    13981 gtggatgggt cgatcgataa atatttcgct gtgtcactat cttgatcacg aacgacgaat
    14041 tctgctccag caagtgtttg gtctgatgta acgtcaccat ctactttaac aaatcgtttg
    14101 cccccagtaa cgacatcgac tgacggtggt gtttgatcat ttgtatgccc gttatcgaca
    14161 tttgcttggt tagaaaatcc tttggttgga tctgcttttt cgttcaaatg catatagtaa
    14221 acgaatttca atgtaccgcc aggagttaat gaaggaatat aattcggatc aactgaaacc
    14281 gtgaatccgt ctgtttgctc agtgacagaa taatttactg ggtcgatttc tttatttcca
    14341 tcatataagg cataagcata cgttcctgaa gaatcattat caaatgttaa agcagcgtca
    14401 tgagtatcga taagtttgaa tgttgtgtac ttgttttgcg ttccttcttt atcagcgata
    14461 cctaatggga tattgacaga aatctcatat tgaatttttt caccgattgc gacatctttt
    14521 ccattcaatt gaggtgttgt tttatcaact ttagacgtat catttttgat ggtcttttct
    14581 actggtgttt ggctatttgc caggatctca aaaggcgtga ttgtttgctt ttcaatcatt
    14641 tccgcattat caggagcttt tacttcttct aaattatatt ttccaacttc taaatgatta
    14701 acgatcaact ggcctttttc aatagatgcc tcggcaaagt cattgttgcc gatgtcataa
    14761 gaatgaccag taatgaaatg tttggctttg gtttgatcag ttgtccaagt gtacaatcca
    14821 tctgtgacac tttggatgta ttttttgacg cttggtgttc cttcttcttt agaaataata
    14881 aattctgctc catttagtgc ttcgttttcg gcagtaccga tttttgtaac tttcaacgtt
    14941 ccatcattac agactgtatt tttagggtag agatggatag tatctagttc ttctgtcccg
    15001 tatttataag agccatctgc ttgtttgatc atctcatata cagggaaagc taaaaccatg
    15061 tttgcggcag ctgacactcc gtcttttggt tcttctttga tcgtgtagac tgcatctttc
    15121 ccattttgtt ttttaggtaa agataaagtg acatttccat cagcatctgt cgttcctgaa
    15181 gcaactggtg taccaggagt caaagactgg actgcttgtt ttgctgcatc cacggacgct
    15241 cctttatctc gttgcgcata aaattcttga gtgacgttat aaactgaaaa tgaaatatcg
    15301 gctaatcctt ggtattgatc gaattcgctc atttctttcc cgctgttttg gattaaagga
    15361 tcgggtaaat cagtcatttt ctttttatga aggatgactt gagctgctgt ctcctctgca
    15421 aacacttttt ttgcgccgaa gctgtttgtg agtaatggta aaataaggaa aaggactcct
    15481 aacataacgt ttattttttt atgatttttc attttttcac tcctgttctt tttttgataa
    15541 acaaccagat tgcaaagctt gcgaatacca taccaacaac gcctaaaagt gtatttttcg
    15601 tttcgtttgt ttttggaaga aatggacggc tattttcttt tttattgact actttcaata
    15661 tactgtccgc ctctttatcc tcagaaagaa aagttgaaat ggtaaacgga atttctgttt
    15721 cacttaaaat ataaccagaa ggtgcttcga tctcttttaa tcgataactt cctgttttca
    15781 acccggaaat tgaaaaagcg ccatttttat cggaaatcag gtgaagcgca tctgattcgt
    15841 tctttgtcca cttgtatccg ttggctgttt gctggaggta atttcctgct ttgtttttaa
    15901 taaggaatac tgcgccagct aatcgtttat ctggtttatt tgtctcgatt ttgacaaatt
    15961 gcttactccc tgtatataca gagactttct ttgtactgac accaaaacca aaatccagtg
    16021 ttccgttgtt gttgatttcc ttgttcgcct gtgctgtact gcttagctgc atctgataag
    16081 aaatggtcag tttttttcca gcatattttt ccaacgaagg gatcgaaaat aaaacatcaa
    16141 atccgtgagg tttcttgtgt atgacaaagc cttctgtcag cttttctcca ttcgatgaaa
    16201 tcgttaaact attaggtaaa aacgttaatg cttcatccgc actatctgac aattcgaact
    16261 tttgatagtc aaggatattt acaggaattg tcgtatgcaa ggaataagtg attttttcac
    16321 caatcgtaaa atcatttcta ggctcttcta ataccttctc aaaaggtgga tcagggtagt
    16381 cgttttcttc atttttagga tacaaatgga tagttgaaag tttttgattg ttttgtccat
    16441 gtacaggaag aacaactacc atattctctg ccttttcttt gacgacttct ggtactttgg
    16501 attcaatgaa aagatacgct ttatctcttt tttcttgatc tttagcggcc agagaaaaag
    16561 aagcgatacc atcttcgttg ttaagagttg tagttgttgc ttctgcggta aacataccgg
    16621 aagacgcacc gttttttgcg atctctgctt gtgcttcttc taccgttttg cccttttccc
    16681 gtagatggta aaaagaatct gtgacatcat aaacttggaa tgtgacacca tttaatcctc
    16741 gatacgtttg taataaagct ttttcttgtc cgtcatttgg atgatttttc ggcagttgcc
    16801 cgtttgggaa aagcaatttg tgtaaagtaa tctgaaccat ttctgtttct gtttctgttg
    16861 ctacctgagt aaaagctggt ttaaatagta acaagaagag acacatacta agccaaccaa
    16921 gttttttcat atttagctgc cccctctttc ttttttcaaa aaaagatacc aaatagaaaa
    16981 cgcacaacca atcatcccta ctagatagat tcctaaacgg ccaattcctc ccgtttcagg
    17041 taatggtact tttgcctgat tcgtgatgtc taaagaaatc tggttgtttt tggctcctgg
    17101 tgacagaaca gattcatgat cttgtccatc cacttgaatt gacccatctt cgtgtataac
    17161 tatagtaact ggctctttta gaccttggta tccttctggt gtaaaagttt cggtcagcgt
    17221 ataagttcca ggttttaaat tttcgaatag aaaggtatct gtttcttgtc catcttttgg
    17281 cgattctaag tccatttctg gtccctgcag tctgaatttt gctcctttta atgtctgtcc
    17341 gttgtcttct tttttgtgta ccgttagatc aaacgctttt agtcgatttt gatgagtgag
    17401 cgtccataca ttatttgtca tctcggtatt ttttcccgtg taaatgattt ttccatattt
    17461 atcgatttgg aattcataat ttcccggcga agtatcatat ccggcaggac cagctgtttc
    17521 aacgactcga tatttaccag gtgtgagtga atcaaaactg gcaagacctt tttcattcgt
    17581 tgtttggctg tcaattggct gataagtacc atttgcttct tttttctgta gggaaaatgc
    17641 tgctccttta agatttatct ctttgtccgt cccttgcatc gcatacttac gtactgctac
    17701 aggaacttca acaaaaggat tttcaatagt caactggatc gtatcatcgg aagtagtgac
    17761 tgtttttcca tcaatggtta ccgtaccatc agaagcgatc ttgatttccc aagtagtctt
    17821 tttgcttaat ccatgccctt ctggagcttt tgtttctgtc agcgtatagg tcatttcttt
    17881 ttgcaatttg acattttctg gaagagaata ggttccgtcg ccatgatctg ttagtaaagt
    17941 atcaatagaa tctcctgtta atttgaaaac agcgccaata agatcctttt cacctgtaga
    18001 ggaatttttc gttattttca agtttaacgg tgtgaattgt ttagtatttt tccatgtcat
    18061 tgcatctatt tgttgagaat cgtatcctgg tacaggtaat tctttgattg tttggtaact
    18121 gaatgcttga ccttgattat tgtattgagg tagtgataat atctcttgat aactttctcc
    18181 gctatttgca gataatttgt caatgtctgc acgttcccac gtatttgttg tatctttagc
    18241 tggtttaatg attcgaatat atccgttttt ccaagctgca gcatttgtcg tatgttcccg
    18301 ttgaatctca aaagtaactt gatctggacg atcagctaga ttgttgtcaa attcttccca
    18361 taactttttg atgtgaagac tgactccggg agctttagca gatggtatac cgaattcagc
    18421 taattcattg gtatcaatgt ttggctggaa agttgtcctg ccgttcattt gataccagaa
    18481 atttggatgg aagtcctcat tttctgtttg gattctcact tggtaatgga tttggatttc
    18541 ttggtctttt cctaaataga tctgattgct cttgatggta tttccttcta tggaaataga
    18601 tggagtgacc gttgtaggac ttgtccccac actcttgact gaaagtgtac caggctgata
    18661 aatgaatggt tctgcgattg gatcatttat ttgtccattg cttacagttg ctgagatctg
    18721 tacagctttt ttggctaggt attcagagat atctgttgca tgatcagctg attcatagta
    18781 aagatcgcct ttttcatctg atgaaaccat ttgtcgcata cgagactcta cttctgcttt
    18841 tgagagacca gctgccggat cgctttgaag ttggatgcca agaccatgta tttcgattcc
    18901 tcgttctttg agtgccatcg cttctccgat ggttgcgata aacgtactgt cgattcttct
    18961 ggatagattg ttttggtcag gtgcatcata gattcttgag attagagaag tatttcccgg
    19021 ccgatcttgc gtattagaaa actgagttcc gtaataattg ctgcttgatt gtgcgtgtac
    19081 ccgctgtact ttataggaaa atgttggtac accatccgtc agcaaaacga tcactttttt
    19141 atgtccattt ggaacggata gcatgcttcc tgcatctctt agtgcttttt gtgtaaaagt
    19201 accaccattt gtccgtgaag gtgtaatgga ttttacttga tttttcactg aatcaaatga
    19261 acccatctgt actgcaccgt tactgtagct atatccttcg cttgagtagc cgacatatcc
    19321 catattgatt ttgtctgtga taccgctatc tgctaaagta tcgacaaaac gatcgacacc
    19381 aatctttact tcaccgatcc gattattgtc gttcatactt cctgaccagt ctacgaccaa
    19441 tacgagatca agaggcgtga tatctttttg tacatttcca cgagcattca aataaacatc
    19501 aaacaatccg ggtgtacttg tttcctttgc atactttcgt atcgcatagt ctgcttgatt
    19561 accggttcct ccatattcga tatacgaatg ggtccgatca ttaggatctc cattccaaga
    19621 atttatacca tcccattgat ttgttccgtt tttattgcct tgatgatcaa gaacatttgt
    19681 atttcctgta ggttgccaac tggctttagg ataagtgccc tgatcatctg ttgtatattc
    19741 tgtaggaatc gtttgattag atggcacact cacagctggc aaggataatg taggcaatgt
    19801 aaatgggctg acagaatttt cgttttcttt tgatgattct tcttctattt cgtctggctt
    19861 tggtactgac acatctgtat ctttcttatt ttctgtctca tcaataatgt catattcttt
    19921 attatcgacg atcagcttgt ttgcctggct gtggtaaagt gctggatcga ttggaaaact
    19981 cagatcgata gtttgtttag tgtttgatga gatttccaac gtaattttcc cgctatttac
    20041 ctgataagca tagccatctc cttcttttct ttccacatca cttaagtaat tttcgactag
    20101 accaatttct ttttctatct tttcagcact ggtgttattc gcatttagct tgatgttcag
    20161 tgcttttttt ccagactgat ccgaaatgac ttcagctgaa attgtttcta aaactgttgg
    20221 atcatctgta gtgtctgcta ttgcagataa tggcacaaag tttgataaac tcaatattat
    20281 cagcatgaaa ataactttca gtttcttccc tgtggtcgtc atttttcccc tcctttttct
    20341 ttttttctgt tttgacgtga atagtgaaaa ttattaaaat aaacaggcgt tacataattt
    20401 tatttatttt aatatgataa ttattatacg aagggcgcta aagggaatca caccaatttt
    20461 cataccaatt ggtttcattt atgaagttga ttccttcgat taatgagcgt ttcattgaaa
    20521 gaaaagggtt gagggagaaa aacatatgat caggttgttg gaatgcaact atagaaagat
    20581 ggaaaaaatc attcgaattc tgtccatttc tgacaagtgg atgactaaaa aagaacttgc
    20641 caaacgaatt ggtagttcag aatctacatt tgtaaggtat atcgaagaga tcaaaatccg
    20701 ctggggaacg gatgtaacga ttcaatcttc acaaaaattg gggtatcgtc ttgaacattt
    20761 gaatgtacca gcttatttaa atgttctgat ggaaatgtcg caaagttcta caaacagtcg
    20821 tttattaaat gagattattg tcaatccggg taaaacgatt gagtattatt gtgaaaaaat
    20881 ttccatcagc cggtcttctt ttacacgtaa gttgaaacaa tgcaatcaaa ttttagaaag
    20941 ctatttatta aaagtgatcg ttgaccaagg ttttcagtta actagcctta aaagtgagct
    21001 ccagttgcgt atctttgtta cctttttctt tttaagttac tacggaagac gcacgttgcc
    21061 atttccaatc gaaaaaaaga agatcaaaga aattatggtc aagaataatt gtcagatgaa
    21121 tttgtttcag gaagaaagcc catatgagca atctttcttt attatgtatt ttgttgtgca
    21181 tctcatgaga gaatcccaag gaactccatt tgaatggaaa gctggagact cttatgtaca
    21241 gttgataaat atcgataaaa aagacttctt aatcttgaaa aatctcttag gaaaattgaa
    21301 gtacagcagc tatataaaag tagtgaacta ttttgtcaat acgatttttt cagaattttc
    21361 ggagaaagaa aaaaatgaaa tcagtgagca gatacgaaaa aatatgtcct actgttcgtt
    21421 ttcatccgct gattgcaaag aaaaaaacga agaatatgtt gttcaattat taacgcaaat
    21481 ttattttttc tcccgtattt tcccatacga tacgactcat ttgacgatcc gtgcaactta
    21541 ctttgcacag cagatgcaac accgccagat acgtctatat gctggatttc gtgcagaact
    21601 tcaattttat tccactctac tgaatcagaa tctgatttat tatttatcta gctatatctt
    21661 ttggatgctt atcggtaatc ctgaaattca ccattatact tctgataaaa aaatactgat
    21721 tatcagcgac ttaagtcttc gacatagtca atatattgaa gaatatatca gtgatattct
    21781 tgctgtgcat aaaattcact ctgagacaac tgctattact gaagatcagc tgtcgaaata
    21841 caatcttctc gagtatgatc tgatcgttac gaatcaaccc attttgaatg cccatgttcc
    21901 tcatatattg attgatgata gtgtgtcatt cgcaaatgaa gaagaactca tccgcttatt
    21961 cgagttatga ataatcaaaa aacagctatg tataaaccac cctgataaaa atttcaggac
    22021 aaatacacat agctgtttct ttttattgta ttccttcagc aatccaacga gatttatagc
    22081 gaaagtcttt taacaactct tcttttgtcc aattatttgc aatgagatcc gtcaaagtgt
    22141 tcattacgag ggtcatggaa aagtatagga aactaactgc ttcttccgac gattgaatgg
    22201 agaaatgatt gattcttaat aattccagcc atttttcgtt cattggagaa tcagccgata
    22261 gttctctacg tttggttgtc tgctgatcat ttcgctgggt taacaagtat aacctttgcc
    22321 aatagatact ttcgtgatct aagtcgcagc accactctaa atatttttcg atccccaaaa
    22381 agaaatgttg tttgttttcg ctaatgaatt ttaagatatc ttgatggact atgtgagaac
    22441 tgcttttgat cgtatacaaa taagcatctt ccaaatcttg aaaatattta taaaaagcac
    22501 cgcgcgacat ccccatcttg tcaacgattt ctgagacttt gacttggctg atgtgctgtg
    22561 agcaaaatat ctccagtaat aggtcatcga ttctctgttt ctttgcgttc gataaattga
    22621 aaaaagtttc ttttggcatc cacatctctc ctttatctct gattatacgt ggatagccct
    22681 tcattgtcat gaaggattca ttccttcttt ttctcttctt ctgtcaagta cccatcttcc
    22741 attcgataaa cgcgatcact ccattgaatc atacggacat catgagtaac cataatagtc
    22801 gctttttgtt tctcatgagc ttctttaact agtaatttga cgacttcata tgcatgatct
    22861 gtatccaaac tagctgttgg ttcgtctgct aagatcaagc ttggctcatt atataaagcg
    22921 cgagcaattg ccactctctg tctttctcca ccagaaaggt ctttaggata actattttta
    22981 agtgactgga tatctaaaga ttgcagcaag gaatcgattt ttgttgaatc ttcttttttt
    23041 gaagtaactt ggtcaactag ttcaaattgt tcctttaccg ttaaaaaagg aatcaaatta
    23101 gagctttgga gaataaatcc tatttcttta aagcgtaaat ctgctcgttt tttttctgga
    23161 agctcagtta gtgagtgacc gttgatcact atttctccgg aagtcggtgt ttgcaatcct
    23221 cctgaaatgg taaggaaagt acttttacct gaaccagaag gaccaatgat gctgacgaat
    23281 tctccttcct ttacataaaa atcaattgct ttcaaagctg agacctttgt atgaccagaa
    23341 ccaaatgttt tggtaacttt tttcatcgtt aatatttttt tcatttttat taacctccta
    23401 ttgctgtaat tgggtctact ttggttatcg tacgtatcga aaacaatccg cctagcattg
    23461 cgacaatgat caaaatccca ctatatagca accattgtga ccaaaaaaca gcaaaaggca
    23521 tcgcgcttgg taaaatcaga ctagtcaaat aagcaaacaa aagagcaagc agaacgccta
    23581 ccaccccaac aataaaggac tgtgctacta aagatttagc gatgaagaaa tttttgatcc
    23641 cttgtgcttt cattactcca aaaatagcag tcttctgaag tgtcatcacg tacatgaaaa
    23701 taccgaccac ggcagcaacc actaagaaca aaaagtatat catcgcattt aaggtcatat
    23761 tttgggcaga atagccagga atactttcaa tgaatgtccc aatagttaat aactgtagac
    23821 ccttcgatgc tttttctttc gaaattttag ctgaatcctt tattacgatc ccattgatcg
    23881 gctgttcttc ttcagaagca aacggctgtt gtccatactt caaagcagtc cacgtatcta
    23941 gggacgcata gatgacggga gaaactgtgt aataagtttc aggaaagata ccgacaatcg
    24001 tcaaaggatc gtcgtaactg ccaattttga tcgtatctcc aattttatag cctgaatcag
    24061 ccagattttg agagatgatg atttcattct ttgttttaaa ttcatgccct ttcgtgagtt
    24121 ttggtaataa aaatgcttct ttcgttgtgc cgaaaactgt aacattttct ttgttttttc
    24181 ctttgattgc tccgctgtac aatccgattg gtgctttctc tcctccttca atgtatttca
    24241 gatctcctct tgttaattgt gaagctgcaa atacttgatt tgcatcctcc gacaaaacaa
    24301 tctcttgtgc gtcccaatca tcgattgctt ttttaaactc ttctgaaagt ccattcgcta
    24361 gtcctgacaa catgaatacg acatacgcaa tcaagaacat aataccgacg atcaagccat
    24421 atcgtaattt agaatagcga atttctttga tagctagaaa catttgtttt tcctccctat
    24481 gatagattga tagtgacaaa atgtcacttg ttgaatagtg taactctaaa gtgacaattt
    24541 gtcacttgtg ttgttttttt cttatcaata aattgtctaa gacatctttc gataaaacct
    24601 taacatgagt cataaaaaat ttatttaagc cttatttatg ctttccatga taaactaaag
    24661 tgaccaaatc aatgaggtgg gaaaatgatt aaactattag tagtagaaga cgataaagta
    24721 ttatccaata atataaaaga aatactcgct gcaatcggcg agataacaca agtttatgat
    24781 ggtagtgaag gactgttcga gttggaaagt ggagtttatg atcttgcaat cttggatttg
    24841 atgatgccgg aaatgaatgg atatgaagtg ttagcaaaaa tacggaaaga aaaaatacag
    24901 actccagtat tgattttgac tgcaaaagat agtttggaag ataagattga aggatttgaa
    24961 cgaggtgcag atgattatct aacaaaacct ttctatcgag aagaactgat catgcgcgtg
    25021 aaagcattat tgaaacgctc gctaggtctc tttgatgaaa atgttctgaa gtataaggat
    25081 atcagttgtg atttaaaaag caatgaagtc ttgtataaag aacaagtttt gcccatacaa
    25141 ggaaaagagt ttgaattgct cgtttatttt ttacaaaata agggaatcat tttgacaaaa
    25201 gagcagatat ttgaccggat ctggggattt gattctgata cgacgattac agttattgaa
    25261 gtttatatga gcaacttacg aaaacatctg cgaagtactg gattggataa agaaatcaaa
    25321 accttacgta atgtcggtta tatactgcaa agggtgtgat gcaatgaatg gagatattac
    25381 acgaaagcaa cgtagtcgct tttttgcgac aaatgtagca gcatttgctt ttatcttttt
    25441 tcttttggga ttcattactt tacagatatt aaaccaatct gcatacagag aaacagatct
    25501 gtcattagag aaaataaatt ttgattctcg aacagtacaa ttagagatac aaagatatca
    25561 gcaaggcgat ccctttttaa acccgactca aacggaacaa aacagaacaa acatggaaca
    25621 gccattaatg gaaccatcaa atgaccgttt taacactcaa gtgatcttgt ggtctaaaaa
    25681 tggtgagata ttgaataaag cagctattgg tgggcgtttc aaccaaatca aagaattaaa
    25741 aatggatacg aaaaatctga ataccatcca aaatattgaa ttaaatgaag acagtggctc
    25801 atctgccctc tctttccgtt cgattacgaa aaaagcggag acgaatcaag atggcgttgc
    25861 ctacatccaa attttagaaa atacaaatca aatcaagaat tcattagcga cttttcgcac
    25921 gattatgatt ttgtgtatga ttgttttttg gattctctct attggtatca gttattactt
    25981 gtctagtcta agcatgcgcc ctattattct ttcttggaga agacaaaaag aatttgttga
    26041 gaatgcttct catgaattgc gcacaccgtt aacgattatt caaaatagtt tggaacatct
    26101 ttttaccaag cctaatcata ctattattga agaatccgaa agcatcgctc aagcattgtc
    26161 agagacgagg cgcctcactg gattgacttc ggatttgctg acaatcgctc ggaatgattc
    26221 tgatcagcag ctgctttcaa agcaaatgat caatacacaa gaatatatcg aacaacttgt
    26281 taaaccattt caagagatgg ccatcataga tggaaaagag tttattctcc ataacgatgc
    26341 aacattagaa gtaccaattg atgaaaaaaa aatccatcaa gttttggtta ttttgctgga
    26401 taatgcatta aaatatacga atccagaaga taagatcatt ttggattcat ctgttaacca
    26461 taaagaatgg ctgattcacg taaagaatac tggcccttct atcagtgaag aagatcaagc
    26521 aaggattttt gatcgatttt atcgggaaga tcaatctcgg gcgaaagaga ctggcggata
    26581 cgggcttggc ttggcaattg caaaacaggt aatcgaacag catcatggac agatttctgt
    26641 atccaattat cttccacaag gagtcgattt taaagtccaa ttgccgttga agcctaaaaa
    26701 ataatgctta tccctaaaaa agggctgtga caaaaatctt gtcacagccc ttttttgttg
    26761 cgaataaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt ctttaagctg
    26821 accacttctg tcacaacctc tttagcttac gcttacgatt ttttattgcg gtcttcaatg
    26881 tgtacatcac cgcttgtgtc aatatccaat tcttctcggc taacatcttc tgtcactttt
    26941 tcaacatctt catgttcttc tttatgaatc ccaacttctt cacgaataac tgtatgtttg
    27001 cttacatcta cttgctcttc tttgattggg atagtaatcg tgtcatcttc caatttttcg
    27061 tctgttccct gtgaagattg atctgttact ggtttgcgtt cgatgacgat ttcttcacgt
    27121 ttgaccggta cttctaccgt ttcagtatcg ttgaccacat gtttgtggat gtcgacttct
    27181 ccagttgtca catcatgtgt atttacatct aatttttctt cttttagttg aattgtatca
    27241 tcatctagat ttggtttgcg atcgatgtct tcagtcttgc ttgtacccat tgtatcagtc
    27301 tcgccaggta cgtccatcgg atcagttcct ggtgtcatat tcaatggatc cgttgtattt
    27361 tgaaagcctg tcgtgccacc tacgtccatt ggatctgttc cagtgccagt ttctaatcca
    27421 gtccccattg tgcttgctgg gctaacagta tcttgtgtat ccattgtatc ttctgttgtt
    27481 tctggctgac gatagccttt tactgtgatg acaaattttc catcagaaat atctcctcta
    27541 tattgatata aaggatcatt ttctggtgta gccgtctcag aatcataggt atcaaaagaa
    27601 aaagtatctt ttattttttc ccataaagaa cggtcttctt caccatccat ccgattttca
    27661 tctgtttcaa catctatacc agacaatccg tcaaatccta gtctagatgc tgcttcatca
    27721 gtagtataaa taacgatatc atctcgttca tacccttcgt tacgcaaccg ttcaattact
    27781 gataatgctt cttccctcgt actatagctt ccgatgaccg ttaaattttt ctcttccatg
    27841 taaattcctc ctagcaaata
//
LOCUS       DACDAF010000027        27740 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.027, whole genome shotgun sequence.
ACCESSION   DACDAF010000027 DACDAF010000000
VERSION     DACDAF010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.027"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(466..828)
                     /locus_tag="IVZ69_001131"
     CDS             complement(466..828)
                     /locus_tag="IVZ69_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183234.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
     gene            complement(902..1282)
                     /locus_tag="IVZ69_001132"
     CDS             complement(902..1282)
                     /locus_tag="IVZ69_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HAP8183235.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            1364..2539
                     /locus_tag="IVZ69_001133"
     CDS             1364..2539
                     /locus_tag="IVZ69_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP8183236.1"
                     /translation="MIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADMDFLSPG
                     GVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVLTSLAAA
                     VQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDMEKKIEEN
                     NVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHTFTSMLT
                     IDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEINTFGLI
                     GTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLDFTAYIS
                     DDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYALETID"
     gene            complement(2616..3200)
                     /locus_tag="IVZ69_001134"
     CDS             complement(2616..3200)
                     /locus_tag="IVZ69_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP8183237.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            3401..4399
                     /locus_tag="IVZ69_001135"
     CDS             3401..4399
                     /locus_tag="IVZ69_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP8183238.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            4511..5020
                     /locus_tag="IVZ69_001136"
     CDS             4511..5020
                     /locus_tag="IVZ69_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HAP8183239.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(5050..5709)
                     /locus_tag="IVZ69_001137"
     CDS             complement(5050..5709)
                     /locus_tag="IVZ69_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HAP8183240.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(5711..6475)
                     /locus_tag="IVZ69_001138"
     CDS             complement(5711..6475)
                     /locus_tag="IVZ69_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HAP8183241.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(6483..7160)
                     /locus_tag="IVZ69_001139"
     CDS             complement(6483..7160)
                     /locus_tag="IVZ69_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HAP8183242.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(7197..8582)
                     /locus_tag="IVZ69_001140"
     CDS             complement(7197..8582)
                     /locus_tag="IVZ69_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HAP8183243.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(8792..8876)
                     /gene="ffs"
                     /locus_tag="IVZ69_001141"
     ncRNA           complement(8792..8876)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IVZ69_001141"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(8899..9414)
                     /gene="tadA"
                     /locus_tag="IVZ69_001142"
     CDS             complement(8899..9414)
                     /gene="tadA"
                     /locus_tag="IVZ69_001142"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HAP8183244.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            9521..10378
                     /locus_tag="IVZ69_001143"
     CDS             9521..10378
                     /locus_tag="IVZ69_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fis family transcriptional regulator"
                     /protein_id="HAP8183245.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(10459..10794)
                     /locus_tag="IVZ69_001144"
     CDS             complement(10459..10794)
                     /locus_tag="IVZ69_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183246.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(10861..12231)
                     /locus_tag="IVZ69_001145"
     CDS             complement(10861..12231)
                     /locus_tag="IVZ69_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NOL1/NOP2/sun family putative RNA methylase"
                     /protein_id="HAP8183247.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(12309..12845)
                     /locus_tag="IVZ69_001146"
     CDS             complement(12309..12845)
                     /locus_tag="IVZ69_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP8183248.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            13154..14635
                     /locus_tag="IVZ69_001147"
     CDS             13154..14635
                     /locus_tag="IVZ69_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP8183249.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(14738..15445)
                     /locus_tag="IVZ69_001148"
     CDS             complement(14738..15445)
                     /locus_tag="IVZ69_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HAP8183250.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(15524..15862)
                     /locus_tag="IVZ69_001149"
     CDS             complement(15524..15862)
                     /locus_tag="IVZ69_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HAP8183251.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(15973..16935)
                     /locus_tag="IVZ69_001150"
     CDS             complement(15973..16935)
                     /locus_tag="IVZ69_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HAP8183252.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(16950..18281)
                     /locus_tag="IVZ69_001151"
     CDS             complement(16950..18281)
                     /locus_tag="IVZ69_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP8183253.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(18289..18969)
                     /locus_tag="IVZ69_001152"
     CDS             complement(18289..18969)
                     /locus_tag="IVZ69_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HAP8183254.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(19188..19667)
                     /locus_tag="IVZ69_001153"
     CDS             complement(19188..19667)
                     /locus_tag="IVZ69_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HAP8183255.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            complement(19794..21473)
                     /locus_tag="IVZ69_001154"
     CDS             complement(19794..21473)
                     /locus_tag="IVZ69_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP8183256.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            22021..23523
                     /locus_tag="IVZ69_001155"
     CDS             22021..23523
                     /locus_tag="IVZ69_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183257.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            23536..24198
                     /locus_tag="IVZ69_001156"
     CDS             23536..24198
                     /locus_tag="IVZ69_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183258.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(24299..24502)
                     /locus_tag="IVZ69_001157"
     CDS             complement(24299..24502)
                     /locus_tag="IVZ69_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HAP8183259.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(24613..25797)
                     /gene="iadA"
                     /locus_tag="IVZ69_001158"
     CDS             complement(24613..25797)
                     /gene="iadA"
                     /locus_tag="IVZ69_001158"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HAP8183260.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(25954..27693)
                     /gene="yfcC"
                     /locus_tag="IVZ69_001159"
     CDS             complement(25954..27693)
                     /gene="yfcC"
                     /locus_tag="IVZ69_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP8183261.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
BASE COUNT         8246 a         5787 c         4690 g         9017 t
ORIGIN      
        1 aaaagttttt ttcgatttcg tttttcgaaa tctttcagca actcatttat cataacttat
       61 cgtttgttat ttgtcaagaa cttttttgaa gtttttttcg atagaatcaa gcttcgcaag
      121 tggttctttt ttaacgactc agttatctta tcatgtcgtt agtaacatgt caataactat
      181 tttttaaatt ttttagaaat gtgatataac atccacttca gaatcaacgc tgttaaattt
      241 atcatgtatt tcttccttgg tcaactataa attaagcatt actttgtgaa atgatttttc
      301 gatcaattat tattattcgt tatacaaccg ttttcaacat attttgaaaa taaaatgcac
      361 taaaaaacta tctttagcag aacatttcat tgtatttttt ggaccaaaca ataaaaaaag
      421 aagtttgaaa aaaattcaaa cttctttgtt cgcttaatct gtattttaga agaaaggcac
      481 tccctctact tcgtaagttc caagaacaga gcgcatttga cctggttctt cccaaatata
      541 tccttcgcct aattcttctc tttgattctt ttgttcagtt tcaaagacaa acaacggaac
      601 attttcctct ttaatatgtg tatttgtcaa ttccatcaaa ctaatcttgc taacatcgat
      661 atgaactatt tcttttaaga aattaagtat attcgctaaa ccagtctttc cttcagaaag
      721 ttccgctaac gcaaattcca acttgtcatc aattgaatgg accaaaaatt ttttagtacc
      781 atcctccaaa tgcaacataa ttgtaccagc aactcttttg cttgccaaaa tttccacctc
      841 gatcaacttg ttctatggct tacataaaaa ttctagcaca ttttcagaaa aaatacactt
      901 tttatttctt attttctttc cgttctagtt cagataatgc ttcttctatc caaataggta
      961 actgctccgc aatagtggta aatccgatct tacgattttt attcgtgaaa tacctttttc
     1021 tgcgatatgg aacagctgga tttgtttttt ctaacgttct taaagataaa ctgatttttt
     1081 tggaatattc atcaatgtcg atgatctgaa ctgttactgg ctgtccgact tttaacaatg
     1141 aatggatatt tttcgtataa ccggattgta cttctgaaac atgaataagt ccttgcgtct
     1201 cgttatcaag agaaacgaat gcgccataag gctgtatccc tgtcactttt ccttcaatta
     1261 tttgtccaat tttataagtc atctacttcc ctctcttcgc atttatcatt atactgtaaa
     1321 tagctcaaaa aaagaagcga cgaaaatgac tggaggtctt aagatgatcg aatttgataa
     1381 acagatttca agaaaagata cagaaagtgt aaaatgggac gcaattgctg agacatatca
     1441 aatggatgac ttacttcctt tgtgggtagc agatatggac ttcttgtctc ccggtggggt
     1501 agctaaagcg tttagtgaat acatcaaaca tggaatcttt ggttatgcca ctctgtctga
     1561 taaactatat caggctatca ttcattggga acgccaacac catgctgtgg agttgacgaa
     1621 agaaaatatc gtttttacaa gtggtgtgtt aaccagttta gctgcagcag tacaaacttt
     1681 tacaaaacca ggcgattcta ttttgattca tgacccagtt tatcctccat tttcctctat
     1741 tatagaaaca aatcaacgtc acatcgttcg aagctctttg ctagaaaaaa ataatcattt
     1801 catcatggac ttgtctgaca tggagaaaaa aatcgaagaa aacaatgtaa aagcaatgat
     1861 tttatgcaat cctcacaatc ctggagggcg tgtttggagc aaagaagaat tgaaacagtt
     1921 aagcgaattg tgtttaaaac atcaagtgat tctgtttagt gacgagatcc atcaagattt
     1981 aactttattc gatcatacat ttacttccat gctaacgatt gatcctaatt tagatgatct
     2041 actagttgct tttacttccg caaccaagac tttcaatcta gctgcaatca aaaattcaat
     2101 ggtatttatc aaaaatccag agatgaaagc tgattttgaa aaacatttag tgatgaacca
     2161 acagcacgaa atcaacactt ttggactgat tggaacccaa gcggcttatg agacgggtgg
     2221 agaatggtta agccaactga ttccttatct agaaaaaaat gttcaaacag ttaatcagtt
     2281 ttttgaacag tatcttccga aagtgagaat aatgaaccct gaaggaactt acttaatgtg
     2341 gttagatttt accgcctata tttcagacga ccaagaattg gagaacactc ttgttcggaa
     2401 aggaaaagtc gtattaaatc ctggcatcac gtttggtcct tccggtcatg ggcatatgcg
     2461 cttgaatatt gcttgtccag aagaaacttt actggaagga cttaatcgaa tcaagtatgc
     2521 tttagagaca atcgattaaa tcatttattc aaaataaaag gacgagacct tactaggttt
     2581 cgtccttttt cataattact ccgtaccata ccaaactatt ctgaaatttc aattgtttca
     2641 atcactacat catgtacagg tcggtcttgt ggaccacgtt gtacatttgc gatttcatct
     2701 actgtgtcca tcccttctag tacatgtcca aagactgtat gtcggaaatc tagccaagga
     2761 gttccgccac ctttatacgc ttcaatgatt tctgatggga atccagcacc ttctagttgt
     2821 ccaagcatat tagctggcac atttgtgtta tttacaataa agaattggct tccgtttgtg
     2881 tttggacctg aatttgccat agataaagct ccgcgaaggt tgaacagttc acgactgaat
     2941 tcatcttcaa aactttcgcc ataaatactt tcgccaccca ttcctgttcc agttggatcg
     3001 ccgccttgga tcatgaaatc aggaataacg cggtgaaaaa tcacgccatc ataataacct
     3061 tttttggaaa gttcaatgaa attttgaacc gtcttcggtg ctagttcagg gaataattga
     3121 acagtaatgt caccacggtt tgttttgata acagcttttg gtcctttttc actttttaaa
     3181 tctagttgtg ggaatgccat attgtttcct cctaatattt gcatacttca taataataat
     3241 aacataatac ctaacctctc gtaaaaatac tagatttgtt ttcttttatt tttcatcact
     3301 agatacattc tataacttac cgtttcgatt tcgaattcaa acatttttga gaagcattct
     3361 caattaaatt ctgctatagt gtgaaaaggg aggaattttt atggaaatct atgacattac
     3421 aatcatcggt gcaggtcctg tagggatgtt tgccgctttt tacgcaggaa tgcgccaagc
     3481 taaaacaaaa atcattgaca gtctacctca acttggtggt caattagcaa ctttgtatcc
     3541 cgaaaaatat atttacgata ttcctgggta tccagcaata aaagcaagtg aattaatcga
     3601 tcaattagaa aaacaattaa ctacttttaa ccatacattc catttaaaag aagaagttct
     3661 ctcgcttact cgtgaagacg aagttatcga gattactaca aataaaggca tccattattc
     3721 caaagcagtc attttagctt taggaaatgg ttcattccag ccaagaaaat tgaatttaga
     3781 taatgctgaa tcatttgaaa accacggatt ggattatttc gtgaatgatt tgatgaagta
     3841 tgctggaaaa aaagtcgcta ttgctggagg tggtgattct gctatcgatt ggacgttgat
     3901 gttagagcct attgcaagcg aagtttactt gattcatcgt cgcccggaat ttcgtgcgca
     3961 cgaacatagt gtatcacgct tgaaatcttc atctgtcaac ttgcttactc cctatctcat
     4021 cgatggatta tcaggcaata atggggaact gacagatatc cggttaaaaa aagtgaaaag
     4081 tgacgagacg attgatttga tgattgattc tctgatcgtc aattatggat tctcttctaa
     4141 tttagaacat ctttcttctt ggggacttga tagtaccaga aatgccatta ctgtaaaatc
     4201 agatatgtct acttctattc caggcgttta tgcagctggt gacatctgta cctatgaagg
     4261 aaaagtgaaa ctgattgcta ctgggctcgg tgaagcacct actgcagtga acaacgcttt
     4321 acactatatt aatccaaagg aacgaactca gcctggtcac agcacaagct tatacgataa
     4381 aaatcttcgt cctagttgat tttttatatc tctttgcatt tcaagttaaa cccgaaagca
     4441 gtttcttgca tttttttcat gttccgttaa catgaaatag agaaagaaaa aataaagggg
     4501 gagcaataat atggtcgtca aaactgagac tttagaagaa aaggcaagag aactattgaa
     4561 ggaacgtggc gtaactgtag aagatatcgc acaacttgtc atgtttttac aaaaagacta
     4621 tatttctgat ttgactttgg cggattgtac tgaaagtgtc aacagcgtgc taacaaagcg
     4681 tgaagtacat aacgccatta tcactggaat ccaattagat atattagcag aaaagaaaaa
     4741 attgatgagt ccgttgcaac atattatcga agatgacgaa ggcctttacg gtatcgatga
     4801 gatcctagcc ttgtcaatcg tgaatgttta cggtacgatc ggctttacga attatggtta
     4861 tatcgacaag gtgaaacctg gtattttaaa agaactaaac agccacgatg gcgttcatgt
     4921 ccataccttc ttagatgata tcgtcggagc gatcgccgct gctgctgcca gtcgattagc
     4981 acacaaagaa ccagaaaaaa gaagtcgcct tactcaataa ttcaacaaaa aaagaaagaa
     5041 aacgtctatt tagacgagtt ctttcttttt tgtttgtttc aagctatttt ttcctaagaa
     5101 aagaaaaaca gcaaaaaata attctaataa tacaaaaaat aagataaagc tatgcatgaa
     5161 aaattcttct ggaagtacat tgatgattgg atcagtaacg ggatcgaata accagtcatc
     5221 gttgttgaaa aacgtttcat gaaaaaggat aaaaaagcga tcaaatccta tcatcatgaa
     5281 aaaaccgaaa acaactggca gtaacatgcc gatttgaaac ggacgaatca accgccaaag
     5341 ccgatcattc ttttgcaaat atttgataaa caaaatactc gggatcaaag tgatgaaaaa
     5401 cacagcataa tccactaaaa acaaaatttt cacttcataa aagtgatggg ctccgctagc
     5461 agaaactggg aaatctggca agctgaggat ggttttgaag ggattattga gataattcat
     5521 taggtgatca aaatttttca gtaacgtctc ttgatctaaa gaagtataat ccaaaatttg
     5581 caaatgtccg atatcaaata cgtatagtgg tcgaaagttg atcgtcacac caactgccag
     5641 actgatcagt gtcagaaata ggctgaacaa tccagcatat tccatccact gccatctcga
     5701 atttttcata ttagaagctc cattcatcca gtgattgttt cacataggta gctgggatag
     5761 gcaacccagg tacatcttct tcttttgtaa aacctgataa aacgagcaaa gtatctatat
     5821 tattgcgtat cccagcttgg atatctgttt catagttatc tccaaccatg attacttctt
     5881 ctttttgcag ccctaatact tcaacggctt tatccataat gatggcttct ggttttccga
     5941 tgtagatcgg cggcgtttgg gttgctgtct ctacaaaaga gatgactgac cctgctccag
     6001 gaagaaggcc gcgttcagta ggtatattct tatctgggtt cgttccaatg aaagtagcac
     6061 ctttttgaat agcaagtgtt gctttaacta ctttttcata ggtcagataa ttatctaagc
     6121 ctaccactac atagtcagga gcctcttctt cccatgtaaa tccggcagct aaaatcaagt
     6181 caatcaatcc tgcttctccg ataacataga cttttttccc ttttccatct gctttcataa
     6241 aatcgattgt tgccaaagta gctgtgtaga ctgtctctgg agctacatga atgtcaaact
     6301 catctgctag acgattagct actgtttctg gtgacttagt cgtgttattg gtaacaaaca
     6361 agaaaggtaa ttttcttttt tgcaattctt ccacaaatcg tttaccggcc ggtatgggtt
     6421 gtgtcccacg ataaatcgtt ccgtctaaat caattaaata tcctttatag tccattcatc
     6481 cactactctt ccctttttct gatcgtaaat gctgtttttg ttttttctac ttgtttaggt
     6541 tgttcttgtt tttttacttt ttcagaggtt tttgctgact ctgtttttcg atttttaata
     6601 accggttttt tgcgattaga tgcgactggt ccttttttct catcgatata cgcacgatta
     6661 tggttttttt tcttttttcg gcgctgagtt gtcttttctt ttttaccgcc gattctctcg
     6721 atgacaaaat acgcacaacc aaaattgcaa tattcgtaaa gatagtcttc caaggaatcg
     6781 attcgctgat ctggatgcgc ccgtcgatta tccgcttgga aaaatccttt taggcgtagt
     6841 tgttcataac cccaatctcc tacgatataa tcatatcggg ctagtacatc actgtaacgt
     6901 tctccaagct tttctgcatt aaatccttca cgataatcgg acacaagccg ataatgtctt
     6961 tcacctatca aaaaattact gtcatctaac agtgtcacta gctcgccttt gactttttct
     7021 gctttaggct cctcaacgat ttcttccaaa gcagctgtca gttcttcggt gactgttgtt
     7081 tcctgttcag ctgatgattt tttcttagca atttctgttt tatgctcaac gttctgctgt
     7141 tcattttgtt ttgcagacat gcgttcacca cctatctttt ttattatacc ttgtttttat
     7201 ttgattgggt agtgagcttt caagtaatct cctaccacac ttcggataaa ttcagggaac
     7261 aaaaattcat tttttccagc aatctcaatc gttggaaaaa atggaacaaa catcaaatga
     7321 tctacggtag taaaagtata atttttattc agatcgattg gcttgttctt ccaaaagact
     7381 tgatggttaa tagaatcata tgtgattcca ttatagacca tctgcccaaa aatcttaccg
     7441 cgaaatccca ttcccttcat aggatagtta cgtaaaaagt tacgattttt ttctatttct
     7501 aaaactaagc ggatcagatc atttccaccc aatgtgacat ttaacaagtg catcggatgc
     7561 ggcaacgcag tgtgaagctg atcctgattg acccgccctt ttggaatttc agttaaaaac
     7621 agaccactgt ttaatattgc tgcttccgtc tttcctcgtt ctttcaccgc ctcaaaggct
     7681 acttggataa acgaatgctc attgaagata tctagactca gagaaaatgg caaatctgct
     7741 acttcttttt cttttaataa ttcatgccca cgttctagat aactatttat ttcttgttca
     7801 tcttctgtaa aagctgtcat tgtttcggta gggatggctt tggctgaatg cttaaggatt
     7861 tttttctctt catcgatggt taaatggact tcaccgacat actgcccgta ctttccagcg
     7921 gctgctattt ggacatcatt gattacgtga ccttctctga ataaatgatg ggtgtgcgat
     7981 cctaaaataa catcaattgc tggtatttct tttgcaattt ggaaatcatc ctgaatcccg
     8041 agatgactca tcaaaactaa aacatccact tgtgaacgta aatcttcgac taattctggc
     8101 aaaatatcat aaggattccg tatgtcccag ccattcggat tataagtaag cggaaatgga
     8161 gcagtaaatg caattagtcc gattttcgtc tggtgtttcg ttgtaatgat tttatatggt
     8221 ttcgtccatg ccggtggctg gagcgtattt ttatcgaata agttatccag gatgatatca
     8281 aactcagcat gatcgtataa atgattcaac tcttctttgg aatttcctac gccttcattg
     8341 tttcctatcg tcgctgcatc ataaccaact tcattcatca gcaagatatt ttcctgtcca
     8401 ttcgttgctt ctgacaatgg atgccaacga tccacaaaat cacctagatc tactgcaatc
     8461 gttgtcgttt tttctttctt ttcgttttct cgtttacgtt gatccaaaaa ccttctgatc
     8521 cttggccaat tttctaaatg agaatgcaga tcattcgtat gtaaaatcac tattttttcc
     8581 atgtaccctc tcgcctctct ttatctttat cataccatag gcagcttttt cttccattga
     8641 aacaagctct atttcagagt ttttcctgcc ttgaagcaaa ttgtataagt acaatattcg
     8701 ataaatcagt ctggctaaaa aatcaggaac attcattttt acagtactat aaaaataaaa
     8761 aaaacagacc cgaaagtctg ttgtcgtttc attataatca gacacatggc ggaacctgct
     8821 tagtgctgct tccttccaga cctgacacgc ttcacaagcc caccattgtc ctagcctttc
     8881 ggcaaagaat agtatacctt atttttcatt cgttgaccag tcttttttta atttcttttt
     8941 tcgctggcgg agctttcgga aaaagtcagt caaaatcatc ccacattcgt cttctaaaat
     9001 gccaccttct acatatgctt ggtggttaaa ccgctcgtcc tccaaaagat tcatcaaggt
     9061 accggctgtt ccgccttttg gatcatacgc gccgaaataa acttctgcta cacgagacaa
     9121 aatcatcgcg ccgctgcaca taggacaagg ctctaaggta acaaaaagtg cagcatcttc
     9181 caagcgccag cttcccactt tttcacaggc ttccttgatt gcaagcattt ctgcatgtgt
     9241 agtagcatct tgcgtggttt ctctaaggtt atatcctctt ccaatcactt ttccatccaa
     9301 tacaaccact gctccaatcg gaacttcatg aagcatttct gctttctttg cttctgccaa
     9361 tgcaaggcgc atccattttt ctttttctac tgcatcaaga tttgtattta ccaattaccc
     9421 ttccctgcct ttgttttttc ttgttttact ttagcatatg ataaaaaggc tgtaactaac
     9481 ttttttttct atggtaaaat aaatacaaga ggtgaacaag atgaaaatgg ataaattact
     9541 tgctctttac ccacaagcac agaaaaaaaa ctctccagca tcagaagcgg atatcctttc
     9601 ttttgcaatt gatgatgctt ttatctggat caaacaagat tcattatctc aacaagaaac
     9661 cagccttttg aaagcgttat tccctgtaat caacgatcaa aaaaaacacc catggtatca
     9721 ctatcttttt aaagatgctt cttgtgttca agaaaaaagc tttcgtttga tccagcttca
     9781 cgtcgaatca aaaggagaat tcttaaaaaa agaatggcaa gatactattt tggaattatt
     9841 tcgctattct gctgatttct ttttttatac agacacagat gcgctcttag tcgaacaaat
     9901 aaaccgtgat tatcttgatg ctactgaaat caacggtatt tttctatctt tagatgctga
     9961 ttttgatacg acaacgtctg tattcgttgg ttctttccat tcacctggca ccgacctcgt
    10021 ccctttgttt gctgaagaaa gaaaaatttt tttaacagag caaaacaatc tttatactca
    10081 cagccgtact ttttctatgc aagatgtggc tttacattac tatacaaaag atactgtaaa
    10141 agatagtaag ttgatcaaaa gttacataga actgatcaaa caaaatgaaa tggaagtgat
    10201 cattcaagaa ttatggaatg aattaggcaa tgtcagctct gctgcaaaaa cactgtttct
    10261 tcatcgtaat actctaaaat atcgaatcga aaaatttcaa gaacagtctg gtttcaatct
    10321 aaaaaaagcc aacgatttac tgttttgcta tcttttattg cttcatgaac ataattaaag
    10381 atagattaaa ggggttgtga caataatttt gtcacaaccc cttatttcga atgaatagtg
    10441 ttcaaaagct agtttctctt acatcatttt ttcaacaaaa tgcattagcc ggtcttttac
    10501 atcttcggtt gaatctttga ttgaatcacc ataaacagag attttctttt ttcctgattt
    10561 gatttttgct aacattccca tcaaagaatc caagtcacta tctgaaagac catctacgat
    10621 ttctagtaat ttttcatttc catcaaattt gtcatagacg aattttttta ctttcgtccg
    10681 agtagtcata tgatggatct tttccattac ttttcccgat acaacgactg ctgtcgctac
    10741 actggcagcg gctgctacgc ttaatccgat tgttactttt gttgatgttt tcataagtat
    10801 cagctccttt ttatctatct ccatcatagc atagacaaaa aaataaacga actaatccac
    10861 tcagtgaaat ctcaatcctt tagggaaaaa gttctttact gttcctttta cttgtttccc
    10921 aaatccgaca ggtatcttat ctaatactag caaaacccat ccttgattcc catcacgttg
    10981 aaatgtttct cctgctgtgt aagattgcca ttccttttga gtgatcggca agcaaggtat
    11041 attctctatc ttttttgtag caagcgctaa tgcatagcta ggttcaaatc gattcttttt
    11101 gaaatctcct aaatgcaaac ctgtacgtac gacttttaaa ccatcgagag aaggggctaa
    11161 ctcaggaact tcccaaagat ggtcgttgaa cactaaaagt cttccagtag cttcataatg
    11221 aaaatcattt gaaaactccg tccagagttt ttcctgctct tttgtcattt gcactttact
    11281 tttttttcgt gtcttctttt ctttatgcat ctgattttgt ccatgaaaag tcagctttgc
    11341 aacaaaatgt ccttcaccct gatctttatg aggccatata cgtattgttt tttccaaacc
    11401 agctacgctt ccccattcag aacgtcctga actaacggat tgagtcaaag gaatctcctc
    11461 aatcgttact ggataatttt ctacaagcca gctaatgatc tcttcatttt cttctggtgc
    11521 aaacgtacaa gtcgaataaa tcagttgtcc tttatttttt agcattttta ttgctgaaga
    11581 caaaatctct tgctgacgtt tttgacagta tagcggagat tcttctgtcc actcttttat
    11641 tgcatttgga tcttttcgga acattccttc tcctgaacaa ggagcatcaa ccacgatccg
    11701 atcaaaaaag cccgaaaaat gagggacaag ttctgcgggt gcatgatttg tcactattgc
    11761 gttcgaaact ccccatcgtt ctatattttc tgataaaatc ttcgcacgtt tcggaaagat
    11821 ctcattcgtc actaataacc ctttcccctt catttgagca gctaattggg ttgatttacc
    11881 accgggagcc gcacacaaat ccaaaacttt ttcaccgggt tttgctgcag cagctgttcc
    11941 aacgatcatt gcacttggtt cttggctata ttcataccca gcttgatgga ggaaagactt
    12001 tccattgaca gtgccaagaa atccctcatt gctgtaggga gcgggttgta attcttcgct
    12061 atggtaagtt tggaccatgt ccaatcctgc cggttttagt ggattccacc gaaatccttt
    12121 tttcacgctt ccttgttcaa gcgcagaaaa aaaatcggat gcttcttcgc ctaaaagaag
    12181 acgatatttt ttgataaatt gctgtggtaa cgttgtcgct tcctccttca ttccaatgtt
    12241 tcgttagaca ttttacaatc ttttttacga aaaataaagg tggctgatct actttttcat
    12301 gttgctgcct aaggtgactg ttcctttaag atattttcca agtattcatc cgtcacctcg
    12361 tttttatccc aaacagcgtt catcatttca agaaaatctt gagaagaatc atctgagcgc
    12421 aaacttccca atgcattaag ccataccaat tcaagcgact tttcttcttt gatcttcgtg
    12481 tgacctttga catatgagaa aaatggccgc ttaaatagcg aatccatgtc taaatcagat
    12541 tttgcaatga tttcacgaat actttcatgg atagaaaaaa aatctttcaa taagtagaca
    12601 atgcttaaaa catcatcgga actgcattca gctaagtagt tttcaaaata aacagtgatt
    12661 tcttctaata tcttctcttt taacccgctg attgatttga aatgtgtata aatcgggtat
    12721 gtagaacaac cgcagaactc tgctaactct cttgcagtaa ttgacttcat tccatattct
    12781 tccacgtata ccatactttt gaacagcaaa tattctttac tataatttgt tactctcccc
    12841 atcattctta cctccgtctc ttttcatcta cccataaata aataacataa ataattctaa
    12901 aaatattatt gataattatc aaaacatatt tagttatatc cattaaaaat caatttttcc
    12961 gccttaaaaa caagaatatc ttgacaaaat accctaggaa ataaacaata gaataaacaa
    13021 ggtaacaaaa aaattaaata acgttatata aaaaagaagg cgacactctg tgagaataac
    13081 acagactgaa atgactttcc actcacagtt tttgtctaac tatatacaaa aacagaataa
    13141 aaaggaggta tttatgctaa ttgaagcaag aaaaaaagag ttacttgttc tacaaatggt
    13201 cattcaaaaa aataattgtt ctttacaaga attatccaat gacttacata ttccaaaacg
    13261 gacaatcaaa gaactgatcc gaaaaataaa tgtatcactc aagcaatttt tattgattga
    13321 tgaatttatt tattctaatc ataaaggaga gatccaaacc aaagaaaccg atcaaactaa
    13381 aaagttagct gttttttcta agttaaaatt atgctaccta aaagaatcca atcgttttaa
    13441 ctatttgatg ttactaatca attatccaca aactgctgta ccaaaaaaat atttacttga
    13501 acaactttat atatcgccct cctatctcga aaaactgaca aaacagctca atcattcctt
    13561 aaaaaaattc catttacgga tcctatctgt aaaaaattgc tgtactcttg aaggaaatga
    13621 gttatctatc cgtctctatc tttacttttt tctttcagat acatttggag gtaacgattg
    13681 gccattttcc tcacttgaat taaatgcact aaaaatgaac agtacagatg agcaaataga
    13741 aaaaatttca aaacaagaaa aaaatatcta cttgctgtta actttattca tattacgaaa
    13801 caaacaacag gcatattttc caaaaacttc ttctgaaatc actgaattga tggacttatt
    13861 gcagcataca catgattatt cagaatactt tacttctttt tcagtgagtc gcccttgtga
    13921 agagacagaa acagagagag cctactttaa ttattttttc tattgttttt ttccaaatca
    13981 aatctctttt cgacaaaaac aggagattgg ttttttattt tccacaagca aaaaccttat
    14041 ttgtcgacaa gtcggtcaat tgatgactta cttaactcaa cagtttcctc tcaaccattt
    14101 agaaaataaa ataccaattt atttttattt tcttgtgttg gcagttgttt ttttcgaact
    14161 gttgggtgaa tccagcagta gtttttctac actttgcttt ccagaagcca cgtccaatca
    14221 ttctagttct tttatacagg aaaagaaatt aagagaaaaa atcgatacaa ttttttcaaa
    14281 aaatggggaa agaaaccaaa tcagtcaata ccttagtcaa ttgatccaac acttactaca
    14341 aacagaaacg aaagagcagt tactcatcca tttgcagata accaaacagt ttacaggaaa
    14401 ttatcatctt caaagccatt tgcagcagtt atttcgcaaa gatgctgtta aaattaccgc
    14461 atattcagaa catgctgatt tgatcattac agatcagcat gagaaaattt cagatgaaac
    14521 ggagactttc tatctggata caacgcacaa tacagtgtta tttggcaagt taataaaagc
    14581 ggttcatgaa ctgtatatga aaaaaggtta tgagaacaaa acaaagagga tgtgacaaaa
    14641 ttcttgtcac atcctcttat tccaaataaa tggtattcaa tcagctaact ctcggtatta
    14701 gctcagatca aagcgctgat ttcacaactt ctttatttta atctcttcgg ttgccgccga
    14761 acaataagat caagcgcaac agctgcagga atgtcgaaag cgctgctgca acataagtca
    14821 gtgctgctgc aaataatacg tgtcttgcca tcggtacttc ttcttccgtc agtagtccgc
    14881 cttcactcaa aatttggatt gctcgccgag acgcgttaaa ttcgactggt aatgtcacca
    14941 attggaaaag taatgctaaa gaaaaagcga aaatcccgat attgattaac gtagagttcc
    15001 agctaagcaa tacacctacc ataatcaagg ggaacgaaat catcgaacca aagttagctg
    15061 ctggaacaag tgctgcacga atcttcaatg ggacataacc cgaagcatct tgtaccgcat
    15121 gtccgcattc atgagctgct acacctatcg cagcaactga agtagactgt gcagttgctt
    15181 gagacaaact caacatctta ttacctgaat tgtagttatc tgtgagatct ccggcaattt
    15241 gttgaacacc gacattattt atctgttgac tttgtaatat atattgtgct gcttgtgtac
    15301 cagtcacatt gtttttgctt ctcacttgat cgtattttcg gaaagtacta ttgacgtacg
    15361 ctgacgcaat tccggaaata actaatccaa gaatgaccaa aagaaatgtc ggatctaaaa
    15421 aaccatacat tccataacca tacattttcg tttcactcct tttcgtttac tttattttat
    15481 cattagtagt aggaaaagaa tgtgaaaaga ccttgaatat tctttaattc tttttcacaa
    15541 attccgattt cagtttcatc ggtccaaatc cttctacctt gcaatcgata ttatgatcgc
    15601 cttctactaa acggatgttc ttgacttttg ttccttgttt aatggcacct gacgcacctt
    15661 ttactttcaa gtctttaatc actgtcacgc tatcgccctc taacagacgg tttccatttg
    15721 catctaatac cactaatccg tcttctatga cagtttcttg ttcttctttg ttccattcgt
    15781 tcccgcattc tgggcaaatc aacaagcctc gatcttcata tgtgtactct gagccacatt
    15841 ctgggcaatt tggtaatgtc atcttctttc tcctttaaaa tctttagtga gcactattgt
    15901 aacggaaaaa gaagatcttg aaaagataca tttgtgattt ttactacaaa aggcacgttt
    15961 tcgaacgaag tatcattctg tttttctgct cttatacgat tggcatatat cttggatctc
    16021 tttatagatt tcctctactt ctgctaaatc ttttgcattc gcaccacttg ctaatggatg
    16081 gcctcctcca tgatggcgtt tagccaattc attgatgatc ggccccttag aacgtaaacg
    16141 tacgcggtaa taccctgaag gctgctgaac aaaaatcccc caagccagca cttcgtcaat
    16201 cactccagga agtgaaacga tcgaagctgt ctctgaatca tcgattccat atttatcaag
    16261 aatttcttgc ggaaggatta ttcttcctgc accattttca tccacctgga tattttgata
    16321 aagataaccg gaaagtttag cgactttcat cggcatttgt tcaatctctc tgttcaaagc
    16381 acttgcatca aatggataat ttctcaatat cgaagcaatc tctaatgtac gggacgtcgt
    16441 ggagggatac aaaaagcgcc ctgtatctcc gacgattcct gcataaagta accgtgcagc
    16501 cttaacgttc atctttaaag attcaggaaa catcaaagca aattctgcaa tcatctcact
    16561 acagctactt gcttttgtat ttacccacac aagatctcca taagggtcat cattgggatg
    16621 atggtcgatt ttgatcagtt tttctgccaa ctgatatctt tgatcactga ttctgggtga
    16681 attagctgta tcagtcacga tgactagcgc tccttggtag aagacatctt caacttcttg
    16741 catttctgct aaaaagcgaa gcccttcaat cgtttcacct acttgacgta tttctttttc
    16801 tgggaaactt tcccgtaata gttcggctaa tcctacttgt gatcctaatg catcaggatc
    16861 agggcgcaaa tgcctgtgga taatgatttt atcgtatttt tttattgtat ctactatttc
    16921 ttgctgtact gtcatttcac tcctgctttc taagaacgtt ccattacttg acaaacaacg
    16981 attgctttgg aaacgatggt gttttcaata aacacttcga tatccagttt agcggaacgt
    17041 ctgccgattt ccaatacacg tggacgaatg tctaattcgc tttccaattg gatcagccgc
    17101 aaataatgta ggttcacttg ttcaatcaag atatttcgtt tttggttcat caccattgtt
    17161 ttttgtgcga catcagaaat gatttcgcta agtacgccaa aagaaatggt tccaacgcca
    17221 ttgaccattt gtggtgctac tacgaatttg aacttagggt tttccaaacg atttccttca
    17281 cggtcagtat caatcgtatg gatatttcca gatatctgat ccgaaatcgt atctgcaatc
    17341 tgcggttgtc gctggacaag ctgcatcgct ttcattacat cttgccgggt aatcaagcct
    17401 tccaatgtca agtcatcgga aacgaccggc atgacttcta gcccatccca gatcatttga
    17461 tggctaacag aggcaatact cattgttttc tttacactga ttggttcttt cgtcatcacc
    17521 cgatcgatga tctggtttgg cgatttccct aaaacatctt ttgccgtaac aatccccatc
    17581 aaacgatgat ggcggttgac gactggaaaa cgcgaatgct gcgtttcttc tgacaaacgc
    17641 tgataatcag aaatcgtatc tgtctgctgc aaataatgag tcttttcagc tggcatatag
    17701 atatcactga caagcatgat atcttttttg atcaattggt cgcttaacgc tcggttgatc
    17761 atggttgcga ctgtaaatgt atcataagag gtgcgtaaga tcggcatttc aagatcatca
    17821 gctagctttg caatctcagc agtcgtattg aatcctcctg tgatcaatac tgcggcgcca
    17881 tcttccaatg ctaatttttg gacttccgcc cggttgccga cgatcattag tgatcctggc
    17941 gtaatatagc gttccatggc atgtttagtc atcgcgccga tgacgaattt attcaagacc
    18001 ttgtctaatc ctgccgcccc gcctaaaacg tccccttcaa tgatcctgac gacctcgcca
    18061 aatgtcaaac gttcaatatg tttttttaat ttgcgttcga tacggatggt ccctactcgt
    18121 tgaattgttg aaactagtcc gacattttct gcatctttga ttgcacggta cgctgttcct
    18181 tcactgacat tcaattcttt tgcgatgctt cttacagaaa ttcgattgcc aacaggtaaa
    18241 ctttcaatat attctaaaat caaatcatgt tttgtcgcca ttttctgcct acacttccag
    18301 cgtttccgag acgctcatta tttttccttc actatcttcc agtaactcta caaaagattc
    18361 gggatcttgt tcaatgacag ggaaagtatt gtaatggatt ggaactactt tcttggcacg
    18421 aattgtttgc gcagcctttg ctgcatcttc tggccccatc gtatagttat cgccaatcgg
    18481 caagaaagcg acatcaatat cgaattcttc tgcaagcaat cctagatcac tgaaataagc
    18541 agtatcccct gcatgataaa tcgtttttcc ttctgcttga ataataattc cgctaggctc
    18601 gcccatatac tgaacgatac cgtctacttc atagcttgaa ctatgctgtg catgtacgaa
    18661 ttttaccacg ccgaatggaa acgcatgttt tccaccgata ttcataccga atgaatctac
    18721 tcctctgctg ttcgcataat cagcaatctc aacaatactg ataattgtgg cttgattttc
    18781 ttttgcaata ggaatcatat ctcctatgtg gtcactatga ccatgagtaa tcagcaacca
    18841 atctgtcttt acttcttctg cagttaagtc tgtcaatgga tttcctgtaa taaacgggtc
    18901 aatcatcacg cgttggccat tttccatttc aattgttaaa caggaatgtc catgatacgt
    18961 aattttcata ttttacacct cgcgttttct ctgtatcttt tttattaaaa acgatttcat
    19021 cacttgcaca tcaatgaaaa aatatagctg ctaaatatat tttcattgga ttgatagtac
    19081 agtatgtaca aagcaattgt aacagataat acaggatgca ccaagtacca agcagatata
    19141 atctcaagtt tgaggtctct gctctgctta gcttctcttc tcgtccctta actaattaaa
    19201 tcagcgtaaa taggatggac gatcttttct aaatcggcta cttttatccg aaggcttctc
    19261 ccgatttcac cgcttgacac aattacttct tctttttctt ttaaagaact gtctgctaaa
    19321 aaacaataat caggatgtgc gagttttatt ccaatagggg tgtttgctcc gtggggatat
    19381 cctgtatgca ttaatacaaa atccattcca ggaaaaccaa ctttacgatc tttcgtcact
    19441 tgtctcgttt ttttgtaatc taagtgatcg ttcaaaggaa tcaatgcgat gatcacccca
    19501 gttttgtttc ctttcactac gagagtttta catatcaaag ctggatcaat ccctcttttt
    19561 tgtagttctt ctgtgaaaga ttcttctacc acatgactaa aatcaagtgg ttgatagctg
    19621 atcttttgtt cttctaaata acgttcgact tttgtttgac tcatcattga ttcactccct
    19681 ttattctatc gtttattata aagcgaggga tgctgtattc aaaaattatt tgtttttcgc
    19741 aaaaaaagag caagacgagc actctataga gaggttcatc ttactctttt tgtttatttt
    19801 ttatttcgac gttgagtagc ttccataatg actggcaaga tcactgggcg gcgttttgtt
    19861 tgttcaaata agtaacggcc taattgatct cggatgtctt gctttaattt gctccactca
    19921 aaatcattgc tttctaaatg tttctcaacg attgtttcaa tcatattgct gctttctttc
    19981 atcagatcac ggctagcttt tacgtaaacg aatccccgtg aagtaatttg aggttttgaa
    20041 atgattttct tttctcgccg actgatagtg acaaccgcta cgaaaatccc gtcttctgac
    20101 aagatttttc gatcacgtaa aacaatgttt ccgatatcac ctatgcctaa tccatcaatc
    20161 attacatttt ctgcacttgt agttcctgca acactcatac gcttgttctt atattccagc
    20221 acgtctccgc gtccagtaat atagatattt ttgtatggca tccctactgc atgagccaaa
    20281 tctgcatgag cagctaattc acgatactct ccttgaactg gcacaaaata tgttggtttc
    20341 atcaaattga tcattaattg caagtcatta ggattggcat ggccagaaac gcgcatattc
    20401 tcagagatca acttcactgt tccaccagct cgataaatga tatcttccgt tttcgccacg
    20461 atggtttcca tcgcgatgct tggcgtagta gtgatataaa ccaaatctcc ttcttcaatc
    20521 ttgacattac ggtgtgtacc gtttgccatt ttttgcagag acttgatggg ttcacccatt
    20581 cggccagttt ctaaaatgat cagttcttct ggatcatagt ttttcatgtc tttcaacgta
    20641 acaagcagat cttcacttgg taattgaagt ttttctaaac gcatcgctgt gcgaataatt
    20701 cgttcgaaat cttgaccagt caagacaact tttcgttgtg ctttttctgc tgcatccaat
    20761 acttgttgca ctcgttgcaa attacttgct acacaagcga cgatgatacg cccttcccaa
    20821 tatttgatcg tatcaaatac ttcatctgct atttgggctt cagaagctac aggctgagga
    20881 ttttctgcat ttgccgattc acttagtaag gctaagactc cttctttgcc gatttccgcc
    20941 aatcgtgcat aatctgtttg atacattggg atagccgttt ggtcaaattt aaaatctccc
    21001 gtataaacga tactaccttc ttttgttttc agattgatcc ccactgaatc tggtatcgta
    21061 tgagtggtac ggaaaaagct cactactgtt tcaccaaagt ctatttctgt atgctcatct
    21121 accacatgga aatccttaaa tcctttggct gcttcattac gactgacatt caattttgct
    21181 aactcgatcg tcaactctgt cccgaatact ggtacagaaa tttttgacaa caagtaagga
    21241 agtgccccga tcgcatctgc atgtccatgt gttaaaaaga caccagctac acgatcaatg
    21301 ttttcttcta aatacgtaaa atcagggatt acgacgtcga tccccaacaa ctcattttca
    21361 ggatatttta gcccacaatc taaaataaaa atatcctcgc ccacttctgc gacatacatg
    21421 ttttttccat tttcacgaac gccgcctaat gggataattt taatggtact cacaaacttc
    21481 acctcttctt atgacatcca agtttaaaga tgtcgatttt cttctttatc taaatatatg
    21541 agccattcca atgaagcata tgcaaaatca ctatttctca acttatggag aatcagcagg
    21601 aaaattacca gcacatccgc gttctgacag ttggatgggc attttatttt ggatatactt
    21661 cattaacaaa atggatcttt tgcgaaacgc tatagccaga atacttatat aagtattcag
    21721 ctgttcccca ttattataca acaaataaac taaatcgcta gtatcagcaa ttgttagaac
    21781 aactatgcac gtaaaaatcc ctctgtagca tctaggattt cttttgctat tcctctttca
    21841 tttcttcttc gtcggtttga aacatacttt tttcatttta ccacattttt tgcaataact
    21901 atagtgactt tttatatata cagaacctca tgttgatggt gtgcaaacag cataagattt
    21961 aagctagctt taagataggt tgtctattat caaatgcatc tactaggagg gatgcaaaat
    22021 atgaatttta tgaaacgtgc atggaaaagt acaaaagtaa aatggggacg ttcattgtta
    22081 ttgtttgccg tgttcacagc cattcttatt tttgtgctag ctggcctcac gattcgaagc
    22141 gctgcagaag aagcagcgaa tcaagcacaa aaagaagttg gagcaacagt gactttaagt
    22201 gccaatcgag aagcttcatt taaaaaacag gaacaaactt cttcaagcgg ttctaccact
    22261 gaagaacgtc cagatccagg cagtttttct cttacaccag tttccttaac ggacgcggaa
    22321 aaaatagctg aattagataa tgtaaagagt tattcctttg aaagttccgc ctcagctatg
    22381 gcaaaagatg gaataactgc catcactagt tctgattcaa gtgaagacag ttcagaaact
    22441 actgatgcag gcggtgaacc tgctggagga atgggcggga atccgcaaat gactcaagca
    22501 gactttcaaa tcagtggtgt gtcagcaact gcacaaaata gtaatttttc tgatggaaca
    22561 gcaaaaatca cggatggtga aggaatagat gacagcgaca aaggcacaaa caatgtagtc
    22621 attgattcta ctctagcaga aacaaatgac ctggcagtcg gagatacttt cacaatcacg
    22681 agtactgaag atgaagatac cacttatgaa atgacgatca aaggaattta tgaatccagc
    22741 gaaacaagcg gcagtatggg tatgaaattc aacttcatga atccgtcgaa tacactttac
    22801 acttcttaca cttttgcaaa tgaactaaat gggacatctg acgataacac gatagattct
    22861 gctatttaca ctctatctga tccagataaa atggatgagt ttctcaaaga agctgagaag
    22921 ctgatcgaca cagatacatt tagcttacaa tcaaatgatt ccatgtatca gtcaatgttg
    22981 gaacctttaa acaacgtggc aagtttttct aaaaatgttg ttttactagt ggctgtagcc
    23041 ggtattatca tacttactct gatcattatg attaccattc gggagcgtcg gcatgagtta
    23101 ggcgtcttgc tatctttagg agaatccaga agtaaaatca ttctccaatt gtttaccgaa
    23161 gtggctattt gtatgattct tgcattagga gttgcttcgc ttagcggaaa cgtcgtcgcg
    23221 aatgccgtgg gacagcagct acttgaccaa cagacagaaa ccacgacaca aaaccagcaa
    23281 gctcctggcg gtggacaaat gccaggtaac agacaagaac aaggcggtca acgcgatggt
    23341 caacaaggaa ccacgaataa tccatttgct gtttctgatc aagtcagcga attggaaatc
    23401 aatgtcaaac ctgcacaatt gggactatta gccggagtag catttggaat cagtctgttt
    23461 tctgtctttt tagcttctat agggatatta agattaaacc caagaaaaat cctattaaac
    23521 taaaggagga atttgatgtt acggacagaa caattgggat tttggtatca agatccgcaa
    23581 gatgcgcttt ataaagatgt agaactgaat ttcgaagctg gaaaaatgta cgctatttta
    23641 ggagcaagtg gttctggaaa aacgactttt ctttcgctta tttctggact agatgcacca
    23701 aaagaaggaa aggtatacta tcaagatcgt tcactgaaca aaatcgggtt aagaagttat
    23761 cgtaaaaatg atgtctcgat tattttccaa gcttacaact tgcttcctta tttatcggct
    23821 ctagacaacg tcatagcagc aatggaaatc actaagacca agcaagagaa ttatcgacaa
    23881 gttgctttag atcgactggc tcgtgtagga attgatgaaa tattagcaaa aaaacaggtg
    23941 accaaacttt cgggaggtca gcagcagcga gtcgctatcg ttcgtgctat ctgctgtgaa
    24001 catcaactaa tcgtagcgga tgagcctact ggaaatctag atgaaacaac ttcacaagat
    24061 atcgtcaaac ttttccaaga aatcgcccat gaacaaaatc gctgtattat catcgtgact
    24121 catgagattg aagtagcaaa aagctgtgat gaagtctttg aactaaaaaa taaaaaattt
    24181 caaaaaatcg aagtttaaaa aacaggataa tgatcaaata aaaaatccga accatatctg
    24241 tctcgcagat atggttcgga ttttttattt gcttgattca attagtaata agtggttttt
    24301 attttttttc gtcttttcga gaaaacttgt ctttgacttc gtcgcctaaa tttcgagctt
    24361 tttctttgat gtcagcacct agtgattgtg ctttcccttc tgtttctttg ctcttgtcgt
    24421 ctgttgcttt gccgtatgct tcttttcctt caccgactac tttatctttc atatctttag
    24481 aacgtccttt taaatctgcc attgtgcttc ctcctcttag tttgtttatt gatctacctt
    24541 cagggtaaca tcaacaacag atacagacaa acagaacgct cgttttctaa aaaagatagt
    24601 tagagctgtt gattaaaaac ttttttcgaa agtcccccat actttgactt ctttttcttg
    24661 gaccattatt tctcctttag cgataactgt atcaatatca agcgtttctt tatccaagat
    24721 acacagatct gcatcagcac caatttcgat ttttcctttt ttatccaatt tcaatatacg
    24781 tgctggatta ctggttatag ctcgtaaggc gatttccaaa gggatacttt ctttttgcac
    24841 agcttctttg atccctacta gcaatgcctt ggcacttcct actcctaacc ctaggaaatg
    24901 attgttttca tcaaaataag gcaagcttcc ttgtccatct gaggtcatcg tgaaattatc
    24961 taaagaaaca tcttcctcga tcaatcgttt cagtgctttg ctgaagcgaa cttcaccatc
    25021 tgtcttctcc caaaaatcag gatcttcgct agcagtgaag tcaatcgtgc caccacgttt
    25081 ggcaaatgcc acgcaagctt caaataattc tggtgtgcga tttgcatgag taggcaaaaa
    25141 ttgtgtgatc ggaatttctg tttcttctac gattcgtgtc aatagctcta gctttctttt
    25201 tcctccgcct aagtggacat tgatgatccc agcttttccg gataacatgc ctcctacacg
    25261 agcatctgct actgcacgag cgaactcttc aaaacttggc tgagaagaac ggtgatcgga
    25321 tactgcgatt tctccgattc cgataatttt atcaattgtc aaaaagtctt tgatgataga
    25381 atctgttact gtttttaccg gcaatcggta cgaaccttcg tatacataag tggagattcc
    25441 ttctgcttcc agacctttcg ctttgctgat caacgcagtc atatctctac cttctccgtc
    25501 tgttcccaaa caaccgacaa ctgtcgttac accagctgta gtcaattggc tcaatgtgac
    25561 ttctggcgtt cgattttgat aaccgccttc tcctcctcca cctaaaatat ggaaatgaca
    25621 gtcaatgaaa cccggggtta gtacttttcc ctcacctgaa agttcttcta cttccactcc
    25681 ttcgtagccg ccttctagct gttcttctac agccaaaatc ttcccaccgg caatcagtac
    25741 atccattttt cctaagtaat ctggtgcaaa cacttcaatt tgtcgaatga ttttcataca
    25801 tttttcctct ttctttaagt ataactgatg ataggatctt aaaaaataat ccaaacgata
    25861 ggatctttac tcctttgatt ttaccgtaaa atgacggttc ttggagtcct tatctactgt
    25921 ttggattact tttttattta caggtctcca gtactactgc agacctattg caatggcaat
    25981 catgatgaaa atagttccta aaacaaacag gaatccttgc atcttgattt ggaatcttgc
    26041 ccattttgcc cattcgatcc gtgcaacacc tagcacacca atcaagctgg ctgatacggg
    26101 tgtaaaagcg tccataaaac ctgaaccaag ctgataagca agaactgcta cttgtctgga
    26161 tacacctact aaatctgcca gtggagccat gattggcata gtcaaagctg cttgtcctga
    26221 atttgatgta acaaccaagt tgaacaaact ttggaagatg tacatcgccc aagcaccaat
    26281 gacagctgga acaccggtca acgccgtccc gatcccatgc aaaatcgtat tcaaagctga
    26341 aggaacagat gcatcagatc ctcccaagac aagaagaatc cctttggcca tacctactac
    26401 gattgctgta ccagctaaat cagctgcacc agattggaaa gaagaagcga tgtcattgac
    26461 tttcattcca tctaatttga aaagaacagc aatgattcca gcaactaatc ccatcacaaa
    26521 gaattgagaa gcgatttctg gaatgtaata gcctttttga gtcacgcccc aaacgatcca
    26581 gacaaggaca actaacatct ctaataagat caatttatgc ccaagcatga attttttatt
    26641 ttcatcagat gtctttttga tatgagaacg gaaataatca tctgatttgt aagtcaacga
    26701 actttctggt tttttacgga ttttttctgc atatatcatc atataaccag cggctaatgc
    26761 agtaacaact acccacataa tcaatcggaa tgtcgcacca gacaacacgg ggattccagc
    26821 aatcccttga gccaccgcta cgctaaacgg gctcatccaa gaggtcgcat ttccgacttg
    26881 agatgcgaca taagtcacgg ttactgctac gatcgagtca tatcctaacg caatgacaaa
    26941 tggaaccatc accattgaga atggaattac ctcttctgcc atcccgaatg tagcgccacc
    27001 gaatgaaaaa gcaaagaata atagcggtaa agctaaacgc tccagtccct tagttttact
    27061 gataaacgca tagatacctg cgtcgatcgc tccggtacgc ataataatac caaaagcacc
    27121 tccaacaaca aggatcaatg cagcgatccc tacagcagat ccatacttat ctccagatac
    27181 tagtccttca aaaacaaaat ttaagaaacc aaagccgcca aaatcatctg ttccccatat
    27241 tttggctgtt ttatgcaatt ttttagaagt atcatagata ttttcgccgt actgatcgta
    27301 aagcacatca tctgtcaagg agatttcatc tagtttttcc tgcgtaagat ttttttctcc
    27361 gtcagcaatg actttttcca atcctttttc cggaacatcc agtttttcac gttctgctgg
    27421 atgatcttgc agttcttcta attgatcaaa cacatacgac ttatccagct cgtaagcata
    27481 acggaaggaa tcttgacgta aaacagtacg agtacttgtt tcgccatttg catctttgta
    27541 ttcaatatct tgcgtgctga actttcctgc tggaacgaca aaagtcagta tccatgcaaa
    27601 gatgactaca ccaaaaataa tgacatacgt atggggtgtc gataatttag tgaagtcgcg
    27661 tttcggtttt cctgaagaat ttgttttctt caaatttatt tcttcctttc ttttttcagt
    27721 aattttgatg aataaaaaat
//
LOCUS       DACDAF010000028        27588 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.028, whole genome shotgun sequence.
ACCESSION   DACDAF010000028 DACDAF010000000
VERSION     DACDAF010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27588
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.028"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            157..1923
                     /locus_tag="IVZ69_001160"
     CDS             157..1923
                     /locus_tag="IVZ69_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HAP8183262.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETRRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVRDHLDYLTDLGVNGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVYDREDKLYFTRELEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            2025..3284
                     /locus_tag="IVZ69_001161"
     CDS             2025..3284
                     /locus_tag="IVZ69_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP8183263.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            3431..4732
                     /locus_tag="IVZ69_001162"
     CDS             3431..4732
                     /locus_tag="IVZ69_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8183264.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            4735..5586
                     /locus_tag="IVZ69_001163"
     CDS             4735..5586
                     /locus_tag="IVZ69_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8183265.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            5599..6414
                     /locus_tag="IVZ69_001164"
     CDS             5599..6414
                     /locus_tag="IVZ69_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HAP8183266.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            6565..7731
                     /locus_tag="IVZ69_001165"
     CDS             6565..7731
                     /locus_tag="IVZ69_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP8183267.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            7961..8608
                     /locus_tag="IVZ69_001166"
     CDS             7961..8608
                     /locus_tag="IVZ69_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HAP8183268.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            8692..9636
                     /locus_tag="IVZ69_001167"
     CDS             8692..9636
                     /locus_tag="IVZ69_001167"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HAP8183269.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            9771..11222
                     /locus_tag="IVZ69_001168"
     CDS             9771..11222
                     /locus_tag="IVZ69_001168"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HAP8183270.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            11243..12079
                     /locus_tag="IVZ69_001169"
     CDS             11243..12079
                     /locus_tag="IVZ69_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP8183271.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            12079..12738
                     /locus_tag="IVZ69_001170"
     CDS             12079..12738
                     /locus_tag="IVZ69_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP8183272.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSIHQS
                     I"
     gene            12864..13553
                     /locus_tag="IVZ69_001171"
     CDS             12864..13553
                     /locus_tag="IVZ69_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183273.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PKDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            13559..14515
                     /locus_tag="IVZ69_001172"
     CDS             13559..14515
                     /locus_tag="IVZ69_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HAP8183274.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            14559..15071
                     /locus_tag="IVZ69_001173"
     CDS             14559..15071
                     /locus_tag="IVZ69_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8183275.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSGVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(15327..15875)
                     /locus_tag="IVZ69_001174"
     CDS             complement(15327..15875)
                     /locus_tag="IVZ69_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP8183276.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(15964..17145)
                     /locus_tag="IVZ69_001175"
     CDS             complement(15964..17145)
                     /locus_tag="IVZ69_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HAP8183277.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(17381..18889)
                     /locus_tag="IVZ69_001176"
     CDS             complement(17381..18889)
                     /locus_tag="IVZ69_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HAP8183278.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATCLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            19048..19239
                     /locus_tag="IVZ69_001177"
     CDS             19048..19239
                     /locus_tag="IVZ69_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183279.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            19442..20359
                     /locus_tag="IVZ69_001178"
     CDS             19442..20359
                     /locus_tag="IVZ69_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HAP8183280.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            20352..21425
                     /locus_tag="IVZ69_001179"
     CDS             20352..21425
                     /locus_tag="IVZ69_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183281.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            21573..22091
                     /locus_tag="IVZ69_001180"
     CDS             21573..22091
                     /locus_tag="IVZ69_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183282.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            22072..22464
                     /locus_tag="IVZ69_001181"
     CDS             22072..22464
                     /locus_tag="IVZ69_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HAP8183283.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVVFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            22540..23475
                     /locus_tag="IVZ69_001182"
     CDS             22540..23475
                     /locus_tag="IVZ69_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HAP8183284.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            23608..24387
                     /locus_tag="IVZ69_001183"
     CDS             23608..24387
                     /locus_tag="IVZ69_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HAP8183285.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            24380..24697
                     /locus_tag="IVZ69_001184"
     CDS             24380..24697
                     /locus_tag="IVZ69_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HAP8183286.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            24941..26551
                     /locus_tag="IVZ69_001185"
     CDS             24941..26551
                     /locus_tag="IVZ69_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP8183287.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            26708..27556
                     /locus_tag="IVZ69_001186"
     CDS             26708..27556
                     /locus_tag="IVZ69_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP8183288.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
BASE COUNT         8924 a         4883 c         5539 g         8242 t
ORIGIN      
        1 aacttttaaa agttttaagt ctatctattt ggcaagttta aaaaataaaa attcggtatc
       61 aaaaaactgt taccgataac atttttgaaa gcgttgtctt ttgtttctct atcacttata
      121 gtgatgacgt catattaaaa cacaaggagg aaatcaatgg atacagctgc aatttatcat
      181 cgaccggaaa gtgaatatgc atttctatat acgaatacaa gatttcgtat tcggcttcgt
      241 actaggaaaa atgatatcaa aaaagtatat gtgctttgtg gagatccata taccataaca
      301 actgaaaaat ggtatcaaaa acaacgacca atgaaaaaat gtctaagtac caatgttcat
      361 gattattggg aaattgaagt gacgagcgaa acaaggcgct tacagtatgc gttccatgtt
      421 gttggggaag ataacacgga ctgtttttac ggtgatcaag gaatttttcc ttatcgagaa
      481 aatgtgatta ctgaaccaaa tttttatttt cgaatacctt attttcatca aatcgatcga
      541 ttcactattc cagaatgggt aaaagaaaca gtatggtatc aaatttttcc cgaaagattt
      601 gcaaacgggg acaaagcaaa tgaccccgaa cacactttac cttggggaag taaagatcca
      661 gaccgagaag acttcttcgg gggagatttg caaggtgtga gggatcattt ggattacttg
      721 acggaccttg gcgtcaatgg catctatttt tgtcccatat ttaaagccac atccaatcat
      781 aaatacgata cgattgatta ttatgaggtg gatcccgctt ttggcgataa aaaactttta
      841 aaaaacttga ttgatgaagc acataaaaga gggatacgta tcatgttcga tgctgtattc
      901 aatcatatgg gtgtccattc accacagtgg caagacgttc tcaaaaacgg agaaaaatcg
      961 atctataaag actggttcca catccgtttt ttcccagtag attcttatca gatgactgac
     1021 ttaccagaaa ctgctgaaaa tatcccatat gatacttttg cttttactcc attcatgccg
     1081 aaactaaata cagcaaatcc agaagtgcaa aaatatttgc tggatatcgc aacttattgg
     1141 ataaaagaat tcgatattga tggatggcgt cttgatgttg ctaatgaagt cgatcatcat
     1201 ttttggaaaa aattcagaga agcagttaca gaaatcaaac cagacatcta tatccttgga
     1261 gagatttggc attcctctca agcttggctg caaggggatg aattccatgc agtgatgaat
     1321 tatgcattca cagattcgat taaagattat tttgcaaaaa agaaaatcac agcttcacaa
     1381 atggtcagtg gaatgaatca tcagcaaatg ctttacagag atcaggtgaa cgaaggaaca
     1441 ttcaacttat tagattctca tgatactgcc aggatcttga ccctttgcca aggtaacaaa
     1501 gaattgatga agtctgtgat ggcctttatg tttcttcaaa aagggtctcc ttgtatctat
     1561 tacgggacag aaatagggat gactggtgaa gatgacccgg attgccgcaa atgtatgata
     1621 tgggagaagg aggaacaaga tctagagcta ttcggtttta taaaagaact tgtttctcta
     1681 aggaaacagt tgtctaagat tatttctgaa ggttctactc agtggctaat agtatatgat
     1741 cgtgaagata agctctattt cacacgggaa ctagagggac agatcatcta tgtttacttt
     1801 aatcagtcaa aagaaccttg ggtagtagaa caggaaaatg aggtgattct tagtcaaaat
     1861 tgtcagttgt tagaagacgg gaaagcagag atacgacaat acggattttt gatcatgtgt
     1921 tgaaaactgt taccggtaac aacaagaaag cgtttgcaaa tgaagatttg tgcccattat
     1981 aataagggtg taacagcacg ttgaatacac aggaggaaat gaagatgaaa aaaagaagtg
     2041 tgaaacagtt gggtttaggg ttaatctctt taggaatctt aggcggatta gcggcttgtg
     2101 gcaatggtaa ctcttcagca gaaggggaag ccgatgaagg aaaaacgtta acagtttccg
     2161 ttgattctgg atataaagat tatataaacg aaataaaaaa cactttcgaa aaagaaaacg
     2221 atgtgaaaat caagctagta gaaaaggaca tgttcgatca gttggaatca ttagcgttag
     2281 atgggcctgc tggaaaggga cctgacgtta tgatggcagc atatgaccgg atcggtgcgt
     2341 taggacagca aggacatctg gcggaagtaa aactgggaaa tgaagcagct tacgatgaaa
     2401 cagacaaagc ccaagtgact tatgatggaa aaatctacgg agaacctgca gtaatcgaga
     2461 cccttgtttt gtactataac aaagatttag tcgatacagc accatcaacg tttaaagatt
     2521 tggagaatct atccaaagac agtcgttttg cttttgagtc agaagcagga aaaaatacag
     2581 gatttttagc taaatggact gacttttatt attcctatgg tttaattgca ggttacggtg
     2641 gctatgtatt tggtgatgat ggcacaaatc cttcagatat cggtttgaat aatgcaggtg
     2701 ctgtagaagg aatctcttat gcaacagatt ggttcaaaaa tgtttggcca aagggaatgc
     2761 aagacataaa aagtgcagga gacttcgcca gccagcaatt catgtccaat aaaactgcag
     2821 caatcattga cggtccatgg caagcgcaaa catacaaaga aaacaatatc aattatggtg
     2881 tagccaaaat tcctactcta aataatggac agccttatca accgtttggc ggaggaaaag
     2941 gatgggtagt cagcaattat gctaaaaaca aagacctctc tcaaaaatgg cttgattatg
     3001 taacgaatca ggaaaatcaa gaaaaattct ttgaaatggt aaatgaaatc cctgcaaacc
     3061 aacaagctag ggaaacagca aaggctaaaa acgatgaatt aacaacagct gtgattgaac
     3121 aatatgaaac agctcaagcg atgccaaaca tcccagaaat gggcgaagtt tggacaggtg
     3181 cagaaaactt gatgttcgat gcagcatcag gttcaaaaac accaaaagaa tccgcagatg
     3241 aagcagtaaa aacaatcagt gaagccatag aacaaaaata ctgattaaaa tgataaccgt
     3301 ccatttttat aaaaaatgga acaggtgctt cagataaaag tggcaagagc gagatggaaa
     3361 attatcttgc tcttgttgcc attatcttaa aagcagtttg cggtttagca agtttagagg
     3421 gggcattcag atgcagcaag ataaaacaag caatatcaac gaaaaaaaaa tcacgctttg
     3481 ttcacttatt ccagggatgg ggcagtttgt aaatggccaa gcttttaaag gtatcgtttt
     3541 tttcgccata ttcgtcctat tcattggtca gatgcttctg ggcggatttc atgcattggt
     3601 aggattggtt actttgggaa gtataccaat ggaagatcat tcattattta ttttgattga
     3661 aggcactttg caattcatca ttacaatcat tttcttgatt ttttacggtt tgaatctttt
     3721 agacgcttat cgagtagcga agatgcgtca agagggcaaa aaaatcaatc ggacgatgaa
     3781 ggaagtcata cataatatag gtgatgaagg ttttccttat ctattgacac ttcccgctta
     3841 tcttctcatg atttttacga tcattttccc agtcctagtt acattgttca ctgcatttac
     3901 taattatgac ttcaatcata ttccaccagc cagtttaatt gattgggtag gggctaaaaa
     3961 cttttttagt atcttctttt taagctcata tcgtaatact ttttttgcag tcttttcgtg
     4021 gaccgtgatt tggactttat gtgcaacaac tttgcaaatc acccttggta ttctcacagc
     4081 ggttgttgct caccagaaat ttattaaatt caaacgtatt ttcggtatca ttttcttatt
     4141 accatgggcg gtcccagctt ttattactat catgagtttt tcgaatatat tcaacgatag
     4201 cgtaggtgcc atcaatactc aagtgattcc tttcataaac cagcttcctt ttgtagatat
     4261 cagtgcaatc tcttggaaaa cggacccgaa ctggacgaaa gtagcaatta tcttagtgca
     4321 gggctggtta ggatttccct atatctatgt gatggttaca ggaatcttac aatcgatttc
     4381 agaagactta tatgaagcag caaaaatcga cggagcaaat gcatggcagc gcttttcaaa
     4441 catcacgctt cctgctgtct tcctagtggc agcgccaaca tttattacac agtatacggg
     4501 gaatttcaat aatttctcca tgatctatct gtttaacaat ggtggtcccg gaagcgtagg
     4561 cggaggagct ggttctactg atattcttat ttcctggatc tataaactta cgactggaac
     4621 ttctccgcag tattctatgg cttcagcaat cacgttgatt atctccgtca tcgttatctg
     4681 tgtgtcattg ctggtattta aaaagacaaa tgcgttcaat atgggggatt aacaatgaaa
     4741 aaatttcatt cgagtgctcg attccaaaaa cgactttctc acttttttac ttactttttt
     4801 cttttaatac tgtcagtcat tatcatctat ccgcttttga tcacagcaag tactgccttc
     4861 aagtcaggaa atattgcagc ttttagttta gatctttcaa gtgactggac tttaggaaac
     4921 tttactcggc tattcagtga aacactttac gggacttggt ataaaaatac attgatcatt
     4981 tctgtcctaa caatgatcgt acaagtgact gtagtaactt tggcgggcta tacttatagt
     5041 cgctatcgtt ttatcggccg caaatcaagt ttgatgttct ttttagtgat tcagatggta
     5101 ccgactatgg cagcattgac tgccttttat gtcatggctt tcttattaga agcgctcgat
     5161 aagtactggt tcttgacaat gatctatata ggcggtggaa ttccaatgaa tacttggctg
     5221 atgaaaggat actttgacac tgtaccaata gatttagatg aatctgctaa acttgatggg
     5281 gcagggcatt tcaggatttt tttccagatt gtattaccgc ttgtcaaacc gatgctcgcc
     5341 gttcaagcat tatgggcttt tatgggacct tttggggatt tcatgttagc taagttcctg
     5401 cttcgaacac ctgaaaatca gactgttgct gtcggcttac aaacatttat ttctgatgtg
     5461 acaaaccaaa gagtctctct ttttgctgct ggggcaattt tgattgcact accgatttgt
     5521 ctattattct tctttttaca aaagaacttt gttaccggcc tgacatctgg cggaacaaaa
     5581 ggataggagc agagtatcat gcaaacattt ccgttaaact atttttccgc attacgtacg
     5641 ccaactcaag tgtttgcggg acgcaaacta ttatcatggc ctaaattttt cttgatattt
     5701 gtatttttag tttccttgat ggtcatgcct gtgactcttt tttatgccaa tcagatccaa
     5761 gcgattccat tagaacaatt tctatccgtt cattcgctga tcgatgaaca aggaacccaa
     5821 aaattttctg aacttgaatt atctgaaact gggttacaag catcgcaaca aacgatagct
     5881 gtgacccctg aaattttggt aggtgtgtct ttatctgaga aacaacaatc cgatcatgga
     5941 acttttattg attttgagaa ggaacaatgg gtgatccaac aaaaggataa atctggtata
     6001 cgccgctata cgatgaatta tagcccatct ttccaaccag attctgtacg tacgcccgaa
     6061 gatttccaac gatttttaga aagagaattt tatgccagta atcgtccaac aatcatttta
     6121 tcttatagtt taagtcttgg tcttgtccta tttgtcatga cgagtctcat tttattcggg
     6181 gcttcctttt tcttgtggat gacaagaaaa agccaacttt catccattca tacattcaaa
     6241 gagagtgcaa atttgatgct gaatgttatg ggaataggtt ccatggcagc agcagttgta
     6301 gggtttatcc actttgactt tatcttgatg ctaagtgtcc aaacaacgat aactgtcttg
     6361 ctgcttttat gggtttttgt caaaacaaga ttcaaagata agcgtgtcga atgacaagtt
     6421 taagcgattt atgcgacaat gaatgtgaaa aaaatgaaaa ataaagtagt ttttgaaaaa
     6481 tttctgaaaa aattaaactt cttagttgat tcttttcttt tttagtatta acgtaatagg
     6541 gtagtttttt taaggaggaa aatcatgtta gagaaaactt tatacaatca attattttca
     6601 cgttctttct cgctccctgt cgaagtaaat tattgggacg gtacaacgaa acaatacgga
     6661 gatacggaca ctcctcccca aatcaaaatc aatatccatg aagaaatccc aatgaaagag
     6721 attacaagta acgcttcttt ggcactagga gaagcctata tggatcatcg aatcgagatc
     6781 gagggaagta tccaagcatt gatcaacgat gcttatcagc aagcaaacag ctttttacga
     6841 ggaaaagatt atctaaaatg gctgccaaag aaagaaaaac atacgaaaca aaaaaacaaa
     6901 gaagatatcc atgcgcatta tgacttaggt aacgactttt ataaactttg gctagatcca
     6961 actttgactt attcttgtgc ttatttcaat acacctgaag atacgttgga acaagcacaa
     7021 atcaataaag tccatcatat cttagacaaa ctctttatca aagaaggcga aacgttgctt
     7081 gatatcggtt gtggctgggg aacattgatg ttcactgcta ccaaagagta taatgtcaag
     7141 gcaactggga tcacactaag tgaagaacaa tacgatttga ttaccaaaag aataaaagaa
     7201 gaacatttag aagataaatg ccgtgtatta ttaatggatt accgcgaact aaaaggcgaa
     7261 acgtttgatc atatcacaag tgtaggtatg ttcgaacatg taggttctga aaatcttgaa
     7321 ggttatttca aagtggtaaa agatttattg aaaccaaaag gaacagcttt gatccatgga
     7381 atcagccgac aacaaggcgg tgcgacaaat gcttggatca ataaatatat tttccctggc
     7441 ggttatgtcc ctggtgttac tgaattagtt gataatatta caaaaaacga tttgcaactg
     7501 attgatttgg aaagcttacg tcgtgactac caattgacat tagaacattg gacaaagaat
     7561 tttcatcaag tccaagatca agtcacgaaa gaaatgggtg attccttcta tcgaatgtgg
     7621 gatctatatt tacaagcttg tgcagcttca tttgaatcaa gtaatatcga tgtgattcaa
     7681 tatttgcttg ttcaacctgg aaacaatgac atcccaatgc atcgtgcata attgaggcaa
     7741 aagtactgtt taaagactat ttaaaaagaa gctaagtttt atgatgctcc agaagtgaac
     7801 ttttttgtct aacttctagg attgtctcta aagcttagtt tctttttctt tatattttca
     7861 taataaaagt ttggttcttt aatttttaaa catgacagaa aattttttct tcgttatact
     7921 tgtaatagaa tactatttta taacaaaggg gatcgaatca atgaaaaaaa ctgttattta
     7981 tactagttta tttgcagctt tgtttttagc tgcttgtcaa tcaaatacca atcaaggcac
     8041 atctgggaat acgtcttcca gtagcgaaca gcgctcttca caggtatcgg actcctcaac
     8101 aaaagcaagc acatcttcgt ctagccagac aaaaagttct agtgaagcaa gtactcagtc
     8161 agatatcaaa gtgtctgcag ctcgtgcgat cgaattgttc caagataaat acccagatac
     8221 tgcaattact agtttggaat tagatagtga ttggggatct tacttctaca agatagaagg
     8281 tgtcgatgat caaaaagaat acgaagcaag aattgatgct caaaatgaaa aaatggagac
     8341 agagaatcca gaaactctag atcgagatga acaaaatggt caaaagaaaa aagaagatgg
     8401 tctggatgtt gataaattga tcacgattga ggaagcagca aaaatcgccg tcgacaaagt
     8461 aggaagcggt acggcaacag attgggattt ggataaagat ttaggtacta cttattggga
     8521 agtcaaagta aaagacggca atcaaagtac atcagtcaag atcaatagcc aaacaggcga
     8581 agtactgtca actgaacaag atgattaaga atttcttcgg aaaacaagag ttgatttttc
     8641 ttttagtcat gatacactag acaaaataac ttgtttgaag gagcgattta cttgagttta
     8701 gaaacgacct ttgccaatca tatctttgcc aatcctttga tgaatgcatc tggtgtccac
     8761 tgcatgacta cccaggaatt agatgaactg gctcattcag aagcaggagc atttatcact
     8821 aagagctgta cgatcaatga acgaaaagga aatcccgaac cacgctattt tgatgttcct
     8881 ttagggagta tcaattctat gggacttcca aacttaggtt tttcttatta tctagagtat
     8941 gctcttgcgt atgaaaaagt gcaggaaaac caaaatcaac cgttattttt ttccattgcc
     9001 gggatgagtg tccaggaaaa cttggaaatg cttgagaaaa tagaaaaaag tgggtttaat
     9061 gggatcactg aattaaattt atcttgtccc aatgtgcctg gaaaaccaca actagcttac
     9121 gattttgagg ccacttatga aacactgaaa gaagtattca gcatcttttc taagccgcta
     9181 ggaatcaaat tgcctcctta ttttgatttt gctcattttg atcagatggc tgatatcttg
     9241 aatcagtttc cattgaccta tgtcaatgct atcaacagtg tgggcaatgg tttgtatatc
     9301 gatacagaac aagaagcagt agtcatcaaa ccaaaagaag ggttcggcgg cattggcgga
     9361 gagtatatca agccgactgc tttggcgaat gttcgcgctt tttatacacg tttgaaacca
     9421 gaaatccaaa tcattggtac aggtgggatt cggacaggac aagatgcatt tgaacatctg
     9481 ctatgtggcg caagcatgtt acagattggt acagagcttc ataaagaagg gccggaaatt
     9541 ttttctagaa tcataaaaga attaacgcag attatgtcag aaaaaggata tacgtcaatt
     9601 gacgaattta aaggcaaatt acgcaccatt tcatagcaaa gagacgaagg tcatgattga
     9661 tcttcgtctt tttttataaa aaacactcgt ctgttcattc ctgtgcaagc gtactcattg
     9721 tatgttagac gaacttgtgg gaaaataaca gaggcaaaaa ggaggataat atgaatgatg
     9781 caacagaatt agcaaaagag cttaaagaaa aagaatttag ttttcaagaa ctagttacgg
     9841 atatacagaa aaaaataaag aagcaaaatc atgaattgaa tgcgtttgtc gcgcttgaac
     9901 cattcgagag taattcccac gagctattga ttccccagtc agaaaaaggg ccattggctg
     9961 gtatcccatt tcctttaaaa atgctcggtc aagaaaaaaa gggatggcta gctacttcag
    10021 gatctcgttt atttgaaaca caccgagctt ctcatacatc taattatgtg cggcaagcag
    10081 aagcgatagg tctagttcct tttggacaaa ccaatgcgcc agagtttggt ttcaaaaata
    10141 ttacagaccc agtcatctat ggcccagcaa gaaacccttg gaaccttgaa tgtacaccgg
    10201 gcggatcaag tggaggagct gctgctgcag tttcatcagg aatcgttcct ttagctggtg
    10261 ctagtgatgg cggtggttct attagaatac ccgcttcgtt ttgcggattg attgggctga
    10321 aaccttcgcg agggacgatg ccagttggtc catatgcttg gagaggatgg caaggagctg
    10381 ctattgattt cggcttgaca gtttctatga gagacacgga ggctttattt tatgggatga
    10441 gaagtatcca ttccggtgcg ccatatcaag tatcgccagt tgagtggcaa acacatccaa
    10501 gaaaaaaacg gttgaagata gctttttgtg ttgattcacc gatccactca cagattagtg
    10561 aagaggcagt acttgctgta aaaaaagctg tagatttcct tggaaaagaa gggcatgatt
    10621 tgacagagat tccttaccca ctagatggtc gtaaactgat cacgtcttat tatcagatga
    10681 atggcgcaga aacagcagca atgatccgct cgattgaaac aggcatccag cgagctgtca
    10741 gaaaagaaga acttgaaccc atttcttgga ctttgttcca atatggtcag aagctctctg
    10801 ccgctactta catcgattct ctgcatgtat gggatgaagc agcaattgtc atggaaaacc
    10861 tacatcaaga atacgatcta ttcctttcac caacgactgc atttaccgcc cctaaaatca
    10921 gcgaagattt gcaaagtgat gcgataagag cacagatgga acacatcagt gattgttctg
    10981 aagtagaagg tttagacgtt gtttcttcca tgtttgagga gagcttgaag atcacacctt
    11041 atacacagtt ggctaatctg actggacaac cagcaatcag cttgcctact catttgacaa
    11101 aagaaaacat gcctctagga atccaattta tggctgccag aggaagagaa gatttgctat
    11161 ttcaaatcgg ctatctattt gaagcaaatc atcagttcca tttaccaaat ccatggaaat
    11221 agcagaaaca aggagaagaa gaatgaagaa aaaaagattg tttgctctaa taactagtgc
    11281 cttttttatt ttaagcgctt gcggtacagc tgccgctaat caggaagata acagctggag
    11341 taatgtagaa aaaaagaaag aattagtagt agcgacttct ggcacactgt ttcccgcatc
    11401 ttattataat gatcaaaatg aattagttgg ttatgatgta gatttggcaa aagaggtggc
    11461 taaacggtta aatgtcaaaa tctcctttaa agaatacaac gtggatggac aaatcacttc
    11521 tgtttcaaaa agagaatcag attttgctgc gaacgatttt ggtatcacaa aagaaagaga
    11581 aaaaaaattc tccctttcag agactttcaa atattcattt gacagtatga tcgtacgaaa
    11641 aaaagatgat tcaggaatcc actcacttga agatcttaaa gggaaaaaag cagctggcga
    11701 acccaatact agctatatgc gtttagcgga aaaacacgga gctaaattag tcacatatga
    11761 caatgccacg aatgatcagt atttaagcga tgtagcaaat ggtcgaacag atgttattct
    11821 aaatgattat tatctgcaga aaatggccgt atctgcttta ccagatatcc ctgtaaaaat
    11881 actggagaac gtttatttca atgaaaacga aagtggtttt ttattgaaag aaggaaatga
    11941 tgctctgaaa aagaaaatcg atggcgtatt aaaagagatg aaagaagatg ggacgacaaa
    12001 gaaaatatct gaaaaatatt ttcaaactga tgtttcagtc aaaccgaaag aaacgatggc
    12061 tgagtcggtg agtgagtgat gtactttccc ctaattgatt tttccctcat gtggacttca
    12121 cttcctttcg tactgcaagg cttggtatac acattaggga ttggcttcgt gtcgtttctt
    12181 ttaggaaatt tggtagggtt gcttttgaca gttttaggtc ttttggattg gctgcctctg
    12241 aatgtattta ttcgttttta tttatcgttc tttagaggca ttcccgcact agtcctgctg
    12301 tttctgttat atttcgggtt accttatcaa ttaagtgcct taacggcttc agtcatctgc
    12361 tttacgatta ccagcagtgc atttattggt gaaatctatc gaggatcact agcaggcgtt
    12421 tcttcaggtc agtgggacgc tggtttagct tctggttttt ctttctttgg ggtattgaaa
    12481 tatatcgttt tgccgcaagc ttttcgaatc tcagtaccgg cactcagtaa cgtagctatg
    12541 gatctagtga aaggtacttc gttagcagca acaatcacag tgccagaaat atttcaaaaa
    12601 gcaaagatca taggcggtcg gacattcgat tatttttctc tctatatttt agttgcactg
    12661 atttattggg tcatttgtat cgggatcgaa aaagtgcaac agtatttaga aaaacgttct
    12721 atccatcagt caatctgaaa aatagaaatg gtgctagcgt ggctggcacc atttctattt
    12781 tttgtttctt gtatattctg cctagtattt taaaaccatt tcatgtaaaa tgtaaatcga
    12841 aaatatgttc ggaggtagaa aacatgaaga ccccgctaac catcgaaata gaatcctcgt
    12901 tataccaata ttgcatcgag caaggcggct tggttgtaga agaagtcacg atgcctgatg
    12961 accaaggaat tgtagatacg cttagctgct tgacaaaatt tgatggaagc cgagaatggc
    13021 gatgctatga gctgaaagtg acaaaagcag attttcgctc tacagccaaa ctgtcatttg
    13081 ttggacatta taattatttt gttttaccaa gtaaactata tgaagaagta aaaactgaaa
    13141 tccctacagg aataggtgtt ttagtgtatc gtccgtacac ggttgaagag gagatgcctg
    13201 cctctggtac atttctgatt gcgaaaaaag cagcaaagaa agagcttgct gtaccggaag
    13261 aagctttgac aaaccgcttc atggcttctt tattcaggga agtaagaaaa gcaaagcaaa
    13321 tggagcgagg cgtaaaatat tttccaaaag atcaattgta caaagaattg aaaagacgtt
    13381 cagaaaatca agatccattt tctaacgaac gatattatga acggttttta gaggaaatag
    13441 ctagtcaggc aatcaatgag ttgcaagaag aagttatcgc gcttcagcat gattatgaat
    13501 atttgaggca acaacagcag atccgtcggt tgcctacaga gccattggag tgaaaaatat
    13561 gtactatcct tatttaagag gaaaacaatt tgacctatta gcattaaaag aagcactgtc
    13621 gcgaggattg ctctccaata aaatccaacc agtgatcgaa ccagtacgtg attccgctac
    13681 gcttaaaaat gtgatcgaat tatttcaaaa aaagcaccat ccaatcgctg tgatccaaaa
    13741 tccccaagta ggacaattca aattattcga tcagcatgtg cacagttgga cagtcaaaga
    13801 aaatagctct gtcgtccctg cacagatctt aacgccagaa aatctcagtg aagtactgga
    13861 ttcacctcca gcgtttcttg ttttcgatgg acagcactac ccaaaagata cagaggtgtg
    13921 gaaacagttg gcaggagttg attcgaaatt tttgatacca gatactagtc gctttcgcat
    13981 ctggctgccc gaaaacaaaa ttgtgatccg tgactctttt caaacgagaa agcatgttga
    14041 aagttatgca gataaaacag atgacttttt tagtgatgac tatctttttt tccacgcaga
    14101 cggatatatt ggattttctg atttcacgat cgaaggtagc cgttatttcg ataaagggtt
    14161 ccctagccga gcgcttgcta tccatctaac gtatattgat gcttacggca atatacgcgt
    14221 gaaacatttt gtctctgaca gtaacgactc tgctaaagac caagcattga agtttcttga
    14281 agcaggagat aaaatgaaaa aatggatcat gcgtcaccat catcaactct tgattacttc
    14341 aggaatgatt gaattattgg ctctttacca gcaacaaaaa ttccctggac tgggagtgtt
    14401 gaaaaagtgg tcacttatgc atcatttgga acttattagt cacctgctag atcatccaaa
    14461 agattggctt aaatattatt caaaagttca ggaactatat gaagtgatcc aatgattaga
    14521 taatgtaaat gaaaaaggaa tagaaaagag gaaactggat gtatattcgg caaacaagga
    14581 aagaagaagt agaagaagtg gtagaaatca ttaatgccgc agcggatttc attgcttcgc
    14641 aaggctctcc tcaatggcaa aacgggcaga aaccaacaaa agaaacgatt ttgaacgata
    14701 ttgaaagaaa agaaagctat gtattaatag tggaagatca aattgctgga acagctgcat
    14761 tagtctcagg cgtggatccc gtttacacaa aaatagatgg tagttggaaa gaatcaactg
    14821 gtccttattt atcgattcat cgtgtcgctt tagcagaaag tactcgagga aaaaaactag
    14881 caaaaccgtt cttagaacat ttgttgacga ttgcagccag caaaaatatc caagatatcc
    14941 gtatcgatac ttatccagct aatgaaccga tggaaaagac catctattct gctggattca
    15001 cttatcaagg gatgattgaa tttccttttg aacacggcga aagaaaagca tatcaaataa
    15061 tcatcaattg actataaaat catctgagca aagataaaga cattaacact actgaaaaaa
    15121 acaatcatat gatagccaag aggttgtaac agaagtggcc agcttcaaaa aacaagaaag
    15181 aatttccgaa aatgcttctc aaatttttgt ggaattttag cgtattttac gaaatagctg
    15241 ctttctgaaa ctcccttcat cgagaggtcg tgacatagct tttgtcacga tctctcggct
    15301 tatcctacga gtattattcg atacatttat atcaataatc ctttttttat tttatctgca
    15361 gcttcttgga acgctccatc gtttgacacg actaaaagtg aggggatagc tttcaaacgt
    15421 ttcaactgtg ctaaatcttc tacataaacc gccagtctgg ctgaaatctg ttcagatgaa
    15481 tctccacgtt ttttcaggcg cgattgcaat gtttctttag agatcgtaat aaagatagga
    15541 cggactaccg tcccgaaata ctcatataaa tgccaaaaac catttgctgt caaaacggcg
    15601 taacaatttc ctactgtcag tttcttttta atttctgctt tactggaacc atatttatgt
    15661 tgagcatatt ggtcccactc tgcaaactca tttcccttga tcatctgatt gaatgtattg
    15721 tcagaaacaa aataataatc ctcttgatct ttttccccag gtcttggtga tcgattcgtg
    15781 taagtaatga tcttttgttc cggctgaaaa atagcttctg cgagtgaagt ttttccagaa
    15841 ccagaaggac cgataaatac atagcaataa ttcattgtca tttctccttt gatgattgaa
    15901 caagtgaaaa agctttggaa aatatttcca aagcttttaa aagtaacttt gcttttttgt
    15961 attttatacc agcaagccag tcacaatagc acttaaaaag ctgactaaag tcgctgttag
    16021 caaaattttc aatccgtgtt ttgcgacaag atttcctttt tcttcattta atcccttcat
    16081 cgcaccagaa atgatcccga tagaagagaa gttggcaaat gaaacgagga agacagatat
    16141 aattgctgtt gtacgctcag taaaatggaa attaccattt gctaattctg tcatagcaac
    16201 aaattcattt gtaaccagtt tagtcgccat gatactaccg gcatccactg cttctttcca
    16261 tgggattccg ctgatgaagg caagaggggc aaagatgtaa cctaggatct cttggaaagt
    16321 gatgccgaat atcccgtgga agatagcatt gatcatggca atcaaagcaa caaaaccgat
    16381 aagcatagca gcaaccgtga tcgccacatg gaaaccatca agaatgtatt ctcccaacat
    16441 ttggaaaaat gtctgttctt tgttttcttc aatgatcagc tcatcttctt tttcttctaa
    16501 tacataggga tttacaattg aagccagaat ataaccgcca aataagttca aaacaagggc
    16561 agtgatcaca tatttagaat cgatcagtgc catataagat ccgacgatcg acatagaaac
    16621 tgtagacata gccgatacac tcatggtgaa caaacgtttc tcagatagga agggtaattc
    16681 cttttttatg gaaataaaaa cttccgattg tcctaaaata gcagaagcta ctccattata
    16741 agattccaat ttgcccatcc cgttgatttt acttaatcct agaccaacag ctttcataaa
    16801 taatggaaga atcttgatat agcgtagaat accgataata gcagaaataa atacaattgg
    16861 catcaatacg gaaagaaaga aaggtgcact tcctttattt gctacaccgg caaaaacaaa
    16921 gtcaacacct tgcccagcaa aagcaagaag atgatcaaac atttttgcca atacagaaac
    16981 aaccgctgta ccaaaagttg tacgtaataa tacgaaacca agaacaagct gtaaaacgaa
    17041 catcacaatt agtggtttca atttgattgc ttttttgtta ctgctgatca aaaaagcaag
    17101 ccctaatgtg acaaataaac caataatacc taataaataa ctcaaataat cactcctatt
    17161 ccaaattccg ttttatttta cctgttttgc aaataaaata ctaatcttta gtgaaatttt
    17221 cattactttt ttagagtgaa acgcattcat tttccattag aaaataaagc gaacaaaata
    17281 aaaggtttaa aaagtgtaac gtcttagtaa agtctataaa aaaacgaaac tatcgattaa
    17341 gctaatagtt tcgttttcaa catttataag taaacttttt ctattggtaa tatagatttt
    17401 cggaagggta gacaggtgcg caggtaatat cgattcctag ttttttcaat gtttgttcat
    17461 catttttatt gaccatcaca gtagagtggg cttgtgctcc ctcaagttca gctagtttat
    17521 cataagcaac ttgagcgatt ggattcgtta ctgcactgat tgataaagcg atcaagactt
    17581 cattgatgct tagtgcatcc aaagaggaat gaagtgtctt tgatttcaat ccttgtattg
    17641 tttcaagaac taatggtgac aataaaggaa tgtcatctgc gatatgggct aaatgtttta
    17701 ctgcatttaa gataactgcc gctgacgcat ccatcaatga acttgtacgc ccggtaatga
    17761 tgacttcatc tggtaattcg attgcaatca cagcagaagg atcttttgta ggactttgcg
    17821 cttgaatctt atctgcatag tcatgggcag ggactaccac gtttcggtct tcaggacgta
    17881 aaccgacttc ttccataatc agtttgattc gattaactgc ttcttcgtcg atcaatcctt
    17941 ttttgaagtc gcattctgtt tggaaataac gacggatgat ttcttgttta gaggcttctt
    18001 ggacaacggt atcatccacg atcccaaatc ctacacgatt cacacccatg tcagtaggag
    18061 attgataaac agattcttta ccagtaattt tttcaataat acgtttgatt acaggaaatg
    18121 tctcaacatc ccgattatag ttcacagcta ctttattgta ggcatcaaag tggaaggaat
    18181 cgatcatatt gacatctttt agatcgactg tggctgcttc ataagcaatg ttcagcggat
    18241 gtttcaacgg aacattccat actgggaaag tttcgaactt ggagtaacca gctgcatgtc
    18301 ctttttggct ttcatgatac agttggttca agcaagtagc gagctttcca cttcctgggc
    18361 caggagctgt cactacaacg attggtttag ttgtttcaat atactcattt tttccaaaac
    18421 catcttctga gacgattttt tctacgttga ctggatagtc ttcgatttct gagtgtttat
    18481 agaccttgat gtttcgtctt tctagtttat tgataaagac tttcgtggca ggctgtccac
    18541 tatagcgagt gataacgaca ctgttgatta ataagccata accacgtaat tcatcgatta
    18601 accgcaagat atccatatca taagtaatcc cataatcacc acggatctta ttacgttcaa
    18661 tatctccagc atagacgcaa atcagtattt cagcttgatc tttcaatttt tgcagcaatt
    18721 tgattttcgc atcttcttca aatcctggaa gtacacgttt cgcatgcttg tcgtcaacta
    18781 acttcccacc aaattctaaa tataatttgt catagtggtt cactcgttcc aaaatatacg
    18841 ctgactgctc ttcaatatat ttttctgaat caaaaccaat ttttttcact aggttccctc
    18901 cttaagtact aaagcatttt ttcatttttt tgaggattcg tcaactggaa gagcgaaatt
    18961 cctcaaaaaa acaaagaaaa tggtttaaac caacttgtct agatagttat tcattggtat
    19021 gatagttttt gataaggaag gtgctacatg aaaaaaagac agaaaaagaa aaacgcatat
    19081 aaacactata tccgttcgat ttttaccggt tatgaaagaa tgcttgaaga tcccgaattg
    19141 gaacaattga cgtttactta tctaaacgaa gaaacgcagc taactcgtga tgagcatcag
    19201 cgcattcatt tcacaacaag agatctgcct agtaaataaa aaataagata aaggtcatcg
    19261 gattcgattc tgtcctatca gatggaaaga ctagttgatc gaaaaaaagg ctgtaccaaa
    19321 ttttggtgca gcctgtttta tggagcattg cccgctcttt tttataacaa ttttttacag
    19381 aaaatggtac tattgaagta ttaataagtg aaaaacagat gagtaagagg aggcaagtag
    19441 tatgaaagag ccagatacaa atgcaaatta tgagccagac gaactagagg agacgaacgc
    19501 ggatcaggat acaggacaag aatcgtcttc tttttacgat atcaaagaaa aagcaagcat
    19561 gaatctttcc caattattag aagacttaca ggcttttgaa aaagctgtcc gcgaagaaga
    19621 tatccctgag atctaccgtt tatacaatgg ccgattgaat gaagaattaa aaagaagctc
    19681 aaatgaaaat cacgagatcg atcaattgct gatgcgtaag atccatgatc gttttttaca
    19741 ggaatttcct tttatggaac aagtagaaaa catctcgcca acgatgagct attacaaaat
    19801 cggcacttat taccatgatc ggcccacggt cggtattgat gcaagtctgc cagaaatttt
    19861 tgttttgcct aagatcgatg aagagtggga gaaatattcc caaccggagt caacggacta
    19921 tgacaaaaaa atcaatgagc tagacgcaaa ggtgatcact gctcagacag aaattgaacg
    19981 tttagatgaa caaataaaag aaatcaatcg acaaatgact gatttgaacg acaataaagg
    20041 attcttgaat cgtaaaaaaa tcgaggaaga aattcaagaa ttagagaaga agaagcaagt
    20101 actatctaat gaaaaattag gctggcttcc ttatattgag acgcctgaaa caatccagca
    20161 gcaaaaagaa gcattgaagc aagaagcaag agcagaccag cttcgtgcag ccatcgtaga
    20221 aaaagaacaa aggcaaatca gacgctattt cggtagcaaa gagggattcg gtcaagcaat
    20281 ccatgaattc ttgatgaatt atcttggcaa tgagaatcct aataatcaat ctaatgaagg
    20341 aggttccgag tatgaatgaa cacgatgaag cagaatggac aaaaaatgaa gaacaaacag
    20401 aagatcatga agaaacgaac acttcattgg aagaacaaac aagtaatcct ctggatgaca
    20461 cagaagaaat ccctatgcta gaggaaacaa aaatacatga aaaagaaaaa gtaactccga
    20521 cgaatacgaa tactgcagaa aacacccatg cttacgaaat aactgaaaat cccgggtatt
    20581 tagaaggaaa agagcaagat catcaagata tcgtcagttt gattgaaaca gcggaagcag
    20641 aattagcgga tttacgtatg agaaaagatt tgatcgaatc agattttcca caattattag
    20701 aatcatatga tcgttttata ttgaatgaag aaccaatctc cacgatcgga aagacaagcc
    20761 tgatcgaata cttcacgtat gaattactga aaccgttgaa tgatattggt ctggaacggt
    20821 caaattcagc ttatgacaca tggaaaacaa gacatttttc gatcaattat acgttgaatg
    20881 gacaaaacga attagtcttt tcctttgtat taccgaccat cgatcaacga taccaagtgg
    20941 aatcgatgag tctcctaaac gtatcaccag agacaatgga aatcaatgtc caagatgacc
    21001 gggtgctttc tttgatccga cactggtcag tggatcgagt attctctgca gggcagatca
    21061 cgatattcaa tcacaaattg aatcaattat tagcccatgc aagaacactt ggttttaccg
    21121 ttaatcagac attactagac aatacgaagc cacttcgttt gaatcttcag agcgaatttg
    21181 aattgacgaa tgaagtattg gatgatattt ttatcgtggc aatgaaaaat ccatcctacg
    21241 atatggaaaa gatcaacgaa actacttatc aagtacgatt agataaagga cagtctttaa
    21301 cgataacaac aaacgaaaaa gatcaaacag tcttgtcgat ctcatctgga gactacccac
    21361 gatctgtcat tgatttcttt atcaattacg aattcttggt cccattaatg gtgagaaagt
    21421 cctgattgga taagttggat taccagatgt cattcagata attctgttcc aaaggacttg
    21481 cggcagttat ccagaataat tgtcacaagt cttttctgta tgtactaaat ggacgtgaat
    21541 aacttgctga tgaaggaggg atttcattag gaatgtccac aaataaaata gcacagctta
    21601 gcttattgtc tgctgcttgt gtagcaggta ggatcgcttt tcaatttatt ccgaatttcc
    21661 agccaatgac tgctattttt ttatttatag tactttactt aagcttaaaa gatgcgttaa
    21721 ttgtcatgag tctttctatt gcgatcagca gtttttattt tggtgttgga ccatgggtca
    21781 tcggccaatg gatcagctat actgttgttc tgagtttgtt ttcaatcgtc tgcttgagaa
    21841 aaacagtgca aaggaatcta tggttaaagg gagtctgttt ttttctggcg ggcatggttt
    21901 acggaatagg tatgaccgtt tttgatacgc tgttatatcg tttgcctcaa ccttggatct
    21961 attaccttca aggggtgtcg tttgatttga tgcacagtat aggcaatgtt gtgttctttc
    22021 ttgtttttct gccagtcgtc aaacgttttt acaatcattc aggaggaaaa aatgaaaaaa
    22081 ataatttata gtttgcttgc aatgagtgtc agtatactca ttttgacaag ttgcagtaca
    22141 acctatacac aatcggcttc caaccaaaag gaggaagtaa aaacatcgca aaaagcaaca
    22201 atcacgttac aagaaaatgg tcaaaacttt tcggaaaaag aagtggtctt caaaaaaggc
    22261 gatgatttac tgagtatttt gaaacgaaat tttgaagtca aagaagataa cggcttcatc
    22321 acttcgcttg aagggcactc acaggatgag aaaaatcaac tctattggat gtttactgtg
    22381 gacgggaaaa gtgctactac tggtgccaaa gagatcaaat tgaatgatgg acaatcggtc
    22441 attttcaatt tgtctaaact ataagtttca taaaaaactg ttaaagggcg aatattgcca
    22501 taattcagtg agttcagttg atgaaagaag gaaaataaca tggaaaattt taaaaaaagc
    22561 ggaatgtttt ccgtaattgc tgctctaggg gctaatattc tagttgctat cagcaaattt
    22621 gtcggctatg caatcagtgg cagtgccgcc atgctaaacg aaagcatcca cagtatcgtt
    22681 gattgcagca atcagatttt gctgttattc ggtgataaac aagccaataa aggacagagc
    22741 gagttgcatc aatttggtga aggacgagca aaatactttt tcagtacaat cgtcgcaatg
    22801 atgcttttct tcggcggtgg ggcacttggg gtgatggaag cttttgaaaa gttgacgcat
    22861 ccatcccatg aagtgggtaa tccgatcatt gttatagcaa tactgttatt tggtttggta
    22921 atcgaaggaa gttcgttacg cgtggcaatg aaagaaatca aagaattgaa tactgaaaaa
    22981 ctttccacga tgcgcttttt gcgcgaaagt cgacacagtg aaatactgat tatttttacg
    23041 gaagacttgt gtgctgtaat cggtttggtc ttggctttag caggaacaat attgacttat
    23101 gcaaccggga ttgctgcatt tgatgcgatc agcggattgc tgatcggttt cttgctgatg
    23161 ggagccgcca ttttcctagc aaaagaattt tatagtctga tcatcggtga aagcgtgaca
    23221 gcaagcgatt tatcaaaaat caagttagct tttgaacgtc ctgagatcag tcggctgatc
    23281 gatataaaaa cagttcattt aagtccaacg gagattttag ttgcagcaaa agcagatatc
    23341 gttggtaaca aagagaatga agcttactcg gtcatcaatg atattgaaaa aaatatgcgt
    23401 cagtctcttc ctgacaagaa gatgtatata tacattgaaa cagataaata tgacccaaat
    23461 tattctcgta aataaaacgt ttattcatga attgaagcaa aaatgagaaa aatataatct
    23521 tgtttttaaa taaaacggct acaatttagc gaatttatgt tacaatgagt ccgctgttta
    23581 tttgttgtaa ttaaaggaga tattttaatg aacaaaaaga aaagtgcgcc atggcttcaa
    23641 gctttgcatg cagtgatgcc actttgtata agctatatac cagtaggatt agcttgcgga
    23701 gtattgttgc aaaaagttgg atttgatcct ctcttatcag gactgttatc gattctggtc
    23761 ttttccggtg gcgcgcagtt tttagttgca tctatgctta cgacgcaagc atcatttgca
    23821 acgacattat tgatggtttt ctttttagaa ttacgctata cattattagg agcaagtctt
    23881 gccggtttta tgaaaaaaga aaagcggacg tttttggctg tcttttctca atcactgaat
    23941 gatgaaaact atgcggtgaa ctacttaaag ttttcaactg acccttcctg gaataaaaga
    24001 aaggctttat atgtcaattg gttctcaatg actgcatggg ccggtagcaa tatgatcggt
    24061 aattttttcg gctcggtgat tcgagtagat gctgaccttg tccattttgc tttgacggcc
    24121 atgttcattt tcatgtttat catgcagatg aaaagcgcac tactgatctt tacaggttta
    24181 ttctcaggcg tattaggggt cgtattcatg gtattattcc aaaatacttt cggattgatt
    24241 gcagcaacag tcattgcttc atttgccgga tttatgctgg agaaggcatt caaaaaagaa
    24301 aaagctaaga aactaagaga ccgcggtaaa gatgtcaatg agccgctctt caacttcccg
    24361 gaacaggagg ccaatcacca tgactaaact atatttgcta cttttagttg cttgtctgtt
    24421 catcgtggca tatatcccgc gcttgttccc gatgctttat tttactcatc gaaaagtgcc
    24481 atcctggttc agtgactgga tgaaatatgt accggtggca ttatttgcgg cgttagcttt
    24541 taaagatgtt ttcattactc atgaacatct ggatattgct tggaatatca aaatagctgc
    24601 aatgattcta gtagcaggcg tggcttacaa aacacgttcg atggcgttgt cagttttgac
    24661 aggacttgcg tctgtctttt tgctgtctat gctttaaact gttttatttt attaaaaaca
    24721 gagattgcga cataagttgt tcaaactgat ctatccgaac tgcatttgca acagtcaatt
    24781 ctggatgcaa gtttattcgt agggataaaa aagattagtg ttggcttatg atgcaagctc
    24841 ttttttattt taggaattag agagggattt gtccttctat gattttttgc tataataggg
    24901 aagatgttta ttttatgaaa gaatagttga gggaatttaa atgaataaaa aattgatgca
    24961 aggaacattt tggctaacct ttgctaatct tctatgtaaa gttttagggg tagtctattt
    25021 gattccctgg ctaagtatga tggggaacaa tcaagatggt atgcttgcta cgacattgta
    25081 taatgttggc tatcttcctt atggattgtt cctgatgctt ggtacagtcg gatttccaaa
    25141 tgcgattgca aaaaaagtag ctgtagccac aaaagaagga gataacgctg cttgtcggct
    25201 gatttttaga agtacgatca atatcatgtt tgtcatcggt atcgcctctg ctgcactgat
    25261 gtatttattt gctcctttac tagccggaat cagtccgatt gctaacgtta ataatgggat
    25321 actagctatc agaagtttat gcccatcttt gattgctatc ccaattctta gtgcaatgag
    25381 aggatatttc caaggaaaaa atgatctgcg gccttatgga acttctttga ttatcgaaca
    25441 ggctgtgcga gtgatcgtta tcttggctgg tacttattac ttgcgcgtat tgactgacgg
    25501 aaccatatta gaagctgtat tgatcagtac agtcgcttct ttcttcggtg ggttagctgc
    25561 gattatccat atgtatatcg tcggacgcag aaaagacttc ttcgaactta aagatttttt
    25621 gatttccagc cgttatttcg aaagagaaaa ccgatctgcc tctgtctcta tcattcggga
    25681 aacactaccg tttatttttg tcggctcagt cattactatc gttcaaatga tcgaccaagt
    25741 aacgatgaaa ccactgcttc actttttccg tccagagatc gcagatcagc aactggaatt
    25801 cttattcagc cgtgcttctg tcaatccaaa taaattgaca ttgatcctga tctccatggt
    25861 aggaacagta gctataagca gcttgccaat attaagcacg atgaagaaaa aagatcggat
    25921 acaaatcgaa aaaacagtag gagatagttt ttcgattgcg ttattgattc ttcttccttc
    25981 attgactgga atgtctttat tagctggacc actatacaca ttgttttttg gctatgatcc
    26041 tgaaagtgtc ggatatttcc aaatggcttt gctagcttct ttgtttttct ctttattcac
    26101 gatcctatct acgatgcttc aatctttgaa tcaccatcgt tttgcgatcc gattaactgt
    26161 agaagcaatt atcctgaaag tcatcttcca agtaatcgga ttaggattag ttggcggata
    26221 cgggatgagc ttatcaaatg gcttagcatt cggtattgtc tttgttcgcg gctatcactt
    26281 tatgtgcaaa gaataccgaa tagcaccttt agcaaagatc agcaattttt tcttaaaaac
    26341 tttccgctcc accctgatta tgcttgcagt atgttttgcc gttttctttt tgctgaatca
    26401 gcgattgtca atggaatcaa aaagctatgc aatgatttat tgtgtggctg taggaagtat
    26461 tggcggctta gtatttttat tttctcaatt cggaaaaaat gggtttcgaa tgttgaaaaa
    26521 tgttaaacat catagcagaa gcaaagaata ggttaactaa tcgttttttg ctgtcacttg
    26581 aaaaacggca actcgtatga ttacgcttgt cgtttttcta ttttccaatt ttagtttcat
    26641 atctaatctt acttatgata tagttataag gtctggaaaa attctttgaa acgaggaaat
    26701 taaacacatg aaacttgcag tagttacaga tagttcggca tatctgccgg aacgtatcaa
    26761 gaaccatccc gacttattcg ttattccaat ccctttgatt atggatggga aaatttataa
    26821 cgaaggaatc gatatcgaag cggatgaata ttatggactt ttaaaaaaca gtaaagattt
    26881 tcctactact tcacaacctg tcgtagggga agttttgggt ttatatgagg aattgaaaga
    26941 gaaagggtat gacacgattt taagtatcca tctttcttca gggatttctg gctttgtcaa
    27001 cacattattt gcgatgaaag atgacatcag cggagtaacg gtcattcctt atgactctaa
    27061 gatcactagt atgccgatgg gacacatggt agaagctgcc ttagacttaa atgatgaagg
    27121 tcagtccctt gatgaaatac ttgcacatat cgatcgaatc cgagataata cctatgctta
    27181 tctgattgta gatgatttga acaatttagt acgaggagga cgtttgacaa atggtgcagc
    27241 gctgattggc agcttattaa aaatcaaacc gatcctgaca ttttctgaag ggaaaattgt
    27301 tttattcgaa aaaatccgtt caagtaaaaa agcatttgct cgagctgaag aaattattgg
    27361 tagaagaaat aacgaaatac aaccgccagt caaactttac gtgatacatg caaataattt
    27421 agaagtagcg attgcggaga aagagaaatt gcagaaaaaa tatccaaatg cagaaatcga
    27481 aattggtcat ttcggaccag tcattggtac acatttaggt gaaaaagcca tcggcattgc
    27541 catttcagcg caataattcc ttttattcaa aaaacatacc aaaaatat
//
LOCUS       DACDAF010000029        27468 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.029, whole genome shotgun sequence.
ACCESSION   DACDAF010000029 DACDAF010000000
VERSION     DACDAF010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27468)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27468)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27468
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.029"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(266..466)
                     /locus_tag="IVZ69_001187"
     CDS             complement(266..466)
                     /locus_tag="IVZ69_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP8183289.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
     gene            complement(771..2003)
                     /locus_tag="IVZ69_001188"
     CDS             complement(771..2003)
                     /locus_tag="IVZ69_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP8183290.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            2257..2826
                     /locus_tag="IVZ69_001189"
     CDS             2257..2826
                     /locus_tag="IVZ69_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP8183291.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(3004..3444)
                     /locus_tag="IVZ69_001190"
     CDS             complement(3004..3444)
                     /locus_tag="IVZ69_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HAP8183292.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            3602..4366
                     /gene="map"
                     /locus_tag="IVZ69_001191"
     CDS             3602..4366
                     /gene="map"
                     /locus_tag="IVZ69_001191"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HAP8183293.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            4398..5321
                     /locus_tag="IVZ69_001192"
     CDS             4398..5321
                     /locus_tag="IVZ69_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HAP8183294.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            5397..6536
                     /locus_tag="IVZ69_001193"
     CDS             5397..6536
                     /locus_tag="IVZ69_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HAP8183295.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6529..7329
                     /locus_tag="IVZ69_001194"
     CDS             6529..7329
                     /locus_tag="IVZ69_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP8183296.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            7329..8156
                     /locus_tag="IVZ69_001195"
     CDS             7329..8156
                     /locus_tag="IVZ69_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP8183297.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            8134..8868
                     /locus_tag="IVZ69_001196"
     CDS             8134..8868
                     /locus_tag="IVZ69_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP8183298.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8968..9834
                     /gene="rfbA"
                     /locus_tag="IVZ69_001197"
     CDS             8968..9834
                     /gene="rfbA"
                     /locus_tag="IVZ69_001197"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HAP8183299.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9848..10420
                     /gene="rfbC"
                     /locus_tag="IVZ69_001198"
     CDS             9848..10420
                     /gene="rfbC"
                     /locus_tag="IVZ69_001198"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HAP8183300.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            10442..11470
                     /gene="rfbB"
                     /locus_tag="IVZ69_001199"
     CDS             10442..11470
                     /gene="rfbB"
                     /locus_tag="IVZ69_001199"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HAP8183301.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTSILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWQPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            11568..12419
                     /gene="rfbD"
                     /locus_tag="IVZ69_001200"
     CDS             11568..12419
                     /gene="rfbD"
                     /locus_tag="IVZ69_001200"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HAP8183302.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLPYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEALGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            12454..14487
                     /locus_tag="IVZ69_001201"
     CDS             12454..14487
                     /locus_tag="IVZ69_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183303.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFSLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMITFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFVALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            14531..15811
                     /locus_tag="IVZ69_001202"
     CDS             14531..15811
                     /locus_tag="IVZ69_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HAP8183304.1"
                     /translation="MKIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGVGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFTVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNTIGSSLMTLALLISGFASSFERWYVRIIGGIAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQVLLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYRWVPIIYILLAMAVHRYDEPEVTEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            16021..16827
                     /locus_tag="IVZ69_001203"
     CDS             16021..16827
                     /locus_tag="IVZ69_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183305.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16839..18059
                     /locus_tag="IVZ69_001204"
     CDS             16839..18059
                     /locus_tag="IVZ69_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183306.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGKVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            18049..19635
                     /locus_tag="IVZ69_001205"
     CDS             18049..19635
                     /locus_tag="IVZ69_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP8183307.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLYINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAQPQNSNYVKVLEVIQQTKQDEIIQQIPFNNFTGENETLSFHVSELA
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKDLPEFFLTDIAG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHYLIENNTRLD
                     QTLKTTINRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSLCIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVLREEVNQAKQLAEGAKAGFELRILCEK
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19674..21812
                     /locus_tag="IVZ69_001206"
     CDS             19674..21812
                     /locus_tag="IVZ69_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP8183308.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEVQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRQENGHISLATNSALEMAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDLIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPAEHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVHPGRISGFYEITYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYPNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTAMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(22180..23163)
                     /locus_tag="IVZ69_001207"
     CDS             complement(22180..23163)
                     /locus_tag="IVZ69_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HAP8183309.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            23541..24932
                     /locus_tag="IVZ69_001208"
     CDS             23541..24932
                     /locus_tag="IVZ69_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP8183310.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            24948..25988
                     /locus_tag="IVZ69_001209"
     CDS             24948..25988
                     /locus_tag="IVZ69_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP8183311.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRKIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            26007..27092
                     /locus_tag="IVZ69_001210"
     CDS             26007..27092
                     /locus_tag="IVZ69_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HAP8183312.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            27125..>27468
                     /locus_tag="IVZ69_001211"
     CDS             27125..>27468
                     /locus_tag="IVZ69_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAP8183313.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSS"
BASE COUNT         8838 a         4555 c         5538 g         8537 t
ORIGIN      
        1 tttccttcca tcagcataaa agttcacctc aaaaagagta tacgaacgaa tgttcttttt
       61 gtgaaggcgg aatttaatat actgaataat agaaaacaag tacttgtgcc aaattatgtg
      121 ccaaaaaaat tcgaattcaa caaaatgtaa acaaatagaa aaccttctat attaagattt
      181 cctgcaataa caaacacaac agaagacgtg taatagttag tcaggaacgt acaaataacc
      241 cctgtatcct ttgcggtaca gggggttatt ttgtataagt agacattgta gtttctaaac
      301 tgctatgtcc taaacgtttc gatacgctaa gtatatttac tccttgataa agtaaaatag
      361 atgcatgcgt atgtcttagt ccatcaataa acagtcgaag agaaaatagg gaaaaattga
      421 ttactaaaga aaaacttact aggtcgacgg tgtagttgat tttcatactt caatagattc
      481 gaattaaacg atttcgattg gcttatacca gtcctatcca acgaaagata tatcgttctt
      541 aactctagcg gtataacttg aagctttacg taaagccaat gggaatgaac tggagatgac
      601 tttttattat ttttagtaat agctgatggg ttaatactta caactttcct tttcaaagta
      661 ccatataaaa aaacggtggg gttgtttagc gaaataaagg atctaagcca atagcttaga
      721 tcctttattc tatgctttat attatttttt gcatgtgtgc gaaagtatac tcaagcccaa
      781 tcgccgtttc ggaaaatcgg tactgtagag ccatcttcac ggattccgtc gatatccatc
      841 ttgtcagatc ctaccatgaa atctacgtgg gtttgacttc tattcaatcc agcttctgct
      901 aattcttcat cggacatttc tgtaccgcct ttcacactga aggcataagc agaacctagt
      961 gctaagtgat tcgatgcgtt ttcatcaaat aatgtattga aaaagatgat gccagattga
     1021 gaaataggtg aagggtcagg tacaagtgcg acttctccta aacgacgcgc accttcatct
     1081 gtatcaagca gttttgctaa gacatcttct ccttgttcgg cagaaaaatc aacaactttt
     1141 ccatctttaa aagtaaattt catacccgag atgatggtgc cagcataact cagtggcttt
     1201 gtacttgaaa tgtaaccatc tactcgatga ctgtcaggtg ctgtgaacac ttcttccgtc
     1261 ggcatatttg ccatgaattt ttctccacga gcattatagc ttccagcgcc ttcccaaaga
     1321 tggtttttag gcaatccgat aatgatatct gtaccgggag cagtatagtg aagggcagaa
     1381 aattgttctc gattcaattc ttctgctttt tttgctaatt tttcatcatg cttcttccat
     1441 gctaagacag ggtcttcttc atagacacga gtcgttttga aaatctgatc ccataatgcc
     1501 tcaacttgtt tttcttctgg cagttctggg aagacttttg ctgcccattg tttaccagcc
     1561 gcagccacga cagtccaact gactttattt gcttgagttg ccttgcgtaa attcattagt
     1621 gctttgccat tcgctgattg ataagacgct actcgatggc tatctacacc agcaaatgca
     1681 tcgggatcgg cagaaacaac gctgatcctg cttgctcctt tttcaagcca ttcatccgct
     1741 tgatcgattt tagattgtgg tacattctca atacgatccg ttgcagcatg taaaagaaat
     1801 tctctttgga tctggtcgtc agtccattga acgataacct cagcggctcc tagtttataa
     1861 gcttcttgtg tgatcaatcg agcaaggggt gcctgttcca cgctgatctg taaaacaact
     1921 gtgtgtcctt tttctgtggc tacgccagtt tctgcaatta agcgtgcata tttttttaga
     1981 agttcattaa aatcagataa cataataaaa attcctcctc accatttttt ctggtaacta
     2041 ttagcatgat accatttaat tatgattcaa acaatgaggc tttaaataaa aaaaggaggt
     2101 tattttttta aggttaagtt tcatgatata tgttactact tgctatttca gcttgtgaag
     2161 aaaatcaaaa actaattttg catatcaaaa aaacatgtta caatgaaatt aatcaatggt
     2221 ggaagcgtta taaaaaaatt aaggagatta aaaaatatgg caagaaaaaa gacgattact
     2281 agagaacaga ttttggcagc tgcttatgaa gtagctgcca ccgatggatt tacacgattt
     2341 actgcgagaa acatcgcgaa caaaatgaat tgttccacgc aaccgattta tcttgagttt
     2401 aaaaatatgg atgacttgag acaagctctt tttgagcaga tctatgatca tttacaatat
     2461 gaagtgttca ctgttgagca tacagggaat acgattatcg atcttgcttt taattatatc
     2521 cattttgcaa gaagagagaa gaagttgtat cgttcactgt acttagaaga atatggtgga
     2581 ggaaaagaga tgcagaattt ctcttatact tactttgtga atacagtgaa acgcgatcca
     2641 gcttatgtga atctttcaga agagcagatc gaatctttgt ataatgggac atggatcata
     2701 gctactggga tcgcagcttt gatgtcttca agcatcatcc atccaactga tgaacagatt
     2761 gaaaagatga tccaagacag tatagatgct atcttgaaat tcaaagaacc aatcgaaatc
     2821 gattgaatat actcaaaagt tccacaaatc agtaggtaac aagagatgtg tcaaaataag
     2881 gaaaagttcg tttttcttac agcgtatgca tttttaactc ccgaagaact cttccatgaa
     2941 tgcaatgaat aaaagagcca tacagattga ataaatctgg atggctcttt tattgcaagt
     3001 atattaaatt tttgcgacta gttctttagc gaaagcttct aaattttcga tatcttcttc
     3061 ttcagcattc agatccactt taacattttc ggctcctttt gatgcgcctg tttttgcaaa
     3121 agcagcatcg aaatcatcca ccgatttgca gaattcatcg taaaaagtat caccagatcc
     3181 gcagacaccg taaatttttc ccaatagatc caattcttgc aagtcttcat aaaagtctac
     3241 gatctcatca ggcagatcgc catcatcgta tgtataagta gctactacgc aaatatctgc
     3301 ctcctcgaat tcatctgcat ctacttgggt acattcgttg atttcgactt cgatatccag
     3361 attttcaaat gcttctgcaa caatatcggc gatttcttca gtgtttcctg tcatgctagc
     3421 atatacgatt tttgctaaag ccatgatgtg cctcctcgtt tataattatt taacaattat
     3481 gaattatacc aaaacatcat tgaaaagaaa ataaaaccta aagacacctg gggaatgtca
     3541 tttggctaaa tgtatgccgc tatgttaaaa tgagagggat ttgtaaaaag gagacgaaaa
     3601 tatgattact ttaaaatcag cacgtgaaat tgaaatgatg gcagaatctg gagctttatt
     3661 agcagatgta cataaaaatc tgcgtgattt tataaaacca ggaatcacaa gttgggatat
     3721 tgaggtattt gtcagaaact atatcgagag tcatggcgga attgctgcgc aaattggctt
     3781 tgaagggtat gaatatgcga cttgtatcag tataaatgat gaaatttgtc atggattccc
     3841 tcgtaaaaag cctttgaaaa acggtgattt ggtaaaagtc gatatgtgta tcgatttgaa
     3901 aggcggcatt tctgattctt gttgggccta tgtagttgga gaatctacac ctgagatcga
     3961 ccgattgatg gaagtaacga agaaagcttt gtacatcggt attgagcaag cacaagtagg
     4021 gaatcggatt ggtgacatcg gtcatgctat ccaaacttat gtagaaggcg aaaatctagc
     4081 gatcgttcgt gattttattg gtcatggcgt tggtcctacg attcatgaag aaccagcagt
     4141 tcctcattac ggagaagctg gaaaagggtt gcggttgaaa gaaggcatgg ttatcacgat
     4201 cgaacctatg gttaataccg gaacttggaa aatgaaaatg gatcctaacg gctggactgc
     4261 gtatacaaga gacggcggac tttcttgcca atatgaacat acattggcta ttactaaaga
     4321 tggtccaaga attttgacat cacaaggaga agaaggcact tattgatcta tccagtcaat
     4381 aggtacggga gaggtacatg aaagtttgga acaaaataaa acaaaatgaa aatctgatgc
     4441 gctttattga gacgactcaa aagcgcatca ctgattcaga aatgagtacg acctctgtcg
     4501 tcgttgctta ttatttactc ttgtctttat ttccattgat tattgctttt ggtaatattt
     4561 taccgtttct ccacatcgat caagagactg tactgaccta tttacgagaa gtgattcctg
     4621 agaccgttta ccagtttatc ggtcctgcaa tcaaagacct tttgacacaa agttcaggag
     4681 gcttgttatc cgtttctgca ttagcggctt tatggtctgc aagtcaaagt atcaatgctt
     4741 tgcaaattgc gatgaataaa gcgtatggcg tagaaaatag aaaaaatttt ttgatcgtcc
     4801 gtttcttctc actaattgtc attgtcttgt tcatgattgc tattagtggg gtaactatcg
     4861 ttcttgggtt gggacagctg attttggatg ctattcagcc aatcgtacaa atacccgtga
     4921 actttatcga tcagttccaa actttgaagt ggccaatcac attggtagct ttatttgtca
     4981 tcatgttctt gatttattta attgtcccta atgctcagtt gaagttgaag acgatcattc
     5041 cgggcacgat cttcgctact gtcggctgga tgctgttatc acaagtgttt agtatctatg
     5101 ctaggtattt tgcaacgagg atcagcggtt atcagatcat aggaagtttt attgtactca
     5161 tgctttggct taattttgct gctacgatca tcattttggg cggaatcatc aatgcagttg
     5221 ttcaagaata cgtgacgggt catcaaatca aaaaacgtcg agatccaagc cgaaaatggt
     5281 tcaataaatt gaaaactaaa ttttctcata aaaaaaagta gaaacaagag ttcttattgt
     5341 aaatttatat cagtaattta taataattat gactcttaat taaagtaggt gcccatatgc
     5401 ttgtttcttt tagtatggtt ataagatttt ttctgacaat tttattatca ctgatattaa
     5461 cacctgtatt caaaatcatt tcagtacaaa caggtatggt cgacaaacca aatgaaagaa
     5521 gaataaataa agttccaatg ccttcagcgg gcggactgcc tatctttatt tcatttgtta
     5581 tatcgacttt attcttattc cgtaaaatta tccctcaatc gtatattgta ccgatcttga
     5641 ttgcttcttt agtaatcata gtcacaggag tgctcgatga taaatatgag ctgacaccta
     5701 aacaaaaaag tatagggatc ttgattgctt ctcttattat ttattttgta gcagatatac
     5761 gtattgattc cttcacgctt ccttttattg gatatatcca actaggctgg cttagttttc
     5821 ccgtaacgat tttttggatc ttcggtatca cgaatgcggt caatctgatt gacggtttgg
     5881 atgggctggc ggcagggatt tcattgatcg gtttaattac gataggaatc attggatatt
     5941 ttttcctcca tgcttctaca gtgtatattc cagttgttat tttctgtctt gtagcaagta
     6001 ttatcggttt ttttccttac aatttttatc cggcaaagat ttatttaggc gatacaggag
     6061 ctctattcct agggtttatg atggccgtcc tttcactaca agggctgaag aacgtgactt
     6121 ttgtttcatc gatttctttg ctgatcgtca tgggagtgcc ggtaacagac acgttttttg
     6181 ctatcattag gagaaaagca aaccgtgttt ctttttctac agcagataaa aaacatcttc
     6241 atcaccgact aatcagttta ggctttactc ataaaggtgc tgtcctgacg atttatgcga
     6301 tggctttgat gttttctttc acagctatgg tcatgaatta tactggaaga atcggaacga
     6361 tcatattgat tattgccatg ttgtttgctg caattttatt atttgaattg attggtctga
     6421 tcaatgagaa acatcagttt attttaaaaa cattgcgatt tttagggaat aaagagtacc
     6481 gtacgcaagt aaaacagaaa tatttgaaga aatggaaccg tcatatagat gaataacaaa
     6541 ttaaaccagc cgatccttat tagtattgtg acggcaaaca gtgataaaat ttttcggaca
     6601 ctagataatt ttatttcaac tgtaaaagat gaaacagcag taaaaatccg aatttttgac
     6661 aacaattcac ttcccgagta caaaaaaaga ctaacagagt ataggaaata tccctacatc
     6721 gatatctatt ttcatgatga aaattccgga tttggttatg gacataatca caatctgata
     6781 gctagcgatt ctcgctatgg cattatttgt aacccagata ttttagtgga tgaagagaca
     6841 gttacagcat tggtcttgtt attgaaagaa catccggaat gtgcgatgtt agcacctaag
     6901 attcttaatg aagatggaac aactcagcac ctcatccgtg agcagctggc tgtttttgat
     6961 tacgttttgc gctttgtgcc tttcaaatgg gtcaaaaaaa agtttgacaa acgactggct
     7021 gtgtttgaat gccgaggatt gcctactgat gctaatagtt atgtacggat gatctcaggt
     7081 agttttatgg tagctgatat tgataaattt aaagagataa aggggtttga tgagcgtttc
     7141 ttcatgtact ttgaagacaa cgacttgtgt ttgagttttg aaaaagcagg ttacaagtta
     7201 ttgtacacac ccttttatgc agttatccat ttttacggga agggtgcgca tcgaaatgca
     7261 aaactgtttc gcgtgttttt gacttctatg atgaaatttt tcaataagtg ggggtggcgt
     7321 tttttctgat gaaaccagaa atattagtag tcgttgtgct ttatcagcaa ctattcagtc
     7381 aatctccagc ttatggacca ttaagcaaag cacttagcga aaagcaaatt cagcttatta
     7441 tttacgataa tagtcctcaa aggcagcaaa atgagctgtt tgaaaaagaa aatatcgttt
     7501 atcatcatga tccgcaaaat cctggtttag cggtggctta taattttgcg ttgtctcaag
     7561 cagatgaagg aacacgttgt ctcgtcactc tggatcagga tacgaggcta gtcgacgatt
     7621 attttgaact attgcgtaaa gtaaccttta cagatgaatg tgttgctgca gttccgatga
     7681 ttttttctgg gagccgacaa gtttctcccc tatattcaga tcgttatatc aatcgtacag
     7741 ctcaagcagt agaagttgaa ggcccaacag ctgaacgaat catggcaatc aattcaggtg
     7801 ttgcctggtc tgtcaaattt ctaaaaaaga ttggcgggtt taatcctgct ttttctttag
     7861 attttttgga tcattggctg ttttggaaag tggatcagtt ggaaaaaact gtggagatcc
     7921 ttcctgtacg aatggaacat gatctttcgg ttttagacta tgaaaaagtt tcaagtaatc
     7981 gataccgttc tattttacaa gcagaaaatc gattttatca tgaatatgat caaaggcatt
     8041 tatccagtca ccgacgacaa ttattgttaa gaacagctaa acagttcttg accgtcaaaa
     8101 accggcatat ctggcggatg actttgcgct catatgttaa gaattggaag gtgtgaattc
     8161 gtgcgttcgg tttgtatagc tacctttaat ggaggcagat atttaagaga gcagttagat
     8221 agtattttat ctcagctttc agcagaagat gaagtagtca tttctgatga tgggtcagta
     8281 gatgatacat gggatatatt aactgaatac gcagaaaaag ataagcgaat ccagcttttt
     8341 tcggggcctc gtcaaggatt gatcgctaat tttggttatg cgatccagca gacgaaagga
     8401 gatctaatct ttttggcaga ccaagatgat gtttggttgg agacaaaagt gaaaaagatc
     8461 actgactatt ttgagcagaa tccggatcag ctagtagtag tttctgattt aatcattgtg
     8521 gacagcgagc tgcaagagat ccatgattcg tatttttcgt ttcgaaattc caaagaagga
     8581 tggcttaata atgtgataag aagtcactat attggtgctg gtatggcttt ccggtcttct
     8641 ttaaaacccg atattttgcc gatcccgtca gaagtgccga tgcatgatat gtggattggt
     8701 ttgctgggag gaaagaagac tgggttccta agagaaccgt taactctgta ccgaagacat
     8761 gatttaaacg cgagtgagat tgaaacacat tctaaattac ggcaaaaaat ttcttggcgt
     8821 gttcatctga ttacggcgtt gatcaaacga aaatggttta aacgttgata aaagatgttt
     8881 aaatccttaa tatttccatg acaaatataa caattgatga gataataaca aagtgaaatt
     8941 tgaaatcaaa aaggagagca gatatccatg aagggaatca ttcttgctgg gggcagcgga
     9001 acacgtctgt accctttaac aaaggcaaca tcgaaacaat tgatgccgat ttatgacaaa
     9061 ccaatgattt attatccaat gtctactctg atgttggcgg gaatcaaaga aattctgatt
     9121 atttcaacgc cacaagatac accacgtttc aaggaattat ttggaaacgg aaatgattta
     9181 ggactgcaga tcgaatatgc agtacaagaa agtccagatg gattggcaca agcgtttatc
     9241 attggagaag aatttattgg agatgatagt gtctgcttgg tattagggga caatatttac
     9301 tatggtggcg gtctgtctaa aatgttgcaa cgagcagctt caaaagatac aggcgcgaca
     9361 gtatttggct atcatgtcaa tgatccagaa cgctttggtg tagtagaatt tgatgagaat
     9421 atgcaagctt tgtcgattga agaaaagcct gctcagccaa aatcaaatta cgctgtaact
     9481 ggcctttatt tttatgacaa tgaggtaatt tctatcgcta aaggtatcaa accttcagaa
     9541 cgtggagaac tagagattac ggatgtcaat aaagcatatt tggataaagg aaaactatcc
     9601 gtagaactta tgggacgcgg atttgcttgg cttgatacag gaacacatga atcattgctt
     9661 gaagcatcta cctttatcga aacaattgaa aaacgtcaga acttaaaagt ggcttgtttg
     9721 gaagaaattg cttaccgtat gggctacatc gataaggaac aattgctggc ccttgcacag
     9781 ccattgaaaa aaaatcaata cggtcaatat ttattgaatt tggccgctga ataaggagtc
     9841 cttacagatg aaagtaacag atacaaaatt aacagatgtc aaaatcgtag aaatggacgt
     9901 ctttggcgat catcgcggtt tcttcacaga aagttattca aaagcaaaat ttgcagaaca
     9961 tggattgaaa tatgactttg ttcaagacaa ccattcacta tcagctgaag ctggtgtcct
    10021 tcgggggctt catttccaaa aaggagaagc tgcacagaca aaattgattc gggtagtcac
    10081 tggagcagtt ttagatgtag tagtggatat ccgcaaaggt agcccgactt atggtcaatg
    10141 ggacggattt atcttatctg aacataatca tcgacagttg cttgtaccta aaggatatgc
    10201 ccatggattc gttactttga caccaaatgt gaacttcctt tataagtgtg ataattacta
    10261 taatgcagaa gcagatgggg gcatcgcatt tgatgatcca gatttagcga ttgattggcc
    10321 aattgatcca tcaagagcga ttatgtcgga aaaagatcac cgtcatccga cattaaaaga
    10381 atttgaagca gaaaatccat ttgtttacgg agaaatctaa gaattaagga gaaattttct
    10441 tatgaaaaac atcattgtta ccggaggtgc cggattcatc ggctctaatt tcgttcatta
    10501 cgtggtaaac aatcatccag aagtgcatgt cactgttttg gataaactga cttatgcagg
    10561 aaacaaagag aacttggccg gacttcctag cgatcgcgta gaattggtcg taggagatgt
    10621 tgcagatgca gaattagtgg accgtctagt aaaagaagcg gacgcagttg ttcattacgc
    10681 ggcagaatcc cataacgata attcattaaa agatcctttc ccatttgtac aaacgaatat
    10741 cattggtacg tatacacttt tagaagcttg ccgcaagtat gatgtacgct atcatcacgt
    10801 atctactgac gaggtttacg gcgatcttcc attacgtgaa gacctgccag gacatgggga
    10861 aggcgaagga gaaaaattca ctgcggaaac accatataat ccttcaagtc catattcttc
    10921 tacaaaagct ggttcagatc tgttagtaaa agcatgggtg cgttcttttg gcttacgtgc
    10981 aaccatttca aactgttcaa acaactatgg tccttatcag catattgaaa aatttattcc
    11041 tcgccaagta acgagtatct taagcggtat tcgtccaaaa ttatatggcg aaggaaagaa
    11101 tgttcgtgac tggatccata cgaatgatca ttcttcagca gtgtggctga ttttgacgaa
    11161 aggcagaatt ggcgaaacct atctgatcgg tgcagacggt gaagaagata ataagaccgt
    11221 gatggaattg atcttagaaa tgatgggcca accaaaagac gcatacgacc atgtaaacga
    11281 ccgcgcaggg cacgatttgc gttatgcaat cgattcgaca aaattgcgag aagagctagg
    11341 ttggcagcct gagtttacga acttccgtga tgggttggct gacacgatca aatggtacga
    11401 agaacatgaa gactggtgga aaaaagaaaa agaggccgtt gaagcagcat atgccaaaaa
    11461 tggacaataa tacagaggaa atttcactgt attaatggaa aaacacatgt gaggcaggcg
    11521 ctcgcctgtc tcttttttaa aataaaaatc aaggagcgga taaccatatg tttttattaa
    11581 ctggaggaaa tggacaatta ggtacagaat tgcgccattt attagatgaa aaaaatctgc
    11641 catatgtttc aacagatgca aaagacttgg atatcacaga tgctgagaaa acaatggctt
    11701 atattacaga attaaaaccc gatgttattt tccattgcgc agcttacaca gcagtagata
    11761 aagcagaaga agaagcaaaa gaattagatg agaaaatcaa tgtcgatggc acaagaaatg
    11821 tagcacttgc agcaaaagct gtgaatgcac aattcgtcta tatcagtaca gactatgttt
    11881 tcgatggaaa aaacaaaaat gtagaatacg aagtagacga ccaaacgaat ccactaaatg
    11941 aatatggtcg tacgaaatta ttaggcgaaa aagcagtaga agagatttta gaagactatt
    12001 atatcatacg aacttcttgg gttttcggga tctatggaca caatttcgtc ttcacgatgc
    12061 aacgcctagc ggaaacccgc gacaaactga ctgtagtaaa tgaccagttt gggcgaccaa
    12121 cttggacacg tactttggca gaatttatgg tatatgtcat cgaagaaaaa gcaccatttg
    12181 gtatttatca tttgtcgaac gaaaatagct gttcttggta tgagttcgca aaagaaatat
    12241 tgaaagatac agatgtagaa gttgcacctg ttacgtcaga agaatttccg caaaaagcaa
    12301 cacgtccgca gtattcagtc atgagcctga aaaagacaga agcgttaggt tttgtcatac
    12361 caacttggca agaagcactt gcgcaaatgc tggaagctgc caaaaaaatg aataagtaat
    12421 ttccttttta tcaaatagaa tttggagcat gatatggaaa aacaaacaag aagtgcacga
    12481 cgaaaagaaa agccaaaagc gaatcaggca gattcgaatt tggtgcttga cctgtttcta
    12541 aaactccgct atcttattgg cgttttagtc atcgtggtca tcgttacttt taatttaaac
    12601 ggaagttcac ttggtgtttg ggataaatat gtgtcgcaaa gagacgatgg gaaaaaaact
    12661 gatgtgattt ttggacagaa tcgggaagtg cggtcagacg aatggctggt gcagacacct
    12721 ttttacctct cacaagctga agaggacttt tcgttggtga acgaggatta ttcattaaac
    12781 ggacaaaaca tgatcattgc gtataattct cctgtaaagg atattacggt tatcggaaaa
    12841 ccattcaact ggggattctt tttcctcgga agagatcgag gactttcctt ttattgggcg
    12901 atgaaattag tcgtcatggt cttgcttgga ttcgaagtac tgatgatatt aacgaagagg
    12961 aaaaaagctc tatcgctaat cggtgcattt gcgctgacat tttctccagc agtccagtgg
    13021 tggttcatgc aacatgtggg cgatttgatt ttctttactt tgggactgat gattactttt
    13081 tatcattatt tctacaatca tgataaaaaa tggctacgaa cgttgatgat gcttttggtg
    13141 gttattttcg gtattgggtt tattttagtg atttacccag cccatcaagt gatgctggcg
    13201 tacttgctga ttttttattt tgttggcctg cttatttact atagcaagaa agtttcatgg
    13261 gatctgttgg atgtagtgtt gattggaggg gcagttttat ttattggcgg agtcatggtt
    13321 catttctggc taacgtcaaa agacgcattg ttagcttctt tgaatacctt atatccagga
    13381 aaacgggtaa gtactggagg aaagtggacg attggcgaat ttttttcttt ccttacaaat
    13441 tggaaaattc cttttgaaga tatcaactat tcgaataact ctgaagtggc cctgttctat
    13501 cacttttttc caactgtatt cctagcaagt ccatttgtgt tatttggcaa aaaagatagc
    13561 gaacaaaagt tactgggacg tattttgatg attttttgtc tgttttctat cttttggatt
    13621 accgttgggt tgccaaaatg gctagcagaa atcactctgc tgtcttatgt tcctccatta
    13681 agagccatcc ttacttttag ttttgcggct tgtttattat cgatctggtt tatcgcttat
    13741 atttggagag aagatgttat tcctatttgg tataaattca ttttgttggc agtaaatgca
    13801 tggtcttatt tctatgcgat tacgcattcg aaaatggata attatttttc ggattttgaa
    13861 accatcgcag ttgctgtgtt gggaacagtg attttagctt ttgcattatt tggctggaga
    13921 cgcttgtttt acctcgcttt tgtcgcctta gttatcgtat ctggcttttt cgtcaatcca
    13981 gtcgtagaag gtacaggagc gatttttgaa aaaacactgg caaaagaaat ccaaaaaatc
    14041 gatcaacaag atcctggtaa agtttggttg tctgaagatg aattatataa cttcacccca
    14101 acattgggag tgaaatcctt caatacagta cgcttttatc cagatatagc tgcatggaag
    14161 aaaatcgatc cgaaagaaga atacgagaag tattataatc ggtatgctca tacaagagct
    14221 tttatcgcta aggaagatac aaagttcatt ttagatcgtc cagatatgtt ttcggtcacg
    14281 ttgaattttg aagacgcaga aaaattaggg atcgactatg tgatcagtaa acgaccatta
    14341 actgattaca accaattata tgaagcgcag ttcacgcagc tatatggacc ggataaagac
    14401 ggttatatga tttttaaagt agaatatccg gattatccag atgtaccaca aacacaaact
    14461 caggaaaatc agctagtcgt acagtaatag gctagctgag aataatcctg aaatattagt
    14521 agaaaggaga gtgaagataa ttcaagcaat cgtacaaaaa tttgtcaaca aaatgagtgt
    14581 cggtttcttg cttttgttgc tgacgctagt cttttttgtt tggacagcag gggtaggttt
    14641 tccagcaact ttgtttatat ataacaatag ttcattactt atcgctttta gtgtggctat
    14701 tttgctcatt ttaaatgttt ataaagcaaa aggcgtcgat tttctttatc taggtgttgc
    14761 gcttgccctt ttcattttct tttcttactt tcgggaatta agaaatgagt ctttatttgg
    14821 agacttactg tttcctttga ttattttatt ttgtttagta attaaatgga tcgagtggac
    14881 aaaatgggat cgcggtattt atctgattgt ctttacggtc ttcctcggaa tcacgttata
    14941 tcgtgtattt acagagatcc aagtaccaga aggacaaagc atctgggctc caggcaattc
    15001 gctttctgat atttggatca atacgaatac aatcggaagt tctttgatga ctcttgcttt
    15061 attgatcagt ggatttgcca gttcttttga acgatggtat gttcgaatca tcggtgggat
    15121 agcagtcgtt gcagcctttt taggtatttg ggtctgccaa tctagaggtg cattagtcgc
    15181 gttgattgtt tttgcgatat tggatctttt acctaaatcg ttgatgcgtg tcattcgtgc
    15241 gccatttatt gcctacacgg ttacgattct tttagctttg ccgatttctt atctggcggc
    15301 tgtctctgaa aaagtcaatt tgtttaccgg tcgagaagat atttggcata aattctatca
    15361 gacgctagga gaaaaatctg aacaagtttt actaggaatg aaaacattta tcttccagcg
    15421 aggaaaccaa tttttaggaa accacaatag ttataattct attttgaata tctatggatt
    15481 gataggattt gggattgctg ctttgctgct tatccttttt attggtcgct taacgttgaa
    15541 agcagattta tccaacgggc agatgacttt tatctgggcc ttttttgcgg tgatgatgca
    15601 gtcatttatg gaggatacat tgacttcata ccgatgggtt ccgattattt atatcctgtt
    15661 ggctatggcc gttcatcgat atgatgaacc agaagttacg gaggaattct atgttatgga
    15721 agaggcatat gacgatatga cttatgatga tacatcttat gaggaacaac cagatagcgc
    15781 tcattcttcc aggatccaac gctatcattg ataggcacaa aatacgagag aggctgtgac
    15841 aaccgtcgca gccttttttg gtttattgca attgtctagc atcttctgta aaatagaaac
    15901 gttagagaaa atcttgtatc atagaaaatt aagaaagaaa taagaacgca gctcggtacc
    15961 aaaaatatgg taaaatggca cttgactgta attcactgaa aatcgcttgg aggaacacaa
    16021 atgtttaaag atttgtattt atttatgaag gacatttatc agaacagaaa attactgcta
    16081 cagttttcga tcaatgactt caaatcaaga tatgcaggat cgtttttagg aatcttatgg
    16141 gcgtttatca atccgctatt tactgtattg atttattggc tggtatttgg tgttggactg
    16201 aaagcacaaa tgatcgatgc aaaataccca tttatcgtat atttagttac cgggatgatt
    16261 ccctggttct tcttctcaga tgcatttgca tcaactacgg ttgtttttcg ggaatatact
    16321 tatttagtaa agaaagtcgt attcaatatt cgtatcttgc ccacgacgaa aatcctatcc
    16381 aatctgtaca cccatttatt cttcattctg attggcatag ctgtcgcgct tataaatggt
    16441 atatatcctt cagcaatgtc tttacagctg atttattatt tattttgcat gtgtgctttc
    16501 ttgacaggat tgacttggct gacggcatcg atccaaccat ttttacctga tatcatgcaa
    16561 ttaattacga tcgtgctgca gttgatcatg tggacattac cgatattatg gagccctaat
    16621 cagtttgatt caggtcttgt aagcatattg aaattaaatc cgctgtacta tgttgttcaa
    16681 ggttatcgtg agtcattttt aagtgaagct tggttctggg agcatggaac atatactttg
    16741 tatttctggg ttttcacgtt agtaatgttc gtaatcggct ctgcagtgtt ccgtagattg
    16801 aaaccacatt tttcagatgt gctgtaagga gaatagctat gacagaatat gcaattagac
    16861 taaaagatat cacaaaatct tataatatgt acgcaaaacc ttcggatcga tttcgtgaag
    16921 ccctcaatcc ttttaagaaa tcctatcatg atgtatttta tgcgttgaaa aacgtgaatg
    16981 tagaaataaa aaaaggtgag atgatcggtt tcgtgggaga aaacggatcg ggaaaatcta
    17041 caatgttgaa aatcattacg ggagtactga caccaacatc cggcacgatg gaaatcgaag
    17101 gaaaaatctc agctttgcta gaactaggat caggattcaa tcctgagtat tctggctatg
    17161 aaaatatcta tttaaatgga atggttctag gattttcaag agaagaagtc gatgaaatgg
    17221 tcgatgatat cattgaattt gctgacatcg gcgaccatat ttatcaacct gtaaaaacct
    17281 attcaagtgg gatgttcgtt cgtctagctt ttgctgtagc gatcaatgtg aatcctgata
    17341 ttttgattgt ggatgaagca ttggcagtag gagatcttga atttcaacta aaatgtatgg
    17401 aaaaatttac agaaatcaag aactcgggaa agacgatttt attcgtttct catgatatta
    17461 gttcgattcg ccgtttttgt gatcgttcct attggttgaa aaatggaaaa gttgtcgaat
    17521 atggtgatac gatggaagta acgacgaatt acgaaaactt tttgaagaaa aaatcagtta
    17581 aaacagtaga tcgaaataaa aaccaagtag aacgcttcgc agctccagat atcgtagacg
    17641 tgacgaaagc cgaattgttg gataaagata aaaatccagt ggatatgctg gaacaaggag
    17701 aaaaactata cgttaaagta acctatgaag taaaagacga tacaatcaaa aatccagttt
    17761 taggaattgc tctgcgtaca gtcgacaatt tttatgtgtg cggactcaat actctactag
    17821 atggtatcaa gatcccttgg aaaaaaggtg agaatatctt ttatctggag tatgaaaagt
    17881 taggtttgtt agctggtgaa tattattttg acgttgcggt ctttgaagaa aatgcaacgg
    17941 ttcctttggt atacaagaca aaatacatga acttgtttgt cagcggttct tatatcggag
    18001 aaggcatcgt ggtcttagac cataaatggg aagaagggac tcatagcaat gaaatatgat
    18061 tttgaaatgg acctagatga acaaagcagt gtgggaaaaa ttgccgcaca gatcaaacca
    18121 ggaagtaaag ttttagagtt tggtcctgga aacggccgat taacgaaaca tttgatcgga
    18181 gcaaaacaat gtgaagtgag cattgtcgag ctagataagg aattgttcga ttttgtcagc
    18241 gagtttgccc aagatggatt ttatggagat atcgaaagtt ttgaatgggc aaactattat
    18301 gctggacaaa catttgatta cgttttgttt gccgatgttt tagaacattt ggtagatcct
    18361 ggaaaaacgt tgaagaaagt tagagaattt ttgaatgaag aaggagaaat tctaattaca
    18421 ttccctaacc ttgcgcataa ttctgtcatg attgatttgt tcaataatca attgccatgg
    18481 gcttcttatg gtttgctaga tgaaacccat aattcttttt atactcatga tggcttccaa
    18541 aaagtttttg aaaaagcagg attatacatc aatattgaag attatttgta cttagctgta
    18601 ggtgatacag aattaaaatc aacttatgaa gaattgccgg aagctgtacg ttatgatttc
    18661 aaaatgcgac catttggcga agtctaccaa tacttcttct cattgatgaa acatccagta
    18721 gcacaaagtt ccattgcgca gccgcaaaat tctaattatg tgaaagtatt agaagtaatc
    18781 cagcaaacga aacaagatga aataattcaa caaataccat tcaataattt cacaggggaa
    18841 aatgagacac taagtttcca tgtatcagaa ttagcagaac gaatggtgtt tcgcttcgcg
    18901 cagcaaccta gctttatcga attcagcgca gaagctgctg gagaaaaact cacatttatc
    18961 gattcaaatg ctgtagtcaa aacagtaaat gattgttatt tgtttgatgg taaagattta
    19021 ccagagttct ttttaacgga tattgcaggg aaagaagtga ctatccattg tcactatcgt
    19081 tttatcggag aattgacacc aacaatgaaa gaattgctgg aaacaatccg tccaatggct
    19141 gaagttacaa agcagctttc tgagaaaaat gatgaattag aaagagaaaa tcattatctt
    19201 attgagaata atacaagatt agatcagacg ttgaaaacaa ccataaatcg ctattgcacg
    19261 ttgttggaaa gtgatgaatg gacaatcaaa catagattag ggcgacgtaa gaaagaaaca
    19321 tcgaaaaaaa tccaagaaaa agagctttct ctatgtattg acgaaaaaat ctgggatgca
    19381 gaaacaaaga tattgaaaat catcgggtgg ggaatcgcta attcggatcg ccaaccattg
    19441 tcctataagt tatcagccga ccaatcacca ttttttgaag caattcctgt tttacgagaa
    19501 gaagtcaatc aagcaaaaca gctagctgaa ggagcaaaag caggatttga actgcggatc
    19561 ctttgcgaga aggaacgttc attcttagtt gaagcagtgg ctcaaaatgg tcaatcatgg
    19621 atcattgaaa tgtaaataat gattaactta taaagataag gagtaaacga atcgtgcaaa
    19681 aaaaagaaat tgccgtattt atcgatcaaa tcactcgtga acgggccact ggcgatttgc
    19741 ttattgtggg ctgggcaatt gatgaagtga ccaaagaaat ccctacgata aaggtagaaa
    19801 aagaaaatgt gattgctgaa gcaacacatg tcgtaagatt ggatatcaat catttatata
    19861 atcttgatgt taagacccaa agcggtttta aggtacgttt atcagggaaa atgagaggaa
    19921 aagcaatctt agacttccaa acagcaagac atcaaaatgg catagctgtg aaattaaacg
    19981 gtaaatatcc ttatgatgac ggcattgaat cttcatggga aagaaaaaaa agattactga
    20041 aaaaagggat aaattatgca aggactcatg gcgtaaaaaa agcaatccgc cgggtcaaac
    20101 tggaattgaa accaggatcg atcgactatg cagagtggat cagtcgtcat gagaaacctg
    20161 atctgaaaga gcaaaggaaa gaagtacaag gatttgccta ccgcccattg atttccatac
    20221 ttatgcctgt ctataacgtt gaaatcaaat ggctcgaaaa atgcattgat tcggtacttg
    20281 atcaaacgta tgatcactgg gaactatgta tcagtgatga tgcttctact gatccagcta
    20341 tccgaaagtg tctagaatcc tatcaagcaa aagatgatag aattaaagtc gttttccgac
    20401 aagaaaatgg acacatcagc ctggcaacta attctgcatt ggaaatggca gaaggagagt
    20461 ttatagcgct cttagataat gatgacgaat tacctccatt tgccttatat gaagtggcaa
    20521 aagtgctaaa cgtacatcca gaactggatt tgatctacag tgacgaagat aaaatcgatg
    20581 cagatgggaa tcgctttgac ccgcacttca aagcagactg gtctcccgat acattgatgg
    20641 gaaataatta tatctctcac ttaggcgtat atcggacaag cattgttaag gaacttggcg
    20701 gtttccgtaa aggatatgaa ggctctcaag attatgattt ggttcttcgt gtgacagaac
    20761 aaattcctgc agaacacatt taccacattg accgtgtctt gtatcattgg cggacgatcc
    20821 cgggatcaac tgcaagcaat ggagaagcta aaagctacat ctatgattct ggagtgaaag
    20881 cattgacaga tgctctatct agaagaaata tcaagggaag cgtacatcct ggcagaattt
    20941 ctggttttta tgaaatcact tatgatgttt tgcaagaaga cttggtcagt gtgatcattc
    21001 caactaagaa tggctatgaa gatctaaaaa cttgtgtgga ttcgatcatc gaaaaaacgt
    21061 cttatccaaa ttatgaaatc attattgcag ataatggaag tacagatcct aaaatgcaag
    21121 aattatttgc agaatacaag catcagctga aagaccgatt tatcgtcgaa ttaattgaca
    21181 ttccattcaa ttattcacgt atcaacaatc tggcagcaga aaaagcaaac ggcaaatact
    21241 ttttattctt gaataacgat acagaagtga ttgaacctga ctggatgaca gcgatggttt
    21301 cttatgcaca gtttgatcga atcggctgtg taggagcaaa actgttttat ccagatgata
    21361 caacgcagca tgcaggagta ttattaggaa tcggtggtgt tgcagggcat gcattgaata
    21421 actatgatcg aacacattgt ggttatttcg gccgattggt cattgacgtc aattacttag
    21481 cagtcactgc agcttgtatg atggtcaagg cagctgactt caatgctgtt aacgggtttg
    21541 atgaaacatt agaagtagca ttcaacgatg ttgacttgtg cttgaaagtt tatgaactgg
    21601 gtcgttacaa tgtctatgca catcaagcag aattgtacca tttcgaatct aaatcaagag
    21661 gttatgaaga tactccagaa aaacaaagac gttttgctgg tgaaatcaaa aaaatgcaag
    21721 ataaatggcc agcatatatt gcgcatgatc cattttacaa tgataattta acaaaagaag
    21781 gaatcggcga cttttcgttg agaccagatt aaactataat aaaaagctgt tatgttgtga
    21841 ttcgctcgca cataacggct ttttatagtt ttttgtcaaa aaaaggcaga aggtgccgac
    21901 tcaaaaaaat aagtcgaggt tgggacagaa gtgtttaact ccgagaaata agaagaaatt
    21961 cacgaaaatt gcttttcaaa tttttgtgaa tttcggctta tttaagaaga agttgcttct
    22021 gctcccaccg tttattcgtt tttaaagaat gagacaaaag tgtttcttac ttttgtccca
    22081 cgctcttatt catgctcaga gcgccaatag atacaaaatc atagccaaag tttcacgaac
    22141 cctagctgtc aaagaatcga tattttattt taatataggc tattttaaaa taaatggttt
    22201 aaggtattcc tctacaaaag ccactctatc aattatcatg ggtttaaaat aagaagtgat
    22261 ggagataacc agattgttct tagcgtcaat ataaagaaca tttccactat taccaattgc
    22321 tgaatatatt tcgttctcag aatctaatac ccaccataaa tagccatatc tcatattttg
    22381 taagtcttct aaagcactgg ttctaggttt gaacatctcg tttatccaca tgggtggtac
    22441 gatttgtttt cctttataca tccctttatt taggcataat acaccaattt ttgccagatc
    22501 acttgccgat aaacacaaac catatcctgc cgtcccgata tttagtggat cacaaaacca
    22561 gacattggtt ttaggagact tatccattgt aaactgctta tgttcttcag ctgtttcagc
    22621 ataataattg acatggtttg gtatccctat aggatcaaat agatacttat tggcaaaatc
    22681 aacagttgtt agcttacttg tctgatacaa caagccagtt aatatgtgta aacagacagt
    22741 ttgatagttg aattcgccgg ttataccttt tcttcctccc aataaatcta gtgatgtttt
    22801 tgtccaatct tcacttgaac agacttttgt ccatggatcg cctttacatt tgtagggtgc
    22861 tttcattgtt agcaagtgct tgattgtaat agcgtaaata gttttctccc cgcgtttcac
    22921 tttatactct ggaaaataat ctaatacttt atcatcgata cttttgatta atccttgctc
    22981 taaagcaatg ccaatcagca aagatacaat acttttcgtt gctgacatga tatgacaagt
    23041 atcgtctttt ttataaccat tccattcatc tgtataaact tctaccccat ccttatatgc
    23101 gacaatttga catatatttg gttgtcgaaa accaataaaa tcatgcaact cttgtttatt
    23161 cataagatat tacctcactt tcttctataa gcataatgtc attaaaaatc gatttcaatt
    23221 ttttcgattc ttcacgtaat acaggtattc ttatggacta gacagcgctt tgggaagatg
    23281 gattctctga aaaatataaa ggttcacttt atgagtggat aaaaaaagca gcaaatactt
    23341 cgacttcttt aatttaccaa cattagtgaa aatcgattca tctggagatt tgtaatttag
    23401 agtccttgtc ttgattagag gtgtataaag ctttttatta gacattttta aattccatta
    23461 caatttgctt ataaactagg tttttaaagg tgactatggt aagataatag agatattatt
    23521 ttgtgattag gagtgtatat atgaataaaa atggagaatg gagtgctgca cgacggatat
    23581 tcattatatt aatggatgtt attgtataca atgcagcaat atatagtagt ttcttactga
    23641 agtttcgtgg agagatccca ttacgaaatt tagaaacttt ccaacactca gcaattatta
    23701 tttcagtgat ttttattgcg ttgaacattt tgttgggtgc atatgttttt tataatcgaa
    23761 tgatcagtga catcgtgttt gtcacagtca tcggtcaggt attgatgaca ctagggatca
    23821 tggtagtgac ttttgcgggc cgctggtttg cttttccacg tcttgttatc ttactttcat
    23881 ttgttctcgg tacgcttttc ttaagtatct atcgtattct cgtatataaa ctttatttac
    23941 gcgtaagtcg agataaaaag gtcgtcatta ttgggttaga aaaggatgtc gcaccagcaa
    24001 tccaaaattt tggttcaaag aaaaacaaca aacataaagt cgaagcagtc attcttgata
    24061 actattatgc aaacatcaaa aatatgatta aagacatcga tattgtctat cttgcttctc
    24121 atatcgaaga aactgaaaaa atcaaaatct atcaattagt tactaaaaat gaaaaaaaat
    24181 tgtttttgaa tacaacattt gaaaacttga cattgatcaa tccaaatatt atgaatttcg
    24241 aagatgaaag tattattgaa gcatctggat ttagaatcca acctgaatat gaactattca
    24301 aacgtttgtt tgatatcatc gtttcacttg ttttattagt tattgcttca ccatttatgt
    24361 tattcacagc aattttagtc aaagtgacat caccgggacc aatcatctat aaacaagtgc
    24421 ggatcacaaa aaatcaaaag gaattttcaa tctataaatt ccgctcgatg accgccacag
    24481 ccgaagcaaa atctggacca gttttagcta agagcaatga tgcacgagta acgcctgtag
    24541 gtaaatttat tcgagctgtc cgctttgatg aattaccaca aatcttcaat gtgctgaaag
    24601 gcgatatgtc gatcgtagga ccacgtcctg aacgtccttt cttcgtcgat cagttcaatg
    24661 cagaaaaccc ttattactac ttacggcata atgttcgtgc tggtatcact gggtatgcac
    24721 aagtctatgg aaaatatgtc tctgattaca acagtaaatt acgttttgat ttactttata
    24781 tcaaaaaata ttcattgatg cttgatttaa agatcttgct gcaaaccatc aagatcctat
    24841 ttgataaaat gtcctctcaa ggacttgaag aagacgaaaa tgtgatctca ttggcagaaa
    24901 ttgcttttcc gaatgaaaaa atctttcgct agttgggagg cgtaaaaatg aacaatccga
    24961 aattcagcat aatcgtacca gtatacaatg cagaagcaac tattggtcga aagattgata
    25021 ttctaaaaga attggattat gaagagtacg aagtcgtttt agtaaatgat ggatcaacag
    25081 atcaaacaca ggaaatcatt caagaactga ttgaaaatga tgaacgtttt gaattgatta
    25141 ctacgaccaa tcaagggccc ggattagcaa gaaacgaagg aataagacag tcaaaaggag
    25201 aatatctctt attcttcgat gcagatgaca cgccagtaaa aacgatcttg tcagattatg
    25261 atcatttgct agaaaagagt ccaaaagcgg atcttgttgt tagttcgttt gtttttcgta
    25321 caatggacga gggaagaatc gtttccgaaa aagaaaactt agttacagaa tgtcactatc
    25381 taactcacga agagtttata aaagacatgt atcagttaat gaatgaacag ttgatgtatg
    25441 ttgtatggaa caaatgctat cgtagcgata ttctgaaaaa taaccaaatt ctatttaaaa
    25501 cttataatag ttgtgaggat cgaatattta acttacatta ttatgaatac tgtcatcaag
    25561 tgatcatgaa cccaaaagta gaatatattt atgaatttga aggtgggaag gggatcacta
    25621 atcaataccg acctaacaag ttcgaaacat ttaaagaatt ctattcatta gcaaatactg
    25681 taacagacga tattaataaa gacggtatgg cggcgcttct tttaaaaggg acaacttcag
    25741 ttattttttc tatttatagt acctctgcaa gaacttcaaa agagaagaaa gacgaagcaa
    25801 agcagatatt gagtgatcca gtgatccgag aagccaagca aattgctaag acggattctt
    25861 cagcaaaaaa aataacaaag ttgctttaca atatgccagc tccactattt ttatctgctg
    25921 taaaagttgg aagcttcgtt gaagtgaaaa tgccagggtt aatggctgct ttgaagcgag
    25981 tatattagtt aatggaggaa aatataatga aaagaatttt gcattttcag ggacgaatgg
    26041 gtttaggtgg agcagagtct ttcatgatga atttatatcg taaaattgat cgtacaaact
    26101 atcaatttga ttttttgatt tatgaagatt atgcagatgt tcaagactat cattcagaga
    26161 ttgaaagatt aggaggccgt atttttgttg tacctaatcc taagaaaaat atttttaaat
    26221 atttaataga agtgaataag ttactaaaaa aagaatcttt ttctatagtt cacaatcagg
    26281 tttattttgg cgggggaatt aatttatggt tagccaaaaa gaatggaatc agacagagaa
    26341 ttgctcatag ccatgcaact gaagatggaa aatctcaaaa tattgtaatg aatgtattgc
    26401 gtaaattttt aaccaaattg ttgttacaaa atgcaacaga ctaccttgcc gttagtcaag
    26461 aagctggtga aagtctgttt caaaaccatc cctttgagat agttcataat ggtattgatt
    26521 tagagcttta tagtaaaaat tcagaagcta aggttaataa gagaaaagaa ttggatatct
    26581 caatgagtac ttttgttgtg ggaaacattg gacgattaga gaaacaaaaa aatcaatctt
    26641 atttgttaga gattttttta gaaatactaa aaatgaattc tgattcttac ttgattttag
    26701 taggtgaagg gtcacttaga aataaactga aagccaaagc agtagaattg gatatagaga
    26761 aaagagtaaa atttttagga gaaagaaacg atattcccga gttattatct gtgatggatg
    26821 tttttgtaat gccttctctt tatgaaggtc tgccaatggt tggattagaa gcacaagcag
    26881 caaaattaaa attagtctta gcagatacta tttccaaaga tacaaagtta acaaataatg
    26941 tggattttgt atcattagat gaaacaccac aagaatgggc aaaaaaagta ataaaagagc
    27001 cgtatgctaa taaaataaca caagaactaa agagttatga tgtttcgtac actactgaac
    27061 aaatggagag tatatatagt agagatcatt aaaaatgttc aagatatttt aggagtgatt
    27121 atttttgaaa atatgttatt tgatattggc atacaatgat attggcaact taaagagatt
    27181 ggtcaatcga ttgaacgaaa atgcagtttt tattattcat atagataaaa aaactgatat
    27241 agaaccattt attgaagcat ttaaatcata tgataatgtt gaatttttat gtaataaaaa
    27301 ccgtgttaaa atttattggg gtggtttttc cattgtacaa gcagaaatca atttagtaaa
    27361 gagagcatta caaaatgaga aatatttaaa atatgtatta ttatctggtg ctgattatcc
    27421 aatcaaagat aatgagtata tttataatta ttttaaaaag aatagttc
//
LOCUS       DACDAF010000030        26665 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.030, whole genome shotgun sequence.
ACCESSION   DACDAF010000030 DACDAF010000000
VERSION     DACDAF010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.030"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            925..2094
                     /locus_tag="IVZ69_001212"
     CDS             925..2094
                     /locus_tag="IVZ69_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP8183314.1"
                     /translation="MPNFTTEIMETLINKGDLDELFRCHLELAVNSLLQAELTAFLDY
                     EKYDRAGFNSGNSRNGNYSRSFRTEYGELNLVIPRDRNGKFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMSEISELIEKMYGHHYTPQTISNMTKIVSEDIIAFKERSLESRYSVI
                     FMDATHIPLKRQTVSKEAVYIVIGIRLDGTKEVLGFSLAPTESAYVWKEILQDLKDRG
                     LKEVLLVVTDGLSGINDSIHSVYPNAQFQQCCVHISRNIAHKVRVSDRQEICSDFKLV
                     YQASSKEEANNQIRFMIDKWKKQYPRVVKLLMNPAILTFYNFPPSIRRTIYSTNLIEG
                     FNKQLKKYTKRKEQFPNEESLERFLVSQFNNYNQKFLCRVHKGFKEIHDTLESMF"
     gene            2567..3121
                     /locus_tag="IVZ69_001213"
     CDS             2567..3121
                     /locus_tag="IVZ69_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP8183315.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGV"
     gene            complement(3294..3767)
                     /locus_tag="IVZ69_001214"
     CDS             complement(3294..3767)
                     /locus_tag="IVZ69_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP8183316.1"
                     /translation="MRIKPIKDGEQLLFSSEENKPLYLDYVNHNLKIIIKENNLKHIT
                     LHGFRHTHCSLLFESGASVKEVYVRLGHTDIKTTMDDIYTHIAKKQTEETAIRFADFM
                     SSTEEKQGSLQKVKSMVKNEKSRLSLLDSLLNVELSVFFLFRSVCVFETVLILFF"
     gene            3779..4315
                     /locus_tag="IVZ69_001215"
     CDS             3779..4315
                     /locus_tag="IVZ69_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP8183317.1"
                     /translation="MPARIHHISIVNRFIRPTFDFYHNILGLKLLMKTINQDDHTMYH
                     LFFSDNHHRVGTELTFFEVQEGNNQFFGTNTIERTILKVPSEASLHFWEIYFETQGVC
                     HYGIESFSGRPILRFEGPDATRLALVPLREFEDIDDYFPYVTDQIPTEHAILGIDAIQ
                     LRVQYSDATERELLSVGW"
     gene            4355..4726
                     /locus_tag="IVZ69_001216"
     CDS             4355..4726
                     /locus_tag="IVZ69_001216"
                     /inference="COORDINATES: protein motif:HMM:NF013098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP8183318.1"
                     /translation="MTILENQDTQFYQEVQIIQDRENPVAIEGIGSVHHVAFGVENKS
                     DLQRIDKQLQERNFINSGIKDREFFVSLYYRDPNQLLIEIATGEGNLDAKAYENQSPR
                     FEEIPLFLPQYLNFIREQVEQ"
     gene            5010..6281
                     /locus_tag="IVZ69_001217"
     CDS             5010..6281
                     /locus_tag="IVZ69_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HAP8183319.1"
                     /translation="MKLSTQEKQLKNVSLKIPKNKISIFTSVSGSGKSSIVFDTITQE
                     AGRQLNDTYDSFTRLFLPKYSRPEVDEIDNLSTAIVVNQKKIGGSARSTLGTITNINA
                     LFRVLFSCFATPSLGYANAYSFNDPSGMCSVCQGIGKTIAFLIGLLYFSAIDNADFVF
                     SDPFTAEVLSGIEEQAKNHGYFVLVHNVNSAEDVKTIQRNWRFEGFIVVGVRVKEFLE
                     LNNVFDGPVVYIDTHLSKETLRELEQQMNRLFVNTNDYQASTLAVEHLIHYGHEKIAF
                     LSFDYIVGEPSVIQERHQAYIDTLKKYHLTFKSHWIYNNSEFERIYQELAEFTAIVVT
                     GDYLAAKLVKFLKNKNKRVMEQLSIIGFDDITFAELMDPALTTIRLNPGNKGAIAFHQ
                     LIGLAKQEEIKNQVLLLEGELISRDSVHKIK"
     gene            6526..7551
                     /locus_tag="IVZ69_001218"
     CDS             6526..7551
                     /locus_tag="IVZ69_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8183320.1"
                     /translation="MVGIRDVAKRAGVSIATVSRVLNEDPTLSVTDETKRKIAESVNF
                     YHYVKKSPVAKNLTNIALITTVSEVDELEDPYFRTIRRGIQVEAEQSKVNLKKIIRLS
                     ETPLEQDDLLKCQGVLIIGQVLSSVIEEVSAINSNVVVIDDPSIEAEVDAVYTDLTKA
                     TNQHLDRLYKKGHRNIAFIGGGRVRLDSQGNKHVSDDDYRKIAYETWMKQKGLEKYSQ
                     IYLEGWTTLDGMQAADLLLKKHAKDKLPTAIMVGNDPIAVGVYRSLQKNGLHIPEDIS
                     IVSFDNIEVAEFLTPALNTVNVNTEEIGKLAVRMVNERIKEVRNVSIKVIVSNNIIVR
                     ESEKNID"
     gene            7845..8954
                     /locus_tag="IVZ69_001219"
     CDS             7845..8954
                     /locus_tag="IVZ69_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP8183321.1"
                     /translation="MLDEFEKQNPDIKVEMETTPWDQYWVKLEAATTGGNMPDVVTMH
                     SSESYKYMSQNALMGLDDVIKENDIDMGNFTEGIADFYTLEDELYAIPKDASVVGLWY
                     NKELFDNAGVDYPDETWTWETLRQAAIDLTDESKGIYGFASHIGTETGYWPFIYQNGG
                     EVFADDNTKSGLNTPEAQEALAFYRDIALVDHASPTITELQDPDKLSRFQSGRLAMMI
                     EGNWFAPGFLKNDYLVENVASAVLPKGKVNATITNGLGWAASASTKYPEEVKKLMAFL
                     ASEDANKIQAETGASIPALKGFEDEWAASSDTIDLSAFGKMLEYGVPRPYNKDGLRAE
                     QAEVQIINRILSGEVTVEDGTAQIEKEVNAILSGN"
     gene            9037..9933
                     /locus_tag="IVZ69_001220"
                     /pseudo
     CDS             9037..9933
                     /locus_tag="IVZ69_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008378728.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
     gene            9949..10773
                     /locus_tag="IVZ69_001221"
     CDS             9949..10773
                     /locus_tag="IVZ69_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002579255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8183322.1"
                     /translation="MKNKFFSNAPIHIMLILGGIAMALPFIWMILTSGKTLVESTQIP
                     PTIFPEKFQLSNYQQVLDLLPFMAFYINTFLMVVGRVIGSVLFSAMAAYACARLSFPG
                     KNILFSLVLIQMMIPGSIFITPQYLLAQKLGILNTIPALILPGVVSAFGTFLLRQFFL
                     GLPDELEEAAYLEGANIWTIFFKIMLPLAKSGLVALGIFTALFAFKDLMWPLIVNTSI
                     DKMPLAPGLANLQGQYATNFPQLMAGSLLAIWPIVVIFIVFQRKFIEGIATTGSKL"
     gene            10805..12115
                     /locus_tag="IVZ69_001222"
     CDS             10805..12115
                     /locus_tag="IVZ69_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005235059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase/alpha-galactosidase"
                     /protein_id="HAP8183323.1"
                     /translation="MTKITFIGAGSTIFAKNVLGDAMLTPSLQDAHIALYDIDEKRLK
                     ESNLMLKNINKNSNENRADIVSYYDRKEALREADFVINAIQVGGYKPSTVIDFDIPKK
                     YGLRQTIGDTMGIGGIFRTLRTLPVMLDFAKEMEEVCPNAWLLNYTNPMAMLTMGVLK
                     ATSIKTVGLCHSVQVCVPELFEHLGIADQYDLNDFQWKIAGINHMAFLLEITKNGEDF
                     YPTIRQLAAEKPNPHPDSVRFELLKRFGYYITESSEHNAEYHPYFIKSKYPELIDELG
                     IPLDEYLRRCEQQINDWESMREDIVNNGELTHTRSREYASYIMDSITTGTPSVIAGNV
                     LNKGLITNLPTDVCVEVPCLVDKNGVQPTYVGELPTQLAALNRTNINVQELTVEAALT
                     LDKSKIYQAAYLDPHLSSELSLTDIKNLVDDLIEAHGDYLPEYN"
     gene            12263..13522
                     /locus_tag="IVZ69_001223"
     CDS             12263..13522
                     /locus_tag="IVZ69_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP8183324.1"
                     /translation="MKWSKKIILACIALGATISLTACGKNQEDASGKVEIEFFNQKKE
                     MTQTIQEIAKDFEAKNPDIHVKVVDVPNAGEVIKTRMLAGDVPDVINLYPQSIELKEW
                     AKAGYLEDLTEEPYLENIKNGYAQRFAIEDRVYSIPLTANVYGFYYNKTAFEEMGIQA
                     PETWAEFEKIVAEIKDQNKVPFAIAGAEGWTLNGYHQLAIATAAGGEEEANNVWRFSE
                     VNGINAESKEMQKDFNRLDLLREPKALQNNWQGAGYNDTVVTFTKGDALIMPNGSWAM
                     PMIHSQNPDFEVGTFPFPADEAGQSLTIGAGDLALSVSATSQHKEEAKRFVEYMTTPE
                     AMQKYYDVDGAPCAVEGVIENTQDSPLSGLTELAFTDRHLVWLAKDWNSENDFYTLTT
                     NYLHNGNQKAMINALNAFFNPMKADGR"
     gene            13532..14404
                     /locus_tag="IVZ69_001224"
     CDS             13532..14404
                     /locus_tag="IVZ69_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018363968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8183325.1"
                     /translation="MKIKEILNRYWAIIFVAIPIILQMIFFYFPMVQGAFYSLTNWTG
                     LTYNFDFVGLNNYKILFSDPKFIKSIGFTLIVTLCMIAGQIGFGILIARALNANIKGK
                     TFFRAWFFFPAVLSGVVVSLVFKQIFNYGLPKIGSMLGIEFLQTSLLGTTWGAIFAVI
                     FVLLWQGIAMPVIIFLAGFQSIPQEIIEAARMDGANDKQIFWNIEITYLLPSISMVFI
                     MALKGGLTAFDQIFALTGGGPSDATTSLGLLVYNYAFKNNQFGYANAIALVLFILIGI
                     VSLAQLKLSKKFEI"
     gene            14416..15246
                     /locus_tag="IVZ69_001225"
     CDS             14416..15246
                     /locus_tag="IVZ69_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8183326.1"
                     /translation="MKTSKEKNISKYLLLLLGGFMILVPLVSTLFGSFKTTPDIMNNF
                     FRFPNPATLENFRRLLADGIGHYFWNSAIITIIAVVAVTAIIPMAAYSLARKMTRGKA
                     YGLMYLFLILGIFVPFQVIMIPITVMMSKIGLANMWGLILLYLTYAVPQTLFLYVGFI
                     KLNVPISLDEAAEIDGASHFTTYFKIVFPMLKPMHATTIILNALWFWNDFMLPLLILN
                     RDSNMWTLPLFQYNYTGQYFNDYGPSFASYTVGIVTITLVYLAFQRSIIAGMSNGAVK
                     "
     gene            15286..17469
                     /locus_tag="IVZ69_001226"
     CDS             15286..17469
                     /locus_tag="IVZ69_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP8183327.1"
                     /translation="MIIFDNHTQTFHLQNKKISYLLGIEENNYLTHLYFGKKITHYSG
                     GYRYPRTDRSFSPNNANAQDRLLSLDTLPLEFPGYGHGDFREPAHNIKLGNGSRVNDF
                     RYDSYEIQKGKPSLAGLPALYTEDDDEAETLIIQLKDAISGLTLQLFYTIYQNHSVII
                     RSTQLVNNSDKTVEINRLASQSIDFPNRPLELIHLNGTWARERQMTREKIHTGIKVLD
                     SKRGSSSHQQNPFVALVDAKTDEFQGEAYGFNLVYSGNHETVIQKDPFDQTRVIMGIN
                     SFNFGWQLKTGDSFQTPEVVMVYSNEGLNTLSQTYHELYNHRLIRGNYRLKERPTLIN
                     NWEATYFDFNEEKIMNIVDDAKNLGIEMFVLDDGWFGGRENDFTSLGDWVETEGKLAC
                     GLENLAKQVHDNGMKFGIWFEPEMISEDSELFRAHPDWALGIPGRDRSISRNQYVLDF
                     SRQDVRDNIYQQMTAIFDRVPIDYVKWDMNRNMTEVYSVLLDSTMQGEVAHRYMLGLY
                     EFLEKLTTNYPTILFESCSGGGGRFDAGFLYYMPQTWTSDNTDAVARLKIQYGTSLVY
                     PISSMGAHVSAVPNHQTGRETSLTIRGNAAMAGVFGYELDLTQLTSEEKAEIKEQVAF
                     YKKHRQLLQYGTFYRLESPFEGNDTAWMFVSKDQTEAMVFYFRVLAEAAHPLVTLKLA
                     GLAEEATYQMEDVTFAGDELMNLGFYIDSELHGDYATQRFYLKQI"
     gene            17530..18750
                     /locus_tag="IVZ69_001227"
     CDS             17530..18750
                     /locus_tag="IVZ69_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligo-1,6-glucosidase"
                     /protein_id="HAP8183328.1"
                     /translation="MFYLHAFTKKQPDLNWENEEVREEIYAMINYWLDKGLGGFRIDA
                     ILNIKKKLEYGIFESDGEDGLAFIGPWILNQSGIEVWLKEMRERTFKPHNSMTVAEAD
                     VPNERLDEYIGEDGYYSMVFDFSYTDIDVPETGEWFKDSQWTWTDMRTNIFTNQLVTQ
                     DKGWGALYLENHDQPRSINKYIPEEWINDYSKKMLATLFMLLRGTPFIYQGQELGMTN
                     IEMASLEDFDDVATHSQYKRALEYGLAPEQALKAVNKRSRDNSRTPMQWNTQKNARFS
                     TSDNVWLKVNPNYPELNAEAQLTNQQSVFNYYHQLIKLRKNSVYKDVLIYGQFLPVKD
                     KNEHILLYERQLEDKIVLVILNVTATEQEYYVDEQYQQVLINNYEDVLLDQSRKLRLR
                     PFESIVLANYGGQL"
     gene            18747..20207
                     /gene="gtfA"
                     /locus_tag="IVZ69_001228"
     CDS             18747..20207
                     /gene="gtfA"
                     /locus_tag="IVZ69_001228"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HAP8183329.1"
                     /translation="MKIKNEAMLITYADSLGKNMGELKQVLDKHLQGVIGGVHLLPFF
                     PSTGDRGFAPSDYTTVDPALGTWEDVEALGEDYYLMFDFMINHISRESKFFQDFKKNH
                     EQSPYKEMFIRIHEFFPENRPTQEDIDLIYKRKDKAPFQTVEFADGTTEEVWNTFGEE
                     QIDLDVTKEVVKEFIRETIKDMANHGCSLIRLDAFAYAIKKLDTNDFFVEPDIWELLD
                     EVRQEAAKYDVELLPEIHEHYSIQMKIANHDYYIYDFALPMVTLYSLYSGKSERLANW
                     LKMSPMKQFTTLDTHDGIGVVDARDLLTDEELDYTSEELYKVGANVKKVYSSANYNNL
                     DIYQINSTYYSALGDNDRSYLLARAIQVFAPGIPQIYYVGLLAGKNDIELLEATKEGR
                     NINRHYYDLAEIEEEVQRPVIQQLFALLKFRNESAAFDLDGTIEVATPSESEIVITRK
                     NKNGSDSATLTANLDTKEFIIESKDIKIFTSVALKF"
     gene            20284..21390
                     /locus_tag="IVZ69_001229"
                     /pseudo
     CDS             20284..21390
                     /locus_tag="IVZ69_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175341.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            21712..21921
                     /locus_tag="IVZ69_001230"
     CDS             21712..21921
                     /locus_tag="IVZ69_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP8183330.1"
                     /translation="MVVITKNELMKLGYGKYQSERIIRQAKAIMVSKSYTYYENRRLG
                     LVPVESVEEVLGMKIEVEEDFQNHG"
     gene            21914..22063
                     /locus_tag="IVZ69_001231"
     CDS             21914..22063
                     /locus_tag="IVZ69_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HAP8183331.1"
                     /translation="MVNFKKDKNGKYHFTASLGFDKRTGKRVQKNVEGLKQLKKKKSV
                     YRTCF"
     gene            22098..22882
                     /locus_tag="IVZ69_001232"
                     /pseudo
     CDS             22098..22882
                     /locus_tag="IVZ69_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922412.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
     gene            complement(23166..24251)
                     /gene="xerS"
                     /locus_tag="IVZ69_001233"
     CDS             complement(23166..24251)
                     /gene="xerS"
                     /locus_tag="IVZ69_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HAP8183332.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLDNNPMDQVATITDKTTLAARAN
                     AIEKKLFLDKDTQNYLDYIANEYKNTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VININLDDLSLDKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRIQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHSSTNTTTLYTHIDNAATIDALNAL"
     gene            24585..24818
                     /locus_tag="IVZ69_001234"
     CDS             24585..24818
                     /locus_tag="IVZ69_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HAP8183333.1"
                     /translation="MAIKERKFREVGNSVVLTISKEFLKENGLNPGDTVFLDEEKLRA
                     AITKKQALSDEIDLAISQALTEYDTTFRELVDK"
     gene            24815..25222
                     /locus_tag="IVZ69_001235"
     CDS             24815..25222
                     /locus_tag="IVZ69_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP8183334.1"
                     /translation="MSIHYLEAKDIIKMNVIQIKKYSPNEPLGVKDANALEMCVGQLR
                     ASAFGEEVYPSIYEKAAILLIQLIKKHPFHNANKRTAFLATFVFLKINGQLLAIDQKD
                     AVNLAVYIATYDKDFDQLKYEVINTIKTHTQPI"
     gene            complement(25673..26182)
                     /locus_tag="IVZ69_001236"
     CDS             complement(25673..26182)
                     /locus_tag="IVZ69_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183335.1"
                     /translation="MKKVLFAVSLVVNIALAGGLFYTITEMNKLDDQRESLAISNEQY
                     KRKLDEASSTNVDTQEAVESSTIVYSNESSETLTNSERSTAPATETVSQKATITIGSK
                     VFTFIVNGLTIEHDSSRTGKMTELSHEFPVIVTTPSATLNGILVQDNNDNNCYIMVDG
                     QTLYRGTYQ"
     gene            26298..26665
                     /locus_tag="IVZ69_001237"
                     /pseudo
     CDS             26298..26665
                     /locus_tag="IVZ69_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         9169 a         3982 c         4961 g         8553 t
ORIGIN      
        1 attccgaaaa gtgaaaagag caaatataaa atttaatgaa aatatagaac taaataggaa
       61 aacgtagacg taattttcta cgttttcctt ttcatatata ttaaatatta cggaaaatta
      121 tataaactaa tttagtgttt tgtttgtaat tcctaatttt gctccacttt tagataattt
      181 ttaggtctat ttaactcatc agacattcta tgctcatttt tctccaaatt tgtttcaact
      241 ctttcgtact taattttgcg tatttgaaaa ttcttctttt agagtacttt tattacgata
      301 ctagtatgat atatatctat agcaaacagt taaaatcttc ctaaaataag cgaatagcat
      361 tcctaaaacc tataaaattt ttagatgaag cgacaagtgg acaattaata aactacttga
      421 acatgaaatt atggatcacc tttcaaattt agaaaatgga attcttatac ttattgcgca
      481 acatttattg attgcaaaat tatgtgacaa aaaaaactag tagaagaaag aataatggct
      541 tgataataaa gtactaccta ttaaaggtag tactttattt aatttagtat aaattaacat
      601 actactatat tttaggtttc atattatata aattaataat atactaccat ttgttggtag
      661 tataatttaa aggtaataag ttattctttt attactatgt ttgggtttta tagcaaagaa
      721 agtttaataa gagtttggac ctagcaaaca atattaatga ggtcattaaa tcttattatc
      781 tttagtgata taacgaaata tctacacaga caaaatgata gcgtaaaata ttttgtgtaa
      841 atagatattt agggtagaaa aaaagaaagt ccattctgta aaattaaagt taccacaacc
      901 gaaattttat aggaggactt tctcatgccc aattttacta cagaaattat ggaaacacta
      961 atcaataaag gtgatttaga tgaattattt cgatgtcatt tagaattagc tgttaattca
     1021 ttattgcagg ctgaattaac agcttttctt gattatgaaa aatatgatcg tgctgggttc
     1081 aattcaggta attcccgtaa tgggaattat tcacgttcat tcagaacaga gtatggagaa
     1141 ttaaatttgg taattcctag agatagaaat ggtaagtttt ctcaacaaac tttacctgct
     1201 tataaaagaa ccaatgactc tttagaaacc actattattc agctatttca aaaaggaatt
     1261 actatgtctg aaatctctga attgattgaa aaaatgtacg ggcatcacta tacgccacaa
     1321 accatttcaa atatgactaa aatagtttct gaagatatta ttgcctttaa agaaaggtcc
     1381 ttagaatcca gatactctgt catttttatg gatgctactc acattccttt aaaaagacaa
     1441 actgtttcaa aagaagcagt ttatattgta attggcattc gattagatgg aaccaaagag
     1501 gttcttgggt ttagtcttgc tccaactgaa tctgcttatg tttggaaaga gattcttcaa
     1561 gacctaaaag accgtggttt aaaagaggtt ttattagtcg taactgatgg tttaagtggc
     1621 attaacgata gtattcatag tgtttatcca aatgctcaat ttcaacaatg ttgtgtccat
     1681 atatctagaa atatcgctca taaggttcgt gttagtgatc gacaagaaat ctgtagcgat
     1741 ttcaaattag tttatcaagc aagttcaaaa gaagaagcaa ataatcaaat aaggtttatg
     1801 atagataaat ggaaaaagca gtatccacga gtggttaaat tgctcatgaa tcctgctata
     1861 ttaacctttt ataatttccc tccgtcaatc agaagaacta tttattcaac taatttgatt
     1921 gaaggtttta acaaacaatt aaagaaatat accaaaagaa aagagcaatt tcctaatgaa
     1981 gaatctctgg agagatttct agtatctcaa ttcaacaact ataatcaaaa gtttctatgc
     2041 cgagttcata aaggttttaa agaaatacat gatacattag aatcaatgtt ttaacttgat
     2101 caacagaatg ggcttttcca tttacacaaa attattgacg ctcccgacaa aattatgatc
     2161 ttgcgtaaag ttataaaata ttaataaaaa tattttatta atgaaaagct tggtagcacg
     2221 gttattcata tgctaattta tttcacttta tagtaagggg agttcttagt atattgttca
     2281 aacttaaatt tcatataatt taattatgta aattagctat tctaagaact tctacggata
     2341 actgcccgtc taaaatttaa ataagagctt agaatcttca tataagtaag gttaattttt
     2401 ttgtacaaaa aagtcggaat attctgagtt actgaaatga tataaaatca taaactaaat
     2461 cccttgattt tattgacttt caaaagttta tatatataag ttaatgatta tggtaaaata
     2521 tatacataat cattaactca gaatattttt aagaagggaa acaatagtga gctataatgt
     2581 acaaccgtta aggacaaatg aagagataca agattttcag ttttggctaa gaagaacaag
     2641 taatccggaa agagatagtt ttttattttt gtttggaatc aataatgggt tacgtatgtc
     2701 agatattata ggattaaaag ttggagatat acgaggcaaa agtaagccta ttattgttga
     2761 acataaaaca ggtaagcgaa aaccgatttt tatagataat ttgagagaag aaattttatt
     2821 atatactgaa ggtaaagaag aaaatgattg gttatttccg agtcggcaac aaggtcgaca
     2881 tataacaagg gatcgtgtct atcagatata tgcagatata gcagaaaaat taggacgaga
     2941 tgatatagga acacatacat taagaaaaac ttttgggtat cactactaca agaaaactag
     3001 agacattgct accttaatgt ttatttttaa tcatagctcg caagcaatta caaaaaggta
     3061 cattggtata actgaagatg aaataggagc atcacttcgt ggatttaaac taggtgtata
     3121 atttaaaaat ttttataaac agtaaagaca aagattaaaa gctattttta tctagaacga
     3181 ttttatttca taaagttcgc ggaataaaag ctggggttac tggtacttgg tataggttcg
     3241 tgttatataa actaagtaat taaataacat ttttaggttg gaaaaggatg aaattaaaaa
     3301 aagagaatca atacggtctc aaaaacgcaa acgctgcgga ataagaaaaa tactgataac
     3361 tcaacgttta gcagactatc taatagggat agtctgcttt tttcgttttt gaccatactt
     3421 ttgaccttct gcaaacttcc ttgcttttcc tctgtagaac tcatgaaatc tgcaaaacga
     3481 attgccgttt cctctgtctg ctttttcgcg atatgggtgt atatatcatc catagtggtt
     3541 ttaatatctg tatgtccaag tcgaacatac acttctttga cagacgcacc agattcaaag
     3601 agcagactac aatgggtatg acgaaaacca tgaagtgtga tatgttttaa gttattctct
     3661 ttaatgatga ttttcaaatt gtgatttaca tagtctaaat aaaggggctt attttcttct
     3721 gatgaaaaca aaagttgttc accatctttt ataggtttga ttctcatttt tagatattat
     3781 gcccgcacgt attcatcaca tttctattgt gaatcgcttt attcgaccga catttgactt
     3841 ttatcataat atactcggtt taaaattact aatgaaaaca attaatcaag acgatcatac
     3901 catgtatcac ctgttttttt cagataatca ccaccgtgtg ggaactgaac tgactttttt
     3961 tgaagtacaa gaagggaaca accagttttt tggaaccaat acgattgaac gaacgatact
     4021 aaaagttcct tccgaagcat cattgcattt ttgggaaata tattttgaaa cacaaggcgt
     4081 ttgccattat ggaatcgaat cattttctgg acgacctatc ttacgttttg aagggccaga
     4141 tgcaacacga ttagctttag ttcccttacg cgaatttgaa gatattgatg attatttccc
     4201 gtatgtcaca gaccagatcc ctacagagca tgccatttta ggaattgatg ccattcaact
     4261 acgcgtacaa tattccgatg cgactgaacg agagttattg tcggtaggct ggtagcacaa
     4321 agaatacgtc agtttctttt cgggtcatca acgagtgaca atcttagaaa atcaagacac
     4381 tcagttctat caagaagttc agattattca agatcgtgag aatccagttg ccattgaagg
     4441 gattggtagc gtccatcatg ttgcgtttgg cgtagaaaat aaatctgatt tacaacgcat
     4501 cgacaaacaa ttacaagagc gcaattttat aaattcagga ataaaagatc gtgaattttt
     4561 tgtatcactt tattatcgtg acccaaatca attattgatt gaaattgcta caggggaagg
     4621 aaacctagat gcaaaagcgt atgaaaatca aagtccacgc tttgaagaaa ttcctttatt
     4681 tttaccgcag tacttaaatt tcattcgtga acaagtggag caataattag ctaatcaaat
     4741 ccatgacgaa gagtaagagg ttgactcata agtcaaaaaa taaagaaaaa cgcatcaaat
     4801 ccattctaaa gaatgttgat ttgatgcggt tcctattttt ataaactatc attttcgact
     4861 aataaaacta cttatgagtc agcctctctt tttttcttga tttttatacc tctttctagg
     4921 taaactaaac atctgccaaa aataccgtgt ctcattgaaa cattctcaac tatttcaaaa
     4981 taaaggggag taccaaatga acgagtatat tgaaattatc cacgcaagag aaacaactta
     5041 aaaatgtcag tctcaaaatt cccaaaaata aaattagtat ttttaccagc gtatctggtt
     5101 caggaaaatc atcgattgtt tttgatacta ttacccaaga agctggtcgt caactgaatg
     5161 acacctatga tagttttacc cgtttatttt tacctaaata cagtcgtcca gaggttgatg
     5221 agattgataa tctttctacg gcgattgtgg tcaatcaaaa gaagattggt ggcagtgcgc
     5281 gctcaacgtt agggacgatt actaacatca atgcgttatt tcgtgtgttg ttttcatgtt
     5341 ttgcaacacc tagtttagga tatgcaaatg cttattcatt taatgatcct agtggaatgt
     5401 gttctgtctg tcagggaatc ggtaagacga ttgcattttt aataggattg ctttattttt
     5461 cggctattga taatgctgat tttgtatttt ctgatccatt taccgcagaa gttttgtctg
     5521 gaattgagga acaggcaaag aatcatggtt attttgtatt ggtgcataat gttaattcag
     5581 cagaagatgt taaaactatt cagagaaatt ggcgttttga ggggttcatt gttgttggtg
     5641 tacgtgtaaa agaatttttg gaattaaata acgtttttga tggtcctgtt gtttatattg
     5701 atacgcatct ttcaaaagag acattaagag aacttgaaca acaaatgaat cgtttatttg
     5761 taaatacaaa tgattaccaa gctagtacat tggcagtgga acatttgatt cattatggtc
     5821 atgagaaaat agcgtttctt tcttttgact acattgtagg tgaaccaagt gttattcaag
     5881 aacgacatca agcttatatc gatacattaa agaaatatca tttaaccttt aaatcgcatt
     5941 ggatatataa caactctgaa tttgagcgaa tttatcaaga attagctgaa tttactgcaa
     6001 ttgttgttac tggagattat ttagcggcta aattagtaaa atttttaaaa aataagaata
     6061 aacgagtgat ggaacaatta tcgattattg gatttgatga tattactttt gcagaattaa
     6121 tggatcctgc gttgacaaca atacgactaa atccaggtaa caagggggcg attgcttttc
     6181 accaactgat tggactggcc aaacaagaag aaataaaaaa tcaagtacta ctattagagg
     6241 gagaattgat ttctcgagac tctgttcaca aaatcaaata aaaaagctct gtgaaataag
     6301 tatagttaac aataaaatat ccgaacgata gagagaatga actgtgatct agcagttcct
     6361 cgtcgcaaat tcactagaat tagcattatt tactctaaat tgttcggata ttttttcttg
     6421 tttttaatta tgattacagt gcctattttt aacgaaattt gcttattttc aaaatgtatg
     6481 attatatgtt agtaaacact ttcaaatatg aaaagaggag ctattatggt aggaattagg
     6541 gatgttgcaa aacgggcggg tgtgtccatt gcaacagtat cgcgcgtgct aaatgaggat
     6601 ccgacacttt cagtaaccga tgaaaccaaa cgaaagattg cagaatcggt taatttttat
     6661 cattatgtca aaaaaagtcc cgttgcaaaa aatttaacaa atattgcatt aataacgaca
     6721 gtttctgaag tagatgagtt ggaagatccc tattttcgaa cgattcgcag agggattcaa
     6781 gtcgaagcag aacaaagcaa agtcaatttg aagaaaatta ttcgtttgtc agaaacaccg
     6841 ttggagcaag acgatttgct aaaatgtcaa ggtgtgttga ttattgggca ggtgctatct
     6901 tctgtgattg aagaagtatc agcaattaat tcgaatgtcg tagtgattga tgaccctagt
     6961 attgaagctg aagtagatgc agtttatact gatttaacaa aagcaacgaa tcagcattta
     7021 gatcgattgt ataaaaaagg acaccgaaac attgcgttta tcggaggagg acgtgttcgt
     7081 ttagatagcc aaggaaataa acacgtgtca gatgatgatt atcgaaaaat agcctatgag
     7141 acgtggatga aacaaaaagg attagaaaaa tatagtcaaa tttatttaga aggctggacc
     7201 acacttgacg gaatgcaggc agcagattta cttttgaaaa aacatgctaa agataagttg
     7261 ccgactgcta tcatggtagg aaatgatcct attgctgtgg gggtttatcg ttcacttcaa
     7321 aaaaatggtc tacatattcc agaagatatt tcgattgtga gttttgataa tattgaagtt
     7381 gctgaatttt taacacctgc attaaatacg gtgaatgtga atacagaaga aattggaaaa
     7441 ctagcagttc gcatggttaa tgaacgaata aaagaagtta gaaatgtttc gatcaaagtg
     7501 attgtttcta ataatattat tgttagagaa agtgaaaaaa atatcgatta aaaaagtaaa
     7561 catccaaaaa agggtgttta cttttttgtt tactaatatt tttagtaaaa aatctcgaca
     7621 aaacattaag taaacagtta tggtgttgtt aacaaaaaga aaacgcattc aaaacaggag
     7681 gaattaagat gaaacatttc aaaaaaatag ctttaacagg gatagctgtt ttaactggga
     7741 cattactcgc agcatgtggt gggggagata gtaattctaa agacgggcaa gtaactttaa
     7801 gctatgcgag ttgagatact gaccaagctc caggactaag aaaaatgtta gatgaatttg
     7861 aaaaacaaaa tcctgatatc aaagtagaaa tggagacaac gccttgggat caatattggg
     7921 ttaaattaga agctgcaaca acgggaggta atatgccaga tgtagtaacc atgcactcta
     7981 gcgaatccta taaatatatg tcacagaatg ctttgatggg acttgatgat gttatcaaag
     8041 aaaatgatat tgacatggga aactttactg aaggaattgc tgatttctat acgcttgaag
     8101 acgaactata cgcaatccct aaagatgctt ctgtagtggg gctatggtac aacaaagaat
     8161 tatttgataa tgcaggtgtc gattatccag atgaaacatg gacatgggaa acactcagac
     8221 aagctgcaat tgatttaaca gatgaatcaa aaggcatcta tggttttgca tcacatattg
     8281 gaacagagac tggctactgg ccatttattt atcaaaatgg gggagaagta tttgccgatg
     8341 acaatacaaa atcaggtttg aataccccag aagcacaaga agctttagct ttttatcgag
     8401 atattgcact tgttgatcat gcttcaccaa caattacaga attacaagat cctgataagt
     8461 taagtcgttt tcaatcaggt agattagcaa tgatgattga aggaaactgg tttgcaccgg
     8521 gatttttgaa aaatgactat ctagttgaaa atgttgcttc tgccgtgtta cctaagggaa
     8581 aagttaatgc aacaattaca aatggacttg gttgggctgc cagtgcgagt acaaaatacc
     8641 cagaagaagt gaaaaaacta atggcatttt tagctagtga ggacgccaat aaaatccaag
     8701 cggaaacggg ggcatcaatc ccagcactaa aaggctttga agacgagtgg gctgcttctt
     8761 cagatacaat tgatttgagt gcttttggaa aaatgttgga gtatggagtc cctcgtccat
     8821 acaataaaga tggattacga gctgaacaag cagaagttca aattattaac cgtattctgt
     8881 ctggtgaagt aactgttgaa gatggaaccg ctcaaattga aaaagaagtc aatgcgatat
     8941 tgagcggaaa ttaaattagt taattataca atatacaggc gaaaggattc tatttcgtct
     9001 gtatattaat ggatgaatac caaaaagggg gatattatga aaaatcgaat ttttggaaaa
     9061 tatcgtaaag atcaagtgat atggggctat atttttattt ttccaacggc attaggatta
     9121 attttattaa atatatggcc agcaattcaa acagcaattt taagttttca aaaaacggta
     9181 gggttcggtg atactgaatg ggtcggatta agaaattacc aaaaaatgtt tgcagacggt
     9241 gaagtttttc agtctttatt aaacacatta atttatgcag tggtttcgat acctagtatt
     9301 gttgtattat ccttgttggt ggcagtttta atgaatagaa aagttaaagg attgtcgatt
     9361 tatcggacaa tttattttct accagtcgtt gctgcaccat ccgcagtcgc aatgatttgg
     9421 cgctggatgt tcaataatga ttatggactg attaataaca tgttggctaa aataggtctc
     9481 gatggaccag catggttaac ggatccatcg attgcgattt attctattat cattgtagga
     9541 gtttggagtg ctattggtta taacatggtg ttattactag ccggcttata agaaattcct
     9601 aaagattatt atgaagcagc ggaaattgat ggtgctagtc caatccagca gtttttcaac
     9661 attacgttac cattagttac accaacatta ttttttgtag ttgtaacaac agttatcaat
     9721 gctttccaag tatttgatgt tatttttatg atgattactc ctaatagtac cgccatgttt
     9781 aaatcacaat cattagccta tttattctat aaacattcat ttattttaaa tgacaaggga
     9841 tatggttcgg caatcgttat gttcctttta gtgattatat taattattac tgcaattcaa
     9901 atgaagttgc agaaaaagtg ggtaaactat taaggaggct atcaaattat gaaaaataaa
     9961 tttttttcaa atgcgccaat ccatatcatg cttattttag gtggtattgc aatggcatta
    10021 ccttttattt ggatgatttt aacttcaggg aaaacgttgg ttgaatctac ccaaattcca
    10081 cctacaattt tccctgagaa atttcagcta agtaactatc aacaagtact tgatttatta
    10141 ccattcatgg ctttttatat caatacattt ttaatggttg ttggacgagt gattggctcg
    10201 gttttatttt cagcaatggc tgcatatgct tgtgcgcgtc taagttttcc agggaaaaat
    10261 atccttttca gcttagtact tattcaaatg atgattcccg gttccatttt tattactcca
    10321 cagtatttat tagcacaaaa attgggtatt ttaaatacaa ttccagcatt aatattacca
    10381 ggggtagtta gtgcgtttgg tacgttttta ttaagacaat ttttcttagg tttacctgat
    10441 gaattggagg aagcggccta tttagaaggt gccaatattt ggacgatctt tttcaaaatt
    10501 atgttgccgc ttgctaaatc aggattggtt gcacttggaa tattcacagc gttgtttgca
    10561 tttaaagatt taatgtggcc attgattgtc aatacttcaa ttgataagat gcctttagct
    10621 ccgggattag caaacttaca aggacaatat gccacgaact tcccacaatt aatggcaggt
    10681 tcgttattag caatttggcc aatagttgtg atattcatcg ttttccaaag aaaattcatt
    10741 gaaggaattg ctacaacagg tagtaaatta taaaactatt aattagtgat tggagagtaa
    10801 gtacatgaca aaaattacat ttattggtgc aggaagtact atttttgcaa aaaacgtatt
    10861 aggcgatgcg atgttaactc caagtctaca agatgcacat attgcattgt acgatattga
    10921 tgaaaaacga ctaaaagaat caaatttaat gcttaaaaat attaataaaa attcgaatga
    10981 aaatcgtgct gatattgttt cttattatga tcgcaaagaa gcgttaagag aggctgattt
    11041 tgttatcaat gctattcaag tgggtggtta taaaccttca acagtgattg attttgatat
    11101 tcctaaaaaa tatgggttgc gacaaactat tggtgacacc atggggattg gtgggatttt
    11161 tagaacccta cggacactac cagtaatgtt agactttgct aaagaaatgg aagaagtttg
    11221 tccaaatgct tggttattga actatacaaa tccgatggcg atgttaacca tgggtgtttt
    11281 aaaagcgacg agtattaaga ctgttggttt atgtcatagc gttcaagtat gcgtaccaga
    11341 attgtttgag catttaggaa tagccgatca atatgactta aatgactttc aatggaaaat
    11401 tgcaggcatt aatcatatgg cattcttgtt ggaaattaca aaaaatgggg aagatttcta
    11461 tccaacaatt cgtcagttag ctgcagaaaa accaaatcca catccagatt ctgtacgttt
    11521 tgaattgttg aaacgttttg gttactatat tacagaatca agtgaacaca atgcagaata
    11581 ccatccatac tttattaaat caaaataccc agaattgatt gacgaattag ggattccgtt
    11641 ggatgaatac ttacgtcgtt gtgaacaaca aattaatgat tgggaaagca tgcgagagga
    11701 cattgtaaat aatggggagt taacacatac gagaagccgt gaatatgctt catatatcat
    11761 ggattctatt acgacaggaa ctccgtcagt gattgcagga aatgtcttaa ataaaggctt
    11821 aatcacaaac ttaccgacag atgtttgtgt ggaagtacct tgtttagtcg ataaaaatgg
    11881 cgtgcaacca acctatgtcg gtgaattgcc aacacaatta gctgctttaa atcggacgaa
    11941 tatcaatgtt caagaactga cagtagaagc cgctttaaca ctagataaat caaaaattta
    12001 tcaagcagcg tatttagatc cacatctatc atctgaattg tctttaacag atatcaaaaa
    12061 tttagtggat gatttaatcg aagcacatgg ggactattta cctgaatata attaaaaaga
    12121 agctgaaaga gtaaggaatt ttcaattcct tactcttttc ttagttaaat ttagtaaaaa
    12181 tattgacaaa acacttagta aacagttaca ttagtgttaa caaaaagaaa acgcattcaa
    12241 attgtataag gaggagcata aaatgaagtg gtctaaaaaa attattttag cttgtatagc
    12301 actaggagca acgatctctt tgactgcttg tggaaaaaat caggaagatg caagcggtaa
    12361 ggtagaaata gagtttttta atcaaaaaaa agaaatgact caaacgattc aggagattgc
    12421 taaagatttt gaagcaaaaa accctgatat tcatgtaaaa gttgtggatg taccgaatgc
    12481 tggtgaagta attaaaacac gtatgcttgc aggcgatgta ccagatgtca ttaatcttta
    12541 tcctcaaagt atagaattga aagaatgggc gaaagctggt tatttagagg acttaaccga
    12601 agaaccgtat ttagagaata tcaaaaatgg atatgcacaa cgttttgcta ttgaggatcg
    12661 tgtatatagc ataccattaa ccgctaatgt ctatggtttt tactataaca aaactgcttt
    12721 tgaggaaatg gggattcaag caccagaaac ttgggcagaa tttgaaaaaa tagtagctga
    12781 gattaaagat caaaacaaag taccgtttgc gattgcagga gcagaaggct ggactttaaa
    12841 tggttatcac caactagcta tagcgactgc tgctggtggt gaagaggaag cgaacaatgt
    12901 ttggcgtttc tcagaagtta atggaattaa tgctgaaagc aaagaaatgc aaaaagattt
    12961 taatcgatta gatttgttaa gagaaccaaa agctttgcaa aacaactggc aaggtgccgg
    13021 ttataacgat acagtagtta cttttacaaa aggtgatgcg ttgattatgc cgaatggttc
    13081 atgggcaatg ccgatgattc attcacaaaa tccagatttt gaagtaggaa cttttccttt
    13141 tccagcagat gaagcaggtc aaagtctaac gattggcgca ggagacctag ccttatcagt
    13201 ttctgcaact tctcaacata aagaagaagc caaacgtttt gtagaatata tgacaacacc
    13261 tgaagcgatg cagaaatatt atgatgtaga tggtgcaccg tgtgctgttg agggcgttat
    13321 cgagaatact caggattcac cattaagtgg tttaactgaa cttgctttta ctgatcgtca
    13381 tttagtttgg ttagccaaag attggaatag tgaaaatgat ttttatacct taacaacaaa
    13441 ttatttacac aatggcaatc aaaaagccat gattaacgca ttaaatgctt tctttaatcc
    13501 aatgaaagct gacggaaggt aggaaaataa aatgaaaata aaagaaattt taaatcgtta
    13561 ctgggcaatc atttttgtag caattccaat tattttgcag atgatttttt tctactttcc
    13621 aatggttcaa ggtgcttttt acagtttaac taattggact ggtctgactt ataattttga
    13681 ttttgtgggt ttgaacaatt ataagattct tttttctgat ccgaagttta tcaaatcgat
    13741 tggcttcact ttaattgtga cgctttgcat gattgctgga caaattggtt ttggtatttt
    13801 gattgcgcgg gcgttgaacg caaatattaa agggaaaaca ttctttagag catggttctt
    13861 ttttccagcg gtcttatcgg gcgtggttgt ttctttagta tttaaacaaa tttttaacta
    13921 tggtttacca aaaattggta gtatgttagg cattgaattt ttacaaacca gtcttttagg
    13981 aacaacatgg ggagcgattt ttgcagtaat ttttgtttta ctttggcaag gaattgccat
    14041 gccagtcatc attttcttag cgggttttca aagtattcca caagaaatta ttgaagctgc
    14101 tagaatggat ggggcgaatg ataagcaaat tttttggaat attgaaatca cctacttatt
    14161 accaagtatt tcaatggtat ttattatggc attaaaaggt ggcttaacag catttgatca
    14221 aatttttgct ttaactggtg gtggaccaag cgatgccaca acatctttgg ggttacttgt
    14281 ttataattat gcttttaaaa acaatcagtt tggttatgcg aatgctattg ctttagtctt
    14341 atttatctta attgggattg tttcactggc acaattaaaa ttatcgaaaa aatttgaaat
    14401 ctaggaggtt tcccaatgaa aacatcaaaa gaaaaaaata tttctaaata cttgctttta
    14461 ttattagggg gcttcatgat tttagttccc ttagtttcaa cgctattcgg ttcatttaaa
    14521 acaacacccg atattatgaa taatttcttt cgttttccta atccagcgac tttggaaaat
    14581 ttccgaagat tgttagcgga tggaattggt cattactttt ggaattcggc aatcatcaca
    14641 atcattgcag tagttgctgt gacagcaatt attcctatgg ctgcttattc actagcaaga
    14701 aaaatgactc gtgggaaagc atacggattg atgtatttat ttttaatttt aggaattttt
    14761 gttcctttcc aagtaattat gattccgatt accgttatga tgagtaaaat tggtttagca
    14821 aatatgtggg gattaatctt actctatctc acttatgccg taccacagac actattttta
    14881 tatgttggtt ttattaaact aaatgtgcct atcagtctgg atgaggctgc tgaaattgat
    14941 ggggctagtc actttacaac ttatttcaaa attgttttcc caatgttaaa accaatgcat
    15001 gcgacgacta ttattcttaa tgctctatgg ttttggaatg atttcatgct accattatta
    15061 attttaaatc gtgattctaa tatgtggaca ctaccattgt ttcaatataa ttatacggga
    15121 caatatttta acgactatgg tccaagtttt gcttcctata cagtaggaat tgtcacgatt
    15181 acactagttt atcttgcttt ccaaagaagt attatagctg gaatgagcaa tggagcagtg
    15241 aaataaccaa taaattattc tcattataaa ggagttcata aacttatgat tatatttgac
    15301 aatcacacac aaacatttca tttacaaaat aaaaaaatta gctatctatt aggaatcgaa
    15361 gaaaataatt atttaacgca tctttatttt ggaaaaaaga ttacgcacta ttctggtggg
    15421 tatcgctacc cccgaacaga tcgttccttc tcacccaaca atgcaaatgc gcaagatcgt
    15481 ttattatctt tagacacatt accattagaa tttccaggat atggacatgg tgattttaga
    15541 gaaccggcgc ataatattaa attaggaaac ggtagtcgtg taaatgattt tcgttatgat
    15601 agctacgaaa ttcaaaaagg aaagcccagc ttagcgggat tgccagcctt atatacggaa
    15661 gatgatgatg aagctgaaac gctgattatt caattgaaag acgcgattag tggattgact
    15721 ttacagttgt tctacacaat ttatcaaaat cacagtgtaa ttattcgttc tacgcaatta
    15781 gtaaataata gtgataaaac agtggagatt aaccgcttag ctagtcaatc aattgatttt
    15841 ccaaatcgtc cactcgagtt aattcattta aatggtacct gggcaagaga acgtcaaatg
    15901 actagagaaa aaattcatac agggataaaa gtattagata gtaaacgcgg atcaagcagc
    15961 catcaacaaa atccgtttgt tgctttagta gatgccaaaa cagatgaatt tcaaggagag
    16021 gcatatggat ttaatttagt ttatagcggt aatcacgaaa cggtgattca aaaagatcca
    16081 tttgaccaaa cacgggtcat tatgggaatt aattcattta attttggttg gcaactaaaa
    16141 actggcgact catttcaaac gccagaagtc gtgatggttt atagtaatga aggtctgaat
    16201 acgttatcac agacgtatca tgaattgtat aatcaccgtt taattcgtgg aaactatcgt
    16261 ttaaaagaac gtcccacgtt aatcaacaac tgggaagcaa cgtattttga ttttaacgaa
    16321 gaaaaaatca tgaatattgt cgatgatgcg aagaacttgg gcattgaaat gtttgtttta
    16381 gatgatggtt ggtttggcgg tcgtgaaaat gacttcactt cattaggtga ttgggttgaa
    16441 acagaaggca aacttgcttg tggtttggaa aatttagcca agcaagtgca tgataacggg
    16501 atgaaatttg ggatttggtt tgaaccggaa atgatttctg aagatagtga actatttcga
    16561 gcacatccag attgggcatt gggtattcca ggtcgtgacc gctcaattag tcgaaatcaa
    16621 tatgttcttg atttttcaag acaagatgtt cgtgataata tctatcaaca aatgacggcg
    16681 atttttgatc gtgtaccgat tgattatgtg aagtgggata tgaatcgaaa tatgacagaa
    16741 gtctattctg tcttgttgga ctcaacgatg caaggtgaag tggctcatcg ttatatgtta
    16801 gggttatatg aatttttaga aaagttaaca acgaattatc caactatttt atttgaaagt
    16861 tgttcgggtg gaggcggtcg ttttgatgca ggtttcttgt attacatgcc acaaacttgg
    16921 acgagcgaca ataccgatgc cgtggctcgt ctgaaaattc aatatggaac cagcttagtg
    16981 tatccaattt caagtatggg tgcgcatgtt tcagcagtcc caaatcatca aacaggaaga
    17041 gaaacgagtt taactattcg tggcaatgct gcgatggctg gtgtttttgg ttatgagcta
    17101 gatctaacgc aattaacttc tgaagaaaaa gcagaaatta aagaacaagt tgccttttat
    17161 aaaaagcatc gccaactttt gcaatatgga actttttatc gcttggaaag tccgtttgaa
    17221 ggcaatgata ctgcatggat gtttgtctca aaagaccaaa cagaagccat ggtcttttat
    17281 ttccgagtat tagcagaagc tgcgcatcca ttagtcacat tgaaattagc aggattagca
    17341 gaagaagcaa cttatcaaat ggaagatgta acatttgctg gcgatgaatt gatgaatctc
    17401 ggtttttata ttgactcaga actacatggt gattatgcga cacaacgctt ttatttgaaa
    17461 cagatatagt agcttgaatt tacaatataa gtgcaacacc aaaagagact cattccaaac
    17521 gaagaaaata tgttttattt acacgcattt actaaaaagc agcctgattt gaattgggaa
    17581 aatgaagaag tacgtgaaga aatctatgca atgattaact attggttaga taaaggacta
    17641 ggcggattta gaatcgatgc gatattaaac atcaaaaaaa aactagagta tggcatcttt
    17701 gaatctgatg gagaagatgg gttagccttc attgggccct ggattcttaa tcagtcgggc
    17761 attgaagtgt ggttaaaaga aatgagagag cggacattta aaccacataa tagtatgacg
    17821 gtagcagaag ccgatgttcc taatgaacgt ttagatgaat atattggtga agatggctat
    17881 tattcgatgg tttttgattt tagttatacg gatattgatg tacctgaaac tggtgaatgg
    17941 tttaaagata gccaatggac atggacggat atgcgtacca atatttttac gaatcaatta
    18001 gttacgcaag ataaaggttg gggcgcctta tatttagaaa accacgatca accacgttca
    18061 attaataaat atattccaga agaatggatc aatgattata gtaaaaaaat gttggcgacg
    18121 ctttttatgt tactaagagg tacccctttt atttatcaag gacaagaact aggaatgacc
    18181 aacatagaaa tggcatcatt agaagatttt gatgatgtag ctacgcattc tcagtataaa
    18241 cgggcattag aatatggatt ggcaccagag caagcattga aagctgtcaa taaacgaagt
    18301 cgggataatt ctcgcacacc tatgcaatgg aatacgcaaa aaaatgccag attctcaact
    18361 tctgataatg tatggttaaa agtaaatcct aattatccag aactcaatgc agaagctcag
    18421 ttaaccaatc aacagtcggt attcaattat tatcatcaat taattaaatt aagaaaaaat
    18481 agtgtataca aagacgtgct aatctacgga caatttctac cagtgaaaga taaaaatgaa
    18541 catattttgc tttatgaacg ccaattagaa gataaaatcg tattagttat cttaaacgtt
    18601 acagcaacag aacaagaata ttatgtagat gaacagtacc aacaagtatt aatcaataat
    18661 tatgaagatg ttttattaga tcaaagtcga aaattgcgtt tacgaccgtt tgaaagtatt
    18721 gtattagcta attatggagg acaattatga aaattaaaaa cgaagcaatg ctcatcacct
    18781 atgcagatag tttaggaaaa aacatgggcg aattaaaaca agtcttagac aaacatttac
    18841 aaggtgttat tggtggtgta catctgttgc ctttttttcc atcgacaggt gatcgaggct
    18901 ttgcgccgag tgattatacg acagttgatc cagctcttgg aacatgggaa gatgtggaag
    18961 cattaggtga agattattat ttgatgtttg attttatgat taatcacatt tctcgtgaat
    19021 caaaattttt ccaagatttc aaaaaaaacc atgagcagtc accatacaaa gaaatgttta
    19081 tccgtattca tgaatttttc ccagaaaatc gaccaacaca agaagatatt gatttaatct
    19141 acaagcgtaa agacaaagcg ccgtttcaaa cggtagaatt tgcggatggt acgacagaag
    19201 aggtttggaa tacctttggg gaagaacaaa ttgatttaga tgtgaccaaa gaagttgtga
    19261 aagaatttat tcgagaaacc atcaaagata tggcgaacca tggctgttct ttaattcgat
    19321 tagatgcgtt tgcttatgcg attaaaaaat tagataccaa tgatttcttc gtggaaccag
    19381 atatttggga acttttagac gaagtgcgtc aagaagcagc gaaatatgac gtcgaattat
    19441 taccagaaat ccatgagcat tattccattc aaatgaaaat tgccaatcat gattattata
    19501 tctatgactt cgccttgcca atggtcactc tgtattcact ttatagtgga aaatcagaac
    19561 gtttagccaa ttggttgaaa atgagtccga tgaagcagtt tacaacattg gatacgcatg
    19621 atggaattgg tgttgtggac gctcgtgatt tattaacaga tgaagaattg gattacacct
    19681 ctgaggaatt gtataaagtc ggggcgaatg tgaagaaggt ctattcaagt gccaattaca
    19741 ataatttaga tatttatcaa attaacagca cctattatag tgcattaggc gataatgacc
    19801 gtagctatct gttagcacgt gcgattcaag tatttgcgcc agggattcca caaatttatt
    19861 acgttgggtt attagcagga aaaaatgata ttgaactgtt ggaagcaacg aaagaagggc
    19921 gtaatattaa tcgtcattac tatgatttag ccgaaattga agaagaagtg caacggccag
    19981 tgattcaaca attatttgca cttttaaaat ttagaaatga atctgcggcg tttgatttgg
    20041 atggaacgat tgaagtagca acgccatcag aatcagaaat agtgattaca cgtaaaaata
    20101 aaaacggtag tgatagtgca acattaacgg ctaacttgga tacgaaagaa tttatcattg
    20161 agtctaaaga tataaaaatt ttcactagtg ttgcattaaa attttaacct attccataga
    20221 acaaaaaatc ctttatacta gcacttggat gacttatcca agaccaataa aaaggactca
    20281 tacatggata agtataaaac aaatacagca tttaataaat ggttttctgc cataaaatta
    20341 ggaaaacttt ctgtcaactc ccaaaaatgt atttttgatt acaattcgta tcgtaaaaaa
    20401 ctgtcttttg aagctgtgct caagctcttt ctctacgcag ttaatgaaga aaaagaaagt
    20461 ttgcgtgatt tgagtacagc tcttatcgac cgatcgctcc aactagaaac cgatgtgtca
    20521 tcgattagtc atacccaatt gtctcgagca tttaatgcac ttgaacctaa agtgttagaa
    20581 gaaatttttc aacaactgtt agaaaaagtt caacatcaaa tcaaaccaac caagcgaaat
    20641 catctgtatc tgattgattc cagtacgttt tcgcttagtt taaaacgtca taagtgggcg
    20701 actttccgtc aaacaaaatc aggtgtcaag ttacacttaa actattgtta tatggacgat
    20761 actacgatgt atccaactga ttttacctta acaaatgccc atgaacatga tctcaatcaa
    20821 ctaccagtat tggtgaatca accagaggca acttacgtgt ttgatcgtgg gtattaggac
    20881 tttgaaaaga tggatcagat gcattgggat ggctatttct tcgtcactcg gattaaaaaa
    20941 aacaccaaag ttcacgtgat agatactctg gaaacatcgc cagaaacaga aattctacga
    21001 gacgagctgg ttcgtttagg atctaaaacc tatctaaccg ccaatttccg actagtcact
    21061 gttcaagata agaacggacg tgtgtttcaa tttatcacca atcgaatgga cgtctcttca
    21121 aaagaaatct ctgatatgta tcacgctcgt tggcaaatcg aattgttttt caagcacatc
    21181 aaacaacaca tgaccattaa aaccttcttt tctcaaagtg aaaaaggcgt gcagaatcaa
    21241 ttgattttaa cgatgatttc cgctctcctc acgtttctca tcaaattgga gacgaaaacg
    21301 gaaaaatcag tgttccaaat caaacgattc tttcgttatt tactgtttca gccctttgaa
    21361 tgttgtctag aaaaattaat tcccacatga gaaaaaagaa atttggctcg ttacttttgg
    21421 ttttcagttg aataacagat aaaaaatttt ctggaaaaag tcatcctctg cgtcagcaca
    21481 gttttttttg acttattttc agaggaaata gttttcagaa tattctaaaa tgttttatgc
    21541 aacactagtg atatttttta gaattagatt tctaatgtgc attttttgag tattaaggag
    21601 caagtataca aagatttata aagctgatta aatttgaata aaaatatgca ggaacgctac
    21661 tatttttagt agtgttcttt tttatatttg aataaaaaat gtggtggtta aatggtggtt
    21721 ataacaaaaa atgaattaat gaaattaggt tatgggaagt atcagtctga gagaatcata
    21781 cgacaggcaa aagcaattat ggtttcaaaa agctatacct attacgaaaa tagaagatta
    21841 ggactagtac ctgttgaatc tgtagaagaa gttttaggta tgaagataga ggtagaggag
    21901 gattttcaga atcatggtta attttaaaaa agataaaaat gggaaatatc attttactgc
    21961 tagtttggga ttcgacaaac gaacagggaa aagagtacaa aaaaacgtag aggggttaaa
    22021 acagttaaag aagaaaaaaa gcgtataccg aacttgtttc taattatgga aaagaagcag
    22081 aaacttctca aagtactatg ttgtttgagg agttttttta taaattattc ctaccttatt
    22141 atcaagggaa agtagaagaa agaacatata aaaatcggtt atctacaatc aaaaaaactt
    22201 ttcttatttc tttaaaatgg agttaagaga aatacgtcca attgacattc aaaagtggca
    22261 aaataattta ttgagcaaat ataaaaattc ttatgtaaga aacatgtatg ggatttttca
    22321 gatgtcatta gatcgagcag ttgttttggg actacttgaa aaaaatcctg caaaagttat
    22381 tggaaatgtg aagaaaagga aaactacagt tgatttttgg acaaaagaag aatttacaaa
    22441 agttatttca actttttata ttgatgattt gtaccaacat tttggtttta tttgtatgtg
    22501 gttacttttt atgaccgtta tgcgtttggg agaagccact gcattaactt ggaaagatat
    22561 tgattttgaa aataaaaact tgcgtgtgaa taaaacactc tattataaga gagccaaaac
    22621 ctatgagttt gtagaacccg aaacggcttc tagtattcgt acaatcgaac tagacgacaa
    22681 tacaattacc tttttaaaag cttggaagga gcgtcaagtt tcaataggag gcatgtcgtt
    22741 tgtactttct tataatggaa cacctactca gaaatataca atccgtcata ttatgagaag
    22801 acatgcaacg atcgttggtg ttcatataat ccgcatacac ggattaaggc atagtcatgc
    22861 ttctttgctt atatcacaat aaaaagatgc acttcgaatt aaagaaaggt taaaacatgc
    22921 tgatgtacaa acgactttag gaacttatgg tcatttgtat ctaaattcat tgagagagat
    22981 aacaaatgat cccacagatt atatccaaac taatttttct aaaatcaaac cgacacctat
    23041 ttacgataat aaaaaataaa tgataaacaa aagtaggatc acaccaaaag aaacacacta
    23101 gaaaaactat aatacaggct tttctagcgt gttgtttctt atttccgcct atttatacat
    23161 tatactcata aagcatttaa tgcatcgatc gtagccgcat tgtctatatg ggtatataaa
    23221 gttgttgtat tggtacttga atgtcccaat tgttgggcag ttaataccaa tgaatttgtc
    23281 tgttggtaga gtctagtagc taatgtatga cgcagtttgt gagggctgac ttgaattcta
    23341 aagccttttg aatattttgc taccatccgt tcgattgcaa taccggatat acgcttggct
    23401 tctccttggt aaattgctag aaataaagct ttttcgtttt ctgttacttt atatcgttct
    23461 ttccgaatag ctagataatt agctaaatat tccattgcga atgctgctat attgacagca
    23521 tctcttttat ttccttttct agttactacc acattattct tatctaaaga taggtcatct
    23581 aaattaatat ttataacctc ggagagtctc aatccagatc ctaaaatcag tgcattgatc
    23641 gccaggtctc tttctacatc tcgttgataa tagatcaaag ctcgtttact caaagtattt
    23701 ttatattcat tggcaatata atctagataa ttttgtgtat ccttatctag aaataatttt
    23761 ttctcaatgg cattggcacg tgcagctaac gtagttttat ctgtgatggt tgctacttga
    23821 tccataggat tattgtctaa gtatggtttt cctagaggat tattggaact tttcgaaaga
    23881 tatttaaata gaacctttaa tgccgtgata tttctattga tagtagaagt agatagacct
    23941 aagttattat tatctttgag cttagttttt gttgtctctt tttttacatt ttcttttgtg
    24001 cgacgtttca aatgagattt gtacaagttt aggtcatagg cagttaactg tcttatcgag
    24061 gtgatagaag tatcaggaac gatagactca ctcagaagcc attcataaaa gagcttataa
    24121 ttttttagat attctaaagt ggttcgaggt gattgatctt tatcctcacg atcttgaaca
    24181 aaatctttta tataatcggg catatgaagt atgattgtat ctattttttg atatatttct
    24241 gtatttttca tgtcattcat cctttcaata agtaggggag aagagtatct ctataattgg
    24301 actataccaa ttatagaatg ttttgtcaat tggtatgctc taaaatttat taatttgttt
    24361 caaaaaaagc atataaacag gtatacgttt aataatttaa aataaatggt atacataaat
    24421 agggaaggaa atagaaggga gcaatctaaa ttttttgaat tttcttaatt aattatatag
    24481 aaagaacaat ctttctatag agttagacat gagagggact atgcttgatt taaaatcaac
    24541 aagcgtatat actgtatata caaagaaaaa ggagggagaa gactatggca attaaagaaa
    24601 gaaaatttag ggaagtgggg aactcagtag tattaactat ttcaaaggag tttcttaaag
    24661 aaaatgggtt aaatcccgga gatacggttt ttttagatga agaaaaactt cgagcggcaa
    24721 ttacaaaaaa acaagcctta tctgatgaaa ttgatttagc aatatctcaa gcattaactg
    24781 aatatgatac tacttttaga gagcttgtcg ataaatgagt attcattacc tagaagccaa
    24841 agatattata aaaatgaatg taatccaaat aaaaaaatac tctcctaatg aaccccttgg
    24901 tgtaaaggat gcgaatgctt tagaaatgtg tgtagggcaa cttcgagcct cagcttttgg
    24961 tgaagaggtt tatccttcga tttatgaaaa agcagctatc ctacttatac aattgataaa
    25021 gaaacatcct tttcacaatg caaataaacg tactgctttc ttagctactt ttgtcttttt
    25081 gaaaatcaat ggacagcttt tagctattga tcaaaaagat gctgtaaatt tagcggtata
    25141 tattgctacg tatgataagg atttcgatca actaaaatat gaagtgatca acactataaa
    25201 gacacatacg cagcccattt aaggagttac tgtatgtgtc tttatagggt tattagctgc
    25261 tatagcgaaa taattgaagt aaattacaaa tagctataat tcaaatccaa ctatatagaa
    25321 aacgtaaatt ttctatatac ttggatatgc tggaatgttt aagagaataa ttacatttct
    25381 agaaaataca ataaaaatta caggataatt agccatatcc tacctcctct agcagttgct
    25441 caaaagttag cactaagtaa cttctttttt gttgctggta acaatttatc aatactaaaa
    25501 tagcgtttaa gtatctaata aatactaatt ttaaagctct taattattat gaaacacgat
    25561 ataacaatat tgctatatcg tgctattgta atattataca tttgaagaca gcgtattctt
    25621 gttctaatat caggaatttt ttataaatat cagtcatatt aagactcaaa atttattggt
    25681 atgttcctct gtatagagtt tgaccgtcta ccattatata gcaattatta tcattgttgt
    25741 cttgcaccaa tataccgtta agggtagcac taggagtagt aacaatcact ggaaactcat
    25801 gagaaagctc ggtcattttt cctgttctgc tagaatcgtg ttctattgtc aagccattta
    25861 ctataaacgt gaatacttta cttcctattg ttatagtagc tttttgagaa acagtttctg
    25921 tagctggagc tgtgcttctt tccgaatttg ttagggtttc actggattca ttgctataaa
    25981 caattgtaga ggattctacg gcttcttgag tgtccacgtt ggtgctgcta gcttcatcta
    26041 gcttcctttt gtattgttcg ttactgattg ctaagctttc ccgttggtca tcaagcttat
    26101 tcatttctgt aatggtataa aataatcctc ctgctagtgc tatattaaca actaaactaa
    26161 ccgcaaataa tacctttttc attcttcctt ctcttctttc tctttttgta attccttact
    26221 tttggatagg ctacaattaa ctagacagaa aaattaaggt gtgtagacta gaagaaaaca
    26281 taccaggagg aatttttatg tctaagagaa cacgaagaac tttttcacaa gaattcaagc
    26341 aacaaatcgt caatctttac ttagatggaa agccacgtgt agaaatcatt cgagaatatg
    26401 aactaacggc ttcagcattt gacaaatggg taaagcaatc taaaacgagt ggttcattca
    26461 aagaaaaaga taatcttacg cctgaacaaa aagaattgtt agaactacgt aaaagaaacc
    26521 agcaattaga aatggaaaat gatattttaa agcaagcagc gctgatattc ggacgaagag
    26581 acaagtaatc gatgcgaata agcatcttta ccctatatca gcgatgtgca gaatattagg
    26641 tctatcacgt cagtcctatt attat
//
LOCUS       DACDAF010000031        25742 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.031, whole genome shotgun sequence.
ACCESSION   DACDAF010000031 DACDAF010000000
VERSION     DACDAF010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.031"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            136..2196
                     /locus_tag="IVZ69_001238"
     CDS             136..2196
                     /locus_tag="IVZ69_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183336.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            2279..2848
                     /locus_tag="IVZ69_001239"
     CDS             2279..2848
                     /locus_tag="IVZ69_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8183337.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(3023..3829)
                     /locus_tag="IVZ69_001240"
     CDS             complement(3023..3829)
                     /locus_tag="IVZ69_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183338.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            3967..5481
                     /locus_tag="IVZ69_001241"
     CDS             3967..5481
                     /locus_tag="IVZ69_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HAP8183339.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            complement(5884..6867)
                     /locus_tag="IVZ69_001242"
     CDS             complement(5884..6867)
                     /locus_tag="IVZ69_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HAP8183340.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(6872..7519)
                     /locus_tag="IVZ69_001243"
     CDS             complement(6872..7519)
                     /locus_tag="IVZ69_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP8183341.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            complement(7604..8236)
                     /locus_tag="IVZ69_001244"
     CDS             complement(7604..8236)
                     /locus_tag="IVZ69_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP8183342.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            complement(8252..8803)
                     /gene="coaC"
                     /locus_tag="IVZ69_001245"
     CDS             complement(8252..8803)
                     /gene="coaC"
                     /locus_tag="IVZ69_001245"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HAP8183343.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            complement(8800..9537)
                     /locus_tag="IVZ69_001246"
     CDS             complement(8800..9537)
                     /locus_tag="IVZ69_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HAP8183344.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            complement(9534..10523)
                     /locus_tag="IVZ69_001247"
     CDS             complement(9534..10523)
                     /locus_tag="IVZ69_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HAP8183345.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            10781..11323
                     /locus_tag="IVZ69_001248"
     CDS             10781..11323
                     /locus_tag="IVZ69_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8183346.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            11340..12425
                     /locus_tag="IVZ69_001249"
     CDS             11340..12425
                     /locus_tag="IVZ69_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183347.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            12437..13243
                     /locus_tag="IVZ69_001250"
     CDS             12437..13243
                     /locus_tag="IVZ69_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183348.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            13244..14071
                     /locus_tag="IVZ69_001251"
     CDS             13244..14071
                     /locus_tag="IVZ69_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183349.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            14068..15141
                     /locus_tag="IVZ69_001252"
     CDS             14068..15141
                     /locus_tag="IVZ69_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP8183350.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            15569..18265
                     /locus_tag="IVZ69_001253"
     CDS             15569..18265
                     /locus_tag="IVZ69_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8183351.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            18342..18830
                     /locus_tag="IVZ69_001254"
     CDS             18342..18830
                     /locus_tag="IVZ69_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP8183352.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            18842..19336
                     /locus_tag="IVZ69_001255"
     CDS             18842..19336
                     /locus_tag="IVZ69_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8183353.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            19357..20166
                     /locus_tag="IVZ69_001256"
     CDS             19357..20166
                     /locus_tag="IVZ69_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8183354.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFVMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            20163..20984
                     /locus_tag="IVZ69_001257"
     CDS             20163..20984
                     /locus_tag="IVZ69_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP8183355.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLGCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            21035..23134
                     /locus_tag="IVZ69_001258"
     CDS             21035..23134
                     /locus_tag="IVZ69_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HAP8183356.1"
                     /translation="MTINEVIYSPKHPLFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLGNLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPLYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETMNYFAQLFGQLSMSDDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACSGLAEIFEALEQLSLSERYKDIACKLKESICKQMTIDGTF
                     GEQFLEGIGDEEKTTYSVKNYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDPLYQNTMTFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSDMHNH
                     QAFVTRLEELICLADLDGSWWWWPYRLEAKQGEVVRDFGCGKCGWASGLFVSIMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIYIQRRKR"
     gene            23131..24249
                     /locus_tag="IVZ69_001259"
     CDS             23131..24249
                     /locus_tag="IVZ69_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HAP8183357.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            24288..25166
                     /locus_tag="IVZ69_001260"
     CDS             24288..25166
                     /locus_tag="IVZ69_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP8183358.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMLSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            25312..25509
                     /locus_tag="IVZ69_001261"
     CDS             25312..25509
                     /locus_tag="IVZ69_001261"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183359.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
BASE COUNT         8148 a         4464 c         5441 g         7689 t
ORIGIN      
        1 ttcttgaaac aataaaaaat caaaaaaaat actctcctaa tagtccatct tcttttgatt
       61 ttatttatat aatgaaatca tcttatgaaa attactactt catgtttaga caagagtagg
      121 gaggactaag aataaatgtg ttcaaaaaga cgttcaaaac aactaaataa acacgcttgt
      181 cgtttagata aggaacggtc gtgttctgaa aaacactacg ttaagtttat gatgcgcacg
      241 atgctgatca gtttatctgt aggtgtctat atgcatgtac ccgttcaggc aacgacacaa
      301 accatcaagg tcgtacgtac ctctgtttct gagaccactg attcccctat cactattact
      361 catactttca ctgatgcaaa tggaaaacag ctacttcctg cattgacttc ctataataaa
      421 gtcagttatc ctccaacgat aaaccactac tggttaattc ctaacaaaac attatggaca
      481 tcggaaaccg gaagcagtgt gccgctttct atcttttccg atatgactga tcctacaaaa
      541 ggtgatcagt taaaacagat cactgatatt ttgaatcatg ctttgacaga tataaaggac
      601 ggtggaagcg cacaagtttc ttatgtatat gaaaaagatt attcacagtt tgaaagaaag
      661 aaaatcgatg ttctggcagg gacaaaagtt tcgatatctg atctggtaga aaggctgaag
      721 aacgcagatg gaacacaagg agatatgtcc aaagtaattt caaacaatgg gaatatcgtg
      781 gatacgacta atacaggaac atctactatt tccttgtcct attttgatcc aattgcttta
      841 aaaacaatga ctgcatctgc tgtgatccat gttcgtgctg atcaaacagc tatcaaagga
      901 aaagatcttc acttaagaac aggagagagt tacgccccta aagatcttgt tgaatatgta
      961 acaaaaagcg atggaacttc aggaaataaa gaagaaatca aaatgaacgg gacagtagat
     1021 actacaactc cgggagaata tcccgttgta ttaacttata tagactcgaa aacatcaaat
     1081 gtggcagaaa caacagctgt agtttatgta gaagcatctg ctgcttcatc gactgtcatc
     1141 actcatttta tagatagtca aacaaataaa gaacttcaag cagaaacaca tatgagtagt
     1201 gtaaatcgta ttcctgattt gcgcctacct gctgaatttt ctgatcgagt gccaaatata
     1261 gatttatcga cttatgaaca aaatgggaaa gtcacttcta tttctgattg gatgcaagca
     1321 aacggattag acagaaaaag tcactggtcg gagatccttg aagtacttca ctcagaactg
     1381 atgaataata ggaagcaatc aggaggggaa attaccttta cttatgttta tataccagac
     1441 aatcgttcat tagaaggtca tgatcttatt gttcatccaa acgaaaaaat aaacaaagaa
     1501 gagttgatcc aatcagcaac aaattcctta ggtaaacccg taccgttaaa ggatgtatcg
     1561 gttacaatca atgaagtacc attggaggat ggttatttga ccaaacaaac aggtgatttt
     1621 acgattatgt atagttatca tgacccgtat tcactccaag aactccatgc tcagtcacta
     1681 ttacatgttt taccattaaa caaacagata gatcaaaaag aacaaaaaag acaagaagaa
     1741 agcttgtcag aaaaaaaaca acaaatggct catgcagttt ctccaacagg gaaagtaaaa
     1801 caaacaagaa gcctagagtt agcaagaata tctagaaaaa tctcagaatc taataaaacg
     1861 ataaggcaag aagctcattt ggccccacaa gtttctggat tggaaaatga aattttagag
     1921 cctaaaataa aacaacaatc agaaaaagaa tttgttgcta aacagtcgga agatcagaag
     1981 gaatcagatg accagaagga aacgaagaaa aaacgcttgt caactattga ttccaccgat
     2041 gagcatctgc agccgcaagt accacttcct agtccgggaa cacccgcacc tggtggaggt
     2101 attccttctt ctgctttagg agatttcatg cgaggtatgg caggaacatg ggtatacgct
     2161 aatcgaaatg aatttgacgc agatgactgg ttctgattta tatctctatc tgttatagtc
     2221 aaataagtag ctgagtcata tgttatttgg cataatggag acgaggaggg atagaaaaat
     2281 gttagataaa acgttacctt acgcagaaat ctggatgaca agaccacttc aacaaaatgt
     2341 tccaatcacg cctttagcgg aaggttttga atttcgattt tatcaaaaag aagatgaatc
     2401 tgcttgggcg gagattgaga cttccgttgg ggaatttcaa acgacagatg aagcacttga
     2461 gtattttcaa caaaactttg ctccttatcc tgaagaactt gaaagaagga tgttttttgt
     2521 agagacaaaa aaaggagaaa aagtagcaac ctgtaccgct tggcgaaaaa aatcaagaga
     2581 gcaagtgtat ccggtttttc attggttagc agtgaaacca gattaccaag gaaaagggct
     2641 cgcaaaagca ttgactgcca gagtcttgca agaatttcct accctccata cggacggacc
     2701 aatctatctt cacacacaga catggagcca tcaggcgatt gctctttata aaaaaatggg
     2761 ttttactttt attgctgaaa atctagacgg cacacctaat ccagattatg aaaaagttat
     2821 gcaggtttta agtaaattag ataaataacg aaatggtgaa ataagtcctc agtattggga
     2881 taaaaaacga aatagtcatt cctcatatct tacttttttg agttaatact atcggataac
     2941 taatggcatg ccatacattc aaaaaagaag gggcagtgac aaaagtattg tcactgcccc
     3001 ttctcttgtt ttttagcatg ttttatcgtt tgattttttt aggaataaaa ttcttgatga
     3061 acgtaaattt ttggtaatcg tttcgactat agaggtaacc aaatacactg aaaacaactg
     3121 ctccaataaa attaacaaat aaatccttca tagtatccat gattcccacg tctaagtaac
     3181 cattttggat gattgtttta tctgttttac catctgcatt ttgactttca atgattgtcc
     3241 gagtgatatc tggaacatga tagacagtgt ttccgtcttt acttaactcc acactattga
     3301 tttgctggat gatcgtatct ttttgcatat cgaattgcag taatttatct gctgaaaatt
     3361 ccacaaactc ccacataaca ccaactgtca tcgaaaaaca gaaggaaaca actgctagta
     3421 ataaaggagt caagttcatg gtttttgtat ttttattgag caaataaaca agggaaaagc
     3481 cgacaccccc agctaaaaat ccgctgaatg catgtagaaa agtatcccac attgaaaaat
     3541 agccataaaa atcacttaac tctcctaaaa ctgttgaact aaaaataaaa gataacaaaa
     3601 tgatttctag catatttgga atctgtatct ttaatatctt ttccagaaaa taagggattt
     3661 caaataaaat taatgtcagt aataaaagca ttgtatttcc ccagtgttgg ttccagacct
     3721 gatccactag cataataacg acgatgatac gtaataaaat atagattccg tttgtgattc
     3781 tacctgcagt ttttgtactg ttcgtaaaaa aggttttcaa atgattcata aaataactcc
     3841 ttcatgtata tccttaatta tactaagaag cgtgtgttta ccaaagctat atgacttaaa
     3901 gaaaaacaga gttgatattg tgaaaaaaat cacttaatat agtataagga gaaaaggggg
     3961 atacaaatga aaaaattagt tgctggttta ttaacagccg ttgcacttct tgctatgagc
     4021 gcatgcggcg cagatcagaa aaatacagca cagacaagtt ctagtacgaa ggaatctgcc
     4081 gaagtatcat caggcgcttc tgaacaagta tatacagatc caaaagaaat gaaagaatct
     4141 tatgatgtcg tgattattgg agctggtggt gcagggatgg cagcagctat cgaagcaaaa
     4201 gatgctgggt tgaatccagt aattttggaa aagatgcctg ttgccggagg aaacacatct
     4261 aaatcatcaa gcggtatgaa tgcttcagaa acaaaatttc aaaaagaaga aggaatcaaa
     4321 gactcgaatg atgccttcta tgaagaaacg ctaaaaggtg gtggaggaac gaatgataaa
     4381 gaaatgcttc gatactttgt cgatcactct gctgatgcgg tcgattggct agatcaaaac
     4441 ggtatcaaac tggacaactt aacgatcact ggagggatga gtgaaaagag gacacatcgt
     4501 ccgtctgatg gctcggctat tggtggatac ttagtggagg ggttattgaa taacgtccat
     4561 gagcgggaaa tccctatttt tgtcaacgca gatgtgacag acattaagaa aaatggggaa
     4621 acggtcaatg aagtgactgt acatgttcaa ggagaagaac caaaagaggt caccggaaaa
     4681 gcaatcgtag ttaccacagg cggttttggt gccagcaaag aatttattga aaaatatcgt
     4741 cccgatttag ctgattatat tacgacaaat caagaaggat caactggaga tggtatcacc
     4801 atgattgaaa aattaggtgg acaaaccgtt gatatggata aaatacaaat tcatccaact
     4861 gtgcagcagg atgagggggt cttgattggt gaggttgttc gcggagaagg agcaatcttg
     4921 gtcgatcaag aggggaaaag atttgtcaat gaaatggata caagggataa agtatctgca
     4981 gcaattacag cattgcctga aaaatcagct tatttgattt ttgaccaagg cgtgcgtgat
     5041 cgtgccacag ctattgaatt ttatgaccaa aaaggatatg tcacaactgg aaagacaatg
     5101 gaagaattag cagaaaaaat cgatttacca aaagaaacac tagcaaaaac agttgatgga
     5161 tggaatacgg atgttgcgga gaaaaaagat gctcaattca accgtgccac agccatggaa
     5221 catgacttat cgtctccgaa ttattatgcg atcaaaatcg caccaggaat ccattacacg
     5281 atgggcggtg tgaaaatcaa tacgaacact gaagtattag ataaagaaaa ccagccaatt
     5341 agggggttat atgctgctgg tgaagtcaca ggtggcttac atggaaacaa ccggatcggt
     5401 ggaaattcag ttgcggagat cattattttt gggcgacaag cgggcataca agcagctcga
     5461 tttgcttcgg aaaatgaatg aaatagaacg taaataaaaa gaggttgtga aaccagcgtt
     5521 ttgagctaat accgagggtc agctgattga acactgttta gtgaagaggt tgtgaaaaag
     5581 ctgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg tttttaactt
     5641 ggttggactt attaccgcag atgcaagctt ttgaacaccg tttattcgga aaaagagcgt
     5701 gggacaaaag taaagaacac ttttgtctca cgctctaaac acgtataaac ggcggaagca
     5761 gaagaaattc cttcggaaat aagctgaaat tcacaaaaat ttgaaaagca attttcgtga
     5821 atttcttctt atttcttgga gttaaacgct tctgtcccag cctctttttt gatcagcatg
     5881 attttattca gttatcttca aaatgatttt tccgatgttt ttgtttgctt ccatatattc
     5941 atgcgcttgt ttgactgcgc tgaattggaa tgtacggtca atgattggcc gaatcttgcc
     6001 attttctaga aaaggcccag ctttttgcat aaaagtttgt gcgagctctg ctttatactg
     6061 atcacttcta ggtgtcaata atgtaccaag cagttggaca cgtttcccaa tcaatacacc
     6121 aaggtctatc tcaggcacga tggtcccacc tagcatacca atcaagaccc aacgtccatc
     6181 aacggctata gaagctaaat tcttttccca gtaagaagcg ccgatgaaat ccaaaataac
     6241 atcgactccc cgaccttcag tgatttttcg tacctcttct tgaaagtctt gttttttata
     6301 gttgatcaat tcatctgcac caagttcttt acaaaaggcg agtttttctt ctgatcctgc
     6361 agtaacgatg attttcgcgt gagaaagctg tctagctaat tggatcgctg ctgttcccac
     6421 accacttgct cctgcatgga tcaagacagt ttcgccttct tgtaattttc caagccagta
     6481 aagtgtttga taagcagtca aaaaaacttc tgagattcca gcagcagaaa catagtctag
     6541 cgtatcaggg agaaggattg cacgatcggc aggcatcaca gcatattcgg cataaccacc
     6601 tagattgact aatccgtata cttttgtccc aggagtaaaa gtggagatat cacttttatt
     6661 ctcaactacc tctccagcta cttcgactcc caaaataggg tagggaggtt tcaaagagac
     6721 tgattctctt ttcataatat ctgttcgatt gacagctgct gtatggactt tgatcagtaa
     6781 ttcgccttgt tttggtttag gaacaggcac ttcaatttgt tctaatacat ctacagaacc
     6841 aggatgcttg attgaaatgg cacgcatgga tctattcctc ctttgcccat tcttggaatg
     6901 ctgtattcaa ctctttgcta ccttcagaaa gtactagagt cgtacgagaa atatccgttt
     6961 cttccactag agcggcaagt acagcagcaa ctgtagagcg agtgatcgtt tttgatgcct
     7021 tctcattagg cttagttaat tgaatggaag taacttcttc atcgttagtc aatgtgactg
     7081 gttgaagaat gacaaaatct aagttagttc gtttcagcca ttcatctgca taatgtttag
     7141 taatataata atctgtcatg gactcaggcc attttgctgg ttcatctgca taaacagcac
     7201 tgaccatcag atagcgagag acatgcgcat tttcagctgc gatcactgtt ttgattgcgc
     7261 catccaagtc tacttgcaga agattctttc cttgagagcc ggcagcaaaa atcaatacat
     7321 cgatgccttt gaatgcttcg gtcatttttt ccacggacca agttaaatca aaagagacat
     7381 acgaaacatt ctcttttttt actaatgttt gggaagcaac atctctcacc cctgcaaaaa
     7441 tttcatggga acttggagct aaatctttta tcaggtgtcg gccaatttgt ccgtttgcac
     7501 ctacaacaaa aattttcatt tggatcatcc tttcgacgtc aaatctttcc attcaatagt
     7561 aacaccaaaa gagaaaaaaa tcagagatcg gctacgatga ctatcagtta gtaagagaag
     7621 ggtgcttgaa gtatcttaac aagacattgc atactgctgc agtcgcaaga cctgcgacga
     7681 ttccttcagg tataccactt gtaaaaataa ccgctagaat agctgaataa acagcattta
     7741 aatttgttcc gatgactttg gcataatctt gctggaataa aaagtagatc atattcatca
     7801 ctaaaatcgt attggtcaat gaaccggaaa gtccagctaa gaataaagaa acggaatctg
     7861 ctttttgttt cattagtttg cgcagacctt tataaacgaa ataaggaacc accccaatca
     7921 agatgcgagg aataaacgcg atcagcaagg ctttccagct tccatgttct gttccgatga
     7981 ctgggataaa cggagaaaag acaaaagaca aaggtgtttg gataactgtg ctacggatca
     8041 tgctgatcag tccaaatgta ccgccaagaa aagcacctag tcttggtcct aaaacgatcg
     8101 aagcaatgat tacaggaata tgcatggttg ttgcattgat tggaccgata gggataaaac
     8161 ctaaaggcgt aacagctaat aaaatcaaaa tagctaaaaa catcgcagtt aatgtaaagt
     8221 tttttgtatt tttcataagt actccttttt tctaagcatt tctttcatta agagtcagca
     8281 tgacctgttc gatgatcgtc tgaatatcag ctaaggcacc ttttccaaaa tctccacaag
     8341 ctaaaagaga ttctcttggt tcaatttcct gatagccgac agatctcaat gtttccagat
     8401 tacgctgagt gatcgggttt tgatacatat tcgtgttcat ggcaggggca atcaattttg
     8461 gtgttcccac tggaagcgcc attgcgactg ttgaaagaag atcgtctgca atgccgtttg
     8521 ctagcttgcc gataatgttt gctgtagcag gcgcgatgag aaacaagtca gcttgttttg
     8581 ctagttcgat atgattgatt acctgcggat ttgattcttg catgacgtct gtatggactg
     8641 cgcgcttcga cagagattgc aaggttaatg gcgtgataaa atgtgtgctg cttttagaca
     8701 taatcacatc tacctgggca cctaatttga cgaattgact tgtaagatca gcgcttttgt
     8761 aagcagaaat acttccagta acgcctagta agatcttttt cattttgatt cctccagtct
     8821 aattttctca gtaatcaatg cagcaatctc agatttactt tgagcttctt ccactgttcc
     8881 atctttagat aagagatagc cgtggtgtgt ctcgccatgg atttccgtca aatcatttgc
     8941 gaaaataaaa tcagttttgt tatttatcag actatttttt gcgactgcca gaagagattc
     9001 ctttggtaca tctactaata gtttgaaacc aatgattttt gcttttggct gccattcacg
     9061 tagataagaa atgatttttg gtgttttctt caaaacgagc acaagatgct cggtgttaga
     9121 agagatcttt gaaacagtgg tatctgtctg ttcattttcc gcaaaccaat tgtccagttc
     9181 ttcttgcgtt gaagaagtgg gtaggttttt tgccagctgt tcttctgaaa aactaaaagc
     9241 aggagtaaaa tcactgactg ccatactgtg gataatcgca tcgtagtgtt cttttttcgt
     9301 tagttcttct aattgtaaaa ataagtccag tgcagattcg atcgtataaa tcgttatatt
     9361 ggagtgtctt ttcggtttca gtgcttgttt cgtagtcacg taatcgattg tggtatccgg
     9421 attggcagct aaataatcag ctaatgcttg ccctaatcgt cctgtcgaat gatttgtaat
     9481 agcacgtact tgatcgattt tttcagtcgt tcctccagct gtgattagaa tcttcattta
     9541 tggtcaccta catttactag tgttcttcct tggtgtgttc cagcaagtag tttagatgct
     9601 gtttcaggca attgatccag agtaatctct tggacgacca gttcatctgc aatctgcaaa
     9661 tccgccatct gttgccataa agaaagacgt tgatctattg gtacattgac agaatcaatt
     9721 ccaatcaact ggatgtttcg cagaataaaa ggcaagacag tcgcgtttag tttgattccc
     9781 ccagcattgc cacataaagc tactgcaccg ttataagaga tcaatggaag aagactgctt
     9841 agctgctcgc cacctactgt gtcgatgaca tagtcgattt gctgttttcc taaagctttt
     9901 gttgtctctg gcagaaattc atcaggtcgt acgacttgca aagcacctag actttttagc
     9961 catgtgacag actcttcttt tctggaaaag gcaatgattg actggaatcc tagtttatgt
    10021 aacagggcta tcgctgtact gcctacaccg ccagaagcac cagtaacgac aactttttta
    10081 tcggaggtca taccttgacg gattaaagcg ttcacacaca acatagcagt aaaccctgct
    10141 gtaccaagga tcatcgcttg acgcagcgtc atattttttg gtagaggaac taaccagtct
    10201 cctggtactt tttgatattg gctataaccg cctggatggg tgacgccaag cccaaaacca
    10261 gtagcaagta caagatcttc ttttgaaaaa cgtggattgt tactttggac gacagttccg
    10321 gataaatcaa tccctggagt catcggatat gttcgtatca cctgaccaga ctcgctcatt
    10381 gccaatgcat ctttataatt gacatcagaa taggcaattt ttaccaagac ttcattttca
    10441 gccaactcag taaatggcag atcactgatt gctgtatgga aaacaggttc ctttattacc
    10501 tgaaaagatc gaaaagcgtt cattcgtgag acactccttt taaaattttc ttttatcata
    10561 ccataaagcc tactctttta ttcttgttct tccgtaaatt tagacaaaaa ttaggtgaaa
    10621 aataaagaat caaacaacta gaatttattc caaaagataa agaaatattc agcaaaaaaa
    10681 attttacaaa gggttgcctt tttcaataaa tttcgtatac taatacgagt ggtagtaaac
    10741 aggaagttta ctattagaaa acttcgattc ggaggaaatt atggaaattg gtgagaagtt
    10801 aagaaatttg cgcatccaaa agaatttgac acaagaagaa ctaggcgaac gcacagattt
    10861 gtcaaaaggg tatatttccc agttggaacg agatttaagt tcaccatcaa tggaaacatt
    10921 cttttctatt cttgaagtct taggtgtgac tccagaagaa ttttttcatc aagaagcagc
    10981 gaatctgcaa gtggtttatt caaaagaaga tcatacggtt tatttcgatg aagaaaacgg
    11041 gtatgaattg gaatggctcg tggctgattc gaatgaaaaa gaaatggagc ctgtcttgct
    11101 gacttttgaa ggtgcaggag aatataagac gtttgaacct tcattatctg aaacgtttat
    11161 ttttgtatta gaaggggaat tagagttaag cttaggagag acggtctatg tggcaaaagc
    11221 aggacagtcg atctattatc aagcgacaaa acaacatcaa ttaaggaatc atctcaaaaa
    11281 acgaacaaaa gtattgattg ttgcaacgca atcatatttg taatataggg ggtaaaaacg
    11341 tggggaaacc aatcatttca tttgatcaag tagtgaaacg ctatgatgat gaaacagtat
    11401 taaaaaaagt aagttttgag atcgaacaag gaaaatttta tacactgctt ggtccttccg
    11461 gctgtggtaa aacaacgatc ctacgtatta tagctggatt caccgaagct acagaagggg
    11521 acatctattt tgaagggaaa cggttgaatg atttgccagc taataagcga caagtaaata
    11581 cagtcttcca agattatgca ctttttcctc atatgaatgt ttttgataac gttgcttttg
    11641 gattgaagat caagaaaatg tccaaatcag atatcgaaaa gaaggtaaaa gatgctttgc
    11701 gtatggtcca gcttcctgga tacgaaaaac gggagattag tgaaatgtct ggtggtcaaa
    11761 gacagcgtgt agcgattgca cgagcaattg taaatgaacc gaaagtattg ctattagatg
    11821 aaccgttatc ggcgcttgat ttgaaactac gtacagatat gcagtatgaa ctgcgggatc
    11881 tgcaacaacg attaggaatc acgtttattt ttgttactca tgaccaagaa gaagcgttgg
    11941 caatgagtga tgagattttt gtcatgaata aagggaaaat cgtccaaagt ggtacacccg
    12001 tagatattta tgatgagcca atcaatcatt tcgttgctga ttttgttggg gagagcaata
    12061 tcgtggacgg tgtaatgatc gaagataatc tagttgagtt tgttggtaag caatttgaat
    12121 gtgtcgatgg cgggatgcgt ctaaatgaac cagttgaagt tgttttacgc ccagaggatt
    12181 tgacgatcac gacaccagat aaaggaaaac tagtcgtaac ggtcgatact cagctgtttc
    12241 gtggtgtcca ttatgaaatc atctgttatg atgaacagca aaatgaatgg atggtccatt
    12301 caacgaaaaa agctaaagaa ggaagcaaag taggattggc ctttgagcca gaagatatcc
    12361 atgtcatgcg tttcaacgag tctgaagaag aattcgatgc acgtcttgac agctacgaag
    12421 aatagggggg acaagaatga aaacaatgcg caggatctat tccgtccctt atattttgtg
    12481 gctcggttta ttcgtgatcg cgcctgtatt aatgatcatt tatcaatctt tttttgatat
    12541 gaatgggcaa ttcacgctga ataattatct atcttatttt acgtcgggga catcgctttc
    12601 tatgacgatc aattctgtat ggtatgcatt tttgatcacg tttttcacgc tgatcatcag
    12661 ttacccgact gcttattttt taacaaaact gaagcacaag caattatggc tgatgctgat
    12721 tattttgcct acatgggtga atctgctgct taaagcttac gcatttattg ggattttcag
    12781 tgtgcacggc agcgtgaatc atttctttga ttttatcggg atcgggccga aacagatatt
    12841 attcacagac ttcagttttc tgttcgtggc aacgtatatc gagattccat ttatgattat
    12901 gccaattttc aatgcattgg aagagatgaa tccttctttg atcagtgcta gtagagattt
    12961 aggcgcgaat agctttgaga ccttccgacg agtgattttt ccgttatcat taaatggtgt
    13021 gaaaagtggt gtccaagcag tatttattcc ttctctttct ttattcatgc tgactcgtct
    13081 gattggcgga aatcgggtga tcactttagg aacggctatc gaacagcatt tcttggttac
    13141 acaaaactgg gggatgggtt ctacaatcgg tgtgatttta atcattgcta tgttcatcgt
    13201 gatgctcctg acaggcgaga agaaaaaagg aggtcgctca taaatgaaaa aatttaaatg
    13261 gtcgtatctt tatttaggga tcgtcttttt attcttatat gcaccgatct tctatctgat
    13321 tttttattcc ttcaatgaag gaggaacgat gaacagcttt acaggattta cttgggaaaa
    13381 ttatgaagct gtttttgaag atacacgttt gatcattatc gtattgaata cgttcatgct
    13441 ggctttctta tctgcattga tcgccacgat catcgggaca tttggggcta tgggaatcta
    13501 ttacacgaaa aaacgacgtg cacggacagc gttgttgagc atgaataaca tcttattagt
    13561 ctctcctgat gttattatcg gtgctagttt cttgattttc tttacactac taggattcgg
    13621 attaggtttt cagagtgtat tgctttccca tattgctttc agcattccaa tcgtcgtctt
    13681 gatggtcttg ccaaaattgc aggaaatgaa cgattcaatg gtcgatgcgg ctagagacct
    13741 tggtgctaat aatttccaag tagtcaaaaa tatcattttg ccttatcttt ctccaggaat
    13801 catagctgga tattttatgg catttaccta ttctcttgat gattttgcgg ttacattttt
    13861 cgtcacagga aatggcttta cgacgctctc agtagagatc tattctcgtg caagacaagg
    13921 aatcagttta gaaatcaatg cgctaagtgc gttagttttc ttgttctcca tgatattggt
    13981 cattggatac tactttatta gtaaagaaaa ccgtccaaaa cggctgaaga aaaacagaag
    14041 agtacgcgag ggggtggcac ggctgcgatg aaaaaattac aatctctgtt tttaggtatt
    14101 ctcatcatta ttgcggtgct gctgcttggt gttcgtcaac ttgaaaaaac aagtggcatg
    14161 agtggagcaa aggtacttac catctataac tggggagatt atatcgatcc tagtttgatc
    14221 acgaaatttg aaaaagaata tggatacaaa gtgaattatg aaacatttga ttctaatgaa
    14281 gcgatgttca caaaaatcca gcaaggtggg acaaactacg acatcgctat accaagtgaa
    14341 tatatgatcc aaaaaatgat caaagaaaaa ctagtacttc cattagatca ttcgaagatc
    14401 aaaggattaa ataatattga tccacgattt ttagacttgg attttgatcc agataatcag
    14461 tattcgattc catatttttg gggaacttta gggatcgtat ataacgataa attctttgat
    14521 gcaaatcaaa ttaagcattg ggatgatttg tggaagccgg aattaaaaga cagtttgatg
    14581 ctgattgacg gtgcacgaga agttatgggg ctttctttga atagtttagg ctattctttg
    14641 aatagtaaga atatggcaca gctgacagaa gcagcaaata aattgaatca tttaacacca
    14701 aatgtcaaag caatcgtggc agatgagatc aaaatgtata tgatcaatga agaagcctcc
    14761 gtggcagtga cattttctgg cgaagctgcc gatatgatgt gggaaaatga acatttacat
    14821 tatgtgatcc caccagaagg atccaatctt tggtttgata atatcgttat gccaaaaacc
    14881 gtgaaaaata aagaaggtgc ctatgatttc atcaacttta tgctagaacc ggaaaatgcg
    14941 gcacaaaatg cagagtatat tggttattct acaccaaatg aagaagcaaa agcgttattg
    15001 ccaaaagaca tttcgtcgga cgaacaattc tatccatctg atgacacgat ctcccatctt
    15061 gaagtctaca aagatctagg atcgaaatac ctaggcatct ataatgacct attcttagaa
    15121 ttcaagatgt ataggagata atggcaaaac tcagtaagaa tggggactta tcaacgttct
    15181 aaagagctaa aaatcgtcct ttttctatct gagttttcca atcttctacc aaaagcggat
    15241 gaaacgccgc tttttttgtg ttattttatt ttttctacca cgtttttcta ccagagaaaa
    15301 gtggacaaaa ccattgtaaa atagggcccg agacgggcta gtaaatctaa gattgaaaaa
    15361 gttacagaag gataaagtaa ttggaaacta tgcaaatata cttaaccctt ctgtaatcta
    15421 ttaataaaac taatatatga atccagttca atatttgtag ctatgaaaaa acataaaaat
    15481 catattagat aaaaactaaa ttggtagata aattattttg tcagatatct gaggcaaata
    15541 ttcgactatt tgtgtttcaa agtaaaaatt ggaatacaaa tatagaatag acatattgca
    15601 gccgatagtt tattatgctt ttagacacat taaactggag gaaaaaatga aaaagagcgc
    15661 taaagatcga gtttttgatg agctgatacg actaacaggg aatatgtctt ctgtcactgc
    15721 cgagaaaatt tcgaagaatc taggtatctc tcgtcagaat gccagccatt atttgacgag
    15781 attagtggaa gataaaaagg tcgagaaatt accgggaaag cctgttttgt ggaagccttt
    15841 agatgaatat gcggttgtag ataatacgga gcaaataaac gaagcctttc attctgtagt
    15901 tggtcatgac ggaagtctga gagaggtcat tcaaaaatgt atagccgctg tcaaatatcc
    15961 gcctaacgga ctcagtgtat taataaatgg agccacgggt gttggaaaaa gttttttagc
    16021 cacaaaaatt tttgaatacg ctatccatga gcaaattatt gaaaaagatg caccatttgc
    16081 tatcttaaac tgtgccgatt atgcggacaa tcccgaactg ctttcggcaa cactgtttgg
    16141 atacaagaag ggggccttta cgggggctga aaaggatacc gatggtttat tggcaacggc
    16201 caacaacggc tatctttttc tcgatgaggt ccatcgccta tcgaaagaaa atcaagaaaa
    16261 gctctttcta tttattgata ctggaaacta tcgtccagtc ggtgaaaatg taaattggca
    16321 ttctgctaag gttcgtttta ttttcgccac gacggaaaaa ggtgaaaatt atttattaga
    16381 cacctttgat cggcgtattc aaattagtgt tatgttgcca acttttgaag atcgccccat
    16441 tcgagaacga ttagagctga ttcaattatt ttttcaaaat gaagcggatg ttttacaaaa
    16501 agatattatt gtttcaagag aagccttgtc tttaatgtta tctcatccct ttagtgggaa
    16561 tattggtaag ctgaagaata tcattaaaat cagttgtgcg gatgtgtata gtcgaacaca
    16621 agaagaacca ttaacgattg ggaaaaatga gatcttgatt cagttaaata tgctggaatc
    16681 cgaagtagaa agcttgccga ttgctagttt attgataaag aaaaatcaaa agataaaaac
    16741 ggatcgaatc aaaccgtttg attatgattc gattttggaa aaaattactc agctgataaa
    16801 tgaaggtaat ttcaatgaaa atttttcttc gataaagaat gaagtacagc atttggtgca
    16861 tcacattgat aaggattctt ttttatcaat gagtagaaaa ttgatgattc agatgtttag
    16921 aaaggtctgg gtatccgttt taggaaaaac gtacggattg acgacgagtg gacctgttgc
    16981 agaaattatt agcagatcct atgtcatttc cccaagctat aagacagact taaccgggat
    17041 aaatcgtaca ttagctgcaa atctacctcg gacgacttac ttatgtaatc agttcttgga
    17101 gcatttacca ccgctctcag aaaaggacga gaactttcta agactgctta ttgtcgtgac
    17161 tttatctgat tatgtagatg aatccatcga gctgaagggc ctgttgcttg ctcacggaga
    17221 tagtacggct agcagcattc aagcagtagt gaatcaatta tgcggcaatt atgtttttga
    17281 agcgttggat atgccagtag agagtaatgt gtcagagatt gtcgaatcga caaggaattt
    17341 cgtgaaacgg caagtgaata cagatagtct agtgctgatc gtagatatgg gctctttaaa
    17401 tcaaatttac acacagatca agaacgattt aaaaggggag ttacttcttc tgaataattt
    17461 gacgacttcc attgcacttg atattggctt gaagatgacg atgaatgcgc catttaaaca
    17521 gattgcggag gatgcagcag acaagtattc aatcaatgtt caatactttg aaggcttttc
    17581 tcaaagtagc aacattatca tttcctgtat gtcgggtttg gggatttcgg acaaattgaa
    17641 agatgttttt cgtcatcatt tatcggatga atccatcgaa gttttcacga aggactacag
    17701 agaactacgt gaattaatcg accaaaatga tgaaacttat tttgacaaga caaaattggt
    17761 catcacgact tcggatcttc cacgttcctt ttcaattcct aatattaatg tttatgacat
    17821 cttagacggt gatggagcag ccaatttgga gcatattttg agtcctgaaa tgaagccggc
    17881 agaatttaac cgcttgattc aggagctagt aaaattcttt tcgttggaag gaattgcgga
    17941 ccgtttgaac tttctgaacc caacgatcgt gatgagtgaa gtggaaacag tcatttctaa
    18001 atatgaaaat tactatcatt tcactttaaa tggccgtgta aaactaaatc tctatatgca
    18061 tacggcattg atgatggaac gtttattctt ggctcggaca gaaaaatctg aagaaccgaa
    18121 ttatgatttg aaaccagatg aagatgaatt ttattatgtt tctagaagta tttttcaatc
    18181 aatggagatg aaatataatt ttaaagtcaa tgcttatgag ctttcgctgc tctatgaatt
    18241 attaggaccg tatattcaaa aataaagtgt ctaaaaaagt gtctaatctg ttttttttag
    18301 gttagacact ttttttaatg tgaattaacg tgattaaacc aatgttttta aaagttggca
    18361 caggaattgc ttatataaaa gtgaacagaa agaaaggaat taaccatatg aagaaaattc
    18421 taatagcgac tcacggtcac ttagcttcag gctttcttag cagtattcaa ttactgacgg
    18481 ggaaggttca agagattacg gtgattaatg cttatgtgga tgagtgtgat tttgaacagg
    18541 agttgaatgt atttgtaaac caggtgaacg agcaggatca gatttttgtt tttaccgatt
    18601 tatttggcgg aagtgtcaat cagaagatta ccaaaacctt tttggagaaa gagattgctg
    18661 taactatttt gtctggcttt aatctgccaa ttctgctcga aatagtattg gcaaccaagg
    18721 aattaacaaa ggaggatatt caggaactgg taaataaatg ccaacaggaa ttaaagatga
    18781 ccattcttga tgaggtacat gtagtaaatg aagaggaaga ttttttttag gaggaagaaa
    18841 aatgattaaa gcagtgcgaa ttgatgaacg attaattcat ggacaagtag cgatgacttg
    18901 gacaaagagt ctaaatttaa ccgggttagt agtagcaagc gatgaggcgg ctaccaacga
    18961 tattcaaaag atgacattga agatggctgc accatcgaat gtcaaagtca ttattaaaac
    19021 agttgatgac gcgattcatt tgttaaaaga tccgcgggcg aaggacatgc gcttgatggt
    19081 tttagtccct aatgtcaaag atgcggtaaa agttgcgaaa gctttcccaa cggaaatcga
    19141 attaatgaac gtggggaatg ctgggaaaat gacaccgcca tcggaagata agaaaacctt
    19201 atcaaaggaa gtgatgttaa cgacgtcaga aattcaagac ttaaaagaat tagttgaact
    19261 ttatccagat accgtttttc agcctacacc ggcgatggaa aaacgttcag ctatctctat
    19321 tttgagtgat ttttagaaaa aggaaggaga aaaattatgt atgatgcatt tgtagtcgct
    19381 ttggccgttt ttattggagt tgctggacat gaaatgttcg ggatgtccat gctgagtcgt
    19441 ccgattgttg ttgctccgtt agcaggagcg ttgatggggg atttgcagac ggggttgatt
    19501 gtcggggcgt cactagaagc catttttatg ggtgtcgtca atatcggaat ctctagtacg
    19561 gcggagcctt ctttggctgc tgggttggct acagcgttcg caatcaaaat gggaggaaac
    19621 gtggatgcga ttattcccat tgtctttcca ctagcagtat taggattaca gttaatgaat
    19681 atgatttttt cttttgtatg tggaccgatg gctgctaaat ttttcaaatt tgcaaaatct
    19741 ggtgatcaaa aaggaatcat caatctgcac ttcgttatgt ggtttgtcca ctatgcgctt
    19801 tatgctctta ttccattctt tgccgtttta tttggagcag atgttgtcaa aagcgtcttg
    19861 gataatattc cagaggtcat catgaacgga ttaacagtcg ctggaaatct gctgccggca
    19921 gttgggatgg cgatgctgtt acggatgctt tggagtaaaa atattgctgt gtggtttttc
    19981 tttggggccg ttgttatggc gtatctcgag ttaccattga ttgcaattgc cgcagttgga
    20041 acgattattg caattgttat agcccaaaga gatctacaac taaaaaatat atctgttcat
    20101 gcagttcaaa gcgatgctgc tgtaaatgca acgcttgacc aagaagagga ggatttcttt
    20161 caatgaaatt agctgatgga atttctaaag atgagaaaaa attggttcgg aagatgtttt
    20221 ggcgctcgat gaccatgtat gcttcggtga atccggtgac gatgggcggc ggtggtttcg
    20281 cctattctat gatgcccttc attaatcatt tctacaaaag tgaagaagat cgagctgcgg
    20341 cgctggaacg tcatacacag tatttttcga cgaccattcc ttgcgcgtcc tttgtcatgg
    20401 ggattgcggc atcgatggag aaggaaaatt ctgaaaaagc tggttttgac gtggaaagta
    20461 tcaacgcgat caaaacgagt ttgatgggac cattggctgg aattggcgat tcattgttct
    20521 ggggagtttg gcgtgtcgtt accgcgggac tagcgatcaa cttagccaat gccggaaata
    20581 ttttggcacc aattatcttt ttagttatgt tcaatatacc taattatttg atgcgatact
    20641 atggcggcgt tttaggctat tcattaggct ctaaatatat tgaaaagctg tatgcgaacg
    20701 ggttaattga aattctgaca aaagctgcta gtatcttggg tctgatcatg gtaggcgcaa
    20761 tgacgatcag tatggtcaaa ttcaataccg ttttgagctt ttcaatgaag ggcgaagaac
    20821 taatgaatgt ccaagaaatc ctcgatagta tttttaaagg aattgtaccg ttattggtaa
    20881 cattgggctg tttcaaatta ctagataaaa aagtcggcgt catcaaaatt atttttggaa
    20941 tggtcgtctt gggaatttta ttgtcattac ttggaatcgc atagtaggaa gctgcagcta
    21001 ctaggctgca gtttttttag caaggaggga aaagatgact attaatgaag taatttattc
    21061 acccaaacac ccattattta atgctgagtt aaacgacgga aatgtgacta cttcaaacga
    21121 atacagctac tatcggaata ttcctgatgt aaagggattg acctttgatg taagtaatca
    21181 aaagacatta ggaaaccttg atgtttgcgg gacgattcaa acgttgacct tttatcgaga
    21241 aaatttacta actgaggaaa aaccaggtgt ttgggtcaat aaacagcttt ctcaaaccaa
    21301 ttcgttatcc ttaaaggttg aagtaaacgg gattgtctac catttgtcag aatcggatca
    21361 tcgtattgaa gtcgatgtga ttcaagactg tttgcctaga tatattcatc attattcgac
    21421 gtttaaggtc attgtagtat cctttgctcc aatactggct aataagcgtt taagtatgct
    21481 tgttcaacag gtttacattg tgaatgaaac acacgaaagc cttcaagttt cagtgaaaga
    21541 tgtgcctttg taccaagaga agtattcgga tcagcaaaat gtgttgattt ctcaaaaagg
    21601 aaataaggac acgatcgcac aacaggaagt ggcaagcttc gccattgctt ttgtggaccc
    21661 aaatgctttt gaagaagtaa tgacttttca ggaatctgat atcgaaaaat ggctgaagga
    21721 aacaatgaac tattttgctc agctatttgg gcagctgtca atgtcagacg atagagttgt
    21781 ccatctctat cgtcgtgcac tttatcaaag cttttctagt ttcggtatga atcgacaggg
    21841 acaggtcgtc ggcagcaatt ggggcagcta tcctgctact aatcgaattt ggaataagga
    21901 tatgtattac gcatcattgc cattcaccat gtttgaaccg gagttatgtc aaaaaacggt
    21961 tctatggttt gatcaatatg gcgttaagtt tcctggttca aaatttacag gaggtatcaa
    22021 tcattctctg agtaattcgt tatccagtgc gttactggct agtctttatt ttgaacatac
    22081 tggggataca aaattctttg agcggtgtcc gcaggttcta ctgaatgctt caagaattat
    22141 tgaggacata ttagctcaac gtcggtcagg ggaaccaatg ctttttccat ctgtttggtt
    22201 atcagacgcc tttgcacttg gaaagtatca taccggcagc aatctttgtc tttggaaggc
    22261 ctgtagtgga cttgcagaaa tttttgaagc cctagaacaa ctgagtctta gcgagcgata
    22321 caaagacatc gcctgtaaac taaaggaatc aatttgtaaa caaatgacca tagatggtac
    22381 ttttggggag caatttttgg aggggatcgg tgatgaggag aaaacaacct attcagtgaa
    22441 gaactatcaa aaaccgattc ttgagcaagg gttaatcttt ttaagtgatg tgattgtgga
    22501 tgggaaaatc aatttattga tgcatgatgg agaagaatca gacactacgt tgatgccttt
    22561 ttatcaattt ttagataata aagatccttt atatcagaac accatgacct tttctgctag
    22621 ttctttcaat ccaacttata gcgaggaaat caaaggcatc acttggggat tagaatccgg
    22681 cgccactttt cctggcttta tcactgtttt aatgagtgac atgcacaacc atcaagcctt
    22741 cgtaacccga ttagaggagc tgatttgttt ggcagattta gacggttcat ggtggtggtg
    22801 gccgtatcgt ttagaggcta aacaaggaga agttgtgcga gactttggct gcggcaaatg
    22861 cggctgggca tcgggccttt ttgtcagtat aatgatcagt caatatttcg gattgaaatt
    22921 caaaaaagga gtattgcaaa ttgatcctgt tgataattta acgttttctt ggaaaaattt
    22981 gaagttcggt caagccttca tttcgattga atgtacgcaa tccgagttga gtatttcaaa
    23041 tttgtcagaa aagccattga aaataagtga tacgaaaaaa attcttcacg tagaaaaggg
    23101 aaaaacgatt tacattcaaa ggagaaaaag atgagtatac taaaaaatat tacccaattt
    23161 aaaaaaatcc agagtcgagc aatcactccc gaaaatccaa caggcgagaa aggtaaagct
    23221 gcgatgttgc caagcgagct aggaccaagc cgcaaaggtc gtggcgcaat tccgctgact
    23281 tctggtgaag aaactgtgat tgcggatatt actggaacgg gaataattcg tcatatgtgg
    23341 atgacgattc gtgatcgaac agaatttggc agttttgttt tacgtgattt aatcttaaga
    23401 atttattggg atgggtcgga tagcccggct gttgaaagtc ctttagggga tttcttttgt
    23461 aatgggtttg gagagcgttg cgaggtgaac tcgttgccta tagtggttaa tcctacgggg
    23521 ggctttaatt cctatttcga aatgcctttc caaacatccg ctaaaattac gatcgagaat
    23581 ttacatccga aggatatgtc ctcatttttt tatacgataa attacgcttt ggtggacgaa
    23641 ttggaagaaa atagcctata ttttcacgca aattggcatc gggaacgcat taccaaatta
    23701 caggaggatt ataagttaat tgatcgatta aagggtcaag gctattacgt gggtacttac
    23761 cttgcgctta cctgcctaga acgttattgg tggggcgaag gcgagtttaa attctacatt
    23821 gatggggata gtgagtatcc gaccgtaacc tcaacaggtt cagaagatta ttttggcggg
    23881 gcgtgggcct ttcatgagta cgatgagttc ggacgtccac atgcgaaaaa ctattcaaca
    23941 gcctttttag ggtatcctta ccaatcaaat agagatgcca caagagatcg ttttgaaacg
    24001 ggaaaattga atgccgttca tgcctttggt gacgacgcaa tgccacgaca tggtctttat
    24061 cgttggcatc ttcaagaccc catctgtttt accgaagatt tatcggtcac tttacaacaa
    24121 atcggcaacg atgatgttcg cttatttgag cggcaagacg atgttgctag tgtcgcctat
    24181 tggtattcaa cagaagcttc aggaaatact aaacgtcatt tcactgatcg agaacgcttg
    24241 ccgcgttaat gaagtgtttt tcacatattc gaagggagga acctatgatg atatatgggg
    24301 caattgaagc tggagggact aaatttgtct gtgcagtcgg tactgaggaa ttaacgattt
    24361 tggaaagagt cagttttccc acaacaactc cagttgaaac aatgaagcag gtcattgatt
    24421 tttttaaacc ttttaaggaa caattggcag gcatcggggt cggctgcttt ggtccaattg
    24481 atattcaatg caaatcaacg agtttcggtc atatcacatc aacaccaaaa cttgcttggc
    24541 aaaatttcaa ttttgtagga acgctaaagc aatatttcaa tattccgatt gaatggacaa
    24601 cagatgtcaa tgcggcttgc tatggtgaat atgttgctgg ttctggcaaa gggttagcag
    24661 gtgttgcata cttcactgtg ggaacaggta tcggaggtgg tgccttgttc aatgggactt
    24721 tcgtggaagg gttcagtcat ccggaaatgg ggcatatgtt gatcaagcga catccaaagg
    24781 acaatttttc aggaaactgt cccttccacc aagattgttt agaggggatg gcagcaggac
    24841 cagcgattga aaaacgattg ggtgtaaaag gccagaattt attggctgac gattcgtttt
    24901 ggcagattga agccttttac cttgcccaat gtgcatacaa tacaacactg atgctttcgc
    24961 cagatagaat tatttttggc ggtggtgtaa tgaaacaaga acacatgaag aaaaaagttc
    25021 aggataaatt tgttgagctt ataaatggat atgttgaaat accaccaatt gatagctaca
    25081 ttattacgcc cgaattaggt gataatgccg gaataatcgg cggattagca ttggccagaa
    25141 aagcggtaag aaataagcaa ccataattaa tgaatgtttc attgatactc atgtcaaaag
    25201 tatttaaccg agtaatcaaa tgatcaaatg aagttggata aagcgaaaat gaattcaaat
    25261 aaaaaggctc taagtcaaat cgtgttgttt tcattaaatc actgaaagga aatgcttctg
    25321 cgtttccttt tttctttttg ttgtgcgctg tataccttga ggatattcac tggtggcgta
    25381 cacttaaata gtaatatatt gtgttacttt atgtctgtgg taatagttat agttgcttac
    25441 caatgtatgt tcatttttcg aaatgttgac ttcataatcc ttggcttaat gtttgaattt
    25501 ttttggtgat agattttttc agccgtataa aataaatcgt aattctatta tagagagttg
    25561 tgattataaa aagatagcaa gaaaaaaaag aaagtttcta tacattttaa atattttatt
    25621 cctatttcta ttgctaaaaa agtagaaatt ctatatttac ctttaactct cgcttctctt
    25681 gcaaatgtag ttagcatttt aatcgataat aaactcaggt agttatatta ccttgaaatg
    25741 at
//
LOCUS       DACDAF010000032        25254 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.032, whole genome shotgun sequence.
ACCESSION   DACDAF010000032 DACDAF010000000
VERSION     DACDAF010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.032"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..178
                     /locus_tag="IVZ69_001262"
     CDS             <1..178
                     /locus_tag="IVZ69_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP8183360.1"
                     /translation="KTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRA
                     QRRFEGTLRYSLGY"
     gene            complement(313..828)
                     /locus_tag="IVZ69_001263"
     CDS             complement(313..828)
                     /locus_tag="IVZ69_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-keto-6-deoxy-D-glucose epimerase"
                     /protein_id="HAP8183361.1"
                     /translation="MVVVMVKVFDIIKFSDFRGYTAVALDNETLFSIGIEFHIKQINQ
                     GFSHNKYTMRGLHYQSGEHAQGKIVMCLHGEIMNIALDIRQGSSTYGCVYVNTLSESN
                     GKCAYIPRGYAHGYLTMEDNTLVQWCVDNDFNSNAAKCISYESVDIEWPVSRQCFVIS
                     EKDKNVERLSF"
     gene            complement(1010..1621)
                     /locus_tag="IVZ69_001264"
     CDS             complement(1010..1621)
                     /locus_tag="IVZ69_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP8183362.1"
                     /translation="MIDIISAITVNVLTALYQPFLFAVLTAYLFMYWYLFIVDNSRDP
                     KNLKDSVLIWLRYFKASSKFRRLFFLAFYFTLILFKTLLNRNMWMNPLSNVIGQWSLY
                     IIDNATGESRLTTECVENTMLFIPFCMLLLWWRDIKCDIIRTIYVGIKYVFLFSLSIE
                     FTQLFFRLGTFQLSDLFYNTLGGLIGALLYWLFYRLNKYIDLK"
     gene            complement(1647..3098)
                     /locus_tag="IVZ69_001265"
     CDS             complement(1647..3098)
                     /locus_tag="IVZ69_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAP8183363.1"
                     /translation="MTSNNLIVKTLSRYKNTPLPVKAALWFMVCGFLQRGVSMITTPI
                     FTRVLSTEQYGLYSTYLSWESLLLMITSLSLFKAMMNLYVKYDNQEHILSTVSGLTLV
                     LTIFWFVIAIFIKDILAEILGLTPVLVVCMFSYFIFQAEIQCWSLHKRYIYDYKTLLV
                     ATLAVTVGSSVVGCLAVLFISPTAEARALMNVLVTGVVGVAVYISVFRRCKDFKDNEV
                     WNFAVVFCVSLMPHYLSEFILNGSDKIMINYLCGSSDVAIYSVAYSIGALINLVTNSV
                     NSTFAPYQYQKIKSGEYDLLSKRANEVLGLVAAMLFALMLFSKEIVLIFGGQKYIDSV
                     NLIVPICIGIYFNYMFQLFARVQEYFEKKLTVVIPSVLCAIMNIVLNYVFIKLYGYQA
                     VAYTTVFSYMFFCVIHYIFYRKVCKELLDGKNIYDVRGILLISAITIAGGILISIINK
                     FDFIKYLIIAIACVAAIIFRKRLLLLVRRIMSK"
     gene            complement(3122..3853)
                     /locus_tag="IVZ69_001266"
     CDS             complement(3122..3853)
                     /locus_tag="IVZ69_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183364.1"
                     /translation="MEKKMTVIITMAGLGSRFRKIGYAVPKYMINAKGRTLFDWAMDS
                     LVGYNKNVDKYIFVVRQEDNASAFIKEHCAYFGIENVEVIEIDYMTDGQATTCMLAIP
                     YCNQDNEIMVYNIDTYVESNEMKYEDICGDGHIPCFHADGDHWSFAKLNDRNEVIEVR
                     EKVRISDNCTLGAYYFSSAKLYKALYEEYYADSSNMEKNEKYIAPLYNFMIKKGLKVT
                     ISIVDAKKVHVLGTPEELNVFLNQE"
     gene            complement(3871..4266)
                     /locus_tag="IVZ69_001267"
     CDS             complement(3871..4266)
                     /locus_tag="IVZ69_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HAP8183365.1"
                     /translation="MYSEYSFVFDIDGTLCPIKKKDERYEDLVPYENMVEKLRFYKEN
                     GAKITLFTSRNVNSYKGNLGMINANTAKVLLAWLDKWDIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLRCSVDELNEICNSSKKRF"
     gene            complement(4368..6005)
                     /locus_tag="IVZ69_001268"
     CDS             complement(4368..6005)
                     /locus_tag="IVZ69_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HAP8183366.1"
                     /translation="MKVLIPAAKVVEKELQSIGMLPAIIYPINKKIVFDYLYNQYNAI
                     CDSLDIICYEKADKVHRRLKNYHDSRIHICDLPELGDLGQTVYFGLSDEDEPVLINFA
                     DTIVMESMSDIEMDTFYYSEDFVSSTWTYFKINEGIITDIHDKEEAYVSDKREKLFIG
                     VFMFSSSKLLKSCLREAVESRKQGGINSFYRALQLYSERCPLKAVRTEKWFDIGHIDK
                     YYNTKLEVKAREFNHISIDKDRGILKKTSDDKDKFIGEIKWYLKLPADIEYVRPRIFD
                     YSTSYVAPYVDMEYYAYHTVHELYLYGDLKYNQWHDLFSRIKFICSDFKRYTLKDEKI
                     RESLEDMYLRKTMQRFQKLSEDKRFSAFFEKQIQINGRKFISLTGVIELLKNLIPSML
                     YDVNEFCIIHGDLCFANMMVDSNCSFVKVIDPRGKFGKYDIYGDSRYELAKLFHSLDG
                     KYDYIIKDLFTVEYDTECAVIDYTINTRVRDYDLFELFKSVFSDEIKDDFDKIVLIEA
                     LLFLSMIPLHGESFDHQIVMLATGMELLARVSNKVIL"
     gene            complement(6040..7374)
                     /gene="gmhB"
                     /locus_tag="IVZ69_001269"
     CDS             complement(6040..7374)
                     /gene="gmhB"
                     /locus_tag="IVZ69_001269"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HAP8183367.1"
                     /translation="MKTVIMAGGRGSRISELFPDIPKPMIPIDGIPVLERELCSLRDQ
                     GFNDIILTVSYLHEKIEEHFGDGSKLGIKIKYFIEKTPLGNAGALYFLLDELGDEPFL
                     LLNADAVFDVDFRQMIRFHVENNADVTLFTHPNSHPYDSGLIISDDNKKVLQWLAKED
                     QRPEYYKNRVNAGLHVINPKVLRENPLMEIVNKSIVEGGGLPYKIDLDRMILKPLANT
                     GRMYCYDSPEYVKDMGTPDRYRAVIKDFQKGIIVGKNLSNPQKAIFLDRDGTINKYVG
                     FLRNAEEFELIDGVSEAIKIINSLGFLCIVITNQPVIARGEVTVDELNSIHNKLETML
                     GHAGGFLNGIYYCPHHPHKGYAGEVIELKIDCNCRKPKPGLLLEASKDFNINLSQSFM
                     VGDSESDVIAGKNAGCKTVLITEDITLPANYGQDYSVCSLLEFVKNHLCTMQ"
     gene            complement(7416..8525)
                     /locus_tag="IVZ69_001270"
     CDS             complement(7416..8525)
                     /locus_tag="IVZ69_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183368.1"
                     /translation="MNKKEILYNILKKYENLPYVFRNMFGHNISKLVSWKLTADCATV
                     EENSEVYAAFQLRSKDMSDVPVMGLVNCCKDVAIVMQGPLCLKDDFSYNTLAYYKKCY
                     PNALIILSTWKDEDIKALKRIEDLGVIVICSEKPEKPGHLNINYQVGNTLPGIVRAKQ
                     LGAKYVCKTRTDQRIYHPNAMAFFCSLLEQYPVNNEDDWKLIQNQRLLLLSMPYGDMF
                     FPYCLSDFLYFGDVDDMINLFSIPSDVREKGAVSRGVSRREISENNLAPEVQLLRSYI
                     SRMGGNEECSIRAYWEFVKNHVITINKNQIDLYWHKYVGRYSNNTIYGTYYIDDSQDA
                     LHCYNFDFINWLNLYTGKYEYKAEYEKYMDFVWEE"
     gene            complement(8550..9785)
                     /locus_tag="IVZ69_001271"
     CDS             complement(8550..9785)
                     /locus_tag="IVZ69_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183369.1"
                     /translation="MQISKWKIIQFLMVFLMIISSSILKPLGGWLGETMNVRLVTVIL
                     AIVCLLIASLPAFRKNRYLNFCTLLICVVIIAAYIYSDKTIWVKSRESMSLYYVLLAY
                     PLFCTLINQAWNLDSMLNTICGVTFLSYILRTSISLIQKFSGVLLYENIYRECAPENW
                     YRGGFLRINPPCFTIIIIPIALYMIERQVVARRKVKYYLLIASALAYSAVIHGSRSVL
                     VYQIIVLGCYILFKKGSSKRKIAMWVLAGLLVVIFINSTMFSTFVETFTNSTGEYAGS
                     AESRFASVWFFIPKFLQSPLFGTGILTGEEFTFILPGGVRGHLSDIGFFYTITQYGVG
                     ILIFDILFIIKGFKTALLASKVGMTGYQYLAFGITLNVLLTGINIDWFYPIFTPAIPV
                     CLAVIEYIYQECRSVANIE"
     gene            complement(9816..10946)
                     /locus_tag="IVZ69_001272"
     CDS             complement(9816..10946)
                     /locus_tag="IVZ69_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP8183370.1"
                     /translation="MIGYKVSIMKVLMCESQMPENWYSFDLSKELNQYVDLTLLCKRD
                     VPPLDPKIKSKHILYHKSTNKVFSALVFLKSLFLIWKEIRFGDYDIVHLQLMKSLKYE
                     GGLYVLCKRHYKKLIMTVHNVLPHEVREKDRQEHFNIYSNCDGFIVHNRVTEQHLYAE
                     FPELNAKSYVCPHAIYGDVKHISRAYDKDKFEFILFGQIRPYKGIDVLLNAITELPMD
                     VRKKVHFTIAGQQHPKQDSTDYKKMIEDLKVSDCVLYKPERISDEEMDSMFRNADAAI
                     FPYKEIYGSGALLMAYTYCLPTIVSNVPAFMEETEEGKIGLLFENLNSKSLADTIVKY
                     VNLSPAEKSKIEDDIYELVNRKYTWAASAKLTYEAYKQILNE"
     gene            complement(10933..11706)
                     /locus_tag="IVZ69_001273"
     CDS             complement(10933..11706)
                     /locus_tag="IVZ69_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HAP8183371.1"
                     /translation="MLYFVIPLMSAKAANNWEMVSTLFNRTLWSCYNQTDPDFKIIVA
                     CHEIPKLTHEYDDRVEFIQVSEKDAPIPTNQDEKMIDKGYKTHALAMRLRELGGGFAM
                     MVDADDLVSSHLAEYVNSHPQENGFYVKTGYVYFVGDDYMKVLPKFSSGSACIVKYAV
                     EDLPEAYPEVMTANCDDNPWIIRKRHGGVVPACEEQGRPLKPLPFKAAVYVLGTGDNH
                     SLYGKTTKYQTKMREILEMFIAKRKIKGKLKAEFSVDWL"
     gene            complement(11720..12175)
                     /locus_tag="IVZ69_001274"
     CDS             complement(11720..12175)
                     /locus_tag="IVZ69_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="HAP8183372.1"
                     /translation="MNAYKLYKVERWFYLHKMEFFAKIVKALIYVLHNSSISYQTEIG
                     DNCKFLYGGIGCVIGKDTKIGNHVIIGTNVLTGGRSNKPGMPTIGNNVYIATGAKILG
                     NITIGDNVIVGANAVVINDVEPNCSVGGVPARVLKKDIDVNDYCSLNRY"
     gene            complement(12597..13703)
                     /locus_tag="IVZ69_001275"
     CDS             complement(12597..13703)
                     /locus_tag="IVZ69_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP8183373.1"
                     /translation="MKILIVVTMTNNFGKKGSYNSQEIGLARGLAELGHEVIVYKSVK
                     SDEEVGTEQLSNTAMIHYIKCRYVGSNGFLSTKNFDKNADVLIQFADLQLSVPHVYSW
                     TVKNGIKYIPYNGITRSQSGNKYIKTIIEILAHRNYKIYKKNGCVAKNDRVSEKLVQL
                     GVNKVKLAPVCVDFEQLHKNYEAIDFTTLREKWNIPRNVRVILYVGRFEKDKRPLDMI
                     SLFNKLDEHNYLLMVGTGALLEQTKQQINLLGLQNRVKIIERIPNKDIWELYCLSDVF
                     VNLNYTEIWGMVLLEAMYYRLGIIAVNAPGPQNIILDNRYGMLAKSDDEILTFLKDGR
                     FTNDIIDAAYQRVTTEFRWSKSGEIMLSMLEGDK"
     gene            complement(13721..14482)
                     /locus_tag="IVZ69_001276"
     CDS             complement(13721..14482)
                     /locus_tag="IVZ69_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HAP8183374.1"
                     /translation="MEKNMYKRKRDFTVCGIVGVCATTKNEFVREVFSMPTSPVSATV
                     DLVGVPAIISAKENPKIAEMYSQATMAAIDGMPIVKIGRRKGFTCERCAAPDIMGMVF
                     EEGVRQGKTHYFYGGKDNEVLNKLRANLERDYPGIKIVGMYSPPFRPLNEEEDSKICE
                     EINNLNPDFLWVGIGAPKQEMWMWEHQKKIHNTVMFGVGAGFNFFAGTLEKAPEWMEK
                     ASLEWLFRLVKEPRRLWRRYILGGIKYIYYTIESK"
     gene            complement(14558..15556)
                     /locus_tag="IVZ69_001277"
     CDS             complement(14558..15556)
                     /locus_tag="IVZ69_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAP8183375.1"
                     /translation="MKKTIMVTGGCGMIGSNLVKRLVKEGCWDVYVADNLWRGKLEYL
                     NDEDGHPVIDLDTHFFNADLTDYEQAKKVIGTTEYVVHLADVVAGIDYVFKNQGELFR
                     INNLINSNVFDCCRKAGKEKIKGVIYVGTVCSFPLTRQNTLNPEPLREEELFPALPES
                     AYGWSKLMGQLEMGYLEKETGIPCCILMLHNVYGTPTDFGERSQVIPALIRKAINNPE
                     EPFNVWGSGEQGRAFIHVNDIVNALVLALDKGWGHGHIQIGPSHCTSIKEIAYKIIEI
                     SGKDIKPFFDTSKPEGDKARCADYSKAKEILDWEPTVSLEEGLRESYNWIEKQIKG"
     gene            complement(15575..16228)
                     /locus_tag="IVZ69_001278"
     CDS             complement(15575..16228)
                     /locus_tag="IVZ69_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP8183376.1"
                     /translation="MLAEKLNKHIDLLIKRYPTLETIKQDIIDGYLIMEECYLNGGKL
                     LVAGNGGSAADSEHIAGELMKRFKTPRPVSKEFADKLVAIDPVRGPELAKNLECGLTA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRSGDVFLGISTSGNSKNIMSATVVARA
                     LGIKVIGLTGAKGGELATVADVCVKAPEVETYMIQEYHLPIYHCWCLMLEDKFFGNE"
     gene            complement(16238..17248)
                     /locus_tag="IVZ69_001279"
     CDS             complement(16238..17248)
                     /locus_tag="IVZ69_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HAP8183377.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFKENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSAELSYSRTERVTSIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALEGKYADKKKLADEAIYLERVLCNEAGGWQDQIAASYGGFNRI
                     NFNVDGYEVLPVIISPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAILTDKNRNLDDFGRQLDVTWRLKKGTGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQDAVRWAMRDLMYIPFEFENGGTRVIHYTPETYIEKQ
                     NG"
     gene            complement(17267..18517)
                     /locus_tag="IVZ69_001280"
     CDS             complement(17267..18517)
                     /locus_tag="IVZ69_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HAP8183378.1"
                     /translation="MKKQYNIAVAGTGYVGLSIATLLAQHHKVTAVDIIPEKVELINN
                     RKSPIQDDYIEKYLAEKELNLTATLDAKAAYQSADFVVIAAPTNYNSRTQHFDTSAVE
                     AVIRLVMEVNPDAIMVIKSTIPVGYTASVRVKTGSKNIIFSPEFLRESKALYDNLYPS
                     RIIVGTDMDDERLVEDAHTFATLLQEGAIKENVDTLFMGFTEAEAVKLFANTYLALRV
                     SYFNELDTYAEMKGLNTQQIINGVCLDPRIGTHYNNPSFGYGGYCLPKDTKQLLANYA
                     DVPENLIEAIVESNRTRKDFIADRVLQMAGYYNYAEANQYDAGKEKPVVIGVYRLTMK
                     SNSDNFRQSSIQGVMKRVKAKGATVVIYEPTLKDGETFFGSKVVNDLEQFKAMCDSVI
                     ANRYDACLDDIKEKVYTRDIFQRD"
     gene            complement(19863..20036)
                     /locus_tag="IVZ69_001281"
     CDS             complement(19863..20036)
                     /locus_tag="IVZ69_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1972 domain-containing protein"
                     /protein_id="HAP8183379.1"
                     /translation="MNRYVHGTVQKKNRKINGKLLVNPNGYEWLRAKGSYPVPKYCNY
                     SETLMEWYQLIIT"
     gene            complement(20379..21068)
                     /locus_tag="IVZ69_001282"
     CDS             complement(20379..21068)
                     /locus_tag="IVZ69_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HAP8183380.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPPLERE
                     VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYISHRSLMYDLRLILKT
                     FYVIVKPNGAY"
     gene            complement(21113..21877)
                     /locus_tag="IVZ69_001283"
     CDS             complement(21113..21877)
                     /locus_tag="IVZ69_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HAP8183381.1"
                     /translation="MIDLHCHILPGIDDGAENIDASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIDRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEQLFFELLQLGKTPVIVHPERNAHFRKDPNHMLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKMMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(21905..22603)
                     /locus_tag="IVZ69_001284"
     CDS             complement(21905..22603)
                     /locus_tag="IVZ69_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HAP8183382.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENMSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(22616..23395)
                     /locus_tag="IVZ69_001285"
     CDS             complement(22616..23395)
                     /locus_tag="IVZ69_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HAP8183383.1"
                     /translation="MEETISLKEIFETLRKHVITILISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQATSTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAPTQPKATNDKTAPSRRSRSRV"
     gene            complement(23411..24355)
                     /locus_tag="IVZ69_001286"
     CDS             complement(23411..24355)
                     /locus_tag="IVZ69_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8183384.1"
                     /translation="MAKRRRRSRGKKIFLIILAILVVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGHDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYRDAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(24396..25175)
                     /locus_tag="IVZ69_001287"
     CDS             complement(24396..25175)
                     /locus_tag="IVZ69_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183385.1"
                     /translation="MEKPFVKLLATVAVGTGAIVICLFGYHFNNQRQHHQRINYAESA
                     ITNQKDTVTSLSKEVDKLYSTKEKIFLNPEITEETVSNLSHKLSSIKLSADDYDIKES
                     ELPKEAAAIQEEKKAVLTQLEDAESKLKIQTAVNDLFTKNVSNWQQAVDDVVIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSLIEQIRNEKIRAAYASKAETVAQQMGYSNTSY"
BASE COUNT         7759 a         5433 c         3720 g         8342 t
ORIGIN      
        1 aaaaacagtt gagactgttt tttcttcctt agaaaaatta ggttgtcaaa atttcaactc
       61 acgttctgtt aaagggctag agagtagatt tgaaagcata ttactggctt acagtgttct
      121 attaagtcga gcacaacgac gttttgaagg aactttgaga tattctttag gatattaaaa
      181 ttaactagca ccacgggtat atctatatct aaatttagtt ttatgtattc ctcatagaaa
      241 taaccgagca tttgctcggt tattgttctt cttattttcc agtatccttc ttttctccac
      301 agctcatttt aatcaaaagc ttaatctttc cacatttttg tctttctcac ttataacgaa
      361 acactgccga ctgaccggcc attcaatatc tacgctttca taacttatac atttggcagc
      421 attagaattg aaatcattat ctacgcacca ctgaactagc gtattgtcct ccatagtaag
      481 atagccatga gcatatccac gtgggatata cgcacattta ccattgcttt cactcaatgt
      541 gttgacatac acacatccat aagtggaaga tccttgtcga atatcaagtg cgatattcat
      601 aatttcacca tgtaggcaca tcactatctt tccttgagca tgctctccac tctgataatg
      661 tagccctcgc atagtatatt tattatgact aaatccttga tttatttgct taatgtgaaa
      721 ctcaatacca atcgagaaaa gagtctcatt atccaatgca acagcagtat atcctctgaa
      781 atccgaaaac ttaattatat caaacacttt taccataact accaccatgt tatatatttt
      841 accaattttt taattcgctc gacctcattt aaagcaataa aattccctac ctcttgaaga
      901 tataacaaca atgttttagc aaaaatagat ggcatgtaaa gtattcttga tgagattaca
      961 caatcctgtc tgcagaaaaa tattaaccat attaaaattc aaagcagttc tattttaagt
     1021 ctatatactt atttaatcgg tagaatagcc aatatagcaa agcaccaatt aagcccccta
     1081 gggtgttata aaacaaatcc gatagttgaa atgtaccaag cctaaaaaac agttgtgtaa
     1141 attctatact taatgagaat aaaaacacat acttaatccc aacatagatg gtgcgtataa
     1201 tatcacattt aatgtcacgc caccataaca ataacatgca aaaagggata aacagcatcg
     1261 tgttctccac gcattctgtt gtcaatctgc tctctcctgt agcattatct ataatatata
     1321 atgaccactg tccaataacg tttgaaagcg ggttcatcca catatttcga ttaagcaagg
     1381 ttttaaataa tatcaaagta aaataaaacg caagaaaaaa gagtctgcga aatttactag
     1441 atgctttaaa atatctcaac cagattaata cagaatcttt taagttttta ggatctcgag
     1501 agttatcaac tataaataga taccagtaca taaacagata cgctgttaat acggcaaata
     1561 agaacggctg atataatgct gttaatacat ttaccgttat agcagaaata atatctatca
     1621 ttctctatct ctctatgagc aaatgtttat ttgctcataa ttctccttac taaaagtagc
     1681 aatcgttttc taaatataat tgcagcgaca caagcaattg ctataattaa atattttatg
     1741 aaatcaaatt tattaattat tgaaattagg atgccaccag ctatcgtgat tgcagaaatc
     1801 aaaagtattc ctctgacatc atatatgttt tttccatcca atagttcttt gcaaactttt
     1861 ctataaaaaa tataatggat gacgcagaaa aacatatatg agaatacagt tgtgtatgct
     1921 accgcctgat acccatataa ctttataaaa acataattta gtacaatatt cataattgca
     1981 cacaaaaccg atggaataac gacagtgagt ttcttttcaa agtattcctg tactctagca
     2041 aacagctgaa acatatagtt gaaataaata ccgatacata taggtacaat taaattaaca
     2101 ctgtcgatat atttctgccc accaaatatc aacacaattt ctttactaaa tagcattaat
     2161 gcaaaaagca tagccgctac caaaccaaga acttcattag ctctttttga tagtaaatca
     2221 tattctcctg acttgatttt ttgatactga taaggtgcaa aagtggaatt gacagaattt
     2281 gtaacaaggt taattagagc accaatagaa tatgccacgc tgtaaatagc aacatctgac
     2341 gaaccacata agtaatttat cataatttta tcagaaccat tcagaataaa ttcagataaa
     2401 tagtgtggca tcaacgatac acaaaatact actgcgaaat tccacacttc attatcctta
     2461 aaatccttac atcttctaaa taccgatata tacacagcca cgccaacaac accagtcact
     2521 aggacattca ttaaggctct cgcctcagcg gtaggagata taaacagaac cgctaaacag
     2581 ccaactacag atgagccaac agtaactgca agggtagcta ctaataaagt cttataatca
     2641 tatatatatc gtttgtgtaa agaccaacat tgtatttctg cctgaaatat aaaatatgag
     2701 aacatacaga caactagaac tggtgtcaat cctaaaattt ctgccaatat atccttaata
     2761 aaaatagcaa taacaaacca aaaaatagtc agtactaaag tcaatccgga tactgtcgaa
     2821 agaatatgtt cttgattatc atattttaca taaagattca tcatggcttt gaacaaacta
     2881 agcgatgtaa tcatgagcaa taaggattcc cacgatagat aagtgctgta taaaccgtat
     2941 tgttctgtag acaaaactct agtaaaaatt ggggttgtaa tcattgaaac ccctctctgt
     3001 aaaaaaccac ataccataaa ccataatgca gccttaacag gaagtggagt attcttatat
     3061 ctgcttaatg tttttacaat tagattatta ctggtcactg ctattttctc ctaaacacta
     3121 tttattcttg attcaaaaac acattgagct cttctggagt accaagcaca tgaacctttt
     3181 tcgcatctac tatgctaata gtcaccttta accctttttt tatcataaag ttatataatg
     3241 gtgctatata tttttcattc ttctccatat tagaggagtc tgcataatac tcttcatata
     3301 aagctttata cagctttgcc gatgagaaat aatacgcacc aagagtacaa ttatcagaaa
     3361 tgcgaacttt ttcgcggact tctattactt catttcgatc gttaagcttt gcaaaactcc
     3421 aatgatcgcc atcagcatga aagcatggaa tatgtccatc tccacaaata tcttcgtatt
     3481 tcatctcatt tgattccacg tatgtatcaa tattgtaaac cataatctca ttgtcttgat
     3541 tgcaataagg aatagccaac atacatgtag ttgcttgacc atctgtcata tagtctattt
     3601 caatcacttc tacgttttca ataccaaagt aagcacaatg ctcctttata aaagctgaag
     3661 cgttgtcttc ctgacgaaca acaaaaatat acttatcaac atttttattg tatccaacca
     3721 aactatccat ggcccaatca aataaagttc ttcctttggc attaatcata tatttaggaa
     3781 ccgcataacc aatttttcga aaacgacttc ccaaacctgc catcgtaatg ataactgtca
     3841 tctttttttc catagaacta acctccttat ttagaatctt ttttttgaac tgttgcagat
     3901 ttcatttaat tcatctacag agcatctcaa aaactcatca ggtctaaccg ttcgatcatc
     3961 tacatagaag cctttatgcc ccggccaagg cttaccatac aggatttcat catacggaat
     4021 gtcccattta tccaaccacg ccaagagcac ttttgcagta ttagcattta tcattcccaa
     4081 atttccttta taggaattaa cattgcgtga ggtgaacaat gtaattttag caccattctc
     4141 cttatagaat ctcagttttt caaccatatt ctcatacggc accaaatcct catatcgctc
     4201 atccttcttc tttatcggac acaaagtgcc atcgatatca aacacaaaag aatattcact
     4261 atacattttt ctcttccctt ctattgtatt aattaatata atcgtgcctt aatgcctaca
     4321 ttgctaaaac agtattgtaa ccgttattca ttaaggcaca atttatatta gagtataact
     4381 ttattactta ctcttgcaag aagttccata cctgtagcaa gcatcactat ttggtgatca
     4441 aaactttcac cgtgtaatgg aatcatacta agaaatagca acgcttctat caatacaatc
     4501 ttatcaaaat cgtccttaat ctcgtccgaa aagaccgact taaacaattc aaataaatcg
     4561 taatctctta cacgcgtatt aattgtataa tctatcactg cacactcggt atcatattct
     4621 acagtaaata gatccttgat gatataatca tatttaccat ctaaactatg aaatagtttt
     4681 gctaattcat atctgctgtc cccataaata tcatattttc caaattttcc cctaggatca
     4741 ataaccttaa caaaggaaca attggaatct accatcatat tagcaaaaca caaatctcca
     4801 tgtataatac aaaattcatt tacatcatag agcatacttg ggataagatt ctttagaagt
     4861 tcaattacac cggttaaaga aataaactta cgaccattaa tttgaatttg tttctcaaaa
     4921 aaagctgaaa atcttttatc ttcagacaat ttttgaaatc tctgcatggt ttttcgcaaa
     4981 tacatatctt ccaatgactc tctaatcttt tcatctttta aggtgtatcg cttaaaatcg
     5041 ctacagataa actttatacg gctaaacaga tcatgccact ggttatattt taaatcacca
     5101 tataagtata actcatgaac cgtatgatat gcataatatt ccatatcaac atagggagct
     5161 acgtaagatg tagaataatc aaaaattcta ggtcttacat attcaatatc agcaggaagt
     5221 tttaaatacc actttatttc tccaataaat ttatccttgt catcgctagt tttcttcaat
     5281 atccctcgat ctttatctat agagatatga ttaaactctc gtgctttaac ttccaacttt
     5341 gtattgtaat atttatcgat gtgtccaata tcaaaccact tttctgttct tacggccttt
     5401 agcggacaac gttcgctgta tagctgtaaa gcccgataaa atgagtttat tcccccctgt
     5461 ttccgactct caactgcctc tcttaagcaa ctcttcagaa gttttgacga agaaaacata
     5521 aatacgccaa taaataattt ttcacgttta tcggatacgt aagcttcctc tttatcgtgg
     5581 atatcagtaa ttattccttc attaatttta aagtatgtcc aagtactcga cacaaaatct
     5641 tcagaataat agaatgtatc catttctata tcagacatac tctccataac aattgtatct
     5701 gcgaagttaa ttagaacagg ctcatcttca tctgataacc caaaatacac ggtttgccct
     5761 agatccccta attcaggaag gtcacatata tgaattctgg aatcatgata gtttttcagt
     5821 cttctatgaa ccttatccgc tttttcataa cagataatat ccaatgaatc gcagattgca
     5881 ttatactgat tatacaaata atcaaagaca atttttttat taattggata gataattgct
     5941 ggtaacattc ctatactctg caattctttt tcaacaactt ttgctgctgg aattaatacc
     6001 ttcatctaat tactcctttt acaagtttca ctaaaccaat tattgcatag tgcataaatg
     6061 atttttaaca aattctaaca atgaacagac actatagtct tggccataat tagcaggcaa
     6121 ggtgatgtct tctgtaatca gtactgtctt acaaccagca ttttttccag caattacatc
     6181 actttcacta tctccaacca taaatgattg acttaggttt atgttaaaat cctttgatgc
     6241 ttctaataac agtccaggtt ttggcttgcg acaattgcaa tcaattttta attctataac
     6301 ctctcctgca tatcctttat ggggatggtg cggacagtaa taaataccgt ttaaaaatcc
     6361 accagcatgc cctagcattg tttcaagctt attgtgaata ctattaagct catcaacagt
     6421 aacttcacct cttgcaatta caggctgatt tgttataaca atacacagaa aacctagaga
     6481 attaataatt ttaattgcct ccgatactcc atcaattaac tcaaattctt ctgcatttct
     6541 caaaaaacca acgtatttat taatcgttcc atctctatct aaaaagattg ctttttgtgg
     6601 attggataga tttttaccaa caataattcc cttttgaaag tccttaatta cagctctata
     6661 tcggtccggt gttcccatat ctttaacata ctctggagaa tcgtagcaat acatacgccc
     6721 tgtgttagcc aatggtttca gaatcattct atctaaatca attttgtatg gtagcccccc
     6781 accttcaact attgatttat ttacaatttc cattaatgga ttttctctca acaccttcgg
     6841 atttataaca tgaagacctg catttactcg gtttttataa tattcaggtc tttgatcttc
     6901 cttcgctaac cattgaagca ctttcttatt gtcatcggat ataattaatc cactatcata
     6961 cggatgtgag ttaggatgcg taaacaaagt aacatctgcg ttattctcaa catgaaatct
     7021 aatcatctgc ctgaaatcaa catcaaatac tgcatcagca ttcaaaagta aaaacggttc
     7081 atcacccagt tcatccaaca aaaaatacaa tgcacctgca ttgccaagtg gagttttttc
     7141 aataaaatat ttgattttaa ttcctaattt tgaaccatct ccgaaatgct cctctatttt
     7201 ttcatgcaaa taggaaacag tcaaaataat atcattaaag ccttgatctc taagcgaaca
     7261 caattctcgt tctaaaactg gaatgccatc tataggaatc attggcttag gaatatccgg
     7321 aaacaattcc gaaattcggc ttcctcgtcc gcccgccata attactgttt tcataatatg
     7381 cccttcccta aagtactttt tactataaaa gttaattact cttcccaaac aaagtccata
     7441 tatttttcat attctgcttt gtattcgtat tttccagtgt acaaattcaa ccaatttata
     7501 aaatcaaaat tatagcagtg aagtgcatct tggctatcat caatataata cgtaccataa
     7561 atagtattat ttgaataacg acctacatat ttatgccagt acaaatcaat ttgatttttg
     7621 ttaatagtaa taacatggtt ttttacaaac tcccaatatg ccctaataga gcactcctca
     7681 ttgcccccca ttcgtgaaat atagcttcga agaagctgaa cttctggagc taaattattt
     7741 tcagatatct cccttcttga gactcctcta gacacagctc ccttttctct cacatcacta
     7801 ggaatcgaga agaggtttat catatcatca acatcaccaa aatacaggaa gtctgacaaa
     7861 caatacggga aaaacatgtc tccatacggc attgatagta acagtaatcg ctgattttgt
     7921 attaatttcc aatcatcttc gttattaaca ggatactgtt caagtaaact gcagaaaaac
     7981 gccattgcat ttggatggta tattctttga tctgttctag ttttacaaac atactttgca
     8041 ccaagctgct ttgctctgac tattccaggc aaagtgtttc caacttgata attaatattt
     8101 aagtgtccag gcttttcagg tttctcacta caaataacta taactccaag atcctctatc
     8161 cttttcaatg ccttaatatc ttcgtccttc catgtcgaaa gaataattaa agcatttgga
     8221 taacatttct tatagtaggc cagagtatta taagagaaat catcctttaa acatagtggc
     8281 ccctgcatta caattgctac atctttgcaa caattaacta aacccatcac tggaacatca
     8341 gacatgtcct ttgagcgcaa ttgaaacgct gcataaactt cagaattttc ttctactgtt
     8401 gcacaatcag cagtcaattt ccaagatacg agtttactta tattatgacc aaacatgttc
     8461 ctaaacacat atggtaaatt ttcgtacttc ttcaatatgt tatataaaat ctctttctta
     8521 ttcatgagat gcactcctat taatatttcc tattctatgt tagccacact tctacattct
     8581 tgatagatgt attctataac cgctaagcat acaggaatag ctggagtaaa tatcggataa
     8641 aaccagtcta tattaatccc tgttagcaag acatttaatg taattccaaa tgctaaatat
     8701 tgatagccag tcatacccac ttttgatgca agtaatgctg ttttgaaccc ttttataata
     8761 aacagaatat caaatataag tatacctaca ccatattgag taattgtata gaaaaatcca
     8821 atatcagata ggtgtcctct aactcctcct ggtaatataa acgtaaattc ctcaccagta
     8881 agaataccag taccgaacaa aggcgattgc aaaaatttag gaataaaaaa ccaaactgaa
     8941 gcaaatcgag attcagcaga tcctgcatat tcacctgtac tgtttgtgaa agtttcaaca
     9001 aatgttgaga acatggtcga attaataaat atgactacaa gcaacccagc taaaacccac
     9061 attgcaattt ttcttttcga agaacctttc ttaaaaagga tatagcaacc aagtacaata
     9121 atttgataga caaggacaga tctagaacca tgaataacag cagaatatgc cagtgcgcta
     9181 gcaatcagta aataatattt tacttttctt ctagctacaa cttgtcgctc aatcatatac
     9241 aaagcaatcg gtattattat aattgtaaaa catggtggat taattcttaa aaagcctcca
     9301 cgataccaat tttccggggc acactcacga tatatgtttt catagagaag tactcctgaa
     9361 aatttctgaa taagtgaaat agatgttcta agaatgtatg aaagaaatgt tacaccacat
     9421 atcgtattta gcattgaatc caaattccac gcttggttaa ttaaagtaca gaacaatgga
     9481 tacgccaata atacatagta taaactcata ctttccctag atttaaccca tattgtctta
     9541 tctgagtaga tgtaagctgc tattataaca acacaaatca gtaaagtgca gaaatttaaa
     9601 tatctatttt ttctaaatgc tggtaatgag gctattaaca aacatactat tgctagaatg
     9661 actgtcacaa gtctaacgtt catcgtttct cccaaccagc cgcccaaagg cttcaatatg
     9721 cttgatgaga taatcattag aaagaccatt agaaactgta tgattttcca tttactaatc
     9781 tgcatgttaa ttattattcc tttctaattg ttttactact cattcaaaat ttgtttgtat
     9841 gcctcgtatg tgagttttgc agatgccgcc caggtatact tgcggtttac aagctcatat
     9901 atatcatcct ctattttgct tttctcagct gggctaaggt tcacatactt tacaattgtg
     9961 tctgctaggc tcttagaatt caaattttcg aaaagtaacc ctatctttcc ttcctcggtt
    10021 tcttccataa aagcaggtac attactaaca atagttggta agcaataagt gtatgccata
    10081 agaagcgctc cacttccata gatttcttta tatggaaata ttgcggcatc tgcatttctg
    10141 aacatactgt ccatttcttc atcagaaatt ctctctggct tatatagaac acaatctgaa
    10201 acctttaaat cttcaatcat ttttttatag tcagtactat cctgtttagg atgttgttga
    10261 cctgctatgg taaaatgaac tttctttctt acatccattg gaagttctgt gattgcatta
    10321 agcagtacat caattccctt atatggacga atttgtccaa acaagataaa ttcaaactta
    10381 tctttatcat acgctctaga tatatgttta acatctccat agatagcatg tggacaaaca
    10441 tatgactttg catttaattc tgggaattca gcatataaat gctgttctgt tactcgattg
    10501 tgaacaatga aaccatcaca atttgaatat atattaaagt gctcttggcg atccttttca
    10561 cgaacctcat gtggtaacac attatgaact gtcataatta attttttata gtgtctctta
    10621 cataaaacgt acaatccgcc ttcatatttg agacttttca tcaattgcaa atgaacaata
    10681 tcataatcac caaatcttat ttccttccaa attaagaaca agcttttcag aaaaacaagt
    10741 gccgaaaaca ctttatttgt acttttatga tacaaaatat gtttgctctt aattttagga
    10801 tctaaaggag gaacatcacg cttacacagc aatgttaaat caacatattg attaagttct
    10861 ttagaaagat caaacgaata ccaattctct ggcatttggc tttcacacat caataccttc
    10921 ataatactca ccttataacc aatcaacaga aaattctgct ttcagttttc ctttaatttt
    10981 acgttttgct ataaacattt ccagtatctc tcgcattttc gtctgatatt ttgtcgtttt
    11041 accataaagc gagtgattgt cccctgttcc taatacatat actgctgctt tgaatggaag
    11101 aggttttaat ggacgccctt gctcttcaca tgctggaaca acgcccccat gtcgttttct
    11161 aatgatccat ggattatcat cacaatttgc tgtcataact tccggatatg cctcaggcag
    11221 gtcttccact gcatatttta ctatacacgc acttcctgat gagaactttg gtagaacctt
    11281 catataatcg tctccaacaa agtacacgta tcccgttttg acataaaatc cattttcctg
    11341 gggatgggaa ttcacatatt ccgccaaatg agaacttaca agatcatctg cgtcaaccat
    11401 catagcgaaa ccgccgccca actctcgcaa acgcattgcg agagcatgtg ttttataacc
    11461 cttatcaatc attttttcgt cttgatttgt gggaataggg gcatcctttt cgctaacttg
    11521 aataaattca actctgtcat catattcatg cgtgagttta ggaatttcat ggcaagcaac
    11581 aatgattttg aaatcaggat cagtctgatt ataacacgac cataatgttc ggttaaataa
    11641 ggtactaacc atctcccaat tgtttgctgc cttcgcactc attaaaggaa taacaaaata
    11701 caacatacaa tctctccttt tagtaacgat tcaaactaca ataatcattt acatcaatat
    11761 cttttttcaa tactctagcc ggaacgcctc ctaccgaaca attaggttca acatcattaa
    11821 tgaccacagc attagcccct actattacat tgtcccctat tgtgatatta cctaaaattt
    11881 ttgcgccagt agcgatatat acattgtttc caattgtagg cataccaggc ttattggatc
    11941 taccaccagt cagtacattc gttccgatta taacgtgatt acctattttt gtatcttttc
    12001 caattacaca acctatgcca ccgtataaga acttacaatt atctccaatt tctgtttgat
    12061 atgaaattga gctattatga agtacataaa ttagtgcctt tacaatcttg gcaaaaaact
    12121 ccattttgtg taagtaaaac catcgttcta ctttgtataa tttatatgca ttcatgtttt
    12181 atctccccat ctttttagca ggtacccccc acacttcgta gggtggaata gacctcaata
    12241 ccactgtatt tgcagcaact acagcacctt ccccaacgca taattctgtg ttagatttac
    12301 aaagaatttt agcacccaca cataaaacag cgttcttttt tactcgaatg atgatacgtt
    12361 cattactatc tgctcaacca cacgtcacat tctgatagac tttaacacca tcttcaagga
    12421 ttgtgtcaga atgaatcaca gtgcctacag aattatgaac aaattcaaca gagttcccta
    12481 tctgtgcacc tttaccaata caacaaccaa gaattttggc tatttttctc gtgcaattat
    12541 caactatgtt taaagcatat cgattcctca atgccattaa tttcgttact tccatatcat
    12601 ttatcacctt ccaacatgct aagcataatt tctcccgact ttgaccatct aaattctgta
    12661 gttacacgct gatatgctgc atctatgata tcgttggtaa atcgtccgtc ttttaagaat
    12721 gtcaaaattt catcgtcaga tttagccaac attccatatc tattatccaa aataatattc
    12781 tgtgggccag gtgcattaac agcaataatc ccgaggcgat agtacattgc ctctagcaaa
    12841 accatacccc aaatttcagt atagtttaga tttacaaata catccgataa gcaatataac
    12901 tcccaaatat ctttgttagg aatacgctca attattttta ctctattctg cagtccaagt
    12961 aaatttatct gctgcttcgt ttgctcgagt aaagcaccag ttcctaccat cagcaaataa
    13021 ttatgctcat caagtttatt aaataaacta atcatatcta acggtctttt atccttttca
    13081 aaccgtccta catataaaat aacacgaaca ttgcgaggaa tattccattt ttctctgaga
    13141 gtagtaaaat ctattgcttc gtaattctta tgtaactgtt caaaatccac acaaacagga
    13201 gcaagtttca ctttatttac tcctaattgt actaattttt cagaaactcg atcatttttg
    13261 gcaacacacc catttttctt ataaatttta taatttcgat gcgccaatat ttcaataatt
    13321 gtctttatat atttattgcc actttgactt cgcgttatcc cattataagg tatatatttt
    13381 attccatttt ttacagtcca tgagtataca tgaggtactg atagttgaag gtccgcaaat
    13441 tgtattagaa catccgcatt cttatcaaaa ttctttgttg ataagaatcc atttgatcct
    13501 acataacgac acttgatata gtgaatcatc gccgtattgc ttaattgctc tgttccaact
    13561 tcctcatcac tttttacact tttatataca ataacttcgt ggcctaattc agctaaccct
    13621 cgagctaatc ctatttcctg agaattatag gaccccttct taccaaagtt attcgtcatt
    13681 gtaactacta taagtatttt catctatttt tattgccccc ctacttagat tcaatagtat
    13741 agtagatata ctttatacct cccaagatat accgcctcca tagtctacga ggttccttta
    13801 ccagtctaaa taaccactct agactagctt tttccatcca ttcaggagct ttttccaaag
    13861 tgcccgcaaa aaagttaaag ccggcgccta caccgaacat tactgtgtta tggatcttct
    13921 tctggtgttc ccacatccac atttcttgct taggcgcacc aataccaacc cacagaaaat
    13981 ctggatttaa gttgttgatt tcctcgcaaa tcttgctatc ctcttcttca tttaacggac
    14041 gaaatggtgg ggaatacatt ccaacaattt tgattcccgg gtaatctctt tctaggtttg
    14101 cacgaagctt atttaacact tcgttatctt ttccaccata gaaataatgt gtttttccct
    14161 gtctaacgcc ttcttcaaaa accattccca taatatctgg tgcagcacat cgttcacagg
    14221 taaatccttt gcgccgtcca attttaacaa taggcatacc atctattgca gccattgtag
    14281 cctggctata catttcagca attttgggat tttcctttgc cgaaataatg gccggcactc
    14341 ccacgagatc aacagtcgca cttaccggag atgttggcat ggaaaaaact tcccttacaa
    14401 actcgttctt tgtagtagca caaacaccta ctattccaca cacagtgaaa tcacgttttc
    14461 ttttatacat attcttttcc atctcagtac atccttactc atatgttctt cctccgcatc
    14521 ctctaattac acggaggaag aacagcttat atacttatta acccttaatc tgcttttcaa
    14581 tccaattgta ggattcacga agaccctctt ccaaagaaac agtaggctcc caatccaaaa
    14641 tctctttcgc cttagaataa tctgcgcaac gagccttatc accttcaggc ttagaagtat
    14701 caaagaaagg cttgatgtct ttgccagaaa tttcaatgat cttatatgca atttccttga
    14761 tggaagtaca gtgagaaggg ccaatctgaa tatgaccatg accccaaccc ttatccaggg
    14821 cgagcaccaa tgcatttacg atatcattga catgaatgaa agcacgtccc tgctctccgc
    14881 taccccacac attaaaaggc tcttcaggat tattgattgc tttacgaatc agagcaggaa
    14941 taacctgact acgttcgcca aaatcagtag gtgtgccata aacattatgg agcatcagga
    15001 tacagcacgg aattccggtt tctttttcca aataccccat ctccaactgg cccatcagtt
    15061 tgctccagcc ataagcagac tcaggaagag cagggaacaa ctcctcttca cggagaggct
    15121 caggattcaa agtattctgt ctggtcagag ggaaggagca tacggtacca acatagataa
    15181 cacccttgat tttctccttg ccagccttac ggcaacaatc aaaaacatta gaattgatca
    15241 gattattgat tcggaacaat tcgccctggt tcttaaacac atagtcaatg ccagccacaa
    15301 catcagccag atgaactaca tactcagtcg taccaataac ctttttagcc tgctcataat
    15361 cagtcagatc agcattgaag aaatgagtat ccaggtcgat gacaggatgc ccatcttcgt
    15421 cgttcaggta ctccaacttt cctctccaca gattatcagc tacataaaca tcccagcagc
    15481 cttccttcac cagtctctta acaagattgg agccaatcat accgcaacca ccggtaacca
    15541 taattgtctt tttcatttaa cattcctcca aattttattc gtttccaaag aatttatctt
    15601 ccagcatcaa acaccaacaa tgatatatcg gcaagtgata ctcttgaatc atgtatgttt
    15661 caacttcagg agccttaaca caaacatctg ctaccgtggc aagttcccca ccctttgcgc
    15721 ccgtcaagcc aataactttt ataccgagag ccctagcaac aacagttgcg ctcataatat
    15781 tcttgctatt tccggacgtc gaaataccaa ggaatacgtc accagatcta ccaaagccaa
    15841 acagctgctg tgcgaagaca cccaaaccat cgacatcatt aatataagca gtagacaatg
    15901 cttcgtgtgc gaccaaagga attgccgtta aaccacactc gagatttttg gctaattccg
    15961 gacctcttac agggtcaatt gcaactaact tatcggcaaa ttccttactt acaggacgtg
    16021 gcgtcttaaa ccgcttcatc aactcgccag caatatgttc cgagtcagcg gctgatcctc
    16081 cgtttcctgc cacaagaagt ttaccaccat tcaaatagca ttcctccata attaggtatc
    16141 catcgataat gtcctgttta atcgtctcaa gtgtaggata tcgtttaatc aataagtcaa
    16201 tatgtttatt aagtttttcc gctaacattg ttactcctta tccattctgt ttttcaatat
    16261 aagtttccgg cgtgtagtga ataactctag ttccaccatt ttcaaattca aacggaatat
    16321 acatcaaatc acgcatagcc caacgaactg catcctgttt ctcaggttgt acatagaaaa
    16381 ccaagaaacc tccaccacct gcaccgagca actttccgcc taaagcacct gcagccatac
    16441 ccttttcata tagttcatca atgcttcctg tactaattgc tccaccagta ccttttttca
    16501 atctccaagt aacatcaagc tgtctaccga aatcatctaa atttctgttc ttatcagtaa
    16561 gaattgcctc agcttcatct acaagctcat acatcttttt cagtcttact ctcttatcct
    16621 ctgtgccact gacgttgtta gccttttgaa catcagaaga aaatctagtg aatccggtaa
    16681 agaacatcat cagattgttg ttaagctgct ttttacgttc aggcgaaata atgacaggca
    16741 gcacctcata accatccaca ttgaaattaa ttcgattgaa cccaccataa gatgcggcaa
    16801 tctgatcctg ccatccaccg gcttcattac acagaactct ttcaagataa atggcttcat
    16861 cagcaagttt cttcttgtca gcatacttac cctccagtgc ataaaaagca ttcaacatac
    16921 caactgcaaa agaactggat gtacccagac cagagcgagc aggtaaatca gcttcgtatg
    16981 taagccgaat ttcatgcata tcgagcattt tcatcgcatt acgaatcgca ggatgctcaa
    17041 tatcttcaat gctagttact ctctcagtac gagaataaga taactcagcg ctgtaatcaa
    17101 aaaatctagg cagatgtctc acattcacat aacagtactt atcaaaagta gtagaaagaa
    17161 ctgcaccgcc attctctttg aaataatcct ccatatccgt tccaccgcca aaaaaagaca
    17221 tacgaaacgg tgtttttgta ataatcataa atactctctc ctaatcttag tctctctgga
    17281 agatatcacg ggtatatact ttttccttaa tgtcatcaag gcaagcatcg tagcgatttg
    17341 ctataacaga atcacacatt gccttaaact gttccaaatc attcacaacc ttactgccaa
    17401 agaaagtctc tccatctttc aaggtcggct cataaatcac aacagttgca cctttagctt
    17461 ttacacgctt cataacgccc tggatagaac tctggcggaa gttatcagaa ttggatttca
    17521 tggtcaaacg gtaaacacca atcacaacag gcttttcttt gccagcatca tactgatttg
    17581 cttctgcgta attgtaataa ccagccatct gaagtacacg atccgcaata aagtccttac
    17641 gagtacggtt agattcaacg attgcctcga tcagattttc aggaacatct gcgtagttgg
    17701 ccagaagctg cttggtatcc ttcggcaggc aatagccacc gtaaccaaag gaagggttgt
    17761 tgtaatgagt accaatacga ggatcaaggc aaactccatt aatgatctgc tgagtgttca
    17821 agcctttcat ctctgcataa gtgtccagct cattgaagta gctgacacga agagccagat
    17881 atgtattggc aaacagctta acagcttctg cttcagtaaa gcccatgaac aatgtgtcca
    17941 cattctcttt gattgcgcct tcctgtagca gtgtagcaaa agtgtgtgca tcctcaacca
    18001 aacgctcatc atccatatcg gtacccacaa taatacgcga aggatacaga ttgtcataca
    18061 gtgccttact ttcacgcagg aactcagggc tgaaaataat attcttgcta ccagtcttta
    18121 cacgaacaga agcggtgtat ccaacaggaa tggtggactt aataaccata atggcatcag
    18181 gatttacttc catgaccagc ctaataacag cctcaacagc ggatgtgtca aaatgttgag
    18241 tgcggctatt gtagttagta ggagccgcaa taacaacaaa atccgcagac tggtatgctg
    18301 cctttgcatc caatgttgcg gtcagattca gttctttctc agccaagtac ttttcaatat
    18361 aatcatcctg gattggagat ttacggttat taatcagttc aaccttctct ggaatgatat
    18421 ccaccgctgt aaccttatgg tgctgtgcca acagagtggc aatactcaaa ccaacataac
    18481 cggtgccggc gactgcaatg ttatactgtt tcttcataat atttcctctt tccaccactg
    18541 ctgtggtcac tactttctta acaaaatgct gtttgtgaac agtaacctgc tatttatata
    18601 aaacagcccg aaagctgtgt tcattcatac ttaaaacagc cagctcctac gccggcaaat
    18661 tcaatttttc ataaatcccc tacccgttta gggttatatt gcaagtttga gtcattttta
    18721 ttgacctcgt ttggggttat aatacatttt cgcattgaaa tgtacctaca ttttccactc
    18781 aaccagtcac caaaaagttt ataaattcac ttattaccct ctattcttac tccaaaggta
    18841 tgtttaacat cgctttattg acctattttc accccaaatg gaagtttgtt tggtacatta
    18901 ttggtctatt cccaccccaa actgtctatt ttgagcgagt ttttgttttt tatcattgca
    18961 cattttcaag gctcaaattc taagcggatt tactggcagg gagacattgg taaatacttg
    19021 aacaatttca cggctttcat catcacatcc tacgataata attctaattg gataaagatt
    19081 atcattaata atctactttc acgtaaaaat tctgaactaa ataaaatcta ttgataatat
    19141 ttttttcttc cactttttgt atatcctaca ggtatagtgg atttaattat ccccaatgcc
    19201 tctgaagtaa cagacatcac taattcaata acacattcac taccatagtt tgtaggaaca
    19261 aaaatgacaa caaaatctgc ttccttatgt gatgtttttc catctgtcca aattttatta
    19321 ccaatgaaat ctagtttaaa atccctctta gaaactagtt cactctatat ttttattcag
    19381 tttcattagt tctgtttttt tgtcttcagt caccatatac atatatatct taattatcta
    19441 tccatttcat cctacgcatt cttgcgtaaa tacaattcac tctgttgagc tgatataaat
    19501 cattggtggt acaaagataa aatgataact gtttctatac ctccaaaaat tccagtaaat
    19561 atatctatag atagtttcaa aaaaaattgt cttagtttca taatatttaa gatagtggta
    19621 catactttat aacaacgtac ttttccaaat attattttcc gttatgaaca tccaatatat
    19681 tacaaagttt aaaagtttag atgaactata atcttcattt ctgcacagtg gataataaat
    19741 tcttatagat aaaaaatagc ctcttctaaa gtcacaaata ccttactccc acattttaag
    19801 taaacactct gcagcattct ctttgttata aaatgataga tattcctcaa ttttatctct
    19861 tattatgtta ttatcagttg ataccattcc attaatgttt cagaataatt acaatatttt
    19921 gggaccggat aactcccttt tgctcgtaac cactcatatc cgttaggatt cactaaaagt
    19981 ttaccgttta tttttcgatt ctttttttga accgtcccat gaacataccg attcaacaag
    20041 ctaaattata aaaattggtg tgctgtcatt attttttgga aaatttatta atggctatca
    20101 atatactttt gtatcatact aaatagctcg tcagttccta tatcggatat accaatatta
    20161 aagcatttag atcattatat ttaagagtgg tatcatccca aaatttcgaa tattttcttt
    20221 tatataagaa taatgatact gaattgcccc attcaccttt ctttttttag attttctaca
    20281 agtgattcaa accctccata attacagtta ttacttttga aacgataata tgaacatgtg
    20341 taatcttttt tattaacaat ccatcattct atccctaact aatatgctcc attgggcttg
    20401 acaataacat aaaacgtttt taaaatcaac ctcaagtcgt acattaaact tcgatgacta
    20461 atatactcta aatccaactc aaccatttta tggaaactaa cattatttct atcactaact
    20521 tgccacaaac ctgaacaacc aggttttaca tacaagcgtt gaagatcata tctcgtgtac
    20581 tcagctactt ccctctccaa aggtggccgt ggaccaatta gactcatatc gccttttaaa
    20641 acattccata gctgtggcaa ttcatcaatg cttttggcac ggataatttt acctatttta
    20701 gtgacacggg gatcttcttt catcttgaac attgcacctt ctatttcatt ttgatcaagt
    20761 aattcttcca atttttcttc agcatctaaa cacatcgaac ggaatttata cattttgaat
    20821 gtttttccat ttttaccaac acgtgtatgg caaaaaaata tcggacttcc tggctcttct
    20881 tttctgattc gataagctac atagaacatc aaaggagaag ctaaaatcaa accaataatg
    20941 cttcctacaa tatcaatcat tcttttaaaa aataaataga tatatcgttt ttcaactttt
    21001 tctttatcca accaaacttg attaggatgt acttcactaa tacgagataa taaatcttca
    21061 ctttccatac tttccctctc tcctcatttc ctttttatct acgaataaag aactaaaata
    21121 aaccaaactt cttctttttt acctcttcat agactggata actgatttca tccccgttga
    21181 tcagatcctt tgcgacttgt ttcatctgta ctactttttc cttaccaaag tccttagcaa
    21241 tctgctcata gcactctttt aagtaaaagg tacgcttaga gaccccatgg gcatcagaag
    21301 cagccatctg cacaagatta tgtttgacca tcattttggc tgttttctgg atgtcttttc
    21361 caaatacacc gacataactt ggtgcggtga gttgggccaa gcatcccata tctaggaatg
    21421 gcagcatatg attcgggtct ttacgaaaat gcgcgttgcg ttctggatgg acgatcactg
    21481 gtgtctttcc tagttgtaac aactcaaaaa agagctgttc tgcatataac ggcacttcca
    21541 gtgtcggaaa ttcgattaga agatatgtat catctaaatc tgtaaataaa atttcatctc
    21601 ggtcgatgtc ttcgatcagt gttccggtaa tacgtacttc ttgtccttcc aataacgtca
    21661 aaggcaattg tcttttctct aattctgctt gtaacgaagc gactagagaa atgacttgtg
    21721 atttttcatt gctgtatttt ccattattat gatggggtgt gcataaaata tgtgtgatcc
    21781 cttgttgaat cgctttttca gccatggcga tactggcatc tatgttttct gctccgtcat
    21841 cgattcctgg caggatatgg caatgtagat cgatcatttc tcttgtctcc tctcttttta
    21901 tttcttaatt cccgtagtaa tagccagcat ctttgctgtg ttctgcccca ttgtatacaa
    21961 caccaaggac tcgcgcttgt accatatcca gcaattcttt tgctttagtc aatgattctt
    22021 tccgtgacat attttcacgt acgaccaata aggtgccatc cgttttggaa gacatgatct
    22081 gtgcatctgt tacggcaact actggcggca tgtcgaagat cactacatca aatagttgtc
    22141 ttgcttctgc taaaatctga tccattcttg gcgaacttag tagttctgat ggatttggtg
    22201 gtttaggtcc acttggcaga atcgacaaat tctcgactgg tgttcgttgg atctcatctg
    22261 ctacacttcc tgatgaacta agaacggtac ttaatccgct tgcgttgttc aacttgaacg
    22321 ttttatagat gacgggctta cgtaagtctg catcgactag cagcacccgt tgaccagatt
    22381 tggcaaaaac aacggcaatg tttgctgcag tggtcgattt cccttctcca ggtcctgatg
    22441 aagtcacaac aatcgtttta atttgctgac cagctgcgga ggcaaactgg atattcgtcc
    22501 gaatcgtacg atattgttca gcgattggtg aagaggggtt tgtgagtgtg accaaactga
    22561 ctgcatgagt ttgggctgct ttttgtttct gtgttcgtgc catttttctt tcctcctaga
    22621 ctcttgagcg gcttctgcgt gatggcgctg ttttatcgtt tgtagctttt ggttgtgtcg
    22681 gagctggtcc ttttttacgg ataccagcat tcaattcttt cgctgacatt tctggtacag
    22741 tccctaagat cgggaagccc aatgtatccg tcacatattt ttcatctttt actgtccggt
    22801 cgagtaattc aaataagaaa gctagaccta cgcctaccat cattcctaac actaagccaa
    22861 tcactagatt caatttatta tttggcgaaa caggtgtcgt attggcaact gcacctgaga
    22921 tgatcgagat tttatcgaca ttcatcacgt ctttggcgtt ctcttggaat acttgtgacg
    22981 ttgtattagc gatttgttga gccgtcactg catttgtgct tgttgcttgg atcgagaaca
    23041 tttgtgaatt ttgtgactga ttgacggaga tggcatcttt gatttgtcca gcagtcattt
    23101 ttacattgtc ttctgtttct aaacgatctt tgacttcatt tagtactaga tcactgacga
    23161 tcatatcctt atacgtattg atcatttgca ggttcgtatt gacatcattg acatttgcag
    23221 tatctgattg cggcagtgtc acgatcaatt gggcttgtga gctgtatttt ggcgtcaaga
    23281 tgaaaaacgt cacgatgcct gagatggcca agccagcaaa cattgagatg aggattgtta
    23341 tcacgtgttt gcgtaatgtt tcaaaaattt ctttcaagct gattgtctct tccatttttt
    23401 ctccactttc ctatttattc tctagattca tttgatcttt taattctttt ttcacacgat
    23461 caagttcttg atcgctgact ttttggtatg agatattgtc ttgcatgaag ccttctcctt
    23521 gcagctgatc ttgcttgatc gtaccaaatg catcccgata atctaaagca atctttttca
    23581 tttcatcaaa gctcatgtct gttttcatat tcgactctag agcattcaaa acggattgat
    23641 agttgcttac accgttcaga ctcaacactt ttttcgctac accttctacg atctttcttt
    23701 gacgttcttg tctgccgtag tcaccatttg gatcttcata acgcatacga gaataagaca
    23761 atgcctgatc cccgttcaat gtgattttac cgatcgtaaa atcatagcca tcttgtgaga
    23821 aggtgaggtc attattgact tcgataccac caactgcatc aacgagttct tttagacctt
    23881 tcatattgat tgaaacatag tgatcgattg ggatgtctac atatttttgt acggtatcca
    23941 tcgccatggc agctccgccg aatgcgtaag cgtggttgat cttgtctttt gtgtcatgtc
    24001 caacgatgtc gacatacgta tcacgaggaa tgctgacaat cgttgtctgt ttgtcttcag
    24061 gactgactgt ggcaaccatc atcgtatctg atcttccttg atcgacccga cctaaatctc
    24121 ccgtatcaat ccccatcaat agaacagaga aagattcttg tttgtccaga tcaactggtt
    24181 ttgttcgttc tccttgggtt cgttccactg attcgtaagt tttttcaata gaatgtgaga
    24241 gatctagata taattttgct cctactccta cgattgctaa tactaatacg acaagaattg
    24301 ctaaaataat tagaaatatc tttttccctc ttgatcttct tcttcgtttt gccatagttt
    24361 cctccgtttg ctagccttgc ttgaattctc gcttattaat agctcgtatt gctatagccc
    24421 atttgctgag cgactgtttc tgcttttgac gcgtatgcgg ctcttatttt ttcattccgg
    24481 atctgttcga tgagactgag tgcggtcaaa tattgatcgt aagtagcagt agctgttact
    24541 tgaccgtctt tcagcatcgt atcgaatagc tgatctagtt gcgtgacttg cgcgatctga
    24601 gtatcagcga atcctagata ttgcataaca accgttttcc aaggactatc tttaaaaaag
    24661 ctcatatttt cacgtacacg agcgacatct gcacttgtca ccttttcttt gatgacgaca
    24721 tcgtctacag cttgctgcca gtttgataca tttttagtaa ataaatcgtt gacagctgtc
    24781 tggatcttca gttttgattc tgcatcctct aactgcgtta agactgcttt cttttcttct
    24841 tggatcgcag cagcttcttt aggtaattct gattccttga tgtcataatc atctgccgaa
    24901 agtttgatag aagatagttt atgtgacaaa tttgaaactg tttcttctgt tatttcagga
    24961 tttaggaaaa ttttttcttt tgtactgtac agcttatcta cttcttttga taaagaggtc
    25021 acggtgtctt tttgattggt gatggcagat tctgcgtaat tgatccgttg atgatgttgc
    25081 cgctgattat tgaaatggta tccaaacaag caaatcacaa tagcgcctgt gcctaccgcc
    25141 acagtagcca ataacttgac gaacggcttt tccatagatt cactcctaaa tattgatgat
    25201 agataaataa agatgtgatt cattcccatc agaatgagcg ctttttattt taaa
//
LOCUS       DACDAF010000033        24934 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.033, whole genome shotgun sequence.
ACCESSION   DACDAF010000033 DACDAF010000000
VERSION     DACDAF010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.033"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(369..1487)
                     /locus_tag="IVZ69_001288"
     CDS             complement(369..1487)
                     /locus_tag="IVZ69_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183386.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1958..3265
                     /locus_tag="IVZ69_001289"
     CDS             1958..3265
                     /locus_tag="IVZ69_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAP8183387.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            3384..4583
                     /locus_tag="IVZ69_001290"
     CDS             3384..4583
                     /locus_tag="IVZ69_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HAP8183388.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(4610..5878)
                     /locus_tag="IVZ69_001291"
     CDS             complement(4610..5878)
                     /locus_tag="IVZ69_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HAP8183389.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
     gene            complement(6041..6687)
                     /locus_tag="IVZ69_001292"
                     /pseudo
     CDS             complement(6041..6687)
                     /locus_tag="IVZ69_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="FusB/FusC family EF-G-binding protein"
     gene            complement(7095..7598)
                     /locus_tag="IVZ69_001293"
     CDS             complement(7095..7598)
                     /locus_tag="IVZ69_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP8183390.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(7721..8485)
                     /locus_tag="IVZ69_001294"
     CDS             complement(7721..8485)
                     /locus_tag="IVZ69_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HAP8183391.1"
                     /translation="MKEIQSVKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLAEVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSSTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            8592..8867
                     /locus_tag="IVZ69_001295"
     CDS             8592..8867
                     /locus_tag="IVZ69_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HAP8183392.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            9583..10536
                     /gene="yidC"
                     /locus_tag="IVZ69_001296"
     CDS             9583..10536
                     /gene="yidC"
                     /locus_tag="IVZ69_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HAP8183393.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGGAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVIMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAAKPADNKQATKQIKQPKNSTNNKGRNAGRQQKRK"
     gene            10658..11867
                     /locus_tag="IVZ69_001297"
                     /pseudo
     CDS             10658..11867
                     /locus_tag="IVZ69_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017466553.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
     gene            complement(12177..12398)
                     /locus_tag="IVZ69_001298"
     CDS             complement(12177..12398)
                     /locus_tag="IVZ69_001298"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP8183394.1"
                     /translation="MFKNYTINQKILPLDMEQYISETDVAFAVNALVEEKIKVDLYVS
                     SKFTNVKVVGADLFVVNVRKQKVSETDKF"
     gene            complement(12559..13080)
                     /gene="tnpA"
                     /locus_tag="IVZ69_001299"
                     /pseudo
     CDS             complement(12559..13080)
                     /gene="tnpA"
                     /locus_tag="IVZ69_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631987.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13171..13537)
                     /locus_tag="IVZ69_001300"
                     /pseudo
     CDS             complement(13171..13537)
                     /locus_tag="IVZ69_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
     gene            complement(13551..13836)
                     /locus_tag="IVZ69_001301"
                     /pseudo
     CDS             complement(13551..13836)
                     /locus_tag="IVZ69_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
     gene            complement(13842..14036)
                     /locus_tag="IVZ69_001302"
     CDS             complement(13842..14036)
                     /locus_tag="IVZ69_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183395.1"
                     /translation="MAETRPKGYPKLKEYTPSRFMLSECHYDKARADRAVNFIGQLRH
                     TKGKWAGNRFWLLPWQEQII"
     gene            complement(14036..14512)
                     /locus_tag="IVZ69_001303"
                     /pseudo
     CDS             complement(14036..14512)
                     /locus_tag="IVZ69_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004070864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
     gene            complement(14980..15333)
                     /locus_tag="IVZ69_001304"
     CDS             complement(14980..15333)
                     /locus_tag="IVZ69_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183396.1"
                     /translation="MAMSEKAKKYLKEIKGAKTIPELKDVEIAIKRDGILAWAEFTKL
                     NEAVEEKKVALRKKKQETSLQEILFWAYKKESDKLLKMMDEGADKDAIQMQVQRYDSI
                     GQIIAEADLEDEYEV"
     gene            complement(15461..16000)
                     /locus_tag="IVZ69_001305"
     CDS             complement(15461..16000)
                     /locus_tag="IVZ69_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183397.1"
                     /translation="MQLLLYRIGDSTKIRFLINVRFRVIYSTVLPKGIPQRQKWMIHM
                     EEIMQMILGNAKFQLGQVVSTPAVLETFNPLQTANGIPEALSNLWFRQEISIAEIEDA
                     VLDAKNGKELANSLNRIKLFRKFTLDRELDGMVRLKGTDVWKNISYLKVYTATPPKKP
                     TPPRFQSNGWSLFFSHKSA"
     gene            16030..16221
                     /locus_tag="IVZ69_001306"
     CDS             16030..16221
                     /locus_tag="IVZ69_001306"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183398.1"
                     /translation="MIIRDDHIYTCDSCHYSFPADEQPERCPDCEKTATRLDTEIETE
                     DYYRVRAEIKAEIKALNAG"
     gene            complement(16263..17129)
                     /locus_tag="IVZ69_001307"
     CDS             complement(16263..17129)
                     /locus_tag="IVZ69_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP8183399.1"
                     /translation="MEELFSNALKSVKSNRVLYTASFFARSSLLYLQEIGQLTALKAH
                     TSRRTGLSSYLCFLVEVGSGTLEYKGQKYTLQVGDMVFIDCLKPYVHESSEDDLWTLR
                     WCHFNGIGMTEVYKKYLERGGQPVFKTSKTDKYADLLRSLHMVAEGQEYVRDMKINVL
                     LSELLMHLMEDSWNPDKVPNFSTKKMELQNIKQYLDDHYTEKITLDQLSAEFFINKQY
                     LAKIFRETYGTTVVGYLNQKRITQAKHLLRFTNLSMEEIATKIGITDANYFSRTFFKV
                     EGVRPSEFRKMW"
     gene            complement(17153..18805)
                     /locus_tag="IVZ69_001308"
     CDS             complement(17153..18805)
                     /locus_tag="IVZ69_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HAP8183400.1"
                     /translation="MNYKVEYERWLNHANADIIEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLADYLNKNYEAASVVVGYDSRIKSDVFAKTAADIF
                     AANGIQVHLWPELLPVPTVSFATRYLKADAGVMITASHNPSKYNGYKVYGADGCQITT
                     EAATAILAEIEKLDIFADVKMDGDASKIASIQSEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEIKEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKSAHGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PADPVMVKTIVTMDLGERIASNYGVRTIDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLLDKLNEIYTKYGYCLNTLHSF
                     EFDGAAGFTKMQEIMVEFHKGLDIIGGKKVIETLDYSKGLNGLPKSDVLKFMLEDNCS
                     VVVRPSGTEPKLKTYISVSAENKEAAEAMEAIMAAELAEMFE"
     gene            complement(18810..19712)
                     /locus_tag="IVZ69_001309"
     CDS             complement(18810..19712)
                     /locus_tag="IVZ69_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HAP8183401.1"
                     /translation="MMNLQKELRCLLLRKLGMLYAPGWTELCCVWSEYQGMTLTEVLQ
                     EHPEFLGTHPQTKGELPILIKFIDAKKDLSVQVHPTDEYAIEKENGQLGKTEMWYVLD
                     ASLIYGLQKITEEAVIREAIAQGTVERYLQKVPVKKNDVFFIEAGTIHAIGAGALIAE
                     IQENSNLTYRLYDYDRVDKNGKKRELHVDKALEVANLKGLSEPKQPLRVLKYRAGVAA
                     ELLCRCKHFEVSRMIVNTERRQTVHYRADSISFRVLLCVNGCGTVRFDNESLDIYKGD
                     CLFVPADSTEISIHGSIQFLDVRG"
     gene            complement(19796..21109)
                     /locus_tag="IVZ69_001310"
     CDS             complement(19796..21109)
                     /locus_tag="IVZ69_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAP8183402.1"
                     /translation="MNIVLLSGGSGKRLWPLSNDIRSKQFIKIFKTEDGYESMVQRVY
                     RQIKKVDNDATVTIATSKTQVSAIHNQLGEDVGVSVEPCRRDTFPAIALATAYLVDVM
                     GIDPEESVVVCPVDPYVEDDYFEALKSLSDQADKGEANLVLMGIEPTYPSEKYGYIIP
                     ESAEQTAFVNTFKEKPSEAVAKEYIAQGALWNGGVFVYKLKYVMERAHQLIDFVDYQD
                     LFNKYDTLTKISFDYAVVEHEDKIQVQRFAGMWKDLGTWNTLTEGMEESIIGKGVMNE
                     NCDGVHILNELDVPVLAMGLHDVVICASREGILVSDKEQSSYIKPFVDKFEQQIMFAE
                     KSWGSYKVMDVEAESMTIKVTLNASHSMNYHSHKNRDEVWVVLAGTGKTIVDGYEQVV
                     KAGDVITMSAGCRHTIMADTELKLIEVQLGKDINVKDKQKFELEY"
     gene            complement(21177..22121)
                     /locus_tag="IVZ69_001311"
     CDS             complement(21177..22121)
                     /locus_tag="IVZ69_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019150212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HAP8183403.1"
                     /translation="MMEKDAKIYVAGHRGMAGSAIVRELNRQDYNNIITRTHKELDLC
                     RQDAVEAFFAQEKPDYVFLAAAKVGGIIANQNALADFMYENMILEMNVINSAWENGCK
                     KLQFLGSSCIYPRMAPQPMPESCLLTSELEKTNEAYALAKISGLKYCEFLNKQYGTDY
                     ISVMPTNLYGPNDNYHPTHSHVLPALIRRFHEAKEAGLPTVTCWGDGSPLREFLYVDD
                     LANLCVFLMNNYSGDETVNAGTGKELSIKELTEMVAKVIGYEGEILWDTSKPNGTPRK
                     LLDVSKATKLGWTYKTELEDGIRLSYEDFLNNPMRAER"
     gene            complement(22158..23171)
                     /locus_tag="IVZ69_001312"
     CDS             complement(22158..23171)
                     /locus_tag="IVZ69_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183404.1"
                     /translation="MATLCRCEAKITLVCGANHLDFAKRNLEQELPKELIDRVRYRPI
                     NTDIGLINREGTLLVDTGKLTEICEYFLAKVPSLAKTEAEWLKREAVSAVLCDMPIWA
                     MDACDMAGVPFLYVGNFTWTELYREFLPEHIWKEYAKRYGKIQHTMLYALNNEEMLEF
                     LQNSEKTPTSVVARPIHNDEVQRIKSQHEKPPVFVALGMSARFKQPIDVSHAPYDFIT
                     TLGVPLVGENVTVISNSTPNTQDYIAAADYVITKAGWGTVAECILAQRPMALFARDTV
                     LEDRTTICKLQKLGLAISVTPENLHRVERVIEDLKQLDTSNFDTFYDAASEIADKLIS
                     LMQ"
     gene            complement(23251..24297)
                     /gene="gmd"
                     /locus_tag="IVZ69_001313"
     CDS             complement(23251..24297)
                     /gene="gmd"
                     /locus_tag="IVZ69_001313"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HAP8183405.1"
                     /translation="MKKALITGITGQDGSYLADFLLEKGYEVHGITRRASISNTARID
                     HLMGKITLHDGDLSDSSSLIRIISIVQPDEIYNLAAQSHVQVSFDVPEYSGDVDALGV
                     MRILEACRILGLTKKTKIYQASTSELYGKVEEVPQRETTPFHPYSPYAVAKQYGFWIT
                     KEYREAYGMFAVNGILFNHESERRGENFVTRKITLAAGRIAEGLQDHLELGNMDSLRD
                     WGYAKDYVECMWMILQHETPEDFVIATGEQHTVRDFTEKAFAANGMTIRWEGTGIDEK
                     GYDVETGKMLVCVNPQWFRPTDVDNLWGDPTKAKTVLGWNPQKTSYEELVNIMAKHDR
                     ELAKREAAMKNAVK"
     gene            complement(24569..>24934)
                     /locus_tag="IVZ69_001314"
     CDS             complement(24569..>24934)
                     /locus_tag="IVZ69_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP8183406.1"
                     /translation="QPLTEVEIFHTDRGKEFDNQAIDELSTTFDINRSLSHKGCPFDN
                     AVAESTYKSLKVEFVYQYTFETLQQLDLELFDYVNWWNRLRLHGTLGYETPVGYRNQR
                     LAQRILDNELGCANASEAV"
BASE COUNT         7092 a         5643 c         4750 g         7449 t
ORIGIN      
        1 ttttttaaac ggtgttccag aagtagcttc ttcggaaata agccgaaatt tcacaaaaat
       61 ttgagaaata atttttgtca atctcttctt atttcttgaa gctgaccact tctgtcacaa
      121 cctcttcctt aaacggtgtt caaaagcttg catctgcggt aataagccca ccaaacaaaa
      181 aatatgaaga gctatttttg cttgctgttc ttattacttg atgcagaaca gctttttcac
      241 aacctctcat acacggtgtt taatcagctg accttcggta ttagctcaaa aaacggaaaa
      301 atatgtgaaa ctatttttcc gtttgtttct ctaatactca ggtcaaaaca ctgatttcac
      361 aacctctttt aataacgaag aatcgctgtc agactctttt catctggcgc atctttttga
      421 tccaaaataa acactttccc gccattaatg atcacatcat ctgctaatgc attcaacact
      481 tgacgccgat catattctgt ttcaggatct tcaccgaaac catcagctaa gtttgacgta
      541 gcgataaata aatgtgacac ttttccttct ttcgcagctg gaacgatatc aactaactga
      601 tcgatgaatt tcttatctaa gagtttattg tattcttttg attcttgagc tgcgagttca
      661 cttgacagct tcttcgcccc ttcttcgata tctctaaagg atagctgcgc aggagaagca
      721 gaaatcgcaa cgtctgcaca ataataggga tttttagcaa tttttttgaa catcgtctga
      781 ttttctggta atgcaaataa ataaatcggc cattgttcag gattttcgaa agaatccttc
      841 aagtacgtat caacagcttg gtaatagttg acccaatcga tctctacttc ttcatctttt
      901 ggatttacgc catggaaagt tactccatct cgggctccgc ctcctccatt agaagagaag
      961 ttcaaaccgc cacctgtcag ttcagatccc aatgcagtaa cgacatcaac cggtgcccct
     1021 tctggtagag atacttcttt tacttgtttg ttgctgacct catacaattt catggagtcg
     1081 cggttcaatc ccaataaata ataagaatag ttgaactgcc catttttgat aatagccagt
     1141 aaataaggaa gatcacttac atagtattga tcgtctaccg ggatactcaa acgatggata
     1201 taggtctggt cagcagttat aatgaccgct acactcgtag ttgcactacg ccaaaacgaa
     1261 ggatctccta acaaattttc aattttttct tggaacgggg accagtcatg ttcggaatat
     1321 tttttctcaa aacgtttctt tgcttctttc gcaaaatttt tgaatttgat ctgatctttt
     1381 tccacatctt gatgggcgac atgcgtattc agcatgatcg tgacgaatgg tcctttagcg
     1441 ccttctgaag tcaattgtgt caataattct ttatcctttt ttgccataaa cgtacccctc
     1501 ctaaaaaaat cattcctttg tttctatcta aagtctacca caacactatt tttccataca
     1561 ataaaacgta tctaaaaaaa taaaacggtt tctacggttt taaatttagc tattttttta
     1621 agttatcttc ataatttcct caattattta gccccagtct tcaactattc ttcatgaaat
     1681 gctgataaac taagaaaaag aataaaagag gtggatctta tgcatttgat tatgattttc
     1741 agtttattaa gtattatcag tttatttgct ttcagcgctt cccgcttatt agatgcggaa
     1801 acacagccta ttcctgtaaa agtacgtaaa aacgaccgct aaacttccat aacgcgcgtt
     1861 cttatcctaa agttttttca gaaacattga aactctctcc cctctctgat aaaattttaa
     1921 tttgtagcga aacaaattaa ttacaaggag atcggatatg tccataaaaa aaacacgtct
     1981 agtcctatta ttggctagtc tcattctttg ccttgcttct tttctaccag ctgttgctgt
     2041 gcaagctgaa gatacgttca aagtaaatgc aaaagcagct tttgctgtag atgcgcaaag
     2101 cggtaagatt ctttatgatc aagatggaga aaaaaccatg gggatcgctt caatcacaaa
     2161 aatcatcggt ctttacatcg tccttgatca agtaaaagaa ggaaaactgt catggggtga
     2221 taaagtttcg atttcagatt atgcagaaaa tttgagtatc accccagatt tatcgaatgt
     2281 tcctttgcat aaagaaaaca cctacactgt caaagaatta ttcgactctg caatcatcca
     2341 gtcagccaat gcttcaatgg tggccttggc agaaaaaatc tctggcagcg aagctaaatt
     2401 cactgaacga atgaaagaac aattgaaaga ttggggaatc aaagatgcaa caatcgttaa
     2461 tgcatcagga ttgaacaact cttatcttgg cgaaaaccga ccagaaggca ctggagaaaa
     2521 cgacgaaaat caaatgtctg ctcaagatgt ggccatcgtt gcccgccatt tgatcttgga
     2581 tttcccagaa atactggatg tatcaagtac tacgacccaa atgtttggcg aaaatacgca
     2641 atcaccagtg gaaatggtca actggaactg gatgctccca ggattcgtta attacaagga
     2701 aggcgtggac ggattaaaaa ctggtacgac tgagcttgca ggtgcttgtt tcgttggtac
     2761 gatcactaaa aacgatcaac ggatcatcac tgtcgtattg aatgcggacg gccatgcgga
     2821 aaacccgagt gcccgcttca atgaaacaga ccgtttgatg gactactgct atgacaattg
     2881 gtcagaaaaa gagctcggaa aagctaacgc aagtattcct agtctaaaaa ccattgatgt
     2941 aaaagacgga aaagaatcaa cagttcctgt tgtgcttaaa agccctgtaa aagtatgggt
     3001 acgaaacgat atggatactg gcaaattaac gatcacgcca acacttgaca agaagcaagt
     3061 cactgacaat gagatccaag cacctatgga taaaggtaca aaaatcggta ccgctacgat
     3121 caccttggca gacgataaat taggctattt agaagacaac aatgcaccat caacagagat
     3181 cattacggat aaaacagtgg aaaaagcgaa tatattcgtg attggctggc gacgcgtcgc
     3241 agaatttttc ggcaacttgt tttaattgaa caataagaaa aacatctttc catcggaaag
     3301 atgttttttt gctttttcta gtttaaataa cagctttttt catctatttt cgttatactg
     3361 tataagaaaa aggagttgaa tttatgaatc taaccagaga tctgatcttt ttagttctct
     3421 atcttattgg ggtattctct atcgtttatt ggcgaaaaca gaagaaggat ccttccttgt
     3481 tcttttacgg cagtacgtgg acatttacgg taatcttaac ttattttgtc gtgttggaaa
     3541 ttttttattc gaccttttat tttttgattc cattgttgtt ctttagtatc tttgcttttt
     3601 cttatttcac agaaaaacga aggctactga atggtctttt attcaatgtt ttactcatca
     3661 gtttcggcat ctacttgttt gtcttgctgt atgaaacgca aaatattttt cttggcggac
     3721 tgatcgcctt gatcacgatt ccattgctac ttgtcctttt atttggtatt tatggattga
     3781 ttgtttttct tttttggaac ggggtcacag ttttacgtag agaatcgcat tcattagcta
     3841 atcttttaac gttgatacta gccatttttc ttacactgtt tcttgttttt gactttttct
     3901 tgttaaaata tttgccgcaa tggataaatg ctttgttttt ctgcgttccc ctgatcttga
     3961 tctatctatt tatcgtattc tacaactttt tgactgtctc attcttgtat cagttcaacc
     4021 ggcctcgata caatcaagac ttcatcgttg tgttaggcgc tggattgatc aatggagaaa
     4081 cagtttctcc tcttctagcc aagcgaatca ataaggcaat tgctttttat cgggctcaaa
     4141 gccgtgctac attaaatccg cccatcttat tgatgtctgg cgggcaagga gcagacgaaa
     4201 aagtaccaga ggccattgcg atgaaacaat atgccatgga acaaggaatc cctgaaagag
     4261 acattcttgt cgaaaccaat tcgacaacca ctttggaaaa catgctctat tcaaaggaaa
     4321 tcatggatca gcaaatgaaa gggccatacc gcgcgatctt tagttccaac aattaccaca
     4381 tttttagagc cggtctttat gcgcggcaag ccaaattgaa agcaaatggt attggtgcaa
     4441 aaacagcttt ctactacttg cctaatgcgt ttttaagaga atacctcgcc atcttgatga
     4501 tgaacaaaaa aagacatatg atcatttgcg gattgctttt cgcaggctcc gcattcttat
     4561 cgctgattac tttacttttc taaaaaaaca aggtgtgaca aaacatatgt cacaccttgt
     4621 ttttttcttt cattctctta actattggca aaaagagtat cccttttttg accgctactt
     4681 gctgagcaga ataaataccg ctgttgcctg aacacataaa gctgatcaag cagatcataa
     4741 agaagtatac tgccgcttgt gaaccgaaca attcgatccc catcacaaag caggcaatcg
     4801 gtgtatttgt cgcaccagaa aatactccga taaagcccaa tcctgcaaga aaaggaacag
     4861 aaacatggag caaaggcgct agtgctgcac caagcgttgc accaatttca aacaatggtg
     4921 tcacttctcc cccttgatat cccgcgccta aagacaaaac tgtgaagaat aacttcccaa
     4981 taaaatcata gacatgtgcc tgtccattaa atgattcttg aagtaacgga agactcaatc
     5041 cgagataacg ttgtgtttgc aaaatcaatg ctgctgccac aactacagct ccacctatcg
     5101 tatttcgaca aacaggatga ggaatccatt gtgcatatcg cgcttttaaa aagacgatcg
     5161 aacggctgaa tacccaacca atcaaaccaa aagcaatccc agcaacaaaa actttgaaga
     5221 acagcaacat actccattca ggaatcacac ccatttggta atgtagatga gaaacaccat
     5281 agctttctgt catgaaattt gcaaacagtg cagcaaagaa gctagggaag atcgcttctg
     5341 ttcggacttt cccgattgcc aacacttcta atccaaataa tgttccagct aaaggtgtgc
     5401 caaatacaga actaaaaccc gcactgattc cactgataat caagatttcc cgttctgatt
     5461 tatccaatcg gaacaaacgt gccgtattat ctgctaacgc tccccccatt tggactgctg
     5521 ttccttcacg gccaacagat cccccaaata aatgggtagt tatggttcca aacagtgtaa
     5581 gtggaataag ccgcaacggg attttttctt ctccaccatt tccttgatcg atcactaagt
     5641 tgtttccacg actagaaagt ccgccgtgat acgcatagag ataagcaaaa agcgcaccac
     5701 taactggtag tagacaaagg agccaaggat gtgatagtcg gatatctgtc acaactgtca
     5761 ggctatttaa gaaaaaagca gacaagctcc ccatgaatat accgagaatc gctgtgatca
     5821 ccagccactt cagcatatac actaaaatgc gtactggact cggtaattgt ttttccataa
     5881 aaaattcctc ctcaataaaa aaacgcctac taaagaaagg ggctgtcccc agactttagt
     5941 aggcgtcatt agctatcttt cgttagcatt taaaggcgaa caccatcacc tattcacttc
     6001 cattaaaaga tagcatattt ttctgtaaaa aacaataaaa ttatcgttct ttctttacac
     6061 gttcagcaaa ttcatagaaa ggagccaatt tcgttaactg ttgattacat tggtcactat
     6121 catgacaaat ataattcccc tttttcgtat acgtgccatc agaacctgct ttcgttgtag
     6181 aaagaaaaag cgaaacattc gatgttttct gacagattgc acagattccc ttatttatcg
     6241 ttggtgataa agtaccgcta atccctttta atttttcatc ttcgtaatag accatgaatt
     6301 ttttctgcgt acctggatca ttccagccga tgtacgtatg ttcttgcaag tcgatttcat
     6361 tccaagctgg ttgtttgagt tttttcactt ttcggaataa tttctcgatt tgtggtttgc
     6421 taggctgcat aaacggctga acgatttgct tcagctcctc caatgctctt tctgcttgcg
     6481 cttttgtcag ttttacgtct aaaactgtcg ttaaaaatgt atcgattctg gcagttcgtg
     6541 atctaatatg tctcgaatct tttcagctgc tagtgcctga actgtttgta ccgtttttgg
     6601 atcattgaca gatgagtacg catttaataa ctgttctact tctcttatta taaaaaaata
     6661 ttggtatggt tttattgttt gttccatgat tttaaagtcc tttcttctaa ccaaagtgca
     6721 tactttgtag aaaaaagtga tcttctgcaa agtatgtgtt acctgaagat cctggactct
     6781 tttaaataag atacgttttg catcttatca tcaccccctt taatgcttat tattctatgt
     6841 acatgattca ttcgataaat aaaagtaaac cgtatcttga acagatagtc aactgcaaac
     6901 agaaaaaagg actgtgacaa aagtcgtgtc aaagtccctt gtttcgaatg aatggtgttc
     6961 aaaagcttgc atctgcggta ataagccgaa acttcacaaa aatttgagaa gtaattttcg
     7021 taaattcctt cttatttctt gaagctgacc acttctgtca caacctcaat atggtctatt
     7081 attggtttta cctgttaaat cgaggattct ttcccaaagt aacgttgcca tctcttacgc
     7141 atacttgcag acatgggctg agccgcttct ttgactgcgc agtatttgtc cacgaatgtc
     7201 acaatatatc cttctttata cttaggcggt gcgatcgttg caccccacat gtgcttcaaa
     7261 atgatatctc gctcaagatc cgacaaatcg gtgatttttt ctgcattctt tacagcaatt
     7321 cttggatgga tatacgcatg tgtcccctcg tcaaatttcg tcgtacgcca atcatagtag
     7381 aacagatcat gcaaaagtcc agcacgcgct gttgctttag cattgccacc ccattttttt
     7441 gcgagcagat aactatagta agaaacactg atggaatgct ccaaacgagt ggaatgaaca
     7501 tgctgtgtgt aattcgctaa ttttttcact gcttctgttt ctaaaagatc ttgtacataa
     7561 gacatatatt cttcgtcttc acgccatttt tctgtcataa ttatcgattt gccacctttt
     7621 tgaatttcat tttcttctga aattgatcta agtataccac cagtgttcgg attattctag
     7681 tcgctctaga taaaatagct aaagcttaat agttccttaa tcataaagaa aaatgataaa
     7741 gaacgatccc tgctgcgact ccgacattca atgattccgc atttcctttc attgggatat
     7801 atacgttctg atcagtcgaa gacaagattt cctgacttac tccctgacct tcgtttccca
     7861 tgattatagc gaaatcctct gttttttcta ctttgtctaa tgcatgtgct tcttcattta
     7921 attctgtacc gtacaccgta aaccctttgc ctttcattac agggatcact tctgccaaat
     7981 ctttttgtaa cacaggcaaa tgataattgc ttccctgcat gcttcgcagc acctttgtac
     8041 tataaatatc tgccgttcct ttacctaata aaacaccagc cataccaaac gcatctgccg
     8101 tacggatcat cgttcccaca tttccaggat cctgtacatt atctagtaaa agccagcctc
     8161 ctgaaaaatc tggcgtatct tcagatgtta acgtcatcac tgctaagatc ccttgcggtg
     8221 taggtagatc tgacatagcg gtcatgacct catctgaaac tagaaaagta gaaatctctt
     8281 tgtttacagc cagccagtct ccccattctt tcatacctct ctgtgtcaca aaaagttctt
     8341 ttatttctgc atcagacgac gcagcttctt cgatcagatg gaacccttcc aaaagatatt
     8401 ctgccttttc ttctctgtat ttctttttat gtagtttttt taattctttg attcttggat
     8461 tttttactga ttggatctct ttcacattcc tcacctcaac tgattatatc atggaatagg
     8521 tgcttgagct tgtttcatcc taaaaaaatc ggtatcattg atttataaaa caggaaagaa
     8581 aggtgacgaa catgcgcaaa gttaaaatga atgtccaagg acgtgtccag ggcgtgggat
     8641 ttcgctatat gaccaagatg gttgctgatc agttaggcgt gaccggaacg gtaaaaaacg
     8701 aagacgacgg ctcagtcaca atcgaagcaa tcggaaatga cgacatcatc caaaaattta
     8761 tcgaagaagt caagaagtct ccgagcccaa gtggacgagt gcagtatgtg gatgtccaag
     8821 aagatccgat gattgaggaa cgaaagaaat ttgatgtggt gggataaggt tgtttttgaa
     8881 gcgctttgcc tcgagtatta aggagaaaca ttttccaaat agcttctcat attttgaaat
     8941 gtaatgactt aataccgaga ggcagctgat aaaacaccgt caataaggtt gtgaaaaagc
     9001 tggtctgcat caagcattaa ggactggttg tgaaaaatag ctctccatat ttttcaacag
     9061 gctggactta atgccgtaga tgcaagcttt tgaacatcgt cgataaggtt gcgaaaaagc
     9121 tgatctgcat caagcattaa ggactggttg tgaaaaagtc gcttagtttt gagtattaag
     9181 gaaaattttg tgaaaatggc tttccacatt tttgcataaa tttgacttaa taccaagaaa
     9241 ctgacttttg aacatcgtcg ataaggttgt ttttgaggca ctttgcctca agtattaaag
     9301 acaggtagta aaaaagctga tctataactt gcaataaatt tgcttaaccc atattttcca
     9361 gacagaacaa aaaagttttt agttttttaa ataagaaaga aacacttgga atcactcttt
     9421 tctttctaag tatttctttc ttgatttttt gtcttttttc aaaatttttc gctacgaaaa
     9481 agaacgaata tttatatgaa atttctatga agttgattga attccatgcg cttttttagt
     9541 atagttaagt ttgtgtaaaa attatagaag aggaagtatt ctatgaataa atggaaaaac
     9601 tggttattgg gatccggact tgtcagtatc ctgctctttt tatctggctg tgtgcggatg
     9661 gattcaaacg gaaaccctga cacttcagga atcgtttatc gagtactcgt ccatcctatg
     9721 ggccaagcga ttacatatct agttgagaat ttcaattggt cttacggctg ggcagttatt
     9781 gcaatgactg tgatcgttcg tatcatcatc ttgccactag gtatcagtca atcgaaaaaa
     9841 acaatgatcc aatctgaaaa aatgcaagcg ttaaaaccac aagttgaagc agcacaacaa
     9901 aagctaaaag ctgcaacaac acgtgaagaa caaatggcag cacaagcaga aatgcagcaa
     9961 gtatatcgcg aaaatggatt gagtatgacc ggcggaatcg gctgtctgcc tctattgatc
    10021 caaatgccga tcttctctgc cttgtatttt acggctcgct acacagaagg tatccgtgaa
    10081 tcatcttttt acggcatcga tctaggctca ccaagtatgg tgcttgtggc catcgcaggg
    10141 ggcgcttatc tgcttcaagg atatatttca acaatcggta ttcctgaaga acagaaaaag
    10201 acgatgcgta cgatgctgat cgtctctcct gctatgatcg tcttcatgtc gatcagtgcg
    10261 ccagccggtg ttacacttta ctgggtagtc ggtggtgtgt tcagctgtct gcaaacattc
    10321 atcacaaacg ttataatgaa accgcgtttg aaagcacaag tggcagaaga gttgaaacaa
    10381 aacccgccaa aacaagtcgt tactccaaga aaagacgtga cagaatcagc agcaaagcca
    10441 gctgacaaca aacaagcaac aaaacaaatc aaacaaccaa aaaacagtac aaacaacaaa
    10501 ggccgcaacg caggaaggca gcagaagcgg aaataaaaat atatgacaaa aaactgtaga
    10561 caaataaaaa aatttctttg ttctacagtt tttttgttac aattaaagaa aacgttcgca
    10621 tttcgaggag gaatgtataa tgatgtccaa ataatcaatg tatagtcgaa tggaagaaga
    10681 caaaatttcg ctagatgcac ttgttcctaa aaatcattta gtccgtaaaa ttgacaaatt
    10741 attgtcattt gattttattt atctcattgt tgaatcaact tactcgacca ttggtcgccc
    10801 tagcgttgat cctgtcgtct tagtaaaatt agtattcatt caatatttat ttggaatttg
    10861 ttcgatgcgt cagaccatta aataagttga aacaaaccta gcttatcgtt ggtttcttgg
    10921 gcttagttta attgataaag ttcctcattt ttcaactttt ggtaaaaact atgcacggcg
    10981 tttcagagaa accgatttgt ttgaacagat atttatcatt attctcgaat aagcagttga
    11041 tgctagattt attcatgaag aaattttgta tatggattca actcatatta aagcgaatgc
    11101 gaacaaacgt atttttacaa gagatatggc acataaagaa gccattttat accaaaaaca
    11161 attagaagaa gaaatcaatg aggcaagaat tgccgaaggc aaacgtcctt ttggttcaat
    11221 cattcgtcag gaggtggtcg aaagaaaatt tagcatcgca gatccagaaa gtggttatta
    11281 tgtaaaaaca gaacgagaaa aacagtttgc ttattctgct cataccgttg gtgatgaaaa
    11341 tggttttgta ttagatgtca tgattacgcc tggaaatcta catgatagcc gaatgctcgt
    11401 gccacaaatc gaacgcgtta aatcacgtta tggtgtagct gctaatgctg cgtacaaaac
    11461 accttggaac gtcaagtatt taatcgaacg aaaactacga cccattctcc cttatatcag
    11521 tttcgcacaa ctactcgaga tggctataaa aaatatgtat ctaaatcttt tatttgtgaa
    11581 agttgtccat tattgaaaaa ttgtacagaa agccaaaaac accaaaaaga aatacatcga
    11641 catatttggg aagactactt agatgaagca gaacatttac gccatacggt gtacaatcgt
    11701 gaaaaatata aaaaaagaaa agaaacgatt gaacgcattt ttgcagacgc aaaggaaaaa
    11761 catggaatgc gctacaccaa gtatcgaggc ttggaaaaaa tcaggtgcat acaatgcttg
    11821 tttttgtcgc aatgaatctg aaaaaattag ctacttggca gtgggagcat atgtcgttat
    11881 atcttttatt atacaaaaat agacaaaagt atcagtctac actcttagta aagaggaaac
    11941 tgatgctttt gtctacagtc ttagagagtg ggacaatagt tttttcttct ttacgtcttt
    12001 tcctctccat gtattttcct aattttctta atttaacgcc atgagtgcca agccaatgtc
    12061 aatcttggct ccttgtttcc ttcataagtg gaaatccgtt tccgatagat cgaaccttct
    12121 ttttcctcta aaagtttttt tacattctgc tttgaaataa cgccatgtat tattcactaa
    12181 aatttgtcgg tttcgctcac tttttgcttt cgtacattga ctacgaacag gtcagcaccg
    12241 accactttca cattcgtaaa ttttgaagac acgtataaat ccacttttat cttttcttcg
    12301 actaaagcgt tgaccgcaaa agcgacatct gtttcagaaa tatattgttc catatctaat
    12361 ggtaaaattt tttggttgat ggtataattt ttaaacataa agcactcgct tcctttctga
    12421 ttgggtttgg tcactttaat cctacaggga tgagtgcttt ttgtgtacct taaaatcagt
    12481 aaatatccat ccgtgaaaac gggtggcttt ttaacagccc tagaagggct caccactcac
    12541 agccctatct ctctttaact atttaaatgg atctacatac tcttgtttac ttatactgtc
    12601 tctaattcga tcatctgctt cttgttctca aatatatatt tcaattgttt tttgatttaa
    12661 cccaaccgta ctcacgtagt atcctttggt ccaaaagctt ttattcccat acttatattt
    12721 caaatttgca tgtttttcat ggattaaggt tgcacttcgt ccttttaagt agcccataaa
    12781 actagaaata ctaatctttg gcggtattct tactaacata tgaatgtgat caggcattgc
    12841 atgagcttca atgatttcaa catctttcct ctcacacaat tttcttaata tctggccaat
    12901 acttactctt aactttccat aaatcacttt tcgtcgatac ttcggggtaa agactatgtg
    12961 atacttacaa tcccatctcg tatgtgctaa acttttatcg ctaaagctat ttcgtccacg
    13021 cgtagaaacg cgcgtttttt tgtttcgtac gctacgccaa cgaaactgac taaagtcaat
    13081 aaaaaaagtg gggcaataat cagatttttt tctgactatt gtcccactct ctttttatta
    13141 ctcttcatct tctactattc cactaattaa ttagttgaca gatacaatgc tttcacatcc
    13201 tgcacgaaca aactcgggct ctgaaccaat cacttgcgag ttgataaatt caatgaccat
    13261 aggaagatta atccgacata aagtttaatc tgttgtcctt ccattatcag tttagaaatg
    13321 atattagtag gtgtaccgcc taaaagatcg catagtacca caaaatcatt taacgaatct
    13381 atgacagtaa gagcttttgt ctgtatgttt cagtgccatc ttctggtaat aaaggtaacg
    13441 tgtagatatt ctcttgaggt cccataatca tttttgtact ttttttcaat tcctcacaaa
    13501 attttccgtg actaatcaat atcaattttc tactcatttt tggctctccc ttatttcgaa
    13561 atcacacaca atgcagataa agccacacac aagtaatacg ataaaaatcg ctcgagttgg
    13621 gtcatatttt tctttcctaa caaccaataa acacctcgac gatcccagcg agtaagattt
    13681 tagataatat catatcgata tagttttgca tattcaatgt cacatcgcca atcgttggta
    13741 ccataaaaat ttaatatcaa tcattgttgc aactaatgct cctaccatga acactcttaa
    13801 taaagtcgct acgtccgtta atacagttaa gcgagattac actagatgat ctgttcctgc
    13861 caaggcaaga gccagaagcg gttgcctgcc catttgcctt tggtgtgtcg gagctgtccg
    13921 ataaagttca ccgcccgatc cgctctggct ttgtcgtagt gacattccga aagcatgaat
    13981 cggcttggtg tgtattcctt taatttggga tagccctttg gtctggtttc tgccatcagc
    14041 taccacctcc caacagagcc tccatcgcat cttctgctcc gacaccaccg ccatcaccgg
    14101 caatgatacg gcttctggac gaaggcgtca gaccgaactg ctcggaaaat cggttcataa
    14161 ttttcagata ggtctgggca ataaacacct gtggtacctg ctgccaatag ccggataggg
    14221 ttttcacgat gataccgtgc tgggtaatga attcctcggc ttccttccag cgggcgtagg
    14281 cttggcacta accggcaaag gcagccatat ccacatctgt caagattccg atggcctcca
    14341 tctgctttgc cagacgcttc cattccttct ttgcctctgg ttccagccac ttcggacagg
    14401 tcggtgcctt cttttccggc gttgactctt ttgcattgag tgggcgattg cccggatttc
    14461 cctccagctt cttcatggct gtcggggttg attttcttcc tctggttgcc acagtcgtca
    14521 cctcccttca atgtatttct gccagtagac agagaacaga gccaagtcga aacctgactc
    14581 tcttctctat ctgctaactt gtatttcagt ccactcttct gatgaatcgc acccgcagga
    14641 ttttcaagat gccgcaggca aattccaaga agtttctgac cgcatcataa ccatcgtagc
    14701 cgtgtagcca catccttcca cctcgccgcc gtcctcgtcg ctgatataaa tgattctgta
    14761 ttcgctcatc tgttgttttc tccagtcttt tgtttttttg tagtacatat atcactctaa
    14821 aagtgattat tatcaagtcg tttgaaagcc ataatgtaca caatcattcg actggttttt
    14881 ggttcataat tgaccgccaa agtgagcaaa agaaagggac ctctgtctgt ttcagaagtc
    14941 cctttcggta tttggttctt agtggttcag gctgtattct caaacctcat actcatcttc
    15001 gaggtctgcc tctgcaatga tctggccgat gctgtcgtaa cgctggacct gcatctggat
    15061 ggcatccttg tctgctccct cgtccatcat cttcagcagc ttgtctgatt cctttttgta
    15121 ggcccagaaa aggatctcct gaaggctggt ctcctgcttt ttcttgcgaa gggcgacctt
    15181 cttctcttcc accgcctcgt tcaacttggt gaactctgcc caagcaagga taccgtctcg
    15241 cttgattgcg atctccacat ccttcagctc cgggatggtc tttgcaccct tgatctcctt
    15301 caaatatttc tttgcctttt cgctcattgc cattagcgtt tcctccttgt ttttgggatt
    15361 ttcccctttg gttgtgtgta tattgccata gtctctcgac tatatcaagt caatccacag
    15421 gcatatacta cacaatcatt tggagctgta tttgtataca ttatgccgat ttatgagaga
    15481 agaaaaggct ccagccgttc gactggaacc ttgggggggt cggtttctta ggcggcgtgg
    15541 cggtgtagac cttgaggtag ctgatgttct tccagacgtc cgtgcccttc agtctgacca
    15601 tgccgtccag ctctcggtcg agggtgaact tgcggaaaag cttgatgcgg ttgaggctgt
    15661 ttgctagctc cttgccgttc ttggcatcca gaactgcgtc ctcgatctcc gcaatactaa
    15721 tttcctgtct aaaccaaagg ttgctcaagg cttcgggaat gccgtttgcg gtctgcaggg
    15781 ggttgaaagt ttccaataca gcaggggtcg aaaccacctg tccgagctgg aattttgcgt
    15841 tccctaaaat catctgcata atttcttcca tgtgaatcat ccatttctgc cgttgtggta
    15901 ttccctttgg cagtacagta ctatatatca ctctgaatcg tacatttatc aagaagcgga
    15961 tttttgtgga atcaccaatt cgatataata gtaattgcat gaaaaatcta agcactggat
    16021 tggtaggtga tgattatacg tgacgatcac atttacacct gtgattcctg ccactacagc
    16081 ttccctgccg acgaacagcc agagcgttgt cctgactgcg aaaagacagc aactcggctg
    16141 gataccgaaa tcgaaactga agattactat cgtgttcgtg ctgaaatcaa agctgagatt
    16201 aaagctttga atgcgggtta acgacaggta ctgaccggcg gctcaacacc gccggctttt
    16261 tattaccaca tcttgcggaa ttcgctggga cgaacacctt ccaccttgaa aaaagttctg
    16321 gaaaaatagt ttgcatctgt tatgccaatt tttgttgcaa tctcttccat acttagattt
    16381 gtaaagcgta gcaagtgctt ggcctgtgtg attcgtttct gattcagata accgacaaca
    16441 gttgtaccgt aagtttcacg aaaaatctta gctaagtact gtttattgat aaaaaactct
    16501 gcactcaact gatccagcgt aatcttctcc gtgtaatggt catccagata ttgttttatg
    16561 ttctgcaatt ccattttttt tgtagagaaa ttcggcactt tgtcaggatt ccaagaatct
    16621 tccatcaaat gcatcagcag ttcactgagt agaacattga ttttcatatc ccggacatac
    16681 tcctgtccct ctgccaccat atgaaggctc ctcagcaagt cagcatactt atctgttttt
    16741 gatgttttaa agaccggttg accacctcgt tcaaggtatt ttttgtagac ttccgtcata
    16801 ccaatgccat taaaatggca ccaccgcaaa gtccacaaat catcttctga tgactcatgg
    16861 acatacggct tcaaacagtc aataaacacc atatctccta cttgaagcgt atatttctgc
    16921 cccttatact ccaatgtgcc tgaaccaact tctaccagga aacaaaggta agatgacaat
    16981 cctgtacgcc tagatgtatg tgccttcaga gcagtcagct gtccaatttc ctgcaaatac
    17041 aaaagagagg atcttgcaaa gaacgatgcc gtgtacagca cacgatttga cttcaccgat
    17101 ttcaaagcgt tagaaaacag ttcctccatt acaagatttc tcctttcttt tcttactcga
    17161 acatttccgc cagttcagca gccataatag cttccatagc ttcggcggct tccttgttct
    17221 ctgcgctgac gctgatatag gtcttcagct tcggctcagt accagaagga cgaaccacaa
    17281 cagagcagtt atcttccagc ataaacttca aaacatcaga cttcggcaga ccattcaggc
    17341 ccttactgta gtctaaagtt tcaataacct tcttaccacc aattatatcg agacccttgt
    17401 ggaattcaac cataatttcc tgcatcttgg taaaacctgc cgcaccgtca aactcgaagg
    17461 aatgcagggt gttcaaacaa tagccatact ttgtataaat ctcgttcagc ttatccagca
    17521 ggctgatacc ctgagtcttg tagtaagaga acatttcaca gattagataa gcagcgttaa
    17581 caccgtcctt gtcacggaca tagctaccgg acagatagcc gtaagattcc tcaaagccga
    17641 agatatagct gtcaacctta ccagcctttt ccaacatacc aatctgctca ccgataaact
    17701 taaagccggt cagcacatcg atggtacgaa caccatagtt ggatgcgata cgttcaccca
    17761 aatccatggt gacgatggtc ttgaccatca cagggtcagc aggcattttt ccatgcttaa
    17821 ttctctgaga acagatgtag tccagaagta gcagaccagt ctcattacca gacaacagaa
    17881 catagtcacc atgtgcgctc ttaactgcga taccaacacg gtcgcagtca gggtcagtgg
    17941 ccaacagcag atccgcattg tacttcttgg catactccat acccagagac atagcttcct
    18001 taatttcagg gttcggataa ggacaagttg ggaaattacc gtccggcaga cgctgttctt
    18061 ccacaacggt cacattgctg tatcccatct ctgccagggt gcgggtaaca ggcaccagac
    18121 cggtaccatt cagaggagaa tacacgatag caacattctt gtccacttct tcgccaaaca
    18181 ggacggactg ccccttcact tcttcgatga aagcagtcag aacttccgac tgaatggatg
    18241 caatcttaga agcatcgcca tccatcttta catcagcaaa gatgtccagc ttttcgattt
    18301 ctgccagaat tgcagtagca gcctcggtag taatctgaca gccgtctgca ccgtatacct
    18361 tgtagccgtt atatttagaa gggttatgag atgccgtaat cataacaccg gcatctgcct
    18421 tcagataacg agtcgcaaaa gatactgtag gaacaggaag cagttctggc cacaagtgca
    18481 cctgaatacc atttgcagca aagatgtctg cggcagtctt tgcaaacaca tcagatttga
    18541 tacgggaatc atagccaacc accacggaag cggcttcata gttcttattc agatagtctg
    18601 ccagaccttg gcttgcctta cctacggtgt gtacgttcat gcgattagtg cctgcaccga
    18661 tggtaccacg cagaccacca gtaccgaaag acaaattttt atagaaagag tcctcaatgt
    18721 ccttctcaga ataggaacgc agttcttcta taatatctgc attggcatga ttcagccaac
    18781 gctcatattc tactttataa ttcatattat tatcctctca catccagaaa ctgaatcgac
    18841 ccgtgaatgc tgatttcagt agaatcggcc ggcacaaaaa ggcagtcccc cttatagatg
    18901 tccaacgatt cattatcaaa tcgaacggta ccacagccat tgacacacag caacacacgg
    18961 aagctgattg aatccgcacg atagtgtacc gtctgtcttc tctcagtgtt gacaatcata
    19021 cgagagacct cgaaatgctt gcatctgcaa agcaattccg cagctacacc agcacgatat
    19081 tttagaacac gaagcggctg tttcggttct gacaaccctt tcaagttcgc tacttccagc
    19141 gctttgtcta catgaagttc tctcttttta ccatttttgt caacacggtc ataatcgtag
    19201 agacgataag tcagattgga attttcctga atttctgcaa ttagtgcacc cgcaccaatc
    19261 gcatgaatcg ttcccgcctc aataaagaac acatcattct ttttgaccgg aaccttctga
    19321 agataacgct caacagttcc ctgagcaatc gcttcacgga tcacagcttc ttctgttatt
    19381 ttctgcagcc catagattaa gctggcatcc agtacatacc acatctctgt ctttccaagc
    19441 tgcccgtttt ctttttcaat tgcatattca tctgtgggat gtacctgaac agacaaatcc
    19501 tttttcgcat caatgaattt gatcaggatc ggcaattctc ctttggtctg cggatgcgtt
    19561 cccagaaact ctgggtgttc ttgcaacacc tccgtcaagg tcatcccctg atactctgac
    19621 cagacacaac aaagctcggt ccatccgggt gcgtagagca ttccaagttt ccgcaagagg
    19681 agacatctca attccttttg caaattcatc attcaggcgg ttccccccca cagataatcc
    19741 tttgcggaag gcttcaataa aaacggtttc tgtataacga gccctcctcc gttttttaat
    19801 actctaactc aaatttctgt ttatctttaa cattgatatc cttgccaagc tgtacttcaa
    19861 tcagcttcag ctcagtatct gccataatgg tatgccgaca gccagcactc atggtgatca
    19921 catcgccagc cttaacaacc tgctcatatc catccacgat ggtcttacca gtaccggcca
    19981 gaaccaccca cacctcgtca cggttcttgt ggctgtgata attcatggag tgactagcat
    20041 tcagagtaac cttaatggtc atgctctctg cttctacatc cataacctta taactacccc
    20101 aagacttctc tgcgaacatg atctgctgct cgaacttgtc aacgaaaggc ttaatatagc
    20161 tggactgttc cttatcggaa accagaatac cttcccgaga tgcacagatg accacatcat
    20221 gcagacccat agccaacaca ggaacatcca gttcgttcag gatgtgtacg ccatcgcaat
    20281 tctcattcat aacaccttta ccgataatgg attcctccat accttcggtc agagtattcc
    20341 aagtccccag atccttccac ataccagcaa aacgctgtac ctgaatcttg tcctcatgct
    20401 caacaacggc atagtcgaag gaaatcttag tcagagtatc gtatttgttg aacagatcct
    20461 gataatctac aaagtcaatc agctgatgtg cacgctccat gacatacttc agcttgtaga
    20521 caaacacacc accgttccac agtgcaccct gtgcgatata ttcctttgcc acagcctcag
    20581 aaggtttttc cttgaaggta tttacgaaag cagtctgctc tgcgctctca ggaatgatgt
    20641 agccgtactt ctcggaagga taagtcggtt caatacccat gagcaccaga ttagcttcgc
    20701 ctttgtcagc ctgatcggac agagatttca gggcctcaaa atagtcatct tctacgtaag
    20761 ggtcaaccgg gcaaacaact acggactctt ctggatcaat gcccatcaca tctaccagat
    20821 aagcggtagc caatgcgatt gccgggaagg tatcgcggcg acaaggctct acagatacac
    20881 ccacatcctc accaagttgg ttatggatag cagaaacctg tgtcttagag gttgcaatcg
    20941 taacagttgc gtcgttatct accttcttaa tctggcggta gacacgctga accatggatt
    21001 catatccatc ttcagttttg aaaatcttaa tgaactgctt ggaacggatg tcattagaca
    21061 gcggccaaag gcgcttacca gaaccgccag acagtaaaac aatattcata atgatctctc
    21121 ctttttataa gaaagaggct gctgcaatcc tcaaaaatca cagcaacctc ggtaaattag
    21181 cgttcagcac gcatcgggtt attcaggaag tcctcgtagg acagacggat gccatcttcc
    21241 aactcagtct tatatgtcca tcccagcttg gttgccttgg aaacatccag cagcttacga
    21301 ggtgtaccgt tcggcttgct ggtatcccac agaatctcgc cttcgtaacc aataaccttt
    21361 gctaccatct cggtcagttc cttgatagac agttccttgc cagtacctgc attaacagtc
    21421 tcgtcaccgc tatagttatt catcaggaac acacacaggt ttgccagatc gtcaacatat
    21481 aggaattcgc gcagaggaga accatcaccc cagcaggtaa cagtaggcag acctgcttcc
    21541 ttagcctcat ggaagcgacg aatcaaagcg gggagcacat gactgtgagt aggatgatag
    21601 ttgtcgttag gtccatacag gttagtaggc ataacagaga tatagtcagt accgtactgc
    21661 ttgtttagaa actcacagta cttcaggcca gaaatctttg ccagtgcata agcctcgttg
    21721 gtcttttcca gctcacttgt cagcagacag ctttccggca tcggctgcgg tgccatacgc
    21781 ggatagatac aggaagaacc gaggaactgt aacttcttac agccattctc ccatgcggag
    21841 ttgatgacgt tcatttccag aatcatgttt tcatacatga agtctgccag agcgttctgg
    21901 tttgcgataa taccgccaac ctttgcagca gcgagaaata cataatccgg cttttcctgt
    21961 gcgaaaaatg cttcaacagc gtcctgacgg cacaggtcaa gctccttatg ggtgcgggtg
    22021 ataatattgt tgtagtcctg acggttcagc tcgcgcacga ttgcggaacc agccatgcca
    22081 cgatgaccgg ctacgtagat ttttgcgtct ttttccatca taataatgct tgctcctttc
    22141 taaatttaga gcatctctca ttgcatgaga gaaatcaatt tgtctgcgat ttcgctcgca
    22201 gcatcataaa atgtatcaaa atttgaggtg tctagctgtt tgaggtcctc aatcacccgc
    22261 tctacgcggt ggaggttttc cggtgtgacg gaaattgcca gacccagttt ttgcaattta
    22321 caaatagttg ttctatcttc caaaactgta tcgcgggcga acagtgccat cggacgctgt
    22381 gcgagaatac actccgcaac agttccccat ccagcctttg taataacgta atctgccgcc
    22441 gctatatagt cctgtgtatt gggggtgctg ttagaaataa cggttacgtt ttctcccaca
    22501 agcggaacac ctagcgttgt aatgaaatca tacggcgcgt gactgacatc aatcggctgt
    22561 ttgaaccgcg cggacatacc gagtgcgaca aatacaggcg gtttttcatg ctgtgattta
    22621 atgcgttgca cttcgtcgtt atgaatcgga cgcgccacaa cggaagtcgg tgttttttcg
    22681 ctgttttgga gaaattccaa catttcttcg ttatttagcg cataaagcat ggtgtgctga
    22741 attttaccgt aacgcttggc atattctttc caaatatgtt cgggtaaaaa ttcgcgatac
    22801 agctctgtcc aagtgaagtt tcctacatac aggaaaggta ctcctgccat atcgcaggca
    22861 tccattgccc agattggcat atcgcaaagc actgcgctga cagcttctcg cttgagccat
    22921 tcggcttctg tctttgccaa agaaggaacc tttgccaaaa aatattcaca gatctcggtc
    22981 agcttacccg tgtccaccag tagggtgccc tcacggttaa tcagaccgat atctgtgttt
    23041 attggacgat agcgcacgcg gtctatcagc tctttgggca gttcctgctc caaattgcgc
    23101 tttgcaaaat ccagatgatt tgcgccgcaa accagtgtaa tcttcgcttc gcatcggcag
    23161 agtgttgcca taataatggg cagattccgc gcgatatgtc cgaagccgtg actggaaaga
    23221 tagaaacaga tatgtttatt caatgtcagc ttacttgact gcgttcttca ttgcagcttc
    23281 gcgctttgcc aattcacggt catgctttgc catgatgtta accagttcct cgtaagaggt
    23341 cttctgcgga ttccaaccga gaacggtctt tgccttagtc gggtcgcccc acaggttgtc
    23401 aacgtcagtc ggacggaacc actgtggatt tacacaaacg agcatcttgc cggtttcaac
    23461 atcgtagccc ttttcatcaa tgccagtgcc ttcccaacga atggtcatgc catttgctgc
    23521 gaatgccttc tcggtgaagt cacgaacagt gtgctgctcg ccggtagcga tcacgaagtc
    23581 ctcgggagtc tcatgctgga gaatcatcca catgcactca acatagtcct ttgcatagcc
    23641 ccagtcacgc agggagtcca tgttgcccag ttccagatgg tcctgcaggc cttctgcaat
    23701 gcggccggca gcgagggtga tcttacgggt gacgaaattc tcaccgcgac gttcggattc
    23761 atggttgaac agaataccgt tgacagcgaa catgccataa gcttcacgat attccttagt
    23821 gatccagaag ccatactgct ttgcaacagc ataagggctg taaggatgaa acggagtggt
    23881 ttcacgctga ggaacttctt caaccttgcc atacagctca gaagtagatg cctgataaat
    23941 cttagtcttc ttcgtcaggc ccagaatacg gcaagcttcc agaatacgca taacgcccaa
    24001 agcatcaaca tcgccggagt actcaggaac atcaaaagaa acctgaacat ggctctgtgc
    24061 agcgaggtta tagatttcat caggctgaac aatgctgatg atacgaatca gagaagatga
    24121 gtcggacagg tcaccgtcat gaagggtgat cttgcccatc aaatggtcaa tgcgagcggt
    24181 attggaaata gaagcacggc gagtgatacc gtgaacttcg tagcccttct ctagcaggaa
    24241 atctgccaga taggaaccgt cctgaccagt aataccagta atcagcgctt ttttcatgat
    24301 acattatcct ttcctatgta agtgataagg ccatataaat ggctcgtaat ttctaatact
    24361 tttcaagaat acacgataat tttcgatatt tcatagaaca atctacgcac gcattagcac
    24421 aatattagtt tttcgtgaat tggaatggca acagtttttt tgacaaattt tataaggtgc
    24481 agaacttctt tccgtatgct attccgattg tccttgacaa tgagcctcct cggatgtgac
    24541 gatcttcggc aggagctaac agttaaagtt agactgcctc gctagcgtta gcacatccga
    24601 gctcattatc aaggattcgc tgcgccaatc tctggttacg gtaaccaacc ggtgtctcgt
    24661 agccaagtgt accgtgcaac cgaaggcggt tccaccaatt gacatagtca aataactcca
    24721 aatccaattg ttgtaaggtt tcaaatgtgt attgatagac aaattctact ttcaacgact
    24781 tataagttga ttcagctacg gcattatcaa aaggacagcc tttatgactc aatgatcgat
    24841 tgatgtcaaa agttgttgat aattcatcaa tagcttggtt atcaaactct tttccacgat
    24901 cagtatgaaa aatctcaacc tctgtcagag gttg
//
LOCUS       DACDAF010000034        24747 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.034, whole genome shotgun sequence.
ACCESSION   DACDAF010000034 DACDAF010000000
VERSION     DACDAF010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.034"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(57..173)
                     /locus_tag="IVZ69_001315"
     CDS             complement(57..173)
                     /locus_tag="IVZ69_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAP8183407.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            complement(418..1332)
                     /locus_tag="IVZ69_001316"
     CDS             complement(418..1332)
                     /locus_tag="IVZ69_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP8183408.1"
                     /translation="MMKFGKNQNTEKQTPKEKKPRVYKVNPRKKVVIVLWVLLGLSFS
                     FAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWELNDKSIDNRIEN
                     LKAYLTEELQALNVDTVRKDIPVSSSVKGFQIWTVEADGDNQFDVTYSVDQLITEGEN
                     TKTVHSAYIVSVYVDSTGNMVLIKNPTITSIPKKSDYKPKAIESEGTVDSITTNEINE
                     FLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIYNRKDNQVTVSLTVEY
                     IDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            complement(1347..2348)
                     /locus_tag="IVZ69_001317"
     CDS             complement(1347..2348)
                     /locus_tag="IVZ69_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAP8183409.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDGGFSNIHYGGV
                     DVSAEVLAHKPMVEKVAKEYGIEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLGVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGDEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKFEGWKYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTRHIPLLEAKA
                     GDLVFFHSTYNAGSYITHIGIYLGDNRMFHAGDPIGYADLTSSYWQQHLVGAGRIKQ"
     gene            complement(2345..4528)
                     /locus_tag="IVZ69_001318"
     CDS             complement(2345..4528)
                     /locus_tag="IVZ69_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HAP8183410.1"
                     /translation="MKPSILNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVTPSGLSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHALMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNMTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRM
                     MRKPRMLMHAHMHRLQRKLGRSVTALGAGSAIASATGKKGQSGSGSSASTQADHSRPN
                     GQEKSTLGKRIGQTIGTVADTKDRMVDTAGNLKEQVKDLPTNARYAVYQGKSKVTDNV
                     HDLTRSISQTKADKASGRKKQQEQRRKTIAERRSEMEQVKQKKQPASSVHERPATKQE
                     QSHDGQTSRQTTVQASYRESQQAKQERPTVKSDSSSLKTERQSNTVQERTVQKPVTST
                     APTDRASQRSITKERQSTVQRVPLQNTKSRPPIKTATIKKGSKKP"
     gene            complement(4531..6978)
                     /locus_tag="IVZ69_001319"
     CDS             complement(4531..6978)
                     /locus_tag="IVZ69_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP8183411.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSILSAQERSKNEVTGKLKTVAYDKIDQQTDALISM
                     IGENQVDYRFFIGFKLLLNDQEFSMKSLTVEAKNAFTDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYPLSKKKLEH
                     ETLIKTYDLIKPTRCLVEEKQRYLKIQQEDETAYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLAGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVNLTSDEKNKGLLDPYVIMKNTKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSDGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            complement(6962..7354)
                     /locus_tag="IVZ69_001320"
     CDS             complement(6962..7354)
                     /locus_tag="IVZ69_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP8183412.1"
                     /translation="MKKIRSYTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAV
                     MILGNLPPLSMIEGAFLKYFGIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRRKLTY
                     AGKKVTLGRNQPQEAITAVRSEFYGISN"
     gene            complement(7441..7938)
                     /locus_tag="IVZ69_001321"
     CDS             complement(7441..7938)
                     /locus_tag="IVZ69_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP8183413.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSISELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMSDVARYYIEETGALGEVPASLQNYIDYESYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            complement(8055..8279)
                     /locus_tag="IVZ69_001322"
     CDS             complement(8055..8279)
                     /locus_tag="IVZ69_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002570387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183414.1"
                     /translation="MSGTYLSIYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFL
                     IIAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            complement(8383..10293)
                     /gene="ltrA"
                     /locus_tag="IVZ69_001323"
     CDS             complement(8383..10293)
                     /gene="ltrA"
                     /locus_tag="IVZ69_001323"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP8183415.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            complement(11077..12282)
                     /locus_tag="IVZ69_001324"
     CDS             complement(11077..12282)
                     /locus_tag="IVZ69_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HAP8183416.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            complement(12305..12458)
                     /locus_tag="IVZ69_001325"
                     /pseudo
     CDS             complement(12305..12458)
                     /locus_tag="IVZ69_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
     gene            complement(12461..13846)
                     /locus_tag="IVZ69_001326"
     CDS             complement(12461..13846)
                     /locus_tag="IVZ69_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP8183417.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            complement(13875..14261)
                     /locus_tag="IVZ69_001327"
     CDS             complement(13875..14261)
                     /locus_tag="IVZ69_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP8183418.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            complement(14277..14591)
                     /locus_tag="IVZ69_001328"
     CDS             complement(14277..14591)
                     /locus_tag="IVZ69_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HAP8183419.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            complement(14944..15423)
                     /gene="rlmH"
                     /locus_tag="IVZ69_001329"
     CDS             complement(14944..15423)
                     /gene="rlmH"
                     /locus_tag="IVZ69_001329"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HAP8183420.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYGLAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            15851..17140
                     /locus_tag="IVZ69_001330"
     CDS             15851..17140
                     /locus_tag="IVZ69_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HAP8183421.1"
                     /translation="MDRKNVTPKMKKNKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVMMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
     gene            complement(17179..17784)
                     /locus_tag="IVZ69_001331"
     CDS             complement(17179..17784)
                     /locus_tag="IVZ69_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HAP8183422.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVASYGMICSARELHLPNAPEKKGILVLPEDAVVGEVFPK"
     gene            complement(17980..18444)
                     /locus_tag="IVZ69_001332"
     CDS             complement(17980..18444)
                     /locus_tag="IVZ69_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP8183423.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKALEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKQMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYAIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            complement(18466..18786)
                     /locus_tag="IVZ69_001333"
     CDS             complement(18466..18786)
                     /locus_tag="IVZ69_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP8183424.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VIKG"
     gene            complement(18929..20008)
                     /gene="pepA"
                     /locus_tag="IVZ69_001334"
     CDS             complement(18929..20008)
                     /gene="pepA"
                     /locus_tag="IVZ69_001334"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HAP8183425.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            20208..20558
                     /locus_tag="IVZ69_001335"
     CDS             20208..20558
                     /locus_tag="IVZ69_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP8183426.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKTSFLKEGAIEGAWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLDISRKKGAID"
     gene            20743..21696
                     /locus_tag="IVZ69_001336"
     CDS             20743..21696
                     /locus_tag="IVZ69_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HAP8183427.1"
                     /translation="MESREKIAVLIPCYNEEATISTVIEDFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAAHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVKNTITYLYKTKIRDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMCKDYKPLLFFGIWTIFFFLFGLVMGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYQNKEMK"
     gene            21709..23496
                     /locus_tag="IVZ69_001337"
     CDS             21709..23496
                     /locus_tag="IVZ69_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183428.1"
                     /translation="MHKKKENLFPTFFATLFASGFAFFTSYGLGTLNPTVIIGLAMVL
                     LLAFKQYGIELFSIKNKVAAIARLFFSAAFALTLSIGRQIQFQYVSANYTKTTIADGS
                     IFYFLVYFSIFVYSFLFLQSIYLSMPKLETFFTAQNTQAFSSRKYFLFFTVFLVLCWL
                     PYLLALYPGVVLPDSLSSVAQSMGDVPISNHHPVLFTLLVKLFVHDLPTDTINHGVFL
                     FSIFQTLITASAISYSLCWLLKRNIHFFPVLISLCYFAFAPVFPIYALNMQKDTLFSI
                     ACFLFSLAVFDFIFQREKPTILNQIYVIILALLTTYLRNNGIYVVTGTGLICGLIILK
                     QKRYQAFFQVVLGYTVIAGLLIHPLMARYAIPTETAEQLGVPLQQISRTIVMDGDLSK
                     KDKAFMNQLLPIKDYEAYSPSLADSIKWHKNFNNEFLNTHKKEFLSLWARNLPSNIKI
                     YTDAYILETFGFWVPGTKNSYGFLDTRVNTNNYGMKQVDLIEHLTGLSGMKKIIDARD
                     FFGSGTLLWLAIGSALLAIFKKKYRYLLLFLPGMLVFATIMIATPVAFSLRYVFVLAL
                     GLPVYILSPFLLDKREKMKTDIGDTHETI"
     gene            23483..24685
                     /locus_tag="IVZ69_001338"
     CDS             23483..24685
                     /locus_tag="IVZ69_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183429.1"
                     /translation="MKLFKKIFFAFVLLIASYCVLLTITFFIPQHSIESNAEKSLQMV
                     EKEGMYPSINQGNMLGTRLDNFTDHLMIRKTKADPELNSLENAMSMADYPRYWHGYQL
                     FLRPLLLGMSLGSIRMIYAAILFLLIGLTSYFLTKCSDIYLTTALLISLAIGNAATFF
                     FSMQFSNIWILTLLSVLLFLTKPQLSNTNQQLFLYFFVIGSLANFFDLLTTPVISWGI
                     PVIIIYYVTNKYLMDKRSSLSKQVGSFVFTGIFWGLGYGLTWVAKWILSSIILNKNIV
                     KDAINQILFRTEGNDKYPLHRLEMLKSNIRLMYPKVAILLLLITCLVFLYFAYRKRNS
                     WRPFQLLVLFVLAAVTPYIWYNILANHSQIHYWFTYRTQIITSFAILSAFAFLIPPEK
                     SKDELNYF"
BASE COUNT         6992 a         5007 c         4518 g         8230 t
ORIGIN      
        1 gcatcaacat gagctaaaac tccaatatta ataattttca tgtgattttc ctccattcaa
       61 aagcccaaaa gggcataaaa atcccagtga taaatactct tatcactggg atttttatgc
      121 ataaccatag gcatacaaag catacagata ttctccggat actttagaat cacatgataa
      181 aggtattctt aaactgggtg caaaaaacta agccctccta aaaaaggaca tccaattatt
      241 tgttcccact atcaaattga cagtttattt aagaatacct tgccgcatat ttattaactc
      301 cttttaaata gatacttaaa taatagcacg taagagcata tttgtaaagg aatctccaat
      361 tttttatcaa agagagtacg tgattacaaa atagctgtaa taatgtacca atatttgtta
      421 ttctataatc ttccaattac tcccgttctt ttcaagtacc aaatcaaatt gagatacctg
      481 cgttgctttg gtctgctggt cgatatactc cactgtcagc gataccgtga cttgattatc
      541 cttacgattg taaataggat ttaccagttc ttgaaagatg tactcttttc cgattggttt
      601 taatatcccg tcattcacat agtaggaaag ttcactggct gtcgctgtag gatagagctt
      661 gaagaacgtc gttaaaaact cattgatttc attggttgta atggaatcaa ccgtaccctc
      721 actttcaata gcttttggtt tatagtctga tttctttggt atgctagtaa tggtcggatt
      781 cttaatgagg accatatttc cagtactgtc tacatagaca ctcactatat aagcagagtg
      841 gacggtcttt gtattttccc cctctgtaat gagttggtct acactgtagg ttacatcaaa
      901 ttgattgtcg ccatctgctt ctaccgtcca tatctgaaat ccttttacag aagacgatac
      961 aggaatatct ttacgaactg tatcgacatt cagagcttga agttcctctg tcagatatgc
     1021 tttcaggttt tctatgcgat tatcaatgga cttgtcgttt agttcccatg aatagtagac
     1081 tttcgcaaag ttctctacaa aattttccac atgatgagta tcgacatatt ccttttctat
     1141 gatggtggtt tcatgaatgg tatgggtatc aatggctgta aagtgcttga atatcgcaaa
     1201 gctgaaacta agtcctaaaa gtacccatag gacaatcaca acctttttac gaggattgac
     1261 cttatagaca cgaggtttct tttcctttgg tgtctgtttt tctgtattct gattttttcc
     1321 gaatttcatc attgaatcgt cctttcttat tgtttgattc gtcctgctcc cactaaatgc
     1381 tgttgccagt aagagcttgt taagtcggca taaccgatag ggtcgcctgc atgaaacata
     1441 cggttatcgc ctaaataaat cccgatatga gtaatataag agccagcgtt ataggtagaa
     1501 tgaaagaaaa ccaaatcgcc ggcttttgct tccaataatg ggatatgccg ggttacatca
     1561 tattgctgtt gtgctgttcg tggtaagttg attccagctt ttccatacgt ccattgtgtc
     1621 agtccgctac aatcaaaaga ggtagtcggg gaagctccgc catagacata cttccagcct
     1681 tcaaatttca gagcttcgtc catgatggct tgtactgtat catcatcaaa ctctgttgtg
     1741 acaagatact gcgttaccag ttgcacataa aacatattcc cgtaattgta tcgccagccc
     1801 ccattgatag gtatggctat gggattgggg taagacactt tttcgtcacc cgaatactct
     1861 tttgagaaac tttgagccag ttcaaaggta tatttattcc cacgattagc cacatatcct
     1921 aagaaaccac caccataatt gtaggactgg ataaccgatt ctaaatctac accaagcctt
     1981 tcgctactgg ctaataactc actgaaatac ttcacacctt gcttaatgga ttcttctgta
     2041 ctcaatgaat taggtggaag accgagggat tccgaggact gcataacatc ttctgctgta
     2101 ccacccgatt ccacctgtat aatcgcaaga agtatattga cgtattcttc aattccatat
     2161 tctttggcaa ctttttctac cataggctta tgagccagca cttctgcgga aacatccaca
     2221 ccgccatagt gaatgttgga aaaaccgcca tcttgttcat ctgaaaataa aatggcgaca
     2281 aacagaagca gtgagaagac catcaagaat aatcccgaac caccaatcac taaagttttc
     2341 agcttcatgg tttcttactg cctttcttaa tggtggcggt tttgattggt ggtctacttt
     2401 ttgtattttg tagtggtact ctttgaacag tagactgacg ttcttttgtg attgaacgtt
     2461 gtgaagctct atctgttggt gcagttgaag ttactggctt ttgaaccgtt ctttcttgaa
     2521 ctgtattact ttgacgttcc gtttttaaac ttgaagaatc ggacttaact gttggacgct
     2581 cttgtttggc ttgttgagat tccctatagg aagcctgtac agttgtttgc cttgaagtct
     2641 gtccatcatg agattgttct tgcttagtgg ctggtctttc atgaacggaa gaagctggct
     2701 gttttttctg tttgacctgt tccatttcag agcgacgctc cgcaatggtt ttccgtcttt
     2761 gttcctgctg tttcttgcgt ccactggctt tatccgcttt ggtttgagaa atacttctgg
     2821 ttaaatcatg gacattatcc gtcactttag attttccttg atatactgca tatcttgcat
     2881 tggtcggcaa atccttaacc tgttctttca aattaccagc agtatctacc attctgtctt
     2941 tggtatcagc tactgtaccg atggtttgac cgatacgctt tcctagtgtt gatttttcct
     3001 gcccgtttgg tcgagagtga tctgcttgtg tactcgcaga acttcccgaa cccgactgtc
     3061 cttttttacc cgtagcactg gcaatggcag acccagcccc taaagcagtc acggagcgtc
     3121 caagtttccg ctgtagacgg tgcatgtgag cgtgcataag catacgaggt tttctcatca
     3181 tacgacttcc cacactttga gaatcgttac tctgtagaga aaacatactc attaaatcgc
     3241 ccagcttaaa gtagattcct gcaaaggtca caatctgtag aaaagcaatc aaaaagaacg
     3301 gataaccagc cgataaggta tagagcatgg ttgaaatact aaatgctgtc gtaataatca
     3361 atgtgattcc agctcgtgtc aaaatggtat taaagagctt tgttatggct cgttttgaca
     3421 taccatcaaa tgatggaatc atgcttaaaa taaagctcac aggcagaaac atagcataga
     3481 tgataaaaag tacctgcgag aaaatcatga ttcctgttaa taggaataca aatatggaaa
     3541 tcccaatatt gaagacaaat aggaagaaga ctgtacctaa acggttaatc gtctttgtaa
     3601 tcgtcatatt ggtattgctt ctatcttcaa tttcttccgc aacaattttt tctctgtctt
     3661 ccccattgtt ggaatctgga ctggttgaga gcaggctttc cacacggtca ataccaatac
     3721 tttcaatgtc tgaactgtta tattgaagca gtagccacgg ttgctgaacc tgtatggaaa
     3781 ataggctgtc acgtatcaag tccacactgt ccttgccttg actatctgaa tggggcatga
     3841 caatttttgt acccagtgac aaactagcgt tgctgatgtc tgatgaaaag tcattgattt
     3901 ttttaatgta gtcgggagcg taggcaataa aggaagccga taggataaaa accagcacaa
     3961 aattcatgag ggcatgaatt gcctttgtgg tttctctctt tatcagtcct gtataggcaa
     4021 cataaacccc aagaaccaaa atcaagagta aaaggaatcc aacatagaaa ccctctgttg
     4081 atagtccact aggcgtaacc cctgcaaggg tctgcatatt cttgccaatg gaatctgctg
     4141 tagcggaaat gaagtctaag gaataggctt cctgtactaa gtaacccgtc gcattggaaa
     4201 cataaagact gattgtccaa ataaaattgg taatggcata tagtccatac atgacttgtt
     4261 ttccaattcc gtccgaccag ttccacggta gccagcccca gctattatcc acataaaaat
     4321 ccagttgata gttttcaagt gggtatcggc tgtattcatt tgccacattg accgtatcat
     4381 ctaccaagcc cgcagcttga accaccgttc ccagcatggc taaaagaaaa atggcaatca
     4441 caagtgtgaa agccactgtc attgccactt tacctagacg tttcagcgtc cagtttgatt
     4501 ttattctgtt taatattgat ggtttcacat ttacacctct tttcgcacag gtggtctggt
     4561 atcaaaggca tggagcagtt cttcaaatac agggtggaac tgtatcacac cgacacgacc
     4621 atataaatca ctgataaggc attgcccgtt ttccaaatca cgcaatcgct tctgattgtt
     4681 ttcgtcctct gggtctacac caaaaaaggc aagggttttt ttaatctcgt taaggtcagt
     4741 ggaacgaaag gcaaatttta agccgaggtt atttttcagt ttttcatcta agaggtcatc
     4801 tgtattttgg gtcacgaaat ataccccagc gttcatagca cgaccagcac gaaccagctt
     4861 catagatagt gttttccctt gtgccacctg taagaagctc catgcttcgt ctaagtctac
     4921 aatcttgaaa atacttcggt ctgtatggat aaagtccaac gcaaaggtac taatgacaat
     4981 cagcattgct accgatagta actccattgt ggtatattcc tcaaaggaag tttccttgtc
     5041 aggaagtacc aagtcggcaa cctgtataat gttcagttgt ttttcaaggc tgatagactg
     5101 ctctacataa ccatcactaa aaagcagatg ggcaaagtca tagtctgtaa aactttcgat
     5161 atggtcggct atgctggtac ttagtggcgt attctcaacc cgtaattctt caatcacttt
     5221 catcaaccct cgcacttcac tattggttac tgcacgaatg gcttttctaa ggattgggaa
     5281 gcgttcccca tcacgagagg aaatccccgt aaggaatgtc aaaatatcaa tagccagtga
     5341 ttcagaatct ttggtatttt tcataattac ataagggtca agtaagcctt tgtttttctc
     5401 atcagaagtc agattgacga tattgatttc atgggaaatc tctggcaagg tttctttcca
     5461 tctgccacgt tctgcttttg ggtctacaat cactgcttgt gccccataaa gcactgcata
     5521 atagacgata aggttattcg caaaggattt accaccaccc agcgaaccga caaaggcaga
     5581 cgctaacgca ttggttactg aacccttaac cccttgactg gcaagagcag gtttcagata
     5641 gacattgcgt ccagtatcta agctgtagcc aacataaatc ccctcatttt cacccagcat
     5701 ttgagtagca ccaaaaccta aaccagcgag gaaatcagag gtcacgtatt gaatatagtc
     5761 attcatatat cttttgctgg caggtaaaaa ttcttcatgt aagcccagca tatccccaaa
     5821 aggtcgtacc agtttcacgc tcaaatcatc atagaaatct ttcacttcat tacaacgacg
     5881 tttaagttcg tcaaggtcat ttgctgatac ccttacaaca taggacagct tatacataga
     5941 ttccttgctt tggtctaaat tggtttccag ctcgttcaca ctttccagag cttccgccac
     6001 attagagctg gtttcattat cactttgcca agcgtggtta tccaagtctt tcagttcttt
     6061 ctttttattg cggacagtag atagggcttt acgattcgct acaatttcca cattcattga
     6121 cgtatcaatc ggaaaggtaa attgctgttg ctggtagtag aagatttcag aggacgggaa
     6181 gtccagttcg ccgacaatac tgttgatggt aaagtaagct acataggcgg tttcgtcttc
     6241 ctgctggatt ttcaaatatc gctgtttttc ttccaccaga cagcgagtag gcttaatgag
     6301 gtcataggtt ttaatcagtg tttcatgttc cagctttttc tttgatagag gatactcata
     6361 ctcttcatag gcagtgcctg tctgtccgta aaggtgttca atcagatagc cgaagtcatc
     6421 cttatctaat cttcggattt tgaaacgacg ggagatttta ttttctaaaa gcttttccat
     6481 cttctgaaaa cgcaggattt catcattact catactaaca aaatcgccca tcagcttatg
     6541 gttcacatca tagacaaaat cagtaaaagc attttttgct tcaacggtaa gacttttcat
     6601 agaaaactcc tgatcgttga gaagcaactt aaaaccgata aagaaacggt agtccacttg
     6661 attttcgcca atcatggata ttaaagcgtc tgtctgttgg tcgattttgt cataggcaac
     6721 cgttttgagc tttccagtga cttcattttt ggaacgttct tgtgcagaaa gtatgctgga
     6781 ttctgtactg atttgtaaag catgaatctt gccatcacga ttttgtgcga taagctgtct
     6841 gaaagaatca tgtacttgta ttttctgttc cggacttaga aatgagtaat tgtagggaac
     6901 aagctcatag taagcgtaac attccccatc tttattccag accagattgt tttcaatata
     6961 tttaattgga tatgccataa aattcactcc taactgctgt aatggcttct tgtggctggt
     7021 ttctgccaag cgttactttt tttcctgcat aggtcagctt tcgtcgcagt gcataagcaa
     7081 tgacagactt caaaaatcca taaggctttt taccatcaaa ggtttttgta gacataaacc
     7141 atgtgaaagc cacaggaatc ccaaagtatt tgagaaatgc tccctctatc atagaaagag
     7201 ggggcaagtt gccaagtatc ataactgcaa agagtgacac gacaaaccat gtcatttgcg
     7261 taaaggttat gggaaacgga agtctaaagt cattgatgga gtacaacact ttctcaacag
     7321 accagatact ggtatagctt cgtattttct tcatgtaatc aatcctttca taaaaatggg
     7381 gatagtcttt tgactacccc gtaaacaaga aaatctgcca gtaagaatgt accgacagat
     7441 ttaatagacg atttcaaaaa tcccgtgatt ggttgagata aacgttcccg aaaggtctaa
     7501 atcccgacca taggattcat aatcaatata gttttgaaga ctggctggca cttcgcctaa
     7561 agcacccgtt tcttcaatgt agtagcgtgc cacgtcagac atatcatcac aatcggaatg
     7621 aatgataata tcttcttgat gttcgcttag ttcttcaata cttgaaaaat gagtgagcag
     7681 agcagatagc tccgattgta gttcttctgg caactccgat accatttccc ataggcgatt
     7741 gagttcgcta atagaagtgt attcgtcaac cgtaaagggt aactcgtaat catgaatggc
     7801 gtattcctca tattcatcat tcaagccgat tttctctttg acttcctcaa agtcaatggg
     7861 aaaggtaaac cacgcaccga ccaattcgcc ctcattgtat ttgcctaaat tcgcaatata
     7921 gacttgcata tcgtccatat attcacgtcc tttctttgta gagattcaaa aatccctacc
     7981 gcacttcgtt tggtgtacca ttcctttgcg gaacataaga aaaccactta tattccacaa
     8041 aagaacggtt ttatttaagc accaataatg cgattgaata gctctagtaa aatgtctttt
     8101 actccagcag cgttgaagac taagccaacc gcaataatcg caataattaa aaagccaatc
     8161 agtttgctaa actcacgctt gaagccaaga tacaagccaa tcacaacgat tgctaaaagc
     8221 accagtgatt gagcgtttga tagaaaccag ttatatatgg ataggtaagt tcctgatatt
     8281 ataaatatct caaacttttc cccccattca cacggagcgt gcgactttca ccgcactccg
     8341 cgttccatcg tgtttatatt gaaaagtatt tatgtagtag acctatatca agtttaattc
     8401 ttgattgcca gctaatactc tatatttatt tagtcttatg agctggactt tatttagctt
     8461 caatagagct atatattttt gtattgtttc ttctgtttta gcgtgtatta gacggtgtac
     8521 cgcctctttt accaaaataa gatttttata atcgtcattt ccaccagctc cagttggtac
     8581 aatatgatga caatgtattt cattagcttg ttgaaattct tccagagtta tagcacattt
     8641 tccatgttga gcagaaaata gcgaaattcg attgtctgcg tattctattg tgcgattttc
     8701 caaagataat ttcattaact ggtacatcag taatttatca acacttagat tggtgtggat
     8761 aaattttctt ccctctagag tgtagcaatt cgctaaatac acctttgcca ttggttttct
     8821 gtgttggata tatccaacag ggaaaatagg ttcgccctcg ccagcaacat accgaagcat
     8881 tttagattta ccatatcttg ttgcctcctt tgtcgtaagt tgtctgcctg tttttctcaa
     8941 tctgcccctt ttgtttgtac ctaatctgtt agtgaagata gccattacag ctctattcag
     9001 tttcatacaa tccagattta cattcgttgc aatctgataa taattttgca tacctaatac
     9061 cattgaatta taaagtcttg tttcttctaa ttccgttttc ccttttgagg gagaagcaat
     9121 tttctttgcc tgtgatacca gcttgtcttt ttggtttttg aattgtttat cacttatatg
     9181 tgatttaaca actaacttct ttcttctcgg tatcatttta atcttgaaac caagaaagtc
     9241 ggagtatctt tttctaacat ttacaattct tgttttttct tgtgatactt ccaattttaa
     9301 tcgttgttca atccattgag tgattgctat tttggctttt tcagcacttt ccttgtagcg
     9361 gcagaaaact ctaaaatcat ctgcataacg aaccatatac atttccttta actttgtttt
     9421 cttcatttct ttgtaagcgt tgcttttaca tgggctaccg cttttattga tatgaaccac
     9481 atagtttttt gtaacaggat tttcctgcca ttggctttct acccaatggt ctaactcatt
     9541 aagaacaatg tttgctagta gtggggatat tattccccct tgcggagttc ctttctctgg
     9601 atatgttatt gtaccgttag tcattttgat tggagctttt aatatccttt ttaaaatgaa
     9661 tatcaagtgc ttgtcccgta ttcccatagc ccatatctgt tttatcagct tggaatggtt
     9721 cacgttgtca aagaaaccct taatatcaaa ttcaatcaca taatgtagct ggctgatttg
     9781 taggcggtta taggttgctt ttattgcatt ttcaactgac ctattaggtc taaaaccata
     9841 gctgttttca ctaaatttag cttcgcagat tggttctaat acttgtttta tacattgttg
     9901 tataagcctg tcccacatac aaggaatacc tagaggtctg gttttaccat ttggttttgg
     9961 tatttctttt cgcctcactg gcttaggtcg atacccatgt ggactgcctg caacaatgta
    10021 tcttactttt ttgacaactg tttctgctgg caatttgcca atatctttaa ttattgtacc
    10081 gtctgttcct gctgttttac tgcctgcatt tgctttgata tttcgatatg ccagtaatat
    10141 attttctctc gataggataa tatccataag atgagtgaaa atatctccat tcttactttt
    10201 ggcatataaa tcatcaaagg tgttttgcat ttcgtaatat tcagcgtgtc ttaaatcttc
    10261 tacacacaat gtttcatttt tatttttagg cataaggctt cactccttta cttgaaattg
    10321 agtgagcttt tttatcttac tcgtaatcct tattgaaaca acataatact tttctaatat
    10381 atacacgact tgagggcatt cctccattct cattacaaga atttcttagg ttcgccctct
    10441 gcttttcagc attagttcaa ctgcttattg ttcttcgtca gtttattctc ttgatgagaa
    10501 cccaatacct ttcctcgttc cgataatctt atctatacat atatatcctt aggtcactag
    10561 ctataagcct gctggcttga taccgcctgt aacgttatat ggcatttcat aacctatatt
    10621 cttactttgc cacaccagct acgatttctc gtacctttgc atttctacaa agttcaaatt
    10681 tagacccgta cattcgctgt ttcgtcagtt ccttatagaa cattctaacc atagatattt
    10741 tatagacccc cgacctgttg gatacgctac ccacctctgg atagttttcg atagaagata
    10801 tatgttcatc aactattacg gtatctttca gccgtcttta ccgagcttca aacattctga
    10861 gtttcctcat acaatgcttg tcggaggctc agggcaggcg tttcagagcg ttacttcatc
    10921 attccacctg tcagattatc agttctccta ataaccaaac tttttcgttc ttttattagt
    10981 gccttagctt ttcactaagg aacgagtcgc acaaaggttt tgtccaaaat tcataaaaat
    11041 gttctcctct ctatattcaa tgaatttgta tttgagttat ttttttgttg ttatcacgtc
    11101 ctgttctttt actgactgtt gcttcaaaat ctgcttgtgt cggtctgtca gtttcgcatg
    11161 gtcgagaatg tcttttacaa cctgcgtctg gttgatttca tcaagtttaa tcgcaacctt
    11221 taaggtcggg gcaacttgat gagatagcca gttcagcgtc ctttggaagg agtaaggctc
    11281 tggttttgtg gttagtttta atcgttcacg attgttccca ataaaccaag cccattcttc
    11341 attcagtttc caatcagaac gaggtttgga atcgtcttta tctacaaaac ggatataccg
    11401 attgataatt ttaaaggcgg tatgctctgg attgtcatag acgagtaaat cacggactgc
    11461 ataataggca cgctcatttt tcaatcgaat ctcaaaacgg ttttttactt ctgcgtcttc
    11521 aatgggaata tcatttttct tgtactgctc gtagtccttt tcatagatac agaaataaac
    11581 ttcactttgt aatgaaccga tatagagggt gtttcccata cattcctttt cctctttgcg
    11641 taccagttcg ccactgcgat agcttttaaa actgcggaag acggagatac attcttcctg
    11701 ttggcacttt tcagtgagta cagggatatt taaaatccct gtcttatcgt taatggcaag
    11761 gtcaaggcgt ttcatcacac cgccagccac caaaacgtcc ataaagaact cataccagct
    11821 tctttgttgt gccagaagat agctttcaaa ttgtctgcac ccacgacctt tcaattccac
    11881 cagaactcct ttgtccagtt catgggagca aaggacgaat atgtcgccta aagcataatg
    11941 ctctgaataa gaatagaaac catagtcctc atgaagaaaa taggacagtt tcagttgtaa
    12001 gatgttttcg accacctgct gtacgtctgt tgtcggaaag cgaattctta cataatcaaa
    12061 cagcatttca aggggagcgt cgggattgaa gcgttccaga gcttcccaaa gggactgctg
    12121 taaatcctct gatggcttga cttttcctgt ttcaatatcg cttagatact gccttgtaat
    12181 accagtcgca acagctaaac ggttttgaga tagtccataa gccaagcgtt tttcttttaa
    12241 atgctgtaac caagtttgtt cattcagtaa aaatccctcc aatcaaaaag gcgtatgtca
    12301 acttttaaag cccatttgac atacgctgaa attttgtaaa tcccttgtaa ccaaaggatt
    12361 ttctaatgtt tttttgactg tttcctgtcg atttgtaccc ccctgttaga taccgagggg
    12421 ttaagtgctg gcgtggctat tgccacacca gccagcaaga tcagtccaca cctgcgactt
    12481 ccgcttcgca cgtcgcctgc gtggactgtc tgctgttgga taacttttta atttcctcca
    12541 agaaatcata tccttttggt acaaggggag tataaaactc tgatatgaca cttgttccta
    12601 catcaacata gccacgacct ttgattcgct ttaagaagaa atccttttgt acgtcactgc
    12661 caaacatcat gccatagccc atttcagaca tacgacctaa agccactctg aaattaaact
    12721 gatcacggat tccgtcgcct aaatattttg cgtctggacg ttgacaagcc agtattagaa
    12781 agaagccagc ttgacgacct aacatgacaa tctgtttcag cttattcata actgcggtgt
    12841 tttcttttgt tcccagcatt tccatgaaag cgacgtattc atcaaagatt aagaagtgtg
    12901 ccgggagacc taagtaagca taatttttgc cagtcttata gttcttcatc tgcttcattt
    12961 cctcactacg tttcatcatt tcttcataga atgtttcaat gcaagaaagc aagtcttctt
    13021 ttctatagta gacatttgcc atcacagaac ctaagtccgc aaggtcagca tttttcgggt
    13081 caagaatata cagttttgaa tctgtatgaa gcaaggcttc aatcagtgtc agtataaagt
    13141 aagttttacc gccacctgta ccaccagcaa tcaacatatg agggagctta tcatattccc
    13201 accatacgtt tttcattaag cgaagtttac catctttagc ttctacttca tcaatagaaa
    13261 tacgactggc tatggtgtca tagagcaaag tatattccac ataggaatcc tttaactctt
    13321 tatccgtcag ctcacagtac aagccactct ctaatttctt ttccaagtgt aagagttggt
    13381 cttgatattt tcccagcgtg atttccaccc gtatctgtat caagccattt ttaagtcgat
    13441 aatacatttt agggaagtag gttatctttt cctttgtacg accagcacta tctttaaaga
    13501 aaccctctgt tttgacctgt tcagattcat accacttgtt ttcaagtatc atctttgcca
    13561 gtttttgacg gtggtaaagt tgtttaaccg tatcatagcg aacccgtttg aatacaaacg
    13621 ctaccagcaa gcagataaga attgcgacac tgaaactgat aattaaatag ggaatgtcaa
    13681 tcttatctgc ttgtgatagg ttaaaatcct gccagttgat ctgctggatt gtcttcacat
    13741 gaaacagtcc gacaaccagc aggaaaacag gcaggagtga cgctatcgta aaatgaaaga
    13801 ctaaatcttt accagatggg cgaatccttt taccacgctg tttcatgcga aaaagtctcc
    13861 tttctaccta gcgactattt gtcttgtgtc ggttctttct ttgcttgtgg ttgagctttg
    13921 aatgaactag aatcctttgt cagcacaata tcgtctgcct tgatatacca gtcaacatct
    13981 gctccttgat aggtggcagt agcaacggtg tccgcaatgg gattgataag ttccacccgt
    14041 gcgttataat caaactcttt caaaggcacg ctggcaggaa tacttacttg aatcatgcgt
    14101 ccttgtcctt tggattttaa gtcataggta cgttccttga tttcatctga aaccgacccg
    14161 tcttcatttt ggattctcac ttcacgacgt agagcagaga atttcaattc tccaaaagtc
    14221 gtgtctttat ctaatacaat gccatttgct aatctcatca tttttcctct ctttctttat
    14281 tcttttatca tgtcgtcagc atgtaaaagg taatttgtaa aaccacgagt gccgattttg
    14341 tagccctctg cggtaatacg tggattgact aacttcacac gttcctcaaa gccgaaatgt
    14401 ttttcgccag cttcagcagg aagcaccacc acaatatcat ctgctctttg aacatcagaa
    14461 tagagattat agcttcttga taagacagtt agccgtccgt tgattcttcg ctgaacgact
    14521 ttatcctcgc cagcaaattc taaattgccg aatgtttttt ccatgttggg aatcacaaat
    14581 ttaagttcca tatttttacc tatcctttct tttttattgg ctgaatgaat gtttgatggt
    14641 cttaaagagt ggggaacgac cttttgattc ttgatttttt gttttcataa gttcacttcc
    14701 tttcaaaatc gggtaaaaaa atagacacct cattttttga agtgtctacc tattaaatat
    14761 tcaaatttta ttggaagtat ctttatatct tcacttttca aggataaatc gtcgtatcaa
    14821 agctcattca taagtagtaa attagtagta aattgagtgg ttttgacctt gataaagtgt
    14881 gataagtcca gtttttatgc ggataactag atttttatgc tatttttctc ttaaaaaata
    14941 tcattatttg tggtatggag cccccgcgtt gatccggaag gcacggtaga tttgctcgac
    15001 gaggatcagg cgcatcaatt gatgtggata cgtcattttg ccaaaagaga tctgagcatt
    15061 gcttcttttc atgacggctt cgctgagtcc taaagaaccg ccgataacaa aaacaaggtg
    15121 gctttttcct tggataccta attggtcgat ttgtttagca aaagattcgc ttgtgggatt
    15181 tttcccttca attgctaagc catagacgta ttcttgttct ttgattttcg ctaagatccg
    15241 ttctccttct ttttctttta cttgtctcat ttgcgcttcg cttaaattct ccggggcttt
    15301 ttcgtcagga acttcgatca attcgatttt cgcataggca ttcagccgtt tgacatactc
    15361 attgatacct tggatcaagt atttttcttt taattttcct actgaaataa ttttgatatt
    15421 catgttttct ctcctttgat cttcacgctc actttgttta ttataatcaa ttttttcgtc
    15481 tatatgttta ttttgactat ttttgttaaa aagatttccc caacagttat gcacaacatc
    15541 cacaggttta tccacagaaa acagcgttgt tttaccttat ttcatcacat tcattaggca
    15601 aacatacgtt ttataagaat ttatccactt tatacacagg ctgtggatat gttttatccc
    15661 ttatttttcc aatcctatcc gcgtagtttt acacaatatc tgtggaaaaa gaaaatcaaa
    15721 tattttcatc tgaaaacaat gatttttcct aaagtttttc ataaaaagtt caaagtctca
    15781 aagtagacta aagtcaacaa ataagactat actaacagta gataaatgaa tgtaattgga
    15841 ggaggaacac atggatagaa aaaatgtgac accaaagatg aaaaaaaata aaaataatag
    15901 cctctggcgt aagttgggtc tggggcttgt tggagggatc gttggaggac tactgacagc
    15961 tggcattttt tatgcagcga tgggcactgg caacaatagt tctactgcta caagcggcaa
    16021 tcaaaattct gccggtgaaa cagttgtgga aaatgtcaaa gtcaatgtag attctgatat
    16081 caccaaagcg gtagataaag ttcaagacgc tgtcgtttct gttatcaact tacaaagtca
    16141 aaaccaatca agcggttttg gcggattatt cgggcagcaa gaagaaagta gcagctcaga
    16201 tgatagtaat ttggaagctt atagtgaagg aagcggcgta atctacaaaa aagacgggaa
    16261 tactgcttat gtagtcacaa acaatcacgt agtagatgga cagcaaggtt tggaagtcat
    16321 gatgaaagac ggtacgaagg taaaagctga attagttgga acagatgcct attcagattt
    16381 agcggtgttg aagatcaatt cagacaaagt cgaaacggtt gcctcttttg gggactcaag
    16441 tgctttgaag gttggtgaac ctgcgattgc gattggttcc ccattaggat ctgaatatgc
    16501 gaattctgtc acttcaggaa tcatttcttc cttgaaccga caagtaacaa gtacgaatga
    16561 atcgaacgaa acagtcaata tcaatgcgat ccaaacagat gcagcgatca acccgggaaa
    16621 ttctggtggt cctttagtga atatcgaagg acaagttatc ggtatcaact caagtaagat
    16681 cgcaagtact tctgaatcga cttctaatgt aagcgtagaa ggaatgggat ttgccatccc
    16741 aagtaacgat gtagtgaata tcatcaacca actggaaaaa gacggaaaag tgacacgtcc
    16801 agctctaggt atcacaatgg tcgacttatc tgccgtttct actcagcaac aagaacaaat
    16861 cttgaagatt ccttcatctg taactaacgg tgtcatcgtg acaaatgtcc aaacagctac
    16921 accggcagaa aaagctgggt tgaaacaata cgacgtcatt actaagatcg atgacaaaga
    16981 agtttcttct ggtgtagaac ttcaatctgc tttgtataag aaaaaagtgg gagattctgt
    17041 caaaatcact tactatgaag gctcgaaaga aaaaacaact actgttgaat tgacgatcga
    17101 tcaatcggca ttaaaacaaa atcaaaatag tgaaaattaa taaaaaagag gttgtgacaa
    17161 agacttgtca caacctcttt attttggaaa tacttctccg actacggcat cctcaggcaa
    17221 tactaagatt cctttttttt ctggagcatt tggcaaatgc aattcacgag cagaacaaat
    17281 cattccatag ctggctaccc ctcgcaaagt tcctggccag atcatcattc catctggcat
    17341 catggctcct ggttttgcaa cgacaacttt ttgtccagct tcgatatttg gtgcaccgca
    17401 aacaatttgc aatactgtcc cattgtccac ttctgtctca gtaatcgata aatggtcaga
    17461 gtcaggatgc gggacgcatg tttttacata cccgacaacg atcttcggtt catgatcagc
    17521 ttcaagctgt tcttcgaatc ctgcttcttt aatcaatcga ttcaatttcg ctaattcttc
    17581 atctgttaag cttacttggc cgttcccttc aattgttaga tgatcggaga tatggaaaaa
    17641 gttccaagca acaacttgac cttgttcatc tttgatccga gcaacattcc atttacgttc
    17701 gacagtgttt tctgttcctt tatcgtcggc tatgataacc atcaaagtgt ctccgacgtg
    17761 tgctttgtta taagcaaaaa tcatgttctt tcctccatta tcctttgctg agatttatct
    17821 taacaaaaaa ttgcattcac tgcatgagat ttttttcatg ctttatttcc gaagaagctt
    17881 cttctggaac accatttatt cgtaacaagg gactgtgaca agacttttgt cacagtccct
    17941 ttactgtttg attaaaaagg ttatacaagt tccacttgct taattactcg gctgttcttc
    18001 ttcgtcagaa acgatcaaga catcacaagg tgaatgacgt atgacgtagc tggctacact
    18061 tcctgtcata aagcgttcga ctgcatttag tccagactgc ccaaccatga ttagatcgat
    18121 tgcatatttt tttggcaatt tgactgccat ggattcacga acagagccgt atgcaataat
    18181 tccttctata tttgtgtaat caacagattt tccatattct ttacattctt cgatcatttg
    18241 cttggctgtt tcagtttgct gatcgactag attttgatca ataggagcat agcccataaa
    18301 attataaaat tgctgatcga ttacgtttgc tacatatact ttcccattat tacggcgagc
    18361 cacttctaac gcttttttga aagcagcaag tgcttgttca ctaccgtcaa tacctactaa
    18421 aatgttctta tattcttgat tcatcttgac ccctcctaac agatgtcagc cttttattac
    18481 actttctagg aacgattcga tttcctgttt tgttttacga tctttattca ctagacgacc
    18541 taattctttt ccgtcttgga tcacgacaaa acttgggata ccaaaaatgt tccattcagc
    18601 ggctacatct atgtacttgt cacggtctac ttcaataaat tgccaatcag aaaagtcatt
    18661 ttcgatttca ggcatttgcg gtttgataaa acggcagtct ccgcaccagc cggcagtaaa
    18721 gaaaaataca ctttttccag tttctacgta gcctgctaat tcttctaaac tatttgggat
    18781 aatcattctt tttcctctac tttctgttta tgtatttttc aattaaatta tacacctttc
    18841 tttcgaacta acaaacattg atcctctttt tataaaaaaa atctgacaaa aggttgcttt
    18901 tgccagattt tatagtttca ctatcgcgtt atttcccgta tacgatcgtg ttcactgttg
    18961 atttatctaa acctttcaat gtttgaatca acatttctcg tgcagcttca aaatcgcgaa
    19021 tactgaacat cgtttgatgc gtatggatat aacgtcccac tacgccaatc actgtacttg
    19081 ggattccttc attttgtgta tgagcagcac ctgcatctgt accgcctttt gaaacaaagt
    19141 attgataagg gatgttgttt gtttcagcga tatctagcaa gtactcacgc aaacgaggaa
    19201 gcatgatcaa acctggatct tggatacgca tcaatgtacc ttctcctaaa tgtccgaatg
    19261 tgccattttt cgtcactgtg tcatctgctg cagagcagtc tactgcaaag aacagatctg
    19321 gcttgaattt attgacagaa gctttagaac cacgcaagcc tacttcttct tggacattcg
    19381 cgcctgcaat caatgtatga cctaatgttt cattttgtaa cgcttctaaa gcttctaata
    19441 ccattgtaca gccatagcgg ttgtcccacg atttgctgat gatattcttc ccgttggctg
    19501 ttttgatcgt ttcagcgtaa ggaacgattg tgtctcctgg aagaacaccg taactcattg
    19561 cctcttctct tgattcaaac ccagcatcga acaaaatatc tgttacttct actgattttt
    19621 gtccgcttgt tcctcgtaat aaatgtgggg gaacggaaga agaaatacat ggataattct
    19681 taccagtaga ggttttaagt gtaaaacgtt gagcagaaac aacgtaaggg ttccatccgc
    19741 ctagaggtac gactttaaaa agcccgtttt cttggatttg tgtcagcatg aatccgactt
    19801 catccatatg tgctgcgacc attacacgag gtgcatccgc ttcttcatgg tggcgcagcc
    19861 caaaaatgcc gcccaaacca tctaactgta actcatctac cagcggttcc atatgacttt
    19921 ccatataggc gcgaacgtct tgttcaaaac cgcttgttcc ttgtaattct gttaactctt
    19981 tgattcgttg aaatgttttt tcttccatat gctattcgtc taaatttcag actaaactcc
    20041 tctcagactt atattgatct gcggataaaa tatgattttt tctgcagacc gatcgtattt
    20101 attatagctt attttttctg gtagcggtta tttatttcaa agaaaatatg agagtgtggt
    20161 aaaataaaca caaagagtag caagtgagaa gaaggaggta tatccacatg tatgaagaaa
    20221 gcgaattaag ctattttaaa ggcgggttag ccgttgggat cggtctagga ttattgagtg
    20281 gggtagcttc aacgatttgg tatcatcgca aaaaagtgtt atcagcagac caagtgcttg
    20341 aaaatatcaa aacatctttt ttaaaagaag gcgcaatcga aggtgcttgg atctcttttg
    20401 aaaaagaacc tattcggaaa ttcgccgttc ggtcgagtgc ttatcggggt gggctttccc
    20461 ggatagaaga tggcgaaact gtttattatg aatttttagc agatgctcat acaggaaccg
    20521 tattagacat ttcaagaaaa aagggcgcaa tagattaata cgtcaaaaaa atgaaataac
    20581 gaatacgcac ccactatcta aaagagaggt atcctatcct tcttttatag tgggtgattt
    20641 ttataaaaat agggctattt cctcttggaa tagctagtat ttgtagttat tatacggtat
    20701 tcttgaaata agattagttt tattatataa ggagagtgac aaatggaatc acgtgaaaaa
    20761 attgccgtgc tcattccttg ttataacgaa gaggcgacaa tttcaactgt tattgaagat
    20821 tttaaaaggg aattaccaga agcagatatt tatgtctatg ataataattc gaccgatcga
    20881 acatacgaat tggccgttca aggcggagca atcgtaaaga aagaaccacg tcaaggaaaa
    20941 gggaatgtaa tccgtcaaat gttttttgat attgatgccg attattattt gatggtagat
    21001 ggtgatgata cttatcctgc agaagctgca catggtttgc ttgagaaatt acgttctggc
    21061 gaagcagata tggtcattgg cgatcgtcta tcaaatggaa cctattttga tgaaaataag
    21121 cgtcctttcc atgattttgg gaataatctg gttaaaaata caattactta cttatataaa
    21181 acaaaaattc gcgatgtcat gaccggctat cgaggattca atcgaatttt tgtcaaaagc
    21241 ttccctatta tgagttctgg ttttcaaatc gaaacagaat tgacgattca tgctttagat
    21301 aaaaaattca agttcgttga gattccaatc gattatcgcg atcgtcctga aggtagcgaa
    21361 tcaaaattga atacattctc tgacggattc aaagtgatca tgatgatcat caaaatgtgc
    21421 aaagattata aacctttgct tttctttggg atctggacca tcttcttctt tttatttgga
    21481 ttggtcatgg ggattcctgt gattcgtgaa tatatgctga caagctttat tacacgcatc
    21541 ccttctgcga ttttaagtac tggattgatg actttagccc ttctttcatt agtaacaggg
    21601 ttgattttgg atacggtcgt cacaaatgcc aagaaagaat atgaattgaa tttataccat
    21661 gtctaccacg aatatcaaaa taaagaaatg aagtaggagg ccttttttat gcataagaaa
    21721 aaggagaatc tatttcctac tttttttgca actttatttg cgtcaggttt tgcttttttt
    21781 acttcttatg gtctaggaac tttgaatcca acagtaatca ttggtttagc catggttttg
    21841 ctacttgctt ttaagcaata tggaatagag ttgttttcaa taaaaaacaa agttgcagct
    21901 attgcccgat tgtttttttc tgcagctttt gctcttacac tttctattgg cagacagata
    21961 caatttcagt atgtctcagc aaactataca aagacaacga ttgctgatgg aagtattttt
    22021 tactttcttg tttatttctc catttttgtg tattcttttt tatttttaca atcgatttat
    22081 ttatcaatgc caaaactgga aacatttttt actgctcaaa acacacaggc tttctcttca
    22141 agaaaatatt ttttattctt tactgtcttt ttagttctgt gttggcttcc ttatctgttg
    22201 gcattgtatc ctggagtggt tttgcctgat tcgttaagtt cggtcgccca atctatgggt
    22261 gatgttccta taagcaatca tcatccagtc ttattcacct tactggtcaa gctatttgtt
    22321 catgatttac caactgatac gatcaatcac ggtgtatttt tattttcgat ttttcaaaca
    22381 ttgataacag cttcagcgat aagttattct ctttgctggc tgttaaaaag aaacatccat
    22441 ttttttccgg tactcattag tttatgctat tttgcatttg caccggtttt tccaatctac
    22501 gccttgaaca tgcaaaaaga tactttgttc tctatcgctt gctttttatt ttccttagcg
    22561 gtttttgact ttatttttca acgagaaaag ccaacgattc tcaatcagat ttacgtaatc
    22621 atccttgctt tactgaccac ctatctaaga aataatggga tttatgtagt aaccggcaca
    22681 ggtttgattt gcggcttgat tattttgaaa caaaaaaggt atcaagcatt ctttcaagtg
    22741 gtgctgggtt atacagtgat tgctggacta ctcatccacc cgttgatggc tcgttatgct
    22801 attcctacag aaactgctga acaattaggt gttcctttgc agcaaatttc tagaactatt
    22861 gttatggatg gtgacttgtc taagaaagat aaagcattca tgaatcagct actcccgata
    22921 aaagattatg aagcgtattc tcctagtctt gcagactcaa tcaagtggca taaaaatttt
    22981 aacaatgagt ttttgaatac acataaaaaa gaatttctat cactatgggc aagaaattta
    23041 ccaagtaata taaaaatcta tacagatgct tatattttag aaacgttcgg gttctgggta
    23101 cctggtacaa aaaatagtta cggcttttta gatactcgtg taaacacgaa taattatggt
    23161 atgaagcaag tagatttgat tgaacatctt actggattgt caggaatgaa aaaaatcatc
    23221 gatgctcgtg atttctttgg ttccggcaca ttactgtggt tagctatcgg cagtgcactt
    23281 ttagcaatct ttaagaaaaa atatcggtat ttactccttt ttcttcccgg tatgcttgtt
    23341 tttgctacta ttatgattgc tactcctgtg gcttttagtt tacggtatgt gtttgtttta
    23401 gcattaggtc tacctgttta tatcctctct ccttttttac tagataaaag agaaaaaatg
    23461 aaaacagata taggagatac tcatgaaact atttaaaaag atattttttg cttttgttct
    23521 cttgatcgct agctattgcg tactactgac aattactttt ttcattccgc agcactctat
    23581 tgaatcgaat gcagaaaaat ctctacagat ggttgaaaaa gaaggaatgt atccttctat
    23641 caatcaagga aatatgctag gcactcggtt agataatttt actgatcatt tgatgatacg
    23701 aaaaacaaaa gcagatcctg aattgaactc cttggagaac gcgatgtcta tggcggatta
    23761 tccccgttat tggcatggtt atcagctttt tttacgacct ttactgctag ggatgagttt
    23821 ggggagtatt cgaatgattt acgcagccat tctttttctg ctgattggat tgacgagcta
    23881 ctttttaacc aagtgtagcg acatctattt aacgacagcc ttgttgattt cgcttgctat
    23941 aggaaatgct gcaacctttt tcttcagtat gcaattttca aatatttgga ttttgacttt
    24001 attgtctgta ttactatttt taacaaaacc acaactctcc aacaccaacc aacaattatt
    24061 cttgtatttc tttgtcattg gttctttagc taactttttt gacttgttga caacaccggt
    24121 catctcttgg gggatacctg tgatcattat ttattatgta acaaataagt atttaatgga
    24181 taaacgcagt tcattgagca aacaagtagg cagttttgtt tttaccggta tcttttgggg
    24241 attaggctat ggtttgacat gggtggctaa atggatccta tcatcgatca tattgaacaa
    24301 aaacattgta aaagatgcaa tcaaccaaat cctctttcga acggaaggaa acgacaaata
    24361 cccgttgcat cgattagaga tgctgaaaag caatattaga ttgatgtatc caaaagtagc
    24421 aatattattg ctattgatta cttgtcttgt ttttctctat tttgcttatc gtaaacgaaa
    24481 tagctggcgt ccgttccaac ttctagtttt gtttgtttta gctgctgtaa cgccgtatat
    24541 ttggtacaat attttagcta atcactcaca gattcattat tggtttacgt atcgtacgca
    24601 aatcatcaca agttttgcta tacttagtgc tttcgccttt ttgatccctc ctgagaaatc
    24661 aaaagacgaa ctaaattact tttaagaata ccgatgtact aattcatttt taaacataaa
    24721 aactccagct gtcagagata gccggag
//
LOCUS       DACDAF010000035        24577 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.035, whole genome shotgun sequence.
ACCESSION   DACDAF010000035 DACDAF010000000
VERSION     DACDAF010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.035"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(152..550)
                     /locus_tag="IVZ69_001339"
     CDS             complement(152..550)
                     /locus_tag="IVZ69_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HAP8183430.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(547..1320)
                     /locus_tag="IVZ69_001340"
     CDS             complement(547..1320)
                     /locus_tag="IVZ69_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAP8183431.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(1317..2000)
                     /locus_tag="IVZ69_001341"
     CDS             complement(1317..2000)
                     /locus_tag="IVZ69_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HAP8183432.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(2167..3054)
                     /locus_tag="IVZ69_001342"
     CDS             complement(2167..3054)
                     /locus_tag="IVZ69_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8183433.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(3051..3920)
                     /locus_tag="IVZ69_001343"
     CDS             complement(3051..3920)
                     /locus_tag="IVZ69_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8183434.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(4057..5343)
                     /locus_tag="IVZ69_001344"
     CDS             complement(4057..5343)
                     /locus_tag="IVZ69_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP8183435.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            5616..6194
                     /locus_tag="IVZ69_001345"
     CDS             5616..6194
                     /locus_tag="IVZ69_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP8183436.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            6194..7123
                     /locus_tag="IVZ69_001346"
     CDS             6194..7123
                     /locus_tag="IVZ69_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8183437.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            7120..8856
                     /locus_tag="IVZ69_001347"
     CDS             7120..8856
                     /locus_tag="IVZ69_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP8183438.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(8919..9755)
                     /gene="pheA"
                     /locus_tag="IVZ69_001348"
     CDS             complement(8919..9755)
                     /gene="pheA"
                     /locus_tag="IVZ69_001348"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HAP8183439.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(9752..10261)
                     /locus_tag="IVZ69_001349"
     CDS             complement(9752..10261)
                     /locus_tag="IVZ69_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HAP8183440.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(10254..11549)
                     /gene="aroA"
                     /locus_tag="IVZ69_001350"
     CDS             complement(10254..11549)
                     /gene="aroA"
                     /locus_tag="IVZ69_001350"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HAP8183441.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(11562..12653)
                     /locus_tag="IVZ69_001351"
     CDS             complement(11562..12653)
                     /locus_tag="IVZ69_001351"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HAP8183442.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(12670..13836)
                     /gene="aroC"
                     /locus_tag="IVZ69_001352"
     CDS             complement(12670..13836)
                     /gene="aroC"
                     /locus_tag="IVZ69_001352"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HAP8183443.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(13838..14902)
                     /gene="aroB"
                     /locus_tag="IVZ69_001353"
     CDS             complement(13838..14902)
                     /gene="aroB"
                     /locus_tag="IVZ69_001353"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HAP8183444.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(14935..15957)
                     /gene="aroF"
                     /locus_tag="IVZ69_001354"
     CDS             complement(14935..15957)
                     /gene="aroF"
                     /locus_tag="IVZ69_001354"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HAP8183445.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(16616..17590)
                     /locus_tag="IVZ69_001355"
     CDS             complement(16616..17590)
                     /locus_tag="IVZ69_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HAP8183446.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(17571..19454)
                     /locus_tag="IVZ69_001356"
     CDS             complement(17571..19454)
                     /locus_tag="IVZ69_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HAP8183447.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(19472..21697)
                     /locus_tag="IVZ69_001357"
     CDS             complement(19472..21697)
                     /locus_tag="IVZ69_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP8183448.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            21812..22846
                     /locus_tag="IVZ69_001358"
     CDS             21812..22846
                     /locus_tag="IVZ69_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8183449.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(22913..23926)
                     /locus_tag="IVZ69_001359"
     CDS             complement(22913..23926)
                     /locus_tag="IVZ69_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP8183450.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(24004..24192)
                     /locus_tag="IVZ69_001360"
     CDS             complement(24004..24192)
                     /locus_tag="IVZ69_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HAP8183451.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         7063 a         5341 c         4397 g         7776 t
ORIGIN      
        1 gcatattttg aaaagaaagt ctgatgctta gagtagaatt tcataaaaat ttactatttc
       61 ataagtattc acgagaaaaa tacaaacaaa aaagcggaaa taacgctcat ccgccttctt
      121 gtttgtgttt atttcctctt caaacgcttg tctatgattc agacttttct ctatcgttat
      181 tttcatctaa aagttcttgc attccgataa tttctcgata ttgatgaatc ttagtgatac
      241 caatgacttt gtctacatca atactaaaac aaataccatt acctggaata tcgatgttga
      301 tgccttgacc aatcgcatcc attactttat tcgtcaaact atcgggtact aatgtcaaca
      361 caatatcttt ttctggcgaa atgtccaaac ctaaaaattt ccctgaatca tgtacaccag
      421 aacctcttcc atgtaagatc gttccgcctg ctgcacctgc ttcttttgaa aagtcgataa
      481 catcttcgcc cattcctccg tcaacgatcg tcacaatcat gtgaagattc aatgctacaa
      541 gatctttcat ttgctttccc ccaatttttg caatctttct ttttcgattc tgtctttttc
      601 atcttttcgt ttataaatat atcctagtac taaagtggat aatattggtg tcaatgcaat
      661 cattgcaacc acaccaaacc cgtcaatgat cggatctctt ccttcaattt gtgcagcgat
      721 tgccacgctc attgataaaa taaatgtcga acacatcggg cccgttgcta ctccaccgtt
      781 atcaaaagcc attgctaaaa agatcttgtc cacttttcgt cctaaaataa atgctagccc
      841 gtatcctggg atcaagaaat aataaagaga gaatccgacg agcaaacgcc acatagacaa
      901 tcctactgct gcgccgatcc caattgaaat taccatcagc atgattttcg atcggattct
      961 cccctcgctc aattcttcaa cctgtttgat cattacatga atcgccggct cagcaaaccc
     1021 tactaagaac cccattaaaa agccaagggg aaccagtata taattgtaag gcaatcccgc
     1081 aatagcactg cctaaatgct gtcctaccgg tacataagcc atattgactc cgtgcaggaa
     1141 aaggatcaac ccaatagtcg ttatcaagaa acctttcata atgtcaaaga aacgcttttt
     1201 gcgcatacga aaactaatga tattcattaa aacaaatagg attacgatag gtgccactgc
     1261 caaaatgact tccatggtaa cgatttcgat tccatctatc acttgctgcc agaaactcat
     1321 tggaagatca cccccaaaat catcacggca agaatcggcc ctaacgaagc aataccgacc
     1381 attccaaaac tgtcattttc atttttcttt tgtttgatca tactagtcat ccctccggca
     1441 agggccaaga taaatggaac agttactgga ccagtagtca ctccccccga atcaaaagca
     1501 atcggcataa attcggaact ggtgaaaaat gaggcgatca aaacgcctat gtagcctata
     1561 gccatcaatt gataatagga tagcttgaat acgacccgaa gcagcgcaaa ggctagaaat
     1621 actccagtgc cgacgctgac gatcccaatc agcaacactc tgccaatctc tccgtcagat
     1681 atatcatata cttgttgtcc caaaacttgc acggaaggtt cagcaatcgt gatcacgatc
     1741 ccgatagcaa atcccaaact gaccaaaacg gtcaaacttt tctttttgat catatatttc
     1801 cctactagat ctccgacttc catcatagaa taatctgctc caaacaaaaa gagcgtcatt
     1861 ccgatcatca tgattgccgc accaaccaga aatgaagcga ggtcttctcc ttctaacggt
     1921 gcaaaaacaa acgttaaaat gacaatcagg acagtcatcg gcaatatagc agcaatcact
     1981 tctttaaaat tttttagcat gtatcctcct cctttactct ttaagtttac cttaaaatga
     2041 aagagttttc gagcacaaac ttaaaacgtt atcatttaat ttttctcaac ataaaataac
     2101 acacgtccca aaagtatctt tttacttgga aaaatgactt tgaaggaacg cgcttattgt
     2161 gtttttttat tttacagagc cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa
     2221 tacgatggca gttggtaaag tagcgatgac taatccagcc atgatcattc catagtctgg
     2281 tgtataggaa gcacccatag cagataaaac aagcggaacc gtccgtttat caggagattg
     2341 caaagctact aagggccata aataattgtt ccagctactc atgaatgtga tgattgcagc
     2401 cgcggcatag gtatttttag ccgtcggcat atacactcta aaaaaaatac ttagttcttt
     2461 tagaccgtct aatcgagcgg cttctactag atcttttgga aaagatttaa cattttgtcg
     2521 aaagaagaag atcaaaaaag cagtgctaac agatggcagg atgacaacca agaaactgtt
     2581 gattcccaaa accgttccgt tcaattgtga aaacattcga tataaaggga tcatcaatgc
     2641 cgcaaaagga accatcatcg atagcagtag aatattgaaa attaggtctt ttcgtttact
     2701 ttgataaatc tcaaatccat atcctgccat tgacgaaatc agcaatgcaa acacagtggt
     2761 caccaaagcg atcatcgctg aattccaaag ggaacgagta aaattcagct cattggaaaa
     2821 caaattttga aaattgatga tcaagttact gccaatcttt atttttcccg atgtgatatc
     2881 cacgggtgta ttcgtcattc ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga
     2941 taggatgctt aatgctgtat actttaatac tgacccaatt gtcgaacgaa gttctaatgc
     3001 ttgttttttg acgttggggc gttcgattgt ttctttttct accatatttt tcatcgactt
     3061 tctcctccta ctttcgtttg gattatcgac aatatcacaa taaaggaaac aataacaaag
     3121 gaaactgctg ccgcatatcc aaaattaggc gtgaatttat aactcaaatt atagatgtat
     3181 tgagataggg tggtcgttgc atttgctggt cccccgccag taatattttg tacttcatca
     3241 aaaagctgca atgtcccgat cgtcgaagta atggaagtaa acaaaatgat tggttttaaa
     3301 tttgggatcg tcactttgat aaactgctgc catttagaag caccgtcaat agatgctgct
     3361 tcataaatct ccgaatcaat attttgcatg cctgaaagga aaaaaatcat attgtatcca
     3421 gtccaacgcc aagtgatcga aagaatgatc agaactctcg cccaaattgg atgagtcaac
     3481 cagccaatcg gtgtgtcaat cataccaatg cccaacaaca agttgtttac aaggccagat
     3541 tgagaaaata gacttttcat gatcagagaa taactgacca tcgaagtgat acatggaaga
     3601 aagatagcgg ttcgaaacaa ccctttatat ttcaactttt tatcatttaa aaggttggaa
     3661 ataaaaagtg ctagaaacaa catgatcggt acttgtacaa gtaaatacag gaatgtatta
     3721 aaaaaagctt ttttaaaagt tgcatctgtc aacatccgct gataattacc taacccgtta
     3781 aatgtcatat tgacaggggg accactttga aaagacgtga tcaaagccaa aaccatcgga
     3841 ataaaaacca tgattgatat caaaatgact ggcaagatta aaaaagcatg cccgtttttg
     3901 aataaatctt tctgcttcat tcttttccct ccaattctat cattgattat ctacatgaaa
     3961 agacaagaaa gacaatatct gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg
     4021 atgaaaaagc gaagaaattc acttttttac caccgatcaa ttagccaatt gtgcttctac
     4081 ttgtttttgt gtatctgcta gtaccttgtc tgtctcttct ccattgatga ttcgatgaag
     4141 agcttcagct acgactgctt caattgcata ggtctcatgt ccgtaattca cttctggtat
     4201 ttcagatgtc catgttgaaa aatcgtcaaa gatcttttga ccactgtaaa attcagaagc
     4261 ttcttgataa gcttcttgtt cattcgcgct aagcatcgta gatactagtc cgatttcttt
     4321 cgcaagagtg cccatcagtt cttcattcga agcaaacgtt gcttctagga aatctttcgc
     4381 tgaatcttct ccagctactc ctttgatcac ataccagcca gcgccgccaa ggttagaagc
     4441 ttgcgctttt tgcagatttt ctggaagtgc aggtattggt gcaatcttcc attttccaga
     4501 ttggttttct gctccttgga tcgttgaaga ataccaagcg ccagttgggc tagaagctac
     4561 tgctcctgat tgtatcgcag ttactccagc attccagtca gaggtttgtt cgactagatc
     4621 ttctttcaaa agagtggcaa acaattcaag accatacttt aaagatgcat tgtcttggat
     4681 cgtgactgtc tccccatctt cagatgtata ccattctcct gcctgttgca taatcatcct
     4741 tactcgacca aggtcagaag gattgacttc agcgattttc tttcccgtct tttctttgac
     4801 atctcgcgct acttgaatat actcgtccca cttcagattc tccatatcct cttctgtata
     4861 acctgcttct gccatcagat ccgtacgata gaagtttgct gttacgcccg aatcgaaagg
     4921 aacaccgtat attttatctc ctactttgtt taccgcaaat ttatacggtg caaaatgatc
     4981 ttcctttaca atagcagaca aattagcgaa tgcatctgga taagaagtca aatagccttg
     5041 tatcctataa tcttcaatca agacgatatt gggcaatcct tctgtattcc cgctcgctaa
     5101 agcggtgttc agtttctgaa cgatatcatc ctgagacatc gtaacaactt ctatctctgt
     5161 ttcttcgttc tcataaactt tttttgcttc attcactgct ttgatattga atgtctcatc
     5221 ccacgcccag acagtgactt tttcttcttt gtctgctgta ctactagcac ttccgcatcc
     5281 tgttaagaaa cctgatgctg ccgctaaaca aacgactcca gcaattaact ttctgatgtt
     5341 catttttatc cgctcctttt ccatccatta gttgtttacg tttgctacat tcatcatacc
     5401 aaaatttgaa aacggtttct ttattattca gatacttcaa aaatttctcc taaaataata
     5461 aaaaaataca aatcaactat gacaaaagga ataatcttag catctagacc aaagatcgaa
     5521 atggtgaggt ttctttaaaa taaaaatatc cttgcatttt ctcctagaaa taagtatttt
     5581 taaattacaa gactattctt aaggcgggta aaaaaatgcc aatacgcgta attcttatcg
     5641 atgatgaaca gacgatttta gatggaatga aacagttgat caattggtct gagcacgggt
     5701 ttcaattaat agggactttt tccagtccgc tgaaagcgct tgatttttct ttggtacatg
     5761 caatcgatat cgtggtcaca gatgtaatga tgcctgaatt aaatggaatc gaattatcgc
     5821 ggctattaaa acagcaacaa cctgaaacac agatccttat cctctctagc tatgatgaat
     5881 ttgatatggt taaagattct tttaaagaag gcgtcgctga ttatctttta aagcctcgat
     5941 tgagtcctga tttttttcta aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc
     6001 ccaacaaaag cccaatcacc aatcgttatg agcagatctg cgagaatctt tcacagcaga
     6061 ttgctggaca aactcgtcca ttgcttgacc ctcttctttt tgaacacacc ttgtttttct
     6121 gttatatacc gaaaaacggc cattcagttc aaaacaaggc tctaaacaaa aacagtcgat
     6181 cacccattca ttgatggata gcgacgattc gtttactatt tatcctgttt ctaccttttc
     6241 ggaagaatcc ggctatgtaa tcaatactga ttccaaagat acacttagga agtttgttca
     6301 aaagtttcgt caagaagttt ttccaggtga tttttttgtt gtttctgatt cttttgcaat
     6361 ccaagatatc aatgaaatat tccaagagat cagaaattgc accaaaggac aacgtttcta
     6421 tcataaggga aagaaccttg cttatcagca tgaacttctt ccgttattaa ccaaccacga
     6481 gcagcaagca agtagttatt taacaaaaat cgttcataaa gactacgctt tagctgtcaa
     6541 agaacttgag aatttcttca cgacgatatt ggaacagcct attgatccag cttatttgaa
     6601 acatgaggca atcaatcgtt tctatgcatt actcaacgct ttggctgacg agcatgttgg
     6661 gaatgaagaa ctttctttgc tcaagatcgc ccttccttct ttattagccg atgctgagta
     6721 tttcgaagat ttttctattc ttgtcaaaga aacacttgag aaactcaccc acttttctgc
     6781 aaatgcaaaa aaagacaatt tcgatatctt gactttgatc tacgagttcg tccaggaaaa
     6841 ttatgagaaa gaaatcaatt tacaactttt atccgaaaaa tatcattttt catatagcta
     6901 tctctcagcc atctttactg aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt
     6961 ccgtatcagt aaagccaagc tctttttgac ggaaacacgg cttactttga cggaaatctg
     7021 tgagaaagtc ggctataccg aactgggtta tttctccaga gtttttaaag aagagacagg
     7081 aatgacacct tctcaatacc gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag
     7141 catgaactct ttgccaaact tctgttcatt ttgttcatcg gtctttttct gcaagccatc
     7201 gtcatttctt tgtttattta tcatcgatca agggatgcct atatccagct gttcaatcaa
     7261 tcgaatgatg tggtactaaa aaagattcaa tctgaatttg aaagtttgaa tgatacaatc
     7321 gagaatacat tagccgcttt tgattctaat ccagctgtca aaagctattt ttccaatgat
     7381 ccagcccaac atatggaaca gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct
     7441 ctttcaaaaa tccatccaat gatcgattac gatgtattga tctttggaga aaatggaaga
     7501 acttttgtcg gaaacgacat gctcactgcc gtatctgccg attctttttt tcaatctgcg
     7561 attgctcaga gagtgaatga acgtgctgct gatacacaaa tgctttttgc acaccacgga
     7621 ttgactcttc gcgataagaa agcacccagc gtcttctttg tcaaaaaact gaaaaataca
     7681 ttgaatcacg tttacggata tgctgtttta tcgatctcat ccaagcaact agcgaatctt
     7741 tttcaatctg tagtaaatcc tgagatatcg aagatctcct tcatgaacga agaacagacg
     7801 atcatcgcat caaatgaaga aaatacaatt gggagccgat caatgatttt caaaaaacta
     7861 acagtaggtg aaacaacgat ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc
     7921 caggattgta cattactcag tcaagtcgat cttcattctt tatctaacca aatgggcgtg
     7981 atttttccga ttattttgta taatatcgtg acacttgctt ttgctggctc attggtattt
     8041 atgtatttgg atcgacacac aaaatcgatc taccgcttga ttgattcgct aaaacggcta
     8101 gaggaagatg gcttaaaagc tactgttcct gtacaaggaa gccatgaagt ccaattgcta
     8161 gggaatacga tcaatcaatt gctaagtaat gctcagcatc attatgaaca gacgatccaa
     8221 gacgaaaaga agaaacgttc gcttgaaatc caaactatgc aagcacagat acagccccat
     8281 tttatttata atacgctgac tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa
     8341 gcagttcaag gaatcgacag tttcattact ttactaagaa gtacgattgg gaaaaaagaa
     8401 gaagtgattc cagtcaagga agaaatcaaa agcgtacaaa gttacatcga tcttttgagt
     8461 atgcgatatg gcgaaagaat ctcggctaaa ataatgattc ctgatgaact gcagtcatta
     8521 tctatgccga atatgatcct tcaaccaatt atcgaaaacg cctatcttca tgcttttcac
     8581 aataaaacgc aaggattcat cacggtgtac ggcaaaacaa aaaatcagct tcttttattc
     8641 gaagtgattg ataacggcga tggcttcgat actgaaaata ccaaacaaaa aaatgatcat
     8701 ttttcaggaa tcggcatcag ccatgtagat gagcggatac gcctaatgta tggcgatgca
     8761 tatggcttaa cgatccaatc agtgattggg acaggaacga ctgtaacgat ttgtctaccg
     8821 cttcttccta aaaatcaatc agaatatcaa aaataaagaa tagccaagcg ctgatttttt
     8881 tattttaagt taaataaatc aatcagtatt cttgactttc atctacgcgt ctcttctact
     8941 gtcagcactg gataacagcc caatatttga ctttctcctc cgagcatctt gatttcttgg
     9001 agcgcattct ctactaatgt cattggacgg tccaacaaca aatcgatcac gaaaaaatat
     9061 tctcccaagc tagttttcaa tggtcgggat tcaatcttac ttaagttgat ttcccgccag
     9121 ccaaaagctg ccagcatttt atgaagcatc cctggccgat tagcaggtag tgtcaagatg
     9181 acactcattt ttactggagc tgactgctgg ctggtcatct ttcggtcacc gacgatccaa
     9241 aaacgtgtct ggttcaactc attatcttgg atattctcag ctaagatctc caatccaaca
     9301 tgctgtgctg tttctaatga agcaatcgct gctgcgtctt ctttcggatg ttctgctaca
     9361 tacattgctg cagcagttgt tgattctgtt gctactaaag gaacattagg ataatgcgtt
     9421 tctaaaaact gttgtgattg tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt
     9481 gttgctggat tgcctaaaag ctgctgcttg ataggaagaa cgatttcact tttaacttcg
     9541 acttctggat gtttggaaag aagatcgatt gtgtgatgaa cagctccttc caatgaattc
     9601 tctacaggaa cgacagccag atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg
     9661 atggaagcat acgcagtcaa ttgttctgta ggaaatagct gacaagccgc ctgataagtg
     9721 aatgaacttt ctggccctag atagctgacg ttcatatgct tttgatcctt tctataatgg
     9781 tatcgatgat cttttctggt gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt
     9841 cataccaaga aagtcgttgt gccaataatg cttttatttc ttctcttgtt tttccaagag
     9901 ctaaaggtcg aatagacgtt tcatcttgtt ggatacgatc aactagacag tccgcttctg
     9961 cctctaagta aagaacaatc ggctgtgttt ttaaaaaacg ccgattttct gcactttgga
    10021 caatccctcc accagtcgcg ataattttgt cttcatttga cagctttctt aaaatatctg
    10081 actccacttt tcgaaagctt ttttcaccgt aatagtgaaa atattcggca atcgacaatt
    10141 ggatatgttc ctcaatcttt gtatctaaat ctacatactc tttttgtaaa cattgagcta
    10201 accctttacc gattgttgtt tttccagcgc ccatgaaacc aatcagcaaa atgctagcca
    10261 tgagcttctc ctcctgacac aagttctgct aaatcgtcaa aaaatgccgg ataagagatt
    10321 gaaacagctt cagctccttc tagttcgcaa ggtccatcag ctatcaaagc agctacttgc
    10381 agcatcatac cgattcgatg atcgcctctg ctggacactt ttgcgccatg cagaggtgtc
    10441 ggcccatgga tgatcagacc gtctgctgtc gcttttatct ttgctcccat tttctgtaat
    10501 tcttctgcca ccgcatcaat tctgttggtt tcttttactt ttaattcttc tgcgtctttg
    10561 atgatcgtga ttccttctgc ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc
    10621 agacgcggaa tgatttctcc accaatcgtt gctttcttca aatgactcgt cttgacactt
    10681 aaatcagccg attggttctg ttcattgtga ttcgtctggg taatcgctgc gcccatctcc
    10741 tccaacacat ctaagatacc agttcttgtt ggattgaccc cgacattttt taacaacagt
    10801 tggctttccg gaacaagaag tcctgctgct agaaagaaag cagctgatga aatatcacct
    10861 ggaacagtta tctgttgacc agttaatttt tgcggtccgg tcactatgat cgttttatct
    10921 tccactgtga tccttccgcc aaattgacga atcatttctt ccgtatggtt acgggaacgt
    10981 tctttttcaa cgattacgga tgtgccttct gcttgtaatg ccgcaaacag caaagcagat
    11041 ttgacttgcg cactggctac aggcatattg tatcggatag gtgataaaga gcgggttcct
    11101 gtcacagtga ttggtagata ctggtcattt tcttctcctt gcaagtcagc gcccatctcg
    11161 cgtaaaggtt ccatcactcg ccccattgga cgtttagaca acgaagcatc cccgaacaga
    11221 gtagtcgtaa aaggctgtcc agccaaaata cccatcaata aacgtatggt cgtaccggag
    11281 tttcccatgt caattgattc ggttggttgg acaaatgagt ggctaccgcg accatgaatc
    11341 ttgatcacct cttcctcttc ttcgatctcg acacctaatt gttggaaggc atgtaaagta
    11401 ctcagacaat cttctgcgcg caaaaaattt tgtatagtcg tcgttccttc agcaattgct
    11461 ccaaacatga tgctgcgatg ggaaattgat ttatctgctg gtatcctaac agtccctctt
    11521 aatccatgta tttgttgtaa taattgcatt tatccagcct cctatttgat ccagcaatga
    11581 taactggtat tagacataat gattcttttt gcttgtaaca aatcctgttg gtttttaaaa
    11641 ctgatttgca gtattcctaa aatatcttcc ctggtctctt ggatcttcaa attaatcaaa
    11701 gaaactcccg cttttccgat cagtccagtt acttctgcaa taacgccagg ttcatctggc
    11761 acatcgataa ataaatcaaa aaaggcagga atcgcgcctt gcttatggac aggcaactgg
    11821 tctcgacttt cttttgcccg attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg
    11881 atccattctg ctatttgtgt catttcttgt tgccaatctg ccaatcgttc caataatatc
    11941 tgcttattgc tcaacaaaat atctgtccac atgacaggat ctgaggaagc gatcctagtg
    12001 atatctcgaa agcctcctgc tgccagttgt ttggctcgcg gatactcttg attgaattgt
    12061 tctgcctgat tgactaagcc agctgccaga atatgtggaa aatgacttag cattcctgtt
    12121 atacggtcat gttctcttgc tgtaagagtt acatattttg ctttggttcc gcaaaatagt
    12181 tcttgcagtt tttcaacatc ttttttcgtc ttttccaaag gtgtaaagat gtaataggca
    12241 ttttcaaata gtttagcatc tgctgcctgt atacctgatt tatgagaacc agccattgga
    12301 tgtccaccga caaaccgaag atttttctgc tcagcggatg tcacgacttg ctgcttcgta
    12361 ctgctgacat ccgtaatgat gacgtgatca gacaagttga ttctttcaag gacatcaaga
    12421 taagctaagg ttgtacggac gggaacggct aataagataa cgtctgcttg ttctgcacct
    12481 gtttcaaaat cacttgcaac gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt
    12541 tttgactgac tatcccaacc aactactatc agttctggat tggtctgacg aatacaaagt
    12601 gccatagaag caccaatcag tccaagcccc acgataaaaa catgttgtgc catcttattt
    12661 gccccctttt tagtaatgtt tcaagtagtc acggtactcc ttcactgcag ctttcaactc
    12721 aacaagcgaa tcacttggga attttgacaa tagctctgtc gctaccacag tggctacaac
    12781 attttccgca acgacgctag ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc
    12841 tttgtaaggt tcttttgtat cgatatcaac actttgaagt ggcttgtaca atgtaggaat
    12901 gggtttcatg accccgcgaa tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc
    12961 gcctagatta ttggtacgtc ggaaatagcc tctttcttct tcccatagga tctcatccat
    13021 cacttctgag cctggtaatg aaccagaagt gaatccgacc ccaaattcta cgcctttaaa
    13081 ggcattgata ctaaccacag cttgtgcgat tttggcatct agcttcgtgt cccattgtac
    13141 gtagcttcct aatccagctg gaacgcctcc aacgagcact tctacaattc ctccgatcgt
    13201 atctccattt ttctttgtct gatcgatcaa atcttttatt ctttgctcaa ctgctggatc
    13261 aacaactcgt acttctgacg cttcagaaat ttctttgatt tcttgaatcg agatatttcc
    13321 aggtatttct gcttggattc caccaagaca aatcacgtgt cctgctacga tgatgtcaag
    13381 ttcttccaga attttcttgg caattgcgcc gattgctaca cgcatggtcg tctctcttgc
    13441 agaggaccgt tcaagcacat tccgaagatc tcgatgatgg tatttcatac cgcctaccaa
    13501 atccgcgtgt cctggacgcg gacgtgcaac tcgccgcagt gattggtctt tttcaggcac
    13561 ttctgctaca gacatgacag ttgtccaatt tttccaatct ttattttcta ccactaaagt
    13621 gacaggtgaa ccaattgttt tgccgtgacg gatgccagac gtgatccgaa cacgatcttt
    13681 ttcgatcttc atccttcctc ctctgccgta accagcttgt ctgcgagcga gttcgtgatt
    13741 gatttcttct tctgacagag gtaatcctgc tggtagtcct tcaataatgg ctgttaattc
    13801 tggtccatgg gattctcccg cagtcatata acgcatctta cagtcctcct aagtaatctt
    13861 tgaatgtctc tgtgggaaca ggaacgattt ttgcttgccc aatcttttct agcaagatga
    13921 tattcaattg gcttcctctt gctttcttat catgggttat cgcgtggaat aattcatctg
    13981 gatgacttag atcgtacgta atcggcagat ggaatttttg aagtatcctt tctaaagcag
    14041 ctgtcgatcc agttggagac aagccgattt tttctgcatg agaagtgatg gctaccattc
    14101 caatagctac tccttctcca tgactgacta ccccatatcc tgctgtattt tcaattgcat
    14161 ggccaattgt atgaccaaaa tttaaaataa gtcgatttcc ttggtcaaag acatcttctt
    14221 ccactacttt tcgtttgatt tccaacgtag cagtaatgat tggaacagca tgttccagaa
    14281 gatctttttc gtctttcagc tcgttcagct gtttccaaag cgttgcatct gctatagctg
    14341 ctgatttgat gatttcagcg attccttctc gtaaacgacg taccggcaaa gtttttagaa
    14401 cctcaggatc aatcaataca ccagctggct ggctaaatgt tccgacaagg tttttcgctt
    14461 tgtttgtatt gactgctgtc ttcccgccaa tactagaatc tacttgtgca agtagcgtag
    14521 tcggaatttg aacgaaatgg atcccacgca tgaacgtcga ggccacgaat gctgctagat
    14581 cacccaccat tcctccacca agtgcaagta tcccatcgct gcgggtaaaa tcattatctg
    14641 ctaaaaaatc gtataactca gctgcttgtt ctaaagattt actggtctca cccgccggta
    14701 cgattgaaag gactggttca aaattagctt gtctcaattg gaacatgatt ttttctgcat
    14761 atagtggagc aacgtttgta tcagtgatca cagctacttt ttgaggtctc caaatcgttt
    14821 gaagccatga tccagcctgt tctagtgcgc ctttttcaat atgaatatcg tatttttggt
    14881 tatcaacatg tacagtaagc attcgtttca cttctttctt ttaaaaagct ggaattaatc
    14941 gagtgtctga atcttttcca ttgcttcttt catgatcgca acttctttca tcatgcgtga
    15001 gtaagtcttt tcattcaacg attggggacc gtctgaccaa gcatttgcag gatcaggatg
    15061 gatctctacg atcatgccat ctgctccgct tgccacaccc gcacgagcca ttggtggtac
    15121 aagttcccaa attcctgtac catgacttgg atcaacaatc acagggaaat gagttaattt
    15181 tttcatcaat gggacagcac ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg
    15241 aatcccacgt tcgataaaaa tgacaggaga tttgtcttcg actgcaatgt attctgcagc
    15301 attaagccat tcattgatcg taccggaaat tccacgtttc aatccaacag gtttacctgt
    15361 tttaccgaca gcagatagca gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat
    15421 atcgctgtac tcagccacca tatcgatatg cccttcatcc atcacttcag taatcacttt
    15481 cattccaaat tcatcagccg cttgacggat gtatttcaat ccttcttctt ctaaaccttg
    15541 gaaagcatat ggagaagtac gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc
    15601 ggctttggcc attcgcgcac attctctgat ttggtctaat ccttcgatag aacaaggacc
    15661 agccatcgtc acgaaactgc cgtcaccaat ttttactccg tctacatcca cgactgtatt
    15721 gccaggatgg aattctcgag aagtcaattt gtatgtgttt aaaatacgca cagcattttc
    15781 tactccttca tagcgtgtaa atgctccttc ttgtaaactt cgcgtatcac cttttagtcc
    15841 aatcactact cgttctgttc cttgatcgat tgagactttg aatccttctt tttcgatatg
    15901 atcgacgact ttttttattt gttcttccgt tgcttctttt ttcataatta ctatcattgt
    15961 ttttcccgct ttcttttgtt tacttatcta tcttggctga ttttctctac tttttcaagg
    16021 tggttttaca ttaattccta ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc
    16081 tttcctactt atgacccaga taatcaacaa aaaaagatgt ccctgtagga aattgcctct
    16141 acagtgaaca tcttcaacga gccttaaaaa gcgctgcaaa aatataaaat agccactata
    16201 gatgaatttc tctacgtggc tgtaagtcgt gtttaaaaat ctttagccat catagataca
    16261 aacctggttt gtttgtaccc acgaagtcat gaatacaaac ctatctaaaa tagctaaagt
    16321 aatacgtatt cagttttgta agttttctag atttcataaa aaatcgctcc aaactgatgt
    16381 aagaattgta cctagtatag acataaaaaa atcgactgtc aatcattttt atgaaacttt
    16441 ttttaatttt ctgatagtta actttgtttt tcagaaaaat aacaattggt tttattgaag
    16501 aaaatagtca tgaacaaaag tatctgagaa cttttttact ctcttgttca tgacatatag
    16561 aataaagcag ctttgtcttg taaactccgt ttttcaaata ataatctaaa gattgctact
    16621 gaataataaa gccgatttca tggtcctctt cgctgctgat tcggtaaggt gactcaacat
    16681 ccgctcccca gctattgata cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg
    16741 ttcgtctttc tggcggtagt tcttctatat gtgttgcctg ttccagttct tctgctttga
    16801 atggtaaagc ggaaaaagca aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt
    16861 cttgatcttt atccgtatta tccaacgttt gatttcttgt tagttctacc catttcgttt
    16921 ccatatgcat gccgcattct tggggaacaa ggtatgggga aacggggagt cctgccactt
    16981 tataaatacc ttcgacacca ccagccatcc gatccggata tgtttcccct gataggcctt
    17041 catactcaaa aaattttgct ttcgttggca taatgaacct taaacccaat gcgggtaatt
    17101 ccggtaatcc tttttgtcca taataatgca tattgacaag cattttaccc tctccagcga
    17161 tttggtagga aattgtcact tgggtttttg gtactgtgtt gatttccagt gtaaaaatga
    17221 tttcaaccgt ttcagcgtat tcattacttg aatattgatt atttactgga gcaatcggca
    17281 aatcgatctt tttattgtcc accagtactt ctatttcttt gacttttgga tacaatccgg
    17341 ctcctaacca cataccggat ttaaatccaa atccgctacc tctgtcatta tcggtcgttg
    17401 ctcgccaaaa aactggaagt gtttcccggt atagccattc ttttccgttt ttattgagcg
    17461 attccagtcc gcctcttgta taagaaaaaa tataatgcgt attccccgat ttgacaccta
    17521 atgtacagtc gccgaagacg attgcaactt tttccgtatc catatgactt ttatttactg
    17581 tatttttcat aataatatct tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa
    17641 acgatcccat tccctgagaa ttcatagtca cttggtttat cgtcaaagtc accgccatag
    17701 cgcatcactt ctctgcctgt gattggatca gtcacttgga tcgcctgatc tttaaaatcc
    17761 catatatagc ctccttggta catttcataa cgatcaagca acgtcatgta agaatccatt
    17821 ccacctaacg aattccccat gtcatgcata tattcacata agatgaacgg tttttccgct
    17881 ttattttcaa ggtagtcaat gatctcttct ggtggcgcat acatgcagct ttttacatct
    17941 gaaatcgaat cttcgaatgc tggatttgga aaattccctt cataatggac aagtcgatcg
    18001 gggtctactt ttttgaagta atcgttcatt tgtcgaatgt tttcttccgc ataagattca
    18061 tttccaagag accaaaaaag aatacttgga tggtttttta atgtttcgaa attcgttttt
    18121 gctcgatcaa gaacagccgc ctgccactga ggtactgcac ctggtacgtt gtaagaaggc
    18181 tcaaatgcgc ccattttttg ccatgagcca tgggattcga ggttcgtttc cgccatcaca
    18241 tggattcctg cttggtcgca taaataatac caagtgatct ggttggggta atgagatgtc
    18301 cgtacgccgt tgatctttgc attttttatg atagccaaat ctttttccat atcttctata
    18361 gtgatggcgc gtcctttttt cggatgccac tcatgtcgat ttaccccgtt gataatcatc
    18421 cgttttccat tgaagtagat gattttatct ttgatttcga ttttacgaaa accgaaggaa
    18481 tagtcaatat actccgttac tcttttttct tcgtctatcg tctccaattc aagcttatat
    18541 aaattgggct gaaaatgccc ccacagtgcc acattttcaa atccatcgat gcgaatcgtc
    18601 atttgctctt ttaacggata ttgctgttga tagatttcct tcccatcagg atctagtatc
    18661 gctacattca gctgactgtt tttggctact tgctcaaaag acaaatctac ttcaagtttg
    18721 ccattttgac atttgtcatc taagcgaggt ttgatccaaa gatcttctaa atggttttgt
    18781 cctcgagcaa ctaagaagac atctctgaag atcccaaaaa atcggaaaaa gtcctgatct
    18841 tccaagaatg cagctgtact tcttttgtaa acctccacag ctagaatatt ttcttcttcc
    18901 aaataaggtg ttaaatcaaa ttcagacgga gtgaacgaat cttcggcata cccgataaaa
    18961 tgaccattca accaaataaa cattgcttgt tctacaccag caaaatgaat cgagatttgt
    19021 tttcccttta gaccttcttc taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct
    19081 ttagcagctg aaaagatccc ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg
    19141 cgaaatacat gtccctccca cggatacatc gtattgatgt aatggatctt gtcataattt
    19201 gctaattcaa tatgactagg aacagtgatt tcatcaaaag aacaggcatc aaaatctttt
    19261 ttataaaatg tttttggtcg taccgaagga tttggcgaat aacaaaaacg ccatgatcca
    19321 tttaaagact gtttaaggga ggatgtggtt tctacttctt cccttgttgc ataacaaaca
    19381 tgatcgctat gtgcatttga ttggttcact ctaaaaactt gtggatcatc taaccatttt
    19441 atatttgctt tcatactttt ttccttctct ctcataactt tttgaaatga agcagttctg
    19501 tttggaaatc accttgaaaa tcggggaagt aaagtccaac tgtcatcaat tcggcccccg
    19561 aaaatatccg cttcgaggtc tgttcctgat aaagtgcctc atcatctaac cccatcagat
    19621 atacttcatg gaacgctggt tgagctgaag ctagtatcct ccctaaaaac acaatagctt
    19681 catcttgttt aggagacaca aacatccatg cggcaatatt ttcttcaaaa ggactcgcca
    19741 aacgataata atggccatac tggatcaccg gacgaatcgt ttgataggat ataatttggt
    19801 cttttacttg ctttttttct tcaggagaca gctttgtcaa atccagttca taaccaaaaa
    19861 cagcgctcat agctgtttct cctcttgttt tcaacgaagt agatctgtcg gtctgatgat
    19921 ttggtacagc tgatacatga gctgtgatgg acgaaatcgg ataagcaagg cttgttccat
    19981 attggatttt catacgctcc actgcatccg tgttatcact tgtccatgac tgcggcatat
    20041 aataaataaa cccggcatca aaccgtccac ctccaccaga acagccttcc cataagattt
    20101 ccggataatc agttgtcaaa tgttcaagta gttcataaag cccgagcata taacgatgcg
    20161 ctacttctcc ttgtctctgt gggtcaaggg taatcgaata gacatctgaa agcgaacggt
    20221 tcatatccca tttgatgtag tcaagaggaa tcgtatctaa aatctttctc atttgtttct
    20281 caatcgtctg ccgaacatct aaccttgtaa aatccagtac atgttgtgat ctggaagcag
    20341 aaggcattct acctggctcc tgcataagaa aatcaggatg tgttcgatac agttcagaat
    20401 caaccgagat catttcaggt tcaaaccata aaccaaattt caatcctttg ctatgagcat
    20461 aatctgctat ttcacgtaat ccatttgtca acttgccttc atactcgaac cagtctccta
    20521 atgaagaatt gtccgcatct ctttttccaa accagccatc atctaatacg aacatttcga
    20581 tgcctagctc ctttgcttca tcaatgatcg ccttgatttt ttcactattg aagtcaaagt
    20641 aagtggcttc ccagttattg accagaatcg gccgttcagc aaattgatga cgacctcttg
    20701 cgattctttc acgtagcaac tcatggtgga tctgactcat tttgttcaat ccctgacttg
    20761 agtaagaaag gatcatttca ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa
    20821 aacgatggct gttgatccca ccgacgactc tcaattgatt gatctgatct ttttcaagtt
    20881 cgaaagaatg gttgccggaa taaacaaatt gaagtccgat cgcttctcca gtattttctg
    20941 tcgtatgatg atgaactaaa gcaataaagt tattcatatg gtgactgctc gttcctcgac
    21001 ggctttcaaa tacttttgtt ccagataaaa cagattgccg tgaaatctgt ctttcattga
    21061 catgtgctcc tggcaaagca atgacttcat caaatcgcct agtatgggca aagtctagct
    21121 ggaaactagc cgctttttct agtttgattg tttctccggt ttcatttctt atctttacag
    21181 atcgtgtgat cactgctcta tcagtaaata tggtatagaa caaatcgaaa taaatcgctg
    21241 tttctctatc cttaagtgaa atcaccaacg tttgtgcctc tgacttgtcc atcacataag
    21301 tttgaggcaa gccttcgatc tctggcttcc catctgtaat ataatggctg tcatatctca
    21361 gatccagtaa gtctgatcca ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca
    21421 tgctgccatg agaagagtat tcttgcggta gtgtatcttt cgacagagac cggtcaggat
    21481 ttaagggaac atttcctgaa aatccacgat ctcttcgggg ataattttta ttgtctttgt
    21541 actgcttgac tggtttgcca aaataaatat gcgccaatac attgctttct tctatcttta
    21601 tcagataaga aagaaatgta tttcgtaaat ggaagactcg gctcttttca tcaaataaga
    21661 tgaaattttt atctgttttt ctatgcgtaa tatccatcat ttcactccca acaaaacgga
    21721 aaccgtttac ttttttttat aattcctgta tactgtttac taaacaattt tgtcaataaa
    21781 aattttttat ttttttgagg agtgtgtaaa aatggttgga attagagatg tcgcacgaaa
    21841 ggcaaatgtc tctcctgcta cagtttcccg tgtgttgaat aacgatcaga cgatccatgt
    21901 ggctcagact actcggcaac ggatagtaga ggcagctgct gcgttggatt atgacatcag
    21961 tactcgtaaa tatatcaaaa agagaatgcc ttcgattggt gtgatctcta cgatcggcaa
    22021 agcgagcgaa gaacaggata tctattacaa acatttgcga gtagggatgg aagaagaagc
    22081 tcgacgtctg catttaggga tgaatcgaat ctataatcta tctgataatc ctaaacaatg
    22141 ggaagatcta gatcagttag gtgcggtgat cgttgttggg actgttacga aagaatcgat
    22201 taccgccttg ttaaaacaaa acatgcaaat agtcgtcgtg gataaccctg acatccagca
    22261 agaggtcgat atggtgtatg cagatcttga acggatgact aaaaccgtac tggaattgtt
    22321 cttagaaaat ggtcataaaa gaatagccta tatcggggga tataaagtcg atatggatga
    22381 attcggtggg aagcagattt ctataaatga aaagaggatg cgtgcctatc agcattttat
    22441 gatcgatcat cacttagaaa aatatatgtc ttatcatcta ggtggctgga cagaaaaaca
    22501 aggtgaggta cttgcgacta atctattaga aaatgaatcc cctcttccta ctgccattct
    22561 tgtcgggagc gatccaatgg caattggtgt ctatcgggca ttgaaacaaa aaaatatcca
    22621 aattggagaa gagattgttg tagcaagctt tgataatatc gagacaatcg caaacctctc
    22681 ccctggcttg accagtgttc aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat
    22741 ggcattggag cgaattgacg gtatacggga cgaaccaatc attttgactt atcctgcacg
    22801 attgattgtt agggaaagtt ttatcccaag aacaaaaagg tattgaaaga gaggttgtga
    22861 aaagccgctt cgtttcttca tactcaaaac gaaacggctt tttcacaacc tcttacttat
    22921 acttattcac aaaatccaat gtctgctggt aacaattttg cgattctttt agcgtgtaat
    22981 caaattggta ttcatgggta atctcttttt ttgtatctgt ataaaacaag gattgcacgg
    23041 gtacctttaa ttctgtcaac cgattttcta atgcttgacc ttgctcctgg aatgagtatg
    23101 catttccgtc agttatatac gttggcggaa attccttaga aacatggtca gccacactag
    23161 cttctttcaa ttgctcactc gttttccaat cttttgttcc aatcaacgac cacgcaacgg
    23221 ttttgacgaa aaacttcata aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat
    23281 caacaggtcc gcaataagaa atggttcctt tcagactatc ttttggaagt agctgtttga
    23341 ttttcatttg tttagcatac gcatcattcg tttgtatagc tgcatattgc aatgcgattt
    23401 gtgaacctgc actatctcca ccaaaaaata attgttccat gtctagcaat ttgtcgtctt
    23461 tttcttcagc taataaatct ttgatcagtt cattcacttg aagaacttga ttagggtatt
    23521 ctgaatcagg cgctaattca taattcatcg caaccactgc gatgttggcg tctgaaacta
    23581 attttgtcgc aaattctttg acacccgatt tatctccgcc gacgaatcct ccaccatgta
    23641 cccaaaatag aacaggaaca ggccccttgc tgttttttgg atagtagatg tcataagtat
    23701 tctctttata cttggactca tacgtcaaat ctgttttttt cgccacgttt ttttctgctt
    23761 gatcgaacgt ttttttatca gtgatttgaa cagtatttga aaacatatgg ttgatcaaga
    23821 atgctccagg tctgggggaa agctggaagg caagaaagat tgcaaacgcg atcccaagaa
    23881 tgattccgaa gaaccatccg ataaatttaa gaattttctt tttcataagg ctccctcagt
    23941 agttagtatt aagcattctg attataccat agtgttattt cctatcaagc tctcctagat
    24001 gatttaatga ttttccccaa acttcttctg caatgctttt gacaaaagaa attttttcca
    24061 ttgttcttca aacaaaacat tttcttcttc tgttgaagca aatccacatt gaggacttaa
    24121 gcacaaacga tccaaaggca gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg
    24181 gtgctcttcc atttcgccat ttttcgttac agtcaaaatc taagacaact aatttatctt
    24241 cagagacttt ctctaaaaga acaaaactcc cagcacgttc actatcgtat tctaaataat
    24301 aggcacggac attttcttga gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg
    24361 ccgccaaaat cgaataataa tttccgcgtc aaacatgtat atttagtgtt gaatcatttg
    24421 agaatatgaa aataaaaatc tttttgatca atcagttaat caaattgaaa taacgaaaaa
    24481 tctgagacag aatgacgttc attctgaccc agatttgatt ttgcacaact caacagtcct
    24541 tattggcaaa tcgccaaaat aatgtagact aactaaa
//
LOCUS       DACDAF010000036        24370 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.036, whole genome shotgun sequence.
ACCESSION   DACDAF010000036 DACDAF010000000
VERSION     DACDAF010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.036"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..833)
                     /locus_tag="IVZ69_001361"
     CDS             complement(<1..833)
                     /locus_tag="IVZ69_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP8183452.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     Y"
     gene            complement(1057..2997)
                     /gene="thrS"
                     /locus_tag="IVZ69_001362"
     CDS             complement(1057..2997)
                     /gene="thrS"
                     /locus_tag="IVZ69_001362"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HAP8183453.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(3334..3513)
                     /locus_tag="IVZ69_001363"
     CDS             complement(3334..3513)
                     /locus_tag="IVZ69_001363"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HAP8183454.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(3560..5383)
                     /gene="cadA"
                     /locus_tag="IVZ69_001364"
     CDS             complement(3560..5383)
                     /gene="cadA"
                     /locus_tag="IVZ69_001364"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP8183455.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5661..7940
                     /locus_tag="IVZ69_001365"
     CDS             5661..7940
                     /locus_tag="IVZ69_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HAP8183456.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(8033..8680)
                     /locus_tag="IVZ69_001366"
     CDS             complement(8033..8680)
                     /locus_tag="IVZ69_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183457.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(8859..9578)
                     /locus_tag="IVZ69_001367"
     CDS             complement(8859..9578)
                     /locus_tag="IVZ69_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP8183458.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(9709..10860)
                     /locus_tag="IVZ69_001368"
     CDS             complement(9709..10860)
                     /locus_tag="IVZ69_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HAP8183459.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(11077..11817)
                     /locus_tag="IVZ69_001369"
     CDS             complement(11077..11817)
                     /locus_tag="IVZ69_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP8183460.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(11821..12144)
                     /gene="rsfS"
                     /locus_tag="IVZ69_001370"
     CDS             complement(11821..12144)
                     /gene="rsfS"
                     /locus_tag="IVZ69_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HAP8183461.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(12201..12794)
                     /locus_tag="IVZ69_001371"
     CDS             complement(12201..12794)
                     /locus_tag="IVZ69_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP8183462.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(12778..13425)
                     /locus_tag="IVZ69_001372"
     CDS             complement(12778..13425)
                     /locus_tag="IVZ69_001372"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HAP8183463.1"
                     /translation="MNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHLV
                     MAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIELA
                     RGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPGY
                     TTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(13438..13749)
                     /gene="yhbY"
                     /locus_tag="IVZ69_001373"
     CDS             complement(13438..13749)
                     /gene="yhbY"
                     /locus_tag="IVZ69_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HAP8183464.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(13765..14874)
                     /gene="yqeH"
                     /locus_tag="IVZ69_001374"
     CDS             complement(13765..14874)
                     /gene="yqeH"
                     /locus_tag="IVZ69_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HAP8183465.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(14871..15398)
                     /locus_tag="IVZ69_001375"
     CDS             complement(14871..15398)
                     /locus_tag="IVZ69_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HAP8183466.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(15578..16363)
                     /locus_tag="IVZ69_001376"
     CDS             complement(15578..16363)
                     /locus_tag="IVZ69_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HAP8183467.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(16356..17225)
                     /locus_tag="IVZ69_001377"
     CDS             complement(16356..17225)
                     /locus_tag="IVZ69_001377"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HAP8183468.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(17226..18605)
                     /locus_tag="IVZ69_001378"
     CDS             complement(17226..18605)
                     /locus_tag="IVZ69_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HAP8183469.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(18613..19032)
                     /gene="fabZ"
                     /locus_tag="IVZ69_001379"
     CDS             complement(18613..19032)
                     /gene="fabZ"
                     /locus_tag="IVZ69_001379"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP8183470.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(19057..19533)
                     /gene="accB"
                     /locus_tag="IVZ69_001380"
     CDS             complement(19057..19533)
                     /gene="accB"
                     /locus_tag="IVZ69_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HAP8183471.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVISEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(19536..20771)
                     /gene="fabF"
                     /locus_tag="IVZ69_001381"
     CDS             complement(19536..20771)
                     /gene="fabF"
                     /locus_tag="IVZ69_001381"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HAP8183472.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGTKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(20790..21527)
                     /gene="fabG"
                     /locus_tag="IVZ69_001382"
     CDS             complement(20790..21527)
                     /gene="fabG"
                     /locus_tag="IVZ69_001382"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HAP8183473.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(21539..22456)
                     /gene="fabD"
                     /locus_tag="IVZ69_001383"
     CDS             complement(21539..22456)
                     /gene="fabD"
                     /locus_tag="IVZ69_001383"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HAP8183474.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEATPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(22563..22787)
                     /locus_tag="IVZ69_001384"
     CDS             complement(22563..22787)
                     /locus_tag="IVZ69_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HAP8183475.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(22840..23802)
                     /locus_tag="IVZ69_001385"
     CDS             complement(22840..23802)
                     /locus_tag="IVZ69_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HAP8183476.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(23812..24252)
                     /locus_tag="IVZ69_001386"
     CDS             complement(23812..24252)
                     /locus_tag="IVZ69_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP8183477.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
BASE COUNT         6663 a         5427 c         4244 g         8036 t
ORIGIN      
        1 aaatattctt ggattgcttc tcgtgttttt ttcacttttt cgctaagctt ttcgttttta
       61 gccatataga aataaaaaat gatatcgatc gtagcaaatt gggccaaaag tgaattagtt
      121 gccgcacttc gattcgtgat ttcttttggt ctagatgttt gtacgagtac atcggctatc
      181 ttgctaagcg ggttatttcc aaattgcgtc aacgcaatga tttcgatatt catgcttttc
      241 gccagctcgg ctaatgcgac tacatctgca cttctacctg agtttgaaac aagccaaagc
      301 actttctttt tctcattgct gacaagttgc gggagcaaga cgtggatatc tttttcaaaa
      361 atgattggct taccgacacg agaccatttt tgcagaatat cttctactac taaagaagag
      421 gcgccaaccc catataaaaa aacagtctct gccgattcca aacactctac gactttttgg
      481 atcgtttctt cttctagaat atctactgtt tcttttatcg ctacttgtgc attgttacca
      541 agtttgtttt tgatagagta aaaggactca tttgcttcta tatcactaaa accttcatcg
      601 attccagtct gtagttctgt tgaaatcgtg attttgaagt ccgtcagact ttgaaaaccg
      661 atttttttgg aaaaacgtac aactgtcggc gcactcaacc cggaagcttc tgctaattca
      721 ttagctgtca ttgtagggac cttctcaata ttaccgataa tgtagttggc caactttttt
      781 tctgctgaag aataatcttc catcatactt tcaatacgac taattacgct cataagttcc
      841 tccacccttt taatgatagt ctatgtaagt ataccatatc agacccttat tcacggtcgt
      901 atactggata aaaaacaaaa aaacaatccg cccaacagaa tatcttatcc catcaatccc
      961 acagattcta ttgagcatct gtgtctttga ggaatacctg ttatctattg ttcggattgc
     1021 tttctatcta ctactttttt acaggaaatt tacctattag ttttctctgc tgtaattttt
     1081 gacttctgct tccatagcat caataaagat attcaaatct tctacagctg tttctttact
     1141 tccataacga cgtacgttca ctgttgcatc ttccaattcc ttgtctccaa caactaattg
     1201 gtaagggatc ttttgtgttt gagaggcacg tatcttatag cccatttttt cattacgatc
     1261 atcaacttct acacgcaacc ccttcatttg caaacgttct ttgatttcat aagcataatc
     1321 gccatgtgca tcaacagaaa cagggatgat tgttgcttgt ataggtgcca accatgttgg
     1381 aaaagcgcct ttgtatactt ctgttaaata agcgacaaaa cgttccattg tagaaacaat
     1441 tccgcggtgg ataactactg gacgatgcgt attttccccg tcttctccaa catatgtcaa
     1501 atcaaagcgc tctggcaata agaagtctaa ttgtatagtt gataatgttt cttctgtacc
     1561 aagagctgtt ttgacttgaa catctagttt tggtccgtaa aaggctgcct cgccttctgc
     1621 ttcaaagtaa tctagttcta attcatccat agcggctttc agcattgctt gggctttttc
     1681 ccacattgcg tcatcatcaa aatatttatc tgtattgttt ggatcgcgat agctcaagcg
     1741 gaaacgataa tctgtaatat tgaagtcagc atatactgcc accatcaatt caagcgtacg
     1801 tttaaattca tctttgattt gatcaggacg aacaaatgta tgaccatcat tcaacgtcat
     1861 ttctcgtaca cgttgtaaac ctgacaaagc acctgatttt tcatagcgat gcatcattcc
     1921 taattcagcg atacgaattg gtaattcacg ataagaatgg atcgtgtttt tgtagaccat
     1981 catgtgatga gggcagttca ttgggcgaag aacaagcatt tcgccatctc ccatatccat
     2041 tggcgggaac atgtcttctt gataatgatc ccagtgtcca gatgttttgt acaactcaac
     2101 atctcccatt attggtgtat atacatgttg gtaacctaga ctaacttctt tgtctacgat
     2161 ataacgttcg atcgtgcgtc ggattgttgc cccttttgga agccagaatg gcaaaccaga
     2221 acctacttct ggggaaacca tgaacaagtc aagttctttt cctagtttac gatggtctct
     2281 ttcttttgct tcttcacgga gacggatata ttctttcaaa gctttcttgt caaaaaaggc
     2341 tgtcccgtat acacgttgca tcatttgatt gtttgagttt ccacgccaat aagcacctgc
     2401 cactgataat aatttaaata cttgtatacg gccagtggat ggaacatgtg gtccacgaca
     2461 caaatcgatg aattcgcctt gttgataagc agtaatcact tcttcttctg gcaattcact
     2521 aatcagttct actttgtacg gatcacttgc aaaaatttct aatgcttcct gttttgaaag
     2581 aacacggcgt tcgatcggca gattttcttt gacgattttc atcatttctg cttcgattgc
     2641 cggcaaatct tctgcagtta cttggttttg tccattatct gtatcgtagt aaaaccctga
     2701 atcgatagct ggtccaacgc caaagtggat atttggatag aggcgacgca tggcttgggc
     2761 catcaaatga gctgctgaat gacggactaa gccaagtgca tcttcatggt ctggtgtgat
     2821 gatctcaata cttgcatctt cctcgattgg acgagtcaaa tcaacgagtt ttccgttcac
     2881 tttaccagct aaagcttttt ttgctaagct ttttgaaatg ctttcagcaa ttgccaatgt
     2941 tgttgttcca gactcaaatt ctttgactgc accatctgga aaagtaattt ttatcataat
     3001 agtttcctcc ttgaaatgtt ttgattgatc agatcatcaa gctgaaaaac aaaaaaatcc
     3061 tagcatctct tgaaaagaga tactaggacg aaaagttcgt ggttccacct aatgttcaaa
     3121 cgcaaatgcg ttcctcaagc gttgtaacgg tccgaccgcc cttgcttcaa caagggtttc
     3181 gaaagtggtc atcctttggt tttctcctgg aaaagtttca gcctagcttt tcctctctta
     3241 tcgaagactc tcaaattcag ttggctttct catcaatcaa ttatgtgttt atttaaccac
     3301 taataaatag aaaaatcaag tgggaaacta aacttatttt ttccattccc catttacacc
     3361 gtatgttcct tttttcatct cattgatgat gacatggatg tgttcttttg gtgcctgcgt
     3421 gtttttatga acagcttccg tgatatcttt catcatattt tctaattgtt ccggactgcg
     3481 accttctact aattcgacat gtacgaatgg cataatgctc tctcctcttt ctgatcgttc
     3541 ttttttcaac tcgattctat catactatgt ttgtcttggg tactgaatca ggaaaaatgg
     3601 ctggatcttt ttttgctctc aaggcactca aaatagagac cgtatccacg acttcttgca
     3661 aaacagctcc gaataatgcg gggattagtc ccgtacttgc aattaacatc aaaaaaatac
     3721 aaataaagat gccaatcagt acagactgtt tcgctattct catcgtatct cttgaaatca
     3781 ctactgcttt tgctacacgc aagagatcat ctttcaagat gaccgcatct gcactttcac
     3841 tagcagctgt agaaccatga gcccccattg caataccgat atctgcagca gcaagtgctg
     3901 gtgcgtcatt cacgccgtct cctaccatcg caacaggtct ttgatcttta gggatacttt
     3961 ctaaaatggt cagtttatct tgaggcaagc tacgggcatg tacagaatct aattggactt
     4021 tttctgcaat cgtttgagca atggcagatc catccccggt gatcatcatc aaatttttca
     4081 catcaagttt tcttagctcc ttgattgtct ttgctgcttc tgggcgaatc tgatccgaaa
     4141 ataggatcgt tcctgcaaaa gatcgatcaa ttgttacata gattgctgta ttggacgttt
     4201 ctatttcttc agctgaaaca aaagaggcac gtccaatctt tacttcatga ttattgacta
     4261 ctgcttggat tccttgaccg gtcacttctt tcagttgact aacaggatac agttggctgt
     4321 ttttcacgtt gttcactaac gaacgagcta agatatggct agattcctgt tctgcactag
     4381 ctgcatacag aagtagctct tcttttttta ttccattgac tggctgaatc gcctctactt
     4441 ccaatatccc tttggtaagc gttcctgttt tatcaaaagc aatcgttttt gtacgtgcga
     4501 gcttttcaat cgttgttcca gtttttacaa cgatcccgtt tttacttgaa cggctcattc
     4561 ctgcaactaa agcaatgggc gcagctagaa tcagtggaca aggtgatgcc actaccagta
     4621 cctcagcaaa tcgtaaaggg tcttttgaga accaccaaga aataccaccg atcaaataag
     4681 caatcaacgt gaaagggact gcataacgat cagctaaacg gacaaatcgg gcaggctttt
     4741 cttttgattc ttcgactagt ttaataatca tttgatactg gctgtctgcg gcacgttttt
     4801 cagcgatcat ttggatcgat ccgtctccat ttaaagaccc tgacataatc tgatctccag
     4861 gtttcttggt ttccgggcgg gactcacctg tcaaagaaga ttcatcgacc gaagattctc
     4921 ctttggtcac tcgaccatct gcgggtacaa gttcgccagg cttgactagt aactggtcat
     4981 caatatttat ttcatcgatt actatatcct gcaattttcc ttctttgaat cgatgggcaa
     5041 ttcttggggt gttatctaac aaagactgca gttctttacc cgctcgttta ttcgcgtaat
     5101 cctctagact atctccgccc gtaagcatga tcaatatcat caaactagcc cagtattctt
     5161 tgacggctaa tgttgcaagg attgcggtaa tcgctaatac atctacgcca tatcttcctg
     5221 aacgtaacgt cttgatcatt tccaaaaaca tcaagaaggc gagaatccct ccagtaaatg
     5281 cgacaatcgc aaatgcaagg gccggctggt gaaaaacaaa ttcacttaat aaagctatcc
     5341 caccaataag caaagtaagt aaaaattttt tgaaatgtgt cattgttttt tctcctcttt
     5401 tatgtgactt agagaggtta gtaataaatt tccagctgcc tctttcatct taagcatagt
     5461 ccttgactag cactttttaa aacaataggc cttaattgaa aacaactatc actatcagcg
     5521 tttccaaaat tcatcagttc tacaaacaaa aatattcagc aaggattact ttttcgattc
     5581 atcagttaaa aagtaccttt tttcgaaaaa ctatgctata cttttaattc gttatttacg
     5641 gcggaaggag caaacatgcg atgaatgaga aacaactaga acaaacgcac gtggatgaaa
     5701 cgatcgaact aatccagatc gaacaaaata tgctggatac aaaacaacaa gaattgactc
     5761 aggaaatgaa tcattcgaca aaagacacag ctaatcacaa gattcgagct ggttccaatg
     5821 aagcttttta tgaatctgct gttgaatatc gccaacatga gcaggaattg cttttgaaat
     5881 accatactct tgaagcacag caaaaacgcc tgcaaacgtt gtctgtcatg aaagatagtc
     5941 cttattttgc ccgtatcgac tttaaagaag accgtgaaac agaaacatta tatctaggta
     6001 tcgcttcttt aagagatctg gcagaagaaa caatcgttat tgactggcgc gcaccaattg
     6061 ccaatcttta ttatgaaggt gagattggtc ccgcatttta tgaaactgaa acagatagaa
     6121 tagatgtcga tctgcagttg aaacgacaat ttaaaatcca agaaggacgt attttatcta
     6181 tggtagatac gtcggaagta atcaatgatg actttttgct agagatattg gatgaatcat
     6241 caagcaacca tatgaaaaac atcgtctcta cgatacaaaa agcacaaaat gcaatcattc
     6301 gggacacaac aagtaaagta atgctgattg aaggaatcgc cggaagtgga aagacatccg
     6361 ctttgcttca acgtattgct tttctgttgt atcataatcg caagtggctc gaggctgaaa
     6421 acgttcttct attttcaccc aaccatttgt tttctgatta catctcgact gtattgcctt
     6481 cattaggtga aagcggcgtg cctacacaga cattcaaaaa ttatttggtg cagctgctgc
     6541 cagagttttc tttactagat gaacagcaac aagaaagtgg ttttttgcta ggggaaaaag
     6601 atccgataca agtgatgaaa agcggattga ccttagtcga tcagattgat cgctatatcc
     6661 aaggcatcac aaactacggt cccttgttcc gtgatatgaa aataaatggc cgtacgatcc
     6721 tatcaaagga atcgattcgc caatggtata aagaaacaaa tgaacaatta cctttacatc
     6781 atagactttc tctattacaa acgaagctcc tgaaaaaatt aggcggtctg caaaaagacg
     6841 aaacacgtca gcaatgggtc aaagatctgg cggaagaaca gctccaagaa ctatacgcaa
     6901 cagatccaaa tcttgaatat acagaacaaa aggagcgttc attacgtaaa aaactggcca
     6961 accaaatcgt acgtaaaaga ttccgtcgaa tccatcgagg gatcatgaat tatcaatttg
     7021 tcaatataac gaaacaatat ctccactttc tacaaactgt gccactttct cttctaacac
     7081 gacataaaat cagcgagacc aggtggcagg aacatttgac aactgttcgt acacacttgc
     7141 gtcaaagaga attgcgtcaa gaggatgctg tactattctt tttactgatg cgccgaacat
     7201 atccagtgac ggttacacac aaagctcgct atatctttat tgatgaaatg caggatttcg
     7261 caccatcaca agtggcattg ctgcaagcct tgttcccaaa agcaaatttg actttctgtg
     7321 gagatctaaa tcaaaatgtc tttggaaatg aaacgatcgt tggatcattg gaagaccttt
     7381 tcgtggaccg tgaagtcact cgtttccaat taacgacaag ctatcgctcc acaaaagaaa
     7441 tcactgattt tgctaatcat tttattgtga aagaacatca agtagaaaca acagcaagaa
     7501 aaggagacct tcctttgctc atccaaggaa caacagatga tatcaaattg aattggttag
     7561 cagataccat tcgaacgact cagggaaaag cccggtattg gcgtacagca atcatagcta
     7621 aaacacaaga agaatgcgaa gctctttatg ctcaactgcc agacgagttg aaacaacaag
     7681 tccagctgat tttaaatgag agtgacttta tgaagcgttc cattatttta cttccagcct
     7741 ttttagcaaa aggtctggag tttgaccgag ttttcttgtg ggatgtagat gcagaacatt
     7801 tttcttctca gcaagacaaa ttgatccttt acaccatgtg tacacgtgcg atgcatgaat
     7861 tgaccctttt tacctccaat aatgaaagtc ctttgttaaa caatatggat atttcatctt
     7921 atgagaaaaa agtactgtaa gtaaaaagac aactgctatc attaatgtta gcagttgtct
     7981 ttttatttac aataataatt gcagaaaaag taattcaatc atttaaggtc atttattcta
     8041 tatataaatc caaatctgtt tcaggatatt ttaatttgac aagcgaaata atcattttca
     8101 gttcttccat gttttctgga tattctgggt caaatacctt gctatgacgg ccaatcccgc
     8161 cattgtcgat caatcggtaa attcgattcc attcaatgaa ttggtcaatt gattggaaat
     8221 tgctgattgg atagccgcca caatccaaaa tctctgatac acgaaatgct aggtatgcac
     8281 tatcgatcac tttatttttt ttcgtgtcta tcttctcatt tctttcgata agaatttttt
     8341 caggacgatg tttcaagctc cactctaata gtagaaagaa agcctccatc cgatactctt
     8401 cttcaaataa ccgaaaggct gaatcagaac gacgaaaaag cagcggaatc agataatttt
     8461 gtctataaat cagcattggt gcgcggtcca ccatacactc taaataacgg ttcagatacc
     8521 ctgtaccgac atagtttcct aatcgatagc cttcaacgcc gaatcttgcg tatttttgcg
     8581 ctaattttga acaatcagtt acgttcacag ctaactcttc tactttgcgg taaccgctta
     8641 agatacgttc aaaaggttct aaagtgattt ttgcttccat attcttcccc gtccatcttc
     8701 cacatacttc atatcatttc acatgatact tatgctctca tcataccaca ggttgaatta
     8761 gaaaagaaaa taaatcacac aaaaaagcaa gacaatctgt tagtgagatt gtcttgcttt
     8821 tcgaaaaaga ctgaatactt ttcgttaaaa ctggttgctt agtcttctaa tgccacatta
     8881 tggaacacat gctgtacatc ttctagatct tccagtgcat caatcatttt ttcaaatgtt
     8941 tcttgatctt ctggagatag tgttacctcg ttttgaggga tcatttggat ctcagcgatt
     9001 gaaaaatcag tgattccttt ttcttttaat gcttcttgta tactatggaa atccgctact
     9061 tcaccgtaaa cgatgatttg tccttcttct tccattacat cgcgaacatc gatgtctttt
     9121 tccattaggt attcaaggat ctcgtcagcg tcttctcctg caaaagcaaa gattgctgta
     9181 ttgtcaaaca tgtaagaaac cgctccggaa acacccatgt tcccgccatt tttcccaaat
     9241 gctgcccgta cgtctgctgc tgttcgattc acattgttcg tcaatgtatc aacaatcacc
     9301 attgagccgc ttggtccaaa tccttcatag cgcaattcag agtatgtttc atctcctgca
     9361 ccttttgctt tttcgattgc tcggtcaata atatgttttg gtacattata agttttagcg
     9421 cgatcaatga cgaaacgtag tttttggttt gcatgcggat caggatcacc tgattttgct
     9481 gccgcgtaga tttcaatccc aaattttgca taaatccggc tattattagc atctttagca
     9541 gttttctttg ctacgatatt tgcccattta cgtcccatat tttcacttcg ctttctgatt
     9601 tgatagtttc ataacgcaaa aacgtcctgt tccattatac ttgtgaatca cgattctgtg
     9661 aagctttttt tctttcttcc ttcattcttc tcatttttag tcaattatct atactcggat
     9721 tgggatttgc ccgaaattct gttccggaat attgcctccc aattgataga tttgatcact
     9781 tctaactaac agttccgctt cttgtgcctc tttttttccg attcgggaat aaatagaaat
     9841 ctcttttttt tcttttaaga atcttcttcc agcatcggta aatccaagta gtcgaagata
     9901 atttttattt tgttggacag gaatctcttg ctttttgata ttcagcaaga cataacaaga
     9961 taatcgttgg atccgtgtcc atgtatatct ttttgttttt acctttgaca caaaatcctc
    10021 aaaactatca gcagttgcag ctgctgtttt catgcgcgat tctattcctt cggtcatctg
    10081 atagatatct gtcagttcca gcaaagtaga agataacaac cgataacgca aatacggcca
    10141 ataagattcc caagtctgca gcgaacaagt tgaaagatct tcttctgtct gaggcggcac
    10201 aagtccagct attctttttc cttcttctaa cgcatggcga atggctgttg cactggctat
    10261 cctctgatct gtgatgattt tttcatgata gcctgcactt ttacgtcgga tcggatgtaa
    10321 ttccataggg tggacatact tggcattttc ctttgcataa cttaatccca agatatgatt
    10381 tggcgaagaa aaatcaagcg taatatcggg atacagactg cgaaaaacct cagtcatttt
    10441 ttgcggataa ctatacgttt gatcagacag ttcttgaaat gcctcttcta tcctatcttg
    10501 attctcttgg acaaagcgtc cgaaactgct gtaatcaaac gaagtctctt cttctgttcc
    10561 aaaacacaaa ctgtcacagt ccagtgtttg caagattttt actgcacctt tagcaaaata
    10621 gtcagctgac tgaaccgccc attcgacggg aagctccact actaaatcca caccattttg
    10681 taaagcttca ttcgcgcgat gccatttatc gatgatagcc ggttcgcctc tttgcaaaaa
    10741 attcccgctc attacagcaa tgacgacctc tgctcctgtt atttttcgtg ccatttccac
    10801 atgatagcga tgtccattgt gaaaaggatt gtactctacg ataatcccgc agcttttcat
    10861 gcgcatcctc cttcatagtt atcgataaaa aagaaataga gacaagtaaa aaaaggcaaa
    10921 aatcggaaaa aatacccgaa ctatataaac tattctcgca aacacaatac ttctgcgacg
    10981 aaaagctgca ctgcaagagc aatgcctata tcgttcggat atataattta tgttgaagat
    11041 ttattctttt cttgttaact cgagcaggca aaaccgctag tctttgtatg ctacaaagaa
    11101 ccagcgcttt gatttctctg atgctgcttc gtctgtaaaa tcagaaaatg cttcgacttt
    11161 cgaaaagccg ctgttttcca gcattcttaa ataactttcc aatggatagg tacgctcttg
    11221 atgtagttca tcttcacgaa taaatcgacc agacccttct tgttcttcaa cgaaaaaggt
    11281 aagaaaatgt tcgatgctgt gtttctcgct tcctggataa ctatcccaca aaaaagcaaa
    11341 attatcccct tgataatgat agctatattc tggaaaaacc tcatctactt gataggtgga
    11401 gtgtacgtca aataaaaatc ggccattttc ttctaacgct tgatagactt catcaaacac
    11461 ttgctgtacc tcttgtctat ttttcatata gcacagcgaa tcagaaaaac aggtaattgc
    11521 ctgatattgt ccgatttctg ataaatcgag catattgcct tccacaaatt ggatcgatgc
    11581 gtcttcttca tatgctcgct ggctggcaat catcaacatc tcttctgaaa ggtctaaccc
    11641 tgtcacttta tatccatctt ttgcaaaggc aaccgctaat gctccagtac cgcatgccag
    11701 ttccaaaata ttttttgtgt cttcttgtaa atgacgtttc gaaaaagcta accattgctg
    11761 ataaagtgtt tcgtccatca cttcatcgta aatgaaagca aatgtttcat aagccatatg
    11821 ttaatccaac cattcactaa gatcgactag cggagcatct gaccatagtt tttccagatt
    11881 atagaaattt cgttctggcg catggaaaac atgtacgatc acatctccaa gatcgatcaa
    11941 tacccatttt ccgccttctt ttccttcaat acgttttact tcatatttgt tttcttcttc
    12001 tttatcaatg atttcttctg taattgcgtt gatttgacgt tcgctatttg ctgaacagat
    12061 catgaaataa tctgccaaca aggaaacatt tcgaacgtct aaagcgataa tgtcttctgc
    12121 ccgttttgaa tctgctgctt caatcgcaat ttttaattgt tctttactat ctatgatgat
    12181 ttcctcctaa tatgagcagc ttattttttt gctacccagt aattatatgt ttcgattgtt
    12241 tttggataaa tctgttgttc ttgcgcaagc aaatgggcca atgtatgttt tgtttcaaat
    12301 gctacagctt cgtctagatc agcccatgca atggctcgtg catcttgtac cccaggaaaa
    12361 tctcgacctg gttcaatata gtctgctaca taaatgattt tgtcaaggag actcatctta
    12421 gcagccccag tcgtatgcac ccggattgca tgaagaatct ctgcatcggt gattcctaat
    12481 tcccgctcta caaacgaagc gccaacaaga ccatgccaga ttgcattatt ataattcaat
    12541 aactccggat caaaaccgtc tcttacgatt accattttga actcctcatc tggtcgttct
    12601 tttgcataat catgtgtcaa tgcagcaata ctagcttttt caggagaagc accgtatttt
    12661 ttggcaagag ccacggctgt ttcttctact ccaagcacat gcttgaagcg ttgttcgctc
    12721 attctcatct gtattttttg catcaggttt tctctagaat aagcagtata ttcattacta
    12781 tagtccatat tcatacaacc cttcattttg aatataatca attactttat ctggaacaag
    12841 gtagcggata gaacagcctt ctttgatctt ttgacgtatt ttcgtggaac tgatgtcgat
    12901 ctcaggtaca tctacccaaa ttacaggata tggagtatcc gttgtgtatc ctggtcgacg
    12961 tatacccaca aagttgacca tagaagtcag ctcatcgatt ttataccatt ttggcaaata
    13021 ttctaccata tccccaccga taataaagta ataatctgta tccggattgt tttgcgtcaa
    13081 ttccttcata gtatcatagg tgtaactttt cccaccacga gctaattcaa tcgtttcaat
    13141 ctgcaaaaaa ggattgtctt ccaccgctaa ttccaacatg ttgagtcgat gttttgcatc
    13201 aatcgtctgt ttctcatcaa catgaggtgg ctgataagaa ggcatcaaaa atacgcggtc
    13261 aagacctaaa ttccggccag cttgttcagc catcactaaa tgtgcaaggt gaacgggatt
    13321 gaatgttccg cccaagatcc ctacttgctt tttcttctct aagaattgag gcatttcttc
    13381 aggaaataat tgtgaacgaa caaatgtctt agcttgcgta ttcatcatgg tcactcctta
    13441 tattgctttt acttcttttg atagcctttg atacttttct tttgtggaag gtttgtataa
    13501 tacaataaca cgtccaatga tttggacgat ttcgcaatct atttcttttt ctaatacttg
    13561 agctgcttct tctgcaatct catctgtatt ttgaagtaac gatactttga tcagttctct
    13621 tttttctaaa gcttcttcaa tttgaacgat cattgctgaa ttgatcccac cttttccgat
    13681 ttgaaaaatc ggctgaagat gatgcgcttt gctacgtaaa aaacgctttt gttttcctct
    13741 taaactcata attttccttc ttccttaaat caatgctttg cgtttcaata catctacacc
    13801 ctttggcgcc cagcccgcaa ttactactgg cgctgttaca gtgatccagc ctagaccggc
    13861 aaaaacgatg tctgtttttt ctttcacaga aaactcaaaa cgaacaagct ccggaaatgc
    13921 ctcgacttca tcaggacgag gaggctgtaa taatccacct acatgttttt gataaaattc
    13981 gtctgctttt tccagtttcg ttcgatgaat atttacatca tttgacacat aagcaataaa
    14041 tgaagcacga ttgccgctga taaaatcaaa tcttgcaagt ccgcccaaga aaagtgtttg
    14101 cccttcattc agctgataaa ctttaggttt gatttctttt aacggtgcaa tgatccgcaa
    14161 atctttttta cctaagtagt gcgccatttg atggcgatgg ataattcccg gtgtatcaat
    14221 caaaaaatgc ccgtcatcta aaggaatctc gattttatcc aaggtcgttc ctggaaactg
    14281 cgaagttgtg attacatctt gtactcccgc tgtatttttg atgatttgat tgataagcgt
    14341 cgattttccg acatttgtta ctccgacgat atagacatcc cgtccatcgc ggtattcttc
    14401 gattttttct aatagttccg tcatctcatg agatttctta gcactagtta ataatacatc
    14461 tactggacga attcctgctt cgtaagcacg ttccttcatc cattgtgtta atttagtttt
    14521 tttcaatgat ttaggtaata tatccacttt gttcccaact aaaagtactg gattgtcacc
    14581 gacaaaacgg tgtagtcctg ggattagtga accattgaag tcaaaaatat ccaccacatt
    14641 gacgatcaat gcatcttttt gccctaattc attcagtaag cgcaaaaagt cgtcatccgt
    14701 caatgagaca tcttgggtct cattataatg gcgtaatctg aaacaacgct gacaatagac
    14761 ttccccggaa gctaaacctt tttccaaagc cgtttgcggc gtgtatccta attcaccggg
    14821 tttgtttgtt tgtataacgg caccacagcc gatacattgt aattcttctg tcattcgatt
    14881 ccacctcgcc agcccatatc agggtgtttt gctaatagat aggccataat tcttttttcc
    14941 caaaaacgat taaattgtgt cttccaacta tctgttgcga taatgggttt tacaaggatg
    15001 ctacgtatcc ctgcacgatt ggctccacgt atatcagtca taatctgatc gcctaccatt
    15061 actatctcat catctgctaa atccaattgt ttctttgcta tgttgatccc tcttgctaaa
    15121 ggtttcattg ctcgtgcaac atacaaaaga tcaaattttt caatcgctcg cgcgacacgt
    15181 tttgaattat tgtttgaaac aacaacaaca gggattcctg catttttcat ttctaaaatc
    15241 caagtaagca actcttctgt tccatctgga ttattccatg caatcaacgt attgtctaaa
    15301 tcggtcaata ctgctttgat gcctagattc tttaattggg caggtgtaat ctgatagatg
    15361 gcttctacca tccatgttgg tttgtaattt gaaaacatgc tgtctcctca tctgcaaaaa
    15421 atgaaggagc acataaagta ctcctcaacc ccgtattata ctgcatatca gcaaaaaaaa
    15481 ctacctctat actcgttcgt ctttcagaaa aagcatttct ttacaaaatg accaaaaata
    15541 aagattgatc acagaaaaat ttagaaacaa aaaacaacta atattggcgg aacctcttgt
    15601 atcgtttttc cagtaattta tgctgatcta atcgaacaag ttccgtcaat ctttcaatca
    15661 acgctttttt cataatgtgt gcgactttat atcgtggcaa ctgctcgccg ttgaacgttt
    15721 caggaataac tcgatcaacg attcctaact cgcgtagttc tggcgcagta attttcatca
    15781 actcagctgc ttctgcggcg cgactaccgt ctttccacaa aatcgacgca aatccttctg
    15841 gagaaagcac agcataaatc gtttcttcca gcatccagac ttcatccgct aaacctagag
    15901 caagggcacc gccacttcca ccttcaccaa tgatgatggc gatgatcggt acctttaaat
    15961 cagacatttc gagcagattt ctggcaatag cctctccttc gccgcgctct tctgctccta
    16021 caccgcaata tgcacctgct gtattgatca aggtaatcac cggtctattg aacttttccg
    16081 cttgtttcat cagtcgtaaa gcttttcgat agccttcagg atggggagaa ccaaaatttc
    16141 tgcggatatt ttcctgcaga tcccgtcctt tttgaatacc gatcactgtt accggtttgc
    16201 catctaatcg agcgattcca ccaacaatcg cttcgtcatc tgcaaataaa cgatcaccat
    16261 ggcattcctc gaaagaatcg aagatctctt caaaaaaatc caagcttgtc catcgttctt
    16321 tagctcttgc taactgaacg acatcatgtg ctgtcttatc cacgatctat ccatcctttc
    16381 tgtgtatgca attcaagaag cgtatggatt ttctgtttca attccatgcg gggaacaatc
    16441 tgatcgacaa aaccatgaga taataagaat tcagcctttt ggaaatcttc tggaagttcc
    16501 tgcttgatcg tctgttcgat gacgcgtctt ccagcaaaac cgatcaagct ttggggttct
    16561 gctagaataa tatcgccttc cattgcaaaa ctggcagtta ctcctccggt cgtcgggtcc
    16621 gttaaaacag ttagataaaa aagaccttca ttgctatgcc gtttgacagc agcagagatt
    16681 tttgccatct gcattagaga aaagattcct tcttgcatcc gtgcgccacc tgaagctgtg
    16741 aacaagacga ctggaagact ttcctttgtt gctcgttcga ataatctggt gatcttttct
    16801 ccgacaatcg ttcccatact tcccatgata aaattaggat ccatcactcc aataatgaag
    16861 ggaatcccct gaatggttgc tttaccagtg aggactgctt catgaagtcc tgttttatct
    16921 tgcatttttt taattttttc cgtatattcg ggaaatgcta gcggatcttt ggttacaaga
    16981 tccgtatccc attcttcaaa acttttttca tcaataatca aagctagacg ctgccatgca
    17041 ccgattcgaa aagcgtatcc gcaatgaggg catacttttt cttcaccgat gtctttcgta
    17101 taaaggatat gtttgcaatt tggacacttt gcccacatgt tatcaggaac agatggcgag
    17161 ttagcaggtt tgctctctct attaggattg atccgaatat atttcttttt cttaaacaga
    17221 gccatctatg cgcctcctat ctccgtttct ggtgtccaat tcggtaaaaa ttcttcttgt
    17281 aaaaatgctg tgctgtaatc acctgctatg actgcaggat gactaatcaa atccatctga
    17341 aattctgcgt tcgtgatgat tccttctgtg ataaattcac ttaaggctcg ctgcatcttc
    17401 attaatgctt caaaacgcgt atttccatgg acgattattt ttgcaatcat tgaatcataa
    17461 tatggcggga tcgtatatcc cgggtaaact gcactgtcta ctcgcagtcc catcccacct
    17521 gctggaagca gtaagttttg gatcttccct ggagaaggag caaaatggaa agcaggattt
    17581 tctgcattaa tccggcattc gattgcgtgt ccttggaata ctacttcttc ttgacacaca
    17641 ttcaaaggct caccggctgc tatctccacc tgttttttta ctaaatcgat tcctgtgacc
    17701 atttctgtta ctggatgttc cacttggatt cgagtattca tttccatgaa ataaaaatcg
    17761 ccttcttcat ccatcagaaa ctcgatcgtt ccggcatttt cataattgac tgctttagct
    17821 gctcgaacag cagcgtctcc tagtgcttct ctttttgttt gtgagatcac tacagaagga
    17881 gattcttcca gtactttttg attgttgcgt tgtaaagaac aatctcgctc gcctaaatga
    17941 atgacatgac caaatcgatc acctaagatc tgaacttcta tatggcgagc aggataaatg
    18001 attttttcca aatacatatc atcatttcca aatgccgctg ctgcttcttg ctgagctgaa
    18061 gaaaaatgct gtgggagctc ttcttttgat tgaactttcc gaatgccttt cccgccacca
    18121 cctgcagctg ctttcagcat cactggataa ccaattctgt ctgctatttc caatgcttct
    18181 tctactgtag ataatacacc agtacttcct ggaatgactg ggacatttgc ttcttgcatc
    18241 aattgacgcg cattgatctt atttcccatt gcatcgatcg ttgcactttt aggaccaata
    18301 aatgtgatat tgcactcttc acacatggag gcaaatcggc tattttcaga taaaaaacca
    18361 aatcctggat gaattgcttc ggcttttgtc acgattgcag cgctcagtac ttcctgaaca
    18421 ttcagatatg aatcaacggc ttttgccggg ccaatgcaga ttgcttcatc tgctaactgt
    18481 gtatgaagtg cttcggcatc tgcttctgaa tatatcgcta cggtttggat ccctagttcg
    18541 cggcatgcac gaatgatacg tacagcgatt tcaccgcggt tagctatcaa tactttagaa
    18601 aacatatttc acctatccaa tcataaaggt taattccgct tcggctactt ttttaccgtc
    18661 tactttagcg attcctttgc ctattccggc tgaagctttc actttcaata tctcaacttc
    18721 aaggtataag gtatctcccg gtgtaacttt cttacggaat tttgctttgt ccaatccgcc
    18781 gaaataagcc gtctttccct tgaattgttc aagagaaagt aatgcaactg ctcctgcttg
    18841 agccattgct tcaacaatca atacccctgg cataacaggt tcttctggaa aatgtccttg
    18901 aaaaaagggc tcattgatcg ttacattttt cttagcaacg atccgttctc cttcaaccat
    18961 ttcttccact cgatcaatca aaagcattgg ataacgatgt ggaatgattt cttttatttc
    19021 ttgtatgttc attgttttcc ctctttcctg ctttgcttat ttttgctgaa tcctaaagag
    19081 tggctgtcca tattcgacaa ctgactcgtt ttctacaagg atttctgtga tcactccgtc
    19141 ggcctcacta gttatctcat tcatcagttt catcgcttca ataatgcaga taacttctcc
    19201 tttggcaact tgatcaccta cttttttgaa agctggtttg tcgggcgctg gttgcagata
    19261 aacgattccc acgattggcg aaacaacctc gattccatca aatactgccg attctttttc
    19321 tttcattatt tctggagcag ttgttgcttg ttcagatatg acattgactg gctccgaaac
    19381 tggcaacgtt tcgtttgttt gaaccatatt catgcctcga cttgttttat ttttattcat
    19441 atacaattca aattgacctt cacgcaaatc gaattccgtt agcgaggatt gatcaaattg
    19501 actgactaat tctctgattt cattgatatc caaaattatt cctcccagcg tttcatgcac
    19561 agaaccgcat tatgtccgcc aaaccctaat gaattactca ttgcataagt aaaacttgca
    19621 ggtttgcttt cgtttttgac aactgtcaag tcaatctcag gatcttgttt ttctacattg
    19681 atcgtaggtg ggataaattg atgttctaat gccagcaaag ttgccaaggc ttcgatcccg
    19741 ccggctgctc ccaataaatg tccagtcatc gatttcgtgc tgctgacgta agtatctctg
    19801 aaattttcac ctaatgcgat ttggattgct tttgcttctg cctggtcatt ggctggtgta
    19861 cttgttccgt gagcattgat atatccgact tgttccggct gtacaccagc ttcttccatc
    19921 gcaagcttca ttgctttaga tgcaccagaa ccatctggag taggagctgt catatggtaa
    19981 gcgtcacagt ttgcaccgta tccaacgatt tctccataga ttttggcacc gcgagcttgt
    20041 gcatgttcta aagattcaag aactagaacg cctgctcctt cacccatcac aaaaccattc
    20101 cgattttcgt caaacggaat cgaaccacga ttaggatcag ttgattctga gagtgctgtt
    20161 aaagctgcaa atccagcaat ccccatctca caaatcgttg cttctgttcc tccagcaaga
    20221 atgacatcag aatagccatg tttgatgtta cggaatgctt ccccaattga attcgttccg
    20281 ctagcacaag ctgttacgat agctgtacaa ataccttttg cacctacacg caaagcaata
    20341 tttccagctg ccatgttggc aatcgccatt ggtacgaaca ttggagaaac tcgttttgta
    20401 cctttttcat gtagacgaat aacttggttt tcgattgttg gaagaccacc gatcccagat
    20461 ccgatgatga cgccaaaccg gtcttgattc attttttctt tatctaaacc gctcatctcc
    20521 attgcttcta aagcagcgta gattccatag atcgaaaaca tatccattcg tttgctatct
    20581 tttttaataa aatatttatc gtaagggaaa tctttgactt cacccgctaa ggtaatccct
    20641 gtttctgaag catcaaattt agtgatcggt gcgatgccat tcgtcccctc ttttaagcta
    20701 ttcaaaaagc tgtctgcgtc atttccaata ggtgaagtga ctccatagcc agtaattacc
    20761 actcgattca tttgtttgct ctccttttct tatccgtgca tgaccaatcc gccatcgaca
    20821 ttgatgactt gtccggtgat atatggattt tgtgctaaga aaactgctgt ttgtgcaata
    20881 tcttctactt gtccgaaacg ctgcatcgga atttgctttt ccgcttgttc cttgactttg
    20941 tctgctaaaa cttccgtcat atcagttgtg atgaatcctg gcgcaatggc attacatgta
    21001 atgcctctag ttgcagcttc tcgtgccaca gattttgtta atcctactac gccagcttta
    21061 ctagctgcat aatttgcttg accaatattt ccaatcaacc cagatacact agagagatta
    21121 atgatggccc cttctcgctg cttcatcatt tttttcaata cgtgctgcgt catattgaag
    21181 gttccaatca aattgatatc cagacatttt ttgaaatctt ctgcatccat tcgcatcaca
    21241 agtttgtcat ttgtgattcc ggcattgttt actaacacat ggatcgatcc aagcttttct
    21301 tctgcttctt tgatcatttg tcccgctttc tcataatcag agatgtcacc ggaaactcct
    21361 acgcatttta caccgaatgc ttcgatttct tctatctttt cttttggaat ctctccgcga
    21421 ccattcaaaa tgatatttgc tccagctttt gcaaaagcta aggccatcgc tttgccgatt
    21481 cctcttgtac tacctgtgat aaatacattt tttcctttta catccataac gttcctcctt
    21541 atagtattgc tattgtttca tcaaatgtct gcttattctc aacacgcaga actggtattg
    21601 ttttatcgat ttttttcata aatccgctta atacttttcc ggggccgact tcgatgactt
    21661 gttcgatgcc gattgttttt aacttatgga tactctcata gaaacgaaca ggttgcatga
    21721 cttgctgttc aagtagtccc gcgattgttt ctttcttcat tatttccgtt gttgtgttgc
    21781 ttatgatagg aaaagaaggt tcagagaatt gaatctgact taggtccttc gccagttttt
    21841 ttgctgccgg ttctaaaata gctgtatgaa aaggcccgct gacatttaga gggatcattc
    21901 ttttgaaccc tttttctttt aatagtaaaa cagcttcgtc tactgctttt tcttcgccac
    21961 caatcacgat ctgctgaggt gtattataat ttgcaggaga tacgatgccg tacttgctag
    22021 cttcatgaca gctttcctcg atcgtttcaa tcggcgcatt catcactgca accattttcc
    22081 cgcttccagc tggggtagct tctgtcatat aagcgcctct ttttgctact aacgcaactg
    22141 cttcagtgaa ggatagcgca ttactagcta ctaatgccga atattctcct aaactcagtc
    22201 ctaaagctgc atctgggatg attccatgct ccttcaataa gcgataatac gcgatgctga
    22261 ctgttagaat agctggctgt gtatattgcg tctgatccaa acgttcattt tctgtaaagc
    22321 aaagttcagc catatcgtag ccgagaatct cacttgcttc atcaaatgtc tgctttacaa
    22381 cggcttcttc atataaatct tttcccatac cttgatattg tgcaccttgg ccactaaata
    22441 agaatgctgt tttcatgttt ttctccaata tatccagaat atatgtttga ttcttcctat
    22501 tcaaaaaggc cgagacattc ctatttcagg aaatgtccca gcccccaacc taattttaat
    22561 gattatgcag tttgtttttc tacgtaagtc actaaatctt gaaccgtttt gattccgtct
    22621 tctgtttcga ttttcacgtc aaattcatct tcaatttcat tgatgatttg gaataaatcc
    22681 aagctgtcag cttctaagtc ttcttggatg tcagtagtca atttgatttc ttcagtttct
    22741 tttcctaatt cttctgcgat gatttcttga attttttcga ataccataat aatatattcc
    22801 tccgatattg tttgcttttt atttttataa tttaacagtc tacaactcca tgagaatact
    22861 tccccatgtt aaacctccgc catagcctgt aaatattact ttctgctgtt ttcctaaggt
    22921 gatctttcca ctagaaactg cttcatccaa taagataggg atgcttgcag cagatgtatt
    22981 cccatattta tccatattgg tcaggaactt ttcttgcggc atctttactt ttcgggcaat
    23041 tttctcaata attctgaggt ttgcctgatg caaaagcaga taatcaactg gtttgtcttt
    23101 catgacttct tggatattgt ttgcaacgtc tcgtacggca aaatcaaaaa tatctctgcc
    23161 agtcatttgc aaataatacg aaccttctga atcttctgaa tagaacggat ttttattttg
    23221 ctggtagcca gcggtcaatg agctacttct ggtaccgtca gctgctaatt tttctttcag
    23281 caattttttc tgtggattcg cttctaagag aatcccacct gctccatcgc caaacaacac
    23341 agcagtcgta cgatcagacc aatcgattag cttagatagt gtttcaccac caatcaccag
    23401 tcccttagtt gagccgcagc ggatcatttt ttcagccatg cttaacgcat aaacaaatcc
    23461 tgagcacgca gcactgatat caaaagcgat agcatgagtt gctcccaatt tcccttgtac
    23521 ttgtgctgct acagatggtg tcgtgtaatc gggcgacatt gttgctacta aaataaaatc
    23581 caaatcttta gggtttagat ttttctgttt tatcaatttt tccgccacta aaatgcataa
    23641 atcagaagtc tcctgatttg ttacacatct tcgttcacga atacccgtcc ttgacgaaat
    23701 ccattcatca gaggtatcca tcatcttgga aagatcatta ttagtaataa tcttttcagg
    23761 aaggacgctg gctgttgcag taatcattcc aaattgttcc attaaatatc ctcacttata
    23821 gtcttgcaag aagtcgtgca agtttttcag tgcatccagc aaggcatgct gttcctccgt
    23881 agccattccg tctaagatgt tcttgaccat ttcacgatga aaatgctgat ggacccgaaa
    23941 tagtaacttt ccttttttcg ttagtcccaa ctttacaacg cggcggtcat cttcactgcg
    24001 gatacgttcg acatagcctt tttttactaa cttgttaata gcagtggtca aggtcccaac
    24061 agtaattgat agttctttgg ctacttctga agttgttttt ttcttgtaca tcccgattgc
    24121 ctcgatcgtg tgcatctctg tgattgacag atctttgaat tgagattttt tcagctcaga
    24181 ctcttcgatt gtcaaaatat cattgaagac actaacaaga taatcattta ctgtttttaa
    24241 atctggttcc atgttccacc gtccactaat tagtttgatt atcaaatctt ttgatgttca
    24301 aactatatct taactttttt caaaatgcaa ccttaaaaga tcattttttt actatatgag
    24361 ctttttttaa
//
LOCUS       DACDAF010000037        24272 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.037, whole genome shotgun sequence.
ACCESSION   DACDAF010000037 DACDAF010000000
VERSION     DACDAF010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 24272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.037"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..572
                     /locus_tag="IVZ69_001387"
     CDS             <1..572
                     /locus_tag="IVZ69_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP8183478.1"
                     /translation="ASRIAIMSEGRVIQFDTPENILRHPANDFVEELIGEDRLLQAKP
                     NATRVGEVMLNTAITITPEKSLQEAIKLMREKRVDTLLVTDNSNVLKGFIDVETLNKK
                     RGKVSSVGDILNKHVFYVKESAYLRDTLQRILKRGLKYVPVVDEQNKVVGILTRASLV
                     DIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            576..1217
                     /locus_tag="IVZ69_001388"
     CDS             576..1217
                     /locus_tag="IVZ69_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183479.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            1214..2131
                     /locus_tag="IVZ69_001389"
     CDS             1214..2131
                     /locus_tag="IVZ69_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP8183480.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            2128..2799
                     /locus_tag="IVZ69_001390"
     CDS             2128..2799
                     /locus_tag="IVZ69_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183481.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(3340..3828)
                     /locus_tag="IVZ69_001391"
     CDS             complement(3340..3828)
                     /locus_tag="IVZ69_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HAP8183482.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(4029..4295)
                     /locus_tag="IVZ69_001392"
     CDS             complement(4029..4295)
                     /locus_tag="IVZ69_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP8183483.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(4295..4558)
                     /locus_tag="IVZ69_001393"
     CDS             complement(4295..4558)
                     /locus_tag="IVZ69_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP8183484.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            complement(4551..4823)
                     /locus_tag="IVZ69_001394"
     CDS             complement(4551..4823)
                     /locus_tag="IVZ69_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183485.1"
                     /translation="MYWCCCIDSQALDSTFAKDDTLLPITLRLATASRKGVRSERGQR
                     SSLKRGLFLYVKKRKSLLNLSALLYFFDVLNQVRYNYIRKRRRDNG"
     gene            5034..5219
                     /locus_tag="IVZ69_001395"
     CDS             5034..5219
                     /locus_tag="IVZ69_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8183486.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(5361..7184)
                     /locus_tag="IVZ69_001396"
     CDS             complement(5361..7184)
                     /locus_tag="IVZ69_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HAP8183487.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(7782..10487)
                     /locus_tag="IVZ69_001397"
     CDS             complement(7782..10487)
                     /locus_tag="IVZ69_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HAP8183488.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(10793..11740)
                     /locus_tag="IVZ69_001398"
     CDS             complement(10793..11740)
                     /locus_tag="IVZ69_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HAP8183489.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            11930..12199
                     /gene="rpsN"
                     /locus_tag="IVZ69_001399"
     CDS             11930..12199
                     /gene="rpsN"
                     /locus_tag="IVZ69_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HAP8183490.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLHKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(12375..12737)
                     /locus_tag="IVZ69_001400"
     CDS             complement(12375..12737)
                     /locus_tag="IVZ69_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP8183491.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(12748..13869)
                     /locus_tag="IVZ69_001401"
     CDS             complement(12748..13869)
                     /locus_tag="IVZ69_001401"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HAP8183492.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(13885..14235)
                     /locus_tag="IVZ69_001402"
     CDS             complement(13885..14235)
                     /locus_tag="IVZ69_001402"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HAP8183493.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(14365..15876)
                     /locus_tag="IVZ69_001403"
     CDS             complement(14365..15876)
                     /locus_tag="IVZ69_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HAP8183494.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(16198..17550)
                     /locus_tag="IVZ69_001404"
     CDS             complement(16198..17550)
                     /locus_tag="IVZ69_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HAP8183495.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(17703..18779)
                     /locus_tag="IVZ69_001405"
     CDS             complement(17703..18779)
                     /locus_tag="IVZ69_001405"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HAP8183496.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            18975..20720
                     /locus_tag="IVZ69_001406"
     CDS             18975..20720
                     /locus_tag="IVZ69_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HAP8183497.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(21000..21437)
                     /locus_tag="IVZ69_001407"
     CDS             complement(21000..21437)
                     /locus_tag="IVZ69_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HAP8183498.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(21421..22794)
                     /locus_tag="IVZ69_001408"
     CDS             complement(21421..22794)
                     /locus_tag="IVZ69_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183499.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(23116..23604)
                     /locus_tag="IVZ69_001409"
     CDS             complement(23116..23604)
                     /locus_tag="IVZ69_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8183500.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(23626..24228)
                     /locus_tag="IVZ69_001410"
     CDS             complement(23626..24228)
                     /locus_tag="IVZ69_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP8183501.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         6960 a         5163 c         4487 g         7662 t
ORIGIN      
        1 tagcaagccg tatcgccatc atgagtgaag gccgtgtgat ccaatttgat acaccagaaa
       61 atattttacg tcatcctgca aacgatttcg tagaagagtt gattggagaa gatcgcctac
      121 tacaagccaa gccaaatgcg acaagagtcg gcgaagttat gctaaataca gcaatcacga
      181 ttacaccgga aaaatcatta caagaagcaa tcaaactgat gagggaaaaa cgtgtagata
      241 cgttgttagt taccgataat tcgaatgtat taaaaggatt tatcgatgta gaaacgttga
      301 ataaaaaacg aggaaaagta tccagtgtcg gcgacatttt gaataaacat gttttttacg
      361 taaaagaatc cgcctatctt cgtgatacct tgcaacgcat tttaaaacgc gggctgaaat
      421 acgtgccggt cgttgatgaa cagaacaaag tcgtaggtat cctgactcgt gcatcattag
      481 tggatatcgt ctacgatgtg atttggggag aagatcccgc aactactgat gttgcagagt
      541 cagctactcc tgaagaatct aaggaggtct gacctatgca gcagtttttt catcagcacg
      601 gttcagaaat tctctcaaaa ggttttgaac atctttatat ttcaggactt gctttgatca
      661 ttggtatcat cattgctgta ccgcttggtg tcttactgac acgttttcca aaagctgcca
      721 cgattgtgat tggcttaacc agtgccttgc agacaatccc ttctcttgct ttattggcat
      781 tgatgatccc gctatttggc gtaggtaaat tacctgcgat tatcgcactc tttatttatt
      841 cattattgcc gattttacgt aatacgtaca ttgggatgaa aaatgtcgat tggaattatc
      901 gggatgtggc aaaaggcatg gggatgactg agttccaatc cattttttcc gttgaattgc
      961 ccattgctat gccaacgatc atggctggta ttcgtttagc tgccgtttac gtgattgcat
     1021 gggctacact tgcctcttat atcggcgctg gtggtttagg cgatttgatt tttagtggac
     1081 tgaataatta ccaaccagat ctcattttgg caggtacgat ccctgtaaca attttagcac
     1141 tattggctga ttggcttcta ggtctcttgg aacaccggct gacaccgatc gcacttagag
     1201 aggagaatga agaatgaaac gtatactaaa aatgaccatg gttcttttct ctcttcttat
     1261 acttgcgagt tgttccttcc ctggtcttgc cagcaataca gatgaagaca ccatttcgat
     1321 cacaggtgga atcacttcag aagcacagat cttagcaagt ctagttgccg gaatggttga
     1381 acattataca gataaaaata ccgcaatcat caacaatctg gctactacaa ctatcaacca
     1441 tcaagcgatg atgaacggag atgcttcaat ttcagcggct cgctacacag gaacagattt
     1501 aacgactaca ttgaaccttc ctcctgaaaa agatccgaaa aaagcgtttg ctaccgtgaa
     1561 agatgaattt gagaaaagat acggtcaaac gtggttcccg tcctatggtt ttgaaaatac
     1621 gtatgtcttt cttgttcgaa aagacaccgc acaaaaatac catctatcta aagtcagcga
     1681 tctgaaaaat gtagcggatg aattagtagc tggtgtagat acttcttgga tcaatcgtaa
     1741 aggagacggt tatgacggct tccaagaaac ttatggcttc tccttcaatt cgatattacc
     1801 tatgcagatt ggacttgttt atgacgcagt cgaagcagga aaaatggata ttgttcttgg
     1861 ctactctacg gatggacgga tcgccagtta tgatctagtc atgttggaag atgatcgtca
     1921 attcttccca ccatatgatg ctgctccagt tgtagacaac aagatattag ctgatacgcc
     1981 tcatttaaaa gaagccttaa ataagttagg tcataccatc agtacggaaa aaatgcagga
     2041 attgaactac gaagcagata ataatctagt ggaaccatca gtagtagcac aacgtttctt
     2101 acaagaaaac cactattttg aagggaagtg aagcaattgg ataaaatgaa tgtctttcaa
     2161 caatttttct attatttcca ggaaaatggc tcctatatct ttgcacaatt tatccgtcac
     2221 ttcctgattt ctatctatgg tgtcctcttt gcagcagttg tcgggattcc ggttgggatc
     2281 atgatttcta ggagacgtaa attagcaaac tgggtgattc gtttggcgaa tatcatccag
     2341 acgatccctt ctctagccat gatctccatt ttaatcattg gattaggcct gggagtcaat
     2401 gtcgtgattg ttactgtatt tttgtattcc ctcttaccga tcatcaagaa tacgtatacc
     2461 gggatgatcc aagtagacaa aaacatcctt gatgtcggca aaggcatggg gatgactgct
     2521 agacaacgac tattcatggt agagttacca ctctctgttt ctgttatcat ggcaggcata
     2581 agaaacgcgt tagttgttgc catcgggata accgcgatcg gtgcattcgt cggtgctggt
     2641 ggtcttggag atatcattat ccgaggaacc aatgcaacag agggcacatc gattatttta
     2701 gcaggtgcat tgccaactgc attaatggcg atcatcacgg actggctttt aggtattttg
     2761 gaaagacggc tagatccagc cagccgtaca tcacgctgat gttattgtaa aaaacaaaag
     2821 cttctgcgac catttgttgg tcgcaaaggc ttttttagtt ctgtcatttt taaggcaata
     2881 atccactctg attcttccct ccttatgggc aaagagttgc ttttcttagc tatttatcca
     2941 ttccgtatac tccaacttca tactgccaac gggttcatat ctgcatccac cgactaagtt
     3001 tttttcttat ccgctaaggc attttgccaa tccattttcc catcactcgt catggaattc
     3061 ataccacatg atctctaaat actcgtctgc ttgttctttg aattgggcat caattcttac
     3121 atcctttggc gtggctttca tttaagcctt ttccatcagt cctcgattgt tcgatgcctt
     3181 cagctgcatc atcaaaactg gtgactgccg tatcggtaac ttcgatcatc ttttatacaa
     3241 tcgggaactt gccatcctca tccttggcta aaaacatatc tagccattcc agcttctcgc
     3301 catgggaggt ttgcggttcc taaaaccggt acacgattct tatggactgc atccgtcgca
     3361 actagacttg gcgatacgat gatccttcac cagaagagca cccccgtaaa ccaattgatc
     3421 gatatattgc caataagaaa agacattggc gtaaaagata tcgatccctc gtgatgcatt
     3481 gccgttgata ctgctattca tggccgaaag cgccacgact ttaacttctt ccgtttgagt
     3541 gacattcatg ttcggcaatg tcgctttgga tacccgctct gctaaaggaa cgacactggt
     3601 attgtatttc gtatctgtat cttttccaaa agaccatgcc aacgaatcct ctgggaacca
     3661 ataagacgac tccggttgat tgtccattgc ttttttcaac atacttttgg ctgtttctcg
     3721 ataaacgaca tttccaattg tcttcgcctc actttggcga taatcgatgg tcgttgccac
     3781 tgccaacact aacaacgatg ctccaatttt actgattttc cttgtcacac ttcttcctcc
     3841 ttgttttaca taaacccgtc aacattccat tcctaaactc aaacaatgac ccttcaaagg
     3901 tggagatata ggaacaaatt aaagaaatca tgcaataaat ccaagaaggt tggttttaga
     3961 acaaaaaaag agtctccttt ttggggagac tctttgttaa ctatctaaaa aggttggctc
     4021 ttctcacttc actcataatg tgtccaggca gaataaattt ctacaacttt attttcctca
     4081 tcaactttgt aaaccactcg atgctgtcta ttcagcctgc gtgagtatct gccttcatgt
     4141 gtaggtctca gcttttcaaa agactgcgtg ggcatatatg gatcttcctt caatgtctga
     4201 atcacttctt caaattgttt ctttaaattc gtttgcttga tttttcttaa atccactttc
     4261 gcagagtttt tgattgcgac tgtatagtta ctcatcaaag agcttcccaa tcaatatcat
     4321 cgatattcgt aaagctactg tcgtcttttt cgcggtctcg tactttatct aaagtacctg
     4381 tttgctcaag aaaaagggtt tcttgaatcg ctctccagtc ttccagccca atcaatacag
     4441 cattgtttcc actacgatca ctaataatct cgatttcagt atgattttca tttacctctt
     4501 tcaataactg ataaaaattt ttacgagcag tgctaggatt catcgttgta ttagccattg
     4561 tctctcctcc tttttctgat ataattatag cgtacttgat taagtacgtc aaaaaaatac
     4621 aataaagcac ttaaattcag caaacttttc ctctttttta catagagaaa aagacccctt
     4681 tttagggagg atctttgtcc acgctcactt cttactcctt tacgactagc ggtagccaaa
     4741 cgtaaagtaa ttggtaacaa cgtatcatct ttagcaaagg tcgaatccaa agcctgtgag
     4801 tctatgcaac aacaccaata cacgaaggtt cctcgttgca gtgtgacttg attgatatct
     4861 tgaataacct gaggatacgc acgaaagatt tgtaacggtt attcaaaact gattttggcc
     4921 gtcaagtctt ctactgcctc aaaaatgatt gcctctttcg tctcctgtca ttcatgttca
     4981 ctatcgattt gatacttgct tagaccgttg ggtttgtgaa tcaccaatta aaaatggcac
     5041 tgagttatgg taacaaaaaa tggtcacttg acgaggctga gattcctact tatgaagaca
     5101 catggcactt aagagtcgag gtaaaggaag aagctgaaaa tataggaggc tgtacattat
     5161 ttggcaaagg attcggaaat tatgatcaag acatcaaaat caaaatgttt tacagctaaa
     5221 taggaagaat aataacattt catacgctgt tcccatcttt aatggcttat agagggcacc
     5281 tttagctgag aataagacaa aacagaccct ctagcttcaa ttaagagcta gagggtctgt
     5341 ttttgatttt aaaacttggt ttatttcttc aaatggtagc tataggtgct gacaacgata
     5401 ttttcacgcc aagacaatcg caatcttaac cgcaaacttg tttggttatg gagaatattc
     5461 tgccagcgtc tgtttggtac aaattgagga atcaacacag tagttgtata gttttgtttc
     5521 gctgcatttt tacttacgat atctacataa cggataattg gattttcaat cgagcgataa
     5581 gaagagtgga cgattgaaaa acggacatct gggaaatgct ttttaaattc tgcttcgatt
     5641 tctttttctt tttcgacatc ttcgtctagc gaaacatgca tcgcaacgac ataatcaccg
     5701 atcgaacgtg cgtaattcaa cgcaccgata tttacccgtg tcacattccc gactaataca
     5761 agaacggtat tcccgtcata atcatgtagt tttgcatcat tttctaaacg aagctgttct
     5821 gctacttttt tataatgatc atggatctta taaaaaatga acataacgat tggcataatg
     5881 atgaagaaag gccaaatgtc ccctaaccga tagacaaaca aaatcgcaat gattgcatat
     5941 gagatgaacg cacccgtaat attggcaatc gatttgctta accatctttt tccttctttt
     6001 ttccatttga cgaccatccc tgtttgagat aaagcaaatg gaatgaacac gccgatagag
     6061 tataacggaa tcaagcgttc tgttgagcca tggaaaataa acagcaatac gatcgaacct
     6121 agcgctagtg tgataatccc attggaatag cctagtcgat ccccacgatc ttgatacatg
     6181 tgaggcatga atttatcttt tgccagattg tatgcaagaa ctggaaaagc agaaaaaccg
     6241 gtgttagcag caactgctaa aatcagcgct gtagcaaatt gaaggacgta atacaaaata
     6301 ccatgtccaa agacagcttt accaatttga gacaaaacag tgacttcttt ttcaggaacg
     6361 atcccatacc aatagttgat aaatgtgatc cccacgaaga agaaacctaa gatcaatgcc
     6421 atcatcgtca atgtagcagc ggcatttttt gctcttggct tcttaaagaa tggtacagca
     6481 ttactaatcg cctccacccc agttaaagag gaagaaccag aagaaaatgc tcgtaaaatc
     6541 aaagcgatag aaacacccgg cacagccgct cctggaagtg cagtagcttg caatggcaca
     6601 gcacctgtca cgatattata taaaccaaca acgatcagta acgagatcac aaggataaat
     6661 gtgtacaccg gaaataatag gaacgatgca gattccctca gcccacgaag attcagcatc
     6721 atcagtagca aaacgattgt cacagaaata gcgacttgat gaccgtagag tgctggcacc
     6781 gctgatgtga tcgcttcagc acctgctgag acagatactg ctactgtcaa catgtagtcg
     6841 atcaataaag agccaccgga aatcaagcca gcattctttc caagattctc actgctgacg
     6901 acatatgctc ccccgccatg aggataagca tggatgattt gacgatatga tagcgttaat
     6961 gaaatcaata aaataataac aaaagcggca atgggtagcg aataccagat ggctgcagca
     7021 gacaaagcga ctaaaacgac aacgatttgt tccgtaccat atgcaataga tgataacgca
     7081 tcagacgaca ataatgccaa agcagcaaat cgggttaatt tgtgctcatc attttcagca
     7141 gattttaaag gcttacctac taacaacctt tttaagtaat ccaatttcta aactccttta
     7201 cacacaattt tacttcaagt tttatagtcg aaaatttata gtaaacaaga tgttatagta
     7261 cgctcactga ccttaaaagt caataaactt taagaaaata attggaaaaa aacagaaaaa
     7321 tatcaagcgc tttttcaaac gctttaatac agcaaaaatc taacattttt ttatgggctt
     7381 tttctttgaa ttctataata aaaggataga acttgactta gaaaatcaag ttctatcctt
     7441 tttgatatct taacttttgg aagagagatg taaggctgct ttctacccat cattcttact
     7501 actcgaagca tagcgcagtt gtcacaacct cttgataaac ggtgtttaaa agcttgcatc
     7561 tgcggtaata agctcaacca aattaaaaac ataagaagct gtttttattt ggtcgttctt
     7621 attacttgat gcagagcagc ttttttacaa cctcttggta cacggtgttc aatcagctga
     7681 ccctcggtat tagctcaaaa aaacggcaaa atatgaggaa ctatttttcc atttttttct
     7741 ctaatactca ggtcaaaaca ctgatttcac aacctctttt tttaatgaaa aatatggctc
     7801 tcatgcgccg cttctttgaa tttcgtcatt ttttcttcga tgaacggata gattgccgtt
     7861 cctacgattc caaagacaac aaacaaaccg atcatgatcc agattgcttt cgtagcattt
     7921 ggccaataaa ttcctcctgc agattcccgt aacaagttta ccgcatgagt aaatggcaag
     7981 aacggattga tcatttggaa gaatttccct gagacttgga tcggatagtt cccgcctccg
     8041 ccagagatcg acagtactaa gatgataata gcgatccctt taccgacatt atcgaataat
     8101 gcagccaaga catagacgat catcatgaac gctaaggcga tcaagacagc aaatgacacg
     8161 ctgtagaccg gattttggac atctactcct agtaagaaaa tattccctaa tgtaacgatc
     8221 aagctttgcg caatcgccat tgtcaaaaat gtcagcatac gagcaacgaa ttgttctcgt
     8281 ttcgtaaaat tgtttcggtc tttctttcct aaatagtatt ctgtcgtagc aacacttgaa
     8341 agaagaacag cgccgaccca cagacatagt gcagtataaa acggggtgct agctgaaccg
     8401 ttatttgcga ttggataaag cgcattggtt tgtagctcaa caggttgtgt aaagaagtca
     8461 ctttcttttg ttgcgtctag tttcaataat ttgatgactt cgcctagatc gacttcttgt
     8521 tcgccttttc ggatcgcgtc tgctgctttt tggataccag ctttgatatt tggccagtca
     8581 ttgttgatca agtccgcagc agcgttcaca gctgtttcga cttctggcat tttttcattt
     8641 actgttgtca atgtaccggt gatttcattt tttagtgctg gccaatcatt ttggataaaa
     8701 tcagcggcca atcctaattt ttgctgaatg atcggtaatt cattgttgta taggtctgcc
     8761 ccttcattga tgccattgac gatggtatcc atatttccat tcagcattgt attggcatca
     8821 tggatttctt gtccaattgc aggcatttct ttttgatatt tttctaaaat tgccactgca
     8881 ttcgttacag ttgctttcgt tgagctgaga agcgaatcaa agtcgatctg gtccgctttg
     8941 ctcagtgcgc cttgtgcagt cccaatcgta tcgatgactt ggtctagtag agaagtgaca
     9001 gtggaactga tttgacctgt attgatacca gcaatgatgc cattgatatt attaacaacg
     9061 gcatcaattt gatctagcaa ttcatcaata gccttcgtgt cttcattttg aacagctgtg
     9121 ttcaaagcag ataggcggtt ttgcagattg cttagcaagg gttttaattg atttagctga
     9181 tcaataattg gctgtaattt cgtatttcca gcacttgttt gcaatttagt caggaactcg
     9241 accagtttat cgattgcatt ttgttgttga gatattccgt caataaagcc gttcaataca
     9301 ttgctgatgt ttttcttttc atcatcagtc agcttaccat cttcaatagc tgttcttaca
     9361 gtatctatta acgaacctgt cgttgttgcc acttgtccaa ttgacttcaa tgtaacatct
     9421 acactgtttg tgatgcttgg tatcgcatct ttcagctgag aggcacctga ttttgtttgg
     9481 tttgctagat cacttgcctg attttctaaa tttttcacat ctggcaagat atcttgtact
     9541 tgttggatga tcgtcaagcc ttgttttgct tcatcgattc cttggttcat tgtctcttgg
     9601 atcgaagcaa aatcgccgtc gatctctgct agttgcttac cggcattttg gatctctggg
     9661 attttttctt gcaaatcaag gatgattttt gcttgatctt tcaactcagg cattttgtca
     9721 ttcaatgcaa cgactttttc acccatctca tctactttag ggatgtaatc cacgaattca
     9781 tttgctttat tcagtttttc cttgatttca ggtagttgac tttgtaattc gaggacttgt
     9841 tttgtgtagc cgtcgatcgt gtccaaattt tcatctgttg ataaaatcat atctttaact
     9901 ttattgatac ttactaggtt cgtatcgatg tcgtaaccta tctcattgaa tactttcaat
     9961 aaagtcgaac tggctgtttt gataaattca tttgtgattt gcgattggat cgaacttgct
    10021 cctttatcgg tgattttcgg tgcaatcgca ttgatttttt catttaccgt atattcgatt
    10081 tttggtttct tgatatcacc actagtaaaa ctcagcagat cttctgagaa atcctttggc
    10141 aagtaaatac ctgcgtaata ctttccggaa cggactccgt cttctaattg ttcttttgaa
    10201 tcaacgaatt gccatcctaa ttgtttattt ttatgaagcg attcgatgac ttgctcccca
    10261 atggccactt ctttaccttg aaactctgct ggcttgtctg cactgtaaac agcaattggc
    10321 agctctccag tatttccata tggatcccat aatgctttga tgttaaacca cgcatatagc
    10381 gaagggatga tcatgatcgc gatgatcaga agtgttgcaa tcgggttttt gaaaatccgt
    10441 ttccagtcaa gcaaatataa tcgaagcgta tttttgattg actgcatagt tctccccctt
    10501 cttctttttt cagctgaatt actttaccat gtatttcata cttttttcaa tcggcttttt
    10561 tcaaaaaagt cgaatttttg gacatatcac ggcaattgtc tcattgtaat ctcttacata
    10621 ttgagaaata attaaggatt acagccttta ctttatcatg aaataaaagg gaaagataat
    10681 tttatgccaa agtttttatc tattatacgt atacgcaaaa aagctaaaac attttttgtc
    10741 tttgccccta caaaaatgtt tcagcttttt tcgtttttta ttcctgtatt tcttattttt
    10801 cgaatgacag gatgattttc ccagcaggag gatgtccttc aactagctga tgtgcttgga
    10861 tgacatgctt aagtgaagca gacagattca ttgaaataaa aacatgaaag gctccttttt
    10921 ggtaggcttt gattatgcca gcaaaggctt ctgcatctag atattccttt cttggaacaa
    10981 acgattcata aaagccttcc tttttttgcc gcaaatctag atctgggagg tcatttaatg
    11041 caacatacct gccgcctggt ttcatgatct ggatgccggt ttctcctttg atacttcctt
    11101 tcgtcgcatc gattacaagg tctgcctgat cagcaaattg cagacctgga tttgttttat
    11161 cataagcagc aaatgctgaa gctcctaatt tttttacctt ttcctcattt ttactggatg
    11221 cactggttaa gattcggatt cccttttcat ggagaagctg gatcagactt gacccgaccg
    11281 cacctgatgc tcctagtatc attacagtat ctgtcggctg gatttccgtc aaatggttga
    11341 ttagattata agccgtaatt cctggcgtga ccattccggc tgcttcttcc caactcattt
    11401 tatctggaat ttttgctact tttgctgatg gcaacacgac ttcttctccg taagtcccgc
    11461 cgactgcatg gacagctact cgatcaccta catgaacagt tgtgacatct gaaccaatct
    11521 ctgtcacaat accagcgcca tcattacctg gtacataagg gaatttcaat gttcgtatct
    11581 ctttcatttc tcctaaacgc aaggcaacat cataaggatt cacactgaat gcttttattt
    11641 ctacacgaac atgtccagaa ccgacttctc tgggatgagc atcgatttct tcaaaaacat
    11701 cttgtgcttc tccgtaaccg ttaattgcaa atcttcgcat ggtcaccatc tccctttttc
    11761 tttaagttta cgtttatgtc tttattttga caaaaaaaat gtcttttcgt tttggcgcat
    11821 gattcaaaac aaaatagttg tcttttttcg cgtaacgtgt taaattattt atctaaaagc
    11881 gtaaagatta cgatttacgc taataaaaaa taattggagg aatttgttga tggctaaaaa
    11941 atcaaagatt gccaaagcaa aaaaacagca agaaacgatt gaacgctatg ctgctttacg
    12001 ccaggaatta aaagcgcaaa aagattacga aggcttgcat aaacttcctt tagatgctcg
    12061 tccagaacga ttgaaaaatc gtgatttaat cgatggacgc cctcgcggat acatgcgtaa
    12121 attcgggatg tcccgtataa aattccgtga attagcacat aaaggtttga ttccaggagt
    12181 aaaaaaagcc agctggtaat ccaagtctgg ctgtaatgta aaggaggagg gcgcatggac
    12241 cactccttgg atcatcaaaa aagatacgtt cgcttcttct agcagaaatg ctggtactag
    12301 aagcagacgt atcttttttt acgcacagct ggtccttttt tatatgtaaa ggctgcatgg
    12361 ttacttcgct atatttattt agtaacagga gtcagtgctt cgatacccac actaattttc
    12421 aatgctcggt caacttctgc cataatgggt cgatccaaat ggcagacctt ttctttcaat
    12481 cttgatttat cgatcgttct gatctgctcc aacaggataa cggagtctct ttctattcct
    12541 gttccagtag ctttgatccc aatgtgagtc ggaagcttag gtttagccat ttttgccgtt
    12601 atggccgcaa caatgatcgt cgggctaaaa tggttaccta gattattttg aataaccaaa
    12661 actgggcgtg ttccgccttg ctccgatccc acgactggag aaagatcagc aaaataaata
    12721 tctcctcttt ttaccatagg atcctcctta ttcttgatat tctcttggta tccgctgtcc
    12781 taatccgcaa gccacttcat agtggatcgt acctaattga tctgctatat cctgcatagt
    12841 gatttctttg tctgcatttt tgccgataag cgtcactttt gttccgacag gaaattcttg
    12901 aggcaatcgg atcatcagtt gatccataca tacacgccca atcgtttcac agtagttccc
    12961 ttctaccaat agagaaaaac cctgcatctt tcgtggccag ccatctgcat aaccgatcgg
    13021 tatcgttccg atccactctg cttcaggagt gatatatgtt tctccatagc cgattccttc
    13081 acctgctggg agttttttga cttgaatcaa ttcagaaacc agctcaagtg ctggctgcaa
    13141 tggataaact tccggtagtg cgtgcccaga gggattaagt ccgtacattg ctactccata
    13201 acgaatcata ttgccgattg tttcatcatg ccataaagcc gttgcactat tgctgacatg
    13261 tacatatcga ggaagttcgg gaagtttttt cagcacttct ataaagcgtt ctttttgcag
    13321 attccaatat gtatcatctg cctgatctgc tgtagaaaaa tgggtaaata aaccttccca
    13381 ttctaataca cgactttctt tgatgaatgc agctgcctct tttacttctt caggtgtaca
    13441 aaatccgata cgacccatcc cagtgtctgc ttttagatga atcgaaagag gcgtctctag
    13501 cttacttttc tctaaaacag cagctgctgc ttgcaaccat tcccgtgtac ctgcagttac
    13561 tgataaatca tgagcaacag ctacagtcag tgcgtcgtaa ggaaccatat tcaagataag
    13621 gatgggctga gtaaatccag cttctctcaa ctcgactcct tcatctaaat ttgaaacaca
    13681 aaagcccgaa gctccacctg caactgctgc ctcagctgtt tcaatagctc catgaccgta
    13741 tccgttcgct tttactactg caaacaattc ttttccttgc ggaagtcttg caacttcatt
    13801 tgctacattt tcagttatag cttttttatg tatcactgct ttcgttgggc ggtgccaagc
    13861 gacaaccatc gtttttcctt ctttctagtc ttccaaaata atttgtgcaa aagctgtttc
    13921 atttgtatga gtaatactga cccatacatt gccttcatga ggtgaacgcg tcacaacagg
    13981 ctgaccattt tcatttttta aaatctcgac atcttgaaag gtaacttttc cgatcccagt
    14041 tccccaagct ttagagaaag cctctttgca agcgtaacgc ccgcctaaaa attctacttg
    14101 gcgatgaaaa ggcaaggact ggaatagttt catttcatca gaggtcaaga ttcgtgcaat
    14161 gaattttggt ttttcttcga tcagccgagt gatcctagga agttcgactg catcgatccc
    14221 aattcctttt atcatatgct tttctctttt caataaattt agaacactct cattctacca
    14281 aattataacc attttgccac aaataagtcc acaaataaca aaaatgaaag tttctcttaa
    14341 aaaagagaaa ctttcatttt atgtttaatc gttatttgaa cggattacaa atccgcgttt
    14401 tttatcattg tgacgtttac cgccatcttt ttggctgtta ttatttttgc tataaccgcc
    14461 ttttgatttg tttccacgat aattaccgcc gtcacgacga ttacggttgt ttccgccacc
    14521 acgtttgcca tttttattgt atcctttttt ctgcattggc aatgggcgtt ctggtgtgat
    14581 cttcactggc actgcatcag ctggatcttt tgctgtcgtt tttagcaaaa gtgcaactaa
    14641 atcttgtgca gaatattctt ctaataattt atctgctgtt tgcaggtatt tatctagacc
    14701 attttctgca agttttgttt cgatttgttc aactgcagca cctaattgac ctttgaatgc
    14761 ttctttttcg gttggtggac gtaaagtcgt catccgtttt ttcgtcaagt tttcaatcac
    14821 atgcaagtag tccatttcat ttggtgtaac gaaagtcaca gacataccgc cttttccggc
    14881 acggcctgta cgtccgatac ggtgaacgta gctttctgga tcttgaggga tatcatagtt
    14941 gtacacatga gtgacacctg aaatatctaa tccacgtgca gcaacgtctg tcgctacaag
    15001 gatatctaaa tgaccgctct taaatgaacg caatacgctc attcgttttt gttgagacaa
    15061 atcgccatgg attccttctg cacggtaacc gcgtgcttct aatccgcgtg ccaattcgtc
    15121 tacacggcgt tttgtacgtc cgaagacgat tgttaattca ggtgtttgaa catcaaacaa
    15181 gcgagtcatg atatcgaatt tttcgtattc ttttgcgcgg acatagtatt gatcgatcaa
    15241 gtcagctgtc atttctttcg ctttgatctt cacatgatgt ggatttttca tgaatttaac
    15301 gccaatattc ttgatagctg gcggcatcgt tgctgagaaa agtaatgttt gtctttgatc
    15361 aggaacttgt gaaatgattt tttcgatatc ttccaagaag cccatattca acatttcatc
    15421 tgcttcatcc aaaactaatg tttgaacggt tccaagtttc aatgtgtggc ggttaatgtg
    15481 gtcaagcata cgtcctggtg tacccacaac gatatgtgga cgatctttca agccacggat
    15541 ctgacggcca atatctgctc cgccgtaaac ggcttgtaca cgtacttttt tgtcgcgccc
    15601 taaacgatat aattcttctt gtgtttggat agctaattca cgtgttggtg cgataactaa
    15661 accttgtaat tcgtgacgat ctggatcgat tttttctaac attggtaatc caaatgcagc
    15721 tgttttccct gtacctgtct gtgcttgtcc aataacgtct tttccagcta atgctagtgg
    15781 aatcgtttct gcttggatag gcgttgcttc ttcaaaacca gcgcgttcga ctgatttcaa
    15841 caattctggt gataattcta gttctttaaa tttcaaatga atcctcctat atggttgtta
    15901 actgaggatg tagctttttt gctaccccgt cgatttgttc ggtcaaagtg tattgtttct
    15961 ttttgacagt ggccacgcac gtttttatcc attcttagcc cctgtggcac caccgaaaaa
    16021 tcactttgcg aagtttaggc attagaaaag ccaaacgggt cgcgttcagc tttatcatta
    16081 ttatgacatc tggcttcaac aagttgtttc tatggcaaaa ccagtccaat ttctcttcat
    16141 ctttcggcaa taggttattc taacatagtt tttcgttttc tgcaagttta cagattttta
    16201 tttcatttgc tgaagttgtt ctaccacttc aaataagccc atgctgttgc tgccttttag
    16261 cataatacta tctgttgctg caagattttg tttgatagca tcaatcaatt tattcttttc
    16321 tttttcaaaa tagaacacag gtagttgggg gtatttttgg ttcaattctt cttttagtgc
    16381 atgcatttgt tccccataaa ggaaaatcat ggcgaatttc tcaggatcga tatgttcact
    16441 catttgcgca tgcatattta aagactcttt ccctaattcc agcatatctg ctaacacagc
    16501 gattctgcgt ccttttgttg gcagattttt aaaagtatct aataccagtc ccatggctgt
    16561 tggatttgca ttgtagacat cgctcaaaat agctgcacca tttcctgccg ttagccattc
    16621 ggttctgttt tgagtgatag aaacatgggc gagcccttgg cgtatctcag gtatggacag
    16681 tccaaagaag cgcccgatcg tatacgcaat caaagcattc gttacattat aacttccagg
    16741 cagcgggatc gtaaatgttt ctccttctac tacaaaatcg gtttgtgctt ttccttttgc
    16801 tgtcacttcc gcatgaacat cgccatttcc aataccgaat gttgtgactg tttgtactaa
    16861 tgttgccgtt aaaggtgtca gcaacggttc atctgcgggc acaacgagta atccgtctga
    16921 tacaagtccg tcagtgattt ccattttggc tttagcgatt ccttctcgcg acccaagatt
    16981 ttctatgtgt gcttcaccga tcattgtgat tgctgcagct tttggttgag ccataagtga
    17041 aagttccgtg atttcattgg cgtgatccat gcccatttcc aaaacgatct tttctgtatc
    17101 ttggggcatg tgcaaaatcg tgtaaggaag accaatatta ttgttgtaat ttccttgcgt
    17161 cttatatgtt ttgtattttt cagacaagac agacgcggtt agatctttcg tggtggtttt
    17221 accattgctt cctgtaattg caacgacttc tgcgcctact ttttccaagt aataggttgc
    17281 caattgctgc atggctttca aaggatctgc tacaggaata actggaaaat tttttggagc
    17341 ttgttcaaca ggcaagctcc aaaatgaagc agatgctccg tttgtgatcg cttgctggat
    17401 aaattcatgt ccatctcgcg taccagcaag aggaacgaat aaacttcctt cggttatctt
    17461 ccggctgtca aattcgacat tggtaatctt tgtcagtgca gagcattcgc tgcccacggc
    17521 ttgtgcaatt tcttgtattg ttagattcat tgagatctct cctaaaaaag gttgtgaaaa
    17581 aagcgtttgg cctaaacggc gggttcgcat gactctcact tccaagtaaa tttctctatt
    17641 cgtatttaga agctagaatg aacgcggtta cgcaatcact ccagcctctt ctttatttct
    17701 ctttattcat ttttttcaaa aaaagattga cgctgatggt atcgattcat tcctaactgg
    17761 atcagttctt caatcaaatc accgtatttc aagcccatat tttcccataa gagtgggtac
    17821 atactgaact ccgtaaatcc tggcatagag tttaattcat tcaggaataa ttcattttta
    17881 tttgtcaaaa agaaatcgca ccggctcaat ccgcttccac ctaacatcgt gtaagctaac
    17941 ttcgcgtact cttgcgcttt ttgataaact tcttctggca cttcggctgg aatctgcatt
    18001 tcgattttat tattgatata ttttgcttca taatcataga atgctacgtc ttttacgact
    18061 tcaccaggca aagtcgtccg aacgtcttca tttcctaata cagcaacttc gatttcgcgc
    18121 gcttcaattc cttgttcaac gattgctcga gaatcatact gataggctgt tgctaaagca
    18181 ttttgcagct cttctcggtt ttctgctttt gtaatgccga cactagaacc catattcgcc
    18241 ggtttgacaa acatcggata aagcaaagaa ccttcacatt gatcaaatac ttttttagga
    18301 ttttctttcc attgattctt aagtactggt acataaggaa cttgcggcac accagcagct
    18361 tgtaaaatat acttggtcat gattttatcc atggcacatg cactggtcaa tacgcctgcg
    18421 ccgacataag gcatattcaa tgtctctaag aagccttgga tcgttccatc ttccccgttt
    18481 ggcccatgta aaactggaaa aacgatggct ccttcttctt tgatttcgcc cggattgatc
    18541 acttttcctg taaagccttc ctctgtctgt ccacttgggt cccatgaaag atgcaagaca
    18601 tctttgctgg caggtttttc tgttagtaat ggacctttga cccattgtcc ttcttttgta
    18661 ataaatacga gttgaacttg gtaataatta taataaatgg catttaaaac tgaaaatgcg
    18721 gaaagaatgg acacttcatg ctctgcgctg cgtccgccat atagtaaagt aatcttcaaa
    18781 agattgtcct cctgtattct aaatcgttca gtgatttact ctcatatttt agcacaaaac
    18841 aaaaataaac gaataactta tttataaaaa aacgagccag cttctaaaag aacgagcgtc
    18901 atttattttt tgtcagctag attatttgtc ccgtttttta taaaaagtta tgataaagaa
    18961 aaggagggat gatgatggcg caaacaaatc cacgcagccg cttggcagaa atcattcgag
    19021 tgttcatcaa ttacaatgta gtgccaaact ttgtacagca aaaaaatccc gaacaggtaa
    19081 aaaaagcctt tgaagaacta ggccccacct tcatcaagat aggacagatg ctttctgttc
    19141 gagaagattt gctttcttct gccttcactc aaacattcaa aacattacaa gatagtgtac
    19201 ctagcgacac attttcaacg gtcaaaaaga cgatcgaaac agaactttct ctttcattat
    19261 cagatatatt cgatgatttt tcaaaatcgc cttttgcctc tgcttctatg gggcaggctc
    19321 atcgtgccaa gctgaagaac ggtgacgcgg tagtcgttaa gatccaacac cctaacatcg
    19381 ccgaagagat ccgacttgat cttcaactat ttgaacgagc gatccctttg atcaaataca
    19441 ttcctgaaac tagcgtagtt gatctaaaag gggtactcca agaagtaaaa cgttccttga
    19501 tcaatgaaat ggacttctta aaagaaagtc aaaatggcga acaattctat caaaagaaca
    19561 atggctggaa agagatccgc agccccaaga tttatgacgc tttttgttcg aaaaaagtga
    19621 tcgtgatgga agaaatgtct ggtaaaaact tgaatcattt aatgaacgcc gaaaacaaaa
    19681 ctgaaacttt tatcactgga attcaaaaca agcagctgaa acaagaagtt gcaaagcttt
    19741 tagttgagaa ctttatgaaa caggtgtttg atgatggttt tttccatgct gatcctcatc
    19801 cagggaatct gctattccat gtactaacaa aagaagaaca gacacaagct agccgaaaaa
    19861 ctgaaacagt ccatgaaaaa gagttcggtt cctttgcttt tcgagcctcc acttctgcag
    19921 aagaccctgt tgcgccatat accatcaact acatcgattt tggtatgatg gggcatcttt
    19981 ctgcaggact taggcaaaaa ctcacacaag ccgttttagc gctgtatacg aaagatgctt
    20041 atcgaatcga aaaagcggtc cttcgacttt gtcagcaaga aggctcgttt gatgaaagtc
    20101 ggttccacca agaactgaca agttttcttg aacagtatta tgattctcct attgatgaaa
    20161 tcaacttgca agaagtattc acacatgtcg tgacgatttg tcatcaaaat aatctgcagt
    20221 tcgatcgtga tatcacgctt ttgctgaaag catttgggac attagaaggg gtgatccgcg
    20281 tcctcgatcc tgaagtttcc ctcatggaag tcgcttcgcc ttttgctcaa cattattttc
    20341 tcactcatct ggatgtagaa gatacattga aacaaagcgg attagactta ttggaaggga
    20401 tgaaggctgc gcctaagatc cctcaacagc tccaccatct attagaaatg tggacttcgg
    20461 gacaaggaaa agtcaatttg gaattgaaaa agcaagacaa attattgagc aggatcgaaa
    20521 gtatgatcaa tcggcttgtt ttcggtatga ttttagctgc attgatcgta gggtcctccc
    20581 tgcttgtcca agcagcacct gtagaaaacg cagaggtcgt ttccttatta gggatattta
    20641 cgtatgctat tgccgcattc gtcattattt ttttggcaat cgatgcattg atccaaatgt
    20701 ataagaagag gaaaaagtag aaaaaggttg tgacagaaag aatcagcttc aagaaataag
    20761 aaggggtttt acataaattg tttctcaaat ttttgtgaaa attcggctta tttttcgaag
    20821 aggctacttc tgaaacaccg agaataaaaa atgtgaaaaa gctgttctgc acccagtaat
    20881 aagaacaatc aaaaagggaa catggaacac atttatcctg tttccctgtt ccctttttga
    20941 tgtattcgag cataaataaa ataccttcgt tacctactat cttctgtact tggtaaacct
    21001 tagtcaattg ccttttttaa cgcttgacga aaagacatat gatctttctc cgtaaagggt
    21061 tttggaccct ttgtccttat gccagctttt cttaactttc cactatgata acgttgttct
    21121 agaagcgtgc cgatattcgc ttcgtcaaat tcttttccag agtgatggaa cactcgcaca
    21181 cccttcggca atacaagtga agctaaacca taatcttgcg tgatcaaaaa gtcattcttc
    21241 ttaaccatac cgacgatttt ataatccgca ctatcagctc cgcggtctac gtagacgatt
    21301 tggacatgat tagcgtattc tttggtcgta taatggtcca cactggtcac gataaccacg
    21361 tcaagaccat aggattctcc taattttatg acatcttctt ttactggaga accatctcca
    21421 tcaatgaata gcctcattct ttttcgcctt cttccataaa tgataaacag ttactaatcc
    21481 gctcagtaaa agaccaacat tgatccattt tgccaagata agcagttgta cactttctat
    21541 cggcactgat tcatggttca gcgtgatcaa taatagatgg attggctctc ccatttcttt
    21601 tgctaaaaca aacaaaagcg tcatcaataa aaactggtgg atcacactcc ctttattttg
    21661 agtagtatac ttgacaacga tccggcgatc cattggaata gctgtatcag tttgataata
    21721 ttccttattt agccagctgc ctgttactac gtgccagaaa ctaagcagaa agacacctat
    21781 cgcaaaacca tttggaatca agaggaccaa taaagaagaa ctcagtccaa gcaattgcat
    21841 agccaatgga gaccatgtta aacgtttcaa aatccatggt ccgactattt ttgctgcaat
    21901 caagcctgct gcataaggca aatacataaa aatcgaaagt ttttctaatc cgtacagtat
    21961 gccaacataa aaactgctaa ataaaaaaag gaaattccct agcattccat ttagaaaagt
    22021 aaacagattt agccagcttg gcaacttcca ttccttcttc tggtgtccta aaacaaacac
    22081 gaacaagatg aacagcagca agaaaccata aatagcaaga tcaaaaagcc tttcatcgaa
    22141 taacaatcgg gcatttctca aaagaaacaa taagccaaag aatatcaaaa ataaaacaag
    22201 ctctcgcgta gctaccagat ttcttttgat gtctttgaaa tccagttcgt aacgcggata
    22261 atgactaacc gtatggtagg ccatgacgta aaaaagtgta taaatagtaa agcttgctgc
    22321 aatctgagtc ggtgcaggca actcaatcgc ttgatacagg agaaatagcc agatagctgc
    22381 aaataagtac tttttcccat ccatattgat aaaaccttgc gtcttttcgt gaaaattgac
    22441 cgtggtatta gcaggtacaa gccatgctgc actcagccct agcaaaacac ttgaaaaata
    22501 aaataaagga aaataaaata cgcctaatat tccaagcaat gaaccagcac caccaatcag
    22561 cagagcgatc atcagcaacg tgtaactatc tagaccaaat cgtagactgt tgactaaaaa
    22621 tagtccagtc atccgaaagg cataaaacag cgtaaatggc aaaatcgtca gccaattatg
    22681 cgagtctgtt agtcccaaaa ataaaagata aggaataaaa ataaccgtgt tacttaagat
    22741 aaagggcgtt gtttgtgtaa aattacgccc aaatcgtttg agtttttcga acatgacaat
    22801 ggctccttaa acagtcttat aactaatctg ctcttcgatt ttagcattaa aggggaaata
    22861 aaccaatttt acagaatata ttcttgtaaa aaaaaataca gaaagaagca taagcttctt
    22921 tctgcatttt tacggtactt gattactcaa gcagacaagc ccttctccac aaaagtcttg
    22981 cccgacaccc ctgcatccgg caggtgataa agatagaaat caattatcct gtgcctccaa
    23041 aatcaattag gagctctgta aaccagagtc cttctcgacc cgtcgcataa atttacttta
    23101 acacagttcc tatgtttatg cgagagcttt tttcatttta taatcgacca tttgaaatcc
    23161 ttgaccgata tctgaaataa gttcttctgt aatctcaaat ccttcatgct tataaacctc
    23221 gattgcttga tgattcccct gattcactcg caaaaagatc tctctttcct ttgtttgcgc
    23281 agcaagttct tcataccagc gaaaaactga agaagtcaat ccttgaccac gtactttatt
    23341 tagcaaatat aatttactta aataaatttt tccatttatc tcttcataag cagtgtaacc
    23401 gacagtcttt tcttcgcttt ttaataaaaa gtaggacaca ccttctgtca gttctttttg
    23461 aatctgtttt tttgactgat aagttttcag catgtaatcc acttgttttt gaccaatgat
    23521 cggcacaaaa gcttccggcc atacttcttg tatgactgcc atcagctcat ccagttcatt
    23581 ttctgttact tttatttttt ccatacaccc acgtcctttt ttacattata aatgaccttg
    23641 cgcttgatgg aataaaaaga gcatgatcat gctatacaca cccaccgacc atggtttcaa
    23701 gaaaatcaca atctgcataa attccctaaa agataatttc gtcaaaccag ctactagaca
    23761 gatcaagtcg tctggcgcaa agggaagcag caaggtaaca actagtactt ttttaatatc
    23821 tttcgttttt cttgtcagca attcatcaaa tttctgatac ttttttggcg ataaaataag
    23881 ctggacaaag gctacgccat agtaacggac aagcaaaaat ccgattgctt ccccaatcac
    23941 taggccaata caactatata aaagcccaaa tccattgcca aacatcagca tgcccgctac
    24001 tgaggagatc cctcccggca aaataggaat gatcacttgg atcacttgca acagaacaaa
    24061 tatcatcact gcatacttgc caaattgctg gataaacgct tgcaaagacg tgctcgatcg
    24121 aaaaatccca tgatgataag cataaagaat caacacaaag aaaaaaaaca gaccaataat
    24181 gggcatgatc tgaagacatt tttgtaaaac tgatcctttt ttagacatct atattcccca
    24241 catctttttt catttattaa aactgcctcc tt
//
LOCUS       DACDAF010000038        23954 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.038, whole genome shotgun sequence.
ACCESSION   DACDAF010000038 DACDAF010000000
VERSION     DACDAF010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.038"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            36..266
                     /locus_tag="IVZ69_001411"
     CDS             36..266
                     /locus_tag="IVZ69_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183502.1"
                     /translation="MGFRTKRSLSSKKNWVYSQTIFYGGIVLISLLSSTLYSLNIIDV
                     STSNSISIIGIIIAAIITQLFLVFGEKKRSKK"
     gene            complement(357..722)
                     /locus_tag="IVZ69_001412"
     CDS             complement(357..722)
                     /locus_tag="IVZ69_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183503.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            930..1412
                     /locus_tag="IVZ69_001413"
     CDS             930..1412
                     /locus_tag="IVZ69_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183504.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     LVVSRNFPALTVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDSAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1609..2499
                     /gene="pstS"
                     /locus_tag="IVZ69_001414"
     CDS             1609..2499
                     /gene="pstS"
                     /locus_tag="IVZ69_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HAP8183505.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            2825..5299
                     /locus_tag="IVZ69_001415"
     CDS             2825..5299
                     /locus_tag="IVZ69_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP8183506.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGHQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKVIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLLKRRNNTVAMTGDGVNDI
                     LAMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLV
                     KNIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNV
                     MEKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKF
                     RSQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLF
                     ERKNEKEQKPFSRVVKKFLSIFKREN"
     gene            complement(5402..7138)
                     /locus_tag="IVZ69_001416"
     CDS             complement(5402..7138)
                     /locus_tag="IVZ69_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HAP8183507.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNGDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRAYTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLHGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(7135..7839)
                     /locus_tag="IVZ69_001417"
     CDS             complement(7135..7839)
                     /locus_tag="IVZ69_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8183508.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            7970..8473
                     /locus_tag="IVZ69_001418"
     CDS             7970..8473
                     /locus_tag="IVZ69_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HAP8183509.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            8433..8771
                     /locus_tag="IVZ69_001419"
     CDS             8433..8771
                     /locus_tag="IVZ69_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HAP8183510.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            8792..10210
                     /gene="ffh"
                     /locus_tag="IVZ69_001420"
     CDS             8792..10210
                     /gene="ffh"
                     /locus_tag="IVZ69_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HAP8183511.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            10322..10900
                     /locus_tag="IVZ69_001421"
     CDS             10322..10900
                     /locus_tag="IVZ69_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HAP8183512.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            10904..11425
                     /locus_tag="IVZ69_001422"
     CDS             10904..11425
                     /locus_tag="IVZ69_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP8183513.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(11504..12058)
                     /locus_tag="IVZ69_001423"
     CDS             complement(11504..12058)
                     /locus_tag="IVZ69_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP8183514.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            12311..12586
                     /gene="rpsP"
                     /locus_tag="IVZ69_001424"
     CDS             12311..12586
                     /gene="rpsP"
                     /locus_tag="IVZ69_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HAP8183515.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            12598..12849
                     /locus_tag="IVZ69_001425"
     CDS             12598..12849
                     /locus_tag="IVZ69_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HAP8183516.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            12973..13764
                     /locus_tag="IVZ69_001426"
     CDS             12973..13764
                     /locus_tag="IVZ69_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183517.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTATTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            13934..14455
                     /gene="rimM"
                     /locus_tag="IVZ69_001427"
     CDS             13934..14455
                     /gene="rimM"
                     /locus_tag="IVZ69_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HAP8183518.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            14445..15206
                     /gene="trmD"
                     /locus_tag="IVZ69_001428"
     CDS             14445..15206
                     /gene="trmD"
                     /locus_tag="IVZ69_001428"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HAP8183519.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            15342..15689
                     /gene="rplS"
                     /locus_tag="IVZ69_001429"
     CDS             15342..15689
                     /gene="rplS"
                     /locus_tag="IVZ69_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HAP8183520.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            15999..16241
                     /locus_tag="IVZ69_001430"
     CDS             15999..16241
                     /locus_tag="IVZ69_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HAP8183521.1"
                     /translation="MNDGKVKQVPSSTKKKNILLKEVLKRFDHGVTYTETEVNSILLN
                     VFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(16329..16442)
                     /locus_tag="IVZ69_001431"
     CDS             complement(16329..16442)
                     /locus_tag="IVZ69_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAAX protease"
                     /protein_id="HAP8183522.1"
                     /translation="MYAPGTILLTIAYLTANRSLAFIIAIHILNNVLGFVL"
     gene            16592..16846
                     /locus_tag="IVZ69_001432"
     CDS             16592..16846
                     /locus_tag="IVZ69_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP8183523.1"
                     /translation="MLELSKQLPVSDPRHFDYEEIAIKILEELQKNYTTKRVNGSNGL
                     LLHAVYDKNSLKGVDECVIWGDYFYVEGITRLAKTWYCYW"
     gene            16875..18134
                     /locus_tag="IVZ69_001433"
     CDS             16875..18134
                     /locus_tag="IVZ69_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP8183524.1"
                     /translation="MKRWKKMMIGSIVLGMSLVFGACGNQEDSSEESANEITVSTWNY
                     ETTPEFKALFEAFEKKTGIKVKAVDIASDDYDTKLTTMLSSGDTTDVLTMKNLLSYSN
                     YALRDQLVDQTERIRELDTDAAEETYEMYDIDGKTYALPYRTDFWVLYYNKKMFDDAG
                     IEYPKNLTWDEYEDLAKKLSKNDGQVYGAYQHIWRSTIQAIAAAQNEANLVEPDYQYM
                     TDYYDRALRMQKEGAQMDFGTAKSTKVTYQSQFEEQKAAMMYMGTWYMAGILANKEAS
                     KTEVEWGITAIPQKKKGESVTTFGSPTAFAVNKNSKKQKAAQEFIEFAASEEGAKVLA
                     GVGVVPSYRTDEIDQLYFNLAGMPTDEISKKAFSPDEIKLEFPIDTYGPAIDKILQEE
                     YDLVLVGDETPEKGTVNMEKRVAAEKE"
     gene            18187..19083
                     /locus_tag="IVZ69_001434"
     CDS             18187..19083
                     /locus_tag="IVZ69_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8183525.1"
                     /translation="MENSINKKATNHLRRKRTWIAYSFIAPNFIGFFVFTLIPILFSL
                     VLAFMKWDSFSTPEFAGLDNFRKMANDETFWISLKNTFLYTAAVVPGTLVCSLGLALL
                     LNQKIRGMKLFRTIFFFPYVTSLVAIAVVWNMLFHPTVGPINIFLRRFIEHPPGWTSS
                     SNWALWAIVIVSIWRGMGYYMILYLAGLQSIQKELYEASSLDGANRWKQFLNVTLPSL
                     RPTTFFVTIMLVINCFKVFDLVQVMTDGGPGRATNVLVYQIYNEAFKKFDFGYASAIS
                     LVLFVIVLGVTVVQFSWNKRRT"
     gene            19094..19963
                     /locus_tag="IVZ69_001435"
     CDS             19094..19963
                     /locus_tag="IVZ69_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8183526.1"
                     /translation="MEESVRNERKKAKIRSKNMPFIQWLGMILLIVLALLTIIPFLWM
                     VSASFKANNEVLTIPIQWIPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFT
                     SSFAVYGFSELNFKGRDILFLAYIGTIAVPWQSYMIPQFIMMRKVGLTDTLWSLVLLQ
                     AFNAFGVFLLKQYYSSIPDSLCESARIDGLSEWEIYRKIILPLTKPAIASLTIITFVN
                     TWNDYMGPFIYLSSTENKTIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQK
                     YFVEGIASSGMKE"
     gene            19973..20648
                     /locus_tag="IVZ69_001436"
                     /pseudo
     CDS             19973..20648
                     /locus_tag="IVZ69_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
     gene            20854..22518
                     /gene="alsS"
                     /locus_tag="IVZ69_001437"
     CDS             20854..22518
                     /gene="alsS"
                     /locus_tag="IVZ69_001437"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HAP8183527.1"
                     /translation="MAEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVEKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAKLTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            22531..23241
                     /gene="budA"
                     /locus_tag="IVZ69_001438"
     CDS             22531..23241
                     /gene="budA"
                     /locus_tag="IVZ69_001438"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HAP8183528.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            23371..23868
                     /locus_tag="IVZ69_001439"
     CDS             23371..23868
                     /locus_tag="IVZ69_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HAP8183529.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
BASE COUNT         7926 a         4105 c         4973 g         6950 t
ORIGIN      
        1 atatatggat ttttgatagg agtagaaatg caagtatagg ttttagaact aaacgaagtc
       61 tgtcttctaa aaaaaattgg gtatactcac aaactatttt ttatggagga attgttttaa
      121 ttagtttact ttcttcaaca ctttattctt tgaatattat agatgtttcc acctcaaatt
      181 caatatctat tattggaatc attattgctg caattattac acaactgttt ttagtgtttg
      241 gagagaagaa aagaagtaaa aaatagaaaa actagtgata gttttggtga tataagaaaa
      301 acatatatgt ataaaaagaa gaaagtagct tctctttgta catatatggt ttgtttttat
      361 ggatgccgag cttttttata agataaggct accgcccata acgacccaag gatttgtgga
      421 actaagtaaa tacctgcaag aagcaagatc agctgggtcg gttttaaagg atgatagaag
      481 taacgccatt cagtaaaatt ggcgcaaaat aaataggaag tgacagtaga tataatattg
      541 gcaatgaata aagatataat acgcctgttc ctttgaaaat aatatccagc aaaaagagat
      601 aaaaatatca atgtgatgaa cccgcttacg gaatgataac gaaaatcaag cagtaaggcg
      661 aaatgcacat aaggaacaaa agataaaagc aacggaaggt ttttccagca agtttttatc
      721 atctttcatc accacctaac aagtgttatt attttgttag ttttattgta aattgaatcc
      781 tgcaataatc aattactttt tcattatttc tagattaaat gaataaactc tcatgccatt
      841 atctctaaaa aaaaagtttt tccccctaat ttttttagat agaaaattgt atagtatgat
      901 gagagaaaaa gtagtttggg ggaacgttaa tgagaagaaa agcagtaatc gatcggcttt
      961 atttattttt ttggtttttt cctatcgttt tgctaccttt tacatgggta aatgctgttg
     1021 tacaaggtgc ggagatatta ggcctgatcc aaggaagcgg attagtggtt tctaggaatt
     1081 ttccagcttt gactgttttc tatttagtga taagtgtagg tctcttatta ccaaaatctc
     1141 tgatcaatca ctacaattgg cagctgcttt acttttcttg cttattagta tttacatcta
     1201 tgttttcttt gctgcctcgc ttgattatcg gccctaatgg tttgagcgag agtggattga
     1261 aggattcagc ttattcctcc atgtatttct tgacgatcaa accatggttc tatttagtaa
     1321 ttgcctcatt tattcttgca acattttttt acttctggac agaaatcagg ataaaaagtg
     1381 aacgatctgt atctataaaa aataactatt gatggtggat catcagtaaa aaagcatatg
     1441 agctgcgtaa aatgcatgtt tctcatatgc tttttttatt attatgtaaa gaatgcgaaa
     1501 aacgtttaca tgatttttac ataacttaac tatattttta cagcaaccat acgagggatt
     1561 tacagtcgac tgataaactt tagttgtaaa taagaaagga gcaataaaat gaaaaaagta
     1621 ttgtttactc taggtatgat gggaattctt ttagccggat gcggctcagg atcaggaaat
     1681 acagatggct ctgccacaca aaataattca agtgactcaa atgaacaagt aaaaatcgtt
     1741 gcggtaggtt cgacagcatt acagccgtta gtcgatgcag cacaagaaag ctttgtacaa
     1801 gaaaatccaa attatcaaat ctctgtacaa ggaggaggaa gcggaactgg tttgagccaa
     1861 gtcgaagctg gagcagttac tatcggaaac tctgatgtat ttgcagaaga aagagacgga
     1921 gttgatgctt caaaattagt ggatcataaa gtagcagtgg tcgggatggc accaatcgtc
     1981 aataaagata cagatgtcaa agatatcacc aaacaggaat tgattgatat ctttacagga
     2041 aaaatcacta actggaagga agttggcggg aaagatcaaa aaatcaacgt cgtgaaccgt
     2101 gcaaacggca gcggtacccg cgcgacattc gaaaaatggg gactggatgg tgctacccct
     2161 gtgcagtccc aagaacaaga ttcatcagga acagttcggc agctggtaag tcaaacacca
     2221 ggagcaatca gctatttagc tttctcatat ctcgatgatt ccacacaagc actaagtatc
     2281 gacggtgtag aaccaaaaga agagaatgta gcagataaca gctggggaat ctggtcatat
     2341 gaacatatgt acacgaacgg aaaaccttcc cctgaagtcc aaaaattctt agactacatg
     2401 atgacagaag aaatccaaga aggacctgtc aaagaattgg gctatttacc aatcacaatg
     2461 atggaagtag aacgtgatca cgaaggaaat atcaaataac tagcagataa acatgccacg
     2521 gtagtcgtta ctattaagga aaaatcaact atgtttcccc acatatacat ttttccttta
     2581 attgtgaaaa atagttcctc atattttgcc gttttttgag ctaataccga gggtcagctg
     2641 attgaacacc gtttattcga aaaaaagagc tacgacatag aactgtcgta gctttttttt
     2701 tgctatatga caggaatgaa aggtgtttgc aagcttaatg tgaggaacac tttccatatc
     2761 tgttctatac tggataggag aagtttggaa atatccagaa aacgaaatca atcgaggtag
     2821 ccacatgaag aataaatgga taaatcgaag taaaaaaaag aaagtaacac aaagatcatc
     2881 agataaagtc atccgtcttt ttccatcgta taaagaagga ttaacggcag atcaagtcaa
     2941 ggaacgaata gaaaaaggtg cagcaaataa ttcagtcgat cccacattca aaacaaatca
     3001 gcaaatcgta ttggaaaaca tatttacgta tttcaatttg atctttctta tcttagccat
     3061 tttgctttgt ttagtagaat cctataagaa cttgactttt ttaccagtta tcatagccaa
     3121 tacaggaatc gccatttttc aggaaattcg atccaaaaag atcttggacg aactaaatgt
     3181 tttaaataca gcaaaagtca atgtcatacg agacgggata gaacaaacaa tagatataga
     3241 agaccttgta atagatgaca ttgttatttt agagactgga catcaaattc cagcagatgc
     3301 agaggtcgtg gaagggaaac tgcaagttaa tgaggcttta ttgacaggcg aagcagatga
     3361 aataaccaaa gaaataggcg atccattaat gtccggcagt ttcattgttt ccggaaaagc
     3421 ttacgcccga ttagacaaag ttggagcaga ttcgtatatt tcccagctga cagtcaaagc
     3481 caagacaatg ggagaaggag aacagtcgga gatgattgct tctcttaatc aattgatcaa
     3541 atggattggg atcatcatta ttcctatcgg tatcctgctt ttttctcaaa gttacttttt
     3601 taatggaaac acgatcaaag aaagtgtcgt tgcaatggaa gcagcattga tcggtatgat
     3661 acctgaagga ctgtacttgc tgacgacgat tgcattagca ttaagtgcga ctaaactagc
     3721 aaagcaaaga gttcttttac acaatatgaa aagcattgag acattggcaa gggtaaatgt
     3781 cctttgtgta gataaaacag gaacgatcac agaaaataaa atgtctgttc aaaaagtgat
     3841 cgtctctaaa aaacaagaaa taatcagtca gtcagatcaa ttggaagcat gcattgctga
     3901 ctatgcaaaa gcgatggcag gagacaatgc aacaatggaa gctgttaaag catattttac
     3961 aaaaaccact gatcaatcct atcaccatgt tattcctttt tcttctgtcc aaaaattcag
     4021 cagtgtagcg ttggcagaca aggtgtatgt tttaggagcg cccgaaatgg ttttgcgcga
     4081 tcaattgccg gaatatgcgg aagagtttgt ttctttcgct gaaaaaggct atcgcgtgtt
     4141 ggtctttggt gtgtacgatg ggattcttga agaaccagta ttgacagaag cagtcacacc
     4201 attaggctat attctgattg ctaatcctat cagaaaagaa gcaagagcca catttgatta
     4261 cttcaaaaaa cagcaagtag ccatcaaagt gatttctgga gataatccgc tcaccgtatc
     4321 caatgtagct gtccaagcag ggatttcaca tgctgatcag tacgttgatg catctaaatt
     4381 atcagaagaa gaatatgaag cagctgtcga aaaatataca gtttttggac gcgtcaagcc
     4441 agaacaaaag aaaatcttcg ttcaattgct aaagcgtcgt aacaatacag tagctatgac
     4501 aggtgatggc gtgaatgata ttctagccat gaaagaagca gactgcagta tagcgatggc
     4561 ttccggaaat gaagccgcca tgcaggcctc acaagtggtc ttacttgatt ctgacttttc
     4621 acgcatgcca gaagttgttg cagaaggacg gcgcgttgtg aacaatattg agcgatcagc
     4681 cagcttgttt ttagtgaaga atattttctc ctttttgctc tcactgtttt cagtgatctt
     4741 tgctctgacc tatcctttag aaccatcaca aatcacattg attagtttgt ttactatcgg
     4801 acttccatct ttcttgcttg ctctagaaga aaacaaaaag cgaatcagag ggaaattcat
     4861 catgaatgtg atggaaaaag ctgtgccagg tggactaaca gatatgatcg tagtcggtgc
     4921 gttggtgatc tgcggggtga ctttgaatct aaataaaaca gatgtttcta cagcatctac
     4981 catgcttttg attgcagtag ggttcctcgt tctctataaa atctgttcac cgctgaataa
     5041 attcagaagt cagatcattc ttttctgtgc tagcggtaac tttttttcgg tcatcttttt
     5101 gcataagctg ttttcaatca ccggtatctc agctgtatca cttttgctgt tgagcattct
     5161 atttttctcg gcagattcga tttttaggca tttgaccaca ttggtagaat atttgtttga
     5221 acgtaaaaat gaaaaagagc aaaagccgtt tagtcgcgta gttaaaaaat ttctatcgat
     5281 atttaaacga gaaaattgac gaaaagtatc tcaaaaaaga gtaaaaaaga acaaccactc
     5341 gtgtatcttt cgaagcagga tgagtcatcc aactttaaaa cgcacgagca gttgctcttt
     5401 tttacatttt cggaatggta acggtgaaag tcgaacctgt tccaagatga ctgtctacag
     5461 taatcgtacc atgaaggagt tgcacgtagt cttttacaat cgctaaccct aatccggtcc
     5521 cgcctgaatg ccggcttcgc gccttgtcta cgcggtaaaa acgctcaaag atccgttcct
     5581 gatcctcaat gtcgatacct ataccaaagt cttggacaga aaacgataga tcatctgttg
     5641 cctgatagcg gataataatc tcgctgtcgc tttttgaata ttggacagca ttttcaatca
     5701 gatttttgat aattggataa aggatatctg ttttagtagt aaatggttcg ttctttccaa
     5761 tcaatcgaat cgtcaaccgt ttcttttcga tgattggctg ataattttga acgatttgct
     5821 ggaaataagg ttctgtataa attgtctgga tctcgtaaga attctcgcca tcttttgaca
     5881 gctggatgat ttcccgaatc agtttatcta accggatcgc atctttttgc atgatctcaa
     5941 gaaaagaagt cagagtttgc gggtcatctt ttgcaccatc cagtaaagtc tcggtaaaac
     6001 caatcagtga agtcacagga gtttttaatt cgtgagagac gttgccaacg aaatcctttt
     6061 gtagcttttc taaacgtcgc actttcgtta agtcatacgc cacccctaga atctgtccgg
     6121 taccttctga attagtaaag tagcgcaaac tcaagtctaa tgtctgccga ccttctgtaa
     6181 gggtgatctc ctgatggatc agcggatgct caggagtcac ttgatgaatc agctgaatga
     6241 gttttggctc ttgaatgact tctgtgtacc gctgttcagg ttgatagctt accacgttta
     6301 aatgtagctg catctttgga ttaagcagta gtaaacgaga atcagcatca tcaatcagga
     6361 atacgccaat catcagttcg ttcagtaacg tatataattg ctcttctgtg gtagtatacg
     6421 cccgatacat cttactcatt tgttcgctca acgcattgat cgtctgatac aattcttccc
     6481 attgatcggg tgtttgcatg attacttccg cctgattagg attttgcacc atttttttta
     6541 gtacgggcag cacggttttc aatggctggt ttttttgata gatcagataa tagatcattc
     6601 ctgcaagaac aaggaagaaa gacagaaaga agaaaaagac ccaacggcga aaactctcag
     6661 ttctcggtaa aaaaccgctt gtcggttctg cgatacgtaa aatggcttct aactggccac
     6721 tttttttgac tggtaatgcg acatataaaa gatccccatt caaagtagta cttttgcgca
     6781 aagcgctacc taggttccca ccattcaata cggctttgat ttcgggacgg gagtttcgct
     6841 gttcattcaa tgtttcattg tttgtgtcaa ataagatctt tccagtagca tccattaaag
     6901 taatccgttc gttcgactga tggacgaatt cttccaaagc agttttgttt tgcgctgctt
     6961 ggaggttttc gacatctaat tgccggatca gcagttgtgc tttttttgtc aggtagcttt
     7021 cttgctgttc cacgatctgc tgttgaaaat aatgggaaat caattgccag ccaccaaaaa
     7081 acaaactaac taaaagaata agaaagaaga gacgttcata aatttttttc catttcatcg
     7141 tttgggttcc tgaaacttat agccaaatcc tctaatagtc accaagtact ttgggtgttt
     7201 tggatctcgc tcgatttttt ctcgcaaatg actaacgtgt acatctacga ttcggctttg
     7261 tcctgcgaag tcaaaattcc aaatgcggtc tagcaatgtg tctcggtcga tcacacggtc
     7321 ttttcgtttc atgaaataaa caagtaattc aaattctttc ggtgttagtt caatcagatg
     7381 gtcgtctacg gtcacttgat aattggtcaa atcagcagtg atttgtccaa tcgatagata
     7441 ttcaggctca gcttcatctt ttgattgctt acgaggttca attcgtctga atattgcttt
     7501 catacgggct aatacttcgc gaggactaaa tggtttggtc aaatagtcgt cagcacctat
     7561 ttctaggcca atgatccgat ccacttggtc atctttagcc gtcagcatca aaatcggtgt
     7621 ttcatttttt tcttgacgca gccgctgagt gatctccatg ccatccatcg ttggaagcat
     7681 cacatctaaa atgatgaaat caaatgattg ttctaatgct aattctaatc cttcgcctcc
     7741 atctgtggca ctggttacct tgtagccttc tttttccaaa ttgaacgtca agagcgttac
     7801 aatagaaggt tcatcatcaa caactagtat ttttttcatt caaatctcct ttaaataggt
     7861 ttcattctgt ttatatttta gcatagaatc agtacaaagg gctattttac aaaagaaata
     7921 aatggtataa taggaaggca ctttgctgaa tagaaaggaa gagcagtcaa tgattggaat
     7981 cagtgcatgt ttaggcggtc tggcctgtcg ctatgatgga cagaaaaaag aagtaccaga
     8041 attgatggaa ctagttgaaa ctggagaagc tgtcatggtc tgtccagaag tgatcggcgg
     8101 attaccaatt cctagagatc ccgctgaaat cattggtgga aatggattcg atgtgtggaa
     8161 agatcaagca aaagtatgga cgacaagcgg cgaagatgta acggaagcgt acaaaaatgg
     8221 cgcgatcaaa gcctatcaaa aattgcagga aaaacacatt gatctagtca tcatgaagga
     8281 aaaaagccct tcatgcggaa cccattcgat ttatgacggg agtttttccg gaataaaaaa
     8341 aaatggtgcc ggagtggcta ctgcttattt tattcagcaa aaaatgactg tgctctctga
     8401 tgaagaatgg ctgaaaacta gaggtgagca gaatggaaat cgaaaagacc aatcgaatga
     8461 acgcgctctt tgaattttat tcgaccttat tgacagaaaa acaaatgaac tacatggaat
     8521 tatattatgc agatgatttt tcattaggtg agatcgcgga agaatacgaa gtaagccgac
     8581 aagcagtata tgacaatatc aagcggacaa gcaagatctt ggaggattat gaaaaaaaac
     8641 ttcatctttt ttctaattat attgttcgag aacaggtatt ggaaaatatg actgcatata
     8701 ttacagataa gtacccggaa gataaaaaac tacttgaata tgtacagcaa attcaagcaa
     8761 tcgaagaata aataaaagga atgaagaaaa tatggcattt gaaagcttaa ctgaacgtct
     8821 ccagcaggcg atgggaaaaa taagaaaaaa aggaaaagta tcagaagctg acgtaaaaga
     8881 aatgatgcgg gaaatccgcc ttgccttact agaagccgat gttaacttgc aagtagtcaa
     8941 agattttact aagcgcgtac gcgaacgtgc ggtaggggca gaagtgctgg aaagtttatc
     9001 acctgcacaa caaatcgtaa aaatcgttga tgaagaattg acgatcacac ttggttctga
     9061 aacagcagag ttaaataaat caccaaaaat accaactgtt atcatgatgg ctggtcttca
     9121 aggggcaggt aaaacgacct ttactggtaa attagccaat tatttaaaga aaaatgaaaa
     9181 tgctcgtccg ctcctaatcg caggggacgt atatcgacca gctgcgatcg accaattgaa
     9241 agtattaggt caacagctag acgttcctgt atttgatatg ggaactgaag tcagcccggt
     9301 agagatcgtc cgtcaaggga tggagttagc aaaagaaaag aaaaacgact atgtattgat
     9361 cgatacggca ggacgtctgc atatcgatga aacattgatg gatgagttga aacaaatcaa
     9421 agaattgacg caaccaaatg agattttgct tgttgtcgat gccatgactg gtcaagatgc
     9481 cgtcaacgta gctgatagct tcaaccagca attaggtatt acaggggtcg tcatcactaa
     9541 acttgatggg gatactcgag gcggggcagc actatcgatc cgctcagtga caggcgcacc
     9601 aatcaaattc atcggttctg gtgaaaaatt gactgactta gaagtattcc acccagatcg
     9661 tatggctagc cgtatccttg gtatggggga tatgctgaca ttgattgaaa aagcgcagca
     9721 agactatgac gagaaaaaag cggaagaact tgcacagaaa atgcgggaaa attcattcga
     9781 tttcaatgac tttattgaac agcttgatca agtgatgggt atgggcccac tggaagatct
     9841 aatcaaaatg atcccaggaa tgaatcaagt ccctggaatc gaaaacgtca aggtagatcc
     9901 aaaagatgtt gaacgcaaaa aagcgatggt ttattctatg acgccagcag aaagagcaaa
     9961 tcctgatctg ttgaacccaa gccgtcgtcg ccgaattgct gccggttctg gaaacagtgt
    10021 tgttgaagtg aatcgaatga tcaaacaatt caaggaatca agaaaaatga tgcagcaaat
    10081 gtccaaaggg gatatgaaca tcccaggtat ggaccaaatg tttggttcag gcgtcaaagg
    10141 aaaactaggc aaaatggcga tgaatcgaat gatcaagaaa aataagaaga aaaagaaaaa
    10201 acggaaataa gatgaaaaaa acagcttcgg tacagactga aaatgtctac tgccggagct
    10261 tttctatcag caatttttat tctttactaa tacaattact ctaaacgaag aggtggcaca
    10321 gatgagatgt ccgtggagtg aacaaacaga aagtatgcgg caatatcatg atactgtctg
    10381 gggtgttcct gaatatgatg accaaaagct gttccgaaaa ttgatgcttg atattaatca
    10441 agccggattg agctggcaga cgattttaaa taaaagtgaa gcattcgatg aagcatatga
    10501 tcgattcgat attaaaaaag tcgcaaatta tggagaaaca aaaatcagtg aactaatgga
    10561 aaacaaagga attattcgta accgaagaaa aatcgaagca gccgtccaaa acgccaaagc
    10621 agtcttgaaa attcaagaag aaatcggcag tttttcagag tatctttggt cgttttctaa
    10681 tggaaaaatc gttgattctt cttatcattc acaagaagaa gtcccaacaa caagtcctct
    10741 ttcagatgaa ttagcaaaag atctaaagaa aagaggattt aaatttatcg gaagcacaac
    10801 aatctatgct tttttagaag ctgtcgggat catcaatgat caccttgaca gttgtttccg
    10861 caaagaagag gtcgtacgta tcggcagaaa gggcgaataa agcatgcgaa aaatcatatt
    10921 ttatggtgct ataagtttag atggctattt ggcaacgaaa acggatgatc ttcaatggct
    10981 ttttgacact ccaacaggta agcaaaccac ttatgaagct ttttatgaaa caatcgatac
    11041 gaccatcatg ggcagaaaaa cttatcagga agcaaaaaaa tatttggaga ccgaagcaat
    11101 ttatccagag aaaaagaatt tcgttttttc cacccacgca caattacaat tgccagatgc
    11161 tgaggtcgta aacgaagatc ctgttgcttt tctaaaaaat ctacaaatga cagaaggaaa
    11221 agatatctgg gttgtgggtg gcggtcgatt gatcaaaccg ctattggaac atcaaatgat
    11281 tgatgaatgg tatatccaga ttacccctgt attattaggg gacgggattc ctttattcca
    11341 aaaaggaaca tatgaagcgc gttttgaaat gctagacacg acacgattcg gtgaatttat
    11401 cgaattgcat tatgtacgaa agtagaagta aataaaataa aaaaggcaac tatatgcaga
    11461 aatgtcctgt acatagttgc cttttttatt accgttatgc tttttactct gttaatttgt
    11521 tagaaaaatc tagatacgca tctaaaatcg tttggaagaa acttaatgtt ccttcaacga
    11581 tattaccatt ttcatcaatt agattcgcaa cgtttccgat atatgcttcc ggttgctgca
    11641 aggttggcac attcaaaaag acaagtgatt gtcgtagatg gtggtttgcg ccaaagccgc
    11701 cgatcccacc tggtgatgca gtaacgacta aacctggttt atgatcccaa acactgtgtc
    11761 cataaggtct tgagcctaca tctaaagcat ttttcaatac tgctggcaca gaacggttgt
    11821 attcaggagt aacgaaaacg acaccgtcta gtcccctcac ttcctcacga aaacgagtcc
    11881 attcagcagg agcctgttct ggagtttcga gatcctcatt gtaaaatggc agatcatcga
    11941 tttttacaaa tacactttcg tacccttcag gaagcaattt cgcaaaagct tctgctactt
    12001 ttttgttgta agaatctttt cttaaactac caataaaaaa tccaattttt tttgtcatac
    12061 gatttttcct ccttcaaact atctataaca atcttacaaa aaataagtaa ctggagcaaa
    12121 taaaaacact tactgacaaa agctacatag aagatagatt acttattttt aacaaaaaag
    12181 aagtctaaaa tcttctattt cctaaaaaaa atcgaattta atcaagctgt aaagaaaaaa
    12241 agctttacag ggtaaaaaaa aactgttaca ctacatcttg tgaataaaac aatggaggtg
    12301 gaaataaata atggcagtta aaatccgttt aaaacgtatg ggttctaaaa agagtccgtt
    12361 ttaccgtatc gtcgtagctg attcacgttc tcctcgtgat ggacgtttca tcgaaactgt
    12421 aggtacttac aatcctttga aagaccctgc agaagtagtt ttaaaagaag acttagttct
    12481 tgactggtta tcaaaaggtg cacaaccttc tgacactgta cgtaacatcc tttcaaaaga
    12541 aggcgttatg caaaaacacc acgaagctaa attctcaaag aaataaggtg accggatatg
    12601 aaagatttaa gcgacttagt cttaacaatc gttcgtccgc tagtcactta tcctgatcaa
    12661 gtcaagttag acgtcgtaga gtcgaaagac ttttacgagt acaatctaac agtggctcct
    12721 gaagatattg gccgtatcat tggaaaacaa gggcgtgttg ctaaagcaat ccgcacaatc
    12781 gtttacggtg ttcggatcaa tgcaccgaaa aaagtgcgtt tgaatatcat cgatgataag
    12841 gaaaagtaaa taaacgtgct gtactcgaat tttcgagtgc agcttttttg tttttttatt
    12901 aattgaagaa atgattattt ggcaaaacaa gcaagaaagc gtatccttat aggaggaggg
    12961 agtgaacagc caatgagaaa gaaaatgtta tttattccat ttgctctatt gttaagcgct
    13021 tgtagttcgg ttactcaaga atcagacaat acacatctat caagcagtat atctgaaact
    13081 gttaccagtc cagaaaaaag tagtaccaaa acggctacca ccactgaaca aacaatggct
    13141 acctcaaata atgagaaaaa gactgcttta gaccagttga aagaacaaca gccaaatgtt
    13201 cccatgcctc tagatgtacc agtctcttca ggctatctca atatcgcagc gacacataca
    13261 aagcaaggtt attctatttt atattacaga acagatcgtc ccctcgggtt gaatgctgac
    13321 gaattgaatc aagaaacgcc tattgcaacc tatctatatc aatatgggtt tgcttctagt
    13381 caagaaacaa tccaagtttt gcagcccttt gagatcgaca caaatggtca gcaagtggac
    13441 ttaggttctc gaatcacagg gtatcagcaa ggtgcagcag gttcaagttt tcttgaatgg
    13501 caagaaggaa actggcgtat tcgaatccgt gggaataata tagaaggcca agatccctta
    13561 ctattagcta aagaaatcgt agcttatttg gaagaaaaca gtctaccagc acctgaacaa
    13621 tttggtaaaa ttactgttga tatgggtgat acgacgaatc gagccgtaga agtaagctgg
    13681 caagaaccga aaaatgccta tacgatcact catcaagatc ctatgtctgc gttgaagatg
    13741 gcagtttcta tgaagaggtt gtgaaatcag cgcgctgatc tgagcccatc atttaactcc
    13801 aagtcacagg aagtaatcaa aaatagcacg ccgcattttt gcataatttt ggcttaatac
    13861 cttaaaagaa aactagaatt gcctcttcac acatgctaaa ataaaacaga caaaaaagaa
    13921 atggggatat aagttgactg aatacttgaa tgtaggaaaa atcgtaaaca cacaaggtat
    13981 caaaggcgaa gtccgtgtta tctcaacaac ggatttccca gaagaacgtt acaaaaaagg
    14041 aacggtgtta acactattcc aagacggaaa agcacctgtg gaattaacag tcaaaagtca
    14101 tcgcaaacat aaaaattttg acttattgag ttttgaagga catccttcta tcaatgatgt
    14161 ggaaaaatat cgggatggca tattaaaagt gtcaaaagac aactctgtag atctagctga
    14221 aaatgaattc tattaccatg agatcatcgg tctgcatgta ttagaagatg gaactgagtt
    14281 aggtaaagta aaagaaatct tgtcaccagg tgccaatgat gtttgggtcg ttcaacgtcc
    14341 gaaaaaagct gatatattgc ttccatatat cgcttctgtc gtcaaagaag tcgatttaga
    14401 agctggagtg gtccgtgtag aaattccaga aggactgatt gacgatgaag attgatgtat
    14461 tgactttatt tccaagaatg tttgaaggtc ctatggggga atccatcatc ggtaaggctg
    14521 tagataaagg attattagat atcaatatct ctaacttccg cgattattca gataacaaac
    14581 atcagacagt agatgattat ccatacggcg gtggagcagg tatgctgctc aaagtccagc
    14641 ccatctatga taacatccaa gccattgaaa aagctgcacc ggatgtcaaa aaaagagtaa
    14701 ttcttcttga cccagctggt aaacgattcg atcagaaaat ggcagaagaa ttttcacaag
    14761 aagaacactt agtattcatt tgtggtcatt atgagggata tgatgaacgt atccgcacat
    14821 tagtgacaga tgaagtttcc ttaggagatt atgtccttac tgggggagaa ttaggtgcga
    14881 tggtcatgat cgatgcaaca gttcggcttt tgccagatgt gttagggaat cagacttcag
    14941 ctcaaacgga ttcttattca accggtttat tggaacatcc ccaatatact cgcccggcag
    15001 aatataaagg gatgaaagta ccagaagtat tgacaaatgg aaatcataaa ttgattgaag
    15061 aatggcaatt aaaagaatca ctaagaagga cctatcaacg tcggcctgat cttttggaaa
    15121 cacttgaatg gacacctcaa atgacgaaat ttttagaaga aatcaagaaa gaagaacaag
    15181 aaaaaacagc agatgaagcc aagtgacttt ttctaaaata ttctttacag taggttgata
    15241 atatgttagt attttatggt gagtgcaaaa gcacttaact attacgatat tccgctatga
    15301 gaaaagctca taagaatatt tggaataagg agaagaaaac catgaatcca ttaatcgaag
    15361 aattaacaaa agaacaatta cgttctgaca tcccagcgtt ccgccctggt gacactgtgc
    15421 gtgttcacgc aaaagttgtt gaaggtactc gtgaacgtat ccagttattt gaaggtgttg
    15481 ttatcaaacg ccgcggtgct ggaatcagcg aaacttatac agtacgtaaa gtttctaacg
    15541 gagtgggcgt tgaacgtaca ttcccattgc atacaccacg tgttgcaaaa atcgaagtag
    15601 ttcgctacgg taaagtacgt cgtgcaaaat tgtactacct acgtgcatta cacggaaaag
    15661 ctgctcgtat caaagaaatc cgtcgttaat cattgttatc agactgagaa agaacccttg
    15721 gtattcaagg gttctttttt cttagcatgt aatttgaaca ccctgatcca gtttttttct
    15781 ttaattattg gtaggggaga ataatggatt agaataaatc tacctataag tagtagtaaa
    15841 aaaaagagca ctatgataat atctttctta agagtaaccg ctttaataaa aaatccagaa
    15901 tattctaaca taaatggagt attcttagaa tcaaaaggag aaagaagatg gtttatactt
    15961 atacggagca agaaaaaatg aaagtttgag acacattcat gaatgatgga aaagtaaaac
    16021 aagtaccaag ttcaacaaaa aagaaaaaca tcctattgaa agaagtcttg aaacgctttg
    16081 accatggagt gacttataca gaaacagagg ttaattcgat actgctgaac gtattttcta
    16141 gtggcgatta tgtcgaacaa agacgttatc taatcacatt tggctttttc aaaagaagtt
    16201 cagacggtcg ggcatatcag atgatgggaa ttgaaaatta gaagttttaa tttatactca
    16261 ttgaaaaaag ttcaagtatg cgatattggt tctacaccgc atacttgaac tttttttgtc
    16321 atctgtatct ataatacaaa gccaagaacg ttattcaaaa tatggatagc tatgataaaa
    16381 gctaatgagc gattcgcagt taaataagca atcgtcagta aaatcgttcc aggagcgtac
    16441 atgaaaaaat caattggatg cgttacatga ataaagataa ttctctttta tttgtacgaa
    16501 taaataccaa aacgtacctc ctaaaattag attcaaagaa gatagcaaag aggaaaaaga
    16561 tagttctgca gcagctatag cggcatgtgg attgctagaa ctttccaaac aactgcctgt
    16621 ttcagatcct cgtcatttcg attacgaaga gatagcaatc aaaatcttgg aagaattaca
    16681 gaaaaactat acaacgaaac gagttaacgg atcaaacggt ctgcttctcc atgccgttta
    16741 tgataaaaac agcttaaaag gtgtagatga atgtgtgatc tggggcgatt acttttatgt
    16801 agaaggaatc actcgtctag ctaaaacatg gtactgttac tggtgatgta taagagaaga
    16861 ggaggattca tataatgaag cgatggaaaa aaatgatgat tggatcaata gttttaggaa
    16921 tgtcactcgt atttggtgct tgtggtaatc aagaagacag tagtgaagaa tcagcaaatg
    16981 aaattaccgt ttcgacatgg aattatgaaa caacacctga attcaaagcg ctctttgaag
    17041 cattcgaaaa gaaaacggga atcaaagtga aagcagtaga tattgcttca gatgattatg
    17101 atacgaaact caccacgatg ctttcttctg gagacacgac agatgtattg acgatgaaaa
    17161 atcttttgtc gtattcaaat tatgctttac gagatcagtt agtcgatcaa acagaacgaa
    17221 ttagagaatt agacactgat gctgctgaag aaacatatga aatgtatgat atcgatggaa
    17281 aaacatatgc attgccatat cgaacggact tttgggtact atattacaat aagaaaatgt
    17341 ttgatgatgc aggaatcgaa tatccaaaaa atctaacttg ggacgaatat gaagatttag
    17401 caaaaaaact tagtaaaaat gacggacaag tttacggagc atatcaacat atctggcgtt
    17461 cgacaatcca agctattgca gctgctcaaa acgaggcgaa tcttgttgaa ccagattatc
    17521 aatatatgac tgattattat gatcgagcat tgaggatgca aaaagaaggc gcgcagatgg
    17581 attttggcac ggctaaatca acgaaagtaa cctatcagtc tcaatttgaa gaacaaaaag
    17641 cagcaatgat gtacatggga acttggtata tggctggcat actcgcaaac aaagaagcaa
    17701 gtaagacaga agtagaatgg ggaattacag ctattcctca gaagaaaaaa ggagaatcgg
    17761 tcacgacgtt tggctcacca acagcatttg ctgtcaataa aaactcaaag aaacaaaaag
    17821 cggcgcaaga atttattgaa tttgcagcca gtgaagaagg agcaaaagta ttagcaggag
    17881 taggagtagt tccttcatat cgtacggatg agattgatca gctttatttt aatctcgctg
    17941 gaatgccaac ggatgaaatt tctaaaaaag ctttttctcc tgatgaaatc aaacttgaat
    18001 ttccgattga tacgtatggg cctgcaatcg ataagatttt acaagaagaa tatgacttag
    18061 ttttggttgg agatgaaacg ccggaaaaag gaacggtaaa tatggagaaa cgtgtagctg
    18121 cggaaaaaga ataatcatga aaggagagaa gccaagagat aaaacactct tggtttcgtc
    18181 atcgaaatgg agaatagtat aaataagaaa gctacaaatc atttgcgtag aaaacgaacg
    18241 tggatcgctt attcgtttat cgccccgaat ttcattggtt ttttcgtttt tacattaata
    18301 ccaatcctgt tttcgcttgt actagcattt atgaaatggg attctttttc aacgccagaa
    18361 tttgctggac tagataactt tcgtaaaatg gccaacgatg agacattttg gatttctttg
    18421 aaaaatactt ttttatatac cgctgctgta gtgcctggca cacttgtttg ttcgttaggg
    18481 ctagctttac tactaaatca gaaaattaga gggatgaagc tttttcgtac gatatttttc
    18541 tttccgtatg ttacttcctt agtagcaatt gctgttgttt ggaatatgtt gtttcatcca
    18601 acagtgggac ctattaatat ctttttaaga cgatttattg aacatcctcc aggttggact
    18661 tcaagttcaa attgggcgct ttgggcaatt gtaattgtca gtatttggcg agggatgggt
    18721 tattacatga ttctatacct tgcaggacta caaagtatcc aaaaagaact atatgaagcg
    18781 tcttcgctag atggagcaaa ccgttggaaa caatttttga atgtgacatt accttcgttg
    18841 agaccaacaa ccttctttgt aacgatcatg cttgtcatca attgtttcaa ggtgtttgac
    18901 cttgtgcaag tgatgacgga tggcggccct ggtcgagcga caaatgtgct ggtttaccaa
    18961 atctacaatg aagcattcaa aaaatttgat tttggttatg cttcagctat ttcacttgtt
    19021 ttgttcgtaa ttgttttggg cgttacggtt gttcaatttt cttggaataa gcgtcgtact
    19081 taggaggtgt gatatggaag agagtgttcg aaatgaaaga aaaaaagcaa aaattcgttc
    19141 aaaaaacatg ccctttattc aatggttggg tatgattctg ctgattgtat tagctttatt
    19201 gacgatcatt ccttttttat ggatggtttc tgcttcattc aaagcaaata atgaagtgtt
    19261 aacgattccg attcaatgga tccctaaaac ttggcattta gagaattatc tggttatttg
    19321 gtctcgtatt cctttagtga cattttttaa gaatacagct tttttaagcg ttgtgatcac
    19381 gttgattcag ttgtttactt ctagttttgc tgtttacggg ttttctgaac taaattttaa
    19441 agggcgcgat attttatttt tagcatatat cggcacgatt gctgtccctt ggcagtctta
    19501 tatgatcccg cagttcatta tgatgagaaa agtgggttta acagatacgt tgtggtcgtt
    19561 ggtgctatta caagcgttca atgcttttgg tgtgttcttg ttgaagcaat attacagtag
    19621 tatcccagat tctttatgtg agagtgcgcg gatcgatggc ttatcagagt gggaaatcta
    19681 tcgcaagatc attttacctc ttacaaaacc ggcgattgcc agtttgacga tcatcacatt
    19741 cgttaataca tggaacgatt atatggggcc attcatttat ttgtcttcta cggaaaataa
    19801 aacaatccag ttagggttga aaatgtttat tgggctattt gatgcagagt acgcattaat
    19861 catggctgcc tcagttgttt ctgttcttcc tgttgctttt atatttttag cgatgcaaaa
    19921 atattttgta gaagggatcg cttcatcagg aatgaaggaa taggaggtga ttatgaaaga
    19981 gcagcgtttt gacaaaaatg tttatatgga attcttttat tggttgtatc aatcattggc
    20041 aagtagcctt tgtttttggt gtgtcaatat cttgtatata gcagctgcgt tccttttgtc
    20101 gatagatgga aggaatgtct tttcctttat tttttcttta ctttttattg gtccaggttg
    20161 catcgtgatg ataggtatga cagaagaatt agcaaaagaa aaaagttttt caccagtacg
    20221 tttgttcata aagacgtttc gccaattttg gctaaaggga tttttttatt ggctatttgc
    20281 ttggatagtt agtgtgataa tgatttttga ttgtttcttt tttatacgtt tttcttatgg
    20341 aaaatggttg attccgttgt ttgttttact tgcttgtttt acttgcttgt ttatcagttt
    20401 cctttagcat caactgctgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag
    20461 ttctacggat agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt
    20521 tactattgac aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag
    20581 gtccttctat cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg
    20641 atctgtagac tttataaatt gaaactttca attaagaatg acagtttttt atgtaaaaac
    20701 tgtcattctt tttcattttt tgaaacatat ggctaaacaa atgaaataaa acatgctata
    20761 cttttgaatg aaacaggttt agaaactgta tcacttattt gtgattattt ctaactaata
    20821 attaaaaata aagcataaaa aggacgatgt tcaatggctg aaaaaatgaa acaaggttcg
    20881 aaatctgtag tagaaagttt gattaatcat catgttgatt atgtattcgg tataccaggt
    20941 gcaaaaatcg atggtgtatt taatgaatta gaggatcaag gtcctgaatt aatcgtgact
    21001 cgtcacgaac aaaatgctgc atttatggca caagcaatcg gacgtattac aggagagcca
    21061 ggagtagtta tcgcaacaag tggtcctggt gctagtaact tagctacagg tttggtaaca
    21121 gcgacagcag aaggtgaccc agttttagca attgccggac aagtaaaacg aagcgatcta
    21181 ttgaagttga cccatcaaag catggataat gcagcactgt tccagccaat cacaaaatac
    21241 agtgcagaaa tccaagatcc agaaacaatt tcagaagtga ttgccaatgc ttatcgtatg
    21301 gctaagagtt caaaaaaagg cgcgagcttt atcagtatcc cgcaagatgt agtggatgca
    21361 cctgtccaag gtaatgtcat caagccattg agcgatccta aattaggttc tgcttctgca
    21421 gatgatatcc gttacctagc tgaacgcatt agagaagcaa aactaccggt actattagta
    21481 ggtatgcgag gatcaagtga aaaagaaacg ttagccatca ggcaattagt tgaaaagaca
    21541 gcattgcctg ttgtagagac attccaagca gctggagtga tctcacgtga attagaagcg
    21601 catttctttg gtcgtgtggg tttatttaga aaccaaccag gagatatgct tttgaaacga
    21661 agtgatctag ttattgcaat tggctatgat ccaatcgaat atgaagcaag aaactggaat
    21721 gcggaaaaag atgcgcggat cattgtgatc gatgaagcgc cagctgaaat cgatcctttt
    21781 atgcagcctg aaagagaatt gatcggtgat atctcagcca ctcttgattt attgacaggt
    21841 tcattagagc ctcaacaagt gtcagaagat gcaaaagaat atttagcatc tcttcaagca
    21901 aaattaacgg agcgggacat tgttcaatca aaaggagaag caggtatctt gcatccttta
    21961 gaagttatta acacgcttca gtcaaaagta acagatgata tgactgttac cgtagatgta
    22021 ggtagtcatt atatttggat ggcacgccac tttagaagtt atgaacctcg tcatttgtta
    22081 ttcagtaatg gtatgcaaac gcttggtgtt gcattgccat gggcgatttc tgctgcattg
    22141 gtgcgtccaa atacacagat cgtatcagtt tccggcgatg ggggattttt attctctgcc
    22201 caggatttag aaacggcggt acgtaaaaaa ttgaatatcg ttcatttgat ttggaatgat
    22261 ggacactaca atatggtaga gttccaagaa aaaatgaaat atcagcgggc gtcaggtgta
    22321 gactttggtc cagttgattt tgtgaaatat gcagaagctt ttggcgctaa aggaatccga
    22381 gctacaagtg tagaggaatt agaaaaagct ttagaagaag gatttgcgac agaaggaccc
    22441 gtaattattg atattccgat tgattaccgt gataatgaga aattgggaga aacaatctta
    22501 ccagatcaat tctattaagg aagtgtcgac atgactgaaa aaatcttata ccagcacggg
    22561 acattaggag ctttgatggc cggcttgatg gatggaacag aaacgattgc tcatatatta
    22621 gaaaaaggaa ctctgggatt gggaacattg catgggcttg atggtgaagt catcttttta
    22681 gatggcgtag cttatcaagg aagatcagat ggctcagttg cccaattaga tggaagtgaa
    22741 cttaccccct atgcagcaat tacagatttt acgccagata ctagtttttc tgtctcaaaa
    22801 actgcagatg gagaacaatt gaaaaaagac atattagtaa gagaagccgg ggaaaaccta
    22861 tttttggcag tgaagataac tggattattc aaaaatatgc acatccgtat catgccgaag
    22921 caagaaaaac cttacagaag actagcaaaa atttcagagt ctcaaccaga attccaacaa
    22981 agcaatgtcc aaggaacatt agtcgggttc tttacgcctg aattattcca aggagttgct
    23041 gcagcgggat ttcacctgca ttttatcgat gatacacata catttggcgg acatgtaatg
    23101 gattttgaag tggctgaagg aaaagttgag attagccgca tctcgtccct tgtacagcat
    23161 tttccagttg atgatccgac ttttgttcac gaaacgattg attatgctga tttagcagca
    23221 gaaatccaac aagcagaata gaaaaagaca gcgagatgcg ttcaaggtga ttaacctgac
    23281 gtatctcgtt tttttgagga gaaaacctag cgtttacaaa aaaactgagc tataatcttc
    23341 tccatagatc aaaaaggagc ggtttttatc atgtggacag aaaaacagaa aaaagatgca
    23401 tacgaaattt tattattaca gcaacaagga ttattagaag cagaagataa ctggttagca
    23461 aatttagcaa attcatctgc attgttgaat gagactttgc ctgagactgt ctttgcagga
    23521 tattatttat tcgatggtaa tgaattgatt ttaggaccgt tccaagggcg agtttcttgc
    23581 acacgtatca agatgggaaa aggagtttgt ggagaatcag ctgaaaaaca agaaacattg
    23641 atcgttgatg atgtcaaaac ccatgcaaat tacatttcct gcgattcagc cgcacaatca
    23701 gaaatcgtag tgccaatggt aaaagaaggt aatttaatcg gtgttttaga tatcgattgc
    23761 ggagtaacga aagggtatga tgaaatcgat caagcatttc tagaaaaata tgtagatctt
    23821 ttattagcaa attttaatat aaatgctttt tcatttatta ataactaaaa tcgtctattg
    23881 aaacaaaaaa gaagagaaat caagaataaa aagagccgga aagacagtgg gcatttctgt
    23941 ttttcggttt tttt
//
LOCUS       DACDAF010000039        23829 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.039, whole genome shotgun sequence.
ACCESSION   DACDAF010000039 DACDAF010000000
VERSION     DACDAF010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.039"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(53..787)
                     /locus_tag="IVZ69_001440"
     CDS             complement(53..787)
                     /locus_tag="IVZ69_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HAP8183530.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1114..1524
                     /locus_tag="IVZ69_001441"
     CDS             1114..1524
                     /locus_tag="IVZ69_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HAP8183531.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1517..2218
                     /locus_tag="IVZ69_001442"
     CDS             1517..2218
                     /locus_tag="IVZ69_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HAP8183532.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2218..3804
                     /locus_tag="IVZ69_001443"
     CDS             2218..3804
                     /locus_tag="IVZ69_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP8183533.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3823..4044
                     /locus_tag="IVZ69_001444"
     CDS             3823..4044
                     /locus_tag="IVZ69_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HAP8183534.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4041..4802
                     /locus_tag="IVZ69_001445"
     CDS             4041..4802
                     /locus_tag="IVZ69_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HAP8183535.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5182..5691
                     /locus_tag="IVZ69_001446"
     CDS             5182..5691
                     /locus_tag="IVZ69_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HAP8183536.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5766..6305)
                     /locus_tag="IVZ69_001447"
     CDS             complement(5766..6305)
                     /locus_tag="IVZ69_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HAP8183537.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="IVZ69_001448"
     CDS             complement(6445..7056)
                     /gene="rpsD"
                     /locus_tag="IVZ69_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HAP8183538.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7372..8169
                     /locus_tag="IVZ69_001449"
     CDS             7372..8169
                     /locus_tag="IVZ69_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-nitrite transporter"
                     /protein_id="HAP8183539.1"
                     /translation="MNPVSPLFEKIDASIEKKANLFENSFSRYAVRAVLACLFLTLGT
                     AVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAELGTSNMLYMTVGVFRQRLA
                     LSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNFMLESIAVKLAKPSATILV
                     EGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLGYEHVIANFPAFTLTYFAS
                     HGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQSKSSYVD"
     gene            8197..8832
                     /locus_tag="IVZ69_001450"
     CDS             8197..8832
                     /locus_tag="IVZ69_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HAP8183540.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8852..9625
                     /locus_tag="IVZ69_001451"
     CDS             8852..9625
                     /locus_tag="IVZ69_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP8183541.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10033..10830
                     /locus_tag="IVZ69_001452"
     CDS             10033..10830
                     /locus_tag="IVZ69_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HAP8183542.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10808..11221
                     /locus_tag="IVZ69_001453"
     CDS             10808..11221
                     /locus_tag="IVZ69_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183543.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11205..13850
                     /gene="mutS"
                     /locus_tag="IVZ69_001454"
     CDS             11205..13850
                     /gene="mutS"
                     /locus_tag="IVZ69_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HAP8183544.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13868..15976
                     /gene="mutL"
                     /locus_tag="IVZ69_001455"
     CDS             13868..15976
                     /gene="mutL"
                     /locus_tag="IVZ69_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HAP8183545.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15998..16558
                     /locus_tag="IVZ69_001456"
     CDS             15998..16558
                     /locus_tag="IVZ69_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HAP8183546.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16643..18631)
                     /gene="treP"
                     /locus_tag="IVZ69_001457"
     CDS             complement(16643..18631)
                     /gene="treP"
                     /locus_tag="IVZ69_001457"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HAP8183547.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18854..19567
                     /gene="treR"
                     /locus_tag="IVZ69_001458"
     CDS             18854..19567
                     /gene="treR"
                     /locus_tag="IVZ69_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HAP8183548.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19644..20090
                     /gene="msrB"
                     /locus_tag="IVZ69_001459"
     CDS             19644..20090
                     /gene="msrB"
                     /locus_tag="IVZ69_001459"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HAP8183549.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20260..20862
                     /gene="ruvA"
                     /locus_tag="IVZ69_001460"
     CDS             20260..20862
                     /gene="ruvA"
                     /locus_tag="IVZ69_001460"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HAP8183550.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAIEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20875..21876
                     /gene="ruvB"
                     /locus_tag="IVZ69_001461"
     CDS             20875..21876
                     /gene="ruvB"
                     /locus_tag="IVZ69_001461"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HAP8183551.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21905..22483
                     /locus_tag="IVZ69_001462"
     CDS             21905..22483
                     /locus_tag="IVZ69_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP8183552.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22535..23017
                     /locus_tag="IVZ69_001463"
     CDS             22535..23017
                     /locus_tag="IVZ69_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HAP8183553.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23134..23508
                     /locus_tag="IVZ69_001464"
     CDS             23134..23508
                     /locus_tag="IVZ69_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183554.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7782 a         4285 c         5114 g         6648 t
ORIGIN      
        1 aaaaaaactt ggtacgcaat cgctgtacca agttttttta tttagctttt gattaagcca
       61 taaataataa tttatataag aatactgcta cgacaccagc acagataggt gctacaactg
      121 gtacccatgc atatccccat tgagaagaac ctttatgttt caatggaaga agtgcgtgta
      181 caagacgtgg agcaaagtcg cgggctgggt ttagtccagg acctgtagga ccaccaagtg
      241 aagcaactaa tgtccataca aggaaaccaa gtgctaagtg agctgtacca agattatctt
      301 ggaagaatgg tgcttttgta atacctaggg caccaaagaa taaaacgaat gaaccaaaga
      361 attcattgac gaaaccattg aatttagaac caacgctgtt gattgttgag aatgtaccta
      421 acacatggtt tacgtcttct gtttggtcgt agtaaggttt gtaacaagct actacgatca
      481 attgtccaat cgctgcacca atcaattgtg caatgatata aggaacaact tcagcccaag
      541 ggaatagacc attagatgct aaagcaattg taaatgctgg gttgatgtgg ttaccgctga
      601 ttccaccaaa aatcattgct ggcatcataa ccccgaatcc atacccgaca gcaatcagca
      661 tccagtcact gccatatcct tttgtacctt ttaaatctac gtttgctaca gcaccgttac
      721 ctagaacgat tagtaatgct gtaccaatca tttccgccgc aagacgggtc attagtgagt
      781 aatccataaa tacctccaaa agttataaaa atgcaaaaaa aaaagaaaca tcaacacgaa
      841 aagcatcggt gcagtgtttc gtgtcggaag gatttctgca gtcttaacaa atgtgaataa
      901 aaaaatgaat tccattactt ataagaaacc agaccaacag taaaactcca actcttttta
      961 aaagttctcc acaaatcacc aagcttaact ataaatatac caaaaaaaaa acgttttttt
     1021 tctcaaaaat tgtatcttag aaacagcatg ttttgaaact ttcagaaaag gtttgttagt
     1081 aaaatgaaag ctatacgtaa ggagtgttgt ttgatgaaat tttttcaaga gtttttcatt
     1141 attattttct tttctgtatt aggagaaggc atacggattt ttgctcattt acctattcct
     1201 ggaagtatct taggtattct ttttttattt ttagcatttg aaatgcatct tgttgatcct
     1261 gaaaaaatcg gagcaactgg tgatttttta ttgaataatc tagccatttt atttgttcct
     1321 gctggtgtag gtttattgga atattttgat gatattgctt cgatatggcc tgttttactg
     1381 ggagcagtcg tcgtgtgttc catcgtcacg atggttgcag cgggaaaaac ggcagaaggt
     1441 gtagaagctt tgctgggcta tgtccgtaag aaaaaagcag aaagggtatc tgtaaacgaa
     1501 atggaggaga atcaaattga ctgagttttt tgtgaatcca ttatttggct taagtttgac
     1561 tttaggagtg tacgtattat ctgacaaatt tttgcggaaa tataaactgc ctgttttgaa
     1621 tcctctcgta ttatcgattg ttgttattat cttatttttg catttttctg ggatcagcta
     1681 taaagactat aatatcgggg gcaatttttt gactatgctg attactcctg cgacagtggc
     1741 acttgccatc cctctttata aaaacttccg tttactgaaa gagaattttt atcctgtaat
     1801 ggctgcgatt ttagcaggaa tagtcgcaaa ttgcttggtt agtgtagggt tcggttactt
     1861 cttctctctt cataaagaga tggtgatctc attactacct aaatctgtaa cgacggctat
     1921 ttctgtcgat ttatctcata cgatgggcgg ggtgaatgcc gtgacacttg ctattgttgt
     1981 ctctacaggt atttttggtt cgctgatcgc cactcatatt ttccgcctat tcaagatcga
     2041 aagtccagtt gctcgcggtg tggcgttagg aagtacttct catgctattg gtacagcaaa
     2101 agcaatcgag attggtgaaa tagaaggaat catttccgga cttgcgatat gcgtcaacgg
     2161 aatattgacc gttttattgc taccgttatt ctttcagcct tttgctggct tgttttgatg
     2221 cgaaaaccac tattttatgc tacaataacc aaaacgttcg agcataaaaa aggagggaaa
     2281 gacgtgtatt tgtcttccga gtatcttaaa caatttgata aagatctata ttataagatt
     2341 ctcctcctag aaagttttga ggatcaagct tggcataccg ctgcacaatt agcgcaagtt
     2401 gttcagctgg atgcccgcag cgtgtcgaaa tacctgaacg agctgtctaa aaactatcag
     2461 cagtttagcg gtaagacaca ccctttgttt acaaaaaatc accgttctgg ttataacttt
     2521 tatgatacgc tcgattcaat tgaacatgag cgttttttga tctatctcgt gcaaagtacg
     2581 ctgaaattcc agttgctgca cgacattttt tttgaagaat tccatacaat gtaccaattt
     2641 gcgcaaaagc attacattag tgaatctact gctcatcgaa aaatcaatga atggaaacag
     2701 caactgcaaa cttacggaat tcggctgcaa cgaggtacat atatcgctca aggcgaagaa
     2761 gaaatcattc gactttactt gcatatgaca ttctggcagt tgtttcgagg gaaaatctgg
     2821 ccatttgaaa cgatttctca aatggacgta aagaatatgg cagaacatat catggctttt
     2881 tttaatgttc gtctgaacga gatcaaaaaa agacgattgg aatatatgct aggtgccttt
     2941 tttttaagaa aatcacagaa gcattatgtt gtattgaatg agaaaaaaag acggctgatt
     3001 tctgacaatc tgttgttcca gcgattttgc caggtcatgg agccggtatt tcctaattat
     3061 tttcaagtag aagacgagtt aggcgcatta tttcttgtac tgatgactcg tgaagaatat
     3121 tatagtgatc ctaagatacg gaagaaaatt tttgattttc atcaacaagc aaaaacaccg
     3181 ccctttacag ccctttcaga agcaaaagcc gctctttctc tttatcagga agagcagggg
     3241 ctgccagcag aaaatctaac cttcgaggca gaaaactatt tattcagcag tcattttttc
     3301 gcctatcttt ttcctaatgc gaaagaaacg attgatggca atagtagtga ttttattaat
     3361 catttagtta ttgaaaacaa ggaattgaaa caatggctcg tacatttttt tgaaagtaga
     3421 cacaaacatc ccaatcatct ggcatttaaa aatcatgcgt ttttgatggg gcggtatctg
     3481 actgtgttta aaacattagg agcctttact ccacagcttc caaagatcac gatcctttta
     3541 atgacagatt tcccattatt tgaagagcaa ctgttagagg agggattacg gacatttttc
     3601 cgtaatgagt atcagctgat ttttctgcca acagattatc gggggagaga agttgatctt
     3661 ctgatttcga caagtaaagt ccaccgcaaa ccatgggcgg atcttgacta ttttattgtg
     3721 actgaagaac taaaattaat tgattacatc caactatctc aaaaatttga aatgattcaa
     3781 aaacaaaaac tattaaaaca ataacaaaga aggagaaaaa agatgacatt tgaagaaatt
     3841 ttaccagaat tgaaaaaagg tgcaaagatt attcgtaaag gatggagtgg atttgaactt
     3901 tatgttgttc tcgtatccga tgatgaattt gatggctgtc cggtgacgcc gtacttattg
     3961 atcaaaacaa gtgacgaagg tttttccagc ttcgctccta cagtttgtga tattttagca
     4021 gatgattggg cgatcgtaga atgaaaaacc agtatccaga tctagctaaa caggttgtat
     4081 ttatcacagg agctgcttct ggaattggtg ctgcgcaagc ccgagcgttt cttgaacaag
     4141 atgcttttgt atttggatta gatcaaaagt tcggtaaaat ggaagaaatt tctttgcgat
     4201 ttcctgaaac ttttgcctac gcactaggtg atgttcgaca aatgaaagaa ctccaacaag
     4261 cggtatcgaa atgccaaaat cattttggtg aagttacgat tttactgaat acagcgggga
     4321 tattggatgc ctacaaaccc ttgatggaaa ctgacgaatc gctgtgggat ctgatttatg
     4381 agacgaatgt gaaaagcatg tatcagctga caaaaatcat ccttcctgat atgatccgcc
     4441 aaaaaagcgg aacgatcatc aatatggctt cgattgctgg cttgattgct ggtggaggtg
     4501 ggatcgctta tacaagcgcg aaacatgcga ttgtcggatt taccaaacaa ctcgctctgg
     4561 attacgcagg acagggtatc cgagtaaaag gaattgctcc aggagccatc caaacaccaa
     4621 tgaatgcggc tgattttgaa gggaaaggtg agatggcaga gtgggtggca aatgaaacac
     4681 cagtcaagcg atgggcacag ccggaagaag tagctgagct gacgttattt cttgcctctc
     4741 ctcaagcaag ctacatacaa ggaacgatca tcccaatcga cggcggatgg ttgttaaaat
     4801 aaccttgtgt ttttttcaag cttctgtatg ataaaactaa agagagaaac aacggttgat
     4861 gataaaaaaa gtcgatgact gttcccgaca ttcgatgccg aacagccagt tcaaaaaatt
     4921 ctttttaata atcgttaata ttcgaaacta agcggctttt cacgacctct tgatataaac
     4981 gatattcaaa agcttgcaac tgcggtaaca agtccagcca aatgaaaaat ataaggagct
     5041 atttttattt gaccattctt attacttgtt gcagggcagc tttttcacta ccttctgcga
     5101 cacttcagtt ggaattttct tcccatcctt tggtcgcggt cattaccaag ataaaattat
     5161 cttgcaaagg agaaatagaa catggaaaaa aataataccc gttcagccaa acgctggaca
     5221 acgacagatg tgactcggat ggcgctagtc actggtttat atgtggcagt gacgctggtt
     5281 ttgtctgtct ttagctttgg agtgattcag attcgtctct cggagatgtt caactatctg
     5341 tccttgtata acaaaagata catcgtcgcg gtaacagcgg gagtagcttt ggctaatatt
     5401 gcttctcctc ttggactgat agatgttgca gtaggaagcg tcagcacgct gcttgtattg
     5461 cttatcaact ataaaatcac tagtcgcatc aaaaacatga aaatcaaaat ggccgtgaca
     5521 gcatgcgtat ttgctttttc catgtttaca gtagctggtc agctaacgat tttatatcaa
     5581 ctaccttttt tcttgaattg gtgggtgatt gctttaggag aattggcatc aatgattgtc
     5641 ggtgggataa ttatttattg gatcggtaaa aaagtggatt tgtcaaaata aagatctgtt
     5701 taatttaaaa tagggcagca tggaagagac tgaatgttga gtcttcttcc atgctgcttt
     5761 tttgattaat ttgtatgaag aaatcgattt agccgttttt tcatcaagat accgatataa
     5821 gctgctccag ttgccttgat tgcttccggc agtaaaaacg gcagtagtcc actggcaaat
     5881 gcagttgtaa aagtaagatc accacttatt ttcagccaga tcgttccgca gatcaatgca
     5941 gcaagagagc ccattagatt ggcaaagatt gcatataagt aatgagcatc cgttctttcg
     6001 atcatccaac cagttatcca cgtttgtaag agaaatccaa tcaaatatcc gccagttggc
     6061 ccaaataaaa cagctatacc tccagtcatc cctgaaaata caggaagacc aatcaagcca
     6121 agtaaaagat aaactccaac agatatcaat cctagttttc ttccgagaaa agttgctgtt
     6181 aatccaatag caaatgtttg ccctgtcaaa ggaaccaaac caaaaggaat ggtcatctga
     6241 gaaaggacag aaataatcgc ggcaaattcc gcagcaagta tcaattcttt caatgttcgg
     6301 ttcataacgc cctcttttcg ttaacttaat atttttattt ggttaacgaa attgtaaaac
     6361 aaagtgatta ctttgtaaat agaaaatata aaaaaagacc agctatccaa tagatagcgg
     6421 tctttttcaa gaaagctttt gaaattataa gctttggttg tagtattcaa cgacaagagc
     6481 ttcgtcgatt tctggatata gttcgtcacg ttctggtaaa cgagtcaatg aaccttccaa
     6541 tttttcagcg tcaaagctta cgaatgctgg gcgtccaaca gttgcttcta cagcttcttt
     6601 tactgttacg atgttttgtg atttttcacg aactgagatc acttgaccca cttctacgtg
     6661 gtatgaaggg atatcaacgc gtttgccatc aactaaaatg tgaccatggt taactaattg
     6721 acgtgcttga cgacgagtcg ttgcaagtcc taaacggtaa acaacattgt ctaaacgttg
     6781 ttctagtaag atcatgaagt taacaccatg tttaccttct ttgattttgc tagcttttac
     6841 gaacaagtta cggaattgac gttcgttcat tccgtacatg tgacgaagtt tttgtttttc
     6901 agttaattgc atgccgtatt ctgattgttt gccacggcta ttaggtccat gttgacctgg
     6961 tgcgtaaggg cgacgtgcta attcttttcc tgtgcctgac aatgagatgc ctaagcgacg
     7021 agaaattttc catgatggtc ctgtataacg agacattaaa atttcctcca atgaatataa
     7081 gtttttggag taaaataatc cgttgaaaaa ttcataatca tatagtttgt tcttcaatct
     7141 tcacctttgc agccgcggtt acacaatcga acccgagacg gggcaacaaa ctagggatga
     7201 gttattattt ttctgctgca ttattttaca caaattacag tatatgatag atcatccacg
     7261 aatgtcaaga taattagtac ataaaaacgc tttacaaacc taggctgtct ttataaaatg
     7321 agagggtatg tgcaaatgga aaaaagcgaa ggaagtttaa ggagaaaatc aatgaatccg
     7381 gtatcaccat tatttgagaa aatcgatgct tcaattgaaa agaaggcgaa tctttttgaa
     7441 aacagctttt cacgttacgc tgttcgagcg gttctcgcct gtttgttttt gactttagga
     7501 acggctgtgg catttgcgat cgcgatgaag ggggaagata tcgcgcatgg tctaggaaag
     7561 attttatacg catttatgtt cagctggggt ctggtcatga ttctatacat gaacgccgaa
     7621 ttaggaacat cgaatatgct ttatatgacc gtgggtgttt ttcggcagag acttgcttta
     7681 agtaaggcag ccaagattct atttgcctgt atttttttca atatgattgg cggtatatta
     7741 tgtggatttc taatttctat gactacgcca tttcaagatt taacgttgga caactttatg
     7801 ttagaatcaa tagcagtaaa actagcaaaa ccttcagcaa cgattttggt ggaagggatg
     7861 tttgcgaata tcgttgtcaa taccgctgta ctgatcagca tgcggatgaa agaggatgtc
     7921 ggaaaagtga tcacagtcgt attcatcatt ttcatttttg cttttttagg atatgaacac
     7981 gtgatagcga attttcctgc ctttacgctt acttactttg cttctcacgg acagatggat
     8041 ggaatgacag tcagcaatgt gttacataat ttgttttttg ctttggcagg aaattatatt
     8101 ggtggcggtt tagtaatggg actgggatat gcttggctga atcagtcaaa atcatcctat
     8161 gtggactaaa aagtcgttca ttaaagggga agtgccatgg aagttttagt ttttccaaaa
     8221 aatgaggaaa aagcgttaca aatggaaaag tacatgaaaa atcttttttc ctttgctgga
     8281 gtacctaagc cggaacgcgc tcttttacaa caaccgttac tggatgagag caaaaattta
     8341 tctatttctg aagttttagc ttttgttcat tattattatg aacaaatcga aagagagtat
     8401 cagtatgtag cgatcgattt agtccagaaa aacatcaaac ggcttacatt tgaagactta
     8461 gtcgtattgt tgccactagt tcagaaaaaa gaatggtggg acagcatcga ctcttggaga
     8521 aaagtataca gcacatggtg taaagcctac ccagagcagc gtgaagaagt ctttcaattg
     8581 tttgaaaaaa aggaagattt ttggctacgt cgaatagcaa tcacgttgca attaggttat
     8641 aaacagcaaa cagacacagg actattgatc cgagcaatag acgaagatcg tcaaacaaag
     8701 gaattcttta tccaaaaagc aattggttgg gcattacgcg attatagtaa gaccgatgcc
     8761 gattgggtaa aaagacagct gacaacagat ttgagtaagt tagctgttcg agaggcaagt
     8821 aagtatttat aagaaagcga gacgacaaga gatgagacgc aaattatttg cttttgatat
     8881 tgatggaacg ttgttagatt caaacaaaca agctttagat agcacaagag aagcattgga
     8941 aaaattacgc aaagccggtc atctggtcac gattgctaca gggcggagcc gatttcatgc
     9001 gcaagagatc attcgcgatc ttgattttac gaactacatt ttatgtaatg gagcggccgg
     9061 ttttttagac catgaacaag tatataagaa tttactagat cgcgaccagt tggatgcgtt
     9121 cgttcaagaa gcgcatcatg agcagatcga tacagctttt gtcagcttag acaatatcaa
     9181 gcgttcttct tccaatgatg taacggtgat ggaagaagcg atgcattctt tcggtgctgt
     9241 cttgcctgaa ttagatcagt tttttgcaga ggaacaagaa atataccaag cgttagcatt
     9301 tttcgatcaa acatatgatg ggaagttctc ttcatatgat aaaattcgat ttgtccgctg
     9361 gcatgagaac agtgtagatg tcgtacctaa aaatggttct aaagcagcga caattctgca
     9421 cttagcagaa caagtaggca tccctcatga agacatcatc agctttggcg atggacaaaa
     9481 cgaccgtgaa atgttgcgca tgtcaggaat tgggatagct atggggaatg ctgtgccaga
     9541 agtacaagca gaagctaaga tggtcactga tacaaacgat caggatggaa tttggaaggc
     9601 attgaaagag ttaagcgtga tttaaaagag gttgtgaaaa agctgttctg catcaagtaa
     9661 taagcccagc caaacaaaaa tagctcctcc tatttttcgt ttttctgggc ttattaccgc
     9721 agatgcaagc tttcgaacac cgtttaagga agaggtcgtg acagaagtgg tcagtttcaa
     9781 gaaataagaa gggatttacg aaaattgctt ctcaaatttt tgtaaaatta cggcttattt
     9841 ctgaagaagt agatgaaaca acgtttattc gggaaatggg actgtgacaa gatgtttgtc
     9901 atagtcccat ttttttattt tatttttcaa aactaagaaa taccaggaaa gagttccttt
     9961 tgtttgacct tttctttctt attgaaaaca actataatat agagtgatgt taaaagagaa
    10021 gaggaattta gtgtgcgggt attgtttatt ggtgatgtag taggttcaat gggacgagag
    10081 atgattactg aatatcttcc tagattgaag aagaagtacc gtccgcaagt aacgattgta
    10141 aatggtgaga atgccgcttc tggacgtgga atcacagaaa aaatctataa aaaatttttg
    10201 caagacggcg tagatgtcgt gacgatgggg aatcatacgt gggacaaccg cggaatcttt
    10261 gagtttgtaa atgaagctaa aaagatggtt cgtccggcaa attttccgga agggacgcct
    10321 ggacaaggga tggtctttgt caaagtgaac caagtcgaac tggcagtgat caacatgcag
    10381 gctcgttctt ttatggtgga cttggatgat ccttttcgta aaatgaatga gctggtagaa
    10441 gaagccagaa aacgtacgcc gatcattttt gtagattttc atggagaaac aacaagtgaa
    10501 aaacaagcaa tgggctggtt tttagatggg aaagtttcag cagtggtcgg tacacataca
    10561 cacgttcaga caaatgatgc gcgaattttg ccaagaggaa cagcgtatct gacagacgtt
    10621 gggatgacag gtccctatga tggtattttg ggtatgcgca gagaacctgt aatcgaaaag
    10681 tttctgactg cattaccaaa acgttttgaa gttgtggaac aaggccgatc gattttaagc
    10741 ggctgtatct tggaattgga tgatacgaca ggtcatgcaa aagaaatcca gctgattcag
    10801 atcaacgatg atcgaccgtt catggagtag aaagagaggc agttttttgc agcaggagcc
    10861 ggaaattcaa aaagaagtaa ggaaactgac aaaactttta agagagaatg aaacgatcat
    10921 tcgctacaaa gaacttgaag aaaagatcca gcaaaaccag tatttagctg agttgagaga
    10981 aaaaatcaaa caagcgcaaa aagatgctgt tcattttgcc cactatgaca aaccagcagc
    11041 agaaaaagaa gcaatcaaac aagcggatca attcatgcaa gaatttgatc agcatccgct
    11101 tgttgtagct tatagaaaac agctgttgga agcagatgat ctgcttcatc atttaacaac
    11161 tatgatacaa gaagaaatca atggacaaat agaggaggaa aaacatgcct caaaaaacta
    11221 aaaatactcc tatgatggaa caatatctaa gcatcaaggc ccaataccaa gatgcttttt
    11281 tgttctatcg tttaggagac ttttatgaac tattttacga agatgcgatc aaagcgtcac
    11341 agcttttgga attaacgttg acgagcagaa atcgaaatgc agaagaacct attcctatgt
    11401 gcggtgtacc tcaccatgca gcacaaggat atatcgatgc cttgattgaa aaaggctata
    11461 aagtagcgat ttgcgagcag gtagaagatc caaagacgac taaagggatg gtcaagcgcg
    11521 aagtgatcca gctagtcact cctggtacag tcatggacag caaaggattg tcggcaaaag
    11581 acaacaattt tttaacagct gtagttagtc aaggaaatga atttggcttt gcttatgccg
    11641 atttaagtac gggagaattg aagacggctc ggttgcatga tgaagaagct gttttaaatg
    11701 aagcctctgc attgcagaca aaagaactcg tattaggcag tgagatcact gatacccttc
    11761 gtgaacagct aagcgggcgt ttagggctag tcttttctca acaaaatgag atggaagaaa
    11821 acgcggaatt tagctttttg acaagcgaac tagtcgatcc gctggaaaaa gaagcaaccg
    11881 gcaaactatt gacttattta tcggtgacac aaaagcggag tttagctcat atccaaaaag
    11941 cagtagaata ccaaccagat cattttttga aaatggatta ttattcaaaa ttcaacctag
    12001 aattaagcca atctattcgg actgggaaaa agcacggcac tcttctatgg ttgttagatg
    12061 aaacaaaaac agcaatgggt ggccgtttac taaaacaatg gctagaccgt ccgcttatcc
    12121 aggcaaaaca aattaaagca agacaagaaa tggtcgcttc tttgctagac agctattttg
    12181 aacgtatcga tttgcagtca gcattaacga aagtctatga tctggaacgc ctagcaggtc
    12241 gagtagcttt cggtaatgtc aatgggcgag acttgatcca gctgaaaact tctttagaac
    12301 aagtgccaat gatcagaggg ttgattgaag gaatcgatca aggtcaatgg caaagtctgc
    12361 tttcagaaat gcagccgatg gaccatctcg tccaattgat cgaccaagct atccaagatg
    12421 atccgccgtt acaaataacg gaaggaaaca tcatcaaaga tggattcaat gagcagctcg
    12481 atatgtaccg ttctgctatg agaaacggaa agaaatggtt ggcagaactt gaagcaaaag
    12541 agcgtcaaga aacaggaatc aagaacttaa aaatcggatt taaccgcgtt ttcggttatt
    12601 atatagaaat tacaaaagca aatcttggaa atgcagaact ggagaagtat gaacgaaaac
    12661 aaactttagc aaatgcagag cgtttcatca caccagaact aaaagaattg gagacacaaa
    12721 tcctcgaagc agaagaaaaa tctgttgatt tagaatatca gttgttttta gctgtgagag
    12781 aagaagtcaa aaaggctatc cagccgctac aagtacttgc aaaagcaatc agtgcagtag
    12841 atgtgctaca aagttttgca acgatcagcg aacgctatca gtatgttcgg ccagaacttg
    12901 tcagtgacaa gcatcagctt ctgatcaaag acggacgaca tcctgtagta gaaaaagtat
    12961 taggacatca ggaatatatc cctaacagcg tagaaatggc agaagacgaa atgatcttgc
    13021 tgattacagg accgaatatg tctggtaaaa gtacgtatat gcgacagttg gcattaactg
    13081 ttctgatggc gcaaatgggc tgtttcgttc cggcaaaaca agcagtttta cctatttttg
    13141 atcggatttt tacccgaatt ggtgcaagtg acgacttaat tgctggacaa agtactttta
    13201 tggtagagat gatggaagcc aatcaagccc tgcgttatgc tacgccaaac agtttgattt
    13261 tgtttgacga actagggcga ggaacagcaa cctatgacgg aatggcgttg gcccaagcaa
    13321 tcatcgaata tatccatcgt catgtacaag caaaaacact cttttctact cattatcatg
    13381 aactgacggt acttgagaaa gaacttccgc agcttaaaaa tgtccatgtt ggagccgttg
    13441 aaaaagacgg agaagttgtc ttcttgcata aaatgatgga tggacctgcg gataaaagct
    13501 acggcataca tgtggcaaag atcgcaggat tgccttccaa tctactagaa cgagcagcag
    13561 atatcctgca tacgctagaa aatggcgata acggacacca tactgttcca gctgaagtag
    13621 aagagaaaac taaaacagcc aaacaggagc aaataaaacc acctgcagaa aaagtaaatc
    13681 aagaccatat acaagaccgt gtaaaagaag aaaaccaaca gctttcttta ttcagtgaat
    13741 tatccgaaaa tgaaacagaa gtcattgaat cactgaagca aataaattta ctagaaatga
    13801 cgccaatgga tgcactaaac acattatatg aattacaaaa acaactgtag gaagaaggcg
    13861 gatatcgatg gccaaaatcc aagaattatc tgaacgttta gctaatcaga tcgctgcggg
    13921 agaagtagtg gagcgaccag cttccgttgt gaaagaatta gtggaaaatg caattgacgc
    13981 cggcagtact cagattgata tcttagttga agaagcggga ctgcggacga tccaagtgat
    14041 tgataacgga gaaggcattt tggcagacga cgtagagaat gccttcaagc ggcatgcgac
    14101 aagtaagatc cataatcgcg acgatctttt tcgcatacga acgctgggct ttcgagggga
    14161 agctttgcca agtattgcct ctgtttctga aatgactctg gaaacggcga atcaggaaga
    14221 aaaacaaggc acctatctgt cgctgaaagg cggagaagtt attgagcatc gaccagcacc
    14281 actgcgtcaa ggaacgaaga ttaccgtcag caatctgttt ttcaatacgc cagcccgctt
    14341 gaaatacgtg aaaacactgc acacagaatt agcgaacatc ggggacatcg tcaatcgact
    14401 ggcattgagt catccatcga ttgcttttcg tttagtacat gatggaaaca aaatgctggc
    14461 aactgctgga aatggcgatc tgaaacaaac aattgcggga atctacggat tatctaccgc
    14521 aaaaaaaatg ctgaaaatcg aaggaaaaga tctagatttt gagttatttg gctatgtttc
    14581 attgcctgag gtgactcgtg ccagtaggaa ttacttatcg acgatcatca atggacgttt
    14641 tatcaagaac ttttccttga ataaagcaat cgttgcaggt tatgggtcaa aattaatggt
    14701 cggtcgtttc cctattgctg tattggaaat caaaatggac ccgcttttag tagatgtaaa
    14761 tgttcatccg acgaagcagg aagtccggct gtcgaaggaa aaagaactaa cagagctaat
    14821 tagtaacgcc attcaaaaag cattgtctca agaaaatctg attccaagtg cagcggataa
    14881 tctacggttt aagaaaaaag tacctgatca gcctaaaaca gaacaaatcg aaatcgattt
    14941 gtcctacgct tttgaagaag aaaaacctaa aaagccaagt agtttgaatt ttgatcgaga
    15001 gacaggtacc tttttcgtag aagaactaaa gaacacattt gttgacagaa ttgttgataa
    15061 gtctgtggaa aatgttgaaa actattctgg tttttctgaa gaaaacacca cttatccaga
    15121 aaaaacagcg aaaacggtgg ataagtttgg tgaaaatgtt gataactttg tagaaaaaac
    15181 agtggaaaaa tctgaaaaga aagaatttcc cattgtggat aacatggaga aaacaaatga
    15241 agaacaagca gataaatccg tagaagagga tgaaaagatt tacgaggaag aattgacact
    15301 ccatcctgaa tttgatttca ctcaaggaaa cgacaaaaca ttagaacaag ccatcaagaa
    15361 attagaaacg gaaaaaccag tacaacgttt tcctcagttg gaatattttg gacagatgca
    15421 cggaacgtat ctttttgccc aaagtagcga tgggttgtac atcattgatc agcatgctgc
    15481 ccaagagcgc attaagtatg aatatttccg ggaaaaaatt ggggaagtat ctgatgatct
    15541 gcaagaattg cttgttccat ttgtgttaga ctatccaaac agtgatgctt tgaaattaaa
    15601 agagcaaaaa cacttgctag aagatgcagg gatttattta gaagaatttg gtcaaaacag
    15661 ctttattgta cgggcccatc ctacttggta tcccaatgga gaagaagaat cgattattcg
    15721 ggagatgatc gatatgctgc tgacaactgg aagtgtgagt gtaaaaaaat tccgtgaagc
    15781 aacagcaatc atgatgagtt gcaaacgatc gattaaagcc aaccattatt tgaatgaagc
    15841 acaagcacgt gtgctgctga aggatctggc acgatgcgaa aatcctttca attgtcccca
    15901 tggccgtcca gtattgattc actttaccaa ttcggatatg gaaaggatgt tcaaacgaat
    15961 ccaagacccg cattaagtca aagagaagag ggaaaacatg aagattgtat tagcatccca
    16021 atcaccaaga agaaaagagt tattggctca tatcgtttca gaattcgaga ttgaacctgc
    16081 tgatatcgat gaaacgccat ttccagacga acagcccgtc gattatgttc gtagaatggc
    16141 tgaagaaaaa gcacgaactg tctgggaaca agatgaaaaa gaagaccatt tagtgattgc
    16201 cagtgacacg actgttgttc tcaatcaaga gatcatgggt aaaccagaag atctggctga
    16261 ggctgaattc atgctgaaaa aactaagcgg ggaaacacat actgtatata cagctgttgt
    16321 tttaaaaaca aaggaacgag aagaacggat actagcagaa gcacatgtca ctttttatcc
    16381 tttgacagac gaagagatca aacgctactt ggagacgggg gattatgcgg ataaggcagg
    16441 ggcatacggc atccaaaatg ctgcgagtgt attcgtcaaa gaaatttctg gagattatta
    16501 cagtatcgta ggatttccga ttggtgctgt caatcaggca ctgaaaacat tcatttaaac
    16561 aaaaaagcgg actatctgat tttcgattga aaatccatga tagcccgttt tttttattga
    16621 aaagattact tatctactct gactaagatt ttacttcagc tttaccgact gcttcgcccg
    16681 ggcgaacaag tcctgattgg tcaagagaaa gtcctgcaac tttttcatta ttggtcaaag
    16741 caacaataat gtcagttttc ttgccagctt gttctatttc tggcaaatcc atttcagcaa
    16801 tcagggtctc tggtgtgaca aggtatcctt ctttcacgaa tacattgaaa ggaacaccct
    16861 ttagttcaac agtatctaat cccatgtgaa caagtacttc cagcccctca ttagaaagaa
    16921 taccaatggc atgttttgtt tcaaagacac tcgtcacttt accgtttact ggtgcataga
    16981 ctttgccgtt tgacggttcg acagcataac cgtcacccat cattttttgt gagaaaactg
    17041 ggtcatttac ttcagttatt tccttgatgg tccctgcagc gactgcgaat aatgtttctt
    17101 ttgttgcaac tgccgtacca gttgctgaaa caggttcgaa agactgtggc gttgctgttg
    17161 cgccatttgc tgtttgaagt tgtacatcag cagcattttc aggaacagca ggatcaatct
    17221 tattcaaaat tccctgacgt ctaaagatga tcgtcaagcc aaatggaatg atgacagcaa
    17281 tgatcattgc gatgatgaaa ggtacccatg tttctgcttg gatagctagt attcctggca
    17341 aaccgcctac tccgatcgcg ttagctcgaa cacccatcaa gttagcaaac atgccagcta
    17401 atccagagcc gaccattgca gcgacgaaag gatagacgta tttcaaattg attccgaaca
    17461 tagcaggttc agttacgcct aagtaacaag aaatcattgc tggaatcgag atttgttctt
    17521 cttttttatt cccacgatgt aagaagatga tggctaagac tgcagagcct tgggcgatat
    17581 ttgataaagc aatcatcggc cataaattcg ttgatccgaa atctgcaatc agctgcatat
    17641 cgatggcatt ggtcatatgg tggagaccag taatcactaa aggagcatac aggaatccga
    17701 atacggcact aaacaaccag ctgatagaag acgtcaatcc agtatttacg atatttgaga
    17761 tccagcttcc gactgtccag ccgataggac ctaaaataac gtgtgcagct aaaacagttg
    17821 gtaacaatga aaacaatgga acaaaaatca tcgagatcga ctgagggata tatttgcgga
    17881 agaagatttc tagatacgct aacataaacc ctgccagcat ggctggaata acttgcgctt
    17941 gataaccaat catctggact tgagcaaaac caaaatccca aaatggaata tctgctgcgg
    18001 ctgtggaagc tacactataa gcatttaata attgcggaga aactaacgta attcctaaaa
    18061 cgattcctaa tatttgtgta gtacccatct tttttgcaat actccaagtg atacctactg
    18121 gaagaaaatg gaaaattgct tcacccggta accacaaaaa ggcattgaca ccattccaaa
    18181 acttcgagtg ttcaacgatt gttccaccaa gactttcaaa ctggatacct tcaagtacat
    18241 ttctgaatcc aaggatcaat ccaccgacaa tgattgcagg aatcagtggt gtaaagattt
    18301 ctgctaaaac ggcaatagca cgttgaacgg gatgaaggtt ttgttttgca gctgcttttc
    18361 cttgttcttt ggaaacccct tcaactccag atactgcaac gaagtcgtta taaaaagtag
    18421 aaacatcgtt tcctatgatg acttggaact gtcctgcatt cgtgaacatc ccttttacgc
    18481 taggtatatc ttcgatcgct ttttcgtccg cttttcctgg atcattcagg acaaaacgca
    18541 tacgagtcgc acaatgacta actgcagcaa tattttcttt tccgccgata tcatgtaaca
    18601 gcttctcggc atctgcttga tattttgcca tatcaataaa cccctttctc ttaacttgtc
    18661 tatgcaagtt gtttcttcat ttactatact ttttttcgga gagaattgca agcgttttat
    18721 taaaaagtac gagagaaaat gatatcgttt taaaaagctt aaaataagct tttcttaaaa
    18781 ataggaacat tgaaatacaa aaagagctgt agtatagtga agaaatgatg gaagaacgag
    18841 tgagggaaaa aacatgaata agttcaatga aattttttta gatttggaac agaaaatttt
    18901 agcgaaagaa tatcctccgc attcgctttt acccagtgag aaccaattga tcaaaattta
    18961 tggtgtttca cgagaaacaa ttagaaaagc gctgaatctt ttgactacgg aaggttatat
    19021 tcaaaaaaaa caaggaaaag gttcgatcgt actggatcgg aatcgcttcg actttcctat
    19081 ttctggattg actagctata aagagctaca ggagacccaa cgtattccaa gtgaaacgat
    19141 catccatacg ttagaagaaa cagaagtgac aaaagcattg aacgagatca ctggctggga
    19201 gatcggtgcg cctgtttggc atttgatacg cgaaagaaaa atcaatggcg aagtagttat
    19261 attagacacc gattatctat taaaggaaat cgttcctatt ttaactccag cacaagcaca
    19321 aggatcgatc tatgaatatt ttgaaaatga gctttctttg acgattgctt acgcgcaaaa
    19381 ggagatcaca gtagaagaag taacggaaat catgaaaaca gcgatggatc ttcacgatga
    19441 cacttatgca gtagtagtca gaagcctcgt tcatctggaa gatacccgct gtttcgagta
    19501 ttctgagtcg gttcaccgat tagataaatt ccgtttcgtt gagtttgccc gacgccgaaa
    19561 agtgtaaata gttcaaaaga aagcaaattg ttggcatctg tccactttgg cgctatgata
    19621 ggatcacaaa gggggcattt ttaatggata aaccaataag accagaaaaa gaagaactga
    19681 aagaaaagtt atcacccatg gcttatgcag tcacacaaga aaatgcaaca gaacgaccat
    19741 ttagcgggaa atatgatgat ttttacgaaa aggggatcta tgtagatatc gtcagcggtg
    19801 aaccgttatt cagctctgca gaaaaatatg atgcaggttg tggctggcca tcattcagca
    19861 aaccaataac gaaaagacaa gtgcgcgaaa aagccgattt ttctcatggc atgcatcgaa
    19921 tagaagttcg aagcaaagaa gcagattctc atctcggaca tgtgtttacc gatggaccag
    19981 tagatcaagg tggtctacgt tactgcatca attctgcctc actgaaattc attccatatg
    20041 aaaagatgga tgaattaggt tatggggaat tcaaatcact tgtagaataa tggaaataca
    20101 caaagagcgg tacaatacgg ggatttactc gatcgtccgc tcttttttta ttcaagcgat
    20161 tgctatttga aagaaacgct ccctagactc cttttttcac aaggtgaaat gtgctacaat
    20221 aaagggaacg tatgtgtgca aaagaaagag gactagaata tgtatgaata tctgacaggt
    20281 gtggttacct ttatcaaccc ctattacata gtagtagaaa ccaatggtat cggctaccag
    20341 atcgcactag gaaatcctta ccgctacagt agcaaactaa atcaaaaaat aaaaatttat
    20401 gtccatcagg taatacgtga agatgcgcat cttctgtatg gatttgattc gctagaagaa
    20461 aagcaactgt ttttgcgatt agtaagtgtt tcaggaatcg gtccgaaaag tgcccttgca
    20521 atcatggcaa gcgaagacca ctccggtttg attcaagcag tagaatccag tgatgtcact
    20581 tatttgacga aatttccagg agtagggaaa aagacagcac aacaaatgat cttggatcta
    20641 aaaggaaaat tcggtgagct gagtatcgat acacctttta gtctatttga tgaagcaaac
    20701 acaaaagacg ctacagctct atctgaagca atagaagctc tctcggctct tggttacagt
    20761 gatcgagaaa tcaaacgtgt agaaaaacaa ttaaaagaag tagataatca gacaacggat
    20821 gagtatctac gccaagcact caagctaatg atgaaaaaat aaggaggaga ccaaatgaca
    20881 gatgaatact tgttatcacc agaatctggc gaaaatgaac tgagtttgga aaaatctctt
    20941 cgaccacagc tgctttctca atatatcgga cagagaaaag tcaaacaaga acttcagatt
    21001 tacatcgaag ctgccagaaa tcgggaagaa cctttagatc atgttctgtt gtacgggcct
    21061 cctggattag gaaaaacgac gatggccatg gtcattgcta atgagatgac cgtaaatatt
    21121 cgtacgacga gtggccctgc tatcgaacgt ccgggtgact tagtagcaat cttgaatgaa
    21181 ctggaagcag gggatgtcct gtttatcgat gagatccatc gattacctag agtggtagaa
    21241 gagatgcttt attcagctat ggaagatttc tatgtagata tcatggtagg acaagggcca
    21301 accgcacatc cggttcattt ccctcttcct ccctttactt tgattggcgc gacgacacgg
    21361 gcaggtatgc tttctgcacc tttacgagat cgatttggca tcatttctca tatggaatat
    21421 tatgacgaac aggatctgca ggagatcgtt ttacgttctt cggatatttt tcaaacagag
    21481 atcattgaag aaggggcatt ggaaattgct cgccgatcac gaggaacgcc tagaatcgct
    21541 aatcgcttgc tcaaacgggt tcgtgatttt gcgcaagtcc aaggagacgg gaaaatcgat
    21601 cgtcctatag cggatcaggc acttactttg ctacaggtcg atcaggctgg attggattat
    21661 gttgaccaga aattgttgcg aacaatgatc gagttatatg gcggcggacc agtagggtta
    21721 agtacgcttt cagtaaacat aggagaagag cgtgagacgg tagaagatat gtatgaaccg
    21781 tatctgatcc aaaaaggatt tttaaagcgt acacctagag ggcgaattgc tactgcttat
    21841 gcctatgaac attttggtta cgactatcat atatgatttt tgcttttaga ttggaggaaa
    21901 atgaatgagt gatacaacac gtacgaaaca attgatcaaa aacgtattga ttgatttgtg
    21961 ccaaacgcaa tcttttcgaa aaatcagcgt ccaaaaaatc gcaaacgaag caaaaatcaa
    22021 tcgacaaaca ttttattatc attttacaga taaatacgat ttgcttcgtt gggtctattg
    22081 tgaggatgca ttgcattatt tagatccaca atgtctttca cttgataatt gggaagagca
    22141 agcattgaaa atgctgaaag caattgctga gaagaaagaa ttttatgcaa atactgtgct
    22201 ttctgaccca gaaattttac aaaaagagtt ttctcaactg atccaaaaat catttatcaa
    22261 gatttttgaa caaatggatg aagaaagaca actttctgca agagacaaac tattttatgc
    22321 tcgttttttt tcttacggtt gcagtggtgt attagtcaat tggatcacga atgaatatga
    22381 agaaacaccg atggaaatcg ctatgcagct tttccgttta gccaaggata cggaattata
    22441 ttcttatcgt ctttatgcaa aagaagagtt ggaagaacag taatagaaaa attttttgtt
    22501 ggaaaagcaa taatcgctaa aaggagatgg ggaaatgaca aaaattttat ttgtttgttt
    22561 gggaaatatt tgccgttcac cgatggcaga aggcttgctg agaaaacgaa tagcattaga
    22621 aggaagggaa gcagaatttt ttgtggattc tgctgctaca agcacgtatg aagttggaaa
    22681 gacaccgcac cctggaacga aaaaaatatt aaaccaagaa aaagtagata tgacgaatat
    22741 ggttgctcgg caaatcacac cccacgattt tgaaactttt gattggatca ttggcatgga
    22801 tcaagaaaat gtagaagaac tgaaacgaag agcaccacgc tcagcgcagg ggaaaatcca
    22861 tttgttttta agtagcattc ctggaaaaga aaaagaaaat gttcccgacc catactatac
    22921 caataacttt gatgagacat atcacttgat cacagaaggc ctgaatcatt ggtggaatat
    22981 ttggattgat gaaaataaaa taacaaataa tttgtaaagt taacgctttc tttttaaggc
    23041 gatgttagag catttccttg tttttttgta aaatgttagg taaaataaaa ttaattaagt
    23101 aacactttct tagctaaagg aggagtgcat tcgatgaacg aagagacagt atcgccaatg
    23161 aagaagctta cgaagttagt tactcatact tcgtatcaac tttttgattc ttttgtaaat
    23221 gacactgaag aacatgctaa gaatgtacga ttgcaaggaa agtttattct tgagctgcaa
    23281 aaagctgcta ctgaacatag tctagttatc ttacaagtaa gagcaaatcg tttgagtagc
    23341 aagtatgaaa cgatctcagg ctgggtggcg acaaaaacgg tcgaaaaaga ccgagtgatg
    23401 atccgcctac aaaacgaaga gcagcagatc cggatggttc ctgtagaaca aattgaaaaa
    23461 ataacaatcc tttcaccagc aggggaacag gaacggttat caaaataatt tataccagat
    23521 agaaaagcac gtatgagctt gtaccatcaa tcattactaa tcaaaaataa ccgaatgctt
    23581 taagctgata tcagtaaaac ggaacgtttt aggatgagta tcatagcatg acagcattcg
    23641 gttgattagt tgaatcgatt ggatggtaca agtttttttg ataaaaaaag gtcctgctag
    23701 ccggggagct agcaggataa ggagttaaaa atgaaaaagt gttgttaggg ttgtttgttg
    23761 gtatgcttat ataatagtca ttagttgtga atattttgtg acgaaagttt tcgaaagttg
    23821 ttaagtttt
//
LOCUS       DACDAF010000040        23740 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.040, whole genome shotgun sequence.
ACCESSION   DACDAF010000040 DACDAF010000000
VERSION     DACDAF010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.040"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            299..1960
                     /locus_tag="IVZ69_001465"
     CDS             299..1960
                     /locus_tag="IVZ69_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP8183555.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(2030..2377)
                     /locus_tag="IVZ69_001466"
     CDS             complement(2030..2377)
                     /locus_tag="IVZ69_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HAP8183556.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2461..3402
                     /locus_tag="IVZ69_001467"
     CDS             2461..3402
                     /locus_tag="IVZ69_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183557.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3403..4446
                     /locus_tag="IVZ69_001468"
     CDS             3403..4446
                     /locus_tag="IVZ69_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8183558.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4452..5522
                     /locus_tag="IVZ69_001469"
     CDS             4452..5522
                     /locus_tag="IVZ69_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183559.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5512..6465
                     /locus_tag="IVZ69_001470"
     CDS             5512..6465
                     /locus_tag="IVZ69_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8183560.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6477..7487
                     /locus_tag="IVZ69_001471"
     CDS             6477..7487
                     /locus_tag="IVZ69_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP8183561.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7772..8593)
                     /locus_tag="IVZ69_001472"
     CDS             complement(7772..8593)
                     /locus_tag="IVZ69_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HAP8183562.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8690..8968)
                     /locus_tag="IVZ69_001473"
     CDS             complement(8690..8968)
                     /locus_tag="IVZ69_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183563.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            9236..11245
                     /gene="metG"
                     /locus_tag="IVZ69_001474"
     CDS             9236..11245
                     /gene="metG"
                     /locus_tag="IVZ69_001474"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HAP8183564.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11724..12311)
                     /locus_tag="IVZ69_001475"
     CDS             complement(11724..12311)
                     /locus_tag="IVZ69_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183565.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12486..13808
                     /locus_tag="IVZ69_001476"
     CDS             12486..13808
                     /locus_tag="IVZ69_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8183566.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13963..14739
                     /locus_tag="IVZ69_001477"
     CDS             13963..14739
                     /locus_tag="IVZ69_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HAP8183567.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14732..15301
                     /gene="rnmV"
                     /locus_tag="IVZ69_001478"
     CDS             14732..15301
                     /gene="rnmV"
                     /locus_tag="IVZ69_001478"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HAP8183568.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15294..16178
                     /gene="rsmA"
                     /locus_tag="IVZ69_001479"
     CDS             15294..16178
                     /gene="rsmA"
                     /locus_tag="IVZ69_001479"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HAP8183569.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16629..17258
                     /locus_tag="IVZ69_001480"
     CDS             16629..17258
                     /locus_tag="IVZ69_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183570.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="IVZ69_001481"
     CDS             complement(17382..18491)
                     /gene="ugpC"
                     /locus_tag="IVZ69_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HAP8183571.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18700..19122
                     /gene="mgsA"
                     /locus_tag="IVZ69_001482"
     CDS             18700..19122
                     /gene="mgsA"
                     /locus_tag="IVZ69_001482"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HAP8183572.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19445..19981
                     /locus_tag="IVZ69_001483"
     CDS             19445..19981
                     /locus_tag="IVZ69_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP8183573.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(20021..21784)
                     /locus_tag="IVZ69_001484"
     CDS             complement(20021..21784)
                     /locus_tag="IVZ69_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183574.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21787..23502)
                     /locus_tag="IVZ69_001485"
     CDS             complement(21787..23502)
                     /locus_tag="IVZ69_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183575.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
BASE COUNT         7658 a         4334 c         4810 g         6938 t
ORIGIN      
        1 tcagataagg gactgtgaca agacttttgt cacagtttct ttttgtttat tcttttttat
       61 ctttgtatgg caataataga caatataacg aaaattattt aatggctttt ggaagaccat
      121 ggaaaacctt gtacaaagct attttttctg aaaaattcct tgaaacctca cgaaaaaatc
      181 attattttat gaaaaagaca aaaaaaagtg ttgatttttt aataattatt cattaaactc
      241 ttaaacaact tcagaaaata ttaattattc tgaaaattcc aataaagggg tacgtaaaat
      301 gaaaaagaaa tttacatttg gtttggttgc ggtatgcggc cttgtacttg ctggatgtta
      361 tggcggcagt tcagccacaa gcagtagttc agcaaaaagc ggttcagcag atggaggagg
      421 cgtatttaac ttagtcgtgc ctcaagaaat gcctacagct gacttatcag ttgcaacaga
      481 tacaatcagt tttacagcat tgaataacgt ttatgaagga atttaccgtc ttgatgaaga
      541 cagcaaacca cagccggcag gagctagcga gttggcagaa gtcagtgaag acggattaac
      601 ttacaaaatc aaattacgag aagacgcaaa atggtcaaat ggtgatcctg ttacagcagc
      661 ggattacgtt tatggctggc aacgaacagt agacccagct acagcttctg aatatgctta
      721 cctgtatgcg ccagttgaaa atgcagaaga cattacagct ggaaagaaag ataaatcaga
      781 actagggatc aaagcagttg gtgactatga attagaaatc aaattgacga aacaaacacc
      841 atatttccaa tatctgcttg ctttcccatc atttttccca caaaaacaat ccgtagtgga
      901 agaaaatggg gatgcctatg catctgcaag tgataaagct gtttataatg gaccattcac
      961 attagaagat tttgatggac caggaacaga tacagaatgg acttataaga aaaatgatca
     1021 ttactgggac aaagatacag taaaactttc tgaaatcaaa gtcagtgtag taaaagaatc
     1081 ttctactgca ttgaacttat tcaaagatgg ccaagcagat gacgtgatct tgtctggtga
     1141 gttagcacag caaaacgcaa acgatccagc ttatacttct gttaaagaag cgcggacaag
     1201 ctatatcgaa ttcaatcaac gtgaaaagaa ttcaccattc aacaatgtga acctaagaaa
     1261 agctatttct tattctatcg atcgtgaagc tttagtaaaa caagtactag gtgacggatc
     1321 agttgtctct acaggattga tcccatcaga tatggtaaaa agtccaacaa cgaacgaaga
     1381 ctttgcaaaa gaagctggaa aattagtttc ttatgacaaa gataaagcaa aagaatattg
     1441 ggaaaaagcg aaaaaagaat tgggcgttga ttctttagaa tttgatttga tggcttctga
     1501 tgatgattca tcgaaaaaag taatcgaata tgttcaaaac tcaatccaag aaaacttgga
     1561 tggcgtaaca gtcaaaccaa cacctgttcc attctctgta cgtcttgacc gctcaacttc
     1621 gggtgatttt gacgcagtac taggcggatg ggctgctgac tatgcagacc caagcagctt
     1681 tactgatttg tttgtcacag gtaattcata caaccgtggt cgctggagca atgcagaata
     1741 tgacgaagca gttaaagcag cttcatcaac agacgctggc gatgaacaag cccgttggga
     1801 tgatttccaa aaagcaatca agatcatctc tgatgatatg ggtgtcgttc cggtgtacca
     1861 aaaagcagaa ggtcacctag tgaatgaaaa aatcaaaggt atcgttcacc atgcggcagg
     1921 cgcttcatgg gattacaaat ggacatacgt tgaagaataa tcgttaatac cgtgagcatg
     1981 agaaaaaacg aggctgcggc aaatgtcgca acctcgttct catattcact tatcctaaca
     2041 aagaaaaaag catgaaaata gcagaaagag caattagtat tccggcaatg atcagccaaa
     2101 agctgtacat accgtagctg gcagacgaga gcgaggaaaa ttctggtttt ttctttcggt
     2161 tccttgttcg tgcaagatgg accgatcgct gaaaatgatc gaagaaaccc gaagaaaaga
     2221 cccataaaaa accgccgata atcagaaacg gcaatgacca taagaataga tcattagata
     2281 attgaatgag tgtaaaggaa tggttgatga gattttttat taaaataacc agaatcagta
     2341 gaaaagctac tgcgtagggg atagattttt ttttcatttg attgctcctt tatttttggt
     2401 tcattatcta ataatgtagc gaaacatctg tcagaagtca aaagctaggg ggaaacatta
     2461 gtgaatagtt atatcaaata tgtattaaaa cgtgtctttt tcatgatcat cacgctttgg
     2521 ttaattgcaa caatcacctt tttcttgatg caattgctgc cgggcacgcc atatacgaat
     2581 caggaacgtt tgagtcctga aacaatcgag atgctaaata aacaagtcgg tttggataaa
     2641 ccagttatcg tacaatatgg gatttatctt tctaatttgc ttcaaggaga ttttggaatt
     2701 tccttccaat ttaaaaacca gccagtcgca catttgttag ctggaagaat cggaccatcc
     2761 ttgcagttag ggttacaggc aattatcttt ggaacagtcc tagggacgat tttaggaacg
     2821 atctctgcca tgaagcaaaa tacatgggca gatacatctt ctacactcgt agcgatatta
     2881 ggtcgttcca ttccaaactt tgtatttgct gttttattac aatatatctt tgcaatcaaa
     2941 ttacaagttt tgccaatcgc aaaatgggat ggctttgtgt acacaatctt accaacaatt
     3001 gcgttggcca tgtcgccgct tgctgactct gctcggttta tccgtacgga aatggtggaa
     3061 gtactgcata gtgattatgt ggaattagca aaagcaaaag gattgagccg ttgggaaatc
     3121 gcctttaaac atggtcttcg aaatagtttg attccattga tgactttatt aggaccgtta
     3181 gctgtagcat tgatgaccgg atcactggtg gtagaaaata tctttgctat tcctggtatc
     3241 ggggaacaat tcgttaagtc aatcacaaca aatgattatc ctacgatcat ggctgtaacg
     3301 atcctttact catttatgct gatttttgtt attttgatcg tggatctatt gtacggtcta
     3361 gttgatccaa gaattcgtgt ttcagaaggg agccgaggat aaatggaaat gataccaaag
     3421 cgttatgaaa cagttgcaga tatccctgcg gatgaatttc ttccattaca aaaaaatacc
     3481 gaagaagaac gtgaacagat tactgcacct tctttgaatt ttatccaaga ttcatggcgc
     3541 cgtttaaaga aaaacaaagc tgccgttatt tcaatggttt tactattggt catcattttg
     3601 atctctgtga tcacaatctt tgtttctcct catgatccaa ctgcccaaaa cgtggcttat
     3661 atcaatttgc ctcctcgtat tccgggaatc aatatcgatg gattgaatgg aaaagcaatg
     3721 gttggtggtg aacttgttga taaatatgct caagcaaacg tcccttcaaa cgtaaatttc
     3781 tttttaggaa cagacggttt gggacgtgat gtattaagcc gcttatttat gggaatgaga
     3841 atctcgttgc tgatcgcatt tattgctgca ttactagatg taacgattgg tgtagcttac
     3901 gggttggttt ctggtttgtt aggcggacgt gtcgataacg tgatgcaacg ttttttggaa
     3961 atcttatcag gaattccaaa cctcgttgtc atgattttga tgttggtcgt ttttgaacca
     4021 ggaatttttt caatcgtggc tgctatggcc atcacaaact ggataccaat ggcacgtatc
     4081 gttcgtgcac aaacaatgaa attaaaagat caagaatatg ttttagctgg attgacatta
     4141 ggtgaatcaa gaatgaaaat tgcattcaaa catattttgc cgaatatctc tagtgtcatt
     4201 attattcaaa tgatgtttag tattccatct gctattttct tcgaagcctt tttaagcttt
     4261 atcggtttag gtcttacgcc tccgtcagct tcattaggaa cgatgttgag cgaagggtac
     4321 aagacattcc tgtatctgcc ttatctatta tggattccgg cagtaacttt atcggttatc
     4381 atgattggct ttaacttact tgctgatgga ttgcgtgatg cctttgatcc taaaatgaaa
     4441 gagtgaagac gatgacgaaa attttagaag tgaaagactt agaaatctct tttgatacgt
     4501 atgctggaaa ggtacgagcg attcgcggtg tcaattttca tttgaataaa ggagaaacat
     4561 tggcgatcgt tggggaatct ggaagtggaa aatcagtgac gaccagaagc atcatgcgct
     4621 tgctgtcaag caacgccaat atagatgctg gtcaaatcct ctttaaaggt aacgatatcg
     4681 ttggaaaatc agaaagagag atgcaaaaaa tccgtggtaa agaaatagcg atgattttcc
     4741 aagatccaat gacctcttta gatccgacga tgcccattgg gaagcaagtc gctgagtccc
     4801 ttagaaagca taataaagtt tcaaaaaaag agggacaaaa agctgcatta gaattgctta
     4861 aattagttgg aatacccgaa gctgagaaac gtatcaacag ttatccgcat cagttctcag
     4921 gaggtcagcg tcaacggatc gtgatcgcga ttgcactggt atgttatccg gaaatcctga
     4981 ttgctgatga acctacaaca gcgcttgatg tgactattca agcacagatt ttggagctgc
     5041 tgaaagaaat tcagacaaaa atcgatacat caattatctt tatcactcat gaccttggtg
     5101 tagtagcgaa tgtcgctgat cgtgtcgctg tcatgtatgg aggaagaatc gttgaagttg
     5161 gaacatcgga agaaattttc tacaacccgc aacatcccta tacttgggga ctgcttggtt
     5221 caatgccgac attagatagt gcgaacgatc gattgtatgc tattcctggt tctccaccgg
     5281 atttattgaa cccgccaaaa ggagacgcat tctatccaag aaatgaattc gcgatgaaaa
     5341 tcgatgcaga acaagaacca ccattttttg aactatcaaa aacacacaag gcagcaactt
     5401 ggctacttgc tccgcaggca cccaaagtga caccgccaga agaaatccaa cgtcgctggg
     5461 ctatctttaa agagaaacaa aaacatactt acggtcaagg aggaattgct gatgccaaat
     5521 aaactacttg aagttaaagg attgaaacag tatttcaatg taggaaaaaa gaatgaagta
     5581 catgctgtaa atgacatcag ctttcacatt tatgaaggag aaacattcgg tttagttgga
     5641 gaatctggaa gcggaaaatc cactactggc cgtacgatca ttcgcttgaa tgaacctact
     5701 gatggtgaga tattattcga cggtcaagat ataacgaaga tcaaagataa aaaaggtttg
     5761 acgaaattcc ggcatgatgt tcagatgatc tttcaagatc catacgcttc gttgaatcct
     5821 cgtatgaaag tcagagatat cattgccgaa ggaattgatg ttaatggact agctaaatca
     5881 tctgaagagc gtgcaaaaaa agtcgatgat ctattgagaa ctgttggatt gaatccaagc
     5941 cacggtactc gttatcctca tgaattttca ggtgggcaac gccagcgtat tggtattgca
     6001 cgagcattgg cagtaaaacc gcgttttatc atttgtgatg aaccaatttc tgcactagat
     6061 gtgtcgatcc aagcccaagt ggtcaatttg ttgcaagatc tccaaaaaga acatcaattg
     6121 acctatctat ttattgcaca tgatttgtcg atggttaaac atattagtga ccgaatcggt
     6181 gtaatgcata acggcttgtt attagagatg ggaacaagtg atgaaatcta taatcacggt
     6241 gttcatcctt atacagaaag tttgttatct gctattcctc taccagatcc agaccatgag
     6301 agaaaacgca gaagaatcaa atatcaacct gaaccagatg acggacaagt acgtcaactt
     6361 cgtgaaatcg caccagaaca ttttgtctat gcaactgagc aggaagtccc atattacgca
     6421 aaaaaactaa aacgacaaaa ggaatctctt ctggttgcta actaggaggg acatagatgc
     6481 taaaagcttt taaattccgt atgtatccga cagaagaaca aaaacagcaa ttgattcgta
     6541 cttttggatg tgctcgattt acctataacc atttgctgaa aaagcggcag aaaagttggc
     6601 aacaaacagg agtagccaat ttttcgctca cacccgctac attaaaaaaa gaatacccat
     6661 tcttaaaaga agtagacagt cttgctttag caaatgcaca gcttaatttg gatcgggctt
     6721 ttcgcaatta tttcaaggga cgtgccagct tcccaaagct taaaacgaaa aaaagtatgt
     6781 ggcaatctta tacgaccaac aaccaaaccc gtacgatcta tctggaaaat ggctacttaa
     6841 agttaccaaa acaaaaagaa ctaatcaaga taaatcagca tcggccagtt gaaggatcga
     6901 ttcgctccgc tacgatttct gctcgatata atgaagaatt ttatgtcgca ctactttgtg
     6961 atgtttcgcc agtaaaaaaa gaatctttag ctaaatggat cgggatcgcc tatcatccga
     7021 agacattgat ccaaacatct cgacctctag aagtaacttt accaaaattt caccagacag
     7081 aagaaaagct gcaacatgca cagcggaaat tgaatgtgaa agtccgctcc gctcaccata
     7141 gaaagatcag gttagatcag gcaagcaatt atcagaaaca aaagagaaaa gtaatggatc
     7201 tttatctgaa acaaaagaac cagcgagaag attatcttga acaattatct gggaaattgg
     7261 tcaaacaata tgactactta tttgtagaat cttttccaaa agaagaggca catgctgatt
     7321 tttctattca cgactggcat aaattaataa caaaattgcg ttataagtcc caatggtata
     7381 ataaaaaatt tcttttgatc aataccgacg gagcagaaga aagcaattcc gtaagaaaga
     7441 gccaagtagt agaaaaaatg ggcagacatt cggttatcaa gggataaaaa atgaatgaaa
     7501 ctgataggag cgttagggtt agccttgtta ataaaaagtc ttaatgactt ttgtttctag
     7561 gaatttttct tttgaagaaa agctcactaa ttatgacaaa ccaataaaac aatagcagaa
     7621 aaagttcgta cgagcttttt ctgctattgt taatttttta ttcagaaagt ttacgaatac
     7681 atcaaaattc tgaaacaaaa aacgtaactc acaaagagtt gtttttgcgt tttttcttga
     7741 atgattaggt ctgaatcttt tgctcacaac cttattcatg gtgccccggc ttgagctgat
     7801 agatttttga aggacggccg attcctacag gacgttcacc gatctcatcg aaatattgga
     7861 gcatagcttt cttaaaattg gaatgatcga tcgttttata atcgatccct aagaatttag
     7921 caaatacttt tcgagcttcc gtaatcgtga aatctttacc taaaacttgt agaacttgcg
     7981 gctcgtgttc cattttattg actacacggt tgaatgcttt caagatgatt tgactatggt
     8041 caaaagccaa agtatctttg ccagaagact ctccagtgac taaatcaagc gagatagcca
     8101 cttctccgct agataaatgg atcttgttac tatgacgttc tagtgtgaac cagcgtactt
     8161 ccttggcatc atctccggcg attagcggtt cttctccaat aaaggctaag tagctgactg
     8221 tgacgaccca gcctcgcgga tctcgattag gcgtactgaa tgtatgcagt tgctcaatat
     8281 tttcttttga aataaccaca ccagtttctt cctttgtttc tcttaagacg ctttctccag
     8341 ttgactcatc cttttggaca aagccaccag gcaatgccca tgaatttcga taaggatgcc
     8401 cttttctttg gatcaacaaa actttcagct gatcttcttc tttgttatag cacatcagta
     8461 cgatatcgac agtcaaagag ggcttgtcat attctggacg ttcctgtttt tgataccagt
     8521 taagaaattc ttcttcactt gctttatgtt cataatataa tttttcttct tctttagaag
     8581 caaaacggtt catctgacca cctccattga cagtaaaagt actttttacc ttattgtagc
     8641 agactctgaa aaaaaaccaa ggatttactt gaaaaatcta ggttatcatt taaatatgaa
     8701 aaataaatgg aagtatgaga ttgaataaaa agaaaagcag ataaaacggc aatactttat
     8761 accgctcttc acgaatggca aagaagccac aaataacgat atatacgtca atgataaaac
     8821 gcaaaatcca agctgctgtc ataaaactgt tcaaatgccc atggaggtta aaataaccat
     8881 acatacgaat ataaaaatag ctgaatatta aatgtgctaa tgaaagaaaa gcaatactaa
     8941 gtgtaaaaaa aagatgtttc ttctgcatga ttgttccagt cccttactaa gatagatagt
     9001 ctttattata ccacgtgtga ggggagaaat aaaaagccgt tttttagtag atatgaaaca
     9061 aaacaaaaac ccgcatttat tcaacctatt catcctttta aaggatagat tgaacgtaga
     9121 tagaagtcgt ttatccagtc tttttcattt tgaaaaaaag ctaacagcat gcttttttta
     9181 tggtatacta gcaaggaaac gaattcgcat catgcgataa aggaggaaga gccccgtggc
     9241 agaaaaggaa actttttata tcactacgcc aatctattat ccaagcggca aacttcatat
     9301 cggcaactcg tatactacga ttgcatgtga cgcaattgct cgttataaac ggttgatggg
     9361 ctttgatgtg ttttatctca ctggagtgga tgaacatggt caaaaaatcg aaacaaaagc
     9421 agaagaacta ggtgtaaaac cgcaagaata tgtagataaa atggcggctg atgtcaagaa
     9481 attatggaaa acgcttgata tcagttatga taaattcatt cgcacgacag atgattacca
     9541 taaagcagct gttcaaaaaa tatttgatcg tttattagaa cagggagata tttacttagg
     9601 tgaatatgaa ggctggtact ctgtttctga cgaagaattc tttacagaaa cacaacttgc
     9661 agaagtgtac aaagatgacg aaggtaacgt gatcggtggt aaagcgccaa gtggacacga
     9721 agtagaattg gtaaaagaag aatcatactt cttccgcatg agcaaatacg cagaccgtct
     9781 attggaatac tatgaagaac atcccgaatt catccagcca gaatctcgta aaaacgaaat
     9841 gatcaacaac tttatcaaac caggattaga ggatcttgca gtttcacgaa caacttttac
     9901 ttggggagta ccagtcaaga gtgatccgaa acatgtggtg tatgtatgga tcgatgcatt
     9961 atccaattat attactgcac taggatatgg ctccgaagat gaaagtctat tcgaaaaata
    10021 ctggcctgca gatgttcaga tggtcggtaa agaaatcgtt cgctttcata cgatctattg
    10081 gccaatcatg ctgatggccc ttgatttgcc tctacctaaa aaagtatttg ggcatggctg
    10141 gctattgatg aaagacggaa aaatgtctaa atcaaaagga aatgtcgttt atcctgaaat
    10201 gcttgtggaa cgttatggtt tagatgcact ccgttattat ttgcttcgtg ctgttccgtt
    10261 tgggtcagat ggtgtcttta cgccagaaga ttttgtttcc cgtgtcaatt atgatctggc
    10321 aaatgatcta gggaacttat tgaatcgaac gattgctatg atcaacaaat attgtgatgg
    10381 actcgttcct gactatgcct cacttgtcac tccatttgat agtgaactgt ctacgacggc
    10441 tgctaacgtt gtcggacgtt accatgatgc aatggaaaaa atggaattca atacagcatt
    10501 ggctgaaatc tgggtgctga tttctcgtgc aaacaaatac attgatgaaa cagaaccatg
    10561 ggtattagca aaagacgaag aaaagaaagc tgaattgaat agtgtcatga tccatttagc
    10621 tgaatctttg cgtatcgcag cgatattact tcagccaatc atgacagaaa cgccagagaa
    10681 gatcttcaat caactaggat tggactctga aacaatgaat cttgaaggat tacactttgg
    10741 cgaatttcct tcaggaacaa aagtagttgc aaaaggtaca ccaatcttcc cacgtttaga
    10801 tatggaagaa gaagttgctt ttattcaaga aaaaatgtct gaaggtactc aaacaaacga
    10861 agatacagtc aaatgggatc cagaagaaac agaacttgtt tcaacgaaag aaaaacaaat
    10921 caaatttgat gtatttgaaa aagtagaact aaaagtagca gaagtcatca actgtcaaaa
    10981 agtagaaggg gcagataagt tgctgcaatt ccgactagat gctggagaca gccaagaccg
    11041 tcaaatcttg tcaggaatcg ctgaatttta tcctgatcca agcgaattga tcgggaaaaa
    11101 agtcgtcatt gtagcaaatc tgaaaccacg aaagatgcgt ggacaaatca gtcaaggaat
    11161 gatcctttct gcagaagcac cagatggctc tttacaagta atcgaagcac caaaatccat
    11221 gccaaatggc tcagaaatcg catagaaatt caaagggggt atgacactag ttgtgtcata
    11281 cccccttttt ccgaaatttg agaagcaatt ttcgtaaatt ccttcttatt acttgaagcc
    11341 aatcatataa tacagaaaca gagaactatc caaaataaat cctagaaaaa gaagtacgag
    11401 cttcgctgat ttttgttaat ttagaataat actaatagga atcgtaaaaa cagaaaaaaa
    11461 gcataatgat aaagggtcgg gcagatttta attgattcat ctggtactct tttttattgt
    11521 ccttacattc ataaagtttg aatgcaatga ctttattaca tctatattta tatctaacag
    11581 tagcgttgat gtgttaatta taagttctat cactttatgt tcaattagtt tgtgctctta
    11641 tatgtgtgat tgaaaatata gataaaaaaa caatcatcgg ctttgacttc gatgattgtt
    11701 ttctttattt tgtaaaaatc ctatcacttg attttatggt aaccttttat ttttgtcttc
    11761 aaacggcttg gtaagagagc agtaagcagt gcaaatggga tcgaaaagac ataccagaaa
    11821 atcgtacgtc cgataccata atgttgatag agctttgtca acatcacgtg taacaagatc
    11881 aaccctaaaa gcaaggagcc agctataaac caatgattat cccaatgcat gacttcacta
    11941 agtgccatca ctccaaaagg atagaaataa aaatagatcc cgactaaggt catccgccag
    12001 ttctttgtaa atgttccgat attcaataaa aagaaaatcg ctgaaagcaa aataccgata
    12061 ggcggaaaaa gcccaaccaa aaaggaatac aacatccccc acaagatcat cacaggacct
    12121 ttgatcaatg caacgattgc gatgaacaaa gtcagcaata ttagtttttg tgataacgtt
    12181 gcaacagtca ttaatccaaa taaaattaat gtgaaccaat gccaatggga ctgctgttgt
    12241 tctttacggg aaaaatcgac ccggttggat aaataatctg ctaatttcgg ataagaacgc
    12301 ttaaaatcca taaactgttc ctccttcgtg gaaaaggtag gtttagtata cgaaaaataa
    12361 aaaagaaata catccgtctt aagagggagt ttttcactga aagtggagaa aaaagaatgg
    12421 taaattaaaa tattctcagt tatactgaaa attataccaa atttcaaaga agaaagagga
    12481 tgggaatgaa aggcaaacta aaacgagaaa tcaatctgtt tggcgcatta gctaccgtta
    12541 tgggaaccgt gatcggtgca ggcgtcttct tcaaaactgc tgctgttact gctagtactc
    12601 agtctacaag tttgacattg ctagcttggc ttttgggtgg tttcttaacg atctgtgctg
    12661 gattgacagt ggctgaatta gctacagcaa tcccggaaac tggtggagct gtaaaatata
    12721 ttgaagctgc gtatggaaaa ttgcccagct ttttattagg atgggcgcaa agcttgattt
    12781 actttcctgc taatattgct gcattatcga ttatctttgc gacacaattg acgaacttat
    12841 tacaattatc taccgattat cttttgttga ttgcagtgat caccgctgtt tctgtgacag
    12901 ggttgaattt gttagggaca aaagtcggtg cttctgtaca atcagtgacg ttgattgtta
    12961 aattaatacc aattgctgtg attgtcatat ggggattatt gaccccagga caaggaactg
    13021 tccagttatt tccaatcgaa gctggaaaag atgttacttt tgtcgaagga ttgagcagtg
    13081 cgttgttagc aacgttgttt gcttatgacg gctggttagg tgtcggtgca atggcagggg
    13141 aaatgaaacg gccggaaaaa gatttgccta aagcaattat tcttggtttg agttttgtaa
    13201 cagtcgttta tctattgatc aattttgttt ttttgaaaac tttgccgatt gatcatcttg
    13261 ccggtaattt gaatgcagct tctgaagcat cagacgtcat ttttggagga atcggtggaa
    13321 agctggtcac tattgggatc ttgatctcgg tatacggtgc attgaacggt tatacactaa
    13381 ctgggatccg cgtgccttat gcgatggctt tagaagacga gctacctttc agtaaacagc
    13441 tgacaaagct ttcaaagaag tttacggttc cttatgttcc tgcggttttc cagttagcag
    13501 tagcttgtat tatgatgagc cttggttctt tcgacttttt aacagacatg ttgatttttg
    13561 tgatgtggct attcagttta ctgattttta tcggtgtctt tattttaaga aaaaaagcgc
    13621 cggaattgcc acgtccatat aaagtaccac tttatccaat cgttccgatt attgcgattc
    13681 tcggtgctat tttcatttta ggtatgacga tgatgacgca aacgaaatta gcattgatcg
    13741 gtataggtgt taccttgata ggtatcccag tctattatca aaaaaagaaa aaacgctcag
    13801 aagagtaaaa tatttcaaca acagacagaa aaagtacgaa ctaggtcctc tagatcttcg
    13861 tgctttttct atttcaataa aacaagttct tctattttga tttttgctac ttctgcaagt
    13921 agtgcttatg tgctaaagta agaatgaaaa ggagagataa acatgatatt tgattctcat
    13981 acccatttaa atgctgaaca gttcaatgaa gatattccag aaacgattca gcgagcacaa
    14041 gaaatggggg taacgaaaat ggcggtcgtg ggcttcgata cgccaacgat tgaaaagtct
    14101 ttgcaattaa gccatgacta tccaaatata tacagtatta tcggctggca tccgacagag
    14161 gctggcagtt atacgaaaga aatcgaaaat aaattacaag aacaattgac tttaccaaag
    14221 gttgtagcat taggggaaat tggcttggat tatcattgga tggaagaccc gaaagaagtc
    14281 caagataaag tatttcgcag acagattgct atcgcaaaag aaatgaacct accaatcagt
    14341 attcatacta gagaagcact tgaagacacg tatcaaatcc taaaagaaga agatgttcga
    14401 gatatcggtg gaatcatgca tagtttcagt ggtgattatg aatgggcaaa acgatttctt
    14461 gacttaggga tgcatatttc atttagcggt gtcgtcactt tcaaaaaagc attagacgtc
    14521 caagaggctg cagcaaatgt accaatcgaa cgattacttg tggaaacaga tgccccttat
    14581 ctggcaccag ttccttttag aggaaagcga aatgaaccag gctatactcg ttatacagta
    14641 gaaaagattg ctgaacttcg gaatcttccg acagaagaag tggctgccca aacatggaca
    14701 aatgcgcacc gattatttgg tctaagcgaa catggataag atgaagatcc aagagattat
    14761 agtcgttgaa ggaaaagacg atacaagaag gctgcgggaa gtagttgatg cagatacgat
    14821 agaaacaata gggtctgcaa tcaatgaaga gatcctgatg caaattgaac atgcccaaga
    14881 gactcgtgga gtgatcgttt ttaccgatcc tgatttttca ggagaaaaaa taagaaaaat
    14941 cattatggaa gctgttcctc aggcaaaaca tgcttttttg ccgcgcacac aagctaaacc
    15001 aaagaaaaag ggaagccttg gtgtcgagca tgcaagtgat gctgctattt tagaagcatt
    15061 gaaaaaggtc gtgacgccag acatttccca aacggctgtt tctgaaatca ctagacaaga
    15121 ccttttagac tatggtttaa tagctggggc acaagcaaaa gaaaaacgag aaaaactagg
    15181 tgacgagttg cgcatcggtt acacgaacgg caaacaattg gaaaaacgtt tgaagatgtt
    15241 tcgtattacg ccgaaagaac tcgcccaagc aatgaaaata gtggaggaac aacatgagtg
    15301 aatatcgtga aattgcgaca ccctctagaa caaaagagat tttattgaaa catggttttt
    15361 catttaaaaa aagtttagga caaaattttc tgactgaacc aaatatttta aggaaaatcg
    15421 tagaaactgc gcaaatagat gaacatacga acgtgatcga agttggacca ggaatcggtg
    15481 cattgacgga acaattagcc aagcatgcaa aacaagtcgt agcatttgag atcgatgatc
    15541 gtttgatccc tgtattggct gatacgatgc aaccctatga caatgtgact attgtacatc
    15601 aagatatttt aaagaccgat ttgtcaacag ctgttagaga aacatttcat gaggagcttc
    15661 cgttaaaagt cgtagcgaat ttaccttact atattacgac accgatcatg atgcattttc
    15721 ttgaatcaga tttggttgtg gatgaactag tcgtcatgat gcaaaaagaa gtagctgatc
    15781 gtatctctgc tgaaccagga acgaaagctt atggttcatt atcgattgct gttcaatatt
    15841 atatggaagc cagtttagca ttcatcgtac caaaaacagt atttgtccct cagccaaatg
    15901 tagattcagc gattttgaaa ctgacaagaa gagatatacc ggcagtcgaa gtgacagacg
    15961 aaaaagcatt tttccgattg acaaaagcgg catttcagca aagaagaaaa acgctttgga
    16021 ataacttgca gcattcgtat ggcaaagatg accagacaaa agcatggtta gcaaaaagct
    16081 tggaaacagc tggaatcgat ccaaaacgtc gtggggagac tttgtcatta caagaattcg
    16141 ccgcattaag caatgcgatg tcagaaaata tgcagtaaaa aaagaggttg tgacagaagt
    16201 tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca aacaaaaata gttcctcatg
    16261 tttttcgttt gtttgggctt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    16321 aggttgtggg cctgccgttt aactctaagt cacaaggaac aatttcaaaa aacagcttct
    16381 catgtttttg agttagttgg tcttattact tgatgcaagc ttttgaccac tattatgccg
    16441 aacaaggaga tgtgacacaa attttgtcac atctcctatt tttgtttctt gatcaaaaaa
    16501 ttcttatact tgatactcac actcattttg tatggattta gaaaagaata tgtgtcttga
    16561 cagttattag taagtgagtt atactaagtc gacatttatg tgtcaagaca tattaggaga
    16621 gagaaaaaat gagaaaaaat tcagttcgaa aactaacgat ttctgcttta ttgattggga
    16681 tgggggtcat tatcccaatg gtcatgccta aaatcatgat tccaccagct tcctttactt
    16741 tggcgtctca tgtgccatta tttattgcga tgttttttac accaggagtt gcagtggctg
    16801 ttgcgctagg tacgacattt ggtttctttt taacaacgcc ggttatcatc gcattgcgag
    16861 cattgtcaca tcttgtgttt gcgttgattg gggcttggta cttgcaaaag catccgagta
    16921 tcgttttaaa aaatggacag tttacttttg ctaattggcg tttccaaggg ttcaattttg
    16981 tgatcggtgt gattcattct ttagcagaaa tgctagtagt cagcatcttt tactttattg
    17041 gtaatatgcc tgaaacatat tattctcaag gatattttta tacagtattc atcttgatgg
    17101 ggattggtgg gcttatccac agtttagttg attataatat tgcttatttt atagcaggaa
    17161 cactcagcaa atattttgat atccccgtat ttacggcagc aaaaaaagaa aatcggaaag
    17221 agtcgattca agggtacgcg aagaaaacga catattagac atgatctctc aaaaaaaaaa
    17281 ctctcatcta gtaatggata ataaatcctc taagatgaga gttttttgtc ctaaaaagag
    17341 ctgcaccaac atcttctggc acagctctaa cagggggcaa tttatggaag tttgatgact
    17401 tgttctgttt ctttatcaaa gaagtggcct ttgctgatgt tgaaggcaag gtcgactatt
    17461 tcgcctggtt tatggaaatc tcttgcatct acttttgaga tgaactcagt agaaccagtt
    17521 tttgtgtaaa gcatcgtttc agctccaagt aattcggaaa cgacaacttc tgatttcact
    17581 acggcttcag gtgaagcttc aagggctact tgttcactgt ggatgtcttc tggacgaata
    17641 ccgaagataa cttcttttcc ttcataacct ttttcaacta atactttgtt ttttccttca
    17701 ggaatacgaa gcttaagccc atgtccatct gtgataacac catttttcaa tgtcacatta
    17761 aagaagttca tggcaggaga tccaataaag ccggcaacga acatattgac gggtgtatca
    17821 taaacttctt tcggtgtacc gatttgttgg ataaatccgt ctttcatgat aacgattcgg
    17881 tcagccatag tcattgcttc tgtctgatcg tgagtaacat agatggtcgt tgtttcaaga
    17941 cgctggtgaa gtttggcaat ctcagcacgc atggctacac gtaatttagc atctaaattt
    18001 gataatggct catccattaa gaagactttt gcatcccgaa cgattgcccg tcccaatgcc
    18061 acacgttggc gttgtccacc agataaagca gctggttttc gtttcaagta ttctgtcaga
    18121 cctaagatct ctgctgcatt gtccacacgt tttttgatgt ctgctttatc atatttacgt
    18181 aatttcaagc caaaagccat attatcaaaa acagtcatat gaggatacaa tgcgtagttt
    18241 tggaaaacca tggcaatatc acggtcttta ggtgccacgt cattcatgac ttttccgccg
    18301 atatttagtt ctccttcaga gatatcttcc agtcccgcga tcattcgcaa agtagttgac
    18361 tttccacaac cggaaggacc aacaaaaacg ataaattcac ggtctttgat tgatagatta
    18421 aaatcagtta cagaataatt ttctgcattg tcatattttt tatatacgtt tttcagagcc
    18481 atttctacca taatacgttc cacactttct tttttagttt tattaactat ttaaagtata
    18541 aatgaaagcg ttaactaact tcaatgtcat gttgaacaag aattttttct tttttttgtc
    18601 aatgtgctag ttttaagctt taataaatat ccataagaaa taaaaactga tacactggag
    18661 taaataagta tgttaacaat atcaaaagga gtgtctctta tgaaaatcgc tttgatcgct
    18721 catgaccgaa aaaaacctat gatggtgaaa ttagcaacag cgtataaaac aatattggaa
    18781 aaacatgaac tttttgctac cgggacgact gggcagagga tcacggaagc aaccggcttg
    18841 ccgatccatc ggtttaaatc cggaccgtta ggcggggatc agcaaattgg agccatgatt
    18901 tcggaggatc agttagattt ggtgattttt cttcgagacc cgctggctgc acagccccat
    18961 gaaccagatg taacagcact tatccgttta tctgatgtct atgagattcc gttagctacg
    19021 aatatcggaa cagctgaggt gctactaaga ggactggaag ccggcttcct agattttcga
    19081 agaatcgtcc atgaaataga caagcatcca ctttcatttt gatggataag cgtatggaaa
    19141 aataacgttt aatgttcgcc tatatgtagc tataaaagct aaacaaactg ataatatgcg
    19201 atataatacg aacgtattgg ataatataaa caataatatt agtttttcgt atttgcagta
    19261 aatgtgaaaa tatgctatag tttctgtggg aaaagatccc aaaaataata cagagtagaa
    19321 aataaagcgt taagtgctaa gaggatggga tgttgcctct tggacgaagg acgtaatgtt
    19381 cgcggtttta ttttcgcatt cgctgcatga tacgatgtag cagctcttaa aggagatgct
    19441 aaaaatgaag aaacaccggt tagacgcacg tatgattgct attatgggct tattgattgc
    19501 attgatggtc actttgtccc gactggtagc aatcgagacc ccatttatta aaatcagtgt
    19561 cacatttatt ccacaagtga tcatgggcat tctttttggt cctttttggt cagggatagg
    19621 cgcagtttta gctgatttag taggaatggc cctcttctcg aaatctgcat tctttattgg
    19681 atttacattg aatgcattta ttgaaggagc aatctacgga ttctttttct atcgaaaaga
    19741 gatcacttgg aaaaatgcca ttctggctac gcttagtgtc acgctgatca tcaacttatt
    19801 tttgacacca ttatggcttg cgttgatgta ccatgtgcca ttgttcagct gggtcgtttg
    19861 ggcgccccgc ctgttaaaaa cagtaatatg gttaccgatt caatcaattg ccatttatta
    19921 cgtaggacgt agtattcctt acaaaaaaat tttaagaagt ttagcgatcc acgctaaata
    19981 aaaaacaagc agtcttccca tcccagaaga ctgcttgttt ttattgtgct gtgaattgtg
    20041 cttgatagag ccgtcggtaa taaccatctt tttgaagcag ctcatcatgg gtgcccattt
    20101 cgacaatagc tccctgatcc atcactaata tctggtccgc atttttgatt gtggacaggc
    20161 gatgggcaat cacaaaactg gtttttcctt ccatcattgc taagaaggct tgttggattt
    20221 ttttctctgt caatgtatcg actgagctgg tagcttcatc taagatcaac atagggggat
    20281 tactgatcat cgttcgagca atcgtcaaca gttggcgttg tccatctgat atctttaacc
    20341 cttgaccgcc aatcttagta tctaattttt ccggcaaacg ttctacaaat tcatacatat
    20401 aagaggcttt tagggcatca ttgatttctg cgtcacttgc ttccggattc ccaaaacgaa
    20461 gattttctcg caatgtactg tcaaatagcc aagtatcttg taacaccatt ccaaaacttt
    20521 tacgtaatgt atcacgttgg atagagcgga tgtcatggtc atcgactgta attgttcctt
    20581 ttgttgtgtc ataaaaacgc atcagcaaat taacaagtgt ggattttccg gcccctgttt
    20641 ttcctactat agcaatggtt tgacctggat aagcagtaaa attgaaatct tcgatcaaac
    20701 gctgcttggg gtcataagaa aaagaaacat gatcaaaaga gacttttcct ttgatatttt
    20761 tgggttccaa ggcataggca tctggcaaat caggcttttc ttctggctga tcgatcaaat
    20821 caaatgctcg ttctagacca gaaaaagcgg tttgcagttg tgtcgtgatt ccagaaagtt
    20881 cgataaatgg tttagaaaac tgacttgagt agatcgtaaa gctggaaatc acaccaacag
    20941 tgattgacga accactcttc aatgccaata ggccgccaac taaaccaatc gataaataag
    21001 caaggtgatc tacaaaacga gaagacgggt ttgtcaagga agaagaaaat tgtgcccgtt
    21061 gtcctttttc atatagatca gcatttagca gttcaaattg ctgttgacta gcttcttctt
    21121 gctgaaaagc tttcacgatt ttctggttac cgattcgttc ggtcacaaag cccgagatat
    21181 ccccaataat cctttgctgt ctatcgaaat ttgtttgtga agcacgagca acgatccaac
    21241 tcacaaggaa aataattggt gtagaacaaa gaacgaccaa tgtcagaagt ggacttagac
    21301 gcatcataaa aataaacgaa agaatgatga ttgccactcc agaaaataat tgattgaagg
    21361 ccgcagaaat tgcaatggaa atattgtcca tatcatttgt aaatcgactg acgatatttc
    21421 cgtgggagtt ttgatcataa taacgaagtg gcaatcgatt cagatgagca aatgcatctt
    21481 ttcttaattt tgcaacggat aagtaagcta accgattgct taacacttgg atgagccatt
    21541 gactgactac gttgattaaa acgataccac cgaatagaat aagtaaatgg aacagtcgat
    21601 tgaagcggac ctgtccttct ccaatcattt gatcgatact ttgaccaatt tgtaacgtca
    21661 tcacaactgt tgcaatccca ttgatgattc ctagtatcac agctagccaa atgtcttttg
    21721 cataggcagt aaggtaagga atgaatcggc ggagcgtctg caaggataat ttttttactt
    21781 tcataactat tcttcctcct gtgatgcgac gatttcctga tattctgctg attgagcaag
    21841 taattcttca tgggtaccct gagcagcaat cttaccttga tccatcacta agatatgatg
    21901 tgcttcttga atagagcgga cacgttggga gataataatc actgtactgc caagataagt
    21961 ctgtagcgcc ttacgcaaat ccaagtctgt ttgataatcc aacgcactta aagagtcatc
    22021 taaaatcagt aatgctggct tggcaatcaa agctcttgca atcgtcagtc gctgtttttg
    22081 tccgccagag aaatttttcc cattttccat gacttttgta tctaaaccat ttggaagctg
    22141 acggacaaat tcttctgcct gagcgatttt cagagcttcc caacattctt tttctgtggc
    22201 gtctttctta ccccattgaa ggttttcacg aatagtcccg gtaaatagta cagaagtttg
    22261 gggaacaaga gcaatttgct gacggagatg atccagctgc caagaacgaa catccattcc
    22321 gtccattata actgtaccgg aactgacatc atagaaacgc ggaatcaatt gtgtcaaagt
    22381 cgttttcccg cttccggttg gaccaatgat tccaaggact gtatttcgct tcagctgaaa
    22441 tgtaatattt tggagagaaa gaccagaatc aggagtataa cggaagtcaa catggtcaaa
    22501 agcgataatt gcttcagaag aaaaatcggg agtagtactg acctcagctt caagaatcga
    22561 attttctgtg tctagcacct ctttcacccg atttcctgaa gcttcggcac gtgtgaagat
    22621 cacgacgagg tttgaaacaa cgatcagtgc caaaagcatt tgattcatat aattgatcaa
    22681 agcaagaact tgtccttgtt gcaagctacc aatatttact ttgatcccgc caactgtcag
    22741 caaacagatg atcccgacat tcatgatcaa ggttgtagca ggtgataata gggcagagat
    22801 attggaaaca cgtaaataat tgttcgctag atcatttgtg cttttatcga acttctctgt
    22861 ttcttttttt gtctgcgcaa atgcgcggat gacacgaaca ccgctaagat tctgactaac
    22921 gtgttcattg agctgatcta gtttttcttg cactttttgg tagagaggaa cggttttttt
    22981 gatgataaaa aataaaatga ttgagaaaat aggcaataat gctaagaaaa acagacctac
    23041 ttcccagtcg atcacaaaag ccatgaccac tgacccgata cttaaaaacg gtgctctgat
    23101 caataaacga atgaccattg ctaaagctag ctgaagctga ttgatgtcgt ttgtcattcg
    23161 ggtgatcaag gtatctgttc caaaatgatt caactcgttg tgagagaaag tattgatttt
    23221 tttgattagc tgattacgta actctgtacc aaatccttgt gaagctactg aagcatagta
    23281 ttggcaaatg atagcacaaa tcagaccaat cacagacata gcgaccatcc ataagcccat
    23341 ttcaatgatt tttcctcggt cattcatttt tagtccatta tcgatcaagg aagccatcat
    23401 taaaggcagg acaagttcga agacagcttc aagaaatttg aagaacgggc ccaaaatgat
    23461 ttgcttacga tagtcttttg cataacgtaa taactgaatc atatgattcc tcctattatt
    23521 tatttgtcca caattgaaaa aacaagtact accacattgt agcttaggaa atttagaatg
    23581 aaaagagaac aagccttttc ataaatgaaa gttttattat gaagaagctt tagaaattga
    23641 atagactatt ttttttaaaa aaaagaaaat gagaaaacat gccagtctct tcattcatag
    23701 gaacgtctat tttacttaat ttttctataa atgaattctg
//
LOCUS       DACDAF010000041        23673 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.041, whole genome shotgun sequence.
ACCESSION   DACDAF010000041 DACDAF010000000
VERSION     DACDAF010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23673
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.041"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            118..1545
                     /locus_tag="IVZ69_001486"
     CDS             118..1545
                     /locus_tag="IVZ69_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP8183576.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1637..2002)
                     /locus_tag="IVZ69_001487"
     CDS             complement(1637..2002)
                     /locus_tag="IVZ69_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP8183577.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1999..2364)
                     /locus_tag="IVZ69_001488"
     CDS             complement(1999..2364)
                     /locus_tag="IVZ69_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HAP8183578.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2556..2804)
                     /locus_tag="IVZ69_001489"
     CDS             complement(2556..2804)
                     /locus_tag="IVZ69_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183579.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2803..2931
                     /locus_tag="IVZ69_001490"
     CDS             2803..2931
                     /locus_tag="IVZ69_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HAP8183580.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2988..4682
                     /locus_tag="IVZ69_001491"
     CDS             2988..4682
                     /locus_tag="IVZ69_001491"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HAP8183581.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4686..4805
                     /locus_tag="IVZ69_001492"
                     /pseudo
     CDS             4686..4805
                     /locus_tag="IVZ69_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4887..5078
                     /locus_tag="IVZ69_001493"
     CDS             4887..5078
                     /locus_tag="IVZ69_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183582.1"
                     /translation="MDLLPQMQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDL
                     LPQMQAFEHRLPRGYEKGV"
     gene            5456..6589
                     /locus_tag="IVZ69_001494"
     CDS             5456..6589
                     /locus_tag="IVZ69_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HAP8183583.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6620..6940
                     /locus_tag="IVZ69_001495"
     CDS             6620..6940
                     /locus_tag="IVZ69_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183584.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6969..7433)
                     /locus_tag="IVZ69_001496"
     CDS             complement(6969..7433)
                     /locus_tag="IVZ69_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8183585.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7564..8817)
                     /locus_tag="IVZ69_001497"
     CDS             complement(7564..8817)
                     /locus_tag="IVZ69_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8183586.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8846..9163)
                     /locus_tag="IVZ69_001498"
     CDS             complement(8846..9163)
                     /locus_tag="IVZ69_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP8183587.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9189..9509)
                     /locus_tag="IVZ69_001499"
     CDS             complement(9189..9509)
                     /locus_tag="IVZ69_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8183588.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9973..11388)
                     /locus_tag="IVZ69_001500"
     CDS             complement(9973..11388)
                     /locus_tag="IVZ69_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP8183589.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11405..12721)
                     /locus_tag="IVZ69_001501"
     CDS             complement(11405..12721)
                     /locus_tag="IVZ69_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8183590.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12871..13569)
                     /locus_tag="IVZ69_001502"
     CDS             complement(12871..13569)
                     /locus_tag="IVZ69_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HAP8183591.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(13858..14851)
                     /locus_tag="IVZ69_001503"
                     /pseudo
     CDS             complement(13858..14851)
                     /locus_tag="IVZ69_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328323.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
     gene            complement(14932..15765)
                     /gene="msrA"
                     /locus_tag="IVZ69_001504"
     CDS             complement(14932..15765)
                     /gene="msrA"
                     /locus_tag="IVZ69_001504"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP8183592.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDTRENISVKEQ
                     LSKLEVTLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQDERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(15999..16742)
                     /gene="truA"
                     /locus_tag="IVZ69_001505"
     CDS             complement(15999..16742)
                     /gene="truA"
                     /locus_tag="IVZ69_001505"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HAP8183593.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYRS"
     gene            complement(16933..17568)
                     /locus_tag="IVZ69_001506"
     CDS             complement(16933..17568)
                     /locus_tag="IVZ69_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAP8183594.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(17715..18956)
                     /gene="sstT"
                     /locus_tag="IVZ69_001507"
     CDS             complement(17715..18956)
                     /gene="sstT"
                     /locus_tag="IVZ69_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HAP8183595.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEPT
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            complement(19277..19954)
                     /locus_tag="IVZ69_001508"
     CDS             complement(19277..19954)
                     /locus_tag="IVZ69_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HAP8183596.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATIATTTTTSTESKPTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSESSEQVEQTLWNADKSAQLEAFMA
                     TWGQTMGQQYKSYTNQMSVDLYGLKVPQVILNGEWKMAIGGVPVSAEWSESGTGQADY
                     QITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELKNG
                     FNQIVYG"
     gene            complement(20205..20747)
                     /locus_tag="IVZ69_001509"
     CDS             complement(20205..20747)
                     /locus_tag="IVZ69_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP8183597.1"
                     /translation="MNIVEEKFAQETKQADIDHHKPTAGAMVGHVLANFKLEEMKLIQ
                     AQLYVLGTSSQELSTLFSEYADQEARWFNKISHELVIENEIVPSTLEEVMRYGKIYEH
                     GQNKYLPASTMLENFAKDFDFQNVFITRAIKLAEKEEKYGLKQLLVELLSFNKEIIYQ
                     VQRLQGKTVRQDLDEEDDDD"
     gene            complement(20752..20979)
                     /locus_tag="IVZ69_001510"
     CDS             complement(20752..20979)
                     /locus_tag="IVZ69_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper resistance protein CopZ"
                     /protein_id="HAP8183598.1"
                     /translation="MKKMIMQLDTLACPSCMQKIEHAVSQQPGVSNTKVLFNASKIKA
                     NFDPDEVHPEQLAAVVEKLGYEVQSTKVKEA"
     gene            complement(21058..22938)
                     /locus_tag="IVZ69_001511"
     CDS             complement(21058..22938)
                     /locus_tag="IVZ69_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP8183599.1"
                     /translation="MKLQKWIQEHRNHITALSAVLIIFGFIGKFTGFVLFYNIALAIA
                     SIIAVIPIIIHAYQAVKVKVISIDLLVTIAVLGAFMIGEYKESAIVTFLFLFGSYLEQ
                     KTLTKTRESIKALTEMAPSTASVVQEDGTTEEVEIDDVEEGDIVLVKTGGAIPVDGRV
                     IDGKGYADEAAVTGESRQVVKISGDNVFSGTILADGYVTIEATKVGDDTTFAKIIELV
                     EEAQDTKSHAEKFIDQFSQYYTPTVLLIALLVGLISRDFRLAITVLVLGCPGALVIGA
                     PVSNVAGIGNGAKRGILVKGGEAMDTFSKIDTFVFDKTGTLTKGTTAVSTIKNYTEDE
                     GDSLALVARLETLSDHPLGRAVIHYAQEKDIDFQQLAVKDNQTIKGQGITAEIDGHTV
                     CAGNTKLIAAHKLSLTPKQVQDLHQLQQRGSSVIIVAIDKKITQIIGVSDVIRPEVAE
                     QLAMLKQAGAKHLVMLTGDNQMTADYVADMLGIDEVHAELLPDEKVQFVKKYQEQGLH
                     VAFIGDGINDSPSLAAADIGIAMGSGTDVAIETSDVVLMQSSFGSLVHAYRLAKKTVL
                     NTRENVVIAIGVVLFLLIGLFAGFIYMASGMFVHEASILIVIFNAMRLLYFGHESKEE
                     KS"
     gene            23224..23559
                     /locus_tag="IVZ69_001512"
     CDS             23224..23559
                     /locus_tag="IVZ69_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8183600.1"
                     /translation="MGVEAVDKYLYLLAGNKIQKSLMDFIQELECTFHKKFTHSILLK
                     LLIHTACLIERTLINGHELKIISEDDTRPSHETIFHVKKAFKNIETEFGITVSYDECF
                     FIYDIIASK"
BASE COUNT         7348 a         4850 c         3994 g         7481 t
ORIGIN      
        1 aaaccttttt taacggcatt tatatgcttt ttcagaaatt aactgatgat ttcaaaaaga
       61 aaacatgtca taatatttcc catattgtgc aaaaaaatac aaggcggagg ctctactatg
      121 attgaagaat atattgagaa aaatatttta agacagctgt ttttatgtgg gcaattctat
      181 gtaaataaag aagtcaatct agaaaagctc tccaatctcc tgcatgtttg caaaaccact
      241 ttactcaatg atatcaataa cataaaaaaa gaatttgaag aacagatcgc ttatacacat
      301 cgggaaaagg accgttacac tttatatttt tcagaacata tacctcgatg caagatcatg
      361 cagcaattgt ctcaaaattc gttgttttta aaaacttgtc tgctttattt ggaagaagat
      421 gaacctgatt atcttcaatt aactgaatgt gaattcatct ctgtcagcaa agcttattca
      481 ttaaaaaaac aagtattagc ttattttaat gactgcggga tcgaaatcga ccgctactcc
      541 cctcgattca ctgaaatgga aagacgtctg ctgcttctta atgtgtcgta tcgtttaggc
      601 ggttttaatt cttgggagct acctgaatcg ttttttgaac gtgccgatcg tttcattgaa
      661 tccgtaacgg aaaatagtgg cagattttat gataaagaaa ataaagaaat cttatcgatt
      721 ggttttgcta tcagtttcct acgccagcaa gtgtgtgctg tgacaataga ttcaaaattt
      781 atcgaagaaa tcaaaaaacg tcctatttac aattatgtcg aatcagcatg ggaaaacact
      841 gatttccaaa cctattataa aaaagaagaa ttcgccttta ttttgacact attcaatctt
      901 tgtaattatg gtttccattc ttatcagttg attgcggaag actttcaaca gctacaccaa
      961 gtgtttattg acaatactcc cgaaataaaa gaactagttg ctacctttga atctcacttc
     1021 aatcaagaat tattcggaaa ccaaccgttc gaacgtgcgc tgattcatct gatgcgttcg
     1081 gcttgggata actatcaatt attcatgcca gaaaaatttt atcttttaaa tgaggaacag
     1141 acaaatttat ataaagaagt ccagacaatt ttttccagct ggtccagcca gttaccttat
     1201 gatctacggt tgaatcctaa ttgcatgcgg gcttttgtga tcgaattgag cggaattctc
     1261 cgtctgacaa aagaacatct gactatctat atcgtcacaa attcggatgt tcattatctg
     1321 atttatcggg aagccttgga agctgtaact actttcgatt ttcaagttgc accaacaatt
     1381 tattcaagta tatctgatat aaagaagtat gcgcagcagt cctcaaaccg ggtattatgt
     1441 gaacgtacat tatatacacc agatgcggtc caatatgaaa atattattcc tatttcgatc
     1501 aatacgatcg atcgagctat catttcagct gtgcaaaaca aataaggggc tgtgacaaaa
     1561 atcatgtcac agcctcttat ttgttgaaga tgcccatttc tgtaacaatc tcttgataca
     1621 cgtcaggctc acaacctcac ttattttgga catctacggg tccgatctct ttatttaaaa
     1681 aataagaaat gatggttcgg ataactacca acgccgctag ttggaaaata tcctgcaagg
     1741 taggtttgat aatcgattcg atgatcccag ctgaaacaag aatttccaaa cttagaagta
     1801 tatagcctcc caacatcttt ttaatagcat tgttctcgct gactcggtcg ctttgcactt
     1861 ttgtatggac aaataaatat ttcaaaaaat ccttgattga tagacaaaca ccccaaacca
     1921 ataaacagat agcaaagata tcaagtccca gtacaagttt ttcgaaatat ggaagaagaa
     1981 actgcatcaa ctctgtcgtc atcctacctc tcctcttctt tgtttttctt tgtcttctat
     2041 ttcctgattc aagaaataag aaatgactgt tcgaatgata ataataagtg caagcttcaa
     2101 aatatctgtc caagtcggct tgataactga ctcgatgata tcagcaacga ctagtacttc
     2161 caagcttaac aaaatataac ttgctagcag ttttcttgta tctgcattac gagtattacg
     2221 ttctgcatag tttttcttga catgagacca atcaaaaagt ttgaatagaa caagaacgat
     2281 cccgacaatt aagataccga tagaacaaat atttaaaata gcaatgatcc attctagaaa
     2341 ttcaattaaa tttgagcgaa acatatacgc tacctacttt cttttaattt gttcctattc
     2401 ttttattgta aaagaaagtt accttgttcg tctatttaaa agttgttcta atgataacgg
     2461 ttcgcttaaa tttttctttt tcactctccc atttttctcc ctccatccat aaatcgtgga
     2521 agtatccaaa acaacgtagc aagttaaaat aaggcttagt ccgtcatcag cttttcaaag
     2581 aagcactgtc tcggtgcttt ttttgtaccc aaatttctaa aaatagaacc atacacctcc
     2641 tcaaatcttt tcttcttacc taccctattt ttatttacag gaaaatcaga cacttcttct
     2701 tttttgtcaa aatttccttt ttcttctcgt cctatcattt ggcattctaa taaaaacgaa
     2761 ctatccttgg atatagaaag agaaaacaag gaggcgtttt tcatgagtaa aaaattaatc
     2821 aaagtcggca tcggtttagg tttgcttgcc cttggcgctg catatctagg aaaaaagaca
     2881 ggactattcg aagatgacag tcatttatat gatgaattcg aatcaatcta gcatcctatt
     2941 tagttgaatc actacggaca tacttggaag acattggagg aatcacaatg agaaaaagta
     3001 aagcaataat gattggtgcc ggtattgcca atatggcagc ggctgtttat ttgattcaag
     3061 aaggcaaatg gaaaggggat cagatcacct tttattcatt ggatgatcac ggttcaaatg
     3121 atggtgcacc gaccgacact gtagtggatg aatattggaa taaaaaccat ccattagaaa
     3181 accaaaaagg ctatattgct cgaggcggtc gcatgcttaa ttaccgtacc tatgtagatt
     3241 tgatggatct gttaagtcga ataccttctg ttactgagcc agggatgact gctgaagaag
     3301 atacgagaga ttttgatgca aaacaccgaa cctttgacaa agcacgtttg atggaaggtg
     3361 gcaaaggaat cattgatggc ggaaaactgg gattcaataa taaagaccgt attcttctga
     3421 ctaaactgat tgctatgcct gattcagaag aagaaaaact agacaatatc actatcgaag
     3481 aatatttcaa agatgatcca cacttttttg aaacaaactt ctggtttatg tgggaaacaa
     3541 catttgcttt cagaacacgt agttctgctc aagaattgcg tcgctatatg catcaaatga
     3601 tttatgaatt cactcaaatc gaacatctag tgggcgtcaa tcgaacacgt tacaatcaat
     3661 acgaaagtat tatgcttcct ttgatcgagt acttgaaaga acaaggatgc aaaatcattt
     3721 tgaaccgccg tgtcactgac tgggaattca aagaaacacc gatgcaagat gaaatcactg
     3781 tgactggttt gaaaattacc aatacactga ctcaagaaga agaatacgtt gtggtcgatg
     3841 aagatacagc agttattttc actaatgggt ccattacaga ttcagctact ttaggagatt
     3901 acgaaacacc agctgtagaa aatatggatt atggtgcagc ttctagtctc tggaaaaaag
     3961 ccagtgaacg tttctacaac ttgggaaatc ctgacaaatt ctttgctgat cgagatgcaa
     4021 gcgaatgggt cagctttacc ctgacgacga aaaaccattt gttgttgaat gaaatcaccc
     4081 gtatcacgac tcaagaacca ggaaatgcct tgaattcatt tatttcaacc acaccgatca
     4141 cgccgttagg ccaaaaagat gtcaatatgt ctatcgtcgt gcatcatcaa ccgcatttta
     4201 cgtctcagaa accaaatgaa acagttattt ggggttattt cctttatcca agacgacgtg
     4261 gcgaatttgt ggataaacag tatattaaaa tgaatggaaa agaaatgcta gaagaactga
     4321 ttggacaact ttcaaaagta gatcctggac cagtgaatat tcgtgaaaaa gaaacagaaa
     4381 ttttcgacag cgtaataaat aatatccctg tctatatgcc ttatgcttcc gcgttgttca
     4441 ataatcgtgc caaaagcgat cgaccaaaag tcattcctaa acattcgacc aatctggcct
     4501 ttacaggaga atttgtcgag cagccttatc agatgatctt tactgaacaa agtgctgtac
     4561 gttctggaga aatcgctgct ttccattttg cgggtattcc tatgtcccgt cttgtcaaaa
     4621 caccgcgtta cgacaaagat attcctactc tagctcgtgc cgcaaaaaaa atgtttgaat
     4681 aatcaagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacaacc aggctaaaac
     4741 agcttcttat gtttttgatt tggttggact tattaccgca gatgcaagct tttgaacacc
     4801 gtttaccaag aggttgtgaa aaagctgccc tgcatcaagt aataagaaca cccaagctaa
     4861 aactgcttct tatgtttttg acttggttgg acttattacc gcagatgcaa gcttttgaac
     4921 accatttacc aagaggttat gaaaaagctg ccctgcatca agtaataaga gcagccaagc
     4981 taaaacagct tcttatgttt ttgacttggt tagacttatt accgcagatg caagcttttg
     5041 aacaccgttt accaagaggt tatgaaaaag gcgtttagtt tcgagtatga agaaaaattt
     5101 tgtgaaaatg gttcctcacg tttttgcata aatttgactt aataccgaga aactgatccc
     5161 ttctgtcata acctcttttt atttatgtct gtttcttttt gaaaacaact attttttcaa
     5221 cgtttactct cttgccaatc caacatcatc taacggatac aactatttca atgattacca
     5281 ttacactaaa aaatcggaaa cacacctctc cgaacacaaa tacataagac tatagaatgt
     5341 ttcatttaag aaaaaaagcg tttcattatc aaaaaggtaa gatctccttt aaaatgaaat
     5401 tatctgtagt actaataatg cagacaattt tatgaatctg aaaggagcat ctccaatgaa
     5461 agcagtcact tggcaaggaa aacagaaaat ggaaatcaga aacgtagatg atccaaaaat
     5521 attagaacca acagatgcaa tcatccgtat cacagcaaca gccatttgcg gctccgatct
     5581 gcatctttac catcatggtg aagcagtttt ggaaaaaggg tatgttgtag gacacgaacc
     5641 aatgggaatc gttgaagaag tgggatctca agttcaaaca ttgaaaaaag ggcaacgtgt
     5701 ggttatccct tttaatatta gttgtggtca ttgtcatttc tgcctgaatc acatggaaag
     5761 ccaatgtgat gaatcaaatc cagatcagtt atatggcggg cttttcggat ttggcaagtt
     5821 gaacggtaat cattggggtg gtcaagcgga atatctaaga gttccttatg cagactctac
     5881 ttcatttgtt gtaccagata atgatcttcc tgatgaaaaa gttttatttc tatcagatat
     5941 tttgcccaca gcttattgga gcgttgaaaa cgcaggagta aaaaaaggcg atacagttgt
     6001 gattctaggt tctggtccag tcggtctatt cgctcaaaaa ttcgctgtta tggctggagc
     6061 agagcgcgta atcgcagtag atccagtaca gcaccgtcta gataaagcgg ctaattacaa
     6121 tggggttgaa acttatttct tagaagacac ggcacaagct ggaacagaat tgtatgaact
     6181 ggctaaaggt ggcgcagatg tcattatcga ttgtgtagga atggacggat tagagcctgt
     6241 caaagaaaaa gcgaaaaatt tagtaagctt acaaagcggc acaatctctc cattacagat
     6301 ggcatcgcaa gctgtcaaaa aatttggaac agtccaagta actggtgttt atatgactcc
     6361 agcttcttct tacccgctgc aagaattttt tatgcgggat atcgctgtca agcatggaca
     6421 ggcaccaatt atccatctaa tgccaaaaat ttacgcaatg attgcagaag gactattcga
     6481 tcctacacaa atcattactc attcgctgcc actatcagaa gcagcacaag catatgagat
     6541 ctttgacaaa aaagaagata aaaatataaa agttgttttg aaaccttgaa ttcagtaaaa
     6601 aatacaggtg attttcttta tgcccaaaat caaacgaaat acccatgaga tcgaaatagg
     6661 aaaagaagaa gatatcgaaa tacgaggacg tcgcttccgc ttctatttcc aaaatcgtta
     6721 cacattgatc tcactggctg tcgatttatt aaccgggatt ttctatattt ttggaagcct
     6781 tgcttcctta actaaaatcc ccgatcgata tggcacctat ttttatttgg ctggtgctat
     6841 tttcttgacg attcgtccta ttctcagaat cgtaaggaac atttttattt acgacgaaaa
     6901 aaaagcaatg aagagaacaa gcaaaaaaaa agaggcatga gaatttttca aatctcatgc
     6961 ctcttttttc accctatcgt atcactttga tacagacgag cggtcgtccc actttcttcc
     7021 ttgaccattg tcaaaaatgt ccactcgtat cgttcataaa acgtggtatg atctgtaatt
     7081 aagtaaagtt tttcgtaccc aagttgatgc atttcttttc tgatttccgc taatatccgc
     7141 ttggctatcc cctgcttacg cttttccggt tcaacaaaca gggcacaaag atttggtgtc
     7201 agatcagggc ggttatggaa gtcgttttca atgacgcccg ctcctccgac gatggtttct
     7261 ttttcatcta agaccacata ccattgagga atactttcct tattagcgat tccagtacga
     7321 atactttcct catacacaac agcaggaact ccccattttg atgaaaacca attcgcgctt
     7381 tgttttacta attctgggtg ttctcttaat ttgatccagt tatatgtaac caatgtttaa
     7441 acctccgact aaaataaaac gtttacaaaa attatacaag tctttatgaa aattagcaat
     7501 gacaacaata gtgatgtaaa aaaaaaacgg aaaacaatca cttgttctcc gttttttgat
     7561 taatcaagca tctaaagctt cttttcttct ttcttggatc gtagctacct tgacgaacgg
     7621 tagatagatc aaaatagaaa gaaccaaatt gacagcggct agtacaccac ctgcaatact
     7681 ttttgttgcc aatacaccgc caataattgg tggagttacc catggaggca taacggtagc
     7741 tgctggcact aaacctgtag aagtcgcaaa gtaagcaaca ctaactaaga ccattggtgt
     7801 caaaataaat ggaatgaaca tgatcgggtt caacacgata ggtaacccaa acatcgttgg
     7861 ttcattaata ttgaagacac ctggcgcaat cgacaagttt gttacaacca tatatggttt
     7921 gtttttacgt cctactaaat aaatagctaa cagtaaacct aaagttgcac ctgttcctcc
     7981 taagttgaca aagctgtcaa agaaaggttt gttcacgata aacggtgcgc tatgcccagc
     8041 tgcgattgca ttaacgtttg cttcaatggc tggcgcattg attgtttgca tcaaaggatc
     8101 gaccatattc gctccgtgta aaccaaagaa ccataagaat ggtgtgataa atgcaagcag
     8161 taaggcagat ggataagagt ttgcaagtcc cataaatggt tcttggacca ctgtatagaa
     8221 agaacctacg atatcatcaa caccgaatgc agcaaaaatt gcagcaacta aagcaaacgc
     8281 agagatagtg atcattgctg gtagtaatga agcaaatgct tttgcaactg ccggtggcac
     8341 accatcaggc attttgatga tcaatttttc atttccgctt aaacgtacaa agatttctgt
     8401 tgaaataatc ccaacaataa tagcaataaa caaaccgttt gagctcatac ctaatgctcc
     8461 gcctaaagcg aagaaagagc ctaaagaaat cacacctgcg gaaacaccgt cttttcggta
     8521 gccgttagct aaatgataag caagcaagaa agcaatcaag acagaaagaa tggcaaatgt
     8581 accgttccaa gcagcagccc cgaatccttt ccatgattca ccaccaaaaa ttgagttcat
     8641 caattcttgg aacccgggaa tcggtaagtt attgatcatt actgctaatg ctcctaagat
     8701 cattaacggc atactcacca taaatgagtc ccgaatcgca actaaatgcc gttgtgcacc
     8761 aatttttgat gctacaggta taaaatgttt ctccataaat gcaacaaatt tatccataaa
     8821 tcttccctct tttctttact gtagattacg cgttcaatcg acgatacaga tcaatgatct
     8881 cttttgctaa atctgtaaaa gctatagatg tcatcagatg atcttgactg tggaccgtca
     8941 aaagcgtgac ttcaacgtga tttccttgtg cttcttgtgt cagcatctct gtttgagagt
     9001 gatgtgcttg gactaaagat tcctctgcat ctttgatttt ttcatctgct aaagtgaaat
     9061 cacctttttt cgcagcagca atcgcttcca ttgcatcgct ttttgcattt ccgccaaaca
     9121 tgatcagacc catgatggct tctagatttt tttgatcttc catttattgt atcctccgat
     9181 aatttttatt atttgtttat tagtttttct gcttggtcga gtactttttc accattcatc
     9241 atgccatagt cagccatatt gattacatct aaaggaatgc ctttaggtgc tagcttttca
     9301 gcaaattgat tttgcataaa gcgtacttgc ggtcctaaaa gtaaaacgtc tacattttta
     9361 gattctagtt gattatccgc atctgaagca gatacagcaa agatgtctgc ttccattcct
     9421 tttgcttctg ctgccttttg catttttgtg actaggagac ttgtactcat tccagctgaa
     9481 catacaagca tgattgtttt cttttccatt ttaaacacgt tcctttctat acttacactt
     9541 gtatataagc aagtagcgtg ccaactttaa aagcgcttta aaaagttgat atcatcacat
     9601 ttaaggtcta taccaagttg catacacact aaaaaagaaa gcgcacacta aacacacaaa
     9661 ttaattttta ttaccttttt tcttttaacg tgcacaaaaa aagttgtgac acaaaacttg
     9721 tcacaacttt tttcaaataa acggtattca aaagcttgca tctgcggtaa taagtccaac
     9781 caagttaaaa acataagatg ttgtttttac tttgctattc ttattacttg atgcaggaca
     9841 gctttttcac aacctctcaa taaacggtgt tcaatcagct gaccctgggt attagctcaa
     9901 aacgctggat tcacaacctc ttttatttca aataaccagt aaatacaatg aacatctaca
     9961 aaaaacttct atttatttat agatttcgtc aggcaaatcc aattctctct tatcaatcaa
    10021 agtctgatac cacgaagcag attttttcaa tgttctgctt cgttcatcgt tcaattcgat
    10081 tcgaactaat ccatatcgat tcttaaatgc attcattggt gacacacagt cagtgaatgc
    10141 ccataacata tagccttcgc aatttgcgcc ttcttctgtt gctttgatca agtaatgcaa
    10201 atgctgtccg ataaattcga tacggtaatc atcttgcacg attcctttct catccatata
    10261 ctgttcttca tattctcttc ccataccgtt ttctgttatc agccaaggga tattatgata
    10321 attttctttt agatacatgg ctatatcata catgattttc ggatagattt cccatcccct
    10381 ggaattattc attttcttcc caggtaaatc aaagacttca taatatcgtt caggatggaa
    10441 aggtgtctct tcattccatt gataacgagg ggcgcgaacg cgtttaggat aatattgatt
    10501 gattccaagg aaatctactg tatgatgctg aatcgtttct aaatcctctg ttgcaggatc
    10561 gaaataaatc gattgttttt gacacaactc caggaactct tctgtgtagt atccttttac
    10621 catcggatca aaaaatactc gattataaaa caaatcatac atataagcag ctttttggtc
    10681 ttctggagaa ttggatcgag catagaccat ttcaggattt aaaatacagc caatccttcc
    10741 accataattt ccgctgcggt aaatctctac tgctttagcc gttgctaaaa ctttatgata
    10801 attccacatc atccactttt ttgtgttttg ttcatgcggc cagcgaacag catccaaata
    10861 gcaacgcgtt tggggaacga ttggttcgtt gaatgtaaac cagtttttta ccctatcacc
    10921 gtaacgatca aaggcaattt gagcatactt agcataaaaa tcaactactt ttcttgaaga
    10981 ccagccatca tatttttcca aaagaaaagc tgggacttca taatgttcca aacaaatcat
    11041 cggttctacg tctgcttcga tcaaagagtc gatcatttca cttatatgct gagcatattc
    11101 ttcatctact atacagttct cataatcagt aaaaaaacga gcccaattga tagaagtccg
    11161 ataatgtgtc agatggatgg atttcatcag atccacatcc tgctggtatt gttccataaa
    11221 attagttgct acggctgggc catacccatt atgccaaaca aaatgttcat ttttatacca
    11281 gctatctata aacgaatcct gtccttcttt ttttcctttc caaccttccg tttgccaagc
    11341 agaagatgca gcaccaagaa taaaattttt tggaatagta attttcatga tttcctcctg
    11401 ttttttagat cccatcattt tccacacgat ttgctacttt tacaaatggc agatagatca
    11461 aaatagaaac aataatacaa acaagttgcg taataactgc accgatattt cctgctgttg
    11521 ccagataagc attgacgatc ggcggcattg gccaagggac cattacaact gctttcgccg
    11581 caaatcctaa agcggttgca aaataaccaa tcgttccagt gataagaggc gttaagataa
    11641 acggaatagc taaaattgga ttcagcatga tcggcatacc aaaaataact ggttcattga
    11701 tgttgaagat cccaggagca agggataact tggtgatttg tttcatatct tcccgttttc
    11761 caactaacaa tactgcaatc agtaaaccga tcgtgactcc agacccgccc atactcatat
    11821 acatatccca aaatggcata gtaataatgt tcggtacttc ttttccagct tcaaaagctt
    11881 ccgtatttac agcaattgcc gctaaaagca acggttcccg tatcggcttc accatttgat
    11941 ttccatggat accaatcacc caaaagactt gcgcaataaa catcaatagc aaaatacccg
    12001 gtaacccttg tacgacacct tctaatgggc gttgtacgac attgtaaatg atatcataaa
    12061 ggtacattcc tgtaagttct ttgatgataa atcccgcagc cgcgataccc gatacagtca
    12121 gaatcgtcgg gaataaagca gaaaaactag cagaaacatt cgttggcacg gtatcaggca
    12181 ttctcagctg tagtttcttc tgtttcctca accagcaata aagttcaata gaaaggatgg
    12241 agaccaacat tcccaaaaat aaccctttcg tatctgtata ttgtttagcc aatacgtttt
    12301 ctactataac agtctgattt tcattcacta attcataaac agttggatta acagataaat
    12361 aagacatcac tgcgatgata ccagggaata caccatccac tttattcagc ttggctaatt
    12421 cgatccctat cagaaaaaca gcatagatgg tcaagaaact tagtgtgaca tagctgatgg
    12481 cagatgcgat aggctttaat tcttctaaaa aacgcaagaa acttatctgt gctaagccat
    12541 tttccgagtc aaagaccatt gctgaaaaca atgtgccaaa agcacccgta ataattaccg
    12601 gaatcaatgc agcaaatgcg ttttttatca ccatgatata ccttaaatta ttgattctcg
    12661 ttgccacgtt ccctaaaaca ttggctaatt tatccataaa actcattcca gatcccctca
    12721 ttcctgcttc ttctccttga cgtcatctct ttttgtctat tagtcagcgc ttacatttcg
    12781 atgaacagaa actatttact cctctttttt accaaatata aaacaaaaat tcatctgatg
    12841 tatttatcat aaaatacatc agatgaactg tcaattagtt tctttttctc ctattatttt
    12901 ctgtaattct ctccgattta ttgccatatg gacagtcatt gcatcaaacg cagcaagtgc
    12961 attccgcctt tcgatggcct gaacgatctc tgtatgaata tcgatcgtct cgattttcag
    13021 atgctggata tcataatttt tattaaacaa agcaattgat tcattaatga ttgggataat
    13081 atgcagcaag gctacgtttc cgctagcttc tgcaatcatc gtatgaaaat cgatgtctaa
    13141 ttgaacatgt tcttgtgtgc cttctcgaaa agaagtttca atcttttgcg ttaatttttt
    13201 catttggacg atttgattct tcgttgcata ttccgctgcc aaacctgcca tcttaggctc
    13261 caataaatat ctcagttcaa ataagtctcg tatcatccga tcctgatctt caatcaaaga
    13321 aaaaccgagt gggtcattgg caatccctcg cttatcactg acaaatgtcc ccgctccttg
    13381 ccgaacttca aggatattcc tggaagctag agcccgcaca gcttctcgca ccgtgcttcg
    13441 ccccacctct aaataatcgg acaattcata ttcattcggc agtttatctc ctacttgcaa
    13501 ctgcatttcc tttaaatatc taaggatctt gtcagtagtt acttctacta gggttttatt
    13561 ttcttccaaa ccacatacct ccttttcatc tgatgtattt tttcgtaatt attataacac
    13621 gtttgaatca tctgatgatt ttttgtatac aaaattgatt aatccgttca tagacataca
    13681 aacgaagaag atatttacca taaaaaagac taggataaaa ttcactccta gccttcgatc
    13741 atttttattt tgaacgacaa aaaatatgat gttcaataac agacgatctt cattcgattc
    13801 ttgatgtcat cttttgtttt ttttaatata tggataaaaa gtttgattac atcgtttcta
    13861 ttctagaatt tggtcgattc tcaattcttc ttctggtgag aaatctaaat tatccatcat
    13921 tcgaacactt tcttgtaact gacttaaccg acttgctccg accagtacac ttgtaacaga
    13981 tttttgtcgc aaattccatg caagggccat ttgcgctaat gattgtcctc gtgatacggc
    14041 gattgtttgc agtgctttga ttttttccag agttgatcca acttgttctt ctgaaaggaa
    14101 tggtatttcc ttacgatgtg ctctagaatc ttcaggaata ccatgtagat aacgatttgt
    14161 cagcaaccct tgagcaagcg gactgaacgt gattgcccct agcccttctt cttctaatac
    14221 tggagataga tcgtcttcta gtagtgcacg agaaaacata ttgtagcgca tctgatgaat
    14281 aatgaacggt gcttcctttc tttttaaaat ttcagtcatt tttttgtatc ttctccatta
    14341 tagttggata taccaatata taatgctttt ccttgtctta caagttgcat caacgcttct
    14401 gctgtttctt ccaaaggtgt atcagggtct gggcgatgat gatagaagat gtcaacataa
    14461 tctagcccca ttctttggaa actttggtca caacttgata tgatggattt acgagagccc
    14521 cattccccat atggcccttc ccacatatga taacctgctt tgctagaaat aatcagttca
    14581 tcacggtagg cttgaaaatc ttctctaaaa atacgcccaa agtttttctc tgcagctcca
    14641 gcagggcctc cataattatt cgcaaggtcg aaatgggtaa ttcccatgtc gaatgcgcct
    14701 cttaaaatct ctctttgatt atggatagga tcataatcac caaaattttg ccataatccg
    14761 agaggagaga taaaatcggt aattttaaac ctgaatgacc ggatttacga tattccattt
    14821 tttcataacg tgcactatct gcaatataca atttttctcc tcctcatcaa atctttttaa
    14881 aacgctttct tgttttctat ttttagttta ctacatttta aagaaaagga gttaatcaaa
    14941 atgatttttt cgtatatttt tttgccattt gttttttact cgttgataga tcagaaattg
    15001 attacgtgct tgctggattt ttttatagcg tttcggttgt tttttgtaaa attgctgatg
    15061 atagttttct gctggccaaa acgtaccggc tggttcgatt tttgtgacga ttggttggtg
    15121 gaaagttcct gaactgtcta gtttctgttt tgattgttcc gctaattctt tttgtcgttc
    15181 gtcttgataa aaaatcactg gacgatattg cttccctcta tcttgaaatt gtccaaatgt
    15241 atctgtggga tcagtaattt gccaatagat tgtcagcaac tcgctataac ttatttctct
    15301 tgtgtcataa atgatctcca cagcttccac atgacctgtg taaccaccac ttacttgatc
    15361 ataattcggt ttttcaacat gtccgcccgt gtatcctgac aaaacagata ggatcccttt
    15421 tttcgattca aacggctcga ccatacacca gaaacatccc cctgcaaata ctgcacgttc
    15481 ttgatagtca gcatcttgca tggcatgctt ggaaaagtca tatttttgct ccttatcaaa
    15541 tccttccgta atcaataaat aaaagtccat tacatcaggc gtcagattca ttcggatagc
    15601 taatggacgt agtgttactt ctagttttga taactgttct ttaacggata tattttctct
    15661 tgtgtcattc tttgtctgaa tcaatacttt tcgttcccaa tctcgtgtat tcggattcaa
    15721 aatcagatta taaagtgttt gaatgaatat ttgttcctca tccatagatt ctcctccttt
    15781 ccgaagaaga caagctagtg actttagctg taatttatca taaagtgagg aaataatcga
    15841 ttgaatcgta tttattcaaa gaagataagc agcttcagat gatataagat gatctttatc
    15901 ttaaaaagca tactctatgg tttggtttaa ctaaaaaacg acctctgaaa aaagggatgt
    15961 tctccaattc tcagaagtcg agtaaagatg attctttttt atgagcgata ataaacttca
    16021 tccaaaaaca gaccttgtgc agggacggtt tctcctgcat gttgccgcac tttgctttca
    16081 aatatttcat cgattgtttc tatcggcatg gcacctgtgc cgatttctag taatgtcccc
    16141 atgataatcc gcaccatttt atataagaat ccgtctccga caaaagtaaa atgaagcatt
    16201 tctccctttc gttcgataga taattcatca atcgtacgca ctgtggattt ttttgatttt
    16261 ttcaatgcag aaaaaccaat gaaatcatgt gtacccacta atttttcgca agctgcattc
    16321 agcttgtcca tatccaactc ttgagggaaa taaaagctgt ggtttcgctc aaatgctgaa
    16381 ggaatcacgt tgttccaaac ataatagctg tattttttgc ccaccgcatt atatcttgaa
    16441 tggaagcgct caggcatttc ttcgattctt ttgatgacaa tatcccgcgg aaggtaacga
    16501 ttcataaagt cgatcatttc tgccagtcca atttctgtgt ttgttttaaa atttgctact
    16561 tgtcctcgcg catgggtgcc agcatctgtt cttcctgatc caataatttc tatctcttca
    16621 tttgtcatct gatgcaatac tttttcgatt tttccttgaa tggttttatc gtcatctcca
    16681 agtctttgcc atcctgaata tctttttccg tcatattcga ttgtcaactt gatgtttctc
    16741 atattttagt ggctcctctg tcttccattt ggtcttctct ctaccttttt aagattgtag
    16801 cacaaaatat agctccttgc ttctctaaga cagaagctat acaagaaaac tgtggaaata
    16861 tatatttcag aaaaacaaaa aacagccacc ggatgaagta tccgctgact gttcaatttg
    16921 acggctcaag ttttactgtt tgagatgcaa gatactcaac caggcaatgg gcacataatt
    16981 aaagaaaaaa ctgattcttt ggcaaaaacc tattttattc agtaatggcc aagaatttat
    17041 agaaggaatt cttgccagtc cataaatcgc cgcaaaaagc aaactgatca cagacagtcc
    17101 aaggtataag tggcttacgt ccatttgccc attttttcga tagatcaaga aaagaagaac
    17161 tggaaacaat aaaaaaccac tgtaacctaa acctgatccg atattatgga cccatgtcga
    17221 gacattccac gaagattcat gggtattgat actgaacaaa cctgtaaaga tacaatcacc
    17281 tataccatag aacgcgatgg ctgctgtaac tagggtagct aacacacgag atgtacttac
    17341 aaatgcagca tacaatgcag gcaatgacag gatgaaaaag atccctgaaa ccacagacca
    17401 aataagaaac gcttttctta caggactgga aacctctcca aatacactga tcacgctctt
    17461 catttgatct aattcaggat aatacaatcc taatacgtac ggagtcaaaa aatcactcag
    17521 cacgcctaat aataaaaaga aaaaaccaaa tttacgtaaa aaatccatga tacgcctcca
    17581 ataacaatta cctatgcttt taattgttat tataaacgac tttatcttga tttaacagaa
    17641 acctctattt acacgaacat ctatataact cattaaaaac tcgaatcatt ttaaaaatac
    17701 taaatatcta acgttcaacg ttcacttaat ccatctaaac aatctttcaa tttgattttt
    17761 tccccacttc ttttacgcgc gcctagctct cctattgcag taaacaacag atcacttgac
    17821 gaatttaagg cagtttccat tgaatcctgg ataacaccga taataaatcc aataccaacg
    17881 atttgcatcg cgacatcatt agagatacca aacaaactac atgctaatgg aatcaataac
    17941 agtgaaccgc ccgcaacacc tgaagctcca caagcagcta aagcagacaa aatacataaa
    18001 aggactttca aaacaaatgg tgcttcaatc cctaaagaat gtacagcagt caacgtcatc
    18061 aaggaaatgg taatcgcggc accgcccata ttgatcgtag cacctaacgg gatcgatatg
    18121 gaataagact cttttgtcaa tttcaatctt tcagccaaca tcatgtttat cgggatattt
    18181 gcggcagaac ttcgggtaaa gaaagcggga agtgcgcttt ctttcaaaca aaagaaaatc
    18241 aatggatagg gattttcttt aataaacaaa aacgtgagga atgggtacac aactaatgcg
    18301 acaaacagca tcgtaccgat caaaacaagt aaaagctgca gatactctgc caatccagcg
    18361 attccagtcg tagcaattga ttgataaacc aatcctaaaa tccctatcgg agcaaatgca
    18421 ataatcactt gtacgacttg tgacaacgct atagatatct gatccaccaa ctcttttgtc
    18481 ggttctgaac gtgctcgaaa agctagtccc aacaatacag cccagaataa aacgccaagg
    18541 taattcgcat caataagaga ttgaacagga ttttgtgtga cattcgtcaa catagtagat
    18601 aaaacacttt ccaaactttg cggtgctttt tcagatactg tttcttgtaa agtaatagga
    18661 acagtaaaaa ttgaacttac aatgactgct acaagtgcag aaagcaatgt tcccactaaa
    18721 tataagatca aaataggctt cacgaatgtc ttattcccaa ttttatgctt ggcaattgac
    18781 gccatcgtca agaaaaaaac cagaataggt gcgattgcct tcaagcaact gacaaacaac
    18841 gtccccaata ttgaaataaa tgtccacgtg gggaaaaaga taccaaacaa tattccgact
    18901 aaaataccaa caacaatacg ttgaactaac gacatatcca aaaacttctc taacaaatga
    18961 ccaccctttc acaattttaa caatcattgt atcattttat ctaaagaaac taaaggtgca
    19021 attttctaaa aattctaata atacaattgg caattcatgc tcttgcaaca ttcaatttta
    19081 gtattggagg gtttattcaa tctctaaaga agtcgagaga aaactattta tcgttattat
    19141 tatagttatc caagtaaaac gtaactaaga tgaaggacga aactagaaat ttcatccttc
    19201 atcttaattc ttagacatag caatcaatta atattttcca ctgagtctct tctttctctc
    19261 actctcactg gtttacttac ccataaacga tttgattaaa gccatttttc aattcattat
    19321 tcgctgtctc gttaaagtaa agataattat cgggattccc ctgattttgt tgtgtcacca
    19381 atacttttgg ctgattttgc tgaaacccga atagatagac gtgctttttc agatatggtt
    19441 ctgtctctgc atcggaatag acggctgtga tttgatagtc tgcttgacct gtcccacttt
    19501 ctgaccattc tgcagaaaca ggcactccac caatagccat cttccactcc ccgttcaaaa
    19561 taacttgagg gactttaaga ccatataagt ccacactcat ttgattcgta tagcttttgt
    19621 attgttgtcc cattgtttgg ccccatgtag ccataaatgc ctctaattgt gcggatttgt
    19681 ctgcattcca cagtgtttgt tcgacttgtt cgctgctttc tgaagatgaa gcctctacag
    19741 aagaacttga agtagatgtt tgagttgttt cagtcgtttt ggaagactct gacgaagtag
    19801 aggtatctgc tgtttccgta cttgctgcag ttggcttgct ctctgtgcta gttgttgtag
    19861 tagttgcaat tgttgctttc gctgtttctt ttgttgattc ttttttcgat tcattcccgt
    19921 tggtacaacc agctaacaaa aaagctagac caattgttac taaaatcctt tttttaaatt
    19981 aaaaaactcc tttcgattac tcccacttct ttattctatc aaataagcaa tgtgatttta
    20041 ttgatttttt gtattttctc atccatcttt taaacctttt aaaaactaag aagcacccgc
    20101 tgatgttgtc tgtaatacat cagcgggtgc ttcttttatt ttaatcttcg cgattttcca
    20161 atttacctca cgctttatat ttgtatttga agaaacatag acttttagtc atcatcgtct
    20221 tcctcatcca aatcttgtcg gacagttttt ccttggagtc tttgtacttg gtagatgatt
    20281 tctttattga aacttaaaag ttcaacaagc aattgtttca agccatattt ttcttctttt
    20341 tcagctaatt tgattgcccg tgtgataaag acattttgga aatcaaaatc ttttgcaaag
    20401 ttttccaaca ttgttgaggc tggtaaatat ttgttttgac catgttcgta aatttttcca
    20461 taacgcatga cttcttctaa agtagacgga acgatttcat tttcaatcac taactcatga
    20521 gagattttat tgaaccatct cgcttcttga tcagcatatt ctgaaaaaag ggtacttaat
    20581 tcttgcgaag atgtacccaa aacatacaat tgtgcttgga tcaatttcat ttcttctaat
    20641 ttaaaatttg ccaatacatg ccccaccatg gcgccagcag ttggtttatg atgatcgata
    20701 tctgcttgtt ttgtttcttg agcaaatttt tcttccacta tattcactga tttacgcctc
    20761 ttttactttt gttgattgga cttcataacc taatttttcc acaactgcag ctaattgttc
    20821 agggtggact tcatctggat caaagtttgc tttgattttg ctcgcattaa acaaaacttt
    20881 cgtattgctt accccaggct gttgagaaac cgcatgttct attttttgca tacagcttgg
    20941 acaagctagt gtatctaatt gcataatcat ttttttcatc gtagttcttc cttccttttt
    21001 cttgatagtc ttattctaga ttacagcttc cataaaaaaa ttgattctta tcaagtttta
    21061 cgatttttct tctttgcttt cgtgtccaaa atacaataaa cgcatcgcgt taaagataac
    21121 gatcaagata ctagcttcgt gaacgaacat cccactagcc atgtaaataa acccggcaaa
    21181 taagccgatg agtaaaaata agacgacacc aatggcaatc actacatttt cacgggtatt
    21241 caaaacagtt ttcttagcca aacggtaagc atgaaccaac gatccaaaac tagattgcat
    21301 caagacaacg tcactcgttt cgatagcgac atccgttcct gatcccatag caatcccgat
    21361 atcagccgca gccaaagagg gagaatcatt gattccatct ccaatgaaag caacgtgcaa
    21421 tccttgttct tggtattttt tcacaaattg aaccttttca tctggcaata attcagcatg
    21481 gacttcatca atgcctaaca tgtcagctac ataatcagca gtcatctgat tatcacctgt
    21541 cagcatcact aaatgttttg ctcctgcttg tttcaacata gctaattgtt cagcgacttc
    21601 tggtcgaatc acatctgaca caccaatgat ttgagtgatt tttttgtcga ttgctacaat
    21661 aatgactgag ctgcctcttt gttgtaattg atgtaaatct tgtacttgct ttggtgtgag
    21721 agaaagtttg tgagcggcaa tcaatttggt gttgcccgca caaactgtat gaccatcaat
    21781 ctcagctgtg attccttgtc ccttgatcgt ctgattatct ttgactgcta attgttgaaa
    21841 atcaatgtct ttctcctgag cataatggat cacggcgcgc cccagaggat gatcggataa
    21901 cgtttctaat cgagccacta aagctaagct gtccccttca tcctctgtat agttcttgat
    21961 agtggataca gcagtagttc ctttggtcaa tgtaccggtt ttatcaaaga caaaagtatc
    22021 gattttggaa aaagtatcca ttgcttcacc gcctttgact aagatgcccc gtttcgctcc
    22081 attaccgatt cctgctacat tcgaaacagg cgcaccaatg actaaagcgc caggacaacc
    22141 aagaaccaaa acagtgatgg ctaaacgaaa atcacgactg atcagaccaa caagcaacgc
    22201 aataagtaaa acggttggag tataatactg agaaaattga tcaatgaatt tttccgcatg
    22261 tgatttggta tcttgtgctt cttcgactaa ttctataatt ttggcaaagg tcgtatcatc
    22321 tccgacctta gttgcttcga tcgtcacgta gccatctgct aaaatcgttc cagaaaatac
    22381 gttatctcca ctgattttga cgacttgtcg tgattcaccc gtcactgcgg cttcatccgc
    22441 ataccctttc ccgtcaatga ctcgtccgtc cacaggaata gctccaccag tttttactaa
    22501 gacgatatcg ccttcttcca cgtcatcgat ttccacttct tcggtcgttc catcttcttg
    22561 gacaacgctg gcagtcgatg gggccatctc ggtcaaagcc ttgattgatt cccgcgtttt
    22621 ggtcaatgtt ttttgttcca gataactacc aaacaaaaac aagaatgtaa cgatagctga
    22681 ctccttgtat tctccgatca taaaggcacc aagcacagca atagtaacga gtaaatcaat
    22741 tgagataact ttgactttta ctgcctgata cgcatggatt ataataggta tgaccgcaat
    22801 aatagaagct atggctagag caatgttata gaacaagaca aatccagtaa atttcccgat
    22861 aaaaccaaaa ataatcaaca cagctgataa ggcggtgata tgatttcgat gctcttggat
    22921 ccacttttgt aatttcatct ttctccctct tttccttttc attcttacga gactaagtat
    22981 agatacttat ccatcataaa aaattgacca ctatcaagtt tattcaaaaa ggcggttttc
    23041 ttttggtata ctgaattcct acagtcatta aacgatcata tagaaaaagg aagcgccgaa
    23101 acgcttcctt aggtagttct atttttttat tcaaagataa gatgctttgt catcttacga
    23161 ctgaagaaca acaatcaaaa aagggcagca gccactcatt cacaagaaat atcgtttttt
    23221 gatatgggag ttgaagcagt ggacaaatat ctctacttat tagctgggaa taagatccaa
    23281 aaaagcttaa tggattttat ccaagaattg gaatgtactt tccacaaaaa attcactcat
    23341 tccattcttt taaaactttt gattcataca gcgtgtctaa ttgagcgtac attgataaac
    23401 ggtcatgaac ttaaaattat atcagaagat gacacaagac cttctcatga aacaattttt
    23461 catgtaaaaa aggccttcaa aaatattgaa acagaatttg ggatcactgt ttcttatgat
    23521 gaatgtttct ttatctatga tattatcgca tctaaataat ctttttttat gtaaacgagt
    23581 attttgggag cgtcaataat tttgtgtaaa taaattgtcc tcctgcaaaa taattagtta
    23641 ctcagtaaac attgaaacta atgtatcggt tac
//
LOCUS       DACDAF010000042        23571 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.042, whole genome shotgun sequence.
ACCESSION   DACDAF010000042 DACDAF010000000
VERSION     DACDAF010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23571
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.042"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="IVZ69_001513"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="IVZ69_001513"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HAP8183601.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="IVZ69_001514"
     CDS             complement(1172..1867)
                     /locus_tag="IVZ69_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="noncanonical pyrimidine nucleotidase, YjjG
                     family"
                     /protein_id="HAP8183602.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="IVZ69_001515"
     CDS             complement(1880..2596)
                     /locus_tag="IVZ69_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HAP8183603.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="IVZ69_001516"
     CDS             2926..3531
                     /locus_tag="IVZ69_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HAP8183604.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="IVZ69_001517"
     CDS             3856..4179
                     /locus_tag="IVZ69_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HAP8183605.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="IVZ69_001518"
     CDS             4361..5731
                     /locus_tag="IVZ69_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HAP8183606.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5861..7162)
                     /locus_tag="IVZ69_001519"
     CDS             complement(5861..7162)
                     /locus_tag="IVZ69_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP8183607.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7392..9383)
                     /locus_tag="IVZ69_001520"
     CDS             complement(7392..9383)
                     /locus_tag="IVZ69_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter Kup"
                     /protein_id="HAP8183608.1"
                     /translation="MATTHNTKKISMAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGL
                     SGINPDFVIGSVSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLII
                     PAMIGGAALLADGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFM
                     VQRFGTDIVGKAFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKL
                     GLFILGNIFLATTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQN
                     PEAQQIKNLNPFFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPR
                     LKIMYPGNSIGQMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALL
                     YFYLIQNGHSRWLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWE
                     QGNIIRESSTEDVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSI
                     LDKRPKRARVYWFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQ
                     VIHDLMKQGRLPKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAI
                     KKIATSPETWFGLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9527..9793)
                     /locus_tag="IVZ69_001521"
     CDS             complement(9527..9793)
                     /locus_tag="IVZ69_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP8183609.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="IVZ69_001522"
     CDS             complement(10303..12429)
                     /gene="pnp"
                     /locus_tag="IVZ69_001522"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HAP8183610.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="IVZ69_001523"
     CDS             complement(12617..12886)
                     /gene="rpsO"
                     /locus_tag="IVZ69_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HAP8183611.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13137..13700
                     /locus_tag="IVZ69_001524"
     CDS             13137..13700
                     /locus_tag="IVZ69_001524"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HAP8183612.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13953..14474)
                     /locus_tag="IVZ69_001525"
     CDS             complement(13953..14474)
                     /locus_tag="IVZ69_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HAP8183613.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14477..15319)
                     /locus_tag="IVZ69_001526"
     CDS             complement(14477..15319)
                     /locus_tag="IVZ69_001526"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HAP8183614.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15312..16037)
                     /locus_tag="IVZ69_001527"
     CDS             complement(15312..16037)
                     /locus_tag="IVZ69_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HAP8183615.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16213..16509
                     /locus_tag="IVZ69_001528"
     CDS             16213..16509
                     /locus_tag="IVZ69_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183616.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17077..18669
                     /locus_tag="IVZ69_001529"
     CDS             17077..18669
                     /locus_tag="IVZ69_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750719.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP8183617.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18682..19422
                     /locus_tag="IVZ69_001530"
     CDS             18682..19422
                     /locus_tag="IVZ69_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP8183618.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            19590..20939
                     /locus_tag="IVZ69_001531"
     CDS             19590..20939
                     /locus_tag="IVZ69_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8183619.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(21067..21657)
                     /locus_tag="IVZ69_001532"
     CDS             complement(21067..21657)
                     /locus_tag="IVZ69_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HAP8183620.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            21804..23156
                     /gene="brnQ"
                     /locus_tag="IVZ69_001533"
     CDS             21804..23156
                     /gene="brnQ"
                     /locus_tag="IVZ69_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HAP8183621.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         6750 a         4746 c         4490 g         7585 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcacagc cttttttctt ttattctatt tttctttccg
     5881 tggactctac tttgaaataa tcgatatgtg catgctggta ttctaatacc gtgaaacgga
     5941 atgatgcaat ctcaatgatt gttcctgctt ttatttcttt atatcggcta gaagcaaagc
     6001 ccgcaagtgt agtaaaattc gtttcttcaa actctggaat ctctacatga aaataacgct
     6061 ggaaatcatc taatgttagt ttgccggaga tgatataaga gccatctgac tgttccgcta
     6121 tcaatgcttc gtccaaatct gtctcatctc ggatttcccc gacgatttct tctaaaatat
     6181 cttcaatcgt cactaagccg cttgtccctc cgtattcatc ttttaagata gcaatatgct
     6241 ttcccttttt tcgcatgatc gtcaataatt tttttatagg gatcgtttca gttgttacga
     6301 tcggctcttc aatcaactgt tctactgtca gctggtcatc tttataagat tgcttgatca
     6361 aatctggcaa ggtgacataa cctaaaacat tgtcttttga ttctaagata accggatagc
     6421 gagtatgtcc ttgttcaatc gaagctttta tcgcttcttt gacggtttct gaagcttcga
     6481 atacttgcat ggacgtacgg tctacttgta tatcttttgc caaggtatca tcaaattcaa
     6541 acacgttttc caaataatga tattcttctt tggtcaactc tcctttttca taagaattca
     6601 atgcgactaa tgtcagctct tcttgagaca atgtctcttc tccttcagat acgagacgca
     6661 cacctaatag cttccctagc cctgcagctg aatgattcaa tacccaaata aaaggaaaca
     6721 ttactttata aaaataatga agtggtttaa ctacgaacaa gacgaccttc tccgtattga
     6781 cgatactata gctcttagga agcagttcgc caataaccac atcgatatac gtaactaaaa
     6841 taaatcccag cgccacagag attgtactgc taatagccga actaaaaggt agtttaccga
     6901 tcactggttc tagtaaagcc gcgacagatc cttcaccgac ccacccgatg atcaaaccgg
     6961 ttagcgtaat tcctaattga ctagctgata aatagttatc taaatggtgt gtaacatgaa
     7021 gagctagctt ggcgttcttt acattttcct tttctagttg ttccaatctt gatcgtctga
     7081 ttttcactaa agcaaattca cttgctacaa aaaatgaagt aattgcaatc atcaaaaata
     7141 aaataatgaa attgataacc atattctccc gcctttctct ttttctattg tacccttttt
     7201 ctacaaaaag attgaaaata atgcgtattc atatttagga ataaaaaagg agatgcggca
     7261 tttttcagcc acatctcctt atcacttcaa aatcattgcg ttacttgttg ctaaacagct
     7321 ttttcatgac ctctgataaa cggtgttcaa gtagctgaca ttcgacatta gttcaggtca
     7381 aagcgctact ttcacaaccg ctctttcaac catgttttcc gagtatttcc aatgataagc
     7441 ggaacagttt catgttttac ttcgctgtac tctagcccaa accatgtttc tggcgaggta
     7501 gcgatttttt tgattgccag ttttgcctgc atgatttgac gttgccattt tcctagagtt
     7561 gtcacattgg aaactacttc atcaatcagg acaaattgga aatcgccaac ttctcgccct
     7621 ggtgtcagag agtatctttg tggctgtttt ggcaaacggc cttgtttcat caaatcatgg
     7681 atgacttggc gaacatatac gttgatttcc tgttggaccc tgaaacctaa gaacagattc
     7741 acttggacaa taaaatcagt gtccatcata tctacttgat attctttcgt atatggctca
     7801 tccgtcactt ccacatgaac aaaccaatag actcgtgctc ttttaggccg tttatctaaa
     7861 atcgaataga tgaactgtcg gccaacttta tcttcagcca tatcaggaac caagaagacc
     7921 acatttgtct gatagattgg taaagaagta tcatcacgta attctctaag ctgcgggata
     7981 taatctctca aagacacatc ctcggttgac gattcgcgaa taatgttccc ttgttcccaa
     8041 ataaacatca cgactaagat gatcaaacca atcagaacgg ctacaaaacc gcctcggaag
     8101 aatttgacaa cacttgagat aaagaaaacg acttctatcg caccgaagaa aaaggtaact
     8161 aaatatgcaa gccaacgaga atgcccattt tggataagat aaaagtaaag cagtgctgtt
     8221 gtcatcaaca tcgtcacagt gatcgataga ccgtaagcag cttccatatg atgagacgtt
     8281 cggaatgtga caaccactag agaacaggcg atccataaaa tcagattgac tgctgggata
     8341 tacatttgcc cgatactgtt cccaggatac atgatcttta accgaggcag cagtttcaac
     8401 ttgattgctt ctgaaactag cgtaaacgaa cctgtaatca atgcttgcga agcaatgact
     8461 gcagcgactg ttgcaaaagc aacgccgatc acgatccaac tttgaggcat catttggaag
     8521 aatggattca ggttcttgat ttgctgtgct tcagggtttt gataaacatt caacaaccac
     8581 gcagcctgcc caaaataatt gataaccaaa caaattttga cgtaaggcca gctcagacga
     8641 atatttcgtt tgccgacatg tccaagatcg gaataaagcg cctctgcacc tgtcgtagcc
     8701 aggaaaatat ttccaagaat gaacaagcct aatttgttat ctgcactaaa aagcagctgg
     8761 atagcataat aaggattcag tgcacggata actgtccagt cttgactgaa gttcattaat
     8821 cccattacgc ctaaaaaagt aaaccaagcg aacatgattg gtccgaatgc ttttccgaca
     8881 atatctgtac caaagcgttg gaccatgaat aaaacaaaaa taataactaa agtgataatg
     8941 acgatcacgt tctggttatt accgaaccgg tcaaaaaact gcggaattcc tcgcaagcct
     9001 tcaatcgcag tcgttaccgt cacagcaggg gtcaataccc catctgctag taaggcagct
     9061 cctccgatca ttgcaggaat gatcaaatat ttcccacctt ttcggacaag tgtgtagagt
     9121 gagaaaattc caccttcacc atggttatct gcattcaatg caatcacgac atatttgatt
     9181 gttgtcagta gagtcaatgt ccaaaaaatc aatgagactg atccgataac aaaatcagga
     9241 ttgattcctg acaatccgcc attatcttca acaatcgatt tcataacgta aagcggactt
     9301 gtcccgatgt ctccgtagac gactcccatc gctacaagca ggccagccat tgatatcttt
     9361 ttggtattgt gcgttgttgc cacgtttttc cctcatttct tgttatatgg atatccttta
     9421 ggtaagcttg aatgatagat gatattctta tccatgacac ccgctttcct aaattgcttc
     9481 taattatcca agtaacacac tgaagtgtca acttatttga ataaaattat tctttctttg
     9541 gacgttctct gatacgtctt gccacaaatg aataaagagc aaggcaaaaa attgcaccca
     9601 ataatgctgg tatcaaataa aaaccgccga gttccggtcc cagtggtcct agtaaaaatt
     9661 cgccgagcca actacctaaa aaaccgataa tgatatttcc agatacgcct cccgggactt
     9721 cctttcctaa aattgcgcca gctatcaaac ctaatatacc gccgataaat aacgaccata
     9781 aaaaattcag catctccttt ccctccttta tccatatttc tcacttttat tttacgcttt
     9841 attcagaagg actccaaaaa tatgcgccaa gaaactccag aaaaaaagaa gttgtaacaa
     9901 aagtgttcag cttatttccg tagaagctgc ttctggaaca ccgtgaatca gaggttgtga
     9961 aatcagcggt ttgacctgag tattagagaa acaaacggaa aaatagttcc tcatattttg
    10021 ccgttttttg agctaatatc gagggacagc tgattgaaca tcgtttattg gagaggttgt
    10081 aaaaaagctg ttctgcatca agtaataaga acagccaagt aaaaacagct cctaatgttt
    10141 ttaacttggc tggacttatt accgcagatg caagcttttg aacaccgttt attcgaaaaa
    10201 aaaggactgt gacacggctt ttgtcacagt cccctttttt cgaataatta ttgtccccct
    10261 gtcaccttca cgatcacaag tacattattc ctatgaatta aattattttt cttcattttt
    10321 cgttgaacca tcttcgttca acattgcttt tcttgacaga tttacgcgtc cttgtttatc
    10381 gatttcagtt actttcacaa ggatctcatc acctagttta acaacatctt cgactttatt
    10441 gacacgatcg tttgctaatt gggaaatatg gacaagtcca tcttttcctt tgatcaagtt
    10501 gacgaatgca ccgaattttt cgatacggac aactttccct agataaactt caccaacttt
    10561 gacttctttg gtcaaatctt cgatgatctt gatagctttt ttgatcattt ctgcatcagc
    10621 tgaagcaata cttacttttc catcttgatc gatatcgatt ttcacaccag tttcatcgat
    10681 gattccgttg atcgtatcgc cgcctttacc gataacatct ttgattttag caggttcgat
    10741 ctggatcatt tcgatttttg gtgcatattg gcttaattct tcacgtggag cagcaatcgt
    10801 tgaagtcaat tcttctaaga tttccatacg tgcttgtttt gcttgagtta atgcttcagt
    10861 taggatttgt tctgtgattc cttgaatctt gatatccatc tgtaaagcag tgataccatc
    10921 ttttgtaccg gcaactttaa agtccatatc gccaagatga tcttccagcc cttggatatc
    10981 agttaggatc gtatagtttt caccatcaga aacaagtccc atcgcaatac cggcgactgg
    11041 cgctttgatt ggtacacctg catccatcaa tgctaatgtg ccagcacaga tacttgcttg
    11101 ggaagaagaa ccatttgatt ccaatacttc tgctactaaa cggatcgtat aaggaaattc
    11161 ttcttctgaa gggattactt gtgctaacgc acgttcacct aatgcgccat gtccgatttc
    11221 ccgacgccct ggagagcctg cacgtcctgt agaaccaaca gaaaattgag ggaaattgta
    11281 gtggtggatg aatcgtttgc tgacttccac ccctaaacca tcaatgattt ggtgctctcc
    11341 tagaggtgcg agtgtacaag ctgataaagc ttgtgtttgt cctcgtgtga acaaacctga
    11401 tccatgtaca cgtggcaata agctgacctc tgatgacaat ggacggattt catccaattt
    11461 acgcccgtca ggacggatct tatcgatggt gatcaattca cgtacgacat ctttttcaag
    11521 atcttctgtg atttgtttaa cttctttcaa caagtgatct tcatcttcat gacctgcaaa
    11581 tttctcagca taagcttcgc ggatatcgat cttcacctgc tcgatattat cttcgcgagc
    11641 aagtttttct tcagtcatta ctgctgcttt cattgtagcg taagaagcat caaagatttc
    11701 ttttttcaat acttcatcaa cttgcagtaa agtcacttcc attttttctt tccctactgc
    11761 ttgaacgatt tcttcttgga aagcaactaa ctctttgata gcgtcaaaac caaacagcaa
    11821 tgcaccaagc atgtcttctt ctgaaacttc tttcgcgccg ctttcaacca tattgatggc
    11881 ttgtttcgtt ccggcaacag tcaattcgat atctgtttgt tctgcttgtt ctactgttgg
    11941 attcaagacg tactcgccat ttacacgacc aacttctacg cctgcgattg ggccgtcaaa
    12001 tgggatatct gagattgata gtgctaaaga agaacctagc attgctgcca tagctggcga
    12061 gcagtctgtt tctacactca tcacgatgtt cgttacttgg acttcattac ggaagccttc
    12121 tgcaaacatc gggcgaattg gacggtcgat caaacgggca gtcaatgttg cttccgtact
    12181 tggacggcct tctcgtttga tgaaacctcc agggattttc cctgctgcat acattttttc
    12241 ttcataattg atcgttaatg ggaaaaagtc tgtatctttt gcttctttag aggccacagc
    12301 tgcacttaag actactgtat ctccataacg gactaaaacg gctccgtttg cttgttttgc
    12361 tagctgaccg acttcgattt gtaagggacg gccgccccat gtcgttttga atacttgttt
    12421 ttctgacata acttctcctt ttccttctcg tgaaagcaag acgctactaa acaaatgaaa
    12481 actgccgaaa gccgtctttt gagcagcttt catttggtta gtaggagtcc atctagcttg
    12541 atcacggaat tttacttaat tgatatacga gtaaaaaaag tgagattcat gtgaatccca
    12601 ctctttttga ctaaaattaa cgacgcaagc ctaaacgttt gatcaattcg cggtaacgtt
    12661 gaacgtcagt tttacgtaag taagctaaca agttacggcg gtgaccaact tttttcatta
    12721 ggccgcggta tgaatgatgg tcttttttgt gcacgcgtgc atgttcattc aagtggttga
    12781 tttcttcagt taatacagcg atttgtactt ctggagaacc agtatcccct tcatggcgag
    12841 cgtattcgtt gatgatttca ttcttgcgtt cttttgaaat tgccatttct ttcacctctt
    12901 tcgattattc ccctgcgact gagtaaaacg ttggtgattc gcttaaccaa gtggcaggtc
    12961 atgtgcctag agcacacagc tatactttac ctgaaaccgg gttgaaaatc aagtagttaa
    13021 tcattaagaa aaggtagttt tcaaacaatc ttactactac ttttccattt ttgtggtaaa
    13081 ctataatgcg aaaatagact tgaaacacag tcttttaaga aaggggtaca tattccatga
    13141 ttacaatgga tgatatcatt cgtgaaggaa atccgacctt acgcgaagtt gcaaaagaag
    13201 tttctcttcc attaagcgaa gaagatatct ctttaggaaa agagatgctt gagttcttaa
    13261 aaaacagcca agatccaatc aaagctgaag aactacactt acgaggcggt gttggcttag
    13321 ctgctcctca attagatatt tctaaaagaa tcattgctgt tcacgtacca agtcctgacc
    13381 cagaggcaga tggaccttct ctaagtactg ttatgtataa tcctaaaatt ttgagccatt
    13441 ctgttcaaga tgcttgttta ggggaaggtg aaggctgttt atctgttgat cgagaagtac
    13501 caggatatgt tgttcgccat gccaaaatca ctgtgtctta ttatgatatg aatggtgaaa
    13561 aacacaagat tcgtttgaag aattatgaat cgatcgtcgt tcaacatgaa atcgaccata
    13621 tcaacggtgt gatgttctat gaccacatca acgatcaaaa tccatttgca ctaaaagaag
    13681 gcgtattggt gatcgagtag agaattggca ggttccttcg atactatgct acaagaaagc
    13741 tttataaaaa aggggagtgc tcaaaagctg cacttccctt ttttatgttt ctccactaat
    13801 cgaaatttag atagacatct agaaatcgca attccaaaaa attctgtgta ttggatacgc
    13861 atcttttctt attttttctt atttcttcca tatgggtgtt tatctcagag atgatagaat
    13921 agtttctagg ataaaaagta gcagctacga tgttatcctt cgtagaggat tcctgcttca
    13981 gctagttttt gtttgatgtt tttcagcata tgcttttctg ggtagcggat cgtatgcaga
    14041 tggatgccgc ctgttaattc ggataacaaa gtagcattac ttttttgata acgtctcata
    14101 aaggaatcga tatcttgtgg cgttttgatg tgcaaagttc ctgctaactc accgtaaagg
    14161 ggatgttcca caattacatc aatgatttca ccaccatttt caacgattag tctcagttct
    14221 tcttctgttt gatcttttcc atgctggaca gcgattttac tgatgtgccc agtattggtt
    14281 tcttctgttt cgaggatata acctcttgct gttgccacga tacttttacc tgcagctcgt
    14341 agtaaagcaa tatcgcctac aatgatctga cggctgactc caaaagtttt cgcaaacttg
    14401 ctagcactca ctggtttttc tgtatttgcc aaggtttgca tgatttgttt tcgccgtgtc
    14461 tctccttcga tcacacttat tcctccttca ttttgttttg gtattcgcgc gagtgtttca
    14521 tcaaatcaac atacgtgtct gttattgttt ccttatatcc cttatttttc agcagactaa
    14581 caactttatc caatacttgc tgctctcttt ttgcatcata aactgcttgg ttttcttctt
    14641 ttttcacttg tcctatttta gttaccgtat ccattctttt ttctaataaa gcaaccaact
    14701 ctcgatcgat catatcgatc ttatgacgta atgtttcaag agactcttct gttagttctt
    14761 cctctactgt cttgatgata cgagcaggat ttcctgcaat cactacattg tcgggaaaag
    14821 atttggtcac aaccgaacct gcgccgacta ctacgttgtc ccctagagtg acacccggcg
    14881 tgacgataac tcctccgcct aaccaaacat tattaccgat tttaatgggt tttgcgtact
    14941 ccagaccgct gttacgtttc actggatgta gtggatgcgt cgccgtgtaa agctggacat
    15001 tcggagcgaa catgcagtta tcaccgattt caatcgtgct gacatctaaa aatgtacaat
    15061 tgaaatttgc ataaaaattc tccccaacaa atatattata tccgtaatca aaattgataa
    15121 ctggctccat atagattttt ttccctgtac ggccaaaagt ctctttcaac aattgggatc
    15181 gcagttccgc tgattctgct tggttgatga tttggctttg acttcttgca aacatacggt
    15241 cggcaaccag ctcaggatca ttggcaaaat aaagctcgcc tgcaatcatt ttttcttttt
    15301 cggttttgaa ttcagtcata atctgctcct aattcttgta tttttttgaa aacaaccgct
    15361 ccgtcttctt gaataaacgt ataaggctcc gctaaataaa caggcgtttg attgattact
    15421 aagattttgg ctgacggctg gcgaaactgt accagatcac aaaacggatg aacttgaaaa
    15481 ctcgttccaa caatgacgat cagctctgct tggctgacgg cataagccgc ctgctccatg
    15541 actccatctt gaaacccttc accatataac acgatgtctg ggcgtatttg tcctccgcat
    15601 gcttgatgtt tgtcgctgtg aagatattct ttccagtcta ccgtttgttg acattttcga
    15661 caatgacatt gatacagact cccatgaaaa ttgacgagtt gcgggctttt agcctttgcg
    15721 tgcaaaccgt cgatgttttg ggaaacaacc caaacatttt tttctttcgc tagatgtgct
    15781 atttccaaat gaatgatatt gggttttgct tcaggatgat aaatcttttt gacaaattga
    15841 tagaatttat ccggttcatt caccattgct tgatgactca gcaagtattc cggctgctcc
    15901 atcccgtggt agattcctga caaagatcga tagtctggca ctccagaagg tgtggatacc
    15961 cctgcaccgg tcaaaaatgt aatttgctga taagctaata tctcttttgc tgcttcgtct
    16021 actgttaatt gtttcatgtt ttgtcacctc actttccatt atagcccata ctcgaacaaa
    16081 tttattgttg aaaagtcaga aaaatgggaa taaaaaagtg ttatgggcat ttgagcaatt
    16141 tatcacaatg ttcactgaca aaagaatgaa aacgtgttac aatactgctg tataaaagtg
    16201 aggtgaatcg atatgttacc attctttatt tattggggcg ttattctggc ttgtatcgcc
    16261 tggttagcgt taagcgttta tttctctgtt ttttatcttg tacgcaaaga aaatggaaat
    16321 ctttgggctt ttgctttatt caacgtgatt gccgcaattg ttttagccat tacattagcc
    16381 gtatatcgaa catggggctg gggaatcacc caatactcaa gtttgattta tctaatatta
    16441 gccatttatg gcgtcgttgt tcttttgcaa gcgatcctag gacgtgagcc aaagaaagcg
    16501 gcagcttaaa tgatcgagat ggaactggac acaggaaatt ttctgttcta gttctttttt
    16561 tattgtatta catacatttt tgtgtataat tatactatcg tttgcaatgg atagatgatt
    16621 cacattttga ttgttttttc ggtaaaagta aagatttcta tatttatcag tattttttca
    16681 aaaaccagca gttatagatt gacaaagcct ctcgagtatc gtaaactttt tttgtataaa
    16741 taactgaata cgagatgcct caatcaatga ggtagaggtc gcgagaatca ttaaccctgt
    16801 ggagtgaagc aaacatggag aagcaggaat agggaggatc gccgaaatgt gcactttttt
    16861 gcttggagtg tatgttggga cgcaagttaa gagcttgcgg actgtcttag cagtgatgct
    16921 aagttgcgct atgttttgtg agaggtttat caccttatgg aattttagcg gcctttttat
    16981 atctataaat cggtcgcttt ttattttttc agataaagct ttaccgcatt tcatctagac
    17041 cgctcgtgta tcatataatc agaaagggag aaaaaaatga aaaaaaatat ggtttcagtt
    17101 gccgtactat ttgcttttgt cttctcacta ttcagtgtgg gatctctggc aaatgcagat
    17161 gaaaaaacac cgagcgatga gtttcgcgta ggtatggagg ctgggtatgc acccttcaac
    17221 tggtctcaac aaacagatga gaataatgcc ttgccaattc aaggccaaaa tagttacgcc
    17281 ggcggttatg atgttcaaat cgctaaaaaa gtagcagatg gtttagggaa aaaattagtc
    17341 atcgtccaaa cgaaatggga tggtctggct cctgcccttc aatcaggcaa gatcgacgcg
    17401 atcatcgccg gaatgagccc tactgctgaa cgacgaaaag aaattgattt taccgatcct
    17461 tattacgaat cacaattagt agtagtagtt caaaaagata gcaaatatgc aaaagcaaaa
    17521 agtttagcag atctttctgg agcaaagatc actgctcagt taaatacatt ccactatact
    17581 gtgatcgatc agataccaga tgtgcagaaa caacaagcaa tggataattt ctcagcaatg
    17641 agaacagctt tagcttctgg aatgatcgat ggttatgtca gcgaacgtcc ggaaggtgta
    17701 acggcaacta gtgtgaacaa agacttggaa atgcttgaat tcagcggtgc agatggcttc
    17761 cagacaaacc cggaagatgt tcagatttct gttggtatgc gtaaaggcga cccggatatc
    17821 caaaaagtaa accagattct ttctggcatc tctaacgatg aacgaaccaa aattatggac
    17881 caagcagtca aagatcagcc tgctgcaact gatagtgaag aaaaacctgg catcatttct
    17941 gatttcacta cgatttggaa acaatacggc aatatgttct tacgaggtgc tggacttacc
    18001 ttgttcatcg cattgatcgg gacagttgtc ggtactacac ttggattact gattggtgtc
    18061 ttccgttcgg tacctgaatc aggaaatgca ctgactcgct tcttccaaaa aatcggaaat
    18121 gcacttcttt ctatctatgt cgaagtattc cgcggaacac cgatgatggt acaagcaatg
    18181 gtcatcttct acggtctggc actcgctttt ggcatttcat tgaaccgaac gattgccgct
    18241 ttgtttattg tctctctcaa tactggagct tacatgacag agatcgttcg tggggggatt
    18301 tttgcagtag atgaagggca gttcgaagct gcgcaagcca ttggtatgac ccatggccaa
    18361 acgatgagaa aagttgttat tccacaagtt ttacggaata tcttgccagc aacaggaaat
    18421 gagtttgtta tcaatatcaa agatacagca gttttaagtg taatcggcgt agctgatttg
    18481 ttcttccaag gaaactctgc ttccggtgcg aatttccaat tcttccaaac atttacgatc
    18541 gtcgggatca tctacttagt catgaccttt acgatcacca gaatcctgcg ggcggtagaa
    18601 aagaaaatcg atggtccttc agcttatacc aagcttgaag aaatcgacaa ttcaaatttg
    18661 caggaataag gaggaagaat catgaatgaa aaaattattg aaatcaaaca tctaagaaaa
    18721 agcttcggtg aaaatgaagt attgaaagat atcagcgtaa cagtcaataa aggtgaagtt
    18781 gtgacgatca tcggttcttc cggttctggt aaatctactt tcttgcgctg tatcaattta
    18841 ctggaaaaac caacaggcgg cgagatcatt tataatggag aaaatgtatt agctcctaaa
    18901 tataatttac ctaaatatcg aacgaatcta ggtatggttt tccaatcctt caacctgttc
    18961 aacaatatga atgtcttgga aaactgtatg tctggtcaaa caactgtcct gaaacgagat
    19021 aaagaaactg ccaaaaaagt agcaatcgaa aatctggaaa aagttggtat ggatcgttat
    19081 atcgaagcca aaccagcaca attatctggt ggacagaaac agcgtgtcgc aattgctcgg
    19141 gcattatcaa tgaatccaga tgtattgcta ttcgacgaac ctacttcggc gttagaccct
    19201 gaaatggttg gcgaagtgct taatacgatc aaagacttag cacatactgg cttgacaatg
    19261 cttatcgtga cgcatgagat ggaatttgca aaagatgtat ctgaccgtgt catttttatg
    19321 gataaaggtg tgattgcaga agaaggtaca ccagaagata tctttgtcca tccgaaagaa
    19381 gaacgtacaa aagaattcct ttcacgtatt ttaaatgctt aggatcaata gctgattggg
    19441 acaaagagct gcggtgttta ccgcagttct tttttatgaa ttactcataa aaggtaaatt
    19501 tctgaaaatt ttggaatctt agttgtgttt ttcagaaaac tctcttaata tggaagtaat
    19561 taaacttttt tagttaggat gatttaaaaa tgaatgaaga gcaagaactg cagcgtggac
    19621 tgaaaaatag acatgtccaa ctgatttcta ttggcggagc gattggaacg gggttgtttt
    19681 taggttccgg aaagtctatc cagctagctg gcccttcgat attgctcgcc tatcttatta
    19741 ctggatgcat ctgttttttc attatgcgtg cgttaggcga acttctgtta tcaaacacca
    19801 ataaccattc ttttctggat tttgttgcag aatatcttgg caaaaaagcg gctttcatca
    19861 ctggctggac gtattggttc tgctgggtat cgattgcaat ggccgattta acagccatcg
    19921 gaatgtatgt acgctactgg gcgcctggtg ttcctcagtg gcttcctgaa ctgattgcat
    19981 taggtcttct tctttgcttg aatatggtgg ctgtctcatt gtttggtgag ttagagtttt
    20041 ggtttgcatt gatcaaagtt gtagcgatca ttgcctttat cctcgtagga gcttatatga
    20101 tcctcaccca ctatacgaca gatattggca cagccagtat cacgaatcta tggtctcatg
    20161 gcggattctt tccaactggt gcaaaaggat ttatcttagc tttccaaatg gtaacctttg
    20221 cttttgctgg gatagaatta gttggattag tcgctggaga aacagaaaat cctgaaaaag
    20281 tgttgccgga agctatcaat aatattccta tcaggatcat cttattttac ttaggatctc
    20341 tttttgtcat tatggcaatc tatccatgga acagcttgaa tccagataac agtccatttg
    20401 tagaagtatt ttcggaaatt gggatcacga ttgctgcttc cttgatcaat ttagtcgtat
    20461 taagtgcagc agcttctgcc tgcaacagtg caatatatag tacaggacgt atgcttcgtt
    20521 ctttagcgca agaaggcagt gcccctaaaa aattcaaaaa gttaacaaca catcatgtgc
    20581 cagggaatgc tttgacattt tctactatcg tcattttcat ttctgttatc ttgaattacg
    20641 tgatgcctag tgaagtattc acactagtaa gcagtattgc cactacttgt ttcttgttta
    20701 tctggagtat gcttgtctac acgcacatga aatatcgtaa aagtatcctc ggcaaaaaag
    20761 ctcattcatt taaaatgccg ttgtacccat ttagtaatta tctggtattt ctttacatgg
    20821 cctttgtgtg tgtcgtcttg ttcctaggaa aagatacgag aatcgcttta ttactaacac
    20881 ctgtgtggtt cttgcttcta ttactaatct atcatatgaa atatgaacgt aagaagtaag
    20941 aaagtagttg tgacagaagt ggtcagcttc gagaaataag aaggaattta cgaaaattgc
    21001 ttcttaaatt tttgtgaaat ttcggcttat ttcttggaga taaaagcttc tgtcccagcc
    21061 tcttttctat ttccccggaa acaaccgctg ataataggca tctgcttttt tataggaaaa
    21121 aatccaaata ccagatacaa aaaaacgtcc gaataacccg atcaacggta caaaaaagac
    21181 accggcaatc aagcataagt taatcatcat ggagataaga cttcgacggt cctttgacaa
    21241 aactctcacg acatgggaat ctggtttatt tgctttcatg atttgcctca tcaagatacc
    21301 aaaagaaaaa ctccacatcg tgtatactaa gacataagcc atctcaggcc aaaaagcttc
    21361 agggttacgc ccgacccaac tagtaacaga aggacataaa gtcagccaaa agagcaaaaa
    21421 gatattcgac cagaccactc ggtaattaat tcgttctgcc atctgaaata tacgatgatg
    21481 gttcacccag atcaccgcaa caaatataaa gctgatggta taagctaata atgtatttcg
    21541 gatgacccat aaagaatgaa agctagatgt attagggatc ttgatctcta atacaataac
    21601 tctcaaaaca atggctacca ctccatcagt aaatgcttct aatctcgact ttgtcacgat
    21661 gattcctcct cagatgattc agcgctttta ttttatcact tacgttatta aataaccatc
    21721 gttttatata gggaattttc tgaaaattgt tgcatatttt tcgaaatttt gttactttta
    21781 aaaaaaccgt aaaggagtta tgtatgacaa aaaaattatc atttaaagac tatcttttta
    21841 taggctccat gcttttcggt ctattttttg gtgctggaaa tcttatcttt cccgttcatt
    21901 tgggtcaaga agcaggcgct gctacctttt gggcgaatct aggtttcttg gttaccggta
    21961 tcggtcttcc cttcttaggg gtgattgcca ttggtgtatc gaaaagctca ggtgtatatg
    22021 aattagcaaa acggataaat caaacatatg cgatggtttt taccatcttg ctttacttag
    22081 ttatcggacc gttttttgct ttacctcgcc ttgcaaccac atctttcgag attggtttag
    22141 caccatttat cgatcctagc agacagacgc tatatctagc aattttcagt attgtatttt
    22201 ttgtgctggc ttggtggttt tcaagaaaac cgacaaagat attagattat gttggaaagt
    22261 tcctgaatcc tgcatttttg gttttattag gtgctttgct tctccttgct tttttgaatc
    22321 cactaggttc tgtaaatcaa gcgcctattc agccaaatta tcaagagcat gcttttttca
    22381 cagggtttac tcaaggatat aacacattag atgcgcttgc tgctttagca tttgggatca
    22441 tcattgtcac aacaatccaa aacatgggtg taacaaaacc tgctgaaatc gctaaagaca
    22501 cgatcaaatc tggtgcgatc agcattatat tgatgggaat catttatact ttgctcgctt
    22561 atttaggtgc tatgagctta ggtagctttg ctctaagtga aaatggcggg atcacgctgg
    22621 ctcagattgc tgatcattat ttaggtactt atggcagtat cttattagca tttatcgtta
    22681 tattagcttg cttgaagacc ggtattggtt tgattacagc ttttgcagaa acattcacag
    22741 atttgtttcc gcaaagaaat tacgcattct ttgttgcact tgctagtatc cttccttgtt
    22801 tagcggcaaa cgtaggcttg acgaatatca ttcaattttc gttgcctgtt ttgatgttca
    22861 tctatccatt agcaatgaca ctgattttac tagtgttagt tggtcctttg tttaagcagc
    22921 gtacggctgt ttatcgaatg actacttatt ttacattgat tgcttcgatt tttgatgggt
    22981 tgaacgcttg cccagaaact atcaaacaaa cacctattgt tcaaaatctt ttatatgttg
    23041 cggaaagcta cttgccgttt ttcaaattgg ggatggggtg gatcgtacca gcagttatcg
    23101 gttttgttat cggactgatt tggagtttcg ctaagaaaga agaagtagca gattgataaa
    23161 agaggttgtg aaagagacgt tcagccttga gcaataaaaa gtaattttga aaaatggctt
    23221 ctcacatttt tgcataaatt tgacttaata ccgagaaact gacttttgaa caccgtttat
    23281 tgagaggtcg tgaaaaagcc gcttagtttc aagtattaag aaatattttg tgaaaatggc
    23341 ttctcacatt tttgcataaa tttgacttaa taccgagaaa ctggcttttg aacaccgttt
    23401 attgagcgtc tataaactga cctgagtatt agagaaacaa aacggcaaag tagctccata
    23461 tactttgccg ttttgttttg aactaatacc gaagagaagc tgatcaaaca acatttcttt
    23521 tataatatag attttagaca tatatatgat ataaaaatag ttttcgcaaa a
//
LOCUS       DACDAF010000043        23120 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.043, whole genome shotgun sequence.
ACCESSION   DACDAF010000043 DACDAF010000000
VERSION     DACDAF010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23120)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23120)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23120
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.043"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(34..315)
                     /locus_tag="IVZ69_001534"
     CDS             complement(34..315)
                     /locus_tag="IVZ69_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8183622.1"
                     /translation="MKSEIQVILPSDLDQELRRYFYRVAKEAVDQVRIETSLSKEVFR
                     LGEACKYLSCSRSTLKKFIREKGLKVSIIGDCQFIRKEELARFIKEYEV"
     gene            complement(366..572)
                     /locus_tag="IVZ69_001535"
     CDS             complement(366..572)
                     /locus_tag="IVZ69_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8183623.1"
                     /translation="MKPKDFRKFCGLSQSELAEKYGISVQAVRNKESGKTNYSPEEMI
                     ILKYLVKEKGIENITIDQIFFNEK"
     gene            736..1467
                     /locus_tag="IVZ69_001536"
     CDS             736..1467
                     /locus_tag="IVZ69_001536"
                     /inference="COORDINATES: protein motif:HMM:NF024252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8183624.1"
                     /translation="MFDKNINSEIGKRIQEIRVSLGYTLEEFGENLTPPASKSNVSRW
                     EKGKNIPNKARLLSIAKLGGVSTEYLLTGNSQKTKKYIKYLFNEIFFDNGTFHNKFKD
                     FGKDRDRLGLYDLFLAVSKTYSLDKSPSLKDNFVEMIIDDVYKKLLQTDKSDDQLILG
                     FIYICLDEKLSNRQKSLKSINYEVFNYLGVAFGLIDSEIKSTNAGNDEDLLNYLKELT
                     SFIDEIKTTTFNKKKYFQNQYDIEE"
     gene            1521..2666
                     /locus_tag="IVZ69_001537"
     CDS             1521..2666
                     /locus_tag="IVZ69_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP8183625.1"
                     /translation="MATIKQYEKKDGTKAWMFQTYLGISPLTGKEVRTTRRNFKTKKE
                     AQIELNRLLVDFEENGLKRETNETFQEVYDLWYESYKTTVKEVTQLKIEIKFNKWILP
                     KYGQFRIKEITTKHVQKILNQWAKTTDQYKVLHSTVSRIFKYAMTLGLITKNPCELVI
                     MPNRNVEKKKDTVKIYSRDQLETLFQYLESKRSTYRAEYDKTLLRFLFFSGCRISEAL
                     ALDWSDIDFDSNTVTINKTLSQTKYGYKISSPKTRNSYGSLSLDNKTINWLKKWQINQ
                     KRYMLTLGITDPTMIFCGIYKEIITKHAIYSRMITICKNSGIPFLGNHVTRHTHASML
                     LESGVSMKEVQERLRHSSIKLTMDTYAHLTKETKEKTVEKLAEHLNF"
     gene            complement(2751..3056)
                     /locus_tag="IVZ69_001538"
     CDS             complement(2751..3056)
                     /locus_tag="IVZ69_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HAP8183626.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(3081..3512)
                     /gene="ruvX"
                     /locus_tag="IVZ69_001539"
     CDS             complement(3081..3512)
                     /gene="ruvX"
                     /locus_tag="IVZ69_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HAP8183627.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            complement(3509..3775)
                     /locus_tag="IVZ69_001540"
     CDS             complement(3509..3775)
                     /locus_tag="IVZ69_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HAP8183628.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            complement(4030..4755)
                     /locus_tag="IVZ69_001541"
     CDS             complement(4030..4755)
                     /locus_tag="IVZ69_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HAP8183629.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            complement(5116..5186)
                     /locus_tag="IVZ69_001542"
     tRNA            complement(5116..5186)
                     /locus_tag="IVZ69_001542"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5152..5154),aa:Gly,seq:ccc)
     gene            5303..6055
                     /locus_tag="IVZ69_001543"
     CDS             5303..6055
                     /locus_tag="IVZ69_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HAP8183630.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            6071..6550
                     /locus_tag="IVZ69_001544"
     CDS             6071..6550
                     /locus_tag="IVZ69_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HAP8183631.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(6801..8381)
                     /locus_tag="IVZ69_001545"
     CDS             complement(6801..8381)
                     /locus_tag="IVZ69_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HAP8183632.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(8374..9117)
                     /locus_tag="IVZ69_001546"
     CDS             complement(8374..9117)
                     /locus_tag="IVZ69_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183633.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            complement(9293..10069)
                     /locus_tag="IVZ69_001547"
     CDS             complement(9293..10069)
                     /locus_tag="IVZ69_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8183634.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            complement(10317..11153)
                     /locus_tag="IVZ69_001548"
     CDS             complement(10317..11153)
                     /locus_tag="IVZ69_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HAP8183635.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            complement(11164..12093)
                     /locus_tag="IVZ69_001549"
     CDS             complement(11164..12093)
                     /locus_tag="IVZ69_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HAP8183636.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            12285..12638
                     /locus_tag="IVZ69_001550"
     CDS             12285..12638
                     /locus_tag="IVZ69_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HAP8183637.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            complement(12712..13368)
                     /locus_tag="IVZ69_001551"
     CDS             complement(12712..13368)
                     /locus_tag="IVZ69_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP8183638.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            13594..15528
                     /locus_tag="IVZ69_001552"
     CDS             13594..15528
                     /locus_tag="IVZ69_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP8183639.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            complement(15614..16837)
                     /locus_tag="IVZ69_001553"
     CDS             complement(15614..16837)
                     /locus_tag="IVZ69_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="HAP8183640.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(16831..18729)
                     /locus_tag="IVZ69_001554"
     CDS             complement(16831..18729)
                     /locus_tag="IVZ69_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HAP8183641.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            complement(18723..19841)
                     /locus_tag="IVZ69_001555"
     CDS             complement(18723..19841)
                     /locus_tag="IVZ69_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase family 88"
                     /protein_id="HAP8183642.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            complement(19924..20757)
                     /locus_tag="IVZ69_001556"
     CDS             complement(19924..20757)
                     /locus_tag="IVZ69_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8183643.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            complement(20750..21667)
                     /locus_tag="IVZ69_001557"
     CDS             complement(20750..21667)
                     /locus_tag="IVZ69_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8183644.1"
                     /translation="MIQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            complement(21690..21869)
                     /locus_tag="IVZ69_001558"
     CDS             complement(21690..21869)
                     /locus_tag="IVZ69_001558"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183645.1"
                     /translation="MNKINENTSNTVLPATYSDATSYLTTAAYNYWQTGDFENSYLKE
                     AENFAHKYGVKLTGD"
     gene            complement(21894..23018)
                     /locus_tag="IVZ69_001559"
     CDS             complement(21894..23018)
                     /locus_tag="IVZ69_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP8183646.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
BASE COUNT         7305 a         4533 c         3789 g         7493 t
ORIGIN      
        1 cttttttcta tcaaaagcac gccacgcaac tttttatact tcatattctt tgataaacct
       61 tgctaattct tcttttctaa taaattgaca atctccgatt atgcttactt ttaaaccttt
      121 ctctctgata aattttttta atgtacttct gctacagctt aaatacttac aagcttcccc
      181 caatctaaaa acttctttgc ttagagatgt ttcaattcga acttgatcta ctgcttcttt
      241 tgcaactcga tagaaatatc ttcgcaattc ttgatctaaa tccgatggaa gaataacttg
      301 aatctcagat ttcattttct ttgcccccac taatttgact acatgtattc aaattcaact
      361 tttcgtcact tttcattaaa aaaaatttga tcaattgtga tattttcaat tcctttttct
      421 ttcacaagat acttcaaaat aatcatttct tctggagaat agtttgtttt accgctttct
      481 ttgtttctta ccgcttgtac tgaaatgcca tatttttcag caagttcaga ttgtgataat
      541 ccacaaaact ttctaaaatc tttaggcttc atgactcctc actcctcctt cttttcaact
      601 tttcgtcact aaaagaataa catatattta ttcataccgc aacgtaaaat tcaactttta
      661 tctacttttt catttcatta tatgagaatg tagtgtaaac tgtagaatag aatagatgaa
      721 ggtggtgaaa ccattttgtt tgataaaaac attaattctg aaattggaaa acgaatacaa
      781 gaaatacgtg tttctttagg gtatactctt gaagaatttg gcgaaaatct gacacctccc
      841 gcaagcaaaa gcaatgtttc tagatgggaa aaaggaaaga acatacccaa caaagcgcgg
      901 ctactaagta ttgctaaact tggtggtgtt tctactgaat atctactgac aggtaattct
      961 caaaaaacta agaaatatat caagtattta ttcaatgaga ttttttttga caacggtacc
     1021 ttccataaca aattcaaaga tttcggtaaa gacagagata ggcttggtct atatgactta
     1081 tttttagcag tatcgaaaac atatagtcta gataaatcac cttctttaaa agataacttt
     1141 gtagaaatga ttatagatga tgtatataaa aaactcttgc aaactgataa atcagatgac
     1201 caactcatcc tgggtttcat atatatttgt cttgatgaaa aactttcaaa cagacagaaa
     1261 agtcttaaaa gtatcaatta tgaggtattc aattatttag gtgttgcatt tggtttaatt
     1321 gatagcgaaa tcaaatctac aaacgcaggt aacgatgaag atttattaaa ttatttaaaa
     1381 gaattaacat cttttattga tgaaataaaa acaactacat tcaacaaaaa aaaatatttt
     1441 caaaatcaat atgatataga agaataaaga ttacattttc ctatcaaaag cacgccacgc
     1501 aactgatagg aggaaaaaca atggcaacaa ttaaacaata tgaaaagaaa gacggaacca
     1561 aagcttggat gtttcaaaca taccttggaa tcagcccgct aactggtaaa gaagtccgta
     1621 ctacacgtag aaattttaaa acaaaaaaag aagctcaaat agagcttaat agactacttg
     1681 tagactttga agagaatgga cttaaaaggg aaacgaacga aactttccaa gaagtgtatg
     1741 atctctggta tgaaagctat aaaactactg taaaagaagt cactcaatta aaaattgaga
     1801 tcaagtttaa taaatggatt cttccaaaat atgggcagtt tagaattaaa gaaattacta
     1861 caaaacatgt tcagaagata ttgaatcagt gggctaaaac aacagatcaa tataaagtcc
     1921 tacattctac cgtaagccgt attttcaaat acgcaatgac tctagggctg atcactaaaa
     1981 atccctgtga gctcgtaatc atgcccaaca gaaatgttga aaaaaagaag gatactgtca
     2041 aaatttattc acgagatcaa ttagaaacct tatttcaata tttggaatcc aaaagaagta
     2101 cgtatagggc agagtacgat aaaactttac tgcgctttct attttttagt ggctgtcgaa
     2161 tcagtgaggc tttagcctta gactggtcag atattgactt tgattcaaac accgtcacta
     2221 taaacaaaac cttaagccaa acaaaatatg ggtacaaaat ttcaagtcca aaaacgagaa
     2281 atagctatgg ttccctatct ttagacaata aaaccattaa ttggctaaag aaatggcaaa
     2341 tcaatcaaaa aagatatatg ttaaccctcg ggattactga tccaacaatg attttttgtg
     2401 gaatctacaa agaaatcatt actaaacacg ctatctattc tcgtatgatc acaatctgca
     2461 agaattctgg tattccattt ctaggtaacc atgtaaccag acacactcat gctagtatgc
     2521 tgttagagtc gggagtctcc atgaaggaag ttcaagaacg ccttagacac tcatcaatca
     2581 aattaacaat ggatacctat gctcatctaa ctaaagaaac caaagaaaaa accgttgaaa
     2641 agcttgcaga gcacctaaat ttctagcgga acgtattcaa tcccgtattc aattcaaaac
     2701 aaaaaaaagc tgaaccctta tctaccaagg gttcagctat catttacagc ttattcttct
     2761 tcttccgcca tgaatgtatt gaatacttct tcaatcatgt cccattctgc gtctgtttcg
     2821 atttgttcta actcgccttc tgttccatct tcgttttcga tgtatgcata agcttgtaat
     2881 tctacatctt catcttctga aacaccagca ggatataaaa gaacatagtt acgtccaaat
     2941 tcttcttgtc cgtcaactgt tagtaggatt tcatataatg tttcatttcc ttggtcatcc
     3001 accaatgtga tgtgttcgtg tccttcatgg tcgtgggaat ggttatgttc tgtcataaga
     3061 ttacctcttt tcttttatta ttaaaataat tgcttacctg agccgtctaa ataattttgt
     3121 aagatcatca cagctgctaa tttatcgatg actttttttc gtttggctct tgaagtattt
     3181 gcctgctcta ctagcatacg ttctgcctga acagtggtta atcgttcatc ttgataatca
     3241 actggcaagg agaatagttc tttgatcttt tctccgtatg acatggaagc ttctgccctt
     3301 ggtccgatgg aattgttcat atttttaggt aatccaacta caaaccggtc tacttcatat
     3361 tgtgctacta attccttcaa ccgatcaaag ccaaactctt cttctgcttc attgatccga
     3421 atgatctcta ctccttgagc tgtccagcca aaggggtcac tgatagcaac acctactgtc
     3481 ttagaaccga catccaagcc cattactctc ataaattcac tccatgattt gagaggtagt
     3541 ccttgacaat tacttccatg atctcatcgc gttcgtgacg gcgaatcaaa tttcgagcat
     3601 cacgataacg aggaatgtag gccgggtctc cagaaagcaa gtagccgaca atctgattga
     3661 ttggattgta gcctttttct tccaaagccc gataaacaat cgctaatgtt tcgctcactt
     3721 cttttttgcg actatcgtca aaaccaaaac gtacggtttc atctgtaaaa cccatgattc
     3781 tacacctctt tcccgcaagg taattccagc ttaccttcta caaccttatt ttactcgaag
     3841 aaagggaaaa ctacaaacaa atattccaaa cttccgaata aattaagaaa cactatttgt
     3901 atgttttttt ccttttttct gtagctttat caaaagtact cttttcataa agtatacgct
     3961 atatttcttt gaatgtatgt ttttacacaa ttttttcata atattcataa aaaattcgaa
     4021 tagctgctac taattttttg tttttgttgc ttgtcctgtc tcataattga tcgtgtagcc
     4081 atcttgaaca ttgtagataa agacattgaa ttcaattttt ttgtcttcaa tgctttctgc
     4141 ttccaattgc actcccctgg ctaccagttc attcccctca aaatgaggag tgacacggta
     4201 gcgtacatga tgatttgttt ctttgatata tgccgcaata tcattttcgt gagcaagcat
     4261 gtatggagca ttcaacgaac gtgtccctgt catcaagttt ttaatgttgt tattttgacc
     4321 agtcagctgg aaaccaatta aatggctgcg attatataac cattgcccgt cacttaattt
     4381 cttttgtttc caacctgtcg ggtcaatata caaaggctct ctcttttcag tagggaacaa
     4441 atcttttcca agcatagcat tggcttgtcc tactctgttc aatttatcaa tatttgaata
     4501 gctttcccat gttcctttgg aaaggctaag atcctctttt gtaaattccg gctgattccc
     4561 attgatttct atttcttgat gttttccatc atattctggc acatccgcta cttgagaagc
     4621 ttgtggtgtg gaatcaaaaa tagttgtaat ctgctgaaag atatctgaat ctttttgtgt
     4681 ggtggaaaca ccgaatgccc ctgcaatcac agcagcgacg atccccacga tcgccttggt
     4741 tgtttttttg ctcatttctt tactccttta ctaacagctc cctaaatctt aacatatgtt
     4801 cccctataaa taaatactag aaagaaatag aaacagcaaa aaataaaacc tgttttaaga
     4861 tggcttaaaa atacaaaaaa gagacggatt cctcgtctct aatcagtcac cactctatct
     4921 gtaaggtatt tattattatt caaaaatttt cttcatactc aagacaatac actgatttca
     4981 caaccgcttg gtaaacggtg cgcaaaagct tgcatctgcg gtaataagtc catccaagtt
     5041 aaaaacataa gaagttgttt ttgcttggct gttcttatta cttgttgcag agcagctttt
     5101 tcacaaccta ttttaagcgg gtgacgggaa tcgaacccgc gacatcagct tgggaagctg
     5161 ggattttacc actaaactac acccgcaata caaaaacagt atacgcctct tttattcctt
     5221 cctcaagttt ttttattctt tacgcttctg gtatgttttg tagtaaaata aaactaatca
     5281 atcaattatt ggagaagatg ctatgacggg aaaagaatta gatctgttgc tggacacttg
     5341 tttactcgct gggaaaatca tgatggaaag caatgcggag atgtatcggg tagaagatac
     5401 gatgagtcga attgctttag cttctggaaa tttccgtttg gtcagctatg tcactcaaac
     5461 cggtctcttt attggtcttg atcgtacctc gaccatccga atggaacaaa ttaccaaccg
     5521 ttcgattaat ttagaaaaag tagtaaaagt aaatgatctt tcacgtaaat atgttgcttc
     5581 agagctaaca ttagaagaac tttactgcga actgcaagca atcgaccgag accgttcttt
     5641 ctttcctgtc tggttgcaaa tcgttagcgc ggcagtgatc agtggaacaa ttatggtgtt
     5701 atttggcgga aagatgaccg atttacctgt gactttagtc attggaggat tgggatacgc
     5761 agcttatcta tatagtttga aattttttag aatcaaattt ttatcggaat ttttatcttc
     5821 tttattgatt ggcatagccg ctatctacag cgtacgtttt ggcttaggaa gcaatcagga
     5881 tctaatcatt atcggatgtg tgatgccttt agttcctgga gttcaaatta cgaacgctat
     5941 ccgtgatttg ctagctggac attatgtctc aggagtttct cgcggaacag aagcgatgat
     6001 gactgctacg atgatcggtt ttgcgattgc ttttattttc cagctttttt attaggaaag
     6061 gaacacaagt atggggacga tatttattca gttttctttt agttttttag cgactgcggc
     6121 atttgccgtt attacaaatg tacctaggcg ttcattgatt tgttgtggtc tttctggtgc
     6181 ttttggctgg atgatctact ggatctgtgt tcaaataggc ggatctgctg cttttggttc
     6241 attgcttggt tctttaggag tagcattcat cagcgatctt ttctctaaac gtttgaaaat
     6301 gcccgtaacg attttcaata ttcccgggat ggttcctcta gtccctggtg gtttagctta
     6361 tcaagcggtt cgaaatctcg ttactgaatc ctatcgagaa gcggctcatt atgcggtcca
     6421 agcaattatg attgctggag caatcgcttt aggtcttgta ttatcagaag tctttaacca
     6481 taacatccgt aatttcaaag taaagcgtga cgcaatcatg atgaaacgaa aaaaacggct
     6541 ttttaaataa acgaagtgta acaaagaaaa ggttgtgaaa gagacgttca gccttgagcg
     6601 atgacaaaat atctcacaaa cattgcgaca agtaaccgca ggagcaataa gaagtaatta
     6661 tgagtattaa aaaaagtttt gtaaaaatag cttctcacat ttttacataa aattgactta
     6721 atactgagaa actgactttt gaacaccctc tatctgtaaa aaaggggctg cgacatgatt
     6781 tttgtcacgg cccctcttct ttattcaaat tttttccaaa acgttcgttg ataataaacg
     6841 atccatagag cggaaagtat tagaactaaa ccgatcacag gaatattcac taaccaaaat
     6901 ggataaaaca aagccaacat tccgtataag acgataagaa taatactgat gatcaatgaa
     6961 cccatcatag ttgcgactaa acccaaactt cctgaacctc tgttaaataa ttggttaata
     7021 ttggtccagt tcagcagcag caaccgataa tctctagcga aataacgtag tgacaataag
     7081 tagcagccga ataaagaacc aaatagcaag ctagggataa aaaacaaagg cagctgaaaa
     7141 gacagtccgc ttaataatgc gatcccacca gttaaaaaac tctgcaatat ccatccgaat
     7201 ctgaactttt cttttaaata ttggttcata gagattggca aagaacggat aaacagaaaa
     7261 ttttcttgat ccaaagaaat aagattgctg ataaaagaag tctgattaac tgttaagaaa
     7321 gccaatgcga tccctaccag gaaaacaaca ccgattaact tattatctaa atcagttaat
     7381 tttatttcgc ctcctagggc aaaagcaaga ataaaaatga ttggagttaa caaggaagaa
     7441 gaaagaactt gcataatcaa attaggttct tttactaatt gagcattgta actaaataaa
     7501 agctgatgca cattttggtt ctttttatgg gttcttttta ttttgaactc actgtttgaa
     7561 tcagtcagtt gctctgtaag ctttggtact atcagctgtt ttacagcaag gaaaaatccc
     7621 agagccgtga tagctagtat tccccaaccc aataaacctt gttgagaaag tggctgactg
     7681 gcagcatcat agaatggcaa taatatcgaa atcggatgcc gatctgttaa ctcattttca
     7741 atagtccccg tttgatgatt catccacatg attccagcaa atgcgatcag catcgagctg
     7801 ccaagcaaga tactagaaac tgtttttcta tgttttttaa acactgctgt tcgagccaaa
     7861 ccaaaaacaa tcaaactagc cagacaaaaa agaataatca aaaatagaga aaacaaaagg
     7921 attgagataa tgatagtaag caaaatccct agatcagctc gccatccggt taaaataaac
     7981 atgactagaa gcggaaaaac aaaaggaatg atggtcaaag caactaccaa aatctttgct
     8041 gaaaaaacct gttcttgtcc aaaaggcaga ggcaaaaata cttgcaggtc atttccttca
     8101 aaaaagatat tataaatgac tgatatactt tgagttaaac ctaacatacc aaaaagtgcc
     8161 acgtaataag taaagaaacc tggcaattta acaaagttca tagcaaacat agcaaatccg
     8221 taaatcagta aaaaaatcag ccctgaaaaa agattttgag acaaaagata gatagttaat
     8281 cgctttccct tttttccttt ctctcttgct ttattcgtga gctgtggatt aacatataaa
     8341 agattaactc gaattaattc taataattgt cgcttataca tacggtccat ctcctgtcgc
     8401 ttgccttcca gccattttca aataaatctt ttctagcgtt tcatcaggtg agccattcaa
     8461 taattcacta actgccccct gataaatcaa ttcacctttc ttcaaaatag ccagtttatc
     8521 gcataactgt tgtgcggtat ccaatacatg tgtagaaaaa atgactgttt ttccttttgc
     8581 ggcatgagcc ttcatcattt ctttcaaatc aaatgctgct tgaggatcaa gtccttgcaa
     8641 aggttcatcc aatacccaaa tatctggatc tggcagcaac gtgccgatca aaatcgtttt
     8701 ttgacgcatt ccatgtgaaa aacttgcgat tgtttcattt tgatgactat acatatcaaa
     8761 aagcgctgtc aattctgcta aacgcttttc ttttttttgt gtgtctaatt cataggcagc
     8821 tgaaatcaag tcccaatatt ctccagccgt caattgtaaa aaaatatctg gggaatcagg
     8881 cacataaccg attttttgtt tgatactcaa tcgattttcc gtcaatttca ttccatctac
     8941 taaaatcgtt cccgatgatg gttcaataat actaactaaa cttttaatcg tagttgattt
     9001 tccggcacca ttatgtccta aaaatccaaa aatttcccct tgtcttatcg agagagacaa
     9061 gtcttttaat gcttgttttt tcccgtaact tttacttaca ttgatgaatt caatcatttc
     9121 tgtactcctt ttgtttgtta ttacttttta ttgtaccctt cgttattggt ggagtaaatg
     9181 tcaaaaagag tgcataacaa aaaaggatag aaacgactag gctgctactt gggttgttct
     9241 cttctacagg aaaacactct tctaacaggt aagatatgag tctttgtttt ctttaaaatg
     9301 attcattttc tatcttttct tgcataaaat tctttagttt atcaatactt ctctttccca
     9361 tctctagttg ttctccattt gcaaatgtta ctatttcgtt tactctgcta atagatgtaa
     9421 tgttttcagt attaatgata taagctttta aatctttaca taaatactca tattcgagtg
     9481 attttttata ttttttaatt gtgccgttta cgagaatctc ttcatctttc aatactaggc
     9541 ctattttatt tttataacct ggcatgctca ttagataaag gatttcatcg taatggatat
     9601 agtgatcgct attaccataa cggacagttg tccacctttt tttcgtagca tgttgaacag
     9661 gatagttttc tttttctttc aataagtaac tttggatgct ttttttattt ttttcataag
     9721 tgaattcttt tatcaaataa ccactaggcg taatctttcg attaataaca gttattgctt
     9781 tattcggatg agacgttaga taaacaattt tacacttttc attcttttct ctaagcattt
     9841 cgcctagttc gataccgcta taataggcgt tcaaatcgat gtctaggaaa aaaatatctg
     9901 aggaatagat ttcattattt ttaatgaatt caacaaattg tataacgttc aatccctgaa
     9961 cgatctcaaa tttccaagga cttaataaaa ttctggattc ttccaaaatt tctactagca
    10021 ttttttcaaa aaccaaacta tcatccaaaa taaatatacg cgttaccata aaaagtacct
    10081 ccactcgata ttttactatc aaaatcattt catacaactt ttcaacatac atgttaggaa
    10141 taaattgtaa ttctcttcac aatcttttcc aacacctttg aaaccgatat caaatacttt
    10201 caggatgctg cttctaaaat aaatatcaaa caaatgaata catcatgcaa aaaaagccag
    10261 acaaccgacg tccttgcgtg tcagctgtct gagctatgtt tatttatttt gttcttttaa
    10321 aaagaacgat acacatactg atttttcgga gcagagactt tctcagcgtt tgtaacaact
    10381 acagatggga tttcacgctt gaatggttga taatagtctg attggatggt tccttctatt
    10441 ttataccatt catcattttt aaccgttact ccttccggca tatgcgtcaa caaaccaaag
    10501 actcctgaat ctgccacaca atggataatg ccgaatcgga acaagaagat atctgtattg
    10561 ctatcgttcg gtgtttggta aacaaatcct tcatagctga tttttttgcc aatgaattcg
    10621 ctagggtaat tataaattag ctccataact tctaaatagt tttcatctgt gatcttgata
    10681 gtttgcttat ccccatactt ttctttcaac tcattcattt ggtctaagta gtctgatttg
    10741 ttgaaataaa tactggtatc cggctttaag tattgtgtct gcatctccgg atcccctact
    10801 gattctttac ttactgggaa attaaatcct ttggcttcta cgatcgtagt gtcgagacta
    10861 actgttggaa acaacgtccc cacgattact ggcaaagcta gcagtacata agcgattcca
    10921 cgttgataag gttttgacaa cccatggtca tgatcgtgct cgtgtgcctt ttcttctgct
    10981 tttccgtttt tgacccacaa atacagctga actaaagcca aaagagcaga taaaatcatt
    11041 gaaagaatag ctaagtagcg ataatggaca ttgatatatt gatcgagttt gccagaaact
    11101 tgcaagtaca tcatcaattc gaaataccca gataaaatca aaaaccgcag catattttcc
    11161 ctcctaaata aataatgtga atccaataac gctaagggca atcagtccga tcagcgataa
    11221 aataaagcgt cctgtaaaat atcgtttcat catcagtaga tttttgatat cgaccattgg
    11281 gccaaagacc aaaaaggcag ctacaggtgc tgtgccgaac agacttaaca aagaagatcc
    11341 tataaacgca tctgcttctg agcaaagaga catcgtaaag gccaataaca gcatgatgat
    11401 aatggctaaa atctttgttg agccgagcgt tagcataatt ctagttggta aataagtctg
    11461 catcgcagct gcgattaatc cgccaatgat caaataacga cctgtatcaa aaaattcgtc
    11521 gattgaatgt gtcaacacat gcccagtttg atggatcagc tgattttttg gttcattctt
    11581 ctcactttgt tcttcttcat ggacatgatg atggtgattt tctgctactt tagacgtgat
    11641 tttttctttc aatacagcgt ctttttgaaa ataggcaagc cagacaccaa tcacaagggc
    11701 aacaaaaaag ctgcctatca cccgccagct tgccatctgc caagaattgc caaatgcgat
    11761 aaaagtggaa aaaatcacga ttggattgat gatcggagca gtcagcataa aagcaaacgc
    11821 tgtgtgaact ggtacgcctt ttttaacaaa ttgatgaacg atcggtacga tgccgcattc
    11881 acatgaagga aagaaaaatc ctaagatcga accagtaaaa atagagaaga tacgattttc
    11941 aggaagccat ctcttcacac gttctggggt caaaaatact tgtaaggcgc ctgagataag
    12001 acagcctaat aatacgaaag gtaatgcttc aataacgatc gataagaaaa tcgtactcat
    12061 ctgcaaaacc gaatttggaa taaaagaaaa catgagtttc ctccttttta tttctagttc
    12121 attcgctttg caaatatacg cttttattca aaaaaaacaa gttgctctgt aaatttttac
    12181 acaactctta ttttttacca aagcacttca attgactttt tctgttattc ccattaaatt
    12241 aaggtctcat acatatcact tctatcataa aagggagaat aaaaatgaaa caaaccacta
    12301 acttgactga agttcaagac atactgcaac agtcatccgt tgccgtcatt tatctttcga
    12361 tgcctaattg cagtgtttgt cacgctgttc gtccacgact agaggaactt ctcacacatt
    12421 atgatattcc ggcacttcat ttggatgcat ttgaaacacc agaagtagct agtaaatttg
    12481 aagtgctgac tgcgccagtt gtcctgattt ttcatcaagg aaaagaagtc tttcggcaag
    12541 cacggttcat cgactttaaa aaaatccgtt atctactaga tgaactgaca gcagaagatg
    12601 attccctttc ttatgaagaa atcttccgaa caaaataatc gttgtccaaa cagaaaaaag
    12661 cgattgaaca agtgaaagtt ttgccttcat ttgttcaatc gctttttatt tttattctgc
    12721 tgtattttcg gaatgcgcat ttgcgtcaga atgcaagaaa tagatcaagg tttgcaattc
    12781 attcgtcaaa tcaacatttt ggatcaatac atctgacgga gcattcaatc gagcagcggt
    12841 aaagttcaag attcctttga ttcctgcttc cgttaactga ttgactactt cttgtgctct
    12901 ttcagcgggt atcgttaaaa ttgctacttc gatttgttgg atcttgattt gttctgacat
    12961 atcttccatt ggataaacgg ggataccgtc tacgatgcgc ccaacgattt cctcattcac
    13021 atcaaaagca caactgatac gtatgctatt actttgatgg aatttgtatt ttagtaaagc
    13081 acttcccaag ttccctacac cgatcagcgc aacatttgtc aattgatcgt cgtttaatgt
    13141 ctttgcaaaa aagtgcataa gatcttctac atcataacca tacccacgtt ttcctaattc
    13201 gccaaaataa gaaaaatctc gacggatcgt tgcactatct acttgaacgg cttcacttaa
    13261 ttcagttgaa gacacttttt tctttccagc attatttaaa atccttaaat agcgataata
    13321 caaaggcagt cttttagctg tcgcctttgg aataatatga tctttcacga aatgacctcc
    13381 acgtattgtc taattacatc tttgatttct ccatcatagc agtatttata ggaaaaaatc
    13441 aattccattg ctcagatatt gtgaaatttt attctttatt catttattta tcatttctgc
    13501 aaatctcgca gtataatgga atttatggta gactactaat tgaaaaatag ttttttattt
    13561 gaggagaatt cacaaagtag aaaagaggat tccatgatat tattacaagc caatcagatt
    13621 gctcgccatt ttggtgcaga agtcttattt gaaaacatac atttagaaat cagtacaggc
    13681 gctcgtgtcg ctttagttgg cagaaatggc gctggaaaat cgactttatt aaagatcatt
    13741 gctggaattg aagcacctga tgaaggaaag atcgctaaaa ataaaacagc gactctcgga
    13801 tacctcgctc aggacacagg acttgattcc aatgaaacag tttggaacga gatgctgaaa
    13861 gcttttgaac aagttagaca aatggaagag cggatgcgcg agctagagat tttcattagc
    13921 gaaggtacgc cagacacacc tgcttatagt tcttatttaa aagaatacga ccggctgcaa
    13981 cacgattttt cagatcgaaa cggctatggt tatgaaaatg aaattcgttc cgtattgcat
    14041 gggtttaaat tcgattcttc attttatgat cagaaaatcg atactttatc aggcggacag
    14101 cgcacacgtt tagctttagc tcgcatgctt ttgcaacacc ctgacatttt gattctagat
    14161 gaaccaacga accatttaga tatcgagaca ctttcctggc ttgagaatta tctgcaaagc
    14221 tatactggtg cattattgat tgtttcccat gaccgttatt ttttagataa agtagtcaat
    14281 gaagtctatg aattaagcag aagaaaaatg cgccattaca aaggtaacta ttcgaaatat
    14341 ctagatttga aagcagaaca gttagcaagt gaatggaagg cttatgaaaa gcagcaaaca
    14401 gaaatccata aattagaaga cttcgttgct cggaaccttg ttcgcgcctc taccacaaaa
    14461 cgagcgcaaa gccgcagaaa gacattagaa aaaatggacc ggctggatcg tcctcaaggg
    14521 gatgaaaaac aagcaaactt tctattcagt atagaaaagc cttctggaaa tgtagtcttg
    14581 caaatcgaag atgccgctat cggatatgat aatgtcacct tatctgaacc aatcaatcta
    14641 gatatccgtc gtcaagaagc gattgctcta gtaggtccga atggtatcgg gaaatcgacg
    14701 ttgctgaaat caatcattca ccagatccct tttatccgtg gaaaagaaac gctagggaca
    14761 aatgtcacca tcggctatta cgatcaaggt caagctgatc tgcatacaaa caagacgatc
    14821 ctagcagaat tgtgggatga gcatcctacc actccagaaa aagagatccg aagtgcttta
    14881 ggtgctttct tattttctgg cgaagatgta gaaaaaccaa tccctctgct aagtggcggt
    14941 gaaaaagcac gggttgcttt agccaagtta gcgatgaaca aagaaaattt tttgattttg
    15001 gatgaaccaa caaaccattt agatattgac aacaaagaag tattagaaaa tgcattgatc
    15061 gattatgacg gcacactgct ttttgtttcc catgaccgat atttcatcaa tcggatcgcg
    15121 acaaaagtcg tcgaactctc tgaaaatggc agcaaagtct atctaggaga ctatgattat
    15181 tatttagaga aaaagcagga agaagaagaa atcgccgaat tgttggcaca agatgagcca
    15241 gaatctgctc ctgctcccac gaacaaatct gattattacc aaagcaaaga acagcaaaag
    15301 cttatccgta gccttcaacg aaaaattact caggttgaag aagaaatggc gcggatcgat
    15361 gaatggatcg atcagttgga acaagaaatg gtcgcgccag aaaacctgga agatcacgta
    15421 aaactcaatg agctgaacca agatttagaa gctgctagac aagatcaaga aacaaaattg
    15481 acggaatggg aagaactaag cttggaatta gaagaatatg aaaattaacg aaaaaaccaa
    15541 aacagaaacc attcatgctg ttttggtttt tcttttttta ttttatcaaa caaaaattcc
    15601 atatttacct ttttcaccaa taagaagacc aattactagt cattctcact aaagcttcta
    15661 aataatagta atcaccccaa atacaaggtg tatttacccc attatttttg ggcttattat
    15721 aaacagactg tgttaaaaag ccatcttctt cttccgttgt agcatatctt tctttcaatt
    15781 gtcgcataat tttccaaaca gcagactggt ataagttctt ttctgttttg tctaatagac
    15841 ctgattctat taattctaat aatccacaaa ccatgatcac catactagat gtatcttttt
    15901 cttctctgct agaatcatca aagatcaaat cccaataaca aatggtatct tctggcaacc
    15961 gattcataaa ataattggct aatattttgc ttaaatcaaa atatttttgt tctttcaaat
    16021 aacgataact taatgcaaaa ccgtaaatcc cccatgcttg gcctctagcc caacaggaat
    16081 tatcactata accttgatgc gtacttccat atcttggttt tccatctttg acatccatat
    16141 aaaatgtatg ataagttgaa ccatcttctc ttactaaata atctgctgca ttttgaatat
    16201 gagcctgagc agctttttta tatttttgat ttccagtttc ttcactcgcc caatacaata
    16261 atggaagatt catgcaacaa tccatgatca ttctaccttg ttgtgaagga tcactaggat
    16321 ctccccaagc ttgtataact cctgccttct cccaaaaacg ctgaagtaat gtttctgcag
    16381 catcaattga agcttccttc atttttcgat ttcccgttat tttataatct gctacggttg
    16441 ataaagaata caaaaaacca agatcgtgat gattagtgat aatttgacag tcaatcctgt
    16501 ggataaaatc tatatctgct ttttcagctg tttgttgaaa taaaggatca cccgtcttct
    16561 caaataacaa ccaattaatt cctgtccaaa atccttctgt ccaaccaata ttgtctctta
    16621 atggataacg tccttttata ggacactcgc ttgggaattg atactgactg ttactgatac
    16681 gtttgattaa cctctccgtg tgtctgcgac aacgctcgat ctcattattc cattcttttt
    16741 ccattaattc tttataacat tcatttatcc atttttctgg atgtattatc tcttcaaaca
    16801 tcactttatc aagcatttcc ccaccagcct ttagcataat tttagtcttt ttttattgtt
    16861 tttattttgg atagttagcc cggttgtccc atcaaaatca attttgggac gattgttcca
    16921 tacttctaaa ctataatccc gatcttgatg agcaaccact cctgttccga gccaatgggt
    16981 tccttttcca aatgtaccct ctaatccagg aataaaagtg ttttcccatg tcatcaagtt
    17041 tgtattgggc aaacccataa tagctgtgga ttttcgttta atagtatcgt cacttaaaca
    17101 gataatacct gaaaagccag cttcactcac cctatagttt tccttgtctt cttctatgat
    17161 tattccttct ttctcaggag aacattcaat agcaaaccct gtctcatata gaacatattc
    17221 tgtatctaat tctactttgt gtacgcgaat ctgccagcct tcaaaaggaa taagccaagt
    17281 tctgattttt gcctgtaaag taggttccca tgtagaggca agtacctctt tcttacatac
    17341 aatgtctcgt acattatttc gaacgatgaa ctgtccatag gttttgatgc tctcattctt
    17401 aaaactggtc gtgatatatg tgtccgctcg ctgaatccct agcattgaat ccattgccat
    17461 ttctgctttc aattgattcg ctcgcggtat cgaaaaacca aattgactag aataagcaaa
    17521 ttttaaatat ttttcattgg tcaatgtatg gaaatttggc cctaattgtc ccgcattcaa
    17581 aaaaaatgta tgtccattat catgttgtat gagcaaattg gcttctgaaa gaagtttagt
    17641 tccttcacga ataggcatag gcatttcttt agccgtccaa tactcatggt cttcaggtag
    17701 cgccaacaat aaaaaaatct tattcagcca taatggagat aacgtactat tatagggttc
    17761 agtcaatgtc aattgagggt aggtataacc aatattcagg ataccttttt catcaaatat
    17821 ttctttttgc atccaccatc ttatattccg attgactaac cccttgattt cacctaattt
    17881 aaaaggcaaa agatcggccc acaacatagc tgaccaaaag cttgaaactg caaaacgata
    17941 aatcatgctt cgaccaaaag gcacatttgc accatcttcc gcaaaaaaat gaatatagtc
    18001 tctagaaaaa tcaatagctc ggttcttata tatctggcta atgggctttt ctggttctag
    18061 tacgctataa atcaaaccat aataatgaaa tgcaaaagga ttataataat cttggcgacc
    18121 tcttgaactg tctcgatacc agccattttg aagataacaa ttttctatat tatcaaatgc
    18181 ttctttcagt gctgattctt taactggata accaaatttt tggataattg ttccgacaat
    18241 tatcttaaaa aattgccaat taccatctgc acattcatat tcaaaaattt gcgagaacca
    18301 atgaataatc tggctttttt ctcctgtatc taattttttc cataataatt gttcatgatg
    18361 atataacgct aataacattg cgggcatttc taccatacgc tggtctcttt catgtatttc
    18421 tccccaataa tcgggatggg aaggatctgt tccagctttt attcctgata gaattaattt
    18481 caaccatcgt tcatctaatt ggtcaattgc gggccccgct ccccataaaa cccgagagaa
    18541 tccttccatt cctgcaattt tatttccata tcctacccct tgatgtatat aatcaatttg
    18601 tgcgccactt gctcgataaa acggctggag tggttgattt atctttttaa ataagtcaaa
    18661 gtaatcctgt ctggtcctta atagtggtac tggatgtttc attgtatttt ctcctctttt
    18721 tactaccaaa tagctaattc cgactgttct aatcgaagta agccttcaat aaaaaaataa
    18781 tcagaataga tcagtggcac attataagtc agttctctat ggtatgcttc tgctccgcct
    18841 ccaatgatcc catcttcatc catattccaa tttgcatagt gcttttctgt cttttggagt
    18901 atattgatag cagcttcatg atacattttt gatcgtacag aggaaacata tcctgctaat
    18961 tccagaagac cgcatgcagc gcatactcca gcactggtat caatattcga atcttttaca
    19021 gcaaaatcaa tgagaggaat ataaccagtt ttttcgattt tctgaataaa atttactgct
    19081 atcttttctg ctatagctag atagtacgga ttttttgtgt aacgataact taacgcgaat
    19141 ccatataaag cccatgcatt tcctctgctc caacaagaat tctcattgta tccttgcccg
    19201 ccaagtaacc gaatatattt ccctgattct gcatcaaatt ctgcgatatg cccggttgat
    19261 ccatctttcc tcactagata cttagctgtt gtatctgcat gctgccgagc aattttagag
    19321 aacctcggat caccagtttc cctcgaagcc caatacagta atggtaaatt catcatacta
    19381 tcaataatca tccaaccagg tttatggtca ttccatgcta ctaaatagtt ccctgaaata
    19441 ttatagcgtc cagcaagtac cgtagctgca tgtaacccta gttgtcgact atgtttgttt
    19501 tgagactgtt gataatgtgc aatagccgat ggtaagaata aaaaacctac atcatgatga
    19561 acgtctgaaa aatggtacag ggcagattct aataattgtt cttgttgtat tgctgcctct
    19621 ttgaactttt ctcgttttgt cttgtgaaag agctgccata aaataccact ccaaaaacca
    19681 ttggtccacc agtcgattcc tctgtccttt attacgtctg tatattttcc gttgtaagaa
    19741 atatatggaa ttttattccc cattctgtct aattccgcat ctatcttttc agaagctaca
    19801 ttcaaaattt ttcttgacca ttccttcgtc tgttcattca tggatatccc gccattcttt
    19861 taatttttat gaatgtggag ttgctcctag aacgaactag atggttaaca ttcgttattt
    19921 tttttactta tttgcagctc caatgtcatt ctccttaaat ttagactgcg cccacacata
    19981 aatcaagacc attgggatca ctgaagttgc taaaattagc ataattgcgc cataattaat
    20041 tggctcacct gtactagaaa ccgtcatatt tttgataatt aagggaaccg tatatttatc
    20101 tttatctgaa agcatgacta atggaaatag atattgattc caacttccca taaagataag
    20161 taaaccacta gtaataatcg taggtgataa aatcggtaca gcgattttcg taaaaatcac
    20221 ccactcattg gcaccatcga ttctggcagc ctccatcagt gctgtaggaa attgactgct
    20281 atattgtcgc atcataaaca ctgaagttgt actggcaatc gaagggatga tcacacctgc
    20341 ataagtattc gataatccta aacgactcat aatgtaaaat aaaggaatca atgtggtaaa
    20401 aaaaggcacc atcctagata gcataactgt attgaacaac agtttattcc ccataaaacg
    20461 atactttgct aatgcataac ccgccattgt agaactggct gtagctaaaa ctgtactgat
    20521 tacagcaata acaatcgaat tccaaataat caagggataa ttatatctcg ccatgatggc
    20581 ttgccagttt tttaatagca tatccccaaa cttgaaattg attccgccac ttaaaatttc
    20641 ttgattactt tgcgttgaag ctacaatcat atataaatat ggcatcaaaa atattaaggc
    20701 accaaacaca ataatgacgt acgtaaaaat tctgctttgt atcttttgtt tagtcatttt
    20761 tatcacctcc gaatttaaat tgaatagccg ataatataac agatacaaac accatcgtcc
    20821 aggcaatagc agaggctttt ccaaaatcaa ccatttcaaa acttgtttta tataaattga
    20881 ctcctacgac caaagctgaa ttttctggtc cattggaagt cccaaagaat atatttggga
    20941 tattgaaatt acccaagcca ttgatagtgg ctaaaactgt ggccattaaa atgattggct
    21001 ttagcatggg gatcgttaat aaaaagaatt gccgaaattt cgatgctcca tctatttcag
    21061 cactttcgta tatctcttta gaaatccctt gaagaccagc taaaaataaa atagtgttat
    21121 atcctacact aagccaaatc atcgtgatga tcattgatat tcgtatccaa aaaggatttg
    21181 ttaaccactg tacaccgtta attcctagcg cattcaaaaa tccattgaat aacccagtcg
    21241 gattgaaaaa agtcatgaat acggaagcta cagccaccgt tgatgtaatg gttggaatat
    21301 aatagacagt tctaaaaaat ccttttcctt ttaactgtgc tgaattcaat aaaacagcaa
    21361 agtaaatagc taatagcatc gttattggaa ttgatcctgc catgataatc aaaacattcg
    21421 tgtaagattt aataaacaat ggatctcgga agatagctag ataattgtca aatccaacaa
    21481 attcaaatga gtagccaatt ttcataaaac taaaagcaaa cgagataatg atgggaatca
    21541 aaatcgtcac aataaagaaa ataacaaaag gtgtgaccaa tccataagca ctttttttat
    21601 gagacgtatc tgttgctttt ttcttgctgt tctttattgt cttgcttggt aacgaagatt
    21661 gtatcatcgt taagtcctcc taatattttt taatcaccag ttaattttac gccgtactta
    21721 tgagcaaaat tttctgcttc ttttagatat gaattttcaa aatcacctgt ttgccaatag
    21781 ttatatgcag cggtagtcaa ataagacgta gcatctgaat aagtggctgg taaaacagta
    21841 tttgatgtat tttcattgat tttattcaat agttcatagt atttttgtcc tccttagtag
    21901 tcaaactttt tctcagctgc ttctgtttga taggccaatg agttagatgt agccacgccc
    21961 agctccagtg cgttggctaa gcattcttca tctgtcagca taaatgtaag aaattgttgt
    22021 gccacttgtg gatttttggc atctttaggg acataaaaac ttgatcctcc tgatactgca
    22081 ccttttcctg gattttcttt tgaaaaagga atcagtggag ccatgcgcca tttgtcagat
    22141 gcatcaggaa aattcaaaga catattcgta gcataccagc cgccagcaac aaacattgca
    22201 gattcttgaa atgctttctc agcatcttgt gcaccgtaga aatgtacaat atctgagtcg
    22261 atcatttctt tgattaactt tgcagcatgt ttcgcttctt tagtattcag acggatattt
    22321 ccttcttcat caagcaaaga ttgattctgc tgggctagca tgttgataaa caattcttgg
    22381 tccccagatt ctggcaaggc aattccaaaa ctaccagttt tttcttttaa tgcttttgcc
    22441 acctggatat attcttccca agaactgatt tcttcaaaat ctacacctat ttcagcaaat
    22501 ttttttggtt gataataaca aagtgctggg gtaaaatcac tagcccaagg aataatcgtt
    22561 tcattactcg tttgttgacg caaaatattc aatttttgat cataaaactg atcgccatat
    22621 ttgtcataaa atccatattc atcagcacta taaaaagcat cttgaaattt ttccagcaca
    22681 cctgctgctg aagtgtctgc catggagata atatccggca tatcttcgtg tgttaccaat
    22741 tttggggtga tcatttgtac tgttgctgtt cccgaagcta cattcacaat ttttaagtca
    22801 atatttgctc cagttttgcg gttatagatt tttgcagcat tttcaacata gtttgtcagt
    22861 ttgccgtttg cgacatatac ttctaatgta gtggcttttt ttatcattgg atctgcgatg
    22921 tttgctgtta cttcttcgtt agtttttcca catgcactta agctgaataa tagggtaatg
    22981 tttagcaaag ctatcaccaa tttgtatctt tttttcatgt ctatcccttc tttcttttca
    23041 agttcttata taaaacgctt tcacttatgt atattaacgg aattagtaac acaaatattt
    23101 atataaaaaa atattttact
//
LOCUS       DACDAF010000044        22877 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.044, whole genome shotgun sequence.
ACCESSION   DACDAF010000044 DACDAF010000000
VERSION     DACDAF010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.044"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..162
                     /locus_tag="IVZ69_001560"
     CDS             <1..162
                     /locus_tag="IVZ69_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP8183647.1"
                     /translation="TIILTIPTIVGSIYGMNIKLPIAERDDAFIWLVLLTLFICIVTT
                     YYLKKGKFL"
     gene            235..351
                     /locus_tag="IVZ69_001561"
     CDS             235..351
                     /locus_tag="IVZ69_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HAP8183648.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(406..2088)
                     /gene="recN"
                     /locus_tag="IVZ69_001562"
     CDS             complement(406..2088)
                     /gene="recN"
                     /locus_tag="IVZ69_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HAP8183649.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(2106..2555)
                     /locus_tag="IVZ69_001563"
     CDS             complement(2106..2555)
                     /locus_tag="IVZ69_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HAP8183650.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(2662..3480)
                     /locus_tag="IVZ69_001564"
     CDS             complement(2662..3480)
                     /locus_tag="IVZ69_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HAP8183651.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(3489..4379)
                     /locus_tag="IVZ69_001565"
     CDS             complement(3489..4379)
                     /locus_tag="IVZ69_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP8183652.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(4381..4605)
                     /locus_tag="IVZ69_001566"
     CDS             complement(4381..4605)
                     /locus_tag="IVZ69_001566"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HAP8183653.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(4610..5947)
                     /locus_tag="IVZ69_001567"
     CDS             complement(4610..5947)
                     /locus_tag="IVZ69_001567"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HAP8183654.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(5948..6802)
                     /locus_tag="IVZ69_001568"
     CDS             complement(5948..6802)
                     /locus_tag="IVZ69_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HAP8183655.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(6899..7348)
                     /gene="nusB"
                     /locus_tag="IVZ69_001569"
     CDS             complement(6899..7348)
                     /gene="nusB"
                     /locus_tag="IVZ69_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HAP8183656.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(7341..7766)
                     /locus_tag="IVZ69_001570"
     CDS             complement(7341..7766)
                     /locus_tag="IVZ69_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP8183657.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(8012..9076)
                     /locus_tag="IVZ69_001571"
     CDS             complement(8012..9076)
                     /locus_tag="IVZ69_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HAP8183658.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(9248..9493)
                     /locus_tag="IVZ69_001572"
     CDS             complement(9248..9493)
                     /locus_tag="IVZ69_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP8183659.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(9632..10006)
                     /locus_tag="IVZ69_001573"
     CDS             complement(9632..10006)
                     /locus_tag="IVZ69_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HAP8183660.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(10089..11003)
                     /locus_tag="IVZ69_001574"
     CDS             complement(10089..11003)
                     /locus_tag="IVZ69_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HAP8183661.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(11024..11827)
                     /locus_tag="IVZ69_001575"
     CDS             complement(11024..11827)
                     /locus_tag="IVZ69_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HAP8183662.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(11860..12849)
                     /gene="manX"
                     /locus_tag="IVZ69_001576"
     CDS             complement(11860..12849)
                     /gene="manX"
                     /locus_tag="IVZ69_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HAP8183663.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(12952..13443)
                     /locus_tag="IVZ69_001577"
     CDS             complement(12952..13443)
                     /locus_tag="IVZ69_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIB"
                     /protein_id="HAP8183664.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(13634..16468)
                     /locus_tag="IVZ69_001578"
     CDS             complement(13634..16468)
                     /locus_tag="IVZ69_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8183665.1"
                     /translation="MAKRIDRIYMYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNS
                     SKDLNQLVREGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDT
                     KDIFAKIIGANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAH
                     HVIDEETELIVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLD
                     EIHRLPPEGQEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRI
                     PINIKLPAFEKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQL
                     KSNIQLVCARGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKIT
                     VAPNDTIMKIQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFY
                     KDHGFSFNADSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKK
                     INLGEERHTNDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLR
                     ANQASGRIGVVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNV
                     QEVDEGSGVILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDL
                     DMLHESLKNFRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNK
                     RQETELEVLALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVI
                     LDQLLMESELEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTT
                     GIGDEEYGFKINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLED
                     QIKVKVPIEEMYYLLRLVHNQLDKKEYTVP"
     gene            complement(16875..17168)
                     /gene="rpmA"
                     /locus_tag="IVZ69_001579"
     CDS             complement(16875..17168)
                     /gene="rpmA"
                     /locus_tag="IVZ69_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HAP8183666.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(17181..17525)
                     /locus_tag="IVZ69_001580"
     CDS             complement(17181..17525)
                     /locus_tag="IVZ69_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HAP8183667.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            complement(17552..17860)
                     /gene="rplU"
                     /locus_tag="IVZ69_001581"
     CDS             complement(17552..17860)
                     /gene="rplU"
                     /locus_tag="IVZ69_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HAP8183668.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            18142..18783
                     /locus_tag="IVZ69_001582"
     CDS             18142..18783
                     /locus_tag="IVZ69_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP8183669.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            complement(18845..20476)
                     /locus_tag="IVZ69_001583"
     CDS             complement(18845..20476)
                     /locus_tag="IVZ69_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HAP8183670.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(20599..20958)
                     /locus_tag="IVZ69_001584"
     CDS             complement(20599..20958)
                     /locus_tag="IVZ69_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HAP8183671.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            complement(21117..21190)
                     /locus_tag="IVZ69_001585"
     tRNA            complement(21117..21190)
                     /locus_tag="IVZ69_001585"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21154..21156),aa:Arg,seq:tct)
     gene            complement(21499..22182)
                     /locus_tag="IVZ69_001586"
     CDS             complement(21499..22182)
                     /locus_tag="IVZ69_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HAP8183672.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            complement(22310..22828)
                     /locus_tag="IVZ69_001587"
     CDS             complement(22310..22828)
                     /locus_tag="IVZ69_001587"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP8183673.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
BASE COUNT         6582 a         5043 c         3808 g         7444 t
ORIGIN      
        1 acgattattt taactatacc gacaatcgtc ggcagtatct atggaatgaa cattaagtta
       61 cctattgctg aaagggatga tgcctttata tggctagttc tattaacatt atttatttgt
      121 atcgtaacta cctattattt aaaaaaaggg aagtttttat aaaaaagccc tcttgtggaa
      181 atggaaaaaa gattgtacac ttgaatcaac taattaatga cgaggttgaa aacaatgcgt
      241 gaaaaaaaac aaacaagtac ttttgctaaa gtaacaaaat ttgtcatttg gacaatgctg
      301 attttaacga ttggatctgt tgtattgact gctgtaatga gtgtcatgta aaaataaaat
      361 atagctatca gctgctgaaa aggacctgaa ccactgcgag gtggctcagg tcctttttgc
      421 gagtttcaat agttcttttg catgttcgag tgtgagtttt gtaatctcac ttccagccag
      481 catacgtgca atttcttctt ctctttcttt tgttttcaac tctgaaacag aagtttgcgt
      541 acgtccatca atcactgctt tcacaatata atattgatag tcggcgactg cagcaacttg
      601 aggcagatga gtgatgcaca aaacttgaga gtatttcgat atttgagaaa ttttatctgc
      661 gatggcctgt gcaactcttc cgctcacacc tgtatccact tcatcaaaaa taatacttgt
      721 cacaccttgc tcagaagaaa aaatagtttt caaagcaagc aacatccgag acagttcgcc
      781 accagaagcg actttcacca aaggcttcag tggctctcct ggattggtcg taatataaaa
      841 ttcgatttgg tcaaatccat catgattcaa ttgtctattt tcttctttta agaaacgtac
      901 ctcaaactca gtgttttcca tatacagact tttcaattca tgcagaatgg atttttccaa
      961 ttcttttgcg atttttttac gcgcttcatg aagatctgcg gcttgttgct gaagtagaag
     1021 ctctttttgc tctagttcct ctttcatttt gtccaattga ccttctgaaa aatcagaaga
     1081 agctagctct tcggtgattt cgtcatagta agccaatatt gactcaatgg attcgccgta
     1141 tttacgtttc aactgtcgga ttaattctaa acgttgcgta acttcttcta aacgactctc
     1201 atctaactcc aataaatcaa tctgacgact catatcgccg attgcatctt gcagcaaata
     1261 gtaagcactt tggatatttt cataaattgc ttcatactcc acatctagat gggcgatccc
     1321 ttgcagttct gaaacggcca agccaacacc atctacactg ttttgttcat tattcgtcag
     1381 tgctccgtaa cctgcagcta atccatcagc aattttttga taattgctaa gtttttctct
     1441 ttcttctttt aatttctctt cttctccgac ttgcaaatca gcagcagcta tttcttcttg
     1501 ctggaaatgg agcatatcta ttctctgaac ataggatttt tcattttgct gcacttttcg
     1561 tacccttttt tccagctcac gataagagat atattcttgc tgataactct ttttcttctg
     1621 ttggaaagct acatctccaa aacgatccaa taaagcaaga tgtgattcag gctggagcag
     1681 ttcctgatgt tcgttttgtc cttggatatc tactaaataa ctgccgattc ttctcagatt
     1741 agctaatgtg ataatatgac cattcactcg acaaacattt tttccagtta aggacatatc
     1801 ccgtcgaaca atcagattgt cctcatctgt ttcgatccct aattcaacca tcagttcaga
     1861 gaatccttct tgttttggta gttcaaacaa cccttcaagc acacattttt ctgctccttg
     1921 acgtatataa tcgcttgaac ctcttcctcc tgctaacaga cctaaagcat cgataataat
     1981 ggatttaccc gcaccagtct ctccggtcag cgcggtcatt ccttcgtgaa aagaaagccg
     2041 caattccgga ataatcgcaa agttagtaat actgatttct tgtagcatca cattcgctcc
     2101 tcaacttaaa ggtaatgcag gaagtctttc ttcaataaaa ctgcctggtc ttcagttcgt
     2161 gtaatcatca aaacattatc gtcatcattg ataatcgaaa ataattcttt cttgtaacgt
     2221 ttatcaatca aatttgctgc tgccgaagca tttcccggca atgttttcaa aataacaaat
     2281 ttttccattt ggtcaactgc cacgaaagcg tcttttaata gtttttccaa tttagtattt
     2341 acatcttcgt ttgtttcagc tggtatgcta taacggtagc cgccatctga agccggtacc
     2401 ttgatcagtt tcagttcctt tatatctctg gaaatcgtag cttgagtaac agatattcct
     2461 ttgcttttca ggatttcaac aaattcttcc tgctttcgga tatcttgctc actcaacaat
     2521 cgagtaatca aacgatgccg atcttttttt ctcattacgt cttcgctcct tagcatattc
     2581 ttcttaatca atgatagctt atttccttgg tataataaag aagaatccgc atacttctca
     2641 cttgattttc acagttacaa tttatttatg gtcaaactgt tcgtgtgcat ttgaaaccac
     2701 ttctgccata ttaatagctg aattgattgt tccgctttcg ggtactttcc tcaagtgagc
     2761 caagaactcg atatttcctt ctccccccgt gatcggagaa taacttaatt ccagcacatc
     2821 atatccacct tgtgccgcaa atgacaaaat gtcttctaaa actttttgat gggtctgagg
     2881 gtcacgaaca attccgtttt tccctacagc ttctctgcct gcttcgaatt ggggtttgat
     2941 taaagcaatc acttctccct cttcttttaa aatagcatgt aatggaggca gcatcagttt
     3001 tagtgaaata aaagaaacat cgataacagc aacttctgga attcctaagg taaagtcttc
     3061 gggttttgca taacgaaaat tcactctttc cattacgacg actctaggat cttgtcttat
     3121 tttccaagct agctgattgt agccaacgtc taaagcataa ctcatttttg cgccattttg
     3181 caaagctgca tcagtaaatc cgccagtgga tgcaccaata tctaacaatg tttttccttc
     3241 aacagataga tcaaatgctt tgagtgcttt ttctaatttt aatccccctc gagaaacata
     3301 aggaagtttt ttacctttga ctcttaattc actactcact ggaatttttt ctcccggttt
     3361 atcaaaccgc tcgttttttt cgttgtaaat caaaccagcc atcactgaac gtttggcttg
     3421 ttctcttgtt tcaaataatc cttgtttgac cgctaataca tctacgcgtt ctttttccat
     3481 tctttccctc atttctccac atcaaattgc ttgatcatct ggcgcatcag cccgccatca
     3541 aaagaaaaaa cgtcctcttc taatttgtct atgatcttgt tggcggataa cagctcaatc
     3601 tccaacgcct cacgtgtctt ttctaggcct aataaacgcg ggtaagtatt tttttccata
     3661 cgttcatctt taccagctgt tttccctaat gttttcgttg taccaatcac atcgagtaga
     3721 tcatctctta tctgaaaagc taaacctaaa tgttcggcta atcgttgaag tagcaataag
     3781 atttcttcag gttgcttcgc taatatgcca ccagccagca aggcataacg aatcaaatgc
     3841 cctgtctttc tttcatgaat aaatgctaat tcttctaaag aaagcttttt cgattcgccc
     3901 tcgatatctg cagcttgccc agcaaccata ccttgtgatc ccgcacaaac agctaattgc
     3961 tgaagcagca gaagcttagg agaattacct aagtgtgcca tactgattag ctggaatgct
     4021 cctgtaagca aaccatctcc ggccaatata gctaatgctt cgccgaatac tttatgattg
     4081 gtaggttttc ctctacgaag atcatcattg tccatcgcag gcaaatcatc gtggatcaag
     4141 gaatacgtat gcaccatttc taaagcagct gctacttgat agacgggaac atcaataggc
     4201 tcatcaaagg aagcaacggc cgttaaaagt aataagggac gtattctttt cccgcctgct
     4261 ttcactgaat aactcatcgc atcatagagt cctctatccg ttgtatgctc atctaaaaaa
     4321 gacaagattt ctttttctac agcaggtaga tgaatagctg aaaagtcagt taatctcatc
     4381 tcagctttcc tcgtttccgt caaaatcaac ttcttcattt gattctgtca tcattttcgt
     4441 caaggtctct tctgctttag ctaatgtatc ttggcaatgt ttgcttaatt ccattcctcg
     4501 tttaaacgaa tctagagctg attctaatgg aacgtctcct tgttctaact gcatgacaat
     4561 tttttctaat tcttgcagtg actcttcaaa agttggattt tccatatttt tattctcctt
     4621 tgtctatctc ttgtacttgt cctttaacga ttccatcttg ataatggatc gtcagcaaat
     4681 ccccttgatg aatctcggtg acacttttta ctacttgatc atttaacgtc gtatagctgt
     4741 agcctcttcc catgattttc aatggactca acaaatcaag agattgaaca gcttgagcaa
     4801 aacgctgctg ctgttgtttc atatattgtt ggattttctc ttctaagcgt ttttctagat
     4861 aagcagtttc ttggcgagct gctttaactc gataaagcgg agccacttgt tccaattggt
     4921 ggcttaatgc gatcgtttgt ttttctttcg catgataaat ttgctgtgta gcttgatata
     4981 atcgctgttt caactggtct aatttgatgg tctgaccttc atacaatctt tcaggctgcc
     5041 gaaatacata ggaacgtcga gcacgctcga accgttcttg tttgcgctgg atctggcgta
     5101 caaacgcctg ctgcaatcta gcttgccgtt cttgaatgcg catcaactct tctgacaaaa
     5161 caggaacagc taattctgca gctgctgttg gagtggcagc ccgaacatct gctactaaat
     5221 cagcgatcgt ggtatctgtt tcatgtccta cagatgaaat caccggcgta ttagcttgat
     5281 aaatcgcccg agcaacccgc tcttcattaa acggccataa atcctcaatc gaaccacccc
     5341 cacgaccgat gatcattgta tcgaaattgc ccatctcttc tactctctgg atattcctga
     5401 caacattgtc cgctgcttgg tttccttgta caactgttgg gaacaaaacc aattggacaa
     5461 ttggatatct tcttttcacc gtcgtgatga tatcgcggat aaccgctccg cttggactgg
     5521 taaggaccgc gattcgcttt gggaaacgtg gcagcatttt tttaggccct tgaaaaaggc
     5581 cttccttcat cagcttttct tttcgttctt ccaattcttg atataaagca cctattccat
     5641 caggctccat gtgctctaca tagatttgat aagaacctcc cgcttcatat aatgaaatac
     5701 gcccaacgac aaggactttc attccttctt ttggctggaa tcgtaatttt tggaatgctc
     5761 ctttgaacat aatagcagat atttttgcat ggtcatcttt taagctgaaa tattgatggg
     5821 cattggcacg taaacggaaa ttcgatattt cgcctgttaa atatacgcgt tctaaataag
     5881 gatcggcatc aaattttctt ttcaaatact tcgttaatgt agtgacagtt aaatattctt
     5941 gtgccatcta ttcacctgct ccaaaagctt cggcagattt tacggtttga tacatcagca
     6001 tcgtgatagt cattggccct acaccctttg gcacaggagt gatccagcct gcaataggct
     6061 ccacttcatc aaatttcaca tcaccgatca gcttaccgtt agcatcacga ttcatcccta
     6121 catctatcac tacagcacct ggttttacga attcttttgt gacaaaatgt ccacgtccta
     6181 ttgctacgac taaaatatct gcttcttgtg ccagttcagc cagattttcg gttttagaat
     6241 gagcaacagt aacagttgca tctgccatca agagtagctg agccatcggt ttaccgacga
     6301 tattgcttcg tccgataact actgctcgtt tacccgccgg atcgatagaa taagcttcaa
     6361 acattttcat gatgccgtat ggagtacaag gaatcttgtc cggtttaccc gcaaggagtc
     6421 tgcctaaatt catcggatga aaaccgtcta cgtctttttc agggcggata gctaacagga
     6481 tcttttcttc atctatatgc tttggcaatg gtaattggac caatatacca tgaaaactag
     6541 gatcttgatt gtatttttca atttctgcaa gtagttcgtc ttcagaaatc gtctcaggat
     6601 aacgctctac caatgaatgg attccgattt cttttgctac acgttcttta tttcttacat
     6661 agatttggct ggctggattt tcccctacca ataaaacgac taatccggga tggataccat
     6721 tatctttcaa tttttggatt ttttcagcaa tctctgcctg cattttttca gctaattctt
     6781 ttccgttaat caattctgcc atctaaccac tcccagatat tttttgtgtt ttcattctac
     6841 catagaattt tcccgattta taacaggttt atgatgattc atagaaaaaa gctaggactt
     6901 acgccccagc ttctaattct ttcaatacat tggataaaac accgttgacg aatttacgtg
     6961 aacggtcatc actaaatgtt tttgccaact cgattgcttc atttaaagca acagccgctg
     7021 gtacatctgt cacataagtc atttcaaaaa tcgcgatacg caagatcacc aaatccattt
     7081 ttgagatccg attgatgtgc caattgtttt ttaaatgttt ttcaatcact ttatccaatt
     7141 catctttttt tgcacagaca ccgccaacta gcgtatcaag ataaacagga acaaactctg
     7201 attcatcttc gttgatcatg tcgcggtggt ctaattcgat tgcgttgaaa atcgcatctt
     7261 cttttgttag gtctgcattg aagtctaatg gaaataaagc ctgcaatgcc atttcccgaa
     7321 tctcgtgtct tgataattct ttattcattc tcttcctctt cgtcttcaaa aagttcttcg
     7381 attgttggtt gttctaattt ttcaggaaca acagctacta catggatatt gacttcagat
     7441 aaatcgatat ccgtcatgaa aaggacttgc tggctgaccc gttcctgcat ttccattgct
     7501 actttaggaa ctgaaacacc atattctaga taacagtaaa gatctacttt caagccatct
     7561 tcctcgtttg ctaagtaaac accttttccg tgagctgcac gtcctaataa ttcagtgaca
     7621 ttgctggcaa aagttccgcg cattccgtat acgccttcta ctttagaagc tgcaatcccg
     7681 ataattactt cgatgacttc aggagcgatc acgatctctc ctaaatcttg gtttgcgttt
     7741 aaaatcaaat ttttttcatc tgccatttat ttattcctcc ctttgcctaa gcacgagata
     7801 catccgaatt ctctatgatg cggcatagtg atcacgtggt aagaaaactg ccgccgatca
     7861 gctgcaaact gctatgaatt ggagaaaaca cccaacttta ttatctctta cagcttaaaa
     7921 gttcttctat agtgtatcat taaatcgagt gattttctat aacaaagtct gtgaacactg
     7981 atttttacgc ttacttcttc tattgatgaa actataagat gatcaattct tttggtgaac
     8041 gagtcaacac acgatttcca tcttctgtga tcaacaagtc atcctcaata cgtactccac
     8101 cgattcctgg taagtagatc cctggttcat cagtgatcac atttcctggt acaaattgct
     8161 tttctgcacg agaagaaacg tttggtcctt cgtggatctc taaaccgatc ccatgtcctg
     8221 tagaatgtcc aaatgcttcc ccgtaaccat gttttgaaat ataatctcta gcaactgcat
     8281 ctaattggac accagtcatt cctggttttg cagcatcaat aactgctaat tgagcatcta
     8341 agactatttg ataaatttct tttaattttt ccccaggatc accaatagcg aatgtacgtg
     8401 tcatatcgga aacgtaccct tcgtaatagc aaccaaagtc caatgtgatc aagtcacctt
     8461 gttcgatgat ttttttgctt gctacaccat gcggcatagc cgaacgcaat ccgctagcaa
     8521 cgatcgtatc aaaagaaaca cctgaagcgc caagagaacg catataaaag tctagttgat
     8581 ttgcgacttc aatctcagtc atgcccggtt ggatcatttt caggatgtga tcatatgcca
     8641 tatccgcaat atgacatgct ttttcgataa tagcgatttc ttcttcatct ttcacttctc
     8701 tgagttcttc gatcatctgt gaaacaggta ctaattccgc atcgatgatt tcttctaaaa
     8761 ccgaatattc taaaaatgag actgttgttt cctcaaaagc taatgagtgc agttcttctt
     8821 tgcgtactaa gtttgctacc tcatcaaaaa taggtccgac atttttaata atttcaaacc
     8881 cttgagcctg cgctgccgcc tgctcggtat aacgaaaatc agtaataaaa aatgcttttt
     8941 ccaaagtaat aacagctaat cctgtcgtac ctgtaaagtt cgttaagtaa cgaagattgt
     9001 acggactggt aaccaaaaat gaatccaaat tttcttcttg catttttttg cgcaattttt
     9061 ctacacgtag catcataatg aaactccctc tttctttgca cgcttttttc cattatagca
     9121 aacttttctt cgtacacgac agttaaataa aaatttccgg aaaacttctt tttattttaa
     9181 ataaataaag ccaaaaagga gtcacagtct cgctgcaact ccttttagtt tactattttg
     9241 taaaaactta tgatcgtttt ccaaagaaaa atgagacaac tgctaccaaa atcactgcgc
     9301 ctaaaataga tggaataagt gccatacctg cagcttttgg tccccattcg ccgaaaatcg
     9361 cttgtccaat acttgaaccg actagtccag caatgatatt cgttacacag cccatcgaat
     9421 ttcctttact ggtgatcgca cctgcaattg ctccgatcac ggctccaaca atcaatgtcc
     9481 ataaccaact cataatataa cctccttctt tgctaatcaa ttttagcata tgggatttaa
     9541 aggggacaaa taattggttt tgctatttca tattttcttc tgcaaagtaa aaaaataaag
     9601 aaaacctcct cttagaagtt ttctttattt tttacttgcg tttaaacata ctacgaatac
     9661 cacgtttcac tacatcaaag aaactcaatg attgtaccat tctatcttca tctacatatt
     9721 ctctgatcgc acgaagcact tttttaggtt ctttggaaga aaatgtgtat gtaccatttt
     9781 ttttcgtttg aatggcatat cgaggaatcc attttccctt tagcatgact gatgctagta
     9841 cataatccac ttcttcccat ggaatttgga tatatttgcg tctatctcgc gcatggtaaa
     9901 actcaaaacc attatcacct atcatgattt gcccgtaatc tgtcagaccc gtaaacgaag
     9961 tagcatcaat taccaagtct acttttgtat tgattgattg aaccattttc tccctccaga
    10021 tatttgttta tgaacagtat actatataaa aaaagctcgg gacaacgccc gagctatatt
    10081 tttatggatt ataaaagtcc gatgacgtgt ccaacaacac cgactacgaa taaaccaagg
    10141 atgataacga ttggagaaac ctttttctta agcaaccaca tacataacaa tgttaatcct
    10201 aatgcagcta aaccaggaat caattggtct aagttgtctt gtaatgttgt taccttttca
    10261 ggagaaaggg ctaagccatt attaacttgt tcaaatgcac tcttgattcc ttcaccacct
    10321 gaaggcaatt tatcccattc gatgtaagca cctttatcta attttacagt tgatacaact
    10381 ggtaagaatt tgattgatac ccatctttgt acaagggcag ctaatacgaa catccctaaa
    10441 attgaagcac cttttgttac gtcttgtaac aatccgccag aaaggtcatc agtaatttta
    10501 gaaccagctt tgtagccaaa ttcttgtgta taccacatga atgcccaacg aataatgttc
    10561 caacctaaga agaagatgat tggtccaagg atatttcctc ccatagctaa tgaagcacct
    10621 agtgcaccta gcattggacg tactgtaaac cagaacactg ggtcaccaac accagctaaa
    10681 ggacccatca tacctacttt aaccccttga atcgctacat catcaacagg cgcgccattc
    10741 gcacgttctt cttccagagc caatgtaacc cctaaaattg gagaagcaat gtatgggtgt
    10801 gtattaaaga attccaagtg acgttttaat gctgcagaac gttcttcttt tgttttgtat
    10861 aattttttga ttgctggaat catagaaaat gcccagccac cgttttgcat acgttcgtag
    10921 ttccatgaac cttgaatgaa ggtagagcgc cacgcaacag ctaaacgatc tttttttgat
    10981 aatttgattt tttcttctgc cattttattt tcctccttca agattaatag tcattcaaaa
    11041 tgtcgcctaa agggtcacca gagttgcttc cgcctccatt atttgatgaa ccacccattt
    11101 tagaaaggtt caagtaaata agagctaatg caacacctaa agcacctaga gcaatcaatg
    11161 ttaattgaga aattgcagct acaacgaaac caataacgaa gaatggccat acttcttttg
    11221 tagccatcat gttgattacc aaagcgtaac ctacagctac gaccattccc ccaccgatag
    11281 ccataccatc tgttaaccat gctggcattg attcaaggaa tgattgcaca gtttgtgctg
    11341 ggataaatag caacgctgct gctgggaccg cgatacgaac cccttgtaaa catacagcaa
    11401 tgatgtgcca catttcaacc ttacggatgt ttccttcttc agcagccgca tccatcaaat
    11461 gaacgattgg aacagcgatt gtacgtacga tcattgttaa gaacaaccct gcaacagcca
    11521 aaggaacggc aatcgcgatc gcagaaggaa cacctttaac accttgtcca cctaaaacta
    11581 aaataattgc tgatgctact gatgctaatg cagcatctgg tgctacagcg gcaccgatat
    11641 ttgcccaacc taaagcgatc atctgaagcg taccgccaag tacgatacca gcttcgaggt
    11701 taccggtaac taaaccgatc aatgtacatg ccactagtgg ttgatgaaat tgaaattcat
    11761 caagaatacc ttccatacca gctagaaagg caactaatac gactaaaatt attgaaataa
    11821 tagacatgat aagcctccta taaattttaa tattatttat tacgcttttg ctaattcagc
    11881 ttttgctttt ttcaaaatat catccatgtt atcgcgtgaa tcattaggta ctttacgtac
    11941 atcgaatttc acaccttttt gttcaagctt ctcaaacgct tcaacgtctt cttgtcccat
    12001 agacaatact ttacttacaa cgactttacc gaccgaatgc gccattgacc caacatttaa
    12061 ttctttgatg tctacgccac cttcaacagc tgtcaatacg tcttcaggat tttcaaataa
    12121 aagcaatgct ttggtatttc caaaacgagg gtcttttgct acttcgatca ttttgctaat
    12181 aggaataaca tttgctttta cacctggagg agcagcttgt tcgattagtc tcttacgcag
    12241 atcatccttt gatactgcat ctgaaacaac gataatacgg tttggttgca ctgcttttgt
    12301 ccaagctgtc gcaacttgtc catgtaacag acgtgagtca acacgtgcta atacatattt
    12361 gatttttccg tctccgacca cagttccttc tggaagtgct cctttaggtt gtgcgtcttc
    12421 aactgctgct ttcggtgctt ctgccggttc taattcttcc ggttttactt ttacaccgtc
    12481 ttttgctgtt tcaatgatgt gtgctgcaat ttcatgagca gattccattg aaaagcgtga
    12541 tgcgtaggct tcaatcaaca ttggtaaatt caaaccgctg acgattgccc atttatcttt
    12601 gtgctcttcg aataatgtgt ttgattgatt gaacggtgtt ccgccccata aatcaactaa
    12661 gaataacact tcgtcttgat tatcaaaaga agcaaccgct tcttccaatt tggctctcaa
    12721 gtcatctgga ccttcacttg gtttcaaaat cacggctttg acgttttctt gttcgccaaa
    12781 gatcattgaa ccggattgta agattccttc agcaaattgt ccatgacttg ctaggataat
    12841 ccctaccata tttatacctc ctatttactt ttgttgtaac aaattcaaaa atattaataa
    12901 ttgctaacca ttacaacaga attatttgac cttttccaac aaccattctt gctacacctt
    12961 tttgattttc gctagtagtt ccatcaaaag gattttcctg tcagcaggta cttttcgaat
    13021 ctctaactcc acttcttgac tgttcaagta acgaaaggaa tcaatatctt gttgatttac
    13081 tgaaacaaaa ttggtaatca ttgatttgcc ttcagtaaaa ctcataccgc cgatattcaa
    13141 cgacttcaac tgtacaccgc agcggacaac cgcttcaaca tcttggggat tggtgaataa
    13201 aagcatcact tttgctcgtg ataataatcc actatgatag atttgaatca ttttctgcac
    13261 ggttattaca tttgctgtga tccccggcgg tgcagcttct tttagtagaa actttctcaa
    13321 tttatcttga gcgactacat cgctgatcac aatgatacgt tcaacacctg tttgcttcga
    13381 ccaaactgtt gcgacttgcc cgtggattaa acgatcatct atacgtgcca atcgaatatc
    13441 catctgcaaa actccttctt cctcactact tcacagaaac ccctatcatt tctgtgtgaa
    13501 caaccacctc ctagcacaca ctactataag caaaaagcgt gccaactttt ttacgataca
    13561 ctaattgaat ttaaaggatt cttaaccaat acacaaaaac gatacactat aaaagtgtat
    13621 cgtttttgtg tattcatggc acagtgtatt cttttttatc taactgatta tggactagac
    13681 gtagcagata atacatttct tctatcggca cttttacttt tatctgatct tccaacagaa
    13741 caactgaggc tgccaattgg ctataaagag gatcattcgt tgtatttgtc aattcgtttt
    13801 cttccacagt caatggttca ttccgaataa tacgttcgat cattcctgct gtgtgcatca
    13861 ctaggttgat tttgaatcca tattcttcat cgccgattcc cgtcgtctga gagatttgtg
    13921 tagaaaattg ccacattgga tcgattaact tactaccatt aataaagatg aagttatcag
    13981 agataaactc aacacacgta tttttagctg actcttcatc tagggagatg aattcagttt
    14041 cctccaattc tgattccatc agcaactgat ccaaaatgac ttcgatattt tgatcaataa
    14101 aacgttctaa aggaataaat ggggcttgga tattcaaatc agtaatccca gtagtagcta
    14161 tgatctgata ttctttttgg ataactggca gttcttcttt cacttccaca atcgacaaag
    14221 ctagaacttc taattctgtt tcttgacgct tgtttaccgc tcgttcgatc aattctttga
    14281 ttctttgtgc tgtaccttcg ccagatgcgc agatagccaa aacagctttt ttcttatgaa
    14341 taggttttgc ttcctgaaca gattctacag aagatatttc tgcgtaacct cgaaaatttt
    14401 tcaatgattc atgcaacata tctagatctg tccctaatac tgagaccttt cgtacagttt
    14461 ccaaaactag agaagttgtt accatatcaa cagtacgtac tggaattcca gtgtctcttt
    14521 gaatttgcga attaaacgac gcaagggacc ccatatctac taagagtatg accccgcttc
    14581 cttcatctac ttcttgtaca ttgcgttcaa ttcggtccaa tgctgttttc ggatccatat
    14641 ccaaaggcat gtctactgct cgtacgttct ctgcatctaa caactgttgg acaacttgga
    14701 ccatactgct tgctgtgctg tttccgtgag ctgcaacgac tacaccgatt ctgccgcttg
    14761 cttgatttgc ccgtaacgag acgagtagaa cggtcaagta atagtcttca ctttctggaa
    14821 tctccacttg aaaatacgtt tcgatataac tacgcacttc tttcgcaaca gcatattcat
    14881 ctggaaaatc aaaagccatc tcacggatgt tatcattcgt atgccgttct tctcctaagt
    14941 tgattttttt caaaaaagaa ctgatatgca agctcatagc ataaataaag ttttgctgaa
    15001 actcatatgg taaagatctt ttgaccatta cataaatctg attggtcact tctatgattt
    15061 tcggatctac aaattctgct aatttgctgt ctgcattaaa agaaaaacca tggtctttat
    15121 agaaagactt cagatggatg ttgatatctg tagaaatgaa atgattgatt gcttcttgat
    15181 ccaaaccatc cgacttcagt aaagctgctt tatctccgat gatatcatat agattataag
    15241 gtaactcata ggagtccgat tggattttca tgatcgtatc atttggtgct acagttatct
    15301 ttggctccaa tattttagaa agctctgcca ttgcactgcg gttgcttgct aattgaatca
    15361 atccgctacg aatcccttct gtcaaatcat cgattgtgat cgagatttcg ggtgattgca
    15421 tatgatttag aaatcctcgt gcacatacta actggatatt tgacttcaat tgtcctatat
    15481 ttccataggt cacactgccg atcaatgctt ttgctacatc ttctgtcaaa gaaatctttc
    15541 gctgcgtgcg gtttgcttcg tgggcaatca tgatttttac taaatcgact ttctcatttg
    15601 caggacgttt ttcaaaagcc ggaagtttga tattgattgg gatacgccga acaaaagttt
    15661 ctaatagaga agaacctggg tcttctgtgg tcgcacctac gatccgtaca tttgcttcat
    15721 gggatttcgt tgtttcccca agacgactgt aagttccatg atccataaag taaaagatca
    15781 tttcttgacc ttcaggcggc aaccggtgaa tctcatccaa aaacagcata ccgccatccg
    15841 cttgatcgat aatccccatt ttttcttcat ctgcgcctgt aaaagcacct tttgcgtacc
    15901 caaataaatg actcatcaaa agctcagggt tattggcata atcagcacaa ttgaaaacaa
    15961 tcagttccgt ttcctcatct attacatgat gcgcttttgc aaaatgatac atcgcgtgtg
    16021 caaaataagt ctttcctgat ccggtaggtc ctgtaatcaa acaatttaat cctcttggcg
    16081 gatacaaaat cgcagctttt gcctgttcca ctgaattttt catgctgccg ttagctccaa
    16141 tgatttttgc aaagatatcc ttagtatcta tttggagtgt atttttttct tcagagaccg
    16201 gcgtttcttt gtaactgact acatgttttg taactggctt tacgtgcgta acgagtgttt
    16261 gatatatgta acgtactggt cgtccgtctg tctttatcag ttttccttcg cgcactagct
    16321 gattcagatc tttactgcta tttgttcgct gaatccctaa cacttcagca atttcctgtg
    16381 ttgttactcc ttgatcatat tctgcctttg ttaaatgagc ggttttttct ttgacataca
    16441 tataaattcg gtcaatgcgt tttgccaatg gtatcgctcc ttttctatag actattgtac
    16501 ttaggcttca aaacataata ctatgtattt atttctgttt cgtcaactat ttacctgatt
    16561 ttgttttgtt gataacacgc ggatagatag aaatgttcaa tttaaaagaa cgaaaaatcc
    16621 cgatacgatt tttataatgg aaacaagaaa aagaacactg tttaccatat aattatttca
    16681 ctgatagcaa acaatatagc ttccatcaat tgaaaacgat agttatcaaa acatcctgat
    16741 tccaaattgg caaaaaaata ttaagtgtaa aaagacaaag taaacttcgt agcctccact
    16801 acaactttta tttttataaa caaaaaaggc tgtgacaaaa gtcttgtcac aacctcttta
    16861 atcataagat tcaattaagc ttcttgagct actggataaa cagacacttg ttttttgtta
    16921 cggcctttac gttcgaaacg tactacgcca tcaacttttg caaataaagt gtcgtctcca
    16981 ccgataccca cgtttacacc tggatagatt tttgtaccgc gttgacggta aagaattgat
    17041 ccacctgtaa ctgtttgtcc atcagcacgt ttagcaccta gacgttttga ttctgagtca
    17101 cggccgttag atgtagaacc gccacctttt ttgtgggcaa ataattgtag attcatagat
    17161 aacaacatgg tctgcacctc ctatttatca ttaattgttt taatttggat atattctgag
    17221 ttttcagctt ctatcgattg taatcctaat aaaagatttt ctaatagaat ctcagcaata
    17281 ttgttttgtt cttgtgtcat tcctgaagtg acttcggtat aaagataacc gccttcttct
    17341 tcattcattt caacaatcgg ctcaaaaccg gctaatgagg caatcccgtt gacagtgctg
    17401 atcgctaacg cagaaacacc cgcacaaacg atatcacttc cataaggacc agcatcagca
    17461 tgcccggtca aagtgaatga aacgatctga cctgcgtcat ttcgcttaaa tgttcctttg
    17521 atcatatata ggccttcttt ctcaaacgct attaagcgtt gatcgcgtcg ataaccactt
    17581 ttgtatatgg ttgacgatga ccttgtttac ggtgtgaatg ttttttaggt ttgtatttga
    17641 aagtaacgac tttcttttgt ttgccgtgtt tttcaacagt accttcaaca gttgcacctg
    17701 caacagttgg agcgcctact tttgtagatt ctccgcctac taagataact tcgtcaaaaa
    17761 caactttttc tcctgcttca acgtcaagtt tttcaacata gattgcttgt cccacttcaa
    17821 cttttacttg tttaccacca gttttaataa ttgcgtacat gctataaagc acctccttct
    17881 gatatactta gactcgccat ccgaagtgac agcatatgct gtgcttatta cttgttctga
    17941 gcggttgtag ctgtggagtc cacaattaca acagtactag cttaccagaa cagcaaccgt
    18001 tagtcaacta aatttaaaat caaaaagtaa aacaaaaatt caagcaatac ttctgctttt
    18061 ctatcctcac agttctacca aataaaatag tcgcattgtg tttcttttat tcttataata
    18121 aaagaaaaag gaggagcata aatggaatac ccaaaagaac tgatacaaga agcttcttta
    18181 agaatgaacg gccgtcctgt agaaggattt atcgctgggc aaggacctct tcatcctaaa
    18241 ctgatgctcg tgggagaagc cccagggaaa acagagattg atacgcatgt tccttttagc
    18301 ggtcaagctg gaaaagaatt gatgcaggca ctttcttcaa ctggcttaac acgagaagag
    18361 gtgtatatca ccagtgctgt aaggagccgc ccgtatcgcg tgactcatcg gatcaataaa
    18421 cggacacaac agtcagaaac tgtttatcca aatcggacac ctactcgttc cgaagtattt
    18481 gcgcatgcac caatattgga ttacgaactg atgaaggtcc agccaaaatt aattgcgaca
    18541 cttggaaaca ttggtcttca acgtttactt ggcaaagaat atacggttac caaaaatcat
    18601 ggtcaactct atacagggcc tgtcttacaa ttaacagaac aaaaggatgc ctacgaatgg
    18661 tcagaaaaaa actatcgaat tcttccactt tttcatccag cagctatttt ctacaatcgc
    18721 tcccttgtac ctgttatcca tcaagactgg caagtactag cttcactttt acagcaatat
    18781 taaaaagaac agacaagacc ataaaatctt cagtttacag tcttgtctgt tctttttcat
    18841 tgttttaatg gctaattgca gtatatttcg catgtaaagc tgtcaacgca tgagcaactg
    18901 tttgatgttg atgcgtgaat gtatgttccc acaagtgaga aagttgtttt tctacttctg
    18961 gctgcaagga agtatagata atcgtttgtc ctctttgctc tgctttttct tgaaattcat
    19021 caaaaactgc acgtgccgtc aaatcaatac ttggtacgcc tcgcatggag aaaatgacac
    19081 catcgtgatg atttagttct tccaatttat ttttgagttt ttctgaagac ataaaaaaca
    19141 gtggaccact aatatacact actgtccagt tattcagctt ttccgtttct ggcagcccca
    19201 ttctttgcca atcgatcgtt tctaatgaaa tcgtgatagc agcgcttttg acaacaaaaa
    19261 atacacagcc gccgatcacc ccgatcacga tagcaatact taaatcaaag ataactgtac
    19321 aaatcatcgt aaggataaac aatagaactg ctgaccaata tttattagta aatagctcct
    19381 tgatcgtttc ccattcattc atacgccaag ccgtcacaat caaaacacct gcaagtgctg
    19441 gcattggaat ctgtgacatc actggcgcaa aaacaagcat ggagagcagt aagacaactg
    19501 catgtatcat accagctaat ctagtttgtg caccagattt gatggccacg cttgtacggg
    19561 cgatggccgc agtagcagga atcccgccaa agaaaggaag caacagattt ccaattcctt
    19621 gcgccattaa ttcttgattg ctatctaagg gcttatttgc cattcggcca gccgaagcac
    19681 cacatagcaa gctttcaatc attcctaata aagcaatgct aatagctgga actgccactt
    19741 gttgcaaggc agaaaagcta aaatctccca tattcaaacg attactactg atcaatgttt
    19801 gtggaatctt acccacagtt gctactggta aatggaacaa tagcataact gctgttgcca
    19861 aaatgatagc cagcagcgaa ctaggcattc gtttcgccca tttttttgga tagataaaca
    19921 tccctaaaat gactagccct cccatgatca aagaggctgt gtttatcgga aatcctatcg
    19981 tttgataact acttagtttt tcaataacgt ttgtaccttc cgagtgaaca ccaaataaat
    20041 tatcgatctg acctaatgca ataatgatag caatacctga agtaaacccc gtaattacgg
    20101 gtgctgggat aaaagaagtc agtgttccta atcggaaaag tcctgctgca agtaaaaata
    20161 gacccgctaa aaaagtagca agcaatacac cttgcattcc ctttgttgcc gcaatagaca
    20221 tcaagatagc tgccatcgca cctgtcggac ctgatatttg ataaaaaccg cctgataaac
    20281 cgccaataac gataccggca atgatagccg taatcaaacc tgcggccgca tcagctccgc
    20341 ttgatacccc aaaagccaag gctaaaggca atgctacagc agctactgtg atcccagcca
    20401 aaagatcttt ctgaaatctt gaaagatcat aacctgaaaa ttcttttttt agtgaggaaa
    20461 cataattttt gaacacctat ctaactcctt tttcatgaaa ttttctaaaa taccattcat
    20521 tagaatatca tatttcatga gataaagtaa tatttttcac aaagtttcct gttagataaa
    20581 ttcttatttt ttctatattt ataagaaaat agaaagcaat gccaacagag ctagcccacc
    20641 ttgtttgagt aaaatccaac gatcgctagt caaactgcca tataatgcaa caaaaaaaat
    20701 agatattaat agcatacttg tgatttcttt agatgcggaa gaaagataag ctccataaag
    20761 tagtcccact cctaatagtc cattgtacac tccttggttc ttaaacaatg tttgaacaga
    20821 ttttctgctt aactcttctt tactcatttt aaaaacccta cttgtcgtgt cagaatcagt
    20881 tctcaccgtt tcgatataca tgatataaaa aaattcaatt gcaactagag tcactaaaat
    20941 tctagatagt atcgtcatat cttcttcctc ttttctgatg agttttattt ttttgctcct
    21001 tataattgta ctcgataagg atgttttttt attttatttg cctttgaaaa caaacaatat
    21061 tggcacaaaa aacaaagaaa aaccgttaga aacctcagtt tctaacggtt ttttagcgtc
    21121 acaggaggga ttcgaacccc cgaccgtccg cttagaaggc ggatgctcta tccagctgag
    21181 ctactatgac aagaatcagc ggaacatcaa taattataga taattaaatt gcttctgtca
    21241 atacgaaata gttatttaat tagcaaataa tgaattattt tggcccaact actaaatcaa
    21301 tcttttaaaa cgagacattc tccttcagct gttctaaggt tatcaattga aaacaggagc
    21361 tacattgact tcatgctact cctgtttatt tagatttcct gtatccttta attgacttac
    21421 aaatatagaa acttttacat caagttcgaa ttgagccctc gattcaatcg attatctaca
    21481 ggctgccata atcatgtatc acaactcgat tgtttctgat tcctttgtca ttaagatcac
    21541 accatcacct aatggcaaga ttgtcgatgt caaatcggga tgatccatca caacacgaag
    21601 aaattcattt aatttacgat ggatagctcg tttgccacgg ggaatctctt catctgggag
    21661 caagatcgtt cctccttgga agatgtcatc taccatcaaa acgccacctt ttcttaacaa
    21721 acgtaagcat tcaggtaaaa attcaatata ttttgatttt gcactatcca taaaaataaa
    21781 gtcatacgga ccagacaact ccggcaagat atctgctgct tgaccttcaa gcaaagtcac
    21841 tttatctgtc agtcctagac gttcatagtt ttttttagct ttctcgatca tgacatcgaa
    21901 acgatcaatt gtcgtaacat gagcgttttc tccgattgtc gtggccatga cacttgatga
    21961 aaaaccgata gctgctccga tctccaagat tcgttcaggc tgaagctgtc caagtaaaaa
    22021 tttcaaaaat acaactgttt catggggaat aactggtact tctgctacat gagcttcttc
    22081 ttccagtttg cctagctcac ccggtaattt tttttgctgg gtacgcataa aatccaatag
    22141 ttcttctttg actacaggac gatgcatcat ttcattgcgc atactactcc tcctcttcac
    22201 acattatacg aacaactgac taaatctaca agctgcatga gtgttttctc gtgtttcatg
    22261 ttcagaagag tcgttggatc tctggaatac atttatgttt ttaacattct tacaaaaatt
    22321 tctgtgttcg tctccgcttc tttttcaact ctacaaaggt attccatgct gtgattcctg
    22381 ttaggcaaaa agcaatcgta aagaataacc cctgaatcca tgcaaatgcc gtttttgaaa
    22441 ggactagtcc aatatatgga atctgaaaga tgggactacc gataatattt ctctttttta
    22501 ctactccagg ctcaatataa gtctttgtat cagcttttgt ataaaaatct tcgtggttgt
    22561 tttcaacggc tattacgcga cgcgtcgaga ttttttttcc tgaattttca taatatgtaa
    22621 taatatctcc gactaaaatc tcatttgtat ttttcggtcg tacatatatc agatttcctt
    22681 gtgcataata tggactcatt tctttgtcct caataatata aggagtcaaa ccaaaaattc
    22741 ggggaaccaa gacgacgaga agaataagaa ttaaaaatat aatcaacgtt atagaactta
    22801 taaaagttat ttttttgtaa tcaggtatcg ttttcaactt ctttctttat tcaatccttc
    22861 ttaatcatat aataacg
//
LOCUS       DACDAF010000045        22323 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.045, whole genome shotgun sequence.
ACCESSION   DACDAF010000045 DACDAF010000000
VERSION     DACDAF010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.045"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            2..400
                     /locus_tag="IVZ69_001588"
     CDS             2..400
                     /locus_tag="IVZ69_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HAP8183674.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            384..1079
                     /locus_tag="IVZ69_001589"
     CDS             384..1079
                     /locus_tag="IVZ69_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HAP8183675.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1673..2560)
                     /locus_tag="IVZ69_001590"
     CDS             complement(1673..2560)
                     /locus_tag="IVZ69_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rotamase"
                     /protein_id="HAP8183676.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2745..3584
                     /locus_tag="IVZ69_001591"
     CDS             2745..3584
                     /locus_tag="IVZ69_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HAP8183677.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3780..4754
                     /gene="sgrA"
                     /locus_tag="IVZ69_001592"
     CDS             3780..4754
                     /gene="sgrA"
                     /locus_tag="IVZ69_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HAP8183678.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5052..5408
                     /locus_tag="IVZ69_001593"
     CDS             5052..5408
                     /locus_tag="IVZ69_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183679.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5411..6568
                     /locus_tag="IVZ69_001594"
     CDS             5411..6568
                     /locus_tag="IVZ69_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183680.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6594..7034)
                     /locus_tag="IVZ69_001595"
     CDS             complement(6594..7034)
                     /locus_tag="IVZ69_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP8183681.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7194..7700
                     /locus_tag="IVZ69_001596"
     CDS             7194..7700
                     /locus_tag="IVZ69_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP8183682.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7868..9780
                     /locus_tag="IVZ69_001597"
                     /pseudo
     CDS             7868..9780
                     /locus_tag="IVZ69_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
     gene            9785..10786
                     /locus_tag="IVZ69_001598"
     CDS             9785..10786
                     /locus_tag="IVZ69_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP8183683.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10988..11194)
                     /locus_tag="IVZ69_001599"
     CDS             complement(10988..11194)
                     /locus_tag="IVZ69_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HAP8183684.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11840..12688)
                     /locus_tag="IVZ69_001600"
     CDS             complement(11840..12688)
                     /locus_tag="IVZ69_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP8183685.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12852..13754
                     /gene="gnd"
                     /locus_tag="IVZ69_001601"
     CDS             12852..13754
                     /gene="gnd"
                     /locus_tag="IVZ69_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HAP8183686.1"
                     /translation="MEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDI
                     PAYQEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSI
                     RRAEEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLY
                     AGASGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWL
                     MEIMEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEED
                     SFSAKVVSALRNGFGGHEIVEKGE"
     gene            13756..14757
                     /locus_tag="IVZ69_001602"
     CDS             13756..14757
                     /locus_tag="IVZ69_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP8183687.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14754..15038
                     /locus_tag="IVZ69_001603"
     CDS             14754..15038
                     /locus_tag="IVZ69_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP8183688.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15071..15868
                     /locus_tag="IVZ69_001604"
     CDS             15071..15868
                     /locus_tag="IVZ69_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP8183689.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNAAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15882..16715
                     /locus_tag="IVZ69_001605"
     CDS             15882..16715
                     /locus_tag="IVZ69_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8183690.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16733..17590
                     /locus_tag="IVZ69_001606"
     CDS             16733..17590
                     /locus_tag="IVZ69_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP8183691.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLMQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17612..18121
                     /locus_tag="IVZ69_001607"
     CDS             17612..18121
                     /locus_tag="IVZ69_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8183692.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18158..18559
                     /locus_tag="IVZ69_001608"
     CDS             18158..18559
                     /locus_tag="IVZ69_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183693.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18671..19024
                     /locus_tag="IVZ69_001609"
     CDS             18671..19024
                     /locus_tag="IVZ69_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183694.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19058..19501
                     /locus_tag="IVZ69_001610"
     CDS             19058..19501
                     /locus_tag="IVZ69_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP8183695.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19518..20603
                     /gene="uxuA"
                     /locus_tag="IVZ69_001611"
     CDS             19518..20603
                     /gene="uxuA"
                     /locus_tag="IVZ69_001611"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP8183696.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20596..21309
                     /locus_tag="IVZ69_001612"
     CDS             20596..21309
                     /locus_tag="IVZ69_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP8183697.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            22061..22261
                     /locus_tag="IVZ69_001613"
     CDS             22061..22261
                     /locus_tag="IVZ69_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP8183698.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
BASE COUNT         7686 a         3431 c         4624 g         6582 t
ORIGIN      
        1 gatgacgatc tttgaaacgg ttgtaacaga tgttggtata gaagcagaag tattcaggaa
       61 agaaaaaata atgattttat ttggagatga agcaccggaa acattaacag attattgtta
      121 taagattgaa ttgaatcagg taagaaaaga aataacttgt gatatgaagc tctgttttga
      181 taaacaaatg tatgtaatca cagcagtagg agatgttgtc caaactaatt tgaatgaatt
      241 aggacatatc acgataaaat ttgatggatc tcatgagccg gaacttccag gaacaatgta
      301 tgtagaagat aaggaaatgc cgcatttaag aaaggggaca atcattaaaa tcgatcaaga
      361 ggatcagaat gggggaaagc tatatggaaa tcatgcttga tacagcaaat acaaaaagta
      421 tttattcttg tcaacagttt ttgaatttaa caggcgtaac aacaaatcct acaattctga
      481 aaaaagaagg agcgtcaaac ttcttctcgc atatgaaaga aatcaaaaaa ataatcggac
      541 agattcctat ccatattcag acaataggaa gaacggaaga agaaatgata gaggatgctc
      601 gagttatcat agaagaactg ggaaaagata cgtttatcaa ggtgccggtg aatcaagcag
      661 gccttcaagc gatcaaaaag ttgaaaaaag aaggttattt gattaccggt acagctattt
      721 acacagaatt acaagggtat ttagctatta ataatggagc agattatatt gcaccttatt
      781 ataacaggat gcaaaatcaa ggcattgatg ctatgaaagt gattgattcg ttgcggactg
      841 agatcgaacg tacgcaaaga ccaacaaaaa tattagcagc tagtttcaaa aattgtgaac
      901 aagtcactac agccattcga tctggagctc atgcgataac gttaggtaaa gagctactag
      961 atcaagtatt agagatgccc tcgattgata aagcagtgag gggcttccaa gaagattggg
     1021 tgcaaacttt ccaagcagaa acgattggtg aactaaaaaa ggtcgctgat tacttctgaa
     1081 tcaatttctc cataaaataa acgatagcct tctcgaaaac tcgaggaggc tatctgacga
     1141 ttcaatattc attaatttaa agtttgggtg actattacta actattactt atttctcatt
     1201 taaacgatgt attccctaac ctctaataca tccttgtaac tctgaagtta cgccagtttt
     1261 gaataaattt cataaaaaca aatgaaaagt gtcgcataaa aatatctttc gtgtttctct
     1321 agtataacag aataagaaga acaagtccag aagggatatt tttagtcttt tttaaaataa
     1381 cttttcagtc gagtttgagt ttatgatagt tgtttttgaa gcgatacggc aagtgaaaaa
     1441 atagggaagc atgaaagaat ctacttaatg gcgcattgat tcatgtgata gaaataaaaa
     1501 acttttttaa attatatcct catgattgta acaaatccag tgatttgttt tggtacaaat
     1561 aaaaaaaggc cccgatgaag ttgtggcaaa agtggtttgc ctcaaaaata agaaggaatt
     1621 tccaaaaatc acttctcaaa ttttgccaca tccccaattg ggtcaaattt gtttatttga
     1681 atatattttt tacataagga tctttaatag ttacattgtc ttttttcatc actttacgga
     1741 ttgttttatc catgaattcc gtatcaagag tttttgcttc ggtagcaatt ttttctagct
     1801 cagatttgta tttgtcttta ttagaacctt tatcctgttt ttttaccatt tttactagat
     1861 aatagctttg ctgataagtc gttggatctg ttacaggaat gatatcagaa acttccccgt
     1921 tttttagttt aaatgctgct ttttttactt cagtaggaat ctctggattg gttgaatcaa
     1981 aattcatttt tccatcagtt tcctttaatg ttttattttt tccataagct tgaacaagct
     2041 tggagaaatt ttctccttca tttgcttctt tttttgcttt atctgcttct tctttagtcg
     2101 aaaatagaat gatctgtgta ctaacttctg gatagaattc tttccaagca gtgtctagat
     2161 ctttatctgt taattttaca ttggctttca aaccgtattg gaaagccagc atctgtttaa
     2221 agagtttctt atatgtctct tctgtttggc caactgcttt taattgttcc ttgtagtttg
     2281 gaccgagttt tttgatttgt tcattatatt cttttgttac ttcctttgaa gaaatctctt
     2341 ttccgtatac atcatcaaat gctttgaaga caatcatttt ttttaatagt gtttgattat
     2401 ttgatttaac ttttgggtta tcataaaaat cctgaactgt aagtgttcca cctttaaacg
     2461 ttgcaatcgt ttcattggac ttgctacaac ctgagaatag taaaattgca catgctgaaa
     2521 ggcacataat tagtagttgt tttttcaaaa aatttcccat cctttcctta ttaaaaacag
     2581 tctaacagaa gaattaggga gacagtcttt cattttcgta aggttgctgt agatattctt
     2641 agttcgtaaa aatctattct ctctatgatg gagaacattt acatagtttt cacgagacaa
     2701 gaaagaaaag ggttgttaaa cttaatataa aggagggatg aaagatgatc aggattattc
     2761 ggttgattgg atctgtttta atagtcttag ttggttttgt tttaggaatt cttgtcaata
     2821 atgcacttgc ggatatgttt attggaaata gtgaatggat tggagcaatt gccggtacgg
     2881 tcggacattt agctgttttt ttactagctt tatttcttgc tagtaaggtc gaaggaaaaa
     2941 gaatagaaga ttatggtgtt tctgttcgag gaaaagactg ggggtattta gcgggaggtc
     3001 tcgttgttgg aattggagtg tttctgctta ttactagtcc attatatttg acgggggcgt
     3061 atcggttaga ttcaggaaac gcaaacattg tgccgctgat aacgagtttt attttattta
     3121 ttgcagtggg ggcatcagaa gagcttttat tccgtggctt ttttcagcat cagatgctta
     3181 gatttggtcc gttaatagca atgattggat ctgctgcatt atttgctctt ttgcacggat
     3241 tgaatcctaa catgacattt ctggcagttt tcaatatctt tttagcaggt tgctttttca
     3301 gcgcacttat ctacagtaca ggaagtttat ttacggctat tggtgctcat attacttgga
     3361 attggacaca aggagctatt ttgggtatac cagtcagcgg aacgcaagaa caaggttttt
     3421 tctccactct gatccaatcg caaaatacaa taattactgg gggaaacttt ggggctgaag
     3481 catctatatc aactacatta ttcttgttag tcttgattgt tggtttgtta ctctatgcat
     3541 ataaaacaaa gcggatgaag aaatacactg ctgtttatca ataaaagatg aagaaagcaa
     3601 ggctgatatc ggtcttgctt ttttaagtct gtcattgatt aaacgaaaaa gtaaacaaat
     3661 tcaagcgaat acacgacatc ttttgttaga ttttcacaac tgactgtcgt gttctcatca
     3721 ttttcatttt atataattcc tttatcaaat agaaggtaat tatatggaga gtgatagaaa
     3781 tgaagaaaac agcgaccgta ttatttgtta ttcttgggct gagtataatt gcagcaatga
     3841 ttggaatcag tacttctgca aatgaacggg caaatgagaa tctttcattt actgtgaaaa
     3901 ctgatcggat tgtttatgac atgacacaac aagtcattac tattccagtc aaaccaaaca
     3961 aaagcgtgaa tgctagtgat gtacatgctg ttctaacata tggttgggat ggtaatggaa
     4021 gttcagaaaa agttattggg gaagtttatt taaaagacgt acaatggacc gctggtattg
     4081 agtatacaat aatgatttct gcagaactat cgattgatga gatcaagagt aaagataaag
     4141 ttgatttgat tgttttttat gatggacaga tgacgatcac ggagaatttg aaaccaagca
     4201 gttggacagt tgttggaccg ccaagcagta cggatagcac aagtagtgaa agcagtacag
     4261 aaaacacgag cggtgaaagc agtacagaga gtacgagcag tgaaagtagc acagaaaaca
     4321 cgagcagcga aagcagtacg gagagtacga gtagtgaaag tagcacagga agcacgagca
     4381 gcgaaagcag tacggagagt acgagtagtg aaagtagcac aggaagcatg agtagtgaga
     4441 gtagcacagg aagcacgagc agcgaaagca gcacaggaaa agtaaataat gaacttgatt
     4501 tggtacctat cataccaact aaggaacaaa agagaaatgc agggagcaac ctaaaaagtg
     4561 tgctaaaaca gcctgatttt gtttctcgtg gaattgatca tcaagaaaaa gcgaaagaaa
     4621 cagataatag aaaaagcgat ttaccagaaa ctggtagtag aaccttgaac aagctaatta
     4681 catggatggg tgtgttactc attttgattg taggagcaag ctattttcgt tctctcttcc
     4741 atcgagtgaa ataaagaata aaagcaacag atctaaaatt gaataaaacg atagattttt
     4801 gagtgaatat ttcattcgag agtgctgtat tgcctggcga agttgtagct ttgccagatc
     4861 tatttttgtt tactaacata tttgagaaac aggaaataac aggaacacaa atggaaaata
     4921 agagcaagaa taattgacaa tgcacactgc gcatggtagt atctctgaaa aatcagtaac
     4981 gaatctattt gtacgttatt catgtagctg tcggaataag tctaaataat agataaaaag
     5041 gagtatgtac tttgtttgaa gaatttattg atatcaatga aaggcaagta tatcaatttt
     5101 tgaactattg ttatgaaaga gacgagaaat tatatgtggt gaaggatatc gctttagatc
     5161 taaactacac cctggctaag atgaattcgg tgattcaaca agcagaatcg ttttgcgaaa
     5221 ggtatccaga atataaatta tcttttcttt cagaaaacaa gatgataaaa gtcgagtttt
     5281 cttctcagtt tttactgagt aaagtttatt ctatactttt agagggaacg attggttata
     5341 ttttactgga ttcactttac aaaggtactt atcaatcctt agaaaatctt agtcaaaaaa
     5401 ttatataagt ttgcgtacga ttcaaagaaa attaagagaa cttaatacta ttttgaaaaa
     5461 ctatcattta tcttgcagct tgaaaaaagg taatccgata gaaggagaag aataccgtat
     5521 ccgatacttt tttcacttga tgtattggca gtcattcgac gaaaatcatt ctgatatatt
     5581 atcaagtata aaaaataaac gtcaactatt agaaaaattt gcgaaacatg cgccatatac
     5641 gcgtagtata gatagaaaga aatggatcag cctactaaga atttcgttgc aacgaatgaa
     5701 acaaggccac tcgattacgt atgtcccaga agagatgaac aaatttgtgc atccattgat
     5761 aacaaaagaa gagtttacgc attacatact agagcctttt tttgaagcaa acttctggtc
     5821 gatgaatcac atcactccaa cagagcaagc ttacctttat tttatgtttg gtgtaatgaa
     5881 cacctatttg gaagaagatt tgttggatac tccagataaa gtacaagaaa gttggggctg
     5941 gattgaatcg tctattgtag aaaattttga aaaaaacttc aagatttgtt ttacaacttc
     6001 agaaaaaaat tatctatatg tcaatttggc aatgatccat ttgtattcaa gggtttttgg
     6061 gacaaaaaag aaggtggatg cttttggaaa atcagcagaa gacagagatt ttcagcatat
     6121 atttccagtg atgtatccaa tcatgcaaca gttttttagt ggggtagctc gcagaattcc
     6181 agagcttaat acttattatg aaaagaacag acggttgatt tttcaatact gtatgttagt
     6241 cagggatatt tttataaaac acgaacaacc tgtcatattc tatattcaat caaagtatgg
     6301 taaaacacag gaattatggg caaagaaaag gatattatct atgactgaac gcccaataaa
     6361 atatagtgca tccgctgatc agttacctga tattgtcatt agcgattatc ctatcgacaa
     6421 aaaggcatat gatcaaacga atacacagat attttactgg aatggacaac ctacaaaaaa
     6481 tgattgggcg cgtctgaaag ctgaaatcat aaaaatcagg aatgagaaaa atagatccat
     6541 attggaaaaa ttggatttcg ttaattaaga aaagcagatt gtttatgcca aaattaagac
     6601 attgcaaaaa gattattttc tttaaaatcg acaagatgac cagaaagcaa gagttcgttg
     6661 agctcttgct ttcttttagt tttagaaagg aacatcctga ttttatcttc gctaaatcca
     6721 gtcaaaagtt ttgcagattg gtcgtagata atcggttttt tcaataaaga aggggatgta
     6781 cgaatctcaa tatatagttc actcaaactg agttcatcta ttctgtgaac aagattttta
     6841 taactaatag aatgagtaga gagcatttcg gtcacgccgt tgtttgtcaa ttttagtaag
     6901 tggataaatt catttttggt tagtggttga cgaattaagt tctgttcgat aaacggtata
     6961 tcatggacga taagccaacg ttttgcgcgt cttgaagacg agcagccaga acctgtatac
     7021 aatttaatca tcatacattc ctccaatagc taagtattta tgaaataata acatgaagaa
     7081 atagtcgaaa agtgccattt agaggtgtaa aataagaaaa tgttgtcacg tataatggaa
     7141 ctagctagat aagaaatact attaaatcaa gaaaaaagaa agaaggcaca agtatgtcaa
     7201 acacagccga cgcaatagta gtgatcgatt tacaaaaagg ggtatgtttt gattcttcgc
     7261 cgatacacga attagaaaca gtgacagcat tagtgaataa aagaatcaaa acatacgaaa
     7321 cgattgggaa accagttatt ttcgttcaac acgaagatgc tcaattagtg ccacaaacaa
     7381 aaccatggga gctattgtcg gaattatcta ttcctgagca cagttatttt gtgagaaaaa
     7441 cccatgcgaa ttcattttat aagactaatt tgagtgtttt attaactgaa ttggactgtc
     7501 attcgatcga attatgtggg gcacaagcag agtattgtat agatacgact gtgaagtttg
     7561 ctcatggatt aggataccag cttatgatgt gtagaggagc aacgacaact tatgataatc
     7621 cttttatgaa agcaaaggaa acaatcgctt tttacgagaa aatttgggat aaacgatttc
     7681 tgacattttt ggagcaataa gttgtttctt cgtttaaaaa aagcagaatg gatactggtt
     7741 tatccattct gctttattac gtaaaatgag aaaataatcc tgttctattt ttatgggata
     7801 aaccatttat tttttgtata aaaaatgttt gcgtttacat ataattctcc tagaaacata
     7861 aaaaggagtg aatagcttga gaacaaaaca agtattaaag ggagcgttgg tcatcttatt
     7921 tgctgtaagt acaagcgtcc cgcaatggac agtatatgga gagagcattt cttccgaatc
     7981 ggaatctcgg gaggtagaaa ccacagaaac tactgatgct ggaaatgaaa cgaaatcgag
     8041 tacttcacaa acagaaacaa atactgaaac aacggttgag acatctgtta ctagcacaga
     8101 tcaagaaacg accgctacca cagataacca acaaacagaa gaagcaacag ctacaaaaat
     8161 gtcaaacgac gaatcctctt ctgctaaagt aagtgacaaa gagaatggga cagaaaatga
     8221 tgatatcggt aaaggtgaaa atttcaatgg taaagaatat ttgaattact tcggtaaaca
     8281 gatgacagaa atacttaatg gaccaacaga agacatcaag tcaaaattaa tagagttatt
     8341 agtcactgag cttgctgtta atgattatgg tgtagataaa gagattatca aacatctgat
     8401 tgctacttat ctattgtacg atatcgcttt tgcaaaaaac agtgtgttga tgtcgatgct
     8461 tggaggtaca gatgatggga caacgcctac agaaaacaca ggcttctatc caaatacaaa
     8521 acaacttcat caaactgtac taaacaaaca agatggcaaa atgatggatg tatatgcata
     8581 ttatgtcgat caaggttcag ataaaacagt catgatccat ggcggatttc gagggaattg
     8641 gaataacggg atcgttacag aagaatacaa tgatttttat aaggccgggt ataatttatt
     8701 atttgttgat tccagagcga ctggtaatag cggaggcgat tatgtgacct atggacaata
     8761 tgagtcagat gacgtccttt actggataaa tcaagaagtt cgagagcggc catctcaaaa
     8821 gattttactt tatggtggtt cgatgggagc agctacgatg atgtctgtat tagcgaaaga
     8881 tattcctgtc aatgtcaaag gaattattga aaattgcgga tttgcatcaa ttgatgaaca
     8941 actacgtttt acgtacagcc agacagtagc ccccgcacta ccggatgcca taaaaaatca
     9001 gttagacatc attggggatc aagagcatga agatttattt atgggccttt tgaaacaata
     9061 ctattttgat caggagatgc atttggatac aaaagctgct ctacctacga ttggaatgtc
     9121 agattcattg cctaaattga ttatccatgg aacagcagat gatgtagtac ctgtgtctaa
     9181 cgcgcaaaaa ttatatgagt tatcaggagg gtataaagat cttttattag tagaaggagc
     9241 agggcatgga aaggcacagg aagttgacca tgctgcctac acgaaacatg taacggactt
     9301 tttgaaagta gtgttccatg atcagataaa cgtaaagtat gtggatgaaa acaataaaag
     9361 tctactcaaa gaccaggacg aaatccagct ttacggagct tatggagaaa attatatgac
     9421 agagcaaaag acattcgaag gatacgaatt agcaaatgtt gaaggaccga ctgaagggat
     9481 ttttaatgag acgataccaa ctattatttt ctattacaaa aaaatcccag tagctccacc
     9541 aaaaaagcaa gatccgacag agaatgcaga caataaggga aagaatgaac ctcgagagga
     9601 tcaatcaagt gatgatacgc aaccgattca gatgacagtg aaagtacaaa aaaagacaga
     9661 tgcaaaaaaa gaatgttgcc gaaaactgga gaaaagaaac attcgcttct catttattca
     9721 ggtggatttt tatctgttag cacgattatc acatggattt ggcgaagaaa gagagggtaa
     9781 atgaatgaaa tggttcaagc gaatagtgat tgcagtacca gttatcatcg tagttatttt
     9841 agtcactgta tttttgatta atcaaatcac accaaagccg attagcttgc ttgttagaaa
     9901 acaatttgac acaagtgaaa aagaacaagt atatgcccga ccagatgatt tccagcaaaa
     9961 aatcgaacaa atcgatataa aaaaagaaat atcctatcct tcaaagtaca aaaataataa
    10021 tatggatatc tacacaccga aagtggaaaa gaaaaaatta ccgattcttt tctggatgca
    10081 tggaggcgca tatgtaggag gggataaaaa tgattgtcgt gattatttgg aatatctatg
    10141 ttcagacacg cagcaaatca tcgtaaatat agattatgaa cgatcaccgg aagcaaaaca
    10201 tcctacacca gttatccaat tgaacgaagc cattcaagca gctaaaaaag agataaaaga
    10261 tcaagcagat tggtcgaata tttcgattgg tggaaattcg gcaggtgcac aaattagtgg
    10321 agaatatttg ttagcacttc aaaatgaaga aattaaaaaa gctgatcatc ttgatccgac
    10381 tttggagaac aagcagatta cgaagtttat ttctttgtct ggtctgttgg atccttctgc
    10441 acttactcaa gtaagtgata aaatctctag ctttctttat gaaaaatgtg gatgggctta
    10501 ctttgataat aaggactttg aacaatcaga gaaggtcaaa agtttagcct tggtcagaca
    10561 tgcggatcgt tggacgcaaa acacattctt aacggatgga aatacaaata cgtttacgaa
    10621 acaaatggaa gaagtaactt ctgtatttga gaaagcgggg gtgaaagtca caaaagtaga
    10681 ttatgcggag aaaaatgctg ttttgaacca tgaatatcag tttgatttca gcaataaaca
    10741 agcgcaagaa acatatcaaa agttagtaat gtttttcaag gagtaaagtc ttatgatgca
    10801 aaagaggttg taatctgtca cttagctcca agtcacaagg agcaatttca ataaacaagc
    10861 ttttcatggt ttatgaatat tgtaacttgt gactgaggag ttagagatgg caaggggcac
    10921 cttttattcg aaatttggga atatcacacg attattgtca cgatctcttt tacgtaaatt
    10981 ttataagtca gatttgttgt tttgatcgtt taaaaaaagc aacaaatccg aagcctgcgg
    11041 aggcaagaag ggacaaaaag ccgagtggta agcaaaagaa tgctggttcc actaatattc
    11101 cgttgttatt gatataaggc tgggaacaaa gatgaatagc aaataaaatc aatgcactag
    11161 cgaaaaaaag caaagaaata tggatagctt tcataagcag cacctccttt tttataattg
    11221 tatgataaat agattaagaa tctataaatg tgacaagttt gttaggatgt gaataaaatg
    11281 atcatctagc gaacttgaaa caaagatggc taatgataag caattaatga ttcagcaatc
    11341 agataggtac aaagtttacc atcatacgtc tagaccaata atagaaaata tgggaatata
    11401 atagaaaaga tttaggatac ccccaaaaga atttccccaa aaattcgatg tatcctaaac
    11461 ttttttattt tacataacaa tcatatcaac tgtgaaataa aattacaaat gataacctaa
    11521 aatgaggcca aaagccagtg ttatcaagga aatacttaat tcaccaaaat tttttttaat
    11581 tttttagaaa ataagaaaca aaaataataa aaaaaagaaa agataaattt tttactactg
    11641 tatactaact ttgttatcgc atctaacaag taactcgaat aataccaata caaccttctc
    11701 caaagatgcg atgacatacg ttctaaccca ccgactattg atgttctgta ccacccttgc
    11761 agaaccaaaa aagccactac caaatatttg gtagtggctt tttttgtttt atggattttt
    11821 cgctttttct gttatggtgc tattctttga tttcagaaat agtatgtcga actttagcga
    11881 tagaacgacg tgattctttt tcgttgtaaa acatcaaaat cacatataga gagtccaaaa
    11941 tgcttagttg agaaatacgg gaagctaaag cttcagatcg gaattctgtt tcttcagaaa
    12001 tagaaataaa aacgacatcg ccaagtttag caagggaaga attagcttgg ctagtaataa
    12061 cgattgtttt tgctccagtt tttcttacgg tttcagcaat atggattgtt tcttttgatt
    12121 gccctgtgtg agaaatcaaa acagcacagt ctttttccgt caataaagaa gcttccatca
    12181 attgaatatg gtaatccgtg ctgtgagaag ttgcgatagg ggaacgcaaa aatttatgat
    12241 aagcgtcagt tgctacaatc tctgaaccgc caacaccgaa aaaatagaca cgtttagatt
    12301 cattgataat agtagccgct ttttttagat ccttttgttg taacaacttt tttgtgtcat
    12361 ttaaagttga aatactagac tcgaacacct tttgcgccat agtgagctca gtatctgttt
    12421 tctgaatatt ttcgtggata gaaatagcag atagatcatt ttcttggatc aacatggcca
    12481 ttttaaaatc tttaaatcca ttataaccaa gtttttttgt aaattgaaaa aaagtagagt
    12541 cagcaatgcc cagttcactt gctaaattgc taataggact atgacttact ttgcttggat
    12601 tttctaaaat ataatcggcg atagcctgtt cttttgggct gaagtcgttg tacattgttt
    12661 tgatttgtag tcttatggag acgctcatga gaattcctca ttttcataat aagattatca
    12721 ttttttccgt tctcattaat gttaaagata caaggagagt aggaaaaaat caaacaaaaa
    12781 atatttttgt aaaatctatt tacaaaaaaa tttttttgta taatgagggt ataagaaatg
    12841 gaggcgctat catggaaatt ggtgtaattg gtttgggaaa aatgggattg aatttagctt
    12901 taaacttaaa agagcaccat cacaaagtac aaggactcga catttcaagt acagctgtta
    12961 gtcaggcaag agaaaatgac attcctgctt atcaagagat ctctgaattt ctagctactt
    13021 ttgagcagaa aaaaatcatc tggttaatgc ttcctgctgg agagataacc gaaaacatgt
    13081 taagaaaact ttttccaaaa ctcggaccag gagacattat tattgaaggc ggaaactctt
    13141 attataaaga ttcaatccgt cgagcagaag agtttcagaa aaatgaaatc ggttacttgg
    13201 attgtgggac ttctggagga atcgaaggag cacgacatca agcctgctta atgattggag
    13261 gagataaaga aacttttcta tccgtggaac aattattcaa agatgtagca attgaaagag
    13321 gatatctgta tgctggtgca tccggaagcg gacacttctt gaaaatgatc cataatggaa
    13381 tcgaatatgg aatgatgcaa gcaatcggtg aaggattcca acttgtacaa aaaagtgagt
    13441 atgcttttga cttggaacaa gtcgcacgtg tttggaatca tggttcggtg attcgcggct
    13501 ggctgatgga aatcatggaa gatcagttaa acgaacatcc caatttaagt aattatcggg
    13561 gaatcgtttc tgcatcaggt gaagcaaaat ggacggttga aacagcgcta gaaatggctg
    13621 ttccagttcc agtaattgca actagtttgt tcatgaggaa tctttcacag gaagaagata
    13681 gtttttcagc aaaagtagtt tcagcactaa gaaatgggtt tggcggacat gaaatagttg
    13741 aaaagggtga gtaaaatgcc agattatcat atagcaatcg ttaattccag cagtttcgga
    13801 agagtctttc cacaccactt ggaaagatta aagtcagttg gagacgttca tttctttact
    13861 gttgatcaag agattccagg aaaagaacta gcggagttac ttaaaggatt caatatcatt
    13921 attgcaagtg ttacgccatt ttttcgacga gatttttttg aaaacaaaga tgaactgcta
    13981 ttgatttccc gacatggtat tggttacaac aatattgatt taaaagcagc aaaagaacac
    14041 cagacaatcg tatctatcat acctgcttta gttgaacgaa atgctgtagc agaaaataat
    14101 ataactaatt tgttgtccat gcttcgacgc acgacacaag cacaagcaag agtcaaggac
    14161 gatcgatggg aagatcgggc ggagttcgtc ggtaggacgc tgtttaacaa aacagttggt
    14221 gtgattggtg caggaaatac cggaagcgga gtaatcgaaa ttttgcgtaa cggttttcgc
    14281 tgtgatgttc tagcttatga tccttacaaa tcagatttat acatcgaaag ctttggtgca
    14341 aaaaaagtag aacttcaaga attactggaa caatcagata tcatttgttt atgtgcgaat
    14401 ttgacagaag agaactatca catgatttct gataaagaag tcgatcagat gaaagaaaat
    14461 gtttatctat ctaatagtgc aagaggcgct ctagttgatg aagaagcgat gattaatggt
    14521 ctgaaaagcg gaaagatcgc aggatatgcc acagatgttt tagaagaaga accgggacgt
    14581 caagatcatc cgtatttagc gtttgaacaa gtagtgatta cgccacatat atcggcctac
    14641 acaagggaat gtttagaagc aatgggtgaa aaatgtgtca gagatgtcga acagatcagt
    14701 cagcaccttc ttcctgaacg ttctgtccag acaaagagca actatataaa aggatgatga
    14761 agaaaatggt gaacggttta aaagtgaaaa caggccctca attttattta tatgaagaag
    14821 gtggtatttc aaaagtttct gatctcttga aatcatacgg cgcgaaaaga gtactggtca
    14881 cccacggaac ggtatcatgg gaaaaggcgc tacctaaatt agtatttttg aatgacgaaa
    14941 cgattcaatt tttttatcat cgttattctg gagaatgtag ttatgctgaa gccagacgaa
    15001 tagctacaat catcaaaaaa atgaaatcga tttcgtagtt ggcgttggcg gaggaaaact
    15061 gaccgatcta gtgggttata gtgccaatct tgcaagaatc gatttcggag tcatccctac
    15121 tttagctagt aattgtgctc catggacacc tcttgctgtc atgtataagg agaatggaca
    15181 agcagaaggg aaaacagaac acttttacag acaagctgct ttttttataa cagatcccca
    15241 attagtgatt gattcccctg ttccatattt cattgccggg ttagcagata cactagcaaa
    15301 atggtatgaa tctgagctca tcttagaaca agattttttg caagatgaat catttttgaa
    15361 gctagcacaa gatactgcga agatctgcaa agaagagatt ttgaatcatt ctgctaaagc
    15421 aatccaagat atggcacaaa gaaaactgac atcggagttc aaacagcttt cagagattat
    15481 ctttgctgtt gctggtttag ttggaggatt aggagataaa tacgcaagaa atgcggcagc
    15541 acatgctatg catgacgcta tcagtaaata tattccggaa agccatcgtt ttctacatgg
    15601 agaaaaagta gcgtatggga ttttctatca actggcacta gaaggtcgct gggaaaaaat
    15661 agacgagtta tatcctttgt atcgggaatt agaactgccg gtttctctag aacaaatggg
    15721 attatttccg aaagataaac agataataga taaaatggct gaatttattg attcgaaaga
    15781 gaaagtgcat ttgattccta tagaggtaac acagaaatca ctgatacagt caatgatgga
    15841 actggaaggt tatatcagaa agatctgaag gaggaggaca catggaaaca ttaagtgtag
    15901 tacaaagttt gttgattgct ttatgggtag ccgcggttat gtcccgctgg ttaggtggag
    15961 gagccacgtt gaccttacgt ttttctcctt tgatgactgg attagtcgtc gggttgatca
    16021 tgggggaagt tgcacaagcg atgattgtta cagccgcttt gcaaatgatt tatatggggg
    16081 ttttttctcc aggaggatca atgccagctg aaccatctat tgcagcagct atcgcagtac
    16141 cagtcgcatt attaggggat ctgtcgccag aagcagcgat tgccgttgcg gtgccagtcg
    16201 gattgctcgg aagttacttg tatcagtttc gttttttcat caatactttt ttaggtaaat
    16261 atacagacaa agctgtagaa gatttgaata caaaagctat ggcccgatca attattcttt
    16321 atccaacggt tgcctcattt ttattattcg ttccgcttgt tttcattgct ttatatttag
    16381 gggcgccatt gatcgctgat gtaatcaaag ctttagaggg aacagtcgtt atccacattc
    16441 ttgaagtagt aggtggaggg ttagcggcaa tcggtatcgc gacaactgta tacgttatcg
    16501 gtcgaaaaga ttatctggtc tttttcttcc ttgcttattt tatgagtgtt gttttgaaat
    16561 ctttagatat tacgatggtt acttatgcca tttttgggat tattatcgct ttgatctttg
    16621 tccagtcgca aaaagggaaa caagtacagc ctgccacaag caataacaat tcagcatctt
    16681 ttgatgacga agatgactat gatgacggat tttaatttag gaggaatggg aaatggctga
    16741 aataatggat aatcaaacag gtgctcctga agaaatcacg aaaaaagatg taacaaaagc
    16801 ctatctgaga tggcattttg caaacgaaat tcctcactct tttgaacgtt acttggcgcc
    16861 atcactacta tacggaatga tgccaatctt gaaaaaactt tataaagatg aagactcttt
    16921 aaaagcagca tataaacggc agttactgtt cttcaacact caattaagct ggggtggcgg
    16981 tgtgattact ggcctaatgt cttctatgga acagcaaaga gcagaagaag agtatgaaga
    17041 aaaagagatc ttgatgcagg atgacttgat gtataacacg aaagcgggat tgatgggggc
    17101 actagcagga atcggagatg caatcgattc aggaaccgtc caatatattt ttatcgcaat
    17161 cgcggtacct tgggcacaac agggaagtcc tttaggcgca ctttttcctt ttatctgctt
    17221 tgggttgtat caggttttac taggggtatt tttcgcaaga caagctttca ctatgggccg
    17281 taatgctaca ggcctaatgc aaaacactgg tgttcagaca gcgattgaaa tgctatcagt
    17341 tttagggttg tttatgatgg gggtgcttgc gggaaactat gtaaaagtag aatcttcatt
    17401 gaaatttgcg atatccggac gtgagtttgt tatccaggaa attcttgatc aaatcgtgcc
    17461 agggatatta cctttagctg tcgtaatggg tgtgtacttg ttctatacga aaaaaggatt
    17521 gaaagtcaca caagcattat tatggctgac tggaatatta attgtgctag caggaatcgg
    17581 tattttataa aaagaaggga acgtgaataa gatgggtgta gtcaatttag cgcgtgtgga
    17641 tgagcgtttg atccatgggc aagtaatggt aacgttatct caaaaaagtg gagtgaattc
    17701 catttttgtt gtagacgaag ttgtagcaaa agataaattt atgagagatc tttacaaaaa
    17761 tgcaggaagc cgtacaggac aaaaaacaat tgtcattaca ccagagaaag ctaaattcta
    17821 ttgggatgaa tatcaattta aagaatacaa ttgtattttg atcgcaaaaa cagtccaaac
    17881 gatttacgac ttagtaaaac acggaatccc catggaagaa ttgaatattg gagggattgc
    17941 tcaaaaaaat cctgatacag atcttttagt gacgaaatct gtttatttaa ataaatcaga
    18001 tgctgaaaaa ttgaaagaaa tgaatgaaca atatggcgta aagaatattt attttcaagc
    18061 cactccatct gcacctaaaa caggattaaa agatgtattg aacaagtttg atttgtcata
    18121 aacaaatgct tagaaaaaag ataaagaggg cgaaaaaatg aagaagaacg agctgtttcg
    18181 tgattgggaa tttcgttatc gctatattta ccgtaagcgc cgtacaaaaa agagtaaaca
    18241 gcgttttctt tcagcattag tatcagatat ttacagtatg agaacagatg tgacagtcat
    18301 tgcttacgat acgctagcct accgatcaaa aaatatttat gttggagata tcgaaaaagc
    18361 agagaaagtt atctgtactt attacgatac acccgttcat gcattaggaa gttatttcat
    18421 gtttgattgg aaagaccaaa ggaaaaaaac aatctactct atattattgt ccttcatttt
    18481 gttgttcagt ttaggttggt ggggaatgat gatatataac aaaaatcctc atcacgtatt
    18541 cgatctgcta tccgtataaa caggtatcac tgtactagca tttgggagct actttttctt
    18601 attgggaaaa gcagctcgcg gatggcctag cagacaaact tttattcgaa atacttcatc
    18661 catattaacg atgctagaaa tgatccgtac gattgatgat ccgagtgtag cgtatgcgtt
    18721 tgttgatgaa ggctgttatg gagaaaaggg cttagacagc gtgagatcgg gtatgaaaaa
    18781 agaggctatt cttttttatc tagactctgt tggggcagat acaccgctac agttttcggg
    18841 aaattatttt tcaaataaag aacagtggct gaaacaagtt gataagttga aagaaaaaaa
    18901 cgtcaattat atttttagtg caagaaaaaa gcaagcgcag ttcttctatt tgaccaaaac
    18961 agatttacga gggaaaacat ttaattggca aaatgccaat cagattattg ctctttttcg
    19021 ataagtaaaa agtgcaaaac aaggagtgag aagactaatg ttggaaatca tgatcgttac
    19081 acatggtaag ttgagcgaag gactgaaaga tgcggcggaa gtaattgtcg ggacatcgag
    19141 ccatattgaa acaatgtgct tagagtctgg ggaggacatc caaacattcg gagagaaggt
    19201 caaagaaaaa ttaactatga tcaacacagc agaacccatg ctagtatttg ttgatctaat
    19261 tagcgcaagt ccgtacaatc aagcgctctt ggcagtcaat gaactgactg aagaaaagaa
    19321 agcagccact tatgtcatag ggggcgtgaa tctgccaatg ttgttagaag caatcaatca
    19381 tcagatgctt cacacaccga tagaagaagc ggtggaacaa attgtcaaac aaggaaaaga
    19441 taatttaact gtttggcatg cttcagcgga agaaaaaaaa ttagatgagg acgattttta
    19501 gaaggaaggc tgaaaagatg aagtggggat ttagatggta tggtgaaaaa ggggattcga
    19561 tcccattaaa atatgttcgc caaataccgg gaataaatgg gataattgga actttgctga
    19621 ctaaaatgcc tggagatgtt tgggagattt cagaaattga ggagttgaaa gcatctgttg
    19681 agagccaagg actggaactg cttggaattg aaagtgtagc gatccacgat gcaatcaagg
    19741 cagggacaga tgaacgagat tactatattg ataactatat acgaacaatc aaaaacttgt
    19801 ctcgatgtgg ggttcgattg atttgttata gcttcaaacc aatttttgga tgggcgaaaa
    19861 ctgatttgtt taatgaaaac aacgatggaa gctattctct tttatacgat cagaaaatcg
    19921 tcgatcagat ggagccagga gaaatgtatc aattgataca cagccagtca aagggattca
    19981 aattgccggg ttgggaagaa gaacggttga aaaaattcgc tcagctggaa aaactgtatg
    20041 aaggaatgac cgaagaagaa ttatttgaaa atctgactta ttttttagaa aaagtgattc
    20101 cagtgtgcga aaaagcagat gtaaaaatgg ctatccatcc agatgatccg ccatgggaac
    20161 tttttggttt tcctagagtg acgaaaaatc ttggcgactt gaagaaaatt ctaaatgcag
    20221 tagattctcc atataatgga ctaacgctgt gcacaggatc tttaggggca aatccggaaa
    20281 acgatttagt tgaaatcatc catgaggtag gttcgcgcat ccattttgtc cacttcagaa
    20341 acgtggagtt tttaggagaa agaaagttca aagaaacggc acatccctct acagaaggct
    20401 cccttgatat gtatcatatt atgaaagcgt tggtgcaaga agggttcgac ggtcctatac
    20461 gccctgatca tggtagaacc gtgtggggtg aagtggctat gcctggatat ggcctgtatg
    20521 atcgtgcaat gggactcact tacatgcaag gtctatatga ggcgataagt aaggaaaaac
    20581 cactgggaga gcattatgaa taaaatcaag ctcttcatct ttgatatgga tggcctttta
    20641 ttagaaactg gacgtttagc ttatcgtgct tatgtaaaat cagcacaaaa gtatgattat
    20701 gaaatgcgta aggaagtcta ttatttacta actggccaaa cagaaatggc gataagagaa
    20761 caaatgggca ttttgtacgg agaagatgtt ccatatatca aatggcgaga agcaatcaat
    20821 caatataaag aaaaaatcgt gaaagaagat aagagagtat atacgaaaaa aggagcagaa
    20881 gaaattttat cttttgcaaa agaaagagga atccatacaa tcgtggcttc gtctaataca
    20941 cgggtaaaag tagaaatgta tttaaaaatg gaaaatctat atgccttgtt tgatcaaatc
    21001 atttcagggg atgatgtaaa aaaaggaaag ccggaaccag agatcttttt gaaagcttgt
    21061 tcaaaaatga atattcctcc aagtgaagca cttgtatttg aagactcgat tgcagggatc
    21121 gaagcagcaa ggcgagcggg cattttgtct tttctcatca aagatcattt gatagggttg
    21181 cccgatcata atgggaagca taagttgaaa gtagatgtaa gtttatatga atccaataaa
    21241 gcagactatg aattttatga cctgcatcaa gcaaaacgat ttttagaaag taaagggttg
    21301 tatctctaat aaagaggact attttctagt cctctttatt tattgtcctg cacgactgag
    21361 ggaacagatg aaaaagaagt aattttttat tttgaagtat ctaccttatt tgtagtgaac
    21421 aatttagaac aaacacaaaa cgcatctact gttatctacc agtagatgcg tttaaagaga
    21481 agaacgagaa tcgtccatat gagggtttcc actccttatg cagatttttt taattcttgc
    21541 actgcttgtt cgatcgtaac acctgtcgct acatgattgg tattttcttt gtcaaaaacg
    21601 acaaatagat tcaaatctgt atccaaggtt actcgatatt gtatatcttt gttatagaat
    21661 gtcatagcca ttctcctttc tttaaatact tgctgaaagg caacgaacgc gttgataacg
    21721 aaattccatt tataagtata ccaccaattg aaaggttttc atagttaaga aattttaaag
    21781 tcaaaagttg cagataaaag caaataaaca agaaaacaaa aagtgaatca atcgcggtta
    21841 ttcaactttt tcttcgattc gaagacaata gaagacaatg aattttatat ttcattgcat
    21901 tatccttgtg ttattagaaa aagcatgata tattaaatga gtaatctatt ttgaaacgta
    21961 atttgagcga tatatctaca tagataaaac tccttttgcc tatcaaatat ttattgcaac
    22021 gaaaaaacgt acattgatac gtatcaggag gaatttattt atgaataacg gtacagtaaa
    22081 atggttcaac gcagacaaag gttttggctt tatcactggt gaagatggaa atgatgtatt
    22141 tgcacatttt tcagctatcc aaggtgacgg cttcaaaact ttagaagaag gccaagcagt
    22201 gtcttacgat gttgaagatg gtcaacgtgg ccctcaagca acaaacattg ttaaagctta
    22261 ataaaaattg acttttaacc gtcttttcga aagaaaagac ggtttttttg tacgaaaaaa
    22321 ttc
//
LOCUS       DACDAF010000046        21616 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.046, whole genome shotgun sequence.
ACCESSION   DACDAF010000046 DACDAF010000000
VERSION     DACDAF010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.046"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..504)
                     /locus_tag="IVZ69_001614"
     CDS             complement(<1..504)
                     /locus_tag="IVZ69_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183699.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQ"
     gene            complement(728..1612)
                     /locus_tag="IVZ69_001615"
     CDS             complement(728..1612)
                     /locus_tag="IVZ69_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HAP8183700.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(1711..2148)
                     /locus_tag="IVZ69_001616"
     CDS             complement(1711..2148)
                     /locus_tag="IVZ69_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183701.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            complement(2365..3276)
                     /locus_tag="IVZ69_001617"
     CDS             complement(2365..3276)
                     /locus_tag="IVZ69_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP8183702.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(3733..4161)
                     /locus_tag="IVZ69_001618"
     CDS             complement(3733..4161)
                     /locus_tag="IVZ69_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183703.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     AKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            complement(4189..4827)
                     /locus_tag="IVZ69_001619"
     CDS             complement(4189..4827)
                     /locus_tag="IVZ69_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183704.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(4831..6867)
                     /locus_tag="IVZ69_001620"
     CDS             complement(4831..6867)
                     /locus_tag="IVZ69_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HAP8183705.1"
                     /translation="MIIKKKFTVLLTIIVTGIMSGFALVSINKQVLYRTNEFFHQTDT
                     YTPIRLPQHFIGQEEYEQLIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLE
                     MTLYYQGDVKSSHEKVPYSNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERVISLF
                     TDRFNQAFHTDYATNIFEDFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLL
                     MNKEISLLLNNDFSLHQVLWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYV
                     FLFSGIYGISLISLLLVEKIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFS
                     SSQLAVSHEPPKEIAGEDYHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSI
                     LVNVSDYLNEENEQFGRGIKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRH
                     TDLKNDLAQITEYYQEISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSM
                     YLERNILSGEIYPPLKIKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLS
                     RSFHYLIQIFLLTFFSFFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNL
                     IKWGTTSVIFLFLIEREPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            6993..7658
                     /locus_tag="IVZ69_001621"
     CDS             6993..7658
                     /locus_tag="IVZ69_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8183706.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDF
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            complement(9593..12742)
                     /locus_tag="IVZ69_001622"
     CDS             complement(9593..12742)
                     /locus_tag="IVZ69_001622"
                     /EC_number="3.1.21.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="HAP8183707.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDSQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDGVYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNEKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKTLMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSSEQINRMIDQMEPVKKESYLDPAVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQLIREGRTM
                     EDPDFPRIAITYSLEENSRDSSAQQEEMQKIIEEYNQYYDTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLAIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PDKTKGLIVTFRKPATMEKNVEDATKLYSKAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSPTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYLPGEDPIPNMKAIINSKDYEGYKAKHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(12755..13954)
                     /locus_tag="IVZ69_001623"
     CDS             complement(12755..13954)
                     /locus_tag="IVZ69_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HAP8183708.1"
                     /translation="MSNDTRPEIRFPGFTEDWEERKLIDLVVRLNKSTNSSRLPKVEF
                     EDIVAGEGRLNKDVSQKFDNRKGIEFLPNDILYGKLRPYLKNWLKATFTGVAIGDFWV
                     FRAKKSDSDFIYSLIQADRYQKAANDTSGTKMPRSDWKKVSDTVFYIPNDLKEQQKIG
                     IFFKKLDDTIALHQRKLDLLKETKKGFLQKMFPENGAKVPEIRFPGFTEDWEERKLGE
                     LGKTQSGIGFPDAEQGGSEGTPFFKVSDMNNIGNEYEMRNANHYVSNEQIERKKWKPI
                     KDVPAIIFAKVGAAIMLNRKRLVTSPFLIDNNTMAYLFNNTWDIYFGKILFETINLPR
                     YSQVGALPSYNSSDIENISVKVPVKDEQQKIGTFFKQLDDTIALHQRKLDLLKETKKS
                     FLQKMFV"
     gene            complement(13944..15539)
                     /locus_tag="IVZ69_001624"
     CDS             complement(13944..15539)
                     /locus_tag="IVZ69_001624"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HAP8183709.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAIAPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVDVLEHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLATFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEMWLQGALEVFKHEQ"
     gene            complement(16123..16830)
                     /locus_tag="IVZ69_001625"
     CDS             complement(16123..16830)
                     /locus_tag="IVZ69_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183710.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENG"
     gene            complement(16895..17731)
                     /locus_tag="IVZ69_001626"
     CDS             complement(16895..17731)
                     /locus_tag="IVZ69_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8183711.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(17749..19158)
                     /locus_tag="IVZ69_001627"
     CDS             complement(17749..19158)
                     /locus_tag="IVZ69_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP8183712.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(19172..20995)
                     /locus_tag="IVZ69_001628"
     CDS             complement(19172..20995)
                     /locus_tag="IVZ69_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8183713.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(21275..21502)
                     /locus_tag="IVZ69_001629"
     CDS             complement(21275..21502)
                     /locus_tag="IVZ69_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183714.1"
                     /translation="MIEIGYCLLIFTKKTSITIVAYIVGMLFIPSFTHQIHQFFPRAE
                     LLKLCDPLYAFLMLSRFWEFPAGYVGMVLLV"
BASE COUNT         6551 a         4353 c         3421 g         7291 t
ORIGIN      
        1 ctggaactcg atcgactgag gtatctcatt gatataaata tggtgtgtgc cgaaattgtg
       61 agcgaatcca ccaaaatcaa taacgatatc tcgtttgatc tctaattccc tgtctaaagt
      121 caaaggctga atcagtcgga tcttagttac tgattcgtct gcgagaagct gcgccagttc
      181 ttctgttgtg gcagcttcgc tgtacccatc cgctgaaaca gctcttgcca gtgccgcttc
      241 actgctatca gacgtttgtt cagctacttc tgaggtctca cttgtcttat tttcttcttg
      301 ccttttatta gtagaagcct cactttgaga ttctgtagtt tcagaagtaa tcgattcttc
      361 tgaaaaagta gtcttgtcaa aactttgatt ctctgattgc gttgattcgt ttgttttctc
      421 tacatcggca aaaacggatg tcaccatcaa gagagggaag acaaacaaaa tcgacgcaat
      481 cagctttttt acacattgat tcattctcca ccatcctctc tgacgttttg acaattttat
      541 tttatcgttt taatctattt ccaattgtac tttcatattt aaaatatgta tttttatgga
      601 aaaatttttc tattaggtgt aaatttcttt tttgtacaaa aaaaaggctg tgacaaaagt
      661 cttgtcacag tcccttatcc cgaacaagcg gtgttctccc gccaactcct cggtcacaac
      721 ctccatttta acaataaacc tgtaaatgtg agggcaatac tttgattgtc acaggtaatt
      781 tatccccttc atctccatca acattcgtcg tcaattcttc ctcatcagct aatgacacaa
      841 ctaattgctc acaagtaagg taggctagat ttttcgtaga ttcatctact ccttttaata
      901 ggtctggcaa tgttttaagc gtatcgatca aagaagaatc ttttaaataa accaaatgga
      961 gcttaccatc atccactttt gcatttggaa gtaatgtttc aaaaccgccg actgagttag
     1021 ttagtcctat cagcaaggta ctgctctcaa tttcttcctt ctttccatca acttctacgt
     1081 gaaacgagta ggattgtgtg gaagctaact gtttgattcc tgacatgaaa taagctagtt
     1141 ttccaaattt cgtcttcttc tccgcatcta catcattgat tgattcaggg atagagccaa
     1201 ttgcgacgac attcataaaa tagtcgtcat ttatttttcc aatatccaat ggcttgactg
     1261 attcaatcga aaaatgattg atcgcttcct caggttctag cggtatccct aatgctcgag
     1321 ccaagtcatt caccgtaccc aatgggaaaa atccgaaatt tggccgatgt tcttgttcag
     1381 cgattccact gattccttcg ttgactgttc catctccgcc catgacaaac acactatgat
     1441 acccttccgt agccgcttcg cgagtaaagt tttttgcatc ccctgctttt tttgtatgca
     1501 agacgaccac ttcatcaaac accgattcca attttgctat cgctaattgc tcaaattcct
     1561 ttgcttgttc accgcctgaa ctggggttta ccactaataa aacttttttc atcactttct
     1621 ttcccttctg actgattgat ttctttaata taacgatagc ataaagaaaa aaattaggct
     1681 gtgatgaagt actgttcatg aaacattcat ttattttttg acaagataaa acatccatac
     1741 tatgaaactg aggaaaatta aaacaatgat ataggaaata aaagaaaatg ataggcattg
     1801 tatacctaat aaagtaaaaa tcttaggtgg cagataaaaa cacaaaaata gcaagagaat
     1861 gtaatagcgt ttcttccact ttttgttatc agaccttata gcgatcagag gaataccaaa
     1921 tgcataactg aaaaactctt gatgtactgt taatatgtca cggccttgaa taataaatgc
     1981 gacaatcccc gctataatta gtgtgcctaa caccaaaacg gaaaattgat gaatatattt
     2041 tatatacaaa tgatccattg tacttcctgc ctttttattt gtgagaaaaa caaatccgta
     2101 tacgtgaata acttctagaa ataaaagaaa tttgcaaaac cactccattt atctacttct
     2161 acgtgcattt tttgatattg ttttctttat ttaagattat acagaaaaat atctagggtc
     2221 gctggattct aagtaaaaaa aatttttaaa ataaaaagaa ctaaatcaag tagtaattaa
     2281 actactgttg atttagttct aataaaaaga tttagatgaa cagttttatt gatttaaata
     2341 gttcatattt tttatttata ccgcttattt actacttgct gtactagaat ctgaagtgaa
     2401 tgtactcaaa acattttcaa agtctttgtc tttgattttt acattagcgt ctttcaatac
     2461 ttcgccaatt actttattct ggaaggtact gtcacttaat tttgtgtctg ttgcaatttc
     2521 tttcaattct tttttgtatt tatccatgtc gttgcctttg ttttggtttt tcaccatttt
     2581 aaccacataa tattccgtag tataagttga agcattggta gaagtgatca catcagaaac
     2641 ttgaccatct ttcaacttaa aggctgcttc tttgacttct gccggaaccg ttgtagtagt
     2701 ggaatcaaat ttcacttttc cgccatcttc ttttgtcgta gtatcagttg acttgtcttt
     2761 ggctaattta gagaaatcgt ctcccttatc agcagctttc ttcacatctt ttgcatcatc
     2821 ttcacttgct acttggataa tttgagcttc cacttctgga tggaaagatt cccaagccgt
     2881 ttttaaatct tcatcggtca atttgatatg tttctttaga ccttcttgaa aggctagact
     2941 ttgtttgata ctgtctttga atgtttgttc tgtgtaacct gcagatttca attgtgaatc
     3001 aaatgaatca cccaattgtt tctttgtttg atcatattga gaatcgattt ctttggttga
     3061 tacgtcatct ccatatttat cttcaaatac ttgataaacg atcaactgtt gcacagcgga
     3121 atctgctcct tgcatttttt tcaagctatc cattacttct tgttcgctga ttgtaccgcc
     3181 tttataacta acggctgttt tttcaccggc attcgtacag cctgacaata agccagtgcc
     3241 tagtacgatg gcaagtgcta aaaatctttt tttcatttat caattctcct acttttcgtt
     3301 ttttgcgaat tgctaaaaac aaaggtgttc aagatgaaaa tcatcaagaa cacctttact
     3361 aatctgctcg atacgtcctg aatagatata aggctacaca atccagaaag ttcgctcagc
     3421 agaataaatg tcaagtagca catcacacct taatatacta cttcttttgt taccgttttt
     3481 caagtctatc ttgcgttccg tatttaacgt aactaattct tagaacaaat gttatcgatt
     3541 ttgtttttct tcttccgctg ctgggatatt caaatcagac acttttatgt tcgattttcc
     3601 agacattttt ttgttgtttt tattatgata tatttttata caactaaaaa tgaatatatt
     3661 aaaactacca aaaataactt ttaacgctgt ttcattatat gttttttcta ttttatataa
     3721 acttttggat acttaatacc aaccggttgg attgtaccaa catgagaatg tgtcagttct
     3781 atttcctgtc gcacttgcat aggcccatac tccttttgtt gcatttgctg atcgaataga
     3841 gtttccaact ttcgcttttg caccgtgacg attatagaca cgactatagt ggttagaatg
     3901 acctgttttt ctcgtacaag ttgtatcact ataataaacc catcttccag agctatgatt
     3961 aattgctgtt ctagaaattt cccggtctac tggtaaattt gacttaataa tattaccttt
     4021 agcatcaaaa tgaatctctc ctggctttaa agatttgtaa tagatttcac cgtgaactga
     4081 atttgcttcc acttcagatg acatagcgtt tcctccaaca aaacctatcc ctagtgcaca
     4141 aataataact gcttttttca taaaacgaca tcctttcctt tttgattttt aaagcatgat
     4201 cttcttgttt cctattttgg tcagatatgg atcatgcgtg actacgataa ctaacgtacc
     4261 ttgggaagct tgttgcgata agatttcaac tactttatcc ttatttcttt tatccaatga
     4321 cccagtcggt tcatcggcta aaatgatttt gctattcttc aataagactc tcgcacaggc
     4381 gattctttgc ttctcaccac cagataatgt gtagataggc gtacttagct tcttgtttat
     4441 atttactttt ttcaatgcct catactttgc tgttcgctta tctgaaacat ttaaattcga
     4501 aaacttcaat ccaatatcta aattaaaatc gattgtttca tattcaatca acccaaaatc
     4561 ttgaaaaaga aaagatatgg tatttctttt tatcaagcgc ttctctctcc cagttaattg
     4621 tttcgtctct tgatcgaaca aatagaattg tcctgaactg aactgatcat tcaatcctaa
     4681 tatattcaat aacgtacttt tacctgctcc actttctcca acaacagtca caagatcccc
     4741 agcatccgca gtgaaacgat ccaaatgaag aatcgttttg tttcgaatga tttttttcgc
     4801 accttttatc actatcaacg gctccaattg ttaacctcca ttcatcagca ataactgact
     4861 tttcttttct gtagacaaaa taaaaacaac tgaaagaata aaatcaatga agctaaagaa
     4921 aaaaatatta aaaagatatt taggctctct ttctataaga aaaaggaaga ttacacttgt
     4981 cgttccccat ttgatgaggt tcatcatgaa gaaatcttta tacgtttcaa agagcgaata
     5041 accacttgaa cgaaagatag cgattttccg acaattgtag acaaaatata tgcataacat
     5101 gacatagctc aacaagaaga aagaaaagaa agtgagtaaa aatatctgta tcaagtaatg
     5161 aaatgatctg cttaacactt tgacagctat ctcttcagtc tgagtatacg gaaatgataa
     5221 ctgcaagtta tcacgtaact gactttcttc aatcagctca aataaccttt ctttcgacaa
     5281 agagcctatc ttgatcttta acggtggata gatttctccg ctgagaatat ttctttccaa
     5341 atacatactg tttttcaatg tcagtatttc aacaaccgga taatgttcga tccaggggat
     5401 agaaggaata aatgtataaa tgggttgatt gttttttata aatagaaatt tcggttcttt
     5461 ttcactgatt tcttgataat attctgttat ttgcgccagg tcatttttta aatctgtatg
     5521 tctatatcgt tcagggatca atataacagg gtgcgtttct ttttcggtta tttggatcaa
     5581 ccttccagag acatcaatca aaggaaattt cttaagataa ttcagattta tttttatccc
     5641 tctgccaaac tgttcatttt cttcattcaa gtaatctgat acattgacta atatacttcc
     5701 gtttttattc aaagtttcat ataattcctg atctgctgct gatgcaaaac gattggaata
     5761 aataaaatcc acgtggtttt tcccgatggt tactggataa aatacatgat agtcctcacc
     5821 agcgatttct tttggtggtt catgggaaac agctaactgt gaagaagaaa aaacgatagt
     5881 tgctaattcg acattggcaa cggtcaaaag aagagaaaac aacaatccaa atgtaaaaag
     5941 aatgtattgg atatagttga acgcttctct taacgaagcg attttttcaa ctaataaaag
     6001 agaaatcaaa gagataccat atattccgct gaacaagaaa acgtacatct ggaacaaata
     6061 aagaaattgc tccttataat acataaaaat aaaaccacca atgattcctg caattatgaa
     6121 tgtaataatg attttctttt tccccaataa acaccacaat acttgatgta atgaaaagtc
     6181 attattcaac aataaactga tttctttatt catcaataag aaaaaggatg ataacaaaag
     6241 gaataaaaga atcaatccaa tagttaaata cactcgataa ttatatacgt ctgtatttga
     6301 aataaccgaa tacgaatagc tattttcaaa gtcttcaaaa atattagtgg cataatcagt
     6361 gtgaaatgct tgattgaatc gatcagtgaa tagtgaaatg acccgttcat aggcttcttt
     6421 ttctctcgtc atcaagaaaa attcaccttc aaaatctttt attttgatcg attcttcaat
     6481 ggacgttacg cgaaaggagg tattagaata gggtaccttc tcgtgagaag atttgacatc
     6541 cccttgataa tacaatgtca tttcaagctt tggctgtatc ttgaagttcc aagatgtatc
     6601 tacttcattg gattcattta ctgttttttt catataagaa agctcagttt ctgatgagac
     6661 attttcaaat accatgatta gctgctcata ttcttcttgc ccaataaaat gttgtggcaa
     6721 tcgaatcgga gtataagtat ctgtttgatg gaaaaattca tttgtccgat agagtacctg
     6781 tttatttata ctaaccaagg caaaaccact catgataccg gtcactatga ttgtgagtaa
     6841 aactgtgaac ttttttttga ttatcaccac tctcccttac ttaaatgatt ctttgataaa
     6901 atcataccgt ttttcatcaa aaaaacgtat ctatcaagtg tataggtcat gtagaataaa
     6961 tctatatact gtagaatcga aaggagaaga agatgaacac cggagaaaaa atacgaactt
     7021 accgcagaaa ttgtaagctt acgcaaaaag aattaggcga aaaaattggt gtttccgata
     7081 aaacgatttc tagttgggaa aattctcgta caatgccaga ctttgaaatg ctgtcacttt
     7141 tacatcatac tttaggtctg ccgattgatt ttccttctat tgaatcagct accgaatcaa
     7201 tagaaccaac attgccagat gaacctcttg ttaacaagaa atcttattca tcaaaacaac
     7261 ccttctcact caaaaagaca ctatctttct ttctgctcgt cttttgtttg gtctatcttt
     7321 ttcttatcaa ttatcaatac aaaaatgaaa cgatcgatcg attcaatcct tttttgaaac
     7381 cacaaatcgg ctataccaca ctccctgtag gatacgtgga caattccatc gaacgttggg
     7441 tatgtaatga tatctttggc catggtacat ggctgtcttt tcacgctgga gaggtagaaa
     7501 aagagaaaaa ccatgctgta atcaaacaca aaggaaaaca cgtcatgaac gttcgcctgc
     7561 tcacttggga agccattccc tcagattacc aagaaatcct cagccaagac tatgacgacg
     7621 ccttaaaaag aagccctcag gagccagata ggcattaagt aggagatgaa cgtagagata
     7681 gaaaaaatca atgcacatga tcttatccaa aaaacagggg tacaaattaa ttgaaaaagc
     7741 cttgagatga aagttcctaa ataaaaaagt tcagaatgat aggtatttct ggcttatagt
     7801 ataatattta cgccacagcc tcccaatgat tctttttgga atcataatca aggatggaca
     7861 ttcacaaaaa tattttgctc attcgatccg aatagattaa cgaccaatct agtaagtaat
     7921 atagattggt acgtagtcaa gctgcacata atttagatca attttagttc ttttttatat
     7981 ttctatgatc tgctcattta cttttatatg atggcttaca gtaacataaa taaatatgat
     8041 aatcgctggt agtttatcca agagtactca ataaaataca aaatggattg ttcaagcgcc
     8101 tatcataatg ataaaatgaa acaaataaac gatacaagga ggaagagact ttgagtaatg
     8161 gcagaacaat tttttcattg taaaaattgt tcagttgtta atctatggga tttcggtagc
     8221 atgggcattt ttttatagag gaatcacacc aacctggccg ttttatctct tgttagtggg
     8281 aatattagta ggaaattttg cccctcttca ctatcgtacg aacttttttc caactgattc
     8341 tggccttttt cttaaaacaa agacgcgaaa attagaaaac attattgaaa tgacaattac
     8401 ctgtataatc attttcttag ttatattcct aaacgtcttc taataagaat ctcttaaaat
     8461 tagcttgtta cagttagtta cctagtttat ataacacagt tatcttatct tccttatcaa
     8521 catcttttgc caactctttg tcttaaattc gaaacatata agcagagcta cgaacaccaa
     8581 gactgtttcg gctctgtttt ttgcatcaaa ttcactctta tatagctgat aatctcggct
     8641 ctttaaaaga aattattttc gcttcatttt attataaaaa ggctaggaac cttgatgtta
     8701 tcaggttcct agcctttatt taagtattac cccacagacc cttccatata gatttttaaa
     8761 ttacacacta gtttaaacta aaacaaacaa ggaaaaactt accatttaat caaaaaatta
     8821 gctcatatga atatattaga atgtaaatta gactggtcaa aatctggtca aaaaagagga
     8881 cgaatacagg tagtcctctt ttttgttatt ttgatattct aaatcatttt ttattggatt
     8941 attcccttgt tcgatataga cccaaattga tctatcaata attatcaaac tgagtcatat
     9001 agagacaaaa atttcaaaaa tgacctgtta aatggtcatc gaatatcatt taaaatcaat
     9061 acgacggagt cagacacgga gtcaaaacaa gcccgctgag agtaaaaaat atacagtccc
     9121 ataggtaaag tgccacagga ctgtatattt ttttatttga gattacctga aatgattcca
     9181 tttaattttt atctcatttt ttcctactag ttagtatcaa atactctcct attttctcaa
     9241 taaactattt tgggttacat ggtatctgaa acagctaaaa ccttgtcatt atagcaaaaa
     9301 atcactttat ctccgtttca tttcagatac atttcactta agcggattcc aaaaaaacaa
     9361 aagaaaaagg aacccctagt tagcctatgc tttttattgg ttcctctcaa aacacggtca
     9421 tataacaacg gggtggggta aatgaatgaa aaaggtggag gaaacattat tcaatagctg
     9481 tcttaaatac ttcgttataa aatgtgaaca aataaaagac atctatccct attttctaca
     9541 cttccacttg actaccatct ttgaatcgta caattttctt aactcttctc gtttacctca
     9601 attcattctc aagtggaatc aactcatcat ctaacatttt acgccatgct cgcttcattt
     9661 cttgtgggta tttaaatggc ttcgcttctg gatgtttggc tttatatcct tcgtaatcct
     9721 tactgttgat aattgctttc atattaggaa ttggatcttc acctggtaga tattgcagat
     9781 tagaagcatg taattctttc tcagaaacaa accactcatt ggaaaagaca tgaatcaaat
     9841 catcactcgc ttgtgtaaaa tagcgacgtt taatgacaaa gatatcttca ttactatcta
     9901 aagtccccac atcaaatgca tttaaaattt gtcggtaaac ttctttgact ccttctgttt
     9961 tattcaattt agccaaagct ttttcaattt cttctcgtgc atctgaacta ttcgcagcat
    10021 aagttcctag taattgatca atataagttg aatcaatatc atacaactta gtggtatttt
    10081 cactataaaa ttcgatcgtt gaaaaatctt ctccttcttt ttctggttct tcctctatta
    10141 atgaaccctt cacggtctcg tacacgccaa tttgttcttc caaaagttga atttgattgt
    10201 tcaaagttgg agatttcacc atgtcatcat tgtaatcgtc ataagtcact aacgattcat
    10261 aagcacgatt caattcttga aatgctttga cgtactcgat acggatttca agtggcgtat
    10321 gttcatcaat ggattccatg gatgaaacct cttttaactt accatatgct tgtttgaatc
    10381 tttttttgga ttcctgataa cttggataaa tcaaacctga ttcttctttt gcttttgaat
    10441 acagttttgt cgcatcctcg acattcttct ccattgtcgc tggcttacga aacgtcacaa
    10501 tcaatccttt tgtcttatca ggatacgtac gattcgtacg tgaaaaagct tggatcaatc
    10561 ctgcatactc tagattacga tccacaaata gggtttgaat cgtaggggcg tcaaaacctg
    10621 ttaatagacg atccactaca atcgctaaat cgatttgttt cccaaattgt ttgaattccg
    10681 ctctttttcg tgccaaacga ttattgatgt ctccgttata acgctcaatg tctgctaatg
    10741 accaggaagt atcataatac tgattatatt cctcaataat tttttgcatt tcttcttgtt
    10801 gggcacttga atctcggcta ttttcttcta atgaataggt aatagcgatt cgtggaaaat
    10861 caggatcctc catcgttcgt ccttcacgaa tgagctgatt gggaaactct tttgttaacc
    10921 aatcaggctc tttcgtcatc tctttgatgg cccgataata ctttttggcc atgtcaatgg
    10981 aactcgtggt taagattgca gatttcgttg gcctgccatt tcgaaaatca aattttgtat
    11041 aggcattatc tggacggaac attttatgaa tgactttttg gatatgttca tctgcttcaa
    11101 aaacagctgg gtccaaataa ctttcttttt tgacaggttc catttgatca atcatacgat
    11161 tgatctgttc tgatgaatac tctgcatatg tttctacttc ttttaatttc cgatagattt
    11221 tattctctag tgaagtcggc tccacggtgt tttcatgctc tacttgaaat cctaagacag
    11281 agccatcttc tagcgcattc ttaatggtat aggtatgcaa gacctctcca tactgatcat
    11341 gggttgtacg tgccaattgc cctttggctt gtttccgatt ctcaggaaaa atcggtgtac
    11401 ctgtaaagcc aaaccaagtg gatttcggaa acattttttt gatttcttcc atattttcag
    11461 cacttaacgc tcgatgacac tcatctacta caaacacgat atgttggccc attaattttt
    11521 ggaagcgatt ggttcctttt ttctcttctt gtttctttgc atatttcaac gccgcatcta
    11581 gtttttgacg ggttgtaatg attacaacat ttgcattggc atctgccaac agggtttcac
    11641 ttaattcttt ggcacttccc gttccaacga tcaagctatt cgctttggcg ttcccggaag
    11701 aaatcccagt attaaattcc gaagcaaatt ttgtaaactc tgtggtggtt tgattatcta
    11761 aatctttgcg gtccactaac atgatcgttc gatcgatccc cgattttcgt gctaaaagct
    11821 tagtagatac aaaactagtc aacgtctttc ctgaaccagt cgcatgccac acataccctg
    11881 attgatgttt atttgcggca ataaacaagg cttgaatcgc atgtacttga taaggatgta
    11941 acaccatgag ggttttatta tcttgatctt cactgacgat tgtataatcc gcaatcaaac
    12001 gatgagcatc cgggatattt aacacttgtt tacaaaactc atataagttt tctacttttt
    12061 cattgtcttt cgttcgccaa ctaaataaaa acttagggtg caagtctttc ggtaaggcat
    12121 ttgcaaaata ccgagtggtt tgttcattgg aaaccacaaa caactgtaag gtcgaaaaga
    12181 tattgttccg aaacatacct tcttctgcat attttttgat ttggttaaat gcctgataaa
    12241 caccatcttt tgcagttact tgtttcagct cgatttggac aatcggtaat ccattgatta
    12301 ataaggtgac gtcaaaacgt cgatcccgtg cttctatgtt acttccacgt tttgcaattt
    12361 gatggaccac ttcataagta gagattcctc caccaatgtc ttgattggaa taaaggataa
    12421 gtgagacaga acccaattgc gaatcttccc gttcaatcgt gatccgagcc atcccatttt
    12481 caccttttaa ccatttcgca gcatcaaatg gggttttcgt tcgcagcagt aattccgttt
    12541 tgatcgtttc aaattcttta tcggtcaaag gaaaatcatt cagttctgct tgattatttg
    12601 agataatttt ttggcgtaaa ttgacccaaa ggtcttcttc tgattttaga tccggacgat
    12661 acgtccactg attatgccct tctccaagta cacgaatcaa ctgttcttcg acttctgctt
    12721 cctcacggtg actaattttc attcttcttc cctcctagac aaacatcttt tgtaagaagc
    12781 tttttttcgt ttcttttagt aaatctaact tacgttgatg aagagcgatc gtatcatcta
    12841 gctgtttgaa gaaagtaccg attttttgtt gttcatcctt tacaggaacc ttaacactga
    12901 tattctcaat atcagaactg ttataagaag gcaatgcccc tacttgggag tatcttggca
    12961 aatttatagt ttcaaacaat attttaccaa aatagatatc ccaagtatta ttaaataaat
    13021 aagccatggt attgttatct attaagaaag ggcttgtgac caaacgtttt ctattaagca
    13081 ttattgctgc gccaacttta gcaaatataa tcgctggcac atcttttatt ggcttccatt
    13141 ttttacgctc aatttgctca ttagatacat aatgatttgc atttctcatt tcatactcat
    13201 taccaatgtt attcatgtcg gaaactttaa aaaatggagt accttcagaa ccaccttgct
    13261 cggcatcagg aaatccaatt cccgattgag ttttacctaa ttctcccaac ttacgctctt
    13321 cccaatcttc cgtaaaacca ggaaaccgga tttctggcac ttttgctccg ttttcaggga
    13381 acattttttg taagaatcct tttttcgttt ccttcagcaa atctaactta cgttgatgaa
    13441 gagcgatagt gtcgtcgagt tttttgaaga atatgccgat tttttgttgt tcttttaaat
    13501 cattgggaat atagaatact gtatctgaaa cttttttcca gtctgaacga ggcatttttg
    13561 ttccagatgt atcatttgca gccttttgat atctatcagc ttgaataaga gaataaataa
    13621 agtccgagtc gctcttctta gctctaaaaa cccagaaatc cccaatcgct acgcctgtaa
    13681 aagttgcctt gagccaattt tttaaatatg gacgtaactt tccatataga atatcatttg
    13741 gtaaaaattc aatccctttt ctattatcaa atttctggct cacatcttta ttcagtctac
    13801 cttctcctgc cacgatatct tcaaattcaa cttttggaag tctactggag tttgtacttt
    13861 tattaagtct aacaactaaa tcaattaact tacgctcttc ccaatcttcc gtaaatcctg
    13921 ggaaacggat ttctggtcgt gtatcattgc tcatgtttga acacctccag cgcaccttgt
    13981 aaccacattt cgttttcagg tgttgtttgc agggaagaga tagcttctaa aagttctttt
    14041 tctagcactt gctgttcttg tcgtatcttc ttgatgtcat ttccgacatg aaccatatca
    14101 attggttctt cttcttcgaa agtatctaca tagcgtggga tatttaagtt atagtcattt
    14161 tctttgattt catcaaaggt tgccaaatga gcgtatttct cgacatcttt tctttcagcg
    14221 taggtttcga ggattttttg aatgttttct tccgatagtt tattttgatt tttcccttta
    14281 acaaattcac gactagcatc aatgaataat acatctcgag tttgacgatt cttcttcaac
    14341 acaatcaccg tcgttggaat cgatgtccca aagaacaagt tcgcaggcat accgatcaca
    14401 gcataaatac tgccatcttc tagtaatttt tgacggatga ccccttctgc agcgccacgg
    14461 aataaaactc cgtgtggtaa gacgatggcc atggtacctg tttccttcaa atgatagaac
    14521 ccatgaagaa gaaacgcaaa atctgctttg gattttggcg ctaatttccc ataacgatta
    14581 aaccgagaat catctaagaa agtcgtatct gctgaccaat tagccgaata aggtgggttc
    14641 attactactg catcaaatgt gtaaggttca tctgttggcc agtccttatt caacgtatcc
    14701 ccattgcgga gattcatttc ttcggcgtcg acaccatgta aaatcaagtt catttttgct
    14761 agattgtatg tcgttgtatt tagttcttgc ccatgatatt taacgttatc tgggtgtgtt
    14821 aagtagttac gtacgtttaa catcaatgaa cctgaaccca tcgttggatc aaaaacacta
    14881 aagaatcgtc gttccttttg atcgagcgtt acgatttgcg ccatcatatc agaaaccata
    14941 tgaggtgtgt aaaattctcc ggctttcttc cctgcttctg aagcaaattg actgatcaga
    15001 aactcatacg catccccgat cacgtcccca tcgtgttcta aaacatctac atcattcaat
    15061 ttcttgatga cttcggtaat cgtcacattt cgttgttgct catctgttcc tagttttttt
    15121 gattggagat ccacatcatc aaataaccca ttaaattgat tgtaggtaga tgccaattgc
    15181 acaaaggctt tgtttagatc gttcaattgg aacgttgctt gttttgcttg atccgctaag
    15241 acgttgaaaa gatactctgg tgcaattgca tatcccaaaa tatcaacgat tgtggcaatc
    15301 agatcttctt ttgattcttc atctgaaagt aattcacgat acaacattgt ttgtttgctt
    15361 actgtgtcat attcctctaa ggattcatct gctaaaagaa ccacttgttc caacaatcga
    15421 tcggataaat atttatagaa aatcagtccc aataaataat ttttatattc tgacgcatcc
    15481 attttactac ggagattatc tgccgcacta aataattttt gatttaattc tgcacccaaa
    15541 aagatacact cctatctctt atttaaagtt gctatatacc ctcttatttt agcatacccc
    15601 cttttataaa aagcaaaaaa aaaagaaaga aacttattct tgctaataaa ctacgcgaaa
    15661 ggagtctaac gttgtttgat ataacttaga ctgatcgtta acttattttt tatatttcta
    15721 catagttatc tttagaacca tttcagatac atatgaaaca attacatatg attttttcat
    15781 aaaaaaacag tactgtctag tagtataaaa tatacaaatt tcttaaaaat tttttcacta
    15841 aaatcactac ctgaaacagt ctaaaacact tatatatcaa cgtttaatga aactatctcc
    15901 gtttcatttc agatacaaat aaatatagtc gggctccaaa tccgaaaaaa aataccccca
    15961 gtagcttatc ctaagctact ggagatgtat aagtacggtc atataacaac ggggtagggt
    16021 aaataaatga aaaagatgga agaatcatta ttcaataact tttttaaata cttcgttgta
    16081 atcagttacc tgtccgttct taaataccac agaataatct ttttacccat tttcaagtaa
    16141 ccgaagtgga atgtctttac caacttgctc tgtcactgca ttactgatac ctgttagatt
    16201 agctaataaa tctgataaag attgagcatc tgtagaaatc tctgtatcag tatttatcgt
    16261 gattccttta tcttcattta caagcttcca agtaggtggt atagctgtgt atgtttcgat
    16321 gaatgaatca attctttcat ctatcgtctt cccagtatct acttctgtct cattactctt
    16381 agatgaatcg attctttcat ccatcgtctg ctccgtaact gcttctgtct cattattctc
    16441 accggaaact ctcttcacac ccaaacttat atattgtcca tctttagtgt gcatagttaa
    16501 aattcccacg cttttactaa taaattcact ataaccagtt ctttcaatag agacttcaat
    16561 gtatttcaca ctatcatact caaaagaaaa atagacatgt aaaagcattt tgttgtttac
    16621 atctacataa taatcctttg actctacttg agaccttcct atacggaata cagctttact
    16681 gtctgatatc tctataccag catccttatt attaatctgc caatctccaa gtagctcttc
    16741 tggcaagcta gtagtttctt gtgaacactt taccacttca ctggtagagg tcgaaacatt
    16801 cacctccgca ctgttagaag aattttccaa ggaatcagga gccttagcac aaccaacaag
    16861 tctttatata ttgtgcagcc gatattttct tcattcagta cacccttgaa atatgcagtg
    16921 ttagataaag cagttcgtcc tgatttgctg aggcacccat ctcttcttga acgtactcct
    16981 tgattttcaa ggccgcccga tactctttcg gaaaacgctg cttcactgaa gccagcaaaa
    17041 aatcatcctt ctccggcaac tcttccttct taatcattcg ggcaataaaa aactgtaaat
    17101 gcgtcacaaa tcttaagtaa agcatcgaat ctttatcaac ctttttttcg ggaaacagat
    17161 atcctagcat agccaagata tcctttagtg ctcttaccga gagcatggtt tcttccatat
    17221 ttgcttgttc actttgggca tttacaatgt gaaacgcaat gtttccagcc tcctcttctg
    17281 gcaactgaac attcattttt ttgttgatca attggatagc atagcagccg atctcaaatt
    17341 cttttgggta atacttttga atttcaatca gcaggcgatt ttgaaaaaca atgccttttt
    17401 gactgcgttc aatggcatgc ttcaagtgat caaccaaggt aaaaaataga cttttattca
    17461 gcttaaagtc aaacttggcg ttggcataat cgataattcg cttgacgcaa ataattagat
    17521 catccggagc agcctcaaac agtttaatgt aatccttttt tagagcatca gaaagtgaat
    17581 ctaatttaaa tactttttgg attttgtcag ccggaaccaa atcgcctttc tttagttgaa
    17641 atccaatccc tttccccatc aaaattactt ctttgccttg cttatctaag caaagaatta
    17701 aactgttgtt taacgtttta attactctca ttagattcac cgttctctct aagctaagcc
    17761 atttcttgcg attacttttt gataccaaaa gaagctttct ttttttattc gttttaattc
    17821 tttaagattc tcatcggttc ggtcaacata tataaaacca taacgcttat tgaagccttg
    17881 atgggtacta acaacatcaa tcgctgacca aggtaaataa ccaaaaacat ctacaccatc
    17941 tgttaaagct gcttgaatag ccagaatatg tttggctaga taatcaattc gatcctggtc
    18001 attaattcgt ctatcttcct caactatgtc gggtgcccca tagccatttt cagtaattaa
    18061 aataggtaaa tcatagcgat cgtacaattt cctcaatgtt aatcgtagtc cagtagggtc
    18121 aactacccag ccatatggcg ttttatctac ataaggattt tcagctgccc ggtagacacc
    18181 ttcttctccc aacatgatct gttgatcccc cgctctagcg gaaacatctg atccgtcatt
    18241 tttgctggca gcgatggtgg cagttgaata ataattaatc gcaataaaat cgggtttacc
    18301 ggaggataaa attgcctgat cctctgcctc aattttagga tataatccac gatcattcaa
    18361 atagttttca aacaaataat tgtattttcc ccgaactgct acatctaaga aagaccagcc
    18421 tctcaatgtt tcccaattat gggctgcaat tgcatcttct ggactggagg tagcttgata
    18481 catagccgtt aaattgattg ctggaccgat ttttccttta agattcaact gatgatacaa
    18541 gtgaattact ctagcttgag ctaataaaac atggtgatta atttgaaaga gttctttttt
    18601 tgaaggcagc tctccacttg gtggcaaacc aatcgctcca ggatgaagga tcatcgtgtt
    18661 ttgctcatta attgtcagcc aatagttcac cttgtcacca tactcagtaa gcaatacctg
    18721 tacatagtcc acaaaataat cgatagttgc tcgatttaac caaccgccct gctcctctag
    18781 aaaataaggt aaatcgaaat ggtacatggt gacaatcggt tcgattccct gattcaggca
    18841 ttcatcaatt acttgatgat aaaaagaaat tcccttttga ttggttttat tattttcaat
    18901 atccataatt cgcgtccaag cgatggaaaa gcgaaaagct tttaagccta attctttaaa
    18961 cagctgtata tcttctttat agtgatggta aaaatccgag gcaacttcaa aattagctac
    19021 cccttctgta tgctgatact tgtcaataat agacggttgt ttcccatcct cctgataggc
    19081 accctctgcc tggtaggcac taatggaggc accccataaa aacttctctg gaaatgctga
    19141 aagctgtttg tattgcacaa aaatcctctc cttaactaat ttgcatcaat ggttcgtgtt
    19201 cctttaagct tccgcttgct tcactaattc ctgcgtaatt ttcactgttg gtcactacca
    19261 caatcactgt atcatcgtag ccagcgtttc taatggcagc gaaatcggcg ttgattaata
    19321 attgtcctgc tgacacctga tctcctgctt ttacaaatac ttcaaagggt tcccctttta
    19381 aattcacggt gtcgatcccc acatggatca ataattcaat accttcttta gaacgtagac
    19441 caatcgcatg tttagattct aaaatagtaa tgacttctcc ctcaacaggt gaataaatgc
    19501 tgttttcttc tggatgaatg gctacgccct ttcccaatag tcccttagaa aagacagcat
    19561 cgttcacttc agaaatagga cacacggttc cttttaccgg attttcaaca atgactgctt
    19621 cggctattgc cgtttgctct gattcatcag aagtatcgtc aaatccaatt agataagcaa
    19681 tgataaaggt tgcaacaaag gcgattacac acgtaataat tgcgtgaaca atattcattg
    19741 gattttctcc aataaaggct ggtaaggctg ctaagccagg ggaaacaaag gcatatctga
    19801 ctaaaccgct caagccagca tacaaaccag caattgcacc accaatcatg gaagcaacta
    19861 atggtttttt cagcttcaag gttactccat agagtgaagg ctcagtaatt cccattaaag
    19921 cagtgatccc agtggacaca gctagctgct tcaactcttt gtttttagtt ttcgcggcta
    19981 cagcaaaggt agcacctgat tgagcaatat tagaagccag cattcctggc ccattgatca
    20041 tttcagaacc cgtactgctc aattgcatag tagcgattgg cgtcattgcc caagctgtac
    20101 ccgtaaccac caaaaatggc tgcaaaccac ccatcaaaaa tggaattaac caagctgctt
    20161 tgccgttaat ccattcagcc cccattgcta taagatcgtt cagcaacgtt ccaaacggtc
    20221 caatgacaac caacgctaaa ggccccataa ttaaaaatac cagcatcggc ttagtaaaga
    20281 atttaataaa cgaaggcgaa attcgatccg caaagggctc tacataggac atgatccaaa
    20341 cagtaaagat aatcggtaaa actgatcccg cataatctgc agctaatacc ggaattccta
    20401 gaaaagaaac ggcatcgcca gtagaaaaaa gctgtgaaat atttggatga agcaaaatgc
    20461 cagcaacagt aatcgccaaa attgggttga catcaaactt tatggctgcc ccataggcta
    20521 atagtactgg cataaaataa aaggctgcat cagcaatagt attcaaaatg atgtaagttt
    20581 gactactgtc tgatagtaca ccagtcaaag tcaagacggc caaaatggct tttaccatcc
    20641 cggcacctgt tatagctgga atcatcggtg taaaggtggt agaaatgaca ctaatcaatc
    20701 ttgaaataat actttcttga ttgtctgaag aggggccctt tttaattgaa gttcccactt
    20761 ccttttgaat ttccttgaag gctgtttgga cttcattgcc aatcaccact tggtattgtc
    20821 caccgctatc caccacacta attacaccaa gtgttttttc taaggctttc gtatcggctt
    20881 tccttttatc tttgagttca aaacgcagtc tggtggcaca atgggttaag ctgaccacat
    20941 tttcttttcc cccaacctgt tgcaatacat ttcttcctac ttctctgtaa tccattattc
    21001 tctctcctta aagcagtaaa aaagaccaag tcaaaccacg ccccaatcaa cattgaagtg
    21061 ttagtttgtc ttggtcttgc ctgcataatc agtaacatgc caataacgtt attttgctgt
    21121 aatccaataa tagcacatta tgatagcgca atcaacaggg aatttaattt tttatctttt
    21181 cgtttgaccg tatagggtaa tataacagtt agatcacatc aactagggta tatctgcgta
    21241 tacttactgc taaaataagt atatctaata ttaactatac cagtaaaacc attcctacat
    21301 aaccagcggg aaattcccaa aatcgtgaaa gcatcaaaaa tgcatataac ggatcacaca
    21361 acttcaacaa ttctgctctt gggaaaaatt gatgaatttg gtgagtaaag gatggaataa
    21421 acagcattcc aacaatatag gcaacaatag tgatacttgt ttttttggta aaaatcagta
    21481 agcaatagcc aatttcaatc attccgagat ataaaggtat caatagaatg atttgggcta
    21541 gtattcttaa aaattaacta gcaaatgttt aaactgattt atttctaatc tacatgtagt
    21601 aagtatttca attcca
//
LOCUS       DACDAF010000047        21032 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.047, whole genome shotgun sequence.
ACCESSION   DACDAF010000047 DACDAF010000000
VERSION     DACDAF010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.047"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            56..508
                     /locus_tag="IVZ69_001630"
     CDS             56..508
                     /locus_tag="IVZ69_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183715.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            522..1211
                     /locus_tag="IVZ69_001631"
     CDS             522..1211
                     /locus_tag="IVZ69_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183716.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1336..3687
                     /locus_tag="IVZ69_001632"
     CDS             1336..3687
                     /locus_tag="IVZ69_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HAP8183717.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3767..4162
                     /locus_tag="IVZ69_001633"
     CDS             3767..4162
                     /locus_tag="IVZ69_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183718.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4487..5104
                     /locus_tag="IVZ69_001634"
     CDS             4487..5104
                     /locus_tag="IVZ69_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8183719.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5145..5444
                     /locus_tag="IVZ69_001635"
     CDS             5145..5444
                     /locus_tag="IVZ69_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183720.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5478..5645
                     /locus_tag="IVZ69_001636"
     CDS             5478..5645
                     /locus_tag="IVZ69_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8183721.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            5666..6007
                     /locus_tag="IVZ69_001637"
                     /pseudo
     CDS             5666..6007
                     /locus_tag="IVZ69_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(6087..7379)
                     /locus_tag="IVZ69_001638"
     CDS             complement(6087..7379)
                     /locus_tag="IVZ69_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP8183722.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSECRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
     gene            7446..7757
                     /locus_tag="IVZ69_001639"
     CDS             7446..7757
                     /locus_tag="IVZ69_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8183723.1"
                     /translation="MFWKIKKMLVSSTNIKKYRAKKIKERQAQGIEIAKKKGKFKGRQ
                     HKFKENDPRLKHAFDLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVDQRKNNEKRD
                     S"
     gene            7757..9901
                     /gene="topB"
                     /locus_tag="IVZ69_001640"
     CDS             7757..9901
                     /gene="topB"
                     /locus_tag="IVZ69_001640"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP8183724.1"
                     /translation="MSTVILAEKPSQALAYASALKQSTKKDGYFEIKDPLFTDETFIT
                     FGFGHLVELAEPGHYDEKWQNWKLESLPIFPDRYDFEVAKDKGKQFKIVAELLKKANT
                     IIVATDSDREGENIAWSIIHKANAFSKDKTFKRLWINSLEKDVIRSGFQNLQPGMNYY
                     PFYQEAQTRQIADWLIGMNASPLYTLNLQQKGVQGTFSLGRVQTPTLYLIFQRQEAIE
                     NFKKEPFFEVEASIKVNQGSFKGVLSPTQRFKTQEELLAFVSSKQAKIGNQEGIIADV
                     QTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLKAMQGLYEAKLLSYPRTDTPFITE
                     NEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDGSKVQEHHAIIPTKQVPTESALAK
                     MDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKVADLLFQSIGKTPKQEGWKILFKQ
                     QTKEEKEDVQTLPLVIIGERAEVGVKSVEKETQPPKAFTEGTLLTAMKTANKTVDDEE
                     AIKILQEVEGIGTEATRASIIEALKQKEYIQVIKNKLVVTEKGKLLCQAVESQHLLTS
                     AEMTAKWETYLKKIGKREGNQENFITNIKKFIVHLLEAVPNDIEKLNFSDYQEQKEKE
                     AEKSIVGKCPKCGNNIVLKKSFYGCSNYPECKFTLAEHFRKKKLTKTNVKELLEGKET
                     LVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            10021..10260
                     /locus_tag="IVZ69_001641"
     CDS             10021..10260
                     /locus_tag="IVZ69_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013646120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAP8183725.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            10309..10393
                     /locus_tag="IVZ69_001642"
                     /pseudo
     CDS             10309..10393
                     /locus_tag="IVZ69_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
     gene            10518..11255
                     /gene="erm(B)"
                     /locus_tag="IVZ69_001643"
     CDS             10518..11255
                     /gene="erm(B)"
                     /locus_tag="IVZ69_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP8183726.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(11452..14418)
                     /locus_tag="IVZ69_001644"
     CDS             complement(11452..14418)
                     /locus_tag="IVZ69_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAP8183727.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            14564..15139
                     /locus_tag="IVZ69_001645"
     CDS             14564..15139
                     /locus_tag="IVZ69_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8183728.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            15353..16048
                     /gene="vanR"
                     /locus_tag="IVZ69_001646"
     CDS             15353..16048
                     /gene="vanR"
                     /locus_tag="IVZ69_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAP8183729.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            16026..17180
                     /locus_tag="IVZ69_001647"
     CDS             16026..17180
                     /locus_tag="IVZ69_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP8183730.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            17395..18363
                     /locus_tag="IVZ69_001648"
     CDS             17395..18363
                     /locus_tag="IVZ69_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAP8183731.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            18356..19387
                     /gene="vanA"
                     /locus_tag="IVZ69_001649"
     CDS             18356..19387
                     /gene="vanA"
                     /locus_tag="IVZ69_001649"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAP8183732.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAFITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            19393..20001
                     /locus_tag="IVZ69_001650"
     CDS             19393..20001
                     /locus_tag="IVZ69_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAP8183733.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
     gene            20536..>21032
                     /locus_tag="IVZ69_001651"
     CDS             20536..>21032
                     /locus_tag="IVZ69_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HAP8183734.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT         7045 a         3487 c         4247 g         6253 t
ORIGIN      
        1 attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga gaatcgtgaa
       61 aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct attttctttt
      121 gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag ctgaacataa
      181 taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag aattgtataa
      241 agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa ttagtgactc
      301 agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca aatccgaatt
      361 agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt ccaacgctat
      421 ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa agcagataaa
      481 agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag atttttggtg
      541 tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct gctgagaaag
      601 aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt gaagaagaag
      661 ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa attgtatcta
      721 tggataatcc agatataatt caaggttcat ataattcaga aactgatcct gcttcagttt
      781 cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt gaaactactc
      841 caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac cttcttgtac
      901 tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg cgttttggag
      961 gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa tcctacattg
     1021 acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt tctattcaag
     1081 gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg cctggttgga
     1141 caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat tatgttgttc
     1201 aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta tttttagttg
     1261 ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg ttcggcaaga
     1321 aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct aaacaagaaa
     1381 tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg gtggcctaca
     1441 atctatggac ttattgaagg actacaagta gaacttggta ttactaatct agtagctaat
     1501 tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg gggcaaaaat
     1561 ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg gattaatcca
     1621 ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga gttgcagact
     1681 gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg ggccaaagcg
     1741 ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat tagaaaaatg
     1801 cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg tgatggtatt
     1861 tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact aggatattct
     1921 cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta tcctgtgtct
     1981 gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt taatggttat
     2041 tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga agtactggca
     2101 ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt tgtaataaaa
     2161 ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga tacttctacg
     2221 caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat agttggtaga
     2281 tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct aactacagag
     2341 gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca agatggaggt
     2401 gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa ggctatagat
     2461 gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt tgatctagac
     2521 atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt atctgctgta
     2581 atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg ttctcaaata
     2641 atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg ttatagtggg
     2701 aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga atttaccata
     2761 ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag agatagcgga
     2821 tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata caatcagaag
     2881 gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct tgataatcct
     2941 tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc atgggacatc
     3001 atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag gaataaatta
     3061 actaatagcg agggcctgta taattatttt atagatccta atactggttc aataataggt
     3121 ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac aatcaatgat
     3181 agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg tgaagttaag
     3241 aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc tgcaggtgga
     3301 acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta taccttagca
     3361 aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg tgataagggt
     3421 gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga taaaatcgct
     3481 tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg tgtagggata
     3541 atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt tacttatctt
     3601 gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat tattcaattt
     3661 caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt gtccttttcc
     3721 tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga tgattatgga
     3781 agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat gtggaattat
     3841 ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca agatagtaga
     3901 ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt ttgaaagagt
     3961 accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag agtctccaaa
     4021 tgaaatgtgg tttgaagtta cagttgaatc aagcgacttc aaagaaaaaa agaaagaata
     4081 caattatatt gtaaaggcaa aagtatcaaa aagatttatt tttaacccta aattagaaat
     4141 atatagtgtt gtaatagaat aatagtgtta aaaaaattgt aaaagttaaa gaagtcaaat
     4201 tctgatgtga aaaataaaat ataccatgga agacataaaa gaaaaactgg ataactagtt
     4261 tatttaatgg cagaccgtta aggcctgcca tttttatgta ttttagcgga ataaatataa
     4321 tcatgcggga gtgtaaactt actgtttcaa aaagtatact ttttgacatg ccttgatttt
     4381 ctttgtttat gtatggcata ataaccacat aatacaattt gaaacgtttc tgatttaatc
     4441 tgattgtttt gaaacaattt tagtgaaaaa agggtagata aaaacgatga gaaaattttt
     4501 ttatatccgg gtcagtagtt atgatcaatc gatcgaacga caactgattt ccgcgaagga
     4561 attaggaatc cctgaagaat atatatttgt agaaaaagcc agcggcaaag attttaaacg
     4621 ccctgaatat caattaatga aacggatgtt tcgaaaagga gatttactct atctacaatc
     4681 attagataga ctaggcagaa ataaacaaat gattttagaa gaatggcgag aattaactaa
     4741 ggaaaagcag attgatattt ctgtgttaga catgcctctg ttagatactg ctagttacaa
     4801 gcaactagat gggttagaga cgcttatctc tgacttaatt ctgcaattac tcagctatat
     4861 ggccgaagac gagcggaaac gaattaatag ccggcaaaga gaaggcgtag aagctgcgaa
     4921 acaaaagggt gtaaaattcg gcagaaagaa aattgcttta cctcctgaat ttcctgcgat
     4981 ctattctgac tggaaagcag gaaagataac tgcagtctat gctatggatc aattgggcat
     5041 gaaacgaaat accttttatc gacgggtgaa agaatatgaa cataccttgc accacttttc
     5101 ttgatagata taacagctat tagacgggaa gggagagttt gaaaatggac ttaacgaatc
     5161 aaagggtcgt ttttactgga acgctgcagc aaatgacacg aacccaagcc atcggtttgg
     5221 ttcactcttt aaacggccat tgtcaatcaa gtgttacttc aaaaacaaat ttcctggttt
     5281 gtggtcagta ttctaagtcg ttgtttgatg attctctcta tacaaaaaag gaacaaaccg
     5341 cgcgggactt gattgcgtta ggtcatgaga ttaccatttt atcagaagtc gaattttatg
     5401 cgttaattag tcaacagttg aaagaatggc aacggtattt ataatcgtta gtaaaattta
     5461 caaggaggaa aatttttatg aagcgaaaat cttatgatcg ttggggcatt gaaataacta
     5521 gttttaatcg aaatattgct tttcacgtgg agtgtgactg tggggaatta gcaaaaagtg
     5581 tttatcaaaa aaattacttt tactgtccta aatgccatcg ccgatacggg gtacatggaa
     5641 catagaaacg aaatagtgcg gtagaaaaga acagaactta gatcggcaat tacaagcgtt
     5701 acagggcgtt tctaaggtct tttcagacaa attaagcggt caatcggtcg aacgcccaca
     5761 attacaagct atgcttaact atattcgtga aggggatatt gttattgtta ctgaattaga
     5821 tcgattagga cgaaataata aagaattaac agaattgatg aatcaaattc aaattaaggg
     5881 ggcaaccctg gaagtcttaa atttaccctc aatgaatggt attgaagatg aaaatttaag
     5941 gcgtttgatt aatagccttg tcattgaatt gtacaagtat caagcagaat cagaacgaaa
     6001 aaaaatggct ctttgtcaaa tgatgttggt aaagagaaat cttagaataa ttggagatca
     6061 agtggatcag ttcctcttga tcttttttag ttgaaaatca atgcgttgcc atgacgaatc
     6121 atgatgcgca atttgaaatt ataaaagcta cgaaagccat atgcatttcg ttttaacact
     6181 ttgatatggt tgttcagaca ttcaagtggg ccatttgaat aactttgttg taaagcattt
     6241 ttgatttgtg gcagaaattt ctggaacgtt ctcaaggtcg tctgatagcc ttcgggaagc
     6301 atgatattat tggtaagtag ttcttcaaac gatacgtagt ctcgttcctt tacagcgtaa
     6361 agaaagtctt gatataactg atagcctaca cgcaaagcag ggctcccttt cagtaagcga
     6421 tccacaatat cggtctctgt taaatgagct ttgaagccag gtcgccaaag gcgtcgagta
     6481 taatcaagct tgcgttcatc tttttgaaga agtttccagt atctttttaa ttgcttacct
     6541 aattgatagt gtttttgttc tttgcttttt aatagttggt tcgtttcttt gattcgatga
     6601 ttgcgaaagg tacgaccaat atgttggacg atgtgaaacc ggtcaataat cagctgtgct
     6661 tttggaaaca gctttttaac gagcgataca taaggagcgt acatatcaat cacgatccat
     6721 tcgaccgctt cacgaatttc tcgtgaaaaa tgactaaaat aacgttttaa aaaaggcagt
     6781 tgtcggttct cgacaatgtc caacaagcgc tgtgtttgtc catccatcat gatgaaactc
     6841 atagcacctg aaacaccccg aactgatttg aattcatcaa aacaaagtac cttaggtaac
     6901 ggtgtccgaa aaggattcaa cggacgataa aatcgcttca taatacggta aacagaagag
     6961 accgatagat ttttctgagc ggcgatctct gtcattgagg tatttttttt cagacgagtc
     7021 acgacagacc agcggacttt ctcactgatg aaacagtgtt ttttcgcaac agaagtatct
     7081 gcgacaaagg tccgctgaca agctttgcat ttgaagcgtt gctttttcaa ttcgaggtag
     7141 gtacggcatt cagaaacatc gttcattaac aaccggacgg ttgttgtacc ccaacgcaca
     7201 atatctgaag caatctggtg tttacagtgg atgcattctt gggctgtata aatcaagttt
     7261 ccacgataaa tatgacagat ttgccctttg tatttttctt ttgtgagaca attttcgtta
     7321 aaagtaactg ataagtctag aatatctaat gtttctttga taaggtgagt gtaagacatc
     7381 ttgattcctc cttttgggtt ggttcgccaa attaattcta aaggatttca aggtgtcttt
     7441 tctatatgtt ttggaaaata aaaaagatgc tggtgtcatc caccaacatc aaaaagtata
     7501 gagctaaaaa aattaaggaa cgtcaggcac aaggaatcga aattgctaag aaaaaaggca
     7561 aattcaaagg tcgtcagcat aaatttaaag aaaatgatcc acgtttaaag catgctttcg
     7621 atttgttttt gaatggttta tccgataaag aagttgaaga acaaactgga atcaatcgcc
     7681 gaacgtttag aaggtatcga gcaagatata acgtgacagt cgatcaaaga aaaaacaatg
     7741 aaaagaggga tagttaatga gtacggttat tttagctgaa aaaccaagcc aggcattagc
     7801 ctacgcaagt gctttaaaac aaagcaccaa aaaagacggt tattttgaga tcaaagaccc
     7861 actatttaca gatgaaacgt ttatcacctt tggttttggg catttagtgg aattagcaga
     7921 accaggtcat tatgacgaaa agtggcaaaa ttggaaactt gaatctttgc cgatttttcc
     7981 tgatcgatac gattttgaag ttgcaaaaga taagggaaag cagtttaaaa ttgttgcaga
     8041 acttctcaaa aaggcaaata caattattgt tgcaacagat agcgacagag aaggtgaaaa
     8101 tatcgcctgg tcgattatcc ataaagcaaa tgccttttca aaagataaaa catttaaaag
     8161 actatggatc aatagcttag aaaaagatgt aatccgaagc ggttttcaaa atttgcaacc
     8221 tggaatgaat tactatccct tttatcaaga agcgcaaaca cgccaaattg ccgattggtt
     8281 gatcggcatg aacgcaagcc ctttgtatac gttaaattta caacagaagg gcgtacaagg
     8341 tacattttca ctaggacgtg ttcaaacgcc caccttatac cttatttttc agcgccagga
     8401 agccatagag aattttaaaa aagaaccttt tttcgaggtg gaagctagta taaaagtaaa
     8461 ccaagggtcg tttaagggcg ttctaagccc cacacagcgt tttaaaaccc aagaggagct
     8521 tttagctttt gtttcttcta aacaagctaa aataggcaat caagagggga taattgctga
     8581 tgttcaaacc aaagagaaga aaacgaatag tccgagtttg ttttctttaa gtagtttgca
     8641 atcaaaagtc aatcagcttt ataaagcgac agcgagccaa actttaaaag ctatgcaagg
     8701 actgtatgaa gcaaaattat tgagttatcc aagaacagat acaccattta ttacagagaa
     8761 cgaatttgct tatttaaaag cgaattttgg caaatatagc ggttttttag gacttgatct
     8821 tgaaatggtt caaacagagc ctagaaagcg ttatgtggac ggtagtaagg tacaggaaca
     8881 ccacgccatt atcccaacaa aacaagtacc taccgaatct gcattagcga aaatggacga
     8941 tttacaacga aaaatttatg ctttagtcgt taaaacgacc gttgccatgt ttttacctga
     9001 ttacttgtat gaagaaacca agatacaaac gaaagtagct gatttgctgt ttcaatcgat
     9061 cggaaagaca ccaaagcaag aagggtggaa aattcttttc aaacaacaaa ccaaagaaga
     9121 aaaagaggac gttcaaacgt taccactcgt tatcattggc gaacgtgccg aagttggtgt
     9181 taagagtgtt gaaaaagaaa cgcaaccgcc aaaagctttt acagagggta cattattaac
     9241 tgctatgaaa acggcgaata aaacggttga tgatgaagaa gcaatcaaga ttttacaaga
     9301 agttgagggg attggaacag aagcgacaag agcaagtatt attgaagcgt taaaacaaaa
     9361 agaatatatc caagtgatta agaataagct tgttgtaact gaaaaaggaa aattattgtg
     9421 ccaggcagtt gaaagtcagc accttttaac gagtgctgaa atgacggcta aatgggaaac
     9481 gtatttaaaa aaaatcggta aaagagaagg caatcaagag aactttatta cgaatatcaa
     9541 aaaattcatt gttcatttac tggaagctgt acctaacgat atagaaaaac taaatttttc
     9601 tgattaccag gaacagaaag aaaaagaagc agaaaaaagt attgtaggaa aatgtcctaa
     9661 gtgtggcaac aatattgtat taaaaaaatc gttttatggt tgttcaaatt atcctgaatg
     9721 taagtttact ttagctgaac attttagaaa gaaaaaacta accaaaacga atgtaaaaga
     9781 attactggag ggaaaagaaa ccctggtaaa aggaatcaaa aacaaagaga aaaagcccta
     9841 caatgccgtt gtaaaaattg gggaaaaggg atatattgat tttatatctt tctcaaaata
     9901 aacataaaag ccctttaaag agggctttta tatattaatc acaaatcact tatcacaaat
     9961 cacaagtgat ttgtgattgt tgatgataaa ataagaataa gaagaaatag aaagaagtga
    10021 gtgattgtgg gaaatttagg cgcacaaaaa gaaaaacgaa atgatacacc aatcagtgca
    10081 aaaaaagata taatgggaga taagacggtt cgtgttcgtg ctgacttgca ccatatcata
    10141 aaaatcgaaa cagcaaagaa tggcggaaac gtaaaagaag ttatggaaat aagacttaga
    10201 agcaaactta agagtgtgtt gatagtgcat tatcttaaaa ttttgtataa taggaattga
    10261 agttaaatta gatgctaaaa atttgtaatt aagaaggagg gattcgtcat gttggtattc
    10321 caaatgcgta atgtagataa aacatctact gttttgaaac agactaaaaa acagtgatta
    10381 cacagataaa taaatacgtt agattaattc ctaccagtga ctaatcttat gactttttaa
    10441 acagataact aaaattacaa acaaatcgtt taacttctgt atttatttat agatgtaatc
    10501 acttcaggag tgattacatg aacaaaaata taaaatattc tcaaaacttt ttaacgagtg
    10561 aaaaagtact caaccaaata ataaaacaat tgaatttaaa agaaaccgat accgtttacg
    10621 aaattggaac aggtaaaggg catttaacga cgaaactggc taaaataagt aaacaggtaa
    10681 cgtctattga attagacagt catctattca acttatcgtc agaaaaatta aaactgaaca
    10741 ttcgtgtcac tttaattcac caagatattc tacagtttca attccctaac aaacagaggt
    10801 ataaaattgt tgggaatatt ccttaccatt taagcacaca aattattaaa aaagtggttt
    10861 ttgaaagcca tgcgtctgac atctatctga ttgttgaaga aggattctac aagcgtacct
    10921 tggatattca ccgaacacta gggttgctct tgcacactca agtctcgatt cagcaattgc
    10981 ttaagctgcc agcggaatgc tttcatccta aaccaaaagt aaacagtgtc ttaataaaac
    11041 ttacccgcca taccacagat gttccagata aatattggaa gctatatacg tactttgttt
    11101 caaaatgggt caatcgagaa tatcgtcaac tgtttactaa aaatcagttt catcaagcaa
    11161 tgaaacacgc caaagtaaac aatttaagta ccgttactta tgagcaagta ttgtctattt
    11221 ttaatagtta tctattattt aacgggagga aataattcta tgagtcgctt ttgtaaatta
    11281 taaaagaatt gttttaatgc aggtataaaa gatgaacccg caccaacacc gccaccaatt
    11341 ttagatagct ttgattggta catttttagc gctattcggg gtagcgtcag gaaaatgcgg
    11401 atttacaacg ctaagcctat tttcctgacg aatccctcgt ttttaacaac gttaagaaag
    11461 ttttagtggt cttaaagaat ttaatgagac tactttctct gagttaaaat ggtattctcc
    11521 tagtaaatta atatgttccc aacctaaggg cgacatatgg tgtaacaaat cttcattaaa
    11581 gctacctgtc cgttttttat attcaactgc tgttgttagg tggagagtat tccaaatact
    11641 tatagcattg ataattatgt ttaaagcact ggctctttgc aattgatgct gtatggtgcg
    11701 ttctctaagc tcaccttgtt ttccgaagaa aatagctctt gccaatccat tcatggcttc
    11761 tcctttattc aatcctcttt gtatttttct tcttaatgat tcatccgata tataattcaa
    11821 aataaagatc gttttttcta ttcggcccat ctcacgtaag gctgtagcta agctgttttg
    11881 tcttgaatag gaacctagct tccccataat aagggatgct gaaactgttc cctcccttat
    11941 agaatgagct aatcgcaaaa catcctcata attttcttta atgacctttg tatttatttg
    12001 tccacgtaaa atggcttcta gttttggata ctcacttgct ttatctatcg taaataattt
    12061 tgagtccgat aaatccctta ttcttggggc aaatttaaat cctaataaat gagtcagtcc
    12121 gaatatttgg tcagtgtaac cggcagtgtc tgtataatgt tcctctatgt ttagatccgt
    12181 ctcatgatgt aacaaaccat ccaaaacatg aatcgcatct cttgaattag tatgaataat
    12241 ctttgtgtag taagaagaga attgatcact tgtaaatcgg tagatggtgg ctccttttcc
    12301 agttccataa tgtggatttg catctgcatg tagtgatgaa acacctagct gcattctcat
    12361 accatctgac gaagatgttg taccgtcgcc ccaatagaaa ggcaattgta atttatgatg
    12421 aaagtttact aatatggctt gggctttatt catggcatct tcatacatgc gccattgaga
    12481 tacattggct agttgcttat atgtaagtcc gggtgtggct tcggccatct tgctcaagcc
    12541 aatattcatt cccattccta aaagggcagc catgataatg attgtttctt ccttatctgg
    12601 ttttcgatta ttggaagcat gagtgaattg ctcatgaaat cctgttatat gggccacatc
    12661 catgagtaaa tcagttaatt ttattcttgg tagcatctga taaaggcttg cactaaattt
    12721 ttttgcttct tctggaacat ctttttctaa gcgtgcaagt gatagctttc ctttttcaag
    12781 agaaacccca tctaacttat tggaattggc agctaaccac tttaaccttt cattaaagct
    12841 gctggttctc tccgttatat aatcttcgaa tgataaacta actgataatc tcgtattccc
    12901 cttcgattga ttccatgtat cttccgaaaa caaatattcc tcaaaatccc tatattgtct
    12961 gctgccaaca atggaaacat ctcctgcccg aacatgctcc cgaagttctg ttaaaacagc
    13021 catttcatag taatgacgat taattgttgt accatcatcc tcgtataaat gtcttttcca
    13081 tcgttttgaa ataaaatcca caggtgagtc atcaggcact tttcgctttc cagattcgtt
    13141 cattcctcgg ataatctcaa cagcttgtaa aagtggctca tttgcctttg tagaatgaaa
    13201 ttccaatact cttaatagcg ttggcgtata ttttcttagt gaataaaacc gtttttgcag
    13261 taagtctaaa taatcatagt cggcaggacg tgcaagttcc tgagcctctt ctactgaaga
    13321 gacaaaggta ttccattcaa taaccgattc taaaacctta aaaacgtcta atttttcctc
    13381 tcttgcttta attaatgctt gtccgatgtt cgtaaagtgt ataactttct catttagctt
    13441 tttaccgttt tgtttctgga tttcctcttg agccttacga ccttttgata acaaactaag
    13501 tatttgccta tcatgaattt caaacgcttt atccgttagc tcctgagtaa gttgtaataa
    13561 atagatggtt aatatcgaat aacgtttatt ttcttgaaag tcacggaatg catacggctc
    13621 gtatcttgag cctaagcgag acagctgcaa caggcggtta cggtgcaaat gactaatttg
    13681 cactgtttct aaatccattc ctcgtatgta ttcgagtcgt tctattattt ttagaaaagt
    13741 ttcgggtgaa ggatgacccg gtggctcttt taaccaaccc aatatcgttt tattggattc
    13801 ggatggatgc tgcgaggtaa taatcccttc aagcttttct ttttgctcat ttgttagaga
    13861 tttactaacc gtattaaata gcttcttttc agccattgcc cttgcttccc acaccattct
    13921 ttcaagtgta gtgatagcag gcagtataat tttgtttttt cttagaaaat ctatgcattc
    13981 atgcagtaga tgaatggcat caccattttc caaagctaat tgatgaaggt acttaaatgt
    14041 cattcgatat tcactcaggg taaaagttac aaagtcgtat tcacttcgaa tttctttcaa
    14101 atgatcccaa agtgtatttt ccctttgagg ataatgatca agcgaggatg gactaacacc
    14161 aatctgtttc gatatatatt gtatgaccga atctgggatg cttttgatat gagtgtatgg
    14221 ccaaccggga taccgaagaa cagctaattg aacagcaaat cctaaacggt tttcttccct
    14281 ccttcgctta ttaactattt ctaaatcccg tttggaaaaa gtgaagtagg tccccagtat
    14341 ccattcatct tcagggattt gcataaaagc ctgtctctgt tccggtgtaa gcaattctct
    14401 acctctcgca attttcattc agtatcattc catttctgta ttttcaattt attagttcaa
    14461 ttatatatca atagagtgta ctctattgat acaaatgtag tagactgata aaatcatagt
    14521 taagagcgtc tcataagact tgtctcaaaa atgaggtgat attttgcgga aaatcggtta
    14581 tattcgtgtc agttcgacta accagaatcc ttcaagacaa tttcagcagt tgaacgagat
    14641 cggaatggat attatatatg aagagaaagt ttcaggagca acaaaggatc gcgagcaact
    14701 tcaaaaagtg ttagacgatt tacaggaaga tgacatcatt tatgttacag acttaactcg
    14761 aatcactcgt agtacacaag atctatttga attaatcgat aacatacgag ataaaaaggc
    14821 aagtttaaaa tcactaaaag atacatggct tgatttatca gaagataatc catacagcca
    14881 attcttaatt actgtaatgg ctggtgttaa ccaattagag cgagatctta ttcggatgag
    14941 acaacgtgaa gggattgaat tggctaagaa agaaggaaag tttaaaggtc gattaaagaa
    15001 gtatcataaa aatcacgcag gaatgaatta tgcggtaaag ctatataaag aaggaaatat
    15061 gactgtaaat caaatttgtg aaattactaa tgtatctagg gcttcattat acaggaaatt
    15121 atcagaagtg aataattagc cattctgtat tccgctaatg ggcaatattt ttaaagaaga
    15181 aaaggaaact ataaaatatt aacagcctcc tagcgatgcc gaaaagccct ttgataaaaa
    15241 aagaatcatc atcttaagaa attcttagtc atttattatg taaatgctta taaattcggc
    15301 cctataatct gataaattat taagggcaaa cttatgtgaa agggtgataa ctatgagcga
    15361 taaaatactt attgtggatg atgaacatga aattgccgat ttggttgaat tatacttaaa
    15421 aaacgagaat tatacggttt tcaaatacta taccgccaaa gaagcattgg aatgtataga
    15481 caagtctgag attgaccttg ccatattgga catcatgctt cccggcacaa gcggccttac
    15541 tatctgtcaa aaaataaggg acaagcacac ctatccgatt atcatgctga ccgggaaaga
    15601 tacagaggta gataaaatta cagggttaac aatcggcgcg gatgattata taacgaagcc
    15661 ctttcgccca ctggagttaa ttgctcgggt aaaggcccag ttgcgccgat acaaaaaatt
    15721 cagtggagta aaggagcaga acgaaaatgt tatcgtccac tccggccttg tcattaatgt
    15781 taacacccat gagtgttatc tgaacgagaa gcagttatcc cttactccca ccgagttttc
    15841 aatactgcga atcctctgtg aaaacaaggg gaatgtggtt agctccgagc tgctatttca
    15901 tgagatatgg ggcgacgaat atttcagcaa gagcaacaac accatcaccg tgcatatccg
    15961 gcatttgcgc gaaaaaatga acgacaccat tgataatccg aaatatataa aaacggtatg
    16021 gggggttggt tataaaattg aaaaataaaa aaaacgacta ttccaaacta gaacgaaaac
    16081 tttacatgta tatcgttgca attgttgtgg tagcaattgt attcgtgttg tatattcgtt
    16141 caatgatccg agggaaactt ggggattgga tcttaagtat tttggaaaac aaatatgact
    16201 taaatcacct ggacgcgatg aaattatatc aatattccat acggaacaat atagatatct
    16261 ttatttatgt ggcgattgtc attagtattc ttattctatg tcgcgtcatg ctttcaaaat
    16321 tcgcaaaata ctttgacgag ataaataccg gcattgatgt acttattcag aacgaagata
    16381 aacaaattga gctttctgcg gaaatggatg ttatggaaca aaagctcaac acattaaaac
    16441 ggactctgga aaagcgagag caggatgcaa agctggccga acaaagaaaa aatgacgttg
    16501 ttatgtactt ggcgcacgat attaaaacgc cccttacatc cattatcggt tatttgagcc
    16561 tgcttgacga ggctccagac atgccggtag atcaaaaggc aaagtatgtg catatcacgt
    16621 tggacaaagc gtatcgactc gaacagctaa tcgacgagtt ttttgagatt acacggtata
    16681 acctacaaac gataacgcta acaaaaacgc acatagacct atactatatg ctggtgcaga
    16741 tgaccgatga attttatcct cagctttccg cacatggaaa acaggcggtt attcacgccc
    16801 ccgaggatct gaccgtgtcc ggcgaccctg ataaactcgc gagagtcttt aacaacattt
    16861 tgaaaaacgc cgctgcatac agtgaggata acagcatcat tgacattacc gcgggcctct
    16921 ccggggatgt ggtgtcaatc gaattcaaga acactggaag catcccaaaa gataagctag
    16981 ctgccatatt tgaaaagttc tataggctgg acaatgctcg ttcttccgat acgggtggcg
    17041 cgggacttgg attggcgatt gcaaaagaaa ttattgttca gcatggaggg cagatttacg
    17101 cggaaagcaa tgataactat acgacgttta gggtagagct tccagcgatg ccagacttgg
    17161 ttgataaaag gaggtcctaa gagatgtata taatttttta ggaaaatctc aaggttatct
    17221 ttactttttc ttaggaaatt aacaatttaa tattaagaaa cggctcgttc ttacacggta
    17281 gacttaatac cgtaagaacg agccgttttc gttcttcaga gaaagatttg acaagattac
    17341 cattggcatc cccgttttat ttggtgcctt tcacagaaag ggttggtctt aattatgaat
    17401 aacatcggca ttactgttta tggatgtgag caggatgagg cagatgcatt ccatgctctt
    17461 tcgcctcgct ttggcgttat ggcaacgata attaacgcca acgtgtcgga atccaacgcc
    17521 aaatccgcgc ctttcaatca atgtatcagt gtgggacata aatcagagat ttccgcctct
    17581 attcttcttg cgctgaagag agccggtgtg aaatatattt ctacccgaag catcggctgc
    17641 aatcatatag atacaactgc tgctaagaga atgggcatca ctgtcgacaa tgtggcgtac
    17701 tcgccggata gcgttgccga ttatactatg atgctaattc ttatggcagt acgcaacgta
    17761 aaatcgattg tgcgctctgt ggaaaaacat gatttcaggt tggacagcga ccgtggcaag
    17821 gtactcagcg acatgacagt tggtgtggtg ggaacgggcc agataggcaa agcggttatt
    17881 gagcggctgc gaggatttgg atgtaaagtg ttggcttata gtcgcagccg aagtatagag
    17941 gtaaactatg taccgtttga tgagttgctg caaaatagcg atatcgttac gcttcatgtg
    18001 ccgctcaata cggatacgca ctatattatc agccacgaac aaatacagag aatgaagcaa
    18061 ggagcatttc ttatcaatac tgggcgcggt ccacttgtag atacctatga gttggttaaa
    18121 gcattagaaa acgggaaact gggcggtgcc gcattggatg tattggaagg agaggaagag
    18181 tttttctact ctgattgcac ccaaaaacca attgataatc aatttttact taaacttcaa
    18241 agaatgccta acgtgataat cacaccgcat acggcctatt ataccgagca agcgttgcgt
    18301 gataccgttg aaaaaaccat taaaaactgt ttggattttg aaaggagaca ggagcatgaa
    18361 tagaataaaa gttgcaatac tgtttggggg ttgctcagag gagcatgacg tatcggtaaa
    18421 atctgcaata gagatagccg ctaacattaa taaagaaaaa tacgagccgt tatacattgg
    18481 aattacgaaa tctggtgtat ggaaaatgtg cgaaaaacct tgcgcggaat gggaaaacga
    18541 caattgctat tcagctgtac tctcgccgga taaaaaaatg cacggattac ttgttaaaaa
    18601 gaaccatgaa tatgaaatca accatgttga tgtagcattt tcagctttgc atggcaagtc
    18661 aggtgaagat ggatccatac aaggtctgtt tgaattgtcc ggtatccctt ttgtaggctg
    18721 cgatattcaa agctcagcaa tttgtatgga caaatcgttg acatacatcg ttgcgaaaaa
    18781 tgctgggata gctactcccg ccttttgggt tattaataaa gatgataggc cggtggcagc
    18841 tacgtttacc tatcctgttt ttgttaagcc ggcgcgttca ggctcatcct tcggtgtgaa
    18901 aaaagtcaat agcgcggacg aattggacta cgcaattgaa tcggcaagac aatatgacag
    18961 caaaatctta attgagcagg ctgtttcggg ctgtgaggtc ggttgtgcgg tattgggaaa
    19021 cagtgccgcg ttagttgttg gcgaggtgga ccaaatcagg ctgcagtacg gaatctttcg
    19081 tattcatcag gaagtcgagc cggaaaaagg ctctgaaaac gcatttataa ccgttcccgc
    19141 agacctttca gcagaggagc gaggacggat acaggaaacg gcaaaaaaaa tatataaagc
    19201 gctcggctgt agaggtctag cccgtgtgga tatgttttta caagataacg gccgcattgt
    19261 actgaacgaa gtcaatactc tgcccggttt cacgtcatac agtcgttatc cccgtatgat
    19321 ggccgctgca ggtattgcac ttcccgaact gattgaccgc ttgatcgtat tagcgttaaa
    19381 ggggtgataa gcatggaaat aggatttact tttttagatg aaatagtaca cggtgttcgt
    19441 tgggacgcta aatatgccac ttgggataat ttcaccggaa aaccggttga cggttatgaa
    19501 gtaaatcgca ttgtagggac atacgagttg gctgaatcgc ttttgaaggc aaaagaactg
    19561 gctgctaccc aagggtacgg attgcttcta tgggacggtt accgtcctaa gcgtgctgta
    19621 aactgtttta tgcaatgggc tgcacagccg gaaaataacc tgacaaagga aagttattat
    19681 cccaatattg accgaactga gatgatttca aaaggatacg tggcttcaaa atcaagccat
    19741 agccgcggca gtgccattga tcttacgctt tatcgattag acacgggtga gcttgtacca
    19801 atggggagcc gatttgattt tatggatgaa cgctctcatc atgcggcaaa tggaatatca
    19861 tgcaatgaag cgcaaaatcg cagacgtttg cgctccatca tggaaaacag tgggtttgaa
    19921 gcatatagcc tcgaatggtg gcactatgta ttaagagacg aaccataccc caatagctat
    19981 tttgatttcc ccgttaaata aacttttaac cgttgcacgg acaaactata taagctaact
    20041 ctttcggcag gaaacccgac gtatgtaact ggttcttagg gaatttatat atagtagata
    20101 gtattgaaga tgtaaggcag agcgatattg cggtcattat ctgcgtgcgc tgcggcaaga
    20161 tagcctgata ataagactga tcgcatagag gggtggtatt tcacaccgcc cattgtcaac
    20221 aggcagttca gcctcgttaa attcagcatg ggtatcactt atgaaaattc atctacattg
    20281 gtgataatag taaatccagt agggcgaaat aattgactgt aatttacggg gcaaaacggc
    20341 acaatctcaa acgagattgt gccgtttaag gggaagattc tagaaatatt tcatacttcc
    20401 aactatatag ttaaggagga gactgaaaga gagtataaaa tattttgtgt aaatgaaaaa
    20461 atccatacaa aaaaggaagt cccttctgta gaataaagtt aacgacaacc aattcacaga
    20521 aaagaggact tccctatgaa tgattttact acagaaattg tgcaaactct agtcactaaa
    20581 ggcgatttaa atgaattatt ccgttcgcac ttagaaaaag cgataaacac actcctacgg
    20641 actgaattaa cggctttttt agattacgaa aaatatgatc gcactggttt taattcaggt
    20701 aattcgagaa acggttctta ctttcgatca atcaaaaccg aatatggtga attaacattg
    20761 gaaataccta gagatcgtaa tggtgagttt aaacaacaaa ctttaccagc ctacaaaaga
    20821 acaaacgata cattggaaac cactattatc catttattcg aaaaaggtgt tacgatgtct
    20881 gaaattgctg atttgatcga aaaaatgtac ggtcatcact atactccaca aaccatgtcc
    20941 aacatgacta aagttctgac tgaagaagta aatgccttta aatccagagc cttaaatgat
    21001 aagtatgtcg ctatttttat ggacgctact ta
//
LOCUS       DACDAF010000048        20833 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.048, whole genome shotgun sequence.
ACCESSION   DACDAF010000048 DACDAF010000000
VERSION     DACDAF010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20833)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20833)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20833
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.048"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(239..523)
                     /locus_tag="IVZ69_001652"
     CDS             complement(239..523)
                     /locus_tag="IVZ69_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183735.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(541..1431)
                     /locus_tag="IVZ69_001653"
     CDS             complement(541..1431)
                     /locus_tag="IVZ69_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HAP8183736.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1451..1669)
                     /locus_tag="IVZ69_001654"
     CDS             complement(1451..1669)
                     /locus_tag="IVZ69_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183737.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1639..3339)
                     /locus_tag="IVZ69_001655"
     CDS             complement(1639..3339)
                     /locus_tag="IVZ69_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HAP8183738.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3606..4379
                     /locus_tag="IVZ69_001656"
     CDS             3606..4379
                     /locus_tag="IVZ69_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183739.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4460..5029)
                     /gene="thiT"
                     /locus_tag="IVZ69_001657"
     CDS             complement(4460..5029)
                     /gene="thiT"
                     /locus_tag="IVZ69_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HAP8183740.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5095..5197)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5203..6174)
                     /locus_tag="IVZ69_001658"
     CDS             complement(5203..6174)
                     /locus_tag="IVZ69_001658"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HAP8183741.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6268..7641)
                     /gene="glmU"
                     /locus_tag="IVZ69_001659"
     CDS             complement(6268..7641)
                     /gene="glmU"
                     /locus_tag="IVZ69_001659"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HAP8183742.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8144..8962)
                     /gene="purR"
                     /locus_tag="IVZ69_001660"
     CDS             complement(8144..8962)
                     /gene="purR"
                     /locus_tag="IVZ69_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HAP8183743.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9129..9953)
                     /locus_tag="IVZ69_001661"
     CDS             complement(9129..9953)
                     /locus_tag="IVZ69_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HAP8183744.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9926..10606)
                     /locus_tag="IVZ69_001662"
     CDS             complement(9926..10606)
                     /locus_tag="IVZ69_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HAP8183745.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10629..11567)
                     /locus_tag="IVZ69_001663"
     CDS             complement(10629..11567)
                     /locus_tag="IVZ69_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HAP8183746.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11812..12663)
                     /locus_tag="IVZ69_001664"
     CDS             complement(11812..12663)
                     /locus_tag="IVZ69_001664"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HAP8183747.1"
                     /translation="MELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADHLFFE
                     EITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAGLGGG
                     STDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQVLPS
                     MPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMGNSLE
                     DITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGFCEEV
                     YLVRTLQ"
     gene            complement(12817..15390)
                     /gene="mprF"
                     /locus_tag="IVZ69_001665"
     CDS             complement(12817..15390)
                     /gene="mprF"
                     /locus_tag="IVZ69_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP8183748.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15531..16337
                     /gene="proC"
                     /locus_tag="IVZ69_001666"
     CDS             15531..16337
                     /gene="proC"
                     /locus_tag="IVZ69_001666"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HAP8183749.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16416..17972)
                     /gene="rny"
                     /locus_tag="IVZ69_001667"
     CDS             complement(16416..17972)
                     /gene="rny"
                     /locus_tag="IVZ69_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HAP8183750.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18383..19432)
                     /gene="recA"
                     /locus_tag="IVZ69_001668"
     CDS             complement(18383..19432)
                     /gene="recA"
                     /locus_tag="IVZ69_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HAP8183751.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19541..20782)
                     /locus_tag="IVZ69_001669"
     CDS             complement(19541..20782)
                     /locus_tag="IVZ69_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HAP8183752.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
BASE COUNT         5931 a         4514 c         3589 g         6799 t
ORIGIN      
        1 acctccagac ttcttgatag ctcaagtata tcttgaggtg catttgttag taaggtactg
       61 ttctatgggg cgcttactta ataccgagaa aatggttttt gaacatcact tattcaaaat
      121 aaaaaaagat tgtgacacga attttgtcac aacctttaaa tgtattccta gagcaaagaa
      181 gctaagcgaa gaaatccaat tctgattatt tattgtattt ctttgttcag catccttgct
      241 aaaagcccat attggacaaa gtattcacta cacccatgat ctcatctttt cgagaacgtg
      301 ctttttctgt cggatcttct acctcttctg tgtcaattcg aacaataaat ttccgattca
      361 tcgtcacgta agcaccgtcg ttgatcaaaa taaacagttc gttctcatta tagtctgcac
      421 aggcatcttt ccatacgtca aagccgtttt tttcagaagg gatatcccgt ttaaccacag
      481 tttttccact taattcgtgg aacgttacgt cataatattt cattatctct acctctttcg
      541 tcattcaata ttttgtactt gttctctgat tttttctaag atcgtcttag actggacgac
      601 ttgattttta atttcgattg catttgattt ggaaccgatc gtgttgattt cccgattcat
      661 ttcttggatc aggaaatcta attcccgacc tacaggacat tgtgcttcga taagttcatc
      721 tagtttttgt acatggatcg ccagacgatc cagttcctcg tgaatatctc cgcgttccaa
      781 caagatggct agctccgtca acaaccgttg ctcatcgact ttcgctccaa gaaattcctc
      841 cagctttttt tgatacctta tttgaaattc cttttcatag atttctacaa aactatcgag
      901 tttttttagt acttctttga attcttcagt attctttttc aacactaaag ctaaagcttg
      961 accttctttt tctcgactcg cctcaataga atcaagtgcg cttttcaatg tatctagagc
     1021 taactgtgcc aattcttcca tgctctcttc cggtttttct tctaccgtta cgaagttttc
     1081 gtccagcgcg aagcgttccg ccatccgact aattgacact tgattttgac taccgtatcg
     1141 ttgttgaatt ccgtctgtca attgagtgat aagtgaatca atcaattccc agttgatgac
     1201 gatctgtttt tcgtttttgc caatataagc tagattcaca aatacttcga ttcgaccgcg
     1261 gcttaactgc tgtttaataa gctgacgaaa atcgttttca acaaagttca ggattttagg
     1321 acttcgtatt tgaacatcta gaaaacgctg gttgacactt tttatttcaa tatctaactg
     1381 atacgctttt gtttcgcgga tggctttgcc aaaaccagtc atacttttca ttcgacaggg
     1441 tccttcctca ttacatattt tctattgctt tttgcagttg ttcaaactct tcgttcgtca
     1501 atgtcaggcc tttccccatt ttttcatggt ctggcgccca atctcgaaga tcgaattttg
     1561 gcgggcgacc attccagctg actaggttca gttctttacg ccaccccttg ttgttttctg
     1621 acaatatagc gatttcttct acgatttcat atgaaaattc ttgtgccatg gttgttcctc
     1681 cttgagataa tataaatata ggatcagtaa tgtgtcaact ggttgcttaa gcaattcatg
     1741 ctgcaaacga tccttgcgtt ttccttgtag cagataatca aaataaacag ttttcgtgcg
     1801 ctcattttgt attttttgct ggtattttcg ataccttcgc cattcttcag tacttaattg
     1861 accaatttgt gccaataaat catccggcat actttttata tcttgttggc agatcatttg
     1921 aatcatcatg tctacttgat agatttcatt gggcagtaaa aaatgttttt ttgctaaaag
     1981 ttctagcatc gccaatccgc atgtctctgg tacgaccctg ttcttatata aattacgcag
     2041 tttttgccaa aattttatgc ttttgaaaaa agataattct aactgaattt cttttgttaa
     2101 gtaagacaaa aatcctcgcc agtatgttct tgcaggttta acagaatgaa atgtatacca
     2161 gttcccatag taatagccta atcgtttttt catttccaga tagcctaatt gtaaatttaa
     2221 ttggttcctt tggctatcaa aaagcagaaa gctgcctagt gtccacaatg tttgacattt
     2281 ccaatggata aaaatgtctg gcatacgaat ttttttcgct gggcctggcc cttgcacatc
     2341 tacgacaaat gcctctgttg ctcctttgtt aatcgcaata tcaataggta ttttgttgcg
     2401 atacccaccg tctgcatatt tattttttcc gatctttcga taagccatag cgggataaaa
     2461 tgaagcagag gcgagtatcc aatctggtat ttcttctgtt tttgtctgtt ggatatcagt
     2521 cactacttcc gctagttctg gcagtttagt agacaccgta tataaacgta ttttgggatt
     2581 atgtttgagt aaggacaaat ccaaattgtc tttgaccatc ttttccaatg gagcagaaga
     2641 aaccccgcct tcaattagtg ctgttttcgt catttggcgt ctttctcgat agaagcgttc
     2701 acgaaggtct tcaactgcag ccatttctgg taacgcaagc acttgtcttg tcgacagctt
     2761 tttccataaa ttcacagctt ttttcatatc tccttgtaaa atcaatgcgc cgttcaacgc
     2821 acctaccgag gtacctgtga taatctcaaa gttgatatca tgttccttca gcgcctgcca
     2881 cacaccaatc tgataagcac cgtgcgctcc tcctccacct aaaacaagtg ctgtatgata
     2941 gaccagcttt ttatttaatt gtgtggttcc ttgatagccg tttttatgaa aaatacgcaa
     3001 ccattcttct gatagaggag attgaaataa aaaacaacag ttttctttaa taaaaaaacg
     3061 agcgcaagct tccatatacc gaaaaaattt tttccattca aaagtttcac cttcaatcaa
     3121 cagattatta aaaataacat ctcctctact tttagcaata gtaaaataga cggtatattt
     3181 tttcgatact gctttaaaag cacattgctt ttttgcagaa cgccaaaaag cgtctctact
     3241 ttcttgatga ctttgaaaaa atggaagggg ttgttttgct tgctggatag gcgaatacag
     3301 cgacattttc tgtgaaaagt aaactttttt tatctccatc gcgctctcct ttttcttcaa
     3361 gtataccagt acgtcataaa aaggtcatga gtctcgtatt cgactttgta gattccataa
     3421 gaaaacaatt cataaaacct cctttaaata aaaaaataca aaaatcacaa aaattaattg
     3481 aaaatgagag tgttttcaat gaaaacgtga ttttgtaatg gaattttaaa ataaaagaaa
     3541 caagcttttt taatgcaaat gttgtaaaat aaaagagatt aagaggaaat aagaggagga
     3601 acatgatgac tgagtcagtt tatgtacata ttgataccac aagtaatgct gttttaacaa
     3661 aagggctgac tgctactgac tttgcaaaca gtatcgtgca ttttcctcaa aacttgctct
     3721 tgcttgatcc atctgcttct gctggagaat atgaatccca tacagggctg aaagtaatcc
     3781 gtggtacaga aaatattcag cgtttctttt cctcttctcg taacaggcgt ggattcgatg
     3841 aattgaagtg gatcgacttt actgatttaa cgatgctgaa agaattgaca cctttagaaa
     3901 tttcagaatt attatatttt ggtcatatga aaacacatct tcattcgccg tttttttata
     3961 aactacagaa taattttgta tacttcgatc ttaatgatca gctgaatcgg atttattatc
     4021 gctatttaga tgaattttat aggatttttg ctagtaaatt aagttcgatc ttgtcagata
     4081 agatcaatgt aaaaaaatct tttttcaaaa aagaaacacc tgttgaaaaa atcagtgtgg
     4141 aattattgaa agaaatgcgt aatttgatgc aggaagggat cattttttct tttgatcaag
     4201 ttggtttgat cgatggtaaa tatcgtatcc caatctatgt gattgaagat tatatttgga
     4261 aattaaaagg cacccggtat cgagaagagg aaatcatcgc tactttaatc tactctgtca
     4321 ccgatcgaca ctggcaattg gtagaagatg ccgatctttc ttatctgcca ttgaagtaga
     4381 tctatttctt atcaaaaaat aaaaaggaaa caagaaacta ggacatgatt ctgtctcaag
     4441 tttcttgctt cttttttatt tacagctcct gtcgtttatc tggcacaaaa atcgaaggag
     4501 tcgtttgttg gatccctaat aaaacgatga tcgttacaat agctgtactc aacccgctgg
     4561 caccattcat tacgaaagaa aagagccaag gattcatccc ccatagtgca tacgctcccc
     4621 agaaaaccac tcctgcaata aaatgccaaa aatatctgga aagtgcgcca atcaatgcac
     4681 caaacacgat gctttttcta atttgtttcg tattatcgtc tacatagcct ttttggacat
     4741 ttgaagccat gagccctgct gcgcctgcaa aagtataggc aatcgggtac tcaatcaaca
     4801 cttgaacgac acttaaataa taaacttgtc ccaacggaaa atgtaggatg ccccaaatga
     4861 aacctgccag catccctgcc tttgtccctc ttcttaacgc aaaaagagtc aatggaatct
     4921 gccctaatga aatagaaaaa ctgctgccga tctggatcgg aatcaacgac aacaccatcg
     4981 ctaacgctgc aacaatcgtt ccttctaccc aaactctatt ttttcccata aaaaaacttc
     5041 ctcctttgaa taaaaaagtc acaaaggagg aagcagcttt cgaaaatagt caaacagctg
     5101 tttattcaca attcctacgc tcgcataacc gatacaggta cgaagggttt agaaatagat
     5161 tcaatctcag cccaattgga ctcccctttg tgagtttatt tattatttat tttttgtttc
     5221 aaacaatgga ctaactggtt tgttttcatg gatacgtttg attgcatctc ccattagtcc
     5281 gccaacactt acttcatcga ttttgtcgat tttacgatct tctggaagat agatcgagtc
     5341 tgtaacaact agacgctcga tagctgaatc ttctattctt tgtaaagcag ggccggataa
     5401 tactggatgt gtacatgaag catacacact agttgcacca gcttctttca aagcattggc
     5461 agccaatgtg atcgtacctg ctgtatcgat catatcatcg atcagtacac aagttttgcc
     5521 tttgacttgt ccaatgatat tcattacttc tgcaacattt gcttttggac ggcgtttgtc
     5581 tatgatcgca atcggagatt tcaaaaattc cgctaattta cgtgcccgtg tgacaccacc
     5641 atggtctggt gaaacaacga caacatcatc gcctttgatt cctttttcta agaaataatt
     5701 ggcaataagt ggcgcaccca tcaaatgatc gactggaata tcaaagaaac cttggatttg
     5761 aactgcatga aggtccaaag tcagcattct tgttgcacca gctttttgaa tcatgtttgc
     5821 tactaatttc gctgtgattg gttcccgtgc acgtgcttta cggtcttgac gcgcatagcc
     5881 ataataaggc atgactacgt tgattgtttt tgcacttgct cgtttcagtg cgtcaatcat
     5941 gatcagcaac tccatcaagt tatcattgac tgggctgctc gttgattgaa taacatagac
     6001 atgcgatcca cgaatacttt cttcaatgtt tacttgaatt tctccatcac taaattgagt
     6061 aacagatgat tttcctaact cgacgccgac tgctgctgca attttctctg ctaatgggcg
     6121 attggaattt aacgcaaaaa tttttaatct tgggtcaaag taatgttttg acatggggac
     6181 ctccactttc tttttcacaa ctctagaatt ctacctaata aatagtagtc atatttttta
     6241 aataaatcaa gtgattttgc aaaagtctta gtttagataa gggagttttt ttgcatatcc
     6301 ttctttattg acttgtcttg ctctcgcaat tgccagcgca tattctggaa tattgtctgt
     6361 aattgttgac ccggcagcaa tcgaactgtt tttagctacc tcgacaggtc cgatgatatt
     6421 cgtgctagaa ccaataaagc tgtggtcgcc gacagtcgta tgatgtttgt tctttccatc
     6481 atagttgacg aagacaacac cacatccgac attgatttct tctcccagcg tagcatcacc
     6541 aacataagtc aagtgaccga ctttagttcc tttgccgatt tgagcatttt tcacttccac
     6601 aaagtttccg atatggacgt tttcgccaat ttcagctttt ggtcgtaaat gtgcataagg
     6661 tcccacatct gcatgtttct tgacatggct gctttcaatg actgagtttt caatgacgac
     6721 gtgatcctca atcctactgt ctacgatttt tgaatgtgac ccgatgacac aatcagaacc
     6781 aatgactgta tttccttgga tttgtacacc tgcttcgatc aatgtgtctg gaccgatttc
     6841 tacgcctgca tcgatgtatg tcgttgctga atcgacaaag cttacgccat tgaccatatg
     6901 catctggtta attcgctttc tcatgatctc atttgcttta gctaacgcga tccgatcatt
     6961 gactcccatt gattcttcaa aatcatccgt ttgataagca gcaactgtat ggccttcttc
     7021 ttttaagatt tcgatgatat ctgttagata gtattcacct tgagcattgt ttgttccaac
     7081 tttgcttaac gcatcgaaca aagcttcgtt gtcaaaacag taagttcctg tattgatttc
     7141 ttgtacaaga gcttcttctg gtgttgcatc tttttgttcc acgatttttt ctacgatccc
     7201 aatatggtca cggatgattc gtccatatcc tgttgggttt tctgcttgtg ccgtcaagat
     7261 cgttgcactt gcattttttc cttggtgata ttcaaaaaga ttgttcagcg tttcagtagt
     7321 caataatggt gtatcgccac tgataactaa cgttgttcct ttttttcctt ccaagaaaga
     7381 agcagcttgc aaaacagcat gtcctgttcc caattgttct gcttgtaacg catatttact
     7441 gcgttctcct agttgtgctt taacttgttc tgctccgtgt ccaacgatcg taatcacttc
     7501 atctggtttc gtttcactga cccgattaat gatatgttct accataggtt taccagaaac
     7561 gggatgtaaa actttatata attttgactt catgcgggta cctttccctg ccgccaaaat
     7621 aattgcataa cgtgcgtcca actgcgtcac tcctaaatat agtttgctga tttcagttta
     7681 tcccagtata cccatttttt caacaaaaca agtgattttc ttttatccca gcgttttctg
     7741 gataaaaaaa tagatagacc ataacgggcc tatctatttg gtaaccggtg ctctcctgcc
     7801 aactcctcgg tcacaagtca cactactcat aaaacatgaa aagctgtttt ttgaaatcgt
     7861 ttcttgtgac ttagagttaa acggtaggct tacaacctct tcattaaacg tttttcaatc
     7921 agctgacctt cggtattagc tcaataaacg gcaaaatatg aggagcaatt tttccgttta
     7981 ttgagctaat actcaggaca ggacgctgat ttcacaacct ctagataaac ggtgttcaaa
     8041 agccagtttc tcggtattaa gccaaattta tgaaaaaatg tggaaagcca ttttcacaaa
     8101 atttttctta ctactcgaaa ctaagcagct ttttcacaac ctcttattct gaaaaataat
     8161 ttcctggcac aaccgtaata tttttcgttt gagtatctac atctttgaca taaagcagtg
     8221 acgtataatc atcgatggcg cgatgaccgt tgaattttga ttcggcaaat acagtgatgc
     8281 caacaagttc tgattcgaat tcttcaatca agctcttcat tccgttgact gttccgccgc
     8341 ctttcatgaa atcatccact acaaggacac gtgaaccacg tttcaaactt ctcttagaca
     8401 gttccatctt ttcaattctt tcagaagatc cagacacata gttgacactt actgttgatc
     8461 cttctgttat ttttgagtcc cggcgtacaa taacgaatgg cgcattcaga taataggaca
     8521 cagcttgggc aataggtacg ccttttgtgg ctacagtcat tacagcatcg attttttcac
     8581 caaggtattt agaagcaatg attcttccaa cttgacgcag cagttcaggt tctcctaaca
     8641 aatcagagag ataaacatat cctcctggaa gcagacggtc ttgttctgat agacgttctg
     8701 ctagagattc aatatatttt ttcgcctctt catatgaaat ttcagggatg aacaatacac
     8761 cacctgcagc acccgggatt gtttccaagg ttccataccc tcgttcttta aatgttttct
     8821 tgatgattcc caaatcttca ctgatagaag atttagcaga ttcataacgt tcggcaaagc
     8881 ttgttaagga aatcaattca tgcgggtgat tcaataaata ctgtgtcatg tcaactagac
     8941 gttcactgcg acgtactttc acctattcca actcctttta agaaatttta tcgttttaca
     9001 ttatataagt ttttcttcaa aaattcgagc attttatgaa aaaataagaa aatagttcgg
     9061 tatttattaa aataaaaaga agcctataaa aaatttttcg tttttataag gcttcttttc
     9121 tttataattt agttattttt tcttctgaag gcaaccaata ttcgtttgat gatatttaca
     9181 atcaggaaca aagcaataaa gactaatgtg attgttgctc ctggaggtgt atctagataa
     9241 aacgagctag ttagtcctga cagcatccct agaaatccta cacaaacact gatagcaatc
     9301 acgacattga agcttttgcc taatcgcata ccgattgctg cgggaagaac catgattgcg
     9361 gatatcaaaa gtgcaccggc aatcgggatc atcacagcaa tagccacacc agtaatcaca
     9421 ttgaacatca tcgacatcaa atgaacgggt agcccatcca cgtgggcggt atcttcatca
     9481 aaagtcagaa catacatcgg ccgtttgaat aaaaagaaca atataccgat ggcaacgaat
     9541 aagattccta aaaagatgac ttgctcccat gtaatggtca cgatcgaacc aaacagatag
     9601 gattggatac ttgttgctga attccctccg ctcaaattca tcaatactaa cgctagcgcc
     9661 aaaccaccag ccattaaaat ggcaatggag atttctgaat aggttcggta gatcgttcgc
     9721 agatactcca atatcacagc tgctaataca acgactagca tggtcgtaag tgtaggatta
     9781 aggttcaaaa agaatcctaa cgctacccct gctaaagaga catgagaaag cgtatcagcc
     9841 atcagcgatt gtcttctgat cactaaaaac acacctagca tcggggcgat tccggcaatg
     9901 aagatagcgg caagaaacgc tcttctcatg aattcatatg aaagcaacgc cattgagaat
     9961 cctcctttct caccagtcgg atctgtctgt ccgcatactg tttgatatct tcatgatcat
    10021 gggtgatcat tagaactgat ttcccatgga catgcgcact atgtcggaga agacgataaa
    10081 attcatttct ggattcttca tccatacctg ttgttggttc atcaagaaca aataagtcag
    10141 ggtcagtagc aaaaatacgc gctaaactga ttcgctgctt ttgtccgcca gacaattcac
    10201 ctattcgccg atttcgcata tcccacatcc ctacagcttc taaagcacgc tgtacatgtt
    10261 gatgatcttt ttcagagaga cgcttgaacc agcggcctct tggatatctt cctgaacgga
    10321 ctaattcgat caccgtacta ggaaaacctg cattgaaaga tgcaacttgt tgaggaatat
    10381 aaccgatact taattttttt ccttcttgat ttttctcagc aatctttatc attccttttg
    10441 aaggtttcag taatcctaac gatgctttca ccaaggttga cttggctgct ccattttctc
    10501 cagttaaaat gacaaattca cccgcatcta catgataaga gacatcttct agtacaggtt
    10561 catcatcata gtaaaaggtc aaatcagata tttcgatata acgcacctta caacctccat
    10621 tctaaaactt aattgatact ttcttttaaa gctttcagat ttttttccat gacagaaata
    10681 taattttcgc ctgctttgat ttgttcatta gtcaagcttt ctaaaggatt caacacttct
    10741 agcttcactc ctgtttcatt cgacaatgtc tcagctacct tcgaagaggc attttcttca
    10801 aaataaatca ctttgatgtt gtttttcttc acaaattctt ttagctcagc taagcgactt
    10861 ggtgtgggtt cctgatctgg tgaaacgccc gaaatcgcta cttgttttaa gtcgtattga
    10921 ttcgctaaat aagcaaaagc agcatgctga gtgacaaatg tgcggtttgt tgcatctttt
    10981 agctcatcgg agtatttttg atccagtgct tcaagctttt tgatataagc atcggcattc
    11041 ttcgtaaaag tttccttttt atctggatat ttttcgccta attcttcagc aatcgttctg
    11101 acttctttta tagctaatac cggatcgagc caaacatgtg gatcgtattc atgtgaatga
    11161 ccatgccctt cttctgattc ttcatgttcg tctgcttctt gcgattctaa acggtcgatt
    11221 cctttagctg cttcgatcat caaggtctgt ttgctatcca ctgaatcctt taacgaatcc
    11281 acaaaaaatt ccatgtctga actattatac acgaaaacat ctgcatcgga aatttctgct
    11341 ctttcttttg cacttggttc gaaatcatgc ggctccgttc cagcagggat caaaagtttc
    11401 acgtttcctt catcccctac gatctctttt gtaaaatcat acatcggata aaaagtcgta
    11461 acgatcgtca aatcctcttt tttgtctgct tccttgttcg tatttccaca tgctgcaaac
    11521 agtaaagcac ctatcattac cgtagctgtc aaaagatatt ttttcattta tatgctcctt
    11581 tcaatgaaca aatcggaatt ttacgattta ttaacgtgaa ctaatgtatc aaaataaaaa
    11641 aacacagtca atagaaatcc atcaatttct gatttaagca tgtatattct tgattaaatc
    11701 gtaaaatgga tgagttgctg ctcatatcta gccatttcac tacaataaaa aactgaagaa
    11761 taccatttta ggattcctca gtttttcatc acctatttta cttcttatat tttattgcag
    11821 ggttcgtact aaataaactt cctcacaaaa accttttaac ccattatata ctctctgcgc
    11881 tcttgaataa tgttgacaca aggcaaaaac ggttggtccg cttccactca tcaatgcagc
    11941 atctgctccg tacttgatca tacgctcttt gatttgatgg atgactggat gccgctttcc
    12001 cgttatatct tctaaactgt ttcccatttt tttgatcatc tgctgataat cttgctctcg
    12061 gatggcttca gcaagtccgt ggatgtcttg atgttggatg gcttgcgtat ctacttctct
    12121 aaacactgta cgtgtagaga cactcattct tggtttgacc aacacaaccc agcactgtgg
    12181 catagaaggt aatacttgga tttcttcccc tttgccaccg acaaatgccg tacttccgta
    12241 gacacagtaa ggaacatctg taccgacttc caaaccgatt tctgccagtt cttctaacga
    12301 acagcccaga ttccataatt ggttgatccc tcttagagca gctgcacagt ctgtacttcc
    12361 tccgcctaat ccagctgcta ctggaatatt cttcttaaca aagatcttga caccggtttt
    12421 gatattgtat ttatttttta gcaataaagc agcttgataa acattgttcc gttcatctac
    12481 cggtaaaaat gctttatttg tttctacaat gattttgtct tctgttattt cttcaaaaaa
    12541 tagatgatct gccaagtcta cgctcgacat caccatttcc aactcatgat acccatcttg
    12601 ccgtctatat aatacatcca gtcctaaatt tatcttggct ggcgcttttt caatcaattc
    12661 catcctctca cccattcgaa aagtctaagt cgcaagtatt ctatcatagg gaaaaataaa
    12721 agtatagctt atgtctgcct agtggttgat tttgtcatcg tttcaacagc tttcacagaa
    12781 ttttctcttc ataatccaaa caagttctag tgattcttat aattctgtga gcacttcttc
    12841 tgccaaactc ggaacatttc ctttttcttt tcctatcaga ctgagtagct gcatggtagc
    12901 aaatccgaaa ttacttcctt tcctataagc aaaataacgt ccttcccaat gatcgacata
    12961 ttttaatttc ttttcataag cagactggaa ggaatagaaa aaattaccat aattatatac
    13021 gatatgcatg actttttctt gaaagaaaga aaaatctgtt tctccaacat tagctaatgg
    13081 agctaagcct agattggctt ccgagtagcc cattttctcg tatacaataa acagattggc
    13141 taacagatag tcagctaatt cctcagattc tttaggtaag acccgcaaca aatcatatcc
    13201 cgcctgcttc ttcgtcatcg gctgagcggt gatgaagcca acgacttttt gatctttacg
    13261 gacaataccg acaccgctag ataatacata tgatttatca aatcgtccca cagagaagta
    13321 tttttctcgt gcaccttgaa gccatttttg tgaaacttca tttacagctt gatgtaattc
    13381 ttccggcagt tgatcgtacc aagtaaaatg gtatccttct ttcatcaaac gttgatattc
    13441 aagttgctga ctcagccgag acaagtcttc tgttgctaga tcaacaatcc ctgcttcacc
    13501 tactttcgtg aagtgaaaac ccaattcatg aagcatcact acgtagcttt ctgatatctt
    13561 ataaaacgca agctgatagc ctaaacaatc tgcttgtttc ataaactgat tcgttgctgc
    13621 ccgcatcatt ttaggattgc caactggatc tcctaaaaca aagcatttgt ttcctttgat
    13681 ctgataacca aaaacgactt gatcttggtc gtcttcttgg taataaaaat aactgtaacc
    13741 tgacaagcga agctgatggc ttgtagctgt gcctccgtat gtttccaata aacggtcaaa
    13801 acggtctttt tcgtactcac tgccaagctt cgtagtatct tcagctaaat attgataaag
    13861 cgccactaaa gctagcaatg agatgcccaa accaataagc cctgagaacc acacatcatc
    13921 tgaaggaaac aaaataaaat gatttcctgt tattcgaccg actaaaaagc gtccgctgtg
    13981 atagcctgca attgcgtaaa cgataaacaa aaagccgaac aagctagcat caaagattat
    14041 agctccccaa gaataaacga attttgttcg ataaaattct tttctggata accacacagc
    14101 taacagaatc aagacatata ccaatatcaa ctgccaagat aacgtacgtg tgattgtatt
    14161 taaaatacca aaagatagta aagcaatcgt aggcagaaat gcctttttga cttttactga
    14221 aagtgctcta gcaaggccga gtaataaaaa gccaaccaat agattcactg tctgatctaa
    14281 aaaattgaat gagaacggca ataatacttg aaatagccga ctgattgcag acagattagt
    14341 gattgttgat agaagtacca tcatgatccc cgcaaaatag acagcactta cgagcacgat
    14401 atgcgcaacc ttttggaaaa acagtcgcgg aatgttatct aaaaatcgat tgattttgac
    14461 tcctgtatgt gtgatgaaca atagaagtcc cgtcataaaa ggtagaacat aataaaacaa
    14521 ccgataatat aatagccaaa ctactgctac atcttgccga acaggcaatt gactcattcc
    14581 taagatcatc aaaacgtcaa aagtccccat tccacctggg accatcgtca gcattcctat
    14641 caatgtagca atcatgaaca taggatagat cgaaagcatc gaaatatcta ttctcatcaa
    14701 cttgccgatg atcaaaaata ccgcaagggc tcccgtccat tgtccaaagg atgccagtag
    14761 cagaccaagc aagccttttg gataaaactc gaagaacaat gtctttctct ttagataagc
    14821 aaaaaagaaa atgactggtg ctaaaaaact accgccgaaa agccagatcc aatagcttcg
    14881 aaaaatactt tctgactgaa taaaaaagac atcaataaat gtaagaaacg accatacaga
    14941 caaaccagtc agcataaata gtgcgacttt tgatacagtg gctaaaacca tttttctatt
    15001 tgtctgcttt ccataaaaac tagcccgcag acttgctcct accacaccac caaaaccggc
    15061 gagattgttg atcgtgtttg ttacccacgc agcaagaaga aactcttttc tttccatttt
    15121 tggttttcct tgtttttcta agactctgat cgtcacccaa tcatacaaca acatcggagt
    15181 gacacccagc agtccagcca gaatcatgag caggatcgtc atgcggcttt gttgtcccat
    15241 cctttgccaa atatcttgcc aactcatgcc attagcaata tttgcgactt gatttgccac
    15301 aaagactaac acggagccga aaaaaatcag ttttaaaatc agactatgtt cctttatcca
    15361 ttgcagcatc aagtatcgtt tatttttcac attttcccat tcctaacttg tatacttttg
    15421 tgtcataccc caatgttatc ttatttattt taatttttcc actttagacc tgttctttgc
    15481 ttgcgatgat agaaaaagaa agatatccta atgctaaagg agaggataac atgaaagtag
    15541 gatttatcgg cacagggaat atggcacaag ctattattga tggtttatta aaaaaaggaa
    15601 cagtctcgaa agaagaggtg ttcgtttcca gtggacattt tgaaaatgca caaaaatttg
    15661 ctgctgaaac tggcgtccat gcatgcaaaa gtaatcagga agttgcatca caatcagata
    15721 tcgttctttt agccgtgaaa ccaaaaatca ttgaaaaagt attggaagaa ctaagagaat
    15781 atagccagaa agtcttattc atttctattg cttcaggaaa atcattaaca gatttagaaa
    15841 cagcgcttga agatcctcag gcctccatcg tacgtgtgat gccgaatgtc aatgtcagcg
    15901 taggagcagg cgtttctgcg atttgcaaaa atgaagctgc cacggaggaa cagcttcagc
    15961 aagctacgat gatttttgaa gcaatcggca gcgtctatcc tttagcagaa tcagatttca
    16021 gtacattcat tggccttgct ggcagctcac ccgcattcgt ttacatgctg atcgatgcga
    16081 tgggacggac tggtgtactg aatggtttgt ccaaacagac agccactgag attgctgcaa
    16141 aagcaattat gggttcttgt caaaaattcc tttcaagtga taaaaatcca tgggaacttg
    16201 tagaccaagt ttcttctcct ggcggtacaa ctgttgcagg tgtagttgcc ttagaagaag
    16261 caggattcat cccagcaatc atcaaaggaa tcaatacgac gatcgagaaa gatcttgaga
    16321 tgttgaataa aaaataatga tagcaatgtt ttttcgtgcc ttacaaaaaa agaagagctg
    16381 tggcttttgc cgcggctctt cttttgtatt ttttattatt tagcataatc agttgcacga
    16441 gtttcccgaa taacgattac tttgatgtgt ccaggataat ccagttcttc ttcgattcgt
    16501 ttacgaatat cacgtactaa acgaacagcg tctaaatccg agatttcttc tggcttgacc
    16561 attacccgaa cttcgcgtcc agcttgaact gcgtaacttg attctacacc ggcgaagctg
    16621 ttcgaaatat tttccagact tcttaaacga cggatgtagt tttctaatga ttcacttcgc
    16681 gcaccaggtc ttgctgctga gagcgcatct gctgcagcta caaggacaga gataacagaa
    16741 gtagcttcca catctccatg atgagaagcg atcgcgttga ttactactgg gttttctttg
    16801 tacttggcag ctaattccgc accgatctca acgtgagatc cttcaatctc atggtcaagt
    16861 gctttcccaa tatcatggag caacccggca cgttttgcta attggatatc ttcgccaagc
    16921 tctgctgcta agataccagc taattttgca acctcgaccg aatgcttcaa gacgttttgt
    16981 ccataactag ttctgaatcg cagacgtccg atgatcttga ttagatctgg atgaagtgta
    17041 tgagcaccga cttcaaacgc tgcctcttcc ccgtattcgc gaatacgttc atccatttct
    17101 ttacgagatt tctcgaccat ttcttcgata cgcgctggat ggattcgtcc atcttgtatc
    17161 agtttttcca aggtcatccg tgcgatttct cttcggattg gatcgaatcc ggaaagaaca
    17221 actgcttccg gtgtatcatc gatgattaaa tcgataccag tcagcgtctc aagcgttcga
    17281 atattacgac cttctcgtcc aatgatacga cctttcattt catcattcgg aagggtaacg
    17341 actgaaacag tcgtttctga aacttgatct gctgcgcagc gttgaatcgc taatgataat
    17401 aagtttttcg ctttgcgatc tgcttcttct ttggcacgct gttcagattc ttttaccatt
    17461 agagttaact catgattcag ctcttcttca gtcgatttca tgatgacatc tcgtgcgtcc
    17521 tcttttgata aaccagcaat tttttctagt tctttttgtt gatcttcaat cattttttca
    17581 acgtcttttt ctcgctcttc aattaattgc tgttttgaac taagtgcttc ttctttactt
    17641 tcaagtgagt tctcgcgttt ttctaacgag tcatctttac gattcagcgt ttgttcgcgt
    17701 tgaatcaaac gattctcttg agattttaat tctaacttac tttctctcag ctcactttca
    17761 acttcagaac ggtatttctg attttcttcc ttagcttcta acaatgcttc tttttttaga
    17821 gtttctgctt ctttttttgc actatcgatg attccagcag ctgatgattg tgcaccagct
    17881 atttctttct cgtgacgtga ctttgcgacc ataaacccta aaccaagacc gacaattaaa
    17941 ccgatgatag cgaggagaat gttgaatacc ataaaatcca cctccatact atctttttca
    18001 tttttatcat ctatacagct tctatgataa attattctaa actcgtcaat atgcatcttc
    18061 gcatatatgt gtacaaaaaa catgcacaac tttattctaa tgtttgtacc ccgtagtgtc
    18121 aactttaaat aaacaaagaa acggctttct acttattcat taaacgatgg tttttaaaat
    18181 aaatgacact agtttcatat aggtaaacct ttaaattgag aaacttttct attaaattat
    18241 tctttgtaga tgaacagata tttttatttt atgtacccac tcgtataatt aaataactca
    18301 cgatttcttt attcaataaa aaaacggcag gtcaaggaga gtacctactc ttcagaccag
    18361 ccgtttttgt ttatcataat ttttattctt ctactaaagg caattcttct tgtccttttt
    18421 catcttctgg gacagcgact tcttcaccaa taccataagc tgctctaact agagcagaaa
    18481 cttctgccat catttcagga tgattagcca tatagatttt agcgttttcc cgtccttgac
    18541 caatccgatc ttctttataa gaataccaag caccgctttt atcaacaatg tctttttcta
    18601 ctgccatgtc tagaagttct ccttcttgtg agatccctaa accatacatg acatctactt
    18661 cagcgatttt gaaaggaggt gctactttgt tttttacgac tttgatcttt gtacggttac
    18721 caacaatatc tgtaccttgt ttcaattgtt ctgcacgacg tacttccaaa cggatcgttg
    18781 cgtagaattt caatgcgcgt cctccaggag tgatttctgg attcccaaac atcacgccta
    18841 ctttttcacg gatttggttg atgaaaatag cgattgtttt tgttttgttg atcgaaccag
    18901 agagtttacg caatgcttga gacatcaaac gtgcttgtaa cccgacatgt gagtcaccca
    18961 tttcgccgtc gatttctgct cgtggaacta aagcagcaac tgaatcgact actacgatat
    19021 ctacagcccc acttgatact aaagcatcag cgatctctag accttgttct cctgtgtcag
    19081 gctgtgaaag aagtagttca tcgatattca cacctaattt ttgtgcatat tgcggatcta
    19141 acgcatgctc agcatcaatg aaagcggccg ttccgccatt tttttgtact tctgcaatag
    19201 cgtgtagtgc aactgttgtt ttacctgaac tttcaggtcc atatacttcg atgatacgtc
    19261 cacgggggta accgccgaca cctaaagcga catctaacgc aagagagcca cttggaattg
    19321 tagagatttg ttggtcgatt ttttcgccca atttcataat agagccttta ccatagctct
    19381 tttcaatttt tttcagtgca gcatctaagg ctgctttacg atcatctgcc aatacgataa
    19441 tcctccttat atttacaaat cagagcaaca tttcattatc cttatcatat cttttttagt
    19501 gaaaaaaagc aagaaaaaac cgaacaaata ttcgcattta tcattttctt aaaagctgtt
    19561 ttctcaaaag atcaaatcct tgcataaccg cattatatct gatagcagca cgatctctgg
    19621 caaagtgata tttttccgaa accacgccgt ctttagatga aatagcgatc catactgttc
    19681 ctgcagattg accttctaac gtgtccggtc cagccactcc ggtgaaagct acactgtaat
    19741 ctgttcttgc tatctcacgt gcttgaatgg ccatctgctc cacacattct ttgctgactg
    19801 ttccatattc tgctaatagc tccggatcaa tctccagaaa accagctttt gtttggagcg
    19861 agtaggtaac gaatccgcct ggaaatactt cagatacacc agcaatgtcg cctaatgcgg
    19921 cttggaaggc gccggctgtc aaactttccg ctgctgttac agtctgcttg ttttctttca
    19981 gtagttccac tacgactttt gctagcgaat tatcatcgcc gtatccataa aaatattccc
    20041 ctactcgttc ttggattttt tcttctaatg ctaaaagagc ttgattccct gcctgaacat
    20101 catttgtttt cactgtcagt cgtaatgtca cttcatttgg tttggcatat ggtgcgatcg
    20161 ttggattgat ctgtgtctca atcagatctt ttagctcagt gaccagtcgc gattcaccaa
    20221 tcccataaaa gcgcaaaact ttagaaatta gtttttcttc agaaggaaaa cgttcctcta
    20281 gtaaaggacg tacttgttcc acaaacattg gtttcaactc attaggcgga ccgggaagaa
    20341 ggatatacgc atgtgtatct gtttgataaa aagtccctaa agcaagccct gtacgatttg
    20401 gtagaggaac cccgccttcg ataatctggg actgttgcag attgtttttg gtcatttttc
    20461 gatgggttgt ttcaaaatat gccaataatt ttttgtatcc ttccgtattt tgtatgagag
    20521 acttaccgag gtgagccgca gttgcttctt ttgtcaggtc atcttctgtc ggtcctaatc
    20581 cgccacataa gagtatgagt tcacttcttg tttcagctag agcaatcaac tcttctaaac
    20641 gctgctgatt atctcctaca actgtttgat aataaacttc gatacctaga tcagctagct
    20701 gttctgacaa gaaagtggca ttcgtattca cgacttgtcc tagtaaaagt tctgttccga
    20761 cagctattat ttctgctttc attacttccc gctcccttat atagtatacg ctgtattttt
    20821 atattttttt att
//
LOCUS       DACDAF010000049        20326 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.049, whole genome shotgun sequence.
ACCESSION   DACDAF010000049 DACDAF010000000
VERSION     DACDAF010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20326
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.049"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(51..278)
                     /locus_tag="IVZ69_001670"
     CDS             complement(51..278)
                     /locus_tag="IVZ69_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAP8183753.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(275..793)
                     /gene="msrA"
                     /locus_tag="IVZ69_001671"
     CDS             complement(275..793)
                     /gene="msrA"
                     /locus_tag="IVZ69_001671"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP8183754.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(813..1526)
                     /locus_tag="IVZ69_001672"
     CDS             complement(813..1526)
                     /locus_tag="IVZ69_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAP8183755.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(1529..2425)
                     /locus_tag="IVZ69_001673"
     CDS             complement(1529..2425)
                     /locus_tag="IVZ69_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP8183756.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(2583..3425)
                     /locus_tag="IVZ69_001674"
     CDS             complement(2583..3425)
                     /locus_tag="IVZ69_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP8183757.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            3557..4210
                     /locus_tag="IVZ69_001675"
     CDS             3557..4210
                     /locus_tag="IVZ69_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP8183758.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(4273..4800)
                     /locus_tag="IVZ69_001676"
     CDS             complement(4273..4800)
                     /locus_tag="IVZ69_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP8183759.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(4820..5767)
                     /locus_tag="IVZ69_001677"
     CDS             complement(4820..5767)
                     /locus_tag="IVZ69_001677"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP8183760.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(5779..7665)
                     /locus_tag="IVZ69_001678"
     CDS             complement(5779..7665)
                     /locus_tag="IVZ69_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP8183761.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(7825..9903)
                     /locus_tag="IVZ69_001679"
     CDS             complement(7825..9903)
                     /locus_tag="IVZ69_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP8183762.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(9916..10191)
                     /locus_tag="IVZ69_001680"
     CDS             complement(9916..10191)
                     /locus_tag="IVZ69_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183763.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(10553..11008)
                     /locus_tag="IVZ69_001681"
     CDS             complement(10553..11008)
                     /locus_tag="IVZ69_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183764.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(11162..12370)
                     /locus_tag="IVZ69_001682"
     CDS             complement(11162..12370)
                     /locus_tag="IVZ69_001682"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HAP8183765.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(12482..12814)
                     /locus_tag="IVZ69_001683"
     CDS             complement(12482..12814)
                     /locus_tag="IVZ69_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HAP8183766.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            12962..13837
                     /locus_tag="IVZ69_001684"
     CDS             12962..13837
                     /locus_tag="IVZ69_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP8183767.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(13919..14500)
                     /locus_tag="IVZ69_001685"
     CDS             complement(13919..14500)
                     /locus_tag="IVZ69_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HAP8183768.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(14506..15765)
                     /locus_tag="IVZ69_001686"
     CDS             complement(14506..15765)
                     /locus_tag="IVZ69_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HAP8183769.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(15767..16813)
                     /locus_tag="IVZ69_001687"
     CDS             complement(15767..16813)
                     /locus_tag="IVZ69_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183770.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(17048..17323)
                     /locus_tag="IVZ69_001688"
     CDS             complement(17048..17323)
                     /locus_tag="IVZ69_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008214712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HAP8183771.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(17566..18876)
                     /locus_tag="IVZ69_001689"
     CDS             complement(17566..18876)
                     /locus_tag="IVZ69_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HAP8183772.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(19058..20287)
                     /gene="rpsA"
                     /locus_tag="IVZ69_001690"
     CDS             complement(19058..20287)
                     /gene="rpsA"
                     /locus_tag="IVZ69_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HAP8183773.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGGILG
                     DALKEEVEEKATDDSEK"
BASE COUNT         5633 a         4269 c         3439 g         6985 t
ORIGIN      
        1 taggctattg gacaaaaaac ttttttgatc ataaagtaca aaactatctc ttatatgtca
       61 tgattatttt ctaaatattt ttcccatgct tcgtcaaaga tatccatgga cggcaaatag
      121 tcgacattca gttccagata attagaaatt tcttcgtagc tagagctgtg cttaggaaat
      181 tggatgtctt taccggcttc tgtagcgaaa acagataaag catcatgtgt gccaccgcct
      241 cgcagtgtca ttaaataatg aaaaaagctt cgattcaccc ttcgttcctc caattttctt
      301 cgataaaggc agcccggcgt gcatggtttc ttttaaaatt ttcaggatgc tttttataat
      361 actcttgatg gtcttcttct gctagataaa atggttgggc tggttcgatt tttgtaacga
      421 ttggctgttc gaaacgtcca ctttcagcta actgtttctt acttttttca gcaatgatcc
      481 gctgttcttc tgtcaaataa aagatcaccg ggcgataatt gtcaccgcga tcctcgaatt
      541 gtccgaaagc gtcagttgga tcagtttgct gccagtaaag ttctactaat tgttcatatg
      601 aaatcaatgt tggatcatag ataatctcca ctgcttctgt atgtccagtc gtttggcttt
      661 ttacttgttc ataagtcgga tctggtacat gccctccagt atatcctgac atcactgtat
      721 ggataccagg aagcgtgtcg aaaggctgga tcatacacca gaagcagcct cctgcaaata
      781 ttgctcgttc cattatgatt ccccctctaa tactactcat ccgatgattt tttattttct
      841 tttgtcttgc tttcagtact gctggtgcta gttttgttgg tatttgagtt gtttgaagca
      901 tcagaggtat cttttggcaa atatagacta aaccgaatgt catcatttac taagtcgatt
      961 ttatctgctt taatatacat cccgttttgc attcggaatt gatccaacct aagcatgata
     1021 gtcagatcat ctgtattgac ttcgatccaa tctggtaatt tatagtttct cttgatcata
     1081 ttcatcacat ctttgattgg caaactcaat gttccgatag aaagacttct agcttttagt
     1141 tggacatttc cgttttccat cacatacgga tcaaaatata aatagaaatc gataggaaaa
     1201 cctagtactt cgaaagtacc attgagtagt gcttcatttt ccaaataaaa tttatattca
     1261 atatcactat ctttttgata ctcactaagg aaaaagctga tgatttgatt gactttttct
     1321 ttatttgaat tgatcgttaa gacaggatct ccttgtcttt ccgtaagagc tggtatttct
     1381 gggagttctg gttcccgatt agcaaaaata cggctgccta aaaatacggt cgaaccaagt
     1441 actaccccaa gaaggataag gaaggcgaat ttccagtaat ttgttttctt tgttttgttt
     1501 gaagatacgt cagatcttgt tttcatgttt attgatcatc ctccttctct aaccattggt
     1561 tttgtgtctc gatcagctga tctctcactg catttgccat caattgataa cctaaattat
     1621 ttggatggaa atgatcttct tcatagagca cattattttt gatgccattt agattttctg
     1681 tcgtgctagt tgtttgatct gttccttctt ctgtgacacc tacttcctga ttcaatcctt
     1741 gataaagcaa atcattgatt gggataaagt agcagttcgg catttttttt gtcaccgttt
     1801 ctgttccttt gttccaattg ttaacaattg tctgcatgtc agtgatctca ggaaagttca
     1861 aataaaatgg attgtagatg cctaaaatgt aaataggtgc ggttttattg agggatcgaa
     1921 attcttccaa tagttctgtg acattttcct gatagttttt cagtggcttt ttaaaggaat
     1981 tgaccgttaa cccgaataaa ttattttgga taactttcat caaatcatta ccgccaacag
     2041 tcagtgtgat aaaatcagct gttttgatat tgtttcgaat ttcttctttt gtttttactc
     2101 gctttaagat ctggtcactt cgttcaccat ttacaccata gttttctgtt tcaaccgcgg
     2161 tcaaattata acggtctttt agatcatttg cgacaagggg aacgaatcct ccttgcttgg
     2221 tttgatctcc tactccttca gtcagcgaat ctccgatagc tatgtagtga agtttttctt
     2281 ttttatttgg atcttctctc acagtagtta ctggtttcat tagtgggcca gctttcggta
     2341 tagaagcagc taaacctgca tagatgatga tcgcaattaa taatgggaac aaaacgagga
     2401 tcaaatgtcg tttcgttaat ttcatttttt cacctcttgt attcgattgg ttctaatgtt
     2461 atcaaaaatt ttatcaaaaa ggtagtcttt atgaaaaaag aaaacaatta ttttcctaat
     2521 tttataaaga aaaagagaat aagctgcaag cctttcaggc tgagggctta tcctcttttc
     2581 gactaatcta cataatacat gattgcaaac gcgtctttac cagtatgcgt agcgataacc
     2641 ggattcgtat gcagtacagg gatatgcatg tccgggaata attcttgcaa accctctttg
     2701 aattcttgcg ccaattcttt tgcatccgca tgtgaaatac cgatttgtcg cacatttggc
     2761 aattctttca gttcattttt caaattatta aaccatttat cgaacgtttt ctttcctcgc
     2821 cccttagtta cagggattaa ttcagaatgg gcgaaattca tcaccacgcg tatgttcaaa
     2881 acactagaca gcaaaccagt tgttcggctg attcttccac cttttaccaa gttatctagt
     2941 gtggatattc cgatgtataa ttttgtattg tcttgtactt ttttgacttc ttcaaggatt
     3001 ttctctactg ttttaccttc ttttgctaat tcagctgctc gaattacctg aaaagataat
     3061 ccttggtcag tggtatcact gtcgataacc gttactttcg tttttgttag attactggct
     3121 tgtcttgctg cttctactgt tccactcaag ccttttgtca tatggatcga aatcacttca
     3181 ctgccgtctt ctcctagctc atcatacatc gagatgaatt ctccaattgg tggttggctt
     3241 gttttgggca gattttttgc tttcgccatc atttccataa atctttcgcc gtctagttgg
     3301 tcatcatcgg gatatactgt tccgtcgatc atgatggata gcggcatgac acgaatgcct
     3361 aaagcatcgc gtacattttt ttccatcgta catgaagaat ctgttacgat ttttacattt
     3421 gtcattattt tctctctctc tttctttaac aagatgcctt attcatgtta aactacatgt
     3481 aagacaattt ctatttttag tataacagac aaataatgat ttttcattaa ttacacctag
     3541 taaaggagcc gttttcatgg aaaaaacgaa atttaatcga acgtatgaaa tattaaatga
     3601 agtgtttaat gcagtcaccc atggaattgg gactggattg agtatcgcgg gactagtggt
     3661 tcttttagta aaaggtgccc acttgcattc ctccctccat attgtctctt atgctatcta
     3721 tggatcgatg atgattcttt tatttttaac gtctactttg tttcattcat tgatttttac
     3781 aaaagcaaaa aaggtgttcc aagtattcga tcatagttcg atttttcttt tgattgcagg
     3841 aagttatact cctttttgtt tgctgagtat ccgaggatgg ctaggttgga ctttatttgt
     3901 attaatctgg ttgtttgcga ttcttggcat tatatataaa gcgttgacgt tgcataaacg
     3961 ggagagagta tcaaaagtat ctacgatcat ctatattttt atggggtggc tctgtgtcgt
     4021 ggctgctgtt cctctttatc actctcttgg aatgactggt gttattttga tggtagcagg
     4081 cgggctttct tacacgatag gcgcattctt ttatagcttg aattctatcc gctatatgca
     4141 tgttgtttgg catttgtttg ttatgttagg tgcaggtttt atgtacttct ctgttttatt
     4201 ctttacttaa taaaaaaaat aaagctatgg atgggacagc tctaaataac agctagtcta
     4261 tccatagctt ttttatatcg tcaattcgcc tgtcccgctt tttacaggat tctcattacg
     4321 ctgatacgtt tcaaattgat gcggataacg atttttttca tccatttctc cttgactagt
     4381 attgatcagt gaccaatcag accagtcaac aggtggaaaa taagcatctc catcgaatac
     4441 atgatggatg actgtacggt ataatatcgt acaaaatggc agaaattctt gataaacagc
     4501 tgaccctcca gcgatgaaaa agataccgtc tgtttctttt tccagagcaa gcacgtcttc
     4561 cacactatgc atgacatgca cgccttctgc tttataggaa gaatctctcg tcaaaacaat
     4621 cgtctgacga ttcggcaacg gacggctacc catcccttcg aatgtttttc gtcccatcac
     4681 tagtgtattt gcttctgtca tttgtttgaa gaatttcaga tcatttggca aacgccaagg
     4741 aagacggtct tcttttccaa tcaatccgtt ttcatcctgt gcccaaattg cagctaacat
     4801 tttctcatcc tttctgattc taaacagcga taggagcttt gatcgccgga tgtgggtcat
     4861 atccttctaa ttggatatct tccatctcaa aatcaaatac tgactgcttt tcctgattca
     4921 aaactaaagt cggaaatgcg cgtatttctc ggctcaattg ttctttcatt tgttcgatat
     4981 gattgatata aagatgagca tctcctaatg tgtgaacaaa ttcgccaacc gctaaacctg
     5041 tttcatgtgc aattaggtga gtcagcaacg cataacttgc aatgttgaac ggaacgccta
     5101 gaaacacatc cccactgcgt tgatacaatt ggcagcttag ccgtccctct tgaacataaa
     5161 attgaaacat cgtatgacaa ggaggcaaag ccatgctagg aacatcttcc ggattccatg
     5221 cagaaacgat caatcttcta gaatcaggag tctttttgat tgcttcgatc acttgtttga
     5281 tttgatcgat aaagccaccg tcttttgttt cccagtgacg ccattgatag ccgtagatgt
     5341 gtccaagatc gccgtatgtt tcagcaaagg aatcatcggt taggatcttc tcgcaaaaaa
     5401 gcttgctctg ctttttatat tcttcattga attcaggatc tgtcaaacat ctatggccaa
     5461 aatcagtcat atctggtcca ttatagtctg gacttttgat gtagcgttca aatgcccatt
     5521 catcccaaat atggttttta ttttgtaata gatagcggat attcgtatct ccttttaaaa
     5581 accaaagcaa ttcgcttttg atcaatccaa aaggtactcg tttcgttgtt aacaaaggaa
     5641 accctttttg cagatcaaac cgcatttggt atccgaataa gcttaatgtg cctgtgcctg
     5701 ttctgtcttc tttacgatgc ccttcttcca acaattttct tcctaagtca agatacgctt
     5761 gttccatcct ttttcctcct aatcttctac ccattcactc aagtattccc accgtgccat
     5821 tttttcttca agttgtgctt ctgtttcaga tacgtcgttt tgcaattctt gtaatcgagt
     5881 gaaattatct ccttgatgat tcatctcttc ttggagcaat gagatttttt cttcaagttc
     5941 tgcaatctca tcttcaatcg tttcccattc tttttgttcc atgtaagata atttcttctt
     6001 ttcagcaggt tccttgctct gtatttttgg tttcgctttt tcagcaggct gctgggtctc
     6061 tttttgcttc agtaaataac tggacatgtt tccgtaataa agttcttgtt ttccgtttcc
     6121 ttggaatact aataacttat ctgctacctt gtccaagaaa taacggtcat gggaaacagt
     6181 gatcacagca cctggaaaac ttctaaaata atcttccaaa atcgtcaatg ttgctatgtc
     6241 caaatcattg gtcggttcat ccaataataa aacattaggt tgctgaatca gcagtttcaa
     6301 caaaaataac cggcgttttt ctccgcctga aagtttgcct atcagtgtcc catgcataaa
     6361 tcttggaaat aaaaatcgtt caagtaattc tgctactccg atttgactgc catctgctgt
     6421 ttttgcttct tcagcagctt cttgtaagta agcaatcatc cgtttatctg gtgccatttc
     6481 ttcattttct tgtgtataat acgcaagatg aaccgtttca ccgatagaca ttgtaccgct
     6541 atccagggga attctgccag ctagaatatt aagcaatgtc gattttcccg caccattttt
     6601 accagtaata cctagtcttt cccgagattg aatcaataaa tctaaatgtt ctagcagtgt
     6661 ttggtcattt atacggtaac tgccatcttt gatttccagt acttttttcc ctaaacgttg
     6721 tgtcgctagg ttcagctcta aatcatcttc ttggtttact tggtacaagt tctcctttag
     6781 atcttcgaaa cggttgatcc gtgcttgctg cttggtgcca cgtgcctgta cgccagccct
     6841 catccaagct aattcctgtt tataaagccg cttgcgcttt tcttcttgtt ctacttctac
     6901 acgatcacgt tctgcttttt ctaagacgta agcttcataa tttcctttat actcgtataa
     6961 ttttccaaat gaaagttcga agattcggtt tgctactcta tctagaaaat aacgatcgtg
     7021 ggtaaccatc aatagtgcgc cacggtattg tttcaaatag ttttccaacc actcgatcgc
     7081 ttcataatct aaatggtttg ttggttcgtc tagtaatagt aaatcgggtt catcaatcaa
     7141 cacttgcgcc agactaactc gttttttctg accacctgat aaagtactga tttttttatc
     7201 taattcactg attcctaatt tttgcaaaat aatctttgcg ttggtatctg tagtccaagc
     7261 atcttcttta ttcatttgtt cttctgcttt agcataacgt ttttgcacat cagggtcttc
     7321 tccgttttcc cctagttcga tcaatgcttc ctcatatgct cgaacagttt ggatcaaggg
     7381 gctgtttcct tgaaagactg cttggagaac agttaattca tcggaaaatt cagctgcttg
     7441 agaaagataa ccaatacggt aatcagttgg ataaaacact gtttgccgat caccgtcgct
     7501 gctatcgata ccggcaataa tatttaagag acttgtttta cccgtcccgt tcgtcccaat
     7561 caacccgata cggtcttttt cgtggaccaa aaaagaaatc tggtcaaaca aatctttttc
     7621 accataagtt tttttgaggt cagttacttt taattctttc aacatgttcc ctccttatct
     7681 tggatattgt atcataaaaa tagtgaactt caggaaaatt tttttggtat ttgttctttt
     7741 tgtgttctca aaaaaagaac aggaccgatt cgatcctgtt ctgatatgtt ttgtttttta
     7801 taaaacttga aaatttttac ctttttattt tattggactc gttttttttg actttgctcg
     7861 aaacgcaaat cggaaagaaa agttatcaga tggtttgttc atcgtataag attctaacaa
     7921 attgatattc ctgcgatagc tgttcgcaga aaacgtcgtg attttttcag caacttcgta
     7981 ttcatcaatg atttttcttt caagataata acctcttagc atttttttcg taaacagact
     8041 atcttgctgg atcatccacg aagaaatcaa attccccgag ttcattttta ttccttcaag
     8101 tttgcgttgc tggataaaaa attgaaccat cgtttcatca taaatatcag tcaagttatc
     8161 taaactttca ataatcaact gagtattttt ttgatatgtc tctctgattt cttggatatc
     8221 ttcatcacta ataaatgtct gacgatcagc atatcttctt tgccaaaaca ttttcggatg
     8281 gagaacgatt cgcattaacc tacggacaac aatgaaccaa aagccgataa aagacaaaat
     8341 ctggcttgtg atagaatgtt cgaatcgaga aagaaaacgg gagtaaaaac gataaccatt
     8401 agaagaaagc ttgcccgaac gataactttc atccaatcca tcccgttcga tcgacaaaat
     8461 cagtgcttgt atttcttgta cttcttgctt ttcatcatcg gttaaatctt ccaagtacag
     8521 atcacgtatc cgttcttgat aattttctat cactgcttca gtggctaaaa attcttttgt
     8581 attacgatca atttccttta tttcttttcg caaaacttca acgacctctt ctaaaatcat
     8641 caaagcattc aaatccgtgc ttttcgcttc ctctgtttcc gtcagcatag gcaagacaat
     8701 gatccctatg accaaagtca ctaagatgac acccgccgtc agaaacaaaa gcaaagaccg
     8761 ctggtaaaac atcatattat tgattgaaaa tggcaaaata aaaatcgtag ccaaactgac
     8821 tgttcccttt acaccgccaa atgttaagat caagatctcg ttcaactgtt ttttgaactt
     8881 tttactgcca tctttgaata cataaaaaag actgatagaa atgaatctga tcacaaaaag
     8941 catgacagag attaatacga taatcgctaa taaaagaccg tttggatata aaccgtctcc
     9001 ccatactggc gagaacactt gcgtcaattc gattcctaaa aatataaata ctaatgcatt
     9061 cagtgtaaaa gcaatagttg tccatgtact gtgggacaag ctcgacaatt ctgcatcaaa
     9121 cacagagatt ttcctaaaac cagaagcttg gagaatacct gctgccactg cagcaatgat
     9181 tccagataca tcaaatgcct ctgccaatac ataggctaga aaaggaagca aaagttcgat
     9241 cagcagatac cctgtgacat cttgtgctga tgctttttcg atcaaatgaa ttattttttg
     9301 tttgaaccag acaagcaaaa agccgatcaa agctccccca atactagaaa ctactagact
     9361 catccccgcg tttactgctg aaaaagatcc ggtgatcagc gcaccaagag caaactggaa
     9421 ggcagtaaca ccagatgcat cattcaaaag accttctcct tccaaaatat gcatcgcctt
     9481 tttagggata ttcactcgtc cagaaagaga actgactgct accgcatctg tcggacctaa
     9541 cgctgctcca aaagcaaagc aggcagcaag tgggacactt ggcaacagga atgataacgt
     9601 cgcacctacc ccgacaaggg tcaaaatgac tcctccaaat gccaagaaca aaattgtccc
     9661 gaaatttttg agaatcgaag aaatatctgc tttttctcct tctctaaata acaatggtgc
     9721 aataatcata actaagaaca attcaggttc aaaatcgatt gattgtcccc actctgtcag
     9781 acctaatacc actccaagga aaatttggat cagtggagct ggaatcattg gcaaaatgcg
     9841 gctagctatg ttcgataagg tgatcgttac tgcaaataca ataactaact cagcaaattc
     9901 catcgtccat cccctttatt ttttattttg tgtaagcatt tttaaaaatt gttctttttt
     9961 ctttaaaatt ttggtttcga ctacttcaac ctgtgtttgg ttcccctcta attcacactg
    10021 tacacgtttt gactccaaac gaagcagatc atgtttcaga cgttccaact gacgatacat
    10081 caatatattt cttttacgca acttacaaag tatttgacgg cggtcatcca tcgaaagggc
    10141 gccatagcga tcatgcaaca gttttttttg ttgttcaaaa ctctctctca ttttccagat
    10201 ctcctataca caaacttcca tcattatagc aaagttcttt ttggatgaaa aatatttcat
    10261 tgtttcatcg tttattgcta gttagaaatt tccataaatt tttcaacgcc tcattctatt
    10321 ccaaatagta tcagatatca agtaaaactt aagaaagata aaagtttctg acaaaaggat
    10381 gtttactttc ccattcctgc ctttcttgtt cttttatcac aacaaaaaaa tggggctgcg
    10441 acaaaaatct tgtcacagtc ccttattctg aataaacggt gtggaagaga cagcctatca
    10501 gtagtaataa gacacatctc tttcacagcc tcatttttgc gtaaaaatcg atttattcga
    10561 aaaattcccc gtatacatct tctacacgtt gatctggatt gatcacgata tacaagttac
    10621 ctgttttttc gctgattttt gttgattgat attgattgtc taatccttct gttcctttat
    10681 ctagatatgg gaagtacaca agatcaggtg tgccatttcg gtaaaggatt tccattcgct
    10741 cgatatcttc gtatttcaat gcgcgattaa acatgcccat ttccagtccg cctaggttga
    10801 tatcatgtgt cgcaactgcg tccccttcat ggaagatttc gattttaaat ccagcacacg
    10861 gatggatttc aacaaattca ctgccattga ttcgtccaaa acttgttgtg atttgtttga
    10921 tccaaagatc gccgatatga cggcggttga tcgtccaggt ttctccattt ctaaaataaa
    10981 attttagcgc tgtcatttct ttactcatta aaaagactcc tttatgatgt aatttattct
    11041 tgtactacct cagtttagca caaatttatg taagtggtca catcttatgt tttttcttct
    11101 aatgacgtat ctgcccactt taagtagcca acaaagctga gcagatacag tctagtgttt
    11161 tttaaatcaa tttttctttc gataaaaaat ccaaaacctg ttttttatca ttttttattc
    11221 tttgttctac gacggctttt tcagctaatt gcaaagcttc actaacccac ttaccaggtt
    11281 tttttccagt ttcttctagc aagattttac catctactgc taattcgctt aatgacttga
    11341 taggtaaacg atcataggat tctcctacgg catccatctg aggtgtttcg tcaaaataga
    11401 tcatcaattc ttctacttgc agtgcatgtt ttttgcctaa gaagtacaat tcgaatggtt
    11461 ccaaagctcc agtttctcgt tgtcgtagtc cttggacaag tgcttgaacg tctttaatca
    11521 tttggttaga acacttccac gatttcaaaa aggaacgaat ctcattttct tttagatcca
    11581 gttggctgat caataatgcc catgcttggc tctcttcttt caatgggacg gatggtaatt
    11641 cagcaaaacg taaaagtgct tcgccttctt ctttcaaacc gggacagcaa atgtagcact
    11701 ctgtttcaat aaatgcatgg attcccgcgg cccgttcatt tcccaagagc atcttgatga
    11761 attccacatt tatacgttct acagatattt tacctaatag ctcgtggttt tctttgatgg
    11821 cgtagaaggt ttcttcctct aatttgaacc ctagttgact gacaaaacgc aacccgcgca
    11881 tcattcgtaa ggcatcttca tggaaccgct catgaggatt gcctacagct cgcaagatct
    11941 gttcttctag atcttgcaga ccatcgaaca aatcgatgat ttctccatct tctttcaaag
    12001 caaacgcatt gatcgtaaaa tctcttcttt tcaaatcttc tgccaacgaa cgaacgaatt
    12061 cgacatgatc tggtctacgg tagtcctgat aagttgattc cgtccgaaat gtggtgatct
    12121 catattgttc atcattttct aataccaaca cagttccatg ttcgatccca atatctatcg
    12181 tttttggaaa aagctgtttg atttcttctg gaaatgcgct tgttgcgata tccacatcat
    12241 ggattggctg gttcagcaag atatcacgaa cacttccacc tacaaaataa gcttcatatc
    12301 ctgcattctc taattttttc agaactggaa ttgccttttg gtattccaga ggtaattgtt
    12361 ttaatttcat ttttccaacc tttcctgcgt gtttcttgtc ctgagataaa gactcagttg
    12421 catggtgact gtttgacaag tccgtttcag agtcttcaag gccaggacca cttcatcttg
    12481 tttactcgtc cttacgctca aagcgattat ggtctctttg attgaatttt tccatgtttt
    12541 tttcaaaaac ttcagttaag tcgatattca atgaattagc catgatcatc gtaacgaata
    12601 aaacatcacc aagttcttct gctaccgagt taactggttc agaagccttt ttgctttttt
    12661 ctccataagt gtggttgact tctcttgcca attcacctac ttcttcagtt aatcgagcca
    12721 tctgagctaa tggagagaaa taccccacct tgaattgctg gatatattca tccacttcct
    12781 gctgcatact gtataaagaa cgctttttat ccatcttttt ccctccaaaa ctatcttacc
    12841 aaaactttaa cgcaaatcct agataagagc aattgagaaa atcgaatttc catgctacat
    12901 ttaggaagga atttctaaat ggaaattctg tgaaaataca taattgaaag ctggaattca
    12961 tatggtcaaa cgaaaaacag taaaagaagt tctttttatc attataggaa caagtattta
    13021 tgcatttggt cttgtttact tgaacatcgc taatcattta gcagaagggg gagtctcagg
    13081 gatcaccttg atcttaagag ctttatttgg tattgatcca gcttatacga ctttattaat
    13141 caacatccca ttgattttac taggaggaaa gatcctcggt aaacgttcct tggcctatac
    13201 tgttctaggt acactttctt tgtcattctt tttatggatc tggcaaaggg ttccactaga
    13261 aatcaattta cagcatgatc tactgatcgt ttctctactt gcgggtttag ttgcaggtgt
    13321 aggaagcggg atcgtctacc gcatgggtgg aacaacaggc ggcagtgata ttatcgctcg
    13381 gattttagaa caaaattacg gcatcactat ggggcgttcc ctattggcat ttgatatcat
    13441 cgtcttactt gcttcattaa cctatatcga cttgaaacgt atgatgtata cgttgattgt
    13501 ttcgtatgtt ttcagtcgtg tgattgattc gatcttagat ggcggatatt ctgcaaaagg
    13561 tctacttgtc gtctccaaca aaagcgaaga gattgcacca ctactgatga ccggtctgca
    13621 aagaggtgtg actttccttt ctggagaagg cgcattctct ggtaattcaa aaaaaatcat
    13681 ctatatggtc gttagctcta gtgaattaac tgaagctaag aggatcgtcc acgagattga
    13741 cgaaaaagct ttcctttcaa tcatcaatgt gcatgaagtg gaagggcaag gctttactta
    13801 tttgaagcca cagacaagat tactgaaaaa actataagaa aaaagacaaa gataggctat
    13861 gaggaaagat tccacatcca gctgaccttt gtctttttta gtactatact atttttaact
    13921 aattgttatg ttcacttacc cggttacttt tcttttgtgt ctgcaaaagg atctttcggt
    13981 taacttcatc agataatttc aaaaaagcat ccctatctcc atcttctagt gcttgatcga
    14041 tttgagcata aagcattttt agttttgcct cttcttcttt ttcttgaaaa tatcgttcaa
    14101 ttaattcagt atcttcttca ctgactgaag aatcccaaga agaaaatgga ttgtcttcta
    14161 agatagatag atattctctt gtctgccaag cattttcgaa tatacattcc acatataaag
    14221 gctttttcca attcaaacgg atttcatgaa aaatctggtc tgtgtccgta aattcttttc
    14281 cctgcaaaaa caatttcatg ggttcccctt caacagatag atcactgatc tgcagtcctc
    14341 gatccgcaaa attcgcccct tcaacaaagt ggacattgct taaaatcgct tcatgattgg
    14401 caagataatt caagatccaa aaaacttctc ttcggctaaa agatacatga ttgaccatcc
    14461 acgttaaaaa attcttcttt tcccgtacat caattagcat ttttctcacc tctctgttag
    14521 gtcatctaat aatgacagtg cctccatatc tcctggttca agtgttaaat aataagtcaa
    14581 taattcttgc gctcttttca gctgcccttc ttctcttaag aaaaaggcat actctttcaa
    14641 gaaatctggt tcatgtgata gttcatgata agcctgttca tagtgtacag ctgcaacggt
    14701 aaagtcttct aattcattat aagcatgggc taggttccat tctgcataag gattagcagt
    14761 ttcttccatc tgattgatca cttgtatcac atcttcatat ctttcatcat ccaagtaaag
    14821 attacttaaa gtaagtaatg tttcatcttg tttgtctcct acttctaaag ctttcagtaa
    14881 aagttcttct gctcgctgtc tatcatgcag acggaaagca ttttccgagg ccaggtgata
    14941 aagttcgact tggtaaggat tttctttgat tccttcttct aacactgttt gtgcttcttc
    15001 aatcatttct tcttcttgaa gagcttgtcc tagatataga tataacgatt gataatgcgg
    15061 attaacttct cgaagttctt ccagatagtt gattgcctgc tgattttctt tcaattgaag
    15121 attcgtaaaa gctagctgga acagtcgatc atctgtcctt tcttctttca gtgcttcttc
    15181 taaaggtacg atagctgctt cgaattctcc ttgcatactt aaggattgtc ctaaacgttc
    15241 ctgcatcgag attcctgaaa tttcatttat cccgcttgcc aacaatgttt cataaaccac
    15301 tgctgcctct ttgaaacgat caactgaaaa atacaattca gctagcgcaa actggatcaa
    15361 tggttcatca ggaagcaacc cagctgcttc tttcaatttt gcttcactca cttcagggat
    15421 tccgataact tggtacaaat cagctatcgc caataagctt tgcggatagt aatcactttg
    15481 cttatccact ttttccaggt attcaaaagc taagtcgatc tcattatctt cgattgcaat
    15541 ttctgctaac gggatgttca gtccgtcatt ttctgggtat tggttgatca gttgttcaaa
    15601 aatctgtttt gcttcgatca aaaagccaat agccagcaat tcttcgccta gttcagctaa
    15661 tatatctgct gggtcttctt ttaatgcttt ttctaaaaag atttgtgctt gtgacaagtc
    15721 ttcatctgat aaagcttgca acattttttc gctatttgta ttcatttcaa ttccctctta
    15781 tctcactgac gatttgttga aataccgtca ttgttctcaa taattctttt tcgtttggat
    15841 gttggtatcc gtctattata cctatttttt ctaaaacaag tatttttttg cttttttctg
    15901 ccaaaaaaag aactttttcc aaatactcca tctttgaaat ctgttccagc cagtggattg
    15961 gatagccaag caagtccagc cacacaaaaa agttttttag ttggaaatca aaaggatatg
    16021 cttggagatt ccacacgaaa tgaaacatca ttcctaaaaa ttttttcata ctagcagaaa
    16081 gtagatggcc attttcggtc agataaaaag cttgttcaaa cagtttacca taatttgaca
    16141 ggttttctgc ctctaattga taaaaataga tcatttcttc gatcatcccg gcaaacggcc
    16201 gagtcgttaa ttgcttttta tttggatagt ttttatacag attttgcaaa aaacgatgat
    16261 cacaaatcat tccgcaacag ataaaagtca aaaagtcaat ctgctttccg tccacctgcc
    16321 gctcgctgat tgtttgatca taaacgatgc gttctggcag attgatggtt tgcagcacta
    16381 cacgatttgg tagctgcaaa atcgtccgct gcggtgttaa tgctcggctt agagaacgga
    16441 tcgatacagg gatcatccat agtgatgaat caagggttgt atgtttttga aaaaaacctg
    16501 ccagatccat gatcccttca tttccaaatc cgatgataaa catggattga ttttcgggat
    16561 agcgtttgac gaaatcaagc aggttcttta attctgttaa atgattgcat tgagtgttgg
    16621 cacaaatata ccagtcattg tttgcttgat ttgcaaataa cgggttgatc ttatctgcaa
    16681 acaaatcata atagcgctga ttcgttaaaa ataagattgg ctgatcaatg gaaagttctc
    16741 ttagctgact gactagcgtt tctccgtaaa acactttcgt caacgcatct tctacttgat
    16801 aatcaagttc catacgcatc cctcctcttc ttatttttat tttaccatta gtaagcaaat
    16861 tctagaaaag ataagagcaa agctcacctc ataacttgca aataaataaa aattaaataa
    16921 aatacatgtg ttttctatgt atgacatacg gattcggaat ctctgtctct tatttattcc
    16981 ttttctgcta ggaaataaaa agaaaagcac ttgtagccct agagccacaa gcgctttttc
    17041 aactgtctta tttaacagcg tcttttaatg ctttacctgg tttgaatgca ggtactttgc
    17101 tagctggaat ttcgatttct tcaccagttt gtgggttacg acctttgcga gctgcgcgtt
    17161 cgcgaacttc aaagttacca aaaccgatta attgaacttt ttcgccgtta gctaaagcat
    17221 cttgaatagt tgaaaataca gcatctactg ctgcagttgc atctttttta gttaaatcag
    17281 tagctgaagc aactttttcg attaattctg ctttgtttgc catggataga ttcacctcct
    17341 ccacaagaga tatgatagaa atatcattta gttaaaactt tctgagtggt ccagaagttt
    17401 aaaaagaaat attgattaac ttcaatattc tgttatcacg atatcatatg aaccgcttaa
    17461 tagcaaggtt tttaccaatt ttcacatgct ttttttagtc atagaaacgt aacaaacgaa
    17521 actgtctttt tcttttgaaa aaaaaacgtc gatatggtaa aatgcctatt ttctcctacg
    17581 agggataatt cggatggacg tcccttcaaa agtaaatgct tttctgattt gattttctaa
    17641 gaaacgttca taagaaaaat gcatcaattc ctcttcattg acaaaaacga caaatgtagg
    17701 tggtttgaca gcgacttgtg tagcataaaa aatcttcagg cgttttcctt tatctgttgg
    17761 tgttggattg attgctacag catccataat gatatcattc aacacagccg aagagatacg
    17821 aagattctgg ttcatactta cttgttcgat catttcaggc agacgttcca accgttgttt
    17881 agtcactgca gaaacaaaaa cgattggagc gtaatcaaga taccggaatt catcacgaat
    17941 ctcttgttcg aaatcacgca ttgtattggt ttctttcttt acaagatccc atttattcac
    18001 gacgataata attccacgac cagcttcatg ggcgtaaccc gctactcgct tgtcttgttc
    18061 ccgaatccct tcttcagcat tcagtaccat caaaacgata tcagaacggt caatggcacg
    18121 cattgcacgc atcacgctgt atttttcagt attttcgtat acttttccgc gtttacgcat
    18181 accagctgta tctatcatta agaatttctg accactttca gaaacgaagt gggtgtcgat
    18241 tgcgtctcgg gtcgttcctt caatatccga aacaattaca cgttcttctc ctaaaatcgc
    18301 attgatcaaa gaggatttac caacatttgg gcgaccaatc aaactaaact taatcgtgtc
    18361 gtcgtcctct tcttcagtct cttcagagaa atacttcact gcttcatcta aaatatcacc
    18421 aatccctagt ccatggcttc ctgaaacagg ataaggatcg cctagcccta aggaataaaa
    18481 ttcatagata tcgtttctca tttctggatt atctacttta ttgactgcta aaatcactgg
    18541 tttattactt ctgtataaaa ttttcgcaac catctcatct gcgtctgtca cgccttcgcg
    18601 tccgctgact acacaaatga ttacatctgc ttcttcaatc gcgatttctg cttgatgctt
    18661 gatctgatcc ataaaaggtt catcgccaag atcaattccg cctgtgtcga tcacgctgaa
    18721 ttctcgacct aaccattcac cttttgcata aatacgatca cgagttactc caggagtatc
    18781 ttcgacaatc gagatacgct caccagcgat gcggttaaaa atcgtagact taccgacgtt
    18841 cgggcggcca acgattgcaa ttgttggatt tgccatatta tttcctcctc acaagtttcc
    18901 aatctcactt agtttaacga atgcattgcc aactttcaag catagattgt caattaaacg
    18961 aagtattttt attccttatt gaaatactaa tcgcttttca aaagaaaaac tgagacaaaa
    19021 gcagctgctt tcatctcagt cacagataca aaatcaatta tttttcagaa tcatcggttg
    19081 ctttttcttc tacttcttct ttcaacgcat cacctaaaat gcctcccata gtaaatccag
    19141 tattttcttc tggtaattca taagactcaa cattttttgg ttcttcttct gaagctggtt
    19201 tttcttctaa agctttgata ctcaatgcaa tacgatgttc ttctggatgg atctctaata
    19261 ctttcacttt cacttcgtca ccttcatgaa gcacttcatg tggtgtcgca atatgtttat
    19321 gtgaaatttg agagatatgg actagccctt ctactccagg gaacacttca acaaaggcac
    19381 cgaagcttgt caaacgttta actgttccgt ctaatactgt gccaactgga gcttttgtat
    19441 cgatttctga ccaaggtcca ggctgtgtgt ctttgattga caaggaaaca cgttcttgtt
    19501 caggattgat agacaacact ttgacattta catcatcatt gacagccaat acatcacttg
    19561 gttttgctac atgactatgt gaaatctctg agacatggac tagaccgtca attccgccta
    19621 ggtcgacaaa tgcgccaaaa tcagtaagac gtgcaacacg tccactgaga acatctccct
    19681 catggatagt tgaaagaatt tcttttttct tttcttctct ttcgttttcc actaccgctt
    19741 tatgcgataa gatcaaacga ttttctgatg gttcgatttc gatgatttta aagctcaatg
    19801 ttttgccttt atagtctgaa aagtctgcaa caaaatgatc ttccaccatt gatgcaggga
    19861 caaaaccacg tacaccgacg tcaacgacta aaccgccttt gacaacattt gtaacaggtg
    19921 cttcgatgac cttgccctct tggaaatctc tttcgatatc ttcccaaact tttttagcat
    19981 ctaaacggcg ttttgaaagt agatagctgc cgttttcttt atctttgccg atcgtactga
    20041 taacgactaa atctaataca tcaccgactt ttactacttc gctgatatct tctaccggca
    20101 aagttgataa ttcttttgcc ggaacgactc cttcaactcc agccccttcg attccgacaa
    20161 tcacttgttt gtcttcaatg actaaaactt cgcccttaac aacatcgcca acttttactt
    20221 cttgtacgct tttcattgcg tcttccattg actggttgtt ctcttgattt tgatcaaatt
    20281 ctgtcataac acttgtcctc ctaaccaaca ttctgccgta agtacg
//
LOCUS       DACDAF010000050        20262 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.050, whole genome shotgun sequence.
ACCESSION   DACDAF010000050 DACDAF010000000
VERSION     DACDAF010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20262
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.050"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            208..2250
                     /locus_tag="IVZ69_001691"
     CDS             208..2250
                     /locus_tag="IVZ69_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP8183774.1"
                     /translation="MNKRIREILKLIIKNPEMKLSTLTSELDLTRRQINYAINQFNEE
                     LKTKNIPLIQRSHSGNITVPIEVIQMISQPDYDIGDDQELVVLTDSERQALIVMTLIA
                     NIDYISLDHLVDAVDVSKTTVMEDIKRTEPFIRNYSLTIRYNRMNGYQLVGSEHRILQ
                     LLSDLVKRFPIFRREMIRRKLAQDVSEEEIVHLIHNMEQMLHLSYSDESVDYLQTSAR
                     FLVSRGIKMSDKHAFFPDDVTDTPEFRMLMILVHETGWSLSKSYMEWFTLLFLTSNIF
                     ESKTTQNYDSDQELRKLISQMVENFQNQTLILIDDREDFERRILSHLRPACFRIRYNL
                     SLGVYSIDSLIKDSNHAILIDLMKELIIPIENWLNKAFPNDELDLLSYYFGYQLSNHN
                     KLNKQRQRAVVVCTNGVMVSKLVRANMEKLFPEIHFLASLSVRDFYKFEADYDLVFTT
                     TPLKSSMLQFMIEPIMTYQQQISLRYRVLSDLGITKVDRAMDELLTIIRKYANITNPV
                     SLREELQYFLIKEDGSTPLDNFNVLPSLTYYLRPSYVQIVEEEMSWERAVEVACRPLL
                     EHQIIDSRFIADCLDQIRQPGYAGYLGMKTCIPHTTVDKGVISDGVSILVCKKPIRFP
                     NGEDVSLILPLSFFDLTKHLRAINQIADIAKDDSLIEQLLIADDEKTVYQLLRQRS"
     gene            2261..2881
                     /locus_tag="IVZ69_001692"
     CDS             2261..2881
                     /locus_tag="IVZ69_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HAP8183775.1"
                     /translation="MRLADYPKLTVIMRGYTFDQADAILQAMQEFDHQFAVEMTMNTK
                     GALENIHELNQRYGDTTYIGAGTVRTLEQAQACYEAGAKFLLGPHMFTKEMLSYANKK
                     GLLAVPAAMTPSEVDRMFKEGADIVKVFPAAVVTPRFFKDIQAPLGKLPLMGVGGISK
                     ENAKEFFEQGASYLGLGSGMFNKQDIEELNVKNLARSMKELIEAIK"
     gene            2893..3351
                     /locus_tag="IVZ69_001693"
     CDS             2893..3351
                     /locus_tag="IVZ69_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP8183776.1"
                     /translation="MELYLNEELVFRNVQAKTDSEVLAFLASEMYKKNYVKEEYIQAI
                     QEREKEYPTGLPSTPPGIAIPHANYEMVNKTTLAIATLKDPVLFHNMEDNNEQLPIQI
                     VIMMAIGEPHGQVEMLQKIVGIIQDEPLRQEMIRAGNDTELLELLKKAVF"
     gene            3370..3648
                     /locus_tag="IVZ69_001694"
     CDS             3370..3648
                     /locus_tag="IVZ69_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8183777.1"
                     /translation="MKRILVACGNGIATSTVVATKVREYLQQHGIDVSTTQTKLMEVP
                     GKVQDYDLLVTTGQFDGQTGGVPVIKGMPILTGIGADQTMEEILNLLK"
     gene            3673..5040
                     /locus_tag="IVZ69_001695"
     CDS             3673..5040
                     /locus_tag="IVZ69_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002386123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAP8183778.1"
                     /translation="MKIIMNVFNFFIDAGPTVMLPVIITIIGLIFGLKISRAFKSGLT
                     LGIGFAGIKLILDFMTTNVGPAAKAMVDRTGVKLDALDVGWGSIAAVTWASPIIPILI
                     FAILLVNIVLLILKRTHTLDVDIWNYHHMAIVGVIVYFVTKNVFLGVGASVVMAIATF
                     KISDWSQPMVESFFGIPGVSLPTVSALSSLVIAWPLNWLLDRIPLFRKSKFTIKDAQK
                     YLGFFGDSMIMGLVIGMVIGVLAGYDIKAVLQLGVSMSAVLVLIPKMTSLFMEGLMPI
                     SDAAQKWSQKKFKGTRLFIGLDAAVVVGNPDVITTALIIIPLTIALALVLPGNRVLPF
                     ADLAVVPFRVAMVVALTRGNLLKNIIIGLVVTASLLWCGSATAPMLTAIAKSVGINLG
                     TSSMLISSFAATSMIQSYLVFIAFAYKPIIGIPVLLLAFAGAWYYFDGIKKVNHEMDE
                     PLKAQ"
     gene            5055..6200
                     /gene="dgoD"
                     /locus_tag="IVZ69_001696"
     CDS             5055..6200
                     /gene="dgoD"
                     /locus_tag="IVZ69_001696"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HAP8183779.1"
                     /translation="MKISDVTVYKVKPRWIFVKISTDEGIEGWGEMISGTKTETVVAG
                     AYEIGNRLIGRNPFEIERLFQEMHRSFFRGGPINGTIVSGLEMALWDIKGKAFNVPVY
                     ELLGGAARDKIKVYSWIGGDRPSEVAEQAQDRFDRGFTAVKMNATEELHYIDSYQKVD
                     EVVERVASIRERFGDAMDIGVDFHGRVHKPMAKVLAKALEPFHPMFLEEVVLPENEEH
                     FKEVADSVAVPLATGERLYTRWQFKNLFKQGTVDIIQPDVALCGGILETRKIAAMAEA
                     YDMAVAPHAPYGPVALAATLQVDSCTPNVFIQEQSLGIHYNKGFDLLDFVKNKEVFQY
                     KDGYVDLPSKPGLGLEMDEDKIKEIAQEGLIWTNPQWKNYDGTIAEW"
     gene            6227..6718
                     /locus_tag="IVZ69_001697"
     CDS             6227..6718
                     /locus_tag="IVZ69_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183780.1"
                     /translation="MAEALMITVFLGLLIILQIIDQKKIIVFAQSSPVRKSLSILLTV
                     AILLIFWPEHLTDQIKLVAFASVILINGFLKEGLAKDSVVRFGVLNGNFNRYPQVQVE
                     KLGDDKSFISFYKSKNNSFSMIFDKDQTEMMDVFQELDIHSKITLDQSSEEKRAVVKK
                     DNE"
     gene            7161..8360
                     /locus_tag="IVZ69_001698"
     CDS             7161..8360
                     /locus_tag="IVZ69_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8183781.1"
                     /translation="MRDQTSGKMIRFYYTSLHFLYWMMFCSVYGFATLFLIYFKIDPA
                     KIGGILALVNIVSTVLQPFVSQVIIKKRKIPLITVLKTMIAGLGVILLAGVLIPNLPI
                     ITYILGGILVVSMQSFLNALAFEYSNTGYRINFGFSRAGGSFSYAVTSFLLGQLLAIY
                     SAAILPILVIVEAVIFFVILHLLPDVKNQEVFPMTKEQDRSVSLRKKYPFLILLFLGF
                     SFLFTFHTMINSFLAQIFENIHGGSKEVGIALMIAALCELPGMIFFEQLVKKKSSKFW
                     LSVASISFAVRGFMMLLASSILMMEMTHLLQAFSFALFIPASAYLFNQFLADDDRVFG
                     QTMIIIATTLGGVIGNVLGGSLLQHFGVWEMLIFGTGFAVLGALLTILGIRKIPKTGN
                     DSDSLVE"
     gene            complement(8855..9613)
                     /locus_tag="IVZ69_001699"
     CDS             complement(8855..9613)
                     /locus_tag="IVZ69_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP8183782.1"
                     /translation="MDTKLSESEKYLWDFIQSHILEIPSYSIVKLSEYANVSTATVVR
                     TMKKKGYEGFTSFKHSLKEKENTNINFAALDKVDEGIKTAILKNEQEVIRTINMVESG
                     NIEDAIQRIKAARRIMIFARGFSELIAQEMMVKFQLTGKYCEMHTDPNIIKNISRKLS
                     KDDIVIFVSLNGETKELTTAAENCYKAEIGTILLTANRHSSLMEHIEIPFVGFKSEGS
                     FFPDYEVRSRLPLSILARILLDSYALRTSGFTQH"
     gene            9781..10716
                     /gene="pfkB"
                     /locus_tag="IVZ69_001700"
     CDS             9781..10716
                     /gene="pfkB"
                     /locus_tag="IVZ69_001700"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP8183783.1"
                     /translation="MSVYTCTLNLAIDLFIETDEMKPSQVNRTNDDDIQANGKGVNVS
                     LIMKQLGIDSTALGFKAGFTGNYIEDYLHQKDISTDFISVPGMTRINVFTQVNKTNEE
                     FKLVNKGPEIPQEQIKTFLNQIQKLQADDYLCVSGSLPRGVSPEILIDISRICFENKV
                     HLIIDSSYPEIIDCLPYQPFLLKPNEEELQSWYNVELSDREGYIHYAERLIADGAKNV
                     LLSLGGEGGIFLNKDIVYSGNSPKGKVVNTACAGDTLLGTFLAGYLKGEQVDINLKKS
                     LAAGSSTAFRKGLTDFSDVAELEKQIEIKEGASKK"
     gene            10713..12158
                     /locus_tag="IVZ69_001701"
     CDS             10713..12158
                     /locus_tag="IVZ69_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8183784.1"
                     /translation="MTTYKIVAATGCPTGIAHTYMAQEALEQAAKRKGVSIKVETHGQ
                     VGIENELTPEEIKNADAVIIAADKDVQAERFAGKRVIDVPVSKGIKDADQLIEDALAG
                     KGSITAENKTVDAAGEKAEMGVAAGIGHSIYKNLMNGVSHMLPFVVAGGVIIAISFAI
                     WGVYSFDPNDPTYNPTAAMLKGVGDAAMGMMVPILAAYIAEGIAKRPGLVVGFVGGLL
                     ANSGGAGFLGGIFAGFLAGYFILLLQKVMKGLPKQLDGLKAIFLYPVIGVLFVGVVMS
                     LLANPMEAVNQGMMNFLAGFQNSNPLILGIIVGCMSAFDMGGPVNKAAYVTGTALLAQ
                     GNHTFMAGVSAACIAPPLITGFAALFFGKYFDTNDRNAGLVNFILGSTHITEGAIPFA
                     AKDPLRVLPTMMLGSSIAAVLTYMFGVQVPAPHGGFLVLPVVTGKVAWVGSILLGSIV
                     GGVILGLIQKRSVEKREAEAAAVEMKEATNN"
     gene            12186..12641
                     /locus_tag="IVZ69_001702"
     CDS             12186..12641
                     /locus_tag="IVZ69_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP8183785.1"
                     /translation="MTLIKTNKVFMNKNFTTQDEVMNFLADQSIVLSISEDRDAVYEK
                     LMEREEESTTGMMDGFAIPHAKDASIKDADIVIVRLNGKVDWKSLDGEGTDFVIALFI
                     PDSEAGTTHLKFLSQVARLLMHKDVTEGLKQAQSAEEIAELLNQKLEEN"
     gene            12660..13634
                     /gene="lacD"
                     /locus_tag="IVZ69_001703"
     CDS             12660..13634
                     /gene="lacD"
                     /locus_tag="IVZ69_001703"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAP8183786.1"
                     /translation="MPLTEKKKTYIRQLSNESGIISALAIDQRGALKKMIGKFQNKSA
                     TDEQIINFKKIISSELTPYASAILLDPEYGLPAAEVRDKNAGLLLAYEKTGYDASTPG
                     RLPDILSIWSVKRLKEQGADACKFLLYYDVDESDDINDQKKAFMERIGSECVAEDLPF
                     FLELVSYDANDPDTSSKEYALKKPHKVNEMMKEFSKPRYGVDVLKVEVPVNMNYVDGY
                     TKNEVAYTKEEAAAYFKEQSETTNLPFIFLSAGVTAELFQETLKFAKEAGSTFNGVLC
                     GRATWANGVEPFVTKGEYAAKEWMQTQGRKNIEELNNVLKETATAIKL"
     gene            complement(13745..14306)
                     /locus_tag="IVZ69_001704"
                     /pseudo
     CDS             complement(13745..14306)
                     /locus_tag="IVZ69_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364878.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
     gene            14450..15064
                     /locus_tag="IVZ69_001705"
     CDS             14450..15064
                     /locus_tag="IVZ69_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8183787.1"
                     /translation="MELAFKQLEKKDYKKAIQFAIKGMHFDWYTKNKLLLNLYGRYFW
                     YLELNRATQIIALYADDELAGVLLADIKGKSKKHHSFSQKLYVKLFDFLQNAFVKDSK
                     GGYDDTNDELLSDYLKKHSPDGEIVFLAANPDLKIKGIGSKLLKEFERREQGKEVFLF
                     TDSGCTYQFYERRGFERKKEKDNVMKILNKEVDLRCMLYSKIIQ"
     gene            15305..15688
                     /locus_tag="IVZ69_001706"
     CDS             15305..15688
                     /locus_tag="IVZ69_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8183788.1"
                     /translation="MPKYKEIALALKERIVEGKYQEGSKLPEQESLAREFKTSRVTIR
                     KAIQLLIDEGLLYTRRGSGTFIRSNIRQDNENVTQVNNVFGTSSQENTNVTSKIIRFD
                     VRFPTDYERRLSATYFRSPSCKSWV"
     gene            16051..16560
                     /locus_tag="IVZ69_001707"
     CDS             16051..16560
                     /locus_tag="IVZ69_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HAP8183789.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILEVFAEAELYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            16660..17310
                     /locus_tag="IVZ69_001708"
     CDS             16660..17310
                     /locus_tag="IVZ69_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183790.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEVRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            17761..18699
                     /locus_tag="IVZ69_001709"
     CDS             17761..18699
                     /locus_tag="IVZ69_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HAP8183791.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            18712..19764
                     /locus_tag="IVZ69_001710"
     CDS             18712..19764
                     /locus_tag="IVZ69_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8183792.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            19822..>20262
                     /locus_tag="IVZ69_001711"
     CDS             19822..>20262
                     /locus_tag="IVZ69_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HAP8183793.1"
                     /translation="MTYVFLPKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISV
                     FGDVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFVGTSKTLAILAVATVGLYGIGDCI
                     FTGLFSINTNESSWNLSTWIHNTGSGLGYAGFLLFPLLLVLLYRQ"
BASE COUNT         6419 a         3221 c         4278 g         6344 t
ORIGIN      
        1 catccaatat tctaccgaat atttaatatt cacattagcc ctaaaataat tgtcatacca
       61 tgttacattt gatataacag cgttcatttt aaaaatagct gttagtgtga caaaacatta
      121 aaccaagtgt gacaaaaaac gtgatgaaag ctttccggaa acgtatgtga acaagtatat
      181 aatgattttg tcaggaggat agtcaaaatg aataaacgaa ttcgtgaaat actcaaactg
      241 attattaaaa accctgaaat gaaactttcc actttaacaa gtgaacttga tttgacacgt
      301 cgtcaaatca attacgcgat caatcaattt aatgaagaat tgaaaacaaa gaacattccg
      361 ttaattcaga gaagtcattc tggaaatatt acggtaccaa tcgaggttat ccaaatgata
      421 tcacagcctg attacgacat aggtgatgat caggaacttg tcgttctcac tgatagtgaa
      481 agacaagcat tgatagtgat gactctgatc gctaatatcg attacatcag tctggatcat
      541 ttggtagatg cggttgatgt tagtaagacg actgttatgg aagatatcaa acgaacggaa
      601 ccgttcatca gaaattatag tctgacaatt cgatataatc ggatgaatgg ttaccaattg
      661 gttggttcgg aacaccgtat cttacagctg ttatcggatc tagtaaaacg gtttccgatt
      721 tttcgccgag aaatgattcg cagaaaattg gcacaagatg tttctgaaga agaaatcgtc
      781 catttgatcc ataacatgga acaaatgttg catcttagtt attctgatga gtcggtagac
      841 tatttgcaga catcagcgag atttttagta agccgtggga tcaagatgtc agataagcac
      901 gcgttttttc ccgatgatgt gacggatact cctgaattcc gaatgctgat gatcttggta
      961 catgaaacag gttggagtct atccaaaagt tatatggagt ggttcacgtt attattttta
     1021 acttccaata tttttgagag caaaactact caaaattatg attcggatca agaattgcga
     1081 aaattgatca gccaaatggt tgaaaatttc caaaatcaaa cgttgatttt gatcgatgac
     1141 cgagaagact ttgaacgtag gatactgagt catctgcgtc cagcctgttt tcgaatacgc
     1201 tataacttga gtttaggagt ttattcaata gatagtctga tcaaggatag taatcatgcg
     1261 attttgattg atttgatgaa agaattgatt attcctattg agaattggct aaataaggcc
     1321 tttccaaatg atgaattaga tcttttatcc tattactttg gctatcaatt aagtaatcat
     1381 aataaattga ataagcaacg acaaagggct gtagttgttt gtactaatgg tgtcatggtc
     1441 tcaaagttag tacgagccaa tatggaaaaa ctttttccag agatccattt tttagcttcc
     1501 ctatctgtgc gtgatttcta caaatttgaa gctgattatg atctggtctt tactacgacg
     1561 ccactaaaaa gttctatgct gcagtttatg atcgagccaa tcatgacata tcagcaacaa
     1621 atcagtttac gatatcgagt tttgagtgat ttaggaatta ctaaggttga tcgagcaatg
     1681 gatgaattgt taacaatcat taggaaatat gcaaatatca ccaatccagt ttcgttgcga
     1741 gaagaactgc agtacttttt gatcaaggaa gatggaagca cgccgctgga caacttcaat
     1801 gtattgcctt cattgactta ttacttgcgg ccgagttatg tacaaatcgt tgaagaagag
     1861 atgtcttggg aacgagcagt ggaggtggct tgccgaccgt tattggaaca tcaaatcatt
     1921 gactcgcgtt ttatcgctga ttgcttggat caaatcagac aaccgggata tgcaggttac
     1981 ttgggaatga agacttgcat tccccataca acggtcgata aaggtgtaat cagtgacggt
     2041 gtcagcattt tagtttgtaa aaagccgata cgatttccta atggtgaaga tgtcagcttg
     2101 attttgccgc tttcattttt tgatttaacg aagcatctgc gagccatcaa tcaaatcgct
     2161 gatatcgcca aagatgattc attgattgag cagttattga ttgctgatga cgaaaagaca
     2221 gtttatcaac tattaagaca aagatcttaa ggaggaaaac atgagactag cagattatcc
     2281 taaattgaca gtgatcatgc gtggttatac ttttgatcag gcagatgcta ttttacaagc
     2341 aatgcaggaa tttgaccatc aatttgccgt agagatgaca atgaacacaa aaggagctct
     2401 tgaaaatata catgaactaa atcaacgtta tggtgacacg acttatatcg gcgctgggac
     2461 ggtaaggaca ttagaacaag cccaagcctg ctatgaggct ggtgcaaaat ttttattagg
     2521 accacatatg ttcacaaaag aaatgttgtc ttacgccaat aagaaaggat tattggcggt
     2581 acctgccgca atgactcctt cagaagtcga ccgtatgttt aaagaaggag ctgatattgt
     2641 aaaagtattt cctgcagcgg ttgttactcc acgttttttc aaggatattc aagcaccttt
     2701 aggtaagtta ccactaatgg gggttggtgg aatcagtaag gagaatgcga aagagttttt
     2761 tgaacaaggt gctagctatt taggtcttgg ttccggtatg ttcaacaagc aagacatcga
     2821 agagctaaat gttaaaaact tagcacgttc gatgaaagaa ttaattgagg ctattaaata
     2881 ggagtgagga ctttggaact ttatttgaat gaggaactcg tttttcgaaa tgttcaagca
     2941 aaaacagata gtgaagtctt agcgttttta gcaagcgaga tgtacaaaaa aaactacgtg
     3001 aaggaggaat atattcaagc aatccaagaa cgggaaaaag aataccctac tggattacca
     3061 tcaacaccac caggaatcgc aattccccat gcaaactatg aaatggtcaa taaaacaact
     3121 ttagcaattg cgactcttaa agatccggtc ctatttcata atatggaaga taacaatgag
     3181 cagttaccaa tccaaattgt gatcatgatg gcgattgggg aaccacatgg gcaagttgaa
     3241 atgttacaaa aaattgttgg aatcatacaa gatgagccac tgcggcaaga aatgatcaga
     3301 gcaggcaatg atactgaatt attagaacta ttaaagaaag cggtttttta atataaggag
     3361 gaaatcataa tgaaacgaat tttagtagca tgcggaaatg gtatcgccac ttcaacagta
     3421 gtagcaacaa aagttagaga gtatttgcaa caacatggca ttgatgtttc aacgactcaa
     3481 acaaaattga tggaagttcc aggaaaagtt caagactatg atctattggt gacgactggt
     3541 caatttgatg gtcaaacagg tggtgtacca gtaatcaaag ggatgccgat tttaacaggt
     3601 atcggtgccg atcagacaat ggaagagatt ttgaacttac tgaaataata gctgatcaaa
     3661 ggagctgaaa aaatgaaaat cattatgaac gtctttaact tctttattga tgctggacca
     3721 acagttatgt tgccagtcat catcacgatt attggtttga tttttgggtt aaagatttct
     3781 cgtgctttta aatcaggttt gacattaggt atcggttttg ccgggatcaa gttgatattg
     3841 gactttatga cgaccaatgt tggaccagct gccaaggcga tggttgatcg aactggtgtt
     3901 aaactagatg ctttggatgt tggctggggt tcgattgcgg ctgttacttg ggcatcgcca
     3961 atcattccaa tcttgatttt tgccattcta ttggtcaata tcgttttgct gattttgaaa
     4021 cgtacacata cgctggatgt tgatatctgg aactatcacc atatggcaat cgttggtgtt
     4081 atagtgtatt ttgtgactaa gaatgtcttc ttaggtgtag gtgcatcagt agtgatggca
     4141 attgcgactt ttaagatttc agactggtcg caaccgatgg tagaaagttt cttcggaatc
     4201 cctggtgttt ctttaccaac tgtttctgcg ctttcatcac tggttattgc ttggccgtta
     4261 aattggctgc tggatcgtat cccgttattc agaaaatcaa aattcaccat caaagatgca
     4321 caaaaatatt tgggattttt tggtgattct atgatcatgg ggttagttat tgggatggtg
     4381 attggtgttt tagccggcta tgatatcaaa gcggttttac aattaggtgt cagcatgtca
     4441 gctgttttgg ttttgattcc taagatgact tcattattta tggaaggatt gatgccaatt
     4501 tcagatgctg cacaaaaatg gtcacaaaaa aaattcaaag gtacacgttt atttatcgga
     4561 ttggatgctg cagttgttgt aggtaatcca gatgttatca caacagcatt gatcattatt
     4621 ccactaacga ttgcattagc tttagtattg ccaggaaacc gtgtgttacc attcgcagat
     4681 ttagcggttg ttcctttccg cgtggcaatg gtcgttgcct tgactcgtgg taatttatta
     4741 aaaaatatca ttattggctt agttgtgaca gcttcattgc tatggtgtgg gtcagctact
     4801 gcgccaatgc tgacagcaat tgccaaatcg gttggtatta acttaggaac ttcttcaatg
     4861 ttaatctcat catttgctgc gacttccatg atccaaagtt atttggtatt tatcgcattt
     4921 gcttacaaac caatcatcgg tattccagtg ttgttattag cctttgcggg cgcatggtat
     4981 tacttcgatg gtatcaaaaa agttaatcat gaaatggatg aaccattgaa ggcacaatag
     5041 taggagggtt taaattgaaa atttcagatg tcacagtgta taaagtaaaa ccaagatgga
     5101 tttttgttaa gatctcgact gacgaaggaa tcgaaggctg gggagaaatg atctcaggaa
     5161 ctaaaacaga aacggttgtt gctggagctt atgagatagg aaaccggctg attggacgta
     5221 atccgtttga aatcgagcgc ctcttccaag aaatgcatcg atctttcttc cgaggcggtc
     5281 ctattaatgg aaccatcgtt tcgggtttag aaatggctct gtgggatatc aaaggaaaag
     5341 cgtttaatgt tccggtttat gaattattgg gcggtgcagc acgtgataaa atcaaggttt
     5401 attcttggat tggtggagat cgaccaagtg aagttgcaga acaagcacaa gatcggtttg
     5461 atcggggctt tacggccgtc aagatgaacg cgacagaaga gctgcattat atcgattcct
     5521 accaaaaagt tgatgaagtg gtggaacgag ttgcgtctat tcgcgaacgt tttggtgatg
     5581 caatggatat tggtgttgat tttcatggac gggtccataa accgatggca aaagtgctag
     5641 caaaagcttt ggagccattc catccaatgt ttttggaaga agtcgtttta cctgaaaatg
     5701 aagaacactt taaagaagta gctgattctg tggctgtacc attagctact ggtgaacgct
     5761 tgtacactcg ttggcaattc aagaacctct ttaaacaagg tactgttgat attatccaac
     5821 cagatgtggc tctttgtggg ggaatcttgg aaacccgtaa aatcgcagcg atggcggaag
     5881 cttacgacat ggctgttgcg cctcatgcgc catatggtcc tgttgcacta gcagcaactc
     5941 tgcaagtaga ctcatgtacg ccaaacgtct ttatccaaga acaaagctta gggatccact
     6001 ataacaaagg ttttgatctg ttagattttg tgaagaacaa agaagttttc caatataaag
     6061 acggctacgt agatctacct tcaaaaccag gtctgggctt ggaaatggat gaagacaaaa
     6121 tcaaagaaat tgcacaagaa ggtttgattt ggaccaatcc gcaatggaaa aattatgacg
     6181 gtacgatcgc tgagtggtga taaatgaaaa taaaggatga tgaaagatgg cagaagcact
     6241 tatgatcaca gtttttttag gactgctgat tattttgcaa ataatcgatc aaaagaaaat
     6301 tatcgtgttt gctcagagta gtcctgtaag gaagagtttg agtattttac tgacagtcgc
     6361 catcctgttg attttctggc cggaacatct gactgatcag attaaactgg ttgcttttgc
     6421 ttctgtcatt ttgatcaatg gttttttgaa ggagggtcta gcaaaagatt ctgttgttag
     6481 atttggagta ttgaacggta actttaatcg atatcctcaa gtccaagtag aaaaactagg
     6541 tgacgataaa tcatttattt cattttacaa aagcaagaat aattcttttt caatgatttt
     6601 tgataaagat caaactgaaa tgatggatgt ctttcaagaa cttgatatcc attccaaaat
     6661 tactttagat caaagttcgg aagaaaaaag agcagttgta aaaaaagata atgaatgatt
     6721 ctactaccga aattatgatt tctttatcac gaataatgaa acttgtttta atgaatcata
     6781 ttgattgaag tatacaatgt atattaagtt ttggaaagaa atatattggt acaagatata
     6841 gcaggaatcg attactcgat ccctgctttt tttaacttcc tttgcagcaa aaaaagctcg
     6901 taatctaaga gatgatggat agtttttaga atatatatat tttcttcaat tccagaaaaa
     6961 aatgaccaag ctagtatgct aaaaaagtac gatgcttcta tgatcttttt tccgtcttta
     7021 ttaacagatg ttttaattga tcaacgcata ttgtaatcta ccctaatttc catagttctt
     7081 caccactttt aaaaatagta aaacccctac aagtatgcta tagtaaattg ctaaagaaaa
     7141 accaataagg tgggagatgt gtgcgcgatc aaacaagcgg aaaaatgatt cgtttttatt
     7201 atacaagttt gcattttctt tattggatga tgttttgttc tgtctatggg tttgcgacat
     7261 tgtttttgat ttatttcaag attgatccag ctaaaatcgg agggatctta gcattggtca
     7321 atattgtttc aacggtgctt cagccttttg tcagtcaagt gatcatcaag aaaagaaaga
     7381 tcccactgat caccgtgctg aagacgatga tagcaggatt aggagtgatt ctcttagctg
     7441 gggtattgat tccgaatttg ccgatcatta cttatatctt gggtgggatt ttagtagttt
     7501 ctatgcaatc atttctcaat gcgctggcat ttgagtattc aaataccggc tacaggatca
     7561 actttggctt ttcaagagct ggtggttcat tttcttatgc tgtaacttct tttttactgg
     7621 gacagctgtt agcgatttat tctgccgcga ttttgccaat cttggttata gttgaagcag
     7681 tgatattttt cgttattttg catctgctgc cggatgtaaa aaatcaagaa gtttttccta
     7741 tgacaaaaga acaggatcgc tcagtttctt tgagaaaaaa atatcctttc ctgattttgt
     7801 tatttttagg tttcagtttt ctttttactt tccacaccat gatcaacagc tttttggcac
     7861 agatctttga aaatatccac ggcggcagta aagaagttgg catcgcattg atgatcgccg
     7921 ctttatgcga attaccggga atgatctttt ttgaacagct tgtcaaaaag aaatccagca
     7981 aattttggct gtctgttgcc agtatttcat ttgctgtcag aggattcatg atgctgctgg
     8041 ccagttcgat cctgatgatg gaaatgacgc atctcctaca agccttcagt ttcgctttgt
     8101 ttattccagc ttcggcttat ttgttcaatc aatttctggc ggatgatgat cgtgtatttg
     8161 gacaaacgat gatcatcatc gccacaactc ttggtggggt gataggaaat gtcttgggcg
     8221 gcagtctgct gcagcatttc ggtgtatggg agatgctgat tttcggtact ggttttgcgg
     8281 tgctaggtgc tttattaact attttgggca ttcgaaaaat accgaagaca ggaaacgata
     8341 gtgattctct tgttgagtag cataaaaata cttagatact agttttatat aaataacata
     8401 tagtgattat tggcgtaatt acaaaaaacg agaataactt aagtaagcat ttctaaataa
     8461 ttgagaaacc tcatctaaaa agataagaaa atatccctaa taaaacttct gtaacatttt
     8521 agataactga ttgtaatctg aataataaac tataaggaga cggttaggcg gtctcctttt
     8581 tttgcgtatt ataattctag aattgttgga aattgataat aattaacaag aaatattaga
     8641 caggaacttc gaactgctta tcacattctt attattatat atttgcgtaa gtagtcctgg
     8701 tagtctcaat gcactattct atcttgaaac taagaagtta tagaaggagc aatgatagaa
     8761 agcacgagaa tacaaatagc gattaaatat ttttctagac aaccttagtt aattcacaca
     8821 gatatatttt aggtacagtc ttacagatat agagttagtg ctgtgtgaat cctgatgttc
     8881 gcagtgcata ggagtcaagt aagattctag ccagtataga aagtggaagt ctggagcgta
     8941 cctcataatc tgggaagaag gagccttctg atttaaagcc aacaaaagga atctcgatat
     9001 gttccatcaa acttgaatga cgattagcag taagcaaaat tgtcccgatc tcagctttat
     9061 aacagttttc agctgcggta gtcaattcct ttgtttcacc gtttagtgaa acaaagatca
     9121 cgatgtcatc tttggataat tttctactaa tgttttttat gatattggga tcagtatgca
     9181 tctcacaata tttaccggta agttgaaatt tgaccatcat ttcctgagca atcaattctg
     9241 aaaaacctcg ggcaaaaatc atgattcttc tagcagcctt gattcgttga atagcatctt
     9301 caatattccc gctttctacc atattgatgg tgcggattac ctcttgctca tttttaagaa
     9361 tagcagtctt tattccttca tcaactttat caagagcggc aaaattgata tttgtatttt
     9421 ctttttcttt taacgaatgt ttaaaagacg taaacccctc atatcctttt ttcttcatag
     9481 tacgaacgac ggttgctgtt gaaacgttgg catattcact tagttttaca atggaatagg
     9541 aggggatttc gagtatgtga ctttgaataa aatcccagag atatttctcc gattcactta
     9601 attttgtatc catattttgc ctccgattag ttaggataat tctattgtaa agcgggagtt
     9661 tcctttactt caagtttatt taatatattt tgtaaaagtt ttcaatgaat ttagtcattt
     9721 atgaaaacat ttacattcga tcttgataca taatgaatat gtaagaaagg aggagcgtaa
     9781 atgtcagttt atacatgtac tttaaacttg gcaatcgacc tttttatcga aacagatgaa
     9841 atgaaaccat cccaagtcaa tcgaacaaac gatgatgata tacaagctaa tggaaaaggt
     9901 gtgaatgttt cattgatcat gaagcaatta ggtatcgata gtacagcttt aggatttaaa
     9961 gcaggtttta ccgggaatta tattgaggat tatttgcatc aaaaagatat tagcactgat
    10021 tttattagcg taccgggaat gactagaatc aacgttttta cacaagttaa taaaaccaat
    10081 gaagaattca aattggttaa taaaggacct gagattcctc aggaacaaat caaaactttt
    10141 ctaaatcaaa tacaaaagct gcaagctgac gattatttgt gtgtttctgg cagtttgccg
    10201 cgaggggtct cacccgaaat tcttattgat atcagtcgta tttgttttga aaataaggtc
    10261 catctgatta ttgattcaag ctatccggaa ataattgatt gtctgccgta tcagccgttc
    10321 ttattaaaac caaacgagga ggaattgcaa tcttggtata atgtcgagct tagtgatcgt
    10381 gaaggatata ttcattatgc tgaacgcttg attgccgatg gagcgaaaaa tgttctcctt
    10441 tctctaggag gagagggagg aatattttta aataaggata tcgtttattc tgggaattct
    10501 cctaaaggta aagtagtcaa tacagcgtgt gctggtgaca ctttgttggg aacatttctt
    10561 gcaggatatt taaaaggtga acaggtagat attaatttga agaaaagttt agcagctgga
    10621 agttcaaccg cttttcgtaa aggattaaca gatttttcgg atgttgcaga gttggaaaaa
    10681 caaatcgaaa tcaaagaggg agcgagtaaa aaatgacaac ttacaaaatt gttgccgcaa
    10741 caggatgtcc aacaggaatt gcccacactt atatggctca agaagcattg gagcaggcag
    10801 ctaagcgcaa aggggtatct atcaaagttg aaacccatgg tcaagtaggg atagagaatg
    10861 aattaacacc agaagaaata aaaaacgctg acgctgtaat cattgcagct gacaaagatg
    10921 ttcaagcaga acgtttcgca ggtaagcgtg taatcgatgt gcctgtcagc aaggggatta
    10981 aagatgctga ccaattgatc gaagatgcgt tggctggtaa aggttcaatc actgcagaaa
    11041 acaaaacagt tgacgctgct ggtgagaaag cggagatggg ggttgcagca ggcattggtc
    11101 acagtattta taaaaatctc atgaacggtg tttctcatat gctgccgttt gtagtggcag
    11161 gtggggtaat tattgcaatt tcgtttgcca tctggggtgt gtactctttt gatcccaatg
    11221 atcctactta caatccgact gccgctatgt taaagggtgt tggtgatgcg gcaatgggaa
    11281 tgatggttcc tattttagca gcttatatcg ctgaaggaat cgctaaacgt cctggtttgg
    11341 ttgttgggtt tgttggcgga ctgttagcca attctggcgg agccggtttc ttaggcggaa
    11401 tttttgcagg tttcttagca ggctacttta tcttactatt gcaaaaggtc atgaaaggct
    11461 tgcctaaaca attggatggt ctgaaggcga tcttcttata tccggtgatc ggtgtcttgt
    11521 ttgttggtgt agtcatgtct ttattagcaa atccaatgga agcagtcaac caaggaatga
    11581 tgaatttctt ggcaggattc caaaattcta atccattaat tttagggatt atcgttggct
    11641 gtatgtcagc atttgatatg ggaggtccag tcaataaagc ggcttatgtt acagggactg
    11701 cgttgttggc acaaggtaac catacattta tggcaggggt ttcggcagct tgtatcgcgc
    11761 ccccattgat tactggattt gccgcactgt tttttggaaa atatttcgac acgaatgatc
    11821 gcaacgctgg tttagtcaac tttatcttgg gctcaacgca cattaccgaa ggagcaattc
    11881 catttgcggc taaagatccg ctgcgtgttc tgccaactat gatgctaggt tcatcaattg
    11941 ctgctgtact gacatatatg tttggtgtcc aagttcccgc acctcatgga ggttttctag
    12001 tattacctgt tgttactggt aaggttgcat gggtagggtc gattttactt ggttcaatcg
    12061 ttggcggagt aattttaggg ttgatccaaa aacgtagtgt agaaaaacgt gaagcagaag
    12121 cagctgctgt tgaaatgaaa gaagcaacca acaactaaag gttattctag aaagaaggat
    12181 ttcaaatgac tttgatcaaa acaaataaag tttttatgaa taaaaatttt acgacgcaag
    12241 atgaggtaat gaacttcctt gcagatcagt caattgtctt gagcattagt gaagaccgag
    12301 atgcagttta cgaaaaattg atggaaagag aagaagaaag cacgactggt atgatggatg
    12361 gttttgccat ccctcatgcc aaagatgcta gtatcaagga tgccgatatt gtgattgttc
    12421 ggttaaacgg taaggtcgat tggaaaagtt tagatggaga aggaacggat tttgtaatcg
    12481 ctctgtttat tccagattca gaggctggaa caacccatct aaaattttta tctcaggtag
    12541 ccagactttt gatgcacaaa gatgtgacag aaggtctgaa acaagcccag tctgctgaag
    12601 aaatagctga acttttaaac caaaaattag aagaaaacta aaaaggaagt agtgaaatca
    12661 tgcctttaac agaaaaaaag aaaacttata ttcgtcaact aagtaatgaa agtggcatca
    12721 tcagtgcgtt agcaatcgat caacgtggtg ccttgaaaaa aatgatcggt aaatttcaaa
    12781 ataaatcagc aaccgatgaa caaatcatca atttcaaaaa aatcatttct tctgaattga
    12841 ctccatatgc ttcagcaatc ttattagatc cagaatatgg gttgccggca gccgaagttc
    12901 gcgataaaaa tgctggtctg ttgttggcct atgaaaaaac tggttacgat gcttcaactc
    12961 caggacgttt accggatatt ttatctattt ggtctgtaaa acgtctaaag gagcaagggg
    13021 ccgatgcttg taagttcttg ttatactacg atgtagatga atctgatgac atcaatgacc
    13081 aaaagaaggc gtttatggag cggattggtt ctgaatgtgt tgctgaagat ttgccatttt
    13141 tcttagaatt ggtttcttat gatgccaacg atcctgatac ttcttcgaag gaatatgcct
    13201 tgaaaaaacc gcataaagta aatgaaatga tgaaggaatt ttctaagcct cgctatggag
    13261 ttgacgtttt gaaagtggaa gttcctgtta atatgaacta tgtggatggt tacactaaaa
    13321 atgaagttgc ttataccaaa gaagaagctg ctgcttattt caaagaacaa tccgagacta
    13381 ccaacctgcc atttattttc ttgagcgcag gagtaactgc tgaattgttc caagaaacct
    13441 tgaaatttgc aaaagaggct ggctctacat tcaatggggt actctgtggg cgcgcaactt
    13501 gggcgaatgg tgtagaacca ttcgttacta aaggtgaata tgctgccaaa gaatggatgc
    13561 agacacaagg acgcaagaac atcgaagagc tgaataatgt tttgaaagaa acagcaacag
    13621 ctattaaatt gtaagaaagc tttaactata accttaagtt tgtaacctaa tgatttttaa
    13681 taatcaattt gagcttttaa ataaagaatt ggaagcgtcc cgacgcttcc tttttcgttt
    13741 gtttttaagg catgataggt tctatgttgt cgttcaataa gcgcaagaag gtcagcattt
    13801 ttttcttaga gtatgcaaaa ttgcttttct acccaatgat ttaaaacgga gaggcaccct
    13861 tggatatggt agatggtgaa gtaacgcatt tcttctgtga tcacggtttt tttgtcttct
    13921 tgtagccaga tttttaaata attttcttcg atcagattat ttaatctctt ttgaaattgg
    13981 atatctccgt ggttgatgac gaataacttg tatacgaacg tattcgtata gacatagtcg
    14041 atcaattgag cgtatagatc ctcgtagcta tgtgtcgtat cgtaggaaat gatttcatcc
    14101 aagtcttgga aaaagctatt ttccagtttt tcataaagat catagatatc cgtataatgt
    14161 gtataaaatg tcgaacggtg aagatcagca gtttcggtca gttcacggat ggtgatgttt
    14221 tgaatttttt tatctactaa taattttgat aatgcttctg ctaacgcttt ttctgttttt
    14281 ttgacgcggc gatcctcttt tttcattttg cagcctccta atcaacataa tcaaggaatt
    14341 gtgtcggtta tccgacaatt tcaccgctat ctgaacatag ataaccgaca ccttgtctat
    14401 tataatataa gtatagcata tcaatattta aagaatagga gaataagtga tggaattagc
    14461 ctttaagcaa ctggaaaaga aagactacaa aaaagccatt caattcgcga ttaaaggtat
    14521 gcactttgat tggtatacca agaacaaact ccttttgaat ctttatggaa gatacttttg
    14581 gtatctagaa ttgaatcgcg cgacacaaat cattgcttta tatgcggatg atgagttggc
    14641 aggtgtttta ttagcagaca tcaaaggaaa atcaaaaaag catcattcat ttagtcaaaa
    14701 gttatatgtt aaactatttg atttcttaca aaatgcattt gtgaaagaca gcaaaggcgg
    14761 gtatgacgac accaatgacg aattgctttc agactattta aaaaaacatt ccccagatgg
    14821 agaaattgtc tttttagctg ccaaccctga tttaaagatc aaggggatcg gtagtaaatt
    14881 attaaaagaa tttgaacgcc gagagcaagg aaaagaagta tttctgttca cggatagcgg
    14941 ctgtacgtat caattttatg aacgacgcgg tttcgaacgg aaaaaagaaa aagataacgt
    15001 catgaagatc cttaataaag aagtagatct ccgctgtatg ttatatagta agatcattca
    15061 gtaatgtttt ttactatcag aaagcagaag taccacgaag gtcaatggaa aaagcgagta
    15121 attgatccat ttagatgaag ataggtgtag tctcaaagat attagctggc aaagatatcc
    15181 ccagttaaaa atagatttct gtatccaaca ataaaaatat ttttgtattt attagtatat
    15241 atactttaca aaaatttgta tatatactaa tttttttgta ggatcaatga aatgagggga
    15301 aaatatgcca aaatataaag aaatagcctt ggctctaaaa gagaggatcg ttgagggaaa
    15361 atatcaggaa ggttctaaat tacctgagca agaaagtctg gctagagagt ttaaaacaag
    15421 ccgtgttact atccgcaaag ctatacaact ccttattgat gaaggtttgt tatatacgag
    15481 acgtggatct ggtactttta tacgaagcaa tatcagacag gacaatgaga atgtcactca
    15541 agtaaataat gtatttggca cttcctcaca agaaaataca aatgtgacaa gtaaaataat
    15601 ccgttttgat gtccggtttc cgacagatta tgaaaggcgg ctttctgcaa cctacttccg
    15661 atccccttcc tgcaaatcat gggtataaaa aataggcata ttaagcgggc taggaggaga
    15721 aatattcaca tatcattttt tcattccgca agctgcgtca agttatttgg aatttgtaga
    15781 acagatgaga gaggtagaag cagcactaca aactactttt caataagtag gaattataga
    15841 aattttactc aaaaaatctt cattaaaaaa tctgactaaa taagttgaga aaacagaata
    15901 tacttcaata tccagtgatt tataaatatc attcactcat gatacccagc tccgtatcat
    15961 aagtgatgcg gtttttatca ttgatcctaa aaatcttagc aagacaaaaa gtacgtaaga
    16021 aagtaaagac taaatacttc ggaggaacaa atgaataaca atgataggtt attgcgattg
    16081 cgttatgcga ttgatttgaa agatacggat ttgattaaag cttttgagct aggcggtgta
    16141 ccactgacta aagaagaagc tcaggcggta ctgaccaaag tacaggataa gaacaaagat
    16201 aatgcagaaa ataatgtgta tgaaaaaacc atcaacaacc aagtttttga cgcattccta
    16261 aatggcctga ttctcttggc gcgtggtccg caaaaagata agccgatagt agacacgccg
    16321 caaaaaagca aggaaatcaa atatatcaac aatgtgttgc taaaaaaatt aaaaatcgcc
    16381 ttgtctatga ccactgatga tattttagaa gtttttgctg aggcagaact ctatccatca
    16441 aaaggcgaaa tcggggcatt tttgagaaaa gaaggccaac gaaattttaa gccttgcgga
    16501 gataaatata tgcgtaattt tctcaagggg ttaggaattt ataatcggag aaaagtataa
    16561 agaaatttca tgagaaatca aaacaatggt tgttttgatg agagctagtt tttgtatgag
    16621 attaaaatat tatcttaatc gaggagctgg attggtttta tgaatgatga atataagaat
    16681 gatgaagata agatgctttt tgaagagata gagaatcgat gtaggctcaa ttttgagctt
    16741 cggggaaaga tgtctttaat acaacaaaaa aagtatttag cgaataaatc agagtttact
    16801 ctgggacatg ttgaaaaatt aatctcggat tggattagta gtagaagcga atttacaaaa
    16861 ataaaacagc cgattaaatt tgacatgaaa aaacttttgt taaataagag tgagataggt
    16921 aatagagatc aatatattag agctaaaggg caagaaataa ttgattcatt aggtgaagtg
    16981 aggtcataca attatttgta tgtaacacat agagctgatg gaatggtcat tactgtgggg
    17041 aaatcttctt ctaatgatat ttttttagat ggagatcttt tttatcaact caatacaaat
    17101 cacttgtctg gcactgaaaa tataatttta aggacggaat atggcaatga aatatttgca
    17161 aaatatgatg agattttaaa aaattatttg gactgggctt ggataattcc ggttgagtca
    17221 ggagatgcta agaaactgga gagattattg ggcgatgaac taattaataa aaaagtacca
    17281 attttaaatt attattccca tagacaataa aaggctattt ttcatgataa tactagttat
    17341 aactgtaaaa atggaagaaa atctgggaaa gaagttttta aataagtgta ttgttcgatt
    17401 ttaataaata ataagcaata ccatccgtct gtgttgcgca acatcgtact acaatgaata
    17461 ttttttcaca aaaagaaaat catccatcga atgaatggaa ggttttagta tacacgaggt
    17521 taatgtcccc tcttttataa tcagaggagt gaggtttttt ctatgaatgt ttctattttc
    17581 ttattgctag tctagtttct cttacgatga aattgggatt ctattccagt ttttattgat
    17641 ttgctgataa aataacttga atggtggata taaacatgat aaataagaga agaataacaa
    17701 aacaaggttg tgaaatgatt ctcaaataag tataatagaa agaaaaagga ggaagaatca
    17761 atgaaaatag caattgcagg cgctggcgca atgggaagtc gctttgggtt aatgcttcac
    17821 caaagtggga acgaagtatt attaatcgat ggctgggcag aacatgtcca acaaatcaaa
    17881 gaacatggat tacaagcaaa ttttaatggt aaagaggtag aagcaaaact accaatcgtt
    17941 cttcaatccg aagtagaaaa agaagatcaa gttgatctga ttattctatt taccaaagcg
    18001 atgcagctgg aaaaaatgct gcaggatatc caatcattaa tcaaaaaaga tacagaggtc
    18061 ttatgtctat taaatggtat cgggcatgaa gatattattg agaaatttgt accaatggaa
    18121 aatatctata ttggaaatac catgtggacg gcaggtcttg aaggtcctgg tcaggtcaaa
    18181 ttatttggaa gtggttcagt agaattacaa aatttaggtg atggaaaaga agcagctgca
    18241 aaaaaattag cagacaaatt gtctgaatca ggattaaatg ctcatttttc tgacaatatt
    18301 cactattcta tttatcgcaa agcatgtgtg aacggaacaa tgaacggact atgcacaatc
    18361 ttagacgtta atatggctga gctaggaaaa acatcgactg ctcataaaat ggtggcgacg
    18421 attgtcaatg agtttgccaa agtagcagca gtagagaaga ttgaactaga tgtcccagaa
    18481 gtcattgcac attgtgaatc ttgttttgac ccggaaacaa ttgggttaca ttatccttca
    18541 atgtatcaag acttgattaa gaaccatcga ttaacagaaa tcgattatat caatggcgca
    18601 atttctagaa aagggaagaa atatggtgtt gcgacgcctt attgtgattt cttgactgag
    18661 cttgtccatg caaaagaaga tagtttgaac gtaaaataaa ggagagattg aatggaaact
    18721 tcacaaaaaa tatcaccgaa aatttttctg aataaagtcc tcgctggtac agcaacagga
    18781 atcattattg gattgattcc taatgcagta ttaggtgcta ttttaaaata ttttagtgcg
    18841 tatccctttg cggtaacgat cgcacagtta gcagttattt ttcaattagc aacacctttg
    18901 atcattggtg gtttgattgc cttacaattt ggatttgatc cgatgagaat gatggttgta
    18961 gccggagctt cttttgttgg ttctggtgta gtcaaattca cacctgattt gggtgaaacg
    19021 ggtgtttacg ttggtgctgg tacaggcgat attattaata cgatgctgac agcatcgatt
    19081 gctgtcgggc tgattttact gattggaaat agttttgggt cagtgtcgat tgtgttaaca
    19141 ccgattgttg taggtgtagg tgcaggttta cttggttttt atttattccc ttttgtaaca
    19201 gcaattactt ctgcaattgg atcattgatt aataacttca ctaccttaca accgctgtta
    19261 atgtctatct tgattggttg ttcctttgcc tttttgatta tctctcctat ttcaacagta
    19321 gcaatcggaa tggcaatcca actagatggt gtttctgctg gtgcggctgc gatgggcgta
    19381 gctgcaacca cttttgtttt agtagtgaac tcttggaagg ttaataagtc aggtgtgaca
    19441 attgcgattg ctttaggcgc tatgaagatg atgatgccta atctatttag aaaacctgtg
    19501 attcttattc cttgtttagt tagtgcagtg attacagcta ttcctgtcgc tctattttct
    19561 atttcaggta cgcctgcttc tgctggtttc ggtgtggtcg gacttgttgg tccgttggct
    19621 tctttagatg cagggctaaa tggctttctt gttgttcttt gttggttagt catccctgtt
    19681 tttgcggcac taattactca atttttatgc gagaaagtat ttaaactgta tgatcgagaa
    19741 gaagtcttca aatttttagg ctagtagatt ttactaagaa attttcaatc aatggatgcg
    19801 taagtgagat gtcaacaaca tctgacttac gtttttttgc caaaatatgg tttttatttt
    19861 ttattattag gtgtgattag tgatttatcg acaccgtata tccttggcct tttttatccc
    19921 aaactgaatc aaatgactac cgtaattagt gtgtttggtg acgtagatag tccagtcaga
    19981 cgtgctttct tggtctggtc agttgtatct ggactttttt ttgttctttc gttgcctgcg
    20041 ttgtatcacc tatttgttgg aacatcaaaa acacttgcaa tacttgctgt tgcaacagtt
    20101 ggtttatatg ggataggtga ttgtattttt actgggttat tcagtatcaa tacgaatgaa
    20161 agctcttgga atctatcgac ttggatccat aatacaggtt ctgggctagg ctatgcaggc
    20221 tttctacttt tcccattgtt acttgttctg ctttatcgtc aa
//
LOCUS       DACDAF010000051        19558 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.051, whole genome shotgun sequence.
ACCESSION   DACDAF010000051 DACDAF010000000
VERSION     DACDAF010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 19558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19558
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.051"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            617..1945
                     /locus_tag="IVZ69_001712"
     CDS             617..1945
                     /locus_tag="IVZ69_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HAP8183794.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            2147..2980
                     /locus_tag="IVZ69_001713"
     CDS             2147..2980
                     /locus_tag="IVZ69_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HAP8183795.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            2996..3733
                     /locus_tag="IVZ69_001714"
     CDS             2996..3733
                     /locus_tag="IVZ69_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HAP8183796.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(3888..4856)
                     /locus_tag="IVZ69_001715"
     CDS             complement(3888..4856)
                     /locus_tag="IVZ69_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HAP8183797.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            5088..5921
                     /locus_tag="IVZ69_001716"
     CDS             5088..5921
                     /locus_tag="IVZ69_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HAP8183798.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            5955..6794
                     /locus_tag="IVZ69_001717"
     CDS             5955..6794
                     /locus_tag="IVZ69_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP8183799.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            6820..7380
                     /locus_tag="IVZ69_001718"
     CDS             6820..7380
                     /locus_tag="IVZ69_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP8183800.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            7579..9300
                     /locus_tag="IVZ69_001719"
     CDS             7579..9300
                     /locus_tag="IVZ69_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HAP8183801.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            9465..10607
                     /locus_tag="IVZ69_001720"
     CDS             9465..10607
                     /locus_tag="IVZ69_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP8183802.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            10623..11834
                     /gene="thiI"
                     /locus_tag="IVZ69_001721"
     CDS             10623..11834
                     /gene="thiI"
                     /locus_tag="IVZ69_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HAP8183803.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            12407..13054
                     /locus_tag="IVZ69_001722"
     CDS             12407..13054
                     /locus_tag="IVZ69_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HAP8183804.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     gene            13447..16092
                     /locus_tag="IVZ69_001723"
     CDS             13447..16092
                     /locus_tag="IVZ69_001723"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HAP8183805.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            16402..17715
                     /locus_tag="IVZ69_001724"
     CDS             16402..17715
                     /locus_tag="IVZ69_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HAP8183806.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            17705..18358
                     /locus_tag="IVZ69_001725"
     CDS             17705..18358
                     /locus_tag="IVZ69_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP8183807.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            18413..19105
                     /locus_tag="IVZ69_001726"
     CDS             18413..19105
                     /locus_tag="IVZ69_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="JAB domain-containing protein"
                     /protein_id="HAP8183808.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            19255..19455
                     /locus_tag="IVZ69_001727"
     CDS             19255..19455
                     /locus_tag="IVZ69_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP8183809.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT         6586 a         3301 c         4145 g         5526 t
ORIGIN      
        1 ttcgagtcct actgccggag taaataaagc ttatgcaaag aaaaagaaat ccaatcactt
       61 gggtttcttt ttcttttatt attatgatga atcaagcttt ctgtttttgt cacgtatgtt
      121 gtaatcttta cgaaagagta gagttggcta ctcataatca accatacttc ccatcatcgc
      181 taaatacgaa ataaatcagc attcctacac caatcaaagc acaagctgca ccaagaaaag
      241 ggatgacatt cccaaagtta tctgtattca taagtatgcc accacccaca aacaaaaagc
      301 cgccagcaat caggtttttc attttattca tctcctttct tacgttatag tatttccttc
      361 tttcaatgag tattttgaaa gctatcttat tgtatgatgt tcttctaggc ctcttcttta
      421 ttatacaggc cattttcgtt atctcataga aatattcctt tttatctgaa aactattgta
      481 taccgtatga catttttctt catgaagttg taagtatatt ctcattcaaa tgaaaatttc
      541 atcatagaag agattgtatt tctaaattct taagagtaaa atacgaagta taacttggat
      601 ttggaaggat gattggatga aagctattac gcctgatatg acaacaaaat ttaacaaaca
      661 gtttcaagca aatatcaaac agcaggcatt gcagcgggca gttgtgaaga acggaattac
      721 tgcttctgct gaaaatgttt cagcacatgt ggagaataca ccggtatttt ctatagattt
      781 ggctacgggg aaagtggcta atcaaatgca atcggggcgt tgctggatgt ttgctgcact
      841 gaacacattc cgtcataaga tgctgaatca attccattta aaagagtttg aattatcaca
      901 aaattacact tttttctggg ataaatatga aaaggcaaat tatttctatg aaaacatcat
      961 tgcaacagga aaagaggcaa tcgatagccg gaaagtagct ttcttactcg ctactcctca
     1021 acaagatggc ggccaatggg atatgatcgt ttcattattc caaaaatatg gcgttgtgcc
     1081 taaatcggtg atgccggaaa gtgcgaatag ttcaaattct cgagatttga ataactactt
     1141 gaacaaatta ctgcgtaaag atgcagtagt gttacggaaa atggttgctc aaggagaaac
     1201 attagacgct attgaagaaa agaaagaaga aatgctagaa agcatttata acttcttagc
     1261 tatctcatta ggaacacctc caaaagaatt cgattttgag taccgcgatg aagaaaagaa
     1321 ctatcatctt gaccgaggac tgacaccaca aattttttat gataaataca tcggtgtaaa
     1381 attagatgat tatgttagcg tgatcaatgc accaacaaaa gacaaaccat tcaatcgttc
     1441 ttatacagta gagatgctag gaaatgtcgt tggcgggaaa gaagtcaaat atctgaatgt
     1501 tgatatggaa actttcaaaa aattagcgat tgctcagctt gaagaaggag aatctgtttg
     1561 gtttggttgt gatgtaggtc aatcttctac tagaactagt ggcatcatgg ccttagatgc
     1621 ttattcaatg gatgatctat ttgatacgga ttttacaatg actaaagctg aacgtttaga
     1681 ttttggagaa agtctgatga cccatgcgat ggtattgacc ggtgttgact tagtagacgg
     1741 gcaatcaaca aaatggaaag tcgaaaatag ctggggcgaa aaagttggaa agaatggctt
     1801 ctttgttatg agtgatgcct ggatggacga atatacgtac caaatcgttg taagaaaaga
     1861 tttattgacg aaagagcaat taaatgcgtt caatgaagaa ccaattgttc tatctccgtg
     1921 ggatccaatg ggtgctttag catagacgag tatttcaatg aagagtatgt agtaaagata
     1981 aaaagagctg gcttaagcca gctcttttta tctttaaagt ccattccctg ttttttatgg
     2041 tccctgtgct ataattctaa ataaaggata aggattggaa ataatccttt tatcattaaa
     2101 aatatgatga cgaagtagaa taaaattggg agtagggggg aaagtcatgg atatccaaac
     2161 tgttttatct gatctgaaat taaatggtaa agtgattcca gttgttggtg gcgatgttaa
     2221 tcagacctat cgtataaaaa ccgaacatcg tgcttatttt ttaaaaatcc atccgaatgt
     2281 aaaaaaagga ttttttgaag cagaagtaga cggattaaaa gaactgtcag cattcgtacg
     2341 tgtaccggat acgtatatgc taggtgaaac aagtgaaggc gcttatttgt taatggaatg
     2401 gatcgagccg ggaaaagggg atcaacgaga tcttgctgca gctttagcta atctccatca
     2461 gcaaacagcg ccacaatttg gttttcgtaa agataactat ttgggtacac ttgttcagaa
     2521 aaattctttt gaagaagatt ggtggacttt tttctttaaa gatcggcttg aatcccagat
     2581 ttctttggca gaagaaacga atcgatggaa tgtacagcgt caagaaaagt atctgcgatt
     2641 taaagaacgt gtattgaaat cggttgaacc aaaaaagatc actccacgcc tcttgcacgg
     2701 agacctgtgg agtggtaatg tgttctttga ccagcaaggg catccagttt ttgtcgaccc
     2761 agctgtttct tatgggaatc gggaacaaga tattgcaatg agccagttat tcggtggttt
     2821 ccgaccggaa tttttagatg cttatcaaac tatatttcca ttagaaaagg gatggaaaga
     2881 ccgactgccg atttaccagt tatattatct tttggcacat ttgaatatgt ttggagaaag
     2941 ttacggttcc caagtagatc aattactaga aaatttttaa gaggagggcg tgtttttggc
     3001 aaaaaaatat accaaaaagc atgaagtttc atattatgag tgtgacatca accaaacgat
     3061 gacatttcct tcgatgttag gagtagttat caaaacgtct gaagatcaaa gcgaccagtt
     3121 gggaagaggc agtgaattcg tcaatagctt tggacttact tgggtcatca cgaattattc
     3181 catggagatt aatcgtctcc ctagagtcgg tgaagtaatc tcagtaacga ctcaagccat
     3241 ggagtacaat aagtttttct gttatcggaa cttctggatc catgatgaag atgggaaaga
     3301 attagtcaaa atagaatctg ttttcgtatt gatggatttt gtgaatcgaa aaatgagcag
     3361 tgttaatgaa gagatcattg ctccttttga gagtgagaag atcaagaaaa tcaagcgtca
     3421 ggaaaaaatt gaaaagattg attcgggctt catgttgcca tatcgtgttc gtttttatga
     3481 tatcgatagt aatcagcatg ttaataatgc gatgtatttt aattggatca ttgacgtatt
     3541 aggatatgac tttttgacta cgcatgttcc agaaaaagta attattcgat ttgataaaga
     3601 agtagagtac gggaatgaga tcgaaagcca ttttgaacaa atccctatcg aaaatggtgt
     3661 caaaacaaaa catgaaatcc gaatgcaaga acagctgtat tgtgaagcaa atattatatg
     3721 gaaaaataaa taaaaaagag gttgtgacag aagggggcaa cttcaagaaa taagaagaaa
     3781 tttacgaaaa ttgtttctca aatttttgta aattttcgac ttagttttcg aagaagctat
     3841 ttttgtcaca gcctctcttt ttaagtttag ctattagata atgatgttta gttttggata
     3901 aacgaaatca attcttcacc cgacaaacca tagtttacag caatcaatag ttttaaacgt
     3961 gctttttgac tattaatact gttacagaaa ataatcccca ttttttctag ttcttttccc
     4021 ccgccttcat aatcataaac aggctctgcg attccattga aacaacgaga aacaagtact
     4081 acagggattt tttggacaag aagcttttcc aaagcagcta aggcttgtgg agggagattc
     4141 cccgcaccta aagcttcgat taccaaaccg tctactttcg tatgggcgat ggcttccaat
     4201 aagtcccctt gcatcccagc atatgcttta acgatcggga tagtcccatc tacagcggaa
     4261 atgtccagtc gctttgtttc taaaagttcc tgcaagaata aaattcgatt cttagttact
     4321 aagccgatgg gacccaatgt aggtgttcgg aaagtagcaa catttgtggt atgggtcttt
     4381 gtcacgtagc gtgcagaatg gatctcatcg ttcatgacca ccaaaacccc cttatctagc
     4441 gcttcttcac aacttgcgac acgaatcgca ctttcaaaat tataaaggcc gtcacttcca
     4501 agttcattac ttgaacgcat tgccccagtc aaaacaattg gtaatttgtt gccaatcgtt
     4561 gtatcaagaa aaaaagcagt ttcttctaat gtatctgtac cgtgtgtgat caccactccg
     4621 gatatacctg atgcataagc ggacaagata cgttctttta ataccaacat gtgagaaggc
     4681 atgatgtgtg gtgagggaag attgaagata tcttcaacta ataattctac atgcttgggg
     4741 attgtgattt ctgcatctaa taatgggttt gccacatcag gactaacacc gcccgtgagc
     4801 atgttttctt tcatggcgat cgttccgccg gtgtgtagta caagtatttt tttcatttta
     4861 cagacttcct tacgaataat tttgcatagc cgttaaatct tattgtatac tatataaaag
     4921 agttttgcta tcagtgaaga ataacgaata gcctaactta tcataaaaaa gctgacctta
     4981 ttaaaatgga aaagactcaa ccttgacctc ctaatacaat ggagtatctg gttgagtttc
     5041 ttttacaaga aagcagccaa ggaaatcaat cacgaaggtg gccggaaatg atcagaatcg
     5101 gattaacatc gtttaaagaa catgacaaat taactggtaa aaagaataac actctttatg
     5161 aatatgcagg gtttctaccc ttagtggaat tagatactgc ctattatgga attccccgaa
     5221 agtcctcagt tgagaattgg ataagtgaag tacctgaatc atttcgcttt gtagtcaaag
     5281 tctatcaagg aatcagcggt caaggagact ggaagcctta ttatcagacc gaagaagaga
     5341 tgattgcgca ttttttagat gttatgtcgc caatggtaga tgctggaaag atgttttgct
     5401 ttttagtcca attcccctca tcattcaaat gtacgaaaga aaatgtccag tacttgcgca
     5461 aacttagaaa gtggtttgag ggttatcctg tttctataga attgcgggat tattcttggt
     5521 acagcgatga atttcttgaa cgtacaagaa actttatgtc tagagccgct ttttctttag
     5581 ccatcatcga tgagccacag ttgctgaata caacgattcc ttttgatcca tttgtcacca
     5641 atccgaactt tgctcttttt cgattccatg gtaggaatgc gcaaggatgg caagcaaatg
     5701 ataaagagtg gcgtaaaaaa agaacgttat atcgttattc agaaaaagaa ctgcaagaac
     5761 tagcacatga agtcaaagta gttgattcta agacaaaaga ggtaggtgtg atttttaata
     5821 ataattctgg tggtgatgcg gctgaaaatg cattagcact gcaaaaaata ttaaatatca
     5881 agccagatgg actcaatcca acccaaatgg atctgtttta agggcttatt ttattcaaga
     5941 aaggggcgaa gtctatgatc aaagctattt tttttgatat tgacggaaca ttggtcacca
     6001 atcgttcaaa agcgttggaa tcaacaaaac aagcaattga atatgctcgg aaaaacggca
     6061 ttttatgcgg tgtagcaacg gggcgcagcc cagtaaagat caaagaaatc attgatgaat
     6121 tggaattaga tatgtatgtc gtgtataatg gtcaactggt ttttactgca gatcgcacga
     6181 ttatcgacca cccttttgaa caaaaagtat tggaacatat tgttgaattt gcagatgaga
     6241 accatcgaca aatcgttttt ggtgcgagaa atcggttaga tggatcaacg acgatgctat
     6301 taggacaatc gatttttatc aagcgactag tcagcttttt accgcgtaaa ttcccggtac
     6361 gtctgatgaa aaaaatcctc caggttttta gccctcaccg acaaaaggat cgttatgaaa
     6421 cgttagagat attaaaagaa ccaatttatc aatgtatatt gctcagtccg gagtcagaac
     6481 agaaaaagtt agaacatcgc tttcccgagt gtacgtttca gcgttcaaat acgtatactg
     6541 tagatatcat cccaaaaggt ggttcaaaat tactaggcat ccaagctttc gcaaatgctg
     6601 tcgaaattga aatggaagaa attatggcat tcggcgatca ttacaatgat atcgagatgc
     6661 tgaaaggtgt aggaattgga gtggccatgg ggaatgctca gatcgaagta aaacatgctg
     6721 cagactttgt gactcaatca aatgaagaag atgggatata cgaaggactg aaacacttcg
     6781 gtctgattta ttagtcaatg aaagaaggaa aaaatcagta tggaagcaga gacacctttt
     6841 caaaaagtag aaacattcca caaaactttt gatccaagaa gaccagagat acccacggct
     6901 tttacagaaa atgaagctca tacacgtgct gcgttcaaaa tagaagaact tgttgaattt
     6961 gttgcagcta cttcacctaa taaagaacaa ctgcatgaag ctgttatgct gctgcacgaa
     7021 gcattagata aagcagaaga aaaaatactt ggtaaaacac agtggggaag tgatccgctg
     7081 gttgaacaag tagatgcact gacagatatc ctttacttta cttatggttc tttttcatta
     7141 ctaggaatag tgcctgatcg aatattcgaa atcgtccatc aggcaaatat ggggaaatta
     7201 tttccagatg gaaaacctca ttatgaccct gtaacaaata aagtgttgaa acctgaaaac
     7261 tggcagatgg aatatgctcc agaacctaaa atcgcggcag aaatccaacg tcagattcaa
     7321 gaagcgattg ctaagaagaa atccgctgat ataggcatgt gcacaaatga aaaagagtga
     7381 tcagagtttc actatttttg ttatctttat acgatggaaa aacaaaagat tttcgtttaa
     7441 gttagtgaat gcatgaaaat agtatgctat aatctagaat agatgtcttt tgcacgagag
     7501 acgtattatt tggatttatg ccaagcagaa cgccatctgt tgcataaaag atgcatactg
     7561 aaaacggagg aaccataaat gggaaataat gttatcatcg gaatcgtcat tgcaatcatt
     7621 atagtcgcca ttgtcgtctt tttggttagt tacttgatga agaaaaaaaa ccaagatcga
     7681 ttggatgcct tagaaaaacg caaggaagaa ttatttgact tgccagtgat tgaagaagtc
     7741 gatgatgtta aaaaaatgca tctggttggg caaagccaaa atacctttcg tgaatggagt
     7801 caaaaatgga atgacatatc tacttcctcg ttcgctgaac tagaaagtca aattttcgaa
     7861 gtggaaaacc tcaatgaaag ttttcggttc ttaaaaggaa aaaaagcagt tgttgaagca
     7921 gaagctacaa tggaccaaat ggagaaacaa gtgacggaaa tccgtgaagg tctaaaggaa
     7981 ttgcgggaaa cggaagaacg caactcacta gctgttcagc aggcacttga cgtctatgaa
     8041 gaactgaaag aaaaagtcag agaagacgag catgaatacg gaccagctct ttttgaattg
     8101 caaaaacaga tcaaagtgat cgaaaaagaa tttacgcagt ttgtgacttt aaacacttct
     8161 ggagaccctg ttgaagcccg cgaggttttg gataaagcag aaaaacatac gtatgaagtg
     8221 gaagctctga tgaaaaaaat tccaccgctg tatgaggagc tccataccac tttccctgaa
     8281 caacttgaag aaatcagtga tacttacgag aaattgatgg aagaacaata tgtattccca
     8341 gaagaagatc ttgctgaaga tatcgcaaaa gtaagtcgaa gaattgaaaa ttcattagcc
     8401 aatcttgaaa aaacagaagt tgaaacggtc gaatttgaaa accgtgaaac agctgatttg
     8461 attgattcgt tatatgatat cttagaacgg gaaatggaag ctcagagata tgtaaaaact
     8521 aaccaatcaa cgattgcaga gtatatcaaa catacaacaa agaataaccg tcaattattg
     8581 attgagctgg atcacacatc tcaaagctat acattgaacc acaatgaaat tggccgtgta
     8641 cgaggtttcc aaaccgaagt ggaagaaatg gaacgtcaaa atgaacagat gattccacag
     8701 atccgtcaac acgaaattcc ttattcagaa gtgcgcacgt tctataaaac agtcttcaaa
     8761 gtcttagaag atatcgaaaa gcaacaagta gagatcgacg actcattaca tgaattgaga
     8821 aaaggcgaaa aagaagcgca agaaaagatc gatacattcg aattcaaatt gcgcagtttg
     8881 aaacgttttg tagaaaaaca acgtttgcct ggcttgccga atgattacct agaattcttt
     8941 tttgttgcta ctgaccgtat tgaagaacta agtgttgtct tgaataaaat tcgagtaaac
     9001 atggaagagg tcaatcgttt agttgctcta tgtgaagaag atctagaatt attagataag
     9061 aagacacatg atttagtaga tgcagcagca ttaacggagc aaatgctcca atatgcaaat
     9121 cgttatcgtc atacacacga agaagtgaga gaagcaattg ataaaagcta ctatttattc
     9181 aataaagaat atcactatca agaagcatta gacgaaatcg gtacagcatt agagcgagta
     9241 gaacctggtg ctttcaaacg catcgaagat ttttatttta atcatccaga cttagtataa
     9301 agcaaaaaag ttagtaaacc agcaagagca agacggatta ttgtcttgtt cttgtctttt
     9361 tttgtatatt tgaaaattga aacaagtgaa aatttcacct gctcttgaaa gcaccttgga
     9421 caaccgttat aatagaaaag aatttcaaaa aagaggggtt tcttatgata tattttgata
     9481 acagtgcaac aaccccaatc tttccgcaaa gcttagatgc atatgtaaaa accagtcagc
     9541 ggattattgg gaatccatca agcttgcatg atttaggcaa tcaagctaac cggttgttgc
     9601 agcaagcaag aaagcagatc gctgatttga tccatgtaga accagaagaa atctatttta
     9661 cttcaggcgg aacagaagga gataactggg tattaaaagg aacgatgatc gaaaaaagag
     9721 aatatgggaa tcatatgatc atttcaggag tcgaacatcc ggccgtcagc gagacagcag
     9781 aacaattaaa agaattagga atcgaagtaa gtatcgcccc agtggataaa cgcggatttg
     9841 tacgtgtcga cgaattgaaa gaattaataa gaaaagagac agtattagtc tctgttatgg
     9901 ctgtgaataa tgaagtagga tcgattcagc ccatccagga aatcagtgat cttttggatg
     9961 attttcctaa aattcatttc catgtagatg ctgttcaggc gattggaaaa gtaccattct
    10021 cgcaatggtt gacagaaaga gttgattttg caacattttc agctcataaa ttccatggcc
    10081 cacggggaac tggtttcatt tattggaaaa agggtcgtcg tttagcacca ttactgacag
    10141 gtggagggca agaaagaaat cagcgaagtg ggacagaaaa tgttccaggt attgtggcta
    10201 tggttaaagc tttacgttta tcattagaga taaaggaaca aaaacctgag cagacacaac
    10261 gcttaaaagt agctctaatc aatgcgttga agacgtatga gaaagtgacg attttttcag
    10321 aaggaactga ctatgcaccg catattttat gttttgctct aaaaggaatt cgcggcgaag
    10381 ttctcgtcca tgccttagaa gaaaaacaaa tatttgtttc tactactagt gcctgctcct
    10441 cacgtaaaca tatggcaagc agtacattgc acgcaatgca tgtaccaaat gatctggcta
    10501 catctgctgt tcgaatcagc ttagatgaaa acaattcgct tgcagaagtc gagcaattta
    10561 tgattatttt caagcagctt tataagaaat tttctgcaat caattaaaag aggagtgttc
    10621 ttgtgaaata cagtgaaatt atggtccgtt atggggaact ttcgacaaaa ggaaagaatc
    10681 gaaaaagctt tatcatgcaa ctagcacaaa atgtcagaca agctttgaaa gactttccag
    10741 aaatcaaaat ccatgctgat cgggaccgga tgcatctttt attgaatggc gcagacgggc
    10801 agctagttat tccaaaacta gcaaaaatat ttgggatcca aaatttctct ccaagtattc
    10861 gtgtagaaaa agatgtcgaa gttttgaaac aagctgttca agacatcatg aaagaaattt
    10921 atactgggaa agaaacattt aaaattatcg ctaaaagaag cgatcaccaa tttgaattga
    10981 caagtaatga attgaatcaa acattaggta atgctgtttt tgatattttc ccgcatatcc
    11041 aagttcaaat gcgtcaacca gatattccat tacgtgtaga gattcggcgt gatggcgctt
    11101 atctatcgta tgaaacgatc aagggagctg gaggattgcc cgtaggaaca agcggaaaag
    11161 gaatgcttat gctttctggg gggattgatt ctcctgtagc agggtacttt gccatgaagc
    11221 ggggagtgga aattgaagct gttcattttg ctagtccgcc gtatacaagt gaacaagcac
    11281 tgcaaaaagc aaaagatcta acagccaaac tagcacctta tgtgggaacg atccatttta
    11341 tcgaagtgcc atttaccgag attcaagaag aaatcaaaaa gtcagtgcca caaggatatt
    11401 ggatgacaat tactcgtcga atgatgttgc gtttgaccga tgaaattcgc cgtattcgtc
    11461 atggtttagt cattttgaat ggtgaatcat taggtcaagt ggcttcacaa actttgcaaa
    11521 gtatggtggc tatcaatgaa gtaacgaata cgccaatcat tcggcctgta gcgacaatgg
    11581 ataaacttga aatcattgaa gtagcagaac agatcgatac atttaatctt tctatccagc
    11641 cttttgaaga ttgctgtacg atttttgctc ctccacagcc aaaaacacgc cctcaactgg
    11701 aaaaggtcca tcaatatgaa gagcgtttag caatagatga aatgatccaa cgagcactag
    11761 ctggcttgaa gatggaagag atacaagcag aatcgtctaa tgaaaaaact gaagaatttt
    11821 cagaattgct ataagaggtt atgaaaatag tgttttgacc agagtattag agaaacaaaa
    11881 cgaaaaaata gctccatgta ttttaccgtt tttgaactaa tgtcgaagat tagctgattg
    11941 aataccattt atcaagaagt tatggaaaag ccggttcttt tttactaact gaaaaataaa
    12001 attttattta gagatcaagc tacagttgat aaatgatata aaaaagagaa tttcccatga
    12061 aatagcgagg ttgtgacaga agtgggcagc ttcaagaaat aagaaggaat ttacgaaaat
    12121 tgcttttcaa atttttgtga aatttcggct tatttttcga agaagttact tctggaacac
    12181 cgtgtatcag aggttgcgaa aaagctgccc tgcatcaagt aataagaaca gccaaacaaa
    12241 aatagttcct catattttac gtttggttga gcttattacc gcagatgcaa gcttttgaac
    12301 accgttttat ttgtctcaca cccttttcct tcctacttgt aaccttgctc ccgtgttaga
    12361 aacatgttac actaaatatg tgaaattatt aacaaggagc gtcgttatgc gagaaaaaac
    12421 agatacactg ccaaaagcaa ctgcgaaaag attaccttta tatttacgct acttgaagat
    12481 gctggatgac tcaggtataa gtagaatcaa atcaaatgag ttcagcgaaa tcacccaaat
    12541 tccttctgca acgatccgca gagacttctc gcaattaggc gagctaggca gaagcggata
    12601 tggctatgat gtcccttttc ttatcgatgt attcaataat atccttaata ctaaagaaga
    12661 aaaacgaatc gcattagtag gatatggaaa tcttggcaaa gcattgaaac acaacaattt
    12721 tagaagaaat gaaaatctaa atatcgtgtg cgtctttgat aatgatccag cactgatcaa
    12781 tcgagtaatt gatggagaaa tgatctatcc gattgatcgt ttcgcggaga tagccaaagc
    12841 aaaaaatgtg acagtagcaa tctctacggt accaagtaaa tattcacaat ctgctattga
    12901 tgaaattgtc aaaggaaatg taaccgctat acttaatttt gcgcctgaca gagtaactgt
    12961 cccagcttat gtcaatgttc aatacattga tttgacaacc gagttgcaga cgcttattta
    13021 ctttgatgag aattactcag aagttttttc ttaggaaaat ttgagtaggc ttattgatct
    13081 tgcgagaact cgtcgtaatt ctttcaaaaa ttttttagta ctaaatgaag tggttttttc
    13141 acgaccactt gttgactaaa aaaaaaaacc attgtagaat gaagcataac gctgaacaag
    13201 aggagtaact ggcacattca ttcttagaga gagaactatc tgctgaaagg ttctcaatga
    13261 caaccagtga aggtagcttg ggagtttctg tcttgaatgg agtagagata gacgagtcgt
    13321 gatcgttaac tcacttgaga ggcaataatg attgattatt gcaatttagg tggtaccgcg
    13381 taaatcatac gtcctagaat acgaaagtat tttaggacgt tttttagttt aaaggaggaa
    13441 aacagcatga cggaagaaaa taacctatca acaaaatata atccgcaaga agttgaagct
    13501 ggacgttatc agcattggtt agaacaagat ttgtttaaac cgagcggaga taaaaaagca
    13561 aaaccttatt caatcgtaat cccgccccca aatgttactg gaaaacttca tttagggcat
    13621 gcttgggata cgaccttgca agatatgctg attcgtcaaa agagaatgca aggatatgat
    13681 actttatggc tgcctggtat ggaccatgca ggaatcgcga cacaagcaaa agtagaagcg
    13741 aagcttagag agcaagggat ttctcgttat gatctaggtc gtgaaaagtt catcgatcaa
    13801 gtgtgggaat ggaaagaaga gtatgcgagc cacatccgcg aacagtgggc taaaatgggc
    13861 ttatctttag attacagtag ggaacgtttt acattagatg atggattatc tgaagcagta
    13921 cgtaaagttt ttgttacctt atacgaaaaa ggtttgattt atcgtggtga atatatcatc
    13981 aactgggatc ctcaagcacg aacagctcta tctgatatcg aagttattca taaagatatc
    14041 gaaggcgcct tttatcatat gagctatgaa ctagcagatg gatcaggcgt agtagaaatt
    14101 gcgacaaccc gtccagaaac gatgttggga gatacggcga ttgctgttca tccagaagac
    14161 gagcgttatc aagcgctcat cggcaaaaaa gtgattctac ctttagtcaa taaacaaatc
    14221 ccaatcattg cagatgaata tgtagatatg gaattcggga caggtgtagt aaaaatcact
    14281 ccagcacatg atccaaacga ctttgaggta ggtaatcgtc atgatcttcc acgcgtaaat
    14341 gttatggatg atgatggtac gatgaatgaa ctagcaggaa aatatgctgg aatggaacgt
    14401 tttgctgctc gtaaagcaat cgtgcaagat ctgaaagaaa tcggtcgatt gattaaaatc
    14461 gatacgatga tccacagtgt gggtcattcc gagcggacag gtgtcgttgt tgaacctcgg
    14521 ctgtctactc aatggtttgt aaaaatggcg ccgttagcga aaaaagccat tgataaccaa
    14581 gaaacagatc aagcagtgga attcttccct ccaagattca atcaaacgtt tttacgttgg
    14641 atggaaaatg tccatgattg ggtaatctca cgacaattat ggtggggaca tcaaattcct
    14701 gcatggtatc acaaagaaac aggtgaaatg tatgtaggga tggaagcacc agcggatagt
    14761 gaaaactggg tacaagatcc tgatgtttta gacacttggt ttagttcagc tttgtggcct
    14821 ttctcaacaa tgggctggcc agatacggaa agcgaagatt ataagcgata cttccctact
    14881 agcactttag taaccggtta tgacatcatt ttcttctggg taagcagaat gattttccaa
    14941 agcttggaat ttactggcga acgtccattt gagaatgtct tgattcatgg attgattcgt
    15001 gacgaacaag ggcggaagat gagtaaatca ttaggtaatg gaatcgatcc gatggaagta
    15061 atcgaaaagt atggagcaga tgctctccgc tggttcttat cgaatggttc tgcaccagga
    15121 caagatgtcc gcttcagcta tgaaaaaatg gatgcttctt ggaactttat caacaaaatc
    15181 tggaatgctt cacgtttcgt tatcatgaat atcgaaggaa tgaccgtaga agagatcgat
    15241 ttatctggag aaaaatcagt ggctgaccgg tggatcctta ctcgtttgaa tgaaacgatc
    15301 gaacgagtaa ctgagctatt tgatcgtttt gaatttggtg aagcaggtcg acaactgtat
    15361 aactttatct gggatgattt ttgtgactgg tacatcgaaa tgagtaaaga agtactttat
    15421 ggagatgatg ctgtttcaaa acaaaccacc cgtagcatct tagtccatac acttgatcag
    15481 atcctacgtt tattgcatcc aatcatgcca ttcgttacag aagaaatatg ggaacatatt
    15541 cctcatcagg gaaattctct agtagtggca gaatatcctg ttgtacgtcc agagtttgat
    15601 gatgaaacag cttctaaagg gatggaagta ttgaaagaat tgattcgagc cgttcgaaat
    15661 attcgttcag aagtgaatac accattgtct aaaccaatta cgttgctaat taaaacaaac
    15721 gatgctaaaa tcgatcaatt tttagttgaa aatacaagct atatcgaacg cttctgtaat
    15781 cccgaagagt tgacgatatc aagtgagatc actgcgccag atctagcgat gtcagctgtt
    15841 ctgacaggtg cagaaatctt cttgccgtta gcaggattga tcaatattga agaagaaatc
    15901 aaacgattag aaaaagaact ggaaaagtgg acaagcgaag taaaacgtgt ccaaggaaaa
    15961 ctttctaatg aacgttttgt ttctaacgcg ccggaagaag tagtagaggc agagcgtgca
    16021 aaagaaaaag attatttaga gaagcaaacg gctgtcaaag aacgaatcga aagtttgcgt
    16081 actattcaat aagaatagaa aaagagagtg tgaaatcagc tagctattac taaaagctag
    16141 ctgattgaac atcgttacag gaaagagttt gagcctcact cttagcttcg attcataagg
    16201 agatgtgaca taaattttgt cgcatctctt ttttagtcta ctcttattat gtaggagaag
    16261 gagggaggtg gatcatgtat caagagtcaa taaagtagtt gataaaatcg ttcctctctc
    16321 tgtttctttt ctctttgtca tacttttatt tttcttatgt gttctatttg ttataataaa
    16381 agagaaatgg gggaattgtt gatgacgatt gaagaagcaa tagaatggat ccatagtcga
    16441 ttaccatttg gttcacgtcc tggccttgac cgagtcgaag ctttattaga agtggtaggg
    16501 catccagaga gaaaagtaaa aacgatccat atcgctggaa caaacggaaa aggttctact
    16561 gtagcttatt tgagaagcct attagaagag gctgggctga cagtaggtac atttacttca
    16621 ccttatatcg aaacgttcaa tgaacggatc gcaatcaatg gcaaaagcat tccagacaat
    16681 gatttgatcc agcttgtaaa aaaatatcag ccactgatca aacaacttga tcaatttgaa
    16741 gcagtagctg gtattactga attcgagaca ttaacagcaa tggcatttga ttattttttg
    16801 atgaagaaag tggacgtagc gattatcgaa gttggcttag gcggcttatt ggattctacc
    16861 aatgtagctg taccaatgct gacgggaata acaacgattg gacttgatca taccgaaata
    16921 cttggagata caattgaaga aatcgctgca caaaaagctg gaatcatcaa acaaggcgtt
    16981 ccagtagtaa caggaaatat tgccccagaa gcttttactg tcatccaaca aacagctaaa
    17041 gcaaaaaatg caccgcttta tgtatacggg gaaaattata aaataaacta tctgcatcct
    17101 gatgagatgt ggggagaagt atttgaattt tttaatgaaa taggaaagat ccctcaatta
    17161 accactccgc ttttagggca acatcaagct gaaaatgcag gagtagccat cgaattgtat
    17221 tttgtttact gtcaattgga aaagctgcct ttccgagaaa aagatgtttt gaagggattg
    17281 aagaaatctc gatggccagg aagaatggag cgtttgagta acgagccatt agttgtttta
    17341 gatggtgccc ataatacgca tgcaatgaac cggcttgttg agaatttgaa aaaagaattc
    17401 aaaggatatc aaatcaacat tttgttttcc gccttacgaa ctaaaaatgt tagagaaatg
    17461 ctagaacgat tgcagcaagt accaaatgtc catatttatt tgacgacctt tgaacatcca
    17521 aaagccatcg aattaagtga agtatcagat ttagcaagtg agagagtatc aatcgtttca
    17581 ttgtggcaat tcggattagc agatatattg gaaaagatga caaatgaaga cgtattagtt
    17641 gtgaccggtt cactttattt catttcagaa gttcgccatt tattaataca attaggagga
    17701 gatcatgaag tataatgcag tgatttttga catggatggt ttgctgttcg acacagagtt
    17761 agtgtattac gaagccacac aagtagtagc agacaagatg ggttttcctt atgataaaga
    17821 cctgtattta aaattcttag gtgtttcaga tgaagaagta tgggcgaatt atcatatgat
    17881 tttctcggaa tttggcaaaa caagtgtaca aagattcata gatgattcat accaggaaac
    17941 gcttgaacgt ttttcgcaag gagcggtaca aatgaagccc ggtgtgttgg aactcctctc
    18001 ttttttagaa gaacatcaga ttcccaaagt tgtcgcttcc agtaaccaac gagcagtcat
    18061 tgaactttta ttgaagaaga acaatctgtt tgaacgattt gagacgattg tttctgcaga
    18121 aaatgttcaa cgagcaaaac cagacccaga aattttcttg ttagctaatc agaagctagg
    18181 tacagcgaag aaagaaacat tgattttaga agattcacaa aatggtattt tagcagcttc
    18241 tgcggctgag atcccggtag tcatggtacc agatctgctt ccaccatccc aagaattgat
    18301 caaaaaaaca gctggggttg tttcttcttt acatgaaatc cctgcattgt taaaataaaa
    18361 atccatctct tttcgtatct tattttagat aagatagaaa ggagatgttt ttttgggaaa
    18421 acgattgatc aaagaagtac ctactagctc tttaccaagg gaacgtatgg aaatttatgg
    18481 cgcggaagct ttatcggatc aggagctttt ggcaatctta ctgcgtaccg gtcaacaccc
    18541 ttatagtgtg atgtcgattg ctggaaatct gttaaaaacg tttggaggac tggcctcttt
    18601 acgacaggct actttgcatg agttagaaga gattcgaggg ataggacgcg tgaaagcaat
    18661 cgaaatcaaa gccttgatcg aattaggtcg acgaattcag acggatcatg aaagagcggc
    18721 tccaccggtt cgtaccagct acgaattggc ccagcaattg attctggaaa tgaaagatca
    18781 caaacaagaa catttggttt gtatttattt ggacacgaag aatcaagtga tcttaaaaaa
    18841 aacagtgttc atcggttcgc tgaatcagtc agtcgctcat cctagagaaa ttttccatta
    18901 tgctgtacgt tattgtgcag caaggatcgt tttagcgcat aatcatcctt ctggtaatgt
    18961 tattccatcg cagcaggata tgaattttac caaaaggata caaaagtgtg gagaaatgat
    19021 ggggatcact gtactggacc acttgatcat cggacgcaaa cgatatttta gtttgagaga
    19081 agaaggaatg atggaagaga agtaagttgc tttcttgcaa aaaaaatgaa gcaagtgtac
    19141 aattatattg taattttgtt tgggaataga agttgaaaca tctgttgcac ctctatcgta
    19201 cacgagcaat gttacaattt aaattagtgc ttttggcacg aggaggatat tattatggaa
    19261 aacggaacag taaaatggtt caacgctgaa aaaggatttg gatttatctc acgtgaagat
    19321 ggaagcgacg tattcgttca cttctcagct atccaaggtg acggattcaa aacattagaa
    19381 gaaggtcaag cagtgacttt cgacgttgaa gaatcagacc gcggcccaca agctgcaaac
    19441 gttgtaaaag cttaatttta tctgtaaatc aaattgatgg tagacatcaa tttttacgag
    19501 agaacaaagc gagtaacaaa aatacctgcc acaagagaca atttctcttg tggcaggt
//
LOCUS       DACDAF010000052        18880 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.052, whole genome shotgun sequence.
ACCESSION   DACDAF010000052 DACDAF010000000
VERSION     DACDAF010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18880
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.052"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..435
                     /locus_tag="IVZ69_001728"
     CDS             <1..435
                     /locus_tag="IVZ69_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HAP8183810.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            complement(759..842)
                     /locus_tag="IVZ69_001729"
     tRNA            complement(759..842)
                     /locus_tag="IVZ69_001729"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(806..808),aa:Leu,seq:cag)
     gene            1370..1870
                     /locus_tag="IVZ69_001730"
     CDS             1370..1870
                     /locus_tag="IVZ69_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8183811.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(2060..2404)
                     /locus_tag="IVZ69_001731"
     CDS             complement(2060..2404)
                     /locus_tag="IVZ69_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HAP8183812.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2558..3478)
                     /locus_tag="IVZ69_001732"
     CDS             complement(2558..3478)
                     /locus_tag="IVZ69_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP8183813.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3665..4156
                     /locus_tag="IVZ69_001733"
     CDS             3665..4156
                     /locus_tag="IVZ69_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HAP8183814.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(4180..6555)
                     /locus_tag="IVZ69_001734"
     CDS             complement(4180..6555)
                     /locus_tag="IVZ69_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HAP8183815.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6881..7507
                     /locus_tag="IVZ69_001735"
     CDS             6881..7507
                     /locus_tag="IVZ69_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP8183816.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7530..8234
                     /locus_tag="IVZ69_001736"
     CDS             7530..8234
                     /locus_tag="IVZ69_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP8183817.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            8426..9259
                     /locus_tag="IVZ69_001737"
     CDS             8426..9259
                     /locus_tag="IVZ69_001737"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HAP8183818.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            9456..11384
                     /locus_tag="IVZ69_001738"
     CDS             9456..11384
                     /locus_tag="IVZ69_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HAP8183819.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            11522..11977
                     /locus_tag="IVZ69_001739"
     CDS             11522..11977
                     /locus_tag="IVZ69_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HAP8183820.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            12447..12716
                     /locus_tag="IVZ69_001740"
     CDS             12447..12716
                     /locus_tag="IVZ69_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183821.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            13116..13370
                     /locus_tag="IVZ69_001741"
     CDS             13116..13370
                     /locus_tag="IVZ69_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HAP8183822.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(13459..14505)
                     /gene="holA"
                     /locus_tag="IVZ69_001742"
     CDS             complement(13459..14505)
                     /gene="holA"
                     /locus_tag="IVZ69_001742"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HAP8183823.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(14543..16816)
                     /locus_tag="IVZ69_001743"
     CDS             complement(14543..16816)
                     /locus_tag="IVZ69_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HAP8183824.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            complement(16809..17348)
                     /locus_tag="IVZ69_001744"
     CDS             complement(16809..17348)
                     /locus_tag="IVZ69_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HAP8183825.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            complement(17484..17702)
                     /locus_tag="IVZ69_001745"
     CDS             complement(17484..17702)
                     /locus_tag="IVZ69_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HAP8183826.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            complement(17699..17944)
                     /locus_tag="IVZ69_001746"
     CDS             complement(17699..17944)
                     /locus_tag="IVZ69_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP8183827.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            complement(18060..18788)
                     /locus_tag="IVZ69_001747"
     CDS             complement(18060..18788)
                     /locus_tag="IVZ69_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComEA"
                     /protein_id="HAP8183828.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
BASE COUNT         5798 a         3654 c         3316 g         6112 t
ORIGIN      
        1 tactcaggac aacaattaac aatcccaaca gaaggctctg cacaagcagc tgctgaacct
       61 caagcagccg ttcaagaagc accagtccaa gctgaacctg ttcaagctga acaacctgtt
      121 gtacaagaaa cggttcaaac ggaaacacaa gcagcgcctg ttgctgaaac acaacctgct
      181 cctgctgtaa cagaaactgc tgctactcca gcaagtacaa gctctgcaaa agaatggatc
      241 gcacaaaaag aatcaagcgg ttcttacaca gcaacgaacg gacgttacat cggccgttac
      301 caattagatt cttcttactt aaatggtgac tactctgctg caaaccaaga aagagtagca
      361 gaacaatatg ttacttcacg ttatggttct tgggaagcgg cgaaagcatt ctgggaagca
      421 aacggttggt actaagattc attatttgaa cgtttaaaca cattcaaaat atagtaagag
      481 gtcatgcgat ttattctttc gcatgacctc tttttgagtt taagtttagt ctttattcct
      541 taactatcgt ttgccagtat ttcttgtatc agaatctata aatctactat ttgaatcaat
      601 ctattaggtt ttaaactgtc ccaccttcac acaaattttt tttgatttat ttgaatctgg
      661 ttccgttgtt taaaattttt cctatattct tttagataat atgttatttt ctttctcatc
      721 gctccaggtg taccttctct ttataaaaaa acaaattatg cggctaagaa gactcgaact
      781 tccacgaggt caccctcact agcgcctgaa gctagcgcgt ctgccaattc cgccatagcc
      841 gcatcacatc ttttagttta ggattacatg tgttttttgt caagaacata tttttgttct
      901 ttttcatttc tgtacgccct cccttatgcc atctacacaa ataattcatc cgagcaactc
      961 catcatctat tgagggttgg tgaaaaaatc tgttttatcc atatgatcga tttcaatgtt
     1021 aaacgaacga ctctgggatt agtaactatt ttattttttt cttcatttct tttttcctct
     1081 ttttctcgat tcagctatct tctttcattt ggatattgat tatttcttct gttgattact
     1141 atccttctgg aattctagac gctgaagtaa ttcacgtttt ctttcttcta gagatcataa
     1201 gtaacgaatg aacgaacttc aaataatttt tttattgtaa ttcatatttg tattgttcga
     1261 tgattcttaa tacgatatga cacaataaat aaaaataggc atggctattt acaacaatag
     1321 tgctatagta gaaaacaaat gaataaggtt acttaaagag gtgaatacga tgaaactgat
     1381 caaactatgg gaagcagatt taaagaaagc ttatcagcta caaactagct ttggaccaaa
     1441 tgagagtgga tttatcaaca atgcttatgg ctatacattt gctgaatttt tagattatgt
     1501 aaaaaaatgc gaaaaaacgt ctttaggaat cgatcttcct gagagttacg ttcccgcaac
     1561 cgtctttatt ttagaaagtg atgaacatga gtatgtagga atttttaatt tgcgccataa
     1621 actgaacgaa acattaagaa acggcgctgg ccatattggt tacggcatct cccctaatta
     1681 tcgtaaaaaa ggatatgcca cacaaggatt agcattagta ctacaagagg caaaaaaaat
     1741 cggcattgat gaggcacttt tgtctgtaaa taaaaaaaat cttggcagtc ttaaagcaca
     1801 acaaaaaaat ggggctgcga tttatcgtga agatgagaaa gaatactata cgaaaatcaa
     1861 actgatgtaa aaaagaagga ttccaaaagg aaagggattt gaatgtcctt tatcaataga
     1921 acacatttat ttaattaact tataatatag cagacaaaat tttataaaca aagaaacctt
     1981 ttatctcttt tcttctagaa aggataaaag gcttttttgt ttttcctatt tgcttctcat
     2041 agctagtcag ccaagatttc tatcgtatcc ccaacgcaat ccgtgcataa cggctcatct
     2101 tatctgtcgt ccatgctgga taccagacta gtttgacttc tgctttcgtt acttctggca
     2161 cttcttttaa tgcgtcatgg atagattctg ttaaaatatc tgctaatgga cagcccatag
     2221 ttgttagagt catcttaatg actgtttctc cattttcagg attgaattct atatcataaa
     2281 tcaagcctaa attgacgatg tcgattccta attcaggatc aatcaccatt tccaaggcag
     2341 caagaatacg ttctttgatt agttctattt cttgtccaga ccgttcttgg tttgcttcgc
     2401 tcatcgtacg acactcctta acacgatttt tatttatcat actctttttt tagctgcttg
     2461 taaatgagaa tttagaagta agattctcgt ttaaatttat aaaaatgttc ttattagatg
     2521 taatagatta aatttattct aaaataaacc tgattcctca ttttttttgt gaacgatttt
     2581 ttatttctgg caatacgcca gttgttcgat acattttttg ttcgttttca tttgcaaacc
     2641 ggccaaatac tgaatgagtt ggtaaaatat tgataaatgc atcgtcgtcg atttcatgaa
     2701 cgatctgatc aagatcatac atttcgtagc gggtgatgac catcatgatc atgttccctt
     2761 gtttttttga atagccaccg acagacggca gtaatgtcat tccacgtacc atccgttttg
     2821 ctagttcttc tgttacctct tctggcttga cggtaacgat cattgctgtt actttttgat
     2881 gactcgtgtg gatggcatca attacttgag tcattgcata aatggaaata atcgtataca
     2941 aggcactttc ccagttaaag aagaagcctg cgatgactac aatgatacca tttagaatca
     3001 gcatgtagtt tccgactgtt tttccagttg tttgtgaaag tacaagagag atgatatcca
     3061 tcccaccagt tgtaaagccc atttttaaag ataatcctac gccaagacct aataaaacac
     3121 cgcctactag ggcattcatc aaaatattat cagtgatctg tccgactgga agcagcatcg
     3181 tcatcaccga tacacataca acattcacaa aactaaggat cgttgctcgt tttcctactt
     3241 tgagaaaccc taatacaaac acagggatat tcaaaagaaa aataaatgtt cctgtgtcta
     3301 tcttgatatg aaaccattca tataaaagcg aggaaatgat ttgagcgatc ccattcatcc
     3361 ctgcagaaaa gacattggct ggaatcaaaa aataatttaa agcgaccgca gcggtcaatc
     3421 cggttatcaa aataaccact attttcttta atctttcatt tttatgatac gcagtcataa
     3481 ttttactcac aagcacctct cccctacttt ggtattccaa atgtaagaat aacagtttat
     3541 ctattaaaat aaaatacttc gaactcaaat gagaagaatt ttagcaaaca ggtaagaatc
     3601 tgccctaatc ctatgataag atagatgtat ggtaaatatt tatatgtata tcaggagggt
     3661 tcctatggca aaagatgcta gcttcgacat tgtatcagaa gtcaatacag aagaagtaaa
     3721 aaatgcgatt cagcaaacaa caaaagaatt gtccaatcgc tttgacttca aggattctac
     3781 agtagaaatc aaattagaga acagcaatct agttgtattg agcgatgatg atttcaaaat
     3841 cgaacagatc aaagatgtat tatttggtaa gctgatcaaa agaaatgtgc caatcaaaaa
     3901 tatccatttt tccgaatcag aacacgctct aggtggcaaa gctcgacaaa ctgccgattt
     3961 ggtcaacgga atcgatcgtg aaaacgcgaa gaaaatcact acagctatca aaaatgaaaa
     4021 actgaaagta aaagcacaaa tccaagaaga tcagattaga gtgacaggta agaaccgtga
     4081 tgatctacaa gctgtgattg ctttattacg taaacttgac ttaccaatcg agttgcaatt
     4141 cactaactat cgttaatcaa aaaacgaggc tgacgtctgt cattcctcgt ttttttgatt
     4201 tactgcttct tttgataacc aaaaacgctg tattccttct tccaattccc caacacttcg
     4261 tacttctctt gctgtttgcc aatgttgtgg gaataaacgt cgataagaaa aactagaaaa
     4321 tcgttgatct gccaatacaa cgattccttg atccgccatg ccacgaatca ctcgaccacc
     4381 agcttgcaag actttgttca ttccaggaag ctgataagcg taagcaaatc caaggtgttc
     4441 cttctcatca taatatgatt tgatcagttc ctgctcatga ttcatctgcg gcaaacctac
     4501 acctacgatc atactgccga tcaatcggtc ccctctcaaa tcgattcctt ctgaaaaaat
     4561 cccgccaagt acgcaaaatc caatcaatgt ttcagcggga tttgtttgaa attttgttaa
     4621 aaatcgttcg cgttcttcct cattcatgtc cgtttcttgg attagcacat tgctgtcggg
     4681 atattgctgt ctgaatgctt ccaccgcaag atctaaatat tgataagaag gaaagaaaac
     4741 gaaataattc ccgacctttc catcagcaaa agcatgaatc gtctctacta attttgccag
     4801 actgtgttcc ctttttcgat aagtcgtctc taggtaattt gcgatgaaaa cttgctggtt
     4861 tccttctggg aaaggactcg gcagtttgta agccagactt ttttgtcccc ccagtgtttc
     4921 ctgataataa gagagtggtg aaaaactagc agaaaaaaga atactgcttt ttcctttatc
     4981 caacgactgc tcaagaaaca agcttggatc aatacaaaac tcttttacta tcagatcgcg
     5041 atacgttttt tcgactgttg tttcgtagtg atcatcataa aattcactga ccttcaaaaa
     5101 atgaagcaaa tcaaaataat aaggaagcaa ttgttcttgt gatgggtgct caggaaattc
     5161 tgccagccat tctttaattt tttcgcttaa ttgataacct gcctttacta aagattcagc
     5221 cggtgctttt tgatgatgat aatcccaatg atcttctttt gctatttctc ggatcgaatc
     5281 aaattctttt aatagtttgt tgaaacggcg atgaagtttt ttgaattcct ttggtatagc
     5341 ttccttactt cgtttcgttt tttcataaga tagttctgcc gaatacatct ctcgggaacg
     5401 attcaccaaa ttatgtgctt cgtcaatcaa aaacagatag tcctcgtttt tttcatcttc
     5461 aaaaaaacgt cttaaataaa cagttggatc aaataaataa ttgtaatccc caatgattac
     5521 gtcacaccag atactgacat ctaatgatag ttcgaaagga caaagtgtat gctttcttgc
     5581 ataagtttcg atgacttcac gagtgatctg attctcatga ttcaaaagat cccataaacc
     5641 ttcattaatc cgattgtaat aaccattggc atatgggcac tgatctggat tacaggtcgt
     5701 ctcatctaaa aagcagatct tgtctttcgc cgtcaaagtg acacttttta cttcagctcc
     5761 tgtatctttt aatgctgtca tagcatcttc agctacttgt ctagttattg ttttagccgt
     5821 tagataaaag atcttttctc cctcttcttc ccctacagct ttcaaagcgg ggaataacgt
     5881 agagattgtt tttcctgttc cggtaggtgc ttctacaaac aatttctgtt tcgtacggat
     5941 cgttttataa gcagctaccg ctagttcacg ctgacctttc ctatactcat catgggggaa
     6001 tttcaaagcc atcaaagagg cattgcgtac agtgcgccag ttttcttgaa aaacaagcca
     6061 ttctttataa tcttcagtca gctttttaaa aaaagtttct aactgctctc ttgtctgatg
     6121 ttcaaccttt ctcgtgatca cttcttctgc cgtctggaag taagtcaatt gcagatttat
     6181 ttcttgtaaa tcatgttctt gactatagat ataggcatac acccttgctt gatgaaagaa
     6241 aagttccact tgttctggtt ctaaatcttc aaatcgtggt tcggaggttt tgatttcatc
     6301 tatataataa ataccgtctc ttttgaaaat accgtctgca cggccttcaa cgatcaggta
     6361 atattcatct aattgaactg ttgtttttaa aaagacttct ttttcatagt tttctcccgc
     6421 atctttttgg agcttgcggt ggattctcgc tccttctaat gcagtatggt tacttttttt
     6481 acgattgtcg atacttccac gtcgcaaaat aaattctact aagtgccgca cagatatttt
     6541 tgactgtttg atcatttcca ccacctcttt ctctctaaga ttacctgaaa aaacctagtt
     6601 tagcaaaaag agctctcttt ccaaacataa aaaaacaccc tgctgattag gcagggatat
     6661 aggatataga atttggattt ttggatgaat ctaatgtaac aaggacatat taaaatgcta
     6721 tgaaaactta ctttccttct ctttagaata tccaaatact tttcatatag tctgataatt
     6781 cagataagta aagagaaata agtacctgtt tttgtttcct agcaatgaat gcgttatact
     6841 aatggatgaa agaagttttg gctatcaagg aggaatgcac atgcatatcg aaagattaaa
     6901 aacaggaatg attgaagaaa actgttattt ggtctacaac gaagaagcac ttttgatcat
     6961 tgaccctgga gaagatgcgg aacgaatcaa acaagaaatc aaaaaaacaa accaacagcc
     7021 ggtagcgatt ttgcttaccc atactcacta cgatcatatc ggtgcagtgg aacctttacg
     7081 cgcgtattat caaatcccag tttatgtcag cccactagag caaaaatggc taggtgatcc
     7141 gattttgaat ctttctggac tcggtagaca tgatgatatt gctgatgtta ttgtctcgcc
     7201 tgcagaatat gaatttgaaa tgaaaactta tactttagga aacatgtctt ttcgcgtcgt
     7261 ccctacccca gggcattcta taggaagcgt cagctttatt tttgatgatt ttgtcgtttc
     7321 tggcgacgcc ctgtttagag gaagtatcgg tagaaccgat ctgtatacag ggaatttaga
     7381 acaattactt catagtattc ggacccagct gtttgtatta cctgatgaat ttgcagtcta
     7441 tccaggacat ggcgatgcaa cgacgattga acaggaaaaa aggacaaatc cttttttcaa
     7501 tcgttaaaac gacttaggag gagaataaaa tgacagaaac tacactttat atcgtacgac
     7561 acggaaaaac gatgttcaat acaattgaac gagtacaagg ctggtgtgat acacccctca
     7621 caaagcaagg acaagaaggc attcattatt taggtcgcgg gttaaaaaat gtcgactttt
     7681 catttgctta ttctagtgac agtggtcgtg caatcgaaac tgcccgtatt attctaggag
     7741 aacattctaa gggaaaagaa attccttatt ttattgaaaa aaggattaga gaatggtgtt
     7801 tcgggtctct tgaaggtgga tatgacatgg aaatgtgggg tgtgatccct cgtgtattga
     7861 attttaaaac atatgatgaa atgtttacca cagaagtttc ttttgaacaa attgctaatg
     7921 ctgtatacaa cttagatacc gctgggtggg cggaaactta tgaaacattg cgagaccgtg
     7981 tatggacagg atttgaagat atcgcccatc actgcgaaaa aaatggtggt ggaaatgttt
     8041 tagtcgtatc tcatggtttg acgatcgcct ttttgcttaa tctgatcgat cctaaacagc
     8101 ctgttcgtgc tgggctttta aatggcagcg taacaaaggt cacttatgca aacggtcgat
     8161 tttctatcca cggcatcaat gatacgtctt atatcgataa cgggaaaaca catagtcgcg
     8221 actcgtttct ataatgggga tattttaatt tttaccagag aatcataaaa ggcaaagtct
     8281 gaacgagggc tttgtcttct tttttctctt cgtgtactta tctgctttat ttctcaagtt
     8341 tttcttaata ttaaaaaaca gattgggttt ctcaaaaaat aacggtatac tataagatgt
     8401 atcttaattg ggaaggaagg aatttatgtt ttttgcaaat attatcaaag cagtgattct
     8461 cggtattatt gaaggaataa cggaatggct gcccatcagt agtactggtc atttgatcct
     8521 agcagatgaa ttcatcaaac tggatgccag ttcacaattt atgtcgatgt tcaatgtcgt
     8581 tatccaatta ggggcgatct tggctgtcgt cgttctttat tttcacaagt taaacccatt
     8641 ttctccaagt aaatcaacgg tagaaaaaaa agatacgtgg acactttggt ttaaagtgat
     8701 cgttgcttgc ataccagcca tcatcattgg tttgcctttg gatgattggt tagaagcaaa
     8761 tttccacaag ttcttaccag ttgccattgt tttgatcgtt tacggtattg cctttattat
     8821 tgtcgaaaaa cgcaacaaaa acaaaacacc tcgttggact tctctgaatg actttacgta
     8881 ccaagcagct cttcttgttg ggttattcca agtcttggca cttgttcccg gaacatcccg
     8941 ttctggcgca acgatcctag gatctatctt gattggtgct tcgcgttttg tcgctacaga
     9001 gttttcattt ttcttaggga ttcctgtcat gtttggcgca agcggcttga agatcgtcaa
     9061 atatttagct gaagggaatt cattcaaaat ggaagaaact gttgttcttc ttgtaggaac
     9121 attcgtatct tttgtggttt ccgtcttagc tatcaaattc ttactaagct atttgaagaa
     9181 aaacgacttt accgcttttg gctggtatcg tattatcctt ggtatcattt tgattggtta
     9241 ttggtttatt gcaatgtaga aaaaaccaga acacttctct tatttgagaa atgttctggt
     9301 tttttatttt ctttaataat aatcattata aataataaaa acaacatcaa gcttaatcac
     9361 caaatgataa ccattatcgt tctcatttag ctgttattat tatcaattac atttttatta
     9421 tgctatcctt gttttgacaa ggaggtctaa taacgatgac taatcagaaa aaagcttttg
     9481 cagcaacaat cggctgcctt ttatttatga tcttcggttt tatcttcgac cgattctctc
     9541 ttaccatcac cccacttttt tatatcagtg ccattatcat cggtggatat aaacaaacat
     9601 cggaaggctt gaaagaattg tggaatgatc ggacactgaa tgtggattta ttgatggctt
     9661 tagctgctat tggtgcctgt ttgatcggta attactttga aggagcaatg ttgacattca
     9721 tcttttgttt aagcggtgca ttagaggaat acacaactaa taaaagtcaa aaagaaatta
     9781 ctgctttgat gaatcttcaa ccacaaaaag cccaattatt aaaagaaaat ggacaaatgc
     9841 aagaagtaga tgtttctcaa ctaaaggtgg ataacttggt atttgtcgct aaaggagcag
     9901 ctgttccgat agatggcttt ttagaaagca cacaggcaac gatcgatgag tctgcattaa
     9961 gcggtgaatc tgtgcctgta gaaaaatatt taggcgatga gatgtatgca ggaacgctga
    10021 atcaaggaaa tcccatcacg attcgagtaa caaaaacgag ttccgaaact gtctttgcta
    10081 agattatcca attagtagaa gaagcgcaga atacgccaac tcaaacagct tcatttatcg
    10141 aacgaatcga aaataattat gtaaaattga ttttgcttgc tgttcctcta atgatccttc
    10201 tcccccactt tttcctaggt tggagttggg atgaaagctt ttatcgagga atggtattat
    10261 tagttgtggc ttctccttgt gcgcttgtcg catctgctac accagcttct ctagctgctc
    10321 tttcaaattc tgcaaaaaat gggattttaa tcaaaggcgg tatccattta gaaaagcttt
    10381 ctgaattaaa agcgattgcc tttgataaaa caggaacgct cactaaagga aaaccagttg
    10441 taactgacag ctttttcttt gatgaaaagg atttggcaca acaacttctt gttgctatgg
    10501 aacaaaaaac gacgcatcca cttgctcatg cgattttgca atatttcgat tgcacaatac
    10561 ctgaagaaat ccaatactta ccaatagaag aaattactgg ttttggatta caaactacct
    10621 atttaggtgc gcaatggaaa gttggcaagc acgcatatga tcctgagacg atgataatca
    10681 gcaaagagat tgcggaaatg atcgaacgtt tggaaaatca aggcaaaacc gtgatttatc
    10741 tttctaaaga tcagcagtta attgctgttt taggtctgct agatattcca aaagcaaata
    10801 cccaacaagt aatttcctac tttaaatccc aaaacatcca tacaagtatg ataaccggcg
    10861 accattctgg cacagcaaag gccattgctg aacaagtagg gattgaacat tactatgcaa
    10921 gctgtactcc ggaagaaaaa acacaactag tcaaaaaaga gaatgaactt taccaagtaa
    10981 atgcgatggt tggtgatgga gtcaatgatg cgcctgcttt agcagccgct tctttaggtg
    11041 tcgctatggg gcaagggaca gatgccgcta tggatatcgc agacatcgtc ttaatgaaaa
    11101 gcgacttaaa taaatttgtc tacagtcatc ggctatcttt aaaaatgcgg cggatcatca
    11161 aacaaaatat tattttttcg attcttgtta ttctcttgtt gattgcttct aacttcctgc
    11221 aatttttaaa tctacctctt ggagttgtag gacacgaagg aagcacaata ttggttattc
    11281 tgaatggctt gcgtttacta agacctttac ctgatctttc tgattcttca aaaaaatgta
    11341 agtcttgtcc actatacaaa gcgcggctgt cttctgtcaa ataagcaaag tgttttttta
    11401 tgattttgtt tattttatga aaaaaacagc ttatgaatag gtcttgaagg atgaattcct
    11461 acttttgtaa ctttctaaaa acatgttatg attgtttcga agaaagtgag gaatatattt
    11521 catggaaagt tggctttttt taggaattat tttacttgta gcaattttag ctaaaaatca
    11581 aagtctgatg atagcggcag cttttgtttt gattatgaag ctcataccag cctcccgttc
    11641 ctttttccct tggcttcaag gcaaaggaat caatattggg gtgacgatca tcacagcggc
    11701 tattctaatc cctatcgcaa caggagaaat cggtctacgt gatctattag aagcctttaa
    11761 atcccctatt ggctgggtag ctgttttttg cggtgggcta gtggctgtct tatcttccaa
    11821 gggtgtagga ttgattgctt ctgatccaca aatcactgtt gcacttgttt tcggcacgat
    11881 tttaggtgtt gtcttcttaa gaggaatcgc cgccggaccg gtcattgctt ctggtatcac
    11941 ttactgtatc ttacaagtat ttgctttagg aaaatagaac aaattttgtc tattttagga
    12001 gattcttaac acccccaatt tactgatccg tgatatactg acaacgaggt gatacaatgt
    12061 tcgaaaaatt aaagtatttc ataggaacaa tcggctggtt tcttctagcg gtacttttga
    12121 ttctgggctt agcttatcta ttatttcctg atttgataca aaatgtgttt gatactgctt
    12181 tttgattgac ctattaaaac gatatagggg atgctcctgc gatgcagggg ctttttttaa
    12241 tcaatgtttt gtaataattt aggccgtgcc aatgagactt cctatagaat tcgatgctct
    12301 tttttctttt tggctcttct gctctttttt gttatactag attacagtgg acaaaagaaa
    12361 gaatgatcgc atccacttca acgaatatca aaatggaaga attagtgcct gttttcaggt
    12421 tactttgaaa agaaaggaag acgcttgtgg aaacttttga aggtctttta attgatacgt
    12481 acgttttaca agaacagcca atgatgctga ctgggatcaa cttgcagctt gaggaccgtg
    12541 tgatcaatgg cctgcttaaa gatcgctatt tggcaaaata tatcttacgt ttgcccctaa
    12601 ataaatatgt gctggaagta agtggcaaat ggaaccgtcg gaaccagttg gtcataaaaa
    12661 aaatgttgat aaaaaatatc gatgaataca ttaaaataat cggtacacca gaatagcctt
    12721 tactgatcaa aggatactgg ttataaaata actgcagttt cttaatagaa aaacaaagaa
    12781 caacagggaa tcgtatccct tttcaaaaaa aactttgcaa acggttctct ttgttatata
    12841 ataacttagt accaaacatt cccattcaaa ctttgtttaa atagataaat aaaaatctag
    12901 tttggtttga cgctattgcc tcccacaata gcgtcttttt gatttttttc agcttgtact
    12961 atccgttttt actgaaaaaa aatcctaata aaagactgtt aaggaaaaaa acttgtcatg
    13021 ttcatattgc aaagcacgct gcctttaggt ataataatga atgttgaatt atgcggtaac
    13081 acgcgtaaga acttaagtta tcggaggtga aactaatgcc aaacattgaa tctgcaatca
    13141 aacgtgttcg tacaagcgaa aacgctaatg tgaaaaattc atctcaaaca agcgctatgc
    13201 gtactgcaat caaaaaattt gaagatgctg tagcttcagg tgctgacaac gtagatgcgt
    13261 tatataaaga agctgttaaa gctattgata tggctgaatc aaaaggtcta atccacaaaa
    13321 acaaagctaa ccgcgacaaa tctcgtttaa gcaaaaaaat cgctaaataa aagaatcggc
    13381 ttcggccgat ttttttattt gtcaaaaaaa ggacaaaaac aaacgacctt cccgcatgct
    13441 ttgccctcgt ctttcttctt atcgatttct taacaactgc cctgtgcgca aaacgaatag
    13501 ttgaaaactt aattcttttt cgatttgtcc cgttttgatt tgataatcca tctcaactaa
    13561 ttgatcaaac aactgtacca gcaaatgttc atcgaatttt tttacttcct gcatggcaag
    13621 ttttacacga tatggatgga ttttcaatgt ttcagcaata tttgcctgct gataaccaat
    13681 ctttacaaga aattttgtct gtaaaaataa acgtaattga gaaagcaaaa tcgcattaat
    13741 tttgattgtt tcttcccctt gcataactaa atcttcgtat aaacgcaaag cttgttccgt
    13801 cttccctttt aaaatatatt gggtcatgtc aaaaatatta tgttctaacg ttttaggaac
    13861 taattcttct acttctctta ccgtgatttg ctgttgattt tgtccataaa ggaccaattt
    13921 ctgtaactct ctcatcattt tggataaatc taagtcggtc aacctcaaga ataaatcaat
    13981 tgcacttcgt tccattttga ttgaggaatt ctctaaggta ttcatcagat attgacgtac
    14041 ttctttttca ttcaactgtt ggacattgat gataattgct gtttttttca attgtttcgt
    14101 tacttttttc cgttcatcca acttttcata tggcgcaaag aatactaata cagtcgattc
    14161 taatggttct ttcaaataag ccgtcaataa atcagtattt tgttcgattc cattgtttac
    14221 tttttcacct gttaaaaaat aaggattctc tacgaatact aaccgttgat ctccgaaaaa
    14281 cggcaacgtc tctgcttcag ctactacctc atctaaactt gcattttcca tgtcaaaact
    14341 taaaaaattt aagtcatctt cgccctctaa ttggattttt ttgacaattt ctgtccgaac
    14401 ttgatcttgg agaaactttt ctgttcctaa aatcaagtaa caagatgcaa gtttttcttt
    14461 acgtattttt tgtaactctg cttgtatact caaattactc accactttca aaaattatcc
    14521 taccatgagc agatgagaat tactagtcta tcattgtttc cactagccca tgaggatgaa
    14581 aaactggatg ccagcgatag gtgatcattc cttgttgatc cgttcgccat gtttttatct
    14641 gattttcttc tagtgtctcc aatacttcgc tgtgcgggtg accataacga ttatttacgc
    14701 cgcaggatat aatcccatgt tttgcttcaa tatgggaaag aaaatctgtg ttacttgacg
    14761 tacggctacc gtgatgacct aatttgacta catcggcttt cagattagga taaatcaaaa
    14821 gcaattgttt ttccattgct tgattcaaat ctcctaaaaa taaaaagcgc ctattgttat
    14881 attccatcca tagaccaatc gaatcttcat ttcttccctc tcccttttca aaaggagtca
    14941 atacataaag atcataataa ccgctgatcc tgtccccatg tttgatttca atgatctcag
    15001 taccattttt ttgagcttca gataaatgcc tttgtaatgg ctcatttcgt ccagcgcccc
    15061 aaccgatata aatttttttg atagtaaaat gctgagataa cgtgggtaat tctcccacat
    15121 gatccgtatc gtcgtgtgtc aagatgagtt tatcgattac acttatcccc tgacctttta
    15181 gatatggaac gatatttctt tcagcaggag gacgtatcat accttgcgcc cacttttctc
    15241 tttcaaagtg taactgacct ccagtatcga tcaaaatcgt ttcttttcga aaaggacttt
    15301 gcaaaaagat actgtctcct tgaccgacat cgataaaagc gatcgttgaa gaaaagcgta
    15361 aaaatggcaa agtcaaaaaa ataaaagaaa aaagaccaac ataaaacaag tgtttcacag
    15421 gttgttcttt caacctatcc atacaaatca gtaatccgaa aatatacatc ccagatagca
    15481 caaggggcaa acgtcctata atgagagacg accctgaaga aaaatcgatt attcgctcaa
    15541 ataagattaa tccctcttct atcagcaaaa gtaaagtttc cggcagccag cgattgaaga
    15601 gtgtgagaaa taacacacca ggaagaaaaa gaaacttgaa taccggtgca atcagtaatg
    15661 taaaaagact acctaaaata ggccactcat aaaaatgcca tacaatcaac ggcatcgtga
    15721 tcatagtaaa caggacgtga gaggccgttt ttttcaacca atctccatca aaagaaatca
    15781 ggataaacaa aaaactcatg aaaaaactaa gctgtccacc cgcatgaaaa agaaatcgag
    15841 gatcaaatag taaaagaagc caaaagacaa ctgcaaataa gtccatggtg gaataatgct
    15901 tattcagcaa tttgactagc aatcgcaata aaaacagcaa actagcacgc aaaacagaaa
    15961 tagaacttcc tgcaatagaa acataacaga tagttagtag actcaacgga ataatactga
    16021 cgtgtagtgg ccatccgata cgtcgaaata aataatacag ccaccctaaa taaaattgga
    16081 tgtgtagacc cgatagactg aacagatgca gcaaaccact ctccctaaaa atttcttctg
    16141 gttctctgaa tcctgcatct ttatagcccc ataataaaga attaatatat acacttgttt
    16201 tttgcggaaa ttcagattgg acaaaggaga taaaagatcc tctttttctc tgaagccagt
    16261 ttcgccagtg attttgcatg gtgatctgtt caatcttttg aatttggaac cgtccagaaa
    16321 ttctatggtt cctgaagtaa gcttcttggt caaaattata aagattccgc ttttttgctg
    16381 gagagatgaa ctcgccttca gcagtcaatt ctattccctt tcctcggaag ttaagccatg
    16441 ttttcaattc tgcttctgtg tttacttgat aagaaagctg gagcttttgt ttattctctg
    16501 ataaccttcc ttccattgtc aaaaaattac catttgcacg aatcgtatct gtaaatacag
    16561 taatttgcgc agatgttgtt ttttcctcta aaaatgaata ctcttgtagc ctataagaaa
    16621 tggataccgt tatgctacac aaaatacaca agtacgcgat aaaacgtcct tcttttagcg
    16681 aaaaccataa aaaaattccg gcaagaagca aacgataacc ccaattgtca gtgtaataca
    16741 acaaacagat aatcatcgac gtaattgccg gaaaaatcaa ccgatttcga acatgccttt
    16801 ctaaaacgct agacatgttt tcctgttaat tcattttgaa gttttgaaaa atgctgtgag
    16861 tctaaagcaa cttggtgtac agatacacct aattgttcga tcaacgcttg ggcataagga
    16921 tcatttcgat agtcatggag ataattgatc cctttcacac cagcttgcaa caaagccttt
    16981 gtacaggcca aacatggaaa atgtgtgaca tagatttctg aaccttccgt cgggatacca
    17041 agttttgcac actgtaggag tgcattcatc tctgcatgga tcgttcgcaa gcagtgtcca
    17101 tccacgacgt aacacccttc atctatgcag tggacatctc cactgactgc tccattatag
    17161 ccgccagcaa tgatcctttt ttctcgaacg agtgtcgctc ctacttctaa acgtgtacac
    17221 gtactacgta aagataacag tactgcctga gccataaagt actggtccca aggaatgcgt
    17281 tcattatgtg acttatcagt aactttttct ttattcgtat cgcatgcttt tgaagatttt
    17341 tctaacatgt tttatattcc tccgtttttt caagttgatt aaaaagtact cattgcttaa
    17401 acaaaatatt ctttaaatat aacgaatcat cctgtctgac aaaagatcct acccttcact
    17461 gccgaaatga agtccgtcat ccattagccc attataaaaa ttcttcgaat ccatttgttc
    17521 aagaaattcc gtataaaaat cgatacttca caatcatggc gttttgctac ttctgtgaga
    17581 acagagatat attctttgat caacttgtta ttccgatatt tttgttttgt ctcatcgact
    17641 gctggtggcg tgataaagaa agcatgatca gaactatagt cttttttcag ctgaactatc
    17701 atccactgca gattttttgg tacgtttctt tagaaagttg tttatgctct gctagatcat
    17761 tcgtcccaat gagaataaat actttatctg ctgtatagct aagtacatct ttggcaaagc
    17821 gttctcgtag agcttgactg ttattgccgc tgacagccgt attcataata tgaatcccag
    17881 atattttatt ttggagatag acattcagca ttggtttttt taatgtttct ttgcgaacaa
    17941 tcaagctatt tcctatccaa aaatactacc tcctcgtcct gccaagctct tagaattgga
    18001 ttattcttag tatccattag cgtccattta ttgctcgtgc cagtcgattt tgaatcattc
    18061 tatttaattg taacgaagtt ttttagtttt tcaactgtct tttcaccgat accagaaatc
    18121 tcctgcaggt cttccacttt ctggaaggat ccgttttctt ctctaaatcg aatgatttct
    18181 tgcgctttga ctgatccgat cccaggaatc tgctgaagtt ctgatggagt ggctgtattg
    18241 atatttattt tgggaggctc ggaatctgct gtaggctgtt ttccttccga ggatgccaac
    18301 tgatcaagat gttctggcag ctcttcacct acagcaggga tatataggac ttgctgatct
    18361 tctatcttcg cagaaaagtt gattcgatcg ctatccgctt cttctaataa tccacctgca
    18421 cgctttagta catcatagac ccgttcttct gaagaaaagg aatagatacc aggctccttc
    18481 acacttcctt tgatatcggt gtacatgacc tttggacgag catcctcttc tacatcgttt
    18541 ccttcagctg atggatcttc tccactggaa ctaaacgaag aaagtatttc ttttgcagca
    18601 gtctcttctg tttctctata aaatagcaaa tttgataata aaaaaccact tgcgatacaa
    18661 aagataagaa ctatcataga catccaaatg atcaatttgg gtgaagctag tattttcttg
    18721 ctgatttttt ctatcattgt tcttttttca aagaatgacc agtaaaaatc attcattact
    18781 cctttcattt aaaattgaag aaacagtgag ctctggcaaa atcgtccctt caacatctaa
    18841 ttacgtcaat tttttctttt gtttttattt ttatcgtgaa
//
LOCUS       DACDAF010000053        18418 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.053, whole genome shotgun sequence.
ACCESSION   DACDAF010000053 DACDAF010000000
VERSION     DACDAF010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18418
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.053"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(48..260)
                     /locus_tag="IVZ69_001748"
     CDS             complement(48..260)
                     /locus_tag="IVZ69_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183829.1"
                     /translation="MYADKKKIEWLLFDSGKSVRSISIESGVPLTTVSDLANKRSSID
                     NMRFINAMKLNKLAEEIVDINTSTNK"
     gene            447..914
                     /locus_tag="IVZ69_001749"
     CDS             447..914
                     /locus_tag="IVZ69_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183830.1"
                     /translation="MKKKQLWFVSMFAIFFIILSGCSSNKKSEAKEDNSLLQPGTVWK
                     EEVGGLIHNLKIIDDTTWEYSESVWHPDPVQITVKRQKDYEGLERYKIVDSAGIREFI
                     NKPDSLFIVVPYEKDGVKKIIFLGSSKDEKRTKEKLIHDGSELNKYKLQKTSE"
     gene            911..1153
                     /locus_tag="IVZ69_001750"
     CDS             911..1153
                     /locus_tag="IVZ69_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183831.1"
                     /translation="MIASLFIYPEGGITVAKVKTPFEKAASKILERRGVSEIQWKKEV
                     LEKAQFDLLRGKDKDLEEYIYQREREKLVFDEIIKH"
     gene            1171..1473
                     /locus_tag="IVZ69_001751"
     CDS             1171..1473
                     /locus_tag="IVZ69_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183832.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAVAA
                     VASIALGGIFFFFGRRGAENGKTHVGYVLLGVGVILAAASIVVSMFSMFGQTPQGL"
     gene            1545..3599
                     /locus_tag="IVZ69_001752"
     CDS             1545..3599
                     /locus_tag="IVZ69_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183833.1"
                     /translation="MFFTISGNAKLDKELIRKATKKVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLIDLIR
                     LDVFKDTDETMSVEESYRNEKLLQVLEEELESDQRKVNQVSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETDEVEVDPVEA
                     NEESTWTEGDFQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKVKEELNKEEQRVIEEEVQKVKERYEKKRDNAYSLCVE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKHEQIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLEIRKREQD
                     LAEQKMAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSESNE
                     VK"
     gene            3599..6211
                     /locus_tag="IVZ69_001753"
     CDS             3599..6211
                     /locus_tag="IVZ69_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HAP8183834.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            6208..8586
                     /locus_tag="IVZ69_001754"
     CDS             6208..8586
                     /locus_tag="IVZ69_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183835.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            8647..9189
                     /locus_tag="IVZ69_001755"
     CDS             8647..9189
                     /locus_tag="IVZ69_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183836.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            9267..9599
                     /locus_tag="IVZ69_001756"
     CDS             9267..9599
                     /locus_tag="IVZ69_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183837.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            9600..10193
                     /locus_tag="IVZ69_001757"
     CDS             9600..10193
                     /locus_tag="IVZ69_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183838.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            10215..11909
                     /locus_tag="IVZ69_001758"
     CDS             10215..11909
                     /locus_tag="IVZ69_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HAP8183839.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNGATCSAVKSCGLQVV"
     gene            12597..14474
                     /gene="ltrA"
                     /locus_tag="IVZ69_001759"
     CDS             12597..14474
                     /gene="ltrA"
                     /locus_tag="IVZ69_001759"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HAP8183840.1"
                     /translation="MTKETSPKDRKLRHAEYYGMTEIFDKIYSKSLKGDNFKNLMQII
                     ISDNNIVLAYRNIKRNHGSVTRGEDGVTIKDIENLNRNEFVEIVRKRFAHYNPRKVRR
                     VEIPKYNGKLRPLGIPSIWDRIAQQCILQVLEPICEAKFNNHSYGFRPNRSAEHAIAD
                     CMARMNQSHMEYVVDVDIKGFFDEVNHTKLMRQIWSMGIRDKQLLLIIRKMLRAPVVL
                     PNGKLIYPTKGTPQGGILSPLLANINLNEFDWWIANQWEEKDAKELKHHFRKNGAWDK
                     GNIYHKLRKSTTLKEIYLVRYADDFKIFCRNYNEAKKVFYATKMWLQERLKLPISEEK
                     SKITNLSKEESEFLGFTMKLVTKGNKKVVNTHIGTKAQSMIKVKLKKQIKRIQKSPNS
                     KDTFIYIGVYNSMVIGIHNYFKIATHCSVAMRKIARELRPSFEIRLREQGISKEGQYG
                     KYEGYKPYLRSGQIRYIRGFPILPVGYIQHRHPMCKKRNINKYTEEGREAIHKKQQTV
                     EEWKISWLCSNPVLSKRATIEFADNRISKFIAQKGRCAVTGEELILSEMHCHHIIPYH
                     ESKSDSYENLVIVTEEVHRVIHATQSETIEELLKYLKLNPKQKEKLNELRLKVGNEEI
                     S"
     gene            14605..14982
                     /locus_tag="IVZ69_001760"
                     /pseudo
     CDS             14605..14982
                     /locus_tag="IVZ69_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
     gene            14982..16187
                     /locus_tag="IVZ69_001761"
     CDS             14982..16187
                     /locus_tag="IVZ69_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HAP8183841.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWLFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYK
                     LLPSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKF
                     PNSKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSPYYTGCMS
                     IITSNKLTEYDEFAIKHWGEGGNNNGTITGEWTNPFPGSSLDKSSFSGGQLFGTNPGG
                     EFRPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVY
                     QEFANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDP
                     LPFLNSSKK"
     gene            16203..16847
                     /locus_tag="IVZ69_001762"
     CDS             16203..16847
                     /locus_tag="IVZ69_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183842.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQAANTYKIEEVAK
                     NASEKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPTDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVIDFSYFTR"
     gene            16858..17664
                     /locus_tag="IVZ69_001763"
     CDS             16858..17664
                     /locus_tag="IVZ69_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183843.1"
                     /translation="MSKKKGERQRFKKRKSYLRWLGIFMILGFLILASPIYTNQKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIRAKVIKVSDDYFAVKLTHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQLKDQEEIIQKLQEKIDRMTKEKI"
     gene            17686..17916
                     /locus_tag="IVZ69_001764"
     CDS             17686..17916
                     /locus_tag="IVZ69_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183844.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
BASE COUNT         6791 a         2852 c         3802 g         4973 t
ORIGIN      
        1 tcaataaaaa ataagaaaag ccttatataa ttttggcttt tcttatttta tttgttagtt
       61 gaagtattaa tatcaacgat ttcttcagcc aatttattta atttcatagc atttatgaat
      121 ctcatgttgt ctatactaga gcgtttgttg gcaaggtcac ttactgtagt taagggtacg
      181 ccagattcta tggatataga acgaactgat ttaccactat caaacagcaa ccattcgatt
      241 ttctttttat cagcgtacat ttcaatgctc cttcttgttt tttctttatt atagctcttt
      301 tttgtaatga atcacaatat caagagaaaa attttctata gaaaggtgga tttttatgag
      361 tattcgttct ccgtgtatcc aaatgaggtt tgttgctact ttcgttattt gatatactaa
      421 aaataaacaa cgaaagaagg aataaaatga agaaaaagca actatggttt gtctctatgt
      481 ttgcaatatt ttttattatt ttaagtggat gttcaagtaa taagaaatcg gaagctaaag
      541 aagataatag tttattgcaa ccaggaactg tttggaaaga agaagtaggt ggtcttattc
      601 ataatttaaa aattatagat gatactacct gggaatattc tgaaagtgta tggcatccag
      661 atcctgtaca aataacagtt aagaggcaaa aagactatga aggtttagaa agatacaaaa
      721 tagtagattc tgcaggcatt agggaattta taaacaaacc tgattcatta tttattgttg
      781 ttccctatga gaaggatggc gtaaaaaaaa taatttttct tggatctagc aaggatgaga
      841 agcgaacgaa agagaaatta attcatgatg gatcagagtt aaataaatac aaattacaaa
      901 agactagtga gtgattgcta gtctttttat ttatcctgaa ggaggaatca cagtggcaaa
      961 agttaaaaca ccattcgaaa aagccgcgtc taaaatctta gaacgccgtg gtgtttctga
     1021 aatacagtgg aaaaaagaag ttcttgaaaa agcacaattt gacctattac gaggaaaaga
     1081 taaggactta gaagaatata tctatcaacg tgaacgtgaa aaacttgtat tcgatgaaat
     1141 tattaaacat taaaaggagc gaataatctt atgtttgaat caattacaat gaatttttta
     1201 actcaaccga aagtagtagc tgcagttgat atttttagag cattacaaac tgccgcaact
     1261 agtttgaaaa ataatctgat gatttttgct gctgttgcgg cagtggcttc cattgctctt
     1321 ggaggtattt tcttcttctt tgggcgaaga ggagctgaaa acgggaagac acacgtaggt
     1381 tatgtattgt tgggggtagg agttatttta gctgccgctt ctattgtagt ttcaatgttc
     1441 tcaatgtttg gacaaacccc acaaggacta taaaaaaaac aagtaggagg agtaaaaagt
     1501 acgtggctac tttttactcc tttttttatg aaaggagaat attcatgttt tttacgattt
     1561 caggaaatgc aaaattggat aaagagttaa taagaaaagc aacgaagaaa gtgggaaagc
     1621 gtacttcctt tttaccgaaa acaattaaat attctgtcat tgaaacggaa gaacagctac
     1681 atgtgttagg acaagtgtta gaacaagaga atcaatcttc tgttaaattg actctcacgt
     1741 tacatgataa agaaggaaaa atagaaaagg ctggcacaga atacgttttt ggcccactgg
     1801 attatcaaat ttcagaaggt ttttatccta cattgataga tttaatccgc cttgatgtgt
     1861 ttaaagatac ggatgaaact atgagtgtgg aagagtctta tcgaaacgaa aaacttttac
     1921 aagttttaga agaagagtta gagagcgacc aaagaaaagt gaatcaagtg agtgaagtcg
     1981 aagtaaatga agaagtacca tgggaacgac caatctttcc aaagaaggag tcaaaagaaa
     2041 aagagacagt ctatgttgac gaacaagctg atattccgac tcagaaatcg atatttgagg
     2101 aagagaacga tgtgatgggt caattggagg tagatccctt tgaagaaaca atggaggatg
     2161 aagagacgga cgaagtagaa gttgatccag ttgaagctaa tgaagagtca acatggactg
     2221 aaggggattt tcaggaatat attgaaccac ttatcagtga agaagtagaa aaaaacgaaa
     2281 cagagataca aaaggcaact gtatttgatt atattttgga tcaatatccg ccagagcatg
     2341 aatggatgaa agaaaaaaac aaattatttt taaatgagct ttattcgaaa tatcaattac
     2401 cccaaaccta tcaagcattt ttagagagta aagaagaatt aatctcacag ggtaaaggca
     2461 cacttttaga acagttagag tctgtccaat caacaaattg gcatgagctt gcacaagaag
     2521 atttattagc cacctttgaa gaacgtcaac aagaaacaga tcaagaaatt aatgagtatg
     2581 cgacggaaca gtcgtctaat tgggagaaag taaaagagga actaaataaa gaagaacagc
     2641 gagtgattga agaagaagta caaaaagtca aagagcggta cgaaaagaaa cgcgacaatg
     2701 cttattcctt gtgtgtagaa aagatcaaca attttactaa gacgaatcaa gaagcgttat
     2761 cgaaagaaaa agaaaacttg ttaaaagaac gtattaaaga acgaaaagaa gagttctacc
     2821 gcggtttacg tacagataag ctaaagatta gcaaagaatt aaatgaacaa ctgaataagc
     2881 tatatcaaac aacgactgaa gttcttatgg aaaaacacga acagatccag caagaattac
     2941 aagtacaaat tccaaaatgg aaaaaagagt atgaaattca acaacaagaa ttgaaagaac
     3001 aagaagaaaa acaacggcaa aaagaaaaag agcgtgaaca attagaaata agaaaacggg
     3061 aacaggatct tgcggaacaa aaaatggcga tagaaaaaca acggttagag caagaaaagg
     3121 aaaaagaagc agctgctcgt aaggaacgtc aagaacaaat ggatacattg cgtcaagcac
     3181 agttgaatta tctagcacaa cctcaaccag tagctgctgt tcaaacgcca gtgaacaacc
     3241 aagcaaattt aactccttca ccccagcgtt cctttaacgg atggatggtg ggatgtattg
     3301 caagtttaag cttgcttcta ggtggaggaa cagtatttgc ttttaatcat atcaatcaat
     3361 cttcacaggc tgattctgta gccacaacgg cgtcaatcaa ggaagaagcc caggaacaag
     3421 caagaaaaga gtatgaacaa caattagaag aattattgaa tcgtaccaat cagtcaacaa
     3481 cagagtcaag catggaaaat agcaaagaga gtgattctag taaggctaaa gaaggatcaa
     3541 gcgattcaac tgtacaatca aacacttccg aaagttcaga atcaaatgag gtgaaataat
     3601 gcgtgttaga gaaacaacga agcgaaaaga caaacgattc aatttagaaa agaataggta
     3661 tctttctcat ttctatcgct atactccctc aggagaagag ctaccagaaa aacatgacaa
     3721 acgcatttcg aaaaagattt tttatagtgg acttgtatac ctccctttag agtatttagt
     3781 aacaagagta ccagaagttt tcaaccgatt ggaaattgtt aagggaagct tacaaggaat
     3841 aaatctgttt caattacagg aaatgccaca ggtctttcat tttgattcag ctggtttttg
     3901 gaatccattt actcctacaa ctagtttggg tacacgttta gcaatttcga cagtttgtgt
     3961 ggttccagct gtacttatgg gattgaaaat ggacatgtgg tttcgtcctc tagcagatgg
     4021 acaaaaaggg gataatcgat taatgacctt aaaagaaatc caacagattt atccgcaaat
     4081 acctgaaaca aaaactactt ttccaggtta tggaggtatt ccaatcacac attacaaaaa
     4141 atattggtac attcaaacag atactgttaa tacgtgtatt gttggtacct ctcgatcagg
     4201 gaaaggtcag attgaagtgt tagccaccat tgacaattta tctcgtgcag aaaaacaaag
     4261 ttcaatggtc gttaatgatc caaaaacaga attatatgtt ggtagtaaag atgaactaga
     4321 agctagaggg tatgatgtat atgcctttaa tatcaccgat ccactgcaat caatgagtga
     4381 taatccattg gcactcattg tgaaatactg gaagcgagga gacatagaca ccgcaacaca
     4441 gttaaccaat acttttacga atacgattta ttatgatgca aatgcttcag acaataaata
     4501 ctttaacgaa aatgcgcaga aagctgtcaa tgcgcttatt tttgcgttat tggaacaagc
     4561 ggatcaaaca ggggattact ccaaattaac accaaataat ctcgttgaac tactttcaga
     4621 aattggcggt tttaattatt atccagatcc tgagaatgaa ttcaagcagc tcaatgcctt
     4681 agatgagttc atgaatcagt taccccctgg aaatatagca aaaaaacaat atggggcaac
     4741 aaaaattgga tctgataaag cgaaagggaa tatcttgtct acggcaatta caggattgaa
     4801 tccatttacc ctaacgaaaa ttgcgaagat gacttctcaa tcgaccattg attacaagtc
     4861 cattggtttt ccgaagtatt tggatctcaa attacatgaa agcctattaa atcaacgcat
     4921 tgtcgtggaa ttttatcata agggaaagaa atttcacgag gaacgagtca aagttggcta
     4981 tcgtggtttt tgtgaaatca actttgattg tcatttagag cagggagatc atgtttgctt
     5041 aaaatacaat catcaaggaa aacaatatgt tgcttggtat gagttttctc aaaaagtatt
     5101 gaaagacgaa gagggaaaaa tcgtttatcg aaaaaaacga ggagaaactc atttgccaga
     5161 actagaaaaa gaagccgttc taacattaga tgagaagaaa agtaacctat tagtagagtc
     5221 tattcggatg cactataccg ataaaccaat ggctattttt atgttaacgc ctgattatga
     5281 tccatctaac catatcattg ttagcatctt tcttagtcag ttgtataaag aattatctac
     5341 gcaatgtgtt aagactaaag gagataaatg tcaccgtagg attcatttta ttttagatga
     5401 atttggaaat atgccaccga tggacaacat ggaaggaatc atgacggtta cggcaggtcg
     5461 taatatgtta tgggatctgt ttattcaatc ttatcagcaa ctttatgcga agtatggaga
     5521 acaaaacgca gcgattatca aagaaaattg tcagacacat atttatatta tgtcgacaga
     5581 tgataatacc atcgaagaat tttctaaaaa agtggggaat aagacggttg aacaagagaa
     5641 cagtaccatc aattcattag gtatgaatac tcatatcaat cgcaatgttg attcagatcg
     5701 tatcttaact cctgaaagaa tttctacttt tttagaaggt gaaacgattg tactcgctcc
     5761 tttaaaacga caagatttga aaggtcataa aatacggccg tatcctattt ttaatcatgg
     5821 ggaaacgaat cttccttatg cttatcaata tattgaagat ttcaatccat cgtgggatat
     5881 caatgatata gacatacatt gtacacatgc ggacttggat cttaaggctt tacaaattga
     5941 ttatgattat ttcctaccag atgaatatgc tagaaatctc tatcatggac tgcatgatca
     6001 attagaagaa aaaaacgaag aaaatatgtt ttataaaatc gttcaatctt ttgagaatga
     6061 gacggctaaa aaattgttaa ttcaatttta cgaagaacaa gcaacggatc gtcttcaaga
     6121 atatgttgaa aagttgatca aaaatgaaga aatttctgaa atgattagga aacggctgtt
     6181 attggaagct gaaaaggcgg tgaaagaatg atcattggag gaattttctc tggcatagcc
     6241 gactggtggt caggtttatt cggagaaggg gatgcagatc ccaaaaccgt aacgaaagtc
     6301 ttacaagatt atggtaatta tctgcagtat caagatgtat tcagttggat ttgtaatact
     6361 tttttatggg gattgatcaa agggttatat aatctcaata ctttattaga aaaaacaatt
     6421 tatcaaagct ttgatttaaa agacttattg aacgccgctg gtgttaatga actatttcaa
     6481 agtttgatta gtaaggtatt ggctcttttt tgtgtcgtca cattaattta tttaggcttg
     6541 aaatttttta tgagtaaaca cccaccgaaa gtcaaaaata tcttggttaa tttatttatg
     6601 gccatgatct tgatttttgg tggtagttct ttaatcgatg aagggttaaa tatcagtaaa
     6661 aacttttatg gagacgtcac tgcagcaaat aaagcagata aaacgggttc acctgctttt
     6721 caaattattc aaaataatgt gattgatgtc agtacattac tagcgactga cccgaataaa
     6781 gtagaatcct taccaacaga taaaagaaat gctttaacag cgaaaaattt caaaacagcg
     6841 aatatcaatg ggattattac acctgatcaa gctaagaaaa tgtctgaatc aagtgatatt
     6901 agtacagtac aaaaagatcg gttaaaggca ttacagtatc gactagagtt agacgataat
     6961 gggaaagaaa tccctgttca aattagtgat gaaggtttag caaaatatgt gtatacgtca
     7021 ggctatcgtc gatacattag tagtccaggg attattttgg ctggggaatc ttctttgtcg
     7081 gtagcctatt tatttatttt gtttacaatc gttacttgca ttattgagct agtatttaaa
     7141 aaattctatt tagtaattgc cgcgtcaacg gactttgaga caggacaacg gatgaaaagt
     7201 gcgatagaag atatttctca atccttcttg ttattggcgt ttacgatttt agaattacga
     7261 atctatacat taatgctttc aggtatcggt gatttgcatg cggtaggaaa gatcaatgga
     7321 ttcttgtatg ttgttgcttt aattgtgcta actattgcgc tattcaaagg ctctcaatcg
     7381 gttacgaaga ttttcggtgt tgatacgagt ctgaaaaacg gcagcaattc tcttcttagc
     7441 atgtttgcct taggaaatat tgcgaaaaat gtgggtagcg gagctaaaaa ccttgcaagt
     7501 gctggtaaga gtggtttaag ccatttaaat gatattcgta agaatggatt tggccatcga
     7561 aaagatatta cccatgataa cggggaagaa caatcagacg ataaagctac aactgtacct
     7621 aatagtaaga agacagtttc cgaaatgttc gggaaagcga aaaatggtgt ttctaaagcc
     7681 gcagaaggtc ttggttacgt caatgaacgt gggttaaaag gaacagttga agatcttaca
     7741 gaaaaagcca aagacacctt agaagagaaa ttagacggca cgagagctaa agaatttgct
     7801 gaagctgtga agaatccatc cgaagcacta gaaaaacaaa aagaaaaagc ttcagcagtc
     7861 aaagaaggac taaaagatgc gtatggtgaa ggacaagtca atgcagcagt gaaggcaaat
     7921 acaacaagtg aaaaagaaaa tcaagaaggt gcagcgattc cttcagccaa agatcaccaa
     7981 gatgagttac attctaacga aaattcgatc ggagaaaaag attcagaaga aggacaacat
     8041 ggtcagttac caaaaaccga tccagaacaa tatcgttata aatctaacat taattctgaa
     8101 aacgaaaaac gcatttcaga tttaccaaaa cgaaatcaag aagtacaaac ggatgaggat
     8161 tccatcgatc tgccaaatga taatggcatc gaagttggaa ctgaaaaatc aacgaaaatt
     8221 ggtttgccta agacacaaaa tttaccaatg aaagatagtc gtttgaatca attcaaagag
     8281 aatgatcaaa gctttgttca tcaatcacct gcaggtactg ttcaaatgaa atcaagtcgt
     8341 ttgcctgaaa atggaaatct gacaactgtt tcttacaatt tagctgaaag tggtgaaaca
     8401 gagaatgcgt ccgttcaaaa tattgtgaca aaagaagctg cacctaagcc aatcaataaa
     8461 gttcataatg gatacagacc agcaaacgta gcatttactg caccgacaaa aataaatgtg
     8521 acaagagaaa ctaaaaacag gaacaatgaa ttgaaagaac aactattgaa ggatatcaaa
     8581 ccataaaagg cctatttaag ggcctttttc tttataaaac aagtttaaaa tggaaaggag
     8641 aaaattgtgg aggatatttt aatagctacg tttataactg cactgggagc atttttaacg
     8701 atatttgtgg tgactattaa aggatttaaa gatacggata gtttacaaaa agatcatcag
     8761 tctattttag atggtcaaaa aacacatacc gaaagcatta ttgtacacct ttcagaagga
     8821 ttcacttatt tgaaagatgc tatgcccaca ttcacagtaa aattaacgga aatatttcat
     8881 tctgttgagc aaatatcgtc agaattgaaa gagcaaagac aacaaaaaga tcgtcaactt
     8941 ggctcactta attttaggca agaaacgata caagaatcat tggagaatgt aaatcgatta
     9001 aacgatgaaa tgcaacgagt tcatttggaa aatgaagaat tacgcgcaca aaattatgat
     9061 ttaattcaaa agaaaagaaa tctggaacaa aaaattgttg aattaaaaga agaaaatcgt
     9121 caattgaatt atcaattacg acgaggaaaa aatcgttctc gtgatttagg aaatgaatta
     9181 gagttgtaat atttagaaaa acgctgtgag aaatcacagt gttttttatt tctaaaaata
     9241 caaaatataa ggggtatggt tatattatgg ataaatacat tcatatgaaa aatcctccaa
     9301 gatttagtgg ggaatggaag tttttcgcct ttttcttttt agatctatta acgcttggtg
     9361 gctgcttttt ttgggcgaaa atagtcaata atcttgtcca cttaccactc ttttttgcac
     9421 tcttgaatta tggattatgg cttgcgatag cgttagtgat tgtttggcga ccctataata
     9481 accctggtca acgccaaatt tttgcgatta tcgaatctat tttctttacg gataagaacc
     9541 actatcatgc gttagatcct aaccgaaatt atcatggtac gtataaggag gatgaataaa
     9601 tgcgagtcaa aggacaaaat tcagttgata agaaatccat tttgcagttt ggaaaaccag
     9661 aagagcgctc tatcttggac ttatttccat ataaatcctg tacagaagag ggagtcttaa
     9721 ttactagaga agatcatttt cagcgttatt atcgtgtcgt ttccactgac gtggagggat
     9781 taaatgaaca agagaaacta gaacgaatga atcagttgac caccgtcatg cgtacgtatg
     9841 tgccaacaat taagttagtt agtttgacca cagagacgga tctaacggaa caaatcgtgc
     9901 aaaagcggca gttattagat aaaaatcgta tggaacagtc actaggaaga aatctacagc
     9961 gattaagaaa atatgaaaag aaattagtag aggagatcca ggaattaaaa cgggcagaac
    10021 aagaacgtcc tgacttaagc ttctttttcg ttattgaagg aaagacaatc aaggatttac
    10081 aaactagaaa tcgtcagtta atgcgatcta gtggcatttt agggttaaaa ccactctaca
    10141 aaaaagaatt gattaagatt ctttatcgaa tgaacaacat gaatgacgaa taaaaaagat
    10201 ggaggaaatg attcatgcta gatgtgataa aaacagcttt ttcaacgcaa agtaatcaaa
    10261 aggtgattga tccattaaaa caacttggta atcgtgaaat agagatttta aaatcaaaag
    10321 gttatgattt agatttctta aaacaagtga tgccacaagg tgggttgaat tttgatgaag
    10381 aatatgtgac ctatggaaat ggttattcac gatgtgtgac agtttatcat tacacaaaaa
    10441 atcctactct tttttggttg gccaatctca tgaacaatcc tcatacagtg gccacactag
    10501 atgttagcac agatgaaaag caaaaagtga ttgatcaaat caaccgcgca ttagatgaat
    10561 taaatgatcg atcagataat gaacgaaaag cgactgaccg aaataaaagt gcggaagaat
    10621 acctggaact agcggaatat gcccgaaaat tgacttctaa tggggaaatt tctaaacaag
    10681 tcaaagtgag agtacatgtt tacggaaata cgatccaaga agtggatgaa cgggcgcagg
    10741 aactgatcga aaatctaaaa gggatggatt atcgtgcggt gacttatctg cataaaacca
    10801 aacgagattg gcaatcgatg tttaccatgt tcgatgaaca agctgaatgg tttggaaata
    10861 tcaaagggca atcacttcca tcgttaaaca ttggcggagg attcccgttc caccaccaaa
    10921 cgctaaaaga tccaggaggc acacaatatg gggaaaccat gacaggcggc ccatttgtct
    10981 ggaatgccac gtataaaaat agtgtacgtt tatctaccaa taccttgctt ctaggaatga
    11041 tgggagctgg taaatcgacc gttcttaaaa tgatcgcgga agcccattta gctgcaggag
    11101 actttatttg gggctttgaa aagggaaaag actttattcc tttcttaaag gaatataacg
    11161 gtattatggt gcgtttagac ggatctgacg gaatgatcaa tcctttagag atatttgcca
    11221 cacggacgta tgatgaagca tccagtttat atgacgatgg atcagtcaaa gatttgaaga
    11281 tcaatgaagc agcgtcctat caaacacact tagacaaagt ggtctatcag gtacagttag
    11341 tgagtcctca gctaaaagga acgatgaaag cagaatttaa gacctactta aatcgttttt
    11401 atgaagagta tggaacagta ccacgcggct ttacttcctc aaattcgcgt tcaaatactg
    11461 atacgcaagt cacagggaaa gatccagaag cttatccgac gttcaaagaa tttttagcct
    11521 ttttaggaca actggaacta ccaggggctt cccaagagaa aaagaatcgg aaagaagaaa
    11581 tggagtctat cgtggaatcc ttatgtgaga cttatggcat gatttttgat ggtcatagta
    11641 cgattcgaca ccttgaccaa caacagttgg tcttttttga cattgactct attacaggcc
    11701 tagatcgagg ggtacaacaa tgtcagatgt acatggccat gacgttgatt tggaatcagg
    11761 cattgattca aggacgaaga caacgacgct taattaaaga aaaacaaatg gaagaacaag
    11821 acttcaaacg cttcttggcg atgattgatg agtgccataa tggtgcgacc tgttctgcag
    11881 tgaaaagctg tgggttgcaa gtagtctaaa aactattgta ataactctta taacgagaag
    11941 tcaaatgagt gggtaacgcc acaaagggct tccactgata ctccgacatg caacaagtag
    12001 tttatgcaga ccaacgttgt gtgaagctcg gtgaagtcgg ctgaaggata ccgtaaggta
    12061 aaagaaatag tgaataccac gaaagttctc tagaggtaaa gggtgtatcc gataagtcgg
    12121 gtgtccaaaa aaacttaata tggtgagtat gtacaaacgt actgacgaac tagcgaatgt
    12181 actgtccgaa aggcatagct cctagaaatg ggagagacag tgagcaaaaa atcactcatt
    12241 gtgctaactt gtggttgagt aaaagtcgtt gttatgaaag accatgctgc gttacaggcg
    12301 taggagaagt tagggggcaa aagctagcat ctaagttaag gcatgtggat agatataagg
    12361 gaacagggga agccatcaac atggagagtg catactcgat gaagtggtag taagaaatat
    12421 gtgaatgaca aataacttac tttagtgatg gtgaaagtag agtcacgact gatgaaggtt
    12481 ctgtaatgga actggaggaa caggctcgat tcgtctgtaa aagtcatgaa acccgttcaa
    12541 ccatgggatt ctcgtatgac taaaaaggtc acgagccaat tggagcgtga taaaccatga
    12601 caaaagaaac aagtccaaaa gataggaagt tgcggcatgc agaatattat ggcatgacgg
    12661 aaatcttcga taagatatac tccaaaagtt tgaagggaga taatttcaag aatctaatgc
    12721 agattatcat ttctgataac aacattgtcc tagcatatcg taatatcaag agaaatcacg
    12781 gtagtgtgac aagaggagaa gatggagtaa cgattaaaga tattgaaaat ctcaaccgta
    12841 atgaattcgt agaaattgtt aggaagcgat tcgcacatta taaccctcgg aaagtaaggc
    12901 gtgtagaaat tcctaaatat aatggtaaat taagaccgtt gggtattcca tcaatatggg
    12961 atagaatcgc gcagcaatgc atcttacaag tattagaacc aatatgtgaa gcaaaattca
    13021 ataatcacag ctatggtttc cgcccaaata gatcagcaga acacgcaata gcagattgta
    13081 tggcccgaat gaatcaaagt cacatggaat atgtggtaga tgtagatatc aaaggtttct
    13141 tcgacgaagt caatcatact aaactcatga gacaaatctg gtctatgggt atacgagaca
    13201 aacagcttct cttaatcatt aggaaaatgt taagagcacc cgtagtactt ccaaatggga
    13261 agttgatata cccaacaaaa ggaacaccac aaggcggaat acttagccca ttacttgcga
    13321 acatcaatct caacgaattt gactggtgga tagcaaatca gtgggaggaa aaagatgcca
    13381 aagagctaaa acatcatttt aggaaaaatg gagcttggga taaaggtaat atctatcaca
    13441 agctcagaaa gagtacaact ctaaaagaaa tatacctagt gagatacgca gatgatttta
    13501 aaattttctg tagaaattat aatgaagcga aaaaagtttt ctatgcaact aaaatgtggt
    13561 tacaggagcg tctaaagtta ccaatatctg aagaaaagtc aaaaatcaca aatctttcaa
    13621 aagaagaaag tgaattttta ggctttacga tgaaattagt gaccaaaggt aacaaaaagg
    13681 ttgttaatac gcatataggt acaaaagcac aaagcatgat taaagtgaaa ctaaaaaaac
    13741 aaatcaaacg aattcaaaaa agtcctaata gcaaagatac ctttatctat attggagtct
    13801 ataacagtat ggttattggg attcataatt acttcaaaat tgcgactcat tgtagtgtag
    13861 caatgcgaaa aattgcaaga gaactcagac caagttttga aatacgacta cgagaacaag
    13921 gaatctcaaa agaaggacaa tacggaaagt acgaaggata caagccttac ctacggtcag
    13981 gacaaatacg atatataaga gggtttccaa tattaccagt agggtatatt caacacagac
    14041 atccgatgtg taaaaaaaga aatattaata aatacaccga agaaggtagg gaagccattc
    14101 ataagaagca acaaaccgta gaagaatgga agatatcgtg gttgtgtagc aatccagtgc
    14161 ttagtaagag agcaacgatt gaatttgcgg acaatcgaat ttcaaaattc atcgctcaaa
    14221 agggaagatg tgcagtaaca ggtgaggagc ttatcttatc tgaaatgcat tgtcatcata
    14281 ttatccctta tcatgaaagc aaaagtgata gctatgaaaa cctagtgatt gttactgagg
    14341 aggttcatcg ggtaatacac gctacacaaa gtgaaacgat tgaggaactt ctaaaatatc
    14401 taaaattaaa tccaaaacaa aaagaaaaac tcaatgagtt gagattaaaa gttggtaacg
    14461 aagaaatatc ttaataaata tttgtaggac gggaaaacag aatgtctttt atagacgagg
    14521 gaacgccgta tgcggtgaaa gtcgcacgta cggtgtggac tgggggaaaa gacggagata
    14581 atatcaaact cttacctatc agtatcgatt aatccagatt ttattgaaac ggtaaattat
    14641 gtcacaaact ttcaacgaga aatgcgtaaa gtagaagcaa tgactgtttt agctacacaa
    14701 tccccacaag aaatggtgcc agaaaatatg tcttctgata acttctcgaa actgaagaaa
    14761 gtctttgaat tttcttctac gaagatcttt atgcgtatgg atgaatctat tttacgtcat
    14821 atagaaggat tagtgggtaa atcaatgacg aactcagaat tagaatccat tcctcaacaa
    14881 aatcaaggag acgctgtgat caattttggc tcaaaagaaa ccattcgtgt tcattttagt
    14941 ccgaacaaac gtcaattaaa attgtttgat ggaggaaaat aatggaaaac caaaatgaaa
    15001 gtttaatcaa gcagtatgtt aagcgtcgtg caaagcggcg cttatttttg tggttgtttg
    15061 gtacttctgc aggtttgatt actattttga tcactgtgtt cgtgacccta tttctaatac
    15121 ttgcggcggg ctcgattgat aattcggatt cagattcaag cagtggtggc gaagctttta
    15181 caggagaata ttcggaaggc ttaccgattt ataaagaaat caaaggaaga ggcccttttt
    15241 ctgatgagat tgcgcaatat gccgtaggtg cagcagtgaa atataaatta ttaccaagtg
    15301 tgatcctttc gcaatacggt tacgaatcag cgtttggtac atcggcgtcc gcaagaaatg
    15361 atctcaacta ttttgggatt acttggtttg atggttgtct gtttcctaaa ggaactgcac
    15421 gaggaattgg tggcattgaa ggtggctggt acatgaagtt tcccaactca aaagctgcat
    15481 tttcctatta cggctttatg gtagccacac aatccaattt taatgcttgt gtaggaaata
    15541 aaagccctgg cgcaagctta ttgatcttag gacgaggcgg ttatgccgct gcaggaatta
    15601 cggaagatag tccgtattat acaggttgta tgtcaattat cacttctaat aaattaaccg
    15661 aatatgatga attcgccatc aaacattggg gtgaaggtgg caataacaac ggcacgatta
    15721 ctggtgaatg gacgaatcca ttccctggca gcagtttaga taaaagttcc ttcagcggtg
    15781 gtcaattatt tggaacgaat ccaggcggtg aattccgtcc gaacggcttc catgatggat
    15841 tagattttgg ttcagttgat catccaggaa gtgagattca tgcggttcat ggcggaaaag
    15901 tcgtgtacgt tggcaatcct ggtatttcag gtttgggcgc gtgtgtgatc gtgattaatt
    15961 acgatggctt gaatatggtg tatcaagaat ttgcaaatag tacaggaaat tctcgagtga
    16021 aagtaggcga tcaagtgaaa gttggtcaag taattgggat acgagataca gcacacttgc
    16081 atttaggatt tactcgaatg gattggcgtc aagcacaagg acatgcattc attgatgatg
    16141 gtacatggat cgatccgtta ccatttttga atagcagtaa aaaatagatc aggagaaaaa
    16201 atatggaaaa taaaacgtta aaaatcgtct taacagctgc aattagcgtt agtttaatcg
    16261 gcaatattgc gttgttttgg cagctgaaag aggaacaagc agcaaatacc tataaaattg
    16321 aagaagtggc taaaaacgcg tctgagaagc tcaaaaaaaa ttcctctgag gcacaggcga
    16381 agatcgacaa gttaaatcaa accatcaatg agaaaaacca agaaatcgat cagctgaagc
    16441 aacaagatgg cacaaaagca aaagaggaag taactgaagc acaaagaaag acggcagaag
    16501 agttcggtca attggccatt gataaatcat taagcagaaa tgaattaacg gaaaaactaa
    16561 aagatgtcgc aacccaagaa gtgatcgaca aattaagtcc tacagacgat gatcaccaac
    16621 atgatgatta cggaagttac tcctttacat taggtgacgt gcaaacttac gctcaaacaa
    16681 gcagtgtaaa agaggaacaa aattttgtcg tatttgttga ttatacaatc ggcaatccgc
    16741 aattcaaaga tgtcaaacca caaaaaataa aaggtggatt aactgtcact gaaaaacaag
    16801 tagatggtca atggaaagtc atagacttta gttatttcac tcgttaggag gaagaaaatg
    16861 agtaagaaaa aaggagaaag acaacgtttc aaaaaacgaa aaagttatct tagatggctg
    16921 ggaatcttta tgattctcgg ctttttgatt cttgctagtc cgatttatac gaatcagaag
    16981 gtagatatac cagatgaggt aagcacgaac gcctttttaa acacgaaaga gctgacaatg
    17041 gtttcaaaag aaaaaggagc gaaccagcaa ttagtttttg aatttgcgat cgatgatgaa
    17101 gatcaaagct tgttaaaaga actggctaat cttaattatc gcgtagaagt aaagacagct
    17161 aaaggggatt atcaagcaat acgagccaaa gtgattaagg tgtctgatga ttattttgca
    17221 gtgaagctaa cgcatgtacc agaagaatat atcgccatgc gtttaaccat tattcctgaa
    17281 aaaattgatc caaaagtgga tatgcaagaa ccacaagatc tgatttatta cgtgcacgaa
    17341 gataaggtta aagatcaagt gaaagatgaa gattatgaac aacacgcgat caattacaaa
    17401 gtgaaaggat acaagaaaga acaaaaagca gctcaaaaac aaatggaatc tttccaagca
    17461 accattgatt tgaatgaaga attagtgaag aagctaaaag atcaattgcc ttatcaagtc
    17521 gcagatgatc aggaaaatac tgaaaacaag attaatagct accagcaaga aattgaaaca
    17581 tcgaaaacgc aactgaaaga tcaagaagag atcattcaaa aacttcaaga aaaaattgat
    17641 cgtatgacaa aagaaaagat ttagaaggac aggtggagtg aaaaaatgaa gcgaacaaac
    17701 ttggctgaca aagatacttt cgctgagcag aaagtattga ttaaagccta tctcaaagtt
    17761 gtaaaagcta aagaaatatg tcgagaagtg aatttatcta acacaacaat atctgagttg
    17821 aagaatggtc gaaagaattt agatacttta aaattcagat catttgaagc tctatatgta
    17881 gctgctaaaa aatattttac agctgataac aaataaaaaa caggagtatt ttatgtgaaa
    17941 aaagtatata aaaaatgctt atgaatcagc tatatcacct taaccatttg ttaatgagat
    18001 gggagaaaac attaaccacg attctaacgc aaacatcaag cacataaaac atttaacact
    18061 cctcctttct ggctgaagat ttcaaccaaa caggaagaca gcgtatcaat tatagcatac
    18121 actttttctt aaattcattt ttcatatgac aaaatatttc cttctaatcg acaaagttag
    18181 aaggattttt tattgtctaa atacacaaat aaccttaatt tttaaagagc ataaggaaac
    18241 gtgatatcac tttctcacga aaggtgttag gtaggctgtg cctaccacgt ttctaagaaa
    18301 gataaatgat atcaaaattt tggatttgtg tgtagatttg tgggtaggat gaaagcgaat
    18361 gtgggcagta aaataagcgt ttgtgtgtag caaaatcaaa aaatgtgtag ggatatgt
//
LOCUS       DACDAF010000054        18108 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.054, whole genome shotgun sequence.
ACCESSION   DACDAF010000054 DACDAF010000000
VERSION     DACDAF010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18108)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18108)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18108
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.054"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(12..695)
                     /locus_tag="IVZ69_001765"
     CDS             complement(12..695)
                     /locus_tag="IVZ69_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP8183845.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            complement(713..1330)
                     /locus_tag="IVZ69_001766"
     CDS             complement(713..1330)
                     /locus_tag="IVZ69_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HAP8183846.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            complement(1340..2164)
                     /locus_tag="IVZ69_001767"
     CDS             complement(1340..2164)
                     /locus_tag="IVZ69_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HAP8183847.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            complement(2157..2717)
                     /locus_tag="IVZ69_001768"
     CDS             complement(2157..2717)
                     /locus_tag="IVZ69_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183848.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            2891..3847
                     /locus_tag="IVZ69_001769"
     CDS             2891..3847
                     /locus_tag="IVZ69_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP8183849.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            complement(4152..5108)
                     /locus_tag="IVZ69_001770"
     CDS             complement(4152..5108)
                     /locus_tag="IVZ69_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HAP8183850.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            5212..5814
                     /locus_tag="IVZ69_001771"
     CDS             5212..5814
                     /locus_tag="IVZ69_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HAP8183851.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            complement(5902..7401)
                     /locus_tag="IVZ69_001772"
     CDS             complement(5902..7401)
                     /locus_tag="IVZ69_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HAP8183852.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(7417..7941)
                     /locus_tag="IVZ69_001773"
     CDS             complement(7417..7941)
                     /locus_tag="IVZ69_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183853.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            8239..8988
                     /locus_tag="IVZ69_001774"
     CDS             8239..8988
                     /locus_tag="IVZ69_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HAP8183854.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            8979..9764
                     /locus_tag="IVZ69_001775"
     CDS             8979..9764
                     /locus_tag="IVZ69_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HAP8183855.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            9733..10449
                     /locus_tag="IVZ69_001776"
     CDS             9733..10449
                     /locus_tag="IVZ69_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HAP8183856.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(10551..11570)
                     /locus_tag="IVZ69_001777"
     CDS             complement(10551..11570)
                     /locus_tag="IVZ69_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HAP8183857.1"
                     /translation="MRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIVSAKDH
                     DAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVPSYSPN
                     AIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRIGLTEA
                     VLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQMINEG
                     FLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSFKPWET
                     IPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNEVSLPK
                     ARQLR"
     gene            complement(11589..12647)
                     /locus_tag="IVZ69_001778"
     CDS             complement(11589..12647)
                     /locus_tag="IVZ69_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014372913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HAP8183858.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            complement(12868..14016)
                     /gene="nagA"
                     /locus_tag="IVZ69_001779"
     CDS             complement(12868..14016)
                     /gene="nagA"
                     /locus_tag="IVZ69_001779"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HAP8183859.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(14092..14928)
                     /locus_tag="IVZ69_001780"
     CDS             complement(14092..14928)
                     /locus_tag="IVZ69_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8183860.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(15112..16329)
                     /locus_tag="IVZ69_001781"
     CDS             complement(15112..16329)
                     /locus_tag="IVZ69_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP8183861.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            16712..16795
                     /locus_tag="IVZ69_001782"
     tRNA            16712..16795
                     /locus_tag="IVZ69_001782"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16746..16748,aa:Leu,seq:gag)
     gene            complement(17035..18033)
                     /locus_tag="IVZ69_001783"
     CDS             complement(17035..18033)
                     /locus_tag="IVZ69_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183862.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFFLDMNILFLLLFFLIFLLTYRKC
                     QNYYVRILTALPFFLNLIIYFGNTMGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLS
                     LFYPGTWIATLVVLALLLCLIVGIYLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVW
                     ASGMRTYYILYVVIAILVLMAVKELMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT         5387 a         3731 c         3145 g         5845 t
ORIGIN      
        1 attctcacct gttattcatg attctttttc tcagtttccc gatatttttc cattttacga
       61 ctaaaaagct ctccgctact tggtggcgta tatgtgatgg catttgctcc tgcttgaatg
      121 gtctcagcaa tactttcttc cgttggacca cctgtcgcaa tgataggaag ttcaggatat
      181 tttttacgaa aatggcgtac tgcttctgca gtttctttac ctgcactgat attgataatc
      241 gaaataccag ctgctaactt ttcatctatt tctgtatatt tcgacgttac cgtactgata
      301 actggaatat caactactcg acaaacttct tttactgtct ctaaaggcgt aggaccgttc
      361 aaaacgaccc ctaacgaacc ttgcgcttct gcgaacatgc tcatgtagga agaacgagca
      421 ccttgtgtca aaccaccacc tacaccggag aaaactggaa tgtcagctgc ctcaataatg
      481 cttttagtaa tcgctggatg aggtgtaaaa ggatacacag caattactgc attcgcattt
      541 gtattacgta tgatcgcaat atccgtagta aagatgatcg aacggatcaa ttttccaaat
      601 atcttgatcc cgcttgcttc taaaatgatt tccggtactc ttacgatatc ttttctcaat
      661 tccgtcatga tttctggcgt aaattgttct gccatcagcc acttctcctt tgctatctcc
      721 ggtcatactg attcaattga tacgtctcga tgacctggat gattttttgc gcataaccgg
      781 ggtctgtcgc ataacctgca tcttgcaatg cttgtgcggc ttcctgatag ttggtggccg
      841 taatcacttt ttcatacagc gcaggattcc aatctactcc ttggacgaac agttgtgtat
      901 ggtcatccat ggactgttcc catgaatcat acactttgaa gtctccttgg atagttatcc
      961 attcttcgtt aacaaattcc tttgtttcca ggcttacttt cttctgatcc ccataagcct
     1021 tgatcccgaa aagattattg tatttgctag ccaaggtact ttttccccaa tttgattcta
     1081 atatagcttg tcctaaaatg atactaggaa gcactccata accatcttgt agttcttggg
     1141 catgcggaac aagccgttca ataaattgct gatgggattg cgcttcattt tcttgctgat
     1201 tatcagtaaa aggagaagac agattcttca aggaaaaaac aaaggctaag agtatcactg
     1261 ctacaccggc aaccactgct ggccaacgga tattcttgcg cttttgcttt ttccactttt
     1321 ttttcgccat gatcaattcc tacttttcat ttaattcatt cagatattct tctagcgtca
     1381 attggtgttt ggtgatatac tcagcgtttt ctttaccgac ataacgtaag tgccaaggtt
     1441 catatgtgat cttagttata tcttcgtgtc cttttggata acgaacgata aatccatact
     1501 gcgcagcatt atctgcgatc catttagctc caggctgatc tccgtaactt gcatccaata
     1561 cagtagaagg ataactgttg taccagtttt gatcgacgac atcgactgcc agacctgtgt
     1621 ggtgttcgct gtatcctggc tccgtaatcg tttctttagt aatctttgtc gcctcctctt
     1681 ctgatacacc ttgacgactc atcacatctt ggacattttg ttcgaaaact tgttgttggg
     1741 atgatacaga ccggtaagct gagaccatca ctaatggaaa tccagctgct tcagcagcct
     1801 tggcaaatgc ttcatattct ggagcaatgc gtttgtcgat caagtatccg ttacttaatg
     1861 atgccaattg agtagactca tcaatttctt tttctaattt gtgatctgga ccaaccaaaa
     1921 ctagcttcca atcgtctgtt ttaacatctg gcaattgttt ggacgtacga tcttttgttt
     1981 ctttgtcctt taccttgctg ctggttgttt gactgttctt ttctttacta gcagttgttt
     2041 tggtgcttgt tcgttcgact gcttgattgc cggcttgaac atgcgaatca tcatcgctaa
     2101 aaataacata gcccattgct gcgatcataa tcacaactgc tccaaatcct aaaaatttat
     2161 tcacttgaaa aatcctttcg ttgttcttca cgttccccat tcgcctcatg aacgtaagtt
     2221 tcttccagat tttcattcac ccaatcgaga agttcgattt tttctccttc gatctgtttt
     2281 tgaacatctg ctggcagacg aaaattcaaa atatcatcat agccccattc atcatattga
     2341 atacttactt tcaagtcaag gtatctacca gcctgctgat tatttttcaa agggatcagc
     2401 tcgacttttg ctgctttgct gctaagccat ttttgcgcga tgcgtgtttt gatttgcttg
     2461 tactctgcaa cggcaacgtt tcgtttttcg ggaaaaataa tcgtttgacg caaaatcttt
     2521 tgcgttagca tccattcata atcagtgaaa agatttttta ctttctgcat cgcttcagat
     2581 ggcagatttt tctcgccatc tttccatttt tgccattgtt ctggactgat cagcaagtat
     2641 tcatctaaaa aatttttttc agtttcaaac tgttctaata atacactcat aataagatca
     2701 atatatactt gatgcacgtt tatcccctcc ttttaactat tctacttaag ttttgatcaa
     2761 aaagcacctc ttaaatcgct gctttcattt tttttaatgt ttcaagtcct ctcctcttta
     2821 ttcttcgtga tttttgttat aataatagac agacaagaaa ctcaatccaa ctatgaagga
     2881 gcgttttcag atgaaaaaat atcaatgggg aatcgttggt cttggtacca tcgcacatga
     2941 gtttgccgaa agcttcaatc aagagacgag cgaactaaca gcagttgctt ccagaacttc
     3001 agaaaaagcg gaaaacttcg ctcaccgtta caatattcca aaagcttacg gaagctatca
     3061 agaaatgtta gacgatgctg aaatcgacat cgtgtacatt gctgtaccaa atagacagca
     3121 tatcgaccat atcttggcag cattggaagc aggcaaacac gttctatgtg aaaaagccat
     3181 cacgatgaat aaaaaagaac tggctgacgc tatgcgctta gcagaagaaa agaatttgat
     3241 cttagcagaa gcgatgacaa tcttcaacat gccactttat cagcagttac gctcaataat
     3301 ggatacagga aaactggggg ctttaaaaat gatccaagca cctttcggca gttacaaaga
     3361 accagaccct aaaaaccggt tcttcaatcc agaattagct ggaggagctc tgttggatat
     3421 cggtacgtat gctgtatctt tcgctcgttt ctttttgagc tctcaacctg aagtagttgc
     3481 ctctacaatg gttccttttg aaacaggcgt ggacgaacaa tccgtcacta tcttgcgtaa
     3541 caaagaaaat gaacttgctg ctgtcagctt gacttttcag gcaaaaatgc caaaagtcgg
     3601 tatcgttgcc tttgagaacg gttatgtgac gattgctgat tacccgcgtg ctgatcgtgc
     3661 ggagatctta tttacagatg gtacaaagga attcatcgaa agcgggaata catctgaagc
     3721 aatgaattac gaaataaaga atatggtaca catgattgaa ggtgacttgc ccaatcgctc
     3781 tctcttcttg acaaaagatg tcatcgaaat cttggatcaa atgcaagttc tatggaaaaa
     3841 tatgtaattt taaaaggttg tgaaaaagct gttctgcatc aagtaataag aacagccaaa
     3901 caaaaatagc tcctcctatt tttcgtttgg ctggacttat taccgcagag gaaagctttt
     3961 gaacaccgtt taagaaagag gttgtgagcc taccgttcag ctccgagtca caaggagcaa
     4021 tttcaaaaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttgaca
     4081 ggagaacacc gtttaaagaa gaggttgtga aatcagcttt ttgacctgaa tattagctga
     4141 attcacaacc tctatttttg gattttttgt tgggagaatt ctgccttgat ttcaataaaa
     4201 cttttaaaag actgcaaaaa ctggaacaat tctgctcgat cctcgaattc agggcgacta
     4261 gtcggcagag gcatttgccg atacaataca taaacttctt caatacgtgt taaaatttgt
     4321 ctgccatcat ttgactctga aaatgtttct gcagtataaa tcaataaacc atagatatgt
     4381 tttccataat aagctggttg ctggattctc tctagatttt ccagcatgtc tttaatcaca
     4441 ttggcctgtg ctcttctcat agagaagtaa gtttcgtagt atagcggctg tctgagccag
     4501 tagttttctt gatgttctct ggcatcttct tggctttcgc gaatgaatgt cagtaaatgt
     4561 tcgcatttga tctgcacatc ttctttattt tctgataaaa gaaattctgc catttgtctc
     4621 aaaatatttc gaaattcttt ttcgatctgt atttggtttt ccttcagctg cttcgtacga
     4681 tctggcatgt aaacatttgc aagcaaagca aatactaatc caatcgccat taatcccgct
     4741 tcattgccga tcagctgcca agacatgttt tcctccacta aataatgagt gaccaaaacc
     4801 gaatttacta ctatcccttc ggttaatttg aagcgagagg caagcgggat gaacaggaat
     4861 aaaaaaagac tgaagccaaa aatagtatac ccaacagcaa aaaaactgaa cagtgctgtt
     4921 gccgtagcta atataaaggc tgcgattcga ttcatgcccg tacgcaatgt agagcgcttg
     4981 gtatttccta cacttaataa tgcaatgatc cctgcagctg gccaatacaa cagcgataag
     5041 ctacccgctg tgaccatcga aaagaagaca ctgatcactg ttttgactgt tcgcattcct
     5101 atacgcattt acttccccct tttttatttt aattatactt gaataatgaa aaactagcta
     5161 tcagacaaaa gtttaggtat gatagtaaaa agaccaaaaa ggagaatctc tatgcaattt
     5221 ggccgttttc gactaggtat gcgtacgatc aaaagtgcct tagctgtttt tttatgtatc
     5281 ttgttttttc atttgactca acgaggaatc ccgatgattg ctgcattatc tgctgttttt
     5341 tctttgcgtc aggacttgac tacaaccgtt tcttttggaa agtctaggat catcggcaat
     5401 acattaggtg gtacattagc tatcatttat ttttttgtca aaagctattt tcacaatgat
     5461 tttttggtag aattgatctt gcttcctatt ctagttatta ttgtgatcgt cgtgtcagat
     5521 ggtattaaca ataattccgg tatcatttcc gcaatagcta cgttgttgct gattgcgttg
     5581 agcatccctc aaggcgaatc cgctttgtat gctatccaac gtgtactaga tacttttata
     5641 gggacattca ttgcaatcgg tatcaatttc tttcttcgtc ctcctgaaac agaaaagaag
     5701 gaagaactat cagaagattt ggtcgaactc caaaagaaag aacgattgct aagaacaaat
     5761 ttacaagaga tagaagctaa gatccaaaaa caaaagaaaa atagcgagga ctaattttct
     5821 tttgcaataa aataaaaaaa tggagagaag aactttaaaa agtcttcctc catttttgat
     5881 tgaacggtga agtgtactac tttattcttc cttcatcgag ttttgttctg cctcttttgg
     5941 cgcttcatac atatttactt ggctagtagt cccacgtgtc gacaaattct ctacgatttc
     6001 cttcaagtca agtcctgttg tcgcttttag tgtttcttga gtagaagaaa gcaaatttgt
     6061 ggcataattt gtcactcggt tcgctccact ggtttctcct gaactgcttc ctgtatcgac
     6121 aacagagatt ttttcgatat ttcctagcgg ctgtgctgct tcgcgcatca attgcggtag
     6181 catatcgata accatactca agacagctgc ttcgccatat tccttgaagg cattggcgat
     6241 cttttgtttt gcttcggctt ctgcttttcc ttttgctagt gctgcttcgg cttctgcttg
     6301 tccagctaaa cgtgtcttat tggcttccgc ttctgccagt gcttccacac ggaatcgttc
     6361 tgcttcggct tcagtcactt ctttgacttt ttgagcttgt gcttcttgtt ctttagcgta
     6421 ccgatcggca tctgcttttt tcttcacttc cgaatcatat tgcttttcac gacgtgtgat
     6481 ttctttttct tccagttcga tttgtttttg acgttctacg attttaatct gcatttcctg
     6541 ttcgattact tgttgttgtg ctcgggcact ttctaaattg taggcttggt ctgcttttgc
     6601 tttagcaaca tcttgttctt gtttgtaggt tgctaatttc agttcttttt cttttaatga
     6661 ttctgcgatc tctgtttgtc gctgtaattc agctgcttgt gattcttttt ctgcttgagc
     6721 ttttttgata cgcgtttctt ttagagcttc cgcttctgct atatctgcat ctcttttgac
     6781 ttgggcgatt cttggtttcc ctaaagagtc aagataaccg tttttgtctc tgacctcttt
     6841 gatagtgaaa gaaacgatga tcaaccccat ttttgcaagg tctacagaag cgacttcttg
     6901 tacgctttga ctgaacttat cgcgattttg atagatttct tctacagtca tagaaccaag
     6961 aatcgagcgc aagtgtcctt ctaatacttc tcttgcttca ttttccagtt cttctcttgt
     7021 cttgcctaaa aactgttctg ctgctgtagc aatctcttct acagatgaac cgattttgat
     7081 gatcgaagta ccatcacaca tcaccggtac gccttgttcc gtatacactt caggggtgga
     7141 gacgtccaat ttactcgata atagactgat ccgattcgaa cgttgaaaaa ctggcaagac
     7201 gaatgcgcca cctccacgca caattttgat tttgttattg ctttcatcaa tgtgcacatt
     7261 tttgcttcct aaataacttc cactgatgat caacgcttca tccggttttg ctgtctggta
     7321 cttcgctaca aagacgatca gcaacatcag taaaatcaaa gctgcgattg cgatcgcgat
     7381 aaaaacaact ggtatttcca tttaacacac gctcctttaa gcttttatca tgctttcata
     7441 aggcatgaca taacagattc tttccttgat ctcaatgatc aatactttcg ttccccgctc
     7501 agctgtctgt tcttgggggc tgtaaaaaca agctggacga ctaatggaac cggtaacact
     7561 tttcaactga atttctccca tacctcgtac agggatcggt gtgatcacaa cagctacttg
     7621 tccttccaga gttttttcag aagacgacat cgttgattcg gcatgtttca tcggcatcaa
     7681 tatatagaaa ttaagcaaaa ataccaacac tatcgatatg cctccactag caataaataa
     7741 aaataaagat gattgatctg ttaaacgctc acctagaaaa ccaaataagc ttgtgaaagt
     7801 taaccaaggg ataataagca tcggatcaag cgggccatca aaatcgaata catctccaaa
     7861 aataatcaat aggactgcca atcctgcaca aatcagcaat gtataccaat aaatcgtctc
     7921 aagtgcgatt ccccctatca tatacacgcc tccttccatt tctacgtcta tcataccaat
     7981 gtttgaaaat tctgtatagc ttcttttacc gactcagtgg tgttttttat aggaaggttg
     8041 tgtttatcgt tgacaatttg ttaaattttt gttttcatgt taaaattttc acaataaatt
     8101 ctttcgaggt agcctatgtt tccttttttt aagaaaaaac cattaaagct ccagaacacg
     8161 atcatccttg tcgtttgttt ctccacattc gtttctttga ttgtttctgc catattgatc
     8221 aggaatttta ttctttcgat gaaccgatct agtgtgtcag ataaaatctc tagcattgct
     8281 aaaatcgttg ccaatgataa actcatccaa aaaaagctgc agactggtga cccgacacat
     8341 gcgattcaag gaataacaaa tgaaatcatg attgcatcga atttagattt tatcgttgtc
     8401 atggaccctg aaggcattcg atattctcac gcagacccaa gttacatcgg tcttcctttc
     8461 tcaagtcatg aagatgtgaa aaaagtgatt ggaggacaag aatttttctc tgaaaaagaa
     8521 ggaatgttag ggttcggctt ccgctatttc gtccctattt attatgatca agagattatt
     8581 ggtgcagttt gtgttggctt aacaaacaac acgattgaca atcaagtcaa agatggacaa
     8641 aaaatgattg ttttttcatt gattattgga cttagcgtag gcatcatagg cgccgttttt
     8701 cttgcccaaa aaatgaaaaa agtactgctt ggacttgaac cacaagaaat agcagaacag
     8761 ttaagtgaaa aaacgattat cgaaaatgaa gtagatgaag gaatcttagc catctcttct
     8821 gataaaacta tcctcttgat caatacacct gcaaaaaaca ttttctacca aacagagcag
     8881 ctattggatt tcgaagtagg aaaaaaatca gtgataatct atatgacgtt ttgtttaaag
     8941 agacgattga gcatcaaacg accgttcgga ctcaatccat gtatttaaat gggatagaaa
     9001 ctatttctag cgttacacct ctttttagca atgaccgttt tttaggagca gtcgcaactt
     9061 tacgaaatcg atcagaagta atgaaattaa tggaggagct tggggggacg aaacaatata
     9121 taaactccat gagagctcaa acccatgaat tcatgaataa acttcatgtc atttctggtt
     9181 tgattgattt gaagaagtat gaagaagtca cccattttat ccagcagcta aatcaaaatt
     9241 ataaaaaaga gattggccaa gtctcaagtc tgatcaaagt acctgcaatt gccggttttt
     9301 tattaggcaa aataaacgaa gccaaagaac aatctgttga aatgctgtta gaaagcgatt
     9361 cttttatccc taaaatggag atggatgact ccatccattc acttttgcaa gtgttaggga
     9421 acttacttga taatgcaaaa gaagccgtgc tacaaaaaca tgaaagaaac ggacaggtcc
     9481 ggattcattt aaactatgac acagaagctg aagtattcat cgtgaccgtc tgcgatgacg
     9541 gtgtcgggat atcagaagaa atctcagaaa aaatatttac gctaggtttt tcgacgaagg
     9601 gaatcaatcg tgggtttgga ttgaatctca tccattcaat cgtcaaacgc cacggtggat
     9661 ttttagaatt ttccaaacaa acaaatggcg gtacaatcgt ctatctagaa ttaccaaaaa
     9721 aggaagatca aaatgatgac aaatgtcctg ataatcgaag atgatccaat ggttgcagaa
     9781 ttgaatcgta cttttgtgga aagcatccct aatatgaacg taatcgaaag tttcagaaat
     9841 gtagaagaag gaaaaaaata tttcagacaa aaaaacgcag atctgctgct gcttgatgta
     9901 tacatgcctg gcgaaagtgg tatccatttt ttatcttggc ttagacagca aggaaatgat
     9961 atcccagtga ttttgatcac tgctgcagat gatatcgaaa ccataaagaa tgtgatccgc
    10021 tacggtgcct tagattattt gatcaaaccg ttcactttgc aacgttttca gctggcgatc
    10081 gaaaagtatc ttgctttctc tcagacaatc caaacgactg aaaaagccga tcagaaattg
    10141 atcgatcaag tattcaacca caccactccc attcacgaaa taccatcatt catcgatttg
    10201 cctaaaggtc tgtcaaaact gactttaaaa aaaataagtg catttattct aaaagaagat
    10261 actatttttt caacaaaaga actggctcaa aaaagctcac tgtcacgtat atccgtcaag
    10321 aaatatttga attttttagt agaacaagat atattgaacg aaagaatcaa atatttggaa
    10381 atcggccggc cgctaacctg ttatgaattg acaaagaatg ggcggaaaaa gctcacagat
    10441 tactgttgag tcatcgaatt atcccataca aaatagtcca agtatacaga agtaacaact
    10501 gtttacttgg actattttta aacattttat tgacgaatat ccatgttttc ttatcttaat
    10561 tgacgggctt taggaagaga tacctcattt ttcgtttttc cagtttctat tatttcacga
    10621 aagttctcga aacttgtcga aatcatattt gataatgcct catctgtatt tgaacctaca
    10681 tgcggggtta caagaactct agggtacatt tctactaatt gctggatagc agggtctgga
    10741 atcgtctccc atggcttgaa ggatcggaaa aaaacctctg tttcatttgc aaaaacatcg
    10801 gttgcaaaac cagctaaatg attgcttttc aaagctctta aaatagcttc attatcttga
    10861 agctctccac gggctgtatt aatcaagatg ctaccttttt tcatttgagc taaaaatcct
    10921 tcattgatca tttgatcgtt ttcacctggg atatgaggta catgaatact gacaatatcg
    10981 cttttggcta ataactcttc aagcgagtgg aacgtcaata cttttttagc agcttctgtc
    11041 tgatgaatat cgtagccgat cactttggct cctagtccct taaacaaaac agcttccgtc
    11101 aaccctatcc tgcctgttcc tatgatccct actgtgcaat ttctgatttc acgactaaac
    11161 atttgctcat ccactcgaaa atctttgaaa gatgttcgga tcgtcgtata cgcagtattt
    11221 ctcaaaagca tcatggcaaa agtcaaagat aactctgcta tcgcatttgg cgaatacgat
    11281 ggtacacggg ctactgtcat accaaaatca gctgccgctt gtagatcgat atgattgact
    11341 cccacagtcc gtgtaaaaac ataacgaatc ccatattcct gcatttttgc aagattggtc
    11401 tcatctgcta tacaatttcc cctcaacaat acagcatcat ggtcctttgc tgacacgata
    11461 ttgtcatgtg tcaacagttc ttcataaaga ctgagatcat aatggtaaat attcaatttt
    11521 tcaaaaaaat ctatctcgtt cggacgaaca ccgtaacatg cgattctcat actttcttcc
    11581 tccatttctt atgaaaataa acctatgcca tgaatcattt gtaatacaac gatccataca
    11641 ggtgtcagta ccacagcaaa aatagttgac agtaaggatg cattggaggc taaaagtgcc
    11701 tccctatcaa aactgatagc ataggctgct gccactgttg cagctggtgt agccatcatg
    11761 ataacgattg ttgccagtgc ttcaaaattg actggtagaa tattcgttgc cgtcaaaact
    11821 gctagaatca cgatattcaa tgcaggtaca aataccactt tgactagact gtaataccat
    11881 gaagtttttt cagatgcagc ttttttgaag cttacttcac ctaatgttgc gccgattgct
    11941 agccacgcca atggtgaact taaaccagct aaataatcca tcggctgaaa tagccacggt
    12001 gcagtctggt caattcgcaa aaacgctact tggcttatct ctccttctgc acctgtaact
    12061 gacacttgtg gcagataccc ttggaacagc caaatgaaaa ggccggcaaa agtagcgata
    12121 atgattggat tgacgaacat cgctttgata tttttagctt ccatcttcaa gccactcatt
    12181 tttatgtatc cataagaata caaaaagatt cggtagccaa tattgaaaat tgaggaatac
    12241 atcacgccga caggaccata aatcgcactg acgataggcg ttccgaaaaa ggtcgtagaa
    12301 ccaaagatcg tcaggacacg caacgttgtt tgcttatccc ctttatagct taagaaaaaa
    12361 ggttttgaaa ctagaataag aataatataa ataactaatc cccaaatcaa gacattgatt
    12421 ccttgcatca gtaattctgt attgatatct tgcatgaaag ctcgaaatgc cagtgctggc
    12481 aaagccactg ttaagacgac tttcgataga atttttccaa cagattcaga aaaaatcccc
    12541 ttttttctac aaacaaaccc taataatata ataaaaactg ttgaagtgat tgcactgaca
    12601 atcgacatat ctgtcaaagt cgatcgaaaa atgtcaaata agttcatctt tctcctccta
    12661 attatgttca tttattcaca ataaaaaaag cttttatttt gctaatacgt attaacattt
    12721 ttaattttat ctttacattg ttacttattg aacaatagga aattaaagaa acttttgaaa
    12781 cttatgtaaa gtgattttta ctagaacaca aaaaaaacct taaaaccaaa cttaagaagt
    12841 ttagttttaa ggttaactta aattatatta tgcgtggaaa cgttccacgc catctagata
    12901 agttgcttcc aatgtcatat cagggttcaa tacgataaag tctgcatcgc gtccttgagc
    12961 gatttttcca catgtatcat cgattttaca gctgattgct ggaatcagac tagccatcat
    13021 gactgcttgt tctggtgttg ctaatcccca gtctacaaca tttttaattg cttctttcaa
    13081 tttcaatata cttccagcta agttgccaga ttctagacgt gctgttcctt cttttactac
    13141 tactggaaat tcgcctaaat tgtaatttcc atcaggcatc ccaccggcca tcatacagtc
    13201 tgtaattaat gcgacatgat catgtcctgc tttttccatt aggattcccg cagcatttgg
    13261 atgtacatga tggccatcac aaatcaattc agaaaagaca tgttctaaag ataataacgc
    13321 acccaccata cctggttcgc gatgattcaa tccacgcata ccattgaaag catggacaaa
    13381 tacacttgcg cctgcttcaa cagctttttg cgcttcttct agtgtagcat tactgtgtcc
    13441 tagagaaaca actactcctt cttcagtcac ttgtttgaca aactcttcta caccttgacg
    13501 ttccggtgct aaagcaattt ttttgattaa accacctgaa gcttcttgcc attcatggaa
    13561 agtatccaaa tcaggatccc cgaaataact tgggttttgt gcccctttgt gttcttctgt
    13621 gaagaaagga ccttcaaaat agattccttt gattttagct cctggtgctt cctgatacat
    13681 tttgccgatt gtctcagcta catcttttaa acgttctttg cttgacgtca atgttgttgg
    13741 taaaaatgaa gtcactccac aagataacag accttcagac atcactttga tgccttctgc
    13801 atcattatcc attacatcat gattcatata gccgtgaata tgtgtatcta ccaaaccagg
    13861 agcaatccat ttgccgcttt ggtcaatgat gttgacttct ccctcaggta gttctttggt
    13921 gtattcacca aaaagtccat cggtaatttc aagatagcct gcatgtttga cacctgacgc
    13981 taaaaagaat ttgtcagcat agataaaagt tctcattcta ttctctccct ttgtttttct
    14041 acctctaaag tactcttatt tagagaagaa gtcaagaatg gtctacacca tttacaaatt
    14101 ttttgaaatt tgtttcacag cttgtgctaa gccttcatag aatgctgctc tttctggttc
    14161 ttctttacgc ttgtatatta agcttttaag cacaaataaa tcattgaggt aatagtagct
    14221 attcttctct tgagcccaat agattccttg attcacctgt tctaacgctt cgtcgatttc
    14281 attttgatgg aataagaaat ttccataatt ataaaaaatt tgcgaaaatt cactttttga
    14341 tcgttcatca gctgattgat gcagcagttg gatgcttcga ctcaaatagt agcgtgcttc
    14401 agccgttttt cctgccacac catatatttt tccgatacaa ctaatcagtt gtatttctgt
    14461 gtcagaaaca tggattcttt ctttttggct agagtagctt aatgcttctt tcaaataata
    14521 aagggactga gagatatttt gacgcaacgt gaattcgcaa acaccgagat aataataata
    14581 gcgttgaaag tcagttgctt gatacagatt ttcagaaata tcagaagatt ttagtacttg
    14641 ttctaacttc cgataatcac gtttttggaa acaactatcc aacagttcaa ataatttatc
    14701 gtttgtccga gtagtttttc gagagagatt catcacatga tcaatcgtta cccctagccg
    14761 ttgacaaatc tgcatcatca ccaatacatt cggcagttcc tcattatttt cgatccgact
    14821 taatacactt tgtgaacaaa tatcatgcga aagcattttt tgcgtcattt tttgttcttt
    14881 tcgaatctct ttaatgatcg ttccaaagga ctcgattaac gtttccataa gtatcctccc
    14941 caaaatatgc gtattcgcat tctattcgta ttttacttta ggaagtcgca aacttcaaga
    15001 aaagacttgc aactaaataa tatactttag ttatttaaga aaactccact agaaagagag
    15061 cctcagtgtg tttgtctgtg gccctcctac tgaaaaattt ggtttttaaa atcatttttg
    15121 gcgataggtt gctaggaatt ctctcatttt cttagctgtt tgtttcaaat catccatttt
    15181 aggaagataa acgattcgaa aatgatctgg ctggttccaa ttaaatccac caccatgtac
    15241 aagtagaata tgatgttcat gtaaaaagtc caaaacgaat ttttcatcat ccaaaatatt
    15301 gaatcgcttt gtatcaattt ttgggaatat ataaaaagca gcttttggtt ttacggctga
    15361 aagaccagga atatcattga ttgcattata gatatattct ctttgttcat agatccttcc
    15421 gcctggcagg agcagctcat cgacactttg ataaccgcct agcgcggttt ggataatttg
    15481 ctgagacaat acattggaac acaaacgcat ggaggacaac atattcagcc cttctatata
    15541 gcctttgacg tgtgacttat ctccacttag gaccatccag cctactcgaa atcctgctac
    15601 acgatgagat ttggatagac cgttcagcgt aacaacgaac aaatcaggcg ctaatgtagc
    15661 aatcggaata tgttctagac catccatcac taagcgatca tagatttcgt cggaataaat
    15721 aatcaggtta ttttgtcgag ctacttcaac gatttcttct aataattctt ttggataaag
    15781 tgccccagta ggattattag gattaatgat aacaatagct tttgtccgac tcgttatttt
    15841 tgatttgata tcatcaatat caggatacca ttctgcctct tcatcgcaaa tataatgaac
    15901 aggtgtgcct ccagctaatg caatagaagc cgtccacaac ggatagtccg gcattggaac
    15961 cagtacttca tctccattgt ccagcaaccc ctgcatacac atcgtgatca attcgctcac
    16021 tccgttgccg gtgtagatat cattgatcgt cacattcgga aaatgtttca gttggcaata
    16081 ttgctcaatt gcttttctag cagaaaagat ccccttggaa tctgagtagc cttctgagtc
    16141 acgggcattc atgatcaaat cacgaatgac ttcgtttggt gcttcaaatc caaaaggtgc
    16201 gggatttccc gtgttcaatt ttaaaatact aatgccctct tcttgcatcc gctccgcttc
    16261 ttctagaacg ggaccgcgaa catcgtaact gacaccttct aatttgttgg atttttcaaa
    16321 ttctctcatc acttagccaa tccctcattt caaaaagtta gaactttcca aattttttgt
    16381 tatttactat ttcaatatca tactccatcc tagaaaattt tgccacttat ttaggaaaaa
    16441 cgtaagtatt aaaaaaacac aaacaagcgt tgagaactta attgtcatga tagtcattcc
    16501 atagattcgc tgcccaatcc attgcaattc cacaaatgat tcctagcata aaaccaagca
    16561 aaaaacgtcc gaatgcaagt ccaatcaata cacctaagat cattcccagt cctgaaaatt
    16621 ctccgtcata tttctccatc ttaataagtc ctcccatttt tgagcttgac aactatgtaa
    16681 aacctcgcta tcattagtgt gttattatta cgcagatgtg ttggaattgg cagacaagca
    16741 tgattgaggg tcatgtgagc gttagctcgt gtgggttcga gtcccatcat ctgcactaca
    16801 actcgtgaag ttaattttgc ttcacgagtt tttttgtttg aacgtttctt tatgccatta
    16861 tatacatatc actgtatcct ttacaaaaag aacgtacaat catgtaaaca gcctgaggtg
    16921 agtatatgaa ggtcggaaac aagctactcg tagaaacttg caagtgttaa aacaattaat
    16981 cgaaaaacga gtaaaatccc tcacctaata ctaaagcgag ggattttttg tatattatct
    17041 gtttatcacc gttattataa aggtacaaat accaagcacg gttaatccaa attgcataaa
    17101 ttcatttttt tgtacactca tgcttttcat tagctcttta actgccatta gtactaagat
    17161 ggcgataaca acataaagta tatagtacgt ccgcattccg gaagcccata ctgtgggaga
    17221 aaatcccata attaaccttg aacaaaatcc cattatcatc aaaataacta aaaaaataga
    17281 agttttctta ttgtcaaaac ttaaataaat tccaacaatt aaacatagta ataatgccaa
    17341 gactactaaa gtagctatcc aagtacctgg ataaaaaagt gacagtttcg ttcctaactc
    17401 tgtaaagaga ttattcaggt tactactact ccaaatcatt gcccttttat ttccattgac
    17461 gtaagtaaag ctttgaccca ttgtattacc aaaataaata atcaggttta agaaaaacgg
    17521 taatgcagtc aatatacgca cataatagtt ttgacatttc ctatatgtta gaaggaaaat
    17581 taagaaaaat agcaataaaa ataagatatt catgtctaaa aaaaacggct ttccaaatga
    17641 tgaaatacct aaatctaact tattaagaaa gttgaaattt ttatattcag gaaaccattt
    17701 attaatttca tgtgcagcac gtaatgcatt ccctggagtt gtcaaagaga aaattaattc
    17761 tgctaagctt attattgaaa atactgataa cttataatta tatcgtccat tgacaatcaa
    17821 atataaacta actatacttg ttagaacaaa aaaacaggcg ttgacttgtt cttgattagt
    17881 taaaaatatc aataaaggaa tacttaccca atatattttt ctatttattt cttctcctct
    17941 taagagttga aaaaacggat aaaaagttag taaactaaat gctactggcc actgatagtt
    18001 caaggtggtt gctctccaac cggtttcccc cattactgtc aatggtatta aacagtatat
    18061 agagcaaacc aataataaat ttttaacatt tattttctca aaaacata
//
LOCUS       DACDAF010000055        18106 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.055, whole genome shotgun sequence.
ACCESSION   DACDAF010000055 DACDAF010000000
VERSION     DACDAF010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18106)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18106)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18106
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.055"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(63..1541)
                     /locus_tag="IVZ69_001784"
     CDS             complement(63..1541)
                     /locus_tag="IVZ69_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP8183863.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(1839..2774)
                     /gene="murB"
                     /locus_tag="IVZ69_001785"
     CDS             complement(1839..2774)
                     /gene="murB"
                     /locus_tag="IVZ69_001785"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HAP8183864.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(2847..3767)
                     /locus_tag="IVZ69_001786"
     CDS             complement(2847..3767)
                     /locus_tag="IVZ69_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP8183865.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            3880..4632
                     /gene="xth"
                     /locus_tag="IVZ69_001787"
     CDS             3880..4632
                     /gene="xth"
                     /locus_tag="IVZ69_001787"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HAP8183866.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            5618..6151
                     /locus_tag="IVZ69_001788"
     CDS             5618..6151
                     /locus_tag="IVZ69_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HAP8183867.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(6641..7165)
                     /locus_tag="IVZ69_001789"
     CDS             complement(6641..7165)
                     /locus_tag="IVZ69_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8183868.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(7158..7631)
                     /gene="tsaE"
                     /locus_tag="IVZ69_001790"
     CDS             complement(7158..7631)
                     /gene="tsaE"
                     /locus_tag="IVZ69_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HAP8183869.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(7754..8734)
                     /gene="pta"
                     /locus_tag="IVZ69_001791"
     CDS             complement(7754..8734)
                     /gene="pta"
                     /locus_tag="IVZ69_001791"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HAP8183870.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(8887..9567)
                     /locus_tag="IVZ69_001792"
     CDS             complement(8887..9567)
                     /locus_tag="IVZ69_001792"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HAP8183871.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            9693..10562
                     /locus_tag="IVZ69_001793"
     CDS             9693..10562
                     /locus_tag="IVZ69_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP8183872.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            10588..11103
                     /locus_tag="IVZ69_001794"
     CDS             10588..11103
                     /locus_tag="IVZ69_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183873.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(11150..11713)
                     /locus_tag="IVZ69_001795"
     CDS             complement(11150..11713)
                     /locus_tag="IVZ69_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8183874.1"
                     /translation="MIRFARKEDAPEIAPLILVILKDMELPFLKQTGEQKTLEILEEA
                     ITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKYQLDASTRLFI
                     DKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLSVDEKNPKAKK
                     LYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(11768..11947)
                     /locus_tag="IVZ69_001796"
     CDS             complement(11768..11947)
                     /locus_tag="IVZ69_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183875.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(12024..12533)
                     /locus_tag="IVZ69_001797"
     CDS             complement(12024..12533)
                     /locus_tag="IVZ69_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183876.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(12629..13009)
                     /locus_tag="IVZ69_001798"
     CDS             complement(12629..13009)
                     /locus_tag="IVZ69_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP8183877.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            13339..14088
                     /locus_tag="IVZ69_001799"
     CDS             13339..14088
                     /locus_tag="IVZ69_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HAP8183878.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(14272..15549)
                     /locus_tag="IVZ69_001800"
     CDS             complement(14272..15549)
                     /locus_tag="IVZ69_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183879.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(15628..16272)
                     /gene="pcp"
                     /locus_tag="IVZ69_001801"
     CDS             complement(15628..16272)
                     /gene="pcp"
                     /locus_tag="IVZ69_001801"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HAP8183880.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(16471..17415)
                     /locus_tag="IVZ69_001802"
     CDS             complement(16471..17415)
                     /locus_tag="IVZ69_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HAP8183881.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(17417..18103)
                     /locus_tag="IVZ69_001803"
     CDS             complement(17417..18103)
                     /locus_tag="IVZ69_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HAP8183882.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
BASE COUNT         5266 a         3697 c         3146 g         5997 t
ORIGIN      
        1 ttctttgaaa aaaacataaa tcagctaata aatatgtgag acaaagctgc catccataaa
       61 tactagctga ttttttcagt taaatgtcta tttttttctc tgatgatggt atttccaaaa
      121 tattcccagt catctggagt cggtggattt ttccaaatta tctgttcttt attaaatttt
      181 tcaagtaaac aatcagataa ataaatattc gtacgagaag tgattcgact ctcaatcaca
      241 atattgtaat ttttaaatcc tttcacttga gaaataatgt aatcggtata agcagatcct
      301 tgcgaaaaat caatacagac atgaatcggt gcttcaaaat atgataccgg acaaataccg
      361 accaataaaa agagataatc ataaaataag cgaatcatga aacgttcatc ttttcccaag
      421 aaatagcgtt tattctcttg tatgaccttt tggattgctg tactgaatat tggatacgtc
      481 tcgaagaaaa actgtagctg ctttttagac gtaaagctag tcatctcaaa gtcgaatatc
      541 caattttttc gattgacatg catcataccc atacgaagtt cttttcgtat atatagtctt
      601 tcttcttcag agatttcaat cgaaaatggt aattgatcaa tcaattccac tgacattttt
      661 tgactaatca tgtggatatc atgaaaatga gcttccgcaa gtccaaatgc gccatctaat
      721 tcaaattctt cttccgtgat caaaaacaac atgatataag aaatctcatc aatgatctgc
      781 tctttaggga tatgaagaaa agaaatatgt gataaatcct tgatgatctt cattccttct
      841 gagctcttaa agtattcatc tgaaaagaaa cgttttccga ttggttgatt cccataggcc
      901 ctcaacaaac taatagtggt tagcaaattg aatttgattc gttttgttgc agacagtttt
      961 aaattgaaca gatattcaaa atattgcacg atactctttg cttcattcat gacgctttct
     1021 ctaaatggca tagaaaaacc attaaagacc ccgaaatata ccccaaataa tacgttccgt
     1081 atgtttattt cttccccaac taatatgttt ttctttaact ttatttgatg ctgttcaaga
     1141 aaagagacta attctcttct ttttacatag gctcttgata tgcttaaaaa atgattctct
     1201 gcaaattttt cgatcgttac ttttgaatcc acgatctccg ttaacagtcg agcaattttt
     1261 gatcgttgaa agtagattct tcttaaattt ttgatatccg tcaaattcag acgttcgaca
     1321 tggatctctg cttcttctga aatttggatc tctggctttg ttttgaattc agtaaattct
     1381 ttatttaatt ctatgatata atttcttgtt ttaaatttag acaaacctaa tgtttcatat
     1441 aacttaggca gcactacata attctttttc tcaaattcta aatatctagc tagcagcagt
     1501 ttttctctat cttcctcttc tataaggtaa tccaacttca tatcctacac ctcaaaaaat
     1561 gcctcatacc aattacttga tatgcagatg aaagttcatc ttttcaccta tactgatttt
     1621 atgatggatt atgcttgttt tttcatcagt tattctcatt ttttatcttt tttttgagaa
     1681 tattgcaaaa aatggaaaaa tttatgagga aatattctat attttttgtt ttattgtgtt
     1741 aaaatgtaca agatttgcgc catttgcgta aacaaccaca aaaaagagca ggacggccac
     1801 cgtcctgctc ttttacttat tttaagttcc attacttatt aattggctaa acttctgctt
     1861 gtttctgata ttgcttgttt ttctccaatg atccgcactt ctgtttctaa agacacatca
     1921 aatttttctt tgattacttc ttggatgtgc gcaatcaatt caatataatc tgtcgctgtc
     1981 gcatgatcga tattgacgat gaatccagca tgtttttcag agacttgtgc accgccccat
     2041 ttcaggcctt gcaatcctgc ttgttggatc agctgacctg tatagtgtcc tactgggcgc
     2101 ttaaagacac ttccgcatga agggtattct aatggctgtt ttgattgacg caattcggtc
     2161 aactcatcca ttcttgcttt gattgcttca taatcccctg tttgcaaact gaatcgagct
     2221 tccaatacga tagcacgtaa ttcttggact ttactgtgac gataagaaaa taccatttcg
     2281 tcttttgtca aagttttcaa tgttccatct tcaagcaaaa gatccacttc agcaaaaaca
     2341 tctttgatct ctccgccata cgcacctgca ttcatataaa ccgctccacc gacacttccc
     2401 gggatgccgc aagcaaattc aaatccagtc aatgattctg ccaaagctgc ataagtcgta
     2461 tcaatcagtg aggcacctgc ttccgcaatg accatcgttc ctttgacatg aatctgtttc
     2521 atttcagtca gcatgatgac tacaccgcga atcccgccat cttgaacgat cagattgctt
     2581 gcatttccta ataccatcca aggtatatca tggattcggc aataatcgat gatttgcttt
     2641 acttcttctt gttttttcgg gaatgcaagg acatcagctg gtccacctgt tttcgtaaac
     2701 gtatagttca tcaatggttc atcaaacaat atagtaatcg tggctaagct ttcaactatt
     2761 tcttctttat tcactgagga ttttcctttc ttttctcaaa cgtcctcatt attctatcac
     2821 gcttaataca atcttgccag tcttgttcaa agttgatgac ggtagtgatc tttaagcact
     2881 tcctcacata attcatgact tcttacaact tctttttgtt taagcaattc tgtttccgat
     2941 ttacctaaac ggatctgaga aaagaaggcc tctaccattg gctcaaaccc gcgtttgact
     3001 agcgtgtttg tccagtcgcc aaattctttc actttttttc catcagcatc ttgaatgaca
     3061 agctgggtca gatcgtttac ttcataagta ccatttttac ttgttacttg atatttttct
     3121 atattagcgc cacttgctaa atccatcgtt aaaatagccg tttgattttg tgtttctaat
     3181 tgtaaaatgg catattccaa aaattccttt gtttctctta tctggtattt tgttctcaaa
     3241 atgggttcat ctaataaata cacagctgta tcaataagat gtaaaaacaa atcataaagg
     3301 acgaactctg tcgtttcttt tgccgctatt cgattttttt gcaggtggat caaccgctta
     3361 tctgggatac gtttcaattc ttctaccata ggagcaaagc gccggttgaa accgatcatc
     3421 aaaattattt ggttcttatc agctaattct tgcaattcac gaacttcatt tagatggaca
     3481 ctcagtggtt tgtcaatata aacatggata ccattttcta gacatttttt ggctaattca
     3541 taatgtactt ttgttgctgc gtggatcata catgcttcga ttttttcttc taaaagctca
     3601 tcgatcgttt catatagatg ttggaacccg tactcttttt gaattctttc ttttgtttct
     3661 ttatttcttg ttgcaaaata aaaatcaagt gttccttgtt ttttcgcata agttggtaaa
     3721 tatgcttttt ctgcgatatt ccctacaccg attacaccaa tcttcatcta ctttcctcct
     3781 ggatcattta gttactttca tcttacacca ttttttacta aaatgaggta caatagtatc
     3841 gcaaaggtaa ggaaattaat tcgaaggagt gtgcttttat tgaaatttat ctcttggaac
     3901 gtaaacgggc ttcgtgccat cgtaaataaa aattttttag aagtttttca tgagttagac
     3961 gccgattttt tctgtctgca ggaaacgaaa ctccaagcag gacaaattga tttagatctt
     4021 ccaggttatt atcaatattg gaattacgcg gaacgaaaag gctattccgg cacagcgatt
     4081 tttgctaaaa aaccagcatt gaatgccact tacggaatgg gtatcgatat ccatgataca
     4141 gaaggccgtc tgattacttt ggaatattcc gatttctttc ttgtaacctg ttacacgcca
     4201 aattctcaaa gcgaattaaa acgtttagat taccgattag aatgggaaga agccttttat
     4261 aattatttgg aaaatctaaa aaaacaaaaa ccagtcatcg tgtgtgggga tctaaatgtc
     4321 gctcatcaaa agattgattt gaaaaactgg aaaacgaatc aaaaaaatgc tggattcact
     4381 ccagaagaaa gagcggctct ttctcgactg ttggataacg ggtttatcga tacattccgt
     4441 tatttttacc caacccagga aggtgtctac tcttggtgga actaccgatt caattcaagg
     4501 aaaaacaatg ctggttggcg gatcgattac tttttgacga gcaaagattt agagccagga
     4561 ctagctgatg caaagatcca tacggacatt atgggcagtg atcattgtcc agtagaatta
     4621 gatttgaaat aaagaggttg tgaaaaagtc gtttagtttc gagtattaag aaaaattttg
     4681 tgaaaatggc tttccacatt ttgcataaat ttggcataat accgagaaac tggcttttga
     4741 acactgttta tcgagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa
     4801 acaaaaatag ttcctcatat ttttcgtttg gttgggctta ttaccgcaga tacaagcttt
     4861 tgaacaccgt ttattaagag gttgtgaaaa agctgcactg catcaagtaa taagaacagc
     4921 caaacaaaaa tagttcctca tatttttcgt ttggttgggc ttattaccgc agatgcaagc
     4981 ttttgaacac cgtttattaa gaggttgtga aaaagctgca ctgcatcaag taataagaac
     5041 agccaaacaa aaatagttcc tcatattttt cgtttggttg gacttattac cgcagatgca
     5101 agcttttgaa caccgtttat tgagaagttg tgaaatcagc gtcctgacct gagtattaga
     5161 gaaacaaatg gcaaaatagt tcctcatatt ttgctatttt ttgagctaat accgagggtc
     5221 agctgattga acactgttta gtggagaggt tgtgaaatca gcgtcctgac ctgagtatta
     5281 gagaaacaaa tggcaaaata gttcctcata ttttgctatt ttttgagcta ataccgaggg
     5341 tcagctgatt gaacaccgtt tagtggagaa gttgtgaaaa agtcgcctac tttcgagtcg
     5401 taagaaattt ttttgaaaat ggttcctcac aactttgcat aaatttgact taataccgag
     5461 aagtcatgat ccccatctaa ctccaaatca caaggaatga gttcaaaaac tagcttttct
     5521 caacaaatat tacataaaaa attctatgtt ttttgttaaa tttatttgct tttttcaaaa
     5581 gtatgttaca gtaatttccc aaggaggttt tacagaaatg aattttgttg ccatggattt
     5641 tgaaactgcc aatcatcagc cttatagtgc ttgttctctt gcgctagtca tggtaaaaaa
     5701 tagccagatc gttgatgaat tctatacatt gatacagcct gagactcctt ttttctggcg
     5761 aaatgtccaa attcacggaa tccatcaaga agacgtacgc aatgcgccga aattcccaga
     5821 agtctggcaa actatccaac catattttca aaaaaatcgt ttagtcgttg cacataatgc
     5881 tgcttttgat acaaaggtct tagcgggatg cttagattat tatcatcttg aacagcctaa
     5941 ttatctttct ttatgtacag tgaaaagtag ccgtcgcctg tttcctgaat ttccaaatca
     6001 tcgattgaac actgtgtgcg aaaatttgaa catccaatta gatcatcacc atgatgcatt
     6061 ggaagatagt cgtgcatgtg cggaaatcct gctttatcaa gaaaaaaaat tcgggacaga
     6121 tccattgaaa aaacttgtga ctataaagta aaagaatact tatgaaacac acaaagaggt
     6181 cgtgagcctg ccgtttcact ccgagtcaca aggagcaatt tcaaaaaata gcttctcatg
     6241 tttattaaat attgtgactg gtgaccgagg agctggcagg agaacaccgt ttattggaga
     6301 ggttgtgaaa aagctgttct gcatcaagta ataagaacag ccaaacaaaa atagcttctc
     6361 atatttttca tttggttgga cttattaccg cagatgcaag cttttggaca ccgtttacca
     6421 agaggttgtg aaatcagcgt tttgacctga gtattagaga aacaaacggc aaaatagttc
     6481 ctcatatttt gccgtttttt gagctaatac cgaaggtcag ctgattgaac accgtttatt
     6541 caaaaaaaat ggactgcgac acgacttttg tcacagtccc ttcgtgtgtt tttctgcctt
     6601 ctcaaaagga tgacagtttc tcactctttt cctatttctt ctattcaatc aaataactca
     6661 ttttatatac atctaaaaat tcacctagat ctgttcttgc ccctctaggc atgaccgctt
     6721 cgatttggaa gcccattttt cggtaaaggt gtacggctct ttcattacga acttgaacgt
     6781 caagctccaa tcgaaaaagt acacccattt ccttcgccca actgatgatt tcttctagca
     6841 taagagtgcc tagtcccatt ccccaatatt cctgcagaat actgataccg acttctccca
     6901 cgtgagacaa acgaaattga ctgtctgcct tgacagatgc tgttccaata atcgtccctt
     6961 catagattgc aagcagcaat aaattattat tgctttcgta tatataatcc aactcttctt
     7021 ctaaggtttc tggtggtaac aggagttctg cttcatccaa aactaaaaat tctgtctcct
     7081 tattaacttg tcccatcatc aaaagaatgt cttttgcatc tcctggcact gcttcccgca
     7141 agatgatccc aacttcttca ctcatgattt tcagcccatt tttctagaat tcgctgtttg
     7201 aaggtttcac tttgctcccc gtatgagatt agtttcacat accgcttttc taaatctgta
     7261 tcactttttt ctaaaatcag ttccaaataa tcctccggca gtgcttcttc taatagattt
     7321 ccccattcaa caacggaaag cccatcacct tcaaaatatt catctaaccc taaatctgct
     7381 ccgctagctg ctacccgata aatatccata tgatacaacg gaatccgacc ttgactatat
     7441 tctctaataa tcgtgtatgt cggacttttg atcatttgcg ttatccctaa tccttgggca
     7501 attcctttcg tcaacgttgt tttacccgca cctagatcac cagtcaatat cagattgtca
     7561 cctggcattg cggaatgacc aattgcctct gcgaattgtt ctgtcattgt taatcctgat
     7621 agttcgatca tttttcatct tctcccgctc ttctttcttt ttgccagtat atcgcgtaat
     7681 gaagtttttt taaagaaaaa atgaactagt caagaacagc agctgctgtt tttggctagt
     7741 tcgcgtgtat ttgttaatca atcaatgttt gtgctgctgt gataatcgat aatttatata
     7801 catcttcttc atttgctcca cgagacaaat cagaaaccgg tttgttcaag ccttgtagaa
     7861 ttggtccgat tgcttcaaag ttaccgaaac gctgagcaat tttatagccg atatttcctg
     7921 actgcaattc tggaaataca aagactgttg cttgaccagc tacttctgaa tctggcgctt
     7981 tcagttgtgc aactgaagga acataagaag catcaaattg caattcgccg tcgatcatgt
     8041 attgtggcgc tagtttttta gcgattttag ttgcttcaac tactttgtct acttctggcg
     8101 atttcgctga gccttttgtc gagaagctca tcattgctac ttttggttcg atatcgaaca
     8161 attctgctgt ttttgcagaa tctacggcga tttcagccaa ttcttgcgca gttggattca
     8221 cgttgatcgc acaatccgaa aagacatatt tttcttgatc tcttccacgt accatgatca
     8281 tcgctccgct tgtccgactg atgccaggct ttgttttgat gatctgaagt gctgggcgaa
     8341 cagtgtcgcc agtcgaatgg atcgctccag agaccattcc gtctgcaatc cccatatacg
     8401 taagcatcgt accaaagtaa ttcacatctt ttaaaatctt ttctgcttgt tctttggatg
     8461 cctttccatt tctacgttca acaaaagtat ccaccatttc atcccactta tcgtaattat
     8521 cagggctgat gatcgtaaag ctagatgttt tgattcctct ggcatgcgct gcatttctta
     8581 tttcttcttc gttccctact aaaatgggtt ccacaagttc ttctgctttc aaccgggcag
     8641 ctgcgcctaa aatacgagca tcagtagctt ccgggaaaac gattttgatc ccacggcgaa
     8701 caattttaaa tcttaaacta tcaaacaatt ccacaagatg acctccagac gtttttatat
     8761 gtattatcat acactattcc agaaaaaaag aacagtttat tttatctgta tcagtcaaaa
     8821 atgctggaaa aattaagttt ttcacataca aagcgaactg cactataaca ggaaagcgct
     8881 gttttattac actgtttcag gcagttgcca atcaatcggt tcttctccta acgcaaggag
     8941 cgcatcattc gttttcgaga agggtttgga accaaaaaag ccacgacttg cagataacgg
     9001 actgggatgt ggagatgtta tgatgatatg gcgactctta tcgatcattt tgattttttc
     9061 ttgtgccggt tttccccaca agataaacac gattggtttt tcccgttcat ttaatttttc
     9121 aatgatcgtg tctgttaatc tttcccaacc tttcccgcga tgagaatacg cttgcccttc
     9181 ccgaacggta agaacggtgt tgagtaaaag gactccctgt ttagcccatg acactagatt
     9241 tccatgttga acaggtgcga ttccaagatc atcataaagc tctttataga tatttcttaa
     9301 cgatggcggg atctttacgc caggttgcac agaaaaagat aagccatgag cttgattttc
     9361 tccatgataa ggatcttgtc ctaaaatcac cactttaact tcttcataag gagtcaattc
     9421 caatgcttca tagatatgat acatatctgg atggatcttt tgggacgcat attctttttt
     9481 taaaaattct cttagatgca gataataatc ttttgaaaat tctgaggaca aaacttcttg
     9541 ccaactgtta tgaatgattt ctttcaaaaa ctccacctcc taataaaaag aataactcac
     9601 attttcttca atcacaaggg acaatcttca ccctcagcac ttgattaata tggtaaacta
     9661 ggaacaagaa gcagaaagga acgataatca ttatgatcaa attaattgca tcagatatgg
     9721 acggcacatt attagatgcc catatgagtg tttctcctga aaatgccgag gcgatacgtt
     9781 ttgcaaatga tgccggtgtt gagttcatgg tcgctactgg tcgaaactat caagaagctc
     9841 gcgcagcttt agatgaggta ggaatcgatt gtgcgatgat cactttgaac ggggcacagg
     9901 tatttgataa agaaggaaat tcattgttta ccgtgtcgat tccaaataat caagcaatct
     9961 ctgttttaga tattctagat gctaacggta tttactatga agtagcaacc aacgatggtc
    10021 tttattctga aaatcaagcg aaacgaattg aaagttttgc ttccatggtg gctacccatt
    10081 tacctcacct tacgtataaa atggcgattg ccatggcctc agctaagctg gagttattgc
    10141 acatcacata cgtggacagt attcgtgcta ttttggaaga aaagaatctg gaagttttaa
    10201 aaattatttg ttttcataca gaagggccag ctgtattagg tccagttgga aagcagattt
    10261 ctcttttagg cgatctagcc gttacttcct ctggtcaaaa caatatcgaa gtgaaccata
    10321 aaaacgctca aaaaggaatt gctgttgccc atgtcgctca cgagcgtggg atttctttag
    10381 aagaagtcat gacgattggc gataacttca atgatgtcag catgctgcaa gtagcaggag
    10441 tcagtttcgc aatgggaaat gcagaaatcg aagtaaaaga ttatgccaaa tatacaacgg
    10501 acacaaacct tgaatctggc gtaggaaaag ccatattgcg cgcgattgca gaagacttgt
    10561 agttttatct agaaaagagg gatatagatg tcagaatttt tcattcagga aaagcagctt
    10621 ggacgtgcaa ctcggacaat tgtcaaaaac gaaaaaggac attccctgtt tttgatggtt
    10681 ggtcgctggg gaacaaaggg cgatgcattg tctctttatg ccatgaatgg cgatctcgtt
    10741 gctcacatca agcagataag cctgacattc ggtacgcgtt ttgagctgta taaagagttc
    10801 gaaaaggtgg gaaccatgca gaaaatattc aattggcccg gtgactttta ttatattcgt
    10861 agacttcact ggacagtcca aggtgatatc tataatcatc aatatcaaat ccatcatttc
    10921 aatcagcaaa tcatgaaaat ggataaagca acactttttt caggagatta ctatgtattg
    10981 gatgtctcaa atgatgaaga tgctccagtt tgtatttgta ttgctgcggt tttagattac
    11041 tggctctacc gtaaagacaa aagtcgcgat aagcctgttt cttaccgact taacttaagt
    11101 taaaaagatg tacctgaaat gcggaaatac gcatttcagg tacatctttt tagatattct
    11161 tttgcatatg atcataaaga tgaccactga tcatccgctg accgacaact ttgaagtcat
    11221 ggcgttcgta taatttttta gcctttggat ttttttcatc cacacttaga ccgatgacgg
    11281 agcgattagc tttcttcgcc aatttaggta atgcttctaa taatcgcgaa ccgatgcctt
    11341 gtcctctaaa atcttctgat acactgatag agtccaaata ccattcgttg ggaaacgttt
    11401 ctttatcaat gaacaaacgt gtagacgcat ctagctgata tttctctaag ataggtacca
    11461 gtggctgatc gatgattgat tcttcttcat ctgtataacc gtaagcaact cctgcaactt
    11521 taccgtctat ttcttctacg atacctcgtg aataactgta acgataattt ggatcagtga
    11581 ttgcttcttc taaaatctct aaagtctttt gttcccctgt ctgcttcaaa aatggcagtt
    11641 ccatatcttt tagaatcact aagatcaatg gggcgatttc tggagcatct tcttttctcg
    11701 caaaacgaat catagtttcc tctccttttc tccattctaa catgcagaaa aagaaatcgc
    11761 aaaatcgtta ttttaaaaaa tcttcaatct tttcagtaat gaaataacca tgagtaacga
    11821 ttcttgccgc ttcagttcgg caataagggc agacgactgg catttcttta tcattatgtt
    11881 cgactacatt attgacttct tcgtatgcaa atttttttcc gcaattaggg catttcattt
    11941 tttccatgtt atctcaactt cctttcatct ttactctctt agcttactct tatattgtaa
    12001 aaaagagaag caatatcctt cttctatgca gatatccata cctgacggtc ctgttctcca
    12061 tctattaatc ggactttata ataaggacgt tcatctttga ctagaagtgt ccactctttc
    12121 acttttgctt ttttcccgta gtagctgact gcttccttca tcgctgcttg cggttgtttg
    12181 aactcttccg ttttttctat atcaaaaaga tgttctgcgg ccttttccgt gtcatttcgt
    12241 acggttgttt tcccagtgga tggattgact gctatgactt gtccttcaca aaaaaactgg
    12301 tattcatatg ttgcattcgt aggattctcc aaatcttttt caactgcaaa atgaatagca
    12361 gatatgttat gttcttttgt ttcgtttttt acgattgctg ctgctttttt caatgagatc
    12421 cgatattcct ggtcactaat atcatccatg tgaaaagcgg cattgagcag tcccgtcata
    12481 ccggtaatcc ctattacgat gagggcagca acaccaaaca tcattttttt cattcttcat
    12541 tctcctgttt ctttttttta aagaatatca agaaatgaac gaatgaaaaa tcgaatgaaa
    12601 cgaaaaaaaa gtgacaattt tgttatcttt attcgtgcag ttctaatggc aatccgtctg
    12661 gatcaaagaa aaacgtcatt ttttttcctg taaaggtatc ttctctaatc ggttctgatt
    12721 cgatccctaa ggactgcaat tctgcaattg tttcttcaat atcgtctact ttgaaagcaa
    12781 gatgacgcaa gccacaagct tctggatagt ttggtcgttg tggcgcatta gcaattccaa
    12841 aaatctccaa ttcagcactt cctagtttca gatctaattt atagtcatct cgttctttgc
    12901 ggtaattttc tctgattact tcaaatccta atttattaac ataaaaatca cgtgatttct
    12961 gataatctga aacaatgatg gctatatgat ggatcgttgt aaggttcata tgagcactcc
    13021 tattcttcgt ttaagctcgg atctatatta atctccagtt ccattgtaaa tgtgtcagat
    13081 tgaaaaaaat agctgttttt cctttttata agaaaaaagg caaaaaaaac agaaagtagg
    13141 tcctccaaga cactcttcct gttcccaata taataaatga aagtaagaaa ttatattttc
    13201 aagaaaacaa acagaaaatt atcataacac aaattattta taattgaaag actagttttt
    13261 tttcaagaaa agcatacaat agattgtgtt agtaaataca gaacacacta catttagtgt
    13321 cttaaggagt cctcatacat gaagtcatat tttcagtttt tagctcatca gctaaaaggc
    13381 tggccgcaac aaaattatta tcttttcttt ttcagtcttg gctgccaggt catgactctt
    13441 gtcaatagtc ccatcacttg gctgtccgtt attacattta tcggtaccac gcttggtgta
    13501 ttgtgtattt tatccatcaa tgcggcaaaa tcagtcaacg gtattttagg tattttgtct
    13561 gcgatttgtt ttattatcgt tgggttttca gcaaagaact atttaagtat cggtgaacag
    13621 attgcttata tgatcacatt ggatatcccc gtattgttaa gtaaagaatg gaatcataat
    13681 atggcttcaa aaatccgaaa attcactgga aaaagctggt ttatcgcaat catcagtact
    13741 ttccttgtct atcttgtttc aggattcctg attggtcgtt atacagatga tcctcggccg
    13801 tgggtagatg ccattgcttt ttctattagc ttgactgctg gtatcatcag tttcttgcgt
    13861 tacaacaacc aatattactg gtggttagct tcagggcttg ctcaaatggt cctttggtat
    13921 atttcattta cgcatggatc tgcaagtttg gcgatgttcg tgaacagctc tgtttacttg
    13981 ctgaatgatg tccttgcatt taccgtttca ccttggtata accaaaaaga acgtgaacgt
    14041 atgcaaaaaa tggaagaaga atactacaac gcacaacaac acgcataaaa aaactgagcg
    14101 tgggacaaaa gtaaagaaca cttttgtctc acgctctaaa cacgtataaa cggcggaatc
    14161 agaagcaact ccttcggaaa taagctgaaa ttcacaaaaa tttgaaaagc aattttcgtg
    14221 aatttcttct tatttcttgg agttaaacgc ttctgtccca gcctctattt tttatagtaa
    14281 ttccttcaga tactttcttg cctcatcatt gaaacgcagt gattcttcta acttctgata
    14341 atattccaac gcttgtttct gagcttcagt aaaacgataa tgttttcctt tccatttgtc
    14401 gattgtctct tgcacatttc cagattggat atctttcact actagttgcc atttttcttt
    14461 tgagactgta cggtctttct tatcagcaga ttgtatagct tctcgttctt tacgcaatac
    14521 ttttaaaaaa ccatttctga ctatccgagg aatgctgtcg aagaaccctt ctgtaaaacc
    14581 atagcgacaa tattgcttcc aaataaatag atagattttt ggttggatga atcgttggtt
    14641 tttcgcaaaa tattccatct gagcagtgac ttctggtgtt cgttgacgtt ttgtctttct
    14701 caacacggaa ataaatgttt caaaataagc attaggatgt actggcactt cttcatatac
    14761 gatggattgc caatctttac gtaaaaatgc gcgatagttg atcaagaatt cttctacatc
    14821 ctttactaat tcttctgcaa agtcgtcaaa tagttctttt tttatctgtc gcttttttga
    14881 ctgcccattg atgtgttcac ttattttctt gatttcattt tccaatgctt gataatccgc
    14941 tatgtaaatc ggcatttcta cttggcgaaa ttctgcgagc cgctgagcta attttatatc
    15001 cggtaaatat ggctgtttca tccgacgatt ttggtacaag acaaaacagt atttttgcca
    15061 tagtccttca ggaaaatcga tattcttctg cttaagccat aataattcgt ctaaggccag
    15121 atcaactttt gtcattccct gatggatcga agctgccact gtcggagaga catgcaggtg
    15181 atcggcaaag tggttgatgc ctagttttag gatctttccg gtttttggcg atttaacgat
    15241 gtattgcact tttaattctc taccacactc acaatacaat ttttgctggc ttcgttttgt
    15301 tcgaaaaaac ggattgatct tgaagtcaga aaacacccaa tctgttgcag ctaaataatg
    15361 ttcttccata aaacgagagc tgattagata tcggcggtgc ttatcgacta gttcccgctg
    15421 ttttttcgtt aattttgcat agatctccca acgttgactg cttgtgtatt gtttagaaat
    15481 tttgatggga tagcttttgc tgatttcttt tggaaaccat tcttcaaaga cggattgcca
    15541 ttcttccacg gctgtttctt tcctttctaa ttacaaaaag ctggctacta acataacgtt
    15601 agcaaccagc cagtgtttct tgctaaatta gtgagttgtt ccggcatttc cggaaatatc
    15661 ttctttattt tctactgctg cttcaactgc ataagtcaaa gaagaagcaa tgtcttctaa
    15721 agacatagaa ggcgtaccca ctggacgatc gatcacttga tcgggtgaga atggcacgtg
    15781 gatgaaccca cctcgaattg ccgggaattg tgtttcgatc aaatgaagca aacgatacat
    15841 gatatcattg cagacaaatg ttcctgctgt ataagagatg tacgctggta gaccatgatc
    15901 ttgtacattt tttgtcattg ctttgattgg caatgaggta aagtaagcgg ctggaccgtt
    15961 ttcttctaaa gccgtatcga atggctgatt tccttcatta tcagggattc ttgcttctgc
    16021 tagattgatt gcgacacgtt cgaacgagac tgctgaccgc ccacctgctt gtccgacaca
    16081 gatcacgaca tctggttggt gctgttggat ggcttctttg actacttgac tgcttttttc
    16141 gaatacggtc ggtacttcca ctttgatgat ttcagcaccg ctgatttcat ctggcatttt
    16201 ttttactgct tcataggctg gattcacttt gtccccacca aatggatcaa aacctgttac
    16261 tagtactttc atctgttgtt cctccgtccg attgatttaa catatggtta tcttttatca
    16321 taccattttc cttgaacagc gtaaataaag gaaacaatag tttaaataac ataacagatc
    16381 aaacttaata tattcttata aaaaaatagt gttccactac aatgttagaa gaggttgcga
    16441 caattattct gtcacaaccc ctctcttcta ttatttaaat agaatcatat aagcaatttg
    16501 gaaaactagc ataaataacg caataaacaa ctggtttttg atcactccgt atttgtcttt
    16561 catctccagc atcgctacag gcacgatatt gaagttagca gccatcggtg tcagcagggt
    16621 cccacaaaaa ccgcaagtca atgcaaccat tcctattaac gctggattcg ctccatgact
    16681 aaatacgaat ggtgcaccga tcccaaccgt catcacggtg atggccgcaa atgcattccc
    16741 catgattacc gtaaatatca ccatgccaag agcgtaaatg atgatgccga tgttcacatt
    16801 tccttctgga acgatcgtac ctactgcatt ggaaatcact gtcccaactc cagcgcttgt
    16861 aaataccgca cctagagaag ctaaaagcat tggcaacatg cttaacggcc ctactgtgcc
    16921 cagcatatct gctgcatcat ctaaaaatgt acttggtcga ttatctcgag aaaagaacat
    16981 caagattagc atggctgcaa aaacaccgac gcccacgccg actaaagcac ctaaattggt
    17041 aaatagagca aacaagatcg caaagacacc gatactcaaa gctggaataa aaattttcat
    17101 tcctagtttg tctgacattt tttccatata ttcttttgat ggaagccggc tttctccttt
    17161 gctgactttc ttagcaattg ctggtatggt catcgcaaag atcaagccac cgttcacgat
    17221 tgccggaagc catcttcctc ctgcaataac tacccctaag accgtccaga aaaaggctga
    17281 cccataacga tgaggattgg ttttatctgt taaatttctt actccagtgt aaatcaatac
    17341 gagtcccatc acgatataaa ggatctccag taatttatcg cctaataaaa tatcaggatt
    17401 tgtaaaaaag tccatcttat tgcccctttc ctggataata tttcttcgct aatttctttt
    17461 ctttaagata gaagtagaca cttgccacaa ctaaagccgt gatagccact ggaacttcca
    17521 ctaaagcaag ctgtcccaat gttacgtcat atcctagatc tttcagtgtt gattggacta
    17581 gcaacgcccc tgctcctccg atgaatagta cttggccaaa gaaccagcag acattttcca
    17641 tagctgaagc catacctttt agttcttctt catgcttagg atggacttct aacccttttg
    17701 attcgatggt ccccaatgcc atcggtaaaa tgattggacg aacaaatcca gcaactccac
    17761 caaaactcac gttaaaagcc gcaaagatca ttcgaaagat cccataaata tctacaatca
    17821 taccagcaga tactttcttg aatcgcttga tcaaggaagc cgctgattct ttcagaccat
    17881 ttctttcaag cgttcctgtt gccaacataa tgatgataaa aatcgccatc ccgcgattgt
    17941 ttacaaaact tgtacctaaa agttctaaca ttccttgaat gccaagaccg ccagtcaaag
    18001 ctgtaacaac taaagcaacc attacgatca atatcgagtc taatttaaat gcaaacccga
    18061 gaataacaat caagacgcct aaaaggctaa gataattttc catata
//
LOCUS       DACDAF010000056        17811 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.056, whole genome shotgun sequence.
ACCESSION   DACDAF010000056 DACDAF010000000
VERSION     DACDAF010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17811
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.056"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            100..912
                     /locus_tag="IVZ69_001804"
     CDS             100..912
                     /locus_tag="IVZ69_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HAP8183883.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            909..1709
                     /locus_tag="IVZ69_001805"
     CDS             909..1709
                     /locus_tag="IVZ69_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HAP8183884.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1870..3138
                     /gene="rseP"
                     /locus_tag="IVZ69_001806"
     CDS             1870..3138
                     /gene="rseP"
                     /locus_tag="IVZ69_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HAP8183885.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3206..4915
                     /locus_tag="IVZ69_001807"
     CDS             3206..4915
                     /locus_tag="IVZ69_001807"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HAP8183886.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5127..9479
                     /locus_tag="IVZ69_001808"
     CDS             5127..9479
                     /locus_tag="IVZ69_001808"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HAP8183887.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            9623..10096
                     /gene="rimP"
                     /locus_tag="IVZ69_001809"
     CDS             9623..10096
                     /gene="rimP"
                     /locus_tag="IVZ69_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HAP8183888.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10120..11295
                     /gene="nusA"
                     /locus_tag="IVZ69_001810"
     CDS             10120..11295
                     /gene="nusA"
                     /locus_tag="IVZ69_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HAP8183889.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11317..11610
                     /locus_tag="IVZ69_001811"
     CDS             11317..11610
                     /locus_tag="IVZ69_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HAP8183890.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11607..11918
                     /locus_tag="IVZ69_001812"
     CDS             11607..11918
                     /locus_tag="IVZ69_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HAP8183891.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11931..14237
                     /gene="infB"
                     /locus_tag="IVZ69_001813"
     CDS             11931..14237
                     /gene="infB"
                     /locus_tag="IVZ69_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HAP8183892.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14264..14611
                     /gene="rbfA"
                     /locus_tag="IVZ69_001814"
     CDS             14264..14611
                     /gene="rbfA"
                     /locus_tag="IVZ69_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HAP8183893.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(14719..14940)
                     /locus_tag="IVZ69_001815"
     CDS             complement(14719..14940)
                     /locus_tag="IVZ69_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8183894.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            15388..17751
                     /locus_tag="IVZ69_001816"
     CDS             15388..17751
                     /locus_tag="IVZ69_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HAP8183895.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
BASE COUNT         6080 a         3153 c         3919 g         4659 t
ORIGIN      
        1 gtttttaaat aaaaaaacaa tgatttcata ggaaaaacag ttagatattg ctataatact
       61 taagatagtg ggaatctttt aagtatagga ggaaaaagaa tgttacgttt ttttccgcaa
      121 aaaaacaaat atattcaaga aaaaagcgaa tttcaattta ataccgatgg accaattcct
      181 cagcacattg ccatcatcat ggacggcaat ggtcgttggg cgcaaaaccg tcgtttgcca
      241 cgagttgctg gccataaaga aggcatggaa acagtaaaga aagtcacaaa aaaagcatca
      301 aggcttggag tgaaagtgtt gacgctttat gccttttcga ctgaaaactg gaagcgacca
      361 aaagatgaag taagttttct catgcaacta cctgtcgact tctttgatac gttcgtacca
      421 gaattgatta aagaaaatgt caaagttcat gtcatgggtt atgaaaacgt attgccagaa
      481 catacgcaag atgctgtaag acgtgcaatt gagcaaacaa aaaacaatac tggaatggta
      541 ttgaattttg ctttgaatta tggaagtaga gcagagatcg tgactgctgt ccaagaaatt
      601 gccgaagaag tagcaaaagg agaaatacac gcagaagaaa tcgatgatga attgattgct
      661 aagcatttaa tgacaggttt cttgcctaaa gagttacaag atcctgagct gatgatccgt
      721 acaagtggag aagagcgaat tagtaatttt ctgttatggc agatcgcata tagtgagctg
      781 tattttacaa aagcgctttg gcctgatttt gatggtgcgc atcttgaaga agcaatcgcc
      841 tcttatcaaa atcgagaccg tcgattcggc ggtgtaaaaa aaacagaaga tgagaaaggg
      901 gatcagtcat gaaacaacgt gtgatcacag cagctgtggc gctagtcttg tttattccga
      961 ttatatggat cggaggcata gcggttgagc ttacagcagc aatcttagcg gtagtaggag
     1021 tttacgagct gttccggatg aaaggattga cactcttaag ttttgaagga gttttatccg
     1081 ccgttggtgc agtgttactt gttttgccaa aagaaagatg gtttttcttt cttccagaga
     1141 atgtaagtac atttatgtta ttttatctta tagttatgat tcttttagga acatcagtta
     1201 tttctaaaaa tacgtatacg attgatgaag caggttttcc tgtgcttgtc agcttgtatg
     1261 tgggaatagg tttccagaat tttgtcaatg cacgaacaga aagcttggct gttttgatat
     1321 ttggtctatt tattgtttgg gcaactgata tcggagcata tatggttggt cgacgttatg
     1381 gtcagcataa gttaagtcct gatatttcgc ccaacaaaac gattgaaggt gcgctcggtg
     1441 gtatcggtag tgctgttgta gtcgcatttc tttatttatt gctataccca gcaaaagaac
     1501 tattcaatca tggtatgttt gtcatgcttc tgatgacgat tattttttca gcagtcggac
     1561 aatttggtga tttggtcgaa tctgcaatca aacgtcatta tgatgtgaaa gactcgggaa
     1621 atatcttacc aggccatggt ggaatcttag accgtttcga cagtttgctg tttgtatttc
     1681 ctatcatgca tttatttggc attatttagt aagtatacct gcgtttcttt gtgaatttca
     1741 taaaagacgc aggtttttat ttttcattat attgatacta ttggtgtctt tggtatacta
     1801 tggtaaaatt atagtgtttt atcgttgttt tataaaaaac acaaaaaaca agtaaaggag
     1861 aaaaaagcta tgaaaacgat tctgacattt atcatcgttt ttggtatatt agtgattgtt
     1921 catgagtttg gtcatttctt ctttgcgaaa cgatcaggaa tcctcgtccg cgaatttgct
     1981 atcggtatgg gtccgaaaat ttatgggcat caagcaaaag acgggacaac atatacgctt
     2041 cgcctattac ctattggcgg ttatgttcga atggcaggca atggggatga tgaaacagaa
     2101 atggcaccag gaatgcctct ttctctttta ctaaattctg acggcatcgt agagaagata
     2161 aatttaagta agaaaatcca attgacaaat gctatcccga tggaattgag ccgttatgat
     2221 ttagaagatg agctgactat cactggttat gtgaatggag acgaaacaga agtagtaacc
     2281 taccctgttg atcacgatgc gacgattatt gaaaacgacg gaacagaaat cagaattgcg
     2341 ccaaaagacg tacagttcca atcggctaaa ttgtggcagc gtatgctgac caactttgct
     2401 ggacccatga ataactttat tttggcaatc gtgttattca tcattctggc atttatgcaa
     2461 ggtggtgttc aagtgacgaa cactaatcgc gtaggagaga tcatgcctaa tggagctgcg
     2521 gcagaagcag gcttaaaaga aaatgatgag gtagtcagtg tggacggaaa agaaatccat
     2581 tcatggaatg atctgacaac agtcattacg aaaaatccag gtaaaacatt agactttaag
     2641 atcgaacgag aaggtcaggt gcaatctgtc gacgtgacac cgaaatctgt agagtcaaat
     2701 ggcgaaaaag ttggccaact tggtataaaa gccccaatga atacaggttt tatggataag
     2761 atcattggag ggacgcgtca agctttcagc ggttcattgg aaattttcaa agccttagga
     2821 tcactattta caggtttcag tttagataaa ttaggcggac ctgtcatgat gtaccaattg
     2881 tcttcagaag cagcaaatca aggtgtaaca actgttatta gtttgatggc gcttctttca
     2941 atgaatctcg gaatcgtcaa tctgcttccg attcctgcct tagatggcgg gaaattagtc
     3001 ttgaatattt ttgaagggat tcgcgggaaa ccattaagtc aagaaaaaga aggaatattg
     3061 acattagctg gctttggatt tttaatgttg ttgatggtgc tagttacatg gaacgatatt
     3121 caacgattct ttttctagaa aaagttgaca aatagggtat aataacaaac gataactatt
     3181 ttgaggaaat aaaggagtat atagaatgag acaatcaaaa atgttgattc caacattacg
     3241 cgaagttcca aatgatgcag aagtattaag ccatcaaatc ttgctaagag ctggatatat
     3301 ccgccaagta tcagcgggta tttattcata tctgccatta gcaaatcgtg tattggaaaa
     3361 actgaaacgc attatgcggg aagaatttga aaaaatcgga gcggtagaaa tgctgatgcc
     3421 tgccatcttg ccagcagaac tttgggaaga atccgggcgt tacgaaacat atggaccaaa
     3481 cttgtatcgt ttcaaagacc gcaatgatcg aaaaatgatc cttggaccaa ctcacgaaga
     3541 aacttttact gatttgatgc gtaatgaaat caattcatat aagaaattac ctttaaatct
     3601 ttatcaaatc caacctaaat atcgtgacga aaaacgacct cgcttcggtt tgcttcgcgg
     3661 aagagagttt atcatgaaag atgcatattc tttccatgca acggaagaaa gtttggacga
     3721 gacatataaa gattacgaaa aagcctatac cgaagtattc aagcgttgtg gcttagaatt
     3781 tcgctcgatc atcggagacg gcggcgcaat gggcgggaaa gactcaaagg aattcatggc
     3841 gatctcagaa atcggggagg atacgatctg ttattcgact gaaagtgatt atgctgcaaa
     3901 cttggagatg gctacaagct actatgtatc aaaaaaatcg catgaaacac agcttgaatt
     3961 ggagaaagta gctacaccta acgtaaaatc aattgacgaa gtagcagatt tcttttctgt
     4021 tgaacctcaa aaaatcatca agtctgtatt gttcattgcg gatgaacaac ctgtccttgt
     4081 tttggtacgt ggagaccatg aagtcaatga cgtaaaactg aaaaactttt tatctgctga
     4141 ctttttagaa gaagcaacag aagaagaagc acaaaaatat ctaggtgctg agtttggttc
     4201 tgtcggacca gtcggtgttt cagatgacgt aaaagtatat gcagaccgtt atgtccaaga
     4261 tttagcgaat gccattactg gagcgaacga aacaggattc cactataaaa atgtgaatcc
     4321 aaaacgcgat ttcactgtgc tttcttatga agatcttcgt tttgtacaag aaggagatcc
     4381 ttcaccagac aacaacggtg ttcttgcctt tactcgagga atcgaaatcg gacatatatt
     4441 caaaatcggc actcgttaca gtgaatctat gggagcaact gtactagacg aaaatggacg
     4501 agaaaaattt gtgattatgg gctgttatgg tatcggtgta agtcgtttat tatcagcaat
     4561 cgtagaacaa cattcagatg aacaaggaat caattggcca aaaggaattg cgccatttga
     4621 tctgcatatc gtccaaatga atctaaaaga cgaataccaa acaagcctga cgaatgaact
     4681 agaagaagcg atgacaaaag ctggctatga agtactggtt gatgacagaa atgaacgcgc
     4741 aggagtgaaa ttcgcggatt ctgatttgat tggctgtcca atcagaatca ctgtcggtaa
     4801 aaaagcagtg gatggaatcg tagaagtgaa aatcaagaaa actggcgaaa tggttgaagt
     4861 acgtaaagaa gaattggcga atactttacc aatcctcttg aaccaaggcg aataataagc
     4921 gttaaaacac agaaaataaa aatagctgaa tcagctgttt ttgacaatct gatgattcgc
     4981 ttttaaaatt ggaactgcga tttgaatcgc agttccaatt ttttaatgta aaactcagaa
     5041 aaaacgagta tactaaaagg tactgaaaaa gaagaggata agatgcgatc aattgcattg
     5101 tttctcatca gaaagggcgt atatctttgt cagaaaaacg agatttattt gaaaaactgt
     5161 tggaacaaat ccaactagag gaagcagaaa aaaatcatcc actgcttact gctggtgaaa
     5221 tggatagtgt agtggtccat cgtaaatcgc gtttatggga atttacgcta catttttcca
     5281 aaattttgcc tattatgcta tatcggtcat tgactcagca tctgactatc gcttttaaag
     5341 atattgcaca agtcaaactg aatatcttag cagatgacca gacattcgat gaacagctct
     5401 tgcaagatta ctgggcccaa gctttggaaa atcagcaatg cgatacacca ctagcacagc
     5461 aagtattgaa aacgcaggta cctgtgataa aagatcgtaa agtcatcttg ccaatcgaca
     5521 gtacaggagc tatttcttat ttgaagcaac aatacttgcc attagtagaa gagttgttcg
     5581 tcagttacgg attcccaaaa tttcgtatcg aaccagaagt ggatgagcag caagcggaac
     5641 gtgtattgaa actttttgaa gaacgcaaac aagaacaggc agaagccttt atgaagcaag
     5701 cagctgaaag tctagttgtc cacgaacaaa agaaaaagga aagaaaagag caatcgccag
     5761 ctcttgaagg acccatccag ctaggacgaa atattccagc cgatgaacca acgacaccaa
     5821 tgatcagtat cgttgaagaa gaacgaagag tcacacttga ggggtacgta ttcgacaaag
     5881 aagtcagaga actacgttca aaacgcaaga tcttgacttt gaaaatcaca gattatactt
     5941 catcatttat cgtcaaaaaa ttctcgaacg gcgaaaaaga tgaacaagta tttgatgcga
     6001 tcagtgtcgg tagctggtta aaggtacgag gaagtattca agaagatacg tttgtccgtg
     6061 atttggtcat gaatgcgcaa gatatcatag aagtcaaaca tacacctcgc aaagattatg
     6121 ctcctgaagg ggaaaaacga gtagagcttc atgttcatag caatatgagt acgatggatg
     6181 caacaaacag catctctgat cttgtggcac aagcaggaaa atggggacac cgagctatcg
     6241 ccattacaga ccatggtggt gcgcaagcct ttccggaagc acatagtgct ggaaaaaaag
     6301 caggtgtgaa aatcttatac ggcgtggaag cgaatgtcgt agatgatggt gtcccaattg
     6361 cttataatga tgcacatgaa gcattgagtg aagccacata cgtcgtattt gacgtggaaa
     6421 cgacaggatt gtctgcagta tatgacacga tcatcgagct agccgcagtc aaaatgtata
     6481 aaggaaatgt gatcgaaagc tttgatgaat ttatcgatcc aggacatcca ttgtcacgaa
     6541 caacggtaga tctgactggt atcacggatg aaatggttcg agggtcaaag tcggaagaag
     6601 aagtattgcg gatgttcctt gaattttcaa aagatacaat tttggtagcc cacaacgcgg
     6661 cttttgatat ggggttcttg aatactagct acgcaaggta tggtattcct gaagcggcca
     6721 atccagtcat tgatacgttg gaattagcta gatatctgta tcctcaattc aaacgtttcg
     6781 gattaggtgt gttatctaaa aagtttggtg ttagcttgga acagcatcac cgagcaatct
     6841 atgatgctga agcaactggt cacttagcat ggatctttgt gaaagaggca atggacaatc
     6901 ataacatgct ttatcatgat cagctaaatg agcatatcgg agaaggagat tcttacaaaa
     6961 gggctcgacc tttccatgta acgattttag caaaaaatca ggcaggactg aaagatttgt
     7021 tcaaactgat ttcaatgtcg aatgtcgaat acttcgaacg cgtcccacga ataccacgct
     7081 cccaattgaa aaagatgcgt gaaaatctat tgatcggctc agcttgtgat aagggagaaa
     7141 tattcgaagc catgatgcaa aaaggggtag aagaggcaag aaaccgagca aaattctatg
     7201 attatattga agttatgcca aaagcggtct atgcgccttt gatcgagcaa gaattggtaa
     7261 aaaatgaaca tgatttggaa gaaattatcc aaaatttggt agaaatcgga aaaagtttgg
     7321 ataaaatcgt tgttgcaaca ggtaatgtac attatctgaa cgaagaagat gccatttacc
     7381 gaaaaatttt gatcaattct atgggcggag cgaatccgtt gaatcgtcat agtttgccgg
     7441 atgtccattt ccgaacaacc gatgagatgc taactgcatt tcacttttta ggggaagaaa
     7501 cagcgaaaga gatcgtagta gaaaatacga ataaaatcgc agatatctgc gaagaagtga
     7561 ttccagtcaa agatgaactt tatacaccga agattccagg ttcagaagat gaaatatcag
     7621 aattgagtta cacaaaagca aaacaaatgt acggagatcc gttacctgag atcattcaaa
     7681 aacgattaga aaaagagttg aattctatta atggtaatgg cttctcggtt atttatctga
     7741 tcgcccaaaa actagtgcat aaaagtaatg aagatggcta tctagtaggt tcacgtggct
     7801 ctgttggctc tagctttgtt gcgacgatga caggaatcac tgaagttaat ccattagccc
     7861 ctcattatta ttgtccagag tgccaatatt ccgagttttt tgaagatggt acgtatggtt
     7921 ctggatttga catgccagaa aaacaatgtc caaaatgtgg tgcacgctta aacaaagacg
     7981 gtcatgatat tccatttgag acatttttag gattccatgg agacaaagtg cccgatattg
     8041 atttgaactt ctcaggtgat tatcaagcag aagcccataa ctatacgaaa gtattgtttg
     8101 gcgaagacta tgtttaccgt gccggaacga ttggtacagt cgccgacaaa acagcatatg
     8161 gctatgtaaa aggatacgaa agggacaata atctgcagtt tcgaagtgca gaagtcgaca
     8221 gattagcaaa aggcgctact ggagtcaaac ggacaaccgg ccagcatcca ggggggatca
     8281 tcgttattcc cgattatatg gatgtctatg attttacgcc gatccaatat ccagcagacg
     8341 atcaaaattc agaatggaaa acgactcatt ttgatttcca ctcgattcac gataatgtat
     8401 tgaaattaga tattctaggg catgatgacc caactgttat tcggatgctt caagatttat
     8461 cagggatcga cccacaaacg atccctacgg atgacccgga agtgatgcgg atatttgccg
     8521 gtcctgaagt acttggagta agtcaggaac aaatttattc caaaacaggg acattaggta
     8581 ttccagaatt cggcactcgt tttgttcgag ggatgttaga agaaacgcat cctacaactt
     8641 ttgcagaact actgcaaatt tccggactat ctcatggtac agacgtatgg ttaggaaatg
     8701 cggaagaatt gattcgacga ggagatgcga cactggcgga agtaatcggc tgtcgtgatg
     8761 atattatggt ttatttgatc catgctggat tagatagcgg gatggcattt aaaatcatgg
     8821 aaactgttcg taaaggacaa tggaacaaga tccctgatga attgcgagaa acctatctat
     8881 cggcgatgaa agaaaataat gtgcccgact ggtatatcga ttcttgttca aaaatcaaat
     8941 atatgtttcc gaaagcccat gctgcagctt acgtattgat ggctcttcgt gtcgcttatt
     9001 tcaaggttta tttccctatt ttgtattact gtgcatactt ttctgtacgt gcagacgact
     9061 ttgatctagt ctccatgtgc aaaggaaaag atgctgtgaa acaagcaatg aaagaaatca
     9121 cggacaaggg attagatgct tccgtaaaag aaaagaatca actgacagtg ctggagttag
     9181 ccaatgaaat gctggaacga ggattcaaat ttggaatgat tgatttgtat aaatcggatg
     9241 ccgttaactt tgttattgaa ggtgatacgt tgatcgcacc atttagagct gtcccaagtt
     9301 tgggaaccaa cgtggcgaaa caaatcgttg aagcaagaaa agacggtcca tttttatcca
     9361 aagaagatct tgccacccgc ggtaaagttt caaaaacatt gatcgaatat atgaacgaca
     9421 atggcgtatt gaaagatcta ccagatgaaa atcaattatc gttattcgat atgctataag
     9481 catctgtttt cctgtctgct tgtaatttta agcagagtat ggtatagttc ttataggtaa
     9541 tgatactaac tgtgagtgag cggatttttc gctcactctt tttaatggaa ttacgcactt
     9601 aatttttaag gaggcgaaac ttttgagtag cgtcgttgaa acagtcacag aaatggtgac
     9661 accgatttta gatgaacaaa attttgaact tgtcgaagtc gaatttgtaa aagaaggaaa
     9721 aagctggttc ttacgagtat ttattgacaa agaaggcggt atcgatatcg aagaatgcgc
     9781 ctttgtcagt gagaaactga gtgaaaaact tgatgcagca gatccagatc cgattcctca
     9841 agcttatttc ctggaggtat cctccccggg agcagagcgg ccattgaaaa aagaaagcga
     9901 ctatgaaaag gcacttggtg attatgtcca tgtctcctta taccaaccag tagatggcga
     9961 aaaacaatat gaaggatttc ttcaatcatt tgatgctgaa cagcttacat tgaaaatacg
    10021 cataaaaaca cgagaaaaag aattgacttt tgaccgaaaa aatattgcaa aagctcgctt
    10081 agctatccaa ttttaatcac ggagaggaat cagaaaaaaa tgagtaaaga aatgttaaat
    10141 gcgttagacg ctttagaagc tgaaaaaggg atctcaaaag aaatcgtgat cgatgcttta
    10201 gaagcagcat tggtttctgc atacaaacgt cactatggcc aagcacaaaa cgtcgaagtg
    10261 gaatttgatc agaaaaaagg aaagatccat gtctatgcgg taaaagaagt aacggaagaa
    10321 gtgatggatt cacagttgga agtctcattg aaagatgcac ttttaatcaa tccagcatat
    10381 gagatcggtg atacgatccg ttttgaagta acaccaaaag attttggacg gatcgctgcg
    10441 caaacggcta aacaagttat tttacagcgt gtacgtgaag cagaaagaac gattatttat
    10501 aacgaattca gtgcttatga aaaagacatc atgcaaggaa tcgtcgaacg ccaggataaa
    10561 cgttatattt atgtcaatct tggtaaaatt gaggcagttc tttctaaaca agatcaaatg
    10621 ccaaatgaat tttatcaacc acatgatcga atcaaagttt atgtttcccg agtagaaaat
    10681 acgtctaaag gtccgcaagt atttgttagc cgcagccatc cagacctatt gcgtcgctta
    10741 tttgaacaag aagtaccaga agtctatgat ggaatcgttg aaattgtcag catcgcccgt
    10801 gaagctggcg atcgttcaaa agtggcagtt cgctcaaatg atccaaatat cgatgcagtc
    10861 ggtacatgtg tcgggccaaa gggacaacga gttcaagcaa tcgtcaatga attaaaaggc
    10921 gaaaacatgg atatcgtcga atggaatgaa gatccagctg tattcatcgc aaatgcattg
    10981 aatcctgcac aagtcatgga tgtgatcttc gatgagacaa atccaaaggc ctgcacagtt
    11041 gtcgttccag actaccaatt atcgctagca atcggtaaac gcggacaaaa tgcacgttta
    11101 gctgctaaat tgactaacca taaaatcgat atcaaatcag aatctgacat gacggaattt
    11161 tatgaaaatc aagaacaaca aaaagaaaca gaagaactgc atgatgaagc aatcgttcag
    11221 tcagatttaa cagacgatga atatgaaaca attgcattca acaatgaaac ggtcgaagaa
    11281 aaaccagaag cttaacttta gtaaggaggc aaagagatga aacaaaggaa aattccttta
    11341 cgcaaatccg tggtttcagg tgaaatgaaa cctaaaaaag agatggtccg aatcacccgt
    11401 tcaaaagaag gggaagtatc gatcgatcca actggaaaaa tgcctggacg aggagcgtat
    11461 gtctcacttg agccggaaga agtacaacaa gcttgggata aaaaaattct cgatcgagta
    11521 ctcgaaacaa cattaacaga tgagttttat caagaacttc ttgactatgt cactcaccaa
    11581 aaagcacgta aagagttatt tggaaaatga atacagttaa tcggcaaaaa gccatgaatc
    11641 tcatcggtct agcgatgcgc gcgggaaaac taatcacggg tgaagaactg accattgctg
    11701 aaatccgcaa acaaaaagca aaattggtgt ttgtggcaac cgatgcaagt gagaatacaa
    11761 gaaaaaagat aaaagataag agttcatatt atgaagttcc ttgctttgag ctattttctg
    11821 aagcagaaat cacgcagatg atcggaaaac ctcgcaaggt attcggaata atggatgccg
    11881 gatttgcgaa gaagaccaag gagctaattg aaggttagga aggtgattgc atgggcaaca
    11941 aaagaatcta tgaattagca aaagaactca aaaaatctag taaagacgtc gtggaaaaag
    12001 cacaacaact tggcatcgat gtgaaaaacc atatgggtgc gattactagc agtgatgaga
    12061 agaaattgca acaagcgttc aaaaacccaa gcacgaaaca acaagctgca caacaagcaa
    12121 gcagaaaacc agccaatcaa cagccgaacg atcaacgtaa aaaagaaaca acgaacaatc
    12181 aacaaaaaaa taaaaataac cgcagttatc aagatcgcgg tcaagggagc ggtcaagtga
    12241 atcaaggaaa aaaaccaaca acaaaccaaa ataatacggg aaataccagc agccaaaatc
    12301 gtcaaggaac gagccaaggc ggcaatcaaa accgtactaa caataacaac aaaccaaaca
    12361 ataacaatcg cggcaaattt aataataata accgtaatcg ttataataaa aaaggtaaaa
    12421 aaggcaaaca gcaacaatca actaaaccag ctgtaccacc acgcaaattc cgtgaattgc
    12481 cagatgtatt agagtatact gaaggtatga acgtagcaga tattgcgaaa aaaattcatc
    12541 gtgagccagc agaaatcatt aaaaaattat ttatgcttgg tgtcatggtc aatcaaaacc
    12601 aagcactgga taaagatacg attgaactgt tagcgacgga ctatggcatg gaaccacaag
    12661 aaaaagtcca agttgacatt gctgatatcg ataaattctt cgaggcagaa gaagtcgatc
    12721 cagataaatt agtctcacgt ccgccagtag taacgattat gggacacgta gaccacggga
    12781 aaacaacctt attggataca ttgcgccatt cacgtgtaac aagcggcgaa gccggcggaa
    12841 tcacacagca tatcggtgcc taccagatcg atattgatgg taaaccaatc actttcttgg
    12901 atacaccagg acatgcggcc tttacaagta tgcgtgcacg tggagcaagt atcacagata
    12961 tcacgatctt agttgttgct gcagatgatg gcgtcatgcc acaaacagtt gaagcaatca
    13021 accatgccaa agctgcaggc gttccaatca tcgtcgctgt aaataaaatt gataaaccag
    13081 gtgcaaatcc tcagcatgtt atgcaagaat taagtgagta tgaattaatt cctgaagcat
    13141 ggggtggaga aacgattttt gttgagatct cagcgaaatt cggccaaaac atcgaagaat
    13201 tgctggaaat gatcctgtta gtcgcagaag tagaagattt aaaagcagat ccaacacaac
    13261 gcgcaatcgg aacagtgatc gaagcacgtc ttgataaagg taaaggtcct gtgtcaacct
    13321 tacttgtcca agaaggaaca cttcacgttg gtgacccaat cgttgtcggt aatacttacg
    13381 gacgtgtccg tgtaatgaca aacgatcttg gccgtcgcga taaagaagca ggacctgcaa
    13441 cgccagtaga aatcactggc ttgaatgatg tacctcaagc aggtgaccgt ttcgtagtct
    13501 tcgaagacga aaagacagca cgtgcagcgg gtgaagaacg cgcaaaacgt gcattattgg
    13561 aaaaccgtgc tgccacaagc cgtgtgactt tggacaactt atttgaaagc ctgaaagaag
    13621 gcgaattgaa agaagttaac gtaatcatca aagcagatgt acaaggttca gcagaagcac
    13681 tggctgcatc attgaagaag attgatgtgg aaggtgtccg tgtaaaaatc gtccattcag
    13741 ctgtcggagc aatcaatgaa agtgatgtaa ccttagcagc agccagcaac gctattatca
    13801 tcggtttcaa cgttcgtcct acaccgcagg caaaagtgca agctgatact gaagaagtcg
    13861 atattcgtct tcaccgtatc atctataaag ccatcgaaga aatcgaaact gcgatgaaag
    13921 ggatgctaga ccctgaattt gaagaaaaaa tcaccggtca aatgatcgtt cgtgaaacct
    13981 tcaaagtttc taaagttggt acgattgcag gtgcctatgt aacagaagga tatattcgta
    14041 gagatagcgg tgtccgtgta atccgtgacg gaatcgtaat ctatgaaggc caacttgcaa
    14101 gtctgaaacg attcaaagat gacgtgaaag aagtcaaaat gggttatgaa tgtggtgcga
    14161 tgattgaaaa attcaatgac atcaaagtag atgacgtaat tgaaggattt atcatggaag
    14221 aagtcaaaaa tgactaaaaa ctgataaaag gaggccaatc attatggcta actaccgtga
    14281 tcgccgagtc ggtcaagaaa tcttaaaaga agtcaatgat attttgcgca aaaaggtccg
    14341 tgaccctcgt gtggagaacg taacgatcac agatgtgaaa gttacggggg acttacagca
    14401 agcaacgatc tattacagca ttttatctga cttagcatca gataagaaaa aagcacaaga
    14461 tggattgaat aaagcatcag gattgattcg tcgagagtta gggcacaatc taagtattta
    14521 taagacacct gaattgttct ttgaacttga tgaatcagtt gtctatggga accatatcga
    14581 tgaattgctt cgcgacttga acaaagacta atcaaaaaat cccgcaaatc ctgtgaaatc
    14641 aggggttgcg ggattttttt gttttcatta agacgtatta cctaagagtt ccatgacttt
    14701 agtctggtag cgtgtcagct aaccaaaaaa gagaaaaaga aaagtaaaaa attcgacttt
    14761 cttttttcta tagtatataa atttttgcat atagataaag atcaagatac cgataacgga
    14821 agctagattg taatctattt tagtgacagt caggtatagc caagtaacta gaagatcagt
    14881 ggaacctgca ccataaaagt ttgagtttgt cggtccgttg acagttaaaa gaaaaatcac
    14941 gttgaagtta ttgatatttc cgattacgcc gcttcgattt ggtcacgatc caaattttgg
    15001 ataatccctg tagaaattag catagtagct gggataccaa ttcacatatt gacaaagata
    15061 acagagactt ttacataaaa cggatcaatc aggaaaggaa ttgctcgatc cagccccagt
    15121 tttccaacaa tgtgttaact ggcctagcgt cattcagcaa attatgcatg atgaggagcg
    15181 aaatgaactg cggaacagcc attgtgataa cgacaagttt tttggatcaa tgtaaaaaac
    15241 gtcagcgaaa ggaaaaattt cgtggttttt tatacctgtt catttggcta gatataaaat
    15301 ccaaacaaat gaacagaagt gcttattagg tttcaattgg gagtatctgc gctagaataa
    15361 gagtaataat gaaaaggagt gttatgtatg gattattcta gtaaagaata ctttgataaa
    15421 atgacggctt ggtggcgtgc tgctaattat ctttctgttg ggcaacttta tcttaaagat
    15481 aaccccttac tgagacgtac actgaaacca gaagatgtca aaaaacatcc aatcggtcat
    15541 tggggaacga ttcctggcca aaattttatt tatgtccatt tgaaccgagt catcaataaa
    15601 tatgatttga acatgtttta tatcgaaggg ccaggacacg gcggacaagt catggtatcg
    15661 aatgcttatt tagatggaag ttacacagag atctatccag aagtaacgga agatgagaca
    15721 ggaatgcaaa aattattcaa gcgattttca tttcctggag gcattgcttc tcatgcagca
    15781 ccagaaacac caggttctat ccatgaaggc ggagagcttg gatactctct ttcacatgca
    15841 gtcggagctg tattagacaa tcctgaagta atctctgctg tcgtgattgg tgatggtgaa
    15901 gcagaaaccg gtcctttagc tggaagctgg ttctcaaatg tctttatcaa tccagtgata
    15961 gatggagctg ttttaccgat ccttcattta aatggtgcaa aaatagccaa cccaacgatc
    16021 ttggcacgta aatcagatgg agaattagca aattacttta acggacttgg ctgggagcct
    16081 ttctttattg aaggaaatga tccagaaaaa ttaaatcctg ttatggctga aaaaatggat
    16141 caagcaatcg agaaaatcaa atccatccaa aaagaagctc gcctgaagac agcaacagat
    16201 gtcgtgatgc caaaatggcc agtattgatc gtacgcacac caaaaggatg gaccggtcca
    16261 aaagaatggg acggggaacc aattgaagga accttccgag cacaccaagt accgattcct
    16321 gtagatcaag aacatatgga tcatgcagat gctttactcc gttggctgaa atcctatgaa
    16381 ccagaaaaat tatttgatgc acaaggacgt attttagaag aaatcagaga aattgcgcct
    16441 actggtgacc aaagaatggc aaaaaatcct atcaccaatg gtggaatcga tccaagaccg
    16501 cttattatgc cagattggaa aaaatatact ttgcaatttg aaaaaccagg ctccgttaaa
    16561 gcagaagata tgaccgaact tggtaaattc gttcgcgaga tcattgagaa aaatccagaa
    16621 aatttccgta tatttggacc agatgaaaca aaatcaaacc gattgaatca agttttcaaa
    16681 acgacaaatc gccaatggat ggaaaaaatc gaaccagaaa atgatgaatg gctttcgcca
    16741 tctggtcgcg tcatcgacag tcaattatcg gaacaccaag atgaagggtt cttagaaggg
    16801 tacgttctga ctggacggca tggttttttt gcaagttacg aatcattctt gcgagtggtt
    16861 gactctatgt tgactcagca cttcaaatgg atacggaaat cacatgacct ttcttggcga
    16921 aaagattatc cttcgctgaa tctcattgca agctcaacag tcttccagca agatcacaat
    16981 ggatatagcc accaagatcc aggaatattg acacatttgg cagaaaagaa ggcggagttc
    17041 atccgtgaat atctgcctgc ggatgcaaat acattgctcg cagtcatgga taaagcattc
    17101 cgctcgtcag aaaaaatcaa tttgatcatc tcttccaaac atccgcgtgc tcaattttac
    17161 tcagcagaag aagcagccgt cttagtgaat gaaggcttga aaatcattga ttgggcttcg
    17221 acagcaaaag aggaggaacc tgaattggtc attgctgctg caggaacgga atctaactta
    17281 gaagcattag cagctgtaac tttgctgctg gaagaattcc caaaactaaa aattcggttc
    17341 atcaatgtcg tagatttatt gaaattacgt catccaagtc aagatccgcg tgggttgagc
    17401 gatgaagaat ttgatcaata ttttacaaaa gacaaaccga tcttatttgc tttccacggt
    17461 tatgaaacat tggtccgcac gattttcttt gatcgtcata accatcattt aatgattcat
    17521 ggctacaaag aaaatggaga tatcacgaca ccatttgaca tgcgtgtagt aaatgaactt
    17581 gatcgttatc atttggcaaa agacgcagct ttaaaaatca aaggaagtca agcagaagat
    17641 tttgcggaaa aaatggatca gaaattacaa gaacatcaaa actatattcg tgaaaatggt
    17701 attgatctgc cagaagtatt ggattggaaa tggaaaaatc ttgaccaata aaatgataaa
    17761 atcgatcccg caaaacagaa ttttttacat tgtattattt gtcaaattaa g
//
LOCUS       DACDAF010000057        17494 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.057, whole genome shotgun sequence.
ACCESSION   DACDAF010000057 DACDAF010000000
VERSION     DACDAF010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.057"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(59..187)
                     /locus_tag="IVZ69_001817"
     CDS             complement(59..187)
                     /locus_tag="IVZ69_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HAP8183896.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="IVZ69_001818"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="IVZ69_001818"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP8183897.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="IVZ69_001819"
     CDS             complement(1674..2729)
                     /locus_tag="IVZ69_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP8183898.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="IVZ69_001820"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="IVZ69_001820"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HAP8183899.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="IVZ69_001821"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="IVZ69_001821"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HAP8183900.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="IVZ69_001822"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="IVZ69_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HAP8183901.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="IVZ69_001823"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="IVZ69_001823"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HAP8183902.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="IVZ69_001824"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="IVZ69_001824"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HAP8183903.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="IVZ69_001825"
     CDS             10491..12050
                     /locus_tag="IVZ69_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HAP8183904.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="IVZ69_001826"
     CDS             complement(12161..14092)
                     /locus_tag="IVZ69_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP8183905.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="IVZ69_001827"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="IVZ69_001827"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HAP8183906.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="IVZ69_001828"
     CDS             complement(15021..15773)
                     /locus_tag="IVZ69_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP8183907.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="IVZ69_001829"
     CDS             complement(15932..16141)
                     /locus_tag="IVZ69_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183908.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="IVZ69_001830"
     CDS             complement(16152..17480)
                     /locus_tag="IVZ69_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183909.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
BASE COUNT         4580 a         3788 c         3170 g         5956 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct cttt
//
LOCUS       DACDAF010000058        17216 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.058, whole genome shotgun sequence.
ACCESSION   DACDAF010000058 DACDAF010000000
VERSION     DACDAF010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17216
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.058"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(163..708)
                     /locus_tag="IVZ69_001831"
     CDS             complement(163..708)
                     /locus_tag="IVZ69_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP8183910.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(720..1412)
                     /locus_tag="IVZ69_001832"
     CDS             complement(720..1412)
                     /locus_tag="IVZ69_001832"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HAP8183911.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(1431..1715)
                     /locus_tag="IVZ69_001833"
     CDS             complement(1431..1715)
                     /locus_tag="IVZ69_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183912.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(1728..2291)
                     /locus_tag="IVZ69_001834"
     CDS             complement(1728..2291)
                     /locus_tag="IVZ69_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HAP8183913.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            2519..3181
                     /locus_tag="IVZ69_001835"
     CDS             2519..3181
                     /locus_tag="IVZ69_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     protein"
                     /protein_id="HAP8183914.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            3305..4501
                     /locus_tag="IVZ69_001836"
     CDS             3305..4501
                     /locus_tag="IVZ69_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HAP8183915.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(4602..5978)
                     /locus_tag="IVZ69_001837"
     CDS             complement(4602..5978)
                     /locus_tag="IVZ69_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8183916.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(6015..6881)
                     /locus_tag="IVZ69_001838"
     CDS             complement(6015..6881)
                     /locus_tag="IVZ69_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HAP8183917.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(6970..7995)
                     /locus_tag="IVZ69_001839"
     CDS             complement(6970..7995)
                     /locus_tag="IVZ69_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP8183918.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(8013..8687)
                     /locus_tag="IVZ69_001840"
     CDS             complement(8013..8687)
                     /locus_tag="IVZ69_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8183919.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(8871..9764)
                     /locus_tag="IVZ69_001841"
     CDS             complement(8871..9764)
                     /locus_tag="IVZ69_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP8183920.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(9838..11535)
                     /locus_tag="IVZ69_001842"
     CDS             complement(9838..11535)
                     /locus_tag="IVZ69_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HAP8183921.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(11528..12841)
                     /locus_tag="IVZ69_001843"
     CDS             complement(11528..12841)
                     /locus_tag="IVZ69_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP8183922.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(12841..16359)
                     /locus_tag="IVZ69_001844"
     CDS             complement(12841..16359)
                     /locus_tag="IVZ69_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HAP8183923.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(16652..17110)
                     /locus_tag="IVZ69_001845"
     CDS             complement(16652..17110)
                     /locus_tag="IVZ69_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP8183924.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
BASE COUNT         4867 a         3852 c         2971 g         5526 t
ORIGIN      
        1 aaaaatataa cttaagttgt tgataataaa gagatttatt aacgtaaaaa gaataagttt
       61 ttttaaaata acgtataaaa aagagcataa aacaaagtcg tttgttttat gctcttcttt
      121 tattattttg tgctttttat tttatcaaat cactttgttt ttttataaaa tttctgcgcc
      181 tagtgtggac tcaaaatgtc tcaatgccca ttcatgtcca acgggatcga aacttgccac
      241 ggcatctttg aaaatatgga gtttgtatcc tagattatac gcatcgactg ctgtatgcaa
      301 cacacagata tctgtacata cgccggtcaa ataaatatct gtgatctggc gttctcgcaa
      361 acggatgtct agatctgttc cactaaaagc ggaataatgc cgtttgtcta tccaataaac
      421 attttcctct tgctcatagt cttggtataa actttttaaa gagccgtaca attcccgtcc
      481 acccgttcct atcacattat gcggaggaaa taagcggttc tccggatgaa aggaatcttt
      541 tggatcatgc gcatcaatgg caaaaacgac aaaatccttt tgatcaataa acttctttgt
      601 atgagcagtc agcttttttt caattacttg tcctgctgtc ccagtagtca gctttccatc
      661 ctctgcaaca aaatcatatg tgtagtcaat cgagatcaat gcgttcatct tagtcctcct
      721 tatacgagat gtttgacaaa ttcgatcacc atttctgctg atcgtttgcc tgcgtcttcg
      781 ataaattcgt caaagctttg tgtcgccgag tgatctgctg tgtcgctcat tgcacgtacg
      841 atcaaaaatg ggatattgaa ctgacgagct gtttgtccaa cagcggctcc ttccatttcg
      901 caagctaatg cttcagggaa attcgttaag atttctttga ttttatctgg cgagtcgaca
      961 aatgtatcac ctgtaacgat caatccttct tttgcgttca aattcgttgc ttttgctgct
     1021 ttaaccattt cactgcgcaa atatgtgctt gcttcataat atagaggcat tcctggtaat
     1081 tgtcctgggt tgtagccaaa tcctgttgca tctgcatcaa aataagctac tttgtctgat
     1141 ataacgatgt cacctacttg taagccttca ccgattccgc cagctgaacc tgtattgatc
     1201 accatgttca cgccgtattg ttggatcaac agacttgtgg taatagatgc taagactttt
     1261 cctataccgg aacgtacgac gatcacttcg tggttaccta atgaacctga aataaataaa
     1321 gcgcctgcgc gttcccatga taatggttcg cttaggttct ctctcaaaat ttttacttct
     1381 tcttccattg cgccgataat accgattttc atctttttaa ttccttcttt ctatataaat
     1441 gcgattgcta aaaaaaccac acataacatt aggataacaa taataagaga tttcatcaaa
     1501 aaagagttcc atttggtcgt cttttcccgt tcgctgatcc ttgttttcgt gattggttta
     1561 ttctttttgc tttctttacg ataaaagctg gcaatctttt tttcttcttg ctgataagct
     1621 gtttctgctt ttcgctgttt ttttaatgac tcgcttgctt gtgcttgttg tcgcttgcga
     1681 agttcgcttc gcgtaataag cggtcctttg gccataagcc gatccctcta ctttcctttg
     1741 gtcaatagtt cccagtattg aatcgcataa atcgtctttg catcacaaat caactgatct
     1801 ttcatcgctt gttgcgcctc ttcaagagtt agatgataca actccagtac ttcgtcttca
     1861 tcttgtgcta aaggattctc gaccttctct accccttgtg catgataaat atgaaggact
     1921 tcatttgcaa aacctggtga aagatacatc gaagtaagat ggctcagcga cttcgcacga
     1981 tagccagttt cttcttctaa ttctctagct gctgtcattt cgggattttg tccttctcct
     2041 ggatcgattt ttccagctgg aatctccaaa atcacttttt ctaaaggttt tcgaaattgt
     2101 ttgacaagaa gcagacgatc ttgttcgtca aaagcaatga tcccgacacc gccaggatga
     2161 aataccagtt ctctcttcga agttcctcca tctggcaaac gaacttcgtc tacagcaaca
     2221 tcaataattt ttccgctata gatttctttg cgactgattg ttttttcttc aaattgctca
     2281 ttgttcagca tatcttctcc tgctttcttt gtaatcataa ctgctttttt ttcatttttc
     2341 aatttttctc aaaaactcct tattagttta ccatagataa accttagatt ttctctaaat
     2401 atagaaaatc cttctttagt ccgatactct ttatagtagt ccgtatgcta aaataagtat
     2461 gtaatcgaat aacgaaaaga attcaatact caacgataaa tgacatggag ggtttattat
     2521 gataaaacga aattggccgt ggcttctagc attggtcttg ctatttctct ttgtccgaaa
     2581 caatagtttt tcttttgttc taggactttt attgataggt gtagttttag ttttgtgggg
     2641 actctttggt tcgcgcagga aaaagggaaa acaagaagaa attcctgcac tgactgacga
     2701 acttgaaact cactatgaaa aaagcggtat gacagcgaat gaaatttcat tttttcgaca
     2761 aacaatgaat caaacaaaaa atgagatcaa tcaattgcaa atgaatatgc agcagacagc
     2821 caaacttaaa gcaatcgatc tccgccatga tccagtcaaa gcagcgaaag ctttattcaa
     2881 agaattggtg aaagaaccaa accgactgca tgaagcaagt cagtttcttt atacgcatct
     2941 gccgaatcta gttgatttga caaataagta taatgagatc aatgaccatg agatcaaaaa
     3001 caaacagacc tatgaaaaac tagaagaaag cgcgcagatc atcgaccagc tgtcagcttt
     3061 aatcgcacaa gattatcaaa aattcgttgc tgaggatcta gatgatatcg acgtagagat
     3121 atctgttgcg aaacagagct taaagcgtga taataaatat gaaccagaac aaaaggatta
     3181 actcttttgt tcataaaaga agactcggaa cattcagatg atgtctggct gtttcgagta
     3241 ctttttctaa agtagagaca ttcatgtaag aatcgagaac agattcaaca aggaggaatt
     3301 ttttatggat cataaaccga ctgaaacaaa agatgttaca ccagttaacg atacacttga
     3361 agatttattg aacaacccgt tttcaactcc aacagatacg ctgaccactt cacaacaagc
     3421 ggagattgat cagctccaag agcaacagac agctgctcgt ttaattgaca aactaccggc
     3481 ggaacgccaa gaacaagcta aacagctagc agcaaaaatc gatgctaatg atgcacagtc
     3541 tgtcatcagc tacggatcgg ctgcccaagc aaaattaagt gaattctcac aatcgatgtt
     3601 gaatcatgtg caagcacaag atattggtcc tgtaggagat tccttaactg aactgatgta
     3661 tcgtctccaa gaagccaatc ctgacgaact gcgtgccgga gaagggaaca tcttccagcg
     3721 tgtcttcggg aaggtcaaac aatcgatcta tgaagtgaca gcaaaatatc aaaagattgg
     3781 tgcacaaatt gacaagattt cagtgaaatt agataaagaa aaagacggtc tgctaaaaga
     3841 taatctgatg ttagaacagc tttaccagaa aaacaaagac tactttgatg cactgaatat
     3901 ttatatcgct gctggagaat tgaaaatgga agaacttcaa acaacgatca ttccagaagc
     3961 gatgaaaaga gcagaagaaa ctggcgatca gatggatgtt cagattgcca atgattacac
     4021 gcaattccta gatcgtctgg ataaacgtac gcatgatctt cgcttagcta gacagatcac
     4081 gatccagcaa gcaccacaaa tccgtttgat ccaaaacaca aatcaggcct tggctgaaaa
     4141 gatccaagca tctatcgcta cagccattcc gctgtggaaa aaccaagtcg tgatcgcatt
     4201 gaccttgctt cgtcaaaaag atgcagtaac tgctcaacgc caagtctctg aaacaacaaa
     4261 cgacttattg aagaaaaatt cagaaatgct gaaaatctca gccatcgaaa cagcgaaaga
     4321 aaatgaacgt ggaatcgtgg atatcgagac ccttcaaacc actcaaaatg atttgatcga
     4381 aacaatccaa gagacattgc gtatccaaaa agaaggaaaa gaaaaacgtc gtcatgcaga
     4441 agtagagctt ggacacatgg aagaagatct gaaacaaaaa ctgttggatt taacccaata
     4501 gatcaccttt cgcttgttac taaaacaaac gcccaacaac agtttattac aactgttgat
     4561 gggcgttttt cttatctttc ttctaacttc tccattggag tctatttctc attcatcttg
     4621 ctgtgtccat agccatagcc aaaataaatg atcagtccaa taaccattac gataccgaac
     4681 acgatccatg tcacagtttg cagacgaagc atcaatacaa tacaagtcaa gatggagacg
     4741 attggcaata gcggaacgaa tggcactttg aattctccag cttttggttt gccaaacatt
     4801 tttctcaact tcagtaagcc tagactaaca agcatcaaat aggcgagcgc catgatattc
     4861 gttagttccg ctaatacatt caatgggaaa aatccggcaa agaatacagc tgccacacca
     4921 gcggcataag tcgctttttt cggtgtacga tgcttttgat cgatttctgt cataaactta
     4981 ggaagtaagc catccttgct gacagcaaac agtaaacgag caagtgaata catcatcgag
     5041 atcgttaccg tcagtagcgt taaaattgcc cctacagcga tcaccgcgcc cactgttcca
     5101 tgtcctacat acctcattgc aaaagccact gggtcattga ctcctagttc agtatacgga
     5161 acgattcctg tcaagatcag cgtcacgatg atgtaaagga cagtagcaat cagtatcgaa
     5221 ccaatgattc ctcttggcac atctttttgc gggtttttga cttcctcggc tgccattgca
     5281 acggcatcaa atcccaagaa agcaaaaaac acaagagctg caccatctag cacaccggaa
     5341 aaaccaaaag gcatgaatgg ctgccagtta tcaggtttaa cgaaaaatat tcctacaatg
     5401 ataaacaacg cgatgatacc aaatttgaca tataccatgg cattattcaa acgtaatgct
     5461 ttcttggctt caagcgacac gatgtaagtg acgaatatca ctacgagcac cgcaatcaag
     5521 tcaatgtatg taccattttc cggattgtac ccgccagtta atgcttgtgg aagttcggcc
     5581 cctaaacttt tcaaaaaacc ttgcatatag ccagaccatc cggaagcaac agaggaaacc
     5641 gctagtaaaa attccccgat caacaaccac cctgtcagcc aggcagcaaa ttcaccaaat
     5701 acaacataca gataggcata tggcccacca atcactggca ctcgcgaagc aaattctgcg
     5761 aaacttagtc cagacaaaat gacaacgatt gcagctaaga caaatgaaag tgacagtgct
     5821 ggaccagcat tttgattggc cgcaacccct gtcaccacaa atattcccgt accgatgatc
     5881 gcaccaattc caagcatgat caaatcagac gtttttagtt cttttttcat ctcactcgta
     5941 tgattgagat tgatctcttt cttacgaaac aaatccattg aagttcctcc ccattttagg
     6001 ttggaaaaca gcgattaaac tgttttcata taccctaaaa ggataccacc taaaatgact
     6061 aaaaggcaac caacaataac ataaatgagc tcttttttcg tttttctttc gccaaggatg
     6121 aaaatcccac ctaaagtaga gataatgatc cccatttgtg aaagtgagaa gccaacagct
     6181 aaaccaagtg atttgactgt tagaagcatg cagatgtttc ctaagcccca taataatcca
     6241 cagatcatgt ttttccacac aaactgatcg actttaactt tacggaaagc aaagaagctt
     6301 gcgcctaaga tcattccgat actttgaggt aagataattg acatcgcatc caaattcgcc
     6361 cagttgacga tgatggtata tacaccataa ccaatcgtag agaagatcaa tgctctaaaa
     6421 cccttaccaa aatcaagcat tttattatct gtatctattt ttccttcgtc atcttgtcgg
     6481 gcagtcaaat acgcaccgct tacaagaaga gctaaagcaa taataccgta tacataatct
     6541 ttcgtttgtg tccattcatg gaagaaaacg gctcccgcaa tcgtattcaa aattaattga
     6601 aaaccagtag acaatggtag ccctacagaa acacccatgt acttcattcc atggaactgt
     6661 ccattttgtc caacactcca agctaagccg gataaaaatc cgatcaagaa aatccaaggg
     6721 gtgattacag gactaacaac gaaaaagaca actaaagaaa acagaaatgc accgatcgtc
     6781 attcctagtg tttgttgatt ggcatcgcca ccaattttac cacttactaa accaatacta
     6841 ccccatgcca acatagggac taatgctatt aaaatttcca taaccaatct ccttttattt
     6901 cacatgataa gaaacttatc agcgaaaacg ttaacaacac aagcactttt tttcgtttct
     6961 aacgattttc taacgttttt cattataaaa atttaagatt gggaaaaata aagtcattgt
     7021 tgtccctttt ccttcagttg attcagccgt caaatggata cctaattttt cggccagatt
     7081 ttttgctaaa taaagtccta atcctgttga atgtgttttg ctaagtcgac catttctccc
     7141 agtaaatccc ttatcaaaga tccgtttcaa gtcttccgct gggataccga tccctgaatc
     7201 tttaactgaa aggctgactc cttgcgcttc cttttctatg ctcacaatga tgtttccgtg
     7261 atccggcgta tatttgatgg cattactaag caattggttg aagataaaag cgatccattt
     7321 agcatcggtc aaaacagtat gatcctcacc aacgatctcg tagcgaatat ttttttggat
     7381 aaaataattt gcctgactgc gtatcacagg ctgaatgatt ccttttagtc catattcttg
     7441 gatgaggtag tcccgcgaga aactgtcgag tcttgcataa tacaaaactt gttctacgta
     7501 ttcatcgatt tttgataatt cattttctag taatgtatac ttttgatcgt caatatcgaa
     7561 ctcgatcgaa cgaactagca atttagaagc ggaaagtggc actttgattt catggaccca
     7621 tgagtcaata taatcttttt ggtcttgttg attactgatt gctgattgca ttacttcttg
     7681 gtgttcacgg atcagctgat tgatatattc ttctaccagt ttttcttctt ctgtcctccc
     7741 accactcaaa taattttgca aaggggaagt tttttgtatg tcggctaatt ttccccacca
     7801 tcttctcttg ctcaagtaac cacccagcag ataaaaaatc agaaagacgc cctcaatcaa
     7861 agctaaataa gcaattgtgc tcaaatcaac tttgatgttt ggcgccagcc acatcacaaa
     7921 gatcgtcaat gcaataaaaa acagccatcc caagatcaat gtccactgat ctttcaaata
     7981 tttaaaaaaa ttcatcttaa ccgctcatcc tttcagggaa cgatatatcc ctgtcctact
     8041 tttgtttcga tatatccttg gatacctgcc tgttcgattt ttcggcgtaa ccgattgatg
     8101 ttgactgtca atgtattgtc atctacaaat cgttcgtcat cccacagtgc tcgcagcaat
     8161 ttttcccgac ttaagatctt tccattgtgc ttcatcaaaa taaataatag acgatattca
     8221 tttttgctca aatcaatgat ctctccgttg atttccatac ttccgttgtc aacattcaac
     8281 gtaatgccat tgtggctcat catttcacta gataattctg tgtagttgta agaacggcga
     8341 agtaatgcat tgatttttgc aatcagtaca tcgatttgga aatgttttgt cacaaaatca
     8401 tctgccccca tgttcatagc catgatcata tccatattcg tattcctgct ggagataaaa
     8461 atgatcggta ctttcgatac ttcacgtatt ttttgacacc aataatagcc atccaaaacg
     8521 ggaagattaa tatctagtaa tacaagctgt ggttcttctc tttcaaagtc tgagaacact
     8581 tgattgaaat cggtcgttcc aaaggtttca aattgccatt tctcaagttc ctccatgatc
     8641 aattgtcgaa tgatctcttc gtcttcgact accatgattt ttgccataaa aaatccctcc
     8701 atctttcttc ttgctactac aatatcaaag aagcccttgt gaaacaagtt ggcttacctg
     8761 gaaaatgtca ttttagcaaa cgttaaaaaa aactggaaat atgcgattta atcgcgtttg
     8821 tctcttccaa gcagcttaaa tttattatgt tattcttaat aattggtcta ttatctgtta
     8881 tttttctttc gttgtttttg tcttttaaat tttcgataac accaataacc gaaaagcgtt
     8941 agcactagca atatacctag aaggagtata agtaatcgat aaagatggta tttttttgtc
     9001 tgttctatct ttgaagagac ttcttctgta aagggaactc gtcttcctgt cactagtaat
     9061 cggtgagtgt tcacggtgta aggtgtacaa gtgataagtg tgactagatc ctgcttttct
     9121 ctaattgcta atgtatttgt ttttgttgga aggacaacaa ttttctcaac gacttcataa
     9181 gcgagcatcc gaccatacac ttcaagatag aatcggtcat cttgctccat ttcttcaaga
     9241 tccgtaaaga gttttttctc agcaataccg ctatgggcgg taatcacgga atgtgtactc
     9301 tctcctccag ttggaaaaga ggtgccttgc aggactgtcg ctcctctatc taacaaaaga
     9361 tcattcgttt catcaaataa aggcaagcta acattgattt tcggaatata gatggctccg
     9421 atcatatgtt gttcgtaata ttcttttcct ggattttgga catttctaac cgcttgctca
     9481 aaaggatctt tgacttgtcc cattcctggg attactgatg tatgagcaag cgtctgattt
     9541 ttcttttcat gcactgctaa ttgttgctca tgtttttctt ctttatcgcg ttcaagctgc
     9601 ttttgataat tctcgatcct tctttgatcc aaataattgc tgagagcatc tgctaaaaat
     9661 ggatatgtaa aaactgcagc tccggcaaga aacatcactg ccataaataa ttgtaataaa
     9721 agactgattt gggtttgagg tctattacct attttctttt tcattttctt caccttctta
     9781 tttaaaaaaa ctgcagcaac ctttataaaa ccgattgctg cagcttattt ttgttgctta
     9841 tacttcagac ttcattttag atttacggta ccagctgtac gctccaatca tcaaacttat
     9901 tccgattagt aagaatgcca agagcccgtt cccaccagta gcaggaagtg acccgcgttt
     9961 catattcggt actctttctg gccctggatt ttctactcct acgatctgaa tttcttcatt
    10021 atagcttcca taagagatga taaattcagt aaaggctgcc tcacctgttg gaagtacata
    10081 accttctggc gccatggtct ctttcatttg ataggttcca taatctaacc cttgaacctc
    10141 aaagtatcca tttccatctg cgacaaattc tgttgcttgt ccgcttgttg cccactcaat
    10201 tctatctgct cctgattcat aaacagctaa aggcgactcc cctttataaa atattgcgta
    10261 ttcagaacgg tcttcattcc acaattcgaa tcttgcatct ttaagcaatt cactgcttga
    10321 tgcatcatat ttttcaaact ttcttccacc tgttgtgact ttctctggcg gctctactcc
    10381 ttcttcataa tcaaattcat catttcgtcc gatttcaata accgctgtgt tgttatggaa
    10441 atcatccgct tctagttctg tggaaacctt caaattatac gtgatcgtta aatctcctcc
    10501 acgtgcatct gctaatctac ctaaagtatc tactttggct actccatttt cttctgtcaa
    10561 aatcgtcacg acaaacccgt tgcttactac ttctactata taatcttgtc cttttgttaa
    10621 aatcgtctcg ccggctcgca cttctatttc ctgatcataa taagttagac caactgtagg
    10681 cgtatctgtg attttgtaat ttttgataac agcgcttccg ttttcaagga cagaatcgat
    10741 gaaataagga ataggtgctg tgatcgtgta agaagccgtt tttcctcttt ctagatcaat
    10801 ataagaaatc gtttcttgtt ctccagcttc attaataatc gttacttgtc taaggtcgct
    10861 ttcctctaca ttcatctgtt tatctgcttc tctgatttcg tttttcggat acaaatgcac
    10921 atctgtattg tatgtgtctt tccatgtaga accatcccac acgccatcca ccatatcagg
    10981 catcatcact ggcatcataa caaccattgg agacgcgatt ctggaaatat gagctggcga
    11041 ataagtttct aagaaaagat agactttatc tctagaagaa ggtgcttctt ccgtcacttg
    11101 gacggtagag aataccgctt ctccagcttc attcgttgtt tgtttgtcaa tacttgtcag
    11161 tcgatatttt aaaaaccaac tttctgtgtg ccgtttttga atccattcaa tcgcttcggc
    11221 agaattaaga ccgtcttctc gttccggtgt taaaggatta tctcgaatca aatcgtaata
    11281 tacttccgtt acgtcaaaca aatcaaaatc gactcctgga atattttctt caccaaaatc
    11341 cgtagaaacc aatccgctat tcggtcgttc ttccggaaca gatgagaaac cttttttgtg
    11401 taatgtaatc gtcacttcac ttggtttttg tgcgacttct tcggctttga ctagttttcc
    11461 gttcccgaaa atccctattc ccgcagtaac gagtaacagt acactcattc ccgtgacaat
    11521 cattttttta ttcatttttt tctccccgtt ctttttttat taataaaaca gcacctaaca
    11581 ataaaagaat tcctagtaaa gaaatcaacg ttcttgcttc attcgtttgc gggaatacgg
    11641 accattttcc tgattgacct ggattgcttg gaccactcgg ctctttcggt ttgtccgttg
    11701 tttcttttac ggtctcgtta taaacacgtg gtgttgcgga ttcataggca gagactggaa
    11761 ctttcccgga ttctaattca gccatctcct gtccgttaac tactacatat tgtggttggc
    11821 cttttgcatc cacccaaaat tcagggatga tgacctcgat tctcttactt gcttcatcca
    11881 tctcgtaacc ttccacacct tttaattctt caaaataata ggtgccagaa ggcaagaaac
    11941 gttgtcctgt cgtaacaagg ccctctttat ccgaaatgaa tttgcttaca tttttgtcat
    12001 tcaaaggatc attgtctgct ggtttgatcc attgattttt caagtcatta gcaggagcca
    12061 tatctaaata atatttcccc ccttctatca tctgatatag agcaaaaaca gcaccttcta
    12121 atggttttcc tttttcagtt gttcctcttt gacgtccata cttgaagaag tatggatctc
    12181 ttagataacc gacattttta ggatagatat gaatctcttg cagttcctcg gttgattctg
    12241 tcgggtgata aattggcaaa atagcagcaa ttgggatagc tgtctgatcg atatcaacat
    12301 ccaatccaac ttctggatca atcgattctt cgaaaatcaa ataaactgca tcccgatctt
    12361 ggtttttctt aggtgctttg atacgtgcaa tcccgtctcc taatccgcca accgtatctt
    12421 tcccagttgt taccgaagtc cctatttgga caagcctttc ttctgtgatt agctgacgga
    12481 tattgtttct gttcgtttca gcgatttgct ggacgaattc tttaggagtc atgttttcag
    12541 cagctttttt ttcatgataa taatcggtca tgtcgtaaat ggcaaatgtc gctccattta
    12601 gtggcaccgt ctgtgaaatg atatctgctg tttcccctgc ttcctcagag atagccaagc
    12661 catcattttc atggtattca aattgatcgt tataatcgat atctcgaatc atccgtttat
    12721 gcaacacgaa ttccacgaca tcttcccctg attcttctgc cgacatcgca tgtggaagaa
    12781 ggactgctgc aagcggtagt aaaacaagta attgaagcat caaacacaac agctttttca
    12841 ttaccttgct ccctcctttt tagattgtct gacaaacaaa ccataggctg ctcctgcaag
    12901 cgccatgaag aatgcagcaa gcaggatata gaataatcgt ccggatcctc ctgtagcagg
    12961 caacggattt tcaggatcgt tcccgacact aagctgtaat ctgattcgat ttgtctccaa
    13021 aagttcatat tctaactctt gctgtagatc aggcgtctct gcttcttcgt ttggataata
    13081 cgaaatctca acttttagtg tacccgcttc ttttcctgga actacccgat cattttctat
    13141 gtcaggttct tctcgataac taatttctaa aataaagtaa cctggaagtt ttctatagct
    13201 gtcaggtgac ttcacttcct tgatccgata gaccccttcc aacaagtctg aagcattgaa
    13261 tagggaagaa tcgtttggat ctggtgccaa gcctccctcg atgatttcat actctcctgc
    13321 actattttgt ttctcaattg aaaattctgc gccttcaaga cgtcggctat tcatactgtc
    13381 aattttcaaa agttccaaat cgattggcgc tagttcatct tctaaggtta cttgtagtac
    13441 accatcgatg atttcatagc cttccggcaa gggagcagtt tcgtcttcga tgaccgtatc
    13501 ttcaatgata aacttacctt cttcattcag tgcaaactgg aacacttgat cagatagccg
    13561 atacccattt ggtgcgacag attccgagac ctcatattca ccaatagaca gatgcagagg
    13621 ttggtcgtaa tttaaatcga catacttttc tactcctacg gcacgagaat agaagtatcc
    13681 gatcccaggc aaacgtttcg attcttctgg ttctaacgga ttaccagtgt atgctcgata
    13741 cagcgggaag gaagaatccc ccactttcct gatatcgaaa cctgcaccat ctaatgtatg
    13801 gccttcatgg tctaattttc taactcggat ctcccgataa tcaaacgtat tgtaagcagt
    13861 gaatgctacc cataaacgat cctcttcatc tgttgtatac gtgagatatt gccaattttc
    13921 ttcacctgtt tgcttgagtt ggatagtccc tatagcatta tcgtaaagtc gcaagatcca
    13981 tgtgtcattt tcatcaggtt ctttgaaacc ttctgggttc tggctctcaa tgattttgta
    14041 ttctgcatag ttggtagttt cttcactatc cttataaaca aatgaatctg gctctccgat
    14101 tggatgaata actttctcac catccacgat tacatatttc ccgtcttcat ctactgaata
    14161 gaacgtgagt ctccctttct cttcctctac ttcgttcaca ccagaaagcc ctttcgctac
    14221 tggatatccg atttccagtc cgttaccatc tgtttcataa agttcaaact ctgcgccatt
    14281 gattggcata ttactgcctt caattagttt attgatattc atgtggattg gcttgaattc
    14341 atttcgcatt tccagtttga catacaactc atcatactct gtgccttcta tgttaggctc
    14401 ttgtacaaca gaaagcttgt gatattctcc ttcataatag gaattcggat ctttaccttc
    14461 cggtccgccg actctcgaac cagatgtata ttcatctaca agctcgtagt gacctaacat
    14521 ctcatcttcg ttggctgcat attttttgat ttggaattga tacgtctcat ctactaactg
    14581 ataacgtggt ggtccagcga tctctctgat ccaaaatatg tcgctgactg ctccagtttc
    14641 atctcctaaa atcggcatct tcgtttcaaa gatcgctatt ccgtccgtgg tagttttact
    14701 tgtttcgatt ggttcggctt ccccactctc tggattttgg tcatataatg caaattcgac
    14761 tccagccaac ggctcgccat tttgaccctt cttgctgact tggaaattac ggcctttatg
    14821 ttcgtaacga atggaagaag atgggaaata catccgtcca gtagtgatat cattctcata
    14881 atcctccagg ttctgaatat aggccatatt gttcactgtg caaaaatttc cgtcttgagc
    14941 tcccgcatca agttttactt ggtacttgat cctgaccatt tccccttcac ctaaagaaat
    15001 cggagaaaat ttataagctt ggttttcccg tccgacatac gttgtcggag tcgccactac
    15061 ttctggtggg gcttgtccat gacgttcttc atcccatatt tctggctctt ggtacttcat
    15121 gccgttttct cctggatcta gatggtaaaa ctgaatatct gccgatctgc cagctccaaa
    15181 tggtgagaca ttaaaaccag tttcatcata aagtgtggct tgctggatcg ttctcttgaa
    15241 ggtagaagag atatcctcca aggctgtaac aatgtcattc ttgttgttcg cattgtaata
    15301 tcgcggtgtt acgccatctt cttctaaatc agcaatattt ttcaatacat ttcgtccaat
    15361 agcatctagt cgttgtctcc cgctaacgtt tccatcgatt cctaaaccaa tggagaagat
    15421 acttggcggg ttctcttgat acttgttttt cagccaatga tgataagcaa ctgtgttgat
    15481 cgcagatgac ttttcttgcg aagtaggact gccattcgta ttgttattag aagaaccatc
    15541 accaacccag tgagtcgctt tattatctcc ttcttttacc tctccataac gatagtgtac
    15601 atttacttca tcttctggac ggttaaagtc agatgcatag gtaactggat gagtaaaccc
    15661 tgcattagaa gtattcccag aaaactcctc aaaatttctg aacaaaacgt cattatcttc
    15721 agcaatctta tcttccatca cagtccagtt gctccaagct ccattagtgc tcgtacgata
    15781 acttgactga atcggtgcat aactgaaggt cggtgtccca tctcccacaa cgattaggat
    15841 tttttctgga tttctatttt ctccgccatt gtctttatac aatgtttcat agccattttt
    15901 aagccctagt gtaagcggag ttcctccgat tggtgtacga tttaatgctg tattctcact
    15961 tcccgtcaaa cgattgatat catttgtcaa tggaaagatg tccgaactga tttgctcatg
    16021 gttattgata gctgtactat tatggtaaaa attcaccata ccgattcgaa tatccagact
    16081 cgggtcagag agcagatctt tactcatttc gtttactgcc tcaatcaacg cagcattttt
    16141 agtttgacta ttggtcccag cggttaattc actcatactc gctgacttat ctagaacaaa
    16201 aacgatatcg attggactga tttccttttt ctcgcccccg atgacatcta gatagacatt
    16261 gtaaagggtt gttgcatctt caggatgtag atcagatgct gtgctgcttg gcagaacagg
    16321 ttctacccat tttttgatgt acgccccgtt ataatccaag taactgtttt caaaattccg
    16381 ttcatttccc caaagctgaa cggtttgagc tggaacgttt ctatcttctt cgcctgcagt
    16441 tgatccatta ttagtagcat agtcgtaatt tcgccagttc gctcccccgt ttgtataatc
    16501 actatcatcg atcaagttct ctccgtcata tggcgagcct ttgtctcctt gatagcgttc
    16561 attgctttgt gtccaatttc ctaacacttt tgtatagtca ttcgttgtaa acttcatcta
    16621 ttctttcatc aaccaccact tgaagaggta gttacccttc gttcacatcg gggatctttt
    16681 ctgtttcaaa aatcaatgtg ccggtttctg cttcttttga ataaactttt ccgacatacc
    16741 attcttgacc atcgatcgtc tcgactttta ggtcttctcc atcttcatca taggaggata
    16801 gacctgttcc acgaacgttt tttacggtac caatcccggc ggctgccgca tcgattgcta
    16861 aacgtattct accttcattg gcactttcct ttttttcaaa agccagatgc cattcaaggg
    16921 tttcttcttt ttcaatatac ttcccttcaa tttttgcata gtcctcatct aagaatacct
    16981 catcctcctt tgtttctgtt gactcagcag ctacatccag ggtcgtcata tgatagactg
    17041 actggaaata tggtccaaat agcaaactga cagttactaa ctgcaaaagc ttcaatttta
    17101 accctttcac atccttatac tcctttcaaa aatatttgtc ttctttcaca acaatcaaca
    17161 aaacaatgcc catctaatta taatttaatt taattttaat tttaaatcaa atgata
//
LOCUS       DACDAF010000059        17164 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.059, whole genome shotgun sequence.
ACCESSION   DACDAF010000059 DACDAF010000000
VERSION     DACDAF010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.059"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(36..845)
                     /locus_tag="IVZ69_001846"
     CDS             complement(36..845)
                     /locus_tag="IVZ69_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP8183925.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
     gene            1138..2574
                     /locus_tag="IVZ69_001847"
     CDS             1138..2574
                     /locus_tag="IVZ69_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HAP8183926.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            2744..3940
                     /locus_tag="IVZ69_001848"
     CDS             2744..3940
                     /locus_tag="IVZ69_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HAP8183927.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(4002..4187)
                     /locus_tag="IVZ69_001849"
     CDS             complement(4002..4187)
                     /locus_tag="IVZ69_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HAP8183928.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            4418..7732
                     /gene="dnaE"
                     /locus_tag="IVZ69_001850"
     CDS             4418..7732
                     /gene="dnaE"
                     /locus_tag="IVZ69_001850"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HAP8183929.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KRQLIYLLGEDNVVFK"
     gene            7900..8862
                     /gene="pfkA"
                     /locus_tag="IVZ69_001851"
     CDS             7900..8862
                     /gene="pfkA"
                     /locus_tag="IVZ69_001851"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HAP8183930.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            8936..10720
                     /gene="pyk"
                     /locus_tag="IVZ69_001852"
     CDS             8936..10720
                     /gene="pyk"
                     /locus_tag="IVZ69_001852"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HAP8183931.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(10755..11657)
                     /locus_tag="IVZ69_001853"
     CDS             complement(10755..11657)
                     /locus_tag="IVZ69_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP8183932.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            11843..12412
                     /locus_tag="IVZ69_001854"
     CDS             11843..12412
                     /locus_tag="IVZ69_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HAP8183933.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            12470..12649
                     /gene="rpmF"
                     /locus_tag="IVZ69_001855"
     CDS             12470..12649
                     /gene="rpmF"
                     /locus_tag="IVZ69_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HAP8183934.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            12819..14240
                     /gene="gndA"
                     /locus_tag="IVZ69_001856"
     CDS             12819..14240
                     /gene="gndA"
                     /locus_tag="IVZ69_001856"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HAP8183935.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDEAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
     gene            14433..15119
                     /locus_tag="IVZ69_001857"
     CDS             14433..15119
                     /locus_tag="IVZ69_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8183936.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            15116..16621
                     /locus_tag="IVZ69_001858"
     CDS             15116..16621
                     /locus_tag="IVZ69_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP8183937.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
BASE COUNT         5552 a         2980 c         3594 g         5038 t
ORIGIN      
        1 gtcacaacct cttttttgtg gaatctaatt ctctattata gtttaagtag tttttccaga
       61 taaacagcta aaccgtcttc ctgattgctc aaaggagtga catcatttgc aatgcctttg
      121 agttggtcag taccgttagc catagctact ccccaacctg cataatccaa caattccaaa
      181 tcattatgct cgtcaccaaa ggcaatgacg tctttttgat cgatagacag gtagttagca
      241 atctcttgca cgccttttgc tttttggatt ccttttgaaa caatctctaa gatggcagta
      301 ggtccacccc atgtccgaac atcgacataa ctgccaaatt gacgtgttaa ttcagcagat
      361 acagctcctg caaaacgttt gtctgttcgg acaagcaaag atgtaggatt tgtcgtcaaa
      421 tttttaggag aaagcaaatt cttctctcct ggacgagaag aagcaaaaat tttttcatca
      481 aagaaatcaa aactgtcaat aaaaaaagta tcacgatttt cagcagcgat aaaatctaaa
      541 tttagctgct ttttttgcga taagatttca aaagcgattt cacgattgat caacgtttct
      601 ctttcaccat cccagtgctg attagggatg tgtactaatg cgccgttaaa attaaccatc
      661 ggtgttgtta attctaattg ttggtaaaac tgatggctca ttcggaatgg gcgtcctgta
      721 gcaatactga catgatgacc ggcattgatt gcttttttta gagtctcttt tgttttagat
      781 gtaatcatcg aatcttgatt gagggtagtt ccgtccagat cgatggcaat taatttttta
      841 ttcaataagg gtccttcctt cctcaactag catttgtttt agtctagcat attttaggta
      901 attaacaaga gcaatcagct attcctaaca aaaactacag ttatggctat ataaatagct
      961 aaacataagc taaacacgaa cgttaagtat tattttcgct ttttttgtta aaaaaacgtt
     1021 gaaaagcgaa tgaaacgtct atataatttg aaattgttcg atggatttgc cctattttac
     1081 ttatttttta ttattatagt tttccatcag aaaaaaattc agggagtgga actttttatg
     1141 gaaaagtttt tcggtttaaa gaaaaacaat acaaatgtat caactgaaat aatggcggga
     1201 gtaacgacat tctttgccat gagttatatc ttattcgtaa atccgacgat tttgtcagca
     1261 tcaggtatgc ccttccaagc agtatttcta gcgacaatca ttgcatcgat tattggtacg
     1321 ctggtaatgg gattgttcgc aaatgtacca tatgctcagg cacctggtat gggattgaac
     1381 gcatttttca cttttacggt cgtttttggg cttggttatt cttggcaaca agccttggca
     1441 atggtgttta tttgcggatt aatcaatatt tttattactg tcacaaatat tcgaaaaatg
     1501 attattcggg cgattcccga aagtcttcaa catgcgattg gtggcgggat cggtattttc
     1561 gttgcgtatg tcggaatcaa aaatgcagga ttcttatctt tttcagcaga ccagtcagct
     1621 atttcgagct ctgtcgttga aggcggaaaa gcgacaaatg ttacgataaa tggtggaatc
     1681 gtccctgcgt tagccaactt tgacaacgct cctatcttat tggctgtgat tggtttggta
     1741 ctgacagcca ttttagttgt aaaaaatgtc cgtggggcta ttcttatcgg tatcgtagcg
     1801 accacagtcc ttggtatttt tatgggtgtt gttgatttaa gttccattga ttggcaaacg
     1861 aattcgttag gtaattcatt taaagaatta ggaacaactt tcggtgcagc atttggttct
     1921 gaaggcatgc aatctttatt cagtgattct tccaagattc ctcaagtatt gatgacgatc
     1981 atcgcattca gtttatctga tactttcgat acgatcggaa catttatcgg tacaggacgc
     2041 cgcacaggta ttttctcaaa agaagacgag atcgcgttgg aagatggtcg tgggttcaaa
     2101 acaaaaatgg ataaagcact atttgccgat gcgatcgcta cttctgtggg ggctatcttt
     2161 ggtacatcga atacaacaac ttatgtcgaa tctgcagctg ggatcggggc cggtggacgt
     2221 actggtttga cttcagtagt agtggcagtg ctattcgcat taagtagttt attctctcca
     2281 ctgatcgcca ttgtaccaaa tcaagcaact gcgccagcat tgattttagt tggagtaatg
     2341 atgatggctt cttttgcaga catcaaatgg ctagatatgg aagaagcttt accggccttc
     2401 tttgcatcga tctttatggg attgtgctat agcatttcct atgggattgc agcaggattt
     2461 attttctata caattgtgaa agtaatcaaa ggaaaataca atcaagtttc tgttgctttg
     2521 tggatcgttg atattttatt cattatcaac ttcatcattc tagcaacaat ttaactaaag
     2581 agaagggatt ggaacagtat ttgttctgat ctctttttgt tttacataaa aagaacgtta
     2641 catataaaat gacctttgcg ggatttttct ctttttactg gcgagatcgt tgcttgttta
     2701 ttcgaaaata ggtatgataa aagagacgaa agagggatga tagatggaga ttaattggag
     2761 aaaaaattta gtgattgcgt ggattggctg ttttttcact ggtgcaagta ttagtttagt
     2821 tatgccattc ataccagttt atgttgagca actaggaaca ccaaaagatc aaatcgaatt
     2881 gttttcggga ctagcaatct ctgtgactgc ttttgcatct gccgtggttg caccaatctg
     2941 gggaaatcta gctgatcgaa aaggccgaaa actcatgatg atccgtgcag cagcagggat
     3001 gacattaaca atgggatctt tggcttttgt accaaacgcg tattggcttt tgatcatgcg
     3061 gttttggaat gggattttgt ctggatatat tccaaatgcc acagcgatga ttgcttcaca
     3121 ggcacctaga gaaaagagcg gatgggcgtt aggaacattg tctaccggag cgattgctgg
     3181 aaatctgatc ggaccttcaa tgggcggtgc actggctcag tggtttggta tggaaaatgt
     3241 attcttgatc acaggggctt tgttgatgat cacaacggta ttgaccattt tcttagtcaa
     3301 agaagatttc catccaatcg agaaaaaaga tctgataagc accaaagaaa ttttttcaaa
     3361 aatggatcat ctctctattt tgatcggtct cttcattacg accttgattt tacagatagg
     3421 aatcactacg atcagcccta ttttgacctt atatattcgt gaattgagcg gaagtacaga
     3481 aaatatcctt tttgtcagcg gcttgattgt ttcgatagct ggtgtttccg ctgtcttttc
     3541 ttcaccgaaa ctaggaaaac taggggataa gattgggaat caaaaagttc taattggagg
     3601 actcatttta tcattttgct gttatttacc tatggcattc gtcactacac cgctccaatt
     3661 aggtatactt cgctttattt taggcttttc aactggcgct ttgatgcctt ctgtcaatac
     3721 actgatcagt aagattacgc ctcaagaagg agtcagccga atctatagct acaatcagat
     3781 gtttagcaac tttggacaag ttttaggtcc catgctagga tcgacagtcg cgcatgctta
     3841 taattacagt gctgttttta ttgtgacaag tttgtttgtt ctgtcaaata ttcttctttc
     3901 tttattcaac tttcgtaaag ttcttcgcag cagattataa tggtggtgag gagtagaaaa
     3961 taaaaaagag cttgagaaat ctcaagctct tggctgtttt tttacgaatg ggcagaggtt
     4021 tcttttcttg gcgcaactgc accaatcaaa aggataatga cacccgcaat gaatgaaatg
     4081 attgttgtca aagtaaaatc atatgttccg cttgttaatg cagcaccaat ataaccgact
     4141 acttgaccta gaacgacagc ccagaataat gtaacgatat atcgcataaa gaacacctct
     4201 tttctatctt aattttacca gattttcttt gaatgtaaag aaacgagacc aaatctcaat
     4261 aaaatttgag ttcttgcgaa agaactcatt cctacagatt acaagcaagc aaatgaagtg
     4321 gaataatcaa cttcagcgcc tgctatctta atgaaagtaa aaggatcaaa ccttttaacg
     4381 ctagtgaatt ttaacgaaaa aaaaggcgga atgcaagatg tttttcccac aactttatac
     4441 aattacttct tattctcttt tacaaagtac gatacgtatt cgagaatatg tacaagaagc
     4501 aaaaaaacaa ggctacactt cattagccat aacggataaa gatgtcttat acggtgcacc
     4561 tgaattctat cgtatttgtg tagaagaagg agtacagcca atcattggat tacatcttag
     4621 ttatacttat gaagaaaaaa attatggctt gcttgcgtac gcaaaagatg aaataggtta
     4681 tcagcagctg atgaaacttt ccagccgaaa aatgatccaa gaaaaattgg aacttgcaga
     4741 aatgacagaa accgaccatc tagcgtttgt tgttccggca aatcattctg tttctgaggc
     4801 tttcaataaa gaggataact ttttcggtca ttggcagttt ttacttgaaa atgtttttac
     4861 tagaaatttt tatatcggct tgacagaaaa cacgcctgat caattgcctg aatggtatca
     4921 gtatgtgata aaagaaaatt attcgctttg tgcattacat cccatcgcta gtttacaaca
     4981 agaagaactt tttgcacttg aagtgatgaa acatatcaaa gagggaagcc aaataccttt
     5041 agaaaattta tctgcatctt taccactaac agcaaatgtc tatcttcttt cagaacaaga
     5101 aatgatcaaa cgattcgaaa aagcgggtct ttcccaagct gtaataggcg cccagcgttt
     5161 agctgaatcg atttcatttg aattccagtt ccatcagaaa ttacttccgc attatccagt
     5221 tcctaatgga aaacaagctg gagaatattt aagagagtta tgctattcgc aagtggaacg
     5281 ccgaatcact gactatacaa aggaatacca agaacgtttg gactacgagt tatctgtcat
     5341 ccatcaaatg ggattcgatg attatttctt gatcgtatgg gatgtaatgg cttttgctca
     5401 tagaaacaaa atcgttaccg gtgcaggtcg tggttctgct gcgggttcat tagtagccta
     5461 tgtgttagaa atcacagatg tggatccatt agaatatgat ttgctgttcg aacgcttttt
     5521 aaaccccgaa cgctttacga tgccagatat cgatttggat attcctgaca atcgacgtga
     5581 agaagtattg aattatgttc gagaaaagta tggacaatat catatggcac aaatcgcaac
     5641 atttggcaca atggcagcaa aaatggttct tagagatgca gctagagtgt ttggtttatc
     5701 gcaaagtgaa gcaaaccgct ggtcaaaagc aatacccaat caattgaaaa tcacattgac
     5761 ccaagcttat aaaacttcgc atcaattagt agaattagtt caggcaagcg aaaaaaacca
     5821 acttttattc aaaactgcag tgattttaga aggattgcca agacatgttt cgactcacgc
     5881 agcaggtgta gttatcagcg ataagaatct acttgaacta gttccgctcc aacgcggttc
     5941 tgatgaagct tttctgaccc agtatacgat gaatgaggta gaagcaatcg gtcttttgaa
     6001 aatggacttt ttaggactac gcaacttatc gattattgat tttactttga aagctgttaa
     6061 gcgagtagaa gggtatgaga tccgattaaa agagatcccg ctaaatgatg caaaaacgct
     6121 gctcttgttt caacgaggcg aaacctcagg agtatttcaa tttgaatctg ctggtatccg
     6181 gaacgtttta cgaagattag atccagaaaa catcgaagat attgccgcag tcaatgcatt
     6241 gtatcgacca ggccctatgc aaaatataga taccttcatt gccaggaaga aaggaaaaga
     6301 agccattcgc tacccagatg attcactgat cccgattttg aaaaacacat atggagtgat
     6361 cgtctatcag gaacaaatca tgcagatcgc ctcgactatg gctggattta cattagggca
     6421 gtcagatatt ctgcgacggg cagtgagtaa aaagaaaaaa gacgtattag atgaagaaaa
     6481 gtcgcatttt gtatcaggag cattacaaca gggatattcg gaaaaaacag cagcgaccgt
     6541 atatgaatat atcgaaaaat ttgcaaacta tggattcaat cggtcacatg catttgctta
     6601 ttcattcgtg ggattccaaa tggcgtatct aaaagcccat catccaggtg ctttctttac
     6661 cagcctgatg aattctgttc ggcataacac atcaaaattg aaagaatata ttgcagaagc
     6721 acgtaaaaat aaactcaaac tttcctcgcc gtccattaat caaagtaatt ccagttttga
     6781 gttggtcaat aaggaagaaa tcagattcgg actgacagcg ataaaaggta ttcggcgtga
     6841 ttttgtagaa gatatattaa acgaaagaaa acaaaatggc ccgttccagt cagtggatca
     6901 attcctcata cggatcgata agcgttggct gaaattagag ttactgcaat cactgacagc
     6961 agtaggagtt tttgatgaat tatctcctaa caggaaacaa ttgatgcttg atctcgaagg
     7021 aaaaatccaa aatatcgttt acagtggtgg aagtcttgac ttgctgggaa tcatggcatt
     7081 aaaagaagaa gaagtcgctg actatacact agaagaacgc ttgaagctgg aagaggagta
     7141 cttaggtatt tatttgtcag gtcatcctgc agaagggttt gatcgtcttc gtttagctaa
     7201 acaagttcag ctgattacag atatcgtccc taatcaacca gtcaatttat tagtgatgat
     7261 caaggaagtt agagaaattc ggacaaaaaa aggagaactg atggcctttg ttgaaggaac
     7321 cgacagtagt ggagaaattt ctgtcacagt ttttccaact ctttatcgta aatatcgtaa
     7381 tttgtttgcc gttgatcgag tgatctttgt tcaagggcgg agcgaaatca gcaaatataa
     7441 tcaggaactg caactaattg gagaaagctt tgctgatcct aaccagttag aagcccagta
     7501 tccttcacaa acttgctatt tgcgtattac agaagaacgg gaagatcccg agataatgaa
     7561 acaattacaa gtgatttttc agaaacaccc aggatatata ccagtagtta tgtatcacga
     7621 aaaaacgcaa cgaaaagtag ttctgtcaga tgcttattgg gtggatgaca gcaagagtat
     7681 aaagcggcaa cttatttatc tgcttggcga agataatgtg gttttcaaat aacttacggt
     7741 aaaaaatact acttgctttc attttttttc atttttttat ccgtaaatca agacaagtga
     7801 gaaaaataat gttagaatgt tagtcgtggt taacgcaaaa atggttgtaa acctaagtca
     7861 tacttaggat aaagtatttt aatgaggtga atgtttatta tgaaacgcat cggaattttg
     7921 accagtggcg gagacgcacc tggaatgaat gcagctgttc gtgccgttgt tcgtaaaggt
     7981 atttacgaag gactggaagt atacgggatc aattatggtt ttgccggttt agttgctgga
     8041 gatattcgtc gtcttgatgt ggcagatgta ggtgacaaga tccaacgtgg tggtacattc
     8101 ttgtattctg cacgttatcc agaatttgca actgaagaag gtcaattaaa aggaatcgaa
     8161 caattgaaaa aattcggaat cgaaggtcta gtggttatcg gaggagacgg ctcttatcat
     8221 ggcgcaatgg ctttgacaaa acgcggtttc ccagcagtag gtattcctgg aacaatcgat
     8281 aatgatattc ctgggactga tttcacaatc ggttttgata cagcaatcaa tacagtacta
     8341 gaatcaattg accgtattcg tgacacagcg acttctcatg ttcgtacatt cgttatcgaa
     8401 gtaatgggac gcaatgcagg agacatcgct ttatggtcag gtgtggctgg cggagcggat
     8461 gaaatcatca tcccagaaca tgattttgat atggcttcag ttgctaaaaa aatccaagaa
     8521 ggccgcgatc gcgggaagaa acattgcttg atcatcttgg ctgaaggtgt aatgggcgga
     8581 aatgaattcg ctgagaaact ttcagaattt ggtgactatc atacacgtgt atctatcttg
     8641 ggacacgttg tccgtggtgg agcaccaagc gcacgcgacc gcgtgttggc aagtaaattc
     8701 ggtgcttacg ctgtcgaatt gcttcaagaa ggaaaaggtg gattatgtgt cggtatccat
     8761 gacaacgaaa tcgttgcgtc tgacatcatt gatacacttg aaaacaacaa acataaacca
     8821 gacttatcac tatatgatct aaataattca ctttcatttt aagagtgaaa gaaaccaagc
     8881 tatttaagct gtgtacagct ttaaataaac aaaattgaat gggagagttt tttaaatgaa
     8941 aaaaaccaaa atcgttagta cattaggacc agcaagtaac tcagtagaaa ttatttctca
     9001 attgattgaa tctggggcaa atgtcttccg ctttaatttt tctcatggtg accatgaaga
     9061 acaattatca cgtatgacta tggtccgtga agcagttaaa aagacaggaa aagatgtcgg
     9121 tattctttta gatacaaaag gagctgaaat ccgtacaact gttcaaggca caacagaagc
     9181 tgattttggt cgtgcaggat acatcaaatt tgaagtagga gatcaaacac gcatctctat
     9241 ggatcctgaa catgtaggtt caaaagaaaa aatcgcggtt acttacccag gattatttga
     9301 cgatgttcac gttggcggac acattttatt tgatgatggt ttgatcgata tgcaaatcat
     9361 tgaaaaagac gaagcaaacc gtgaattagt cgtagaagtt aaaaatgcag gtatgctagg
     9421 atcacgtaaa ggggtaaatg caccaggcgt ttctattagt ttgccaggta ttactccaaa
     9481 agatgctgac gatattcgtt ttggtttaga caacgatatc gactttatcg ctgcaagttt
     9541 tgtacgtaaa gcacaagacg ttctagatat ccgcgaaatc ttagaagaaa aagacatgac
     9601 tcatgttcaa atcttcccta aaatcgaatc tcaagaaggt atcgacaaca ttgacgaaat
     9661 catcaaagtt tctgacggtg ttatgattgc ccgcggagat atgggtgttg aaatcccagc
     9721 tgaactagta ccaatggttc aaaaacgcat tatcaaaaaa tgtaatgctg ctggtatccc
     9781 agttatcact gctacacaaa tgttagaatc aatgcaagaa aacccacgtc caacacgtgc
     9841 ggaagcttct gacgttgcta acgctgtatt tgatggcaca gatgcaacaa tgctatctgg
     9901 tgaatctgca aacggggact acccagttga agctgtttca acaatggcac gtatcgacca
     9961 agaagctgaa aatgcattat cagaattagg tacattccaa ttgaacgaat tcgataaaac
    10021 agatgtaact gaaacaatcg gtttatctgt agctcgtgct gcaaaaaatc taggcgtgaa
    10081 aacaatcgtt gctgcaactg aatcaggata cactgcaaaa atgatttcaa aatatcgtcc
    10141 agatgcagat atcttggctg ttacttttga cgaacgcaca aaacgtggtt tgatgttaaa
    10201 ctggggcgtt tacccaacag ttgctgaaaa accatcaaca actgatgaaa tgtttgaact
    10261 agcagctaaa aaagctgttg aattaggttt cgcatcagaa ggcgatttaa tcttgatcac
    10321 tgctggtgta ccagttggtg aacgcggaac aactaacgtg atgaaaattc aaatgattgg
    10381 ttctaaatta ttagaagctc aaggcgttgg acaaaaatct gtcgttgcaa atgcagttat
    10441 tgcttcatct gctgaagaag ctgtaaaaaa agcaaaagac ggaatggttc tagttgtacc
    10501 atcaactgac aaagaatata tgcctgcaat cgaaaaagca gctgctgtta tcgttgaaga
    10561 aggcggattg acttctcacg ctgcagttgt aggaattgca caagatattc ctgtaatcgt
    10621 tggtgctaaa ggcgcaacaa caacaattac agaaggtgaa ttgattaccg ttgattcacg
    10681 tcgcggcatc gtttaccgtg gcgaaacaac agctatctaa tttagcttaa taaaaaataa
    10741 aaacagctct tcttttacga agagctgttt ttttgtgctg taacgaattc atggataact
    10801 tggactactt gttcttgaag aggcgtgacg atctgctgtg ttcgttttgc caatgaaatc
    10861 aagaagcgag gctgaacttc atctgaaaga gggaggcaaa ctaaatgatc ttcaggatgg
    10921 acagcaatct ctgccaaaaa accgataccc acattttctc ggaccatact ctttaaaatc
    10981 gtcaagtcat tgctttgata aacaactttt ggatgagtat gtgtttgttt agaaagctta
    11041 gtgaatgctg cggggtggac ataatgttcg ttcaatagta caaactgttc atctgctata
    11101 tctttgaaag agacagtatc ctgcttggaa agaggatgtg taggtggcac gacgatcatg
    11161 aaacgtttgt ccaaaagtaa ctctgtttct aaatattgat ccacgattgg ctgtgttgag
    11221 cctaatacag ctaaatcgat cctcccttgt cggatcatcc cgtataagtc ccgagagcct
    11281 ccatcggtaa tctcaatttg attcatcaat tcatgcttga taaagtaact tgacagttta
    11341 ggaaagtatt cattgccgat aataggaggc atgccaaaac gaagcttttt cttttgcaac
    11401 tgagtgattt cagctcttgc agtagaaatc tcttggagaa tggtttgtgc atggagaaac
    11461 agctgctttc cagaaggcgt gacgattaat tcgtgatgcg atcgatctct tgtaataagt
    11521 acggtgtcaa actctttttc aagacgttgt aatgcatatg taatagtagg ttggctcaca
    11581 cggaaataat tagccacttt cgtaaaattt ttttgtttga cgatttggac atagtattcg
    11641 atatctttcg tgttcatgaa gatcatccgc tcctttaatg gaataatgat tattgtaaat
    11701 gattctgagg atgatagcaa acagaggctt tctaataaag atttttctgt ttttttatga
    11761 actgcaaggt gtcaagaaaa tttcattgac aacatgcttt ttgccctgta taattgcttt
    11821 tgttgcttag gagtgatgaa aaatgaaatg gtctttattg gaattgagaa aataccagga
    11881 gacaccgtta acttttcatg agacgctcga cttgaaagcc gctctcatga agcgagacaa
    11941 tttaatactt gatgttgcgc cagtggaagt cgaaggtttg gtctcagttg ataagaaagg
    12001 ctatatcgtt cattacactg tgcagacgac tttgacagtt ccttcaacac gttcactaga
    12061 acctgttgaa ctgcccatgg atttttctgt agacgaagta ttcatgacag aagaacaatt
    12121 ccaaagtaga gatgaacaaa tgtctgcgga tgagattttg ctaattgaag gtccattatt
    12181 gaatttagca gagtcgattg aagacaacat cttattggcg attccaatgc gggtattgac
    12241 aaaagaagag gaagcagcaa cagaacttcc aaaaggcaat gattgggaag ttgtttccga
    12301 agaagaatac cagcgcagaa aaatggaaga agccgagaat aaaattgatc ctcgtcttgc
    12361 aaaactatct gaactttttg attctaaatc aaaagacgac gataacaagt aagattggaa
    12421 tatattgtgt ctaatttaga tacaagactt tacaaggagg tgtagcaaaa tggcagtacc
    12481 agctagaaga acatcaaaag ctaaaaaagc aaaacgtcgt acacactaca aattgacaat
    12541 caaagggtta aacgaatgtc caaactgtgg tgaaatgaaa aaaagccatc acgtatgtgc
    12601 aaattgtggt tactatgatg gtaaggacgt aatgtcaaaa gaagcttaat acattttaat
    12661 tagaaaatgt aaaacctcaa ggctaaccat ggagccttga ggtttatttt tttgtagtcg
    12721 gtaaataaaa aatatgttgt tctttagttt gcaatgtagc cgtgttaagc tataatgtaa
    12781 gagattaggg agaaatcccg tatgtaggag gagttcatat gtcaaaacaa caaatcggcg
    12841 ttgtcggtat ggccgttatg ggtaaaaatc tagccttgaa catagaaagc cgcggctatt
    12901 cagtggcttt attcaatcgt acaggggcta aaacaaccgc tgtagtagaa gaacacccag
    12961 ataaaaattt caaagcaaca tatacaatcg aagaatttgt agaatctatc gagaaaccac
    13021 gtcggatctt gctaatggtc aaagcaggac cggcaacaga tgcaacgatc caagagttgc
    13081 ttcctcacct tgataaaggc gatattttga ttgacggagg aaatacattc tttaaagata
    13141 cgatgcgtcg taatgaagag ttagccaact ctggcatcaa ctttatcggt acaggcgttt
    13201 ccggtggtga agaaggagct ttaaaaggac cttcaatcat gcctggtgga caaaaagaag
    13261 cctatgcgct agttgcacca atcttagagc aaatttctgc aaaagcagaa gacgaagcac
    13321 catgtgtcac atatattggc ccaaatggag ccggacatta tgtgaaaatg gtacacaacg
    13381 gtattgagta tggagatatg caactgattg ctgaatctta tgacttaatg aagaatattt
    13441 taaacctttc agtagaagaa atggctgata tctttaaaga atggaatcaa ggcgaattag
    13501 acagctattt gatagaaatc actgctgaca ttctgacacg taaagacgat gaaggaacag
    13561 gtaaaccagt agtagatgtg atccttgatg cagctgggaa taaaggaaca ggtaaatgga
    13621 caagccaaag cgcgcttgac ttaggtgtgc cacttccatt gatcactgaa tctgtatttg
    13681 cccgctatat ttctgcttat aaagaagaac gcgtacaagc aagcaagatt ttatctcgta
    13741 cgaacgattt tgagttcacg ggagacaaaa aagaattggt cgaaaaaatc cgagaagcgt
    13801 tgtatttcag taaaatcatg agttatgccc aaggatttgc tcaattacgt gtcgcttcaa
    13861 aagaatttga ttgggacttg ccatttggtg aaatcgcaaa aatctggcgc gctggatgta
    13921 tcatccgagc tcgattcttg caaaaaatta cggatgccta tgacaaaaat cctgagatcg
    13981 aaaatttatt gctagatgat tacttcgttg aaatcacgaa aaaatatcag caatcagtca
    14041 gagacgtcgt tgccttggct gtccaagctg gcgtacctgt accgactttc tcatcagcca
    14101 tcgcttactt cgattcatac agagcagaac gtctgcctgc aaatataatc caagcccaac
    14161 gcgattactt tggcgcacat acctatgaac gtgtcgacaa agaaggaatc ttccattact
    14221 catggtacca tgaagaataa tagtctttcg gctgttagga aatgagaaaa taaaaagagg
    14281 acgaaagagc tgaagtcgat tgttatgagt agacttcagc tcttttttaa aattgctatc
    14341 catgataaaa tgactataga tttttaagca tattatcggt ataatgatag agtttttaaa
    14401 aagccagtag aatagaaagg ataaaataat aaatgagcaa tattctaatc attgaagatg
    14461 aaaagaactt ggcacgattt gtcgagctag agttgaagca tgaagggtat aacgcagaag
    14521 tccactacaa cggccgaact ggtttagatg cggcattaaa taatgagtgg gatgccatat
    14581 tgttggatct gatgctccca gaattgaacg gtttagaagt ctgcagacgt gtacgccaag
    14641 tcaaaaatac accaatcatt atgatgactg caagagattc tgtgatcgat cgtgtatctg
    14701 gacttgacca cggagcagat gactacatcg tcaaaccatt tgctatcgaa gaattattag
    14761 cacgtcttcg tgcattgttg cgtcgaatcg atattgaagg cgataaaaat gtggctaaac
    14821 aaactactat tacttatcgc gatttgacta tcgaaaaaga aaaccgtgtc gtacgtcgcg
    14881 gaaatgaagt aattgaacta acaaaaagag aatacgagtt gctgcttact ttaatggaaa
    14941 acgtgaacgt ggtattagca cgtgacgttt tactaaataa agtgtgggga tacgaaacag
    15001 aagttgaaac aaacgtagtg gacgtatata ttcgttatct tcgcaacaaa attgacgttc
    15061 ccggggagga aagctatatc caaactgtac gcggaacagg ttatgtgatg cgctcgtgat
    15121 aaagccgaaa aaatcggaaa aaagagaact gaaagggccc tccttgacaa tcaagtgggc
    15181 ctttgcgagt tctttcttca tattcgttgt gtttacaatt ttcgctgtca ttacctataa
    15241 atcatctatc aatctgattg tggcaaaaga aagaaacaat gtagagcgta cgatttcaga
    15301 agtagcttct cgtttggcta actcggatga agaactgaca ttagtaaata cgtatcgtaa
    15361 tctgacgaaa gcgacaaatg acggagatga ggtcgtagat catacttcac tggtcgaagg
    15421 aaacttaatg aagatcgatt cctttatagc tgagctaggg cagccatcaa tggatcttta
    15481 tgtttatgat ttggacgaga acttgatttt taaaacccat gaaaacagtc gaaacctgat
    15541 tcagactaca cgtaaagttc caacgatcgt tacactagaa ggaaaaactg gctttttatc
    15601 tatccagcct atatattcta aaggtacaag agaaaagatc ggctatgcgc aaagcttcta
    15661 tgaattatct tctttctatg atattcgaaa taagctatta ttgactctta ttgttttaga
    15721 agttgtttct ttgatcttaa gtagtatttt aggtttcttt ttatcttctt atttcttaaa
    15781 accactcaag gtactcagag atacaatgga tactatacgt aaagatccgc aatcagatat
    15841 ccacatgcct gaaatcgaca caaatgatga attggcagat ttagctgaaa tattcaatga
    15901 gatgcttgac cgtatgcgtt tgtatattga acaacaagag caattcgtgg aagacgtatc
    15961 tcatgagtta aggacacctg ttgcaattat tgaagggcat cttagtctgc taaatcgttg
    16021 ggggaaagat gatcctgaga tattagaaga atcattaagc gccagcatgc aagaaattag
    16081 ccgtatgaaa agcttagttc aagagatgct agacttatca agagcagaac aagtagatgt
    16141 tcattatgcg aatgaaacaa ctaaaggaaa agaagtcacc tatcaagttt ataataattt
    16201 caagatatta tatccagact atgtgatcac tttagatgat gatttgacaa aagaagtgac
    16261 cctgcaaatt tatcgtaatc actttgaaca attaatcatt atcatattgg ataacgcagt
    16321 aaagtattca actacacgaa aagaagtcca tatctctatt tcttccactc tgaatgaatt
    16381 tgagatcgcg attcaggact ttggcgaagg aatacccaaa gaagacctta ataagatctt
    16441 caatcgtttt tatcgagtgg ataaagcaag agctagaacg aagggtggaa atggtctggg
    16501 gttgtctatc gctaaacaac tggttgaaaa ctataaagga cgtatcttag cagaaagtgt
    16561 agtagggcaa gggacaattt ttagaatctt tattcctatc gcaaaggcag aagacaagta
    16621 aagcatgtgc tttacttgtt tttttatata tccaacaaag aataaggtac aaaatacaag
    16681 caagttagaa attcagggat gtcattataa aaaaaactag cgaacaatta aatagaataa
    16741 catccgttaa ttaaacgtaa gtagctttta gatgaacgaa aaaacaatga aatgctgtaa
    16801 tattcgtgtt taaaaataat aaataaaaat agggaatttt ctattgcaat tttataaaga
    16861 gattgctata ttattatttg ttctaaatga ttcctttaag gtgtcactaa aaattataaa
    16921 aaatagggtt gacgcacttt tgatgtcatg ttataataac gaagtcgttt ggatgaggta
    16981 gctaataaag cttgatttta tcgaaaaaaa cttcgaaaaa gttgttgaca aataacaata
    17041 aagatgatat gataatcaag tcgctgctaa tgagtgacaa agacgtttag aaaaaataaa
    17101 caaagaagtt gttgacattc tcttctgaat ctgataagat taaagagttg ttgaaacaaa
    17161 aaga
//
LOCUS       DACDAF010000060        16944 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.060, whole genome shotgun sequence.
ACCESSION   DACDAF010000060 DACDAF010000000
VERSION     DACDAF010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16944
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.060"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(60..740)
                     /locus_tag="IVZ69_001859"
     CDS             complement(60..740)
                     /locus_tag="IVZ69_001859"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HAP8183938.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(789..1424)
                     /locus_tag="IVZ69_001860"
     CDS             complement(789..1424)
                     /locus_tag="IVZ69_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP8183939.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(1490..2893)
                     /locus_tag="IVZ69_001861"
     CDS             complement(1490..2893)
                     /locus_tag="IVZ69_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HAP8183940.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(2880..3911)
                     /locus_tag="IVZ69_001862"
     CDS             complement(2880..3911)
                     /locus_tag="IVZ69_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183941.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            3942..4163
                     /locus_tag="IVZ69_001863"
     CDS             3942..4163
                     /locus_tag="IVZ69_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HAP8183942.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(4328..5065)
                     /locus_tag="IVZ69_001864"
     CDS             complement(4328..5065)
                     /locus_tag="IVZ69_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HAP8183943.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(5218..6558)
                     /locus_tag="IVZ69_001865"
     CDS             complement(5218..6558)
                     /locus_tag="IVZ69_001865"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HAP8183944.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(6795..8318)
                     /locus_tag="IVZ69_001866"
     CDS             complement(6795..8318)
                     /locus_tag="IVZ69_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HAP8183945.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(8696..9307)
                     /locus_tag="IVZ69_001867"
     CDS             complement(8696..9307)
                     /locus_tag="IVZ69_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP8183946.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(9430..9555)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(9637..10353)
                     /locus_tag="IVZ69_001868"
     CDS             complement(9637..10353)
                     /locus_tag="IVZ69_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HAP8183947.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(10359..10928)
                     /gene="scpB"
                     /locus_tag="IVZ69_001869"
     CDS             complement(10359..10928)
                     /gene="scpB"
                     /locus_tag="IVZ69_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HAP8183948.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(10912..11709)
                     /locus_tag="IVZ69_001870"
     CDS             complement(10912..11709)
                     /locus_tag="IVZ69_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HAP8183949.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(11679..12050)
                     /locus_tag="IVZ69_001871"
     CDS             complement(11679..12050)
                     /locus_tag="IVZ69_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP8183950.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(12069..12956)
                     /gene="xerD"
                     /locus_tag="IVZ69_001872"
     CDS             complement(12069..12956)
                     /gene="xerD"
                     /locus_tag="IVZ69_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HAP8183951.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(13052..13525)
                     /locus_tag="IVZ69_001873"
     CDS             complement(13052..13525)
                     /locus_tag="IVZ69_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP8183952.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(13630..14493)
                     /locus_tag="IVZ69_001874"
     CDS             complement(13630..14493)
                     /locus_tag="IVZ69_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HAP8183953.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYGFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(14689..16788)
                     /locus_tag="IVZ69_001875"
     CDS             complement(14689..16788)
                     /locus_tag="IVZ69_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HAP8183954.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
BASE COUNT         4585 a         3588 c         2880 g         5891 t
ORIGIN      
        1 taaagcgatt tcgttcgttt tccttgaaaa aacaattgtt tttcattttt tttcttaatt
       61 taaaaaagaa gataaccttt tttcaaaaca acagctttta ttgctgcaac gacttctgga
      121 atcgatttgc cagtcgtatc gatacgaaca gcatcctctg cttgcttcag cggagagacg
      181 tcccttgttg aatcataatg gtctctttcc tgtatctctt tcgtcagtgt ttcaagatca
      241 gtcggaattc ctttttcttg gttctctttg aaacgtcttt ctgcacgctc acttacgctt
      301 gctactaaaa agattttcac ttctgcattc ggtaatacag ctgtcccgat gtctcttccg
      361 tccatgacaa cgccaccgcg ttcccctatt tttcgttgga cagcaactaa ttcttctctg
      421 acttttccat gtgcagagac ttcagaaaca gcttttgtga catctggttg acggatttct
      481 aaagtcacat cttttgatgc tatgaataca tgctgtccat cttcttgttg cgaaaaagag
      541 ataggatact ttttgatcag cgaaactagc ccttcttcat ctgaaaaaga tacattgttc
      601 gtaatagcta aataagttac tgcgcgatac atggcaccgg tatctgtata aatataattc
      661 aattcttttg ctaatatctt ggcaacggta cttttcccag atgaagcagg cccgtcgatt
      721 gcaatactga tttgtgtcat gatataactc ctttttctca gaaaaaaagc cgcaaagcgc
      781 ggctattatt atttaattct taattcttga ccagggtaaa gcataaagtt gtttggatct
      841 aagccattca attcaaacaa ttgatcagtg gtgatccctg cacgctcagc cacttgtttt
      901 ggaccttcgc ctgcttgaac agtcgttgtt gaaccggctg cagctgatga agaaggtgtt
      961 gtttctgctg cattgctgct tgaatcccct gcttgataag ttgcctcact tgaggaagtc
     1021 ggtgttgtct ctgctgcaat actgctttct gacgttacac ctgtatcttg agacacagta
     1081 gattcttccg cgattgtact agattctact gttgaagtct cagttgactc ctcttttgtt
     1141 gtacttgtag aactttctac tactgatgtc gaagtttcag aagaagttgc tgctgttgca
     1201 ttgttgcttg atccatttct gatccagaaa taagcacctg ctggaatagc gatacataag
     1261 accagtaaaa tcaaaaatag cgaaagaaat aatgtatttc ctttcttttg ttgtctctga
     1321 gaacttcttg atgaaacttc atcatctgta tcgtagattg gttgttccca tggttcttgt
     1381 gtttcgttat tttctgtaga ttgatgtcta tcttttctgc tcactgtttt acctcctaaa
     1441 ctctatcgtg tgtattatac cataggaaaa agtgtcttgt cctaaaaaat caatgttcca
     1501 tgtttttttt aaataaattt agtaaaatcg tttcccaatg aagttgttca gtcttagaaa
     1561 aaagcttcct ctttggcaga agttctgctt ttgctccatc aatatcacaa caattctgcg
     1621 gcttttcgga gagtttttcg ccaaaataag ctaagatgaa ttttctgcgg cagttttctt
     1681 cattaatata gcgaagcatc tgctgcaggc ggaattcttt ttctttttcc tgacgtttga
     1741 gccgttccac ccaattttct ggtttttcag actgctggat cagctccatc catttttttt
     1801 gcagctcatc aaagggagct tgctctgtgg catattccaa ataaagctca aaactttgtc
     1861 gctgttctct agaaagttga ttaaagaaat aatggatacg ttcatcccca ctttgataaa
     1921 aaagaattgc tgcactttct tcctgatctc tgcctgctcg accgatttct tgtacatagt
     1981 tttctagact gtctggcaaa tcataatgga ccacataacg gatatcagat ttatcgatcc
     2041 ccataccaaa tgcattcgta gcaatgagaa actgcagctg attttttaca aactgctgtt
     2101 gaagttgtct tctttgagct gcatcaagac caccgtgata gtatccaact gtaaaacgtt
     2161 ccctgaataa atgatacaat cgttcgactt ctttttttgt tgcacaataa atgattgccg
     2221 ctccttgtgc tctttccatg aagtgttcaa gttcttgttc tttttgctgc gttttccgaa
     2281 caaaaagcga gatattttgc cgattgactg attgtctgat ctcttttggt ggtcgatcaa
     2341 atagtacatg acgtatatct cttgctacta aatctgttgc tgtcgccgtt agtgccagtg
     2401 tgaccgggtt tcctaaaagc tttcggattt ttcctaactg ttgatattct ggacggaaat
     2461 caactcccca ttgagacacg caatgagcct catctactac atataacgca atattttgtt
     2521 ttttcagatg ctctaaaaga gaaggattag tcaacatttc gggactcaaa aacaaaaatt
     2581 tatattgcga tagatgacgg aggacgtatc ttctttcaga ttgcgaaagt aaactattga
     2641 aagcagctac tcgtttctcc cctcgttttt gtaattgcgt cacttgatct tccattagag
     2701 aaagcagcgg tgacacgatg atgaccagac cttccattaa ataccccgtc aattgatagc
     2761 aaaggctttt tcccgttcct gtaggcaaaa tagcgagagt atcttctcca tcaagcaacg
     2821 cctgaataat ttcttcttgg ccgggacgaa atgaatcaaa tccaaaatat ttttttaatt
     2881 catttattaa cattctgtat cgcttccttt ctcaatagat agatttgata caaacgaaat
     2941 tctccataat ctaattgtcc atctacattc cattcgctaa agcgccactc tcgcacggaa
     3001 tccttatttg gttccaaacg ttcgattgtt tctgcagaga gaatccactc gtatggaaaa
     3061 tcatcaaaaa acaaggccca ctcaataaga tgatctgtta ctgttcctct ttttaaatga
     3121 cggattgcca tgatctggtc aattgtctga ccattcataa acatctgctt ggtgatcatc
     3181 atgctttgat tgaaattttg ctgtaataat gaatcgatca aagcgtgcca aagcgaatct
     3241 ggccgttttt cgatttgtgc taacaaaagg tggatacatc tgctttgttg cagataaacc
     3301 gctgactcat cattgttttt tgccagctga taaggaagca gccctgttcg ctcatttcca
     3361 gataattggt tagctaaaaa atctgctgct tcttctggta tctccgaaaa cagctgcacc
     3421 aaactctcat acgcagtatc aatcaaaatt tcacgtggca attggctttc actaagccat
     3481 ttttttagtt ggaaagtata aaaaggactt gtctctgctg gaagatagtc ttgaataccc
     3541 gttgccagat tagaaattac ttgaacagca aatttaatga gccgccaact agtttcccct
     3601 gttctgccat agcggtcaaa acgcaaacca gtatgttcta tttgatgttc ggacaacata
     3661 tcagcccctg caggcgttag ctttgcttca ttttcattta tttcgatcca accttgctgc
     3721 gcaatttttt gcaaaatttg ataaaactta tcctgcttca attctggaaa actgttatgg
     3781 ataaacaaaa gttcgtgggt aaatccataa ataagtactg aagtcgttcg ttttcccaca
     3841 aggagttggt aaagagaact aatccgcagc ttgtgtcctg atgaaaatag cgataaaata
     3901 aaaacaatca tattattctc cttaagttag gatggttaga aatgtcacta ctatgtaaac
     3961 ttgtacctga acgctgtatt gcatgcggtc tttgtcaaat cgaagcgcca gatattttcg
     4021 attatgatga agaaggaatc gttttatttg cccaagaacc agaggctcat caacagttcg
     4081 tgatgccgga agaagaaaca tatgtaaaaa aagcgtatca aaaatgtcca gttcgagcga
     4141 ttttattaga aaataaaata taaatataaa cgaaacttta aaaacgtaca ctaagttctc
     4201 taaacttgaa aataagccgg gatctgtttc tcttgttccg tgaaatcccg acttattttg
     4261 aaagattcat ttgctatcta tagttaattg actagttttt tcacggaccc tataggaccc
     4321 atttatatta tttcaacttt ttcagccagt tttccaatgt attgacgatc acagtttgct
     4381 ggtctgcgtt agaaatttct gcctctccat ctcctttttg ctcaccatag ctgccaaaac
     4441 ctccatgatt tccgccattg attgatacat actctgttct ttccggtaaa tactgcttag
     4501 cttcttgata agcttcctga ttcaatactt tatcttttgt cgccgtgatc gataaaacag
     4561 gaacagctga ttctgtcaat gttccttttt tgtcgggata acttgccatg aagaataccc
     4621 cttttaaatg tttgtctgaa tgattcttat tgacataacg acttgccatt acgccaccta
     4681 atgaatggcc accgatcaca taatcggaat ttggaaaatc ttctttgacc ttatccgctt
     4741 tgtttccgcc catcactgct agatcaagtg gcattttgac aatagcgact gaaaagccgt
     4801 tttttgctaa atcttgcgcc caaatactat aactttctgg ctctacgaga gcaccaggat
     4861 aaaaaataag taatggagac tttccatgat tctttttctc tccttcaaaa aataagtaat
     4921 cttctttgtt ttttccttct tttaccaaca cttgcgcttc tgacgatggt tcgtacgtat
     4981 tttgctgtat atagtaataa ccggctccac cgagtaatcc taaaatgatg actaagccaa
     5041 ttagtattcg tctaaatatt ttcactttct cccacctttt ctatctgagt gacccctttt
     5101 tcttaatcaa gtatgattat accttaaaaa aataagagag aaatgcaaac tttccagcat
     5161 caaataaaaa aagacggaat atccatttga atatccgccc tttttgtatg tttattttta
     5221 tttagcacat aaacgataca cagcttctgc ataaatttcc attgctttat acatactact
     5281 taattcccat cgttcattcg cctggtgcat aaagtcagga gtatcaggga acatcgcacc
     5341 gaatgccaca cactggttca tcgtacgagc aaaagtagcg ccgcctgata caaacggttc
     5401 agtcatgtct ccagtaatat cgcgatatgt ccccaataga tttttcacta actcactgtc
     5461 tagtggcacg tataatgaat caaggaagtc aaattcttca taagtcaacc catatttttc
     5521 tgctgtttta gttaatttag ctactaaatc atctttcttg aatgtaacag ggattctcat
     5581 atctacaccg atttttgttt gttctggtgt gatttccaaa cttgcaaagt tcatcgttag
     5641 ctcgccggat tgttcatctt ctgttttgcc cacgacagct tcaccagttg cattttcttg
     5701 aactaatttt cctaagaaat tgattgggcc aaaatcaaat acttctgaaa gagcaattgc
     5761 cagacgagaa atagcattca ctccttgtgc tgcatctttc gcgtggatac ttttaccaag
     5821 aacgacgatg ccttcacctt gttcttcgaa atcgaattcg tgttttttca atgcttcttt
     5881 tacttcagaa agcttttctc cagagtaagg agctgcatca ggaacaacat tcaacgctcc
     5941 tccagctttt acagaaaact cgttcgttcc tggtcctgtc aagtaagctt gcaataagcc
     6001 tttttctgca taaattaaag gaaattcagc atctggcgca aatccttgcg taattccttc
     6061 ttctttttcg ttatattttt ctaaacaacg ccataaattt tcttcatctg taccaaagat
     6121 aaaacgaata cgtgtcttga attccacgcc agcatcaatc aaagctttga cggcatacat
     6181 tgccgcaata gaaggacctt tgtcatcttg ggatccgcga ccaactaacc agccgtcttt
     6241 tatagttgga tcgaatggtt ttgtttccca attattttcg tcccctgctg gaacaacgtc
     6301 catatgacac aagataccga ataattcatc tccagagcca atctctgaat aaccgtaata
     6361 gccttctgga tctttaaatg ttctaaatcc tagcttttca ctgatttcca atactttatc
     6421 caaagcttca atcacttttt taccgaaggg atgtccttgt cctgaatctg cttcatctag
     6481 tacggaagga attcggatca attcgctcaa tgattctaat gcttgttcat gatgttgttc
     6541 tgtcacaaat tttttcatga tattatcctc ctaatatgtt aaaaagggtc atgtcaaatt
     6601 cctccgacac aacctcttct tctcaaataa tgacgtttta agcctgctcc atcagcaagc
     6661 agaatgttct taacaaatga tgaaagaaaa aacactcact gaatggagct attgacttat
     6721 ccacgtgctt atcgatagcc gtttatcggt ttcttcattc ttatgataga ccttgtacct
     6781 gtatttgtct aggtttagaa cattgctgct acacctagga tcacacagat ggctacaaat
     6841 aatatcgcaa ttaatttacc ggtaaatttc caccacactg aaacatcgaa acgagcaatt
     6901 gctacagcac ccattacgat agcagatgtt ggtgtaatta agtttactaa accagatgca
     6961 gattgataag cagtgattac taaatcctta ccgacgccgg caaattcacc cataggtccc
     7021 atgattccca ttgttgcagc agctaagccg gaagttgaag gaatcaagaa tgacataggg
     7081 atatagaaaa taaatgtaat aatgatgaat acacttgaag ataatgaact taatccttgt
     7141 tcgccccaat gtaagatggt gtctgtgatt aatccattgt tcataaccac ttggatacca
     7201 cgagcaacag ctactacgat tgctacaccg atcaaatcag aagcaccagc taaaaattca
     7261 gagacaaatt cagactcttt catgccataa gtgattgcta ctacgatgga cattactaag
     7321 aataacatag taatttctgg gaagtaccag tcacctaatg gaagcatgct tttacctaga
     7381 accgtaccta gtaccggaag gtttgttaac cagtttgtca atgattcaaa aatcgtgaaa
     7441 ttcgcattca aggttgtcca aggaatcaaa ctgatgatca tgataccaaa agtaataaag
     7501 aacaatacat taacatgttt ttgttttttc gtgattactt cttgacgacc gattgcttca
     7561 atatcgaaat gcttcatatc ttctttacgt tggttgtata ctaatgattt tgttggatct
     7621 ttttcgatct ttgatgcata acgatacaca tatacaatag aaatagctaa caaaataacg
     7681 aacatcaaga atcgaagacc aataccttca cccatcgaaa tcccaacagc ttgtgaagct
     7741 acgcctgttg caaaaggatt taccgttgaa gctagacagc ctacttgaga ccctactaat
     7801 acgattgcta cagctactac tgtatcaaag cctacagcca tcatgactgg gatcagtaaa
     7861 gcatagaatg gaatcgtttc ttctgccatt ccgtaagtag agccgcctaa tgcaaataac
     7921 agcatcaata ctggaataag cattttttct tttcctttga atttcttcac aactgaagca
     7981 atcccggcat ctagtgcccc tgttttgttg ataataccta aaaatccacc aacaaccaaa
     8041 atgaagaaag agattgggat tgcagcaggt gtttctttag ttagctcccc cgctggtaca
     8101 cctagcatcc cattgattgg cgccatgaaa atatcccaca gcccttgagg attttgttgt
     8161 actcgttcat atgatccagc gacgatgttg cctgcatcgt ctacactata gtgcccagct
     8221 ggtataaacc aagtaagtac agcgattact gcaataataa taaataagac cgtatacgct
     8281 gaaggcattt gaaatttttt cttttttgtt tgttccatct tcttcttcct ttcttttccg
     8341 ttagagacaa caattttggc tctaatgtta ttttatcaaa aagagtatca gaacaaaaat
     8401 aataacacgc attttgtaaa acttttgttc aaaaagttcg tttttcccta ttccctcctc
     8461 ttttttcagg tttttaaagc tttcttcttt ttcattgtag cgtttccttt tttttataaa
     8521 caaacatttt cgtcttttaa aaggagaaga atttcacatt tgcaaagaat tgattgattt
     8581 ttatgcataa atcaaaaaaa tactcaaaac aaacaaataa aacgtttaca ttattgcatg
     8641 tcttgtattt ttttccaaaa aaaaagacca agaaatttct tgatcttttt gatatttatt
     8701 tgactgctgt atgacgttgt tcgaactgat gttgttttcg acttaaccat ggaagaagtt
     8761 gcgcatgcag cactaaaaag acagcactca cgatgaatcc tttgatcaag ttgaaaggaa
     8821 cgatcccaat cagtacatag tttgctaaag acatgcccag catctgtgtt gcgttcagcc
     8881 ctaaaaacat taagtaaaga ggcgtaataa cgaaataatt tgcgatactc ataaaaatag
     8941 ttagagcgat ggttcctgta atgacaccta aaaatttgtt tcttccttta tgctgtttct
     9001 ttacactaaa gaaataataa atcgggaatg taaagatcgt tgttgataag aaactagcag
     9061 tgtctcctac caaattatcc ggagaaaaac ctgtagtcag cagatgtaat actgaacgca
     9121 agaacgctgt tgcaactccg gccgctggac cgaataagaa catgctgatc aataccgaga
     9181 tatcactaaa atcgatcttc aaaaaactaa aagccggcat gatcggaaaa gcaaaatact
     9241 gtaaaactaa tgcgatcgca gcaaacatcg ctactgcaac cattttctgt acacgggtgt
     9301 tcttcatttg aaatcctcct gttaggactc ctcttcagcg aactttttga cgtttctctc
     9361 caaatgaaaa aactctattt tccagggaaa atagagttag agttatttga tcaagcgtcg
     9421 tcaaataagc tctatcttct ttatccagac tatactgtcg gtatcggaat ttcaccgatt
     9481 cagctatttt tttgcaaaat aggtcgtgga ctataaccac cggtcgggaa tttcaccctg
     9541 cccctgaaga cgaaccttat ataatttttg tttacatatt cattatacat atctattcaa
     9601 aaaacgcaac atctaacact tataaaaagt aagtgttcat tttgagtggt tcagcaaact
     9661 gctgacttct tttttgttca gttcacggta atccccagga cgtaggcctt gtaaagtcag
     9721 atctccgtat ttttcacgtt ttagtttttg cacaggaaga ccaactgctt gaagcatatt
     9781 tttcacttga tgattacgtc cttcgtggat cgtcaattcc acgatactgt ggtttgtctt
     9841 aggatccact gataaaattt ggaatttagc tggagatgtt tttcgtcctt cgatctttat
     9901 tccttttgtc aaaggtgcaa gcatcgattt tgtagcgatc ccttttacct ttgcaacgta
     9961 aactttatcc acttcatgtt ttggatgtgt caggcgctga gcaaaatctc catcatttgt
    10021 cagtagcaag atccccgaag tatcgtaatc cagtcgacct acaggataga tacgttcttt
    10081 taccatcggc aaaagatccg taacaacttt tcttcctttg tcatctgcaa cagcagaaat
    10141 aactccttta ggtttgtaca ataaatagta accgtattct tcttgataaa ttgggacttc
    10201 atccacttcc acagtgtcat gtttcccaac ttttatccct aattccctta caacttgtcc
    10261 gtttactttt acacgtcctg caaggatgaa ttcttctgct tttcgacgag aagtgatgcc
    10321 agcgtgggca attactttct gcaatctctc cattacaatt attctccttt attcattcca
    10381 tcaaagaata gatctggtga cacgtcttct tcaagtgaaa tttccatttc ttgtgtatca
    10441 ggcagttctt ctaatgattt caaaccaaaa taatctaaga agtagccagt tgttccatat
    10501 aatatcggcc gacctggtcc ttctactcta cctttttctt caatcagttt atgggcagct
    10561 agacgctgta ccgctcctga aacctgaact cctcgaatct gctcgatttc agctcttgtg
    10621 attggctgtt tataagcgat gattgctaag gtttcgacgg cggcttgaga taatgtgttt
    10681 gatgtccctt gcgcatatcg cttaagtaag ggagccagct cttttttagt cgttaataca
    10741 taatggcttt ccgtttcaaa aatatgcaaa gctgagtgcg agttttgagt gtaagattct
    10801 tttaattctt tcactaaact tgtgacttct gcttcgctga gatttaacag tccgcttaat
    10861 tcttcattac tgatcccttc ctcgccaaca ataaaaagaa gggcttcaag ttcacttaat
    10921 ttcgtcatgt tcggtatctc ctactgctgg ataaagcata attgattcat agttttcttt
    10981 ttgttgcgca atgatctgcc cttttttcat caattctagc aaagccataa aagtagtgac
    11041 aacttcactt ttagaaggtg actcaaaaaa agaatcgaaa gtacagccat gcgcatttct
    11101 ttttatacgc tcttcgataa ataccattcg ttcttcgatc gttgtgtcat cgggcgtgat
    11161 cgttttttcc actttttgag aaaatttctt acgttctaag attttctgca tggcacggat
    11221 caaatcgatt tttttgactt gtcctcgctt caacggcttt tcagcatccg ctaacccatc
    11281 gatgttcata ggttcttttg tgtaataaag acttcgttcc tctgcttttt ctgtcagtct
    11341 ttcagctgca tatttatatt tacggtattc taaaagctga gtgaccaatt cttctcgagg
    11401 atcttcttcc cataattctt catcgtctgt gacgaattct tggacaggaa gcaatgtctt
    11461 gcttttgatt gccatcaatg tagcagccat cactaagtat tctcctgcaa cagctagctc
    11521 gagtgttttc attgtatgga tataattcat atattgctcc gtgatcgtag cgatcggtat
    11581 atcatatata tcgatttcca tttgctgaat cagatgaagc agcagatcga gaggaccctc
    11641 gaatacatct aatttaatat tgatctccgt caactcattc actctttctt ctttttcttt
    11701 gctagccatt ttccaatgta aggctctgtg atttcagttg cacggatgga gacatccggg
    11761 tacttttcct gtaattcatc taacatttga aagcccatat tctcaccgcg ataagacgga
    11821 ttcaaagaaa tgtcatggat gatcagctga tcgttcgttg cccagtaaat accaataatc
    11881 ccttgaatgt tggttgaacc ttctggcgta aagaaaaaaa gttcataatc gtcttcagat
    11941 tcgtacgtat caatctcctt caacaaagaa gttttacctg tcagtttctt atggaaactc
    12001 aatagtccca tagcaatttt acggttttct ttccggtaat gtgttaacat cttctcacct
    12061 tcctatgact aagcccttgg aaaatgctgc ttataaacat ccgtcattct tttcttcgtg
    12121 atatgtgtat aaatctgagt cgtagagata tccgcgtgac ctaacaattc ctgtactgtc
    12181 cgcaaatcag ctccattttc tagcagatgt gtggcaaagc tatgccgcag cgtatgtggt
    12241 gttacttctt tgtaaatccc agcctctcgt actaactgct tcagattttt ccagattcct
    12301 tgccgagaaa gacctttccc atgattattg acaaatacat gcatttcaga tgcgtccttt
    12361 acaagtaatg gacgtgcttc gtctaagtag cgttccagcc attggatcgc ataatcacct
    12421 aaaggaatga tccgctcttt atctcctttt ccaactgtct gtaccagtcc aagagaaaga
    12481 tgaagatctc ccaatttcaa tccaatcaat tcactgacgc gcatcccagt agcatacatg
    12541 acttccaaga ttgcacgatc tcttatccct aacgtttttg tcgtatcagg tgcttcaatc
    12601 agcttttcta cttctgtcag agtcaatgta cttggtaatt tctgtgcttt cttcggcgta
    12661 tcgatatgtt gcatcggatc atgatcagtg atacgctctt gccgtaaaaa ctgatggaat
    12721 cttctgagac ttgagatcat ccgagtaaca gttgctgtcg cttttttttc ttcatgcaac
    12781 ttctccagaa aacggatgac taaaaagcga tcgacatcct gccatgaagc aattttctgc
    12841 tcctgtagaa aatgcaagta ctgttccaaa tcacgttcat agctttgtcg tgtattggcg
    12901 gacaatcccc gttcaatatt caagtagtgg agataatcgt tgatttgctc tttcataata
    12961 atccccctca tgcctctcta tcatatcaga taccgcttca ttctgatagt ctttttccat
    13021 aatctgagca aagaaaaagc cgtctagaca ctcagacgga ctggtttctt ttttcttttt
    13081 catagcattc ctgacagatt ccatggaacg ttagccgatg atcttttact aaaaaatgat
    13141 aacgttcttc tactacttgc tccacttcaa gtaaaagatc ctcttctact tcctcgatcg
    13201 tgccgcagtt caagcatagt aaatgatgat ggaaatgttt ggcgccttct tttctcaaat
    13261 cataacgggc taatccatca ttaaaactta ctttatcgac aattttcaat tctgtcaaga
    13321 tttcaagggt tcgataaaca gtagcaagtc caatttccgg actctttttt ttcactaaaa
    13381 agaagatttc ttctgcagat aaatgctctt tctcattttc caaaagcaca agcagagtag
    13441 cttctctttg cggtgtcagc ttaaaccccg cttcatgtag ctgctgtttt gtttttttca
    13501 tcgccgaaat agcattcatg accatttact caaccccaac aatttataat aattacaaat
    13561 aaaaaaagat ataacactat gttaattaaa attattataa gctagttaag aaaaacatgc
    13621 aagggattct caattagatt ttttgactag ttttgtcaca ccgttttctt gtgtaatcaa
    13681 tccttgtttc aaaagattac ctaatgcgcg cttaaatgct cctttgctga taccaaaagc
    13741 tttcatgatt tcttctggat ccgatttatc tgtaaagttg atttgctgat ctgcagaacg
    13801 ttctaaaatg gttaaaatca tttgtgcatc atctgatata gcttcatatg ctcttggctt
    13861 caatgaaaga ttcagtacac cgtctggtcg gacaccaatc actcgacctt ttatctgctc
    13921 gcctagacga ggttcattat atcgttcaga aggatggata aacccaagat agaaatcttc
    13981 cgttaaaacg tacgtacctg ttaatttcaa gcggtatgct gttcctatca catctttgtt
    14041 tttcatttct tctgttccat atttgcttaa agatttgaat attttttcat ctgctaaact
    14101 gccccaaata cggtcttttg catcaactct aagggaaatc atcaagcgat cccctttttt
    14161 aggccatagc tctgtcattg tcggcaattc atcaagagat acgacaaagt ctttatctgg
    14221 aagaccgata tcgacaaacg cacctaaatc ttttcgtgta gcagtaacga ttccaaaacc
    14281 gtaatgaccg atacggcttt taggaatttg tgtagtgatc cgattttcat gtttttgatt
    14341 ttggtaaccg aatccttcaa ctgcttcacc gattttgtgt tcaccttctg atttgcttaa
    14401 gccaaaggtt tgtccgtttt tttggacaaa gtagtttttt tcattttcat caataataat
    14461 acctgtaaat atagttgcta ataaatcgtt catttttttc tccctctata gtgaaaggtt
    14521 ttcttaatac atttctttgc tatcataaca taatgttatc tacttgaata gctgagcctt
    14581 ggtttggaaa ggtgaaaaaa ggagtatgac aacagttgtg tcatactccc ctttttcgaa
    14641 taaacggtgt taaacggcag gctcacagcc tctttcattt gcctaaaatt aattgctccc
    14701 atttcctccg aaccatccag ttttacagtt gatggttacg atgtaaaatg gcaaagcact
    14761 ttctccaatg cctttcatca atgcagattt tgttgaagtg gcatatagat tataatagcc
    14821 ttccccattt tcgattctgg ctttttctaa tctgtaacct ccttcaacga tatatccacg
    14881 ttggatacat gtagcaatca ctttgctttg gacacctggt gcccacgtcc atgctggatt
    14941 agatgcatcg gcaatatcac ttgctctggc agatttgatt ggctgattcg ctgagtttga
    15001 agaggaaggg gtcgaggatg ccgcttcttg ctgtgctgct tgtgcgaccg cagcttgttg
    15061 agcggcttga gctgcagctg ctgcttgagc ggcttgtttt gcttgttctt cagctgcttt
    15121 tttcgcttct tctgcttttt tcttttcctc ttcttctttt ttctctttat cagtgagcat
    15181 cttatctact tgtttcaatt gttcattcaa ctgagcagat agatctgtat ttttcacttt
    15241 ttctactgct tcttttgccg tcttgtattg gtcgcgtgtt gctgaatcca ctacttttcc
    15301 gtctttaaag actatagctg ttttttcttt agctgtttgc aattcagcat attgattttt
    15361 agcttctgtt tgtgcttgtt gaatcaattt tccaaaatct gtgttatccg tttcgattgc
    15421 ttggatctct ttatctgctt tcaacttgat gtcatctgct agatgatcat cgacgatggc
    15481 aggtgctatg aaccactcat tcactttttg gatatctcgg atcttagatt ggatatcttg
    15541 gtaagttgtt tctaactctg aatatccttt ttcattctta agactggata aatcattttt
    15601 tagttttgat aaatcttgat gaatcatatc tgcacgaata aattgatggt gatcatctgt
    15661 ataaaaggca gcaagtttct catgaagttc ttccatttgt tgctgtcttt ttgcttctgc
    15721 tgctacttcg gcttctactt tttgatgatg gtcataataa gcccagcttc ctccaccgag
    15781 tagaagtact gctgctaaaa cgagataagg tacttttttt gattttttct tttgcgcttt
    15841 atctggatct gttttttcta agtttgattc ttgatgtgtt ttttcagtat ctggcacgat
    15901 tgttattgat ttcgcttctg cttcaaacag cttaggctgg ttctcttctt tttctatttt
    15961 tgcttcaaga tcagtaccct ctttgcttac agattgattt tcagcatcgg attcactatt
    16021 tatttcatcg ggctctgttg actttttgtc tgtgttttcg agtatttctt ttttctctgc
    16081 ttccggcagt ttattcgttt tttccttttc taattgtttt tcagtaaata cttcagtttt
    16141 ttctgtgata tccgttttta cgtcttttat ttttactgtt tctttacctg tggcgttttc
    16201 tctatcagag tctttttcag tttcttgttc cttttctggc tctactttgt tttcctgtgc
    16261 aattttttca ctgatcattt tgagcagctc tttcgcgtgc tcttcttttg tatcttcacg
    16321 atgtgctttg atataagcgg atagtatcga attttcttcc tcattatcga cgatttcttt
    16381 cagttcagct actcttcttt tttgttttga ttcaagcgtt tcttcttgat tctttcctga
    16441 ttcttccgaa gtctcatgaa cagttgcttt cttctgttca tttttctcta tattagttac
    16501 ttgatcgtga gcaggtggtt cttcgtcttc tggttctgct ttttcgaata attccattac
    16561 agattctaga ggtaaatctt tcaattccga ccattcgatt ggatcgttta attctgtatc
    16621 aggaaagact gcatcttcag ttgatttatc ctgcatagct gcatctgtat ttgtttcttc
    16681 aattgattct tttatttgct gatcttctgc agttatttga tgaccgcagt ctggacagat
    16741 agtattctgc tccatttttt tcgatccgca atttggacat tttttcatca cttagcgatc
    16801 ggctccttta ctaggtttac gctaccattt aatctatcat attctatacg tcacgccaat
    16861 agcttatttt taggatttac ttaaaaataa tgaatgaatt tccttcctat agaaaaaaaa
    16921 gcttgagact gcgtagtctc aagc
//
LOCUS       DACDAF010000061        16862 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.061, whole genome shotgun sequence.
ACCESSION   DACDAF010000061 DACDAF010000000
VERSION     DACDAF010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16862
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.061"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(38..634)
                     /locus_tag="IVZ69_001876"
     CDS             complement(38..634)
                     /locus_tag="IVZ69_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HAP8183955.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            984..1328
                     /locus_tag="IVZ69_001877"
     CDS             984..1328
                     /locus_tag="IVZ69_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HAP8183956.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVEWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            1329..1748
                     /locus_tag="IVZ69_001878"
     CDS             1329..1748
                     /locus_tag="IVZ69_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HAP8183957.1"
                     /translation="MMTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHTDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1840..2190)
                     /locus_tag="IVZ69_001879"
     CDS             complement(1840..2190)
                     /locus_tag="IVZ69_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8183958.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(2156..3487)
                     /locus_tag="IVZ69_001880"
     CDS             complement(2156..3487)
                     /locus_tag="IVZ69_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HAP8183959.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGVFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSVLSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGILLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLSGIREIFDSSGKLTT
                     DFIANSGIGATLINMGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            3742..4308
                     /locus_tag="IVZ69_001881"
     CDS             3742..4308
                     /locus_tag="IVZ69_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HAP8183960.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            4453..4540
                     /locus_tag="IVZ69_001882"
     tRNA            4453..4540
                     /locus_tag="IVZ69_001882"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4485..4487,aa:Ser,seq:cga)
     gene            4876..5850
                     /locus_tag="IVZ69_001883"
     CDS             4876..5850
                     /locus_tag="IVZ69_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAP8183961.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGEGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNINKEDLDRHELVSYPVIKEQQINYVN"
     gene            6175..8070
                     /gene="asnB"
                     /locus_tag="IVZ69_001884"
     CDS             6175..8070
                     /gene="asnB"
                     /locus_tag="IVZ69_001884"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HAP8183962.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKLDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(8265..8711)
                     /locus_tag="IVZ69_001885"
     CDS             complement(8265..8711)
                     /locus_tag="IVZ69_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HAP8183963.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8939..9088
                     /gene="rpmG"
                     /locus_tag="IVZ69_001886"
     CDS             8939..9088
                     /gene="rpmG"
                     /locus_tag="IVZ69_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HAP8183964.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            9176..9694
                     /locus_tag="IVZ69_001887"
     CDS             9176..9694
                     /locus_tag="IVZ69_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP8183965.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(9771..10727)
                     /locus_tag="IVZ69_001888"
     CDS             complement(9771..10727)
                     /locus_tag="IVZ69_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP8183966.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10893..11699
                     /locus_tag="IVZ69_001889"
     CDS             10893..11699
                     /locus_tag="IVZ69_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8183967.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKITLLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            11696..12685
                     /locus_tag="IVZ69_001890"
     CDS             11696..12685
                     /locus_tag="IVZ69_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP8183968.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            12682..13686
                     /locus_tag="IVZ69_001891"
     CDS             12682..13686
                     /locus_tag="IVZ69_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HAP8183969.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIGLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILPSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13818..14360
                     /locus_tag="IVZ69_001892"
     CDS             13818..14360
                     /locus_tag="IVZ69_001892"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HAP8183970.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            14380..15078
                     /locus_tag="IVZ69_001893"
     CDS             14380..15078
                     /locus_tag="IVZ69_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HAP8183971.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            15099..15311
                     /locus_tag="IVZ69_001894"
     CDS             15099..15311
                     /locus_tag="IVZ69_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HAP8183972.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            15311..16273
                     /locus_tag="IVZ69_001895"
     CDS             15311..16273
                     /locus_tag="IVZ69_001895"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HAP8183973.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRYLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACANLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            16291..16686
                     /locus_tag="IVZ69_001896"
     CDS             16291..16686
                     /locus_tag="IVZ69_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HAP8183974.1"
                     /translation="MVLWVINIILLLIVLAIIFWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
BASE COUNT         5449 a         2852 c         3430 g         5131 t
ORIGIN      
        1 acattgtcaa tcaatgacta attttacaaa ataaatatta tccaagaaga ccacttagat
       61 attgacctcc ataaatcaag gccatactat ataagaaaat cgacagtggt ttagcaatca
      121 aaatgattag tgtatatcgt ttcactgaca tgtttgtcaa tccagccatc aaacataacg
      181 catcgtcagg agcaactgga agaaaaatag ctagagcaaa cagcttctca aaacggtttt
      241 gattatccag ccagccaata tatttgttat atgtcttatc gctaatcatg gaaagtatga
      301 atggctttcc ataacgacgc cctagcagaa aaatgataat cgaaccaatg cagattccaa
      361 tatagttata gataaatcca gcataagggc caaatatcag gacaccagct gcagtactga
      421 tccctccagg aatgattgga ataactactt gcaggatttg gatgaagaca aaaataatcg
      481 gtcctaaaat gatggaatca cctactaatc ctcttaacgc attcaaatct ttgaaaacac
      541 ctaaattaat aaaataaatc gtcagcgcga ttgataggcc taatccgata atggatatga
      601 aatttatcag ttttcgagag gcagcaatat tcattattca tcaactcctt agaggttctt
      661 tgttaactat actttactag aaaagcaact aactgcgcca ttttttgata tgacagaaaa
      721 caaacaattt tgtaagttca tcataagtat aaaagattga tctcaaaaaa acatccaact
      781 aaagacttat ttaataactt gtttttttta aaataaaaaa agcgttagca actatgctta
      841 aaaagcatat cgactgaata aactaagcat tggacaggct gaaagactac atttaaaatg
      901 aaatgcgaag aaacaataga aaataaagtt gccttagaac catagttgaa tcacctaaca
      961 gtcgtgaagg gagaataaga gaaatggcag aaaaacaaac cgcaggacga gatcaattag
     1021 gagattttgc accaaaattt gcagaattaa atgatgatgt tttatttgga caagtatggt
     1081 ccagagaaga attatctgct catcagcgta gtatcatcac catatctgca ttaatttcag
     1141 gaggaaattt tgaacaattg ccagctcatc tgaagattgg caagcaaaat ggcattacta
     1201 gtgaagaaat agcagaaatc attacccatt tagcttttta tgtagaatgg ccaaaagctt
     1261 ggtcagcttt tagtttagca aaagaaatct atttagaaga aaatagcgaa gataagaaag
     1321 aggcgtaaat gatgacaaaa cacgaagaaa tacacaatgg cgtgattttt ccagcaggtg
     1381 aaaaaaacga agcttacgct caagtattta ccgggcaaag ctatctgaat atgttagtga
     1441 atgatcccga agtttctgtt ggtgtaggta atgtaacttt tgaaccaggt tgtcgcaatc
     1501 actggcatgt ccatacagac ggctatcaaa tcttacttgt gaccggagga gaaggctggt
     1561 atcaggaaga aggaaagcca gcaagacgat taatggctgg agatgtcgtc gtaacgcaca
     1621 aagggattaa acattggcat ggtgcgacaa aagacagttg gtttgaacat ttggcgatca
     1681 ctgctggtaa ttcagagttt ttagaacctg taacagatga agtgtatgaa ggattggaaa
     1741 atcaataatg tcaagcttga acagctcctg aaagtagatt ttaatcgaac tttcaggagc
     1801 tgcttttttg attcagtctt ttataaatag aaaatagggt taataatagg aatgagaagc
     1861 acgtcgaaag atcttaatat tgataatcgg ctgggcatac atgatttcca cgtcatcaat
     1921 caaactacct aacagatgat aatcttcccg atcatgtcgg ggattaccta atagttcttg
     1981 atagtagatt tccatactag ggtcccgagg attgttcagc aaatcagcaa gtacatctaa
     2041 atcttctggc tgagtttctg ccgtaccctg tatctctatg aaaagccctt cctcagcaaa
     2101 ttctactcca atacgtattt cagttatttc atgggaatat aaataagtaa gaagctcatc
     2161 gatgattctt tttgataatt ctttttccaa gtgtcttttt ttcctttctg acagcggtaa
     2221 agttatctag tatcggtaca aggatacctg caacgaaacc agttgaaaaa ccactgttat
     2281 atagatttag tcctccgtgc aaagtgctga cgttatggac aagagcaata tgtagcacac
     2341 cagctattac accgtaaaaa ctgccgtaaa aaccgcttat gggcgcaaga cctgtcccaa
     2401 acacagctgc aacaagcatg ccagtactgg tgatctcatg aaaagttcca aacaaagaag
     2461 caataaatat tccgactagt atcggaaaac tgttttttaa atgacaacca aaagcactga
     2521 aacccaccgc agataaaata gcaccgatga caggtccatt taactgaccg ccaaccagca
     2581 aaacataaga agacagcatc agaccaacta agcccatgtt gatcaaagta gcaccaatac
     2641 cagaattagc aatgaaatca gttgtcaatt ttccagatga atcgaaaatt tctcgaatcc
     2701 ccgaaagccg aaaggaatta taatagaaac caattccgac tgtcagcgaa aaaaagccaa
     2761 aaataatcca aatgagagga aagtgatatt cattgaaaac caatgtattt tcgacgattg
     2821 aatagctgaa taacctcaaa acagcagtaa aagtcatcgc aatcaaccca gaggtgaatc
     2881 caatattata aagtgtgaat ccacgatgga aaactaaagt ttgagcagct aagggcggaa
     2941 gaagtatacc aattgctatg ccagctaaat tccccaataa aatacctatc agtaaaggaa
     3001 aacgcatacc aaaagtgata taactaacga ccggtgataa tacgctacca aacagtccga
     3061 tcatgatgta ctgagaaaaa ggtttattga caaatacagc gtatagatac acacctaaaa
     3121 tgattgagat agaattataa aggtttttgc caaaaaaaga gaaaccggta actgttagaa
     3181 tcgaagcaaa taagggaccg tttaaaatca ccttgtgccg ataagctaaa agcacagaaa
     3241 gtaaggtcaa aatccctaca tttatgaatg cgcttccgaa aacacctaaa gcaaaataat
     3301 ctgtcaaaag attgcttggc gaggtaagaa tagttagcaa tccactccaa ttatcagtag
     3361 gagtattaga aagcaagcca ataaaaagaa aaaaaacacc tgtaaaacca agataaaaat
     3421 actttctttt ctgtgaaacg attcgttttt gaggatgaat ataaataacg tcagtttcgt
     3481 tttccattac acaccttctt tttcattttc tttaactata acttgaaatg aaagatttgg
     3541 acaactatca tttaggtcaa aactaaaaat gtaagggaac ccattgaatt taaccaaatt
     3601 tttttaattt tgcaaaaaaa agttaaagaa gactgaaaaa aatttaaaat ataacgtttt
     3661 gagtaaaatg tttgcaaaaa atgctaaaaa tagggtacaa taaaacaaca tatactgcag
     3721 taaagaagtg ggggagtttt aatgagaaga aaagtctata ccaaggatca aattctaaaa
     3781 gctgcttatg atgttgttgc aaaggaaggg tttaaaggat ttactgcgag aaatattgct
     3841 aaaaagatgg ggatttcgac acagccgatt tatctggaat tcaaaaacat ggaagattta
     3901 aaaaatacgt tgctggattc tatctttgaa caactaaaag aagatgtttt ccctattgaa
     3961 cgtactggtg ataaaatcat tgatctcggt ttgaactata tctactttgc aaaaaagcat
     4021 catagtcttt acatggcatt gtacattgat gaacatgggg acggaaagaa aatgcatgat
     4081 ttttcataca attatttccg tgaaatagtt aaagaagatg aaagatacaa tcaattatcg
     4141 gatgaatatg tcgatgctct gcatactggt acatgggtag cagtgactgg cttagcgtca
     4201 ttgatgtcat caaacatcat gcatccaaca gaagaacaaa tcattgcact gatcaaacgg
     4261 acaattgact cgattttagc attagataat cctgaaataa tcagatagtg ttctatcagt
     4321 atgaatttga tcggtaagtc cgttggctgc aaactgtcaa tggacttttt tgctaaaaaa
     4381 agcgatttct gttatttatc tattagaaat aggcttgaca tttcgtgaaa aaagtttaaa
     4441 aatagtactt acggaaggtt ggcagagtgg taatgcaccg gactcgaaat ccggcgaacc
     4501 ggctaatacc ggcgcgcagg ttcaaatcct gtaccttcct tatatcaacg attagaggtt
     4561 gtgaagaagc tgtcctgcat caagtaataa gaacggccaa acaaaaatag cttttcctat
     4621 tttttcgttt ggttgggctt attaccgcag atgcaagctt ttgaacaccg tttgttcgga
     4681 ataaggggct gtgacaagac ttttgtcaca gccccttatt gttgtacttt taacctacaa
     4741 tattttttga ttccccctga gtactatttt ttataaatgc tagtaaatca atcttctttg
     4801 gccttttttt tgataaaaaa aaatactaga tgtaagataa aagtgtaaaa acgatttgtt
     4861 ttaggaggga aaacgatgtg taccgcaatc acttatgcaa cgaaagacca ttattttgga
     4921 aggaattttg attatgagat gtcttataat gaagtagtca ctattactcc aagaaattat
     4981 cgtttcgatt ttagaaaggt aaaaaattta gataaacatt atgcaatgat aggaatagca
     5041 gctggggtat ccaactatcc actctattat gaggctacaa atgaaaaagg gttgagtatg
     5101 gcaggactga attttcctgg caatgctgat tataaagaat tacaagaagg aaaagataac
     5161 gttgcaccat ttgagtttat tccatggata ctagggcaat gctcaaccat agacgaagct
     5221 aaagaattat tggctactat caatctagtc aatatcgatt ttagtgaaaa actacccttg
     5281 tcacctttac actggttatt agctgataaa gaaaaatcga tagtaattga aagtatgaaa
     5341 gatggacttc atttatatga taatcctgtc ggtgtgttga caaataatcc gccatttgat
     5401 tatcaattat ttaatctgaa caattatcgc tcgctatcaa atggaacacc agaaaatcat
     5461 ttttcaaacc agatcagctt gaatgtttat agtcgtggga tgggaggatt gggcttacct
     5521 ggagatctct cttctgtttc tcgatttgta aaagccacat ttactaaaat gaatgctgca
     5581 tcaggtgatt cagaatctga aagtatcagt caattttttc atatactagg ctcagtcgag
     5641 caacaaaaag gagtatgcga tactggagaa ggaaaatacg aatatacgat ttattcttct
     5701 tgctgtaacg ttgataaagg gatttattat tatcgtacgt atgaagacag tcaaattact
     5761 gctgtaaata taaataaaga agacttggat cgtcatgaat tggtcagtta tccagtcata
     5821 aaagagcaac agataaacta tgtcaattaa ttaatgaata gatccgtttg gtatcatatt
     5881 ttctgataca gtcataatta gacacgatct ttaggtcgtg tctttttttg ctgttttttt
     5941 tggaaatagc atccactaat atttttttaa cacgaagaga ataaggtagc ctcaaaaaag
     6001 aaaacatggt aaattagata ttgggacttt attttctgta aaaacagaaa ctttcatctt
     6061 ttgttttcac gtgacgaaat tgtaagagag aaaatattcg tccgctattt attctatgat
     6121 aagatgcata tgaatgaaat aaacagtaat tttatattag gatgtgaaag ttaaatgtgc
     6181 ggtattgtag gttttgttaa cgacaaggac aacaaaaaaa caattattaa tacaatgatg
     6241 gatcgaatcg ttcaccgtgg acctaatagt tcaggagaat atatcgataa acatgttgct
     6301 ttaggattca gaagattaag tattattgac ttagagggcg gtactcagcc tatttacaat
     6361 gaagatcgga caaagatcat tatttttaat ggcgaaatct ataattacca gcctttgaga
     6421 gaagaattga ttgcagctgg ccacgttttt caaacacatg cagatacaga agtccttttg
     6481 catggttacg aagaatgggg aacagaatta ttgcaaaaga tccgcggaat gtttgctttt
     6541 gctatttggg ataatgaaaa gaatgagtta ttcggtgcaa gagaccactt tgggatcaaa
     6601 ccatattatt atgcagaaat gaacggaaca tttatgtttg gttcagaaat caaaagtttt
     6661 ctgcctcatc ctgattttaa caaagaattg aacaaagaag cgttgaaacc ttatatgact
     6721 ttccaatatt ctccattaaa cggcgaaaca ttcttcaaag atgtctatcg tttgcctgaa
     6781 ggccattatt atacgtataa agatggaaaa ctagacattc agcaatattg ggatgcagat
     6841 tttgaaacaa aagaaacgca ttcccgacaa gaatggatcg aaaaaatcga cgaaaccgtt
     6901 caagcttcta ttgaagcaca tacggtcagt gatgtagaag ttggttcttt cttatccagc
     6961 ggggttgatt ccagttatgt aacctctgta ttgaaaccag atcattcttt ctcaatcggg
     7021 tttgatgata aaacctataa tgaagcgatt gaagccagaa aactaaccga actattggac
     7081 ttagataata cagcagcagt gatcgacgga gacatgtcgt tcaaagcatt ccctttgatc
     7141 cagtatcact tagatgaacc tgattcaaat ccttcttgcg tacctttgta ctttttagca
     7201 aatcttgctt cacaaagtgt gcgggtagtc caatctggag aaggggcgga tgaactgttt
     7261 gcgggatacc aaacgtatgg attccatacg aattcaaaat tcatccgtgt gattgctcaa
     7321 ggattgaaaa aattaccaaa aggaacacgc tataatttag gacgtaaaat cggaaaaatg
     7381 aaaaatttcc atggacggat ccatttatat gaatcacttg ctcctgcaaa agaatatttt
     7441 atcggtcatg ctcgagtgtt cgaagaatca gaagcatcag aagtgttaac accaaaatat
     7501 caaacagcac catctgtgga tgaaatcatg actgttcatt acgagaaaac agaaggaatc
     7561 aaagatgaag tcaataagat gcaatatgtc gatcttcatc aatggatgcc aaaagatatc
     7621 ttgttaaagg cagataaact ttctatggca agttctttgg aagtccgagt acctttattg
     7681 gatatcgaag tcatgaaatt ggctcaacaa ataccaagta agtttttatt gaatcaaaac
     7741 aacacaaaag atattttcag acaagctgcg aacaaacatc ttccggaaga atggtcgaat
     7801 cgtgtgaaat taggattccc tgtgccaatc aaagcttggt tgaaagaaga acacggctac
     7861 gaacaagtca aagcattatt cgaagcagat tttgcaaaag aattttttga tcaagaaaaa
     7921 atcatgaagt tgctagatga ccatcacgaa ggacgtaaag aagagcaaag aaaaatctgg
     7981 acaatcttca gtttcttgac atggtataaa gtctactttg tagatgaaac gattccgcaa
     8041 gcagaagcaa tcgactatgt gactgtttga tgaaaatcaa atatcaataa aaaagaggtt
     8101 ttctcctacc gtttaacact gagtgataag aaacaatttc aaaaaacagc tcttcccgtt
     8161 ttatagatat tatgacttat ggttcggagt tggcagagga acaccattgt ttcgaacata
     8221 agggggttgt gacacgattt tcgtcacaac ccctttacat atgttcaata atcgatttct
     8281 ttttcttttg tcccatcttt tttataaatg aacaaagttg attctttgtt ttgtgctact
     8341 tgctttcctt tttcgattgc ttcttttttt gtatcaaaat ggttgcttgc cttttttgcc
     8401 cctttagatt tcacgatcca ttgttcttcc tcatattcta cgatcacatc tgaatcaagc
     8461 agttttccag cacgaggatt cgtatcgtgt tcatccgtct tgcttggatt tttttctttt
     8521 tcgaaagttc gtttttctga ttcactagca tcttcatacc atttttttgc ttgatcaatg
     8581 gcaattggga tcgcacggtt atcagggtac ccttcatcta ataatgcatt tgcgatgtcg
     8641 attgcttttt ttcttgtcaa tttatctaag tttttcattg atgcaggaaa gtccttcatg
     8701 ttccatggca tattagtatc cccctttatt aaaaaacata atctatataa acaagtgtaa
     8761 gggtatttat acaaaaagaa aaagattttg tttgagaagt aaaaccgttg tatttatcgt
     8821 caagtagttt tacttaacaa aatcgtgaaa aacactagca atctagaaaa aatcatggta
     8881 agataatcaa gtctgagagt catcttagag gattcttgta aaaatgggag ggaaaaacat
     8941 gcgcgtaaac atcactttag agtgtacttc ttgtaaagaa cgtaactatc taacaagcaa
     9001 aaacaaacgt aacaatcctg atcgtttgga aaaacaaaaa tattgcccac gcgaacgcaa
     9061 agttactttg caccgtgaaa caaaataatg tttttaaagt tctcaattcc ttgctggtca
     9121 aagaattgag acttttttta tctcaaaaca tctaaaatca taaggagcgg ataatatgtt
     9181 tatttccatg tgggcacaag ataaaaatgg tctgatcggc aaaaatggtt tgttaccatg
     9241 gcgattgcca aatgatatgc gtttctttcg cgaacataca atggatcgaa ttttagtgat
     9301 gggaagaaag acctatgaag gaatggggga tctttcactt ccttatcgcc atatcatcgt
     9361 gttgacaacg caaccaaatt ttcgcacgaa agaaaatgcg gaagtaatgc attcgatcga
     9421 tgaacttttg tcgtatagtc aaacgatctc agaagatatc tatgtttcgg gtggtagtcg
     9481 gatttttcaa gaacttcttc cttacactgg tcggatctgg cgaacattga tcgatagcac
     9541 gtttgaaggc gatacgtata ttgggaatat tgatttttca gacttcgccc ttatagagga
     9601 gtatgagggg ataacggatc aagaaaatct atatgcccat cgttttcaaa aatgggaaag
     9661 agtaaaaaat agggttgctt caaaagaaga ataaaatcta tgcgtctagt ttgttaataa
     9721 gaaaaaaagc atctcacgac taatcgtgaa gattcttttt ttagttaaaa tcaatttagt
     9781 ttttctttga tatcattgac catttcctga ctggcaatag gtccgttata tagccaacta
     9841 gattcaggtc cgaattgcag tacatgattg tctgtcactg ctttaagatt cttccagctt
     9901 ggttcattga acatggcagc atctttgtca ctgttcacaa ggatgatgta gtcagcatct
     9961 aattcagcta gcttttcaga ggaaacagca gaccagtcag aagtggcttt tttggagacc
    10021 tcttccacta gatcaggaac accaaattcc agatcgtcgt atacgattct tccacttgac
    10081 cgatttttgc tgaccataaa ggctgagttg ttggtcaccc acaacactgc agctgtcttg
    10141 ttctcgattt tatctgctag ttcttctcga gttttcttga tggatttttg ataatcggaa
    10201 atgatttttt ctgcctcttt ttcttttgcc aaagctttgc cgacatcttt tagttgttct
    10261 tcccatgtga catctgttcc gttttttaca acataagttg gcgcgatttt gctatattgt
    10321 tcgtatttcc cgccttcgac agtagcggaa gaagaaatca acagcaaatc aggctcaaag
    10381 cttaacactt tctcataagg aaggtcataa gaaatcgttg ggacatcctt taaatcatct
    10441 tgcagataat cttgaatgga accactgcca acagtccact gggcgatagg tttttcccct
    10501 agtgcaatca gatagtcttc taagtaactg ccgatgatcc gtttgggcgc gtttggaatc
    10561 tctactttat gtccaagtgt atctgtgact gtatgagtac tattggatga agtcgtcgaa
    10621 ttggcagttg tagctgtttc tttatctgaa gagggggagc aagcgctcag tactccagcc
    10681 agcagcaata tgctagataa tgtgaatact tttgttttta atttcatttc tttcctccta
    10741 acataattga gaatctttct cattggttat tattcctgat atttcgaacg ctgtcaaccg
    10801 cttcatttgg ctatagatat gaaagtagcg cttgacgaaa tgttgaaaca gcgtcataat
    10861 tgagaatgat tttcagcgaa aggatgggtg aaatgacgag attaagagca gctgacattg
    10921 cagccggcta cgaaaacaaa aaaatcattg aaaacatgtc tgttacgatt cctgaaggga
    10981 aaatcactag tttgattggg ccaaatggaa gtggaaaatc tactttattg aaaagtttta
    11041 cccgtatact acctgtgaaa tcaggaaaga tcattgtcaa taactctgat atctctacat
    11101 acagttcaaa agaacttgca aaaaaaatta cattattagc acaaactagt gaacacccta
    11161 caggtatgac agtagaagaa gtagtatctt acggacgata cccttatcaa aaactgttca
    11221 gtggcatgga cacgcaagat catgaagcaa tcgagtgggc gttggatgct acaggtctag
    11281 ctggatttcg tatgcgggat atcgcaacgc tgtctggtgg acaaacccag cgtgtctgga
    11341 tcgctatggc gcttgctcag gaaacagata tcttgatctt ggatgaaccg acaacatttt
    11401 tagatccggc acaccaatta gagatcctac agttattgac tgaaatcaat caaatgaaac
    11461 aaacaacgat cttgatgtcg attcatgaca ttaatcatgc ttcacgtttt tcagattatt
    11521 tattagcaat gaaaaacggt aagttgatca cagaaggtac acctgaagaa gtgatcacaa
    11581 aagagtgtat gaaaaaaata tttgagattg atgcaacgat tgtcacgctt ccaagaacaa
    11641 ataaaccagt ttttctaacc tatgatttgt tgccaaaaga gcaggaggat caattatgag
    11701 gactatgaag aaaaatagac tcctgctttt ggtctgtttt gttcttttga ttattttttt
    11761 tgttgctctt tcaaatggcg cagcgactgt gggaaaagca gatttttggc aggcgttgtt
    11821 tgattttgat agatcaaaac aaagtcacca aatcatacga aatattcgtt tgcctcgtgt
    11881 ggcgggagca tttcttgtag ggagttgttt tgcattgagc ggtgcattga tgcaaggagt
    11941 gacaagaaat cctttagcag attcaggctt actaggaatc aacgcgggtg cttcgttggc
    12001 aatggccctt agttttgctt tttggcctaa agcttctgat ttttctgtgt ttctaatgtc
    12061 attggcaggt tcttttgctg taactttgct cgtatttggt tttttgcagt tttcgaaaat
    12121 gggcatgaat cctttacagc tgattttagc tggcgtagct attagttctt tttttactgc
    12181 tatcagccaa gcacttaccc aattctttaa tctgcagcag gatcttgctt tttggtttgt
    12241 aggcggagct gccaatatca catggaaaca attagcagta ttgtttcctt tatatatact
    12301 tgctgttttg gtttcttttt cattaggaaa agcaatatct ttgattcatt tgagtgaaac
    12361 acatgcatta gctcttggaa gtcatcctaa acgaacgcgg ttgattgttt tctgtctagt
    12421 tgcagtgtta gcagccattg ccgtttcgtt agtcggacct gtttcattta ttgggctgtt
    12481 ggttccgcca gttgttcgcg gaatggttgg aacggactat cgttatgttc tacctgtctc
    12541 ttttttagtt ggcggtggat tggttatgtt ggcggatttt acagcgagga tgatcaatcc
    12601 cccttttgaa acaccttttg gattagtcat tgcattgatt ggcgttccgt ttttactgat
    12661 acaagtaagg agggaacaac ggtgaaaaaa atatattgga cgttctattt cttgcttttt
    12721 gtacttgtca tcctgtctat aggtagttta atgattggta cgccttttat ttacctggat
    12781 cagctttttg ccacgttcat agggaaagaa tcatcttctt tggcgctgat tgttagagaa
    12841 tttcgagttc ctcgattact gatcagttta ttagcaggag cttgtcttgg cgtttctggt
    12901 tatatcttgc aaggagtaac aagaaatgaa ttggcagatt ctagtatatt gggcattaat
    12961 gccggagcag gatttttagt gatgctttat ttaggtttct tttcgcacta ttcgctgccg
    13021 tttctattgc tagttgtagc ctttctaggt ggtgttttag ctgcttgctg tgtctatctt
    13081 gcggcctatg atcgaaatgg ctttttgggt atgaatcgaa tcttattgtc cggtattgcc
    13141 gttaatgccg gcctttctgc attaacattg ctatgcacga tccaattatc taaggaaaat
    13201 tatggatttg tgaatgcatg gttagcggga tcaatctggg gtgcgagctg gccttatgtt
    13261 tgggcattgc ttccatgggc ggttatctta attccgctag gaggacttta tgcacagagg
    13321 attggattgc tatcatttgg tcaagaacgc gcgcaaggat taggccttaa cgtggctaaa
    13381 agtcaaaaaa tccttttgtt gttagctgtt gctttggcaa gcggtagtgt agcggtgaca
    13441 ggtagtttat cttttgtagg actactagct cctcatgctg cgaagctagt cgtacgtaaa
    13501 gaaaataact ggacctttgt tctgagcggt ttgttcggtt ccatttttct gcttagtgca
    13561 gatatggttg ctagagtgat tctaccaagt ggggaagtac ctacaggaat tttgattgcc
    13621 ctttttggtg cgccatattt tctgtatgca ctttttatca gacaaaaaca cgcgctgaac
    13681 agttgaaatt tattaaaaaa ggaaggccaa tcatttctag gtcttctttt tattctattt
    13741 atgcatttat ttgaaagttc gattgctatt tttctttttt tcctatacca ttttatgaga
    13801 gaaggaaggg tgagtttttg gaccaattga aagtaagatt acgccggaaa ggaatcgaaa
    13861 agctgaaaaa tctggccaaa agtggcaaga aaaaggaaaa agaacagcga atctataaac
    13921 agctattcgc cagcgagtac tggaagtcag caaaagtgat agggacgact ttatcgaatg
    13981 aatttgaact ggatacacag ccggttatcc aacgagcaga aaaagaacaa aagaaaatag
    14041 ttgtacctaa aactttgccg aaacgtcaga tggcgtttta tgaaatggat gaacagtccg
    14101 ttcttgtacg ttcgagtttt ggtgttcttg agccacaatc agagaagctc tatttgccgg
    14161 agatgatcga tctcctcatt gtaccaggta ttatctacaa tagagccggt tatcgaatcg
    14221 gttttggcgg tggttattac gaccggtatt taaataattt tcataaaaaa acatgtagcc
    14281 ttgtttttcg tgaacaattg aatgaacaat ggcaaccgga gagctttgat cagaagatcc
    14341 aacaattgtt tattgactaa aatgaaatgg gaggttttca tgaattatca acagcaaata
    14401 aaattgcgtg catggttaag acgaccgtta tggacctatg cttttttagg gatacagaca
    14461 gcggtcttcc tcatgatgga attatttccg cgacttgaga tcccttatta tgccggaatg
    14521 tatggtcctt atcttgttca cttcaatgaa tggtggcgtt tagtgacacc aatcttcatc
    14581 cattttggac tgatgcattt cgtaatgaac tcactgatac tgtattttat ggggcagcaa
    14641 atcgaggcaa tctatggcca ttggcgtttt ttcttgattt atatgttcag cgggataatg
    14701 ggaaatacag caagctttgc ttttaacgaa gcgaatgttc tgtctggtgg tgcgagtact
    14761 tcgatattcg gtttgttcgg tgcgttgttt atcttagggt ttcattttaa acataaccca
    14821 gcgatccagc agctagtcag acattttctt ttatttattg tgttgacatt tgtttttggt
    14881 cttctggata cctctgtaga tgtttgggga catgtcggtg ggctaattgg cggattagtg
    14941 ttagggaatg ttttgggtct accgaaacaa cagacaagct attcgataca ccaaaggatt
    15001 ctttctacac tagtttttgt atttcttttt gtaatatgta ttttactggg tttaaaaaaa
    15061 tatggtttac ttgtataata tgaaggaagt gcttaaagat ggagagctta tatgatgtac
    15121 agcagctgtt caaaaaattt ggcatcttta tctatgtggg tgcacgcatc tatgacattg
    15181 aattaatgac tatcgaattg cgtaatctgt atgatagccg tttgattgat catgatacat
    15241 acatgacagc gtggcgcata ttaaaaagag agcaccgaat tgaagaaagc cgaaagaaag
    15301 gaaatttgta atggacaaga agattattgg gattgattta ggtggaacaa cagcaaaatt
    15361 tgcaatttta acaccagaag gagagattca acaaaaatgg agcatcgata ccaatatttt
    15421 ggatgatggt aagcatatcg ttcctgaaat cattgaatca atcaaccatc gtttgaattt
    15481 atataatatg aaagccgaag actttatcgg aatcggcatg ggtaccccag gaagcgtgga
    15541 cagcgaagct ggaacggtta ttggtgcgta taacttaaac tggacagaag ttcaatttgt
    15601 gaaaaaactg atcgaggcag gaacaggaat caaattcgct atcgataatg atgcgaatgt
    15661 tgctgcttta ggtgaacgat ggaaaggtgc tggagaaaac gatccagacg ttgtattcgt
    15721 tactctagga acaggtgttg gcggtggtat cgttgctggc ggaaatttga ttcacggcgt
    15781 gagcggagca ggcggagaga tcggccatat cactgtggat cctgaagggt tcgaatgtac
    15841 ttgcggtaaa cgcggatgtt tagaaactgt gtctagcgct actggtgtgg tacgtctagg
    15901 tcgttacttg gcagaagaat acgcaggaga ttcaaaactg aaagcaatgt tagacaacgg
    15961 tgaagaagta acaagtaaag atatctttga aatggctcaa gaagacgatc cgtttgcatt
    16021 gatggttgtt gatcgcgtat gcttctactt aggtttagct tgcgccaact tggggaatac
    16081 attgaatccg tcaagtattg tgttaggtgg aggagtatcg gcagcaggag aatttttacg
    16141 tagccgtgta gagaaatatt ttaaagaatt tactttcccg caagtaagag aatcaacaaa
    16201 aatcaaatta gcagagcttg gtaatgaagc tggtgtcatt ggtgctgcct cattagcctt
    16261 gaaatttgct taaaaaaacg gaggcattac atggttttat gggtaattaa tatcattttg
    16321 ctattgattg tgcttgcaat catcttttgg gaagtctatc tacgagtaat ggccaagcgt
    16381 tcagcaacga ctttgacaga agaagaattt cgagaaggaa tgagaaaagc acaagtaatc
    16441 gatgttcgcg aaaaagatgt gtttgatgct gggcatattt taggtgcaag aaacatccct
    16501 tacactgttt tgaaagattc attaggatct attcgaaaag accagcctgt ctatatttac
    16561 gatcaaaaga aaagcttgag catccgtaca gcaaataaat tacgtaaagc aggttatcaa
    16621 gagatttatt tacttaaggg tggatatgac ggatggtctg gaaaaatcaa aagtaaaaaa
    16681 gtataaaaca gatgattgta tgacagcttt aaaaaccgaa tcaatcatta gattttgacc
    16741 aagatcacat gaacggcgca atggatagtt gtgccgttca ttttttttat tttgtgctat
    16801 tatctacata tataagctaa gcgaaaaggc agaaagaagg aaacaactat gatcaaatta
    16861 aa
//
LOCUS       DACDAF010000062        16778 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.062, whole genome shotgun sequence.
ACCESSION   DACDAF010000062 DACDAF010000000
VERSION     DACDAF010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.062"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(1..312)
                     /locus_tag="IVZ69_001897"
     CDS             complement(1..312)
                     /locus_tag="IVZ69_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP8183975.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(314..511)
                     /locus_tag="IVZ69_001898"
     CDS             complement(314..511)
                     /locus_tag="IVZ69_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterocin"
                     /protein_id="HAP8183976.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(905..2632)
                     /locus_tag="IVZ69_001899"
     CDS             complement(905..2632)
                     /locus_tag="IVZ69_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP8183977.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2625..3818)
                     /locus_tag="IVZ69_001900"
     CDS             complement(2625..3818)
                     /locus_tag="IVZ69_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HAP8183978.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4005..4649)
                     /locus_tag="IVZ69_001901"
     CDS             complement(4005..4649)
                     /locus_tag="IVZ69_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8183979.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4743..4877)
                     /locus_tag="IVZ69_001902"
     CDS             complement(4743..4877)
                     /locus_tag="IVZ69_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HAP8183980.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4879..7011)
                     /gene="feoB"
                     /locus_tag="IVZ69_001903"
     CDS             complement(4879..7011)
                     /gene="feoB"
                     /locus_tag="IVZ69_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HAP8183981.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7008..7481)
                     /locus_tag="IVZ69_001904"
     CDS             complement(7008..7481)
                     /locus_tag="IVZ69_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HAP8183982.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7882..8106
                     /gene="nrdH"
                     /locus_tag="IVZ69_001905"
     CDS             7882..8106
                     /gene="nrdH"
                     /locus_tag="IVZ69_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HAP8183983.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8265..10424
                     /gene="nrdE"
                     /locus_tag="IVZ69_001906"
     CDS             8265..10424
                     /gene="nrdE"
                     /locus_tag="IVZ69_001906"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HAP8183984.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10474..11439
                     /gene="nrdF"
                     /locus_tag="IVZ69_001907"
     CDS             10474..11439
                     /gene="nrdF"
                     /locus_tag="IVZ69_001907"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HAP8183985.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11528..12667)
                     /locus_tag="IVZ69_001908"
     CDS             complement(11528..12667)
                     /locus_tag="IVZ69_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP8183986.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12976..13689)
                     /locus_tag="IVZ69_001909"
     CDS             complement(12976..13689)
                     /locus_tag="IVZ69_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HAP8183987.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13943..14644)
                     /gene="nagB"
                     /locus_tag="IVZ69_001910"
     CDS             complement(13943..14644)
                     /gene="nagB"
                     /locus_tag="IVZ69_001910"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HAP8183988.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14878..16410
                     /locus_tag="IVZ69_001911"
     CDS             14878..16410
                     /locus_tag="IVZ69_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP8183989.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16601..>16778)
                     /locus_tag="IVZ69_001912"
     CDS             complement(16601..>16778)
                     /locus_tag="IVZ69_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8183990.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5210 a         3452 c         2888 g         5228 t
ORIGIN      
        1 ttaaaattga gatttatctc cataatctgc tcgatataaa ccatttattc cagcagttct
       61 tccaatttca ctcaaatttc ttattaattc ctcttgatat tcagtgaatc ttattttatt
      121 agtataagca gtaaaatata gataattcac caatctattt attaaaggac tgggatctaa
      181 ttcatatttt tgtttttcta attttaaata taccttttgt aaaacctcaa gaatatcaga
      241 atatttagga tctttactta tagatatatc attatataat tcatgaacaa tttgcttagc
      301 attttttttc attttagcac ttccctggaa ttgctccacc taaaaaacca cctatagaca
      361 ttcctgcaat acaagtagtt gccttggccc aatcgaccgt acatttattt ttagtgcaat
      421 acactccatt tccataatat tttccactat gagtggtacc cccatagata agttgtgtct
      481 ctttaataga caaaattttt aaatgtttca taatctaatc acccctaaat taatgttttt
      541 agactattat tctaacattc attaaatttc aaaaaacaat tccttcttga aacgtagcaa
      601 aataattcct gaataagaat ttaatcactt ttaagtatat aaactatgta tattctttaa
      661 tattttttga gaatgcactt cgtacataat aaactttaat cacattagtc tttcatacct
      721 acgatcgatc tctttgactc gcacccataa attcataata gtttgtcggc gtctttgaac
      781 gtttcgaaga tgagctacgc attctctttt tttatagaca aaaaagatag agacgaacat
      841 ggagcttcca aatttggata tttgatccaa ttttggaagc tccatttatt tcgtgtctgt
      901 ctttttattt tttccagctt tcgactaatt cttggttctc tttgatccag tcttttgctg
      961 cttgctgtgg atcttttcca ttgttgattt ccaacataac tttttccata tctttttctg
     1021 accaatggaa attgtctaat actttgtaag cttctggctg gtcttctttc aatccttttc
     1081 gaaccatcgt atggatctgc tcttcgcttc ccattccgtt ttcaggatct tctaagtatt
     1141 tcagatcata tttggcaaac atccaatgag gtgtccatcc tgtaactaca attggttcgt
     1201 gttttttgat cgcttgacct agtgcaacgg tcattgctcc tgaagaagat gtctctactt
     1261 tccagtcttt caagttgtca tatttttgga tcgtgttttc agcagccgta actacaccag
     1321 ctcctggctc gattcctatg attttcttac ctgcctgatc ggttaactca tcgatcgaat
     1381 ttacatccat gtaggctggc actgctaaac caacttttgc tcctgtcaaa ttggcaccta
     1441 ggtcttcgac ttgatcttta tattgtgcat attgtgaacc atgagtttta ggtagccaag
     1501 ctgaaaccat ggcatctgac tcgccatttg aaacagattt ccacatgatt gaattatcta
     1561 atggcgtcat cgttacatca tagcccattt gtttcaatac ttcaccgact acatttgttg
     1621 aagcaacttc tgtatcccat tcaacataag ataagttgat acgttttgtt tctttggcag
     1681 atgaaaaact ccctatacca atcgcaccta agatcactac tactacagca ccaatgatca
     1741 gtccttgacg ttttttactt ttctgtgttg ttgctcctgc agctttttta ttgtttggct
     1801 ggttcaaatg ctgtgtaaaa cggtcaatga tgattgctaa gataactaat gcaaccccgt
     1861 tgacaaatcc attcccgact tgtgctcttt gcaatgctga taatacgccg cgtcctaagc
     1921 cgggtgcacc gatcatagag gcaataacga ccattgaaag tgacagcatt gttgtttgat
     1981 tgatccctgc catgatcgta cttttagcta aaggcaattc tagtttgaat agtttttgac
     2041 gacttgtgct cccgaatgaa tcagaagctt ctactaattc tttaggaact tgtcgaatcc
     2101 ctaaattcgt aaaacgaacg gttggtggca gagcaaagat gactgaggca aatacccctg
     2161 gaaccatccc gataccgaaa aatgcaactg ctggaatcaa ataaacgaat cctggcattg
     2221 tctgcataaa gtcaaggatc ggtttgataa tactttgggc tttactgctt tttgccatca
     2281 agatccctaa tggtacccca atgatgatcg agatcacact agataaaaga acaagtgtga
     2341 cagtattcat caaatcattc catagacctt ggttataaat aaaccataga ccgattaatg
     2401 tgaacaacgt aagtcctgga cgtttcttag aaataaagaa agctgctacc gtcaataaca
     2461 agataaacaa aggagctgga atcactaaca gtaaatttgt aatccccgac atcactgcct
     2521 gtccaatcgt ttgtaaaaat gaaaataggc cagaaaaagt tgtcgtaaac cattctgtga
     2581 tattttctac ccagtttgcc actggtaatt gatagttcaa tagattattc atgttcactc
     2641 acctcgcttg tttctgctaa tgcttcaatc acactacctc ggatgacgac accttttaat
     2701 tttccatcct ctacaactgc aagtggagtc ggtgagtcat aaataatatt gaaaatatca
     2761 cttaccacca tgtctttccc aatcaccgtc acattttcat ctaggaagtc gatcaatgga
     2821 cgtttttgct tcctagcttc taacgcttga tctgcagtga tgatcccttt caggtgtctc
     2881 tttctgtcaa cagccatcag catgctgact tcttcattac gcatccttgt caatgcaacg
     2941 tttggtccat cagattcgat attcgtcgtc aatgcaggta ccatgatgtt ttgagccgta
     3001 agcactttgg aacgatcgac ttcttccaca aattcacgta cataatcatt tgctggattg
     3061 gtcaatattt cttcacctgt tccgatctgc atgatttcgc cgtctttcat caaggcgatt
     3121 ctgtccccaa tccgtaaagc ttcattcaaa tcatgggtaa tgaaaataat cgttttttga
     3181 acattggctt gcaggtccag taattcgtct tgcatttctc gccggatcag cggatcaaga
     3241 gccgagaacg cttcgtccat cagcaagatc tcaggatcat ttgctaaagc tctggctagg
     3301 ccaacccgtt gttgcatccc accagataac tgactaggat attggtcttt aaatgaaagc
     3361 aaactagaat tttctaatgc tttttctgct ttttcttgtc gttcttcttt aggtacacca
     3421 cggacttcta acccgtattc tgtattttcc aagatcgttc gatgtggaaa cagaccgaag
     3481 ttttggaaaa ccatattgat tttatgacga cggacttctc gcaattcttc tttgcttaac
     3541 ttcgatacat cttctccatc aatatagata ctgcccgaag ttggctcaat cagacgattc
     3601 aatagacgga tcaatgtgga tttcccactc ccggaaagcc ccatgatcac gaagatttct
     3661 ccttctttta cgtcaaaatt cacgtcatac acaccaaccg ttgcaccggt tttctttaaa
     3721 atctccgttt tcggctggtg atcattcatc atatctaaag cggcttgtgt ctttttacca
     3781 aatatctttg ttaaatgttt tacttctact tttaccaaac aaattctcct tttttatgta
     3841 aattcatttt tctttctgaa aaaagtgacc acactatgtt aacatcatgt agtcactttg
     3901 tcaaaaatga aagaaatttg cttgtccaaa ctgaaaaaaa cttggctaaa tctttgtaaa
     3961 taaaaggttt agccaagtta atattttttt aatatttcac acaatcattc tgcaagctga
     4021 tgctccgggt aaaaaaagtt tgtcatacgc tgtagtgtat attcatttcc aataaaatga
     4081 acgatgtccc ctgccgtaaa tttagcatag gggccaggtg aaacaagcag ttcttcatta
     4141 tgagaaattg cgataactgt ggcgccagtc gcctgccaga tattcaactc gctaattgaa
     4201 cggtccagat gcattgcttt ttctgataaa gataattcaa acggaagtaa aggattcatc
     4261 ttatgtattc gcttcgtttg attgaccagc tgatccaata attgagaaaa atgattcagc
     4321 tcatcttgtt gcttctccac acttgccatg atttctgctt ttgtatcttg gatggattgt
     4381 acatcttgat attgcaatag gaaatctttt gctttttcct tcgaagcaac aaatgcccca
     4441 cttccatgcc gtacttccat gattccaaga tctaccagca cattgatagc cttgcgggta
     4501 gtctcaggag aagcattgta cgtactggca agtgttgagc gggcatggat cttctcaccc
     4561 actttatatc ggttttcaac gatacgttcg gctaaatcaa cagcaatctg ctggtagcgc
     4621 gggcggacga tttttttctt tccagacatt ttctttcctc tttctttttt tactttccct
     4681 catcttacta tgctctagca aaataagcaa aaaaggggag aatagcctct tgcaacgact
     4741 gatcatcgct tgatctgttc cttttttact gggcaagctg tttgacagtc atcacaattc
     4801 ttaccggatt ttaaacgagt atagacaatt gcgcctgcac ttccaaagat taacacactt
     4861 aataagaatg tcgccatcct attcctctcc ttctaatgac aatatagtat aaaactggtt
     4921 cttggatttt ggctgacgga acaaaacata aacgagtcct atcatcagta aaatagcaag
     4981 atacgtccct aacgctacct gtccaccctc caataagtgt cccaactgat aaatcacaaa
     5041 actaactaaa taagctaaac cgcattgata gcctatggcg atccaagtcc atttcttggc
     5101 attcatttcc cgatggatag ccccaattgc cgcaaaacaa ggcgcacaaa gtaaattgaa
     5161 ggctaacaat gaataagctg ctgcgggagt atatgtgtgt tgtagcactt gccagatttc
     5221 tctgccattt tcggatactt ccgcatgacc aaacaaaata ccaaatgtgc caataatatt
     5281 ttctttagcg accaatcctg taatcgctgc gactgttcct tgccagtttc cccaaccaag
     5341 cggctgaaaa acaactgcca ggattcgccc gaaaaaggct aagatacttt ggtcttcaga
     5401 aacaggttga gcataaaaat tataagaaga gctgaaccag atcacgatac tagaaacaaa
     5461 gataatcgtt cctgcttttt taacaaaaga cttgctgcgg tcataggttt gtcttaggac
     5521 cgctgaccat tgaggaaaat gatatgcggg caattccatg ataaaaggag ctgtatctcc
     5581 agcaaacaaa cgtgtttttt tcaagctgat tccagagaaa ataattgcag tcataccaag
     5641 aaaataggca gaaggagcta cccaagattg atgaggaaaa aaggcccctg ctactaaggc
     5701 aataatcggc aactttgcag aacaaggcat gaaggttgtg accatgatcg tcaaacgacg
     5761 atcttgctcg ttttcaatcg tgcgactggc catgacgcct ggcactccac atcctgtagc
     5821 aatcagcata ggaatgaagg attttcctga aagaccgaat ttcctgaaaa gtcgatccat
     5881 gacaaaagcg atcctcgcca tatatccgca gtcttccaga aagctcaagc ataaaaacaa
     5941 tataatcaat tgcggtagaa atcctaacac tgctcccacg cctgcgatga tgccgttcaa
     6001 gatcagctcc tgcatccatc ccgctacttg ccattcagct aacaatctgc caacatgttc
     6061 tggtaaccat gtaccaaaca atgtgtcatt gatccaatct gtccccattg ttcctactgt
     6121 ttgaatagcc agataataga tcagccacat cacaaatgcg aagatcggca aggctaacca
     6181 acgattcgtt gcaatctgat cgattttgtc actcatcgat aattggaaag aatcatttga
     6241 cacaacacag agtgtacata gttgggtaat aaattcataa cgttcattga ccagaatcgt
     6301 ctcactatcg tcgtccaata gtttctctgt taactggatc agttgctcga tctctttttg
     6361 ctgagaaact gctatctcgt aatcctctct taccttctga tctcgttcaa aatatttcat
     6421 tgcataccag cgtttcttgc cgctttgttc tcctagtaca tcttcaattt catgtaaagc
     6481 tgcttctaaa cgtggatcat atgtacaggg aacaggaata gaaggccgct tttttgcaga
     6541 ctcctgaatc ttttcgatta gtttttcgat tccttgcttt ttcaatacgc tgattggtaa
     6601 aactggtaca ccaagaccat aggaaagctt ttctagattg attttttttc cttctttttt
     6661 gatgacatcc atcatattca gaccaatgat cataggaatg tctaaatcca ataactgcgt
     6721 agttaaataa agatttcgtt ctaaattggt agcatcaata atgttgatga tcagttcagg
     6781 ctgttcctga accaaataat ctcttgcaat cacttcttct ggtgtataag gagacaaaga
     6841 atagatgccg ggtaggtcct gaatatgaat gttcggattt tttttcaacg atccttcttt
     6901 tttttctact gttacgcccg gccaattccc tacatattga ttcgaaccag tcaagagatt
     6961 gaacaagcta gttttcccgc tgtttggatt tccgactaac gcgatattca ttctttttcc
     7021 tccctttgta tcaagattag ttcggcctct gactttcgta acgtcagttc ataccctcgc
     7081 actgtcagtt cgattggatc tcccagaggg gctagttttc ggataactat ttttacattt
     7141 cgcgtcaatc ccatatccat taaccgtcgc ttcactgcgc cttgtccgtg gattgctacg
     7201 acgatcccag tctctcctgc ttttaattga tcaagagaag tccagctttc agaggaagca
     7261 gtctttttat tgacaaagat ttgacctagt atttcccgac ttactgccac tcgatgactt
     7321 tttaccagta aaatggcatt gttgcctgat aaattgacga cgacgatttt acttccggca
     7381 acgatcccga tattttgcaa atggcgtttt gttttttctt ctgtttcgat tcgttcgact
     7441 tgataaacga aattctgctt tgcctgcgct aaggtctgca tattgattcc tctcttgtga
     7501 aataaatcat gtattaaaat cattcattat atgttctaat tttcttacgt gttacgcaaa
     7561 taaatgagaa tcattctcac atagaatact ctcggtaatt gagaatgtca attatacttg
     7621 tgatattatg agcgaatctt tagtattgat agataaaaat gagaaaaaaa tatttcttca
     7681 tagttttcca caattttttc tctattaaat ttgctatttt cccacacgat acttgttttc
     7741 agctcttttt tcaaaaacac aaaacttagt attccacagt ttccacaaca caatatgtag
     7801 tgtttgttgt ttgacttttt tactaagagt tttatactat ctattataga taataagaat
     7861 gtgttagagg aggcactcac catgaacgta aaaatctttt ctaaaaataa ttgtatgcaa
     7921 tgtaagatgg tcaaacggtt tttaacagaa aatcaaattg cttttgaaga agtcaatatc
     7981 gatgaacagc ctgaagcagt agactggttg aaagcacaag gattccaaag tgttcctgtc
     8041 attacttctg atgcagaaac agttatcgga ttccgtcctg atcagttgcg taaacttgcc
     8101 agctaacatg actaaaagaa tcaaaacgtg atacatggat ttgaagggct tgagacagca
     8161 ccagtttttg tcgcaaactt ccaaatcctt ttttaaagct taaaaacaat gcaatgattt
     8221 gcaatcaagc atcatcaaat acgaaatgaa ggttgggcgt acgtatgagt cttaaaaatt
     8281 tacaagatgt cagttatttc aagctgaata atgaaatcaa tcggccagtc aatggtcaaa
     8341 tccctttgaa taaggataaa gaagctttag ttgccttttt tgaggaaaat gtcaaaccaa
     8401 atacgatgac ttttccatct attatggaaa aaatcaatta cttgatcgat caagaatata
     8461 tagaagcaga attcattcaa ttgtattcac catcatttat tgaaaagcta tatcaatttt
     8521 tggacgagca acatttttct ttcaaatctt ttatggctgc ttacaaattt tattctcaat
     8581 atgcgttgaa aaccaacgac ggttccgctt atctggaaac ttatgaagat cgagtagcct
     8641 tcaatgcgct ttactttgcg aacggggatg aagaattagc acttgctctt gcagacgaaa
     8701 tgatccatca acgatatcag ccagctacac cttctttctt gaatgctgga cgtaaacgtc
     8761 ggggcgaatt ggtgtcttgt ttcttgactc aagtcactga cgatatgaac tctatcgggc
     8821 gctcaatcaa ctctgctttg caattgtccc gtattggtgg cggcgtaggg attactttat
     8881 caaatcttcg tgaagccggc gctcctatca aaggatatga gggtgctgca agtggtgtcg
     8941 ttccagtcat gaaattattc gaagatagtt tcagctattc taatcaatta ggtcagcgtc
     9001 aaggagctgg cgtggtttat ttgaacgttt tccatccaga cattattgct ttcctttcag
     9061 caaaaaaaga aaatgcagat gaaaagattc gcgtaaaaac tctttctctt ggcgtgatcg
     9121 tacctgataa attttatgaa ttgacacgta aaaacgaaga tatgtattta tttagtccat
     9181 atagtgtcga aaaagaatat ggtgtcccat tctcttatgt aaatattaca gctgagtatg
     9241 atcatctagt tgcaaatcca aacattcgca aacaaaaaat caaagcgcgt gatcttgaaa
     9301 atgaaatctc aaaattacaa caagaatctg gctatcctta cgtaatcaat attgatacag
     9361 cgaaccgcga gaatccaatc gatggcaaga tcatcatgag taatttatgt tcagagattt
     9421 tacaagttca aacgccttct gtgattaacg gcaaacagga atatgaagta ttaggaacag
     9481 atatctcatg taacttaggc tcgacaaata tcgtgaattt gatgcaaagc cctaactttg
     9541 gtcaatctgt gcgtacgatg actcgtgcat tgacatttat tacagatgca tctgatatcg
     9601 atgtcgtacc accgatccaa aacggaaata agctgaatca tacgattgga ttaggtgcca
     9661 tgggcttaca cacttatctt gcaaaagaac aaatggaata tggctcagag gattcattag
     9721 actttacaaa tatttacttc atgctgttga attattggac acttgttgaa agcaacaata
     9781 tcgctcgtga aagaaaacaa gttttccata attttgaaaa atcagcttat gctgacggca
     9841 cttatttcga aaaatacgta actggagaat tccagccaaa atcagaaaaa gtcaaagcat
     9901 tgtttgaagg catttttatc ccaactgctg aagattggaa tgctttgaaa caagcagtaa
     9961 tgaaagatgg actgtatcat caaaatcgct tggcagtagc accaaatggc tcaatttcat
    10021 atatcaacga tacgagtgca agtattcatc ctatcactcg catgatcgaa gaacgccaag
    10081 agaagaaaat cggtaaaatt tattacccag cgccttatct atccaatgag acgattccgt
    10141 attacacttc tgcttatgat atggacatgc gtaaagtaat cgatgtttat gcaacggcac
    10201 aacaacacgt cgatcaaggc atgagtttga ctttattcat gcgttctgaa atcccagaag
    10261 gcatttatga atggaagaca acaacgaagc aaacgacacg tgatttgaat attttaagac
    10321 attacgcttt ccacaaagga atcaaatcca tttattacgt acgtaccttt actgatgatg
    10381 cagaagaaat cggaagcaat caatgtgaaa gctgcgtgat ctaatatcat agatagattc
    10441 gcttattcat attttaatta aaggagcatt ctcatgtcag aaacatatta tgaagcaata
    10501 aactggaatg aaattgaaga tatcattgat aaatccactt gggagaagct gacagagcaa
    10561 ttttggctag atacacgtat cccactttca aatgacctag atgattggcg tacattgtct
    10621 caattggaaa aagatacagt aggacatgta tttggcggtt tgacactgct agatactgtc
    10681 caatctgaaa gtggcatgga tcagttgcgt aaagatgtcc gcactcccca tgaagaagcc
    10741 gttttgaaca atattcaatt catggaatcc gttcatgcca aaagttattc ttctattttt
    10801 agtacactga atacgaaaaa agaaatcgaa gaaatttttg actggacaaa tacgaatcct
    10861 tatctgcaaa aaaaagctga gcgtatcaat gaaatctaca aacacggtac accgctagaa
    10921 aagaaaattg ccagcgtctt tttagaaaca ttcttgttct attcaggttt ttatactcct
    10981 ctttattatt taggaaacaa caaattggct aacgtagcag agatcatcaa actaatcatc
    11041 cgagatgaat ctgtacatgg aacctacatc ggttacaaat tccaattagg attcaacgag
    11101 ttacctgaag cagaacaaga aacgttaaaa gactggatgt acaatcttct ttatgagctt
    11161 tacgaaaacg aagaacgtta tacagaagaa ttatacgatc caatcggctg gacagaagaa
    11221 gtcaagacat tcctacgcta taatgccaac aaagcattga tgaacctagg gatggatcca
    11281 ctctttccag atactgccaa tgatgtcaac ccaatcgtaa tgaacgggat ttcaacaggc
    11341 acaagcaacc atgacttctt ctcacaagtc ggaaacggct atttgttagg tcatgtagaa
    11401 gcgatgaaag acgacgatta tttgattgga ttggaataag gatttatttt aattcaaaaa
    11461 tttttcgaaa aataaaaaga gtttagcgta cagatatttt aaatgtacac tgaactcttt
    11521 tttatgctta ttcacttgtt tcttccagca cttttggact gtctaacttt tccgaaacat
    11581 gttccattct tctcaataaa tagattttcc ggatatttaa tattatcgtc ttaatcactg
    11641 catagacagg tatgcaaatc agcatgccta atattcctgc gacacttcct gctccaatca
    11701 ataccaagat gatcgtcaaa ggatggatat tcattgattt cccaaataac aacggcttga
    11761 tcaaatttcc atctaattgt tggatcacta aaatcgacaa cgccatatac aaagcttgaa
    11821 atggagagat aaacaaaccg acaatgattg ctggtaccgc tccaataaaa gggccgacat
    11881 acgggataat attcgtgatt ccgcaaatga ccgcaagcaa caagctataa ggctgatcga
    11941 atattctcat tgccaaaaag ctcattacac caataatcaa agcatctaag atcgtactgc
    12001 tgatataggc agataatgtt tcgtttaatt cttttaccgt ttggcgtaac tctttacgaa
    12061 tcgctttcgg aaagaagtga gacaacgcat caataaattt gtgcccatcc ttgaacataa
    12121 atagcaaaat aaatggaacg gtaaataaca aaataaaaaa ttgcatcata aatgaaatga
    12181 tttttgagac acttgcagat aaactgacta atatgatatt gaacaaatta ctaagagata
    12241 aatttgctga tgctaattgt tcttccaaat tgaaattttt aaactcttcc cgctgcgcca
    12301 attcatttaa ccatttgctt gtttcatctg catacattgg caagctctgg gtcaattgaa
    12361 ttgtctgttc cattaactga ggcactacat tcatgacagt taaaacaact aaaatgatta
    12421 cgaccaaaaa cgtcaataaa aaaccgaaca ctctcgggat ccgatgcttt tcgagaaaaa
    12481 caacgattgg atcgaacata taatagataa aaccagcaac aagcaatggt aaaaaaattg
    12541 ccgaaagcat tttcaatatt ggactaaaaa tattcggcat ttgtaaaata aagtacacgc
    12601 cgatgatcgt gagtactagc tccactgtcc agaaaaataa ttttgattgt ttaaaacgtg
    12661 attgcataca tctcctccaa ggtcctttga tacttctatt ctatcattta acaaagagtt
    12721 acgcgctgag attttcattt gcttaaaaaa aacaaaaaaa ataaacatat tttaatgagt
    12781 agacgagtac ttaaacaaaa acacggtttg gagtagtgac aaaaattata ctgcagtccc
    12841 tttttccaaa taaacggtgt tcaaaagctt gcatcttcgt aataagccca gccaaacgaa
    12901 aaatataagg aactattttt atttggctgg gcttattact tgatgtagga catctatttt
    12961 acaacctcag atcatttatt gcgcaatact gactaaatgc aactttgtga tatttttgtg
    13021 tacggacaac tcctcgatca catcggcata agtgagccct tttggaagat caatcgtata
    13081 gatatttttg tacactcggt agtcatcaac gaattttacg tcaaaattca catcttcgat
    13141 tacgatattt ttctcttcaa aataatcggt aagaaaatct ttggtttctt ttctatggat
    13201 aaattggatt tctaactttt tagtcgtagg tacatggatc acgcgtttca ctactgtgag
    13261 tgcaatagca atcccgataa aactgatgat cgcaatggaa tagtaaccca tgccgatggc
    13321 gatccctaat ccagcaattg cccataaaga agcggcagtc gtaagtcccg tcaccgattg
    13381 tttcgtgacg atgatcgttc ccgcgcctaa gaaaccgaca ccactcacca cttgagcaat
    13441 cagccttgct tcatctgaac gaatcgttcc agcaagctgt ggatactcta aagcatctct
    13501 taatgcacca ctagcgatct caacttggat caatgcaatg atacatgctc ccatacaaac
    13561 taaaatatgc gtacgcatac ctgctggacg atttttatat tgtcgttcaa aaccgattgc
    13621 tccgccaaat agcatagcga tccctaaacg taaaataatc tctggaattg tcaataccat
    13681 atcattcatc taaacaccct ccagtccaat atatcatgtc tgaaaggagc agacaaaaaa
    13741 agtgcaattt ttacctctta cgaaaaaagg actgtgacaa aatttttgtc atagtccttt
    13801 ttatgaataa acggtgttca atcagctgac cctcggtatt actcaacaaa cggcaaaata
    13861 tggggagcta tttttccttt gtcttctcta atactcaggt caaaacgctg atttcacaac
    13921 ctctttagcc tactattgaa aattacaact tacttgctgc ttcttcatcg atgatcacaa
    13981 caacattgtc gtgattttgc aatacacttg ctggcaaatg attcgttaca ggtccttcaa
    14041 tcatcccttt gattgcatca gctttgcttt cgccaaatgc catcaagacg atttctttac
    14101 ttttcataat tgaaccgatt cccattgaaa cagcttttgt tggtacatct tctgctttat
    14161 cgaagaatcg tttgtttgca ttgattgttg attctgttaa gtcaactact gaagtcgttc
    14221 cgtcaaatga agcaccaggt tcattgaaac cgatatgtcc attttgcccg attcctaaga
    14281 tttggatatc gattggatgt gcatcgatga tttgatcata ctttttgcat gctgcttcca
    14341 gatcttctgc ttttccatct ggtacaaacg tttctttgaa tggtttttta tcaaataatt
    14401 ggacatccat gaaatgacgg tagctttgtt catctgaacc gcctagtcca acgtactcat
    14461 ctaagtttac agaagtcatt tcactgaaat ccaaatcgct tgaagtcatt tctttatata
    14521 aagtaactgg tgtgcttcct gttgccaatc ctaatacttt tgcacctttg ttcatacctt
    14581 ctttgatgat ttcaaatgct ttttttccgc cttcttcagc gttttttaca cgaatgattt
    14641 ccatagtgat tgctccttta tattttggta tagcccaatt atagcattct ttttttcttt
    14701 ttacaataat tagtatagac caaattgcat ttttttcatt ttcttgacaa taaataggaa
    14761 tccgtgttag gtttcataag atggttcaat caaacaatcc atgttgcatg aaaaccaagc
    14821 aagtgattca ctgtggacgc tttatgtctg cagttttttt atgaaaaagg agttattatg
    14881 agtatactga cattaaacaa cattacccag caatttggcg acaaaatcct ctatgaaggt
    14941 gtcgatctgc aattaaatgc tggcgaacat cttgggctga ttggacaaaa cggagccggt
    15001 aaaagtacat tgattaaaat catcactggt gagatcttac cagatgacgg acagatccat
    15061 tggcaaaaaa atattcacaa aggttacctc gatcaatatg tggaagtcga tgaaacatta
    15121 acaatcgaag aatttctaaa aactgcgtac gcaaaagaat acgaaaagga agaaaaaatt
    15181 gcttttcttt accaaacata tagcgagacc ttcgatgatt ccttgctgga aaaagctggg
    15241 aaactccaaa cggaattaga ccaaggagtg ttttatcaaa tcgacacctt agttgctgag
    15301 atgagcagcg ggttggggat cgatgtctta ggtttagatt cactgttgaa aaatctaagt
    15361 ggtggacaac gttcaaaggt gattttagca aaactacttt tagaaaaccc agatgttctg
    15421 atcttagatg aaccaaccaa tcacttagat gatcagcata tccaatggct gacgcagttt
    15481 cttcaggatt ttgacggtgc gtatatcgtg atttcccatg accaagaatt tcttgatcag
    15541 atcaccaccc atatcgcaga catcgagttt ggaaagatta ctaagtatac tggccatcta
    15601 aaacaagcat tgaaacaaaa ggaacaaaat cgcgaaagct atttgcgcca atatcatgct
    15661 caacaaaaac aaatcgaaaa gaccgaagct tatattcgaa aatacaaagc cggttcccga
    15721 tcaacgatgg caaaaagccg acaaaaacaa ttagataaaa tcgaacggct gacgcctcca
    15781 gcttcagcaa gtaaagctgt ctttgatttt ccattctcgc ctattgtcac gacattagca
    15841 gtggaaacaa ctgatttagt catcggatat gatcgaccgc tacttgcacc catcaatttg
    15901 accatccgct ttggtgaaaa tattgccatt cgaggcttca acgggattgg aaaatctact
    15961 ttattaaaaa cactgatcgg tgagattgaa aaaataagtg gcgatttcca cttcccagat
    16021 aacacaaaaa tcaattactt ttcacaagat ctgtactggg aaaatccatt agaaacacca
    16081 ctacaatatt taagcagtca atttccaaaa gcgactatca aagaattacg tcgccaacta
    16141 gctaaagcag ggttagttaa tcaattagca agtgaacctc tcactacatt aagtggtggg
    16201 gaacaaacta aggtgaaact tgcacagttg acaatgaacc aaggtaattt actgattctc
    16261 gatgaaccga cgaaccatat cgatcaagaa acgaaagaaa gcttacaaga cgggatacag
    16321 aaatttccag gaacagtaat catcgtctct catgaacaag aattttatca agatcttgtg
    16381 caacgagtca ttgagattga accaaaataa acgtttgatt gaatagttga aaaaaaggag
    16441 ctgtgacaaa agttttgtca caactccttc ttctgaataa atggtggcca attagctgac
    16501 cttcggtatt agctcaaaaa acggcaaaat atgaggagct atttttattt ggctattctt
    16561 attacttgat gcagaacagc ttttcacaac ctcttttcgt ctatttttta ttttcgagat
    16621 ttctctttcc tttaaaaaca actgtttgaa agaagaacgc acatccttga aaaacaagcc
    16681 cgctaaccgt tacacctaac cagccatact gctgccacat tgtcgtccct agcaatgaac
    16741 cagccgcacc tccaataaag tacataaaca taaataca
//
LOCUS       DACDAF010000063        16748 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.063, whole genome shotgun sequence.
ACCESSION   DACDAF010000063 DACDAF010000000
VERSION     DACDAF010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16748)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16748)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16748
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.063"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..658
                     /gene="scm"
                     /locus_tag="IVZ69_001913"
     CDS             <1..658
                     /gene="scm"
                     /locus_tag="IVZ69_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HAP8183991.1"
                     /translation="TSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTD
                     TSASSDSTDTTSTTSDSTDTSASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSSDS
                     STTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSD
                     NRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR
                     "
     gene            complement(813..1799)
                     /locus_tag="IVZ69_001914"
     CDS             complement(813..1799)
                     /locus_tag="IVZ69_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HAP8183992.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(1822..2388)
                     /locus_tag="IVZ69_001915"
     CDS             complement(1822..2388)
                     /locus_tag="IVZ69_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HAP8183993.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            complement(2402..2818)
                     /locus_tag="IVZ69_001916"
     CDS             complement(2402..2818)
                     /locus_tag="IVZ69_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HAP8183994.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(3275..5209)
                     /locus_tag="IVZ69_001917"
     CDS             complement(3275..5209)
                     /locus_tag="IVZ69_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP8183995.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5511..6446
                     /locus_tag="IVZ69_001918"
     CDS             5511..6446
                     /locus_tag="IVZ69_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HAP8183996.1"
                     /translation="MKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSESSTAQSST
                     AKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKYDNVNENG
                     ESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSSESFQNYA
                     QQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGKVTESNFD
                     YIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPANVEVVTGA
                     THSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            6536..7639
                     /locus_tag="IVZ69_001919"
     CDS             6536..7639
                     /locus_tag="IVZ69_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAP8183997.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            7652..8605
                     /gene="menA"
                     /locus_tag="IVZ69_001920"
     CDS             7652..8605
                     /gene="menA"
                     /locus_tag="IVZ69_001920"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HAP8183998.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(9540..10886)
                     /gene="gor"
                     /locus_tag="IVZ69_001921"
     CDS             complement(9540..10886)
                     /gene="gor"
                     /locus_tag="IVZ69_001921"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HAP8183999.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(11020..12261)
                     /locus_tag="IVZ69_001922"
     CDS             complement(11020..12261)
                     /locus_tag="IVZ69_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP8184000.1"
                     /translation="MTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAYGLRS
                     RAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISAVIVS
                     DPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVAEIRK
                     NTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFGQERN
                     SLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNVYKAA
                     VDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVYKFVG
                     EVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRAPNPM
                     MILTMPVAQPVKPGDMIRKRK"
     gene            complement(12279..13202)
                     /locus_tag="IVZ69_001923"
     CDS             complement(12279..13202)
                     /locus_tag="IVZ69_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HAP8184001.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(13423..15915)
                     /locus_tag="IVZ69_001924"
     CDS             complement(13423..15915)
                     /locus_tag="IVZ69_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HAP8184002.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(15922..16389)
                     /locus_tag="IVZ69_001925"
     CDS             complement(15922..16389)
                     /locus_tag="IVZ69_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HAP8184003.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(16525..16598)
                     /locus_tag="IVZ69_001926"
     tRNA            complement(16525..16598)
                     /locus_tag="IVZ69_001926"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16562..16564),aa:Arg,seq:acg)
     gene            complement(16656..16729)
                     /locus_tag="IVZ69_001927"
     tRNA            complement(16656..16729)
                     /locus_tag="IVZ69_001927"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16693..16695),aa:Pro,seq:tgg)
BASE COUNT         4953 a         3514 c         2984 g         5297 t
ORIGIN      
        1 cacaagtgat agcacggaca catcagcttc aagtgacagt acagatacta cctctaccac
       61 aagtgacagc acggacacgt cagcttcaag cgacagtaca gatactacct ctaccacaag
      121 tgatagcacg gacacatcag cttcaagtga cagtacagat actacctcta ccacaagtga
      181 tagcacggac acgtcagctt caagcgacag tacggataca tctaccacaa caagtgatag
      241 cacggacacg tcagcttcaa gtgacagtac agatactacc tctaccacaa gtgatagctc
      301 agattcatct accactacaa gtgatagcac ggacacgtca gcttcaagtg acagtacaga
      361 tacatcctct accacaagtg atagctcaga ttcatcaact tcaagcgata gtacagacac
      421 gtcgtctacc acaagcgata cacgtcatgc aagtgtctcc ttctcaaaaa caagttcgga
      481 taacaggacg aactttaact taactaataa aacaagcaat gacaatggaa acaaatcaaa
      541 aagagcactt cctaaaactg gaagtcaatc gaataattgg ataacactcg caggcgttat
      601 attacttgta atcggtttaa gaatcacttt tatgagttat aagaaatcga aaaggtaaaa
      661 aaatattcaa gataaaaaag agcaacgtcg ctaacggacg ttgctcttta tttttgcttt
      721 ttatcataaa tacaagaact acaattcaat ttgtcaaaaa acacgtagat ttccttctga
      781 gaaatttatt tacgtatcga acctttccct attcagtctt tgcgatccaa aatcagttgg
      841 gtaagggaaa agagattctc ttttgttcga agagaggtgg caggtaattt ctttatttcc
      901 ttcaaagcct tttctgtgta agaggccgct aacttcctag cttcttccac gcctcctgta
      961 tgttcaacga ttttgcgtac ggcgtcgaca tcttcttctg tcattgccgc tttcttctct
     1021 aaataaggta gtagctttgg tttgtttttt tgcaaagagt agatcaacgg taaagaatag
     1081 accccttgac gcatgtcttc tagtacaggt ttgccgattt cctggctctc ttttgtataa
     1141 tctaaaatat catcgataat ctgaaaggcc atcccgatag aaagtccgat atctcctgct
     1201 ttttttgcga agcgctcgct tgttccactt tcaaaagcgc caacagaaca acttaattgg
     1261 aacagttcag ctgtcttacc tgaaatattt tccaaatatt cttttacaga aagttcataa
     1321 ttatagcgat catccatctg ccctaattcg ccattcaata ctttttccat actgcgagaa
     1381 ttcaattgga gacttttcaa ggaagtggag taatcagaca atagtttaaa acagcagaca
     1441 aataaatagt ctcctgcata gacagaaacg acattaccaa actgactacg gatattaggc
     1501 tgaccacgtc gcagatccgc ttcatcaacg atatcatcat ggatcagtgt ggccgtatgg
     1561 agcatttcga tagaagctgc caaagcgatg gctttgtctc gatcttgctc tggtccaaat
     1621 tgtgagaaca atagctgata ggcaggacgc aacagctttc cgccggcatg gatcgtttct
     1681 ttgatggctt gttcgacagg tttgtttttc aggcggacag tttcttccat ccgttttagt
     1741 gtttctgtca attctttact taaagcagga tagttttccc acattggatg tagcttcata
     1801 aaaaaactcc ttgtgtgacg attatttttt ggtaaacatt gggctccatt tttgtttggt
     1861 tccctgctca taatcttttt ggaatcgttg aagtgtctgc acatgtcgta aaagataatt
     1921 cgctgcgatc ccgattgcaa tccctgataa aatccctaaa actgaaagga ctggcaagta
     1981 caacatgact gtccatgatt gtgcaatgaa agaagccatc aaaagctgtc cgacattatg
     2041 catgaaaccg ccggccgcac taattccgat gatactgaca cgttttggtc ctaattgctt
     2101 gaccaataac attccaaaat aactaagcaa agcaccactc atactataaa ggaatgtgga
     2161 aatcgttccg cctagcaaag tagtcaggaa tagtcgtagc caaagtagta agaagctgtc
     2221 ttgttttttc atggtaaaaa tggcaacgat cgtgattaga ttggctaagc ctagttttgc
     2281 accaggcgca aaagaaaaag gataagggat catattttcc aataaaccaa tgatcactcc
     2341 ttgtgcaaca agtagcgaaa tataaatcat tttttgtaat ttactcatgg tgtgtgaagg
     2401 tctaataaat cagactgtct tcgtcacctc catctgttga acggacttcg atcactaatt
     2461 tatgtggcaa acagacgatg gtttcgccat ttttcgttgc ccagcctcga cgtacgcaga
     2521 tctggtcatc gcaatctgct tcttttatcc gtactcgatc gccatctatc tcgatcaagt
     2581 tataatctcc gtgttcatct ttgtaagtat atgtgttgct ctcttctcca gccatcaaag
     2641 ggaatgtttt gatttctgtg ccatccacac gcagtaccgc ttctttttct gctgttgcgg
     2701 tgttttgctg aagaccaaaa atcatgactg gtaaaaaaga aagaacagtc aaaagcaaaa
     2761 taataaaaac atcccaaggt ttgagcagac ttttttcagc aaattcttta aggctcattt
     2821 ttgttctcct ttttccagat taactcaccc aattttagca taaaaacaag aggttgtgac
     2881 acctgtgtct tgctttgagt aataagaacg aagaatagaa aacagctttc catgttttct
     2941 aattctttgg gcttattacc gagaagcagc aggtggaaca ccgtttataa caagaggttg
     3001 tgacagaagt gggcaacttc aagaaataag aaggaattta cgaaaattac ttttcaagtt
     3061 tttgtgaaat ttcggcttat ttttcgaaga agctacttct ggaacaccgt ttataacaag
     3121 aggttgtaac agaggttgtg acacctgtgt cttgctcatg gaggcttatc tcgggcatct
     3181 tattccttta attttacata aaaaggaggc tgtgacggtt tgtctcagcc cctttctatt
     3241 gaaatcttgc attcaaataa cgttctttat ctatttattt cttgccgtac tgggaacttg
     3301 gtctaccgta ccaccaatta cctagtgtac gttgtagcca tggaattacc cagcgatcca
     3361 acccaatcgc acgtccggaa ccgttcatca atgcgaaagc aacaaaaatg aaccaaatgt
     3421 ttacccagta aaacatgcct gataagcaga acgtgatcac caatacaatc gttgtcgcac
     3481 tgcatagcca tgtgaataat ccagcaatca atgctaatgc caaggcaatt tcaaagaata
     3541 ccatgaattt ttggaagaac attgctacat cattgtttgg catgatcact tgcatgatct
     3601 ttgtgaacca gtctggtgac ttctcaatca cagccattgg ttcttcaccg tatgcataac
     3661 tcaaaccaaa atgtgcagct tgagtcgctg cttctccggc acttgcccct gctccgctgg
     3721 cagctgtggt tgcatcacca gcagcagaag caccactggc aacatctgtt acattgtatt
     3781 cccatgtcca agggaacaca ctgtttccag tgaaccatga tccttcacca aaccaagtac
     3841 ttggtttgaa cacttcacca ttcccaatga tttttttgga agcttcaacg aaccaaacta
     3901 aaccatagaa aatacgaagt ggcacactcc ataagacatt gccgtaacga gaagaatgtc
     3961 ctcgagtcac gttgcgatca tctttgatat ggaaaaactc atgcattaaa tattggaaca
     4021 tataataacc agaacgaata tcaaagaagt atttcaaatt cacgatatgt ttcattacga
     4081 tagctaaaaa tccgcttaaa tggatcttat caaataggtt agctaccccc catttggcac
     4141 caatagaaac cataaatcct tgatagtttc ctttaaattt atgcttttct ccgcctttga
     4201 tcgaagccac gatattcgct gcggctgtgt gtcctgtttg ttcagcagct tgaacgatct
     4261 gcggtgtcgg tgttcctggg aattcttcat aaaagactaa atcaccaatg atatagatgt
     4321 ttttatcttc gtagcctttt gcctgcatat attcattggc gatcaaccgc tgtccgcgtg
     4381 ctgattctaa tccaaagtca gcagcgtcag aagttccttt gacaccagct gtccaaatca
     4441 gtgtgtgagt cggaatgttg cgtccgtctt tcaatttgat atgatcagca gccacttcta
     4501 cgattggtgc attcaataat aattccacgt tgtgcttacg caaatagcgt tcagcttttg
     4561 cagcatcatt tcgatccaac atattcaaga tcgtcggcat tgcctctacg accatcagtg
     4621 tgatttcgtt tggatctaat ttataatctt tggctaggcg atttttccag tcgatcagtt
     4681 ccccaatcat ttcaataccg gtaaatccag aaccacagac aacgaaagtc agcatggctt
     4741 tacgcagttc atcatctggt tccaatgcag cttttgctac tgtcttctca atatgttccc
     4801 gaatccttac agaatcttca aatgaccaaa gggtgaatcc gtgtgctttg acaccaggtg
     4861 taccaaagtc attcggctct ccgcccattc caaggatcag ctgatcaaaa ggataggaac
     4921 ctaatttggt cttgacgatt tttcgttctt tatcgatacc gattacagtg tctgtgacaa
     4981 gttgtacatt cttttgacga gcaaacaaat gctgcagatc gtattggatt gcttctggtt
     5041 ctacacgtcc gccagctact tcatgcaact cggtcatcat agtatggtac gaatgacgat
     5101 cgatcagagt aattgctaca tcttcttttt tcagtttctt tgccaagtat tttgtagctg
     5161 aaacaccggc atatcctgct cctacaacga caatattttg ctttgccatt gatcatccgc
     5221 tccttataga ctatctatat aatgaatata tgataattct tttagtttga tacttattac
     5281 acaatctcca tatattatat agatgttctg ttcttttgtc taactccttt tggatttttt
     5341 tcaaatttta aaataaagcg ttttttcacg aaatttgctg aaagaaaacg tttgaaatat
     5401 tacatgggtt atttatcaaa aatagttgac ttataggcta aaaagattag aatgtataat
     5461 gaatcacaaa gaaaaattgt ggactagaaa tggaatggtg gggtattaaa atgaagaaaa
     5521 aacgttttgt aactggattt gccgtattag cattttcagc tctagtgtta ggcgcttgcg
     5581 gcgcagatga caacggaagc tcaaactctt cttctgaatc atctacagca caatcttcga
     5641 ctgcaaaaag cacaacagaa tcatctgcaa aagttgtagc tggcggagat ttgcaagacg
     5701 gcacatataa attagaagaa aaaaattatt caaatggtta ccgtgcagtc tttgaaatgg
     5761 ttgtaaaaga cggcaaaatc actgaatcaa aatatgataa cgtcaatgaa aacggcgaat
     5821 caaaaacaaa agatgcagaa tacaacaaaa acatggaagc aaaatctggc acaaacccag
     5881 aaaaatacat tcctgagttg aatgaccaat tcttaaaagc acaaagcgca agcggtgtgg
     5941 aagtcgtaac tggagctact cactcatctg aaagcttcca aaactacgca caacaattga
     6001 tccaagctgc tcaagctggt aacacagata caatcgaaat cgacaatggt gctgatttga
     6061 aagacggcac ttacaagctt gaagaaaaga actactctaa cggctaccgt gtgcaattcg
     6121 aaatgacagt tgctggcggc aaagtaactg aatcaaactt tgattatatc gacaaagacg
     6181 gtaaatcaaa acaagatgat acagaatata atgaaaatat gaaagcaaaa agcggtacag
     6241 aaccaaaaac ttacatccct actctgaacg acgaattcgt caaagcaatg ggcgaagaag
     6301 atggctcacc tgctaatgta gaagttgtta caggtgctac acacagctca cattcattca
     6361 tcatgtacgc acaacaatta gtgaatgcag ctgaaaaagg cgacactcaa acaatcgaag
     6421 tagataatat cgtaacagaa aaataatcac ataatcatac taataaaagt tggagggtgg
     6481 gacgatagcc agattaggca gtcgtctcac ctttcaaaat gaagagagga aaaagatgcg
     6541 gaaaaaacta ctattttcct taatcacact gggcatctct tttatggtgc taactggctg
     6601 cagcaactca gcaaataaaa caaccactga aagttcagca gctaccaaga tattgaaaga
     6661 tccatattct gatgaacagt tcttgttagg gacttacgtt cgtatccgtg tgtatgatga
     6721 aggcaaagaa tcagcattga aacctgcctt cgatcgagta aaagaacttg gtgataaaat
     6781 cacgatcaat caaaaaggtt ctgagatcga tgaagtgaat gagcaagctg ggatcaaacc
     6841 agtaaaagtt tctgatgacg tctacacgtt agtcaagcgg gcctacgaat atagccaaga
     6901 ttctcaaggc ggattcgata tggcgattgg tgcaatcaca caattatggc gaatcggttt
     6961 tgatgacgcc agaaaacctt cccaagaaga aatcgatcag gcattgaaat tagtggatta
     7021 tcataagatc gaactaaatg acaaagaaaa aactgtttat ctaaaagaaa aaggaatgat
     7081 catcgattta ggtgcaatcg ccaaaggtta cattacggac gaagtagtga aagtcttgaa
     7141 aaaacaagga gtgaccactg ccatcgttga cttgggcggt aatgtctatg tcttaggcca
     7201 cagcccaaga ggcgaaaacc aagactggac agtcggcatc caagatccga acatggctcg
     7261 cggatctgtt ttaggttcta ttaaagaacg gaacaaaaca ttagttacct ctggaattta
     7321 cgagcgttat ttagaagtag atggcaaaaa ataccatcat ttgtttgatc caaaaacggg
     7381 ttatccgttc gacaatgata tcgcaagtgt cacgatcata acagataaat caattgatgg
     7441 tgacgggttg tctacagcag tcttttcaat gggtgtgaaa aaaggactgg aatacgtcga
     7501 aagcgaattg aataacggga cggaagcgat cttcgtgaca aaagacgata aagtatatgt
     7561 gaccgatcca atcaaagaca ccttcaaatt atcggaggac tcccattaca cgatgggtga
     7621 ccgttctgaa ctaaaataag gagtacgaac catgacacta aaaatctttt tagaagtagt
     7681 tgaaatacga acaaaggtgg ctagtgtatt tccttttgcg gtaggggtat tattctctat
     7741 cgcttttttt catgagatac attggctaaa cactttttta ttttttattg gaatgctagt
     7801 ttttgattta gcgactaccg ctatcaataa ttacatggat tatgaaaagg ctcattctga
     7861 agtatataag tatgaagaaa atgtcattgg ccgcagaaat ctatctcctg tattgattcg
     7921 aaacatgatt ttagctatga ttgcatttgt ttttgttatc ggcgttattc taacgatcaa
     7981 tacgggttgg cttttacttt tgatgggatt tatctgttgt tttattggag tattctatac
     8041 attcggaccg attcctttat ctcgaatgcc tttaggggaa attttcagtg gggtgactat
     8101 gggccttgga atttttgcca tggtcgttta tgtcaataca ttcggttcag atgtctatga
     8161 tctgacagtc aacttttcat ctggacaatt tgatttggta ggaaatcttt gggctatagc
     8221 agcaatcgta ttagcttcct tacccttggt gtttacgatt gccaatatca tgttggctaa
     8281 taatttgcgg gatcttgacc gtgatattga aaatcatcgc tatacactag ttttttatat
     8341 cggacgtcct gcgggaacag tcttattcca gctattgatg tatgcttgct atttcgtgat
     8401 tttaatgggg ttgttgagcg gtatctatga atggccgatc ttggtcacct tcttgacctt
     8461 gccaattgtg aagaagcatt tggatcaatt caagcaaacg ttaccccagc ctatcagttt
     8521 cagctattcc atcaaaaata tggtcttatt caatgccagt tatgtattgg ggctattact
     8581 aacaatcatt atgcaagcca tttaacagca tgaagaggtt gtgaaaaaac tgccctgcat
     8641 caagtaataa gaacagccaa ataaaaatag ctccttatat ttttcgtttg gttgggctta
     8701 ttaccgcaga tgcaagcttt tgaacaccgt ttatcaggag gttgtgaaaa agtcgcttag
     8761 tttcgagtat taagaaaaat tttgtgaaaa tggctttcca catttttgca taaatttggc
     8821 ttaataccga gaaactggct tttgaacacc gtttatcaga ggttgtgaaa aagtcgctta
     8881 gtttcgagta ttaagaaaaa ttttgtgaaa atggctttcc acatttttgc ataaatttgg
     8941 cttaataccg agaaactggc ttttgaacac cgtttatcag aggttgtaaa atcagtgttt
     9001 tgtcctgagt attagagaaa caaatggaaa aatagttcct catattttgc cgttttttga
     9061 gctaataccg aaggacagct gattgaacac tatttgttcg gaaaaagtga ctaactatga
     9121 cacaattttt ttcacagtcc cttttttcac ttgatttgat tcgtaccagc gaacttgacg
     9181 agaactttct tggtttggta actatatggt attcttttaa catcctcgtt tgcttcttct
     9241 aatttattta tacaaagtca cactttttta aacatctgtt cttcgataca tttctatttc
     9301 ttttaaacat cgataccaat attttgaact taagagtgca taccaaatgg attcatttac
     9361 tcttcgtcag ttacgaagat aatcaaaatc tccaacttcc ctacttattt cgttttgaga
     9421 attatcgaag caatcttaca taaataacta aaaaacaaaa aaccagaaaa tcagtatact
     9481 gattttctgg ttttacatgg tttgttcaat aaaaagctgt tggaactgtt aatattaaat
     9541 tatcgcatcg ttacgaattc ttccgctcct gttggatgga tggctactgt attgtcaaag
     9601 tcttctttag ttgcacccat cttgatagcc acggcaaaac cttgcagcat ctcatcgaca
     9661 ccaacaccaa tagcatgtaa gccgacgatt ctttcttctt ttccgacaca gatcaatttc
     9721 atttcgcatt tttggcgata atcatttaat gcaaagtaca ttggggtaaa gcgtgaacga
     9781 taaactttca attcattttc gccatatttt tccaatgctt cttcttctgt caaaccaatt
     9841 gttgcaattg gtggatgcgt aaagacgact gtcggaacaa gtttatagtc aagataagaa
     9901 tctttctttc cattaaataa acgttctgat aaacgtctac cagctgcgat tgcaacagga
     9961 gtcagatcta atttaccgat cacatcacca acagcaaaaa tatgttcatc cgttgtattt
    10021 tggtatttat ctactttgat aaaccctttt ttgtccaatt ccacatttgt attttccaga
    10081 cctaattttt cggtattcgg tacacgtcca ccggcaaaaa gtacacaatc accagttaag
    10141 gtttcaccat tttcaaatag caccgtatat tcgtcattgt ttttagtaat ttctttagca
    10201 atatgatgtg cgtaagtttt tattccagct tcttggtaca tttggatcaa attgtccgaa
    10261 agcattttat caaacgttct aagtggtcgt tcttttcgat atgcccacat gacttcacta
    10321 cctaaaccac gaaatacacc tgaaagttca gccgcaatgt atccagcacc taaaacgatt
    10381 gctctcttag gtaactctgt taattcaaaa aatccatttg aatcaattgc gtattctcca
    10441 ccaggaatgg tcattttact tgcacggcct ccagtagcga tcaagatttt aggagcacga
    10501 taggtttcac cgtttacttc gatcgtttga ctatcgataa aagtagcgta accttttata
    10561 gcctcgacat gattgctatc taatcctctt tgataagcac cgtgtagaaa atcaatatat
    10621 ttttctcgtc tttctactag accggcgaaa tcaacatttt ttaaatctgc ttggataccg
    10681 taacttgagg catctcgttc aattgtttcc aaaatcgtac ttgcttgcca cataactttt
    10741 ttaggtacac aaccgacgtt gacacatgtt ccgcccaatt cattcgcttc aatcagcaaa
    10801 acttttgcgc catgcatccc tgctctgttt gctgaagcaa taccgccaga gccgccacca
    10861 attacgatgt aatcatatat ttgcattttg ttcctcctta ttgaagagat caatcaaaac
    10921 ctttatttaa cgatcctttt tctacagaaa acaagtgtaa cacttttctt gaattttgta
    10981 tgcgaagatg cttaaaacag ggatatatca gctttttcct tatttacgtt ttcggatcat
    11041 atctccaggt ttcaccggct gtgcgactgg catagttaaa atcatcattg gatttggtgc
    11101 tcggtcaatg gattcgcctt cttcattatg cataacttca acggtttgac tgaaatgact
    11161 gaatcctgga ccataaaatt cgatttcatc tcctacagaa aacaagtttc tctgacgtat
    11221 cgtagcaatc tgtgttgcct catcataaga taatacttca ccgacaaatt tatatactgg
    11281 gattttacga cgttcaccga ataattgttc gttttcagtt ggtgtattgt agtaaaaacc
    11341 tgtagctaat tctcgttgtg ctactttcca taactcgtcg atccattctt gcttgcagac
    11401 atagttttca ggatcttcca tataactgtc tacagccgct ttatagacat ttgacaccgt
    11461 agatacataa tggatcgatt tcattcttcc ttcgatcttg aagctgtcta cgccgttttc
    11521 aatcaattct ggaatatgtt cgatcattga catatccact gcactcatcg agaattcttc
    11581 ttccacttcg cctgtatcag ttaaactgtt tcgttcttga ccaaaaggca tatcgaacaa
    11641 tccatacttc cagcgacaag attgagaaca tccgccacgg tttgcatccc gcatcgacat
    11701 atggttggac aatgtgcatc gaccagaata agagatacac atggcaccat ggataaatgc
    11761 ttcgatttcg gtatccgtat ttttacgaat ctctgccact tcctccattg aaacttcacg
    11821 agctaaaacg acacgttcca acccttcttc tttccagaat tccaatgtct caaaattagt
    11881 tgctgaagct tgagtggata aatggatcgg cagacctggg gcttctgtcg cacaaatttc
    11941 gatcaaagct ggatcagaaa caatcactgc agaaataccg acatcacgca aactgcggaa
    12001 aaattcccct gctccatctt catttccttc atgggtgacc atattagcag caacgtatac
    12061 cttcgcatca tgttcttttg caaaagcaac tccttcagcc atttcttcat aagtaaaatt
    12121 acctgcacgg cttcttaaac catatgcatt cccgccaata tatactgcat ctgctccata
    12181 atggatcgcg gtttttaact tttccagtgt tcctgctggc gctaggattt ctggtcgttt
    12241 caattttctt tttactgtca tttctttcat catactcctt atttgatagc agaaggatca
    12301 atataaaaga atcctgtatc taattcacgg ttttcaggat gcaatttact gatttcgcta
    12361 gtcatttttt ccgctttttc ttgatcccag ctaccttcta aaatttgttt ttttgcttcg
    12421 gcgaatagtc gagtgatgtt tacgaatttt tcgcctggag taaataatcc gtccaatttc
    12481 catgtacagt aatgatgctg ataaagttca ttcaattcat tcgagagatt cagatcattg
    12541 ctggcaaaaa tatgtgtgcc atgactatct tcataaatag aataatgtgt ctcttctttt
    12601 ttaggttccg agataaaaag acctctttca cgatcttttt gttcgtcttg tttcgtatag
    12661 ttatagtaat tctgtagcag tggacgtttg gattgatgga tgcatgtagc accatacaca
    12721 agggtttcta caggaatatc gagtttttct tccatcgcct tcatctcttc aaaaggaact
    12781 tcacgagcaa gtactgctcc aactgcgcct tttttcgccc agaaattgat ttgacgtgcg
    12841 ctcgttacta atgtttcagc atcataaata tacggtatac gcaattcagg attttttttc
    12901 atcgtataaa taatacctgt atcaccaact gtgatcacat ctacgtttat ttcttttaaa
    12961 aaagccaaat attcaggtac atttttcatt ttttcaggat gaatgatccc atttacagca
    13021 atattcgctt ttttaccata cttgtgtgct aattctacca attgtcgctg ttcttctcgt
    13081 gtaaatgaag caggcagacg caatccaaat tgctcttcac cgaaatatag tgtatctgca
    13141 cctgcagcaa gcaactgttc tgcttgttca atagtttcta ctgtggttat gagttcgatc
    13201 ataattttct cctcctacaa cttcataata gtagcatagc tctaaaaact ttccaatact
    13261 tcttctattt aaagtcggat ttttgaaaat tatttcacaa aaaatcaaaa taaagttcga
    13321 tatattctgt ccaaatataa aaagagattg tgacaaaaat cttgtcacaa cctcttaatc
    13381 aagtcttact attataaaaa ttcagctaca caggccaagt aactataggg aacctactgt
    13441 ttccttttta ggtccgcgaa cattcaatgt gatcttacct tttgaagcac ctactgttac
    13501 gtggtcacct aaacgaattt ctccgccaag caaagcctcg ctcaatcgat cttcaatttc
    13561 tttttgaagt gcgcgacgga ttggacgtgc accatattca ggatcaaatc cagctttccc
    13621 gatcacatcg attgcagatg gtgtgatttt cacttgaata tcttgttctt tcaatcgttt
    13681 gataatcgct ttgctcatga tttggacgat tgtatggatt tcatctttac tcaatgaatg
    13741 gaagacgaca gtctcatcga ttcgattcaa gaattcaggt cggaaagctt tctttaactc
    13801 ttctaagata cgtttttgca tggctttgtg atctttagta acatcttgga cattgaatcc
    13861 gacatttttt tcttctcgaa tttgtgtcgc tccgatattt gaagtcataa tcatgattgt
    13921 atttctaaag tccacttttc tacctttaga atctgttaaa tgaccatcat ccaatacttg
    13981 cagaagtaaa ttgaaaacgt ctggatgtgc tttctccact tcatctaaga gaatcactga
    14041 atatggtttt tgacgaattt tttctgtcaa ctgtccacct tcatcatacc ctacgtatcc
    14101 tggaggagac ccgattaatc ggcttgtact gtatttttcc ataaattctg acatatcaac
    14161 acggatcagg gcatcttcac ttccaaacat gacttctgaa agtgctttgg ccaattctgt
    14221 ttttccgaca ccagttggtc caaggaacat gaatgaacca attggacgat caggatcttt
    14281 caatccgctt cgtgcacggc ggatcgcacg tgaaactgct ttgacagcct catcttgacc
    14341 aacgacacgt tcatgcagaa gtccttccag ttctaacaag cgttcgcttt cttttttctc
    14401 caactgctgt agagggacac cagtccactc cgatacaact gtagcaacat cttcttctgt
    14461 tacacgatca gaataacctt gctcctgttt tgcttcaatt gcagaaactt tttgcagctt
    14521 tttacgtagt gctttttctt gtctgcgtaa ttgagcagca ttttcaaagt cttgtttttg
    14581 gatcgctgct tccttttctt gtactagttc atcgatttct agtttgatca cagttgattt
    14641 tgttaagtga tcggtttgat ccaaacggac tttcgctgct gattcatcga tcaaatcaat
    14701 tgctttatcg ggtagttgac gagaagtgat ataacgaaca gaaagattga ctgctgctcg
    14761 tacagcttca tctgtgatct ccactccatg gtgctcttca tatcttgtac gtaatccttg
    14821 aagaatcact tctgcttctt caggagttgg ctcatctact tgaatgcgag caaaacgtcg
    14881 ctctaatgca gaatcttttt cgatatattt ttgatattca tctagggtcg ttgctccgat
    14941 cgtttgtaat tctcctcgag ctaacgccgg tttcaagata ttcgaagcat caattgctcc
    15001 ttctgctcca cctgcaccaa ttaaggtatg caattcatca atgaataaga ttacttgacc
    15061 atcattatag atttcgtcga tgaccttttt cattcgatct tcaaattcac cgcgatattt
    15121 cgtaccagca accaaagatc ccatatcaag catcatcagg cgcttttctt gcatgtcttc
    15181 tggcacttca cctaaaatga ttttttgagc taacccttca gcaatggctg ttttgcctac
    15241 accaggttca cccaccagta cagggttatt ctttgtccgt cggctaagaa tctggataag
    15301 ccgtttcact tctctcgaac gaccaacaac tgggtccagc ttgttttctt ttgctaattt
    15361 cgtcaaatca cgtgctaatg aatctagcgt aggtgttcct tgcggtgttt gccgtttatc
    15421 ttgtacattt acatttctac gacgattcat tccttttcca gcagaatcac cagctagccc
    15481 cattttttgt ttcagaactt gacgggcttt tgaaaggctg atacctaagt tgatcatgat
    15541 tcgagtagcc atgatacttt catcttttaa taagctcatc aaaatatgtt ctgttccaac
    15601 tttttgagaa ccagttttct tcacttcgct gctagctaaa gcaaaaactt gtttcattct
    15661 tggtgaatat ggaagaaaga ctcctttagg gtaagaacgg ataccaccat aaccaatcag
    15721 atgttcaatt tcttcataaa tttccgtttc attcaaatcc atttcacgta atacttttcc
    15781 agcaattcca ttttgctcga ccactaaggc tagtaaaaca tgttctgaac taactgattg
    15841 atgtttcaac cgttttgctt cttcttgtgc aatttctaat actgcttggg ctctttcagt
    15901 aaaaagttct tccatctaat ctcacttccc atcttcataa cttaaacgtt ccagaaatgc
    15961 tcggagaatc cgagcacgtg tatgatcttc atattcattg aaattcaatg tgttttttgc
    16021 aattgcactc aacatcaagt ttccttcttt ttttgtaatt atttggtctt cataaagttt
    16081 ttgaataata gcaaaagcat ttttctcact gattgtatca tcaaataact gatttatctg
    16141 ctcaagtaat tgttttttat ctgaaatcct tacttttgca attcgtatat aaccaccacc
    16201 accacgtttg ctttctacta gataaccacg ttggatggta aaacgggtat taatcacata
    16261 gttgatttgt gaaggaacac agttaaagag gtctgccatt tcaatccttc gaatctcgat
    16321 catttcacta ttttccagaa ttttctttat atatgattca attaaatccg aggtattctg
    16381 atgtgccatc ttattcattc cctttgacta atattgacct taattataac gaatttgata
    16441 atagaaagaa agaagaacgc tttttgttaa ataaatcctt tagaatcaac aaaaaaaaat
    16501 acggaatata ctattccgta tcgacgcgcc caagaggagt cgaaccccta accttttgat
    16561 ccgtagtcaa acactctatc cagttgagct atgggcgcat attcaattta aaaaaattat
    16621 aaatcatttg aaaacaaaaa gcaagataaa aaaaatcggg aagacaggat tcgaacctgc
    16681 gaccccttgg tcccaaacca agtgctctac caagctgagc tacttcccgt ttaaaaaata
    16741 aaaaagac
//
LOCUS       DACDAF010000064        16563 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.064, whole genome shotgun sequence.
ACCESSION   DACDAF010000064 DACDAF010000000
VERSION     DACDAF010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16563)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16563)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16563
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.064"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(63..1172)
                     /gene="rpoD"
                     /locus_tag="IVZ69_001928"
     CDS             complement(63..1172)
                     /gene="rpoD"
                     /locus_tag="IVZ69_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HAP8184004.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(1196..3037)
                     /locus_tag="IVZ69_001929"
     CDS             complement(1196..3037)
                     /locus_tag="IVZ69_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HAP8184005.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(3219..5612)
                     /locus_tag="IVZ69_001930"
     CDS             complement(3219..5612)
                     /locus_tag="IVZ69_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP8184006.1"
                     /translation="MFLILEHARLKHVIIFESWRKMEKKKMNGLTQQEVVQKMASGQQ
                     NDYQEDASKSTKQIFSDNILTLFNFLNFGIGICLLFVGAYSNMAYLAIIVVNIVIGIY
                     QEIHARNLVRKLSIVSQSEVLVIRDGKEQSISTKELVLGDLVKIGAGEQIPADLQVIS
                     GRAEANEALLTGESDLIVKETGAELLSGSFLTSGSVMAEVIRVGADNYAVRLTSEAKT
                     HKAIRSELVDSIRKVSKFTSFVIIPLGIILFLEALFIRDASIKISVIASAAALLGMLP
                     KGLVLLISIALTTGVTKLAKKRILVQDMYSIETLAHVDTLCLDKTGTITEGKMSIQRV
                     EALHPLYEKAIPEIMGTYLAESSDNNITMRAMRDYFELSNRYDVTNKVAFSSDRKWGA
                     MEFPELGVVYVGAPERLVEEDRLPDSLKTAQANGYRVLMLGIAPNQQLNEEKPAFVEP
                     VALFEIDDPIRKNAQETLAYLHEEGVDLKVISGDNPFTVSNIARRAGLPNYDAYVDLS
                     QITEEMEVREAAHRYTVFGRVSPQQKKLLVNELKESGRTVAMTGDGVNDVLALREADC
                     SIAMAEGDGATRQIANLVLLDSDFTTLPEVLFEGRRVVNNVTKVSGIFFIKTIYSFIL
                     SIICAVTAIGFPFIPIQITLIDLAIEGYPSFFLSFEQDKRKITYRYLPTALINALPNA
                     LLVVVNIIAVYLLGKTFAWGNAETTTLMYYLLIGISCMAVVKACYPFNPLRIFLAVTT
                     IVGIYVAAMLFHGILEVNLGLGESVGYFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(5719..6579)
                     /locus_tag="IVZ69_001931"
     CDS             complement(5719..6579)
                     /locus_tag="IVZ69_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HAP8184007.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(6638..7270)
                     /locus_tag="IVZ69_001932"
     CDS             complement(6638..7270)
                     /locus_tag="IVZ69_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HAP8184008.1"
                     /translation="MKRKRLSIIRILFYMIILTVIGAVLFLGGRTYRSVKRVESYQIE
                     ITTAAKNYHMENYENLIKAIILTESKGKGTDLMRSSESLHGEAEIIDNPADSIDQGVK
                     YLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHGGENTVELAEAYSKDVLSPLLG
                     NEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKMNEKIIETYEKVFK"
     gene            7479..8198
                     /locus_tag="IVZ69_001933"
     CDS             7479..8198
                     /locus_tag="IVZ69_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP8184009.1"
                     /translation="MKKEKKYAKMPDGSEIYYEKSGQGFPLFLLHGNDGSGRFFSEQV
                     PVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEKIDQADFLGFSDGAN
                     LALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVWLLSLFRPSLRKNLL
                     VIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKTIPKASFVLVKEQGH
                     ELARKDPERFNREVLQFLSET"
     gene            8224..10815
                     /gene="mprF"
                     /locus_tag="IVZ69_001934"
     CDS             8224..10815
                     /gene="mprF"
                     /locus_tag="IVZ69_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HAP8184010.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLVSVLPMIGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDP
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(11003..12190)
                     /gene="tuf"
                     /locus_tag="IVZ69_001935"
     CDS             complement(11003..12190)
                     /gene="tuf"
                     /locus_tag="IVZ69_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HAP8184011.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            12558..12914
                     /locus_tag="IVZ69_001936"
     CDS             12558..12914
                     /locus_tag="IVZ69_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP8184012.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(13155..14159)
                     /locus_tag="IVZ69_001937"
     CDS             complement(13155..14159)
                     /locus_tag="IVZ69_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HAP8184013.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            14325..15176
                     /locus_tag="IVZ69_001938"
     CDS             14325..15176
                     /locus_tag="IVZ69_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HAP8184014.1"
                     /translation="MNSLTSTYRLLNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQPTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            15193..15438
                     /locus_tag="IVZ69_001939"
     CDS             15193..15438
                     /locus_tag="IVZ69_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184015.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            15625..16329
                     /locus_tag="IVZ69_001940"
     CDS             15625..16329
                     /locus_tag="IVZ69_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184016.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT         4872 a         3416 c         2929 g         5346 t
ORIGIN      
        1 ttttttcttt taaaataaac caaacagttt tactgatttc tcttctggtc aatagtccac
       61 gcttattcta agaaatcttt taattgtttt gaacgagaag gatggcgcaa ttttcttaat
      121 gctttagcct cgatctgacg aatacgttcc cgagtaacac caaacacttt ccctacttct
      181 tccaatgttc tcgtccggcc atcatctaaa ccaaaacgta agcgaaggac attctcttcc
      241 cgatcagtca atgtatctag tacatcttcc aattgttctt ttagtaactc ataagctgcg
      301 tgttctgctg gacttgttgc ttcctggtct tctatgaaat cacctaagtg agagtcatct
      361 tcttcaccga ttggcgtttc aagggaaaca ggttcttgcg cgattttcaa gatttctcgg
      421 actttttctg ttggaagatc catttccgca ccgatttctt ctggcgtagg ttctcttcca
      481 aggtcttgca gcaattgacg ttggatacgt atcaatttat taattgtttc aaccatatga
      541 actggaatac ggatcgtacg tgcttggtca gcgattgctc gagtgatggc ttgacgaatc
      601 caccatgtag cataggttga aaacttaaat cctttgcggt agtcaaattt ttcaactgcc
      661 ttcatcagtc ccatgtttcc ttcttggatc aagtcaagga actgcatgcc tcgtcctaca
      721 taacgtttag cgatacttac tactaaacga aggtttgctt ctgccagacg ctgtttcgct
      781 tcttggtcgc cttcttcgat tttcaatgct aacgctactt cttcttccgc agttaaaagg
      841 gagacacggc caatttcttt cagatacata cgaaccgggt cattgatttt tacaccggtt
      901 ggcgcagaaa gatcttctgt ttttgcttgt tcagcttttt tctcagcact cttcaagctg
      961 tgaattgatg gatcaccatt ttcatccacc acactgatac ctgcgtcttc aatcttttgg
     1021 atcaatttgt ccatttcatc tgcattcaaa gtgaatggtg tagcaagctg attggataaa
     1081 tcatcatata caacttgtcg tttgggtttg ttttctttga tgaaagctgc tactgctgct
     1141 tcatacgttt ttttatctgt tccatttgcc ataaaagaag gccccccttg agtagctatt
     1201 tggcttgttt taactgtttc gttaaattga tgatttcaat cgtcaattca agctcaagct
     1261 gtttgtttcc agttcgtctg gcttcttgct gcatttgttt ttttaatgtt atttcatcag
     1321 ctaagccaga tttgctgatc acatctagca agtcttggat ttctcgtggc gaactttctt
     1381 ctgccaccgg taaatattcg atttccacca ccaaccgcct taaattttca tcttgcaaaa
     1441 agtctaaaaa ctctgcaagg ttgaattcat aatgttgtga gacatatgca tcgaataaaa
     1501 aataaacttc tgcatatgca tcatgaataa actgaaattc tcgttctttt aaaatattac
     1561 ggacagaaac ttctttaaat gcacgatata atagaatctg ctctgccttt tctacttgcg
     1621 tcaaaggtct ctttttccgt gcagtttctt gtctcgtaac ctgagtgtgt tgactttcct
     1681 gaggttcttg acgattttgc tgatttgtcc ttcgaagatc gcgcagttgt ttttgtatcg
     1741 tctctctgcc gatctgaaac tctgttgaca gttgagatag atacatatct tgttcgattg
     1801 gtgaaacaac tcggctaagt tcaactagta attcttcgag gtattcgatc ttgtcttttt
     1861 cattatctaa atttttccct tgttttaaat aacgtgattt aaaagtaaag actgtttcgc
     1921 gcccatgagc cactaattct tggaaagatg cttctccata cttacggaga tattcatcag
     1981 gatcaagctt ttctggaacg actacgacag aaagtgctaa tcgactgttt tgccgaagca
     2041 attcaatccc tcgattggtt gcttcaaaac ctgcgttgtc tccgtcatag caaaagacca
     2101 attctttcgt cagcttttcc atttgttgga tctgttgagc tgttagactt gtccccatag
     2161 aagctaatcc agttttgata ccagcctgcc atgcagcaat cacatccata aacccttcga
     2221 acaacaaaat ttctccgttt ttccggatat cgcttcttgc tttatcaaga ttaaataaaa
     2281 cttgtctttt attgaacagt tctgtttctg gactattcaa gtatttgggc tgatcttttt
     2341 cctgcccttt ttcaggtgca agccagcgtc ctgaaaaacc gatcgtctgg ccttgagaat
     2401 tacgaagtgg aaacatcact ctttgataaa aacgatcaga catacggcca tcatcatgcg
     2461 tgacaaacaa tccagagcgt tctaacaatt catttgaaat tgattcattc ttgaatactt
     2521 gctgaagaaa agaacgctca ttaggtgcaa aacctatgtt gaattcttca attaattcta
     2581 aagacaaccc acgactttgc aaatattcta aagctggctg tccagctttt gtatgcaata
     2641 gcatgtgatg atagatttcc gctgcttttt catgagcagc aatcagtttc cccgtagcag
     2701 attcaggatt ttggacagct atagtacgct gacgccattg atcttctaac ggtatctgtt
     2761 cgaagtctgc cacttttacc actgcttctg gaaaacttag accttctagt tcttgaagaa
     2821 aagtaaacac gtttccgcct ttaccacaac caaagcaatg aaaaatctgc ttgtcttctg
     2881 caacagaaaa agacggtgta cgttcttcat gaaaaggaca cagccccaag taatttttac
     2941 cagacttttt caactggaca tattgtccaa tcacctcaac gatattcgtt tgactgcgta
     3001 ctgtttcgat aacctcttga ggaatccgtt gagccatttt ttcaccccct gctctattga
     3061 tatcttttgg gtttaacaga agatatttca ggagaataac cggtaaaaaa tcgcactaac
     3121 tgaaatcagt gcgattttaa aggacacaat tatacatgtt tgattgtatc atatttcatt
     3181 gctttttcaa gtataacaca tttctatctc attaagcatc aatttgctac tcttttcagt
     3241 aactgatttt gaatatcagc cttccagtac aatactcgaa gaacaatatt tacgagcatg
     3301 aatacaaaga agtatcctac gctctctccc aaccctaagt ttacttccaa aattccatgg
     3361 aacagcattg cagctacata tatccctacg atcgtcgtta ctgctaggaa gatgcgcaat
     3421 gggttgaagg gataacaagc ttttacaact gccatgcaac tgatcccaat cagcaagtaa
     3481 tacatcaaag tagtagtttc agcatttccc catgcgaatg tttttccaag tagatacacc
     3541 gcaatgatat tcactactac aagcaaggca tttggtaaag cattaataag tgctgtaggc
     3601 aaataacggt aagtgatttt tcttttatct tgttcaaaag ataaaaagaa ggaaggatac
     3661 ccttcaatcg ctaaatcaat cagcgtgatt tggataggga taaacggaaa tccaattgct
     3721 gtaacggcac atataatcga taaaataaat gaataaatcg ttttgataaa aaagatgcct
     3781 gagactttcg tcacattgtt gaccactcgg cgtccttcaa acaggacttc tggcaatgta
     3841 gtaaaatcag agtccaacaa taccagattc gcaatctgac gtgttgctcc atcaccttct
     3901 gccatagcaa tgctgcaatc tgcttctctt aacgccaaaa catcattcac accgtcgcct
     3961 gtcattgcaa ccgttctgcc gctttctttc aattcattta ccagcaattt cttttgctgc
     4021 ggactcactc gtccaaaaac cgtatagcga tgagcagctt ctcgcacttc catttcttca
     4081 gtaatttgag aaagatcgac atacgcatca taattcggta atcctgcacg tctagcgata
     4141 ttggagacag taaaaggatt gtctccagaa atcactttca gatccacacc ttcctcatga
     4201 agataagcta gtgtttcttg agcgtttttt cggattggat catcgatttc aaacagagca
     4261 accggctcaa caaatgctgg tttttcttcg ttcaattgct gatttggagc gatccccaac
     4321 ataagtacgc gatagccatt cgcttgggct gtttttagac tgtccggaag ccgatcttct
     4381 tccaccaaac gttcaggcgc tcctacgtac acgactccca gttctggaaa ttccatcgcg
     4441 ccccatttgc gatcagaaga aaatgcgact ttgtttgtca catcataccg attagaaagc
     4501 tcaaaataat ctctcatagc ccgcatagtg atgttgttat cactgctttc tgccagatac
     4561 gtccccataa tttctgggat ggctttctcg tacagcggat gtagtgcttc tacccgctgg
     4621 atactcattt tcccttcagt aatggtccct gttttatcca agcataatgt atcgacatgg
     4681 gccagcgttt caattgaata catgtcttga acaaggattc gtttttttgc cagtttggtt
     4741 acccctgtcg ttaatgcaat acttattagc aataccaaac cctttggaag catgcctaac
     4801 aaagctgctg cagatgcaat aacagaaatt ttgatagaag catcgcggat gaacagtgct
     4861 tccaaaaata gtatgatccc caaaggaata atcacgaaac tagtgaattt ggatactttg
     4921 cgaatcgaat ctacaagttc agaacgaata gctttgtgag tctttgcctc gctagtcaag
     4981 cggacagcat aattatctgc acctactcgg ataacttcag ccatgacaga accgcttgtc
     5041 aaaaagcttc cagaaagcaa ttcagctcca gtttctttga caatcaaatc agattcgcct
     5101 gtcaaaagag cttcatttgc ttctgcccgt ccagatataa cctgtaaatc ggctggtatc
     5161 tgttctcctg ctccgatttt taccaaatct cctaatacca gctctttagt agaaatcgat
     5221 tgttctttac cgtcccggat cactagtact tctgattggg aaacaatcga taatttccgt
     5281 acaagatttc ttgcatgtat ttcttgataa attccaataa cgatattgac gacaataatt
     5341 gctaaatacg ccatgttgga atacgcacct acaaataaca gacaaatccc aataccaaag
     5401 ttcagaaaat tgaataacgt caatatatta tcgctgaata tttgttttgt actttttgat
     5461 gcatcttcct ggtagtcatt ttgctggcca gaagccattt tctgaactac ctcttgctgt
     5521 gtaagtccat tcattttctt tttctccatt ttccgccaac tttcaaaaat aatcacgtgt
     5581 ttaagtctag cgtgttccaa gattaaaaac aacttgtttt tataaaattt atagaaaaac
     5641 acacgaatga ttttacaaaa aagatgccaa cctttttgtt tgaatcaccc gtgtgctgtt
     5701 tttattatca atctatcttt acttatattg ttcctccaaa cggctcatcc accaacctag
     5761 tgctgtaccg gctataaaaa gaacaggaca agctagtacc ccagcaactc ccaatcccgc
     5821 gtaatcggta ggaatgatca taatcgttga agcaaaaact acacctaaaa tgaaatggaa
     5881 tagcttgcta tatgcctttg agaaaatgta atccatgatt tttgacaatc caagaacaca
     5941 aagaatccca ccaattccga tcggcacaat cacttcaagt cgtacttctt taaatccgtc
     6001 agccatcgct ttatacaatc ccatatacac caaaaaatta gaagggctca atcctgggac
     6061 gatcataccc aaaccaatca atccgccggc aatcagccat gttccaaaat tctgatcgac
     6121 ttgcccgtca aataattgag cgccgtataa taaaaacaaa taagccagaa caaaagtaac
     6181 aaccatgatg atcacatcag aagtatctct tccttttttc cctgcttctt tccataacgc
     6241 aggaacagtt ccagcgatac atccgacaaa aaaccataat atcgttgttt catacgcacc
     6301 taataaaaaa ctgactaaaa aagaaagtag aaagatgcct gtcactccgc ctagaccaac
     6361 aggcagaaaa aacaaaacat tttctttgaa attttttgta aggtgggcta aaaaagaaat
     6421 cagccgctca tacatgccaa agacagctgc taatgcacca ccgctgactc ctggcaagat
     6481 aaatcctgaa ccgataaaca ttcccttcac aaaccgtaac atccagtctt tggttgtgta
     6541 ccccacttct tgattttcca ttttttgcct tttttccact atttgcgcac tccttctttc
     6601 atttaatttt attcatgatt gaacatttcc tgctatttta cttaaagact ttttcatagg
     6661 tctctattat tttttcattc attttgacaa tatcaggata aaacatgtta cctccattat
     6721 gatagagata gccgccattg taaagcaagg actggatccg ccaatatcgg tattgtttcc
     6781 cttcctcatt tcctaaaagt gggctcagca catctttaga atacgcttct gctaattcta
     6841 ctgtgttttc tccgccatga ttttttacat aggcaatata atctttccca aaattatatg
     6901 cttggacagc tgtccataaa tcgcatcctt gtttctttgc ttctactatc atttccgcca
     6961 aatatttgac accttgatca atactgtcag ctggattatc aatgatctca gcttctccat
     7021 gcagactttc cgagctccgc atgagatctg tcccttttcc ttttgattcg gtcaatatta
     7081 tcgccttgat caaattctcg tagttttcca tatgataatt ttttgcagct gttgttattt
     7141 ctatttgata gctttccact cgttttaccg aacgataagt tcttcctcct aaaaacaaca
     7201 ccgcaccaat aaccgtcaga atgatcatgt aaaaaagaat acggataata gataatcgtt
     7261 ttcgcttcat ttcatcacct agttattttg acatcttttt ttatcttact atttctttat
     7321 cttcttggct atttcttcct tgatttctgt gtacgcctta agaaaaaatg aattttcctg
     7381 tattttttgt catcttacga aaatgatcgt tgtttttcag taaaaacaat tgcccaatga
     7441 ctgatataat cgttatactt tacacagtag gtgattatgt gaaaaaagaa aagaaatatg
     7501 caaaaatgcc agatgggagc gaaatttact atgaaaagag cggtcaaggc ttccctctct
     7561 ttttactgca tggcaatgac ggcagcggcc gctttttttc agaacaggtc cctgtactcg
     7621 aacgctacta taccgtgtat ctagtagata gccgaggaca tggtcgttcg acaaacgaag
     7681 catctatgtt gaattttcag ttaatggccg aggatctgaa tacgatcatg ttgctggaaa
     7741 aaatcgatca ggcagatttt cttggattta gtgatggagc aaatctagca ctggtatttg
     7801 ccagcagctt ccctaaaaaa gttcatcgat tgattttaaa ttctggaaac acgcttgtta
     7861 aaggcgttcg tttttctgcc agagtcatca gtaatattca ttatgcatgg gtatggttac
     7921 tctctttatt tcgcccaagt cttcgcaaaa atcttttagt tatcaaactt ttgctgcatg
     7981 acatcgggct tacagaaaat gatttaaaaa aaatcaactc ccccactttg atcatcgtgg
     8041 gaaaaaaaga tgtaatcaag ctaaaacatt ctttgtatat agctaaaact ataccaaaag
     8101 cttcctttgt gcttgtgaaa gaacaaggac atgaattagc tagaaaagat cctgaacgct
     8161 tcaatcgaga agttcttcaa tttctttctg aaacataact attaggaata gaaggtgatt
     8221 tatttgttaa aaaataccat acaatggctg aaaaaccacc taggactgtt caaaacaatc
     8281 tttttgattt ctgtcattgt cattattgtc ggtgaattga tgtccatcgg taaaactcta
     8341 tctatccagc aattaggaga aacgtttgcc actatacctg tatggaaaag cggacttatg
     8401 ctgttgattg gtcttgtctc tgtgttacct atgattggtt atgatattat tttgaatcgg
     8461 atgcttgaac aaaagcagaa tcctcgttac ttgtttgaga caagctggct gatcaataca
     8521 atcaacaata ttgccggttt cggcgggttt gttagtgtgg ggcttcgctc tgaactatat
     8581 ggacaaaaga aagagagcag aaacgtgatc caagcattat cgaaagtttt cttgtttttg
     8641 atggctggac tttctattta cagtctgctt tcttttttac ttgtagtctt cacgccagtt
     8701 gctccttttt tgaagcaata ttggatatgg ttgatcggcg gcggtctata ttttcctgtc
     8761 gtctttttat ttactacttt caaaaagaaa ggattccttg gtggtacctc acttaaaact
     8821 caaggacagc tattgctagt ttcattgttg gaatggaccg gtgtcctgtt tagtttcctt
     8881 tctgttggtt atttaatgga aatccggatt gatctgtggc aaacaattcc gttattcatt
     8941 gctgcttcag tgataggaat cgtgtctatg attccaggag aaattgggag tttcgatgta
     9001 atgatgatta tcgggttgtc cgctattggt gtgccaagag aaatagtcgt tgtgtggatc
     9061 ttgctctatc gcctgttcta ctacatcatt ccgtttttga ttggaatcgt ctttttcttc
     9121 aaaaatatcg gttccacttt tgatcagcgt tattctggta tccctaaaca attagcaaca
     9181 gaaattgcgc ataaaatcgt ggttgtctta ttatactttt ctggaatcat gctagtactt
     9241 tctgccacta tcccgcaagc ttttacagag tttcgctggc ttcatagttt gaacccattg
     9301 aaatttcatt ttattatcca atttcctagt atactattgg gatttctttt aatcattatg
     9361 ggcagaggga tcgcagcacg tgtgaaacga gcatatttgc ctacaatctt cttgattgtt
     9421 ctagctttac tttatgtttt attaagtgat tttagtttca caccggtggt tttcttgtct
     9481 attctgcttc tgatcattct tgcttctaaa aacgaattat ttcgggaaca attgatctat
     9541 tcatgggagt ggcgtacgat cgatggaatc attattggtg cactgtcctt gctttacatc
     9601 gttattgggg tatacaatct gccggatttc cctcatcggc gtcaccattt tatttccttt
     9661 ttcttatttc cttctgaaaa gatttggttt tcgggattgt tggccatcat cgctgttagt
     9721 ttcatgatcg ttctatttgt tcatttcctt caaggagaaa agaaacagat tggcgaagcc
     9781 tttaatgaag aaaaggccct gaagatcctt acaacttatg gaggaaactc cgatagtcaa
     9841 ttgatcttct taaaagataa gcggatgttt gcctatgaaa aagacggtga accaactgtt
     9901 cttctccaat tcgcttgctt caataataaa tgtattgtaa tgggtgatcc ttctggtaag
     9961 aaagaagatt ttccagaagc aatcgaagct tttatcgaag aaacagatcg actatgctat
    10021 ttaccagttt tctacgaaac aagcgaagag attgttatga ttttgcatga attcggctac
    10081 gatttcatta agatggggga agaagcttat gtagacctga atagttttac aacttcaggg
    10141 aaaaaaatga agggcactcg tgctgtcttg aatcggatcg aacgagaagg atttacattt
    10201 gatgtcttac aaccaccatt ttctactgag caaatgagta ctttcaaaaa tatctctgat
    10261 aattggttgg gttcacgaaa ggaaaaaggg ttttctttag gctttttctc tgaagattat
    10321 ctacaaagag cgcctattgc agttgtcaaa aatacccaag aagaaattgt cgcttttgca
    10381 acgatcatgc ctacttacac gaacaataaa gtaggaacga ttgatctgat gcgatatgat
    10441 cctaaaaaag caccttctgg cagtatggat ttcttgttct tgcatttgtt tgcctatatg
    10501 aaagaagaac atatccaatg gttcaattta gggatggccc ctctttcaaa tgtcggaact
    10561 tccagaaaga gttttttaca ggaaaggatt gcatacttgg tttacgagtt tggttctcat
    10621 ttttattctt tccatggatt aagagaatat aaaagcaagt acgctacaaa ctgggtctca
    10681 cgttatactc tatattctag agatagttgg attgcatatg ttatgattgc tttgctgatt
    10741 attgataatg cgccagttga gcagacacaa ggtagaataa gtggtttgaa aaaatggata
    10801 cgaagaaagt attaaaaact gcataccgat agatgaacac tctcatgatg aataaaagag
    10861 actgaagtaa aacgaaagtt catgcttcta caatctcttc ttatacaatt gaagaacaaa
    10921 gagcggtcca aacagaaatc ctgtttggac cgctctttta ttttaaacat ttttcattac
    10981 caaaatattc gagtcgcgtt tcttatgctt cgatctctgt aacgatacct gaacccactg
    11041 tccgtccgcc ttcacgaatt gagaatgtcg ttccgttttc aacagcgatt ggatggatca
    11101 agtcaacatc aatcgtcacg ttgtcaccag gcatgaccat ttctgtatct tctggcaatg
    11161 tgattgttcc tgtaacatca gttgtgcgga agtagaattg tggacgatag ttgttgaaga
    11221 atggagtatg acgtccacct tcttcttttg tcaacacgta cacttctgct ttgaattttg
    11281 tatgtggagt aatggaacct ggtttagcaa gcacttgtcc acgttcgata tcgtcacgtt
    11341 ggatcccccg taacaacacg cctacgttat ccccagcttc cccgtaatct aacgttttac
    11401 ggaacatttc tacacctgtt acaactgctt tttgtgtttc aggtttgatc cctacgatct
    11461 ctacctcatc accgacacga acagcaccac gatcaatacg acctgaggca acagttcctc
    11521 gacctgtaat tgagaagacg tcttccactg gcaatagtaa tggtttatct gtatcacgtt
    11581 ctggtgttgg gatatattca tctactgtat ccatcaattc cataatagca gcttcagcat
    11641 ctggatcgcc ttgcaatgct tttaatgcgg aacctttgat cacaggagtg tcatcgcctg
    11701 ggaaaccata ttcgctcaat aactcgcgaa cttccatttc taccaaatcg atcaattctt
    11761 catcatcgac taaatcaact ttgttcaaga aaacaatcag gtattttaca ccaacttggc
    11821 gtgacaataa aatgtgttca cgtgtttgag gcatcggacc gtcagttgca gaaacaacta
    11881 agattgcacc atccatttgt gctgcccctg taatcatgtt tttcacatag tccgcgtgtc
    11941 ctggtgcatc aatatgcgcg tagtggcgtt tttctgtttc atattctacg tgtgcggtat
    12001 tgatcgtaat cccacgttca cgttcttctg gagctgcatc aatactagca tagtcttgag
    12061 gatttgctag gccttttttg cctaatactg tagtgatcgc agcagttaaa gtagttttcc
    12121 catggtcaac gtgtccaatc gtaccaatgt taacgtgtgg tttacttctg tcataatgtt
    12181 cttttgccat aatttacaaa cctcctaaat aatatagatc actgaaaaat ttcagctctc
    12241 acctttttat tatagtcttt ttttgactaa atcaaaaaga atacgtccga cttacttttt
    12301 gtaagattcg aactaagctt attatacgtc aatattggtc aaagtcaact aagagcactc
    12361 gcttgtctta tacgcgaaaa aagtaccttt tataaataaa aaaatgtgtt ttttgagaaa
    12421 aacttcaaga tagtccttaa ctttcttttg aagcaataag aacaaaatga ggaaaagttt
    12481 aaaattcagc tgttgccaac aactttcaat agacgaaatc ttctatttcg ttaataataa
    12541 ggaaagaggt gaagtacatg aaaaaattaa ttggcgtact tgtcgtttta ggcatatttc
    12601 tcggcggaag ttttgcagct tatcattatt tttacggcgg cgaagcttat tatacaaaaa
    12661 tcacgacgaa tggcgaaatg tcagctaccc aagcagataa cggagagaaa ttcacgactt
    12721 atacctacaa gcaagcggct tataataaag atggtgaaaa aaaacaggtg acgcttcgcg
    12781 aagaaagaga acatccatta aagatgaatg cgtatcttaa actcaaagtc aatcctcgta
    12841 aaggtgtatt aagctgggaa gaaataaagg cttctgaagt gcctaaaaat gcggcagaaa
    12901 aaatcgataa ttagtaaatg gtcttaaaat tttattagat aaaaagaggc tgggacagaa
    12961 gcgtttaact ccaagaaata agaaggagtt gcttctgctt ccgccgttta tacgtgttta
    13021 gagcgtgaga caaaagtgtt ctttactttt gtctcacgct ctttttttgt tatattcgtc
    13081 ttttccgatc cttctcttga cacaattcat ttaactgatc actggtactt gaacacctaa
    13141 tgttctagtc atttttataa acgattcaat acttcatcca catttttgat catcacggat
    13201 atcgtaccat ccggattatt cacaaattca atcaaatctg ggttgcgata tacatctact
    13261 ggtacgatca gttcgatccc gtttgatagc ttgaattttt gttttccaaa ttttttctca
    13321 gaaatttctt gtacttcttt tacaggaggt gcttctggga caaatccttg ctcttgtact
    13381 tcttctttaa aagccatttt tgccgtgatg ttttccttga agactttttc cgcaatcatc
    13441 tcatgatcca accgaccttt ttcttctatc gtatcataga cagcttcttt caaatcagcc
    13501 atgatatcaa attcttctgt ctcaaatttt tttccaagat gcttggctac tttttggatc
    13561 acttttacat tttcttctaa agaaggtgca ggaacacttt cgatcactct tccagaaaaa
    13621 taaagctctt ttttgccaga aaactcatat tttttttcaa ttaattcgta ggtccaatca
    13681 gtcaaattca cagcgaatgc ttcatctgct ttttgtgttt tcgcccctag aattgctcga
    13741 ttcaaaatca agcggttgtc gatccctgct tcgtctgctt caacaaagtg agtgtaagcc
    13801 tcacgataat tgactttcaa taaagataag tacatcactg tatctaattc atacaaaaca
    13861 acaaatacat ctgcactagg tgcttcttca ctttcttggt agatatcgaa ccaccgctga
    13921 acgattgctt cacttgcttc cacaaaattt tcttgagcga ttttaagtga ttcaacgatc
    13981 atgctttctt ctgctagttg tccagttttt gtttgagcag aagagatttt ttggatcttc
    14041 ttttgaagaa aatcacgaat atattctttt gtcagatcca gctctttttg tgaaaagact
    14101 ggagaaccag tttctctgtc aataatatgc agaattgctt tttttaaata gatatccatt
    14161 ttctcattcc cttctgtctt agtttacgga aaaaaaatca aaaataccag aatcaaaatc
    14221 attttctttt aaacaaaaat ttcaagagta gaaacaaaat ggattctttt tttcgaaaaa
    14281 tgcgctacac ttatagttga acgaataaaa aaggagctga aagtatgaat tcattaacaa
    14341 gcacttatcg tctattaaat ggttacgaaa tcccggtagt aggattcggc acatggcaaa
    14401 cacctgatgg ggatgtcgct gtttcctctg ttaaagaagc gctggctgca ggttatcgcc
    14461 atatcgatac tgcccaagga tacaagaatg aagaaagtgt cggccaagcg attaaggaaa
    14521 gtggaattcc tagagaagag atattcttga caacaaaatt atggaatgca aaccacagct
    14581 atgaacttgt gatgtcttct tttgaagaat cattgaagaa gctccaaaca gattatttag
    14641 atctgttttt gatccactgg ccaaaccctg ttgcttttcg tgataattgg gaacaagcaa
    14701 atgcagatac atggcgagca tttgaagaac tgtatgaagc aggtaaaatc aaagcaatcg
    14761 gtgtgagcaa tttcttaccc caccatctag atacactagc aaaaacagca aaaattatgc
    14821 cgatggtcaa tcaagttttc cttgcaccag gcgaattaca gccaactgta gttgagtatg
    14881 caaaaaaaca tgatatgatc ctcgaagcat atagtccatt aggcactggt aaaatcttcg
    14941 atgtgcctga aatgaaacaa atcgctgaag cacatgacaa gacgattgca caagttgctt
    15001 tgcgttggtc gctgcaacac gaattccttc ctcttcctaa gtcagtgaca ccaagcagaa
    15061 tcaaagaaaa tactgaatta tttgattttg aattaacaga agaagaaatg aaacaaatcg
    15121 atcagttaga tggtgtagtc ggcaaagcaa aagacccaga tactacccaa ttttaagtcg
    15181 aaaggtgatt ttatggatcc aatcgaacgc ttgaattctc tctcggaaga agttacccag
    15241 acttttcatt ccgattttgt ctttttgatc gatgcagaga aaatccaaca ttttcctgca
    15301 agaaactgga cacatgatca aatcatcgaa gaactgaaaa aacggttcga tcattcgcta
    15361 atggtcaaac cctggcacga acatgaagtc atttattcac ctgaactacc tgtttttgcc
    15421 ttgataccga aaaaatagaa agaatggaac ggattatgta tatatacata atccgttcca
    15481 ttttttattt ttctttcaaa aaacgggaaa atacgcaaat ttttctgttg taatttgcgt
    15541 atacgcaagt ttttttgcat tactcctttt catttggctg tttttttctt ataatcgaaa
    15601 gggtatgagc gaaggagaga acatatgaag aaaaaacaga aacaaaaatt attaaatcaa
    15661 ttccgtcctt cattggatgg tgtaagagga caattattcc gttctctaga agaagagagc
    15721 ttgcgacgct atggtttgcc gttacaagtc atgcttgatc ccaaaaaccg tcaaatctta
    15781 acgatcggat tagctgggaa aacaaatgaa gatacacgga tcaacgtgcc aatcgatgac
    15841 aacttcaata ctgtattaaa gagaattcgt tcaggagaaa acgggatttt cgaacgattc
    15901 cgtgacaatc ttcttattga aatcgtgtct tactggaatg atcaacgatt gaaaaacgat
    15961 gaaccaactg cgcaagctgt tgcgacacca gttacagaag aaacagtcag tgtgccagaa
    16021 gaaaaaacgg aaaaaccaaa agcggacaca actgaaaata cacgctcaac tgatacgaat
    16081 gccgctttaa gttttgctga tttttcaaaa gccgttgctg agtatcctaa attttacaca
    16141 gaacaaaatg aacatgaagt agttattaat gaaaaaaatg ctgatgaacc tcgtaaatta
    16201 gcaactattt ctatgactac tgaaaatgag ttcgttatcg aaaaagcact cgaacggaaa
    16261 tacaaagtca aattgacttt gattcctttg atcgaacaat ttgcagcgac agcgattact
    16321 gatcgataaa aattctattt gtcataaaag gctgggattt aaaatcccag cctttttagt
    16381 catataataa tttctacagc aagtaaaaag aaattccttc taacatcagg ctcaaatatc
    16441 agcttgacct gtccaacaaa tcacctatga tcctacaatg ttaggcgact tctcttctac
    16501 ctgaagatat cttggagttg cctgatttct taagatgcct aaccttaact ataaaaaatt
    16561 cta
//
LOCUS       DACDAF010000065        16355 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.065, whole genome shotgun sequence.
ACCESSION   DACDAF010000065 DACDAF010000000
VERSION     DACDAF010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16355
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.065"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(196..774)
                     /gene="pgsA"
                     /locus_tag="IVZ69_001941"
     CDS             complement(196..774)
                     /gene="pgsA"
                     /locus_tag="IVZ69_001941"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HAP8184017.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(983..1867)
                     /locus_tag="IVZ69_001942"
     CDS             complement(983..1867)
                     /locus_tag="IVZ69_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8184018.1"
                     /translation="MAFETIGEKLRQARLNKKISLDELQQITKIQKRYLEAIDNDDFD
                     QLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQPETVSTSRKAMHQ
                     EESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDTASSLKVEGSVEES
                     SSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITDATKPVTLEFTAVN
                     RVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNATIKANGESVPVNP
                     GENNQSPKNVNLTLQYAE"
     gene            complement(2645..3931)
                     /locus_tag="IVZ69_001943"
     CDS             complement(2645..3931)
                     /locus_tag="IVZ69_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP8184019.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(3924..5192)
                     /locus_tag="IVZ69_001944"
     CDS             complement(3924..5192)
                     /locus_tag="IVZ69_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HAP8184020.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            5444..5905
                     /gene="mscL"
                     /locus_tag="IVZ69_001945"
     CDS             5444..5905
                     /gene="mscL"
                     /locus_tag="IVZ69_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HAP8184021.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(5964..6410)
                     /locus_tag="IVZ69_001946"
     CDS             complement(5964..6410)
                     /locus_tag="IVZ69_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8184022.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(6503..6748)
                     /locus_tag="IVZ69_001947"
     CDS             complement(6503..6748)
                     /locus_tag="IVZ69_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184023.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(6863..7441)
                     /locus_tag="IVZ69_001948"
     CDS             complement(6863..7441)
                     /locus_tag="IVZ69_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP8184024.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(7518..8048)
                     /locus_tag="IVZ69_001949"
     CDS             complement(7518..8048)
                     /locus_tag="IVZ69_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HAP8184025.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(8052..8912)
                     /gene="rlmB"
                     /locus_tag="IVZ69_001950"
     CDS             complement(8052..8912)
                     /gene="rlmB"
                     /locus_tag="IVZ69_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HAP8184026.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(8905..9300)
                     /locus_tag="IVZ69_001951"
     CDS             complement(8905..9300)
                     /locus_tag="IVZ69_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HAP8184027.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(9297..10709)
                     /locus_tag="IVZ69_001952"
     CDS             complement(9297..10709)
                     /locus_tag="IVZ69_001952"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HAP8184028.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(10706..11242)
                     /gene="cysE"
                     /locus_tag="IVZ69_001953"
     CDS             complement(10706..11242)
                     /gene="cysE"
                     /locus_tag="IVZ69_001953"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HAP8184029.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     gene            complement(11564..13024)
                     /locus_tag="IVZ69_001954"
     CDS             complement(11564..13024)
                     /locus_tag="IVZ69_001954"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HAP8184030.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(13194..14351)
                     /locus_tag="IVZ69_001955"
     CDS             complement(13194..14351)
                     /locus_tag="IVZ69_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HAP8184031.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(14385..15755)
                     /gene="radA"
                     /locus_tag="IVZ69_001956"
     CDS             complement(14385..15755)
                     /gene="radA"
                     /locus_tag="IVZ69_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HAP8184032.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(15818..16345)
                     /locus_tag="IVZ69_001957"
     CDS             complement(15818..16345)
                     /locus_tag="IVZ69_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HAP8184033.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         4336 a         3587 c         2936 g         5496 t
ORIGIN      
        1 ttttatttaa aaagagggca aggagctgtg acaaaaatct tgtcacagct ccttgttcca
       61 aataaacagt gttctcctgc caaaacctcg gtcataagtc acaatataca taaaacatga
      121 aaagctgttt tttgaaatta tcccttgtga ctcagagtta gacggcaggc tcacaacctc
      181 tccactaaac gatacttaca ttgatccttt gaacacaccg ctgtttttga tgaagtaatc
      241 cacacctgaa tagatagtaa agatcagaca agcataaagc atgatttgat ctactggaat
      301 accgatcagg ctgaatggga tattattgat aaacagcaag ataatagcaa ccatttgtgt
      361 agccgtcttg acttttcccg gccaagctgc agccatgact tctccatgtt cgacaagtag
      421 taaacgcaag cctgtgacgg ctaattcacg acagacaatg atcgctacta cccaaccagg
      481 ggcctttcct tggtcaacca acatgataaa agcagtcata actagcattt tatctgccaa
      541 cgggtccgca aacttgccaa aattagtgac aaggcctcgc gcacgggcaa tttttccatc
      601 taaccagtct gtgatactag ctaaagcaaa aataactgca cctactagct gtgtgacagc
      661 cagtgtggtg tctcctacgt taaattgtcc ccaatctaaa ggtaaaccta caaccaaaat
      721 gaaaatcggg atcatacaaa ttctaagtac agttaattta tttggtaaat tcacactatc
      781 gactcctttc ttccctattc tacgtgacta tcagcgaagt ttccaccgat attatttact
      841 tttccaaatg aatttattca aaggagtatt tttattgaaa ttgatctttt tgaattaacg
      901 aagaaggacc gcgacacaga tttgtcacga tccttctttt ttatacctac aagtaaacag
      961 atgcgtaaac taatttatac gatcattctg cgtattgaag agtaaggttc acattttttg
     1021 gactctgatt gttttcccct ggattaactg gtacggattc tccattcgct ttgatcgttg
     1081 cattgcttgc tgcaccaatc gtgatggtcg catttgttgc tgtttccggt aacacggtac
     1141 tctgtgtttc atttgctgcc agtgtccctt gataaacata ggcattgtct actagcacac
     1201 ctaaccatac acgattgaca gcagtaaatt caagggttac aggcttggta gcgtctgtga
     1261 tatttactgc gatggcactg ccagaatctt ctcctgtagc tattgccatt ttcttttctt
     1321 cacttgattt tgttgttgat tctactgtag aagactcttt ggtctgcgtg ctttgctctg
     1381 aggaagagga ctcctcgact gatccttcta ctttaagcga agaagctgtg tctccgatta
     1441 ttggatcagc ttgacgatct tgccaagtca tatagcccac gacaacgaca atcgccaaag
     1501 caaccaatcc taataaaatg acaggaagac ttgtccaaaa gcgacttgga tgcgattctt
     1561 cctgatgcat tgcttttcta gaagtactta ctgtttcagg ctgcggacgt tcagggaccg
     1621 atcctgtcaa tttgcttttc ccatcaaaaa catcgactaa atggtctcca tcttctccta
     1681 cagcttcagc gtattgccga ataaatgccc gcacgtaaaa tttaccaggc aattggtcaa
     1741 aatcatcatt gtcgattgct tccaaataac gtttttgaat ttttgtaatc tgctgtaatt
     1801 catctaaaga tattttttta ttcaggcgtg cttgccgtaa tttttctccg atggtttcaa
     1861 aagccactcg ttcatcttct ccagtctgtt tgattctccg aagcatctgc tgttgcaacg
     1921 aaagacgtta tgtttgggtg ctgtgacaaa agtcatgtca cagctccttt tttccgaata
     1981 aacattgttc tcctgccaac tcctcggtca caagtcacaa tatccaataa atataagaag
     2041 ctgttttttg aacttgttcc ttgtgactcg gagttaaacg gcaggctcac gacctctttc
     2101 ttaaacggtg ttcaatcagc tgttcctcgg tattagctca aaaaccggca aaatataagg
     2161 agatattttt ccgtatgttt ctctaatact caggtcaaaa cgctgatttc acaacctctt
     2221 ccttaaacgg tgttcaaaag cttgcatctg cggtaataag tccaaccaag ttaaaaacat
     2281 taagaagctg tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac
     2341 ctcttggtac acggtgttcc agaagtagct tcttcggcaa taagccgaaa tatcacaaaa
     2401 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
     2461 aacctctttg attacttcgt ttgattttat tttaatataa gttgattaaa agagagcatg
     2521 atttgtttta ttttctcact aatttttcca acacaactaa gaataccata aaagctgatt
     2581 ttggaggagg ttcctactac aagtctaaaa cgaaatttaa gacttttcct cataaaatac
     2641 tggtttattt tggtctcatg taaaactcgc tgaaggcctc ttcacttata aatgcttccc
     2701 cagctgccag tacgtctttc atttggatcg aatcgatgat ttcaggaaga tcaaataaag
     2761 ttcgatcgcc aaataaactt tgcgtaaatt gattggcaat atattcgatc gaatttaatg
     2821 attggaaata ttgtccaagc attttcttct tcagcaaatc gagatttgtt tctgacactt
     2881 ccggatcatc agcgaatcca agaatgattt ctttgacttt ttctgctgct ttctctggtt
     2941 cgtccgtatc tccgctgaag tccgcaaagt gaaattcacg atccaagctg aattcaaaac
     3001 caaagctgtc atcgataatt ccttgattgt acatcgctag atagtttcga gaagtattgc
     3061 ctaaaatcat ttggaacaac agattgattg ctgttttata gcgtaacagt tctgttcctt
     3121 cttgcggcaa tgtgtctaat cctttaatac caagtacaaa tttatctcgt gtaatggctg
     3181 cttccaatgc actttgtttg atgatttctt ttgtgttttc agggaaataa cgtacaattt
     3241 cttgctttgg agggaaattt tttgcttctt ggttttcccg aataagtttc atcaatttct
     3301 caggctccat cttaccaact acaaataaaa ccatattgct tggctgataa aacgtccgat
     3361 agcacgtata caagtcttga gctgtgattt tgtcgatact ttcaaccgtg cccgcaatat
     3421 cgatatgcaa tgggtgtgta ggatacaagt tatttagtat gccaaaaaac atccgccagt
     3481 tagggtcgtc ttcatacatt tggatttcct gaccgatgat tcctttttcc ttgtttacag
     3541 tttcttctgt gaagtaaggt gcttgtacaa aatcgatcag agtcgtcaga ttcttttcta
     3601 cctgatccgt cgtagaaaac agatagctgg ttttcgtaaa acttgtgaaa gcattggcgg
     3661 aagctccttg tttcccaaat aattgaaaga catcaccatc ttctttttca aacaacttat
     3721 gttctaaaaa atgggcaatt ccatctggaa ctttcacctt ttctttttca ccatagggaa
     3781 taaattcgtt atcgatcgaa ccataattcg tactgaacaa accatatgtc ttgtgatagt
     3841 catttttagg caacaaatac acggtcaaac cgtttggcag tacttcatga taaagtgttt
     3901 cattgatttg ctcatattct gttttattca tttgcatttc ctcctgctaa aaagaagatt
     3961 gcctgcaatt cgatttgctc agctacttgt tgtatctctt tgatcgttac gctctccata
     4021 cgtttcaacc attcttcatc agataatttt gtttccggca gccagctgtc caaaaaagaa
     4081 gcttcgattg ccgcttgcgg agagtctaga gaaagcagat attggtttct cagcattgct
     4141 tttgtctgag acagttccaa ctctgttatt tcaccatttc gcaaactttc taattgctcg
     4201 tgaatcagat gaagtacttg atttcggttc ttttcatcga taccggtttg gacactcatg
     4261 aatcctcgga acgtatccac gctactagag gcataataag ctagactttc tttctctctg
     4321 acattcatga aaagtttaga gtgaggaaaa ccgccaaata aaccgttaaa gaccattagc
     4381 gcaaaacgtt ctggttcatc gtaatacaca tttgtctgat aagctaggtt cagctttgct
     4441 tgaacgattg gctcacgtac ttgtcgttcc ttcacgatat tcacttgagg ttgggtataa
     4501 aacagatctg gataaactgt ttcccgcgac tcaaatggta attgcccaac tgcttcagct
     4561 gctttgtccg gatcaacatc gccgacaaca aaaatgtcga tttgatcatt tgccatcatt
     4621 tcttgatagt aggacgctag cgaactagca gtgatcttgt ccaaatcttc gactacgccc
     4681 aaccctggga tcttttgttc cgggctgttt tcaaaataaa gttcttgcaa ggcataggaa
     4741 gcaaaagttt gtttatcttc cttcaaactt tccaaatata gacgcagatt gttcttttcc
     4801 aagtcaaacg tcaactgatc aaactgatga tttttaatat ttggataaaa taaaacctct
     4861 tttaaaaaat ctaccgcttg agaaaaaagg tttggatcat tgacatattc accattcaca
     4921 aaactgatcc ctgcgtttag ccaatgtaaa tttccttttt ttctaactga taatccaaag
     4981 cttgcgccat aaagctctgc aagttgcgca cttaactttg tctgatccgg ataattcaaa
     5041 ctatttgttt ccaacatgct gctgagaagt gaacgtttcg tgatgacttc ttgttgcaga
     5101 cgcgcagtaa aacggataaa aatccggatc gttttgtatt gttttgttgg taagacatga
     5161 agattcacgc cttctgccaa ttgatacacc atatttatat gctccttttc acagttgatt
     5221 gcccgcttac tcttttaatg ggtcaacctg ccttttttac ttattcctct gcttgaaatt
     5281 tataagttca ggcaattcgc cgttttttct aaatgatgtt acactttata gtatagcata
     5341 gatgtttttt atcaaaagaa acagacggct aaaagcgtat attgtttttt tattttttat
     5401 ttttcgatat actaaagaca aataaaagaa gggagggtca ttcatgatca aagaattcaa
     5461 agagttcatc atgcgtggag atgtcttgga tcttgctgtc ggcgttgtta ttggtagtgc
     5521 gtttacaagc atcgtaaacc aagtggtgca aggcttgatc acaccactaa taggttggtt
     5581 tgtcgcaatg atcacaggta cttctgattt agaaggagca ctttcaattc ttgactggtc
     5641 gccgacaaaa ggcgtcacat ttgcgtttgg taacgttatt agtgctatca ttacatttct
     5701 gatcactggt tttgtcttat tcttagttgt caaagcggca aaccgtgcga agaatttacg
     5761 ctccaaagaa gagcaagtgg aagtggaaga aactcctact gcagaagatt atcttagtga
     5821 catacgcgat cttcttgcca aacaagtggc agaagacaat acacatccag tagagcaaac
     5881 aaatctttcc gatacttcta aataataaag aatctaaaaa aaagaaagcc gattttcagt
     5941 gtcggctttc tttttttaga ttcttaactt gctacttgtt cctttttcat gtcgatatgt
     6001 ggaatatcat cttccaaata cacatctgag attgccttga atccaaacga ctcataaaaa
     6061 gcttgtaggt attcttgtgc gccgatcacg attggttttt ctggaaaatt tttctggatc
     6121 atgttaatcg tttcttgaac aatctttctt cctaaaccat ctttacggtt gtcctgatga
     6181 acaaggacac gtccaaaatg gatactctcc gcttcttcat atactcgcgt gtaggcaagg
     6241 atcttcccat cagtatcttg aaaaaacgta tgccaagctt gtccatcaat gtcatcaact
     6301 tcttgataag gacactgttg ttccacaaca aaaactgcga ttcgttcttt gacgatcgcg
     6361 taaaactctg ctgttgacaa ttcttcaaat ttctttacct gatattccac taagcaaacg
     6421 ccccctgctt ttttattctt agcataccga ttcgcacaca aaaaagcaaa cgaaccttac
     6481 gaatctcagg ctcgtttgct ttttaaactg cttcagttaa aaattcgatc tcaactgtcc
     6541 gagtaagtac atctgaatag ctgtaagata ctcgttcaaa agaattttct tcaggatcca
     6601 aatcaacaac gaatactgaa ggataggttt ctgttaaaac gccgcggcgt tctgtttgac
     6661 gctttcttcc tgtctgagca accaacatga ttgggctgcc gatacgacct tctaaatctt
     6721 tcttgattga agctaaagtt gttggcatac agttcacctc tactatcaac tataccacat
     6781 atttttaaaa ttttcaagtt taccataaaa aaaaaagaaa tgcaataaaa ataaataaga
     6841 agctcattaa gatttttcta aattattcct cattataaaa tttcaagtgt ttttttattt
     6901 tgagttttac tctcccgtaa gcgctcatta cttgcttgtg atccattgct aaacattcag
     6961 ccatgtctac aaaatcaacg ccttgcatat aataatgaaa aattttagct tctatttttg
     7021 aaaactggat ttcgcaattt tcgattgctt cttttaataa aagatgctga atcgctaaag
     7081 gttcttgcaa tgtgatctct gctaaaaagt ctggtccttc tgtctctatt ttttggtcga
     7141 ttgagacttc atctttttga tcacgacgct tcagcgcgtt ctgcttcctc aacagagaat
     7201 agatttgatt gcttataatg cttttataat aacttccaaa gctaacacct ttgctttttt
     7261 cgtaagttct caatgcctga tataaagcga tccttgcttc ttgttcccaa tcctcagaaa
     7321 cataatttct taaataatag gtgtttttca aacgtagtaa aagtggaaaa tatttttgat
     7381 acagggcagc aaatgcttct tcgtcaccat tacgtgcagc gcgcaataac tcctcagaca
     7441 taaaataatt cctccataaa ttcgtttatg gaggaatctt atcatcaatg attcatcgaa
     7501 ctgattagaa cgatatgtta tttatttttt ctcattaaat cgtccaattt ttgggacaat
     7561 ttttttaact gctcttcatt ccatggagaa ttacgtcgga aatcaataaa atgcatatct
     7621 ttattttctt gggctattgt tttttccgtt ttttttatcg tcttatataa ttcataagca
     7681 gaagttcgta atgctccttg ggaaaagatc atccactgtt ctgctaaatc gcttgtcgcc
     7741 actgtcactt gtgtcaaacg gtcattcagc tgaccagcga ttctctcgat ataactgtca
     7801 gccgtttcgt cttctttcgt aaaaacaaca tccaactggt atttcttata attttgttgg
     7861 atgcccggaa ctagttgggc atcgaagaca acgatgactt ccattccttc atatttcgca
     7921 taatttgata aacgatgtaa aagagcttct cttgcatccg ccattttgtc ctgcttttta
     7981 agctggacaa gttccggcca cgaaccaatc atgttgtagc cgtctacaat caacagctgt
     8041 tttttcatgg tctactcccc ctgacgttgg gaaaaagcct gatacataag caaaccagca
     8101 gcaacactgg catttaagct ctggacgtgc ccggtcatcg ggatcgtcag caattcatcc
     8161 atttcttttt tcaatcctgg actcattcct ttgccttcat taccaatgac taaagcaatt
     8221 gatcctttgg cattccattt ttggaagttt gtgccggtca tatctgtgcc aaatacccaa
     8281 aatcctgttt ctttgagctg ttgcacagct tgtaccaaat tcgtcacgcg tgcaacaggg
     8341 acatgttcga ctgccccagt ggaagtcttt gttacgatag gtgtgattcc aactgctcgg
     8401 tgttttggta tgatcacacc atcgacgcca cttgcgtctg ctgtccgtaa aatcgaccca
     8461 aaattgtgtg gatcttcgat gctatccaaa atcaaaaaga aggggtcttc ttttttctct
     8521 tttgttcgtt caatcagttg gtcaagggat aaatattcat aaggtgtaat cgcaagaacg
     8581 actccttgat gcacgccgtg atcgctcaaa gtttctaatt tttgtttagg aacccatttg
     8641 actggcacag cttgttcacg tgcgatttct ttcagttctt ctactttttc tcctcgtgaa
     8701 tcttcttgaa gaaagagttt attccctcgc ccttgttgta gcgcttctac tgcggcatgg
     8761 tgcccaaaga cgaaattatc ttctaatgct tcttcatttt gatcagaaac tgactgattt
     8821 cgtccagttt gctttttatt tgaatatcta ttttgttttt tgtcttcaaa tccacgtttc
     8881 gattgatgtt tgtttgttct ttctttaccc atttttttca ccaactttct gaatacacca
     8941 gcggatcaat tcttccatcc gctcggtttg ttttgtcaaa tgcagatagc ccatgagcgc
     9001 ttcgaaccct gttgcgaccc gatacgtcgt aacatcagca ttttttgcgc tcgtatggct
     9061 tttagcattt cttcctctgc gataataaag ttcttcttct tctgtcaaaa gatgttcttc
     9121 cagcatttgc tgaatcaaaa aggcttgtgc attcgcagaa acataattcg ttgccgcacg
     9181 atgcagctta ttgggttttg tttctccttg atcaatcagg tggtcacgaa catagatttc
     9241 gtaaatcgca tctccaacat aagccaaggc taaaccgttc aattgtgtgt aatctctcat
     9301 gcttctcttc tccatcgggt tccttgcggt gtatcttcta ataagatccc tttttctttc
     9361 aacaaatcac gaatttcgtc gcttcggaca aaatcacgat tgcttcttgc ttgatttcgt
     9421 tcttcgatca attgttcaat ctcttcatct aataactctt ctgctgtaaa taaaataccg
     9481 aagatcgaaa gccattgcga gaataaagct tctccttgtg ccaagacagc ggcagaaact
     9541 ttcggctggt ctagataagt gttcagccac ttagcaagct catagaccac tgtgatccca
     9601 tttgctgcat taaaatcatc gtccatttct tcgatgaatc gctgttctaa attttctaac
     9661 aaagcgattt tatccgcatc atctgccaaa ttctctgagg cagtttcttg gcggaatttc
     9721 aaattgtcaa acgtattctt cagtcgttgt aaattggtgg ctgcttcttt catcgtcgtt
     9781 tcactgtagc ggatcggacg acggtattgt gtggtcgcca tgaagaaacg caagacttgt
     9841 ggatcaacgt ttttgatcat ttcatgtaca gtgatgaaat tccctagaga tttactcatt
     9901 ttttcatcgt cttcgccaat cgttacatag ccattgtgca tccagtaatt agcgaatttt
     9961 ttccctgttt tcgcttcact ttgtgcgatt tcattttcat gatgaggaaa ttctaaatct
    10021 tgcccgccac catggatatc gatcgtttct cctaaatgtt ttgttgccat aacggaacat
    10081 tcaatatgcc aaccgggacg tcctttgccc catggtgaat cccaagaaat ctcgccaggt
    10141 tttgcttgtt tccataaagc gaaatctaat gggtcttctt tttgctgctg ttcttcccct
    10201 gtacgctgac ttgctccgac ttccagttca tcgatggatt ggtcacttaa tttcccataa
    10261 ttttcaaatt tacgggtacg gtaatacaca tcacctgaag attcataagc atagcctttt
    10321 tcaaccaaca cttgaataaa tgctaaaata tctggcatat gatccatgac tcttggatgc
    10381 agtgtagcag gctcgacatt caacgctttc gtatcttctt caaatgctcg gatgaaacga
    10441 tcagcaactt ctggtgctgt aatacctaat tcgtttgctg tacggatgat tttatcgtct
    10501 acatccgtga aattcgatac gaaatcgact ttatagcctc gatattcaaa atagcgtcga
    10561 attgtatcga aagcaatggt gctacgagca tttccgatat ggatataatt atacacagtc
    10621 ggtccgcaga catacatacc gacatgtccc ttttgtatag ggatgaattc ttcttttttt
    10681 ctggtcaatg tattgtagat ttttatcatt ctgatctcct cactttttct cctttgattc
    10741 gaacgacttt tgctggtact cctaccgctg tagcgtcgtc tggaacatct ttcaacacaa
    10801 cggcacctgc accgattttg gcgttttttc cgatcgttac cggtcctaat atctgcgcat
    10861 tcgcagagag catggctcct tgtttaacag ttgggtgtct tttacccgtt tcttttcctg
    10921 tgccgcctaa tgttacgcca tggaataaaa tcacatcgtc ctcgatttct gcggtttcgc
    10981 caatgacgat tcccattcca tggtcgatga acacgccagt tccaatcgtt gctcctggat
    11041 ggatctcaac accagttagg aaacgccaga attgagcatt gatcttcgcc aataaaaaga
    11101 gccggtgctg atataaaaaa tgagagaaac gatgccaaaa caaggcatga aaaccagggt
    11161 atgtcaaaac gatctcagct gtcgaacgtg cagccggatc gtttctcttt gctgcatcaa
    11221 tcgctcgggt aaaccaactc atgactttcc actcctttcg taagaatttt atgtaggaaa
    11281 tcatcttctt ataaagaaaa gaagcgcctt ttaaataagt ttccttatca aaagacgctt
    11341 tccgcgtggt tccacttttc ttcataatca atgattatct ctgacagcta acgcctgtta
    11401 tacgttcttg gctactttgt ttcctataaa acagtttttc ctgttttctg tgtttcgcca
    11461 agaccactcc cagaggcatt tcggcaacca ttcattgata ccttgcacca cccggtatct
    11521 ctcttgtaat gatcagctgc ttactttttt ctgttcatcg tgtttagttc agtacttgat
    11581 ttaaatgtgc taatgatttt tcacgaccaa gcaattcgat cgtttcaggc aattctggac
    11641 catgcatttg tcctgataca gctacacgga ttggcatgaa aagatttttt ccttttacgc
    11701 cagtttcttt ttgaacagct ttgatggcag ctttgacagt tggagcatct actacttcca
    11761 tttgttctag ctgtgctttg aatgcgtgga gaacagtagg aactgtttca ccagcaagta
    11821 cttcttttgc tgcttcattc aatacaggat gttcattgaa aaatagcgta gacagatcaa
    11881 cgatttctgc agcatagctc atttgaggtt gatacaggct aacgatcttc ttcacccatt
    11941 cgattgtctt ttcatctggg ttttctgcta cacgtccatc agcgattaga taaggcagac
    12001 acatgtcagt aaatgcatct agatccattg ctttgatgta atggttgttt acccattgca
    12061 gttttttcgc atcgaaagct gcgggtgatt tacttaggcg ttttggatcg aacattttga
    12121 tcaattcttg gtgttcgaag atttcgtctt cgcccacagg tgaccagccc aataatgcaa
    12181 taaagttgaa cattgcatct ggtagatagc ctaattcgcg atattgttcg ataaattgca
    12241 agattgattc gtcacgtttg cttagttttt tacctgtttc actgttgatg atcaatgtca
    12301 tatgtccgaa ggttggtggt gtccagccaa atgcttcata gatcatcagt tgttttggtg
    12361 tattggcaat atggtcatct ccacgtaaaa cgtgagtgat tttcatcaaa tgatcatcga
    12421 ccgcaacagc aaaattataa gttggcatac catcgcgttt ttgtatgaca aagtcgccac
    12481 cgatattatc ggattcgaac gaaatagcgc ctttcaccat atctgtaaat gcgtattctg
    12541 tattgcgagg cacacggaaa cgtacaacag attctagacc ttgtgcttct ttttctgctt
    12601 gttcttcagg tgtcaagttc gcacatgttc ctgcgtaatg aggcatttct cctcttgcgc
    12661 gttgtgcttc ccgttctgct tctaattctt cttctgtgca atagcatttg tatgctcgat
    12721 tgctagcaag cagctgatca atcagcggtt gatagatttc tttacgttca gattgacggt
    12781 aagggccgta ttctccagga ttttcaggag attcatccca attcattccc aaccaagcaa
    12841 ggttttccaa ctggcttttt tcgccatctt cgatattacg tttttggtca gtatcctcaa
    12901 tacgaataat aaagtctcca tcattgtggc gggcaaacaa ataattgaat aatgcagttc
    12961 ttgcatttcc aatatgcagg tgcccagttg gacttggtgc atagcgtacg cgtactttcg
    13021 tcattttctt cctcttcttt caaactagac tttgactaac agcaaaaatt ccgtcagtta
    13081 cggcttctca aatatcattt atttaaagcc actcagcaca aattttacct tttctaaggt
    13141 aaatagtaaa gccaactggt tgaatttcct taccagttgg ctgaatttct tttttatttt
    13201 gattgtttag tctttttctc tgtctctttt ttattgtcga ttcctcgtcc tgcatgtgca
    13261 ggtttagcaa agatcatgcg tccagcagct gtttgaaggg cacttgttac aacgacttcg
    13321 atacgttcat tcatgtaatg ctgtccatct tctacgacaa ccatcgtgcc gtcatcaagg
    13381 taggctactc cttgttggcg ttctgtcccg gcttttacta ctagaacatt catcgtttca
    13441 ccagggatga cgactggttt tacggcattt gccaacgcat tgatattaag aacaggtaca
    13501 ttttggaatt cagagacttt attcaagtta tagtcattgg ttacaatgac accatctaaa
    13561 agcttagcca atttgatcaa tttgctgtct acttcactga tatcttcaaa gtctccatcg
    13621 tacatttcga cagatatacc ctcttctttt tgcaaggcat ttaggatatc taatccgcga
    13681 cgaccacgca cacgtttcaa actatcccct gagtccgcga tgtattgtag ttcgtaaaga
    13741 acaaaattag ggatcatcaa ggttccttct aagaatccag tctttgtaat atcataaatc
    13801 cgaccgtcaa tgatcacgct tgtatccaag attttatatt tatggaaatt ttctcctgat
    13861 tttcgttcta acagttgact ctcaacttga ctagctgttt cttgctcgat ttttttgctt
    13921 cgtgaaccaa aaactttctt ccattcttcg attcgtgtcg ttcccattct caatcccaga
    13981 tagcctaaga tgatcatcag taaaatcggc aatacactat tgacgaatgg aatttccata
    14041 ttgtaaagag gggtcgagat cacaacacct aaagtcaatc cgatgatcgc accgatcgca
    14101 ccgaagagaa gataagtcaa gctgacctca cttagttttt gttctacttg tttgataata
    14161 gctgagatat gtttggccaa cagcaaagat aataaaaaga aaataagtgc gcctaacagg
    14221 ctgttggtaa atgtattatt cagccatccg tttgactgtt gaccgattgc ctgccaagct
    14281 gagggtaaaa atgaaatacc caagcttgcg ccgacaatga tcatcagcaa agtaatgaca
    14341 cgtttttgca tcgtttttcc tccgtttcga caatcattta ttagttagcg gaacacacgc
    14401 ttcaacgttt cagccaaagt tgctactcca actatctcga ttccttttgg cgcttcccag
    14461 ttacctaagt tgtttttagg taggtatact tttgtgaagc cgagtttttg gacttctttg
    14521 actcgttgtt caatatgact gacacgtctg atttctccag tcagtccaat ttcaccgatg
    14581 aaacattccg ttggctgtgt tcctttttct ttatagcttg aagcaatact gacagcgata
    14641 gctaaatcaa tcgctggttc atttaatttt accccacctg cagcttttaa gtaagcatct
    14701 tgattctgaa gaagcaaccc agctcttttt tccagcactg ccatgatcag agatacccga
    14761 ttgaaatcaa gacctgttgt tgttcgtttg gcatttccga acatagtagg tgtgactaat
    14821 gcttggatct ctaccaaaat tggacgtgtc ccttccattg ccacaacgat agcagagcca
    14881 gttgcaccgt ctaggcgttc ttctaagaaa atctgtgaag gattagcgac ttcttccaat
    14941 ccatgctcat gcatttcaaa aatcccaatc tcattcgttg agccaaatcg gttttttact
    15001 gctcgcaaaa tccgaaaact atgatgttgt tcaccttcaa aatataacac cgtatccacc
    15061 atatgttcta acattcttgg gccggcgatc gagccttctt tggtaacatg accgacgata
    15121 aaaatggcta tcccatttgt tttagcgatt ttgagtagtt ctgcagtggt ttctcttact
    15181 tggctgacac ttcctgccac acttgtgatg tctggctgcg tcatcgtttg gatggaatca
    15241 atgataacat aatcagggga gatatgttcg atggcacgac tgatttcgtt catatctgtt
    15301 tcagcgtata gataaaattc tgtgttgata cttccgaggc gttccgcgcg taattttatc
    15361 tgctctgcgc tttcttcgcc ggatacatat aagacttttc cgcctatggc tgctaattgc
    15421 tgagaaactt gtaacagcaa agtggatttc ccgatacctg gatcgccacc aatcaagacc
    15481 atagaccctg gcaccacacc tccgcctaac acacggttca gttcttctaa ttttgttttg
    15541 atccgaggtt cttttttagg gacgacgtct gcgatttttg ttggttttgc tttttctcct
    15601 gtcaaacttg tccgagttct gcggtccgtt gtatcttgtt cgatttcttc gaccatcgta
    15661 ttccattttc cgcaatttgg gcagcgtccc aagaacttag gcgacacata cccgcaattt
    15721 tggcaaacaa attgtacttt tgattttttt gccattgtac cgcctccttt tatcctaatc
    15781 atgagacatt aaatcaagct taagtatctt taacgtttta tttactggaa gaaccaaatc
    15841 cgccttgacg ttgagcagtc gtttgatctt gatctgcttt taaaaacggc aaaaagatcc
    15901 cttggccgat acgctcgcct tttttgatca ctacatcctt gaaaccaaag ttggtgaatt
    15961 ggaacatgat atggccttca tttgcctcat tattgtaata atcactgtca atcacaccta
    16021 ctccgtttgt caacactaaa aaccgcttca acggattgct tgaacggtta gcaagctgca
    16081 aaaattcatc ttctcccatg taagctttga ttccagtagg cacgagggtt ggtttcaatt
    16141 gtttttcatt ttctgataca tcttttttca atccatctgc gactgtttcc aacccctttt
    16201 tccagcctgc tttccagata cttggaatca cgacctcttc tgctgcttca aaatcatagc
    16261 cagcagcatg atgtgtagcg cgctgcggta gattgatatt ttgatcttta tatttagaaa
    16321 taacttcaaa tcctcttttt ctcaccggtt ttcct
//
LOCUS       DACDAF010000066        15936 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.066, whole genome shotgun sequence.
ACCESSION   DACDAF010000066 DACDAF010000000
VERSION     DACDAF010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15936
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.066"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(15..1154)
                     /locus_tag="IVZ69_001958"
     CDS             complement(15..1154)
                     /locus_tag="IVZ69_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HAP8184034.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(1553..2851)
                     /gene="eno"
                     /locus_tag="IVZ69_001959"
     CDS             complement(1553..2851)
                     /gene="eno"
                     /locus_tag="IVZ69_001959"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HAP8184035.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            complement(2967..3722)
                     /locus_tag="IVZ69_001960"
     CDS             complement(2967..3722)
                     /locus_tag="IVZ69_001960"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HAP8184036.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            complement(3826..5016)
                     /locus_tag="IVZ69_001961"
     CDS             complement(3826..5016)
                     /locus_tag="IVZ69_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HAP8184037.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            complement(5126..6127)
                     /gene="gap"
                     /locus_tag="IVZ69_001962"
     CDS             complement(5126..6127)
                     /gene="gap"
                     /locus_tag="IVZ69_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP8184038.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            complement(6168..7205)
                     /locus_tag="IVZ69_001963"
     CDS             complement(6168..7205)
                     /locus_tag="IVZ69_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SorC family transcriptional regulator"
                     /protein_id="HAP8184039.1"
                     /translation="MLDEIKMIESVAPDIIEVLQERYKILRNIYWMQPIGRRSLSESM
                     GITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSLENFMDQLLGTHQTEQQLA
                     EYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEGENIIAVMGGTTMAVVAEQ
                     LSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKANGNHRALYVPEQLSLATYN
                     SLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEKELVMLKQANAVAESFGYF
                     FNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAIRAYMKNAPKQTWLITDEA
                     AANEILKGVTL"
     gene            complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="IVZ69_001964"
     CDS             complement(7408..8742)
                     /gene="rpoN"
                     /locus_tag="IVZ69_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HAP8184040.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            8802..8873
                     /locus_tag="IVZ69_001965"
     tRNA            8802..8873
                     /locus_tag="IVZ69_001965"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:8835..8837,aa:Arg,seq:ccg)
     gene            complement(9065..9949)
                     /locus_tag="IVZ69_001966"
     CDS             complement(9065..9949)
                     /locus_tag="IVZ69_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HAP8184041.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNYTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(10036..10935)
                     /locus_tag="IVZ69_001967"
     CDS             complement(10036..10935)
                     /locus_tag="IVZ69_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 and DUF4163 domain-containing protein"
                     /protein_id="HAP8184042.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            complement(10952..11458)
                     /locus_tag="IVZ69_001968"
     CDS             complement(10952..11458)
                     /locus_tag="IVZ69_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HAP8184043.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            complement(11647..12267)
                     /locus_tag="IVZ69_001969"
     CDS             complement(11647..12267)
                     /locus_tag="IVZ69_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HAP8184044.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            complement(12343..12780)
                     /locus_tag="IVZ69_001970"
     CDS             complement(12343..12780)
                     /locus_tag="IVZ69_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HAP8184045.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTGGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            12943..13773
                     /locus_tag="IVZ69_001971"
     CDS             12943..13773
                     /locus_tag="IVZ69_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HAP8184046.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            13757..15124
                     /locus_tag="IVZ69_001972"
     CDS             13757..15124
                     /locus_tag="IVZ69_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HAP8184047.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            15143..>15936
                     /gene="yidA"
                     /locus_tag="IVZ69_001973"
     CDS             15143..>15936
                     /gene="yidA"
                     /locus_tag="IVZ69_001973"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HAP8184048.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAI"
BASE COUNT         4310 a         3333 c         2938 g         5355 t
ORIGIN      
        1 ttattaaaaa aatcttacgc taagtaggat aaaataattc cttgatattt ttcgatcata
       61 tccaaataat tatcgatttc aacatactca tctacttgat gaggcaaagt aacgacacca
      121 ggcccaaaga cgacaaagtc gaaggaatgg ttagctttcg taaattcggc tgcatccgtt
      181 gttgctgccg ctccaactaa aggtaatggc tggctgaatt gttgctgaat gcaatgaatc
      241 aaaggagaat ctggatcagc tttgacaggt attttgttgt aatcgatcat caattccaaa
      301 tgatagtctg tctcttgatt caattcattg acgattgatt gcagcaatgc aatgatttta
      361 tcatttgggt attctggaat cgatcgaatg ttcccttgga gctgcgcatg gcttgggatg
      421 ctgttgactt gattcccgcc actgatcaat gtaacattat ggattgtttt tcctaggaca
      481 ggattctcga ttgtttcagc gaggtgattc atttcagcat ttgctttcgt aatgaattca
      541 tttaggtgat tgattgcatt ataaccttgg tctggcatag agctatgcgc ttcttttccg
      601 tgcgaggtga ctgtatagtt gattgatccc atgtgcgtat acatcaaact gtaattggtt
      661 ggctctccga tgatcaaggc atctaagtca tctacatagc ctgctttcgt gagctgttcc
      721 ccacctagtt cacccacttc ttctccgaca gtggctaata atttgactgt tccgttaaat
      781 ggttttcctg actctttcag ttcgatcatg gcaatcacca ttgctgccaa gccactcttc
      841 atatctgtag caccacgtcc gtacaaacgg ttcccatgga tttctgctgc aaagggtgca
      901 taggtccaag acgattcatc accagccgcc acgacatcca tatgtccaga taggcctaac
      961 acttttcctg attggccctt ttggtaacga gcaatcaaat tatctctacc atctctgtaa
     1021 gaaacaatct ctcctgttat gtcatgcttt gccaaaagct tattcaaata ggctgctact
     1081 tcaccttcgt ttccattcac tgatttaatt cggataatct cttgtaaaat cgcgattttt
     1141 tcttcttttt tcatctaatc ctctcccttg ccatttcttt ttattgtatt tgagtgtgct
     1201 cgaattttca aataggagca accaaagtaa aaatgaagaa agagagccac tttatgaaaa
     1261 atatgctgct acttccctcc tattttattt atacgagagg acttgcccat agattcctat
     1321 tctactgttc tatccttaaa agctcttata tgatgctagt tattgttagc tttccttttt
     1381 caaggatgat cttttcttgt accattcttt gtaaacatca tatacagaag ctagttgcaa
     1441 aaaaactctc tacctgctga tatttcagca agtagagagt tcgattactt aactaagtga
     1501 tcatactcga ctatctttca atagtcgatc atgtatcttc attagaaaag aattatttgt
     1561 tttttaagtt gtagaaagat ttcaaacctt tgtattctgc aacttcacca agttggtctt
     1621 cgatacgtag taattggttg tatttagcaa tacggtcagt acgtgataga gaaccagttt
     1681 tgatttggcc agcgtttgtt gcaacagcga tatcagagat tgttgaatct tctgtttcac
     1741 cagaacggtg agatacaact gctgtgtagc cagcttcttt agccatttcg atagcttcga
     1801 aagtttctgt taatgtaccg atttggttca ctttgataag gattgagtta gcaattcctt
     1861 tttcgatacc ttcagataat ttttgagtgt ttgttacgaa caagtcgtca ccaactaatt
     1921 gaactttgtc gcctaatacg tcagttaatt tcttgaatcc gtcccagtcg ttttcgtcta
     1981 atccatcttc gattgagatg attggatatt tagaaactaa ttcttcgtag aatttgatca
     2041 tttcgtcagt tgttttttcg ccttcgcctg agtcagctag tacgtaaaca cctttttctt
     2101 tgtcgtagaa ttctgaagaa gcagcatcca tagcaagaac aacgtcttta ccaggtacat
     2161 agccagcttt ttcgattgct tcgatgatta cttcaaaacc ttcttcgttt gaaccaaggt
     2221 ttggagcaaa tccaccttcg tcaccaacag aagttgctaa tccgcgagct ttcaagattg
     2281 aagctaatgc gtggaatact tcagcaccca tacgtagagc ttctttgaat gttggagcgc
     2341 caacaggcat gatcatgaat tcttggaagt cgattgagtt atcagcatgt gatccgccgt
     2401 tgatgatgtt catcattggt gttggcaata cttttgtgtt gaatccgcct aggtagtggt
     2461 ataaaggtac ttctaggtag tcagcagctg cacgtgcaac agcgatagaa acacctaaaa
     2521 tagcgttcgc acctaattta cctttgttag gagttccgtc taaagcgatc atagctttgt
     2581 cgatagccat ttggtcacga acatcgtagc caatgattgc ttcagcaatg atgttgttta
     2641 cgttgtcgac agctttagtt acacctttac cgccataacg agctttgtct ccgtcacgta
     2701 attcaactgc ttcgtattca ccagttgaag cacctgaagg aaccattccg cggccaaaag
     2761 ctccgctttc tgtgtatact tctacttcga ttgttgggtt accacgtgag tctaagatct
     2821 cgcgagcgta aacatcagta ataattgaca tgttttgtct ctcctttgag tttgtttttt
     2881 cctaagggat ttccctcata tacgatttta gttaattttg ctcattagtg caaacatttc
     2941 ttgcattttt cgcaaatttt caacaattat tttacagcgt ctaacaatga caagaatgaa
     3001 tctgcttgca agcttgcgcc accgactaaa gcaccgtcaa cattttcttt tgccatgtat
     3061 tcagcaatat tttctggttt tacagaaccg ccgtattgga tacgaactgc ttctgatact
     3121 tcttttccat aaagtttttc aactgtttga cgtacaactc cacaaatttc gtcagcgatt
     3181 tgtgcgtcag ctgatttacc agtaccgatt gcccagattg gttcataagc aataaccatg
     3241 tttgacacct gttcagctga aagatcagct aaaccagctg taatttgtcc ttcgatccat
     3301 tcagcagttt tgcctgcttc ataggtttct aaagattcgc cgcagcatag gattggtgtc
     3361 ataccatttg caaagatagc tttcgctttt ttattgatgt cttcgtctgt ttcatggaaa
     3421 tattcacgac gttctgaatg tccgatgatc acataatgaa cacctagatc agcaagagct
     3481 gctggtgaag tttcaccagt gaacgcacct gagttttccc agtagcagtt ttgtgctgag
     3541 atttttagtt ctgtaccttc agctgatgtc attaattctt gtaagaataa tgcaggagat
     3601 ccgatgactg aatcaacttt gtcatttgaa gggattttgt tttttactgc ttcagcaaat
     3661 tcttttgctt ctgatgcagt tttgttcatt ttccagttac ctgcgataat aggtttacgc
     3721 attgaggaac acactcctta atttattgaa aaatggctag ggagtcatga aaactccctt
     3781 caccttttgt tcgattactc gtcagaattg agcaaacttg gtcgtttatt tatcgttgat
     3841 tgctgctagt cctggtaatt ctttaccttc aagcaattcc aagcttgcgc cgccacctgt
     3901 tgagatgtgt gtgaatttgt cagcaaatcc taattgttct gctgctgcgg ctgagtctcc
     3961 gccaccgatg attgttgttg cgccttctaa gttagcgatt gcttcacaaa caccgattgt
     4021 acctttagca aagttactca tttcaaatac acccataggt ccgttccaaa caactgtttt
     4081 tgcaccttgt aatgtatcag caaataattt tactgatgct gggccgatgt ctaaagccat
     4141 caaaccatca ggaatgtctc cttcgattac ttgtgtttca acatcatttg aaaattctgg
     4201 tgcacagaca ttgtcgattg gcaagacaag tttgtcgcct gctttttcga ttaattcttt
     4261 tgctagttcc actttatcag cttctactag agagttaccg atcttgattc cttttgcttc
     4321 gtagaatgtg taagtcattc cgccaccgat caagatttta tctgctttag gaatcaagtt
     4381 ttcgattacg ccgattttat cagaaacttt tgcgccacca aggattgcaa tcattggtcg
     4441 ttttggttct tctactgctt caccgatgaa cttgatttct ttttccatca agaatccagc
     4501 aactgttggg ataccagttg aagcgatacc tacgttagaa gcatgtgcac ggtgagctgt
     4561 accgaaagca tcgttaacaa atacatcgcc taatgaagcc cagtatttac ctagttctgt
     4621 atcatttttg ctttcttttt taccgtcaat atcttcaaat cgtgtatttt cgaatacgac
     4681 aacgtcgccg tcattcatgt tgcggattgc ttcttctaat tgttctccgc gagtttcagg
     4741 tacgaatgtt acttctttac ctaataattc gcctagacgt tttgcaactg gagctaaaga
     4801 ttttccttct ttatcttctt ctgtttttac acgtccaagg tgagagaaaa ggattgcttt
     4861 tccgccttgt tctagaacgt agttgattgt tggcaatgct gctttgatac gagtgtcgtc
     4921 agtgatcacg ccgtctttca aaggaacgtt gaagtcaaca cggacaagaa cttttttgtc
     4981 ttttaaatcg atatctttca ctgttttctt agccatttta tttcctcctg aataaactta
     5041 ttatcaaaaa aagcggaaga agcgcgattg cttccccgct tttaaatgta catgtctata
     5101 atttacactt gtacgtttgt ctatcttata agttagcgaa gtattctaaa gtacgtacta
     5161 attgtgcagt gtatgacatt tcgttgtcgt accaagcaac agttttaact aattgtttgt
     5221 cgccaactgt cattacttta gtttgtgtag catcaaataa tgaaccgtaa gtcataccaa
     5281 cgatatctga agaaacgatt tcgtctgtgt tgtatccgta agattcgttt gaagcttctt
     5341 tcattgctgc attgatttcg tcaacagtta cttctttttc aagaactgtt actaattctg
     5401 ttaatgaacc tgttggtaca ggaacacgtt gagcagctcc gtctaattta ccgttcaatt
     5461 cgggaattac taaaccgata gctttagcag cacctgttga gttaggaacg atgtttgcag
     5521 cagcagcgcg tgcacggcgg aagtcacctt taggatgagg tccgtctaga gtcatttggt
     5581 cacctgtgta agcgtggata gttgtcatta atccttcaac aacaccaaat ttgtcgttca
     5641 atgttttagc cataggagct aaacagttag tagtacatga agcacctgag ataactgttt
     5701 ctttaccagt taatgtttcg tggtttgtgt tataaacgat tgttggaaca tcgtttccgc
     5761 caggagcaga gataacaacg cgtttagcac cagctgttaa atgtttttca gctgctgatt
     5821 tagaagtgaa gaaaccagta cattctagaa cgatatctac gcctagttcg ccccatggta
     5881 attcttctgg gttgcggtta gctaatactt taacttcttt tccgtttacg ttgaatgaac
     5941 cttcatgaac ttcaactgtt ccgttgaaac gtccttgagt tgtgtcgtat tttaacaagt
     6001 gtgccaacat tttagcatct gtcaagtcgt tgattgctac tacttcgatt ccatctacat
     6061 cttggatacg acggaatgct agacgtccaa tacgtccaaa accattaata cctactttaa
     6121 ctgtcattta agatttcctc cttatgaaaa tcaaaaaaat atttatttta aagggttacc
     6181 ccttttaaaa tctcatttgc agcagcttca tcagtgatga gccacgtttg ttttggtgca
     6241 tttttcatat aagctcgaat tgctttagct tttgattttc cgcccgcgat tgccatgatg
     6301 atcgggactt tttccaaatc ttgcaattct atgccgattc tagggacctt ataaacgact
     6361 tcaccttttt cattgaaaaa gtagccaaaa gattccgcaa cagcatttgc ttgtttcagc
     6421 atgactaatt ctttttcagt catcttacga cgtgctgcca tgtgtaatgc acgcccaata
     6481 ctatgaataa cacaattcgc ttcactaatc aagtttaaga cttcttggat agatggctca
     6541 ttgagtaaag aattgtaagt tgccagactt aattgttccg gaacataaag tgcgcggtgg
     6601 ttaccgtttg ctttagcagc cattcttgca ctgacagaat ttgcctgtac agttatcgct
     6661 tcaccaatcc cgcctcttgc agggacaaac aggttatgcc gtttcttatt ttccagatta
     6721 gacaattgtt cggctaccac agccatagta gttcctccca tcacagcgat gatattctcg
     6781 ccttctggaa gtagtcggtc taaggcttcg ctcagcgctt cgccgaatgc atcagccact
     6841 ttggtctgct cttcgctgtt tcctgaaaca acgatacagc gttggttacc aaaatattct
     6901 gccaactgtt gttcggtttg atgcgtacct aaaagctgat ccatgaagtt ttcaaggctt
     6961 tgataaactt cttcgccctt agttgtcagc gtcataccgc tttttgaggt gtcgatcaaa
     7021 ttcagatttt tcaaaaggtc tgtttctgtt cgtaagactc gttctgtgat ccccatactt
     7081 tccgataaac ttcgacgccc aatcggctgc atccaataga tatttcgtaa aattttatag
     7141 cgttcttgca acacttcgat aatatctggt gcaacagatt caatcatttt tatttcatcc
     7201 agcatagcga tctccttagt tggacacttt acgtccaatg tagacttaaa acgacccata
     7261 tacgataaaa aaagaaatta actattcgaa tttcacatca ataaagggaa atctcaacct
     7321 cacgactgta agtctaacag tttcgctctc gtttttcaac taaaaagact agaaaaagtg
     7381 aaatactttt tctagtcttt tgactgatta gttatcataa cgttttcttt ttgatgaact
     7441 cgggattcct aataaatcac gatattttgc tactgttcgt cttgagatcg ctatctcatc
     7501 ttttttcagc aattcaacca atttctggtc cgacaacggc ttgtttttgt cttcttgatc
     7561 gactaattcc tgcagctttt tcttcgctgt atctgctgaa aggtcttctg tctgttctgt
     7621 actattcgta ggaattcgtg tagtgaaaaa tttttttaat tcaaatacac cgaaatctgt
     7681 ttccaaatat ttcccgttga ctgcacgact gaccgtggat tcatgcacat ctatctcagt
     7741 tgcaacttcc tttaacgtaa gaggcttgat tggacgttcc ttgtcgataa agaaagcttt
     7801 ttgccgggaa acaatgactt gagcaacccg caaaattgta tccccacgtt gtaggatcgt
     7861 tttcttcaac cattcgaatt cctgtttccg ttcttttaaa taattttcag tttctttatc
     7921 tgcttgttgt gacatttgtt tgaagtaact ctcttgaaag cgtatatttg gctgattttt
     7981 tcggtttgag ataacttgta catttttatc gtcgtccact aatacccgga catcaggaat
     8041 aatgtacaat tcgctgctac ggtcgaaaat ccggccaggg cttggactca acgtttgtaa
     8101 atagtcgaat atctgctgaa cagcatgtag atcaacagaa aaacgttgtg cgatttcttt
     8161 ccattttcgc tccaccagtt cctcaaaaca ttcttccaac acgatataag ctaattccgg
     8221 cgcataatca tctcgttctg tttgaagcat gagacattct tgcaaactac gtgcacctac
     8281 tccagctggt tctaattgct gaatcagagt caacgcatcg agcatttgga taggcgtagc
     8341 tccaatctct tttccggctt cttctaaact aatcgtcaaa aatccgttca aatcgatgta
     8401 ttctacaaga taaagaacga ttttcctcaa aaaagtatct cggtaattca aatggacttg
     8461 ttcgatcaat gaatcaaata aagacccttt tgtatcagga atctgattta ggtaatttgt
     8521 ctcttctcct tcataagaag atgaagaagc ttttatgtaa tctggctgcc attccggctc
     8581 aacaacttcc accaatggat tttccattgc ttgattctca acgaatgcca acagctcctc
     8641 actgttatat tgtaaaactt ggatggactg ttgcaactgt tgcgtcatgg ctagtttctg
     8701 tgtctgctgc tgtttttgtg aaaaattttg ctcaaatttc atttttttgt ccaatcccct
     8761 tgtaattttt tatctgttta gttacaatta tcccagtgct tgcgtcctta gtgtagtgga
     8821 tatcacgtaa gattccggtt cttgagacgg gggttcgatt ccctcaggac gcgttctact
     8881 gctattttag cataatttac gaatagttgc ttctttattt ttaagtgaaa actgtccgcc
     8941 aaagaaaatt ggtggacagt tttttgttgt acctgtatag atattgttaa gcctttgcaa
     9001 gtaaggtagt tatgtgttca actacttatt aaaatgtgtt atttattaaa gatacttgtc
     9061 tcacttactg aactggccga tgatcgtttc tgccataata gttctcgaca gccgttggat
     9121 gccctaataa atccccaact gtcgtgatgc gatacccttg ctctttcaga taatcgatca
     9181 cttgaggaac ggcacgaatc gtttcaggat agatatcatg gaataaaata attgccccat
     9241 cgtatactgt tgcttggatc ttctgcaaaa tcaaatcagg atttcttgtc ttccaatctt
     9301 ctgaatcaac agaccattcg atgatcggtc gctggatgat cgttgctcct acattcgtga
     9361 cagaaccata gggcggacga acaaaagtgg gggttttgcc agtgactttt ttgatctcag
     9421 tgtctgcttt cgtcacttcc tccgtcatcg actgggcaga aagagtggcc agattctgat
     9481 gatcgtatgt gtaattgcca atctcgtgcc ctgcttcagc tgtctgcttc acgatttcag
     9541 gatgctgcgc cgtattttct cctaagacga aaaaagtggc atgcacgttt ttttctttta
     9601 agattcgcag aagctgcggt gttgtggtcg ctcctggtcc atcatcaaag ctgattgcga
     9661 cgcttttgac agccggatct cggctcgttt ttgtactgtc ttgtgttgat tgtgatgact
     9721 gactttgtac cttttccgct gattcttgaa tggcttcttt gacgttagct gtttcagttg
     9781 attggctttt aatggttgat tgttctgatt gtttgaaaga ttgtgacgaa tgctccgaag
     9841 agtgtgtttg tccttttact tcggtgatca aggaggccac cgaagtaatt tcgaaaaaca
     9901 aaagcacgga taaagcaata atactgataa ctaaataatt tcttttcact atatctcttc
     9961 tttctctttt tctcttctta ttatttactt gtacttactt gaaaattgaa actgctagtc
    10021 gcaactactt ctcgtctaat gatccaaata atcttccgat gccaaaatcg tttttgtcac
    10081 ggacttagga atgacaaatt ctggtgtacc catataacca ggagcaattt cgtattgaga
    10141 aaaagtcaaa actaattgat gctctttgtt caaataaaaa cttcgtgtag gcgtaacaag
    10201 tgttggtttt tctatcgtcc cttcttgaat atcttgctca gtccaatagt acttagatgg
    10261 atcttccttg acttgttcgg ccatctgccg tttgacttct tttgtcaaaa cagatagata
    10321 ggtgtcatct ttgaataaaa gtggaagtga gagctggaca ctgtttttct tgtcgattgt
    10381 gtcgtatctt ttttcaacat ggctatctgc tgctgtttgg gtgatctgcc tttcaatcac
    10441 gagaaaccgg ttatcgtcta cgattttctg ataatctccc aaaacttggt aatgatccgt
    10501 ttcaaaattt ccatattctt tttcagcttt ttcaaaatct gcttgtcctt cgcgaaagta
    10561 tttttgattt aatccatgaa ttgttttatt ttctttctca ttttgtgtat tgatcttcgg
    10621 tacctgaata tcgatttttt cagatcgatc agtaaagcgt tcgcctaaga tcaattcaat
    10681 gactgatcct aagatgggta aatcttctgc aaagcttcga acttgactat taaaaagaag
    10741 gctacttgtt gtaatcatta cgatagccaa agatactccg aacccttgga gacgtctctt
    10801 tctccgcttt gcttttataa atgattgctc ttcgataata aaacgctggc ggatctcctc
    10861 tttaagccct ttgggaattg cttgttcttt ataagttttc tttagttttt ttaaattttc
    10921 tttttgggaa tacatggcac tcttctctcc ttcattctag gatttgacgt aaagcattca
    10981 atgagcggta cattttcgtt ttaactgtgt tttcattcat atccaagata gtcgcaattt
    11041 ctttcaaacg aaatccttca aaaaagtaga ggatcagaat ctctttttcc ggactgtcta
    11101 ttttatctaa aatcatatgg agctctgcaa cggaagtttc taaaggtaac tgttggggga
    11161 tatcttgaat ttcaaataag tccacaggcg tccttttttg tctgcgccaa ctatctaatg
    11221 ccgtgcggat caatatccga taaaaccatg cactaaaatg ctcgatctct ttttcttttt
    11281 caaaatagtt cagggcttta tgaaaactat cttgcatcac atctaaggcc tcttctttat
    11341 catgtacgta attcatcgtg atacggaaca ttttttgata atcagtttcg atgagtccat
    11401 tcagcaggtg acggtatttt tcgatctgcc gttttttctt atatccagta aaaatcattc
    11461 tccactcctt tctgcctcac ttaatatgac gtacaaggtg cgctaaaagt ttcaattttt
    11521 ttatttttta tgtatttact tgggattttt atatacaaaa aagaaggtgt gacaaaaatc
    11581 gtgtcacacc tccttattct gataggctga tcgtctctgt cacaacctct cgtaagaaaa
    11641 taatgtttat tctttttcag agtcagaaaa ttcttcctct tcataatctt catcatcatc
    11701 gtcttcgtct atgatactta aatcttcttc gatatttcct ggcaagtctt cttcatcatc
    11761 tgtcgggtca tctgctccga tttcttgcaa gtcagaatta taagcagcga tttcttcatc
    11821 ttcatcatca tcgtcatcaa acagatcatc gtcatcttct tctgtcagat ctgtatcttc
    11881 tgggtcatcg tcattgtaat cgatcgcgtc ttcatcatca ttgataaagg cgttgacttt
    11941 cttgcgttta cggcgacgtg gagtatcttc atcctcttcg tccattccat ggtttacttc
    12001 ttcatcgatc gaatcgatag cataccatga acgcaagccc caacgattat cccctaatga
    12061 gataaagctg ccgtcaatat tcaagtcagt ataaaattgt gcgagtgaat cacgaatttc
    12121 actgtctgat ttcccaagat agttttggat ctggttagct aaatcagaaa aatccatgac
    12181 atcgccacgt tgttctaaga tcgcgtgtgc tacttcgatc attgataatt cgcttttgtt
    12241 tgcaccttca aatacactaa tttccaatca ggacacgtcc tttcacagtc tactccttat
    12301 catacaaaat cagacacaaa aaatcaaact tttcttttat atttacgctg taaaatccaa
    12361 ggtcaaataa tattcgccga ttttttccgg tcccatgaac agatcataat cgattcgaac
    12421 cttccctcct gtgggacggt ctttcaaact aacatgcagt tctttcgtaa aagtagcaat
    12481 ctggatcata ccgtatggtg ttcgatagga tgtttctaac cgttctttat agccaaattt
    12541 caaacgcatc cgcatttctc ctgcacggat cagctgtaca tgaccatctg gaactaattt
    12601 gatcgttaca ggaatctcat cgcccgtctc ctcctgaatc tctttataac gtatgtacag
    12661 cgtatcgcca attgtcacca tttgcccttt caaatcaaaa taaaaatctt gcacttcccc
    12721 ttgctgtttt acttttgtac gcaatttgat tgaaatcggt gttccttgtg ataattccat
    12781 tattcattct cctttacttc tcatagctac attgttccta gtttcttttg ttttgtcaac
    12841 caacttgtcc atttttacag aaaacctttt ttccaaaaca actctttgat tttagagtat
    12901 aatattgtag aaaatatgaa tttatacaaa ggagccggtt gaatgaaccc tgcgattcga
    12961 ctagatcagc acatttatca aaaaaacgac ttttcccctt ttgcattaac agatatatta
    13021 acggaatatt ctaaagaaca ccagcaaatc tttttacatt tctggcaata tgactgcaca
    13081 gtcatcttag gtatgaagga tgttcgaact ccttttctaa gtgacgggat ccaaacactg
    13141 aaagatgcag gttacgctcc agtgatcaga aattcaggtg gattagggat cgtatcagat
    13201 gaaggaattt tgaatatttc tttgattttc ccccaaagtg acacaaaaaa aataaccata
    13261 gatgacgctt acgagcaaat gctcctattg actaaatacg cttttccaaa ggcaccgata
    13321 caagcattcg aaatcaccca ttcttattgt cctggaactt atgatttaag catccatggc
    13381 aaaaaatttg ccggtatcgc tcagcgtcgg atcaaaaatg ggatttctgt tatgatgtac
    13441 ttaagtgtca acggtaatca ggaaaaacgc gggcaagtca tgaagcgatt ttatcaatct
    13501 gctttaaaag aagactttgg tacaaatggc tatcctgcag tggatcctgc tacaatggca
    13561 acacttgaag aactgcttga ccaacccctt tttgtaaaag aagtcaaaga agcatttgca
    13621 aaagcttttg aaaagctgta ttctgcaagt gatttacagg attctaccga ctggctaaaa
    13681 aaagaaatcc agctggagca atggaacaac caaatccaga gaatggaaca acgtaataac
    13741 ataaaggagc tacattatga caacccctta taaatatcaa atgctgccta tggaaaaagt
    13801 ttttcgtgat ccagtccata actatatcca tgtccagcat caagtaatct tagatttgat
    13861 caattcgaaa gaagtccaac gtctacgacg cattaaacaa ttaggcactt cttctttcac
    13921 ttttcacgga gcagaacata gccgttttac tcattcatta ggcgtttatg agatttcaag
    13981 acgaatctgc gatatctttt ctcgaaattt ttcaaaagaa aaaataggca acggaggctg
    14041 ggatgatcag gaacggctgg tgactttatg tgcggcactg ttgcatgatg tcggtcatgg
    14101 tccttactct catacatttg aacatatctt ccatacgaat catgaagcca tcactgtaga
    14161 gatcatcact tctccagaaa cagaagtgta tcagattctt aaccgagtag aagaaggttt
    14221 tcctgaaaag gtagctagtg tgatccaaaa aacttacccc aacccacaag ttgtccaaat
    14281 gatttctagt cagatcgatg cagatcgaat ggactatttg cttcgggatg cttatttcac
    14341 tggaacagaa tatggaacat ttgatcttac ccgaatatta cgtgtgattc gtccttatga
    14401 aggcgggatc gctttttcca tgagtggcat gcatgcagtg gaagattata tcgttagccg
    14461 atatcaaatg tatgtgcaag tgtacttcca tcctgtttcc cgtggtatgg aagtaatttt
    14521 ggagcatctg cttcatcgcg cacacgagtt gtatcaagaa gatgccagca gttttgaact
    14581 ccattctcaa ttacttctgc catttcttga cggaagcttt actttagaag aatacctcaa
    14641 acttgatgat ggggtcttgg gcacttactt tactcaatgg tctgaatctg ctgatcctat
    14701 tttaaatgat ttagctaaac gttttttgaa tcgtaaacca ctgaaatctg ctactttttc
    14761 tggcaaccgg gattcaaaat tagtccaaga actcactttg ttagtagaaa aggtcggata
    14821 taatcctgtt tattacactg ctgtgaattc tagctacgat ctaccttatg atttttatcg
    14881 cccagaacaa ggcagacatc gcacacaaat cgagattttg cgaaatgacg gaactttgat
    14941 agaattatca caggttagtc agcttgttgc tgcattagcg ggacaagaac aaggagatga
    15001 gcgatttttc tttccaaaag aaatggttga tccgtccttg cgtgatcatt atgatttatt
    15061 tgacgaaact tatcaagaat ttgccagcca tatccgtaat ggcgcattga ttgaaataaa
    15121 ttaaaatata ttggaggaaa ttatgtctat caaactagtc gctatcgaca tcgatggtac
    15181 tttattaaat gagaaaagag aagtaacaaa agaagtaaaa gaagcgattg ccgctgctgt
    15241 tgcaaaaggt gtttcgatcg ttttatgcac tggccgtccc ttaccaggtg tccaggaaca
    15301 gttaaacgag ttgaaccttt ttcaagataa tgattacgtt attacttata acggggcact
    15361 cgtacaacaa acgaaatcag gtaaaatcat cgcccgtcac ggactgacac atgaagattt
    15421 cctagagatc gaagtgatgg cacgccgtgt cggcagtcat ctccattcga tcgatgacaa
    15481 agcgatctac acgcctaatc gagatatcag cgcttatacg atccacgaag caagtttagt
    15541 caagatgccg ctaaaatatc gaacacctga agaaatgaca ccagacatga acatcgtcaa
    15601 aatgatgatg atcgacgaac cagaaatttt agatgcagca attgcgcgtt taccgcaaac
    15661 tttccgtgat aaatacacaa cggtcaaaag tgcgccctat tacttcgaag tactaaataa
    15721 agaagcaagt aaaggtgcgg cagttgcgaa tctcgcacag caccttggta ttgatcaaga
    15781 tgaaatcatg gctatcggag ataacgagaa cgacttatcc atgattgaat atgctggtct
    15841 aggagtagca atgggaaatg ccgtttctct tgtcaaagaa gcagcaaatg tcatcacttc
    15901 atcaaacgac gagcacggtg tagctgaagc aatcaa
//
LOCUS       DACDAF010000067        15513 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.067, whole genome shotgun sequence.
ACCESSION   DACDAF010000067 DACDAF010000000
VERSION     DACDAF010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.067"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(21..251)
                     /locus_tag="IVZ69_001974"
     CDS             complement(21..251)
                     /locus_tag="IVZ69_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184049.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="IVZ69_001975"
     CDS             complement(687..1253)
                     /locus_tag="IVZ69_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HAP8184050.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="IVZ69_001976"
     CDS             complement(1253..2209)
                     /locus_tag="IVZ69_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HAP8184051.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="IVZ69_001977"
     CDS             complement(2209..2865)
                     /locus_tag="IVZ69_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HAP8184052.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="IVZ69_001978"
     CDS             3235..5253
                     /locus_tag="IVZ69_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP8184053.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     gene            5680..8094
                     /locus_tag="IVZ69_001979"
     CDS             5680..8094
                     /locus_tag="IVZ69_001979"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016183651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HAP8184054.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="IVZ69_001980"
     CDS             8442..9995
                     /locus_tag="IVZ69_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP8184055.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="IVZ69_001981"
     CDS             complement(10376..12160)
                     /locus_tag="IVZ69_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8184056.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="IVZ69_001982"
     CDS             complement(12175..13896)
                     /locus_tag="IVZ69_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8184057.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="IVZ69_001983"
     CDS             13996..14757
                     /locus_tag="IVZ69_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP8184058.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         5052 a         2811 c         3032 g         4618 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tct
//
LOCUS       DACDAF010000068        15018 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.068, whole genome shotgun sequence.
ACCESSION   DACDAF010000068 DACDAF010000000
VERSION     DACDAF010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15018)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15018)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15018
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.068"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..1158
                     /locus_tag="IVZ69_001984"
     CDS             <1..1158
                     /locus_tag="IVZ69_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8184059.1"
                     /translation="FIVYLIYYLLMVIMAVIAQDTLHASLSQAGFASGIYIIGTLLAR
                     LFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYLVRFLNGFGYGTVSTATN
                     AIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMTDFRFIIWFSIVLVFFVT
                     IACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIAFLMGLSYSSVLSFLSSY
                     TKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVMYPSYLFLTAGLFLLSVT
                     TNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIALSTYFIGLDLGLGVGPYL
                     MGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEGELIESLKNEI"
     gene            complement(1306..1671)
                     /locus_tag="IVZ69_001985"
     CDS             complement(1306..1671)
                     /locus_tag="IVZ69_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HAP8184060.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(1818..2591)
                     /locus_tag="IVZ69_001986"
     CDS             complement(1818..2591)
                     /locus_tag="IVZ69_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP8184061.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            complement(2765..3625)
                     /locus_tag="IVZ69_001987"
     CDS             complement(2765..3625)
                     /locus_tag="IVZ69_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HAP8184062.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            complement(3625..5043)
                     /locus_tag="IVZ69_001988"
     CDS             complement(3625..5043)
                     /locus_tag="IVZ69_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8184063.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSISTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            complement(5100..5549)
                     /locus_tag="IVZ69_001989"
     CDS             complement(5100..5549)
                     /locus_tag="IVZ69_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP8184064.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            complement(5994..6257)
                     /locus_tag="IVZ69_001990"
     CDS             complement(5994..6257)
                     /locus_tag="IVZ69_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HAP8184065.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            complement(6356..7651)
                     /locus_tag="IVZ69_001991"
     CDS             complement(6356..7651)
                     /locus_tag="IVZ69_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HAP8184066.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPARNLKR"
     gene            complement(7648..8919)
                     /locus_tag="IVZ69_001992"
     CDS             complement(7648..8919)
                     /locus_tag="IVZ69_001992"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP8184067.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            complement(9084..9953)
                     /locus_tag="IVZ69_001993"
     CDS             complement(9084..9953)
                     /locus_tag="IVZ69_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HAP8184068.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            complement(10245..11855)
                     /locus_tag="IVZ69_001994"
     CDS             complement(10245..11855)
                     /locus_tag="IVZ69_001994"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HAP8184069.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            complement(13047..14387)
                     /gene="glnA"
                     /locus_tag="IVZ69_001995"
     CDS             complement(13047..14387)
                     /gene="glnA"
                     /locus_tag="IVZ69_001995"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HAP8184070.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            complement(14415..14807)
                     /locus_tag="IVZ69_001996"
     CDS             complement(14415..14807)
                     /locus_tag="IVZ69_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HAP8184071.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
BASE COUNT         4228 a         3225 c         2584 g         4981 t
ORIGIN      
        1 tttattgtct acctgattta ttatctgttg atggtcatca tggcagtcat tgcgcaagac
       61 accttacacg ccagcttgag ccaagcaggt tttgcttctg ggatctatat catcggaaca
      121 ttgctggcac gcttattcat ggggaaacag ttagaactat ttggtcggaa gtttacctta
      181 agaggcggcg cgatcttcta tctcctttca acattagcat atctttatac gccaactatc
      241 ggggcattgt atttagttcg attcttgaat ggattcggct acggtacagt ttctacagct
      301 acaaatgcta tcgttactgc atatatccct gcatctaaaa aaggggaagg catcaattat
      361 tatggattaa gtactagttt agctgccgct gttgggccat ttttaggaat gattttgctg
      421 aatatgactg attttcgttt cattatctgg ttttcaattg tactggtctt ctttgttacg
      481 attgcctgcc ttgtctttcc tgtaaaaaat attccattat ctgaagaaca aaaaatatct
      541 cttcgctcat ggaatatcaa tagttttatt gaaaagaaag cacttttcat tacaggaatt
      601 gcctttttga tgggtctttc ttattcaagt gttttatcat ttttatcttc ttatacaaaa
      661 gtaatccact tagttgctgc tgggtcattt ttcttcgtcg tatatgcttt ggtcatcaca
      721 tttacacgtc cattgactgg aaggattttc gatgtcaaag gagaacaata cgtgatgtat
      781 cctagctatt tattcttaac agcaggatta tttttactga gtgtaacgac gaatagtgtg
      841 acattgctta tctctggagc attagtcggc ctaggttatg gtacgtttat gtcaaatgga
      901 caggctgttt gtttaaaaat cgtccgcgaa catcgaatca gtattgcttt atctacctac
      961 tttattggtt tagacctagg cttaggcgtt ggtccttatt tgatggggat gctaaaatct
     1021 cttacttcat ttagaggatt gtatgtgatt gccggagtca ttccattgat atgtacagca
     1081 ctctatcttg ttaatggccg aaaacatagt catgaagcag agggcgaatt gattgaatca
     1141 ttgaaaaatg aaatttgatc ttgatgaata gataaaaaaa accgttcaga tctgaaaata
     1201 atctgagcgg ttttttgagt aaaaatagtt tatgattatt cttaattaaa catctattta
     1261 tttttaaagc tttcatttat cgataagaat agtttaactg ttgatttatt ccattttccg
     1321 ttcatctggt acgatgcctt gacttagcaa ccacttgtgg aagaaccatt ctgccacacc
     1381 gatcaataga gcaggaatca atactttcat ccaaatatcg actgtatcat tcataaaata
     1441 tagatagagc cacaagataa ctgcagctga accagcatct gcgatcgtcg ctgcgatgtt
     1501 ccctacttta cgtaagatca acagatcccc tagcacatag atcatgacta caataattac
     1561 cccaacaatc gttgaatcca taaagctaac accgtataaa cctgtcagca cgacccacag
     1621 aatcgcccag atcatgattg ccttcactac caacgccttc acatgtttca ttttctgcac
     1681 tcctttctcc tggataaaaa agtaagatta tctaacaaga taaccttttc attattatac
     1741 catcggctga gagaagcgag caaagataag gtcctatcta aaaatgagga agccacttag
     1801 aacattcacg taataattta tccgtacaga cattcgatat ggtgttcctt tactttcgca
     1861 tactgttctt ttgtcagttc tttacttgtc accagataat cgatttcatg aaaagcaatg
     1921 gcttgatgca tgaatttatg tgcaattttt tgctgtgtaa ctaaaacggc aagccggtct
     1981 gattgttttc taaaagcttt tttgaccatt gcctctcctt catgagtttc tgttactcct
     2041 tggctgaaat ctagcccgcg acaactcatt atcgctaaat ccgcataata tgacaatgca
     2101 tcgttatagg cttttgaacc gttgattgtt gctcgtttcg gaacaattgc ccctcccaat
     2161 acagatactt ttgccgttgt atattcactc aacatagcag ctgtgacgat gccattcgta
     2221 atgatctgca aaccatcaaa tcttgctagg tttctgacta agtgtaaaga ggttgtactg
     2281 gaatccaaga ataagaccat atcatctcga atcaaagaag aagctgtatc tgcaatctta
     2341 cgtttttctg tttcttcttc taatttggtg atcttcatca ggtaaggcac gtcaattttt
     2401 cgattgtcaa taagcatggc gccaccgcga actctacgga tcaatccact tttttccaga
     2461 aaaacaaggt cacgtttaat cgtggcttcg ctataattta ctaactcgat caaatcggtg
     2521 actcttgcaa attggttgtt ttttagataa ttcacaatct cctgctgtct attctccact
     2581 tcattcaaca taaaatcacc ccatttactt tatatagtaa caggaaaaaa gaggttgtga
     2641 cagaagtgat tggcttcgag aaataagaag aaatttttcg aaaaaactac ttctgaacat
     2701 cgtgtgtggt taagagggta tgacaagact attgtcatac cctcttgacc acacattttt
     2761 atttttagta taaactagcc ttgcctactg tgttcaaaat ttccatttta tgtttgacta
     2821 cttcttgtac ctttttatta gctgctggat aaattgcatt cggctcgtac atcgatggat
     2881 tttcactcaa tatttctctc aaagcattga aaaagacgct tttaagatct gagctcaaat
     2941 tcactttggc aactccgtat tttactgctt cgctgacttc tgcgtccgga ttacctgaac
     3001 cgccatgtaa aacaaatgga agatcgattt gttggttcaa ttctttcagt aagtcgatat
     3061 ttaattttgg agttctgttt ttcggataca agccatgcgc tgttccaatt gctacagcaa
     3121 gtgtatcgat tcctgtttct ttcacaaaaa tcttcgcttg atcaggatct gtataaatga
     3181 ttgtttcagc acctccttca gcagaaccat tattcccaat cgttccaagc tcagcctcca
     3241 ctgagacatt taccgcatga gctaacgcaa ccactttttt cgtaatctgt acattgtcgt
     3301 cgaatgattt caaagacgca tcgatcatca cggaagaata gccgtttcga atcgcccgta
     3361 agacatcttc tatcgtaccg ccatgatcca agtggataac gatcggcagt ttacttgtat
     3421 aagcataggc tcttactgcc gcaacaaact catcacttaa ataggcgatt tcatcaggat
     3481 gaatttctaa gattactggt gcttctaatc tctctgcttc ttcgatgatt gctttcatca
     3541 tatcatagct gcaaatattg aaggctggta ctgcaaattg attctcttta gccactttca
     3601 ataactcttt cattgtatat aacattacgc ttccacctca tttgttagat tttcattttt
     3661 cgtccacttg tcttgttttt tctctttcac tgtttttttc aatagtccaa gcataaaggc
     3721 tgtagtgact gtacctgatg caattgccaa gacatacata ggtaaattgt tcataacatt
     3781 tggaattagc atcacccaaa tccctccatg aggtgccatt gaagtaactc ctactgccat
     3841 ggaaatccct gcagcgactg ctgaacctgt catcaaacta ggtatcacgc ggatcgggtc
     3901 agataccgca aacggtatag caccttctgt aatatacgaa gcgcctaaaa tccagcatga
     3961 ttgacctgaa gtccgttctt ctttggtaaa tttatgtttg aataataaag tggctaaagc
     4021 aatacctagg ggaggtgtca ttcctgcagc catacaagca gcaatcggtg catttactcc
     4081 agctgacatc aaaccgatcg agaaagtcga aatcgattta ttgatcggcc cacccatatc
     4141 agctgccatc atgatcccga taagtaatcc gaacaatagc ccggatgtat ttcccaagct
     4201 attcagccaa tttgtcaaag catccaacac ccatgtgatc ggttgttcaa tcacaaatac
     4261 catcaaaagc ccaataatta agatcgataa aaaggggacg acaatcagct gataaatagc
     4321 agaaaattct ttttttacgc taattttatt tgccagaaaa tcacagatat accctgctag
     4381 cacgccacca atcattccgc caagaaaacc tgaaccacct gtagaggcca gtaatccggc
     4441 aacaattcct ggggcaaaac ctgcttttcc agcaatcgat gtagcaatcc ccgcgcctaa
     4501 cgcaggaacc atcatggcaa acgctgtatc tcctccgatc cttgaaaatg cagctgctaa
     4561 cacattatag tctgctgagt tgggatcagc cgctgtaatc ccaaaggcaa aactcagtgc
     4621 gatgatgatt ccgcctgcga tcacaaatgg aagcatgtaa ttcacaccat tcatgaaatg
     4681 attatagatt gtcggctttt tctcatttgc agctggttct ttttcattag acacaacgaa
     4741 tacgccaata tctctcaatg cttcgtctat tactacttgc ggttctttga ttgctcggct
     4801 tgtagagaca cgctttactt ttttcccggc aaatcggtcc aattcgattt ctttatctac
     4861 tgcaagaatg attgcatctg cctctttgat ttcttgttca gataactgat tttctgtttt
     4921 tacaccttgt gtttcgaatt ttgcttgatg gtttagattt cttgctgtta cttctaattt
     4981 ttctgccgac atataagtat gagcaattcc agtcgggcaa gcagttacac caacgatttt
     5041 catgattatt ttcctccttt ttcttcacta tcgatactcg gacaaagact ctactatttt
     5101 cattcttgac taatctgtct gatgatatct gctggcgtag tggcttcttt tattcccttt
     5161 ctaaaatctg cattcatcaa tcgtctggag agtgtgctga gaatctctag atgcatatct
     5221 gctgattttt caggaactac gatggcaaaa atatattcaa ttggcatttc atctatcccg
     5281 ctatagtccg ttaatttggc tgtatgaaaa aaacacagtg ctggttttgt cacatatttg
     5341 ctttttgcat ggggaatccc aaatccatct tctattcctg tggagatctc ctcctctcgt
     5401 ttgaatagtg ccttaacgac tttttgaaca tttcttacct tatttgtttt tttcaacaca
     5461 tcccctattc gctcaaataa tgatcctttt gaatctatcg atggatcgaa aacaatcagt
     5521 tcttctgcga tcaattgatc aaacctcata aaaaacctct cccccacaaa aaatgttaac
     5581 gttttcttgg aactgaggtc agtatagcat cgctagctgt accgttcaat attatgaatg
     5641 aacagaggaa aaagacccat catccgcgtg tataagtcat taaaatgaac gatctagctc
     5701 acaaacaatc gcaagtctat aacaaaacaa aaagccttcc ttgaaaggaa agcttagctt
     5761 ctaattttag gtaaatggtt ttttacttcg aaataacccc tcttcatttc gttaatataa
     5821 ggtgttttta tcaagtggat aattaaaact atatactagt ttttcattgt tttgtgcatt
     5881 atgatcctac gactttttca gcatcaaacg aagttttaaa ttggcaaaaa acataaaaaa
     5941 acagactatc cctatcagat agtctgctaa acgttgagtt atcagcgttt ttattattcc
     6001 gcagcgtttg cgtctttgag accgtatttt ttgttgaaac ggtccacacg tccgtctgct
     6061 tgtgtgaatt tttgacgtcc agtgtagaat ggatgtgagt cagaagttac ttcgacacgg
     6121 atgactgggt atgtattacc gtcttcccat tcaactgttt cttgtgaagt ttttgttgaa
     6181 cctgacaaga atttgaaacc agttgttgaa tccatgaata ctactgggtg gtaatctgga
     6241 tggatgtttt ctttcatgat tttttcgctc ctttgccctg ctccatttgc tgaaccagag
     6301 ttgatttgtc gatttacaac attaacatct taacatgttt cagtcaaggt tgcaattatc
     6361 ttttcagatt tctggccgga ttttttttac caaaggagac atcttgaaat tctttgaaaa
     6421 attgctgatt gttttttgtt ttacgcaaaa agcggatcag ttgttccgta tattctaatg
     6481 aatctccagt catatttttt cgaagtttcc aaatttcttc taattcttca cttggcatca
     6541 ataattcttc ttttcgggta cctgattttt tgatatcgat ggctgggaag atccgacgtt
     6601 cagataattc acgtgaaagt tgtaattcta gatttccagt tcctttgaat tcttcataga
     6661 tcacgtcatc catacggctt cctgtatcga ctaaagcggt cgctaaaatc gtcaaactgc
     6721 caccttcttc gatgtttctt gctgccccga aaaatttctt aggtttatac aatgcggctg
     6781 ggtcaatccc gccactcaat gtacgtccgc ttggtggaac gactaagtta taggcccgag
     6841 caagtctagt aatactatcc atcaagataa cgacatctcg tttatcttcg actaaacgca
     6901 ttgcgcgttc caatactaat tcagaaactc gagtatggtt ttgcggctgc agatcaaatg
     6961 tagaagatac cacgtcgcct ttcacgcttc gttctagatc cgttacttct tccggtcgtt
     7021 catcaatcag tagaacgatt aattctactt ccggatagtt ttcggtgata ccatttgcga
     7081 tttcttttaa tacagaagtt ttccctgctt ttggcggtgc gacgatcaat ccacgctgac
     7141 caaaaccgat tggagaaaag atatcgatca ttcgggtaga tagtctttgc ggtgttgttt
     7201 ccagttgaag ctgtctttgc ggataaagag gtgttaaggc tggaaaatgc ggacgttctt
     7261 ttgcttcttc cggatctttt ccattaacgc tttccacgtg catcaaacca taataacgtt
     7321 ccgattcttt aggtggacgg gcttttcctg ccactttgtc cccatttctc aaactgaatc
     7381 gtctgatttg tgaggcagaa atatagatat cttctgcact tggtccataa ttgattggcc
     7441 gtaaaaaacc gtaaccatct tgaccaacga tatccaatat tccttccata taataaaatc
     7501 cttgtttctc tgcttgtgca cgaatcacag ctagagataa ttccttttta ttcatcttac
     7561 tgtaataagg aattttaaat tctttggcat aactataaac ttcttttaac gttttgttct
     7621 ctagttctgc cattgtcaaa taatcgctca ttcagctccc acttcctcta tcatttcaat
     7681 tgatgcccct aaggctgtta gtttctcgat aatatgatca taaccgcgta agatataatc
     7741 tacattgtaa atcgtcgttg tcccttctgc caatagtcca gcaatcacta aacaagcacc
     7801 tgcccgaaga tcagaagcca cgacttctgt gccgtgaagt ttatttggac cattcacgat
     7861 gatcatattt ccttccacgg taatatcagc gcccattcgt gctagttccg gcacatggtt
     7921 cacacgtttc gcatagatcg tatcgatgat ttctgaagtg cctgtagtca tcaatagtaa
     7981 cgcagtaagt ggctgctgca gatctgtggc aaatcctgga taaggatagg tcatgatgtt
     8041 tgcgggtttt aattctttcg aggggtaaac ttcgatttca tcttcgctga ttttcatatg
     8101 gacaccaatt tcctgcaatt ttgctataaa gctttccaaa tgttcaaaga tcacattttt
     8161 cactttgata ccatttccta ctgcagctgc taatgctaga taggttcctg cttcgatgcg
     8221 gtcaggaatc atgaaatgcc gacagccatg taatgtttcg actccttcga tacggatcac
     8281 atctgtaccc gctcctcgaa cttttgcccc catattattc agtaaagttg ccacatctat
     8341 gatttccggt tctcgtgcag cgttttcaat tactgtctgt ccttttgctt ttacagcagc
     8401 taacatcaca ttgatcgttg ctccgactga aaccacgtcc atgaaaatcc gattgccacg
     8461 caatccttta ttttctgtcc gtaaatacat ggcaccatgt tcatttgtca cttcagcacc
     8521 tagagcttca aatcctttga cgtgtaggtc aatcggtcta gggcctaaat aacagccacc
     8581 tggcaggcct actaccgctt cgccaaattt accaagcagt gttcccataa aataataaga
     8641 agcacgcaaa ctattgattt ttccgtgcgg catcggaatc gatacgactt ctcgaggatc
     8701 gatttctagt atgttgttgg aaaaatggac agttgcgccc atgatctcta aaatttcaat
     8761 taatgaatga acatcttgta tgtccggcac accttccaag atcactgggg aatcagctaa
     8821 gattgcagct ggaatcaatg cgactgcact attttttgca ccgctgatcg ttacttcacc
     8881 agctaaaggt cggtttcctt tgattacgat ttttttcatc tgtttccacc ttgtttatta
     8941 atcttttttc atggatatgc ttgtatttta tcatagataa aaaaaagaaa cgagcatggt
     9001 ctgccgtttt aagtaaaaaa gaatggagag cgacttcaaa agtcgttctc cattcctata
     9061 tatcgtatct gttatgtgga tgcttacgct ttgttagctg aaccgaacca gtcgatatga
     9121 gatttagcat cttcaacgat tgctgcttta cctggagcta ataatttacg agggtcgaat
     9181 cctttacctt ctttatcttt accagcttcg atatatttac gagtagctgc agcaaatgat
     9241 aattggaatt cagtgttaac atttactttt gagataccca ttgagatagc tttttcgatt
     9301 tgatcttgag gaatacctga tccgccatgt aatactaaag gcatgtctgg acctacagca
     9361 tcagcaattg cttgtaagtg gtcaaaagct aatcctttcc agttttctgg atattgacca
     9421 tggatgttac cgataccgca agctaagtag tcgatacctg tagcaaccat ttgtttgcat
     9481 tcttcaatat cagctaattc gccgttaccg atgattccgt cttcttctcc gccgattgaa
     9541 ccaacttcac attcaactga gatacctttt gcatgtgctt tttcaacaac gtctttagct
     9601 aatttcaagt tttcttcaaa tggtagatgt gaaccatcga acattactga agtatagcct
     9661 aattcgatac attccaaagc agcttcgtaa tcaccatggt ctaagtggat agcaactgga
     9721 acagtgatgt tcattgcttc aactaaatca gtgattaaat ctttacagat tttgtaacca
     9781 cccatgtatt tagctgcacc cattgatgtt tggataagta ctggtgcttg ttttgcttca
     9841 gccgcttcaa ggattgcttg agtccattcc aagttgtttg tgttgaatcc gccgacagcg
     9901 taaccgcctt tacgagcagc ttttaaaaat tcagctcctg atactactgg cataataaaa
     9961 ttcctcctaa gttttgtaaa actaaatttg ttaagacaat tcttaaccaa cgaccctatt
    10021 ttaccaaaca tttcggtagt tttctactaa aatcaatgaa aatgaaaatt ttcaagaagt
    10081 tttttgcaaa aaataaaata tccaatagcg ctttaatcga aaaaagtctt ttgctttcta
    10141 tcttttttcc tacaaataat aacaaattag aaaaagagaa aagtgacaag aaaattgctt
    10201 atccccttct cttgctactt ttctctttct atcaagttca aaaattattt tgtttcgtga
    10261 tctgctaatg atgctccgac aaatgctttg attaattttt gcgggcgatt tggacgagaa
    10321 atcaattctg ggtggaattg gcatcccaca aagaattttt tctctggcag ctctacgatt
    10381 tctactaaac ggttatctgg tgagacacct gaaaagacta gcccttgttc ttcaaacaat
    10441 tgacgatatt tgttattgaa ctcatagcgg tgacggtgac gttcttgcac aacatcggct
    10501 ccatcatatg cttcagccgt cttcgttcct tttttgattt tacatgggta taatccaagg
    10561 cgtaaagttc cacccaaatt ctcgatgttt tcctgatcag ccattaaatc aataatattg
    10621 tttgctgtat ctggattcgt ttcagctgat gacgcatctt ctaatccaac gacgttacgt
    10681 gcaaattcga cacaagccat ctgcatacca agacaaatac ctaaaaacgg aacgtcattt
    10741 tcgcgagcat aacgaatcgc ttcgattttc ccttctactc cgcgatcacc aaatccacca
    10801 ggaaccaaga ttccatctgc gtctttcaaa cgttcttcta cattttctct cgttaattct
    10861 tgtgctttga tccaatcgat ctcgatgtct gaattatagg cgaaaccaga atgtttcaat
    10921 gcttcaacta ctgagatata tgcatctggt aactcgacat atttaccgac aagcgcaatc
    10981 cgtacttttt tcttcaagtt caagacacgt tcttctaatt ctttccattc tgtcatgtct
    11041 gcttctggtg tatctagttt taaatggtcg caaacaattt gatccattcc ttgtgcttgt
    11101 aaaactaatg ggatggagta aagtgtatct acatctggcg actcgataac tgcttctggt
    11161 tcgacatcac aaaattgtgc caatttgttt ttcacgcttt gagaaacagg ttgctctgta
    11221 cgtaccacca aaatattcgg ttggatacct aaaccacgta gctcttttac actgtgctgc
    11281 gttggtttag ttttcatttc tccagcagct ttcaagtaag gaatcaatgt tgtatggata
    11341 tacataacat tatctgtacc gacatctgct ttcatttgac gaagtgcttc aaggaatggc
    11401 aaagattcta tatcccctac tgttccccct acttctgtaa tgatcacatc tgaatcagtc
    11461 attttagctg ctcgcatgat tttttctttg atctcatttg taatatgagg aataacttga
    11521 acagttgctc ccaagtattc gcccttacgt tctttacgca aaacttcaga atagattttt
    11581 cctgtcgtca cgttggagta tttgttcaaa ttgatgtcaa taaaacgttc gtagtggccc
    11641 agatccaaat ctgtttcagc accatcatct gttacgaata cttctccgtg ctgatatggg
    11701 ctcatcgtcc ccggatccac gttgatgtat ggatcaaatt tttggatagt tacttttaag
    11761 ccgcggtttt tcaataagcg tcctaaagaa gctgcaacaa tcccttttcc gattgatgaa
    11821 acgacaccgc cggtcacaaa aatatatttt gtcataagtt caaaaactcc tttttaattt
    11881 atgtgcagga aaagtctcag acaataaaca aagctcccta ttcttcaata agaataggga
    11941 gccgaaattc tgtaaacttc tgaccctcta aaagggtgcc caaggtgtat aatacaagct
    12001 gactaaggga aagtcaagta ctcaaatgaa tactatccgc ttacaatttt ttctttttcg
    12061 atatcctttg agaaattatt tcttaagtcc tttatgagtg caaaaaaaat ttaacccaca
    12121 taataagctt gatataaaca tagctaacgt taaacctaag caaatcagaa aatcgttact
    12181 gaaaaatttt aagtgaaata atagataaaa aaataaaaca aacattatga tagataatat
    12241 cccacctaac aaagaactac tttttcctac ttgcagcaac agtttatata gcttatcgta
    12301 gaaacaatct ttttctttca cccttattta cctcctttac gtaaaaaacg tagtccacag
    12361 ttctcggatt tttggcatat cttttctatt aaataatatc aaaaacaaaa caattccact
    12421 aattttttca aagatgacct ttttttcaac aaaagtgcct tgtagggatt cattgaaggt
    12481 aacgaatcac ataagtaaaa aataaggaga tgcgacaaaa gtcgtgcctc cttatttcta
    12541 aataaacggt gttctcctgc caactcctcg gtcacaagtc acaatatcca tcaaacatga
    12601 gaagctgttt ttgaaattat ttcttgtgat tcggagttaa atggtaggct cacaacctct
    12661 ggataaacgg tattcaaaag ccagtttctc ggtattaagc caaatttatg caaaaatgta
    12721 gaaagccatt ttcacaaaat ttttcttaat actcgaaact aaacgtcttt ttcaaaacct
    12781 cttggtaaac ggtgttcaaa agcttgcatc tgcggtaata agttcagcca attcaaaaac
    12841 aagaaaagct gtttttgctt ggctattctt attacttgtt gcagggcagc tttttcacaa
    12901 cctctccact aaacggtgtt caatcagctg accctcggta ttagctcaaa aaacggcaaa
    12961 atatgaggaa ctatttttcc gttagtttct ctaatactca ggtcaaaacg ctgatttcac
    13021 agcctctaat tcacggtatt cctgttttaa taaagttcta gatattgttc tctttcccac
    13081 tcggaaacag tttgtctgaa tgccgcccat tcgagacgtt ttgcttcaac aaaatttgag
    13141 aagatatgtt gtcctaatgc gtcaatcatt acattatcct tacgcaattc tttgatagca
    13201 ttatggatag ttgaaggtaa gtcctggata tgtgcagctt ctctttcttc ctcatccatt
    13261 acataaatgt tacggtcaac agctgctggc ggtgtgatct gattacggat accgtctagt
    13321 cctgcttgca acaatactgc cattgccaag tatgggtttg cagatggatc aactgaccgc
    13381 aattccaaac gtgtggataa accgcgagat tctggtacac gtactaatgg cgaacgatta
    13441 cggccactcc atgcgacata aacaggcgct tcataacctg gaacgagacg tttataagaa
    13501 ttgactgttg gattgcaaac ggctgtgtag gcacgagcat gtttcagcaa accacctaag
    13561 aaatgataag ctgtttcact tagttccaat tcaccgtctt tatcatagaa aacatttcct
    13621 tcatcattga acaaagacat attgcaatgc ataccagaac cattgatccc aaataacggt
    13681 ttcggcatga aagtcgcgtg aagtccatgc ttgcgtgcaa tcgttttgac aacgagcttg
    13741 aaggtttgga tattatcaca agcatctacc acatctgcat atttaaagtc aatttcatgc
    13801 tgtcctggcg ctacttcatg atgtgaagct tccacttcaa agcctagact ttctaattcc
    13861 aacacgatgt cacggcggca attttcacct aaatctgttg gtgcaaaatc aaaataacca
    13921 cctttatcat tcaaggtcgt tgtgatccca ccgtcttcgt ctaatttaaa taagaagaat
    13981 tctggttcag gtcctaaatt gaaagaggta aaaccaaggt cgcgcatatc tttcaatgct
    14041 cgtttcaaat tcccgcgagg atcgccggca aatggtgtcc catccggatt atagatatca
    14101 caaattaaac gagcaacttt tccatgagca ctttcccacg ggaagatcat ccaagtggag
    14161 agatctggat acaaatacat atcgctttct tcaattcgaa caaatccttc aatcgaagaa
    14221 ccgtcaaaca tcattttatt ttctaatact ttgtcgatct ggctcactgg aacttctaca
    14281 tttttgatcg tacctaagat gtctgtgaac atcaatcgta aaaatcgtac gttttcttcc
    14341 tcaatgattc gtttgatttc ttcacctgtt atctgtttct ttaccatggt atccctcttc
    14401 cttttttaat ttattcagtc aaagaattgt ctttgcaatc cttgcgactg ataatgacct
    14461 gttttgctta acccaccttg cgccaaaatc tcatcacgaa aaatttgtcg aacgtcatga
    14521 tctgtcaacg gcttcttgtt ttttgcttct tgttttttcg cctgtgccat ttcgtataca
    14581 cgtttgatcc cagccatatt caatccctct gaaagatagt ctttaatctc aagcaacata
    14641 tcaatatcat tcagcgaata catacgtcgg tttccttcgc ttcgttccgg atgaactaaa
    14701 tcttgttctt cataatagcg aatttgccga gcagacaaat cagtcagctt cataactgta
    14761 ccaattggaa atacggacat agatcggcgc aattcctttt ctcccatcag acgtcccctt
    14821 tcgttttata agttggctaa agtgtaccaa ttaaaaaaaa tattgtcaac tgcatatgtt
    14881 aggttttcta acatgagatc tctatttttt ataaaataac aaaaaaataa gaacacaaaa
    14941 aaggtatcta gttgattttc gtaccagata ccttttattt tttattatac tgtactatcc
    15001 tttattagtg tttttatt
//
LOCUS       DACDAF010000069        14534 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.069, whole genome shotgun sequence.
ACCESSION   DACDAF010000069 DACDAF010000000
VERSION     DACDAF010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.069"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            141..461
                     /locus_tag="IVZ69_001997"
     CDS             141..461
                     /locus_tag="IVZ69_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184072.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            913..1113
                     /locus_tag="IVZ69_001998"
     CDS             913..1113
                     /locus_tag="IVZ69_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP8184073.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1260..4049
                     /locus_tag="IVZ69_001999"
     CDS             1260..4049
                     /locus_tag="IVZ69_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP8184074.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4096..4623
                     /locus_tag="IVZ69_002000"
     CDS             4096..4623
                     /locus_tag="IVZ69_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HAP8184075.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4644..5834
                     /locus_tag="IVZ69_002001"
     CDS             4644..5834
                     /locus_tag="IVZ69_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HAP8184076.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5874..7172
                     /gene="asnS"
                     /locus_tag="IVZ69_002002"
     CDS             5874..7172
                     /gene="asnS"
                     /locus_tag="IVZ69_002002"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HAP8184077.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8225..8899
                     /locus_tag="IVZ69_002003"
     CDS             8225..8899
                     /locus_tag="IVZ69_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP8184078.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8896..9237
                     /locus_tag="IVZ69_002004"
     CDS             8896..9237
                     /locus_tag="IVZ69_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184079.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9267..9626
                     /locus_tag="IVZ69_002005"
     CDS             9267..9626
                     /locus_tag="IVZ69_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HAP8184080.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            9829..10008
                     /locus_tag="IVZ69_002006"
                     /pseudo
     CDS             9829..10008
                     /locus_tag="IVZ69_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308695.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
     gene            10150..12231
                     /gene="cadA"
                     /locus_tag="IVZ69_002007"
     CDS             10150..12231
                     /gene="cadA"
                     /locus_tag="IVZ69_002007"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HAP8184081.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12542..14008
                     /locus_tag="IVZ69_002008"
     CDS             12542..14008
                     /locus_tag="IVZ69_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8184082.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4807 a         2518 c         3113 g         4096 t
ORIGIN      
        1 aaaaaagagg ttgtgacgtg gtcacgacct ctttttgacg attatgatac aaaaaacatc
       61 atttatgaac aaaatgtgaa taacgggcgt tcttgagata tgattttaat tgggaaaaac
      121 ttatcgataa ggaggtcttt atgaaaaaaa gactgttatg gtgtttgctg tttctatccc
      181 taagtttaac aagtcagcca gtttttgctg aagaaacaca gcggtctcct attacaggca
      241 cacgtctgta caaaaatgtt tatgtacaga caacagatct tgattctgcg attcctgaaa
      301 cagaagaacg gtctttgcag ccaagatttg gttacttttg gtactgtccg acctgtgatt
      361 atgaaagttg ctggcatttc ttacattcta cagctgcagc ttttgctttt actcatactc
      421 agaaatatga tggacatcat cctgttattt atgaggtata gatatgagca aaaaagaaaa
      481 actaatctcg ttgatcgtat tggtttgcct tgttcttctg gtaactgtca taggctatca
      541 gaaataccat gagaacatca gacctactaa agaatcttcc ccagcctcga ccgttgaaac
      601 agaaccgata agtagtcaga aagaataatt tttttagttt aaagaagaac atcagagcaa
      661 aaaaacacca actgaacaat atgtcgttta ttttaaaaaa agttcggttt ttcactttat
      721 gtaatcgctg agaaaacttt ttttaataaa aaaagtcgaa aaactctagc ttttttgtaa
      781 acggtatgat atactatagg agtagttttt gttcggtaat ctgtggtagc ttgtttcaaa
      841 taaacatctt ccagatatac accattcaag taattgcaaa atatgtgttg atacacaagg
      901 aggattttta ttatggaaac aggtacagta aaatggttta actcagaaaa aggatttgga
      961 ttcatcactg cagaaaacgg aaacgatgta ttcgttcatt tctcagctat ccaaggcgac
     1021 ggattcaaaa ctttagaaga aggccaagca gtaactttcg atgttgaaga aggccaacgc
     1081 ggacctcaag caacaaacgt tactaaagct taattaacct atactaaaaa ataaacgccc
     1141 agacatttgc gtgtctgggc gtttttgtct attttcttta aaaagcgatg agagtatttt
     1201 tctgcacttt gtagtataat ttcaaaagaa cattagaggc aggagaagag gaagatattt
     1261 tgaaaccaag aacttatgca gtcgttgata tcgaaacgac tgggacgaat ccaaaagaag
     1321 atcggatcat ccaatttggc tgcgtcatga ttgaatcagg tcggatcact tcacgttttt
     1381 cgatcgatat tcatccaggg cggaagattt caaaacaaat ccagcattta acagggatca
     1441 cgaatcaacg cgtccaaaaa gcgccttatt tcgaagatgt cgcccaaacg atttacaatc
     1501 ttttggcaga caccatattt gtcgcgcata atatttattt tgattataat tttttgaacc
     1561 atgaactcat gcgatgcgga cttcctagtt tgaagatacc aggcatcgat acagtagaac
     1621 ttgcacaaat tttcttgccg acggaaccaa gctttcgctt agctgatttg tcagaaagcc
     1681 ttggatttat tcatgagaat cctcatcagg cagatagtga tgccgaagtg acgggtcaac
     1741 ttcttttgct gatcgaagaa cggatgagaa aattgccaat catcacgtta gagcagattg
     1801 cgcgattaag tagacacaca ggtatggata cgagtcgttt catttatcat gtgattgaag
     1861 aaatgaaaga aaaaccagag ccacttgatc cctcattaga aatcgtcgat gggctagctt
     1921 tgcagaaaaa agaagtggaa ctattcacat ccgtccatta tggcgagcgg acatatccaa
     1981 gaaaaaaaca agcaaaagaa aaaatgtttg gtaaaacact gatgtatcga aaagaacaga
     2041 acagactgat gaatgcggtc tacgaccatt tcacaaaaga tgaatcaaaa gatttgatga
     2101 tcgaagcagc tacaggaatg ggtaaaacaa tcggttatct gctgccattg agttatttgg
     2161 ctacacctga aaaacccgct gtcatcagta ccgtttcgct agttttgcag cagcagatca
     2221 tagaaaaaga cattccattg ctgaatcaat tgctagatca gcccatacaa cctgtaatta
     2281 tcaaaagcta tcgccactat attgatttac agcgttttaa aggcacactt gtggaaccgc
     2341 cagaacaaaa acaatatgct ttgtatcaaa tggcggtctt agtttggctg acgcaaacga
     2401 agaccggtga tttggatgaa ttacatttaa caaatttgaa ccattcattc tttgcagata
     2461 tcgcgcacag aggtattgga tttttagcaa gaaatcagtc attttacgaa caagactttg
     2521 ttcgtttctt gcaaaagaaa atcaggcaaa gtaatttttt gattgtcaat catgcgtttt
     2581 taatacaaga aacacagcga aaagaaccat tgcttccagc tagtccattt ttgttgatcg
     2641 atgaagtaca tcatttgccg gaaatcgctg aaaaagtaaa tgacaaacga ttaagtatta
     2701 actatttcca taaacaaatc cagcaattag aagaaccaaa tcagctgttt gaccgaatac
     2761 aaagctattt accgaaagaa catgaagcct tacgctggtt atcgatttat cgagaagaac
     2821 tttctgcgct atgcgaagca cagatttgta tggcagaagg attaatgagt ttagtgagcg
     2881 gcaagcaacc taacggacag tatccagaag aagtcatgat gacaaaagag atgttggatc
     2941 agctgccact ggaatctggg acagccattg atcacctgca gcttttttat caggagatcc
     3001 agcagctaca gtcacaaatg cgtctgactt ttgagattat ccaagaaagc tggacaaacc
     3061 agatgcggat cgatttagca agtttatata gcttatttga tcaattagac aagcagtact
     3121 tgctgatgga tcaatggctg gaagactggc gagatcattt gatccattgg ttcgttcctg
     3181 ggaacacagc gcagcagatg atttttcatc tccatgattt tcaagcggct atgttgccgt
     3241 cgactgtttg gtatcctcga tatgatcgta ttctttatat tggaggaacg ctgaagatcg
     3301 gccctaatcg acactatctc tctaagcggc ttggcattga agcagcacct cttaaagtga
     3361 ttgcctctcc ttatgattat gagaaacagg caaggatcta tgtgccaaaa gaggcacctg
     3421 ccgtccatca agtcagcaat caagcatata tcgattattt agagacagca cttacaggtc
     3481 tgatcgaaca agaagatcgg ccaatacttg tgttattcac ttctcatgat gttttgcaga
     3541 aggtctatca gaaaatgcat ctgtctatgc tagaaaaagg acgagaaata ctagctcaag
     3601 ggtttggcgg aagccgggag aagcttttga aacgcttcat tttgtcagaa aaaagcgtat
     3661 tgtttggcgc tgacagcttt tgggaaggtg tagatttgcc tggggatgct ttgcagatcg
     3721 ttgtagtcac acgtttaccc ttcgataatc cgcttcgccc gatggtcaaa gctaggaacg
     3781 cttatttaga atcagagggg atcaatcctt tttaccagga atccgtacct aaagcagctt
     3841 tgaagttacg ccaagcatta ggtcgcttga taaggacgga gacagatcgt ggcgtattgc
     3901 ttattttgga tcgaagacta gtcactgcaa aatatggtgc acggatcatc catgcattac
     3961 cgaaaaaagt accgatcaaa gagctagcta tggaggaaat ctatcaggac atccatgaat
     4021 tcttaaagaa aaatgaagaa ggaagttaga ggagctgtct tttttcataa ttaaaatctg
     4081 ctataatgaa aaggaatgaa gataaaggag cgacgaccct tgaagaaaaa acagacaaag
     4141 gaaaaaacga ttaatcgcgt gttacttggc ttgatcgtat ttttattagc ggtcatcgtg
     4201 atcagctcga ttttttactt gcgttccagt cgtccggcgg tgcaggcgaa gaaagaagca
     4261 gtagaaatcg caaagaaata tgcaaatctt gaggaagccg atcattttta ttggtttact
     4321 cgaaagaaga catacttttc actgacaggt acaaatgata aaggaaaaga aatcgccgtt
     4381 atcattccta aatctggtga aaaagtaaaa gtattggatc aaacaaaggg actgactgaa
     4441 aacgaagcaa aacagacaat tgctgcggcc catcctgaaa tccaaatcga aaaagctgct
     4501 ttagggatgt atgatgatca gcctgtgtgg gaagtagtag gaaaagaaac aaatgggaaa
     4561 ctgaattatt acctgattgg ctttgaatct ggagatgaag tcaagacaat caagggaatt
     4621 taaaaggtaa aggaatgaat gggatggagt tatcaaaaag aacaaaacga ttagaaccgt
     4681 ctgtcacttt ggcagctgcg gcaaaggcca aggcattaaa agcaaaaggc agagatgtgc
     4741 tgagtttgac tgtgggagaa ccggattttg cgacaccaga aaacatccaa gaagcagcaa
     4801 tcgaagcaat ccgcaacggg aaagctagct attatacacc aacagcagga atcccagagc
     4861 ttcgacaggc aatcgttgat tatctgaaga aaaactatgg acttgtctat gaaccttcac
     4921 aaacagtcgt aacagacgga gcgaaatttg ctttgtatac ccttttccaa acgatccttg
     4981 acccgcaaga tgaagtcatc attcctgtgc cttactgggt cagttacggt gagcaagtaa
     5041 aactggcaga aggacttcct gtctttgtga aaggggaaga atccaatagc tggaaagtta
     5101 ctgttgaaca gctagaacaa gcacgttcag aaaaaacaaa agccgtaatc atcaattctc
     5161 catcgaatcc gactggaatg atttatagca agaatgaact gcaggcaatc ggtgaatggg
     5221 cagtaaaaaa tgatattttg atagttgctg atgatattta tggtcgttta gtttataatg
     5281 gcaatgagtt tactccaatt gcaacgattt cagaagcaat caaaaatcag actatcatca
     5341 tcaacggcgt gtctaaaaca tatgcgatga caggctggcg cattggttat gcggtgggaa
     5401 atcctgtgat catcaatgga atgatcgctg ttgcttccca gtcaaccagt aatccgacag
     5461 cagtcagtca atatgcagct gttgaagcat tgaaaggcga gcaagataca gtggaagaaa
     5521 tgcggaacgc ctttgaagaa cgcctgaata cgttatattc gcttgtggca gaactgccgg
     5581 gtgtttctct tgaaaagcca caaggagctt tttatctttt tcctaatgta aaagaaacgc
     5641 tacgcatgtg taaatatgaa aatgtcacac aatgggtaga agatctttta gaagaaacag
     5701 gggtagcgct tgtgactggc gaaggctttg gggcaccaga aaatgtccgc atgagttatg
     5761 ctactgatcg cgctacgtta gaagaagcgg tacgcagaat caagcaattt attgagagta
     5821 aaagtcaaaa ttaatcctaa agaaattcaa ggaatataaa aggagagtca tacgtggaac
     5881 aaattcaaat catcgattcg aaaaaccatg tgggagaaac agtaacaatc ggcgcttggg
     5941 tcgcaaataa gcgatcaagc ggaaaaatcg catttttaca attaagagac ggaacagcct
     6001 ttttccaagg tgtagttgta aaaagcgaag tgtcggaaga agttttccaa acagctaaaa
     6061 atctacacca agaaacatcc gtgttagtaa ctggagaaat ccgtgaagac agtcgttcaa
     6121 aatttggtta tgaaatcgga attacaaatg tggaagtggt aagcgagagc cacgattatc
     6181 cgatcacacc aaaagaacac ggaacagact tcttgatgga tcatcgtcat ttatggctgc
     6241 gttcttcaag acaacatgcg attatgcaga tcagaaatga aatcattcgt gcaacgtatg
     6301 aattctttaa tcaacatcat tttgtcaaaa ttgatccgcc gatcttgact ggttctgcac
     6361 cagaaggcac tacggatcta ttcgaaacaa attactttga tcaaaaagct tatttatctc
     6421 aaagtggcca attatacatg gaagctgctg ctatggcttt cggaaaagtc ttttcattcg
     6481 gtccgacttt ccgtgctgaa aaatcaaaaa cacgacgtca tttgatcgaa ttctggatga
     6541 tcgaaccaga aatggctttc actcatcaag aagaaagttt agaagtacag gaacaatatg
     6601 tagcattctt agtacaaaat gttttagatc attgcgaata tgcattagat gtactaggac
     6661 gagacaaaga agtcttaaaa acttatacaa aattgccatt ccctcgtatt acttatgatg
     6721 atgcgatcga attactgaag aaaaatggat ttgatgacat cgaatggggc gaagactttg
     6781 gttcacctca tgaaacgttc attgcgaatt cattcgaaca gcctgtcttt atcctaaact
     6841 atccaaaagc catcaagcca ttctacatga aaccacatcc aacaagagaa gacgtggtga
     6901 tctgtgcaga tatgatcgca ccagaaggtt acggtgaaat tattggcgga agcgaacggg
     6961 caacagacta tgatttcttg ctagaacaaa tccgtaatca cggtttggat gaaaaagaat
     7021 attcatggta tcttgatcta cgtaaatacg gttctgttcc gcactctggt tttggtctag
     7081 gtcttgaacg aacagtcact tggattgctg gtatcgacca tgtacgtgaa gctattccat
     7141 tcccacgttt gttgaaccga atttatccat aagaggtgat gaaaaagctg ttctgcatca
     7201 agtaattaga acagccaagc aaaaacagct gttcatgttt ttgaattggc gggacttatt
     7261 accgcagatg taagcttttg aataccgttt agtggagagg ttgtgaaaaa gctgtttagt
     7321 ttcgagtatt aagaaaaatt ttgtggaaat ggctttccac atttttgcat aaatttggct
     7381 taataccgag aaactggctt ttgaacaccg tttaaggaag aggttgtgcg cctgccgttc
     7441 agctccgagt cacaaggagt aatttcaaaa aacagttttt catgtttgat gactattgtg
     7501 acttgtgacc gaggagttgg ccggagagca ccgtttattc taaaaaagaa ctgcgaactc
     7561 tcgcagttct ttttttaaaa tacgggataa aggaagtttc cagcagacaa gagaagaaag
     7621 caaaagaaat tgctatttga ttcacaaggt tctataacga aatcgcaatc aatcaaacat
     7681 ttacaaagaa ggtaattcaa atggaaatct gatttgatga tgcttctgct gttgaaataa
     7741 agcagcatct agcacctgaa aacaaactaa tagtaacatt cgaagatgga gtaggtccgt
     7801 attttcagca tgcaataatc catatgtaag ttcaattcac ccttgaaatc atcggaccag
     7861 ataaagttat gaccaatcta tcccaagcaa tctagaagag atattagtaa agggacattt
     7921 actagaagtc ttagatgagc ctataaatat atgttctgat ggcgtcatca gtggtctgat
     7981 tgacggaagc ttaggtgtga tcgatctctc tggaccaaac aacgaaggaa tcaaggggaa
     8041 tccggcacgt taagaaaaaa atagcataaa aaactagaca cttgatgagc gttcattcaa
     8101 ttgtttgaag ggactaggct ggtgtcattt tttatacata tattttctct ttcgtcttga
     8161 tagggcttat gggataatat aaggaagaaa atcatcgttt tattcaaaaa ggagtttttg
     8221 acaaatgaaa aaacgtatat tatttatcgg tgatagcatt acagacgcag gaagagaccg
     8281 agcagaagca actgatctag gtaaaggtta tccacttttg attgccggaa aactaatctc
     8341 ccaatatcca acgatggaat ttgaatgcat gaaccgtggg ataggaggag acaaaattgc
     8401 agatctgcaa gtacgctggc aagaagattg tttagcttta caacctgact atgtatcgat
     8461 tttgatcgga atcaatgata cctggcataa tactagcgat caggctatat tcggaactga
     8521 gaaatctgct cagcaatttg aatccgttta tcgaaaatta ctaaatgaac ttcaaacagt
     8581 gggaatctgc aacatcatct tgatggagcc gtttgtactt cctataaccg acgaccgtca
     8641 tggctggcgt aaagacttag accctaaaat ccaaattgtt cgtaaacttg ctaaggaata
     8701 tggcgcattg ctggttcctt tagatggtat attcaatgct ttagggattg tttatggttt
     8761 ttcgaaatat acaagagaag atggggtcca cccaacgatt ggcggacatg agatcattgc
     8821 acaaagctgg atagatgcaa ttgccgcagt cgattttttt agtggagata aaaatgagcg
     8881 aaagaaaagt gagaaatgat ggaaatacgg tgggcagtaa aagaagatct acctcaaatc
     8941 aatcagctga ttactgatca tccagaatca ttcgtaaaag caaaaacggc agctgaccta
     9001 aatgataaga ataaactatt gctcgttgct gtaacaaaag aaaaacggat tatcggattt
     9061 gcgcaagcgg acgtgcaaca gtcagaagaa cgattggatc agcgaccatc aggaaaacta
     9121 atccaacaca cattagtaac aaaagaaaat acggaagaaa tccaaaaaaa atttgcagaa
     9181 tatttgatac tggaagctaa aaaaagaaga ataaaatcat tttttgccca gttttaatca
     9241 aaaacagtaa tagaaggaga aatacaatga gttgtttagg aaatgtcatc tggtttatat
     9301 tcggcggact aatcggtggt cttagctggt tagcagcggg gatactttgg tgtatcacga
     9361 tcataggtat cccaatcggt atgcaatgtt ttaagatcgc ctccctttct tttgcgcctt
     9421 ttggcaaaga agtaatttat caccagtctg gcatgtcatt gattgttaat atcatctggc
     9481 tgatcgtttc aggcctacca attgctctcg cacatgtcgt cagcggcatc cttctatgta
     9541 tcacgatcat agggatacct tttgccaagc aatctttcaa acttgctcga ttggcgttga
     9601 tgccattcgg tgcagaaatt gtataaaaga gaataataaa ggttagataa agcatagagt
     9661 caggtgggat acatgtattt cacctgactc tatgcgttct cctgtataag ttcttccatg
     9721 tgacttttac gtcttttatt tatatggggt tactgtttat ggaaagttga aataattttc
     9781 attaaagaac tctttctata tttttgaaag cgtagtggag cttcgaatat ctgggaagga
     9841 cattttgcag ggattgaaaa aagatattgt cctatcgaaa aattaatgaa tttagacaaa
     9901 ttgccagcaa caggcttcaa acttagttgc tatcctgtca agatcaagaa ggcaagtgcg
     9961 ggttggataa gagcagtggc aatgatcgaa aagaaaaaga aagaataagc caaaacatct
    10021 gtatggaaga aattttccga tgcagatgtt tttcattttt tctttcggat accttgacat
    10081 atgaataacc gttcatttat aattagttat gaagagatat tcatatgttg aggcgaggag
    10141 gtcattaaaa tgaaaagtta cagattagaa ggtttagatt gtgcgaactg tgcaatgaaa
    10201 atcgaaaaag gagttcagaa gatcaatgga gtcaaggaag caacggtaaa cttcacttct
    10261 ggaaaactaa cgattgacgc agaggaagat catttggcta cgattgaaca agaaataaaa
    10321 aaagtagtga aggaattaga accagatgtc aaagtaacag aaatagataa ggaaaaagta
    10381 tctgaacatg gaaatgaaaa agagagaaat acgctgttcc ggattttatt ttcccttgca
    10441 ggtatcgctt tattgctatt atttgatttt aatgaaccaa ttcgcttgat agggtattta
    10501 ttgatttatc tgctgatagg atatgatgta gtgaagaagg cagtgatgaa tatcgtcaaa
    10561 ggaaaaatct ttgatgagaa ttttcttatg tctgttgcta cgattggcgc tatgttgatc
    10621 ggtgaatatc cagaagccgt agcagtgatg ctattttatc aaatcggcga gtatttccaa
    10681 ggattggcag tcagtcattc aagaaaatcg attcgcgaat tgatggcgat ccgtccagaa
    10741 acagctcacg tgcagacgac ggaaggattg atgaccgtga accctgaaga cgtgcagatc
    10801 ggtcagtttg tacttgtgaa gcctggtgaa cgtgtaccgt tagatggaac gatcatcgaa
    10861 ggagaatcat tagtcgatac gtcagcactt acaggagaat cagtccctaa atctgtatat
    10921 gttggtgaaa cagtattaag tggatttatc aataaaaata aaccattttt agttcaagta
    10981 gaaaaatctt atgaaaattc tactatcagc aaattattag aattagtaga aaatgccagc
    11041 agtaaaaaag caccagctga aaatttcatt actaaattcg cgcgctatta cacaccagtc
    11101 gttgtaggat tggccgtttt attagctgtt ttacctccac ttgttgtttc tggagcggcg
    11161 ttttctgaat ggatctatcg agcattgaca tttttagtga tctcatgtcc atgtgcatta
    11221 gtgatctccg taccccttag tttctttggc ggtatcggag gagcaagtaa aatcggtgta
    11281 ttagtaaaag gttcaaatta cttggagttg cttgcacaaa ctgagacagt ggtattcgat
    11341 aaaaccggca cattaacgaa aggtgacttt tcgatccaga cgatcgatac aaaaatcgat
    11401 ccaaagatat tcatgcaata tgttgcgagt gcagaacagt tttctacaca tccgattgct
    11461 caatctgttt tagaaggcta cgcaggtccg cttttaccaa cagctaatat ccaagaattt
    11521 gcaggtgaag ggatcttagc tgaagttgat ggcaaacaag tattagcagg taatcacaaa
    11581 ttgatggaaa gatttgaaat ctcttttcct tcaagtcaag aaatcggtac attgctttat
    11641 ctagcgatcg atcaaagtta cagtggttat cttgttattg cagatacctt gaaagaagat
    11701 gccgtagacg cattggttca attaaaaaag gctggtgtga agaacacagt catgttgacg
    11761 ggcgattcga aaaaaattgc tgatcatatc gggaagcaag taggcgtgga caagatatat
    11821 agcgaattgc ttccagaaga taaagtgcag cggttagagg aaatcttaca aagaaacaat
    11881 aaaaagaccg catttgtcgg agatggaatc aacgatgcac cggtgctagc aagagcagat
    11941 gtaggaatcg caatgggtgg attgggaagc gatgctgcaa ttgaagcagc agatgtagtc
    12001 atcatgaatg atcaaccatc gaagattgca gaagcaatcc atttagcaaa gaaaacattg
    12061 aaaatcgtca aacagaacat tgtctttgct attgggataa aaattttggt acttgcctta
    12121 ggtgcttttg gttttgcatc aatgggagat gcagtatttg cagatgttgg ggtgacagta
    12181 ttagctgttt tgaatgccat gcgaagcttg catgtaaaaa ataaacgttg atcaatgaag
    12241 aggacgaatg aacgtcctct tttttttata tccttttctt aatgaaaaat gtaaagaaaa
    12301 tagataggat tataaaataa ctaatgtttt taattttgca gaaaattcaa aatagcttga
    12361 aattcaataa ggtaaatgaa ataaaagaaa ataacttatt tttttgatgg aaaaaatatg
    12421 aaaaaacgat gtgtattaaa taaaagaata cacacataaa ataacactgt cttgtaagtt
    12481 tgttaaaaat tgaatatgat tacatctgga taacaaattt ttatcataaa ggagagaacg
    12541 aatgaacaac aaacaattac gctggtttac tgttgcgtta attgcattta acatggtttg
    12601 gggcatgggg aatgtagtta ataactatgc tcagcaagga gtatcagttg tcacctcttg
    12661 gctattgatt ttggccattt attttattcc atacgcattg atcgttggac aattagggtc
    12721 agccttcaag gatagtaaag gaggcgtcag ttcatgggtc gaaaatacga catctaataa
    12781 acgactggca tactatgccg cttggactta ctgggtcgtc catattcctt atttggcaca
    12841 aaagcctcaa gcaatcctga ttgctggcgg ttgggcagtc caaggaaatg gaaatatcgt
    12901 aaatacgatg tcagtacaaa tggtagcagt tatttcactt attatatttc ttgccttttt
    12961 atatttatca acaaaaggac tttctacttt gaaagtgatt ggcggactgg ccggaacagc
    13021 gatgttcgtc atgtcgatct tatttattct tttagctgta acggcaccgt tcatcaatcc
    13081 aacgatggaa tttgccacac cacatatgaa tcaagtgaaa acatatattc caacatttga
    13141 tttcagttat ttcacaaccg tttcgatgct agtatttgca gttggaggag cggaaaaaat
    13201 atccccttat gtcaactcta caagaaatcc tgcaaaggaa tttcctaaag ggatgatctt
    13261 cttagcagca atggtaggga tttgtgctgt attaggctca gtcgcaatgg gtatgctgtt
    13321 tgctagcgat aatattccta aagacttgat ggcaaatggg gcatacagtg cttttcaaat
    13381 tttaggtaat tactatggta tcggtaactc attgatgatc atttacgcat tgacaaacat
    13441 gattggacaa atctccgcat tagccttttc aattgatgca ccactaaaaa tcttgttagc
    13501 agatgcggat ccagaatttg taccaaactg gctacgtaaa cgtaatcgta aaggtacatt
    13561 ggtgaatggt tatcttctga caggtatact agtaggaatc attattttgt tgccgatctt
    13621 tggtatcaaa gatatgaatg aattagtaaa atggttgacg aacttgaact cagttgtcat
    13681 gccaatgcgt tacctatggg tgttcttggc atatatgatg ttgaataaag cttataagaa
    13741 attcaattct gaatataaat ttgttaaaaa tccaaaaatc ggttttatct ttggtgcttg
    13801 gtgctttgcc ttcactgcgt ttgcatgtat cctaggaatg gtgccaaaag tagattatac
    13861 tgctgatcct aaagcatggt ggttccaatt attcacgaat atcatcacac caattgtctt
    13921 gatcttatta ggtatgatct tgccagcaat tgctcgtcga gacaaaaaca aagaaatcac
    13981 tgaaccagaa acagtggttc agccttaaaa tagaaatact tgttacaaga ggttgtgaca
    14041 gaagtggtca gcttcaagaa ataagaagga atttacgaaa attgcttctc aaatttttgt
    14101 gaagtttcgg cttgtttttc gcagaagcta cttctggaac accgtgaatc agaggttgtg
    14161 aaaaagctgt cctgcatcaa gtaataagaa cagccaaaca aaaatagccc ctcatatttt
    14221 tcgttttgct gggcttatta ccgcagatgc aagcttttga acaccgttta agaaagaggt
    14281 agtgagcctg ccgtttaact ccgagtcaca aggagcaatt tcaaaaaaca acttctcatg
    14341 tttgttgact attgtgcctt gtgaccgagg tgttggcagg agaacaccgt ttaaggaaga
    14401 ggttgtaaaa tcagcgattt gacctgagta ttagaggaac aaacgaaaaa atagctcctc
    14461 atattttgcc gttttttgag ttaatgctga aggtcagctg attgaacacc atttattcga
    14521 aacaagggac tttg
//
LOCUS       DACDAF010000070        14118 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.071, whole genome shotgun sequence.
ACCESSION   DACDAF010000070 DACDAF010000000
VERSION     DACDAF010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.071"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..556)
                     /locus_tag="IVZ69_002009"
     CDS             complement(<1..556)
                     /locus_tag="IVZ69_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HAP8184083.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGA"
     gene            complement(572..1051)
                     /locus_tag="IVZ69_002010"
     CDS             complement(572..1051)
                     /locus_tag="IVZ69_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HAP8184084.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKARLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(1057..2081)
                     /locus_tag="IVZ69_002011"
                     /pseudo
     CDS             complement(1057..2081)
                     /locus_tag="IVZ69_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
     gene            complement(2098..3204)
                     /locus_tag="IVZ69_002012"
     CDS             complement(2098..3204)
                     /locus_tag="IVZ69_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HAP8184085.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="IVZ69_002013"
                     /gene_synonym="adhC"
     CDS             complement(3433..6030)
                     /gene="adhE"
                     /locus_tag="IVZ69_002013"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HAP8184086.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="IVZ69_002014"
     CDS             complement(6335..6715)
                     /gene="yajC"
                     /locus_tag="IVZ69_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HAP8184087.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="IVZ69_002015"
     CDS             complement(6812..7957)
                     /gene="tgt"
                     /locus_tag="IVZ69_002015"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010769586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HAP8184088.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            8175..8873
                     /locus_tag="IVZ69_002016"
     CDS             8175..8873
                     /locus_tag="IVZ69_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HAP8184089.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(9041..11680)
                     /locus_tag="IVZ69_002017"
     CDS             complement(9041..11680)
                     /locus_tag="IVZ69_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP8184090.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(12299..13330)
                     /gene="queA"
                     /locus_tag="IVZ69_002018"
     CDS             complement(12299..13330)
                     /gene="queA"
                     /locus_tag="IVZ69_002018"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HAP8184091.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            13523..>14118
                     /locus_tag="IVZ69_002019"
     CDS             13523..>14118
                     /locus_tag="IVZ69_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005232177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8184092.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEA"
BASE COUNT         3959 a         3096 c         2543 g         4520 t
ORIGIN      
        1 aagcgcctac gagataacct cccataaaca aagcagagat cgaagcacca ccagcaacaa
       61 gtgaatacat gataaaagca gtacttggag gaatgaccat acctgtcgga gctgacgcga
      121 tattgaccgc tgtcgcaaac ttccggtcat atccttcttc cacttgctga gggatcaaca
      181 ctccaccaat cgcggtagaa gcggcaatgg ccgagctaga gatggaacca aataaagcat
      241 tccctaacac attcgtatga gccaaagccc ccggcacgcg cccgacgaac aacatcgcaa
      301 aatccactag tttcttagct atccctccat tattcatgat aatgcccgag agaacgaaaa
      361 acggaatagc gatcagcgaa aaactattga tacttcccac cattttttga gctgaactaa
      421 aagcagaaac atcaaacggt ataactaaca ataaagtcat catcgatgag aatgcaatac
      481 ttatagcaat cggcatccct aatacaagca acacaacaaa tacaaaaaat aacactaatc
      541 cggcttctat tgccatttta ttcctccatt tttatatttt ttcttgaatt gctggcttgt
      601 tgcttaatgt atcgattaga ttgatcaggc tatagataat gatgagtacc cccgatacag
      661 gtactgacag ataaacatat cccataggaa tacttaaaga aggcgagatc tgccccattg
      721 tcaatgtgac agcattccat ccgccataca ccatgatcat cgcagcaaat accagaaata
      781 aactttgaac aacaacttct aaaattttac tttttttgcc agttaatttt tcacttaaaa
      841 ccgttacggc taaacgtgct ttttgtccca caacatacgc ggaagacaac atggcaaacc
      901 agacaagacc gaatcgaaca agctcttccg tgaccgtatt tggatttcct aaaaccgttc
      961 tggaaaatac ttgccataaa acaacagcga ccatcccaac aagcaaaaca gctcccagga
     1021 tctctaatac cttgtttaaa atcattttca ttacagctac gctccttgct cttggatctt
     1081 ttgataaagg tctttgtagg taggatcgtt tttgaatata tcatgaagtg gggcaactgc
     1141 ctctcgaaac ggtgtattat ctacatcatt gaattggact ccatgttctt cttgtgctaa
     1201 agctttttct tcttcaattg cttttgcaaa agcttcaatt tcaaaaaccg ttgattcttt
     1261 cgctgcttct tcaatggctt tttcctgttc atcagttagc tgttctttga tggcatcatt
     1321 catgatgatg atatctggca cacgtgtatg ctcatcatag gaatagtatt tagctacccc
     1381 gccatgtcca gctgtataca agacaaattc attgttttct gatccgttga tcaaattgga
     1441 ttgaagagac gtgtacactt catcacttcc cataggtacg ggcgaaccgc ctaaaagctc
     1501 taccattttg atagcggttt cgctttgcat cacacggatc ttctttccct tcaaatcttc
     1561 cggcgtatgg atcggaccgt ctaccatata aaagctgcgc tgaccagaat cataataggt
     1621 caatccggta aatcctaaat ttttggtcga ttggtagatt ggctccatta tttcttcatt
     1681 atccatcacc ttaaagaaat gttcttcatc attgaataga taaggaacgg aaaaaatcga
     1741 ataatcttta gagaaacttt ccaacgctga ggcacttact tttgtgaaat ctactgctcc
     1801 tgactgtgtc aattcgatca gttcacgttc tccacccagt tgtccatctg ggaaatactg
     1861 gatctgtacg gaaccatctg ttttttcttt tactaaacgc ccaaattcat tcattgcatc
     1921 aattactggc tgttgcttgc ataagcaaag cgcaaggtaa ctatctcatt tacgtctgca
     1981 tctgcgacag ttgccacact agaattattt ccgcagccgc ttagacctag cagacctagg
     2041 ctaagcgaac ttgctgcaaa cagcagtgat gtttttttca tatgggtttc ctttctttta
     2101 acaataagag acgagcaatt ctgtcaaaca aagcaccgtt aacgactgtc cataaggcat
     2161 tgctgtgatt ccgatattcc gataaaaatc taaactgtcc cccattcctg tcccgattga
     2221 aacgttttga acttctcctt tttcatcgat ttgttcaagc aatccttgga tagcacgata
     2281 agcgacttct ttatattctt gtggtaaata acgtttatgg accgctttca aaataccgta
     2341 agcaaatcct gcagttgcag aagattctac gtaagaagaa ggatcatcca acaacgtatg
     2401 ccataaaccg ctttcagact gataagtttt taatgcacgc acttgtgctt caagtgtttc
     2461 gatcaataat ttgcgcaatg catcttcttt cgataattct aagatttcaa tgatctctgg
     2521 aatagcaatc gtcaaccagc agtttccacg agcccaaaat gcttcggcat agttatgatt
     2581 tccttcaaac gtccagccgt gataccacaa tcctgttcgt ttatccatca agtatttgat
     2641 atggatcata aactggtaac gagcttcttc taaatattct gggcgattca acagtttccc
     2701 gatttttgcc aaaggaagca ctgtcatcat caatgtatcg tcccacaact gattcttatt
     2761 ttccggtcca tatgtggcat gctgtaaccc gtcttcattt gtccgaggca tgtcattcat
     2821 gacccattct gcccattgtt ctaaataagg caaatagcgt gaatctttcg tgtcttcata
     2881 caagtaagcc atagtcaata gcggtgccat tgtattgacg tttttgggcg gagcgccttc
     2941 ttccatacga tcctcaaacc attcattgac cacttgataa gcgcgaggat tttttgtcat
     3001 ctggtaattt ttataaatac catatagacc gacaccttgt ggccaattcc acactgtcca
     3061 gcttttgtca tctactttca gtccatcaaa gtccaacaaa aattcaccat tatcgtcttt
     3121 gatcgttgtc aggttttcaa cgagcaggtc aattttttct ttcactaatt ctttaggtac
     3181 aaaaatctct tctttaataa tcatctttac gccacctttt taaacgcttt cattttatat
     3241 ccttaatata gcagtaatac cgtccactat aaatatcgct ttttgaacaa aaactgtcta
     3301 aaattgacct aaatgttaaa taacaaaagt aactttcagt tacttggaaa ttaaaaaaag
     3361 aacttggaga aacaacgttt tccaagttct ttttcatcta ttttcttatc ttttttctac
     3421 gctttctttt gcttatccgt tgtaagcatc aatgatgatc tgtttcaatt cagagatcaa
     3481 tggttctttc ggattagctg tcgtacattg gtcttcgtaa gctaattcag ccatacggtc
     3541 tacggttgta tctagtgttt cttgtgtgac tccttgagct tttagactca tgttgatgcc
     3601 gacagatttt cctaattcat aaacagccgt tgctaaagct tcgactaatt cctctgttgt
     3661 ttcgcctttc agacctaaga attttgcgat atctgcgtaa tctgtatctg cacggaaata
     3721 gtcatattta gggaacatcg catgtttttg tggatctttt gcattatagc ggataatatg
     3781 cggtaaaaga atcgcatttg tccgtccatg agggatcccg tattccccgc cgattttatg
     3841 tgcgactgag tgacaaatac ctaggaatgc gttagcaaac gccataccag ccattgtaga
     3901 agcgttgtgc attttttcac gtgattccat atcaggtgtt tttactgatt tttctaaata
     3961 gtcaaagact aacttgattg cttgtaggct caatccacgt gtataatctg aagccatgac
     4021 tgaaacatag gattcgattg catgtgttaa cacatccatc ccggtatctg ctgtgacaga
     4081 tgctggaact gacatgacga attgaggatc gacgattgcg acatctggcg tcaatgcata
     4141 atctgctaac ggatatttca catgtgtttc actgtcagtg atgaccgcaa atggcgttac
     4201 ttcagaacca gtccctgatg ttgtcgggat acatacgaat tgtgtttttt ctggtttgtc
     4261 gatcttatat gtccgtttac ggatatccaa gaatttttgt tttgcaccaa agaaagatgt
     4321 gtctgggtgt tcatagaaca tccacattcc cttagctgcg tccattgcag aaccgcctcc
     4381 aagagcgatt actgtatctg gcttgaagtc tgccatcagt ttcgttcctg cgtatacggt
     4441 atttgtcgat gggttcggtt caacatctga gaagacttcg atcttcacat catttttacg
     4501 tcgtgccaat acttcacgaa ctgtatcgca gtaaccgaat tggaccatac cagggtcaca
     4561 aacgatcatg acacgttcaa cgttttccat tttctctaag tacaatagag agttcttttc
     4621 aaagaagatt tttggcggta atttgaacca ttgcatgtta tttctccgtt tcgctacagt
     4681 tttgacattg attaagttta cagcagagac gttacgagaa acagagttct taccataaga
     4741 accgcatccc aaagtcaatg acggaatcat ttcgttatag atatcaccga tgccgccttc
     4801 tgcagatggt gtattcacta aaatacgaca agctttcatt cgaagaccga atttgacatg
     4861 caactcttcg ttttctgaat ggataactgc tgtatgtcct aatcctccaa gattcaacat
     4921 accttcacac aaatcaaacg catggtccgt gttgttagct ttgatcatgg caagaactgg
     4981 agaaagtttt tctcttgata gcggataatc tgggcctacg ccttccaatt cagcaatcag
     5041 cattttcgtt ccttttggta cactgattcc tgccaatttt gcgatttcca tcgcagaatg
     5101 tccaacgatt gatggattga ccgcatattt tccttcgttc atcactgcat cttctaattt
     5161 ttgcaattca tctggtttta cgatataaac ttggtgtgct tggaattctg cttttactgc
     5221 tgcatagatt tctttatcca cgatcacagc ttgttcagaa gcacaaatca ttccattatc
     5281 aaatgttttc gaaacgatca aatcgttcac tgcacgttta atttttgctg ttttttcaat
     5341 ataagctggt acgttacctg gacctacacc taaagctggt tttcctgtag agtaagcaga
     5401 cttgaccatt ccagctccac ctgtcgctaa gacgatcgcg atacctggat ggttcattag
     5461 catagaagtc gcttcgatcg aaggatgttc gatccattgg atacaatttt caggagctcc
     5521 ggcagcgata gcagcatcac gtaccactcg tgctgcttct gcagaagatt tttgggcact
     5581 tggatggaaa gcaaaaacga ttggatttct tgttttcaac gcgatcattg atttgaaaat
     5641 cgttgtggaa gtcggattcg ttgttggagt tactccgcaa accacaccga ctggttcagc
     5701 aatttcaatc aacccttttt ggacatcttc attgatcaca ccaactgttt tatcatgttt
     5761 gatattatgc caaatatatt cggacgcata catatttttg attgctttat cttcgtaaac
     5821 accgcggcct gtttcctcta cagccatctt cgctaatggc atatgttgat ccaaagctgc
     5881 cattgccatt tcatgcacga tatggtctac tttttcttga tcaaagcttt ccatttcttt
     5941 caatgctgca tttgcttttt ctgccaaatc atcaatcatt gcttgtacgt caattgtctt
     6001 cgttttttct ttttctatta ctttagccat cattatcctc ctaatgggtc atggttattt
     6061 gttaaataat tcacatgtat atcatacaat atttattttt ctatgtaaac acttttttgt
     6121 gatttttttc acagttattt ttaaatataa aattgcttta tttacaggtg tttgtataga
     6181 aaaatatata aagttattta ttattattta tatgacacac ccgattattc aatattgagc
     6241 aatatatccc atgctcttat ctctttcttt tttgaataaa aaatgaggta ggacatcttt
     6301 ctgccctacc tcgtctttaa ataagctttg atacttattt ttcttccttc tcttctgtct
     6361 cttccagcgt ttctgttgtt tcagttttta cttcaactgt ctcagctggt tcttctgttg
     6421 tttcaacagt agtcgttgca tcatttgtta cgacagtccc tggtttgacc gttttgattg
     6481 ctgcacgatc gtactcaagg aagatccctt cgcagtctaa aacaactgtc cgtttgtcat
     6541 tgtcgatttc tgaaacaact ccatgtaatc cgccgatcgt tacgactgaa tcacctggtt
     6601 tcatgctatc taacaagttt tgacgttctt gctgttgttt cttttgcgaa cgtgacataa
     6661 aaaaccacat tgctaatagc gcgataaaca tcacaagcat tggtaatgtt cccatttttt
     6721 tcacctcact aattctgtat ctacaaaaaa cactttagca gaaaaatgct gataacacta
     6781 gttttttact taatttttaa aagattttcc tttagaagct ttttgcgttt tctttattga
     6841 acccgtattc ttcaaaaaag gcttctctaa attcaagcaa attatcatcc atgattgctt
     6901 gacgtacttg tttcattaga ttcaacaaga agtataaatt gtggtaagaa gtcaaacgaa
     6961 tcccaaatgt ttcatcacat ttgatcaaat ggcggatata ggcacgtgta tagtttttac
     7021 atgtataaca atcacatttc tcatcaattg gacggaaatc atgggcatat ttcgcatttt
     7081 tcactactag acggccttga gaagtcatac atgtgccatt tcgagcgatt cgagtaggca
     7141 agacacagtc aaacatgtct actccacgga taacaccatc gatcaatgaa tcagcagcac
     7201 cgacacccat caagtaacgt ggtttgtttt cggggatcaa cggtgtagtg aattctaata
     7261 cacgattcat ttctgattta ggttccccga cagataaccc gccgattgag taaccaggga
     7321 aatccatccc gactagatct ttcgcgcttt gacgacgaag atcttcaaac cctgctcctt
     7381 ggatgattcc aaataatcct tgacggtctg gattagcatg agctttcaat cctcgttctg
     7441 cccatcgaga cgtacgttct actgattttt tcacgtagtc gtaactttca tcgaatggtg
     7501 gacattcgtc aaaactcatc atgatatcag agcccaattt attttggatg ttgattgctt
     7561 tttctggtga taaaaacata cgcgaaccgt tcaagtgatt tttgaaatgc acgccttctt
     7621 cttcgatatt ccgcatatca cttaatgaaa aaacttgaaa gccgcctgaa tctgttaaaa
     7681 tcggttgatc ccagttcata aatttatgca gtccgccagc ttcttctact aagtcttcac
     7741 cagggcgtag ccataaatga tatgtattac ttaaaataac gccagcaccc atttctttca
     7801 actcttctgg ggacattgtt tttactgtag ctaatgttcc tactggcatg aacattggtg
     7861 tggggaaagt tccgtgtggc gtgatcaatt cccctaaacg cgcgccagta tgtttttctt
     7921 tcttgattaa acgatagcga atggcaggtt gcgtcattca tttccctact ttctatataa
     7981 aatatcttga caactcccac catcataatc gtttcaagtg ctttttgcaa gttccctcgg
     8041 cttccttcta ctttatttaa tattcttttt tttatccttt ttttatgaat aacaaaaaaa
     8101 agaaaaacat tatgacagaa atattttttg atacatggta tattggtgtt attaaagaaa
     8161 aggagggaaa aatcatgcaa tcttctgcag aattaaaacg ccaagcaaaa gagagtctaa
     8221 aaggacgttg gggacaagct gttttactaa atctaatccc tacattgatt ggtattgcta
     8281 ctattcttct tattatgatt cctattatct tgtttgccac caccatatat gatggatcag
     8341 cgagcgtctc agaagcgaca acttcaggag gcggtagttc aggaggcggt ggcggaatta
     8401 tttccagcat cattagcgct ttgttcatga gcggtatttc ttggacttat cttgatattt
     8461 tacgtggaca aaaagatcag atcgaaccat tcaaagatgc atttcgtgga ttcaaaggtt
     8521 tgtttatcgg cggagtgatc agcttagctg tgctgatctc gatctttaca acattatggg
     8581 gtttgctatt agttattcct ggaatcatta aaagctattc ttattctcaa agctatttta
     8641 tttactacga tatcgtccaa gaaacaggac aaacacctaa agtactggat acgatcactg
     8701 caagtcgaaa attgatggat ggttataaag gacaactttt ctggttagat ctttcattta
     8761 tcggctggca tatcttagca ttagcaactg ctggtattgg ttatctatgg ctcagcccat
     8821 acatttctgc aacaaaagca gcattttatg aacaattgcc aaaagatatt taaaagagag
     8881 tgtgacttgt gaccgagggg gtggcaggag aacaccgttt atcgagaggc agtaaaagaa
     8941 acattcagcc cattagcaaa aaggaggtgt gacaacattc atgtcacacc tcctttttgt
     9001 atagttccag taaaaagaaa atcaacttag aaacagttaa tcattcctct tcttctgctt
     9061 ccggtaatcg atggaacttg atcagttcat tcaccgcgat tggtacgata gataaaatcc
     9121 ctaccaagaa ccagtgattc aaactgatgt gtactaggcc gaatagttct tgcgtaaatg
     9181 gcagcaaagc aacagccgtt gtaatagcta atgccagtaa cgccatttct accaaagctt
     9241 tattggtcgc taaattgact ttgaagatcg attggctgct gcgtacattg aacacatgca
     9301 gaatcgatga ataagctaag atcaagaatg caacagtttg accgacatgc tgacttgcgt
     9361 ctacccatgg gctgatagta tcgacataac tacctaaata ataaccaaac aaggttacga
     9421 tggtgaagac ccctgcattt atggcaattt tttgcaataa acctcgagca aagatccctt
     9481 catttttcgg aatgggtggc tgatccatga tgccgtgttc cgctggctct cttcctaaag
     9541 caaatcctgg aagtccatca gcaactacat tgacaaacag tagttgcaca gctgtaaatg
     9601 gtgctcccca tcctaacagc atcgcaatca aaacaataaa gatctccgaa atattacagc
     9661 ttagcaaaaa gttgatagct ttacgaatat tctgataaac cgaacgtcct tgactgacag
     9721 cgtctacgat cgtcgcaaag ttgtcatccg tcaaaatcat atctgcggca ctttgcgcca
     9781 catctgttcc tgtgatcccc atggcacacc caacgttact tgctttcaac gctggtgcat
     9841 cattcacacc atccccagtc atcgctacga ctgcacccgt acgttgccaa gatttgacga
     9901 tccggatctt gtcttctggc gttacccgag catagacaga gagagctttg acacgcgcat
     9961 ctaattcttc gtctgataat tgatgcagtt ctgatcctga aagtgcttct gacggatcat
    10021 tcaagatacc taattctttc gctatggcac tggcagtcac cacatgatct ccagtgatca
    10081 tgactgtttt gatgccagcc tttttcgctc gcttgattgc tcctttactt tctggacgtg
    10141 gtggatcgat cattccgatc agaccaatca aacgtaagtc tttttccagt gcttcagaag
    10201 aaatatcttg cggttcttcg tcataagtag cataaccaac agcaatcact ctcagtgccc
    10261 gtttaccaaa gcgatcatta acgatcgccg cttgttctac atcgcctgaa ctaaagcgcg
    10321 gagcaagaac atcgaatgct cctttggtga ttgagatgta tttttcgccc atttggtgaa
    10381 ctgttgtcat catttttcgt tcagaatcaa aaggaagctc gtttactcgt ggatattttt
    10441 cttctaattc tgcctttgta tgataattct cttcaacagc ccttacgatg gctacttctg
    10501 ttggattacc tttgataaca aggtcgtcat cttcttgctc gaccgtcaca tctgtacata
    10561 gtgcagccat tttcaatatt tccatcgcgc tgttcgtcat tgaatcttcg atattcgtta
    10621 cttcatcttc tttgctccat acccggcgga cgcgcatttc attttgtgtc agcgttcctg
    10681 ttttgtctga gcagataaca ttagcggttc ctagcgtttc aactgctggc aactgtcgga
    10741 tgatcgcatg tttcctcgcc atcttctgca caccgtatgc aagtgtcaac gtaacaataa
    10801 cagtcaaggt ttccggtaca gctgcaacag ccaaggaaat cgaagtcatg aacatctcaa
    10861 ggagtggttc tccttgcagt tcaccaatca caaatactaa agccgcagcc gctaaagcga
    10921 tcatactgat tcgtttgcct agctgattca atcggacctg taaaggtgtt ttttgcatag
    10981 tattttcgtt caaaagatcc gcgatcttac ccatttctgt agccatgcca atggcagtga
    11041 cgatcgcttt cccacgacct gcagcaaccg tacatccttt aaataccata ttaagttggt
    11101 cacctaatga ctcatcttct tcagcaataa atgctgcatc tttttcaact gcttcacttt
    11161 ctccagtcaa cgccgattct tctacacgta attgtgatgc ttcgatcaaa cgggcatcgg
    11221 cagaaatagc atcaccggac tctaaaacaa gaatatcacc cactaccagt tgctctgact
    11281 caacagtggt cactttgccg tctcgtatga cagttgccgt ttgtttattc atatcttgca
    11341 aggattccag tgctttttct gcgtttcctt cttggacaat cgccaatacc gagttgatca
    11401 caacgatagc gatgatcagc agtccttcaa ataaatcccc atgttctgta gcaaatgcgg
    11461 tataaaagga aatcaccgct gctacaagaa ggatgatcgt tgtaaaatcg gacaagcttc
    11521 gaaagaattt tttgatcatc gattctttcg gcgcctcatc gaatttattc aatccctgct
    11581 tttttcgccg ttcatccact tcttgtgaag acaacccagt atctggatct gcttctgtta
    11641 ccttctttac ttcttctatt gtctgcttgt attcttccat cctattcctc ctttaaaatc
    11701 ttcgtacaaa aaaaggtact tattttacta taacatcctt tttttattta cttcaaataa
    11761 agggcttatc gattatttgt taagaaagcg taaaatttaa agtgcttata tttgcaaacg
    11821 ctaccaaagg atgctattat atagatgtaa ggaaggagga taccatcaaa tagacagaag
    11881 aatttctcga tagaacagtg taagcaaaca aagttgttag aagtacaggt ttcacccaga
    11941 catgcgtgta gagtacaaac ctataaatag tgaatgcgta tggatgtttg gatcacgaag
    12001 tatccgaaac aagaagtaat gcgatacgta acaattgaat aacgtaaacg tctgaaaatt
    12061 gaataggaac aagagatgtt tcaaatgttg aagatgtaac gaaaacaaaa tttttgttta
    12121 acatgaagaa attcaacacc gtgctttgca tgtatgatgg aaagttacaa tcatttctgt
    12181 ttatttgaat ccttccgagg tacaagaaag ccgagcttat cgagagctcg gctttttctt
    12241 tgtcataaaa tctttgtaaa gcttttttgt tattcaaaac tagcggcttt tcataacctt
    12301 atttcacgaa catcgcatct ccaaaactaa agaaacgata gcgctcttca atcgcatgct
    12361 ggtaagcaga taaagtcaat tctcttcctg caaaggcact aactaacatg actaaagtcg
    12421 attttggcaa atggaaatta gttgagaaag cttctaccac tttgaattca tagccaggcg
    12481 taatgaaaat atcagtccat ccgctgtctg ctttgatttc tccattaaat ttcgttccaa
    12541 tcgtttctaa tgttcgaatt gaagttgttc cgacagccac gattttcccg ccatttttac
    12601 gtacttggtt caatcgctca gccgcttctt ccgtcaaacg gtagaattca ctatgcatat
    12661 ggtgttcttc aattttatct acgctgacag gtcggaatgt acctaaccct acatgtagtg
    12721 tcagatagac taattcaaca ccctttgctt cgatctcatc aagtaattct ttcgtaaaat
    12781 gcaatccagc tgttggcgct gcagcagaac cattttcttt cgcatagaca gtttgatagc
    12841 gatctgggtc ttccagacgt tctttgatat atggaggcaa tggcatttct cccaatgatt
    12901 caagaatctc tagaaaaatt ccttcatact caaagtcaat gatccgtccg ccgtgttcca
    12961 attcttcttt cactactgct tgcaatctgc catcaccaaa agagattctt gtcccaactt
    13021 tggcacgttt cgcaggtttg atcaatgtct cccacgtatc tccttgtgta ttcgttagaa
    13081 gaaggacttc taaatgcgca ccagtatctg gtttttctcc atataaacga gcaggcagaa
    13141 ctcgtgtatt attcataact agcgcatcac caggctgtaa ctcttcaatg atttcatgga
    13201 aatgtttatc ttccatctct ccagttttcc gatccaaaac aagtaaacga gaatgatcgc
    13261 ggtcttttaa tggtgtttgt gcgattaatt cttccggcaa gtcaaaatca aaatcttctg
    13321 ttgttaacat atcgtcactc actttctatc atgtgcttca tcattctatc atgtttttcg
    13381 ttctgttggc aaaatcagca ctttttcact tctatttttt gttttcctaa ataaaaaaac
    13441 taccctattt gtattttttc attgttttag gcatactagt aatagatagt tcttcattga
    13501 aaatagaaaa agaggtggca ccatgattga atttcaaaat gtgtcaaaaa tttataaagg
    13561 tggaaaagtc gctgtagagg acgtcaatct ttcatttgaa aagggtgagt tcatttgttt
    13621 tatcggtacg agcggaagcg gaaaaacgac gacgatgcgg atgatcaacc gaatgactga
    13681 tccaacacaa gggaaaattt tgattgatgg aaaatccatc caagaaattg atccagtgga
    13741 attgcgacgt cagatcggct atgttatcca aagtattgga ttgatgcctc acatgacgat
    13801 ccgtgaaaat atcactcttg tccaaaaatt gttgaaagtc agtcaagaag aacggaataa
    13861 aacagctgaa aaaatgattg atcttgtgga attgccccgt gagatgttag atcgctaccc
    13921 acatgaatta tctggtggtc agcagcagcg tattggagtc gttcgtgccc ttgcagcgaa
    13981 tcaagatatc atcttgatgg acgagccatt cggtgcgctt gatccaatca ctcgtgattc
    14041 cttgcaagac cttgtcaaag atttacaaga gcgtttggga aaaacgatcg tatttgtaac
    14101 ccatgacatg gatgaagc
//
LOCUS       DACDAF010000071        13852 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.072, whole genome shotgun sequence.
ACCESSION   DACDAF010000071 DACDAF010000000
VERSION     DACDAF010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13852
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.072"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..902)
                     /locus_tag="IVZ69_002020"
     CDS             complement(<1..902)
                     /locus_tag="IVZ69_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HAP8184093.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIAFALKVNPNIGKHMDRFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEGAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFSE"
     regulatory      complement(926..970)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1185..2153
                     /locus_tag="IVZ69_002021"
     CDS             1185..2153
                     /locus_tag="IVZ69_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP8184094.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMD"
     gene            2266..2544
                     /locus_tag="IVZ69_002022"
     CDS             2266..2544
                     /locus_tag="IVZ69_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HAP8184095.1"
                     /translation="MEIKEEKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTFVDPAY
                     RGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            2662..2898
                     /gene="secG"
                     /locus_tag="IVZ69_002023"
     CDS             2662..2898
                     /gene="secG"
                     /locus_tag="IVZ69_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HAP8184096.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3010..3756
                     /locus_tag="IVZ69_002024"
     CDS             3010..3756
                     /locus_tag="IVZ69_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP8184097.1"
                     /translation="MRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKADYTV
                     YAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFAVRA
                     LEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSLAEQ
                     QLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQWYPE
                     SGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            3759..6116
                     /gene="rnr"
                     /locus_tag="IVZ69_002025"
     CDS             3759..6116
                     /gene="rnr"
                     /locus_tag="IVZ69_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HAP8184098.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKARNGKFGKRE
                     GKQAGKRSEKNGKKNKRYSDSKQTFGKKKGKKPFYKDVKKKKKKK"
     gene            6138..6602
                     /gene="smpB"
                     /locus_tag="IVZ69_002026"
     CDS             6138..6602
                     /gene="smpB"
                     /locus_tag="IVZ69_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HAP8184099.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIVRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            6904..7623
                     /gene="atpB"
                     /locus_tag="IVZ69_002027"
     CDS             6904..7623
                     /gene="atpB"
                     /locus_tag="IVZ69_002027"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HAP8184100.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            7676..7891
                     /gene="atpE"
                     /locus_tag="IVZ69_002028"
     CDS             7676..7891
                     /gene="atpE"
                     /locus_tag="IVZ69_002028"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HAP8184101.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            7982..8506
                     /gene="atpF"
                     /locus_tag="IVZ69_002029"
     CDS             7982..8506
                     /gene="atpF"
                     /locus_tag="IVZ69_002029"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HAP8184102.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            8493..9035
                     /locus_tag="IVZ69_002030"
     CDS             8493..9035
                     /locus_tag="IVZ69_002030"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HAP8184103.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9058..10614
                     /locus_tag="IVZ69_002031"
     CDS             9058..10614
                     /locus_tag="IVZ69_002031"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HAP8184104.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            10628..11530
                     /locus_tag="IVZ69_002032"
     CDS             10628..11530
                     /locus_tag="IVZ69_002032"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HAP8184105.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            11553..12959
                     /gene="atpD"
                     /locus_tag="IVZ69_002033"
     CDS             11553..12959
                     /gene="atpD"
                     /locus_tag="IVZ69_002033"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HAP8184106.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            12973..13395
                     /locus_tag="IVZ69_002034"
     CDS             12973..13395
                     /locus_tag="IVZ69_002034"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HAP8184107.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         4575 a         2474 c         3013 g         3790 t
ORIGIN      
        1 ctttcggaaa aaagacgagt atctactttt gtcataattt tactgttagc aggtttctgc
       61 caaaattcat aacgatcaac caatgtttgt ccacgactta ttccctgagt ttccacagcg
      121 gtgaagcttt tgaaaccttc acagatggcc ccctcgatga aataagcaac agctaacgga
      181 tcattgatga cacatcctaa aattctttct tgtttccagt ggaagtcaaa ataaaaacga
      241 gtgatcgctt ttaaatactc tccctcttca ggattcattt gacagcagta ttcgaggata
      301 gtcggtgtca agacgatttc tcttgtcaca tctaacccaa ccatttctat cgtttgtttg
      361 agattctcga atacataaga agctgcttca ggatcacacc agtaattgta ttcagcaact
      421 ggcgaacagt taccatggct tttgtaagtt ccacccatcg agacaaaacg atccatatgt
      481 ttcccaatat ttgggttgac tttcaaagca aaagcgatat tggtcaaagg acccaaagca
      541 atgactgatg tatttgtctt ttctttgaaa taatcagcca aaaaatcaac ggcatggaga
      601 ggttctgcct gttttctcaa gatcatcggg aaatttgttt cccctaaacc atccatacca
      661 tgagtgtctt gtgcactgat gaaaggttgc ttcaaaggtt tttccattcc ttgataaaca
      721 ggaatgtcta aacgatcaca gcgttccagg catttcagca cattctgcgt acctatatct
      781 gcagggacat tcccacaaac tacggtaata gcaactactt cgatatcagg ggatttgaca
      841 gctaatgata aagctaaagt gtcgtcgatc cctggatcgc aatcaataat tacttttcgc
      901 attatttcca atctcctttc tttagagata cttagttttt tattctggga agtttccgaa
      961 ccagtccaag acgagcgtct tgattataat gcacgaaatt agtatactgg cttttattgc
     1021 gaatgtaaat gctctcttac aagtaaatct attgaggaga actttaagta aatgatacaa
     1081 tgaaaaagaa atggaattta cgtgtgccga aaataaagaa tcctatggat cggtacattg
     1141 gataatagat agattatagt ttggcagaaa gcggcgggtg tacaatggtt attttttatt
     1201 tcattcttat tctgataatt atagggatca gttaccattt tctttcttat ttttatgcaa
     1261 agaaattagt aagagcggga gtacagagag gatatgactg gtatgaagac actggtcatc
     1321 gtttgatgga ccctgctgca gtcacgtcag tagaaaaaaa acgacaaaaa ttagaagaag
     1381 agtgtgaaag cttttgggag cagggaacac ccaaaacaat caaaagttat gacgggttga
     1441 aactagctgg tcagatgttc atccatccaa ataagcagaa taaatgggtc atttgcgtac
     1501 atgattaccg aagcacaggg aaaagagaca tgtctcatat aggtaaaaga tatgcagaga
     1561 aaggattcaa cgttcttgta cctgatttac gtgcgcacgg agaaagtgaa ggagaaatca
     1621 tcggaatggg atggctagat cggctagatt taattgcctg gatccaactc atcttagatg
     1681 aacagccgaa tgcgtccatt attttacacg gcggatcaat gggagcttct acgatcatga
     1741 tggcaagtgg tgaaaaactt ccatcagcgg tcaaaggatt tattttagac agcggatatg
     1801 tttctgttta tgcagaattc cgatatatgt taagtaaaat cactgtcttt cctaaaaaaa
     1861 tggtcatgag atatgcgaat cattatgccc agaaatacgc cggttactcc ttaaagcaag
     1921 catcagctac gagacagctt ggcagcaacc atctgccttt attagtcatc catggtgaaa
     1981 gagatcattt tgtccctaca gaagcagcgt acacgattca aaatgctacg gcaggggata
     2041 aagcactgct gcttgttcca gaagcagaac acttggaagc atcgatgaaa gatccgaaaa
     2101 cctattggac agtgattttt tcatttattg aacaaagaat aacgatggat taattttctc
     2161 ttcttttttg taagtaattc gaggataaat aattgtttat agatctggag actgctaaaa
     2221 taaggtagga ataaaaaaat atcagttatt tgaggagtgc ggcatatgga aatcaaagaa
     2281 gaaaaaaatc gtcttgcttt attcaatgat gagcaacaag agattggaga aatgacatgg
     2341 tcagatgcgg gcccagacat catgatcatt gaccatacat ttgtagatcc agcatatcgt
     2401 ggtcaaaagt tagctgaaaa gctagtgtat actggagtag aattagcaag acgagacggg
     2461 aaaaagatca ttcctttatg cccttatgca aaaaaagagt ttgaaaagaa accagaatat
     2521 caagacgtct tacgtcagtc ataagaataa cagctgaaag ttttgaactt tcagctgtta
     2581 ttccatttat atagagttgt cacggacttt tatctatgat aaagttaaag agacgatatc
     2641 ttttgggaag gaggctgcga tatgtataat ttaattttgg gaatcgtgat cgttttatcg
     2701 attgttatgg tcattgcgat tatgatgcag ccaagcaagc aaaatagtgc agcgagtgca
     2761 tttaccggcg gtgcggatca actattcggc aaacaaaaag ctcgcggctt tgaagctgtc
     2821 atgcagcgat caactgcagt tatgggagct atctggatga tcttattatt tgtcctagca
     2881 tatttatctt cgaagtagtt gaataagcct ctcgcaaaac ggcgggcggc tttttttatt
     2941 gcaaagagaa cgcttaagaa gaagttatga aagaaactat ggtaaaatga ggcgaaagag
     3001 gtgagacgag tgagacaatt accaaaaccc ctttatgcaa aacatggaaa gcgagcggtt
     3061 ttgctgcttc acgcttactc aggaagtcca aacgatgttc gaatgctcgc acgatttttg
     3121 gaaaaagcag attatacagt ttatgcgccg ctttttaaag gacacggaac aatggagcca
     3181 tatgatatct tgcaagaaaa agcagaaagc tggtgggcag acactaaaaa agccatccat
     3241 tttttacagt ctgagcagtt ttctgatatt gccgtattag gattatcaat gggcggcatc
     3301 tttgctgtac gagcactaga agaagaatca gtgattggcg gcggtttttt ctgttcgcct
     3361 ttgtctcctg taaaaacaaa cgtgcctgaa aactttgaaa aatacgtacg tcaagtgctg
     3421 aagacagcag gtaaatcaga gaaagaaatc aatgaaaaag cagttgctta ccgctcgtta
     3481 gctgaacaac aattaatgga tatacaagat caggcagcaa tcgtagaaag taggttgtca
     3541 gatatccaac agccgatatt tttagctcaa gctgggaaag atgaaatgat cgaccctaat
     3601 ggcgtatttg aaactgcacg caagttgagc cgtcagcgag tgacacttca atggtatcct
     3661 gaaagtggtc atgtgattac agttggtaca gcaagacgcg aattagaaaa agacgtcttg
     3721 gaatttttag aaaaattacc ttggaatgag gaataaatat gacaaaagaa acgataaaag
     3781 agaaaattct ctttttcatg gaaagcagtc gcaaacgcag tttttctatg gaagaaatcg
     3841 ctgaaggttt agggttccaa aaaagcgatg attttaaatt actagtacaa acgattgctc
     3901 aaatggaaag agaacagagt atagttttca ataaaaaagg aaaagtgaaa cttcctttaa
     3961 aaccaatctt gatcgaagga acatttcgag caaatgaacg aggatttgga tttgtaacga
     4021 ttgatcccga agaagatgac atctatatcc caaaagaagc gactggtttt gcaatggatg
     4081 gagacaccgt agcaatcgat atcatgaagc gagcaaatac agatatggat cgcggagcag
     4141 aggggaaagt agtcgagatt cgagaccggg cgactactca gttagcaggg gaattcgttg
     4201 cttattcaga agaagaaata caagaaacag atctttacgg cgttgttatc ccgaaagata
     4261 gaaagctcaa ccaatttaaa gtatatgcag cagcagaggg agttcgtcca gttgacggaa
     4321 gtattgtgct gatcgaactg acccattacc ctgaaaaagg gtatgcgact agtttagaag
     4381 ggataatcaa gcaagtgatt ggtcataaga atgaccctgg catggatatc ctctcaattg
     4441 tcgtggctaa tggtatccct acgaaatttc ctgatgatgt attgtctgaa gcagatgaag
     4501 ttccagatca aatcagcgaa aaggatataa ctggacgtag agatttaaga aatcagctca
     4561 ttgttacgat tgatggagaa gatgcaaaag atctagatga tgcagttacg gttaaaaaat
     4621 tagataacgg taattatttt cttggagtac acattgcaga tgtttcttac tatgtgacac
     4681 aaggcagtca attggacaga gaagcatatg aaagagggac aagtgtatat ttgactgatc
     4741 gagtgattcc gatgatcccg caacgtttat cgaatggtat ctgttcactg aatccccatg
     4801 ttccaaggct gaccatgagt tgcgaaatgg agattgatcc aaatggacaa gtagtctctc
     4861 atgatatttt cccaagtgtg atccaaacaa cagaacggat gacctacaca gctgtcaatc
     4921 aaatcttaga agatcaagac gaagaaacga tgcaacgcta tgctcagctc gtacctatgt
     4981 tccaagaaat gggtgaattg catcgaatcc ttgaaacgat gcgaatcaaa cgtggcgcga
     5041 tttcttttga ggatcgcgaa gcgaaaatcc ttgttgatgc tgaaggacac ccaaatgaca
     5101 tccagctaag aagcagagga attggtgaac gcttgatcga atctttcatg cttgcggcca
     5161 atgaaacggt agctgaacat tataataaat taaatctgcc gtttatttac cgaatccatg
     5221 aacagccaaa agaagaaaaa atgcagcgct tctttgattt tgcttcagct ttgggcattc
     5281 tggtccgagg aacgaaagga acgatcacac caaaagattt acagcatgtg atcgaaggag
     5341 tagaagacaa accagaagct gcagttatca atactatgtt gctaagaagc atgcaacaag
     5401 cacgctattc agaagacaat tttgggcatt atggcttagc ggcagattac tacacacact
     5461 ttacatctcc tattcgacgc tatcccgatc taatcgtcca tcgtctgatc cgttcttaca
     5521 gtgaagataa aagtgaaagc aatcaaagtt cgtgggctgc ggaacttcct gaaattgcag
     5581 atcatagttc taagatggaa cgtcgtgcag tagaaacaga acgtgaagta gattccatga
     5641 agaaagcaga attcatgatg gacaaagtgg gagaagaatt cgatgggatc atcagctctg
     5701 ttgtgaaatt cggcctgttt atcgaactgc cgaatacagt agaaggattg atccatatca
     5761 atgaattgaa acaggactac ttccattttg ttgaaaatca tttagctctt gtaggtgaaa
     5821 gaactggtct gacttttaaa atcggacaaa aagtgcgcgt aaaagtagtc aaagctgatc
     5881 cagatgaacg agcagtggat tttgaactcg tttccgcaga agaggtcact gcgttggaac
     5941 gtccaaaagc acgcaatgga aaatttggaa aacgagaagg aaaacaagca ggcaaacgct
     6001 cagaaaaaaa tggcaagaag aacaaacgat atagtgatag taagcaaacg ttcggtaaga
     6061 aaaaagggaa aaagccattt tacaaagatg tcaaaaagaa gaaaaagaaa aaataaaatg
     6121 agttggagga aacagctatg ccaaaaggcg agggaaaact aattgcacaa aacaagaaag
     6181 ctcgccatga ttattcgatc atcgacacga tggaagcagg gatggtcttg caaggaacgg
     6241 agatcaagtc gatacgaaac agccggatca atctgaaaga tggatttatt cgcgtccgca
     6301 acggggaagc tttcttgcat aatgttcata tcagtcctta tgaacaagga aatattttta
     6361 atcatgatcc gttgcgcacg agaaagttat tattacacaa gaaacaaatc gttcgtcttg
     6421 aaaacgaatt gaaaaacact ggaatcactg ttgttccttt aaaagtctat attcgtaacg
     6481 gctatgccaa ggtattgatt ggtctggcaa aagggaaaaa atcgtatgat aaacgggaag
     6541 atttgaaacg aaaagatatc gatcgacaaa ttgatcgaac attaaaaaat ttctctagat
     6601 aatttcatta tcctttttcg catattcggt gcttttgctt ttacttaatg ataaaatttg
     6661 ttagcattta atctgataaa acatgattat cacaggtttt ttcttagatc aggagcaccg
     6721 tgcatgggga aaaattcgct tcgtttttga ctgaaataaa aaagtgtcta attttcatga
     6781 aaatgttttg aattttctgt ttcatggtgg tatgataccg tgtggttaga aaccgattgg
     6841 aaaaaaccag atacgcacat gaattgattt tatgtgaatt tcggggaaaa gaggtgaaat
     6901 ggattggatg aacgctcgct aacgtttcac attggaccaa tttggtttga tggtacagtt
     6961 tgtataatgg tgttactgac ctgtttgatt gttttcttct tagcttactt ttttacaaga
     7021 aatcttaagt tgaaaccaac aggcaaacaa aatgcgatag aatgggtcat tgattttagt
     7081 cgaggaatcg taacagataa tctgcctaga aaagaattga gcaatttcca tttgttggca
     7141 tttacattgt ttttatttgt ttttgttgca aacaacatag gtttagtaac aaaaatcgtc
     7201 ttacctaacg aaacaacact ttggaaaagc ccgacagcag acccgtttgt tactttaact
     7261 ttggcattta taatgatctt acttactcac ttattcgggg tgaaaaagtt aggcttcaaa
     7321 ggatatttcg taaattcgtt cttgaaaccc tatagtttta tgtttccgat gaaactgatt
     7381 gaagaattta caaatttatt aacacttgct ttacgtcttt atgggaatat ttatgcgggg
     7441 gaagttttgc taaccttgat tgcaaaaatg atgacaagct taggctggtt ctcattacca
     7501 ttagcaattc cattagagat ggtctggatc gcgttctcct tgtttattgg gagcatccaa
     7561 gcatttgtct ttgtcacttt gtcaatggtt tatatgagcc ataagattga agtagaagaa
     7621 taatactcgg ttaaaaaaca aactactatt tatctatttt aggaggaaaa caattatgaa
     7681 ttatatcgca gcagcaatcg caatcatggg agcagcaatc ggagccggtt atggtaacgg
     7741 tcaagttatc tctaaaacaa tcgaatcaat ggctcgccaa cctgaaatgt ctggtcaatt
     7801 ccgtacaaca atgtttatcg gggtagctct agttgaagct gttcctatct taggggtagt
     7861 tatcgccttg attctagttt ttgccgttta attgaatcag tattaaggca gaaacaacat
     7921 cgtttgttac tgctttttta catggaaact agaaatactc caaagaaagg aaggctcgcc
     7981 tatgctgaat caattggcaa ttgcagaagt tggcaatgcg atgttaggta atatcatcgt
     8041 tgtcagcggc tcatttttga tactactggc tctcttgaag cactttgctt ggggaccaat
     8101 cagcgatatt ttgaaaaaac gtgaagacaa gatcgccaat gatttagatt ctgcagaaca
     8161 atctcgcatc aactcagcga aaatggaaca agaacgcgaa caacaattgt tagcctctcg
     8221 ttctgatgca gctgatatca tcaaaaatgc gaaagaaagt ggagaattaa gccgccaaaa
     8281 tattttgaag gatgctcaag aagaagcagc tcgtctaaaa agcaaagccc aagctgatat
     8341 cactgtagaa cgtgattcag cgctgaactc tgtaaaagac gacgttgcag aactctctct
     8401 tcaaatcgcg gaaaaaatct tgaacaaaga attatctcca gaaatgcatg aatcattaat
     8461 caatcaatac attgaaggtc taggttcttc aaatgaaact agataaatat acagtaggaa
     8521 gacgttacgg gaaagcttta tttgaactgg cgatcgattc aaatcaagca gaagaaatct
     8581 atcaagatct cgtaagttta cgtcaaatct atgaacaagt acctggatta gggaatatgt
     8641 taagtgatgt tcgtctagaa cctcatgaaa aacgagaaat catggacaag cttgtcagcg
     8701 gttatgatgg gatcgttaaa aactttttag aagttgttta tgagtataac cgaatggatg
     8761 accttttgtt catgatcgaa gaatatgaac gtcgatatga tgaacatcaa gggttactat
     8821 tgggaagtgt cacaacagca gtcccacttt cagacgaaca acgaatacaa ttagaaaaga
     8881 atgttgcaaa aacaatggac tatcaatcag ttgaattaaa acaaatcgtt gattcttcta
     8941 ttattggtgg cgcgattgtt gaagccaacc atcgagtaat cgacggaagc attcgcacgc
     9001 aattagaaaa aatgcgtaat caattaaaca gatagtacaa agaggtaggt gaatcgaatg
     9061 gccatcaaag cagaagaaat tagtgccttg attaaagaac aaattgaaaa ttatcaaaac
     9121 gtgctttcag tcgaagaaat cggtaccgta acttatgtag gtgacgggat cgctcgtgca
     9181 catggtttag aaaacgcgat gagtggtgag ttgcttgaat tttcaaacgg ctcatacgga
     9241 atggcgcaaa acttagagtc aaatgatgta ggtatcatta tccttggcga tttcgagtcc
     9301 attcgtgaag gagataaagt aaaacgaaca ggtaagatca tggaagttcc agttggagag
     9361 gccttgatcg gtcgggtagt caatccgcta ggtcaaccaa tcgacggact aggtgaaatc
     9421 gttactgaca aagctcgtcc agtagaagcg atggcaccag gtgttatgca acgtaaatct
     9481 gttaacgaac caatgcaaac agggctaaaa gcgatcgacg cccttgtgcc aatcggacgc
     9541 ggacaacgtg aattagtcat cggtgaccgt aaaacaggga aaacttctat tgcgatcgat
     9601 acgatcatca accaaaaagg tcaagatatg atctgtatct atgtagcaat cggacaaaaa
     9661 gattctacag ttcgtacaca agttgaaaca ttgaaaaaat atggcgcaat ggattacaca
     9721 atcgttgtga atgccggtgc gtctcaacca gcaccattgc tttatatcgc accatatgct
     9781 ggtactgcaa tgggtgaaga attcatgtac aacggtaaac atgtattgat catttttgat
     9841 gatctttcaa aacaagctgt tgcttatcgt gaactttcct tgctgcttcg ccgtccacca
     9901 ggtcgtgaag cttatccagg ggatgttttc tacttacact cacgcttatt ggaacgtgca
     9961 gcaaaattaa gtgatgattt aggtggcggt tcaatgactg ccttaccatt tgttgaaaca
    10021 caagctggag atatctctgc ttatatccca acaaacgtta tttcgatcac tgatggacaa
    10081 atcttcttag aaagcgactt gttctacgca ggtactcgtc cagcggttga tgccggacta
    10141 tctgtatctc gtgtaggggg ttctgcgcaa atcaaagcaa tgaaaaaagt tgctgggact
    10201 ttacgtctag acttagcaag ttaccgtgaa ttagaagcat ttacacaatt cggttctgac
    10261 ttggatgcag caacacaagc aaaactaaat cgtggacgcc gtacagtaga aatcttgaaa
    10321 caaaaattgc atgcaccgct agctgttgaa aaacaagtag tgattttgta tgctttgaca
    10381 catggattct tagatagtat ccctgtagac agtattttag acttcgaaca tgaattattc
    10441 gaatatctgg ataccaatca ttcagatatc tttgaaacaa tccgtacaac aaaagatctt
    10501 ccagaagaag aagcgttgaa cagtgcgatt caggaatata aagacatgtt cttagctaca
    10561 aaaggaaata attcctctac agaagataaa ttgaaatcca ttcaaaatgc atagtgaggt
    10621 gagatgaatg ggtgcttcat taaatgaaat caagacacgt atcgcttcaa cgaaaaaaac
    10681 gagccaaatc acgcgggcaa tgcagatggt gtctgcttct aagttgacaa aatctgaagc
    10741 ttcttcacag aagtttcagg tttatgcaac aaaagtaaga gaaatcgtta cgcatttgac
    10801 tgctactcag ttaaatgata ttgcctcaga aaatcctaga ggggatatca attacaacag
    10861 catgttgctc agccgtcctg ttaagaaaac gggttatatc gtcatcactg cagatggcgg
    10921 tttagtcggt ggatataaca gctcgatatt gaaacaaacg atgtctattt tagaagaaga
    10981 ccaccaatca cccgatgatt acgtgatgat cgcaattggc ggaactggtg cagacttctt
    11041 taaagcacgc ggtatcaatc tagcatatga gctgcgcaat ctatctgatc agccaagctt
    11101 tgatgaagtc cgcaaaatcg taaatatggc aacaactatg taccaaaacg aagtattcga
    11161 tgaattatac gtatgttata accatcatat caattcgcta actagtcagt ttcgtgtaga
    11221 aaaaatgctg ccaatctcag acttagatcc agaagaagca actactttcg aacaagaata
    11281 tatttttgaa ccttcaaaag aagaaatctt gtctcagtta ttgcctcagt atgctgaaag
    11341 tttgatctac ggtgcgatcg ttgacgccaa aacagcagaa catgctgctg gtatgacagc
    11401 aatgaaaaca gcaactgata atgctgctaa tatcattgat gagctgacgg tttcttacaa
    11461 ccgtgcaaga caaggggcta ttacccaaga aattaccgaa attgttgccg gagcttcggc
    11521 actagaatag tattgagatt ggaggaaaaa agatgagttc aggcaagatt gttcaagtaa
    11581 tcggtcccgt tgtcgacgtg gaattttctt tagaccaatc cttaccagat atcaacaacg
    11641 cattagttgt ttataaaaat gacgaaaata aatcaaaagt tgttcttgaa gcagcgttag
    11701 aattagggga cggagtgatc cggaccattg cgatggaatc aacagatggt ttacaaagag
    11761 gaatggaagt cattgataca ggcaaagcaa tctctgttcc tgtaggtaaa gaaacattag
    11821 gtcgcgtatt caacgtacta ggagatacga tcgatttaga aacacctttc ccagaagatg
    11881 cggaaagaag cgaaattcat aaaaaagcac cagcctttga cgaattaagt acaagtacag
    11941 aaattttgga aacagggatc aaagttatcg atttgcttgc cccatattta aaaggtggga
    12001 aagtcggact attcggtggt gccggtgttg gtaaaaccgt actgatccaa gaactgatcc
    12061 ataatatcgc ccaagaacat ggtggtattt ctgtatttac cggtgtaggt gaacgtactc
    12121 gtgaaggtaa tgacttgtat tatgaaatga aagattcagg agttatcgaa aaaacagcca
    12181 tggtgttcgg acaaatgaac gaaccaccag gtgcacgtat gcgtgttgct ttgactggtt
    12241 tgacgattgc ggaatatttc cgtgatgtag aaggtcaaga tgtactgttg tttatcgaca
    12301 acattttccg tttcactcaa gctggatctg aagtatcagc cttgttagga cggatgcctt
    12361 ctgcggttgg ttatcaacca acattggcaa cagaaatggg tcaattgcaa gaacgtatca
    12421 catctacgaa aaaaggttcg atcacatcga tccaagcaat ctatgtgcca gccgatgact
    12481 acactgaccc ggcgccggca acagcattcg cccatttgga tgcgacaacc aacttggaac
    12541 gtaaattaac agaacaaggg atttatccag cggtagatcc attggcttct tcttcaagtg
    12601 ctttagcacc tgaaatcgtg ggagaagaac attataaagt agcaacagaa gtccaacacg
    12661 tattgcaacg atatcgtgaa ttacaagata tcattgctat cttaggtatg gatgaattat
    12721 ccgatcaaga aaaagtgtta gtttctcgtg cccgcagagt ccaattcttc ttgtcacaaa
    12781 actttaacgt ggctgaacaa tttactggtc ttccaggttc atatgtccct gtagaagaaa
    12841 cagtgaaagg attccgcgaa atcttggaag gcaaatacga tgatcttcct gaagaagctt
    12901 tccgaagtgt tggccgaatc gaagacgtcg tagaaaaagc gaaaacacta ggctactaga
    12961 aaggggtgcc ccatggatca atatttaaca gtaaatgtgg taactcctgc cggtttggtc
    13021 tatgatcacc atgcagctat cgtcgttgca cgtacgacag ctggtgagct tgggattttg
    13081 cctaaacatg caccaatcat cgttccattg acgattgatg aagttcgtgt aaaacgaaca
    13141 gattcagata cccacgtcga ttggatcgct gttaatggcg gaatcatgga agttcgtgat
    13201 aatgttgttt caatcgttgc tgatagtgcg gaacgtgaac gtgatatcga tgtatctcgt
    13261 gcggaacgtg caaaacaacg cgcagaacgc caaatcgaag aagcaaaagc aaaacaagat
    13321 acgaacgaat tgaaacgggc aactgttgcg ttgcaccgag caatcaatcg tatcaaagta
    13381 tctaagcact cataaaatga gatgcggatg tttatccgtg tttaagaaca gtaaaaagag
    13441 gttatgacag aagtggtcag cttcaagaca taagaaggaa tttacgaaaa ttgcttctca
    13501 aatttttgtg aaatctcagc ttatttttcg aagaagctac ttctggaaca ccgtatatcg
    13561 gaggttgtga aatcagcgtt ttgtcctgag tattagagaa acaaatggaa aatagttcct
    13621 catattttgc cgttttttga gctaataccg agggtcagat gattgaacac cgtttatttg
    13681 gaataaggga ctgcgacaag acttttgtgg ctctttgtca ataaggactg atgagttgtg
    13741 caaaatcaaa tctgagtcag aatgaaccac attctggctc agattttttg ttatcttaca
    13801 ttgattaatt gattgatcaa aaagattcta attctcatgt tctcaaatga tt
//
LOCUS       DACDAF010000072        13397 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.073, whole genome shotgun sequence.
ACCESSION   DACDAF010000072 DACDAF010000000
VERSION     DACDAF010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.073"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            194..493
                     /locus_tag="IVZ69_002035"
     CDS             194..493
                     /locus_tag="IVZ69_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184108.1"
                     /translation="MDYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKP
                     VRTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(590..1024)
                     /locus_tag="IVZ69_002036"
     CDS             complement(590..1024)
                     /locus_tag="IVZ69_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8184109.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1256..1966)
                     /locus_tag="IVZ69_002037"
     CDS             complement(1256..1966)
                     /locus_tag="IVZ69_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HAP8184110.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1956..2816)
                     /locus_tag="IVZ69_002038"
     CDS             complement(1956..2816)
                     /locus_tag="IVZ69_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HAP8184111.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2821..3459)
                     /locus_tag="IVZ69_002039"
     CDS             complement(2821..3459)
                     /locus_tag="IVZ69_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HAP8184112.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3474..3773)
                     /locus_tag="IVZ69_002040"
     CDS             complement(3474..3773)
                     /locus_tag="IVZ69_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8184113.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKEVTVIGIKNVMSAKEISEKFAETKWYQKNK"
     gene            complement(3816..5300)
                     /locus_tag="IVZ69_002041"
     CDS             complement(3816..5300)
                     /locus_tag="IVZ69_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HAP8184114.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQVLIFMGLILGCYWAVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPEGYFLIVEDYDTYAEKQRV"
     gene            complement(5320..5781)
                     /locus_tag="IVZ69_002042"
     CDS             complement(5320..5781)
                     /locus_tag="IVZ69_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HAP8184115.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGEDEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5799..6866)
                     /gene="ulaG"
                     /locus_tag="IVZ69_002043"
     CDS             complement(5799..6866)
                     /gene="ulaG"
                     /locus_tag="IVZ69_002043"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HAP8184116.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADSKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7084..7854
                     /locus_tag="IVZ69_002044"
     CDS             7084..7854
                     /locus_tag="IVZ69_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP8184117.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8127..8954)
                     /locus_tag="IVZ69_002045"
     CDS             complement(8127..8954)
                     /locus_tag="IVZ69_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184118.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9521..10756
                     /locus_tag="IVZ69_002046"
     CDS             9521..10756
                     /locus_tag="IVZ69_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HAP8184119.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(11755..12015)
                     /locus_tag="IVZ69_002047"
     CDS             complement(11755..12015)
                     /locus_tag="IVZ69_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HAP8184120.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12042..13343)
                     /locus_tag="IVZ69_002048"
     CDS             complement(12042..13343)
                     /locus_tag="IVZ69_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8184121.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEKAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNATLLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPMIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
BASE COUNT         4260 a         2774 c         2112 g         4251 t
ORIGIN      
        1 agacgcagtg ttgacaattg aaaaaaaata aatgtttgta taccatatga ttatttcaat
       61 atgtatcctg gaattggaga tctcgtagag ctatatcaag atgaatcaaa tatacttgtc
      121 attcatcatg aaatatagag acttataaaa ttgtttattt ttataatgta tcagtataga
      181 aaggaaataa aacatggatt atactgttga atttgacagt gaactactta agcaatttcc
      241 acaagaagaa catttcatgt ataaagaagc aatttcccac aaagtgacag agtatttgga
      301 gcataatttt tttcgtataa agccagtgcg tactcgttcg gcaaaaggaa tatacgagat
      361 gaaagtcaaa attaataaaa aaaattatcg catagcattt gctttaaaaa aaaatcatgt
      421 gttcattttt tatattagtt cgaatttgca aaaaattgta tttgataaag aggtgagtaa
      481 aaaaataaaa tagctgagca ttggaggata gattgagtga tactaagtct atcctcttgt
      541 ttttctaaag aactaagcta gaattttttc ttttgtacgt tattatatgt tatttgtcat
      601 taccaaaaag cacctttttt cttctagtat ctatgacata agaaatacca cccatttcct
      661 ttacttgaac aaatcctact gattcataaa atttttttgt tttctcagta tcatctgtca
      721 ataattcgat ttggactggt ccataactag tgatcttctc caaagcttca ttcaaaagca
      781 ctttgcctat tccttggcgc tgatacctcg gatgaatgag gatatcttga ataaatgcga
      841 tcgtcgcaaa atcagtgatc caacgaacga ttccgataat cttcccttcc ccattacgct
      901 ttatcagaga ttcagattgt tcaaatgctc tagctaacct tgcagtgtct tttgtgtaat
      961 tcgtccaacc aacgctctta tataattcag aaatctcatc gatcataagg gaatcaatat
     1021 tcattttttt cttcctttct tatacaattc tccctctaat aatacagttc tttgactatt
     1081 taatctatca catataactc tcctgtaaag attctctcga ttccttaaaa tctctctttc
     1141 cttttagaat gcatcctttt tgataaataa aaaggttgtg ataaattttc ttcacaacct
     1201 ctgtttctct ctatcaagtg ttatctttta attttctacc cttaccctag catctctatt
     1261 gcccgtagta tgcatacttt ccatgtttgc gaaaataatg tttatctagt aaatattgcg
     1321 ggatttcaca tatattgggg ttgatcagct cgttttcttt ggccatcaga caaatttcat
     1381 ctaagatcaa actgttttct actgctttca taggtgaatc cccccatgtg aacggtccat
     1441 gtccatagac aagtactcca gggacttcgt ttggatctaa ttttctttcc ttaaacgtct
     1501 cgacaatcac attccctgta tgaacttcgt aagcttctct tacttcttct ttcgttaatt
     1561 ggcgtgtaca aggaacctta ccataaaaag catcagcatg agtcgtgcca taagctggca
     1621 aatcgcgtcc tgcttgcgcc cacatgacgg agtgcgtgga atgagtatga gtaatagcag
     1681 ttatatcttc aaaagtttga tacaaaacaa catgtgtggg gagatctgaa gatggtttta
     1741 agctatcttc ttctattata tttcccgaca aatctgttac caccatttga tctgcttgca
     1801 tgcattcata tctgacaccg cttggcttaa tgacgatgac tcctagctca cggtccactt
     1861 cactcacatt gccccaagtc aatttgacta atccgtatcg cggcaatgcc agatttgctt
     1921 caaggacacg ttgcttcatt gctgcaattt tttcttcaca agacatcata gccagcctcc
     1981 ttcaatttag aacttaagta gtcttttgcc tgctggattt ctcttcgaaa gtcttggctt
     2041 ttttcactcc acatttcaat cagaaatgtt ccatcataat ctagacgttt caaatgtctt
     2101 aataatccaa gaaaatcaac acaaccgcta ccaaaaggaa catcacgaaa ctggcctgaa
     2161 tattcttttg ttacagggta agtatctttt aagtggatag cagtgatata atcgatccct
     2221 ttctcaagtt ctcgagccgg attattttcc ggccatgcgg acaaattgcc taggtctgga
     2281 tatacttgta gaaaagggga atgaatctgt tctttgattt ctaaaaattt tgaaatggag
     2341 ttcataaatg gatcatccat gatttccacg gaaagaatga tgccatattt agaagcttcc
     2401 tttacgcttt cttttattcc ttcgataaag tcttctctgg aattcattga tttctcttca
     2461 taataaacat cgtatccagc tatttggatt actttgacgc ttagattatg cgccaaatgg
     2521 attgcttttt tcattagttg tttcgctgct tttttctttt ctggatcagc agaaccaaac
     2581 ggaaatcgcc gatgcgcact taaacaaatc gaatggatac gtacaccgga gctgaacatc
     2641 tcttctctca gctcagctat cttttcttca gaccaatcta atcgtgctaa ccgctcatcc
     2701 gtctcatcaa tcgacatctc gataaaatcg aagtccattt cttttacaag ggaaaaacgt
     2761 tctttccatg aaatatcttt gggtaatgct ttttcataaa tcccaatttg agccatttcc
     2821 ttacccccag atacgaatga tctcatcttt gaagttttgt gcggccttca tcggatcatt
     2881 tgctgctgta ataccacgac cagtgataaa ggtatacaca tcgatccctt caaataagtg
     2941 taatgtgtgt ggatttaatc caccagttac agaaacatta aagcctagtt caatcagttt
     3001 tttgatcttc gataaatctt tttcacccca agtttcacca gataacagcg catcacggct
     3061 ttgatggtag attacctgcc ggataccgat gttatgccaa tccatggctt gttcaaaagt
     3121 ccaattgccg tagagttcta cttgcaattc acctatttct ttttgtgctg cctccatagt
     3181 tggaatcgtt gcacaacaaa tgactgtcat ccagtctgct cctgcttttg caacattact
     3241 cgccactgtt cctccagcgt ctgcacattt cgtatcagcg actagttttt tatctgggaa
     3301 catactgcga atacagcgaa tcgctttttg tccttcctgt aagcaaagaa ttgtgcccac
     3361 ttcaataata tctactacat caccaacttt cataacatct cctaatgcat gttctaagtc
     3421 attgtgatct aacgcaattt gcaaattcgg cctgctcatc ttagttcctt cctttacttg
     3481 tttttttggt accactttgt ttcagcaaat ttttcactga tttctttggc tgacatcaca
     3541 tttttgatac cgataactgt aacttctttt ttctctgcct gagtaaacat attcaaaaaa
     3601 ttgactggcg taaaaactac atcgtattgg ccagctgaac tttttccctc tgaaatggca
     3661 caatgatgga ttttggtaat tggtacgttt agttctttca ttgctttttc cacacttctc
     3721 atcatcatca agcttgttcc tgatccattt gcacacgata ctaaaattct catcttaatc
     3781 cctccattat gagtgttgtc taatcagatt ttcttttata ctctctgctt ttctgcatat
     3841 gtgtcatagt cttctacaat caaaaaataa ccctcaggat ttttccgata ttgtaactgc
     3901 ggaatagcca ataaaccaat gacaactacg gcaattccag cataacctag gactttcatg
     3961 attactgtaa acaatggcca agctgttgcc cagtcgaaca tcccgatata accaccatat
     4021 gttgacatcc caatccatgt agcgaataat gctgaaccgc ctacttgtat gattcctgaa
     4081 agaaacggga acaggcaagc ggctttgaat ccacctcggt tattggcata aactgctata
     4141 acggcattat caaagaacaa cggaatgaaa ccggctatga cgatcgttgg tgatttcaat
     4201 aaaatcagta aaccaatcat caaaaactgt cccaaagcac caaacaagaa cccaatcgtt
     4261 accgcatttg gcgaaccaaa gccaaaagta gcagctacgt caattcctgg aacagctcct
     4321 ggtaaaattg tgtttgagat tccttggaaa gattgagtta gttcatcgac gaatgtccga
     4381 acacctaatt gcaagatcgc cagatatacc gcaaaattta aagaagtcgt cataatgtag
     4441 aataagaaac tctgtccttc ttgcatgaat tgcgcttgaa tcaaataatc tttgcctagt
     4501 acaatcagaa tgatcccaaa gaaaaatagc atgagtaacg aagtagcaac catattctca
     4561 ttgaaaatcg acaagaatcc tggtaatttg atatcttcga tttttttgtc ttgcttgatt
     4621 gatctatttt tcttttcatc ccgctttttc atccactcag ctaattttgc aaatataaag
     4681 attccgaaca tttgctgatg tgccactgca aatccggcac cttctgtcaa ttcctgcgtg
     4741 attcctactg ttaagttaga agctactgcc caataacaac ctaaaatcag tcccataaaa
     4801 atcaatactt gtatcctacc tagatcagga aagcaaaaca gtaaaatcca aaaagcggta
     4861 gctgcttgtt gaacctgaac gtttccggta gtgaaaacgg aacgcagttt cgtatatttc
     4921 tgaaaacgga ctaataagat atttaaaaca aatgcaatca gtaataaaat catcacatct
     4981 ccaaaggtac ggccaaatgt ctccattaat ccagcatcca cagcattttg tccaaaataa
     5041 ggatctgtaa ccatggcatc caaattgaac cgttccttta gtccaaccaa aatcggccga
     5101 aaattattga ccaaaccacc agagccaaca gtcaaaataa agtaaccgac cgttgccttt
     5161 aagaatccag cgatgcattc atgaagcggg cgtttcagca aaatatagcc taataacacg
     5221 ataaaaccaa tcaggtatgc tggctgcgtc aagatatttg ttgcaaaata cgtccaaatg
     5281 cttaacaaaa attcccccat cttttttctc ctctatcaat taattatatt ctgccatcac
     5341 aacttggtaa tcatcgatgg agttcgtaga gatgagacgc tcaaccaatc catctgtcat
     5401 taataattcg gataattttt ggatattttc tagatgttct tctggatctt ttgctgcaag
     5461 tgtaaaaaac aaactagccg ttttctcctc atcctcccct tcactttcaa aacggattgg
     5521 ctgtttcaac ttggtaaatg aaatagctgt tccaaaaaca ccatcacttt tttctgaaga
     5581 atgcggcatt gctacttgag gtgcgatcac aatataagga ccgtattttt ctacacaatg
     5641 gatgatctcc tccacatacg tttcatcaat aatttcctta tcgatcaata caagacagct
     5701 ttcggcgata gcttcacgcc aatccgtgat ttctttatct gggtaatgaa tcaattgatg
     5761 gtcaaaaaag tatttcagca agaaactccc cttctttctt ataaaaacga cggaaacggt
     5821 gtatcatttt caatcgagaa gacatcttca aatcctcgat aaaaattaaa ctcaagatca
     5881 tctttgtttg tcggatagat gaatttcccg cctacttgcc agatataagg tttaaatcca
     5941 tacttcaggc gatccttttt gaatttccaa atttcagtga tctcttttga atcagccata
     6001 aaattagacc aaatatcgta gtggacagga atcactactt ttgcattcaa tgactccgcc
     6061 atgcgcagca tatcaacaga agtaactttg tctgttatcc ctcgtgggtt ttcaccatag
     6121 gcccctaaac agacatcgat tttgtgttca ttaccatgtt tggcaaataa attggagtaa
     6181 tgtgaatctc ctgcatgata aagattccct cctgatgttt cgaataaata gtttactgca
     6241 atttgatcca tctcctgagg catttttcct tttaatacct cttctggatc ttcacaagtg
     6301 accaacgctg tccgatcaaa cgcttctaaa gctactacat tgatgtcttt gattttgact
     6361 gcatcacctg gctttactgt aatcgttttt tcttcaggaa ttccccattt ttgccacgtg
     6421 cgaaccactt cttttggccc aatgaatgtt gcttcaggac aattttgatg aactgctgcg
     6481 gctgtatgga tatctagatg atcggaatgg atatgtgtaa cgattaaagc gtctacattt
     6541 tttatcgcaa aaggatcgat tacgaaaggc tgagtacgta aattaggctg catattttga
     6601 acgccactca tacgcatcat ctgatggcct tttttcatca tgccattccc atgactacgt
     6661 tttcccgtcc cacaccatag atcacataaa atattcgttc cttcatgact tttcagccaa
     6721 attcccgtac agcccagcca ccacatagca aaagttccag gatccactac ttctgtttcg
     6781 atttcttcat tcaagtatgt gccccactca ggaaatgttt ctactaacca cttttctttt
     6841 gttacttcat tgacagtttt actcatttgc ttgctccccc catatcgttg ttccaactta
     6901 caagtaaata ttaatgtgta tcagcatcca tggaaaccct tttatatgac cgtttgtttt
     6961 ttatatgatt ttctttcagt aatcaatgat tgtttcagta taataaagac agatatgaat
     7021 gtttaaatga acaactagtc aaataaatcc atggatcaag atgtccctca ggaggcaaaa
     7081 gtcatgaaaa actcacttgt caatattgaa aaacgtcaaa aagaaatttt ggaactgctt
     7141 cagcagactg aacaactatc aactttcgaa ttagctgaat cccttgatgt atctattagt
     7201 acgatacgaa gagatttaaa tttattagaa gaaaaaaacg agatcatacg caattacggt
     7261 tattgttctt ataattacaa aaaccagact gattttgatc aatctggtcc tgaaaggatt
     7321 aaacaagcga ttgccagaga agctagtaaa tacattaacg attatgatac gctgtttatc
     7381 aattctagct cgactgcgtt gaaaacactg gattttcttc aatctaacca tttgacagtc
     7441 attacaaaca acgtgaaaat caattactct ccgcacaaag ataattgtag ttatatttta
     7501 actggtggag agatgcgctt tccaaaagaa gcactagtgg gcgacatcgc attaaatacg
     7561 atttcttcag tcaatgcaga catttgtatc attggctgta gcggagtcga tgtagtacat
     7621 ggggtcacaa caaagatatt aaatgaatca acgatcaacg aaatgatggt caacaagaca
     7681 atcaaatgta agattttagt cgctgatcat cgaaaaatcg gactgacatc aaagttcaag
     7741 attgctgata tttcagtctt tgattatttg atcactgata aattttgttc tgaaaaagta
     7801 ttagaggaga tcagaaatac ggggataaaa accattcaag tagattcatt ttaagaacca
     7861 ggacgtaaat atgtaaatag gattatcaaa aaaatgaata acaaatttat cgataaatga
     7921 aaaacacgct acgctcaaat tgataaagga atcccaagat gtgtccatcc aatcgatacc
     7981 atcataatct attgcttctt ttataaccgt tatatgttgc ctaaatagga atcaaacaat
     8041 atcgaaaaaa ggaggtatga caaaagtcac acctcctttt ttcgaataaa cggtattcaa
     8101 atcagaacac tgatttcaca accactttat ttcaggtcgt tttcaatcac ctttaccgcg
     8161 taatcatttc cgttgaaacg cgctattttt tttgcgtcca tatatctttc taaataatca
     8221 tcttctccta attgcttatg gcaagaagca atttcataaa gcaagtattc caatgcataa
     8281 gtcgatttat gtttcttatt atactcaata cccttctcac ataattggat tgctttatca
     8341 taatcctcga ttttacggta ataggtggcg atatcataat atacaatgca gaccatcaga
     8401 ttatcaaaat cagtctcact caatatttta agtgtacgct ccacataaac tttcgcaaaa
     8461 tctaattctc cttttgacaa gtagatcatt gccacgtttg cagctgcttg taagtgatgg
     8521 atatctgttt cggtcgtttg ttccaacact tgattaaaat aaaataatgc tgcatctggt
     8581 tttttcgcat aaagatgatc aagcagtcct tgataaaata aaatttgatt taaaagatca
     8641 gaattactta ctttttcctg atcgatcgtt tgtaaaattt tataagattc ttggtatttt
     8701 gatacagaat tcaatgattg aatctcattt atttttttcc tgattttgtc ttcttctgtt
     8761 tctactaata tatcggagat ctcgacattc agctttttgc aaagcgcact taagatattg
     8821 atgcctggcg acatattctt gttttcgata ttgctgacag ttgcttgttc acaaatgcct
     8881 tctgctaatt gtacttgtgt taaccccttt ttctttcggt attcttttag taatgctcca
     8941 tctactttaa tcaaaacaat ttccttccct ttaaaaaatt atttctcctt tatatcatac
     9001 acaaaaaaaa gttctaaaca accaaaaatg tttagaacag aataaaaatt ttaattttaa
     9061 aataatattc aaattaaaca actggcgtat ctgctccttg atttcttttt gtgttatctg
     9121 aataattatc gtttacagtt ataacacata gtgaaaattg tcatggcgag aaagtctaag
     9181 aatattttta aacataacta tttctttctt acgtgtgtat aatgacgaca gcacacctat
     9241 caattaatat aattatttta ttttttatgt tctcatgttt atttttaatg acacaacttc
     9301 tcgtatttat ctggcacaac atataaatcg atcaaaaaat tgttgcgtgt ttttttgaaa
     9361 attggagttt caacttgatt acaaaattta aatttagaag ttgtgaaaac agcgagagac
     9421 agtttaatat tcaaaatata cataggctac tcgaacgctg tgttttttag tatactagta
     9481 agaaacgaag ggatagactc attccaataa ggaggatttc atgaagacaa ttctttttgc
     9541 tcctgcagta ttcaatttag ctgagacaac acgaatgatt gaggttgcca aagctatgaa
     9601 agaccgttat tactgtgtat tctttggctt ttctaaaact tttgctcctt tgatcacaga
     9661 aagtggcttt gagtatcatt tactagcgcc gatccttacg aaaaaacaag aagaacaaat
     9721 cataaaattt gaccagttgc gtacacttaa aaaccctttt accaaagaaa tggttgcctc
     9781 tcgtatcact agtgaacaga gtctgattgc taagtttgag cctcgactga ttgtgacagg
     9841 ttcgaatgtg acaatttttt tatcggcccg caataaaaag attcctttag tatatgttaa
     9901 accctatgct ttgagtgaac ctttttttca atcagagcat gcgctgatgc cccacgagtt
     9961 acgtttcttc ggccctttaa gcaatcccct ttggcactgg acaaaaaagc gtatagtaaa
    10021 tacccgatgg atccccaatg ccttcaaaca cgctgcacaa aaagaaatgc ttcctttacc
    10081 aaaaacaagt ttacaaatga tggatgctga tctaaatctc atcacaacgc ctaaactatt
    10141 tttggaagaa gaacagctgc cggaaaatta tcgaatcgtt ggtccaattt ttgctaagct
    10201 cagtacttcc ttgcctgaag aagtgctaac ttttatacag cgaaagcaac aagaaagaaa
    10261 acgtattatc tatttcgcaa tgggtagttc aggcaatccg cgtatgttac gcaaaatttt
    10321 gttcttctta caaaaacaac cggatctagc ggttattgca cctattgact atctgcttga
    10381 tgacattcaa tctgactcag aagatctttt aataacagaa tatctgtcta gtcatctttt
    10441 gcatgaattc attgattttt cttttatcca cggcggggaa gggaccgtcc aaactgcctg
    10501 tgaatccggc aaaccgttta tcggtgtggg gatgcaattt gagcaaagct gtaatattga
    10561 ctattgtgta aaatacggaa acgcaatcgc cctcacaaaa ccagtgactg aaagaaaact
    10621 gcagattgct ctgcgcgaag tttcttcacc caagattcgt cagcaggcac gcacgctgca
    10681 agccgttttt ccaataaatg gtccacaaca agcaattcaa gaaatcgaaa ccttcctgag
    10741 caaccaccca atatagtttc aagtagaaaa agctttttta atagagactc atcagtaatt
    10801 tcgctattcg agacccagac agtgaaaata caaaaaaagt aaatagtgga ttgaaaagtt
    10861 agagttactt aaattacggt gtctaaaaaa cacaaaatca tccttaaaat aaaagatctg
    10921 acgcaatcca aatgagcata ggtagcgtct gccatttatt cttagtcaaa ttctttgaca
    10981 cctttctctg gttggatcat ctcaacgttt cttcaaaaga aagaccataa taattaggca
    11041 aatacatttt cttaaaatgt gtcatataga tctagaagca tcgctttgta gagatttgtg
    11101 ctgctagtcc cttcaacaat tactaaatca aatgtaggat ttaccacttt atctttgata
    11161 atcaacctcc ctcttctgtt gagacaatga tctcgcaatc cgatgcatac tcctatataa
    11221 actgccagca atccccacat gctgagtaga tcatgtcaga atgttctatg tcgtcagcaa
    11281 cgataaacta aaagtcacgt tcaccatgac tgattgctat tcccagcgca attatttcta
    11341 tacacgtttc atgatttgaa taaacactct catcatacat attaccattc atacaccata
    11401 ctgcagcccc tactatatgg ttgtaagctc ccaaatctat atttgccttg atcactttgg
    11461 tagtagatcg actaattctt aatccattgc tgataaaatt ttcatttttg cctccttctt
    11521 tctgccaaaa cagttaaaac aataataatc tttatgtaaa aaagggctgt gacaaaagcc
    11581 ttgtcacagt cccatattcc gaataaacgg tggtcaaaag cttgcatctg cggtaataag
    11641 ttcaaccaaa cgaaaaataa gccaacattt cacaaaaatt taagaagcaa ttttcgtaaa
    11701 tttcttctta tttcttgaag ctaaccactt ctgtcacaac cacttttaga acatttaaag
    11761 cttcgatgtg acaaaccatc tatgctgctc gatcataaaa ttgatagcaa aaattccaca
    11821 aagtacatat gtcccccatg aaaacaaaac attcatatgc ggtacaatga tctttggaag
    11881 aatcacgatc aaaaatgatg ccagtgccca aatccatcga ttgatttgaa tatgatatgt
    11941 agctagcata ttcaatataa ggtgactagc cgttaataaa aagataaaaa caaaaaataa
    12001 aatcagccaa tacattgttt cccaccttct aaaaaccaaa cttagacagt ttggacttcg
    12061 ttttctccac gactttgttc atctgacagc atctttttat cataagcttt tacaaatgga
    12121 taatagataa taaatgctat caatgtgttg atcatgatca agataacaac acgccagtca
    12181 tttcctgctg aaagataacc gccgattgga gctggtaatg tccaagttgg caaaacagta
    12241 aatctattga ccatttctaa tttgactgca aaataactga taatagtcaa aactaaagga
    12301 actaagttga acgggatgaa catgtaagga ttcaacatca taggagctcc aaaaatcatg
    12361 ggctcattga tattgaagat accaggaata atagaaaaac gaccaacctc tttcaagaat
    12421 tttgatttac agaagaatat aaacaaaaca gataccacga tcgttgctcc tgcaccacca
    12481 attgttaccg tccattgata aaactgttca ggagcgatat agggtaattg ggtggcagct
    12541 gtaccatctg ccaatgcctt tgcattctca tccaacatga tcagccacat tggacgaaca
    12601 acagccccta caatactcat gccatggata ccaaatgacc acaacaaatg gatcaaaaac
    12661 attggtagta aaacaccaag caaattattc cctaaaatat tggttaaagg ctcgaataac
    12721 gataataagg tagcgtttac atcaaagccc gcgacgcttc gaatcagcca agtaattgtt
    12781 aaaatgactg cacctggaat caatgcctca aaactacggg caacagcagg tggcacttgt
    12841 tctggcattt tgatagtaat atttcgattt ttaaagaaac gatatacttc cactgcaaaa
    12901 atcatagata agatccccgc aaacatccca gatgctccca aagaactcat aggtaagacc
    12961 cagccaagag gtgccttttc aggagttaaa acgtttacag gaacttgtaa cataaagaac
    13021 gttcctaaag ataatatacc acctgtcaca ctatctaatc catatgattt agctagatcc
    13081 gaacccataa caaaagttgc ataaatagcc atcaatccca tcgtcatcct aaaaggtaaa
    13141 acaatcgttg ccgaataagg ggcaataaat tcattccatc caggaaacgg taaattgata
    13201 aagaccataa aaaatgtccc aatcaaaatc aatgacaatg ttgaaacaac cccattacga
    13261 attgctaata aatgacgctg tgtaccaatt tttgccattg gtgggacaag tttctcttcg
    13321 acccatttca tcagcttttc cactaaaacc actccttttc aataaaatat gaaccattca
    13381 ttgcatgaca acgcaaa
//
LOCUS       DACDAF010000073        13383 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.074, whole genome shotgun sequence.
ACCESSION   DACDAF010000073 DACDAF010000000
VERSION     DACDAF010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13383
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.074"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(18..710)
                     /locus_tag="IVZ69_002049"
     CDS             complement(18..710)
                     /locus_tag="IVZ69_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP8184122.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            705..971
                     /locus_tag="IVZ69_002050"
     CDS             705..971
                     /locus_tag="IVZ69_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP8184123.1"
                     /translation="MHRTFGSRGCPTLHLADRYAERKTPTLCFAFSARTRQAGIPLED
                     IKDFLGHKDVSTTQVYAHISPEVKKRSMNQLENYIEEQIKKHSN"
     gene            complement(1147..1716)
                     /locus_tag="IVZ69_002051"
     CDS             complement(1147..1716)
                     /locus_tag="IVZ69_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP8184124.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYKTLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1790..3079)
                     /locus_tag="IVZ69_002052"
     CDS             complement(1790..3079)
                     /locus_tag="IVZ69_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184125.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFYFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLIKVLYQEWLRYVI
                     GIHDRLIEEVRYYQETLEKFPNSKDKLYQFRLAIQQALAHPAVEWGMLLLKTLQERGY
                     LDVHPPEVKIVFFFRYEHQEARRLAGVLNKTLRHRKRISIHVCTRNKPPRYADLVITD
                     HFFPLDHNEDQKTYLYHPSFGIERLLTDINYWLGKNR"
     gene            3433..4281
                     /locus_tag="IVZ69_002053"
     CDS             3433..4281
                     /locus_tag="IVZ69_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HAP8184126.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4426..5367
                     /locus_tag="IVZ69_002054"
     CDS             4426..5367
                     /locus_tag="IVZ69_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HAP8184127.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTAYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5357..7528
                     /locus_tag="IVZ69_002055"
                     /pseudo
     CDS             5357..7528
                     /locus_tag="IVZ69_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(7640..9811)
                     /gene="copB"
                     /locus_tag="IVZ69_002056"
     CDS             complement(7640..9811)
                     /gene="copB"
                     /locus_tag="IVZ69_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HAP8184128.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
     gene            complement(9831..12017)
                     /locus_tag="IVZ69_002057"
     CDS             complement(9831..12017)
                     /locus_tag="IVZ69_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HAP8184129.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            complement(12017..12226)
                     /gene="copZ"
                     /locus_tag="IVZ69_002058"
     CDS             complement(12017..12226)
                     /gene="copZ"
                     /locus_tag="IVZ69_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HAP8184130.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12239..12679)
                     /locus_tag="IVZ69_002059"
     CDS             complement(12239..12679)
                     /locus_tag="IVZ69_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HAP8184131.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(12753..13292)
                     /locus_tag="IVZ69_002060"
     CDS             complement(12753..13292)
                     /locus_tag="IVZ69_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HAP8184132.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3751 a         2806 c         2386 g         4440 t
ORIGIN      
        1 aaagaggggg ggatttttta tcgttgtgga atatttaaat accaacgctt gtcatgaaaa
       61 tcttgtgctc cacccttagt atttccttct ggatcgtttg tcgcacgcat catgacgtat
      121 actttcttat tagggaaatc acgcatattg aaagatacat gatagccaac atttcctaaa
      181 gtattataag cttgatttac gtctggtcta taaatcccat cagctcttac tctagctagt
      241 tcttttccag tattgtagtc cataatgaaa atatactcgt atttataatt agcaatgtgc
      301 catccagcta catgcaagtt tgcgttttcg atttctccga actgatcaat gtgggcgtaa
      361 tttgttccat ctgtcagcgt agaatttgca gcacctgctc gagttggatc aattactggt
      421 ttatcctccg aagtagttgg attatcatcc gtaaaaccat gagccaaatc ataggctagt
      481 ttttctttac ttacacccat ttcagaaaga taaccgtaag gatctgtatg atcgccccaa
      541 atattttgtg ttacccataa atgcgatttg attcctggtt ggttataagg agtgtctaat
      601 gttaatggaa taccatattt cattgctgaa tctcttgcca attcaacgta tactttatag
      661 ttcttttcaa aagtttcttt atcatgtgtg tgttgtaact cgatttgcac aggacttttg
      721 gctcacgagg ttgtcctact ctacatcttg ctgatagata tgctgaaagg aaaacaccaa
      781 cattatgttt tgctttttca gctagaacga gacaagcagg aataccttta gaagatatca
      841 aagatttttt aggtcataaa gatgtttcca ctacacaagt ctatgcccat atttctcccg
      901 aagtgaaaaa aagatcaatg aatcaactag aaaactatat agaagagcaa ataaaaaagc
      961 actcaaattg agtgcttttt taagctcact atcactaaaa ctatcactaa ttttatttat
     1021 aagcgaacat gtttctatca ctgatttttt aaatctagcg aaaaaccctt atcttaaagg
     1081 cgttcgttca attctttggc aaggtcttca aagcctggct tgcctagaag tgcgaacatg
     1141 gttttcttat agctcatgta gaaaaatttt cttgatgatg attttatcca tcaattgaga
     1201 ttgactgttt tgctctccta tgatttcagc tatgattgtc cgattttgcg gttttcttct
     1261 taactggtag ttgattttcc cagtttccat caactcgcta agcatatcca cgactccgcc
     1321 aaatccggtc tttttcgtaa taaaacctag tgctaccatt cgttcatcta gattttttgc
     1381 tgtaatcgtc acaccagtaa tgagcgagtg ctgtaatgtt tgggccagct cttccatccc
     1441 ttcagcattg gatacgacgg aagctgtttt gttaataggt tcttcgttta tttcttttgg
     1501 ttctttcctc tccactttca ctgtttgacg aaggacatct agttcttgca agagcgtttt
     1561 gtattgttct tgggtcagca tcacgccagc tactttttca cgattaaata tatatacgcc
     1621 agttcccgcg tctcgcgctt gagcaaatac atccatcggc gatcgtttca cttctgtgat
     1681 cgaagatgtg ggaacttcta atttctttaa ttccaatgga tttcctcctt tactaatcgc
     1741 tttttattat agcacagact gacttgtttt gatctttttt ccaaaggttt tatcggtttt
     1801 tgcctaacca gtaattgata tcggtaagaa gtctttcgat accaaatgaa ggatggtaca
     1861 gatacgtttt ttgatcttcg ttatggtcta gtggaaaaaa atgatcggtg atcactagat
     1921 ctgcataccg aggcggctta tttcgagtac atacatgtat agagatccgt tttcgatgtc
     1981 ttagcgtttt gttcagtacc ccagcaagtc ttcttgcttc ttggtgttca tagcgaaaaa
     2041 aaaagacgat tttcacttca ggagggtgga catctaaata ccctcgttcc tggagtgttt
     2101 tcagtaaaag catcccccac tctactgcgg ggtgtgcaag tgcttgttgg atcgctagcc
     2161 gaaattgata tagtttatct ttggaattgg gaaatttttc taatgtttcc tgataataac
     2221 gaacttcttc tatcagccgg tcatggatac caattacgta acgaagccat tcttggtaaa
     2281 gtacttttat cagctttgat ttgctttcgc tctcaaattc gctattcagc caaaacagcg
     2341 aatcaagctt ttcagtcaca atcgtcaatt tccgatagtc ttgtgtctct tctatccgtt
     2401 tccaccgctt ttcagtaatc tggttacagc tcaagcgcaa aattgctaga taattttttt
     2461 cttttattgg caaaatctgc tcctctctaa atagcaattc aggaaacaat tcaaagaata
     2521 gtgttcgact gtctcctaaa atctcgattt ctgccggatc ctttctttgc ttcaataatt
     2581 ggatgaacat ctcagaaaag gactgctctc catcatctgc aaaaaaatgc ggaaaatctt
     2641 tcaaaaagta aaacagcaga tatcttactt ttctttctga accaaagatc tgtgcttttt
     2701 tataagaaaa agaaaggtgg tactcgccaa accactttct caatcgctct tgcgtagaac
     2761 gatcgtactt ctgctcgtaa ggttcattta atagcagatt tttcagtaaa caaaacgggg
     2821 gtgattggat cagaaaaaca aacaagagat aaggttcgct atatccttga tcataaacta
     2881 actgaacggt tttcttatga agaatcagct gaatgggaca gtcgctttcc gccaaacgtt
     2941 tcagatgccg atccactgtt ttaacatcga ttttcagttc ttcagctaaa tcagcttttc
     3001 gccagatcaa atctttcatt agattgatta gtgaaaataa attctgtgca ttttttgata
     3061 atagtttttg ccatctcatc gatcatttct cacctgattt ctaaacatat tgtttgatca
     3121 aaatgagttc actcctaaaa agataaaaaa ctccctttct atttatttaa atacgcaaat
     3181 cttcctcatt attttttatt ttactcaatt taatcgtatt ctcatttcaa aacgaatgta
     3241 ctttaaaaaa acataataag atcactttgc ttgtaggatg tattcccttc cattacaatg
     3301 aaataaatag cgattttatg agaaggtgat gtgaaaatgg aagaaaaaat agaagaatcc
     3361 aaacaaaaaa tcgatcagtt gatataagaa ttagaaaaag cggtcatcgg caaacgttca
     3421 actatccaat tgatgatcgt ggccctatta gcaggtggtc atgtcttatt cgaagatatt
     3481 cccggtgtag gtaaaacgtt actggtcaaa gcactagcaa aagctgtaca gggaaccttc
     3541 agcagagtcc aatgtactcc tgatctgctg cctagtgata ttcttggttt ttccgtatac
     3601 aattcacaat caaaagagtt tgaatttcgt ccgggaccga tctttaccac gatcttgttg
     3661 gcagatgaga tcaatcgtac gactcctcgt actcagtcag cacttttaga agcaatggcc
     3721 gagaatcatg caacgatcga caacaataca taccctctag acaatcattt ttttgtctta
     3781 gctacgcaaa atccaatcga gtacgaagga acatatcctt tgccggaagc acagctcgat
     3841 cgttttttat tccgactaca aatcggttat ccttcttttg atgacgaact tttgctactt
     3901 ttggataaat tcgaaaaagt gttggataac ttaaatgaag tattgaacag ttatgaaata
     3961 gaagaaataa aaacaaatgt ggcgaatgtc tttgtcagtc ccgaagtggc atcttatgcc
     4021 ttgcagttag tgtcagcaac aagaagtcat gctgccatcc agcttggcat cagtccacga
     4081 ggaagccttt cctttattca ggcagcaaaa gcttatgctt taatccatgg gagaaattac
     4141 gtcacgccca aagatttgca ggatttagtt ccttacgtgt tttcccatcg cctgattttt
     4201 tacgatcgtt cattgaagga agacgaaaag aaacaaatca ttcatactct tgttgcacaa
     4261 attcctattc ctgtgaggta gattgaggta gacaatggaa aaaatcaaag attatttcat
     4321 taattttgtg ttatttctgg tatatttcat cattgtgctt tttgctcttg tattcaacaa
     4381 ttctttaggc tggttcttgt tggccttttt tactctttat gtatcatgga gcttgatttc
     4441 attaagcagc tttctaaaga aactttcggt tacttgtaca ttgcagccac tcgtttatcg
     4501 caaaaaaagt atgcaggtta ttttttccat agcaaaaaag agaacttttt ctttacctct
     4561 ccctcgttta caaatcggct tcccagcaat ctttgcagaa aaaaacaaga gattttgatt
     4621 cttacaaata aaccgcaaga agtccaattg ctttggcagc caaaagaaag aggatgccat
     4681 gaaacattaa ctgtcatttt tacagcctat gatagtctag gacttttcag aaaaagtgca
     4741 aaaagagaga tctcttttcc tgtgactgtt ctgcctgctt tttgtaagat tcaagcagaa
     4801 aaattacaga gagttctgga aaaaaaacag cagctgaacg cgtaccaaag aggtcttgat
     4861 tttcgggaac atcgcgctta tcgtccaggt gattctttca accgaatcga ttggaaattg
     4921 tctgctcata ctcaagagtg gttataccgt gaatacgatt atcaagaaga agaatgttct
     4981 cctctttttt gcttttgggg ttcgcccagt ccaaaatttg aacctctgct agacttgtat
     5041 ttttctttat ggcatttgag aaaagaaaag cagccggaac ttctgatatt aggcaaccgc
     5101 gcctttcatg gcaaagaccc cggtcatacc tattttgctt ctttggaagc tggcgatgag
     5161 aaagcttttt tcgcacactt gaaaaaatat gcaaaaaaac aaatcgtcct ctttgttcct
     5221 gagaattctc ctgaagtctc agaagctatt gaaacattgt caaaagatcg aacggcttat
     5281 cttgtttatt tcgtagaaaa acaactcatg gtccaagaaa aagacaagat atgttcattg
     5341 ccaggaggtg aatggattga cgattaaacg ggaaaaatgg ctgcgtggcg tttactcctt
     5401 tgtgatacta agtgtaggtg ctccgatatt tgtagtagct aatcaattgc aaaacagcta
     5461 ccttcttatc ctaactattg gtgtcctatg ccttattgtc tgctgtattc ctaaaaaatg
     5521 ggtacgtttg ctgctttctt tgccagtaat gataggttgt ttgtttttat attttccttc
     5581 gaagacattt tccatattat ggatcttaca gtttttttcg tcagttacag aggaattctt
     5641 ccatctatcc caaggtaaac tttattattt gccagaaaag acagcttttt ttctcataat
     5701 gttgctgatc tatttattta ttacattgac cgtggattac gactattggt acgcaccctt
     5761 tctttctttg atggcttact tcatgatgct taccgttttt cggaaaaaag atttactgta
     5821 cgaaatgatt gcggtagtaa ctgttttgtt cgtgtatctg gcagcaaggc aatttttctc
     5881 catccggttg ttgtcgggaa acactcgatt ccagtcattg actacagttc tgcttatttg
     5941 tttcttaact tttagcgcta tcttgccttt atatcttccg aaagtacacc aatctctcga
     6001 ggaaacgagt gaaccgatcc gagaatatct taatgatgaa gggctttatg acacactcca
     6061 tgagtatcaa ttaaccggaa gtgcaagaac aggcttcagt gagaatgatg aacagcttgg
     6121 tggaccttta tatgataatg gcgaagttgt ttttacagcg aaccaaaaag gaaatggcta
     6181 ttggaagatc gaaaataaaa atcattacac cggttctgga tggatagaag atcaggacgc
     6241 acccatccaa ccaatccaag aattccctgt tgacatcacg agctaccaaa ccgttataga
     6301 agacaaagaa aacattacat tgaccctaaa aaaacaagct ttcttacctt atccttatgg
     6361 aaatactacc ttgactgatt tttcattagc tagtggacaa acgctttact atttgcctga
     6421 aagccagcga ttcattcctg tcccgaatga atcgacacgt tctgcaactt tacaaacaga
     6481 aaggttagtt tttacgagag aagaattaaa aagcagtcag ttaaaagctg atgatttaga
     6541 aaatcagcag acaaatcttc aattgccaaa aagtttgcct aaacgtattg aggacttggc
     6601 ggtcgaattg accaaaaatg aagcaacttt aattcgtaaa gtcgaagctg tctaacagta
     6661 tttaaaaaca agcggaaatt tccgctattc caaaacggat accgggcata ctccgaaaga
     6721 acacgattat gtggattatt tcctctttga ttcaaaagtc ggctattgtg acaacttttc
     6781 aacttctatg gtcgtccttc ttcgaacact tggtatccca gctcgctgga caaaaggttt
     6841 tacaaatggg ctcagaacag gcacagataa tcaagggaat gaggaataca gcattctcaa
     6901 tagtcatgct cattcttggc cagaggtata ctttcctgga tttggctggc ttccatttga
     6961 accaacccct tcatttgcca atccaatggg ttcacaacca gttgctgaaa caaccgaaac
     7021 cgtccagcct gctatcgaac aaccaaatga aagcgaaaat atggcagaaa ctatttccag
     7081 tgagagatct gaggtcattc catcagaaga aacaacactc acaccagctt ataaaatcgt
     7141 cttattcagc cttggagtgt gtttatccgt cttgttgttc tttctattgt tattcagaaa
     7201 atctctgcgc tggacaagtt atcttatcta tcttcatttt tttgcttcta ctaatacgat
     7261 tgcatatcaa aaacttctta accctttgga aacattggta ccgcgcaaac ccgcagaatc
     7321 tttgcaggaa tatagcctgc gaatagaaca agaattcaag ctagatctgc gtttcattcg
     7381 attaactact caatatgaag cagaaatata tggacgacaa gcagatccgg taaaattcga
     7441 taaaaaaacc tatttagaaa taacgcgtat aataagaaaa acggtataca aaaaaattct
     7501 gacaaaaggg agccgcttca aaaaataaga taaaatttct ggagaatcta cttctggaat
     7561 gccgagaacc agctgattga gtatcgatta ctcgaaaaaa aggttgtgac acgttttttg
     7621 tcacaacctt ttttcattat tatttgattt tcaatgtcaa agcatttaga gctacaacta
     7681 ccgtacttaa cgacatcaag acagcaccaa ctgctggact taatatgata ccaattggcg
     7741 caagaattcc ggctgctagc ggaattgcaa gaatattgta acctgccccc caccagaggt
     7801 tctggatcat tttctttcgc gtttgcttgg ctagatcaag aaaatgcaaa atatcttttg
     7861 gatcgctgtt tgtcaatacg acatccgcag aatcgattgc gatatctgtc cctgcaccga
     7921 ttgccatccc gattgaagca cgggctaaac ttggcgcatc attgatccca tcacccacca
     7981 tgattacttt tttcccttgg tcaaggtatt tctggacaac agcttcttta tcatctggta
     8041 ataaaccgcc ataatattct tcgatcccta aataatctgc tactgcttgg gcagcgtttt
     8101 tattgtcacc agtaagcatg acaggagtga tttttctttc tttcaatgtt cggataaatt
     8161 cttttgcttc tgtttttact acgtcaccta aagcaacgat tgcagctaga tgattttcta
     8221 aaatcaggaa gctgatggta tttccttgtt cttggtaagg tttcaataat gcttgttcta
     8281 cgtttaatcc gagacgctca acttcttttt cattaactat tttcacttgt tgttttttga
     8341 ctgttgcctc tagcccgact cctgaaagat tttttagatt ttcagcttga taaggcttga
     8401 tttcatgttc tttcaaataa ttcataatgc caacagccaa tggatgattg gcattcgctt
     8461 ccaaggctcc tagatattga aggatttcat ttttattgaa cgcatcatca agtacttcga
     8521 cacccgttac agtaaatttt ccttctgtta gtgttcctgt tttgtccagc atgatcacat
     8581 ctagatcatt ggcttgctcc agtgcattgc ggtttttcaa aagtaatccg tttttagctg
     8641 ctattgatgt ggagcgagca acaactaatg ggatagctaa acctagagca tgaggacagg
     8701 cgatgataaa gactgttacc atacgttcta atgcattagg aagatctgtc aagaacaacc
     8761 aggcgatgaa tgccaggata cccacaatta atgcgacata aaacagccat tttgccactt
     8821 tgtcagataa tgactctagc ttggattttt ctccttgtgc ttttcgcacc atttccataa
     8881 ccttcgctag ataaccattt tcaccagttc cagttacttc gatttcgatc gttccatccc
     8941 cattgataga accgccaatc actttgtcat tggcttgttt tttgattcct cttgattcgc
     9001 cagtcacagc tgattcgtca acaattgttt cacctttcaa gattacacca tctgttggca
     9061 ttttatcacc agaccggacg atcaaacgat caccttcgtt tacttctttc aatgaaactg
     9121 tctcttcttt tccatctttc gtcaagcgtt tcactgattc tggcagtaat tctgctagtt
     9181 tttgtaaagc attgctggca ttcgacacag cattcatttc aatccagtga cctagtagca
     9241 taataacgat caaagtagcc aattcccaga agaaatccat gacgtgtgta tgtggattga
     9301 gcagatttgc gataaacgaa tagacactat aaatatatgc aactgtaatc cccatcgcga
     9361 tcagtgtcat catagcagga cttttttgtt tcaattccat cttagctcca cttaaaaatg
     9421 gctgaccgcc atagataaat agtatagttg ctaagatcaa tacgagccaa tcagaaccag
     9481 gaaacgttac ttgaaatgga aattccattc ccatcattgg tgaaaaaaga atgattggga
     9541 tagctaggat aagcgatagc caaaattttt gtttgaaatt ccccatgtgc atggaatgat
     9601 ccatgccgcc gtgttcgtga tccatgtgca tcgaatggtc catttgtttg ctgtttgcta
     9661 tatctccatg gttatgtccc atgtgcatgg aatgatccat ctgactatgg tcatgtttca
     9721 tctccatctg tttttcatga gattctgtac tttctttgtt tactacttct tttttatgct
     9781 catgtttttt ctccatatcg ttcccattca tttttactcc atcccttctc ttactttttc
     9841 atgtgtcgat ttaagctcag ggagttcaac aatacactga cggaactaaa cgccatcgct
     9901 cctcctgcaa tgattggatt caaaaagcct agtgcggcaa aaggaatacc aatcgtatta
     9961 tagacaaaag cccagaaaag attttgtttg atttttctca atgtcaacct agacaactcg
    10021 attgtttgtg caatggatgc caaactgcta ttcatcagcg tcacatcggc tgtttccatc
    10081 gcaatgtccg ttccacttcc cattgccata ccgacatcag ctaatgctaa ggccggtgca
    10141 tcattgattc catcgcctgc cataccgact tttttgccat ctttctgaag tttttctacg
    10201 taggctgctt tatcctctgg aagtacttca gcaaagatat gctttggatc aataccaact
    10261 tgtttaccaa tcgtttcggc tgccagtttg ttgtctcctg tcagcataaa aacatctaat
    10321 cctttattct ggagctgctt gattgcttgt ttggcttcta gtttgatttg atcagccacg
    10381 gcaatccacc cgatcacttg cttttcatca gctaaaaaca tgactgtttt tccctgctgt
    10441 tctaattcta acgcgtgttc ttggtattca tcaaatgata ggttcaattc aattaatcgt
    10501 ttacgtgtac ccgcaaaata gcgtactcca ttaatcgtac cgctgatccc agcacctggg
    10561 tgggctgtaa aatcaatcat atcgtatgtt gctgcttctt gcagttttcc gtattccacg
    10621 attgctttac ctagtggatg ttcagaagct tgttctaaag tataaaaaat agataggact
    10681 tcttttgaac cgactagatc tgtaactttg ggctttcctt ctgtaatcgt tccagtttta
    10741 tccaaaacaa tgctgtctaa gtgagcagct gcttctaatg cttctccgcc tttaattaaa
    10801 attccatttc gtgcaccaac acccgttcct accataatag ctgttggggt cgctaaacct
    10861 aatgcacatg gacacgcaat gactaataca gagacactat ggatcaatgc gagttgccaa
    10921 tcaccagtga tcaaacctgt agctatgagc gtgataaacg cgatgactaa tacgatcgga
    10981 acaaaaatcc ctgagatccg atctgcgatt ttttggattg gggctttgct cccttgagca
    11041 tcttccacca tttgaatgat ttgcgctaat actgtctgct tgccgacttg tgtgacttcc
    11101 atgtgtagca gaccattcgt attgattgtc ccgccaaaaa gcgtgtcatc cggattcttt
    11161 tctacaggaa gattttcacc agtaagcata ctttcatcta tcgcactgct tcctgaaata
    11221 attcgaccat ctgctggaat ctgctcacca ggacggatga ctagttgatc accaacgact
    11281 acttcttcaa tcgctaacgt ttcttctttc ccgtttctta tcacttgggc ggtttttgtt
    11341 tgaagagaca tcaattgttt gattgcatta cctgttttcg tttttgctgt atgttccaaa
    11401 tatttgccga gcaaaatcag cgtgatgatc atactgctgc tttcaaaata aagatcttgg
    11461 gggtgtccac ggaaaaatcc gttgtaaatg ctcaatgcaa aggcagccga tgttccaatt
    11521 gctaccaata catccatatt tggtgctttc gtcttgattg catggtacgc acctttataa
    11581 aaacgagcac cgacataaaa ttggacagga gcagacagca ctaactggac gattggaaaa
    11641 tgaaaaaagt gaacaatcgc cgcatggctt cctaacatca tagcaatcat tgacaacatc
    11701 aacggcaaag tcaaaaccgt actcaatata agatcgaata gcattttttt caaatacgct
    11761 tgcttttctt ctgcaatttt ttgtttgtgg gcttcatcgt acaaaattgc accataaccg
    11821 atgttttcta cgctttggat taatttttca gtggtcgtcc cttcatattt gacacttgct
    11881 ttttcagtgg ccaagttgac tgtggcattg accacaccag gttgtccgtt cagctctttt
    11941 tcgatcctag cagaacaatt tgcacaagtc atacctgtaa tgacgaacgt atccattttg
    12001 gtttctgctg ttgccatcaa atcacctctg ctttataacc caatccattg attgcttgac
    12061 aaatcttttc ggattgaact tttgtttcat caaacttgac cgtaccgttt gcttttttca
    12121 aatttacttt cactttttgc acgccgtcaa gtgcgcttac tgtttcttct actcttgctg
    12181 cacaatgatt gcagctcata ccttcgattg aaaattgttg tttcattttt tcttcctcct
    12241 attgatgttg tttacattca cattgacctg ggatacagtt acattcgatc gtatctactg
    12301 gttgcttttg ttccagttgt ttcaaaatct cattgatatc ttcttgagtc aaagtggctt
    12361 cttctactag atccgcaatc gtctctccaa tcctttttgc acagatatgg gaaaaaagat
    12421 tttccgtcgc actgcgaact gtttccatct ccgagacagc tggatgataa atgaattttt
    12481 ttccttcttg ttctgtccag atcacttctt tttttaccaa acgtcccagc aaagttttga
    12541 tcgttgctgg tttccaatcc atcgaatcag ctaagatctg cgtgatttct tgggctgtcg
    12601 tctgtccaag tgtccaaata acacgcatga tctcccactc tgaatcactg atctttactg
    12661 gcgttttgac tttttccatt tatttcacac ctttcgttta caaatgtaat cattagctta
    12721 tgaatacaga ttacgcttgt aaacaaaaac tgtcaattat ttttgctctc tattttcaat
    12781 ttagttaaaa attcttgttt ctctcgtctt gttttaagga tgatcagttt atttcttgca
    12841 ttagctactt ggatcagctg ctgtattttc ggttcattgt tttcttcaaa atgccagata
    12901 aaagataaaa attctaagta ttccctgttt agtttctctg aaaatgattc aggcatatct
    12961 ggccgagatt ttttgtttat ctttcttttt agagaacgcc aaactactcg gtagatggcg
    13021 agataacgcg gcactttaag ccaaatgatc ttatctgctt ctttaatcct ttcctctaat
    13081 gtagaagtat aatttccttc aacaatccat gacggattag ataccataaa cgattgctgt
    13141 tcttgcaaaa accacttttt tgcctgaata ctgtagtctg ttgtatgcca taaaaggtct
    13201 agcggcagta gcggaaagtc ggtgatttct ttgatcttcc ttgcgagggt cgattttccc
    13261 gacccacttt gtccaatcac gatgatcttc attcttctcc ctcacttctc tttggaattt
    13321 ggttcgatca taccacttat aacgccgcaa aaaaacaagg gactgtgaca aaagtcgtgt
    13381 caa
//
LOCUS       DACDAF010000074        12875 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.075, whole genome shotgun sequence.
ACCESSION   DACDAF010000074 DACDAF010000000
VERSION     DACDAF010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.075"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            11..733
                     /locus_tag="IVZ69_002061"
     CDS             11..733
                     /locus_tag="IVZ69_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP8184133.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
     gene            791..2830
                     /locus_tag="IVZ69_002062"
     CDS             791..2830
                     /locus_tag="IVZ69_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HAP8184134.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(2939..4090)
                     /locus_tag="IVZ69_002063"
     CDS             complement(2939..4090)
                     /locus_tag="IVZ69_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HAP8184135.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(4244..4774)
                     /locus_tag="IVZ69_002064"
     CDS             complement(4244..4774)
                     /locus_tag="IVZ69_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184136.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(4873..5223)
                     /locus_tag="IVZ69_002065"
     CDS             complement(4873..5223)
                     /locus_tag="IVZ69_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HAP8184137.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(5380..6909)
                     /gene="ahpF"
                     /locus_tag="IVZ69_002066"
     CDS             complement(5380..6909)
                     /gene="ahpF"
                     /locus_tag="IVZ69_002066"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HAP8184138.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(6919..7482)
                     /gene="ahpC"
                     /locus_tag="IVZ69_002067"
     CDS             complement(6919..7482)
                     /gene="ahpC"
                     /locus_tag="IVZ69_002067"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003756453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HAP8184139.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(7626..8288)
                     /locus_tag="IVZ69_002068"
     CDS             complement(7626..8288)
                     /locus_tag="IVZ69_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8184140.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            8472..10118
                     /locus_tag="IVZ69_002069"
     CDS             8472..10118
                     /locus_tag="IVZ69_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HAP8184141.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            10109..11191
                     /gene="uxuA"
                     /locus_tag="IVZ69_002070"
     CDS             10109..11191
                     /gene="uxuA"
                     /locus_tag="IVZ69_002070"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HAP8184142.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(11299..12852)
                     /locus_tag="IVZ69_002071"
     CDS             complement(11299..12852)
                     /locus_tag="IVZ69_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8184143.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
BASE COUNT         4308 a         2364 c         2385 g         3818 t
ORIGIN      
        1 attatctatt ttgttactgc ttacattagt agttggctat ttttcgattg agtttatcca
       61 tggattttcg tctgcaaaac agagttcaac tgtgaaaaag gtagagccga aaagtatccc
      121 taccacacta aatgtggctt tgattggttc agatgctcgt tcgaaagacg aaaacggtcg
      181 ctcggattca cttctggttg cacaatacaa ccagaaaaca caacaagcaa aactgatctc
      241 tatcatgaga gattcatatg tcgatattcc aggttacgga atgaataaga taaatgcagc
      301 ttactcttat gggggagttg atttattaaa tcaaacatta aaggaaaatt tcaaatttga
      361 agctccctat tatgcaagta tcacatttca agattttatc gattgcgtta atgaactgtt
      421 tcctggtgga gtcaagatcg atgcagaaaa atctctagat ttagatggcg tatatataaa
      481 caaaggagag caagtgatgg atggtaatac tttactccag tatgctcgat ttcgggaaga
      541 caaagaagga gacttcggga ggatcagaag gcagcagcaa gtgatcaaag ctatctctca
      601 gcagctgaaa gacgtaactt caatattcaa gctacccaaa gcggttggga aattacttgg
      661 tagtatccaa acgaaccttc cagaaagtgt gcttctggat tgtggtatgg atttcctcaa
      721 agacatatgt tagaataaac aggtataaat agtgaaataa aggaatgaca agcaagagaa
      781 ggaggaaaaa atgaaaagaa gtgacaagca cggcaaaaat cgaacaggcg cttatattgc
      841 cggcgcagtg atcttaatag cagctgcggg tggcggttat ttttactacc agcactatca
      901 agaaacccaa gcagtagaag ctggagaaaa gacagttgag caatttgtcc aagctttgaa
      961 caagggagat tataacaaag ctgcagaaat gacatcaaaa aaggcggcaa ataaaagtgc
     1021 attatctgaa aaagagatct tagataaata ccagaatata tacggtgctg ctgatgtcaa
     1081 aggacttcag atatcgaatc taaaagtaga taaaaaagac gattctactt acagtttttc
     1141 atataaagca aagatgaata cctcattagg tgaattgaaa gatctttctt ataaaggaac
     1201 attagacaga aatgatggtc aaaccacgat caactggcaa cccaacttgg tttttccaga
     1261 aatggaagga aatgacaaag taagcctgac cacacaagaa gcagcaagag ggaatattat
     1321 agatcgaaat ggtgaaccat tagcaacaac aggcaaacta aaacaattag gagtcgttcc
     1381 aagtaaactt ggagatggag gcgaaaaaac agccaatatc aaagcgattg cttcctcctt
     1441 cgacttaaca gaagatgcta tcaatcaggc gatttcacaa agctgggtac aacccgatta
     1501 ctttgtccca ttgaaaatca ttgatggagc aacgccagaa cttccagctg gagctaccat
     1561 tcaagaagta gacggcagat attatccttt gggtgaagca gctgctcagc tgattggtta
     1621 cgtgggagat atcacagcag aagatattga taagaatcca gaattaagca gtaatggaaa
     1681 aatcggtcgc tcaggtttgg agatggcttt tgataaggat cttcgtggga caacaggtgg
     1741 gaaattaagc attacagatg cagacggtgt agagaaaaaa gttctgatcg aacatgaagt
     1801 tcaaaatggc aaagatatca aattgacaat cgatgcgaag gcacaaaaaa cagcttttga
     1861 cagtctagga ggaaaagctg gatcaactgt tgcgacaacg ccaaaaaccg gtgatcttct
     1921 tgcgcttgct agctctccaa gctatgatcc aaacaaaatg acaaacggga tctcacaaga
     1981 agattacaaa gcttatgaag aaaatcctga acatccattc atcagccgat ttgcgacagg
     2041 ttatgctcct ggatctacgt ttaaaataat tacagcagca atcggtctcg acaacggcac
     2101 tatcgatcca aatgaagtgt tgacgatcaa cgggcttaaa tggcaaaaag acagttcttg
     2161 gggatctttt caaacaacgc gtgtcagtag tgatgtatca caagtagact taaaaactgc
     2221 tttgatctat tccgataata tatatgcggc acaagaaacg ttgaaaatgg gtgagaaaaa
     2281 atttcgtaca ggcttagata aattcatttt tggtgaagac cttgatttgc caattagtat
     2341 gaatccagca caaatttcta atgaagatag ctttaactca gatatcttgc tagctgatac
     2401 tggatatgga cagggcgaac ttctaattaa tcctatccag caagcagcaa tgtattctgt
     2461 ttttaccaac aatggcacac ttgtctatcc taaattgatt gcagataaag agacaaaaga
     2521 taagaagaat gtcatcagcg aaacagcagt acaaacgatc gtgccagatc tgagagaagt
     2581 tgtgcaagat gtaaatggta cagcacattc tctttctgct ttagggattc cgttggcagc
     2641 gaaaactggt acagcggaaa tcaaagaaaa acaggatgta aaggggcaag agaacagttt
     2701 cttgtttgct ttcaatcttg ataaccaagg ttatatgatg gtcagcatgt tggaaaataa
     2761 agaagatgat gattcagcaa ccaaacgagc atcggaacta ttgcaatacc tcaaccaaaa
     2821 ttatcaataa aaaattgctt tttaagtaca gtaaaaggac tgtggcgtta tcgtcacagt
     2881 ccttttttca aataaacggt tttcacgatg tctctttcac aacttctttt tgatttactc
     2941 acacttcata aacttttttt gtaaaatatt tgagaacaag tggagaaata agtgtactta
     3001 ataaaatcac gataactaaa ggtgaatagt actgtggttc gatcaattga ctttgctgtc
     3061 caatttgtaa aatgatcaaa gccatttctc cacgcgaaat cataccagca ccgaccatca
     3121 atgaactatg ttgagaaaaa ccggcaatct gagcaccaaa ataacctcca agcaatttgg
     3181 tcaaaatcgc tacaagcgtc aatatagaaa taaagagtag ttgttcacta aagtcagaaa
     3241 aatcaacttc taatcctaca ctgacaaaaa atactggtat aaatactgca tatcctaaag
     3301 cctctacatt gtggtatact tcttctttaa cctttgtctg actgacagct atcccagcaa
     3361 aaaaagcacc aatgacagag ctaagcccaa caagatccgc tacgtaagac attcctaaac
     3421 aaataactag cgatacgatg ataatagaag aatttgcgta cactttttct gcaaatgaaa
     3481 gtaggaaagg cgcaatccat ttgactaata agaaaataaa aacaaaataa attagctgtt
     3541 caatcaaaac aagcggtaaa gaagcattgc tagaagcttc ccccgttaga aaagataggc
     3601 tgaaacttag aactaaaacg actaaaatgt catctaccac agaagcaccc aaaattgttg
     3661 atccttcttt tgtattcact acgtttagtt cttttaatac ttctactgaa atactgacag
     3721 aagttgccgc aagaataatc ccaaagaaaa tcgcttcatt tcccgaaact tggaatgctt
     3781 tgcctgtcaa ccagccaaaa acaaccggga agatgatccc aagcaaagca acgaacatac
     3841 caggtcggaa atattttttc aaaagagata aatcactttc cagaccagct aaaaacatta
     3901 ataagatcac accaatctcc gaaaagtcat ggactagaat atcaggtttg acccaattca
     3961 atccagcttg gcctagcaaa acaccaacaa gtaattgtcc aatcactgct gggataccta
     4021 atctccgcga gatatgtgag ccaatcgttg ttgaaatcaa tatcaggcat aaaataccaa
     4081 taaattccat tctcatcatt cctttgtata aaatatagcc cgaacttagc ataacataca
     4141 ttattgaaaa aataggaaaa tatactcaca aaaaaaccaa caatccaaaa gatttttttg
     4201 gattgttggt ttttatacgg tctattttaa taactaaaaa tgattaacgt atagtcattt
     4261 ttcttattct gatgaaattg ataatctcct ggatgcccat gaaaatcaaa ataaagccga
     4321 atatttggaa tagaagcatc aaacttttga atggattgaa caataagacg aatccgccaa
     4381 tcaacaacag aatactacta taaacactcc aacttttagc ttttgtattc atgctgaaga
     4441 acaactggaa caagctgttg atgataacag ctaatccaag aagaatcggc aggatagaaa
     4501 cgattgcagg tgcaaaagca tagacgatca gagctaagat caggaaaaaa agaccactga
     4561 acagaccgat actccaagaa cctgttttcc ttttaaaacg gtaagcctca aaaagattca
     4621 acaacccaag caaaacaaga taggcggtga tcagataacc gataaaatga aaaacagcag
     4681 aagggtttag cacaatcgca atcccagaaa taatataaac agcagctctt aataaggcgt
     4741 atttttgaat attttgttta atcgtctcaa acatataaga aaacctcctt tgacttattt
     4801 taacgtgaac tagtcatttt accaaattaa atgttacaaa atgagcgaag gagaagaata
     4861 tctctggaaa aatcaacttc tgaggatctt ttccattttt ttgccttttg ctagctcatc
     4921 gatcatttta tctaaataac gaatttcttt catcaagtta tcctcgatgt cttctactcg
     4981 tacaccacaa acaacacctg taatcaagga acgtgaagga ttggggacag gggcttccgc
     5041 aaaaaattgt tcgaaagtca cttgtttttg tagttgatat tctagttctg tttgggaata
     5101 acccgtcagc caacaaatga tttcatctac ttcctctttt atacgatctt ttctctccgc
     5161 ttttgctaca tacataggat aaacgcttgc aaaacttgtc gtaaaaatac gattttgcgc
     5221 cataatcagt cacctttctt tttttcaaat tatttactac ttatagtata taagaaaaag
     5281 agaagaaaaa gcgattattc aaaaaaacaa aaaggattgt gacaaaattc ttgtcaccat
     5341 ccttttttcc gctctctgac tttttacaat cttcatagct caagtgcgca tcagataatc
     5401 gaatgctcct aaagctgcag tagctcctga acccattgaa acaatgattt gtttgtatgg
     5461 actatctgta caatcaccag ctgcgaaaac gccggggata ttcgttgcgc catttttctc
     5521 ggtcactatt tcatttcttg gattcatttc gatcgttcca tctagccaat ccgtattagg
     5581 gagtaagccg actagaatga atactcctga aacagctagt gtatgcatct ccatcgtacg
     5641 gcgatcgata taggagagag attctacctg attcgtaccg ctgatttctt tcgtcgctgc
     5701 atgtttgata acagtgacat tcgcaagaga gactagttta tcctgtaaga tttgatctgc
     5761 ttttaattct ggtaagaatt ctagaacata tacatgtttt gctaacccag ccaaatcgat
     5821 tgctgcttca acaccagaat taccaccacc gataacagca atctcttttc ctttaaataa
     5881 agggccgtca cagtgtgggc aataagcaat tcctttattt ttaaactctt tttcgcctgg
     5941 tacattgata gaacgccagt gcgcacctgt cgcgatgatg gcggtttttg ctttaagtga
     6001 tataccgtta gctaagccaa tattaataaa atgttgctct ttatttaagg aaacggcctg
     6061 ttgattcatc ataatgtcga tagggtaact acgcacatga ctttctactt gctgcatcaa
     6121 ttttggacct tctgtgtaag aggtaccaat catattttca atccctagtg tttcaacgac
     6181 ttgtccgccg aaagaatcag cgacaagtcc tgtacggatt cctttacgtg ctgcatagat
     6241 agctgcacta ctagctgctg gtccaccgcc aattactaat acatcataag gttctttttc
     6301 aaacaactct tcttcaatca aagggccagt gattttttca acaatttgtt cgatcgtcat
     6361 gcgtccgcta ctaaattctt ctccatttaa aaacacagtt ggcactgcca tgattttttt
     6421 atcatcgatt tctttttgga acatcccacc ttcaatcatc gtatgagtaa tatttggatt
     6481 taatacagct aatatattca atgcctgtac aacgtcgggg caattatgac aagtcaagct
     6541 aacataactg tcaaaatgca atgtttgtgt tatttttttg attttaagac tcaaagattc
     6601 actgattttc ggtgcccgtc cactaatttg taacatagcc agtaaaaaag aggaaaattc
     6661 atgaccgagg gggataccag caaaaacgat tccactttct ttgccaactg gattgataga
     6721 aaaactaggt gtgcgcatcg aatctctttt ttcccaagag attttaggag acatttctgc
     6781 tatttccttc gtaaattcag ctagtttttg actattttca ctattatcca aactaacaga
     6841 aaaaacaata ggagattcaa tcagtgctaa atattgttcg agattttgtt tagtttcttt
     6901 gtctaacata tccaccacct aaatctttcc aacaagatca aaacttggtt tcaatgtttc
     6961 gccactttct ttccattttg ccggacaaac ttcacctggg tgggtacgta catattgagc
     7021 agcgcgaatc ttatcaatca gtgcactagc gtcacgaccg attccatctg cattgatttc
     7081 catagcttga acgattccgt ctggatcaat aataaatgtt cctcgctgag ctaatccttg
     7141 ctcttcatcc aaaacatcaa aaatacgaga aatctgatga gacggatcac cgatcatcac
     7201 gtattcgatt ttaccgatag catctgatgt atcatgccat gctttgtgag taaagtgggt
     7261 atcggtagag caagaaaaga cttcaacacc taaagatttc aatgtactgt attgttcttg
     7321 taagtcttct aattcagtag gacaaacaaa agtaaaatca gctggataga agcaaagaat
     7381 actccagttc cccataagat ctttttcact gacttctaaa aattctcctt gatgataagc
     7441 atgtgcatta aattcttcga tttttttccc aatcaatgac atagtaaaac ctccaataat
     7501 aattatttat ttataattat tgtaatttag ttggagttgc aaagtcaatg gatattttgt
     7561 tatttaataa agattactca aaaacgaagg ttaattataa aaatagaaga ggtcgcaaga
     7621 aaatgctact gctggaaata ctcgggataa cgttgagtaa cagtttcctg ttctttcagc
     7681 atcatgtgta agtgcaatcc cgtttgaaat cgagcttctt ctggtttttt atcaactaaa
     7741 gccttgagta aatcataatg ttgttccatg atcgtttccc atggaagccc ctgaatggtc
     7801 actcgtaacc agcggaaacg ttctaaatgg gtattatggt catctaacca gttccaaact
     7861 tcttttcttc ctgcaatttc gaaacaagct tcatgaaata aattatctgc acggaaaaaa
     7921 gcgcgttcgt catttatttt gactgctttt tcttgttctt ctaaaatcgt ttctagcact
     7981 attcgtgttt gtgtgtccaa tttggaacaa cattcaatca tgatttgctc ttccaactgt
     8041 tctcggacaa agcgagcatt ttctgcagaa acaagattaa ttttggaaac atacgtacca
     8101 ctttgaggta tcgtatacac gagttcttgc tgacgtagtt gaatcaatgc ttcgcgaatg
     8161 ggagtccggc cgatagcaag atgttcctcc agtgcctttt cagatatttt ccttccaggt
     8221 tctaagtcag catagataat ttgtttacga atcgcttgat aagcttgtga ttgcaagctg
     8281 cttttcatct ttattcctcc aaaatcattt ctatgaacgt agtataacag aagaggtctg
     8341 aaaaacaatc tggtatgtca cattaactag taaatttgta taaatagtaa aattttggtt
     8401 gacatagcga tttttattgt ataaaattca cttgaataca aaaactaata tgttagttta
     8461 ggaggggaaa aatgattgat ttaaacaact ggaggaactt tatccctgaa ttatctcaaa
     8521 aagaagtaga aatacctcat tttgaccgtg catcattaag agaaaatgga caaaaaaatc
     8581 ctgtctggat ccatttcggt ggcggaaatc tttatcgagg atttcatgca gaaatcgctc
     8641 aacgtttagc ggatctaggc gaattgtcca ctggtgtcat tgtttgtgaa acattcgatg
     8701 aagaaataat tgaaagggct taccaagatt ttgatgattt gattcttgaa gtggtcatgc
     8761 caagcagtgg agagttcgtc aaacgtatat tagctgcgac agctgacagt ctgtattgtc
     8821 atccagattg ttctgaacac tttgataaga tgattcgaca ctttgaaaat cctagtttac
     8881 aattagttac ttttgctatt actgaaaaag gttatcgatt gaaagataca aataataaat
     8941 atataggacc gattgcagtc gatataaaaa atggtccaaa gaagccatca catacaatga
     9001 gtattcttgc tgcgctactt tataaacgtt ttttatctgg agcttggccg attgcacttg
     9061 tctctacaga taatttttca caaaacggta gtcaattacg tacttctttg ctaacgatcg
     9121 caaaagaatg gcaaaaggaa ggttatgtac aaaatacatt tatccaatac ttatcgaatg
     9181 aagaaattgt tgcgtttcca tggacgatga ttgatcgtat caccccgaat ccttccttgt
     9241 cagttagcaa aatgttggca aaagagggct tttcaaatat gtcgattttc caaaccgcaa
     9301 aaggaaataa tattgctcca tttgtcaata cagaggacat ccattattta atcatggaag
     9361 atcattttcc caatggacgt ccgaaattcg aaaaagctgg ggtattcttg actgatcgtg
     9421 caacggtaga taaagcagat acgatgaagg tgacgacttg ccttaatcct ttgcatacgt
     9481 ctttagctat tatgggttgt ttactggggt ataggagcat agctgaggag atgaaagatc
     9541 cagatttatc gctgctagtt tctgaaatcg ggtacaatga aggcctccca gttgtggagt
     9601 ctccaggtat cattgatcca aagatctttc tggaagaagt aattactgtg cgcttttcta
     9661 atccaaatat tcctgatatg cctcagcgaa tcgccacgga tacctctcaa aaggtggcga
     9721 ttcgttatgg tgagacgatt aaaaaatata tggaaataga agttaaagac ccgcagacac
     9781 ttgtattcat accattgact ctcgctgctt ggcttcgata ccttattggc attgatgatc
     9841 aaggaaaacc attcatcccg agtccagacc cactattgac agactttcag cataagcttt
     9901 ccgatattca actgggtacg caagatacat cacatattca tgagaaaatg gctcctattt
     9961 tgtcaaataa agaaattttt ggtgtagatc tttaccaagc agagcttggc agaaaaatag
    10021 aagaaatgtt catcaagatg gtagcaggac cgaatgccgt acgaaaaaca ttacaggatt
    10081 acttacaaga acatggagga aatttatcat ggaaatgact tttagatggt acggatcaca
    10141 ggaagaaaag attaccttag atgaaatcag acagattcct gcggtcaaag ggattgtagg
    10201 cacattgatg gatataccag taggagaggt atggcccagg gagaggatca aagaactaaa
    10261 agaagaaatt gagtctcgtg ggttaacact aaaagtaatt gaaagcgtca atgtgcatga
    10321 tgccattaaa attggattac cttcccgtga gcagtatatc gaaaactata agcagacaat
    10381 ccgaaacttg gcagaatatg gaatagaagt catctgctat aattttatgc ctgtatttga
    10441 ctgggtgaaa tctgaccttg actaccgctt agaagacggc tcatccacgt tagcttttat
    10501 atctgatgat attccagatg atccaagaga aatcgtcgcg cgcatcgaac attccagcaa
    10561 tgaatttgaa ttgccgggat gggaacctga gcgcttagct catatcaaat ccttgcttga
    10621 agcctatgca tcagtagacg aagaaaaact tcgagaaaat tttgcctatt ttctccaatc
    10681 aatcatccca acatgtgaag aggtaggggt caaaatggct gtacatccag atgatccgcc
    10741 atactcgatt tttggattac ctcgaatcgt aaagaatcga gaagatttag attggttgtg
    10801 ccgcatagta gacagccctt ataacggaat cactctttgt acagggagta ttgcagaaga
    10861 tccagaaaat gatgtatatg ggattttagc agaattttgt caaagagatc gaatcccatt
    10921 tgcacatgtt cgaaatatta aatttttagc taatcgagat ttctatgagg caccgcataa
    10981 atccgaatac ggttcattag acatgtaccg catactaaaa acaatgtatg acaacggatt
    11041 taacgaatac atccgtcctg atcatggaag aatgatctgg aatgagacag gaagaccagg
    11101 atacggctta tatgatcgag cattaggtgc tgtttatcta aatggattat gggaagcaat
    11161 cgaaaaagga aacaaaagta aagataatta gtgaaaaaaa ctgtaatttt attatgtaaa
    11221 taagaaggat gttcaaattc ttgatacata aatccggagg ttgttaataa gcattcggat
    11281 ttatgtatct tatttggtct aggaagtaac ttgattttct tttttcgatt gatccatgag
    11341 tgcttcttct tttaattcaa agatatattc tgagatcctc ataatcactt ttttccagtc
    11401 ttctggtgtg atgattcctt ttaaaatata gatttttttg atatgagaag gcaattgttt
    11461 caaagggcag tcgctgataa cgatgttgca gttctccata aaatcatttt gtattttgat
    11521 cgattcattt gaaaaaattt gttctatctt aacgatcaga tctttactga tataaaaatc
    11581 acgcgtatag ttcacaccaa tcacaattcg cggctgtttt ttgtagcgat catacaaatg
    11641 tactaggtct tcaaccatcc attgcacatt ttccttttct aaaataactg gtaacaagtg
    11701 ttgattttgt tctctgaaat ccatataaaa ttgttcaatg gcggtttgga cttctttcaa
    11761 cacgctatgt tcttgataaa gcatgaaagt aggaaggggc gtatttggtt gattgaagtt
    11821 aagaaatcca ttataaagtt tatttcgtgc gaatgccaat gagtaaagaa tcttttcttt
    11881 ttcaggtata aacaaatcaa atacagtaca aaaggactcc accatttctc ttgaataaag
    11941 aacatgagga acgtttgctt tttttaaaag tttgtattgc tccaagcttg tttcttccga
    12001 ttcgattttc gtgatagaaa gtcgagctaa aatattcact aagatgcgtt gttcgcgaca
    12061 aattggcaga ttaggtcgca aaatatctac agagggatca ataaaaaagt caatatattc
    12121 atactctgtg aattcttttt gtacgtcttt cacagaagtt gcaggaaaat tctctttaca
    12181 tatttttaat agaaaatata atttatctat cataccgcta tttagtcggt caagtacttc
    12241 ttttttaaaa aaagtattca tcataaaagc cactacttgc ggatcttcat cataaaattc
    12301 tgtagcagta cttgaaaaga tgttccaata aatatctaat gctgcatatt gaatttgtac
    12361 ctcttttcca gaaaaagact ttctgccatt attagaaaag gagatagaca aaccgtacaa
    12421 tgctaaaaat gcattaatct ttttcatttt cgtatacaaa taagaggcac tatagtttgt
    12481 ttgctgactt aaactgataa tcgaatttgt ctgacagctg aacaaagaag tcaagatctg
    12541 ataactgact gattcgttgc agtatcttcc aaatagacga taatagcagt aagccggatc
    12601 aattccttca aaattcaact ttaaaaaagg tttttgctta tcaatatgca gttctgttag
    12661 attgagacgc tcaaagtctt gttctaattc tttgatgtat agtaaaaaat ttgattcaga
    12721 catatggaaa tgatctgcta aatattgtgt agtaataaag aaacgatgtt cagataggaa
    12781 aagaaaaata tctaattttg tattgctttt tttcttcaag agaaacgttt taatcgcttc
    12841 ttgagtttgc atgaaagagg ctccttttta cttaa
//
LOCUS       DACDAF010000075        12859 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.076, whole genome shotgun sequence.
ACCESSION   DACDAF010000075 DACDAF010000000
VERSION     DACDAF010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12859
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.076"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            134..3661
                     /locus_tag="IVZ69_002072"
     CDS             134..3661
                     /locus_tag="IVZ69_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HAP8184144.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3658..7380
                     /gene="addA"
                     /locus_tag="IVZ69_002073"
     CDS             3658..7380
                     /gene="addA"
                     /locus_tag="IVZ69_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HAP8184145.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7449..7790
                     /locus_tag="IVZ69_002074"
     CDS             7449..7790
                     /locus_tag="IVZ69_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184146.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8099..9142
                     /gene="pheS"
                     /locus_tag="IVZ69_002075"
     CDS             8099..9142
                     /gene="pheS"
                     /locus_tag="IVZ69_002075"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HAP8184147.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9147..11567
                     /locus_tag="IVZ69_002076"
     CDS             9147..11567
                     /locus_tag="IVZ69_002076"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HAP8184148.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="IVZ69_002077"
     CDS             complement(11737..12747)
                     /gene="trpS"
                     /locus_tag="IVZ69_002077"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HAP8184149.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
BASE COUNT         4360 a         2240 c         2728 g         3531 t
ORIGIN      
        1 ttttttgcgt atacttaaaa aagtagaaat atcagaacct taaaaggata taatttgaag
       61 aatatagaac aaatgttcag tattttttga tataataaag gagcaccgta tcatgtgttg
      121 aaggaggaaa agcatgtctt tacaatttat tcttggaaac gggaaaaaag atcaccgtca
      181 agtcttgatc gacgaagcat ccgcttggct cgaccaggat gcaagtaacc aagtattttt
      241 ccttgttccc aactacagca aattcgaaca ggaacaagaa attttagcgg agatgcgaag
      301 aagaagcgga aaaaaaactt tcagcacaac aaacgttcaa gtatttagtt tttatcgtct
      361 ggcttggtat ttgctgcaac agacaactct tcttacagga aatgaattat cagaatcagg
      421 atctgcaatg atcttgcgac agattttaga aaaaaatgag gaagaattaa caatctttcg
      481 cggagaaatc aataaaagag ggtttattcg tcaattacaa gaactctaca gtgaattgcg
      541 tacaggaaat attcaaccag aagacctgat gcttttattt ggtgattcac ctaatgcaga
      601 agaccagcaa cttaaaatga aagacttgaa gctgattttt tcagcttatg acagcgaatt
      661 gactcaacgt gcactaacaa atgaagatgc actatctata ctagcaaatt atatgcagac
      721 acaagatttc aacaacgtca aatttattgt cagtggtttt tctcgaatca atggtcaaga
      781 gtatcaatta ctgcaggcaa tgatggaaaa ggggcaattg gttgtcgatt tattgctgga
      841 tcgtccttat acagcggatc ttccagaagt acttacgctc tttcatgaga ctggaaagct
      901 ttatttccgt ctttttcaaa gtgcaagaga acggaaagtc cctatattag tggaccgatt
      961 tgcaccagag cagactcgtc cgacagagct tcaactgctg caaacaatgt gggaagagac
     1021 atctagccaa aagaaagcgg cagtacacaa aataggggga caagagcatc tccatttgtg
     1081 ggaagctgaa aatccaactg aagaagtccg acaattagct gttgaaatca gacgactagt
     1141 cagtgaagaa aactaccgtt atcgtgatat ccaagtgctg acaaaaaata tgtctttata
     1201 tggaaatatc cttcggccga tctttcaaga aatggcaatt cctttttata tcgatgaaga
     1261 acaaatgatg gaaaatcatc cgctgatcga atggatcaac agtctgttcg ctcttgaccg
     1321 ctattcttat cggctaagtg atattatgcg ttttttcaaa actgaattat ttctgtcgac
     1381 ggaagcagaa accgaacttg atgaatggaa acaagagcga gatgaattca ggaaaaaact
     1441 ggacatcact gaaaatgtag cacttgctta caattatcaa ggaacttatt ggactcgtga
     1501 aaaagactgg cagtttgtgg cgtatgattt tgaagcagaa cagattgaag acgtacagta
     1561 tttggaagaa cagtcaaata cgattagacg attatttcag aaagctgtac cagtattttt
     1621 gaaaaaaata aagaaaagca aaacaggaca agaggccgca aatgtttttt atcaattttt
     1681 gatccaaagt ggcgtacagc aacaattatt gttttggcgt aatcaggaag tagacagagg
     1741 aaacttagaa gcggcaagaa accatgagca gacatgggga gcgctgattg atctgttgga
     1801 tgaatatgta gtaatttatg gtgaatcggc ttttgactgg tcactgttcc aagaaatcat
     1861 tacaagtggt ctagaaaatc taagttatgg taaaatccct accgcaatcg accaagtgcg
     1921 aatcaatcgt ttggaattag ttcgaccaaa tcaagctgcc gtcacttttg cattagggtt
     1981 gaatgatcaa gtgtttccag accgaaaaga gacaaaagga ttgttgtcca gtgaagaacg
     2041 agaagtatta aatcaggcct tgccagatgg acagttttta ttcgacccat caaaggaaag
     2101 tatctctttt gagcctttcc aagcctatct tgtttttctt tccggaacag atcgattata
     2161 tcttagttat gcacaaagct atgacacaga tggttcgctg aagatgtctc cttatttgcg
     2221 tagaatcaca gaatatttat ctgttcccgt cgagagaaaa gagcatttga cgatcgaaag
     2281 cgaccctaat tgttatgtag ggacttacag aagcggaatc aatacagtca ataggattta
     2341 tcgattagct ttagatgaaa aaaaacctgt accaaagcac tggcaaaagc tcaaagaatt
     2401 agtactgaat tcgtcatggc gaaattttgc tttacagatt tttgaaagtc aggaacattt
     2461 aaatgttcct gtttcgatgc cagaaaaaat ggcggaagag ctttatggaa aagagattta
     2521 tacttcaatt tcacgtatgg agaattttta taattgtgaa tacaaatact tcatgcaatt
     2581 tggtttgaaa ttgaaagaac gaactgttta tggtctaact ccagcagcaa ctggtgattt
     2641 ttatcatgaa tcattggatc gtttcttcaa gctactgttt tcaaaccaat tatccttagt
     2701 gaatatgtcc gatgcgcagc gtagagactt tactgaaaaa gtgctgcagg aagtattcgg
     2761 agaacttcgg tttgagatat tggatagttc tgcaagaatg aactatatcc gctaccagtt
     2821 aggacagacg attcaaaaag tgacatgggc tttgcaaaaa cagagcaaaa atacaggcat
     2881 gcatcctctt cagacagaga ttctatttgg tcagattgct ggagcaaaag gtatcacagg
     2941 tctggaatta ccgttgagta atggtggaaa actccatgtt cgagggaaaa tcgatcgaat
     3001 cgatgtagct tctgaacaag aagatacttg gctaagcgtc gttgattaca aatctagcgg
     3061 acgttcattc gatgtcacag aagcttatta tggcatggct atgcaattat tgacgtatct
     3121 ggacgtagca ttgatggatg cggtacgttt gactggaaag gcggctgtta aaccagcagg
     3181 atcatattat ttacatgttc ataatcctgt attgacggag acagatgatg tagagaagaa
     3241 tacattgaaa aaatttagtt atgatggcgt ttttgtcgat gatcccgctc ttttagaagt
     3301 actagatcat tcactggaag caaaagaaca atcactgatc tatccagtga aaaaaaatgc
     3361 gaaagatgaa taccaaaaag gtagtttcag taaagacaaa tttttcacgg aagaagaact
     3421 gcaactattc atggcgcata atcgggaaaa tatgcggtta gctggagatg cgattacttc
     3481 cggagaaatc aaactaaatc cagcttataa agataaacag cggattgcct gcgaattttg
     3541 tccattcaga agcatctgta cgtttgatgt gatgctgaaa gaaaataatt accaccgtct
     3601 ggagaaaata gataaggaag aagcactgcg tagaatattg aaaaggagtg aagaagagtg
     3661 aatcaaattc ctttaaaacc gcaaaatgaa cgattcacag atgatcagtg gcaagcgatt
     3721 tttgatcaag gagataatct attagtctct gcgtctgccg gatcaggtaa aactacagtg
     3781 cttgttcgaa gagtgattga aaaactaaaa atgggttttg atatcgatga attattgatt
     3841 gtgacattta ctgaagctgc cgcaagagaa atgaaagaaa gaattcaaga ggcattacaa
     3901 gaatccgtca atagcgaaag tgaccctgta cgtagacagc attttactaa gcagttagtt
     3961 ttattgccca cagcgaatat ctcaacctta catgcttttt gcctgacagt tattcgacgt
     4021 tattattact taattgatat tgatccagtc tttcgcatgt taacagatga aacagaaacg
     4081 atcttgatga aggaggatgt gtgggacgag ctgagagaag cactttatgc agaaaatgat
     4141 gaacgatttt tccaattaac aatgaatttt tctaatgatc gttcagatga cggcttgacg
     4201 aatctggtgt tttctcttta tgagtttgcc cgtgccaacc ctgaccccca aaaatggcta
     4261 gaacagttaa gcgataatta tcgtttgcct gaggggctag cgaaatctcg attatatcaa
     4321 aaacaaatcc gtcctttagt tttggcagat atataccaat gtgtacagtt atatgaacag
     4381 atgactcagt tagcacaagg tgaaggatta gaaaaaatgc atgagcaagt agctggagaa
     4441 caacagcaga tcaagaatat ctatgaagcg ttctcgcaag atcggttaga agaagcttat
     4501 gctggtttgg aacaactaac tttttcaact tttaagagca gtcggaaagc agaattgaaa
     4561 gaaatttcca atgaagtcaa gggcatgagg gataaagcaa aaaaactgat tcagcagata
     4621 agtaaaagtt attttcctgt ttccccaagc caaatggaag aattaacgga caaagcacta
     4681 ccgttagtcg aagaaatgac aaaagtcacg caaagcttca tggacggttt cagtatgcgt
     4741 aaacgggaaa aaggtgtgct ggatttcaat gatctggaac atttagcgtt gcagattctc
     4801 acagaaaaaa cgaaagatgt atggctgcca agtgaagctt caaaacatta tcgaaaaaaa
     4861 ttcaaagaag taatggtaga tgaatatcaa gacgtgaacc aattacaaga agccatttta
     4921 tactggctaa gagaacccga tgatacaaaa ggaaatatgt tcatggttgg ggatgtcaaa
     4981 caatccatct attctttccg tttagcagat cctagtttat ttatcgggaa atacgagaat
     5041 ttctcaaaga aagaaggcgg acgtcgaatc gttttggctg agaacttccg ctctagaaaa
     5101 gaagtccttt cttttacgaa tcttattttt gaacaactaa tggatccagc agtgggtcaa
     5161 atcaattatg acgaagcagc caaactgatc caaggatttt cagactttcc agagaatgaa
     5221 cagtttgagc cggaaatcat gatctatgaa aaagaacagg aagaatcaga gattgagatt
     5281 ccgacggatg atatactgga agacaaaaca gaaggcgaac tttttatgac aggactaaaa
     5341 attcgtcaat taattgattc ctcctttatg atttatgata aaaaatcaaa aaaaagtcgt
     5401 ccgatagagt acaaagacat tgttctcttg acacctacaa agaagaacaa cttaacgatt
     5461 ttagagattt tcaaaacatt ggatattcca ttagagatga atgatgctca aaactatttt
     5521 caagcgacag aaattcgcac gatgatctcg ctgctacaat taatcgataa tccctatcaa
     5581 gatattccgc ttgcggctgt attgcgctca ccgatcgtgg gtctgattga accagaatta
     5641 gccagcattc gattagctaa ccgtgcacat acttactatg atgctgtgct tgcttatcaa
     5701 gcatcaaacg aagatgaatt agcagctaag ctggaacatt ttggcaagca actagagcat
     5761 tggcgagaac ttgctcgccg ttcttcgatc actgacttgt tatgggatat ctattatgag
     5821 acgggatatc tagagtatgt ggtcggtctg ccagcagggg cacagagaca agccaatctt
     5881 tatgcattgg ttgatcgtgc caaagcttac gagcaaagtt ctttcagagg attataccag
     5941 ttcgtgcgtt tcattgaaaa aatgcaagaa aaagataaag acttagcaga accagtcatt
     6001 tcaatagaag ataatgctgt tcgcgttatg acgatccatg caagtaaagg cttggaattc
     6061 ccagttgtat ttttgttaga tatgacaaag gagttcaact tacaagactt gcgcaatcgg
     6121 tatgcttttg aagaaaaact tggagcagga attcgctata tggatcctga aacacgagtg
     6181 ttatatgata cgttaccgtt tcaagccatc aaattggcaa agcaaaacaa attgttgtcg
     6241 gaagaaatgc gtaaattgta tgtaggattg actcgggcag aacaaaagct tttcattgtc
     6301 ggttcctata aaaataaaga gcaaatgatc caaacgtggt ctgaagcagc tgatcatgag
     6361 gagttagttt ttgatcctgc gctacgtttg aagggcagaa gcagcttgat gaattggatt
     6421 ggttacggat tgatccgtca tcctgaaatg cagaaatact tagaggaaga aatttcgact
     6481 tctcttcttc aacattcaaa tgcacagttt tctatttcat ggatgaatca gcaatcgatc
     6541 attgaacaaa gacagttgct tgctgaaaaa gaactggtta acttagatca gcagatgaaa
     6601 gaagatgaaa ctttattagc agattcgtta caaaaacgtc tggcatatga atatccttat
     6661 caagcttctt cacaaaccac aagttatcaa tctgtatctg aaatcaaacg attattcgaa
     6721 gatccagatg atacacaaga atcacgtttg actctggaaa gcagtcagaa caaagcagca
     6781 tcccgtcaat ttcgttatac gcaagaacaa ctagcagaac caaaattttt gcaaaaagat
     6841 cggcaagtgt cagcagctgc tgttggaact gctacgcatg ctttgttaca attactgcca
     6901 ttagagatgc caactacaga gagtatccat caaaaattac aggaattggt aaggaaacgg
     6961 ttagtagacg aaaaagtcgc gaaaaaagta gatgtttctt ctattatatg gttctttcaa
     7021 acagaacttg gtcaacagct gattgccaac aaagaaaacg taaaacgaga acaacctttt
     7081 tccatgctgc ttcctgctga cgaagtattt caagactatc caaatcaaga agatgaacta
     7141 ttaatccacg gaatcgtcga tggataccta gaagaaaaag atcatctcaa tatctatgat
     7201 tttaaaacag attttatttt acatccggat gatccagcag aaatagatgc aatcgtccaa
     7261 aaatatcaag gacagctaag actttaccaa caagcaatgt cagaagcttt gaataagcca
     7321 gtagaaaatg ttttcctaat tttgcttcga gtgaaacaaa ttataaacat taacaaataa
     7381 ttataattga gcaaacttga cttatgtttt gtaaggatta tgctatactc tgggaagagg
     7441 tgagtatgat ggagctaaca cagacagaat tcgttttatg ccctaaattt gaaaaaacat
     7501 tctctatttt aggaaaaaaa tggaacggat tgattatcga tgtactactc gaaaacggtc
     7561 cgcaacgctt tgttgagctt gcggcaaaaa tcccgatggt cagtgatcga gtattagtcg
     7621 aacgcttgaa ggaattagaa aaagaaggaa tagtcactcg aaactttgcc tgtagcgaaa
     7681 agagccgttc agaatatctc ttgactgaaa aaggagcaga cttgcaaaaa gcgatgcgtc
     7741 aaatacaagt ttggagcgaa aaatggatca cagaggaaga atgcggttga ttttgtaaaa
     7801 aaaatcttgt aaactatagt ccatacgaat aagtaaagaa cgatgacgaa aaagagtagt
     7861 ttggctaaac cagttcaggg agatctgtcg cagactgaaa gcagatcctg tgtttgaaaa
     7921 atgaagttca ctttccgagt tcgtctgata aaatcagacc ggcaattgtc gttaacgaag
     7981 taagagtgcg gtgtaagtca tttatccgca aattaggatg gtaacgcgaa gacctcgttc
     8041 cttaacagga atgaggtctt tttgttttgt atttggaatt taaaggagga acaagcacat
     8101 gtctctacaa gcacaattag agagcttgaa agaagcaacg ctcgtcaaaa tcacagcggc
     8161 acaagattta aatgaattaa atcaaatacg tgttgaaacg ttaggaaaaa aaggaccgat
     8221 cacagaagta ttacgtggga tgaaagatct aagtccagaa gagcgaccaa aagtcggaag
     8281 tttcgcaaat gagatccgag atcttttgac agaagagatc gagcgaaaaa aacaagtatt
     8341 agaagaagaa gcgttaaatg cagctttggc aaaagaaaca atagacgtga cactacctgg
     8401 tagaaaagta aaacatggta cacgtcatat cgtgacacaa atcatggaag aaattgaaga
     8461 tatttttgtg ggtatgggct atcagatcgt agaaggatat gaagtagaat ctgatcatta
     8521 caatttcgaa cggatgaatc tgccaaaaga tcatccagca agggacatgc aagatacttt
     8581 ctatatttca gacgagatat tgattcggac acatacttca ccagtccaag cacggacaat
     8641 ggaaaaacat gatttctcta agggtgctct acgaatgatc tcgccaggga aagtcttccg
     8701 cagagataca gatgatgcga cccacagtca tcagttccat caaattgaag ggctagttgt
     8761 tgataaaaac atcacaatgg gcgaccttaa aggaacatta gaagtcgtaa tgaaaaaaat
     8821 gtttggggaa gatcgtgaaa ttcgtttgcg tccaagttat ttcccattta cggaaccatc
     8881 agtagaagta gatgtcagct gtttcaaatg tggtggtgcc ggttgtaacg tatgtaaata
     8941 cactggatgg atcgaaattt taggagctgg catggtacac ccgaatgtgt tgaagatgtc
     9001 aggaatcgat ccagaagaat attcaggctt tgctttcggc cttggaccag accgcgtagc
     9061 tatgttgcgg tatggagtga atgatatccg taatttctat caaaatgact tacgtttctt
     9121 aagtcagttc aagggggagt aagaaaatgt tagtttcata taaatggctc aatcgttatg
     9181 tagatttatc gaatgtaaca ccaaaagaat tagcggataa gatgtctgtg acaggaatcg
     9241 aagtagaggg agtaacggtt ccagaagaag gcttgaaaaa aatcgttgtc ggtgaagtca
     9301 aggaatgcgt accacatcca gattctgatc acctttctat ttgtcaagtc gatattggcg
     9361 aagacgaact gtctcaaatc gtttgtggag cgcctaatgt gaaggttgga atcaaagtga
     9421 ttgttgcact tcctaactca cgtatcgctg gtaatgtaaa aatcaaaaaa ggaaaaatgc
     9481 gtggccaagt atcaaatggc atgatttgct cattacaaga aattggctat tcagatagtg
     9541 ttataccgaa agaatacgct gaaggtatct attatatgcc acaagaagct gtaaatggcg
     9601 atccagtttt tccttatttg gatatggatg attcgattat tgaattatct atcacaccga
     9661 atcgtgcgga tgcattgtca atgcgtggcg tagcttatga agttggggca atttatcgtc
     9721 agactcctac attcgatgac gaaaagctgg tagaatcctc acgtcctgct agcgataaaa
     9781 ttcaagtgga agttgaagat aaagaagcag ttcctgctta tcaaatcaga atcattgaag
     9841 gagtaagaat ccagccaagt cctcaatggc tgcaaaatct tttgatgaac gaaggcattc
     9901 gtccaatcaa caatgtagta gatgtgacga actatatttt gcttttattc ggacaaccac
     9961 tacatgcatt tgactacgac aaattgaaat caaaagagat ctttgtccgc cgtgcaaaag
    10021 aaaatgaaac attagtaaca ctagatggag aatctcggga attgacaact gacaatctcg
    10081 tcattactaa cggcaaagaa ccagttgctt tagctggtgt catgggaggg ttagactcag
    10141 agatcacgaa tgaaacaaca acagttgcac tagaatctgc tttatttgat ccaatttcga
    10201 ttcgtcgtac agcaaaacaa tttaatttgc gtagtgaatc ctctgcacgt tttgaaaaag
    10261 gaatcaacca tgcgactgtt ggagaagcca gtgaggttgc tgcagcaatg atcgtttctc
    10321 ttgcgggtgg ggaagttcta caaggcgcgg tcaaaggctc agagatcaaa gcagaagacg
    10381 tatcagtgaa gatttcactt gaacgcatca atcaatattt aggaacatct cttgtcgtta
    10441 aagaagtaaa tgagattttt gaagcacttg gatttagcta tgaagaaaag gagtatgttt
    10501 attccgtagt agtaccacca agacgctggg atatccaaat cgaagcagat attatcgaag
    10561 aagttgctcg tatttatgga tacgaccagt tgccatctac acttccaagt ggagaaacgg
    10621 ttgctggaag cttgtcaaaa gaacaagaaa ctactcgtaa aattcgtaca atctttgaag
    10681 gaagcggatt gagcgaagca atcagttatg cattgacaac agaagaaaaa tcaagacagt
    10741 ttgttataaa tgaaagtaat attacacgtt tggactggcc aatgagcgaa gaacgttctg
    10801 tattacgaat gaatttgatc agcggactat tagatgatat cagttataac actgcccgaa
    10861 aaaatacaga gattgcttta tatgaaattg gtcgggtgtt cttccaagaa aatgatccac
    10921 gtacacatct gccgcaagaa gtaaaacatg cagcaatcgc tatttctggt atttgggaag
    10981 aaaaagattg gcagacgaaa gctcaaaatg tagacttttt caccatcaag ggtcttttag
    11041 aaaacttatt tgaacaacta ggcatcactg aagatgtcca ttatcaaaca gtgacagaaa
    11101 tgaaggaaat gcatcctgga agaactgctg cgatttacct tggcgaaaaa tttattggtt
    11161 ttgtcggtca agtgcatcca acgattacaa aaagttatga tattccagaa acatatgttg
    11221 ctgagtttga tttatctgct atagtggaag ctgctcaaaa agggatcgtt ttcgaagcag
    11281 tgacaaaatt cccagcagtc agccgggaca tcgctttgct tgtaaaagaa actgtgacaa
    11341 atcaggaatt aacagaagtt atccgttctg ctgccggaag atttttaaca gatatccaat
    11401 tatttgatgt ctatcaagga gaaaacattg aaaaaggaca taaatccatg gcgtatagcc
    11461 tgacattcgt caacccagaa gcaacattga cagatgaaga aatcaataaa gcaatggaaa
    11521 aagtcgaaaa agcgttggta gaaaacctag aggcaagtat tcgctaagaa ggaaaatata
    11581 gtaagtaacg atcaagtagc ttttgaagac catacatttg aaaaaaagat gtgacacaac
    11641 ttcgtcacat ctcttttttt gattttaaaa aaggaatagc acagagacga gataaaaaaa
    11701 caggccttta cagcctgctt ttttagagta aatgaattaa tggaagtaat tgattcccat
    11761 tgctgatttt acttcagaaa gtgtttgtgc agctacttta gcagcttctt cactaccttt
    11821 acgtaagatt tccataacag ctgaaggatc tttttccaat tcttctcggc gcgcacggat
    11881 cggtgcaaat tcagcttcca atacatcaat gaggtatcgt ttgatcttta catcaccaag
    11941 tccgccgcgg cggtaatgag ctttcatttc ttcaattgct tctttatctg ttccgaatac
    12001 atccaagtag gtgaagacca tattcccttc tacttgtcca ggatcttgta catggatgtg
    12061 gtttggatca gtatacatac tcatgacttt tttctgtaag acatcggcag gatcggagat
    12121 ataaataccg tttcctaacg atttactcat tttgccattt ccatcgattc caggtaatct
    12181 acccattcct tttggtggga atacgccttt tggttccacc aagacttcac catatgtatg
    12241 attgaagctt tgtacgattt cctgtgtctg ctctagcatt ggtttttgat cctcaccaac
    12301 aggtacaaga ttcgctttga atgcagtgat atctgctgct tgagaaacag gatagataaa
    12361 gaatcctgta ggcacgcttt caccgaattt tttttgttcg atttctgttt tgacagtcgg
    12421 attgcgccga acgcgtccta cgctgactaa gttcaaataa tacatggtta attcagctaa
    12481 ttccggaatt tgtgattgga taaataaagt agattttgca ggatctaatc ccacggctaa
    12541 atagtctaaa gcaacttgca agacatttga tgaaaccttc tcaggatttt tagcattatc
    12601 tgtcagtgct tgcatgtcag caatcatgac aaacagttgg ttgtcttcat ctgcctgcat
    12661 agccactcgg gtttttagag aaccgacgta atgccctaaa tgcagcttcc cagttggtcg
    12721 atctcccgtt aaaataatat ttttcaaaaa agacacctct ttacgatttg taagtctgag
    12781 cacttaatat cttaccgttt ttcctgaaaa gaaacaacag ttcctaagga aaaaacaagg
    12841 aaagaggata aaataacta
//
LOCUS       DACDAF010000076        12594 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.077, whole genome shotgun sequence.
ACCESSION   DACDAF010000076 DACDAF010000000
VERSION     DACDAF010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.077"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            427..1248
                     /locus_tag="IVZ69_002078"
     CDS             427..1248
                     /locus_tag="IVZ69_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP8184150.1"
                     /translation="MYQFLKTGATILNYYQQYKENKKRCGRRSIALPEEQKEYVQKRV
                     VQGWTPDVIVGRSEMKLDCSVRTLYRMFQTGAFNVRDLPMKGKRKPNGHQEKRGKQAF
                     RRSIHERIKEHPEFENEFGHLEGDTIVGRKHKSAVITLVERLSKVIITLKPAGRQAMD
                     IENRINHWFQTVPKHLFKSITFDCGKEFSNWKAMGNQNDIDIYFADPGTPSQRALNEH
                     SNGLLRRDGLVKAMDFNEVSESFIEYRKHFLYSILSSFKFSIDYIYCEFCRGSET"
     gene            1335..1940
                     /locus_tag="IVZ69_002079"
     CDS             1335..1940
                     /locus_tag="IVZ69_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HAP8184151.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
     gene            1956..2528
                     /locus_tag="IVZ69_002080"
     CDS             1956..2528
                     /locus_tag="IVZ69_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8184152.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(2780..3037)
                     /locus_tag="IVZ69_002081"
     CDS             complement(2780..3037)
                     /locus_tag="IVZ69_002081"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184153.1"
                     /translation="MANLYIENKGDLNAIITLIVVMVKSIGNITIGMLFIILAAVLIF
                     MIVIWFLNERSKDNQHRRDMEIKSIESIDYLSIITLKKPRS"
     gene            complement(3163..3978)
                     /locus_tag="IVZ69_002082"
     CDS             complement(3163..3978)
                     /locus_tag="IVZ69_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184154.1"
                     /translation="MVKIAGLSKGGKTVSQLYKQNYRDWRQFRKNIKDSYFILPTELE
                     KYLPNNKAINLYLYYCFKAKNEGGDSWHSVNTIAESLGVTTKTINTWNKTLVDLGMIA
                     RIDDNHLSKSTILLPLSSYYKLALDSSLKDVTESTVHEIDGNLVAVYHLFEWRKNEAD
                     ENYNVPYNTLCCVFKRKTQKDTIYKFILVQDEKISNFELSTPSSKIYDDAYRFECQDL
                     EALLSANNLNNIEHENFVVNTRFNLVSEKDSDLLDLLIELTKNLDKKENITVL"
     gene            4495..5820
                     /locus_tag="IVZ69_002083"
     CDS             4495..5820
                     /locus_tag="IVZ69_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HAP8184155.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPAAKKKYGISNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSMNLFTTEGTRSQRRKKLAQMIQENIKEELGLLA
                     TVGVGDNPLLAKLALDNEAKHNDGFLAEWTYQNVPDKVWNIPEMTDLWGIGSRMKKRL
                     NQIGIMSIKDLANWNPYTIKSHLGVIGLQLYFHANGIDRTDIAIPPEPTKEKSYGNSQ
                     VLPRDYTRRNEIELVVKEMAEQVAIRIRQHNCKTGCVHLYIGTSILETRPGFSHQMKI
                     PITDNTKELQNYCLFLFDKYYEGQEVRHVGITYSKLVYTDSLQLDLFSDPQKQIDEEN
                     LDKIIDKIRQKYGFTSIVHASSMLEGARSITRSTLVGGHAGGAGGLKND"
     gene            5813..6163
                     /locus_tag="IVZ69_002084"
     CDS             5813..6163
                     /locus_tag="IVZ69_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184156.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEKIDADNEQRANQNLAKEQMTTE
                     EVAEVLNAAVIKNRSVCIQKEERNAEGYYPEDIVSKILGSDELGIYVGKNKVHYDEIR
                     HIEFYQDNKWGRLE"
     gene            complement(7234..7509)
                     /locus_tag="IVZ69_002085"
     CDS             complement(7234..7509)
                     /locus_tag="IVZ69_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgO"
                     /protein_id="HAP8184157.1"
                     /translation="MALLPTNKDKKKIGAEDISIKDDINVELGERKYTAKERKPVQVD
                     PPVLKTIRDLSYAKDIPMYEIVKLAMDAYVDTLNDEERIIYNRRSKD"
     gene            complement(7481..8434)
                     /locus_tag="IVZ69_002086"
     CDS             complement(7481..8434)
                     /locus_tag="IVZ69_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP8184158.1"
                     /translation="MENLRTAFKTSDKLGKVVMLTGRKGGIGKTTDNDLLAIVSSQLF
                     EKDVLLIDYDQQRNTTSNIGSTYQITSFDRSMSAAIKKGDWVSGITQVSPHLYIMAGS
                     PGSEELNEYLSEKYPDRRKRSLAFIKPLEELRKNFDYIFIDCPPSTDNVVRAFLTAAD
                     YIIAMQELKRYAMEGTEDFINKVLVPIVTNFEESHLQIIGILPVLFSVRRSSQHANYQ
                     KTIDKYGESNIFKSIVKGSDRLEMYGENGIQLNDYVDRRWWAIFADIFTELEERIEYY
                     EQHGDIEGFDYTPKYADSMANHILPLGKEIKLNGIITNEQR"
     gene            9046..10539
                     /locus_tag="IVZ69_002087"
     CDS             9046..10539
                     /locus_tag="IVZ69_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepR"
                     /protein_id="HAP8184159.1"
                     /translation="MLSEIYSAILKNGLRTYKYRNSTMKPAGHIDSSRSGAIFAYRSK
                     QLMNVGRGMVITSEEAILENEKKLTHWTPNTYRFGTYADDYRTVVKGHSEKNLSQINT
                     FVVDIDSKENHQGEIILACLDQVGYMPTLILESDHGYQVYFVLKTPGYVTKKSNFKVI
                     DVAKKISKTIRLQLAEKLSGVDLGCNHFGIARFPQENNIVFKEMNYQYSFADWIQWSM
                     KLESDQKTKEDRERKLIVFPEKKEIRQVDEPWFDMLLHKANIVGGEGRLGRNNVIFTL
                     SLAYYSSGYALDTCEYNMFTFNERLQEPLSEAELVKIVRSAYSGNYQAASREFIIELC
                     QQWVSPTLKNNDLFIQRRGWWKFKKPRDQRKYSHKNEWKEDLLAYLSEKSLASEPYLN
                     LSKKELASQLTMPKRTLDKILNELREENKVFYKVTRGRNGGMIIASVKTLFARVIQLS
                     KEKRLDYSTRITEVFGLNESLVEETFRQLSTPLNPLKEVNLFEVDTG"
     gene            10674..10970
                     /locus_tag="IVZ69_002088"
     CDS             10674..10970
                     /locus_tag="IVZ69_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system protein PrgN"
                     /protein_id="HAP8184160.1"
                     /translation="MSLKNYVYSHPVNVFIIGRLGLSVEVFCELYGFKQGTLSSWVTR
                     EKTVASLPIEFLHGLSLASGETMDQVYDCLCVLEQEYIEYKIANELRKRKKYIQ"
     gene            11071..11922
                     /locus_tag="IVZ69_002089"
     CDS             11071..11922
                     /locus_tag="IVZ69_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184161.1"
                     /translation="MKSDDWIEHTWLPLKRNSKRKKFWVLQLWPLGKLCSYGARLILD
                     LTVYSIGVFGTAYYLINDPNRIAASDIFTVLMTLIFVMLLSIFTQLVMQFTRQKLTAG
                     KLFKSLFDLIVVNAILATLIKQIEQSGRTTKGVKDFLLTFIHFVNGHMYLFEVGIILF
                     FVGYVSTKLIKRSIEKEIEIDLIPTLLGYEYNVDFGRYDELINTDIVHTSIHESTVKG
                     IRSILKNGQEMKAIDRRKEIYNFYEVEASLRYGIGKLWLDGSNIRQNKPYIFWNSSDL
                     ELPMKDK"
     gene            11943..12155
                     /locus_tag="IVZ69_002090"
     CDS             11943..12155
                     /locus_tag="IVZ69_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184162.1"
                     /translation="MIPLYRIVLIVGMELKTLKKEQLFKVKERHNQLLCSKTGTMNIE
                     YRTEYLELTNQTDFLLIRKQQEQEKN"
BASE COUNT         4354 a         1973 c         2322 g         3945 t
ORIGIN      
        1 aaataaagta gtaaattaat cataatcttt tcaacaacag gaatagtcaa gttagactgt
       61 tcctgttgtt tctttatttt ccttatcatc ttcaactttt tcaaatactg caaatacaaa
      121 atatcaatat aacttattcg ttctatcaat cagttcctaa tatctactca tcaaaatgaa
      181 atttcaaact aatctcatca tagtattctt ttcgtcgatt gtaaaattaa gctagacaac
      241 taaaaagatc atttgtgcta cactcaaaat agttccgacc aaagaattat taaggagtga
      301 gtacaaatga cctacaccca tcttacaaca gacgaactgg taatcataga gtcttatttc
      361 aaaaataatc aatccgttgc caaaactgcg caatgcttag gacgtgcgtg acaaacgatt
      421 cataacgtgt atcaattttt gaaaactggt gctacgatac tgaactacta tcaacaatac
      481 aaagaaaaca aaaaacgctg cggtagacgc tcgattgctt taccagagga acaaaaagaa
      541 tatgttcaaa agagggttgt tcaagggtgg acaccggatg tgattgtcgg ccgctcggaa
      601 atgaaacttg attgttcagt ccgtacactg tatcgaatgt ttcaaactgg cgcatttaat
      661 gtgcgtgatt tgcctatgaa aggcaaacga aaaccaaatg gacaccaaga aaaacgtggg
      721 aaacaagctt ttcggcgcag tatacatgag cgcatcaagg agcatccaga atttgaaaac
      781 gagtttggcc atcttgaagg agacactatt gtcggtcgaa aacacaaaag tgctgttatt
      841 acattggtgg aacgtttgtc aaaagtgatt attacattga agccagccgg tagacaggca
      901 atggacattg aaaatcgaat taatcattgg tttcaaacgg ttcctaaaca tctgtttaaa
      961 tcaattacgt ttgactgtgg gaaagaattt tcaaattgga aagctatggg aaatcaaaat
     1021 gatattgata tttattttgc ggatccaggc accccgtcac aacgcgctct aaatgaacat
     1081 tcaaatggat tattacgtcg tgatggatta gttaaagcca tggacttcaa tgaagtatca
     1141 gaatcattta tagagtacag aaaacatttt ctgtactcta ttttgtcttc ttttaaattt
     1201 tcaatagatt atatctattg tgaattttgt agagggtcag aaacttaata gtttttgaca
     1261 cataaacaaa atcgcgatat aatggggttg agagtgtttc ataaacttat gtcataaagt
     1321 taaggagatt tcgcatgatt ttagagaata aattgggatt aaccaatcaa gttgagttgg
     1381 ctaaggttga agaaaaactc agtaaacaaa aagcgaaaga attgtacgat tgtggaaaaa
     1441 taaatgaaat cgaagttggt acatttaaag gtttatctga aattcatgaa tttctatttt
     1501 cggatattta cgattttgcc ggaaaaatcc gatcggtcaa tattgcaaaa ggaaattttc
     1561 gatttgcacc agttatgtat ttagaacatt cgttacagca tattgatcag atgccacaaa
     1621 cttcttttga agagattatc aagaaatatg tggagatgaa tatcgctcac ccatttcgag
     1681 aaggaaatgg ccgaagtact agaatttggc tggatctcat tttaaaggaa gaattgcaaa
     1741 aagttgtaga ttggaactta atcgataaag cagactatct ttctgcaatg gagcgaagtc
     1801 ccataaacga tttggaaata cgctatctaa tttccaatgc tctgactgat aaaattgacg
     1861 atcgcgagtt atatatgaaa ggaatcgatg tcagctattt ctatgaaggg tattctgagt
     1921 atacgataga tgatttgtaa aagtaggtgg accaaatgac gaaatatgga tatgcacgtg
     1981 tctcaaccgc ttctcaaagt acaaaagaac aaattcaaca gttgcttgag aacggcgtag
     2041 agaagaagaa tattttttca gaaaaattta cgggtacaaa acgggatcgg ccaaaattca
     2101 atcagctgtt ggctggtctg aagcctggag atgaaatagt tgttacgaag cttgatcgat
     2161 ttgctcgtaa cacgagagaa gcattagaga tcattgaacc tttactcgat gataacgtaa
     2221 cgatcaaggt tttgaatcta ggaacgattg aaaatacgtc catggggcga atggtgacac
     2281 ggacgttgtt gagtgtagca gaaatggaac gtgatatgat tgtggaacgt acccaagaag
     2341 gaaaaatgtt tgcaagaaag aataatccta atttcagaga aggacgtccg aaagcaacaa
     2401 tcacaccgaa gaagaggcac gcatatgaac tgcttacttc aggtaaatcg tataaggaag
     2461 ttgaagctat aaccggtttc agtcgcagta cgctttttag aataaagaag aaaattgaag
     2521 aaagttaaaa aagaagtctc agcgaaccag acaggtaaat acttaatgcg ttctagatat
     2581 gagtctatta gcatgttgtg aaatataata tttttttatt tacttgattt ctgctcaaaa
     2641 aatgtgtatg gtaactgtaa aaggtaaagt aattaaaggt atgctagcca cgcttactat
     2701 attaggatac catcatatat ttataatgaa cgatttgttc gtctaccaaa caacacatat
     2761 cgttcagcgt aagtcacgtt taggaacgtg gcttttttag tgttattatc gataaataat
     2821 ctattgactc tattgatttt atctccatat ccctacggtg ttgattgtct ttagatcttt
     2881 catttaagaa ccaaataact atcataaaaa tcagcactgc tgctaatata ataaacagca
     2941 ttcctattgt gatattacct attgatttta ccataactac gattaaagta ataatggcat
     3001 tcaagtctcc tttgttctct atatataaat tagccataaa tcatcttcct ttcaaattaa
     3061 gatacttgtt tgataccaat aaatagtaag cgtggctagc ataccttttt ctgtaatagc
     3121 aagtgttcta atagtccaaa cttaatgatg gaccgatgct agttatagta cagtaatgtt
     3181 ttctttctta tctagatttt tagtaagctc tatcagcaaa tctaacaaat ctgagtcctt
     3241 ttcagaaact aaattaaatc tagtgtttac aacaaagttt tcatgttcta tattgtttag
     3301 attatttgcg gaaaggaggg cttctagatc ttgacattca aatctatatg catcgtcata
     3361 aatcttacta gaaggagtgc ttaattcgaa attacttatt ttctcatctt ggaccaagat
     3421 aaatttatag atagtatctt tttgtgtttt tcttttaaaa acacaacaga gtgtgttata
     3481 aggaacgtta taattttcat cagcctcatt ttttctccat tcaaacaaat gataaactgc
     3541 aaccaagttg ccatcaattt catggacagt gctctcggta acatccttta aagaactatc
     3601 aagggctaat ttatagtaac tagagagagg aagtaaaatt gtcgatttac tgagatggtt
     3661 atcgtctata cgtgcaatca tacctaaatc aactaaggtt ttattccagg tgtttatagt
     3721 tttagttgtc actcctagag actctgctat ggtattgacc gaatgccagg aatccccgcc
     3781 ttcattcttt gccttaaaac agtaatacag atataaatta atagctttgt tattcggtaa
     3841 atatttttca agttctgttg gtagaataaa gtaagaatcc ttaatgtttt ttctgaactg
     3901 tctccagtct ctgtagtttt gtttataaag ttgtgaaacg gtttttccac ctttagaaag
     3961 tcctgctatc ttaaccaatc ttattgctcc tttcttgaat ctgtcatgat catacagtat
     4021 tttttacttg tagtccagca ccttaatata ttatcctatg taattaattt cgtactagat
     4081 agtaattatt ttttatttaa ttctctagtc acttacaaat aagttatata aactacgatt
     4141 aataaattat tacaaaaact attaagaaaa cttctacata caactattac aaaactatta
     4201 agaaactgaa tactcctatt ttttgttttt aaggaaagtt ttttcttttt tgaatttctt
     4261 atttttttct aatataacta agcaaaactg gataatacga cacttatttt caaattttca
     4321 caagactaat agtaaatatc catttaataa agtgatacaa tgtgttgatt ttacaaatca
     4381 acagaagaag tagggaaata acttacctat gcttcttttt ttgtacattt aatcgattct
     4441 tctttacaaa aacgaacgta tgtttgtata atgtggaaga atggagtgtt atttatgatg
     4501 gattattcaa aagagccagt aaatgattac tttttgatcg atatgaaaag cttttacgca
     4561 agtgtcgaat gtatagaaag gaatttagat ccattaacga ctgaattagt cgtcatgagt
     4621 cgagcggata atacaggatc agggttgatt ttagcttctt caccagctgc aaagaagaag
     4681 tacggtattt ctaatgtcag tcgaccacga gatctaccgc aaccttttcc taaaacgtta
     4741 catgtcgttc caccacgcat gaatctctat attaagcgaa atatgcaggt aaacaatatt
     4801 ttcagaaggt atgtagcaga cgaagattta ttgatttact cgatcgatga atcgatctta
     4861 aaagtgacca gatcaatgaa tctttttacg actgaaggaa caagaagtca acggagaaag
     4921 aagctggctc aaatgatcca ggagaatatt aaagaagagc taggattgct tgctacagta
     4981 ggtgtcggag ataatccctt attagctaaa cttgctttag acaatgaagc aaaacataat
     5041 gatggattcc ttgctgaatg gacgtatcaa aatgttcctg ataaagtatg gaatattcct
     5101 gaaatgacag acctttgggg tattggatct cgaatgaaaa aaagactcaa ccaaattggt
     5161 atcatgagta ttaaagactt agctaattgg aatccataca ctattaagag ccatttaggt
     5221 gtgattggct tacagctgta ttttcatgcg aacgggatcg atcgaacaga tatagcgatc
     5281 ccaccagaac cgacaaagga aaaatcatat ggtaattcac aagtgttacc acgagattat
     5341 accaggagaa atgaaatcga actggtggta aaagaaatgg cggaacaagt agctattcgt
     5401 atcaggcaac ataactgtaa aacaggttgt gtccatttat acattggcac gtcgatctta
     5461 gaaacgagac caggtttttc acaccagatg aagatcccta taacagataa tacaaaggaa
     5521 ttgcagaatt actgtctttt cttgtttgat aagtattatg aaggacaaga agtaaggcac
     5581 gttggaataa cctatagcaa gcttgtgtac actgattcgc ttcagctgga tttatttagt
     5641 gatccacaaa agcaaattga cgaagaaaat ttagataaaa ttattgacaa gattcggcaa
     5701 aaatatggtt ttacgtcgat tgtacatgct tcttctatgt tagaaggcgc tcgtagtatt
     5761 actagaagta cattggttgg tggccatgca ggcggcgcag gagggcttaa aaatgattga
     5821 ttataatgat cgtggacgtt taaagtgggc aggtttttat ttatctgatc atactgaaaa
     5881 aattgatgcc gacaatgaac aacgagccaa tcaaaatttg gcaaaagaac aaatgacgac
     5941 tgaagaggtt gcggaagtat tgaacgctgc agtcataaaa aatagatcag tatgtattca
     6001 aaaagaagaa cgaaacgctg aaggatacta tccagaagat attgttagca agatcttagg
     6061 tagtgatgag ctggggatct acgttggaaa aaacaaagtt cactacgacg aaatacgtca
     6121 tatcgaattt taccaggata ataaatgggg tcgattagaa tgaacattat ccagcaatat
     6181 gagctaaagt atataacctt tgatcagcta tcagaagaga tttggggtta tggccagcgt
     6241 ttgataaatg aggttggtgt tgaacgcttc tctttctatg tagaagctgc agcaggatac
     6301 cataaatacg aatactatat tggctattaa agtgcaataa aattatattt cttttatgtt
     6361 ttacattttg tatcaattct gataaaatta cctataggta attaaaaaat ataaaaaaac
     6421 tagttacaac cttaggacgt tgtaactagc ttgaagcata ctagagctaa ctaaaatagc
     6481 actagaaagc aatgttaaac ccgtccaaca aacttgattt aacattgaga ccagcttatt
     6541 cagctaaata tagttgaata agcttctttt gttttaaaaa aacaaaaggt gtactacgaa
     6601 taacgcaagt aaaagaaata ctattacaac cagtaggcta caagtaagta ttactaaaca
     6661 ttgcgtagtt agaacctttg ctctattgtc taaagccaca aaattagaga tcagctttat
     6721 gatgctaaga gcgagctgca tccatgcgga cataggttct tttgacacta ttaattctcc
     6781 tttttaggat aagggaaatt gctagtagtt ttttcattag caccatcccc cttcatttga
     6841 ttgagtctag tgctgctgtg atagtttgct gtttaatatg cttacattct tattataaca
     6901 taaatgaaac aaacacatgg ttagaggtcg tatcaatcaa aatagtgtct cacaaacgat
     6961 ttattactta ctcctgctga ctaacggact gttcttcagt aactgtaact atatgtttgt
     7021 taaaaccacc attacctgta gataaaaacc aatatattta ctatactcac tatattaaat
     7081 atatttagta tagtaaaaac tagaaacaat aaaatttgtg aatgttgtat acccccaaac
     7141 aatacacata ttttgaagga ttaggattaa taaagctaaa aatatagtaa gtatactaaa
     7201 tatatttact atatctagta tacttactat attttaatct tttgatcgtc tattatatat
     7261 aatccgttcc tcgtcgttta aagtatcaac ataggcgtcc attgcaagtt tgactatttc
     7321 atacatagga atatcttttg cataactaag atcccgaatg gtttttagta cgggaggatc
     7381 tacttgaact ggttttcttt ctttcgcagt gtactttcgt tcccctaact cgacattaat
     7441 atcatcttta attgaaatat cttcagcacc aattttcttc ttatctttgt tcgttggtaa
     7501 taatgccatt tagtttaatc tcctttccaa gaggtaggat atgattggcc attgagtcag
     7561 catatttagg tgtataatca aatccttcaa tatcaccatg ttgttcatag tattcaattc
     7621 tttcttctaa ttctgtaaag atgtctgcaa aaatagccca ccatcttcga tctacataat
     7681 catttaattg gataccattc tcaccataca tttctaaccg atccgagcct ttaacaatgc
     7741 ttttaaaaat gtttgattca ccatacttat caattgtttt ttgatagttt gcgtgttgag
     7801 aggaacgtcg cactgagaaa agaacaggca aaattccaat gatttgaaga tgagactctt
     7861 caaaattcgt gacaatcgga actaaaactt tattaataaa atcttctgtt ccttccattg
     7921 cgtaccgttt taattcttgc attgcaataa tataatctgc agcagttaag aatgcacgaa
     7981 ccacattatc tgttgatggt gggcagtcga taaagatata atcgaaattt tttctcaatt
     8041 cttctaaagg tttaatgaag gccaatgatc tcttacgacg atcaggatat ttttcggaca
     8101 agtattcatt aagttcttca gatccaggag agccagccat aatatataaa tgtggactta
     8161 cttgagtaat acctgaaacc cagtcccctt ttttgattgc tgcagacatg gatcgatcaa
     8221 agctagtaat ttgatacgtt gatccaatgt tggaagtagt atttctttgt tggtcataat
     8281 caattagcaa cacgtctttt tcaaaaagtt gactagaaac aatcgctaat aaatcattgt
     8341 ctgtagtctt accaatgccg ccttttctac ctgtaagcat tacaactttt cctagtttat
     8401 ctgatgtttt aaatgcagtc cgtaagtttt ccatagttcc ctccaatttc ctatactaaa
     8461 tatatttagt atacttcata tacttaatat attcgatata tctaatatac tccaaattga
     8521 taagaattca gactttataa ggaatatagt ggatatacta aatatatttg ctatattcag
     8581 tatatcagat atattcaaaa tgtcaaaata tatttgtgcg ttttgcgttg acaatttaga
     8641 gtgaaaagag gtaaacttaa ttctatagaa accacagata attcactatt tacaaagtag
     8701 caaaagcagt ggtactcttt aaacagaaaa attacataaa aaaaagagac ggaaataatt
     8761 gattttagca gaatcaatta tttctgaatc acatggttag gacatgtgtt cacgctcgtc
     8821 tcaagaatat gtaagtagct accaactact tatattaaaa gttgatcgga taccttttcc
     8881 gattgccttt attctaccaa aaaaaggcga gcaactcaac agaagaacgt ttatttagtg
     8941 tacttaaatt aaatattctt aaacactgaa gagagaacac atactatggc tgagattaaa
     9001 gctaaactgt gttctctttt tgtttgagaa aggacgttac aatcgatgtt gagcgaaatt
     9061 tattcagcta ttcttaaaaa cggcttacgt acatacaaat atcgaaacag caccatgaaa
     9121 cctgcaggtc atattgattc cagtaggagt ggtgctatct ttgcgtaccg tagcaagcaa
     9181 ttaatgaatg ttgggcgtgg tatggtcatt acttcggaag aagctatttt agagaacgaa
     9241 aagaaactaa cgcattggac acctaatacc tatcgctttg gtacttatgc ggatgattat
     9301 cgaacagtgg ttaaaggtca ttctgagaaa aacttaagtc aaatcaacac atttgtagtt
     9361 gatatcgatt caaaagagaa ccatcaaggc gaaattattt tagcctgttt agatcaagtg
     9421 ggctacatgc caacgctaat tttagaatca gatcatggtt atcaagttta ttttgtacta
     9481 aagacaccag gctatgtcac aaagaaaagc aatttcaagg tgatcgatgt agcaaaaaaa
     9541 atttcaaaaa caattcgtct acagttggct gaaaaattgt ccggagtgga tctaggatgt
     9601 aaccacttcg gaattgctcg attcccacaa gaaaataata ttgtttttaa agaaatgaac
     9661 tatcagtatt cttttgctga ctggattcaa tggtcgatga agcttgaatc agatcaaaaa
     9721 acaaaagaag atcgagaacg aaaactaatt gtctttcctg agaaaaaaga aattcgtcaa
     9781 gtagatgaac cgtggttcga tatgttactt cataaagcaa acatcgtcgg cggagaagga
     9841 cgtcttggtc gaaataatgt gattttcacg ctttctttag cttattactc ttcaggttat
     9901 gcattggata cttgcgaata caatatgttc acattcaacg aacggttaca ggaaccgcta
     9961 tctgaagcag aattagtaaa gattgtacgt agtgcttatt ctggtaatta tcaagcagca
    10021 agcagagaat tcattattga attgtgccag caatgggttt caccaacctt aaaaaataat
    10081 gatctgttca ttcaacgacg tggctggtgg aaatttaaaa agccacgaga tcaaagaaaa
    10141 tatagtcata aaaatgaatg gaaagaagat ctattggctt atctaagcga aaaaagtctt
    10201 gctagtgagc cttatttgaa cctgtcaaaa aaagaattgg cttcacaact aacgatgccc
    10261 aagcgaacac ttgataagat cttaaatgag ttacgagagg agaataaagt cttctacaag
    10321 gtaacacgag gaagaaatgg cggaatgatc attgcttcag tcaaaacgtt gttcgcgagg
    10381 gttattcaac taagtaaaga aaagagacta gattattcaa caaggatcac agaggtattt
    10441 ggactcaacg agagcttagt agaagagaca tttagacaat tatcaacccc cttgaaccct
    10501 cttaaagaag tgaatctttt tgaagtagat acaggttgaa aaataaaagg tgcaaattgc
    10561 cttatacaat atatctatga tacttctgta ggtgttgctc cctttgccta gctacgtgta
    10621 ggtggtatac ttataactgc gtatgcagtc ttatgtatca tggaggaagt tgtatgtcgt
    10681 taaaaaatta tgtctattca catcctgtta atgtgtttat cattggtcgt ttgggattat
    10741 ctgtggaagt gttctgtgag ctttatggtt ttaagcaggg gactttgtct tcttgggtta
    10801 ccagggaaaa aacagttgct tctttgccga ttgagtttct tcatgggttg tccttagctt
    10861 ctggggagac tatggatcag gtatatgatt gtttgtgtgt gttagagcag gagtatattg
    10921 agtataaaat agctaacgag ttaagaaaaa ggaagaagta tatccagtag tagtttttat
    10981 ttacttaaaa aattggttca ttgagcaacc tatcgctgct aaagtagcaa aggaaaacgt
    11041 taaaggaaag aatttaggga agaaatcgaa atgaaatcgg acgactggat tgaacacacc
    11101 tggcttcctc tgaaaagaaa tagcaaacga aagaaatttt gggtattgca attatggcca
    11161 ttaggaaaac tttgtagtta cggggcacga cttattcttg atttaaccgt ttactcgatt
    11221 ggagtatttg gaacggctta ttacttgata aatgatccca ataggattgc agcatcagac
    11281 atttttacag tgctaatgac gttgattttt gtcatgctat tgtctatttt tactcaatta
    11341 gtcatgcaat ttaccaggca aaaattaaca gcaggaaaac ttttcaaaag cctattcgat
    11401 ttaattgttg taaatgcaat tctagcgact ttaataaaac aaattgaaca atctggaaga
    11461 acaacaaaag gagtgaagga ttttttattg acgtttattc actttgtaaa tggacacatg
    11521 tatttgtttg aagtgggtat tattctcttt tttgtcgggt atgtatccac gaaacttatt
    11581 aaacgttcaa ttgaaaaaga aattgaaatt gacctgattc cgacacttct tggttatgag
    11641 tacaatgttg attttggaag atatgacgaa ttgatcaata cggatatcgt tcacacgagt
    11701 atccatgaat ctactgttaa gggcatcaga tctattttaa aaaatggcca ggaaatgaaa
    11761 gcaatagatc gaagaaaaga gatctacaat ttttatgaag tcgaagcaag cctacgatat
    11821 ggcatcggaa aattgtggtt agatggaagt aatattcgtc aaaacaaacc atacattttt
    11881 tggaacagta gtgatttaga acttccaatg aaagataaat aattatggag aatcgtttga
    11941 aaatgattcc tctatacagg attgtgctta tagttggcat ggagttaaaa accttaaaga
    12001 aggagcagtt attcaaagtg aaagaacgtc ataatcagtt actatgtagt aaaacgggta
    12061 cgatgaacat tgaataccga acagaatatt tagaattaac gaatcaaact gattttttgt
    12121 tgattcgaaa gcaacaagag caagaaaaaa attaatggct acttatagcc aattgattga
    12181 tgaatgggaa caattcaagg aatctaaaat tccagaacgt ctctaaaagc ctttatttgt
    12241 aaagagcata aggaaacgtg ggaacacttt ttaaaaaaag tgttccaata ggctgtgcct
    12301 attacgtttc tcaaaaataa atgtgggaac aaaatattta aaaataggat agtgaaagga
    12361 tagtgaagga tagtaaaagg agggtagtag gatagcaaaa aggataggct ccttttcgct
    12421 atccttttta aattggagga attaatatgg aagtaagaat aagaaatgtg gatgagaaaa
    12481 tcgtaagaga aattgatcga agatgtgacg aacggttctg ttgcaaagtt ttaaatctac
    12541 tatcaaataa ggtagaataa tagaaaaaga tagcaggagg aatgacgatg aatc
//
LOCUS       DACDAF010000077        12164 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.078, whole genome shotgun sequence.
ACCESSION   DACDAF010000077 DACDAF010000000
VERSION     DACDAF010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12164)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12164)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12164
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.078"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(59..1042)
                     /locus_tag="IVZ69_002091"
                     /pseudo
     CDS             complement(59..1042)
                     /locus_tag="IVZ69_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311512.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(1437..2279)
                     /locus_tag="IVZ69_002092"
     CDS             complement(1437..2279)
                     /locus_tag="IVZ69_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HAP8184163.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIGI
                     PYINNLGLPEQEVMKIGNKLNDSRVEKILTCHCTGSKAFNILKTQLGNKLEAIKTGQH
                     LEIS"
     gene            2604..3020
                     /locus_tag="IVZ69_002093"
     CDS             2604..3020
                     /locus_tag="IVZ69_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP8184164.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            3017..3487
                     /locus_tag="IVZ69_002094"
     CDS             3017..3487
                     /locus_tag="IVZ69_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8184165.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            3501..4274
                     /locus_tag="IVZ69_002095"
     CDS             3501..4274
                     /locus_tag="IVZ69_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8184166.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAASPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            4288..5100
                     /locus_tag="IVZ69_002096"
     CDS             4288..5100
                     /locus_tag="IVZ69_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP8184167.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            5154..6119
                     /locus_tag="IVZ69_002097"
     CDS             5154..6119
                     /locus_tag="IVZ69_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP8184168.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            6256..8979
                     /locus_tag="IVZ69_002098"
     CDS             6256..8979
                     /locus_tag="IVZ69_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8184169.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESQILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGGSIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            8992..9624
                     /locus_tag="IVZ69_002099"
     CDS             8992..9624
                     /locus_tag="IVZ69_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HAP8184170.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKALRKEVKPLLDFLKKRDIP
                     LALASSSPAVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTAALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            9829..10056
                     /locus_tag="IVZ69_002100"
     CDS             9829..10056
                     /locus_tag="IVZ69_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009320234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HAP8184171.1"
                     /translation="MLQQNQNTNSYQAAILTAVNLGGDTDTTAAVTGALAGILYGGEV
                     IPENWRKSLQNDQLLKTISQRFCDTVLSQRI"
     gene            10125..10391
                     /locus_tag="IVZ69_002101"
     CDS             10125..10391
                     /locus_tag="IVZ69_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP8184172.1"
                     /translation="MLVQMMNGGRIMSQSTITFRIPDDEKELVLEYAKAHNSSLTELY
                     RNAVLDKIEDEIDLRTLRSAIEVSKEKKESGISQEEMEKLLNEL"
     gene            10381..10650
                     /locus_tag="IVZ69_002102"
     CDS             10381..10650
                     /locus_tag="IVZ69_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP8184173.1"
                     /translation="MNYKVIYMPQAQKQLKKMDRNQAKIIVAWIRKNLENTTDPRQHG
                     KGLTGNKSGEWRYRIGNYRILANICDSEIEIQIFSIGHRSTIYKR"
     gene            complement(10829..12130)
                     /locus_tag="IVZ69_002103"
     CDS             complement(10829..12130)
                     /locus_tag="IVZ69_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP8184174.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         3972 a         1973 c         2387 g         3832 t
ORIGIN      
        1 aataaatagt ttttctatca agtatattga actacgataa atttgttatt ttgttttgtt
       61 taatttcgtt gtacttattg gctttgactt cgatttcttt aaatactggg taatcggtgt
      121 ccggcaaagc tagcaaatct gttttttctg tgttccatag atcattgata atgacatgtt
      181 tttcgtaatg gattcgctct cgatcgtgtg acagctccac cgctaatgcc tcgttgaaac
      241 tggcgaaatc cttcataatc ggtgtagatg aaaagaagtt gtaccgtaca tagccgactt
      301 tgttttccat actacctttc tcgtttccgc tacgtggatt gcacacctgt gtctcaaaac
      361 catagtgcat agaaaatcgg aggaaaccgt cagtcagcac cgcttgttca gtctttgttt
      421 ttgtctaagt aacggccgtt gacatattat caatccgtat tttccgagga acgccacctg
      481 attggctgaa gagttctttc atgccttcca acaaacattc ttgattctcg gcggggagta
      541 caacggcgaa tcctgcatta ctaaaaggga aagtcatcac taataccttc acatctttaa
      601 acgctccatc gtgacaaact tccatcgtac caaaatcaag ttgcgcttct gctggcgggt
      661 gttcaagacg ctcaaagcct tggtcttcca gtgtttccaa gtagtgtgtc gctttccaat
      721 cttgaatgaa tacacagact gttcggtagg atcctggaaa gccatcggct tttaaagcag
      781 tagtcattgc ttcagcagtc ctacgctttt tatttggcag cttagcatct tctgaaagcc
      841 atagggaaac gatgcctccc cacttttctg tatacatcat accagtcttt ttgcgtgctt
      901 taggttgcgg cagcaaatca tcatctgcat attttttagc cgtgcgccaa tttacatcta
      961 gctcctttgc aatatgatta atggatttat catgattatt tcgtaaattt ctgatagtat
     1021 taatatcggt cattgtgagc atacctttct tacctccagt tacagtgtcg agactataac
     1081 tttagaggag tttcaggttg cccgcaatgg ctttttatct taacttaatc gatttgcgga
     1141 gttgtgtagt ttttcgttgc acttgtatgt acttttattc tgccataaac agcttaatga
     1201 atgtccactt gaaaaagtga ataaacgaaa tagatgactc gatttaataa ggaagtaaac
     1261 ccacacagaa atataggtga ttttccttga atgaccaaga tattgaaagt tagtgaaaaa
     1321 acacaaaaag gtagccctat tcacagaagg tctgcctttt gtgttatcgc cagcaaacat
     1381 tagagggggt atttcatata gcttttgtcc tctcgacagt cctatcagtt tctcttttaa
     1441 cttatctcta agtgctgtcc agttttaata gcttctagct tgtttcctaa ctgtgttttt
     1501 aatatgttga aggcttttga acctgtgcag tggcaagtaa ggattttttc tactcgtgag
     1561 tcattcaatt tatttccaat tttcattacc tcttgctcag gtagacctaa attatttata
     1621 taaggtatgc caatcatatg gaagccacca attaggtatt ttatgggttt agtcggaaat
     1681 gtttcaagag caatttccat catatcgata atgccatgat gactacagcc agtaaagaca
     1741 atcagaccgt cttcttgctc aattacgacc aataattcat ctgaaaaatc atcataaaca
     1801 aatttatcat ccatcttttt gtataaattc ttggtggtcg agtttgcttt gcctaggggg
     1861 atgatatgga agctcggagc aagttctgtt ttcgttttta ttgtatgtaa attctcatgc
     1921 attttaagga tttcattttt aggaatacca acatacagaa acgtggttaa aatctttaaa
     1981 taatggggta aagttacacc ttcagctgta taaatagggg cgtttcctga ttttaaatat
     2041 cttaacccgc cggtgtggtc agaatgaccg tgtgaaataa tcactgcctc cagatcattc
     2101 aaagtttccc ccattttagt cgcattatag actaattttt tattagcgcc agcatcgaag
     2161 agatatttct tccctgagta gttaattaag agagataacc catgtccact tttaaagttc
     2221 aaatttattc ttgagttttc aaataaaacc ttgatttcca ctataacatc tcctttcaca
     2281 tgaacgtgta ttcatatatt gtagcacatt aagttctatt ttttgttgta attaccgaaa
     2341 aaaatattaa tggacgcttt ttacgcttta tttcgtatgt ggaagaaaat ttcttaggat
     2401 gtggcggggg attggggcaa agctaaattc caattacagt gatcatttaa ttagacacct
     2461 ttaaataccc acactttcat caacactata atttagggaa agaaaagtgt tggcatgata
     2521 tagaaaaacc tttaattaac agcgtttcct aaaattggca cgcatcttgc ttatagaaaa
     2581 gcgtaaggat aggaggaatg aaaatggcaa ctataattct tgccagccat ggggaatttg
     2641 ctcaaggatt aaagcaaaca gcgacaatga ttattggaga tagtgtacca attcatgcct
     2701 tgtcagcatt tagagatgaa gatgaatcta ttttggtaca aataaaaaaa cttttagcca
     2761 caatagatat agaagaaacc tacattttaa ctgatattct aggtggtagt gtgaataatg
     2821 atatgctcac tattattaaa gagtatgagg gattgcaatt aattactgga atgaacttac
     2881 ctttagttat ttctattgca acctataatg gaaaaattgg ggaaagtgag ctagaaaagc
     2941 ttattaaaga gagtcaacaa tcagtgattg attgtagaaa attattagta gaacaactta
     3001 ctggaggaga tgacctatga ttaagttagt acgtattgac catcgtttgt tgcacggaca
     3061 ggtagtattt tcttggagta aatcattaaa tatcaatcgt attattattg ccaataaaga
     3121 ggcagcgaat gatgaattca aaaaaatgtc tttgaattta tctaaaccga ctggcattaa
     3181 attaacaatt ttttcagttg aacagttact agaaaaaatg cctaaaatcg aaacacttaa
     3241 cgaaaatatc atgcttattt ttggtaatac aaaagaaatt cgtcaatttt gtgaagccta
     3301 tcctaaagta caagaaatca actatggagg gataatcaaa aaagaaggtt ccaagcaatt
     3361 tagtaatgcc attttcttga atgaatctga gcaagaagat gccaaaaaat taaaagctct
     3421 tggcattaaa caatttattc aacaggtacc aacttctaaa aaagaagatt tgaatacaat
     3481 gttataaagg aggaatgaaa atgctcgttc agtcaattgg tttagggtta atcggtgttt
     3541 tttgtatttt agactcaagg cttttaggaa gaatgaattt tgaacgaccg ttgattgtca
     3601 gtacgcttgt tggtttggta cttggagaca tggaaaaagg attaattgtt ggagcctctt
     3661 tggaattgat gtccttagga ttagtaaata tcggagctgc ttcaccacct gatatgaata
     3721 tggcatcaat tattgctaca gcctttgcca ttttatcaaa tgcgaatgca gaagcagcat
     3781 taacgattgc cattccaatt tcagtgttag gtcaaatact aggtatctta atgcggacga
     3841 ttttgtcaaa tttgactcac gttgcggatc gctttatcga acaaggaaaa tttagccaag
     3901 caaggagaat tcatatactt tatggctcgg gattatatgc tctcatgtat tttattccta
     3961 tttttctagc aatttatttt ggaacgaatc ttgtttctca gattgttgat gcgattcctg
     4021 agtggctaac aaatggctta acggttgcaa gtaaaatttt accagcatat gggtttgcgt
     4081 tgttattaca aacgatgtta acgaaaaaaa tggtgccatt tttattactt ggatttttaa
     4141 ttactgctta ttctggattg ggaatcattg gtattgcagc cttcgcatgt attgttgcgt
     4201 ttgtcatggt tcaagttcaa ggtaaaaact caaatggtaa ccaaaatgag ccagatccat
     4261 tagatgactt ataaggaggt agattaagtg aaagagaaag atcaaaatgc atggaaatat
     4321 cggcagttct tatggcgttc atgggcaatt caagcctcat ggaactatga acgacaaatg
     4381 aacatgggtt ttatgtacgg aattgcacca attctagata acatttacaa gaatccagaa
     4441 gatgaagcaa tgaagaaaga agcttacgag cggcatatga tgtactacaa ctgtacccct
     4501 caaacaagtg catttgtgtt agggttaact gcttctatgg aggagcaata ctacgaagac
     4561 caagaaaact ttaatccgga atcaatcagt gcagtgaaga cttctctgat gggaccgcta
     4621 tctggtgttg gtgattcttt ctttcaagga acgattcggg tattagcctt tggactagga
     4681 attaatttag cccaacaagg tagtatttta ggtccaattc tagcaatgtt aatttccttt
     4741 gtaccttcct ttttagttac ttactatggt gggaaaattg gctataacat ggggaataaa
     4801 tacttgtcta aactgtatca agaaggtttg atggataaag taatgtatgt ttgctccatt
     4861 gtggggttga tggtcattgg ttcgatgatt gccagcatga tcgggattac aacaccaatt
     4921 caaatgggta aagcttttgt cttacaagat gtattagata gtattatgcc acaattttta
     4981 ccattaggat taaccttctt catgtactgg ttattgcaga aaaaggtcaa aacaggatgg
     5041 atgttggcaa tctgtttagt cggaggaatt atttttagtt tgttaggtat cttacaataa
     5101 gggaataacc aataaatttg gttgaataat ataaataagg aggaattcaa ttgatgaatt
     5161 caaaagaaat tgttaaagaa atcgtagcga aaaaagaggt aaaatcaatc gtatttgttg
     5221 gctgtggcgc ttcaaaagcg gacctttatc ctgcaaagta ttttctagac caaaatgcga
     5281 agcagttacg gattagtcat tacacagcca gcgaatttaa ctatgcaaca ccagcatctg
     5341 tagatgagtc aactgtcgtt atttcagctt ctttaggagg tacgactcca gaaacagttg
     5401 aagctaacgc agtagctaaa gaaaaaggtg ctacagttat tagtctaaca cgaagcattg
     5461 actcaccgtt aacaaaagat gcagattatg taatttatca tcgatttgca gagaactatg
     5521 ctgctaaatt agaaaaaaca ggctactgtt tagaattggc agtagaactt ttacatcaag
     5581 tagaaggtta tgaccattat gaagcaatgc aagaaggatt tgctactatc tatgatcttg
     5641 cccaaaaaag tgcagaatca gctcgtaaag atgcgaagaa atttgctgaa cgctttaaag
     5701 atgaaaaagt tatttatgta atgagtagtg gtgctacaca tgaagtagca tactcaacat
     5761 caatttgctt gatgatggaa atgcaatgga ttaattctgg taccttccat tcaggagaat
     5821 ttttccacgg accattcgaa attgtggata aagacgtacc gtttatatta ttaatgaatg
     5881 atggaaaaac tagaaatata gatgctcgag cattaacttt ccttgaacgc tttgatacga
     5941 aaacagaagt tgtagatgcc ttggattatg gcttgtcttc acatattgct aaagaagtct
     6001 tagactactt taacccattc gtgattactg cagtatttag agtttatgca gaagaattgt
     6061 cagaagcaag agaacatcca ttaactaaga gacgttatat gtggaaacta acttattaaa
     6121 aaatagatca aactaaataa ggtggcttga gaaattaagc caccttgttt tcttcaatgt
     6181 gattttatac atatggtaaa ataactagta catatggtaa aataactagt acatattgtg
     6241 aaagcaggtg gcaagatgca gcgattaaat gactatcttt atcaactaac attgcttttg
     6301 aaatctacgc cttcagataa ttattcagct cgcagtattt cgcaagctct acagttgaat
     6361 agaagtacaa tcagtagcta cttaaatgaa ggtgttcgtg aagggctttt cataaaagta
     6421 aaaagttacc cggttttatt tttacataga acagctcttg aagaactaca tatcacactg
     6481 aataactccg aaatagaatc aattgaaagc ttgttaacaa tttctcaaaa acccgcatta
     6541 gatcaagtaa ttggctctaa aggaagtttg aaagaagcaa ttgatcaaat taaaacggca
     6601 gtcttatatc ctggaaaagg gttgccttta ttattgatcg gcgctagtgg atcagggaaa
     6661 acctttctag cgaataaaat atatgaatat gcagtagaag aaaaggtcat tcacacatcg
     6721 gcacctttca tagattataa ttgtgcacaa tatgtgagca atccagagtt actatcctct
     6781 gctttatttg gctacacgaa aggagcattt accggagcaa gccaggagca tactggtttg
     6841 ctagaaaaag ccgatggagg agtattgttt ttagatgaag tgcatcgctt atctgaagaa
     6901 gggcaagaga aattatttac atttatggat acgggtgaat tctctcctat gggggataat
     6961 agtattcgga aaaaagccga tgttcgatta gtctttgcaa caacagaaaa tatatatacg
     7021 actttcttac caacttttct taggagattg ccagttattg ttaatctacc tagatttcaa
     7081 caacgtccgt cgtttgaacg tctgtcattg attgatgaat tttttgtttc tgagagccaa
     7141 attttagcta aggaactatc tgtttctgat gcattgattc atttcttaat gaatagtgat
     7201 tttgaaggta acgtggggaa tattaaaaat attatcaagt atgcttgcgg aaacgcatat
     7261 atccaccaga agagtcagca aacaattcaa gttaaattat tggatatgcc tttagagtac
     7321 agttataaat tcaaggagca actaaataaa cccagaaaga aaagagcaga tcgaatctac
     7381 tatccagaag aaacacgaca agtgcaacta gaaagaaaca atcagctttt tgttcaattt
     7441 tttgaccaat tacttactgg attctctgaa gtgattgaaa ataacaagga tattaaacta
     7501 tttttagaag aaatggttac caaggtaaca caagtaatgg atacgcttat ttttcaagag
     7561 gattacgaaa aagagcagtc tttatacgcc attctaaact atcatattcg tcaaagtatt
     7621 gattttatgc gagaaagcta cgggtttgaa caagatggta accgggtagt cgctttggcc
     7681 aactatctat atgtcaagga taatcaagtg atttttgaaa atagtcttca agaaaagaaa
     7741 accaaagatc agcttaacga attttttgct aatgttcttg aaacccctta ttggtatgca
     7801 aaaaaaatct taagcctttt atctgagtgt ttagatcaac ctgtgtatga agaggacatt
     7861 ttctttatta cgctatattt ttatagtttg aatgtcacga atgttaaaac aggtattaag
     7921 agtattgtgc tagctcatgg ttattctaca gctagtagta tggcgaatgt tgccaaccgt
     7981 atgctgaata agaacgtttt tcaagcttat gatatgcctt tagatattac attagagaaa
     8041 attgaagcaa aattgattca attccttgga gattatcgaa cagattcagg cttgatttta
     8101 ttggtagata tgggttcact aaaccaacta ggcggtttat tagtgaatca tctaaatgga
     8161 ccactgttaa tcattgatca tatcaataca ccgttattat tggaagtcgg ccaacaagta
     8221 ttaaacaata aaagtatcac cgaaatagga gcagaaattg aaacaagtct tactttcaaa
     8281 aagcagttac tacttcccaa gaaaaagaaa aagaaagcca tcattacttg ttgttataca
     8341 gggattggta gtgcgaccca gattcaggag attttaacga aatgcttgaa agatgcagtt
     8401 agagaattag taattattcc gtatgattac aaaaagctgt tagaaaacaa gaattttgag
     8461 actccttttc aattatacga tgtcatcatg attgtaggta cagaagatcc caaaattaat
     8521 cagattccat atattggatt agatcgcctg attaatgggg gaagcattgg cgaatttgtt
     8581 cattacttgg aaaaagagct gactattgaa gtgaacgatt tacaaaaaga attaattttc
     8641 aatttttcaa ttagtaaaat tgtcgaaaat ttaaccattt tggatccaga taaggtgcta
     8701 tcttttgtac aaaaagcaat taaagaatta tcgaagttat taaattttga tttttctaat
     8761 aatcagctgt ttttgttgta ccttcactgt agttgtatga ttgaacgaat tgtacgtaaa
     8821 gaaagtgtgg atgagcaaga ggacattgaa gaatatatgc aagcaaatgg agaaataatg
     8881 gataaaattc atagcgcttt ttttgagatt gaaagggaat acacaattga aataccagat
     8941 ttagagttgc gattattgag cgatattgtt caaggatagg agtgaattcg aatgacaatg
     9001 ggagtaattt ttgatatgga tggggtactc atagatagcg agacatttta ttttgagaga
     9061 agaatgaact tctttcaaga actggagata gatccaggat caaaccagat tgatgattat
     9121 gtggggaaaa cagaagctgc aatatgggaa acattagttc ctgaggacaa atcattaaga
     9181 gaggaacttt atccgaaata tgtagattat cgaaaaacgc atccaattga tttcgctaaa
     9241 gctttacgaa aagaagtgaa accgttactt gacttcctca agaagcggga tataccattg
     9301 gcactggcat cttcttctcc agctgtcgag atagagagta tgctcattca atgtgaactt
     9361 actgaatatt tttcctttgt tataagtggt gagtcattaa aacaaagcaa accacatccc
     9421 gaaatatatt taaaagcgaa acagcaatta gactgtgact tctttattgc agtagaggat
     9481 tcaacgattg gtattaaatc agcaaaggca gcaaatatct atacggcggc actaaaacaa
     9541 ccaatgcaaa tcgatcagag tgaagcagac atacaaattg aaagtctaca agaactggaa
     9601 caaattgttt tagaaaaagg ttagtgaatt aatggaaata aggctatata tctgtgctag
     9661 ctattttgac taaccaaaaa aacttgctat aattcaggtg tagtaaaagg tgctggtaac
     9721 accttttacg aaaatgcttc ggcagtgata atgggattgg ctttttaagt tttttatttt
     9781 gttcgcaatc cctaaggtca tgtgaatgat cctagggatt gctagaatat tttgcaacag
     9841 aaccaaaata cgaatagtta tcaagcagcc atattgactg cggtcaattt aggaggggat
     9901 actgatacta ctgctgccgt aactggtgct cttgcgggta ttctttacgg gggtgaagtg
     9961 atccctgaaa attggagaaa atcgcttcaa aatgaccagc ttcttaaaac gatcagtcag
    10021 agattttgcg ataccgtgct atctcaaaga atttgaataa tggatatgat gcaaatcttg
    10081 tttgtactaa cgttgtattg acaaaaagga ttttatttag tacaatgtta gtacaaatga
    10141 tgaacggagg tagaatcatg tctcaatcaa ccattacatt taggattccc gacgatgaaa
    10201 aagaactggt attagaatat gcaaaagcac acaattcttc attgaccgaa ctttatcgaa
    10261 atgctgtact ggataaaatc gaagatgaaa tcgatctacg gactttacgg agtgcaattg
    10321 aagtttccaa agagaaaaaa gagagtggta tttctcaaga ggaaatggag aaactgctaa
    10381 atgaattata aagtcatcta catgccgcaa gcccagaagc aattaaaaaa aatggacaga
    10441 aaccaagcta aaataattgt cgcctggatc agaaagaatt tagaaaacac gactgacccg
    10501 cgtcagcacg gaaaaggttt gactggaaat aagagtgggg aatggcgcta tcgaattgga
    10561 aactatcgaa tattggctaa tatttgtgat tctgaaattg aaatccagat attctcaatt
    10621 ggacatagaa gtacaatata taaaagataa ccgtttttgg aacgaagtag agtttcgaaa
    10681 gtcaatgtat aatcttttga attttgcata ataccacagg tagaaactac ccgatactat
    10741 cggttggttt ctgctttttt atggctcttt gtcaaatagg actgatagag tgagataaga
    10801 acatctaagg tagaattcct tttctacttt agatgttttt tgattcatag gtaatcagat
    10861 tatttagtaa gaaaattctg gtcttcattt tccgaaagct tcgaaagcca taagcgactc
    10921 gtttcaatgc tttgatgtgg gtatgcagat tttctatttt ggcatttgaa taaggcaatt
    10981 cgagggctaa acgaatgccg gattcatagt ttataaaagc tttttttata gaatgcagtt
    11041 cttttggaac ggaattgggc atcgttctta caagtttaaa gaaagtgtcc gcctctttgt
    11101 cgtgaaacgc ttgaagaatt tcttgatagt aaaaataggc gattcgtaat tcgtcagaga
    11161 tcgaaagcag acgatccacc acttcacttt cggtgagata cgcccaacca aaattgcgcc
    11221 atttggtcca tttgtcataa acaagcttgt cctgtcgttt gatcagaagc cgagacaacg
    11281 cctttaattg tcgataatat ttggcttgtg ttggatcgtt tcgatcaaag cttttcatga
    11341 ttcgtacgcg aatatcctca aatttacgaa tgagatgttt gacaatgtga aaacgatcca
    11401 caacgagttt tgcctttgga aaacattcct ttatcagaga ggcataagaa acattcatgt
    11461 ccgtcacgat gacctttacc ttcaatcgtg cgcgtcgttc aaattgcata aaataagaaa
    11521 cgagagcctt tttcttccgt gaaggaagaa tatccagtaa ttttccagta tcgccatcca
    11581 tacaagaaaa ggagtaggga ccgacttgat ttttcagtga acgaaattca tccattaata
    11641 aacaacgcgg taaccaattt ctttttactt ttgtcatggg gatcagagaa gcgagtgtcc
    11701 gagaaacggt cgaccaagaa acgccgcaat gcttagcaat tgtcgtcatt gcttgttttt
    11761 cagttagctc ttctaaaatt ttatagcgca cttgtttagc gataaagcag tttctatcga
    11821 caatgtaggt attcgccgta aaataggtgt ggcagccacg acagtggtag cgttgtttcg
    11881 ctaaagcaag ataagtcagt tggttcgcac atttattaag ttgaatgagc gattttttct
    11941 ttccgttctt aacgatcatg ccttcatgat tcatctgttt acacaaagga cagcgacgaa
    12001 tttctttact taacgtcgca gaaacaacaa gactcttgat attcttaatg ctcttcgatt
    12061 ccacatttgt gatgaaaatg tttttatctt tgattccaag tagtagtttg atatgatgaa
    12121 gatcaggcat acagaacgct cctttgattg tgttgtggtg attc
//
LOCUS       DACDAF010000078        12026 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.079, whole genome shotgun sequence.
ACCESSION   DACDAF010000078 DACDAF010000000
VERSION     DACDAF010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12026
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.079"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            560..1531
                     /locus_tag="IVZ69_002104"
     CDS             560..1531
                     /locus_tag="IVZ69_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HAP8184175.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
     gene            complement(1609..1845)
                     /locus_tag="IVZ69_002105"
     CDS             complement(1609..1845)
                     /locus_tag="IVZ69_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP8184176.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(1814..1945)
                     /locus_tag="IVZ69_002106"
     CDS             complement(1814..1945)
                     /locus_tag="IVZ69_002106"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP8184177.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            complement(2021..2404)
                     /locus_tag="IVZ69_002107"
     CDS             complement(2021..2404)
                     /locus_tag="IVZ69_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HAP8184178.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            complement(2437..3222)
                     /locus_tag="IVZ69_002108"
     CDS             complement(2437..3222)
                     /locus_tag="IVZ69_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HAP8184179.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            3400..4500
                     /locus_tag="IVZ69_002109"
     CDS             3400..4500
                     /locus_tag="IVZ69_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HAP8184180.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCGSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            4490..5314
                     /locus_tag="IVZ69_002110"
     CDS             4490..5314
                     /locus_tag="IVZ69_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphatase"
                     /protein_id="HAP8184181.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            5320..6126
                     /locus_tag="IVZ69_002111"
     CDS             5320..6126
                     /locus_tag="IVZ69_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP8184182.1"
                     /translation="MKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLANYS
                     DIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLAANF
                     AGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYPSMK
                     EVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALTSSN
                     VNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            6123..6953
                     /locus_tag="IVZ69_002112"
     CDS             6123..6953
                     /locus_tag="IVZ69_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8184183.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            6960..7991
                     /locus_tag="IVZ69_002113"
     CDS             6960..7991
                     /locus_tag="IVZ69_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8184184.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(8098..9371)
                     /locus_tag="IVZ69_002114"
                     /pseudo
     CDS             complement(8098..9371)
                     /locus_tag="IVZ69_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250512.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9648..9857
                     /locus_tag="IVZ69_002115"
     CDS             9648..9857
                     /locus_tag="IVZ69_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184185.1"
                     /translation="MDVLREYSSLFTEAYLLEQFGYKIPFADYQQGVGTAAELSFYEG
                     ISQAVGRPVDAEHFEQRISSTGKSE"
     gene            9907..10623
                     /locus_tag="IVZ69_002116"
     CDS             9907..10623
                     /locus_tag="IVZ69_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HAP8184186.1"
                     /translation="MIKEKIDSFVTIDDLQVGKPDPEGYLLCLKRLRVEQAVVVEDSP
                     VGAQAAPHMTVDVQALDADFFAFSGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMID
                     FVNLYDSSWKELPWKFEAGTPNIAGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGG
                     ITIYGPQDPEHHTGVVAFNLDGIHPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNW
                     SFKQSMIMPFERLQCRGIFE"
     gene            complement(10525..11045)
                     /locus_tag="IVZ69_002117"
                     /pseudo
     CDS             complement(10525..11045)
                     /locus_tag="IVZ69_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            11333..11986
                     /locus_tag="IVZ69_002118"
     CDS             11333..11986
                     /locus_tag="IVZ69_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8184187.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT         3483 a         2208 c         2734 g         3601 t
ORIGIN      
        1 ataacgtgat tttttgctgt aatgacaagg ttttagctgt ttcagatacc atgtatccaa
       61 aaatagttta ttgagaaaat aggagagtat ttgatactaa ctagtaggaa aaaatgagat
      121 aaaaagtaaa tggaatcatt taaggtaatc tgaaataaaa aatatacagc cctgtggtac
      181 tttacctaca aggctgtata tattttttac tctcagcgtt tttgactccg tgtctgactc
      241 cgttttattg attttgaatg ttattcaatg accatttaac aggtcaaatt tgatgttttt
      301 gattccgtat gacgccgttt gatatctagt gatatagtga tttgagtcta catcgaataa
      361 gggaataaac caataaaaaa tgatttagaa tattaaaata acaaaaaaga ggactacctg
      421 tattagtcct cttttttgac cagattttga ccagtctatt ttacatccta gtatatttat
      481 atgagctaat tttatgatta aatggtaagt ttttccttgt gtgttttagt ttaaactagt
      541 gtgtaattca aaaatctata tggaaggaac agtattaaga atagaacagg gttctctaca
      601 tgatggtgct ggtttacgga ccgttgttta tttaaagggc tgcccattac gctgtgcctg
      661 gtgttcgatt cccgaatcac aaagcaagca gattgaaaaa ggatttggcc agaccatgac
      721 cgctgaagag gtaatggatg agattgagaa ggatgctgtt ttttactttc actcggatgg
      781 cggagtgacc attagcggag gcgaggcact ggttcaggcg gattttgcta aagaaatttt
      841 gcaaaaatcg aaatacattg gaatcaatac cgtactggaa accagctttt gtggtgctta
      901 taatgaaatc caaaaggtag ctccctatgt ggatacattg tttgtggatg taaaaatgtt
      961 taccagcaag ctccacaaac aatggaccgg cttagataac caacaaattt tgaagaatat
     1021 tcgtcgcttt ttaattgagt atcctaactg cgaagtgcga attcgagttc ctgtggttcc
     1081 aggtatcaat atgaacctga ccgagctgct gacgattgct tgttttgtgg cagatcttga
     1141 tcggttcgta ccgttagaat tactaccgta ccactgctat ggtatgcacg gttaccaagc
     1201 attgggactg gagtatccgt tggcagacac gccagcgcct tcacctaaag aaatgtttgc
     1261 attggcagat caactggctc gcacggttcc tcatttgctg gtcacagctt taaccaaaac
     1321 atttatttat ttattgaatc caagctttat cttatggata aatgaaagac actcactagc
     1381 tgcagccagc tcaagaatag agcttttgct gaagtcagtg agtgtctttt tacgatgttt
     1441 tttcgaagtt aatttgtcga atgaacactg gctcaatcgg tacatcttca ctgtttgtcg
     1501 gctgagctgc gatcgctgct acgatttcta acccttggta tacctgtcca aaaacagtat
     1561 aacgaccatc cagctccggt agtcctccaa gctccaagta tgcttgcttt acattagcag
     1621 gtcagcctgc gcctttgtgt tttgcacaat aaaaaactgg ttgccgttgg tgtgggggcc
     1681 gtggtcccct aaggccaagg cgccattaaa atgataaagt ccgcgatgca cttcatcagc
     1741 gaaaaagccc tcatagctgg aaacagcttc atcaccagaa ccatccaaag cgccaccttg
     1801 aataacaaat tccttaatga cacgagccga aaggtgtgtt gtcataaacg ccttgctcag
     1861 ctagggagcg ccagttggct acagccaggg gagcttggtc aggaaataag cggagacgaa
     1921 tttcaccagc atcggtgacc agcacacaaa cttcttcctg ctgcggtttt tctaattgaa
     1981 agagaggaag gtttgcaact gaaacgcctt gatcctgcca tcaaatatcg aaaatccgcc
     2041 actcgacctt cgcctgatca ccaaggcgag ccattcccaa taaaacggta taggcggttt
     2101 catccgcttg aaaggtcaat tgcagctgtc ctcgtaaatc gttgtagtca tctggggcgg
     2161 ctacttgata aaaaagatga aactgcgcat gcaaatattc caaaggctga tctttaaagg
     2221 ctgcaaaata agcctgaact ttttcccgct gcaagctgtc agccaccaaa aaattttcca
     2281 gttgttgttt tggaacggct gctaacaagg atcggcaaac cgcctcaatt ttcaacgcat
     2341 cccaatgtcg cgcaattaaa taatggatgg gtgcctcttg attgtagtcc cacaggttgc
     2401 tcattttttt caccactttc ttctattata taggaatcac aaaatcggca gcggcgtcag
     2461 gcggcgttct tttccttgaa tgactagcaa cttttctacc tgacagtctg ccaacagctg
     2521 actcattttt ttaaagccca gctgataatc ttcggcaaca tgagcatccg agcctaaggt
     2581 aaagagcttt ccgccgacac tttgatacaa aggaacggca taacggtaaa ggtcttcgtt
     2641 gccgtatttc aagaagctct tggcatttaa ctccatcgcc aattctcgtt caacaacctt
     2701 tttgaaaatc gttagcagct gagcctcaaa atgctccgcg aattcttccg ctgtgaaggt
     2761 gaagcggcgt aatccataat caaagtgagt caaaatatct ccttctggaa aatccgtcaa
     2821 gacctgcaac atctgatcaa aatattcctt ggtagtttga atgggatctt tggttaaaac
     2881 cacatcgtcc atataatcaa agcggccatt ttgatgaata cttaccagct ttaaatcata
     2941 aggatgctga gcgaggtaat ccacgatccg ctcttcttgt cctggaacaa cgccaatctc
     3001 gatacctcgc agaaatttgg tggaataggt ttcttttaaa gagtccagtt tgtttatata
     3061 ggctggataa tccggaatgt catcttttcc ggtagatgga ttgtttaaat caaagtgatc
     3121 cgtagaaacg aaaaactccg gctgataggc taaatagttt tcaaattttt cctctgaatc
     3181 aaaggaaaaa tacgtgtgga gatgctgatc ataatactgc atagggagcc tccttttttc
     3241 tactatcata ccgcaaaagc tttagaaggt taacgggaat tcgtcgaaat ttacaaacca
     3301 tatacaacct ttacattgtt catgaaacct tttcaagaaa ctgattctct cattacaaag
     3361 ctttgttaga atggaattat cgaaagggga gaagaatgaa tgaaaatgaa tgaaaaaatt
     3421 cgtaacatga ctatcggttt attttgtgca gcaacagtaa gtatcctgct gacaggctgc
     3481 ggctcaggtg aagcaacgaa gcaatcggct gcggcagacg actctttaga tacgattata
     3541 gaaaaagcca aggaagaagg agagattgcc agcttgggaa tgccggatac ttgggcaaat
     3601 tgggtaggca cttggaacga ccttgaaaaa gaatacggct taagtcacgt ggatacggat
     3661 atgtccagtg cagaagaatt ggctaagttt gaatcagaag gaaaaaatgg aaccgccgat
     3721 attggtgatg tcggtatcag cttcggtccg ttggctgaaa gcaaagagtt aaccttacct
     3781 tataagacca actattggga ggaaattccg gattgggcaa aggatgatga tggggattgg
     3841 ttgttaagct atacgggaac catttccttt atcaccgata aagagaatgt gaagcaagca
     3901 ccgactagct ggaaggagct gcaagagggt gactatcaag ttagcgtggg ggatgtgacg
     3961 attgccaacc aagcacaatt tgctgtattg gctgcggcga ttgccaacgg aggtgacgaa
     4021 aaggatattc agccaggtct gaattactac aaaaaaatgg cagaaaaagg ccgtttgtcc
     4081 accgttgatg ccagcgtagc aaatcttgaa aaaggtgaaa tcgatgtggc agttgtttgg
     4141 gacttcaatg gactaaatta tcgtgaccaa attgactccg agcgttttga ggtaactgtg
     4201 ccaacagacg gctccatcat tagcgggtat acaaccttaa tcaataaaaa tgcccctcat
     4261 cccaatgcgg caaagctagc acgggaatat attttatctg atgaagggca aatcaatttg
     4321 gcaaagggct atgcgcgacc tattcgcaag gtagagctgc ctaaagaagt agctgaaaaa
     4381 ttactgccgg aggatgctta tgaagcggcg gtgccagttg aagacaatga agcttggaac
     4441 aagacctctg tagagcttcc agagctttgg caggcggagg tactgaccta tgcaaagtag
     4501 acttgacaaa ctgattgtag ttatactaga cggctgtcgc tacgacacag ccgtcgccca
     4561 gcttgggttc atgaatcatt tagttgagca ccagcaagca agcttattga aggtaaaaag
     4621 tgagctgccc agcaattcac gtccgttata cgaagtactg atgaccggcg ttccagccta
     4681 tgaaaatggc atctatagta attaccatgc tcagcgatcc aaagagtggt cgctgtttga
     4741 attagttaag gaagctggcg gaaaaacagg agccgccgct taccactggt acagcgagtt
     4801 gtacaatcaa gccccctata atcgtttggt tgatcgcatc cagcatcagg aggagcgact
     4861 gattcagcat ggcatctttt atagtgagga cacttaccct gattcgcatt tatttgcgga
     4921 tgcccattat ttagtgaatc agtatcagcc agactttttg gtcgtacatt cgatgaatat
     4981 tgatgatgtc ggtcacaaat ttaccgccga ttctcatgaa tatgcagcag cggttaatca
     5041 ggcggacaga ttattggcta tttaccttcc tgaatggctg caaaaaggtt atcaagtcgt
     5101 ggtgactgcg gatcacggga tggatgcgca cggactgcat ggcggcagct tggctgcaca
     5161 tcgtgaagtt cctttttatt tgatttcaaa taaacgccaa aagctgaagg aacaaactgt
     5221 accacagctg ctggcggctc cattgttttg ctggttatta ggaattgcac cgtcagagaa
     5281 aatgcaggac attcaagaat tgatgagggg atgaaagaga tgaaaaaacg cttggttctg
     5341 gttcctgcct cctttatctt ctgtgcattt ttactgctgc cgctgctttt tatggttctg
     5401 tgcagcttgc acagtgattt aactaaccag tggacattgg ccaattacag tgatattttc
     5461 agcaacaaat attacacaca ggcctttgtt aacagcgtac tgattgctgt cagctccagt
     5521 gtgattgggt taatcgggac gtttatttta tgtttatgct taatgaatct atcgactaaa
     5581 ttgcaggaga aaatcacctt tgtttccaat ttggcagcta attttgctgg gattccgctg
     5641 gcattctctt ttattatttt gttggggaat gtaggtgtgc tgaaaatgat tttgccattt
     5701 ctagcggact tcaatttgta ttcttggtgg ggattgacca tcacgtatac ctatttccaa
     5761 attccgttag gggtcttgtt tttgtatccc agcatgaagg aagtgaaaaa ggaatggctg
     5821 gagtccgcac aattgctggg cgcttcatca gcgtatgctt ggttcaaggt ggctttgcct
     5881 tttttgcgac catcgattgc cagcaccttt gtcatcttat ttgctaatgg catggggacc
     5941 tatgaaacag cgtatgccct gaccagcagt aatgtaaatc ttttaacgat tcgaattgcg
     6001 gctttagtgt cgggagatgt gttcgccaag cctaatttag gcagtgcgtt ggcagtcgct
     6061 ttaggtgtcc tgctggtaac ggcaatgttg attattcaaa agaaaggcaa ggtggtgcag
     6121 acgtgaaaaa gttaataaaa ccgattttgt tctgctttgt cctgtattac ttgctgccga
     6181 ttattggaac gattttgtat gccagctcca ctaaatggtc aaaatcgctt ttacctagtg
     6241 attttacctt gcaatggttc caacagctgc tgacggacag ggaatttatt gctgcggtgg
     6301 gtcgctcact tttattagca ggtgtggtct tggtgacgat tctgttgttg atgattccca
     6361 ccattatttg gattcatttg tatttccctc gtttgaatcg ttggctggaa aagctgctcc
     6421 tgctgccgta tgctttacca ggagtgattt tggtaacggc tttgcttcga acgtatgctg
     6481 aaactggtat cccaatgttt gtagtgttgg taggtgcatt gtttattacg gcgttgccga
     6541 ttgtctatct tagtcttaac aaccagatgc gcttaattaa tctgaaggaa ttagtggatg
     6601 cagcagaaac cttgggcgcc ccgatgtcta cgattattat ccaggtgctg tttccaaaca
     6661 tccgtatcgg tgtgacccta gtttctctga tgattttttc ttcggttttt ggggagtaca
     6721 tgctgacgaa cctgttgatt ggcggtcgat ttcagacggt acgcatctat atgctgcggc
     6781 ggatgaacga aaacggccat ttggctagcg ctgtgatggt tttgtatttg ctgtttatgg
     6841 tgggaattgc tttaactacc tttatgctga cttatcgaca aaagcaacag ctgtccctta
     6901 agcagacgag ggaagagaag cagtcgaaaa agaagccctt aaaggagttg tgacggaaaa
     6961 tgtttttaga aatacatgat ctcaatctgt tttttgatga aaaacagatt ttagctattg
     7021 atgaaattca gattgaaaag ggtgagctgg ttactttact aggtcccagc gggtgcggaa
     7081 agtctacgtt gctgcgctgt atcacgggat tggaacaacc aaagagcggt gagattgtgc
     7141 tggacaatga gaatattgcc gataagccta cgaaggatcg caatatcggc tttgtttttc
     7201 aacagtatgc attgtttcca actatgactg tttttgaaaa tgtagccttt ggtttgaagg
     7261 taaagaagct gagtcctgag gtgattcagg aaaaggtttt tgagatgcta tcattggtgg
     7321 atatgacgga gcaggcagat aaaaatgtcc agtttctttc tggcggtcaa cgacaacggg
     7381 tggcactggc tcgctcattg gtcactgaac cgaaagtcct gctgctggat gagccattaa
     7441 gtgctttgga tgcccgaatt agaaaacagc tgcagcggga tttgcgcgct atccagcaat
     7501 cgctagggat gacgatgatt tttgtgactc atgaccaaga agaggcgatg cgaatcagtg
     7561 atcggatttt tgtgatggaa gctgggcggg tggctcaggt ttccacctcg aaggaattgt
     7621 atcagaatcc tcagagccga tttgttgcgg aatttatcgg caactataat cgtttcgaat
     7681 ggtatgagct gaatcagtat acccacgagt tttccgctaa gggcaatcgc tgcatttatt
     7741 atttaagacc ggagctgatt caatttgaac cggttcctca gggggttaag attccggttc
     7801 tatggaagga atcatttatt ttaggcaaca ttcaacggta tgtttttcaa acgctggagg
     7861 gcaaagaaat tttagtggat cggttgaacg atcgggaaga gaaaattagc gatgccttat
     7921 acattcagct gaaagatatt ctagcaatcc ctgtggaaat tgatactcag cattttgcac
     7981 aacaaagcta gtgtatagtc ggcaaacatt tctggctctt tgtcaaatag gactgataga
     8041 gtgatataag aacatctaag gtagaattga ttttctgctt tagatgtttt tttatgttta
     8101 ataagtgatc agatgattga ttaagaaaat tctggttctc atcctaaccc gtaagctatt
     8161 cgtttcaatg ctttgatgtg ggtatgcaga ttttctattt tgccatttga gtaaggcaac
     8221 tctaaggcta aacgaatgcc ggattcatag tttataaacg ctttttttat atgatgcagt
     8281 tctcttggaa ccgacttggg cattgttttt acaagctgaa agaagatgtc cgcttctttg
     8341 tcataaaaag cttgaagaat ttcttgatag taagcataag ctattcgtag ttcatcagaa
     8401 gtagaaagta gacgttctac gacttcactt tcggttaaat aggcccaacc aaaattacgc
     8461 cattttgtcc atttatcata aacaagcgtg tcctgtcgtt tgatcagaag tcgagataaa
     8521 gccttcactt gtcgatagtg tttggcttgt attggatcgt ttcggtcgaa gcttttcatg
     8581 actcatagtc aaatatcctt aaaactgcga atgaggtgct tgacgatgtg aaagcgatcc
     8641 acaacgagtt tggcatgagg aaagcactct tttatcagca aagcataaga ggcgttcata
     8701 tctgttacga gtatttttac gtttaaacgt gcacgtcgtt caaattgcat aaaataagaa
     8761 atgagatctt tcttcttacg tgaaggaaga atatccagta atttcccagt atcgccatcc
     8821 atacaagaaa aagaataggg accgacttga tttttcaatg aacgaaattc atctaccaat
     8881 gaacagcgag gcaaccaatt tattttcacg tttgtcatgg ggagcagaga agcgagtgtt
     8941 cgcgaaacgg ttgaccaaga aacgccgcaa tgtttagaaa tcgtcgtcat tgcttgtttt
     9001 tcagtcaatt cctccaatat tttataatgt acttgtttgg cgataaaaca gtttttttca
     9061 acaatgtagg tattcgccgt aaaataggtg tgacagccac gacagaggta ccgttgcttt
     9121 gccaaagcaa gataagtccg ttgattcgca cacttattga gaaggaccag cgattttttc
     9181 tttccgttct taacgatcag cccatgttga ttcacctgtt tacactgagg acagggctga
     9241 atcgttttaa tgagcgtggc agaaacaacg atactgttga ttgaatgtat ttttttcttc
     9301 tcgacatgag tgatttgaat gtttccatct ttgattccta gtaatagttt gataagatga
     9361 agatcaggca tacagaacgc tcctttgatt gtgttgtggt gattcaattc taacggagct
     9421 tctgtatgtt ttgttttttt atgctcaaaa ggactgatag aatgatttac tatcagtcct
     9481 agaaattata gcgccacatt tctttcacct ttgacttttc agacggcagt ttttatgctg
     9541 atactgtaga gagagcagga cacagctttt gcttgttttg ggtaaggggg aaagaagatg
     9601 accaaagcac ttatttttga ttttgatggg acgatgattg acagtgaatg gatgttttac
     9661 gagagtattc atcactattt actgaagcct atttactgga gcagttcggc tataaaattc
     9721 cttttgcaga ctatcaacaa ggtgttggga cggcagcaga actgtccttt tatgaaggga
     9781 taagtcaagc ggttgggaga ccagtggatg ctgaacattt tgagcagcgg atcagcagca
     9841 ctggaaaatc ggagtagtct caattctgaa ctgcgggagc tagactattt ttttgaagca
     9901 catccgatga ttaaggaaaa aattgattcc tttgtgacga tcgatgatct tcaggtcggc
     9961 aaaccagatc cagaaggtta tttgttgtgc ttgaaacggc tgagggttga acaggctgtt
    10021 gtagttgagg atagtccagt cggtgcccaa gcagcaccgc atatgacagt tgatgtacaa
    10081 gcgttggatg cagatttttt cgcctttagc gggcataaaa tgtgcgggcc gacaggaatc
    10141 ggtgtattat atggcaaacg tcaattgtta gaacaaatgg agccagtcga attcggcggt
    10201 gaaatgatag attttgtcaa tctttacgat agttcatgga aagagctgcc atggaaattt
    10261 gaagctggta ctccgaacat tgcaggagca atcgattact tgaatgagat tggtatggag
    10321 aatattcatc gttatgagca agaactggtt gcctacgttt tacctaaatt acaagcgatc
    10381 ggcggtatca ccatttacgg accgcaagat cctgaacatc atactggcgt ggttgctttt
    10441 aatttggatg gcatccatcc ccgtgatgtg gcgactgctc tggatatgga aggtgtcgct
    10501 gtacgttcag gacaccattg tgcacaacgg ttcatcgacg atttctgttt gactaattgg
    10561 tcgtttaaac agtcgatgat aatgccgttt gagcggctcc aatgtcgtgg aatctttgag
    10621 taagagtttc caatatcgct tgagccgacg gtacttcttc tgattttcag attacgtgat
    10681 tgattttcgt acagttctat gagaatcgcc tgcttcagtt cctttgttag ttgatgatgt
    10741 tcatcaacta agtccgtttt cgcagaaaag gtctgcccac aatcatagca tagaaaacgg
    10801 gtacgtttta attctaaaat agtcaacttt tctttgactt tcaacatctg agtacgtgtc
    10861 gtataggaac cgttgcggat aatacgaatc gatccacagt gttcacaatg ggaaggtgag
    10921 tcatccaatc tccctttaat aaactgcgct tgaacgcctt tatattcttt ttcaatcagc
    10981 cattcttcat caaaaaataa atgtttatct gttaatccga gtaattttct agtatgatta
    11041 tccatagagc gactcctttg gtagggtgat gttttggtcg actaaatttt accaaaagtg
    11101 agtctctttt tgagttgaaa cgaagaaaaa gtgttagtag aaaatcgcct tcgattttcc
    11161 aacaacacaa aatattatag aagccttttt tctaaaggat ttcaaggtgt ctgtttgcat
    11221 ttattaaaaa aaagaaaaag tattggcaac agaaggcgtc accaacacta gatattatag
    11281 agccataata tgctgtataa tatctagtgt ataggcttaa gtggaggtat atatgaaaat
    11341 attaactgtt gaagatgata atatgataag agagggaata agtgaatatc tttcagaatt
    11401 tggatatact gttattcaag ctaaagatgg aagagaagcc ttgtcaaaat ttaatagcga
    11461 tataaatttg gttatcttag acattcagat accttttata aatggtttag aagtgttgaa
    11521 agaaattaga aagaaaagca atttaccaat tctaatcttg actgcattta gtgatgaaga
    11581 atataaaatt gatgcattta ctaatttagt agacggatat gtagaaaagc cattttcatt
    11641 gccggtctta aaagctagaa tagattcttt aattaagaag aattatggac atttagagaa
    11701 gtttgaatat aaggatctat cggttaattt taatagctat acagctaaaa taaatggtga
    11761 agaaatagat gtaaatgcaa aagaactaga agtattaaaa tgtttattgg ataataatgg
    11821 acaagtgtta acaagaatgc aaattattga ttatgtatgg aaagatagcg aagaaactcc
    11881 ttatgatcga gtaatagatg tatatataaa agaacttaga aaaaaattac aattagactg
    11941 tataactact ataagaaatg taggatataa attggagaga aaatgaaaaa attaaagata
    12001 tttccaaaaa tgttcataca aatatt
//
LOCUS       DACDAF010000079        11638 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.082, whole genome shotgun sequence.
ACCESSION   DACDAF010000079 DACDAF010000000
VERSION     DACDAF010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11638
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.082"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            573..1727
                     /locus_tag="IVZ69_002119"
     CDS             573..1727
                     /locus_tag="IVZ69_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HAP8184188.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAIKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVHATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1721..2143
                     /locus_tag="IVZ69_002120"
     CDS             1721..2143
                     /locus_tag="IVZ69_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184189.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2445..2825
                     /locus_tag="IVZ69_002121"
     CDS             2445..2825
                     /locus_tag="IVZ69_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HAP8184190.1"
                     /translation="MSEQNQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            2807..3721
                     /locus_tag="IVZ69_002122"
     CDS             2807..3721
                     /locus_tag="IVZ69_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP8184191.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            3961..4650
                     /locus_tag="IVZ69_002123"
     CDS             3961..4650
                     /locus_tag="IVZ69_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184192.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQVLAQKIEKFTA
                     CYEDMNDIFVKQEKRLTDKNMETLTRLYRNLPEEQQKEYQEKYEQVKKDVQYVKDTKV
                     EEACSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQAINIQNLTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(4770..4856)
                     /locus_tag="IVZ69_002124"
     CDS             complement(4770..4856)
                     /locus_tag="IVZ69_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP8184193.1"
                     /translation="MFELFICPLLVGVCISVFSYWLNNRNKK"
     gene            5502..6434
                     /locus_tag="IVZ69_002125"
     CDS             5502..6434
                     /locus_tag="IVZ69_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP8184194.1"
                     /translation="MANEIVKYEPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFSQLKDLSAYKQTAGEVFIKDLARTYDHLMDLRFGRKSNGGLTIERFTMFTDFEIH
                     GEVDNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRIKLFNIEHNGELTQKEKWRAKDRILNLPLGTHEAD
                     FKKQQQTEKEEAEKQSISNELKQDLLENLQNLFD"
     gene            6451..6921
                     /locus_tag="IVZ69_002126"
     CDS             6451..6921
                     /locus_tag="IVZ69_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP8184195.1"
                     /translation="MIDKTIKELAEEFHVSKQAIRKRLSADFRENYVQTVTRNGVKTL
                     VVSYKGYLLLKQHFLGSNTTGNQVETVASNDENSIIVFLHEQLQEKDTQIKQMQKLLD
                     QQQQLTLQANQQIEKLQEQLQLAYTEEPEEEELTSVNKENNNAITTEKKWWKFW"
     gene            7005..7309
                     /locus_tag="IVZ69_002127"
                     /pseudo
     CDS             7005..7309
                     /locus_tag="IVZ69_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302541.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            7584..8765
                     /locus_tag="IVZ69_002128"
     CDS             7584..8765
                     /locus_tag="IVZ69_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP8184196.1"
                     /translation="MKNNRIYKNQLNYGLLLPVFLLCIIGLLSLYVALYHDSYTNSKI
                     TKELIKQVLWYSIGFTSAITIYFFNPKILWKLTPIFYGLCIIMLLLLLKFYNPQLAVL
                     TGAKNWFYIAGFSFQPTELVKIGYTLMLAKITVNYQQKSITSNTKDDWIYLLKTFIAT
                     LPIGILLFFQNDLGTMLVFIVIYIFILFTSNINIKIIAPIIAIGVVLSLIFLYLVISD
                     TGRDFLLKIGFHDYQFKRIDSWLNPFLDPNGSSYQLANSLIAIGSGGLLGTGFNVSNI
                     HVPVRESDMIFSVIGENFGFIGSCLVIFLYFYLIYQMYKTCFKSNNLFFTYIGIGIVA
                     MIFFHVFENIGASIGLLPLTGIPLPYISQGGSAILSNFLGLGFMLCCSRYTNEKKGTQ
                     K"
     gene            complement(8994..10142)
                     /gene="tnpB"
                     /locus_tag="IVZ69_002129"
     CDS             complement(8994..10142)
                     /gene="tnpB"
                     /locus_tag="IVZ69_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family element transposase accessory
                     protein TnpB"
                     /protein_id="HAP8184197.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHRQPKGIIKSATISRHSS
                     GKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFTSKMEKKLKREQ
                     RKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNKLSTEMIKNHDI
                     ICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKVDKWFPSSQICS
                     ECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGLA"
     gene            complement(10159..10563)
                     /locus_tag="IVZ69_002130"
     CDS             complement(10159..10563)
                     /locus_tag="IVZ69_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HAP8184198.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT         4182 a         1890 c         1906 g         3660 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattaa attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaacaaacg gataaataat aaaaaagact
      181 gctctttcga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcacgcgctt
      241 atgaagcgct accaaaaatt taccatattt tacaaaaaat aacaagtctt aaaaaaatga
      301 cagataaaaa tgcacaaaga attagatata gataaccgcg aaaaatcaag ctttagaaag
      361 ttgcttttag ctagaccaat taaaaatcac aaagtgagcg tctctatcca ttggtagagg
      421 ggctacttgg catagtgtac attatgttaa ctaacgctat aaataacgat tatgttccca
      481 aaacaatatt ttatgaacta taacaaaaat ttgttatcgc atattgtata ttttaattat
      541 aggtgtatac cacttaaatt taacacaaag gcgtgattat tttgaaaccc aaaaagaaaa
      601 tttatctagg tctcctcttt tccttgatga ttggaatttt tagtatagga attacaaata
      661 cctatgcttc agaaaattct aatttcaata tcaactccca accaattgaa gaacaagcaa
      721 ttaattttgc gaaaactgat tttgaacact ccataacttc aattctttta atggaaaata
      781 acaccgaaac tgatattaac tatactcttg gttcgccatt taaaatgctc gatggagaaa
      841 atacggcaaa tagttctatt ttctttccag tattttcaga cgctgataat acgattaaat
      901 atatttatac cgtcaaaaaa aatacaaatg gagaatattc aggaagtatt tcacaatttt
      961 tagcaaaaga acttcaaaat ctagtagata gtaatataac agatacaacc ttattttttc
     1021 aagataatag catttattat tccgataatg gacaaattaa actactttgg aaatcacctt
     1081 taagtacaga aaaaaatggt gtttcttcct ttacagaaaa aaatgatctt atatccgtaa
     1141 atataaaaaa taaaattaaa aatttctcta aaaaacaaaa ttttcctgcg attaaacgtg
     1201 taaaaagtgt ctcctccgga gataacttta ttatgattaa ttggcgtata gcagaaaccc
     1261 aaacaagttt tccgtggtgt gctgcttacg tagaagctgc tatcttatgt aacaaaacag
     1321 atgtacatgc tacttcagct agagccatta tgcattatac ctatcctaat ttaaacaaca
     1381 gtcaaattga atcaaaaagt cttaatcaag atcaaataat aaaatatgca aattactgtg
     1441 gtgtttatcc taaaaaagta gcacgaatac taaacctttc agaggtccaa acacaactaa
     1501 gaaaaggaaa tgccatttat atgggaactg ctggttatgg aaattatagt aacagccgtc
     1561 atgcacttgc attatttggg tgggtcaatc aaggtggtta tcaaacttac tatgtgtgga
     1621 atccttggta taactaccca actgtaataa gtgcaaatgc aggaccagtt acaattcctg
     1681 tacctggagg tggttttact tgggacaata ccattacaaa ttggtaaata aacccattgc
     1741 tttagttatg ggtctagtgt tagttctttt cttaactagt tgttcaaaaa aacaagaaat
     1801 acaaaagact gatctgattc cttttctagg aacttggcaa actaaagatc attcagaacg
     1861 tctagtaatc actaatttaa atacttcaaa aaatatagaa caatatacca tcttagtaaa
     1921 agagaacaat cataaaattc aaatcattga taaaaattta aatataaatg aacaagtttt
     1981 catttacaaa gcaacaaata atttactaac actgcgctct aataaaaaac aattagatta
     2041 cacttttagt ttggattctc caaaaaagct cgtatttatt ttgacaacga atgatgggac
     2101 agaagggaca gctaaaccaa ttgaattttt taaagctgat tgatgaatag ttgtttgata
     2161 ttacaaaaca ataatttcac cgaaggtgaa acaagcgaaa ctttacaaaa agtggctagc
     2221 atttgctagc cttttttgta ttgtggagcg tgggttttga gggggattca agggggagct
     2281 tgcgcccctt tgaaaagcgg ttatttgcac caaatacgta ggtatttggc tagcaaatat
     2341 agagcttgcc aaaccctttt agtgagcttt actcattgta cctttttagg tacaatggta
     2401 ttgcgaacga tacgtccgta ggacgtactg aaagggtggg acttatgagc gaacaaaatc
     2461 aaaatttggc tagcgatcat tctaaaaaat atacctatcg atccgagcca aaacaaatca
     2521 gttttcgagt gagcgaatct gaatttgcaa agctgaagca gtcagctgaa gctttgcaaa
     2581 tgagtgtgcc ggctttcgta aaagccaagg cacaaaacgc gcgtctggtg acaccgaaag
     2641 tggcgccaga cattgcccag gcaatcgcgc gcgatttagc caaagctgga gggaatatca
     2701 atcaaattgc taagtggtgt aatacacacc aacacgacgt tgctcctgga gacgcccaac
     2761 gcttatccga aaacctaaaa atcatgcaaa aggagctaca aaagatatgg caacagttaa
     2821 agtaagccga accacttctt gtagtcgtgc aattaattac gctgaaccac gagcaaccat
     2881 taaaacagga ataaactgtg acgtcgatta tgccaaaagt gaaatgaaac aaattcgcat
     2941 gctgtatgga aaagacgacc gtgtacaggc acacttattg attcaatctt ttcgaccagg
     3001 agaaattacc gctgaaaaag ctaatcaact aggggcagag tatgcaaaaa aaatagcccc
     3061 cgatcaccaa atagctattt acacacatac agacaaagac catattcata atcacattgt
     3121 cattaactcc gttaatctgg agactggaaa aaaatttcaa gctcatggtc aagcatttct
     3181 aaacaaatgt tatgacctaa atgacgagat ttgtcttgca cataacttac caatcactga
     3241 gcgaggaaag aaaccagaaa aacgaaccat gtctgaaata aaattaaaag aaaaaaatga
     3301 acctgtttgg aaagacgaaa ttcggattgc gatcgatcaa acaatgaaaa acaaaaaaac
     3361 cagaacctat gaccaatttt gtaattccct caaaacattg gggattcatt gcttcaatcg
     3421 cgggaaaaat ttcacttacg aattgatcca caaaaagaaa aaagtacgat ccaacagact
     3481 aggaaaggac tacgaaaagg agacgatttt acatgagctg gacagacgag aacgaaccta
     3541 taaccaacag cgaaccaacg agctacgaag agctcgagct agcattcgcg aaactgcaga
     3601 agaagtacga agagaacaac gaactcttac gcctgaacaa ccggaaatta gaccggctcg
     3661 aagaaaccat gaacaacacg ttgaaagagg aacagaccac caacaagaat tatcgctcta
     3721 aaacgttaaa agacatagaa aacgaaataa agaaacaacg tgcttttctc gttccttata
     3781 cgcaagaaag gatacaaact acgattgatt tacaagttaa aaaactccat caagagctat
     3841 tagaccagcg aaataaggaa cagaaaaagg tgcttattca acgatcattg gattttcttg
     3901 cccccttatg ttgcttagtc ctgacactgt tcgcattttg gttagtatgg ggaggctaaa
     3961 atggcatttt atttacccta tctactcatt tttgttagta tttcaggaag tatttggctc
     4021 atctataaaa tttttcaaac aagatattca ttaaaaggct ctaaaattcg atttaagcga
     4081 tttttctttc ttggctgtat attttccttg ataatcgttt caagcggctt attcggcgtt
     4141 ttagagggaa ataagcgcgt ttctagaagt attttattag gaaatgtcac tcaaaagtat
     4201 gaatcagcgc gtgataaaaa gaaaaaagag caagtattag cacaaaaaat agaaaaattt
     4261 accgcttgtt atgaggacat gaatgatatt tttgtgaagc aagaaaagcg tttgacggat
     4321 aaaaatatgg aaacactcac tcgactttat cggaatttgc cagaagaaca gcaaaaagag
     4381 taccaagaaa aatatgaaca agtaaaaaaa gacgtgcaat atgtgaaaga tacgaaagtg
     4441 gaagaagctt gtagtgattt atttggagat acaattcctt tttcaactag cgaacaagaa
     4501 cgaaaagaac gacaacaatc agtcacatat gaacgctatg aaatcttgct tcaacaagca
     4561 attaacatac aaaatctgac taaaaaagaa acagctttaa attatttaaa aagcgtcaag
     4621 gaatggttag atcagcaaca gcaaaattga atttgattga aattcatgtt aaactaaaca
     4681 tgcaaatgtt caaacattag atacacgaaa gccccagaga ggtcggattc tctggggctt
     4741 tttttaggtt gatgtcgcct ttactgattt tacttcttgt ttcggttatt caaccaataa
     4801 ctgaatacag agatacaaac tcctacaaga agggggcaaa taaacagttc aaacatcaga
     4861 tacacctcct tccagtcgca agactgtcgg ataggcgaca agttattata ccctacaaaa
     4921 ttaaatctgt gtggcaattt taagtatctc ttatttccgg gttgttaggg cttgccctga
     4981 ccgcctgtag ggcgctttaa atgccagata aaggttttta tactaagact gtcttaaaac
     5041 ggcttagaca agctcttaga gcctcaaccc tcctttttga acaatggttt tagcaaagga
     5101 gctggaggcg actgcgcagg tataatgtga gagcgtagcg atcacacctt tttggcgacc
     5161 gtagggagcg aggttttgaa ttagcagttt agaaaagttc gcgaacctgt ttaaagaaaa
     5221 aataattgtt tttttaggtg ggaaattttg tctccctctt ttataatctt tttttaaacc
     5281 tctttttaaa cctctttacc gtcggctgtg tccttactcc cccaagggat acaaaatttt
     5341 ataggcatga aattatctgt ttataggcat gaaattatct gtttataggc atgaaattat
     5401 ctgtttatag gcatgaaatt atctgtttta ggtattgttt ttagacataa tatgtcctaa
     5461 aatgatgtca ataaaatcat ttagactgga gtaacaacta aatggcaaat gaaatcgtaa
     5521 agtatgaacc agaattaaat accattcctt taagaaaatt taccccaata gaaatgaact
     5581 tgtttttttc tattgtctct agaatgcgcg ataaaggtaa tcaaaaaata cgcttttatt
     5641 tcagccaact taaagattta agtgcgtata agcagactgc aggagaagtc tttataaaag
     5701 atttggcaag aacatacgat catttgatgg atttacgttt cggaagaaaa agcaatggtg
     5761 gattaacaat agaacgattt acaatgttta ctgattttga aattcatgga gaagtcgata
     5821 acccttatgt agatataaaa gtccacgaaa aagctttgcc tttacttaat aatctagaaa
     5881 gctgggtacg tttctcttta acagaatttc gagatttaaa tagcagttat gctaaaacaa
     5941 tgtttagatt gctaaaacaa taccgaactc aaggatgggc tgaattttct aaggaagatt
     6001 ttttagagct attagatatt cctaaaagct atagacaaac aaatataaat cagtttgtac
     6061 tcaaaccaat aaaagaagaa ctaactccac tatttaaagg attaactatt cgtaaaaaat
     6121 atggtaaagg tcgaggtaaa cctgttattg gttatcgttt tacttggaaa gctgaaatca
     6181 accatgctga cgatttttca aaagggaagc aagaagattt acgtataaaa ttatttaata
     6241 ttgaacacaa tggagaatta acacaaaaag aaaaatggcg tgctaaagat cgaatactaa
     6301 atcttccgtt aggtactcat gaagctgatt ttaaaaaaca acaacaaacc gaaaaagaag
     6361 aagcggaaaa acaatcaatc tcaaatgagc ttaaacaaga tttattagaa aacttacaaa
     6421 acttattcga ttgaagcata aggagtattt atgatagata aaacgatcaa agaactcgcg
     6481 gaagaatttc atgtttcaaa acaagcaatt aggaaaaggc tatcagctga ttttagagaa
     6541 aactatgtgc aaactgttac taggaacgga gtgaaaacct tagttgtcag ctacaaagga
     6601 tatttgcttt taaaacaaca ttttttaggt agtaacacca ctggtaacca agtagaaacc
     6661 gttgctagta acgatgaaaa ctcgattatt gtttttttac atgaacagct ccaagaaaaa
     6721 gatactcaaa taaaacaaat gcaaaagtta ctcgaccagc aacaacaact caccttgcag
     6781 gcaaatcaac agatcgaaaa actgcaagaa cagttacaat tagcttatac ggaagaacct
     6841 gaagaagagg aattaacttc tgtcaataaa gaaaacaaca atgcaataac aacagaaaaa
     6901 aagtggtgga aattttggta acaattacca actttccata aagaagaaat caatttctat
     6961 agactctatc tttctaagaa taaaaaatat gtttaggtga tcaaatgact ataagtaaag
     7021 taatcaaaca aaaaagaata gaaaaacaac taactcaaga agatttagct gaaatgcttt
     7081 tagtatctaa aaaaaccatt tctaattggg aaaatggtcg aacaatacca gatacagaaa
     7141 atttaattca gtttgctaag ttatttgatt tatcactaga caatattttg ttaggagaag
     7201 aaaaaattat ggtaaaaaat catacaaaaa cactaatact attatttcat tttgtaattt
     7261 ttttaagttt agttttcacc ttaattcagt ccggattctt ttattttagc cattcaattg
     7321 ccacttggtt attaatattt tttctaagtt tactattaat aattaatact ttaattatta
     7381 tctttaataa acatagaaac ttatttcttc acagcatatt tccaattgtt ttattaattt
     7441 ttctatactt tatataaaaa gatagaacta tttagtaaga taaaaaagta gctaattgta
     7501 attttcgtct aaaactcaaa actagtaaaa ataactttat tgtgttattt ttatttataa
     7561 attatgaaaa aggacctttc gaaatgaaaa ataatagaat ctacaaaaat cagttgaatt
     7621 atgggctttt attgccagtt tttctgctat gtatcattgg attactttct ttatatgttg
     7681 ctttatatca cgactcttac actaattcaa aaatcacaaa agaattaatt aaacaagtat
     7741 tgtggtatag tattgggttc acttcagcaa taactattta tttttttaat cctaaaattt
     7801 tgtggaaatt aactcctata ttttacggat tatgcatcat aatgttatta cttctcttga
     7861 aattctataa tccacaatta gcagtcttaa ctggagcaaa aaattggttt tatattgctg
     7921 gtttttcgtt tcaacctact gagttagtca aaataggata cacccttatg ctagctaaaa
     7981 taaccgtcaa ttatcagcaa aaatctatta ctagtaatac gaaagatgat tggatttatt
     8041 tacttaaaac ttttattgct actcttccaa taggaatatt attatttttt cagaacgatc
     8101 taggaacaat gttagtcttc attgttattt atatttttat tttgtttacg tctaacataa
     8161 atataaaaat aattgcccca ataatcgcca ttggtgttgt tttatcctta atatttttat
     8221 atttggttat atcagataca ggaagagatt tcttattaaa aataggattt cacgactatc
     8281 agtttaaaag aatagactca tggttgaatc catttttaga tccaaatgga tctagctatc
     8341 agttagcaaa tagtttaatt gctattggct ctggcggact tttaggtact ggttttaatg
     8401 tatcaaacat tcacgttcct gttagagaat ccgatatgat attttctgta attggagaaa
     8461 attttggctt tataggaagt tgtcttgtaa tattcctata cttttattta atttatcaaa
     8521 tgtataaaac atgttttaaa agcaataact tatttttcac ctatatcggt ataggcattg
     8581 ttgcaatgat tttttttcat gtttttgaaa atataggtgc aagtatcgga ttactacctc
     8641 taactggtat tccactcccc tatattagtc aaggtggttc tgccattctt agtaattttt
     8701 tggggttggg atttatgttg tgttgtagta gatatactaa cgaaaaaaaa ggaacacaaa
     8761 aatgaattca aaataacact ttatgaatag aatgtctatt tcaataaaaa ttatgatacc
     8821 ttaaagttaa tcagtgaact actcaccact tagctaaacc tgacggttct taacgcttga
     8881 agtgggagct tcttgggaat agagcatact tgatagcgta tttctttact aacagcggtg
     8941 tctcttattt accaagctat ccccgtagtt cctacggttc ttgatgattg gatctaagcc
     9001 aatcccatag aatgtagtct tagaccttcg gtcagaatat tgatactagc attgatatca
     9061 cgatcatgat gagtatgaca aacaggacaa gtccattctc gaatttcaag agatttcttg
     9121 ccatctttat gtccgcactc tgaacaaatc tgactagacg gaaaccattt atctactttg
     9181 atgatttttc gtccatacca gtcagccttg tattgtaatt tagtcacaaa ctttgaccaa
     9241 gaaacatcag aaatactttt agctaattta tgatttcgca acataccttt tgtgtttaag
     9301 tcttcaatac agataatatc gtgatttttg atcatttctg tactcaactt attcagaaaa
     9361 tcagtacgtt gattcattac tttttcatgc aatctagcta ctttgcgttt ttgtttttga
     9421 taatttttag cttcaaatag attggtacct ttatttttag ccaataaagc acgcctagac
     9481 aatttgcgtt gttcacgctt tagtttcttt tccattttgg acgtgaattt attattatca
     9541 attttttgtc catcagaaag aatcgcaaag tccataatac ctaagtcaat accaattgtg
     9601 gaattagttt taggtaattc gataatttct tctttacaca acaaagaaat atagtattta
     9661 ccgctagaat gacgtgatat tgtagcagat ttgataatcc cttttggttg tctatgaagc
     9721 ttaattctta ctaatgactt caatttagga actttgatga atttactatc aatcaaagca
     9781 actgtaccat tttgattatt cgttgtataa ctctgaacag gatttttctt acttttgaaa
     9841 cgtggaaatc caacggattt atcccgaaaa aaattcttgt atgctttatc taaattaagt
     9901 tgggcattgg ctaaagcaag gctatcaatt tctttcaaaa acggaaattc tttcttgtat
     9961 ttagctggtg tcggaaaagt cattttttta gaagaatcat ttttaacttc ttcatacgcc
    10021 ttttttcggt catcaagcat tagattgtag accttacgga cacaaccaaa agatttggca
    10081 aagaagattt cttgttcctc tgttggatag attctgaatt tgtatgcttt tagttgttcc
    10141 ataaagttca cctactttct atttatgatt gtttccttga ttttggatat acttcttaat
    10201 cacatcaatt ggtgcgccac cagttgtcag aagacaaaaa cttttagacc agaacatttc
    10261 tttccaaaga aattgtttga ctcttggaaa gtcacgtttt atcaatcttg agctggcact
    10321 tttataggca ttgatgaatt ttgtcaattc tgttttaggt tgagctttga acataatatg
    10381 aacgtggtct ttatcatgat tccactccac taaagtaatg tgatacgatt ctgaaattct
    10441 ttcaaaagta gttttggcat aatcagatat ttcatcatca atcacttgtc tacgatattt
    10501 cgttactaaa acaaggtggt aataaagaag aaatactgaa tgattatttg tatctaattc
    10561 catgttatat caactcattt cttgtataga ctgattgtaa catggaacaa aataaaaagg
    10621 caatacgcct tagttgtcgg tcttcgagtt accaacggta accctcatac cgaacggcat
    10681 tcatcaccca cctatagagg atgggcgact tctgcctaat tctgttaaaa tgttagtaaa
    10741 tattagaggt aaacaaacta tgcgtacttg ttaccttatg agttggaatg ctagtagtag
    10801 aacagccaaa tattattact acatttagta aaaacaaaac attctttcta tacaataaaa
    10861 tagcgtatag agaggatgtt tttaatttga aaaggagtgg ttatctttat gaaaaataga
    10921 tcatttgcta tattagtatt atccgtaatt ttattagata tattgttaat aacattagct
    10981 ttaaaaactt taaatttagt aacaagtttt gtcattatac cagtaattat aggaatgtct
    11041 atttatttca tcaaaaaaaa taaacaattt ttttgaatga aattacgggc gaaaataatc
    11101 actcaaaatt attaataaaa acgaatcaac tactttttct gaagaaacat acaaccgtaa
    11161 acaacaattg ttgtttacgg ttgtaaatta tcaaactata tggtgacttg ttgcttaaaa
    11221 taggttgaaa tttcgtttat tttttttgag aaattttacc cacgtactac ccatgtacct
    11281 atccacgtat tacccatgta cccccccatg acaaatgggc ggaggggctt gcggcgcttg
    11341 gtattaaagg cattatccgc ctcccaggtt tctgaccatt ttctctcata agtggggttt
    11401 ttaccgcgtt gagagaaaat ggtcagaaac ctaaacgatc ggcaaagaaa acataccaag
    11461 cgccacaagc aaaaaaagtt agagtaactt ccagaaaaga aaaattttta gaacaacttt
    11521 tgaaaatttg attttgattt atatccgttc aatttaaaca tttgataaac tgaaggctag
    11581 tatttaaaat gtgtatacaa gtggtagcgt taaaaaaagt ggaggtataa cctatgtt
//
LOCUS       DACDAF010000080        11613 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.083, whole genome shotgun sequence.
ACCESSION   DACDAF010000080 DACDAF010000000
VERSION     DACDAF010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11613
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.083"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(234..719)
                     /locus_tag="IVZ69_002131"
     CDS             complement(234..719)
                     /locus_tag="IVZ69_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HAP8184199.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     gene            1199..1840
                     /locus_tag="IVZ69_002132"
     CDS             1199..1840
                     /locus_tag="IVZ69_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP8184200.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1859..2494
                     /locus_tag="IVZ69_002133"
     CDS             1859..2494
                     /locus_tag="IVZ69_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP8184201.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2512..3327
                     /locus_tag="IVZ69_002134"
     CDS             2512..3327
                     /locus_tag="IVZ69_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP8184202.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3646..5082
                     /locus_tag="IVZ69_002135"
     CDS             3646..5082
                     /locus_tag="IVZ69_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP8184203.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5271..7718
                     /locus_tag="IVZ69_002136"
     CDS             5271..7718
                     /locus_tag="IVZ69_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP8184204.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7948..9015
                     /gene="rlmN"
                     /locus_tag="IVZ69_002137"
     CDS             7948..9015
                     /gene="rlmN"
                     /locus_tag="IVZ69_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAP8184205.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9208..10311)
                     /locus_tag="IVZ69_002138"
     CDS             complement(9208..10311)
                     /locus_tag="IVZ69_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP8184206.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            10864..11412
                     /gene="aac(6')"
                     /locus_tag="IVZ69_002139"
     CDS             10864..11412
                     /gene="aac(6')"
                     /locus_tag="IVZ69_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP8184207.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         3858 a         1956 c         2503 g         3296 t
ORIGIN      
        1 aaaagaataa aattccgatt tataatcgaa aaaagaagca tttttatata tgcttctttt
       61 ttcgtagaat caataaatat ggatttggct aactatggaa gaatactcgt attagttttc
      121 agcgttcata ctagttgtta cattgtttga ttggccaaaa gaatttctga tatattttgt
      181 gctaaataaa gaaaaagacg cttgaattgg gaaataagaa aactactcta tcattacaaa
      241 ttttcataaa ctggcagatg ttctaagtaa acaagtatct tttcaaagtc ggaaaaatcc
      301 ataatcaacg tagtggtatt gatatttgga tgaaagccta cggtatcttg acgatcaata
      361 gcagcatcga tcacgacttg gatttttttc tctttgtcgt gcatcaatgc taatggagtc
      421 actgtacctg ctggaacgcc taggaggtca ggaagctgtt cttcagaaac aaaagataag
      481 cgcttttctt ttaattgttc agctagttgt tttaaatcgg cgtgcttttc atcaggcaag
      541 atgacaagat agatttgttt tccttttctt gatttcaata atagattttt tacttgcgga
      601 ccaggtaggg aaaaagggac atttttgact gacgtaatcg caggatgatc gactttttga
      661 aaagagatac ccagtttttt tagtagttca taagcttctt gttcggttgc acgactcatc
      721 gcgcatcacc ctcctttttt tattagtgta tcataaaaaa gagttgacaa atgaaaaata
      781 atcatgtaaa ttacacgtaa agttaaaaca aatgacatcg aaaagaagag tagccgttag
      841 gtgtttttag agagtctctg gttggtggaa agaggcagca gttaaccgtg aaacacatct
      901 tggagtcgat tttctgaagc gtatagtagg aaaatccggg gagcccgtta cagctgcggt
      961 cgttgctaga tgaccagata aggctggctt ttccgtgagg agtcggtaaa aaaaggtgga
     1021 accacgtgat taacgtcctt tgatcttcgg atcaaaggac tttttgtttt catctgaacg
     1081 gcaacgactg tgtgaggttt tttctgcaag gaaaaaataa acagaggtgg aaccacgtat
     1141 aatacgtcct cttggcattt gccaagagga tttttttatt ttaaaggagg aaaagaagat
     1201 ggagtatttg attgaagtta tgccgcaatt attagtagga gcactcacaa cattgaaatt
     1261 atttttattt accttgattg gctcattacc attagggatt gttttagcat taggattgtc
     1321 tttgcatttt aagccgctac gctacttgct tcaaacatat gtatgggtta tgcggggaac
     1381 accgctgttg ttgcaactga tttttatttt ttatgggttg ccgacgattg ggatcgtttt
     1441 tgatcgtttc gaagcagcac tcattgcctt tatcttaaac tatgcagctt attttgcaga
     1501 gatctttcgt ggagggatac aatcgattcc tcaaggtcaa tatgaagcag cgcaagtttt
     1561 gcaattaagt ccctttcaaa cggtgacgaa aatcgtcatc ccacaagtga caaagattgt
     1621 tttaccttct gtagggaatg aagttatcaa cttggtcaaa gattcttcct tgatctatat
     1681 attaggttta ggtgacgtaa tgcgtgctgg gaaaatcgcg atggaacgcg acgcgacttt
     1741 actgcctttg ctaggcgtgg caatcatcta tcttacattg actggtattc taacaatcgt
     1801 aatgaaacaa gttgaaggaa aattaaatta ttaccgctaa ctgataggag gaagaaatat
     1861 gattgaattg aagaaagtga acaaagcatt tggtgaaaaa aaaataatca aagatttgaa
     1921 tctaatcatt ccagatggga aaacattagc tatcgtaggt ccttccggtg gcggtaaaac
     1981 cacgctttta cgtatcttgg ctggcttaga aagttctgac agcggagaat tttatttaga
     2041 cggtgtaccg ttcaacccat tcgagcttaa aatgaaagaa caagttgtag gagtcgtatt
     2101 ccaagacttc cagctatttc cacatctgaa tatttttgaa aacattacct tagcaccaaa
     2161 aatggtattg aaacagacaa aagaagaata caccaaaaaa gcagaagaat tagcggcttc
     2221 attagggatt agtgatttat tgaatatcta tccttatcag ctttctggcg gacaaaaaca
     2281 gcgggtagcg attgccagag cattggctat gaatccacgg gtattggctt atgatgaacc
     2341 aacaagtgct ttagatcctg aattacgcca gcaagtcgag cgtttgatcc tatcattgaa
     2401 agaagatggg gtaacccaaa ttattgtcac ccatgattta gtatttgcag aaaatgtcgg
     2461 tgatcaatta ctaaaagttt ccccaattca ttaagaaagg agaagataga gatgaaaaaa
     2521 accagttttc tattcgcttt gatcgcaggt cttcttcttt ttgcaggctg ttcgaacaaa
     2581 aaaacttcag cagataattg ggcgactatc aacgaagaga aaaaaatcgt tataggttta
     2641 gacgatacat ttgttcctat gggatttaga gataaagacg ggaagctcac aggatttgat
     2701 attgatttag ccaaagcagt ctttgaacaa tatgggatta cggtagactt tcagcccatt
     2761 gactggtcaa tgaaggaatt tgaactgaac aatggaacga tcgatttgat atggaacggc
     2821 tattccaaaa cgccggcaag agaaaagaaa gtgcaattta caaaacctta tatggaaaac
     2881 gatcaagtgc tgatcacacc taaagaatca ggaatcacaa actttggaca aatgaataat
     2941 aagagattag gtgcgcaaaa tgggtcatct ggttatgatg tatttacgaa acaaccagaa
     3001 gtattaaaag agatagtcaa aaaccaagat gctgttttgt atgatagttt taatgaagca
     3061 ttgatcgatc tgaaaagcag acgggtcgat ggtctgctga tggataaagt atacgcagac
     3121 tattatttga aacaaagaaa cgaactagaa gacttcaaca taacaaaagg ttcttatgag
     3181 agtgaggatt ttgcagttgg tgcacgcaag tcagatagta cattagtgaa aaaaatcaat
     3241 gaagccctag atcaactaga gaaaacaggt gaattccaaa aaatatccga taaatggttt
     3301 ggcgaagatg ttacgccgag aaattaacaa ataggggact gtgacaaaag acgtgtcaca
     3361 gtcccttttt ccgaataaac agtgttctcc tgccaactcc ttgtgactcg gagctgaatg
     3421 gcaggctcac aacctcttgg taaacggtgt tcaaaagcca gtttttcggt attaagccaa
     3481 atttatgcaa aaatgtagaa agccattttc acaaaatttt tcttactact cgaaactaag
     3541 cgactttttc acaacctcct ttacatattt ttattttgtt gtggaagggg tttcgtgtta
     3601 ttctaaaaga ggaacgattg aaggttatag gaaaggaaga gatgaatgga acacaaagaa
     3661 cttacctcat ttccaaaaga ttttctgtgg ggctctgctt ctgcagcgta tcaagtagaa
     3721 ggagcttggc aagaagatgg gaaaggagaa tcagtctggg atcgatttgt acggatacct
     3781 ggaaagacat ttaaaggaac gaacggtgat ttggcagtag accactatca tcgttataaa
     3841 gaagatattg ctttaatgaa agaacaaggt ctgaaagctt accgcttctc tgtagcttgg
     3901 acacggattt ttcctaatgg acgaggagaa gtcaatcaag ctgggctcgc tttttatgag
     3961 agattgatcg acgaattgat tgaaaacgat attgaaccta tgttgacttt atatcattgg
     4021 gatcttccac aagcattgca agatgaatat aatggttggg aatcacgtca gatcattgaa
     4081 gatttcactc attatgcaga aacattattt gaggcattcc gcgggaaagt ccattactgg
     4141 attagtttga atgaacaaaa tatcttcact tcattaggtt atttgttagc agcacatccg
     4201 ccaggtgtga cagacccgaa acgaatgtat gaagttaacc atattgctaa tttagcaaat
     4261 gcatctgtca tcaataaatt tcacgagtta gaaatgcctg gaaaaatcgg accaagcttt
     4321 gcgtatacgc caaattatcc aattgacagt aatcctgaaa atgttctggc tgctgaaaat
     4381 gcagaagacc tgatggccaa ttattggatg gatgtctata tgtggggaaa atatccgatt
     4441 gctgccatga ggttcttaga agaaaaagga tgggcaccaa cgattgaagc tggcgatgca
     4501 gaattgctag aatctgctaa accagatttt cttgggatca attactatca aacggcgacg
     4561 aatgcattca atccattaaa cggagttggt gctggaaaaa tgaatacgac aggaaaaaaa
     4621 ggttcatcag aagaaactgg agttcctgga atgtataaaa aagttgagaa tccatttgtc
     4681 gaacgaacaa attgggactg ggagattgac ccagaaggat taaggatcgg actgcgtcgt
     4741 atcacaagcc gttaccgcat gccggtactg attacggaaa atggcttagg agagtatgac
     4801 aagttgacag aagataaaca aatccatgac gactatcgaa tcaattactt acaaagccac
     4861 gtcaaagcca tcaaagaagc aatttcggat ggagcagaag tcctaggcta ttgcacctgg
     4921 tcttatacag atttgcttag ctggctgaac ggttatcaaa agcgatatgg atttgtatat
     4981 gttgatcaag acgaaacaca agaaggatct ttggaacgat ataagaaaga cagttattac
     5041 tggtaccaaa aactgattga agaaaatgga gagaaccttt agttcacata cttaaaacaa
     5101 gaaggtacgg ctggatatgg ccgtgccttt tcttgataaa atcatttaga aattaagaaa
     5161 aactgtaaaa taagctgaaa aatgaaagaa agcgtcagtt ctttcaaaca aaactttagt
     5221 tcccttactt ttttttgtat aatgaaactt gatgaaatga gggataataa atggcacaaa
     5281 agaaacggcc tactaaaaaa aggaaaaaga cgaaaaaaac gaaaaagcaa aaacagcagc
     5341 aggaacaaat gctgacgatt ggtgttgggt ttgccttgat tttatttgct gtcttcggct
     5401 ttttaaaatt aggtttttta ggaatattga ttgcaaacgg ctttcggatc attgcaggaa
     5461 atacttacca aatcctctgt cttttattag ccgtattagg attttggatt gtcattaaga
     5521 atacagagtt ttcaattggt aaaaaccgac gctggtttgg cggcatactc ttttatttcg
     5581 gtatcttatt attgttacat gcccatttat ttggcaaact ccatactggg gaaccaaata
     5641 tcatggggac gacatgggat ttgttagcca gtgatataaa acaaagtcaa gtagacaata
     5701 acgttggtgg tgggatgatt ggagcaatcc tttatcattt tacttacttc ttgattgcac
     5761 agcctggaag ttatttagca gcagtgctat tactggcagg aggagcattc ctgttcagta
     5821 atctggaagg ctatcagctg ttaaatggta tccaatcaat tggagaacga gtacaggaat
     5881 tattggaagg tgatcctgcc aagcaagctc gaaagcaagc ggcaaaggaa gagagaatga
     5941 aacagcgcgc agaagcgaaa gaagcaaggc gcttagctgc aaaagaagct gcagaaaaag
     6001 aagctgcaga atatgagaag aaaaaagcgg tgagccagca aagggaaaat actgctgatg
     6061 aatggcagga accagaaaat acagagccgg agcagctaag ttttgttcca atcgacagtt
     6121 ttcaagaaaa tatccatcct gcgaatctag agaaaccagt accagataca ccaaaacaga
     6181 ccaatacagc agaaggtttt tcagatgagt tgccagagga tgacggtacc tcattagaat
     6241 ttgagattga agcagaacag gaaaatcaag actatgaatt accgacagtt gatttgcttg
     6301 attctatacc aactgtggat caaagtgatg agtataaaaa aattgaaaaa aatatcggcg
     6361 tattagaaca aactttccaa agtttcggtg tcgatgccaa ggtcgtcaaa gccagcttag
     6421 gaccatccgt cacaaaattc gaagtccagc cggctgtagg ggtaaaagta agtaaaattg
     6481 tgaacttaac agatgatatc gcgcttgctt tagcggcgaa agatgtccgg atggaagcac
     6541 cgattccagg taaatcactg attggtattg aagtaccaaa tggaaagatc agtatggttt
     6601 cctttagaga aatcatcgaa gcacaaccaa accacccaga taaattacta gaagtacctt
     6661 taggacgtga tgtttctgga cgggtacaaa cggctgatct ttcgaagatg cctcacttac
     6721 tcgtggctgg ttcgactggt agtgggaagt cagtagcaat taatgggatt atcacaagta
     6781 tattaatgcg tgctaagccc catgaagtaa aactgatgat gatcgatccg aaaatggttg
     6841 aattgaatat gtacaacggc atacctcatc tgttgacgcc ggtcgtgacg aaccctagaa
     6901 aagcagcgca agccttacaa aaagtagtac aagaaatgga agaacgatat gaaaaattcg
     6961 cggcaaccgg agtaagaaat atttctggtt acaatgaatt tgttcaacag aaaaacttgg
     7021 aaaacggaac gaaacatcca accttaccat tcatcgtagt gatcgtagat gaattagctg
     7081 atttgatgat ggtagccagc aatgaagttg aagatgcgat tattcgttta gcgcaaatgg
     7141 ctcgggcagc ggggattcat atgatcctag ctactcaacg tccaagtgtg gatgttatca
     7201 caggaatcat caaagcaaat gtaccttcca gaatggcatt tgcggtatca agcggtacag
     7261 attctcggac gatcattgat tctaatgggg cagaaaagct cttagggcga ggagatatgc
     7321 tattcttgcc aatgggtgag aataaaccga tccgtgtgca aggagcattc atttctgacc
     7381 acgaagtaga acgggtcgtt caatttgtta cagatcagca agaagctcat tatgaagaga
     7441 aaatgatgcc gacagatgaa gttgaaacga caggtgctcc agaacagcca caagatgagc
     7501 tgtttgaaga agcaaaagca cttgtcgttg aaatgcaaac ggcaagtatt tcccttctcc
     7561 aaagaagatt tcggatcggt tacaaccgag cagcacgttt agtagatgaa ctggaagctc
     7621 atggagttgt tggcccgtca gaaggaagca agcctcggaa agtattcatt gagcaggaag
     7681 aaacatcaga aacgttgccg gacgataatg acatgtaaaa cttgtgtgat gaagggttga
     7741 aaaacgaata accaataaaa agacaaggca tgatgatacc aaaagaaaaa atggtttttt
     7801 tccatctttt ctaatacggt atgatgtctt gtctttttag tttttgtgag attaaagttc
     7861 tattcgattt atttgtgaag tattgcatta aggaaatgaa tcatgtatag tatgtagcga
     7921 aactttgaga aaaagaggga aaatactttg gaaaaacagt ccatttatgg cttgacgaat
     7981 gaagaattaa tcaattggtt tatagaaaac ggcgagaaaa aattccgagc tgcccaagtt
     8041 tgggaatggt tgtatcaaaa acgtgtaagt aatttcacag aaatgacgaa tctatcgaaa
     8101 caattgatcg aaaaattatc ggagcatttt atcatcaatc ctctaaaaca gatggtcgtc
     8161 caagaagctt cggatggtac agtaaaatat ttgtttgaac tccctgataa aaacatgatt
     8221 gagactgtac tgatgagaca agaatatggc ttgtcagttt gtgtgacgac acaagtagga
     8281 tgtaatatcg gctgtacgtt ttgtgcaagc gggctgctca aaaagaaccg tgatctgact
     8341 gctggagaaa ttgttgcaca gatcatgatg gtccaacatt attttgatga gcgcaatctt
     8401 ggcgaacgcg tttcacatgt cgttgtaatg gggatcggtg agccatttga taattacgac
     8461 aatgtaatgg actttttgca tatcatcaat gatgccaaag gattggcaat tggtgctcgg
     8521 cacattacag tttccactag tggattagca cacaaaatca aggaattcgc taataacggc
     8581 ttgcaagtca atctggctat ttccttgcac gcgccgaata atgaggtgcg aacatcgatc
     8641 atgcggatca accgaagttt cccaattgag aaattgatgg aagctgtgga tgagtattta
     8701 gagaaaacaa accgtcgaat cacgtttgaa tatatcatgt tgaatcaagt aaatgataga
     8761 ccagagcatg cgcaacaatt agcagatcta ttaaaagata agaaaaaatt agcatatgtc
     8821 aacttgattc catataatcc agtcagtgaa catgatcaat attctcgcag tccaaaagct
     8881 gatgtattga gattttatga tgtattgaag aaaaacggcg taaactgtgt gatacgtaaa
     8941 gaacatggta cagatattga tgcagcttgc ggacaattgc gaagcaagca aatgaaaaaa
     9001 acagttgcca aataatcgta tcctactcgt tttttcaatt accataaaag gagcagtttt
     9061 cttaattaag gaactgttca acttaaataa gagaaaagat tctatagcga aagctataaa
     9121 gctttttttg acaagaaaaa ccctcatcaa gcaaagaaat gtcctcaatt tgatgacagc
     9181 ctgcttgatg ggggttttag caattattta actgattttc ttatatcctt gctggctttc
     9241 ttgtgtagca tgataagttt ctacgtcaag aatggcctgt ttaaattttt ctcgggtgat
     9301 ttcataaggc acatgtttaa tatcatttgt tgccatggct ttatctaaga ttgcttctaa
     9361 atcggtcgtg acattgagat tcatgtcggt taacgatact ggaagttggt tctttttcat
     9421 aaacacatag attttatcaa acaaatcgaa ctgctgatcc atcatcaata aggtcagtac
     9481 accataactg acagatgctc cgtgaaggta tccctccatt ttttctagaa cagtcgtacc
     9541 gtaatagaat gagtgtgcca tagcagaatt atagttattg ttaactaaaa cagaaaccaa
     9601 tccggtagta acaatgatat ccgaaacgac ttgttcaatt gcatatgagg gacgatcgtc
     9661 ggcactatct ttcaatgctt gcgtaccata agtcaagaga cgatcaatgc acatttttcc
     9721 gatttggatt cctaatctat ccgtgtagcc tagatcatcg ccacgagcag aaaaagtaga
     9781 ttcgacttct ttggataaag catcgccaat acctgcccat aagtatttat caggtgcttc
     9841 ggcaataatt gctgtatcaa tgaaggtgtg tacaggtggt tttgaaggaa agaagagtcc
     9901 gtccattacg ccttcttcgt tatagatgac acataccgca gtgacgggcg aacagttcga
     9961 accaatagtg ggaaaggtga agactggttt agctagtttt tcaccaatga cttttacagt
    10021 atcgcaagca cggccaccac cgactgcaaa caggacgtct gctttttgga cactttcatg
    10081 ctggatcaac tgttcaatat ttccataagt tgaattaccc ccgtaccaga gactggcgac
    10141 aacctctatt tcctgtgtca aagctacttt tattttgttt tctgcctttg aaagtgcagt
    10201 cttccctcca atcagcacta cttttgtccc atattctttg acgattccat ttgctttttc
    10261 atacgcatct gttccaatgg tataatttgg taagaaaaca ctttgactca tattcatttc
    10321 cttctttctt cgttgaaacg ggttaaaatt ttaaagagtg atcgatctga ctgcggctgt
    10381 agatggagta gaggtgaacc taagacagga taagtgatga ataaggtggc atgaacacct
    10441 tgaaatcatc aataagtatc ctaaaaacga acaagtacaa aaacattgaa aacgacaata
    10501 atgaattttt gttcctctta gtatttctac cgattccctt tgcttttttg taattatcta
    10561 aaaattctaa aaattaagat tattatatga aaacaggttt tatttgtcaa ttcataattg
    10621 gtttttttta aagcaaaaga taatctatat catgatgaac aaacagagtt ttttcctcca
    10681 attgatggct ttcctgatct ttcctatttt gaataaagtg tttctgtata atttttttat
    10741 tttataagta agataaataa tgaaagaata gagatactga ttggtagcta aagatttttg
    10801 agcgagaaca tttcgttttt tcaaaaggac tgttagaata agcaagaaca agggggaaga
    10861 cgtatgataa tcagtgaatt tgaccgtaat aatccagtat tgaaagatca gctttctgat
    10921 ttactgagac tgacttggcc ggaagaatat ggagacagct cggcagaaga agtagaagaa
    10981 atgatgaatc cagaacgaat cgcggtagca gcggtagacc aagatgagtt agtaggattt
    11041 attggtgcaa tccctcaata cggtatcaca ggttgggaat tgcatccatt agttgtagaa
    11101 agctcccgac gaaagaacca aataggtact cgattagtca attacttaga aaaagaagta
    11161 gcttccagag gaggaatcac gatttattta ggtacggatg atttagacca tggaacaacg
    11221 ttaagtcaaa cggacctgta tgagcataca tttgataaag tggcttccat ccagaacctt
    11281 cgtgaacatc cgtatgaatt ctatgaaaaa ttaggttata aaatcgtagg tgtcttacca
    11341 aatgcaaatg gctgggacaa accggatatt tggatggcaa aaacgattat tcctcgacca
    11401 aattctcaat aataaaaaga ggttgtgaca gaagtaatca gcttcaagaa ataagaagga
    11461 atttacgaaa attacttctt gaatttttgt gaaattccaa cttatttccg aagaagctac
    11521 ttttggaaca ccgtgtacca gaggttgtga aaaagtcgct tagtttcgag tagtaagaaa
    11581 aattttgtga aaatggcttt ctacattttt gca
//
LOCUS       DACDAF010000081        11600 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.084, whole genome shotgun sequence.
ACCESSION   DACDAF010000081 DACDAF010000000
VERSION     DACDAF010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.084"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            79..852
                     /gene="sufC"
                     /locus_tag="IVZ69_002140"
     CDS             79..852
                     /gene="sufC"
                     /locus_tag="IVZ69_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HAP8184208.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            865..2151
                     /gene="sufD"
                     /locus_tag="IVZ69_002141"
     CDS             865..2151
                     /gene="sufD"
                     /locus_tag="IVZ69_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HAP8184209.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            2148..3383
                     /locus_tag="IVZ69_002142"
     CDS             2148..3383
                     /locus_tag="IVZ69_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HAP8184210.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            3370..3840
                     /locus_tag="IVZ69_002143"
     CDS             3370..3840
                     /locus_tag="IVZ69_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HAP8184211.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            3845..5236
                     /gene="sufB"
                     /locus_tag="IVZ69_002144"
     CDS             3845..5236
                     /gene="sufB"
                     /locus_tag="IVZ69_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HAP8184212.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(5331..6473)
                     /locus_tag="IVZ69_002145"
     CDS             complement(5331..6473)
                     /locus_tag="IVZ69_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8184213.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(6512..7246)
                     /locus_tag="IVZ69_002146"
     CDS             complement(6512..7246)
                     /locus_tag="IVZ69_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184214.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            7478..7753
                     /locus_tag="IVZ69_002147"
     CDS             7478..7753
                     /locus_tag="IVZ69_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8184215.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            7851..9848
                     /locus_tag="IVZ69_002148"
     CDS             7851..9848
                     /locus_tag="IVZ69_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184216.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKIHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVGDNSVKNALIKNRGYFVKQGFTLERASKDIKKLYNVKASSSFLIYLAKGAGI
                     DETIKELILSGAGIVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(9924..10259)
                     /locus_tag="IVZ69_002149"
     CDS             complement(9924..10259)
                     /locus_tag="IVZ69_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184217.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            10386..10601
                     /locus_tag="IVZ69_002150"
     CDS             10386..10601
                     /locus_tag="IVZ69_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184218.1"
                     /translation="MKKVNNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPMNELFSDVFNKVNS"
     gene            10638..11000
                     /locus_tag="IVZ69_002151"
     CDS             10638..11000
                     /locus_tag="IVZ69_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HAP8184219.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEKMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            11046..11372
                     /locus_tag="IVZ69_002152"
     CDS             11046..11372
                     /locus_tag="IVZ69_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184220.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
BASE COUNT         3853 a         1959 c         2354 g         3434 t
ORIGIN      
        1 agtaaggaag gtcattgcgc ttcattctca attagtctaa aatgagtgag aacgaaagag
       61 aatttggggg tataatgcat gtctgtctta gaaataaaaa atctacatgt gtcgatcgag
      121 gaaaaagaaa tccttaaagg cgtaaaccta acaatgaaaa ccggagaaat ccatgccatc
      181 atgggaccta acggcacagg aaaatctacc ttatctgccg ctatcatggg caatccaaac
      241 tatgaagtaa cagaaggcga aattttgttt gacgggaaaa atgttttaga cttggaagta
      301 gatgaacgtg cgcgacttgg cttattttta gctatgcaat atccaagtga gataccaggt
      361 atcacgaatg cggaattcat gcgtgcagcg atcaatgcga aacgtgatga aaacgacaaa
      421 atttctgtta tggcattttt gaaaaagtta gatgaaaaaa tggctttact aaatatgcca
      481 gaagaaatgg ctgaacgtta tctgaacgaa ggtttttctg gcggagaaaa gaaacggaat
      541 gagatcctgc aattgttgat gttagaacct acatttgcaa ttttagacga aatcgattca
      601 ggtctggata tcgatgcttt gaaagtcgtt gctaaaggag taaatgaaat gcgcggagac
      661 aatttcggtg cattgatcat cacccactat caacgattat tgaactatat cacacctgat
      721 gtcgttcaca tcatgatgga aggccgagta gtcatgacag ggaatgctga cctagctaaa
      781 cgtctggaag cagaaggcta cgctggtatc agtaaagaat taggaatcga ctataaagaa
      841 gaagaagcgt aagggggagc aagaatgaaa gaaaaaaact ggctcgatta tcttgacgcg
      901 gtaaatgatt tttctttaag taaaggcgaa cctgattgga tgagaacctt ccgtcaagac
      961 gcactagcga aagcagatga actgccattg ccgcatatcg atcgggtgaa attccatcgc
     1021 tggtcgttat ttgatgtgaa agaaacacaa accatcagtg aaacaggcac gattccggca
     1081 tttgatgcaa tgaaagacaa tcctgtgctt gtccaacaag gttcatggac gatttttgaa
     1141 caactgcctg tggaattagc agaaaaagga gtcattttta ccgacttgtt cactgcaatg
     1201 atcgaatatc cagaactagt ccaagaatat tatatgaaaa aagcagtaaa catgaacgaa
     1261 gaccaattga ctgcactcca tgtagctttt atgaacagcg gtattttcct gtatgtgcct
     1321 aaaaatgtcg tgatcgatga accactcgag tccttattca ttcaagatgg cgcatccgat
     1381 gagcacttct tcaagcatgt gttgatcgtg gcagatgaac atagtgaatt ttcttatctg
     1441 gaacgtttcc agacaaccaa agaacaagta gcaaaatcat caggtaatat catcgtggaa
     1501 gtcatcgcta aagctggttc aaaaatcaaa tattcagccg tagatcaatt aggagaaaat
     1561 attacttctt atatgaatcg ccgtgggcac attttacgag atgcttctgt cgactgggca
     1621 attggtgtca tgaatgacgg tcatgtgatc gctgactttg actcagattt agcaggagaa
     1681 ggtgcacacg cagaagtcaa aatcgtggca atcagctcgg gcagacaaat ccaaggaatc
     1741 gatacacgag taaccaataa agcccctcat acgatcgggc atattttgca acacggagtg
     1801 atccgagaaa aaggaacatt gacctttaat ggtatcggcc acatcttgaa aggggcaaaa
     1861 ggtgcagatg cccaacaaga aagtcgtgtc ttgatgcttt ctgataaagc acgtggtgat
     1921 gcgaatccta ttcttttgat cgatgaaaac gaagtaactg ctggacatgc tgccagtgta
     1981 ggacgagttg atccagaaga aatgtactat ctgatgagta gaggattgca taaagaagaa
     2041 gcagagcgct tagtgattcg aggattcctc ggttctgtct taacagcaat ccctgtagaa
     2101 caagttcgga aagaattagt cgaagtaatc gaagggaagt tgaatggatg atcgatgcta
     2161 aaaagctacg caatgatttt cctatcttat ttcaagacgt caatgatgaa cctttagttt
     2221 atctggataa tgcagcgacg acccaaaagc caaaacaagt actccaggca ttagcgtact
     2281 attacgaaca cgataacgcc aatgttcatc gcggtgtcca tacgttagca gaacgcgcga
     2341 cccatgatta tgaacaagca agagaaaaag tacgggcgtt catccatgca aaagaaacag
     2401 cagaagtgct gtttactcgt ggtacgacga caagcttgaa ttgggtagcc agaaccttcg
     2461 gcgaccgcta tatcaaagca ggagacgaga tagtgctctc ttacatggaa catcattcta
     2521 atgttatccc gtggcagcag ttggcaaaac gaacaggtgc tgtcttgaaa tatatcgaac
     2581 taacagaaga aggcttcctg gatatggagg atgcagcgaa aaagattacg gacaaaacca
     2641 aaatcgtctc cattgctcat gtatccaatg tcttaggtgt cttcaatcct gttcaagaat
     2701 tagctgaact tgtccatgaa aacggcgggg tcatcgtagt agatggtgct caatctgccc
     2761 cgcacatggc cattgatgtc caagcactag actgtgattt ctttgctttc agcggacaca
     2821 aaatgtgcgg accaacaggt attggtgttt tatatggtaa acgaaaatgg ttagaagaaa
     2881 tggaacctgt tgaatttggt ggcgaaatga tcgattttgt cgaattatac gacagtacat
     2941 ggaaagaact accttggaaa ttcgaagcag ggacaccaaa tatcgccggc gctatcgcat
     3001 taggccatgc aatcgattat ttgcaaaaac tcggtatgga caatatccat cgatatgaag
     3061 aagaactagc cgcttatgtg ttgccaaaat tacaagcaat tgatggattg actgtttatg
     3121 gtccacaaga cccgaatttt cggacaggag tcgttgcatt caatttggat gggttacatc
     3181 cccatgatgt cgcgacagct ttagacatgg aaggggtagc cgtcagagca ggtcatcatt
     3241 gtgcgcaacc gctattgaag taccttgaag tatcagcgac tgctcgcgcg agcttttatt
     3301 tctacaacac aacgcaagac gccgaccgtt tagttgaagc aatcatggca acaaaggagt
     3361 ttttccaaca tgggactatc taaattagac aatttatacc gtcaagtgat cttggatcat
     3421 tcttcccatc cgcatcatcg tggaagcttg actgactcga caagcaagat cgaattgaac
     3481 aaccccacat gtggagatgt gatcgaattg caagtcgatg taaaagacgg aatcatcaaa
     3541 aatatcgcct ttgacggcag tggctgctcc atcagtacgg caagtgcctc gatgatgaca
     3601 gacgccgtca tcggaaaatc aatagaagaa gcagaacatt taactgtaga ctttctacag
     3661 cttgtccaag gaaaagaagt caaagatccc gaccaattag gcgatgctgc tatgcttggt
     3721 ggtgtagcta aatttcccgc tcggatcaaa tgtgcgacac ttgcctggaa agcactagga
     3781 aaagcaatgg aaaacgatgg taccgcagct ttccatcatt accacaagga agaggagtga
     3841 gaacatgggc gtaccagaat tagaagaata taaattcggg tttcacgatg atgtcgaacc
     3901 ggttttcagt acaggagaag gcttgacaga agaagtgatc cgtgagatgt caagaatcaa
     3961 aggcgaacca gaatggatgc ttgaattccg tctgaaatct ctagaaacat ttaacaaaat
     4021 gccaatgcaa acatggggcc ccgacctttc agacatcgat ttcgatgcca tcaaatatta
     4081 ccaaaaacca agtgacaaac ccgctcgtga ctgggaagac gtaccagaaa aaatcaaaga
     4141 tacatttgaa aagattggta taccagaagc tgaacgagct tatctagccg gtgcttccgc
     4201 acaatatgaa tcagaagtcg tgtaccataa tatgaaagat gaattcgaaa agttaggaat
     4261 cgtctttact gacactgact ctgctttgaa agaataccct gaattattca aagagtactt
     4321 ttcaaaactt gtaccgccaa ccgacaacaa attagcagcg ctgaattcag ccgtatggtc
     4381 aggtgggacc tttatttacg tgccaaaagg cgtcaaagtc gatgttccat tacaaacgta
     4441 cttccggatc aatgcggaaa acacggggca attcgaacgt acgctgatca ttgttgacga
     4501 aggagcaagc atccactatg tcgaaggttg tacggcacct acttattcaa gtaacagcct
     4561 gcatgccgcc atcgtagaaa tctttacaag aaaagatgcg tattgccgtt acacaacgat
     4621 ccaaaactgg tcagacaatg tgtacaactt agtaaccaaa cgagcaaaag catacgaagg
     4681 cgcaaccgtt gaatggatcg acggaaacct aggtgcaaaa acaacgatga aatacccaag
     4741 tgtttactta gatggaaaag gtgcacgagg caccatgctc tccatcgcct ttgcaggagc
     4801 aaaccaaatc caagatacgg gtgcaaaaat gatccacaat gcaccaaata catctagctc
     4861 tatcgtctct aaatcaattt caaaagacgg cggagaagta aactatcgag gacaagtaac
     4921 ctttgccaaa aacagtgcgg gttcgatctc tcatatcgaa tgtgacacga tcatcatgga
     4981 cgaatggtcg aaatccgata cgatcccatt caatgagatc cacaacagcc aagtctcttt
     5041 agaacacgaa gccaaagtct caaaaatctc agaagaacaa ctctactatc tgatgagccg
     5101 aggcctgacc gaatctgaag caactgaaat gatcgtcatg ggctttgttg aaccattcac
     5161 caaagaactt ccaatggaat atgcagtcga actcaatcga ttgatcagtt atgagatgga
     5221 aggcagtgtt gggtaaacct gttataggag ctagaaccct tgatatataa gggttctagc
     5281 ttttttgttt tgcctgtata ctagaaatga ccagattttg accagctctt ttactgatga
     5341 gccatcatat cagcaaagtc ttgacctgtt ttcttaggtg cattatttgt aatatgtgca
     5401 tagatgtcta atgtcacttt actattttca tgccctaatc gttgttgaac taccttgaca
     5461 gattctcctg cttctaataa taaactagca tgtgtatgtc taaacccatg aggtgtaata
     5521 cgaggcaagt tatatttttt caaaatatat cttaaccaat cattaacagt gtttggaatg
     5581 tatagagtgt ttttaactgt tgtaaaaaca tgttgctctt tagagctagt attgtatcca
     5641 agttttaaat actcttcttt ttgctgtaat ttccagttgt tgaggataga aagagtctca
     5701 gtatctaaag agataactcg tctagaagct cttgttttcg gagattgaat tataacttta
     5761 ccaaattcat ctacagcaag agttttattg acatgtagtt ctttattaaa cgtgtctatg
     5821 tctttccact gtaaagcgag tacttcactc tttctcatac ctgtgtatgc caataatctg
     5881 aagaaggcgt attgtttcat gttaccaaaa tctttaaaag catccagtaa attattaagc
     5941 tcctcttttg agtaaaattt acgatttttc tcatactctt tttttcgtgg aagaagtgtt
     6001 ttttccatag gattattgtc aatatattgc attgcaaccc cgtagcgtaa aatttgtgca
     6061 gtctgttttc tcatataatc gtaactttca tatttactgt gccattcatc taccactttt
     6121 tgacaatatg ggacagagat attcgatagt ttaagcttac caaatgctgg aagtatttga
     6181 ttatttgcgt atcttactga gattgcgatt gttgaagctt taacactggt acgctgatga
     6241 gttatccatt cattatacag gtcttcaaat gtcatatcag gtgctttctt tttaacaccg
     6301 tataatattt gatgtctgta ctcgtcataa tctttttgag cttcttgttt gctactaaaa
     6361 cctcttctcg tagtatttat tttttcacca gttcgtggat cggtggcaat gtgtccttta
     6421 tacatccacg ccacttgacc gtttttcttt ttgtactttg atatttttgc cattaaatca
     6481 tctcctctta gtttacaagg agtacttacc actagatggt atcacctccc ttcatttttt
     6541 tcttagtgta ttttttccca attgatgaaa tcgtttgttc tagcttgttt atattatcag
     6601 taatttctct cacagcttct tcgggataag acatgtcttt caattgaata ggtagccatt
     6661 catctaccat tctttctagt agttcttcta tactgctagt gaggaaaaga atgttattgt
     6721 caaattcttc tacaatagca ttgatgaata attcttctat ttttaagata ttgaaaagac
     6781 taattttttc atttttaact ttattacaag tcttgttagc aataaattct tgcatctctg
     6841 gttctaattt ggaatatcta tccagccatg tatctaaatt agagtgtact ggtgggaact
     6901 gttgacgaag atgctggaac aggtttttat ctggaaatgt tataccatct agtacaatgc
     6961 tatctctata aagaataatt cccaaaatat attcttctac attgccacaa actaactcct
     7021 ctatactcat atttcccaaa tcagcaattc gggataatcg ctctggtatt ggtaaatagg
     7081 ttcccttctc ccattcgtag atagtttttt tgtcaattaa ttgaccgttg ttaatcataa
     7141 gaccaaatgc tggttgtgtt aattttttac tctttcttat agcttttatt tttgttccga
     7201 gtatcttttt tcgttctaaa taatttattg gtggacgttt tatcatattg accacacctc
     7261 ctaaaattag tatacctcaa aaaaggggtg ttgtaaataa attttacaaa gctgttgaca
     7321 cccctttttt atcgaggtat tatgtgtatg tcgatgaact ggtaatcatt ttttgtttga
     7381 ttaatcggtt aataacaaaa tacttttatt ttgagcaaaa aatacgaaga taattcttag
     7441 aaaatttgtt caagcaatca cgaaaggagg gggaaatatg tctctacaaa tcattgatag
     7501 cattgtttct atacaagttg aacaacaagt gaaagagata attacagtgc taaagcctat
     7561 gctagaagac attatttctg gagtcactct agagtatatg gactatcagc aggcaagtga
     7621 atatctaggt gtatcagtag gaacgattag aaaatatgtt tctcaatacg ggttacctgt
     7681 tataaaaatt gatacggtca ttagatttaa aaaatctgat attgatagtt tcatggaacg
     7741 gtataaaggt tgagtaaaca aataagacta aaacatatag taataaagag tttgttttta
     7801 ttatctgtat gttttagtct ttaacagaat tttataagga ggaaacacaa atggaaacat
     7861 caatgattaa tattccaatt tatgtagatc aagaaaaatt attagagaag ccagttacaa
     7921 aaaaagaaaa aactgatgta agagataggt gtttagataa ctatagagaa gttacaagag
     7981 atgagtttgt agagatacta aattcatcac aatcatttat tccaagcaag acaaagaata
     8041 aaggcaatga caaggagagt tttgtggaaa ccagagtaat tattctggat gtcgataaca
     8101 ctgttaaaga tgagaagggg aaggtagtag atttgagtaa agatgatagt agatacttaa
     8161 gcatagaaaa ggttttatct atcaatttag ttcataattc tgcgtttgcg atacaaaaaa
     8221 gtattcggta ctctgaaaat ctagaaaaat acaagattgt ctttctatta aaagaagcaa
     8281 ttactgacta tggtaaaatg gttgctgttt acgaatactt gaaaaagaac atccccgggt
     8341 gtgatgacaa tgtaaatgct tcgaatagaa tgttttttgg aggatataag tcagatgcag
     8401 tgataataat taatgaagac aacatgttag atattactga gcttccgatt gattttacca
     8461 tgacatgttc taaaaattgt caaagtgatt cagggagaga gtatgaacta gtcaatgaaa
     8521 ccgattttgt taagttgata aaaaatgacg acaaagaaga aatgaaacag tggtttaaag
     8581 actgcctgtt tgattcctcc gacatgtctt ttaatgagat ttatgaaaga ttgttaacca
     8641 ttgatatgaa taaattactt aagtcaagta aaaacttaag atgtctgttt cacaacgatc
     8701 ataatccctc tgctagtatt tttaccagta aaactgggca ttccattttt tattgtcatt
     8761 ccagtaattg tgatatcagt gaaaatttta ttggagttgt gatgctaatt ttaaagaaag
     8821 acagtcgggt agaaacattt aattggctat tagagaacct agacttgtat cctacacatt
     8881 ttcgaaaatt gaaagaggaa tcaaaagtac tttttgacac tcttgaatca atgaaagaca
     8941 aacttttcag gacaataagg aattatctag aggaaatgcg acgtgtctat gatgtcttgc
     9001 tttctgatgt taattttttt gatgatagta aggaaagtgt gacttgtatt ttgtcggggg
     9061 aacaattagc taaaaaaatg agttcttact atggtaaaac ttatgacata gataaatgta
     9121 ataagttact atcacttatg acttttatag gattgataaa aaaattagat gatgaagatg
     9181 ttcctttgaa gatgctcgaa tacctaaata ggttaaagga agagaaagcg ttaggaaact
     9241 ttaatcataa gagaagcaat gtctatcgat tagacgtttt taatgcaact tctgtgattc
     9301 aaaaattgaa tgaagatatc cttccacttc tggaaaaaat tcattttaca tatcaatatt
     9361 tttcttatga atgggttaag atatgtttta acgaaaaaga ggctaaaaga gtatttcctc
     9421 aaaattcccg atcagaactc agcaaggaaa aacaattgat tttagatgaa gcacatgaag
     9481 ttttacaggg cttatcgtgg caagggacat atctaatgac agagaaagaa cttattaaca
     9541 ctgtttgtga acgcctacgt aatgttgggg ataacagcgt gaaaaatgct ttaataaaaa
     9601 acagaggcta ctttgttaaa caaggattca ctcttgaacg agcttctaag gatattaaga
     9661 aactatacaa tgtgaaagca agtagtagtt ttttaatata tttagcgaaa ggggcaggga
     9721 tagatgaaac aataaaagaa ttgatattat caggagctgg gatagttcct ctgtatcaat
     9781 ttacaagtgt aacaagagat gatggacgga gagtaaggaa gagaaaagac ccaattgtat
     9841 taaactagac aggttatcca tagctcttaa tcttatttca tctcaataca cccaccgtta
     9901 aagttcggtg ggttatttat ttttcaatct ttcaatagct gattgcgttc attttcttgc
     9961 ctttttaata gcttcatata gtcaattgtt cgaactgcat cttcagtgct aagagaacga
    10021 tagagagcca aaaactcttc ctcataatct acgacaacat tgtctagaaa atggcttaca
    10081 ggggttccta gggctctaga aagagctgtt aagctatcga ggttaggctc tgttacagaa
    10141 ttttcccatc ttgctactgc ctgttgtgta gagaagattt tttcagctaa ttctttttgt
    10201 gtccacccga gagcttttcg cttttctcta atgacctttg catattgttt ctgtttcatt
    10261 aatacacccc catctcagta tagtacaaca agttgttgta tttgtaatgg tatttgaagt
    10321 tttttatatt ttatgagttg aaatacatca tattgttgta tataataaaa caggagggga
    10381 gaatcatgaa aaaagtaaat aatctcagcc gatacagaaa agaaaaagga ctttctcaaa
    10441 cggagttagc aaaaaaaatg aatgttacac agcaatgtgt aagttcgtgg caaacaggga
    10501 gaacgattcc taaaccctat caaatgaaga tgctttctga gatattaagt gtaccaatga
    10561 atgagctgtt ttctgatgta tttaataaag taaacagtta actaataagc aattgaatga
    10621 ttttaggagg agaagacatg tattgtagaa aatgtggcaa agaaataaca gatgaaagta
    10681 agtattgcca gttttgtgga gcactacaag aaacagatga gacaaccgga acagacacag
    10741 taaagaaaag tactgagcag acaattaatg aaatgaagga acaaatcgta catggacaag
    10801 agacagggaa gctgtatttg attattggtt ggatttctat ggtagtatcg ttagcattta
    10861 ttcctgttgt atttggtgct gttgctgtta ttatgggcta cttatatcga gaaaaagatg
    10921 agaaaatggg tacgattttg atgatagcag gggtagctgg agcaatcttt ggtgtacttt
    10981 tagggatgtc aatgtactga taagagggat aagaacaaat tattttggag ataggagata
    11041 aaaagttgaa taaagtaaat atgaacaaga agtttgtcat tataggtatt gttgtcttgg
    11101 ctattatagg tattattttt tcaaaaatga caggtacatc tggattagag aagtcatcaa
    11161 aaccattggt aacacagatt ttacaagaac agtacaactt aaatcgatca tgtgatgatg
    11221 tgacgattac tcatgaaaat ggagataaca cataccgggc taaagctata ttagacaatg
    11281 gaagtgctat caacataaat attgagtact atccaaagaa agaccgtata tatgtggaga
    11341 taccatatgc tgaggtgtta atgttaaatt gatttaaatg tattatgcat accgtccaaa
    11401 caggaactcc caaaggtgta aattcactag ggagttttta tagtttccta taaattaaat
    11461 actaatacag gtgacaaaaa aatattacaa tgattgtcgg gaatttttat gttattcact
    11521 gttataacaa tataaaagaa atgaaaaaga aaaaattatt atggatatgt ttggtatttt
    11581 tattgataat tggtggaatt
//
LOCUS       DACDAF010000082        11575 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.085, whole genome shotgun sequence.
ACCESSION   DACDAF010000082 DACDAF010000000
VERSION     DACDAF010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.085"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            51..260
                     /locus_tag="IVZ69_002153"
     CDS             51..260
                     /locus_tag="IVZ69_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184221.1"
                     /translation="MICYISFLILGLPQAVFPEMFSGDWGIVSYSILTLIAMVLGTSF
                     YNAFVSKHVEEYEVLMYLKEKKTSN"
     gene            467..667
                     /locus_tag="IVZ69_002154"
                     /pseudo
     CDS             467..667
                     /locus_tag="IVZ69_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298761.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1379..1984)
                     /locus_tag="IVZ69_002155"
     CDS             complement(1379..1984)
                     /locus_tag="IVZ69_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8184222.1"
                     /translation="MAKIGYIRVSSQDQNLDRQLAMMEDLNIDKLFQEKASGKDIQRP
                     EFQKLLNYIREGDCVIVASLDRLGRDYEDIKNTVTFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAKKAGRYKGRPIEYSENSTDPQ
                     KRLVFKTVVDMLNQGVPVAEIAKENGLSRPTIYKIKKANDL"
     gene            2166..2501
                     /locus_tag="IVZ69_002156"
                     /pseudo
     CDS             2166..2501
                     /locus_tag="IVZ69_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343406.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2666..2893
                     /locus_tag="IVZ69_002157"
                     /pseudo
     CDS             2666..2893
                     /locus_tag="IVZ69_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613886.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            3019..3990
                     /locus_tag="IVZ69_002158"
     CDS             3019..3990
                     /locus_tag="IVZ69_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8184223.1"
                     /translation="MKTTMKDVAALAGVGVGTVSRVINGVKVKEVTKEKVMAAISELN
                     YEPDEYARGMKTNSSNTIALILPTIWHPFFSEFAYYVEEALSQKNYKLFLCNANGSAE
                     KEKEYIQMVKQSKVDGIIGITYSDIDKYVSSNLPFVSIDRHFSEQVSYVTADNYLGGQ
                     IAAQELLTRNCKNLCYVGGVSPYPNETNNRKAGFYNICEENKIAVKVLDMPEPISNLE
                     EQLLAFFSDNPEIDSIFTINDFMALDVIKAQKKLGKEAPKDFQIIGFDGVKLSLQKDY
                     LLSTIVQPIEEMAKVSVETLMAMILNEEPPKRVVVPVFFHAGETTKE"
     gene            4130..5443
                     /locus_tag="IVZ69_002159"
     CDS             4130..5443
                     /locus_tag="IVZ69_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HAP8184224.1"
                     /translation="MKKRMLAIAAILALTAGGLAGCGSKEKSSGSSDPGEIKIWVQFS
                     DETPEGKAWAEIVNNFNDEYEGEYKAVTEYIPRSGSGGGYEDKVNAAITTNTLPDVIT
                     LDGPNTAAYAHSGVIAPLDDYLKDADMDDVLDSIIQQGTYDGKMYAFGFSESSVGVYY
                     NKSLFKDAGITEDQLPTLEDPWTWTEFQAICQKLTDKYKTPAIDMQMASGDEMLTYAY
                     TPFIWSNGGDVVNADGTKAEDYFNGKKSVEALEFIQELVEKGYTTISPIEKGFETGKY
                     AMMLSGSWTMADLEENYQEIDYGILPYPVSDATGELVSPTGSWQLAMTEKTEKKDASA
                     AFIKFATSTESSRIMSLGNSVLPIRNSTVDLIKDEVSEGMQVLIKQNQLSGHARPVVV
                     AYPQVSRAFQQAVQDISYFEENPDVQKVADSRAAEMQQAIDTSLK"
     gene            5486..6352
                     /locus_tag="IVZ69_002160"
     CDS             5486..6352
                     /locus_tag="IVZ69_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8184225.1"
                     /translation="MKDNLIGYGFLAPALLLLTIFLIIPVIMVIYYAFTDYYLLTPDA
                     RQFIGLENFKRLFADPIFVKSIWNTAKFVVWIIPVQIGAALGMALIINKNRKGNIFFK
                     VAFFAPVVMSLVVISILWLYLLNPNEGLVNTLFAKIGIASQPFLTSPKQAMYTLVFVS
                     AWQGAGYQMLLFLGGMQNIPQDVYEAAEIDGFSKFQQFRYITMPLLKPTAIFILLTTL
                     ISAFKLIIQPMVMTQGGPMNSTMTMVYYIYQTGFTDRMVGYSSSIALIFTTMIGLITI
                     AQRKLVKEDDPA"
     gene            6349..7197
                     /locus_tag="IVZ69_002161"
     CDS             6349..7197
                     /locus_tag="IVZ69_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006639650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8184226.1"
                     /translation="MTKKFGPLMIVEYCLLFLLAALFIFPMLWMVVSSMKPEADVYQN
                     LASFKAFLPSLNPANWFKTYQEVISRFSVGTYLLNSIFYGLTFACGSIIVNSLAGFAF
                     AKVNFSGKKIIFGALLALLIVPMETVLIPQFTIVNSLGLVNTRLAVILPAMASAFNIY
                     LFRNFFIAIPEEIIESAKLDGANIVKIFFHIMLPMSKPAIATVGVLSFISSWNDYIWP
                     LMVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTIATIPLIIVYIVAQKYILQGLGG
                     SGTGIK"
     gene            7211..8683
                     /locus_tag="IVZ69_002162"
     CDS             7211..8683
                     /locus_tag="IVZ69_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP8184227.1"
                     /translation="MLQKLLKANEFIEKNAQTVNQEYRNKFHLMAPIGWMNDPNGFVY
                     YQEEYHLFYQYYPYDSIWGPMHWGHAKSKDLIHWEHLPVALAPGESYDKEGCFSGSAI
                     EKDGKLYLIYTGHNVVEGQVRQVQCLAVSEDGIHFEKYAGNPIIAEDHLASVATTEDF
                     RDPKVFQRKEDYFTVVATKTADARGQIVMFHSKDLLTWEFYSVLLEGTPEQGIVWECP
                     DLFELDGKEVLILSPIQMTPQGNAYQNTNSTVAFIGTVDWQTGKFLVENFHEIDGGLD
                     FYAPQTCENEAGQRIMIAWMQMWQRKIPTNDLGHGWSGSMTLPRELRVADNQLLQRPV
                     SSIYQVIDPQERIEWAKTEENRFLLKDLVYDQHYLRLEINLKQATKLELHYAKGPDHT
                     LLLNYDVERECFTASREHMPYDLSGAEKEVLKKRSVTIPLENNCLTIEIFRDTSAIEL
                     FLNDRLTMSTTFYETEKGQDFLLLADSEVTFSLESGLINL"
     gene            8700..9572
                     /locus_tag="IVZ69_002163"
     CDS             8700..9572
                     /locus_tag="IVZ69_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP8184228.1"
                     /translation="MIYGSIEAGGTKFVCAISDEEMTIKERVSFPTTTPEETIPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKVAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIEKRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
     gene            complement(9808..11190)
                     /locus_tag="IVZ69_002164"
                     /pseudo
     CDS             complement(9808..11190)
                     /locus_tag="IVZ69_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010726506.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         3565 a         1999 c         2341 g         3670 t
ORIGIN      
        1 atttaaaaag aaaagtgaca gataggaata aaaacttatt aaatgtagtt atgatctgtt
       61 atatttcatt tctaatacta ggtcttccac aagcagtgtt tcctgaaatg ttttctggag
      121 actggggtat tgtcagctat tctatattaa cattgattgc tatggtttta ggtacttcat
      181 tttataatgc ttttgtaagt aagcatgttg aggaatatga agtattaatg tacttaaaag
      241 agaaaaaaac aagtaattaa tatgagaaca ccacgcatag tttttatttt gagatattct
      301 agaatgaaac acattaagaa cgaaagcaaa gcaaaagacg ccagaacttc tactaccttc
      361 taagtttttt catatttgtt tgttatgcta tacatagatc tgcataatta gacttgcgct
      421 gcccgttatt gaagtttcag gcagcgctct ttttggggga tcgataatgg aagaagaaaa
      481 aatatttgag aaacgctggc agctagcatc aagtgaacaa agagcaagat acaataattt
      541 gatcacctcc taccccactg ttgactagac atataaggaa aagaaatact tactttggct
      601 gtgccagtta gatatagata cctttgaaac atttgaagtg atcctagata aaattaaaca
      661 gaattgatca gaaacaagcg aagccttctc tcggttcgct tgttttgcta tttattagtt
      721 ggctcagggc aactctaagc tcgtttgaaa gaaaaccgat ggataatccc cttgtttgta
      781 ccactttaga atacatggat gtacgtattg ccattgactc ctattagtta ctgaaaaaaa
      841 atttaaacaa gttgagtatt gcagataaat agctccagtg aggtgaataa ctgctccact
      901 caaggcaata gatagctcca tccagggcaa caaactgctc cactttcata tttaatagat
      961 gaataacctt ctgtataata gaaaggcata cctttcggta tgacaactta tacagaatgt
     1021 tattttattg gttcactatc gaaaaatttt ggagctttat ttttccggta tttctcaacg
     1081 aacgattagt ttaactgtgg gaagctccag acatacgatt cgagaagtta cttctcgagc
     1141 agacaggaag ggggtgactg aactaaccgc tgatatgagc gatacttggc tgtaggaata
     1201 tctttttccg gaaaaacaaa caacagcacg aggttacctt cctgtagact gggaatatgt
     1261 tcataaagaa ctaatgaaaa agaatatgac attgaaactc cttcatagag aatatggggt
     1321 acatggaaca tagaaacgaa aatgcacggt agaaaagcga atgaatatag tataaattct
     1381 acaaatcatt cgctttcttt attttatata tggttggtcg agagagacca ttttctttgg
     1441 caatttctgc aactggaact ccttgattta acatgtccac cacagtttta aagactaatc
     1501 gtttttgcgg atctgttgag ttctcagaat attcaattgg tcgcccctta tatcgaccag
     1561 cttttttggc caataatact ccttgccgct gacgttcacg gattttctca cgttcgtttt
     1621 gtgcaatata acttagcaat gataaaaaca tatcgaacat agcagtatct aggagttcat
     1681 ttccagtatt aaaatctaaa aactgtgcat ctagtatttt taatgctact tttttctgtt
     1741 tcataaaggt aactgtattt tttatgtctt cataatctct gcctaggcga tccagtgatg
     1801 caacaatgac acaatcacct tctcggatat aatttagtaa tttttgaaac tcaggtcgct
     1861 ggatatcttt accactggct ttttcttgga ataatttatc aatgttaagg tcttccatca
     1921 ttgccaattg tcgatctaaa ttttgatctt gtgaagacac tctaatatat ccaatttttg
     1981 ccataaaaac tccttttaaa aaatgatata atttacatgt aaaatttact tgtagtttta
     2041 ctgttatcat agcattttta aaaataaatt ttaagtctac ttataattta ctttggaggt
     2101 tttgaatgaa tgaaattaag cgcaataaaa attcttttgg tgtttattta ggagagccta
     2161 gctcggaaca gttaaataaa ggtgaagctc gtcatgctct atgtcgaaat atattttatg
     2221 gtagaaaagg caaactttat caaacttatt acgacggtat ggaggaacag ctcaacgcat
     2281 taggattagt aactaatgct atcatatatt ggaattcact atatttagaa aaagtctttg
     2341 aacaaattaa aacggaaggg ttcgactgtt ccgaagaagt gttacgcaag caatttccat
     2401 taattagtga tcacattaat tttgttggca aatatagttt ccgctatgaa aaagaattat
     2461 cgaatggaat actacgtccg ttaaatatag agaattattg agaatgttcg tcttttggtt
     2521 cctaccgtgc attttcgcac ggatgttcca gatactattt ttgaatgtat aaaattgaaa
     2581 acacaagaat actaataaat caacgattct tgtgttttta atttttcact accgtgcatt
     2641 ttcgtttcta tgttccatgt accccaatct tgaaaaatta attaaagact tagataaagc
     2701 cattgacgac ttagtcgtgg tgctaccgga gtatcaatgt ttaaccagta tcccaggtat
     2761 tggtcctgtt taggctgctg gaatactcgc tgaaattggt ccaattgaac gtttttctga
     2821 tgaaataaaa ttgacaaagt atgccggcct atattggcga cagagtcaat ccggtaaatc
     2881 tgaatacgaa aattttttta cgaaaagctt cacgtctaat atctatttta aaataaaaat
     2941 attcctgcta atttggaatc gtttccttct tttggtataa taatacctga aattcttttg
     3001 agaggagttg ttcgtgaagt gaaaactact atgaaggatg ttgctgcgtt agcaggagtt
     3061 ggtgtgggta cggtatctag agtaataaat ggagtaaagg tgaaagaggt taccaaagaa
     3121 aaagtaatgg ctgcaattag tgagcttaat tatgagcctg atgaatatgc cagaggtatg
     3181 aaaacgaata gtagcaatac aatagctctt attttaccta cgatttggca tcccttcttt
     3241 tccgagtttg cctactatgt agaggaagct ctcagccaaa aaaattataa gctttttttg
     3301 tgtaatgcga acggcagtgc ggaaaaagaa aaagaatata tccaaatggt caagcagagt
     3361 aaagtagacg gaattatagg tattacctat tcagacattg ataaatatgt atcatcaaat
     3421 ttaccatttg tcagtataga ccgccatttt tcggaacagg tttcttatgt aacggcagat
     3481 aattatttag gtgggcaaat tgccgctcaa gaactactta ctcgtaactg taaaaacttg
     3541 tgctatgttg ggggtgtttc accttaccct aacgaaacaa acaatcgtaa agctggtttt
     3601 tacaatattt gtgaggaaaa taaaatagct gtgaaggtat tggatatgcc tgaaccaatt
     3661 agcaatttag aggaacaatt gctcgctttt ttttcggata atcctgaaat tgatagcatt
     3721 tttaccatca atgatttcat ggctttggat gtgataaaag cccaaaaaaa actagggaag
     3781 gaagcaccta aggattttca aattattggt tttgatggag tcaagctatc gttgcaaaaa
     3841 gactatttac tatcaacgat tgtacagccg atagaggaaa tggccaaggt ttcagtagaa
     3901 acactcatgg cgatgatttt aaatgaagaa ccgcctaagc gtgtggtagt accggttttc
     3961 tttcacgctg gagagacgac taaagagtaa aaaaccggtt tataacgatt tttttgagat
     4021 aggttgacag aaagtgattt caatgatatc ttaaaaccaa ttaattggaa acgttaccaa
     4081 ttaattgaaa aataaaacgg aaacgtttca aaaaatagga ggaacatcga tgaaaaagag
     4141 aatgttagca attgcagcaa ttttagcatt aacagctgga ggacttgcag gatgtggcag
     4201 taaggagaaa agttcaggta gcagtgatcc aggagaaatt aagatttggg ttcagttttc
     4261 tgatgaaacg cctgaaggaa aagcttgggc agagattgtg aacaatttta atgatgaata
     4321 cgagggtgaa tataaagctg ttactgagta tattcctcgt agcggaagcg gcggtggata
     4381 tgaggataaa gtaaatgctg caattacaac caataccctt cctgatgtta ttacgttaga
     4441 tggaccgaat actgcagctt atgctcattc aggagtcatt gctccattag atgattattt
     4501 gaaagatgcg gacatggatg atgtattaga cagcattatt cagcaaggaa cctacgatgg
     4561 caaaatgtat gcgtttggtt tctcagagtc cagtgtgggt gtctattaca ataagtcgct
     4621 gttcaaagat gctggaatta cagaagatca attgccgacg ttagaagatc cttggacttg
     4681 gacggaattt caagcaattt gccaaaagct gactgataaa tacaaaacgc ctgcaattga
     4741 tatgcaaatg gcgtcgggag acgaaatgct gacctacgca tatacaccat ttatatggtc
     4801 gaatggcggc gatgtcgtta atgctgatgg aaccaaagcc gaagactatt ttaacggtaa
     4861 aaaatccgtt gaagcgttgg aatttattca agaattggtt gaaaaaggtt acaccacaat
     4921 cagtcctatt gaaaaaggat ttgaaactgg caaatatgcc atgatgctga gcggttcttg
     4981 gacaatggca gatttagagg aaaactatca agagattgat tatggtattt tgccttaccc
     5041 cgtttcagat gcaactgggg agttagtttc accaaccgga agctggcagt tagcaatgac
     5101 tgagaaaaca gagaaaaagg atgcttctgc ggcctttatt aagtttgcaa ccagtacaga
     5161 atctagtcgt attatgagtt tagggaacag tgttctacct atcagaaatt caacagttga
     5221 tttaattaaa gatgaagtgt cggaaggaat gcaggtatta attaagcaaa accaactttc
     5281 tggacatgcc cgcccagtgg ttgtagctta tccgcaagta tctagagcat tccaacaagc
     5341 agttcaagat attagctact tcgaggaaaa cccagatgta caaaaagtag cagatagtcg
     5401 cgctgctgaa atgcaacagg caattgatac ttcactaaaa tagaagtttc taaagggggc
     5461 caatcaagtg ttaaaaaaac cgacaatgaa agacaatttg ataggttacg gctttctagc
     5521 gccagctttg ctgctgctga cgatttttct gatcataccc gtaatcatgg taatttatta
     5581 tgcctttact gattattatt tgttaacgcc agatgctaga caatttatcg gcttagaaaa
     5641 ttttaagcga ctgttcgctg atccaatttt tgtaaaaagt atttggaaca cggctaaatt
     5701 tgttgtttgg attattccgg tccaaatagg ggcagcttta ggaatggcac ttattatcaa
     5761 caaaaatcgt aaaggaaata tcttttttaa agtagccttt tttgcgccag tcgtgatgtc
     5821 cttagtcgtt atttcgattt tatggttgta cttgttaaat cctaatgaag gtctggttaa
     5881 tacgctattt gcaaagattg gaattgcttc gcagcctttt ttgactagtc ccaaacaagc
     5941 aatgtatacg cttgttttcg tatcggcatg gcaaggtgca ggatatcaga tgctgctgtt
     6001 tttaggggga atgcaaaata ttccgcaaga cgtttatgag gcagccgaaa ttgatggttt
     6061 ttctaagttt cagcaatttc gctatatcac catgccatta ttaaagccca cggcgatttt
     6121 tattttactt accacattga tttcggcctt taaactaatc attcagccaa tggtaatgac
     6181 tcaaggtgga ccaatgaatt ctactatgac aatggtttat tacatttacc aaactggatt
     6241 tacagaccgt atggtaggct actccagctc cattgcgtta atctttacca ctatgattgg
     6301 tttaattaca attgctcaaa gaaaattggt aaaggaggat gatccagcat gaccaagaaa
     6361 tttggaccgc taatgatcgt agaatattgt ttgctgttcc ttttagcggc attattcatt
     6421 ttcccgatgc tgtggatggt agtttcctct atgaagcctg aagcagatgt ctatcaaaat
     6481 ttagcttcct tcaaagcttt tttacctagt ttgaatccag ctaattggtt taaaacttat
     6541 caagaggtta tttcccggtt cagtgtggga acttatttat taaacagtat tttttatggt
     6601 ttaacctttg cctgtgggtc aatcattgta aactctttgg cgggttttgc ctttgcgaag
     6661 gttaattttt caggcaagaa aattatcttt ggagctttgt tagctctgct gattgtcccg
     6721 atggagacgg ttttaattcc gcaatttacc atcgttaatt cactaggctt agtgaatact
     6781 cgcttggcag tgattttacc agcgatggcc agcgcgttta atatctatct gtttagaaat
     6841 ttctttatcg cgattccaga agaaatcatt gaatcagcga aattagatgg tgcaaatatt
     6901 gttaaaattt tctttcacat catgctgcca atgtctaaac cagccatagc cacagtaggt
     6961 gtcttatcct ttatctccag ctggaatgat tatatttggc cgttaatggt cttaactgac
     7021 agcagcaaat tttcaatgca agtggcaatt actacgatca atactacaca gccagtttat
     7081 atcaatcaag tgatggctgt tttaaccatt gcaacgattc cactgattat tgtttatatc
     7141 gttgcacaaa aatatattct gcagggactt ggcggttctg gaacgggtat aaaataggag
     7201 tgaatagtga atgttgcaaa aacttttaaa ggccaatgag tttattgaga aaaatgctca
     7261 aacagtcaat caagaatacc ggaataaatt tcatttgatg gctccgattg gctggatgaa
     7321 tgatccaaat ggttttgttt attatcaaga ggagtatcac ttgttttatc aatattatcc
     7381 ttacgacagc atctggggac caatgcattg gggccatgct aaaagcaagg atctaattca
     7441 ctgggagcat ttgccagtag cactggcacc aggtgaaagc tatgacaagg aaggctgttt
     7501 ttccggcagt gccatagaaa aggatggcaa gctgtatttg atttatacag gacacaatgt
     7561 tgtggaaggg caagttcgac aagttcagtg tttggcagtt tcagaagatg gcattcactt
     7621 tgaaaaatat gccggaaatc caatcatcgc agaagatcac ttagcttctg ttgcaacgac
     7681 cgaagatttc cgcgatccca aagtgtttca gcgaaaagaa gactatttta ctgtagtcgc
     7741 tactaaaact gcagatgctc gtggacaaat tgtgatgttc cattccaaag atttactaac
     7801 ttgggagttt tattccgtat tgctggaggg aactccagaa caaggcattg tatgggaatg
     7861 cccagacttg tttgaactag atggcaaaga agtcttgatt ctttctccta ttcaaatgac
     7921 tccacaaggc aatgcttacc aaaatacgaa ctcaactgtt gctttcatcg gtactgtcga
     7981 ttggcaaaca ggcaaatttc tagtagagaa ttttcatgaa atcgatggcg gtttagattt
     8041 ttatgcaccc cagacctgtg aaaacgaagc aggccaaaga ataatgattg cttggatgca
     8101 aatgtggcag cgtaaaatac ctacgaatga tctgggccat ggttggtcag gttccatgac
     8161 cttgcctaga gagctgaggg tggctgataa tcaattgttg caacggccag tttcatcaat
     8221 ttatcaagta attgatccgc aggaaaggat tgaatgggcg aagactgaag agaatcgctt
     8281 cttactgaag gacttagtat atgaccagca ctatttacgc ttggaaatca atttaaaaca
     8341 ggcaacgaaa ctagaacttc actatgcgaa gggacccgac catacattac tgcttaacta
     8401 tgatgttgaa cgggagtgct ttactgcttc cagggaacac atgccgtatg atttatcagg
     8461 agctgaaaag gaagtgttga aaaagcgcag tgtgacgatt cctttggaaa ataattgtct
     8521 aaccatcgaa attttccgtg atacttcagc tattgagctt tttctaaatg atcgtctgac
     8581 tatgagtaca actttttatg agacagaaaa aggacaggat tttcttttgc tggcagacag
     8641 tgaagtaacc ttttcattgg aaagcggctt aattaatcta tagaagggag agctcagtga
     8701 tgatttatgg ttcaatcgaa gcaggcggca caaaatttgt gtgtgccatt agcgatgaag
     8761 aaatgacgat caaggaaaga gtgagctttc cgacaacgac acctgaggaa acaatacctt
     8821 tagtcattga cttcttcaaa caataccaag cagatttagc agggattggg attggctcat
     8881 ttgggcctat cgatatccat cgcgattccg ccacttatgg gtacattacc tcgaccccga
     8941 aagtggcatg gcaaaatttt gatttcatcg gtaccatgaa aaaagaattt ccgatcccga
     9001 tttcttggac aacagatgtc aatgcggctg cctatggtga gtatgtcttc ggcagtggca
     9061 aaggattgag cagtgtcgtt tactatacga tcggtacggg tgttggcggc ggtgccttac
     9121 aagaagggcg ctttatcgaa gggtttagtc atccagaaat ggggcatatg ctcgtcgtcc
     9181 ctcatccaaa agatgacttt gctggcagct gtccatttca tggcaactgt ttagaaggga
     9241 tggccgctgg acccgccatc gaaaaacgct tagggaaaaa aggacaagag gttgcagaag
     9301 atgatcctta ttgggaaatc gaagcctcct atattgctca atgtgcctac aatacaacct
     9361 tgatgttttc tccagatgtg atcatttttg gcggtggtgt gatgaaacaa cgccatatgc
     9421 tgcaaaacgt ccacgacgca tttgcaaaat tggtcaatgg gtatgtcgaa acacctgagt
     9481 taagcaaata tatcgtgacc ccagcattag aagacaacgc tggaacgctc ggttgtttgg
     9541 cattggctcg agaagcggtc ttacattcat aaacgaaaaa aggctcttcg acatttagtg
     9601 ttggtagaga aagatacaac tgaaaattta gtcataacca gttaggcaga gtgcttaact
     9661 ggtttttgtt ttacttggaa gatcaagcct tgaatgagat aagttcttgc tcgaaagtta
     9721 tggaaatttc gatagccgta ggctacttgt attgtgcaat agttttttac aaaaaaaagg
     9781 gggtgcggat attttttttg gaccttttta acaaatatat ctttgcttct tccgatattg
     9841 aagagggctt agccttccta aagataactt aattcgttga ttattatacc aatgaatata
     9901 atcatccaat ttgtttataa actgattgat tgttgtattc ttccagtcac gttgataaaa
     9961 catctcgttt tttaatcgtc caaagaaacc ttcgcacgct gaattatctg gtgaataact
    10021 ctttttagac atagagtgaa gcaagttggc tttgttccaa tagtccaact aacaatagca
    10081 ccatcgtaac aatcgacaag tggtgataag tagattttcc ctgcgagaat tctaaattca
    10141 gtaatatctg ttaaccattt ttcatttggc ttctttgctt taaaattccg atttaataaa
    10201 ttggggtgtg caggagaaat ttccccagca tacgaagaat acttttttcg tctagaaaat
    10261 ttaacaaata gattttcctc agtcatcaat ctacgtacaa ctttttcaga aagcttttta
    10321 cccatatttt ttaaagcttg gtgaattcta cggtaaccat acgcacagaa gttatgattg
    10381 aaaatcgtga taattaattt gacgttcttt gtaatactta tctggtttct caagtgcttg
    10441 tttttgataa aaatagctgc ttttaggaaa ctggagctgt tgaagaagct ctttcaaggt
    10501 gaactgattt cgtaaggcat caatcaatat cgttttttct tgatttgata gacaaagaag
    10561 attgacgcct ttttcttttt ttagcagttc agccgctcct tcgagtaatg ctttttcgag
    10621 ctgtaattgg tgtacttgtt tttgtaagtc ttctacttcc tttaaaagta gctctttttg
    10681 tttttcctga ttttttaaag tcatacacaa tggaaaatcc tttccaagaa ccgtgttttt
    10741 ccattgatat agagtaactc tactaattcc tccagattcg gctaaatttt tcctattagt
    10801 ttgcggttta tagaattttt tcaacacagc ttctttttga tcttgtgtta actttaccgc
    10861 actttttcgg agttttctag ctcctggtgc aagttcttca caccgctgcc gcaaggactc
    10921 tctattagga taaccaagca tgcgaatggt tcgtgcataa cattgaccat attcaaaata
    10981 atgattcacc gctattcgtt tttgttcttc agaatacttt gatttttttc ggtgctcctg
    11041 atggagctct ccggattcca aatactcttt ataccatttc cgtagtgcac caatcgacgg
    11101 ataccctaat tctcgaatgg ttgcagcata agagcaatcg tattttaaaa ataactgaat
    11161 tgcccttaca cgctctttgt gggaaaacac acggacattc ctcctaagtt tattttttcg
    11221 tccaggatta tgtccgcacc cccttgcttt ctgatgactt attctggttc tttgagtgtc
    11281 aatgcataga tgtgatgtag ctagttagaa aaaaattttg aatactcttt ttttctttca
    11341 gactcctttt taagtaagat tttgaagtgt gagttacggg gtcagaaact taaaagtttt
    11401 tgatccttta ttttcaagtc tgatttggca gcttttcggc agctcattta tttatggtca
    11461 gaaatagatg ctgaaatttt aatctattag caaatagtcc agaacgtatg aagaggagtc
    11521 ggatatcatt tgtcattaac accataaata tttataaaat tcgtgttcac ctaca
//
LOCUS       DACDAF010000083        11464 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.086, whole genome shotgun sequence.
ACCESSION   DACDAF010000083 DACDAF010000000
VERSION     DACDAF010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11464
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.086"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(47..1342)
                     /gene="purB"
                     /locus_tag="IVZ69_002165"
     CDS             complement(47..1342)
                     /gene="purB"
                     /locus_tag="IVZ69_002165"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HAP8184229.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(1355..2488)
                     /gene="purK"
                     /locus_tag="IVZ69_002166"
     CDS             complement(1355..2488)
                     /gene="purK"
                     /locus_tag="IVZ69_002166"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HAP8184230.1"
                     /translation="MINLVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVS
                     DCPAAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTD
                     LLAITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKG
                     QYVLKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHN
                     NILHETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRP
                     HNSGHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENK
                     PDWQFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            complement(2472..2960)
                     /gene="purE"
                     /locus_tag="IVZ69_002167"
     CDS             complement(2472..2960)
                     /gene="purE"
                     /locus_tag="IVZ69_002167"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HAP8184231.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            complement(3376..4683)
                     /locus_tag="IVZ69_002168"
     CDS             complement(3376..4683)
                     /locus_tag="IVZ69_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HAP8184232.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            complement(4686..5267)
                     /locus_tag="IVZ69_002169"
     CDS             complement(4686..5267)
                     /locus_tag="IVZ69_002169"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HAP8184233.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     regulatory      complement(5383..5480)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            complement(5839..7131)
                     /locus_tag="IVZ69_002170"
     CDS             complement(5839..7131)
                     /locus_tag="IVZ69_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP8184234.1"
                     /translation="MKKKYVQVGLGGRARFFYETIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     gene            complement(7128..7751)
                     /locus_tag="IVZ69_002171"
     CDS             complement(7128..7751)
                     /locus_tag="IVZ69_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184235.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            complement(7754..8590)
                     /locus_tag="IVZ69_002172"
     CDS             complement(7754..8590)
                     /locus_tag="IVZ69_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HAP8184236.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            complement(8607..9494)
                     /locus_tag="IVZ69_002173"
     CDS             complement(8607..9494)
                     /locus_tag="IVZ69_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HAP8184237.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            complement(9510..10793)
                     /locus_tag="IVZ69_002174"
     CDS             complement(9510..10793)
                     /locus_tag="IVZ69_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP8184238.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
BASE COUNT         3457 a         2572 c         1918 g         3517 t
ORIGIN      
        1 tatttttgct attctatttt aattgaattt tgcaactcac tcttctttat tccaaaccta
       61 ctcgtttgaa tatcacgtca acgtttttca aatgatgatg ataatcaaag gcatcgtcta
      121 tttcttcttt agataatacc gatgtgatgg ttggatcttc ttctaacagc gggcggaact
      181 gcacttggtt gtcccaagcg tacgcagttt ttggctgaac aagatcataa gcttcttctc
      241 ttgtcattcc cttatcgatc aatttcagca taacgcgctg gctataaatc aaaccaaatg
      301 ttgcagacat attccgcttc atgttttcag gaaagaccgt tagattttta acgatattgc
      361 caaaacgatt taacatgtaa ttcaataaaa tcgtggtatc aggcaagatg attcgttctg
      421 ctgaagaatg agaaatatct ctttcatgcc ataatgtgac attttcatag gcagtgacca
      481 tgtgtccgcg caccactctg gctagaccag ccatattttc tgaaccgatc ggattccttt
      541 tgtgcggcat agcagaagaa cctttttgac ctttcgcaaa aaattcttct acttcacgtg
      601 tttcggattt ttgcaatccg cgtatctctg ttgcaaaacg ttcaatactt gtagcaataa
      661 gcgccatcgc tgagaaatat tcagcatgta gatcccgagg gagaacttga gtagagattt
      721 cttgtggacg gatccccaat tgtttacata catactcttc aataaatggc gggatatttg
      781 cgaacgttcc cactgctcct gagatttttc ctgcttctac tccttttgcc gcatgttcaa
      841 atcgttcgat gttccgtttc atttctgaat accatgtggc aagtttcaat ccaaaagtag
      901 ttggttcagc atggacaccg tgtgtccgac ccatcatcac tgtatatttg tgttcttttg
      961 ctttttcgcc aatgatttcc gtaaaacgtt tcaagtcttc ccgtaaaata tcatttgctt
     1021 gcttgatgag atagccataa gcagtatcta cgacatccgt acttgttaga ccataatgga
     1081 cccattttct ttcttctccc aatgtttcag aaaccgctcg tgtaaacgca acgacatcat
     1141 ggcgtgttaa tttttcgatt tccaagatcc gatcgatatc aaatgatgca tgctcacgaa
     1201 tttttttcac atcttcttgc gggatttcac caagttctgc ccaagcttca tctgctaaaa
     1261 tctcgacttc gagccacgca cggtatttgt tctcttccgt ccagatattc cccatttcag
     1321 ggcgtgtata acgttctaac atgttttttc tcctctaatc ccaaatattc gtttgtttga
     1381 tttcttccag cgtttgctgg atgtcttctg tcaagatagt gatatgtccc atcttgcgac
     1441 ctttttttgc ttgttttttt ccatagaaat ggaattgcca gtctggctta ttctcaatca
     1501 agcgatagct ttccagcagt tgttctccca aaacattgac cattactgca ttgcttatca
     1561 aacgtacttt ttctcctaat ggccaaccac aaatacctcg aatatgggca tcgaactgac
     1621 tcatagaaca agcttcaata gaataatgtc cagaattgtg aggacgagga gctaattcat
     1681 tcacatatag cccgcctgtt tttgttaaaa acatttctac ccctaaaaca cctgaaaggc
     1741 tcactgcttc tgcaatcaca cgggcaatac gctcagcctc ctcgatcaca tcctgatcaa
     1801 tcgcggctgg agcaatcgtt tcatgaagaa tattgttgtg gtggatgttt tccacgaccg
     1861 gaaaagtcgt gaaatctcct tgaccatttc ctgccaccat gatcgaaatc tctttttcaa
     1921 acgggatcca tgcttctaaa acacaggttc cttctcttaa aaggtccatg gcaggagcta
     1981 gatccgcccg acttttcaaa acatactgcc ccttgccatc atagccgcct cgagtggttt
     2041 tcaaaacaca aggatagccg atcccgtcaa tcgcatcttg gatatccgtc ggactgacga
     2101 tcgttgcata aggagcaatc acgatgttat tcgtttccaa aaaagatttt tctaacaggc
     2161 ggtcttgcgt aatcgcaagc aagtctgtcc cttgaggaat aaatgacatg ggtaaaatcg
     2221 catttaacgc ctctacactg acgttttcga attcataggt aatgacatct gttcttctgg
     2281 caagctcttt cagcgcaaag gtgtcatcat agacactttc aatgtgccaa tctgcaactt
     2341 gtgcggctgg acaatcgctc acaggatcca gcacacctac tttaaagccc atttcttttg
     2401 cactaatcgc catcatacga cctaattgac cgccaccgac gatcccgatc gttgaaccag
     2461 gcaacaaagg tttaaccaag ttgatcacta ctttctataa cagttttagc caacattgaa
     2521 cgtctttcag ccaatttagc ctccaattct aaatcataca tggaaagcat ctgtatcgca
     2581 agtagtccag cattaattgc tcccgctttt ccgattgctg tagtagctac aggtactcct
     2641 ccaggcattt ggacaatcga aagaagcgaa tccaaaccat ttaatgttcg tgattggacc
     2701 ggtacaccga taaccggcaa agttgttttt gatgcgacca tacccggcag atgcgcggct
     2761 ccccctgctc ctgcaataat gattttgatt cctttttttc gagcgttttg tgcatattca
     2821 aacatcaaat ctggggttcg atgagcagaa acgacctttt tttcataaga cacaccgaat
     2881 tcatccaata tttgacatgc ttctttcatt gtttcccaat ctgaagtact ccccataatc
     2941 acagagattt ttgctgtcat tgtttttcct cccagttttt ctacattcat attttaacaa
     3001 tcactttttt tgatgtcaaa gaaatttcga atgttaacaa agaaaaacat tttattgttc
     3061 gtgtttatta aagataaaaa aaaggaatgt gacaaaagtt aggtcacatt cctttttatg
     3121 gataaacggt gttctcctgc caactcctcg gtcacaagga acaatattca acaaacatga
     3181 gaagcttttt tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc
     3241 ttccttcaac ggtgttcaat cagctgaccc tcggtattag ctcaaacaaa cggcaaaata
     3301 cgaggaacta tttttccgtt tgtttctcta acaatcaggt caaaacgctg atttcacaac
     3361 ctttcttttg ctctattact tcttgaaggc ttcttccaat atttcttcat cttttttcaa
     3421 tccattaaag atcaaattca atatgatagc cgtaatgcta ctcattacga tgccatttcc
     3481 agtgaacatt tgcaatgttt gcggcatttg actgaataat gtcggcgtaa cattgaaacc
     3541 cagcccaaat ccaacagaaa cagcaacaat caatagattt ttatcattgc tgaaatcaac
     3601 ttccaacagc atacggattc cttggactgc caccatcccg aacatgacta acattcctcc
     3661 accaagtacc ggctcaggga tgatttgtgc taacgcaccg attttaggga ataatcctaa
     3721 aacaatcaag aagaatgcag agaaatagat gggttttctt gttttgattc ccgaaagttg
     3781 aaccaatccg acattttgag aaaagccagt ataagggaat gtattgaaaa taccgcctaa
     3841 gataacggca agtccttctg cacgatatcc ctttttcaat tcttcttctc caacattttt
     3901 cccagtaatg tcaccaagtg caaaatatac acctgttgat tctaccatgc tgaccatgga
     3961 aatgatgatc attagtaaaa tcgaccatac gtcgaaagtt ggtttaccaa aataaaaggg
     4021 ttgtggaaca tggaacaacg gcgcatctcc aatcgcgctc agatcaatca ttcccatgaa
     4081 agcagctaag atgcttcctc cgactaaacc aatcaatacc gcgattgaac gaatgaaccc
     4141 ttttgccagc atttgcacgc ctacaattag gagaatcgtc acaaatgcaa gtagcagatt
     4201 tgttttgtca ccaaaatcag ctgctgttgc attacctcca cccattttct cgattgctac
     4261 aggaatcaaa gtcaaaccaa taacggtgat aaccgttcct gttactatag gagggaatag
     4321 ttttttaatt ttagaaaaga caccagaaac taacacaaca aagatcccag aagcgataat
     4381 agatccgtag atagctccta ctccttcatt ggttccgatc aagatcagtg gagctactgc
     4441 ttggatcgca catcctaaaa cgacaggcaa gccaattccg aaaaatcggt taactgtcaa
     4501 ttgcaataat gtcgctaatc cacacataaa gatatcaatt gaaatcaaat aagtcatctg
     4561 ttcttgatta aagcctagtc ctgtaccgat caaaagaggc accgctactg ctcctgcata
     4621 catcgctagc agatgctgca gccctaaaac cgcagctttt ccattttgtg tttctttttc
     4681 cacgattatg cgtcctcctc aagaaactca acttgtccat tcgtcaagga agcaatacgc
     4741 gcaagagaaa cgactctcaa tcccatttct tcaagtaact gacgtccatc ttggaaagac
     4801 ttttcgatga cgatcccgat tccttctact tgcgctccag cttgctggca taattcgatc
     4861 aatccttttg ccgcttgtcc gtttgccaag aaatcgtcga taatcaatac tttgtcttct
     4921 gaagataaaa atttacgaga aatagaaatc gtacttgtca cttgtttcgt aaaagaataa
     4981 acagaagctg tcaataattc ttcatccatc gtcaaacttt ttgcttttct agcgaagatc
     5041 attggaacat ctaattctct tgcagcaaat aaagctggtg cgatcccaga agcttcaatg
     5101 gtcacaactt tcgtgattcc ttgttcttta aatacttctg caaaccgttt tcccatttgt
     5161 tccatcaata cagggtctac ttggtgagtg acgaagctgt cgacttttaa tacgccctcg
     5221 cctaatatac gtccgtcttt ttgaatacgt tcaactaatt ctttcacttt atttgctcct
     5281 ttatcattta ttaataccga aataaccgct tttgtgcaaa aacctactat gtttctgtta
     5341 aagaaaaaca ccctccactt tatcataaga aaagaagggt gaaatagcca atcttttact
     5401 tatagtccag catttacggt actggctaga aactgtcatc catattatga cgatatataa
     5461 gtaggtatgt aaaactaata atagtgtaaa ttcattttct tgcaactgtt ttgcacgtga
     5521 aggcagtttg ccatatttga ataaaaaatg ttgtttcaaa tattgaaaac agtctaacac
     5581 tactttctga aactgacaac gtggtttact tatttttttg taaaatctaa tgatttttaa
     5641 tgcattattc ctttttgttc gggtttaaat agttattttt attttctcct atctaaaaaa
     5701 gcagcccaca taaaaagaag gcatgacaaa aagcatgtca tagccccttt ttccgaataa
     5761 atagtgttca aaagacagcc tatcggcaat aaggcaagat tttataaact acgggaagta
     5821 atttccgtaa atctattctt attcttttaa gctgacaagc tcgtcaatca ctactgcttt
     5881 tcctgaagca atagaatgat ttgctgcgat tcctgtcaaa atcgacaaaa taccatctac
     5941 gtgagttgct gcccgattcc acggatcttc ttctttttct tcaccaaata gatcatctaa
     6001 taaacgcgga tctcctccgc catgtccgcc cgcttcttgt tcgacgatta cctcatatgg
     6061 ctcaccgaac atcggataga catggatgga ctgaagaacg gctgctcctt catccttttt
     6121 atctccacct gcattgatgt aagacttttc gatcactttc atttcgatcc gtcctttgct
     6181 gccattgaaa gaaacattga atccttccca cggcatatac gcgtttagcg aatacgtcaa
     6241 aatcgcacca gtttcatatt tgaccgttac gcctagtgta tcttcaatag agatatcatc
     6301 ggaaaataca ctgcggtcac gaatatatcc actgtctttt tctgcttcta aatacatttc
     6361 tcgcaattcc tcattggctg acaggtctat agcaaatgga tcagctttag ctagttcgct
     6421 tccatagcat cgactgtaaa atatttctac tccgcgtttc tccgcattat gcatcccata
     6481 aaagtttaat ccaccgaatg caaatacctt ttggggacgg ctgttcaacc aaaaattcac
     6541 tagatcaaaa tgatgggtag atttatgaac aagaagcccg ccgctattgt gcttatttcg
     6601 atgccatctt ctgaaataat ctgccccgtg ttgcgtattt aacagccatt cgaagtggat
     6661 agaaaacaca tcaccaatca catcactttc tatcagttcc tttatcttcg tgtgatacgg
     6721 tgcataacga taattaaaag tgactcgcag gcttcttccc gtctgttttt ggaccgttat
     6781 tatttcttga gctttttcct catcgatagt cagaggtttt tcgcaaataa catcatatcc
     6841 ttttttcatt gcacgaatga tataatcatg atgcgttcga tctactgacg taataatgac
     6901 ttcagccggc cgtacgtcat ccagtagttg ctcaaattgt gatggcatac atgtctttac
     6961 ttttttctgt ccatacttgt tcacaagtat ccgatttgca taatccatcc ttgtttgaga
     7021 tacatcacaa aaaccgacta gttcacaagt ttgatgatac gtagaggcaa ttgtctcata
     7081 aaaaaaacgc gctctcccac caagtccgac ttgtacatat tttttcttca tttaaagtca
     7141 ttctcctttt cttttaagca aaatactgtg acaaatggca gccctggata cagtaatgca
     7201 gtgagtaaaa aatcatgctg tatacaccag aacagtccat acaaaaggca taaataccac
     7261 agaaacccct tgacgttttt tgacaacagc cagatattcc ttttgatcaa ataaacaaga
     7321 ctatctgctt tatcttcttt gcagatatca attagcgtac taaaaaaact atgggataca
     7381 aaaagcaaca gacacaatag aaaaggaatc agataccaag ctccaatctt tcccactaat
     7441 aaataccaat caactgcaaa aataatgaca aacagctgaa acaacgtaat gatgaaacac
     7501 atccgtttga tttttccttt cctccaacat accttttttt ctgccaagta atggacagat
     7561 agataataag aaggatacat catcaaaaaa taaatcagat agacaacacg agcagacagc
     7621 actaatccta aagtgaacaa acatcctaga actaaagcga aaagagcatt actgataaga
     7681 ctggttaaaa aaatccgaca gacatagtag ttgagcttgt aaagaaacat ctcttctatt
     7741 ggctttttca tattcagccc ttcagaccgc ttgtactgat cccctggaca agatatttat
     7801 tgaagaataa gaaaatcaga aaaaccggta gcagcgacaa cgtagacatc gcaaacatac
     7861 tcgcgtaagt cgtactagat ccagcgtctg caaataattt gatggcaatc gataccgtgt
     7921 aagatctcgg cttgtttaaa taaatcaatg gtcccatgaa gtcgtcccat ttccaataaa
     7981 actggatgat gatcgtcgtg atgatcgaag gtttcagcaa aggaaaaata attttggtaa
     8041 agacactata cttgctgcat ccgtcaataa tcgctgattc atctaactct ttggggatgc
     8101 tgaccatgaa ttgcatgatc tggtaaatga aaaatgcttg tccaaaaaaa tgtggtaaaa
     8161 tcagcggcac atacgtccca accaaattca gccgattgta aataataaac tgcggaatca
     8221 aaatcacttg tgcaggaatc atcatcgtta ctaacatgac gacgaaccag aatctttttc
     8281 ctttgaaatc gattctcgat aatgcgtaag caatacaagt cgagctcaga actgtcccta
     8341 tcgtcgaaac tgcagagatg acaaacgaat tcctaaagaa agtaaaaaat gaaattccag
     8401 caaaccccgc ccatcctttt gcgtaatttt cccattgaaa agtctctgga atcaaattca
     8461 gcgaaccact cataatctct tgatccgttt taaaagaacc tgcgatcatc cataagaccg
     8521 gataaatcat gactagacct aatagcaaaa taaaaccgta ttgaaaccat ttcgttactg
     8581 tattattcat ttcttcctcc tctcattcac acaacgaccc atttttttga tgatttgaaa
     8641 atcagaaagg tgacagctcc cataatcaac agcatgatcc acgaaatagc actagcatac
     8701 cccatagaat taaaagaaaa agcttggtta tacacataaa gagcataaaa gttcgtggca
     8761 tcattcggac caccttgggt aatgataaat gcctgcgtaa aagtcataaa cgccgcgatt
     8821 gtctgcataa ccaagttata caaaatgatc ggcgaaagaa gaggtaacgt gatcttgtaa
     8881 aacgtctgcc atttgttcgc tccatcgatc tctgccgctt cataatacga gcctgggatc
     8941 tctttgatac ctgcagcaaa gatgatcatt gccgaaccga attgccaagc agacatcaaa
     9001 acaagaggga tcatgaccag tttttgatcg ctaaaccagg aaagcgcagg tgcgcctaat
     9061 cgttccagga aaatattcac taacccgttt ttagaaaaca actcccgcca aactagagcg
     9121 atagaaatac tgccaccgat caaactaggc acataataca aagaacgaaa gaaagtcgtt
     9181 cctttgatat tcctcgttaa aagataagca atcaatagac caaagatcag tttcacaggt
     9241 acagatgcaa atacatagag aaaagtgact cggatggagt tcaaaaaacg ggcatcactc
     9301 agcatcttta tataattatc caagccgatc catgagactg gatttcccaa acgataatcg
     9361 gtgaacgaat aataaagtga caagatcatc ggtatcactg ttatcaatag aaatcctagg
     9421 atgaatggag aagcaaatac gtaaccgacc acattgtctt gatccaagaa ccgttttagt
     9481 ttttcttttt tcatgccttc ctcctgctgc tatcctagaa tgtttgacgc aaactcataa
     9541 agactctctg ctgcttcttc tgctgttact tcttcataaa tgactttttc aactaaaaga
     9601 ttgtattggt cttgaatttc cggattcaaa gcactatcaa agacattcac ttcgccgttg
     9661 tccatatcgg aaatcatttc taaataatca aatgtcgctt gcaaagttgc atcatctgca
     9721 cgagcgagct gttctcgaat attcgacatg attggtacac cacgttctcc ttttaaaatt
     9781 tcattggctt cttcactgtt ttgaaagaaa tcaataaact tagcagcttc ttctttatgg
     9841 gctgagcttt ttgccatact cagcatttgc gaagaacgta aagggatacc agattctcca
     9901 tctgcttttc tgcgaggtgg attaatcaac tgaatctcca tatcttcagg agcccctgac
     9961 aatatttctg tcaactggtt acttgataga aacaccattg ccgcttctct atccctaacc
    10021 gcctgaaaag acagatccgt cgtacttgca gctccaccac ctggttctgg atgggcccct
    10081 ttgtctacca gatttttacg cagctggaaa aaatctgtta gatagtctgg attttcaaat
    10141 cccaagctgt tagatagatc ttcccgatta taaaaattca atcctttctc aacttgtggt
    10201 atttgaataa tacagccagc tataaaatct tcgaatcttg aaatagcata gattcctaat
    10261 tcttcagtga tttgatagct gatttgttca aattcatccc atgtccaatt tgaagctggt
    10321 tcagggatat ttaattgttc aaatatattt ttattgtaag caatcgcaaa cgaattcacc
    10381 ccgttagaca gtccaactaa ttgcccgtcg taagtcgtcg ttgctaaata ggattcatct
    10441 gcattagaaa tatcaattat cccttgctcc acatattcat ctaatggttc aatctgattg
    10501 atgtattgag gaaattgatt gttcagttgg aaaatgtccc agatatcatc tgatgctgct
    10561 agtgtaccta attttgtgta atatccttca taatcataaa attcataatc gatcgtcaca
    10621 tggggatttt tttcttcata aagctcgatt acttttactg ttgcatcgtg tcggacttgc
    10681 gaaccccacc aagccatgtt cagcgtgatt tttttgtcat cttcttgccc acaagccgtc
    10741 aagaagaata acataacact taaagctaag atgattctca ttcttttctt cattctctgc
    10801 acctctactt ccattgttat ttttcaatat actgtatttt tatacagaac atatttatta
    10861 aacgatcttt ttcaagggga ataaaaacca agacttgcct tatcgttctg cctaggatga
    10921 acaactcaat actttcaaga aaaattagat agtgctgatt cttctttcat cgctaaaaac
    10981 acttcttgct tcaatgatgg gaggataatt acgcaaagaa aaaaggatat cagacaactg
    11041 cccaatatcc ttgacatagc taaataagca tgcttcttcg tgtgcgctct tccctaaaaa
    11101 acagaaaaat aactagtaat tctgtatgaa attaggtaca atatacacgt cgatgcacaa
    11161 gcattgacta tggcaacttg attggtcagt tcccgctgac ttttcaagcc ccgacaattt
    11221 agctgctact aaattgtcgg gtgccttttt tagtttttat tcgtttttca ttctatagaa
    11281 agcgcttcaa taaatcaaga catttttttg ttagaatgct aataataaca aaaggtttta
    11341 actcttctta tgtacattac aggtaaaaaa acaaaaaaat ttctcttttt tttgaattct
    11401 gaacaaatag tactggagta caaaagacga ggaagagcca ctatctgctc ttcctcgtct
    11461 tttg
//
LOCUS       DACDAF010000084        11254 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.087, whole genome shotgun sequence.
ACCESSION   DACDAF010000084 DACDAF010000000
VERSION     DACDAF010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.087"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="IVZ69_002175"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="IVZ69_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HAP8184239.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="IVZ69_002176"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="IVZ69_002176"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HAP8184240.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="IVZ69_002177"
     CDS             complement(2169..2906)
                     /locus_tag="IVZ69_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP8184241.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="IVZ69_002178"
     CDS             complement(2997..3524)
                     /locus_tag="IVZ69_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HAP8184242.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="IVZ69_002179"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="IVZ69_002179"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HAP8184243.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="IVZ69_002180"
     CDS             complement(4401..4886)
                     /locus_tag="IVZ69_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HAP8184244.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="IVZ69_002181"
     CDS             complement(5039..5236)
                     /locus_tag="IVZ69_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184245.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="IVZ69_002182"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="IVZ69_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HAP8184246.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="IVZ69_002183"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="IVZ69_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HAP8184247.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="IVZ69_002184"
     CDS             9211..9423
                     /locus_tag="IVZ69_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HAP8184248.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="IVZ69_002185"
     CDS             9425..11104
                     /locus_tag="IVZ69_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HAP8184249.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3265 a         2429 c         1971 g         3589 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaat
//
LOCUS       DACDAF010000085        11222 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.088, whole genome shotgun sequence.
ACCESSION   DACDAF010000085 DACDAF010000000
VERSION     DACDAF010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11222
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.088"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            64..687
                     /gene="lexA"
                     /locus_tag="IVZ69_002186"
     CDS             64..687
                     /gene="lexA"
                     /locus_tag="IVZ69_002186"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HAP8184250.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            867..1085
                     /locus_tag="IVZ69_002187"
     CDS             867..1085
                     /locus_tag="IVZ69_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184251.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(1374..1886)
                     /locus_tag="IVZ69_002188"
     CDS             complement(1374..1886)
                     /locus_tag="IVZ69_002188"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HAP8184252.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(1900..4197)
                     /gene="recJ"
                     /locus_tag="IVZ69_002189"
     CDS             complement(1900..4197)
                     /gene="recJ"
                     /locus_tag="IVZ69_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HAP8184253.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(4339..4773)
                     /locus_tag="IVZ69_002190"
     CDS             complement(4339..4773)
                     /locus_tag="IVZ69_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HAP8184254.1"
                     /translation="MKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPLILV
                     IIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQREFRN
                     ERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(4783..5571)
                     /locus_tag="IVZ69_002191"
     CDS             complement(4783..5571)
                     /locus_tag="IVZ69_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP8184255.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(5568..6509)
                     /locus_tag="IVZ69_002192"
     CDS             complement(5568..6509)
                     /locus_tag="IVZ69_002192"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HAP8184256.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(6686..7273)
                     /locus_tag="IVZ69_002193"
     CDS             complement(6686..7273)
                     /locus_tag="IVZ69_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HAP8184257.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(7494..8807)
                     /gene="obgE"
                     /locus_tag="IVZ69_002194"
     CDS             complement(7494..8807)
                     /gene="obgE"
                     /locus_tag="IVZ69_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003126661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HAP8184258.1"
                     /translation="MSMFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGG
                     DVILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAET
                     GALLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVL
                     ADVGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLE
                     RPQIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNAT
                     ADLLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTN
                     FDHDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            9104..10114
                     /gene="gap"
                     /locus_tag="IVZ69_002195"
     CDS             9104..10114
                     /gene="gap"
                     /locus_tag="IVZ69_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HAP8184259.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(10199..11134)
                     /locus_tag="IVZ69_002196"
     CDS             complement(10199..11134)
                     /locus_tag="IVZ69_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP8184260.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3127 a         2511 c         1967 g         3617 t
ORIGIN      
        1 tcgtttgatt tagcgctttt tatatggtac tatttattta tcaagtgaaa gaaggtgtac
       61 cttgtggccc gacaaactga atcaagacaa atcgaagtct tacgatatat ccatgaacaa
      121 gtaacccaaa aaggataccc gccgactgtc cgtgaaatcg gggaagctgt tcagctttct
      181 tctacttcta ctgttcacgg tcatcttgca cggcttgaaa aaaaagggtt tatccaaaga
      241 gatccgacga aacctcgtgc aatcgagttg acaaaacaag gtttagaaaa gattgggatt
      301 cgtccaacaa ctattccagt acttggcgtc gtaacagctg gagaacccat tttagcagta
      361 gaggatgctt cagacttctt tccaatccct cctaatcttt cttccgaaga aggcagtctc
      421 tttatgctga caattcgtgg agatagtatg atcaatgctg ggatattgga tggtgacaac
      481 gtgatcgttc ggaagcaaga aactgctcaa aatggcgata ttgtcattgc aatgactgcc
      541 gaggacgaag cgacttgcaa acgattctat aaagaaaaaa actttttccg tctgcagcct
      601 gaaaacgact tgctcgaacc aatcatctta gatcaagtat ctatattagg acgagtagta
      661 ggactttatc gtagtcatat ctattaattg ctactaatta aaagaaaact ttttaaaaag
      721 agtttgagac gttggtctca aactcttttt tcgcccgggt tcttcttctt tcaaattttt
      781 atcacttccc tctttacaaa ccgaacaaat attcgtatac taaatatacg aacaattgtt
      841 cgcataaatt aaagaggtga gaattcatga aatcaatgag acgtcttggc ttagtattaa
      901 ctgttttgtt tttaggtatt attattggta atttcggcat acgtccagct ttacttgtgt
      961 ttgttccgtt atttactttg tggttcatgt tgtgggatga aaagaagtac cgtcaatctg
     1021 agcggcgcag aattcatgaa gatcatttct atcatgagcc ctactacaga tccaggcaat
     1081 cataataagg attgactgct aattattcaa aagacaagaa gttaaacttt tacgggggtg
     1141 tgacaaaaat cggtcacatc ctttttttcg aataaacggt gttctaaagc cagtttttcg
     1201 gtattaagtc aaattgcgga aaaagtgatt ttttaaactt ctactggtct ttgcttgttt
     1261 ccatttataa aaaaatagcg accctcaaaa gtcagataga gaatctgact tttgagggtc
     1321 gctttaaaat cgcttcttta agaataacat caagaatagc ttcttttttc tgcttaatat
     1381 tccattaatg taatgatgtc atatcctttg attttgtcgc gtccatggag atccatcaat
     1441 tcgatcaaaa atgcgcagcc tacgactaca ccgcctaatt gttcgatcag ttcgatcgtc
     1501 gctttgattg ttcctccagt agctagcaaa tcgtcacaaa tcagcacacg ttgacctggt
     1561 ttaatggcat ccttatgcaa tgtcaatgta tctgttccat attctaatcc ataagtcact
     1621 tcgatggttt ctcgaggtaa cttccctttt ttgcggactg gggcaaaacc gactcctaac
     1681 tcataagcaa caggacatcc tacgatgaat ccacgggctt ctggcccaac taccatatca
     1741 attcgttttt cttttgcata atttacgatt tgtttagtag cttcccgata agcgtcacca
     1801 tctgccatca gtggggaaat atctcgaaac acaattcctt ttgacggata gtcgggaata
     1861 ctggcaatat aatcttttaa atccactctt tgtttcctcc taggttgtta accatttctt
     1921 tatggtagga atatcgctca aaagcaaaaa ttcctcaact ttgattttat tgagccgtcg
     1981 ctggtataat ctgctctcag tcaaaggatg actttctggg ctagcgactt tttgtaaaac
     2041 accgttctct attgtaacaa atttcaattc aaaaaacacc tgtatcataa aaattaataa
     2101 tttttcaggg atacgcaaat attgagctat tgcttttatt ttatgacgta tatcaattcg
     2161 ttcttgagaa tggatcaatt taaacaattt tgcgtactgt tctcttgtgc ctaccccatt
     2221 caaataggcc tcatcaggtg aaatccccat cagataaaca cgattgaatg aataagaccg
     2281 aaaaacttct ttcagatccg ctaaatcatc tggacaatcc ataacaacta gagagtttgg
     2341 ttttcttttt tcaattattg cctttacaga atctagtcct tcgaaaacaa tcgcagcttc
     2401 ctggataatc tcaggcacga atttcaacgt cgaagaatca aatgctaaat aaaggctacc
     2461 ttccgacgtt cggctctgtt cacggaaacg ttttgcccgc caatcaaata cttgcagacc
     2521 acccacagaa aaatcagata ccatcagctg cggtttctta cgcccgttcc attcattgat
     2581 cgaaagcttt cctaccacat ctacctgatt attcagcagt tcttcttctt gagtaccaaa
     2641 accaaaagcg accgcatcaa gctgactcga tgcatcggaa aggacaaatt tcagatgctg
     2701 ttggtttgct ccgattcttt tgatattttc tgcttggact tgtcgaaata aaaactgagg
     2761 caaaggatta tccgtaccaa atggcgccaa tagtttcagc tcatcaattc gctctactgt
     2821 tacttcattt ggcagcaata cttcatcaat tctcaactca ggccctctca tcaagtcaat
     2881 ttgatgatcg actatatatt ggttcatctt ctcctgtagt atagtgacat tttcacttgg
     2941 catcgttaaa ccgactgctg catgatgtcc tccgaagtaa gtaaataaat ctcgcatctg
     3001 gtcaagcatt tcaaaaagat tcaaggcttc aatactacgt ccagatcctt tagctgatcc
     3061 atcttctttt aaagtaagga caagagttgg tttacccgtt tcattcatta ttttcccagc
     3121 aacaatgccc aaaacgcctt catgccatcc tcggtttacc aatagatgga tatgattctc
     3181 cttattgacc atcgctaatg cttcttgtgt tatctgctct acgattgctt ttctttcttc
     3241 attgatctca ttcaattttt ttgcttgaac ggatgcttcc tcttcatcaa acgtcgcaag
     3301 taacgagacg gcaggacgtg gatcgcccat ccgaccgatt gcatttagtc tgggagcaat
     3361 cgaaaaaccg atcgttgttt cgtctgcgtc cctcattttt acgccgcttt cttcaaatag
     3421 cgcctgaagt cctatccgtt ctgaatgatg aatggcatcg attcctaatg aaacaaggat
     3481 tcgattctca tcagtcaatg aaactaaatc ggcgatcgtt cctatcgcta ctaaatccaa
     3541 aaattctgca ggcggttctt ccaataatgc agaagctact ttgaatgcta ctccgactcc
     3601 tgccaaatct ggaaatggat agtgccccgc tggatgacga gggtgaacaa tcgcataagc
     3661 gtctggtaaa ttctcaggta gttcgtgatg atctgtaatg atcacgtcta caccagcttg
     3721 ctgagcgtat gctaccgcat catttcctgc taccccgtta tcaacagtga tgatcaactg
     3781 gattccttct tcgatctttt cttggtatac cgattggttt ggtccatacc catgctcaaa
     3841 tcgatttggc aggaatactt ctacttctgc accaagtaat tccagtgttt ctttcattac
     3901 cgttgcactg gtgatcccat ctgcgtcata atcaccgtaa acgaggattt tttctccact
     3961 gattacagct tcttggattc ggctgattgc tttatccata tcgtgtatca gatacggatc
     4021 atgtaattct tgttcctttg gatgtaaaaa tcggttgata tccttttcct catggtaacc
     4081 tctttgccac agtaacttac cgacaaatgg agataatttc agttcacgga tcatttggag
     4141 aaaggattca gaaggctctg tctcgcttaa cttccaatca aaatttgctt gtctcacttt
     4201 ctcactccta acttagttat tatagcaaag gaaatcagca aaaaaaagca gaaagaaaga
     4261 ataaaaacag atcagatccg ctagacagat gttcagcagg acctgatctt ttgtacgacc
     4321 atttatgaaa tatccctatt agtcaaaata attgaagctt tgtttgggcg attgagtttt
     4381 ttgttcttcc ggcgctttca attgactgat ttgtgcggtt ttcgcttgta actccgcctg
     4441 ataagcagct tccaactccg cacgttcgtt tctaaactcg cgttgctgtt cttcttttgc
     4501 ttcttcaatt ttcttttgaa gttctgtttg atattctgac atttcctgag tcagctgttt
     4561 gatttgcttt ttttgctgcc atagtgttgc cgaagcagtc aaaaatacaa tcagtgcacc
     4621 aatcagcgca gaaccgatga tcactaagat caatggcgca gaaaaggaag tgaagccaaa
     4681 acttacagga acatttttat tgttcaatac agcaaaaaga acaataatca aaactaaaac
     4741 aaatccaaga atcacattgc tttgcttttt caattccttc acctactttt tgttaaaaat
     4801 tccgctggct aaataatcac caatcgttgg aaacagcgta taaaattttg atgcaacttc
     4861 taaaataaac ggttgattga tttcccgttt tggatgtctc atattgcgga cgatcatttt
     4921 tgccaacttg gcaggttcta aaacgatttg tccgactttt tccaaatagc ttccgcttgg
     4981 atcagcctta tcgaagaaat ttgtctcgat tggacctgga ttcactgtcg taacagctac
     5041 gccaagtggt ttcaattcta atcgcaaagc gttggagaag ccaaggactg caaatttcgt
     5101 ggcagaataa accgttgatt ttgcagttgc catttttcca gccatagagg cgatattaat
     5161 gatatgacct tgtcttcttt ctgccatatc gatcgcaaat ttttgtgtca aaaccatcat
     5221 tcctaagatg ttgacttcaa acatatcgta tgcttttcca aggtcgaatg taaggaagtc
     5281 ttcgaaaatc ccaaaacccg cattgtttac cagaatatcg acgcgcccga cttcttccat
     5341 caccttttca tataattcgt ccacgctttc aggattgctg acgtctacct tgaaagcata
     5401 agcctctttg ccgctcaagc gtctgcactc gtctctgaca ccttctacaa atgccattct
     5461 tcgtgcgcaa cttataacga ttgctccttg ctttgctgct tcataacaga tttgtgcgcc
     5521 cagaccgcct gaactacctg ttactaaaac aactttatct tctaaattca tgcctcttcc
     5581 tcctcgcgaa atggaatctc aatgctatca aaatctttca taatcgtcgt gttttcaaac
     5641 acttcttgtg cttctttttc aagctctaaa gctgcttttc ctaaatatct cgcactgata
     5701 tgagtaagta gcagccgttt tgcctgcgct tcttttgcaa cttcagcagc ttgatgagtc
     5761 gtggaatgga aatagttgtg cgccattctt gcttcatctt tattaaatgt gctttcatgt
     5821 accagaatat cgctattttc cgcaagcaca acggaattat gtgtttttct cgtatcgcct
     5881 aaaatagtca cgattcgtcc ttttttatct ggacctacga aatcttttcc attgatcgtc
     5941 cgcccatctt ctagttggat cgtttcacct tgcttcagtt tgccgtacag tggtccagct
     6001 ggaataccta attcttttag acgatccacc tgcaattctc ctttatgatc atgttcaacc
     6061 acacgataac caaaactgtc gatcccatga tttagttttt ttgtataaac agaaaattgc
     6121 tgatcagtaa aaatcggggc tgtttcattt agctcaatga atttcagcgg ataacttaaa
     6181 cgcgtttgcg aaatacctaa agagactttt atgtattcct ctatcccttt tggcccgtaa
     6241 atctctaatg gcgtatcccc accttgaaat gaccggctgc tgatgagccc gggaagtcca
     6301 aaaatatgat cgccgtgtaa atgtgtaatg aaaattttac cgatttttct cggacgaata
     6361 gtcgttcgca aaatctgcat ttgcgtgcct tcgccacagt cgaacaacca aacttcattg
     6421 cgctcgtcta aaagtttcaa tgctatactt gtcacatttc tatgttttgc aggaacacct
     6481 gcacctgttc ctaaaaattg taattccata atctacctga ctttctttaa gttcctcttt
     6541 aattttaggg taaaaagaag ggataatcaa ccgtaagtcg agaatgggtt caaattaaaa
     6601 ataacgttct aaagcgatag cgttttcttt gaaaattact ataaaaacag cagcgaaccc
     6661 gtttgagatc ctctgctgtt ttttattaat ttgaagatcc agaactttca ttgtcgttgg
     6721 aagtttgcgg atgtttgtcc ttccaagtct tttgtgcagc ttctttcgca tgattttcag
     6781 cttctttcgc atcatgcaca tctttttcga catcttcata atccaagcga gtaatttctc
     6841 cgcctaattc catcattacc aattgattca gtgggcgatt gtcctcttca tcagcaatca
     6901 agatcagtcc tgtagctcct tcaccgattt tatttcctac aaagtcgaac acggtctggg
     6961 catcttttat ttctttggca tcttgtgtcg caccgatcat tcctccggca aaccatccta
     7021 ataaaatccc tagcggacca cctaatacac caaccaacat tccgattaat ccacccgtag
     7081 aagatttgtt attaccggta aagtcgataa aatcttctat tttgaattga tgtgtcccat
     7141 taggatcatg gctgacaact gccatctgtt ctcctttaat cgaacgaaca gcatgtaact
     7201 ttttgatttc tgaaaatgcc tgatatgcct ggctttctac ttgaaaattt aaaatgatta
     7261 ctcgtttgct cattaaaaac gcccctttca taccttcttg ttatttattt tacctttaat
     7321 tgtaaaataa gaaaagaaaa gcactctttt tttccaataa aatagggctg tgacaaaagt
     7381 cgtatcacag ctcctttttc cgaataaacg gcgttcttga agctgatcac ttctgtcaca
     7441 acctccctta aatctgaatc tatatttttt ggtatttgtt tttatttgct tgcctattcg
     7501 acaaattcaa attcaaactc accgatacgt acaaggtcgc catctttcgc accgcgtgcc
     7561 cgaagagctt catccacacc cataccacgt aattgacgag caaaacgcat cactgtttca
     7621 tcatgatcga aattcgtcat ttggaataat ttttcgatct tctcaccaga taagatccac
     7681 gttgcatctg aatcacgatc gatttggaac tcaggacctt ctggattgaa tccatagtgt
     7741 acagtttctt cttccagttc ttcttcgtac aatgggaatt ctggcgttac ttctaacaaa
     7801 tctgctgtag cattcaataa cgcgtccaat ccttgtcgag tcactccaga aattggaaat
     7861 actgggatgt catcagcaaa ttcatcttct ttttccttgt tcagctgttc tttgaatttc
     7921 actagatttt ccggtgcatc cggcatatcc attttgtttg ccacgatgat ttgcggacgc
     7981 tctagcaagc gtaagttata agtagataat tctttgttga tggcaagata gtcttcataa
     8041 ggatctcgtc cttccatccc actcatatcg atcacatgta aaattactcg tgttctttcg
     8101 atatgacgaa ggaattgtgt acccagccca acaccttgcg aagctccttc aatcaagcct
     8161 ggcaagtctg ctgcggcaaa acttctgcca tcacttgtag taaccattcc tagattaggt
     8221 acgagcgtcg tgaaatgata agcgccgatt tttggacgag cagatgaaat aacggatagt
     8281 aaagtcgatt tcccgacaga tggaaaacct acaagtccaa cgtctgccaa tactttcaat
     8341 tctagttcga tttttcgctc ttgtcctggt tcaccgtttt cagcaatttc cggtgcagga
     8401 ttccgaggag aggcaaaacg gatattccct cgtccaccgc gtccaccttt tgccacaact
     8461 agtgtttgac cattttcaat taaatctcct aaaagagcac cagtctccgc atctcggaca
     8521 gtggttcctt gtggtacttt aacataggta tcttctgaac cacgaccgtg catcccttta
     8581 ctcatcccat tttcacctgg ctgcgctttg aaatggcgat tgaaccgaaa atccatcaat
     8641 gtacgtaacc cttcatcgac gatcaagatg acatcgccgc cacgaccacc gtctccgcca
     8701 gccggtccgc cgtcaggaac gtatttttcg cgacgaaatg caaccattcc gtctccgccc
     8761 ttgccagctt tcacatcgat cgttacttga tctaaaaaca tggacataat taagtcctcc
     8821 tattattcat ttatttattt gactgcctga atttccacaa taaacaaaag tcttacttat
     8881 tttatcggtg aaatctgatt ttgtctatca tttcagcaaa aagattgttt accttcttct
     8941 ttttttatca tttggtaagg tttccaacct tttttctgct accaagtata attttttgac
     9001 aaaatattct ttgcgtagca gaataacagt gtattaattg tattaattgt attaattgag
     9061 gatgccgttt cacagcaccc ctaataaagg aggaactttt gatatgacag taaaagtagg
     9121 tattaacgga tttgggcgta ttggccgtct ggctttccgc cgcatcaaag aagtctcaga
     9181 tgatattgaa gtagtagcaa tcaacgactt aacaagtcca actatgttag cacaattatt
     9241 gcaatttgac tctactcatg gtacttatcc tggcacagtt actgcaacag aagactcaat
     9301 cgtagtggat ggcgaagcaa ctcgtgttta tgcagaaccc gacgcaagca aaatcccttg
     9361 ggcaaaagaa aacggtgtag atatcgtact agaatgtact ggtttttata catctgaaga
     9421 aaaagcaaaa gcgcatttag atgctggtgt caaacgagta gttatttctg ccccagctgg
     9481 tgctatgaaa accatcgtct ataacgtcaa tgatgataca ttagatgaaa acgacaaaat
     9541 catctcagca ggttcatgta caacaaactg tttagcacct atggcttatt tcttaaataa
     9601 tgaatttggg atcgaagttg gtacaatgac aacagttcat gcctacactt ccacacaaat
     9661 gctcttagat ggacctgtaa aaggcggtaa tttgcgtgct gctcgttcag ctgctgacaa
     9721 tactatccca cattctactg gtgctgcgaa agcaatcggc ttagttatcc ctgagctaca
     9781 aggaaaatta caaggacacg cacaacgtgt tccagtcgtt gatggttcat taactgaatt
     9841 ggtttcagta ttgaaaacaa aagtaactgc tgatcaagta aacgaagcaa tcaaaaaaca
     9901 cacagttgac aatccttcat tcgggtatga tgaccgtcaa atcgtttcta gcgatgtcat
     9961 tggaacaact caaggttcga tctttgaccc aacgcaaaca gaagtaacaa ctgctggtga
    10021 tttccaactt gttaaaactg ttgcatggta tgacaatgag tatggattta cttgccaaat
    10081 gattcgctta ctagaaaaat tcgctaactt gtaatttgat agatcaatcg ataaaagaag
    10141 cctttgactg gatccagtca aaggcttctt tcttttcatc ccctactttt aaactcgttc
    10201 aatgaacata ttggcttaaa aattgttgga ctacttgctg atatttttca ggatctgtct
    10261 tgtatgcttc cgcatgctcg gctcctttta caacatactt ttcttttggt cccttcgttg
    10321 cacgatagac cttatctaac atttcaaatg gtacaaatgt atcttcgtct ccatgtataa
    10381 agagcattgg gcgctggttt ttcttcaatt gttccactgc atttgcttca ccgaaaaagt
    10441 agccagcacg gacttttgtc actagactcg ttacttgcat aagcggaaat gctggaagac
    10501 taaacatatc gtctagctga taagcaagct catcatgaac ggaagaataa ccgcaatctt
    10561 caatgattgc tttcacatta tctggtagtt tttctccgct agtcatcata actgttgctg
    10621 ctcccatgct gacaccgtat agaacgattt cttgcgattt tccattgttt tctagcactt
    10681 tgtttatcca ctgtacatag tctttacgct ctggccatcc aaatccaatg taatcccctt
    10741 cgctttttcc atgtcctctt gcatcaggaa caaggacatt gtaacccata tcatgaaaca
    10801 tctttgcgta attggtcatc gtttcagcgt ttcccatata gccatgagcc acaagagctg
    10861 ttttttcact tttcgtttca gcaggaagat aaatcgctga taatttcaga ccgtcttttg
    10921 aagtgatggt ccaatcgctt cggttttctt ttgaactaaa ccatttatgt gcatccgttt
    10981 ctttggatgt ctgtgttgta ccaggtgtat cttcgtctaa aaagtctttc tcagaaggca
    11041 caacagcata attataaaaa taattccctg caaacactaa cgcaacaatc agagctaaag
    11101 cgacgcctaa aaggattttc atccaaagtt tcataaatca tccatctcat ttctcttttt
    11161 tcatataacc ttgaattagt ataatcaaag aatctctact atgcaatgtt catttttata
    11221 ac
//
LOCUS       DACDAF010000086        11150 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.089, whole genome shotgun sequence.
ACCESSION   DACDAF010000086 DACDAF010000000
VERSION     DACDAF010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11150
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.089"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            6..305
                     /locus_tag="IVZ69_002197"
     CDS             6..305
                     /locus_tag="IVZ69_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8184261.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="IVZ69_002198"
     CDS             378..1739
                     /locus_tag="IVZ69_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HAP8184262.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFLSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLLFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGILTMPIYLYGATYLAPILSDSAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="IVZ69_002199"
     CDS             1761..2021
                     /locus_tag="IVZ69_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184263.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="IVZ69_002200"
     CDS             2035..2787
                     /locus_tag="IVZ69_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HAP8184264.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="IVZ69_002201"
     CDS             complement(2881..3486)
                     /locus_tag="IVZ69_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HAP8184265.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIEQAREWTDHLLTK"
     gene            complement(3542..4516)
                     /locus_tag="IVZ69_002202"
     CDS             complement(3542..4516)
                     /locus_tag="IVZ69_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HAP8184266.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DCPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4894..5673)
                     /locus_tag="IVZ69_002203"
     CDS             complement(4894..5673)
                     /locus_tag="IVZ69_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8184267.1"
                     /translation="MLLRVVGSIIFRYTLEEVNNVPKYEEIANILRERIRSKEYPPDS
                     FLPNQVDLVKEFGASRMTIKKAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEY
                     EGLSLQMKRRHRSLKSQIIHFDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVL
                     EHTFMPVHLVPGLKKEHLLASIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAE
                     NDPVLEVQQVVYLKDGQPIEYSSSRNRFDVRNYSVLDVRST"
     gene            complement(5740..7011)
                     /gene="celB"
                     /locus_tag="IVZ69_002204"
     CDS             complement(5740..7011)
                     /gene="celB"
                     /locus_tag="IVZ69_002204"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HAP8184268.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7164..8561
                     /locus_tag="IVZ69_002205"
     CDS             7164..8561
                     /locus_tag="IVZ69_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP8184269.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWNHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSRLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKAIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGTIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8642..9082
                     /locus_tag="IVZ69_002206"
     CDS             8642..9082
                     /locus_tag="IVZ69_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP8184270.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9229..9555
                     /locus_tag="IVZ69_002207"
     CDS             9229..9555
                     /locus_tag="IVZ69_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP8184271.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9556..10305
                     /locus_tag="IVZ69_002208"
     CDS             9556..10305
                     /locus_tag="IVZ69_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184272.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10331..10741)
                     /locus_tag="IVZ69_002209"
     CDS             complement(10331..10741)
                     /locus_tag="IVZ69_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP8184273.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNK"
BASE COUNT         3538 a         1948 c         2291 g         3373 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttcgaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcctgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtctta ttgctgcttt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattacca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcctc acgatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgattcagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaaggaccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcaaaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgggagat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc tcgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccaatc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa aaatgaagta gcatgaagag
     3541 attattcacg ttttttattt gcatcacttg tatcgaaagg acggacatag gcttcaatgg
     3601 cttcacgacg ttcttctaag aatggaggaa gagatagttt ttctcctgct gattctgctg
     3661 gttcatcttc aaggaatcca ggacaatcag ttgctaattc aaacagtacg tgatgagcgg
     3721 ctaggaagta ctcagattgg aaatagaaac gatcgacgaa accagaattt ggcaattcaa
     3781 tcttattgat tacttgaatc cagtattcca atgcttcttt gtctgctaca cgcaatgcta
     3841 agtgatggat atttccaaat ccttcgattg cttttggcaa gtctgtccga tgttcaataa
     3901 tgatgcttgc accatttccg ccttcaccga tttcaaataa gtagaaatct cctgaatggt
     3961 ctgtttcttt gaatcctaag attttttcaa gaatcaagcg gatatgctct aattgactga
     4021 cacggacaaa gacaggtcca agtcctgtga tcgcaaactc tgtcggtaca ttgctgtttt
     4081 tccaaggaat gccagctgct acaccttgat tgttttcgtc agagatcaat tgataatact
     4141 gattatcgaa atcttcaaat tcgatatatt ttttgccgaa acgttcattg attgctgaat
     4201 gagtaacgtc atatttttca aaacgttcca accaaaagtc taatgctgcg tcacttggca
     4261 cacggaaaga agcacgagag atcgtatctg ttcctttttt tccttttggc tgatttggaa
     4321 aatcaaagaa agtcatatct gttcctggcg caccagtatc gtctgtaaag taaagatggt
     4381 aagtttcgat gtcatcttgg ttaactgttt ttttgattaa gcgcattcct aaaatatctg
     4441 taaaaaagcg gtagattttt gtagcgctag atgtcattgc tgtgacgtgg tgaattcctc
     4501 tgatttgtgt atccatgata aatttcctcc tgtcaactta caaaaagtaa gtagttgatt
     4561 tagacatagt atagagggtg catctctatt ttgcaattaa tttgtcttct aaagtatcag
     4621 gaaggaatca agaatggaaa agaggaggga cggatcaata aaataaaaag acttacgact
     4681 agctgtatcg atttcaaaaa aactagcttt aaaaagctaa ctttagaatc attacgggtg
     4741 gtcataagtc tttttatgct gagttatttt ttcatttttg agctaatgct taggatagga
     4801 tagaatgttg atttcacgat ctcttcttgt tacttgaaac tgcttactac tgtcacgatc
     4861 tcttggtaaa cggctttttc acaacctctt catttaagtt gaacgcacat ccagcacaga
     4921 atagttccga acatcaaatc ggtttcggct ggaagaatat tcaatcggct gtccatcttt
     4981 gagatagacg acttgctgaa cttccagtac aggatcgttt tctgcacagt tcaaatattg
     5041 ctgatcatat tcatcacttt tatctgcaga aatagcacga taagcccctg caaaatggac
     5101 attcaattct tgatgaagat gatcatagat agaggctaac aaatgttctt tttttaaacc
     5161 cggcacaaga tggactggca taaaagtatg ctctaaaaca tatggctcgc catctaagat
     5221 ccttaaccgg tgaatattgt agacaggttg ctcggcatcg atcatcaatc gttcttggat
     5281 atattgatta gggaattcaa catcaaaatg aatgatttga ctcttcaaag aacgatgtct
     5341 gcgtttcatt tggagactca aaccttcata ctcgttagcg ggcgatgtgt ctttttgcat
     5401 aaatggatga ttcaagattt tcgttcctga tcctcgctgc gaatagacaa gtccttccat
     5461 tgctaagata ttgatggctt ttttgattgt catccggctc gcaccaaatt ctttgaccaa
     5521 gtccacttga ttaggcaaaa aactatcggg aggatactct tttgaacgga tacgttctct
     5581 taaaatattt gcgatttctt cgtattttgg cacgttattc acctcttcta gagtataacg
     5641 aaagattatg cttccgacaa ctcgaagtag catctggaac attgtttatt cgaaaaaaga
     5701 ggtcgtgaca agtttttgtc acaacccctt aatgatctat taagcaatat ctaaatctgg
     5761 ttgtttatct agtactttca ggaatgggta ccagataaag gcaacgatga caaagtcgat
     5821 gacttgcagc ataccaccaa gccatgaatt tgttgctaag acaccgcttg caatgattgg
     5881 cacagtccat ggaacagaga cgccagttgg tgcagggaca agtccagcag ccattaccaa
     5941 ataattgaac gtcgttacga ttagaggtgc cacaacccaa ggaataagga ttgttgcatt
     6001 caatacgatc ggtagaccga agatcgctgg ttcatttaca ttgaaaatac caggtgctaa
     6061 agctaatcgt ccaacatcac gatactgttt ctttttaaga acaaaggcca tcaataaaac
     6121 gacagctaaa gtcattccag agccaccaat accaacagtg aaggtttcca tgaatggttt
     6181 tgtgatgatg tgtggtaatt cttttccatg ttgataagct tctaagttat caagcatcag
     6241 tgtattccaa atcgggtcca ttacagagtt gacgatgatt tgtccgtgaa gtccgaagaa
     6301 ccataagaat tggacaaaga acaaagcaat caatgttgca ggtaaactac ttcccaaacc
     6361 agttaatggt ttttggatca cttcataaac gacgtcatgt aagttagcat tgaaaatacc
     6421 agtcatcaca gcattgatta ctaagaaaat agttagtgtc actacagcag ggatcaaagc
     6481 ggcaaatgat tttgttactg caggcggaac tccatcaggc attttgatct gccagccgcg
     6541 tttcgtgatt ctgcagtaga tttctccagc caagaaagca gcgatcattc caatgaacat
     6601 tccttttgcg ccaagacgat caagtgaaag cacaccagtc acatcttcac cgccagcggt
     6661 tttcattgca aaaggcgtaa gaatcaagaa gctggcaaaa gacacggcac caccgaaaat
     6721 accttcaacg tcataagatt ttgataaata atagccgata ccaaaagtaa caaaaaccga
     6781 catgatgctc attgttgcat tttgcccatt accgaataag ttcgataaag ttccctttgt
     6841 tgcgtcactg aaaaaaggca agttattgat aacgacaacg atcgaaccga acatcgttaa
     6901 agggaaggaa agcatgaaag catcccgcag cactgtaagg taacgatttt gccctaataa
     6961 attagctaag ggcatgattt tctcagaaag cttgtccata aaaccgttca tttttattca
     7021 cctcaaattt atttgcaatc gattacatac aaagtataac gccaaaaatt ttaaatgtct
     7081 agtcattttc ataaaaagta ttgatttatt ttttagggtt cgttatgatt acgatatcaa
     7141 gaaaaaagag aggaagtaaa aaaatgaaaa cctacacatt cccagaaaat ttttggtggg
     7201 gttctgctgc tagcggaccg caaacagaag gaagagtaag tgatgatggt aaaggagaaa
     7261 atatttggaa tcattggtat gaattagagc ctgaaaaatt cttcgatcaa gtaggacctg
     7321 aaaaaacttc gcaagtttac acaaaataca aagaagatgt tcagttaatg aaagaaactg
     7381 gccataacac atttcgtaca tctatccaat ggagtcgttt gattccagaa gggacaggtg
     7441 aaatcaatca aaaagctgtt tctttttatc gagattattt tactgaattg ctggataatg
     7501 gtatcgaacc ttttgtgaac ctttaccatt tcgatatgcc actaccactg caagaaaaag
     7561 gcgggtggtt atcaagagaa acggtcgacg cttatgtttc ttatgcagca gcgtgctttg
     7621 aactgtttgg agatctggtc aaaaaatggt ttactcataa tgaaccaatc gtacctgtag
     7681 aaggaggcta cttgtatcaa ttccactatc caaatcatat caatatgaaa gaagcggtcc
     7741 aagtaggcta tcatgagaat ctagcaagcg caaaggcaat caaagcctac catgaaggcg
     7801 gacatgatgg tgagatcgga atcatcttga atctgacacc aagctatccg agagatgaaa
     7861 cgaacccaga agatgtaaaa gcggcgaaga tcgctgacgc attcttcaac cgatcattcc
     7921 ttgaccctgc agtgaaagga gagtttccac aagagttgat cgaaattgtc aaagaattgg
     7981 ctataatgcc agagatccat gaaggagacc tagaactcat ccgtgaaaac acgattgacc
     8041 tgctaggaat caattactat cagcctcgtc gaatcaaagc aaaagaaact ccaatcaatc
     8101 acgaacatag ccccatgcca gatgattatt ttgataatta cgacatgccc aataaaaaaa
     8161 tgaatccata tcgtggatgg gaaatttacg aaaaaggaat ctatgatatt ttaacgaata
     8221 caagagaaaa ctatggtaat atcaaatgct atatttctga aaatgggatg ggggtcgaag
     8281 gagaagaacg atttgttaac agcgaaggaa ctattgaaga tgattaccgg attgagtttg
     8341 ttacggatca tttgaaatac gtccatcaag caatccaaga aggaaccaat tgtgtgggtt
     8401 accacatgtg gacatgtatg gacaactggt cttggacaaa tgcttataag aatcgctatg
     8461 gctttatcgc tgttgatttg gcacaagacg gtaaacggac gatcaaaaaa tcaggtcgct
     8521 ggtttaaaac ggtctctgaa aaaaacggat ttgatgcctg atattttttg ataaaacgtt
     8581 cacaaaatgt ttgttctaac actgtaatcg tgctacacta acagtgaagg aggcgtttac
     8641 aatggtagat acttatcgta atattttagt agcaattgat ggttctgaaa aggcagaaaa
     8701 agcatttctt gaggcaatca cgattgccaa acgaaatcag gcaacgttgc acatcctgta
     8761 tgtcaatgaa gtaacaggca attactttgg tgattttgca tttgttacaa caagccttca
     8821 ggaagaattg gatgaggttg cggaaaacca gatgaaagaa catcgaaact tggcaattga
     8881 aaaaggcttg acagatatcg agacatatgt tctttacggt tatccaaaga cactgattgc
     8941 taatttccat gaatcgaaag aaccaatcga tctgattgtc atgggggcga caggtctgaa
     9001 tgcggtagaa cgtgcactag taggttccac tacttcctat gtagtcaacc acgcatcatg
     9061 taacgtcatg gttgtaaaat aaataaatta agggaacaga aagcaaaaaa gcataacgct
     9121 tcttttgctt tctgttcctt taattttttg taaaaaatta ctttacctga tgaagtaatc
     9181 atgctattct aattacaacg acagatggag taatatggag gaaagaaaat gatttcaagt
     9241 gatggaatac gcggatacaa tgatgcgatt attttatcga tccttaacaa aaacgattct
     9301 tatggatatg aaatttctaa aacgattcgt gagaggacaa atgattccta tgtgatcaaa
     9361 gagacaacac tttactccgt ttttgcccgt ttagaaaaga atcaactgat tgtttcgtat
     9421 cctggagaag tgactcatgg aaaaaagcgg acatattata aaatcactga aatagggcgt
     9481 aatcttttag aagaaaaaaa gcaagagtgg ctgacgacga aagacgtagt cgatcaattt
     9541 ttggagggaa attaaatgga tacaatccgt aattatttag acagtctttt tatcggagta
     9601 cctcaaagta ccgagataga taagctgaaa actgatttgt tggcaaatat ggaagaccat
     9661 tatcatgaat tgatgggaga aggaaaaaat gaacaggagg ccatcggtac agtaatttcg
     9721 acatttggtt caatcgatga attattagaa gaactagatg tcgaaaaaaa acatcaagct
     9781 gacgagacgg aaacaaacac agcttctatt tatttaagcg aagcagaaaa ctactggaaa
     9841 gaatacagag cggcaagtct ccaagtggca tcaggtgttc tattcattag cttatctttt
     9901 gcaagttttc ttttcttttg ttcagcaggg tatgtgttca tgggtatttc ttgtctgatt
     9961 ttcggtatag cattagctgt cggttttttt attgcttctg gtatgaaaat cacacgttta
    10021 aatcactttt tgcaccatcg gaaaatacct gaaaaagtat tagcagaagc aaaagaaaaa
    10081 gaagaagagt atcagcgaag ttttggcttc tcactgattg caggaattgg attatgtatt
    10141 ttttcacttt tcccactttt ggcttcttta atgtggtata tggatggtag tatcggtgcc
    10201 tctatatttt ttgttacggt aggaacggga gtcttcttga tcatttatgg cagtctggtc
    10261 cgtcattctt atcgtcaatt cactcaaagt gcttattact ggtgaatgta ttcagatttg
    10321 taaaaatatt ttatttattg cttacccatg taaaatcgtt atagacagat ttcagttgac
    10381 ttctgcgcca ttgtacaggg ataaaaagac gcatactatc ttcattgaat ccgactaata
    10441 atttctttcc gtcagtaatg atgggacgtt gtaacaaagt aaaatgcgag acgatcagat
    10501 cgacaagctc tgaggtcgta cattggtcga tttgatcttt caaattttta taatcaatcg
    10561 agcgtttagc taatagatcg tcaaatccgt tttctgttaa tgacaataaa taaaatatct
    10621 ctttccttgt taaaggctgt ttaggtgtga aaattcgttc tctgtaaggc atttgatggt
    10681 ctttcagcca gtttgccatc agatggtaac tatgtgtgcg agaagaatag atcgtaagca
    10741 taaaaaaact ccttaaatag tccattaatt tgttagatct gttgagataa ataataggta
    10801 aggagctgtg cataagcatt gatcaaaaca acccaaacat cattagaaat aactttctaa
    10861 agtcttaaac ttgcgacgag aaacaactag actaatagaa aaaatgtctt agccatttgg
    10921 cttcctgttt gtttttttgc ttatgctgca gctcctcggg aaagggttct aacaatttga
    10981 agaaggttga tgattgatct agtttaaatt gtgtgaaatt tgaaatctgg tgtttttact
    11041 agatgaatca cctaacaact atgattataa cttatagaac ttctgttttg tacttggttt
    11101 tgttatagtt gttataaagt tttattttat tacagaacat ttttaattaa
//
LOCUS       DACDAF010000087        11035 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.090, whole genome shotgun sequence.
ACCESSION   DACDAF010000087 DACDAF010000000
VERSION     DACDAF010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.090"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(19..294)
                     /locus_tag="IVZ69_002210"
     CDS             complement(19..294)
                     /locus_tag="IVZ69_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184274.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            588..1403
                     /gene="thiD"
                     /locus_tag="IVZ69_002211"
     CDS             588..1403
                     /gene="thiD"
                     /locus_tag="IVZ69_002211"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HAP8184275.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKDAQQETVNDYVLLESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1608..3059)
                     /gene="cls"
                     /locus_tag="IVZ69_002212"
     CDS             complement(1608..3059)
                     /gene="cls"
                     /locus_tag="IVZ69_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HAP8184276.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQKALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3400..6066
                     /locus_tag="IVZ69_002213"
     CDS             3400..6066
                     /locus_tag="IVZ69_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HAP8184277.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNE
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6430..7182
                     /locus_tag="IVZ69_002214"
     CDS             6430..7182
                     /locus_tag="IVZ69_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP8184278.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7204..8358)
                     /locus_tag="IVZ69_002215"
     CDS             complement(7204..8358)
                     /locus_tag="IVZ69_002215"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HAP8184279.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8543..10984
                     /locus_tag="IVZ69_002216"
     CDS             8543..10984
                     /locus_tag="IVZ69_002216"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HAP8184280.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKPYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     KVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
BASE COUNT         3586 a         1950 c         2343 g         3156 t
ORIGIN      
        1 ataaagaaca gttagaagtt aaaattgctg attcacatag agtttatgac ttcttggaaa
       61 ttctttttca atcagttttt tcatctgttt atgaaattct tttttttcag taaacataaa
      121 ggtttgggta tcgtaacctt cttcatgtag gaaatagatt attccttttt ctgtgttttg
      181 cgtataagct tttatactcc tgtctttttt gaaagaacag atcgtatagc catctatttg
      241 gtctggtagt cgtttgattt tcttcaaaat gactttttta tcctcaagtt tcattttttt
      301 cacctgactt tatttttttc atatggaaat catagcgcct ttggttatat gaaaacaaga
      361 aggatactga aatatatata aatcaaatag tggttattta ttattagaat agcgaataca
      421 aacaaatgac aactattttc tgatttatta caaatgtttt ttcaaataaa tttgattacc
      481 aagaaaaggt agtggtatat ttactgaggg atactttgaa aaacatatga tagaaacagt
      541 aacagcatta tgaaaaatct ttttataaaa atggaggaat cgatttgatg gaagatcagt
      601 atgtacaagc aatgacgatc gcaggatcag atagcgatgg aagcgcaggg atgcaagcag
      661 atatgcatac attctttaca agaaatgttt acggtgtttc tgtcatgacc gcatgtgttg
      721 caggtaattc ttacggaatc ggagcaagtg tgacattgcc aacagatttt atcgacaaag
      781 aatttgaact gattgcgaag gactttcaaa tacgtgcagc taaaacaggt atgctagcag
      841 attcaaagtt gattgagaca gttgtaaaaa attaccaaaa atatgatttt ggaccattag
      901 tcgtggatcc cgtaatcgta acgaaacatg gaaatctttt actagaagaa tctgctttgc
      961 aaagcttgaa agaaaagctt gtccctttgg ccgaagtact gacacctaat ttttatgaag
     1021 cagaaaagct gactggacgg acattagcag ctgaagaaga ttttgtgcaa gcagcaaaag
     1081 aactgcaaga tatgggtgca aaaaacgtta tgatcaaagg acatcatgct aaagatgcgc
     1141 agcaagaaac agtcaatgac tacgtattgc tcgaatcagg aaaatcattt tggttaaatg
     1201 caccatttta tcctaccgac cggatcaacg gaactggcga ttcgctatct gcatgtattg
     1261 cagctgagtt agcgaaagga aaaacagttg aacaagcgat ccgattggca aaagactatg
     1321 taaaccgtgc aattcgtgaa gaaataaatg tagggcacaa atatggaccc atcaatcatt
     1381 gggcagctgg tgaattagag taaaagaaag aggtcgtgag cctgccgtcc agctccgagt
     1441 cacaaggaac aagttcaaaa aacagcttct catgtttgtt gaatattgtg acttgtgacc
     1501 gaggagttgg caggagaaca ccgtttgttc ggaagaaggg actgtgacaa gatttttgtc
     1561 acagtccctt taatcttagt atatttttct ctacttgaat aaaaaaatta taggattgga
     1621 gaaaataatc gagaaatttg ttgcttgaat aatagccagt tagacatttc cttgactgtt
     1681 tcagttgtca tggatgaaca atgtgtctca tcttctttga actgagtagc aagttcttct
     1741 aaaaactcag gatcgtaaat gacagcactt gtttcaaaat tcaatcggta gctacgaata
     1801 tcttgatttg ctgaacctac catgcagatt tcatcatcca ttatcaatgt ttttgcatgg
     1861 aggaagccgt tctcatagac aaggatttgt acattttcct tgatcagctg ccgagcataa
     1921 tattgtgttg ctcgataaat aaaaggatga tccggtttgt tgggaatcat gattttcaca
     1981 tctacaccag aggcagttgc gatttttaaa gcagcaatga cactttcatc aggaacaagg
     2041 taaggtgtct gtatccaaac acgtttttta gcagaagtaa tcaatttgat aaatgaaagc
     2101 ttgatttgtt ccctttcgtt attcggtccg cttgaaacaa gctggatgga tgtatcagca
     2161 agcttagatt catctcgatc tgctttttta aagaaataat tcaaatgata gccgaccttt
     2221 ttttcttcag gtaccgagac gttccagtct gttaagaagc gaagctggag caaagaagaa
     2281 gcggcaccga aaatccgtat atgcgtatcg cgccaatagc cgaatttttt tgttgtattt
     2341 acatattgat tggcaatatt gaaaccaccg gtataactaa tctttccatc gatcacaacg
     2401 atttttcggt gatcatggta attcaatcgg aaacgaagta atgccttttg tgaggtaaca
     2461 aatgtatgga catgtccacc atttttgatt agacgattga aatcttttgc ttttgtacca
     2521 tgagagccaa atgcatcata taatattcga acttccacgc cttctgcggc tttttcttct
     2581 aaaacatgta agacttgctg gccgatatta tctgtcacaa atgcgtaata ttcgatatgg
     2641 atcgaatgtt tggctttttt tagatcttga agcagtgaat ccaatttctc ttgtccgtct
     2701 gtgagaagag tgacagaatt cattcttgtc agcggcatac gatttaatga agagaagaag
     2761 tcgacaaatt gctgtttgtc tttatcgccc atgtcaggat cgtaatgttc aatggtatct
     2821 cctctaaaag actgaaagtt ttctaattct ttcaagtcac tttgtcggag atagaatttt
     2881 ttcttatccg ttaatccacg tccgaaaaat aaatataata caaagcccac cccaggaagg
     2941 gcaaacaata ctaagagcca tgcccaaatg gctgctacat ctcggggttt gatcaaaata
     3001 gccaccaaag caataagtgc atttaataga taaagggcgg ttataatact agataccaca
     3061 aaaatgttcc tccttacata caataacatt agtatagcat gatagaagaa agaagcctac
     3121 caaggtgaat atacttttca ctcctttcat gaaaatgtag gtaaatcggg ctaaagtagt
     3181 tgctttttgt aggttaataa ggtaggatat tagtacagtt gaatatctcc ttaggggagt
     3241 aaccggcaac gtttgttgcg ataatatcaa cagtaagtta accaaatggt tttctggtat
     3301 tgtatgaaat ggtgagacct aagacaaatg cgtatttgtc ttaggtctct tttttttcag
     3361 acaggactag ggccaagatc aaaaaatggg ggatgaaatt tggaaaacaa ggaacaagca
     3421 caacaagcgg tctataaaga aacgatcgac tcgttgatgc agcaaacgca gagctcaacc
     3481 gatggattga gcaccacgca agcgaaggaa aaattagaaa gagatggctt gaaccagcta
     3541 aaagaaaagc cgaagaagcc aacttggaaa ttgttcttag aaactttcaa agatgcaatg
     3601 gttatcgtat tgctgattgt cgcactgatt cagatggtca tgggtgacta catcgaattc
     3661 ttagttattt ttgcagtatt gatgttgaat tctataatca gtgttgtcca aacaaaaaaa
     3721 gcagaaggtt ctttagaagc gttgaaaaac ctttcagcgc ccgatgctcg agtgattcgt
     3781 gatggtaagg aaaaaacgat tccggcaaac gaacttgtgg taggagatat cgtgttgtta
     3841 gacgcaggcg attatgtacc tgctgatgga cgtttactag atgcgggatc attaaaagta
     3901 gatgaaggta tgctgacagg agagtcgact tctgcagaaa aagaagtaac ggatatcaca
     3961 agtacggtac caatcggaga tcgtacaaat atggtattca gtggaacgat cgtaacttac
     4021 ggacgcggta aattcttagt gacttcaact gggaataata cggagatcgg acaagttgct
     4081 ggccttttgg aatcaacaac tgagcaagtc actccgttac aacgaggtct ggataaattc
     4141 agtaaaaaac taagtctggc tattttggca ttgtctttat tgattttagg tatccaactg
     4201 tttcgtattt atcttggaga aggtacagga gatatgactg cagatatcgt cagcgcagtg
     4261 atgtttgccg tagccgtagc cgtagctgct attccagaag cattacagtc tatcgtaaca
     4321 atcgtgttat ctttgggaac gaataaaatg gcaaaacgtc atgccattat tcggaagctt
     4381 ccagcagttg aaacacttgg ttcgacaagt atcatctgta cagataagac tggtacattg
     4441 acacaaaaca aaatgacagt tgttgactac tttttaggta atggcgatac tggggatttc
     4501 acaaatgacc cttcaaaatg gacagctgac gaacgtcgct tgatcgaaat cagtgtttta
     4561 gcgaatgatg catcgatcag tgaagacggt actaaattgg gcgaccctac ggaagtagcg
     4621 tttatcgact ttagtgaaaa attaaaccag ccttatcagg aaatccgaaa caactaccca
     4681 agacaagcag aacttccttt cgattctgat cgaaaattaa tgtctactgg acacacgatc
     4741 gataacgaaa attacttgtt tgtcaaaggc ggaccagata tcgtcttcca acgcagtaaa
     4801 aaagtattgc taaatggtga agtcgttccg atgacggatg aattgatgaa aaaattccaa
     4861 gagcaaaatg aagctttttc aacacgcgca ttacgtgtac tagcttttgc ttaccgtcca
     4921 cttgataatt ttgatttatc atttgaagat gaagacgatt tgatccttgt tggtttgctt
     4981 gctatgatcg atcctccacg tgctgaagtg actcaggcgg taacagaagc aagaagtgca
     5041 ggaatcaaaa caatcatgat tactggtgac cacaaaacaa cagctgttgc tatcgcaaaa
     5101 caaatcggga tttttgaaga aggaaacctg gctttgaccg ggacggaact agatgaattg
     5161 acagaagatc aactaaacga agttttagaa aaagtcactg tttatgcacg tgtttcacct
     5221 gagaataaaa ttcgtatcgt tcgtgcttgg caaaataaag gtcatatctc agctatgaca
     5281 ggtgatggtg taaatgacgc accagcattg aaacaagcag acatcggaat tgctatggga
     5341 acgggtacag atgtggcaaa agatgcagca gcgatggtat tgacggatga taactttgct
     5401 tctattgtca gcgcagtaga agtaggacgt aatgtgtttg ataatatcaa gaaagctatt
     5461 tcttatctat ttgcaggaaa tttaggtgcg atcattgcga tcatctttgc cttagttgct
     5521 gactggtcca atccatttac agcattacaa ctgttgttca tcaatttagt caatgattca
     5581 ctgccagcaa ttgcattagg tacagaaaaa gctgaacctg ctacgatgaa ccgcccgcca
     5641 agagatccaa attcaggaat ctttacggac aaaacattga tttctgtaac gtatcgtggt
     5701 gtgctgattg ggattgctgt tatctttgct caatggcttg gcatgcagca ttcacctgaa
     5761 ttcggtgtag ccatgtcatt ttcaacattg atttggtgtc ggacattgca aacattccca
     5821 gcacgttcaa acacacaaac agctatccaa gcagggttct tctctaacag aagtgtctta
     5881 ctagctgtag ttgtatgtag cgcgctttac tgcttaacaa tgatcccagg actgaaagaa
     5941 gtcttctcta tcccatcagc atttggattg acagaagtct ttacatgtat gggaatcgca
     6001 cttgtgacaa ttgttttgat ggaaatcact aaattgatca ttgtacgagt acaaggaaat
     6061 aaataaaacg aatcaacgag gttgtgagcc tgccgtttaa ttctgagtca caaggtgcaa
     6121 tttcaacaaa cagcttctca tgtttgttga atattgtgac ttgtgaccga agagttggca
     6181 ggagaacacc gtttaaggaa gaagttgtaa aatcagcatt ttgagctaat actgagggtc
     6241 atctgattgg acactgttta ttcggaaaga gggactttga cacgactttg gtcacagtcc
     6301 ctttttttat ttatgataga cggaaagcca atcattttat tattcatcaa aagagataga
     6361 atagataaaa gaggagaata atttattccg aaaagtgaaa acatataaca aaaaattaga
     6421 ggaaatcaaa tgaatgaaaa agaatgggat gaatttgctg aagaatatta tgaaatccag
     6481 caagaatcgc aagtaactat tgctgaagat gtaaaaaatt atctgaaaac ggagaaagtc
     6541 ctgcctgctg aaacagcagc agacgttgct ggaggatctg gcagatttct ttccttagca
     6601 aaagaaatta atcgctatga tttgatcgat ttttcttcag gaatgctaga aaatgcaaaa
     6661 aaagaagcag aaaaaaatga gttgccaaat gtttccttta tcaaacagtc gttagaagaa
     6721 tttatccaat caaatgagac atatgaaatg gtttttacag cagcaaatcc agcattggta
     6781 catcttattc aattagaaaa attgatgaaa aagtcaagca aatggtgcgt gataatcagg
     6841 gtagtggaat caatcgatga tgttttttat cctatcgaaa agcaactagg aatgatagaa
     6901 gaagatccta atacatcgcc agttgtaatg gatcaatttg aaacatactt aattgatgaa
     6961 ggattcaaag tgaagaaaaa agattttact tattttacac aggaatcaat tactgaagaa
     7021 ttgatgaagc tatactatga cgcgtacgca aaagatcctg ttgtgaccag gtacattcgc
     7081 aaactattca gtgaaaaacg agaaatcctt agtacgacta agctgaccta tagactgctc
     7141 ctttggtccg cagataaaaa aagaaccttt cacgactcgt gaagggttct ttttatgatt
     7201 ttattatatt ttgtagtaac gaatatcatt ttcgatcttt gtaatcgaaa aaggtacatc
     7261 tgaagtatat tctgcacatt ctccgtgttc aggaagcgtc tcactgaaaa tcgtttcata
     7321 ttcgtcaaca gtgatccgtg ttcgagaatc tagcatctct tgatgagatt gtgcgaagag
     7381 atattcttga tagttttctt ccagataacc tgtaaaaaat tcacttactg caccagaacc
     7441 gtagctgaat agaccgatgc gatctcctgg ctgtagtgat ttcgaatttt ccagtagaga
     7501 agttagcccc aggtataatg aaccagtgta aagattaccg attcgtcggc tgtaacggat
     7561 gctttcttca tagcgagcca taagacgttc ctgattttct tcgtctgttt ggtctaatac
     7621 gctttgcaat gccttttttc ccatcttagt atacggaata tggaaagcaa tcgcctgata
     7681 atcttcgagt cctcgacccg acaattcttt atgtcgattc caaacttttt ggaatgattc
     7741 gatatacgta gaattagata aaggaccatc aacaacagga aattcgctat aatctggacg
     7801 ccagaaatca tagatatctt ctgtcagaaa tacgctgtcg tcttcaatcg ataaaatacg
     7861 cgggttttga gtgatcatca tcgcaacagc accgacacct tgcgtcactt caccaccgct
     7921 tgccaagccg taacgagcaa tatcacttgc tatgactagt acttttcgtt ctggatgatt
     7981 tttgacatat tctttcgcca tgtgcaaagc tgcggtgcca ccgtagcaag cctcttttac
     8041 ttcaaaagaa cgagcaaaag attggatttt cagtaaatgg tggataatta ccgcactcgc
     8101 ttttgaatga tcaatcccgg attctgttcc gacgatgacc atgtcgatta gctcacggtc
     8161 tttttctgtt acgattttgc tggcagcatt tgctcctagt gtaatgatgt cttcatttgc
     8221 acgattgact gccatttggt cttgaccaat ccctatatgg tattttgcag gatcatcccc
     8281 acggctttct gccaactctg tcatatctaa atataaatta ggaataaaaa aggaaagacg
     8341 atcaatccct attttcattt caacacctct ttacttatga taaaaaactt actttactaa
     8401 ggtatcataa aaagattaaa agaaatataa aaaagagaat atttaaggat tgttaaaatt
     8461 taatcttaga aaaaaacaac tggaacaaga gctatttgtt tttacagcaa agaatggtat
     8521 atttttgtag gaggtggctt acttgaaaga agtcgttatg atagatgctg caagaacgcc
     8581 gataggaaag tatcgcggaa gtttaagtcc atttactgca gttgaattag gcacacttgt
     8641 gactaaagga ttattagata aaacaaaact gaaaaaagat aaaatcgatc aagtaatatt
     8701 cggaaatgtc ctgcaagctg gtaatggtca aaatgttgcc agacagattg ctttgaacag
     8761 cggtctccct gtagatgtcc cagcaatgac gatcaatgaa gtttgcggat ctggtatgaa
     8821 agcagtgatc ttagcacgcc agctgatcca attaggtgaa gcagaacttg tgatagccgg
     8881 cggaacagag agtatgtctc aagcacctat gctgaaaccg tatcagtcag aaacaaatga
     8941 atatggtgaa ccaatttcca gtatggtcaa cgacggattg actgacgcat tttcaaatgc
     9001 acatatggga ttaaccgcag agaaggttgc aacacaattt tctgtgagca gagaagaaca
     9061 ggatcgctat gccttgtcgt cccagttgaa agcagcacat gctgtcgaag ccggtgtatt
     9121 ttctgaggag atcatcccag tcaagatttc tgatgaagac gtgttatctg aggatgaagc
     9181 agttcgtgga aatagtacat tggaaaaact gggcacgtta cgtacagtat tctcagaaga
     9241 aggaactgta acagcaggaa atgcttcgcc attgaatgac ggtgcctctg tggtgatcct
     9301 tgcatccaaa gaatacgcag aaaataataa tctgccttat ttagcaacca tcaaagaagt
     9361 agcggaggtc ggtattgacc caagtatcat gggaatcgct ccaatcaaag ccattcaaaa
     9421 attgacagat agatcaggaa tgaatttatc aacaatcgat ctttttgaga tcaatgaagc
     9481 atttgcagct tcttctatcg tagttagcca agaactgcag ttagatgaag aaaaggtcaa
     9541 tatatatgga ggagcaatcg cattaggcca tccaattggt gcaagcggtg cacgtatctt
     9601 gactacatta gcttacggat tgcttcgtga acagaagaga tacggtattg cttcattatg
     9661 tattggtgga ggtttaggct tggcagtctt gttagaagcg aatatggagc aaacacataa
     9721 ggatgtgcaa aaaaaaaagt tttatcagct tacgccatct gaacggcgca gtcaattaat
     9781 agaaaaaaat gtattgacac aagaaactgc gttgattttt caggaacaaa cactttctga
     9841 agagctctcc gatcacatga tcgaaaacca agtgagtgaa gtggaaatcc caatgggcat
     9901 cgcgcagaat tttcaaatca atggtaagaa aaaatggatt ccgatggcaa cagaggaacc
     9961 atctgtcatt gcagctgcaa gtaatggtgc aaaaatctgt ggaaatatct gcgcagaaac
    10021 acctcagcgg ctgatgcgag ggcaaatcgt tctatcagga aaatcggagt atcaagcagt
    10081 gatcaatgca gttaatcatc gaaaagaaga gctgattctt tgtgcaaatg aaagttatcc
    10141 ttcaatcgtg aaacgcgggg gcggtgttca agatatctct actcgggaat tcatggggag
    10201 tttccatgca tacttatcta ttgatttttt agtggatgta aaagatgcaa tgggcgctaa
    10261 catgatcaac tcgattcttg agagtgtggc aaacaagtta cgggagtggt tccctgaaga
    10321 agagattcta ttcagtattt taagtaattt tgctacagaa tcattggctt ctgcctgttg
    10381 tgaaatccca ttcgaacgct tagggagaaa caaagaaatc ggtgaacaaa ttgccaaaaa
    10441 aatccaacag gcaggggaat atgcgaagct tgacccttac cgtgcagcaa cgcacaacaa
    10501 agggatcatg aatggtatag aagctgtagt ggcagctaca ggaaatgata cacgtgcggt
    10561 tagcgcttcg attcacgcct acgcggcaag aaatggatta taccaaggat taacagactg
    10621 gcagatcaaa ggggataaac tagttggaaa actaacggtg cctttggctg ttgccacagt
    10681 aggcggagct tccaatatcc tgccaaaagc aaaagcatct ttagctatgt tagatattga
    10741 ttcagccaag gaactagcac aagtaattgc tgcagtaggg ttagctcaaa acctggctgc
    10801 tttgcgtgca ttagttacag aaggaatcca aaaaggccac atgggacttc aagctcgttc
    10861 attagcgatc tcaattgggg ctattggtga ggaaatcgag caagttgcga aaaaattacg
    10921 tgaagcagaa aagatgaacc agcagacagc tatacaaata ttggaaaaaa tccgggaaaa
    10981 ataaaaaagc aatatcttta gaagaataaa gcaagattta cagttatttt attta
//
LOCUS       DACDAF010000088        10574 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.091, whole genome shotgun sequence.
ACCESSION   DACDAF010000088 DACDAF010000000
VERSION     DACDAF010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10574)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10574)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10574
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.091"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            12..84
                     /locus_tag="IVZ69_002217"
     tRNA            12..84
                     /locus_tag="IVZ69_002217"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="IVZ69_002218"
     tRNA            88..160
                     /locus_tag="IVZ69_002218"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="IVZ69_002219"
     tRNA            168..249
                     /locus_tag="IVZ69_002219"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="IVZ69_002220"
     tRNA            267..339
                     /locus_tag="IVZ69_002220"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="IVZ69_002221"
     tRNA            351..422
                     /locus_tag="IVZ69_002221"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="IVZ69_002222"
     tRNA            439..524
                     /locus_tag="IVZ69_002222"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="IVZ69_002223"
     tRNA            535..608
                     /locus_tag="IVZ69_002223"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="IVZ69_002224"
     tRNA            618..691
                     /locus_tag="IVZ69_002224"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="IVZ69_002225"
     tRNA            711..783
                     /locus_tag="IVZ69_002225"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="IVZ69_002226"
     tRNA            811..884
                     /locus_tag="IVZ69_002226"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="IVZ69_002227"
     tRNA            898..971
                     /locus_tag="IVZ69_002227"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="IVZ69_002228"
     tRNA            995..1084
                     /locus_tag="IVZ69_002228"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="IVZ69_002229"
     tRNA            1097..1170
                     /locus_tag="IVZ69_002229"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="IVZ69_002230"
     tRNA            1189..1264
                     /locus_tag="IVZ69_002230"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="IVZ69_002231"
     tRNA            1266..1336
                     /locus_tag="IVZ69_002231"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="IVZ69_002232"
     tRNA            1350..1423
                     /locus_tag="IVZ69_002232"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="IVZ69_002233"
     tRNA            1448..1535
                     /locus_tag="IVZ69_002233"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="IVZ69_002234"
     tRNA            1557..1628
                     /locus_tag="IVZ69_002234"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="IVZ69_002235"
     tRNA            1651..1740
                     /locus_tag="IVZ69_002235"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="IVZ69_002236"
     tRNA            1753..1826
                     /locus_tag="IVZ69_002236"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="IVZ69_002237"
     tRNA            1845..1917
                     /locus_tag="IVZ69_002237"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="IVZ69_002238"
     tRNA            1921..1993
                     /locus_tag="IVZ69_002238"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="IVZ69_002239"
     tRNA            1998..2068
                     /locus_tag="IVZ69_002239"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="IVZ69_002240"
     tRNA            2081..2154
                     /locus_tag="IVZ69_002240"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="IVZ69_002241"
     tRNA            2166..2237
                     /locus_tag="IVZ69_002241"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     gene            2503..3696
                     /locus_tag="IVZ69_002242"
     CDS             2503..3696
                     /locus_tag="IVZ69_002242"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HAP8184281.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="IVZ69_002243"
     CDS             3826..5298
                     /locus_tag="IVZ69_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8184282.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="IVZ69_002244"
     CDS             5381..6169
                     /locus_tag="IVZ69_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HAP8184283.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="IVZ69_002245"
     CDS             complement(6236..6904)
                     /locus_tag="IVZ69_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HAP8184284.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="IVZ69_002246"
     CDS             7019..8731
                     /locus_tag="IVZ69_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8184285.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10506
                     /locus_tag="IVZ69_002247"
     CDS             8734..10506
                     /locus_tag="IVZ69_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HAP8184286.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         3033 a         1926 c         2453 g         3162 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 agttaaatta aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt
    10561 ttttataagg ggca
//
LOCUS       DACDAF010000089        10546 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.092, whole genome shotgun sequence.
ACCESSION   DACDAF010000089 DACDAF010000000
VERSION     DACDAF010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.092"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            36..260
                     /locus_tag="IVZ69_002248"
     CDS             36..260
                     /locus_tag="IVZ69_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HAP8184287.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(465..785)
                     /locus_tag="IVZ69_002249"
     CDS             complement(465..785)
                     /locus_tag="IVZ69_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HAP8184288.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(933..3167)
                     /locus_tag="IVZ69_002250"
     CDS             complement(933..3167)
                     /locus_tag="IVZ69_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP8184289.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            3646..3912
                     /locus_tag="IVZ69_002251"
     CDS             3646..3912
                     /locus_tag="IVZ69_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HAP8184290.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            3912..5639
                     /gene="ptsP"
                     /locus_tag="IVZ69_002252"
     CDS             3912..5639
                     /gene="ptsP"
                     /locus_tag="IVZ69_002252"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HAP8184291.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            5770..6849
                     /locus_tag="IVZ69_002253"
     CDS             5770..6849
                     /locus_tag="IVZ69_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP8184292.1"
                     /translation="MLYYISEGGRKVKVLLYFESEKMLAKSGIGRALDHQKRALTEVG
                     ISYTLDEKEDYDILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQL
                     SPIVKKYLVGLYQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQ
                     KFREYFKLSPDQKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIR
                     KIVKEDHPENVLFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVR
                     DIPVYNGWLEDSKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEE
                     LKNVYESVLNEKVSSKLKKVNQVKD"
     gene            6866..8089
                     /locus_tag="IVZ69_002254"
     CDS             6866..8089
                     /locus_tag="IVZ69_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HAP8184293.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            8178..9065
                     /locus_tag="IVZ69_002255"
     CDS             8178..9065
                     /locus_tag="IVZ69_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HAP8184294.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            9151..9381
                     /locus_tag="IVZ69_002256"
     CDS             9151..9381
                     /locus_tag="IVZ69_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HAP8184295.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(9438..10403)
                     /locus_tag="IVZ69_002257"
     CDS             complement(9438..10403)
                     /locus_tag="IVZ69_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HAP8184296.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
BASE COUNT         3418 a         1839 c         2135 g         3154 t
ORIGIN      
        1 gcgtacatat gattaaagaa aggagagtgt gacacatgga aacagaatgg caaagacgtg
       61 aaagaaaaaa acagaaaaaa gaagagatgt tacgattatg tcgattatta gatgtaaaag
      121 actgggacaa aaacgagcaa attgcacaaa aagtacgatc aatcatccat aaagaggaaa
      181 aagttaaaaa taaagacacg cgtagaactg aaaatgaaaa gagaaaagta caaaagaaaa
      241 gagaaaaatc aaaaagctag aaagaaaaag aggctgagac agaagcgttt aactccaaga
      301 aataagctgg aattcacaaa aatttgaaaa gcaattttcg tgaatttcag cttatttccg
      361 aaggagttgc ttctgctttc gccgtttata cgtgtttaga gcgtgagaca aaagtgttct
      421 ttacttttgt cccacgctct ttaattatta tgttcaaaat ttgtttacac ggctaatgta
      481 gcgcctaatt catgttttgg aatcgagatt tcaacaaggc ctgccaattc gattactttg
      541 atttcatcct cgtggtaaac ggcgtctttg attttatcta agaaataatt tttagcatct
      601 tcgatttctt tcggctggat tttacgtttg tcattgatca gcagaatttc attatgttca
      661 ggggcttcag tgtagacaat agtggtattt ccggctgtgt agaccttgac tagatgggca
      721 tcagtgtttt caagctggtt taatacaaga cgggaatggc tgtttgttac atttaccaat
      781 ttcatggcgc tcacctcttt tatgtatttt taattgcttg tttctcttat tataatttct
      841 tttttataaa atgaacagta ttttgacttt tctgaaaaaa gaatgagacg gcatttctca
      901 aagaaatacc gtctcacgct ataaaactgg atttattcag ccgtttcttc ggctgattct
      961 ttagccaaac gttctggttt agaagtaacg atgatttttc catctttatc cagttttgct
     1021 ttcaactcat ggatagaagg gtgatcaaga taaaattcag cgataccatc ttcgatttgt
     1081 tcttggatcg tgcgtcgaag aggacgagca cccatagatg gatcatagcc taagtcaact
     1141 aatttttctt tgacattcgt aggaacttcg atgtgaagtt gctgtgctgc cagcatttgg
     1201 ttgacatcgt ctagcattag tgtgacgatt gtcatcaagt tttcttttga taatgcactg
     1261 aattcgatga tcccgtcaaa acggttcaga aattctggtg taaagtagtt gtttaattgg
     1321 ttcaatacag aacgagtaac accttcgcgt gccgcaccaa aaccaacgtt tgcttctact
     1381 ttaccagttc cggcattact tgtcataatg atgatcgtat ctttaaagct gaccgttctt
     1441 ccttgtgcat ctgtcaatcg accatcatct aagatttgca agaacatatg caaaacatct
     1501 ggatgagctt tttctacttc atctaacaag acaagactgt aaggatttct ccgtactttt
     1561 tctgttaatt gaccagcttc ttcgtatccg acataacctg gaggagaacc aatcaattta
     1621 gagacactat gtttttccat atattcagac atatcgaaac gaatcattga atcttgtgaa
     1681 ccgaatagtt cgtaggcaag ttgtttcgca agctctgttt tacctacacc agttggtcca
     1741 acaaataaga aggagccgat tggacgattc tgtttgttta atccaacacg gtttcggcga
     1801 atcgctttcg ctactcgatc tacagcgtta tcttgtccga tgacatgagc tttcaagtca
     1861 tctgctaagt ttttcagttg tgtctgttct ttttctttta attcacccac tggaatacct
     1921 gtccgttgtt caacgatttt ttccatatct ttttcggtaa tcacaggtgt ttcctcttca
     1981 gtgagctgac gttctttcat tttttgaagt ttattgatct gatcgcgata ataagctgct
     2041 ttttcgaaat cttcttctcg agaagctaaa actttttgtt cttctgcttc ttgcagtttt
     2101 ttctcgattg ttttaggatc aacgatttgg atcgtcaagt ttttcttaga acctgtttca
     2161 tctagcaaat cgatggcttt atccggcaag aagcgatctt ggacgtaacg attggataaa
     2221 gttgcggctg cttcgatggc ctcatcagta tattttacat gatgatagtc ttcataacgt
     2281 ttttgcaaac ctttcaaaat actgatcgtt tcttcgacag ttggttcatc tacccgtaca
     2341 ggttgcatac gacgttctaa agcagcgtct ttttcgatga tgcggtactc atttaaggta
     2401 gtagcaccaa ccatttgcaa ttctcctcga gctaaagctg gttttaaaat attaccagca
     2461 tccatatttc catcaccagc agaaccagca ccgacgattt cgtgaacttc atctatgaat
     2521 aggatcacat tttctgcttg acggatctct tcaatcaatt tttgcatacg ttcttcaaat
     2581 tgtcctcgta taccagtacc ttggactaaa gatacgacat ctaaacgaat gacttctttg
     2641 tccattaatt tttgcggtac atcaccatct acgatttttt gtgctaaacc ttcaacaact
     2701 gctgttttac caacacctgg ttctccaatc aagacaggat tgttcttggt tcggcgattt
     2761 aaaatttcaa tgactcgttt gatttcgtca tcgcgtccga tcacaggatc gatatcacct
     2821 tgtcgtgctt gttctgtgat attgattccg tattctccca ataaaccttc tgtattgcct
     2881 tgaggtggct gaccaccatt gaagttgttg tttccgccaa attgtgttgg tggtgtttgc
     2941 tcataatttc cttgctgttg catttggcga gacatggaac ggaaaagatc gtccaaactg
     3001 ccaaatccaa atggatcatt ttgggccata ttagtcagac ctccattttg ttgatttttg
     3061 attttttgat aacagctctg acagtaatcg agttgtgtcc gctgaccatt gacagtggca
     3121 tacaagtgaa tcgttgcctc attcttgccg cagttttgac aaagcatgaa tcattcacgt
     3181 cctttcacaa aaatgggtac atccatattt tacatctcgt ttttcatgag gtaaaagaat
     3241 aacccctagt tttttaagag atttatgagg tagaaaaggt gaaatctcta ttgaccattc
     3301 ctgacctttg actcttatta tactaaaaat aaaaagggaa gcaagtaatt cgtttcatat
     3361 gaaaacaaag agggtcaaag gaaagaatga taaacgtcag gagaagagaa agcgacaaga
     3421 aaaaggaaat aaacacgttt gttataaaat gtgaagaaaa ggatgaaaaa gaatccggaa
     3481 taatttgaat acttttatct gaaattgaat gaaaactgtt gtatctaacg aaaaaaaatg
     3541 ttaatcttta cagatgaaag ggtggcattt gttaggattc tctgaattac taaaaaagaa
     3601 aaccctcaca taaaaacaac actcacttaa aggagaccga ttaatatgga aaagaaagaa
     3661 tttcacgtag tagcagaaac tgggatccac gctcgtccag ctacactatt agtacaaaca
     3721 gcaagcaaat ttaactctga tgtaaactta gagtataaag gtaaatcagt aaacttgaaa
     3781 tcaatcatgg gcgttatgtc tttaggtgta ggtcaaggtt ctgatgttac tattactgca
     3841 gaaggtgctg acgaagctga tgcaatggca gcaatcgttg aaacaatgaa gaaagaaggc
     3901 ttatctgaat aatggttgaa atgctaaaag ggattgccgc tagtgacggt gtagccgttg
     3961 caaaagctta cctgctagtt caaccggatt taacattcag taaggcaaca gtagaagata
     4021 ctgcggctga agaagctcgt ttggatgctg cattagctaa atctactgaa gaattgcagc
     4081 aaattcgtga aaaagcagcg caaagcttag gtgaagcaga agcgcaagta tttgatgccc
     4141 atttgatggt tctttcagat ccagaaatgg taggtcaaat caagcaaaat attaaagaca
     4201 acagcgtaaa tgctgaatca gcgctaaaag aagtaacgga tatgtatatc ggtatgttcg
     4261 aagcaatgga agataatgct tatatgcaag agcgtgctgc agatattcgt gacgttgcta
     4321 aacgtatttt agcgcactta ttaggcgtta ctttaccaaa tccatcaatg atcaacgaag
     4381 aagtggtcgt tgttgcacat gacttgactc caagtgatac agcacaatta gatcgcaatt
     4441 ttgtaaaagc gtttgtaaca gacattggtg gacgtacttc acattctgct atcatggcac
     4501 gttctttaga aattccagca atcgttggga caaaagaaat tactgctaaa gtcaaagaag
     4561 gcgatatttt ggctgtcaac gggatcgaag gcgatgtaat catcgatcct acagatgaac
     4621 aaaaagctga atttgaaaaa gcaggtgcag attacgcagc acaaaaagca gaatgggaaa
     4681 aattaaaaaa tgcagaaact gtcacagctg acggcaagca ttttgaatta gctgcaaaca
     4741 tcggaacacc aaaagatcta gttggtgtcc ataataatgg tggagaagca gttggtctgt
     4801 accgtactga attcctgtat atggattctc cagacttccc aacagaagat gaccaatatg
     4861 aagcttacaa agctgtatta gaaggtatgg aaggaaaacc tgtagttgtt cgtacaatgg
     4921 acatcggtgg agataaagaa ctaccatatc tgcaattacc tcatgaaatg aatccattct
     4981 taggatatcg tgcattgcgt atcagtttat ctgaacaagg cgacgaaatg ttccgtacac
     5041 aaatgcgtgc attgcttcgt gcatctgttc atggtaattt acgtatcatg ttccctatgg
     5101 tagctacact caaagaattc cgcgcagcaa aagcgatctt tgaagaagaa aaacaaaaat
     5161 tgataagtga aggcaaggaa gtatctgata cgatccaagt cggcatcatg atcgagattc
     5221 cagcagcagc agtcttagca gacaagtttg caaaagaagt agatttcttc tctgtaggta
     5281 cgaacgattt gattcaatac acaatggcag cagaccgtat gaacgaacgc gtttcttact
     5341 tgtaccaacc atataaccca tcaattttac gtttgatcaa aaatgtaatt gatgcagcac
     5401 acgctgaagg aaaatgggca ggtatgtgtg gagaaatggc tggagatcaa acagctgttc
     5461 cattgctagt aggtatgggt ctagatgagt tctcaatgag tgcgacatct attcttaaaa
     5521 cgcgtagttt aatgaaacgc ttggacacag cgaaaatggc tgaacttgct gatcgtgcat
     5581 tgaaagaatg cgatatgatg gaagaagtcg ttgaacttgt tcatgaatat gtaaaataaa
     5641 caacgtatca aaagctggtg tggcttgtaa aagagctacg ccagtttttt tgttcttttt
     5701 taagaaaacg tttttgtcag taagaataga caaaaatagg gcttaagttt gagtgacagt
     5761 ttgtaggcta tgttatacta tataagtgaa gggggacgta aggtgaaggt attattatat
     5821 tttgaaagtg aaaagatgct tgcaaaatct ggaatcgggc gtgcgcttga tcatcaaaaa
     5881 cgtgctctga cggaagtcgg tatctcttat acactagatg aaaaagaaga ttatgacatc
     5941 ctgcacatca atacatacgg aatcaatagt cataatatgg tcaataaagc cagaagagaa
     6001 ggaaaaaaag ttgtctatca tgcgcattct acagaggaag atttccgaaa ttcctttatc
     6061 ggatcgaacc agctttctcc tatcgtaaaa aaatatctgg taggattgta ccaaaaagcg
     6121 gactatctga tcacgccaac accttattca aaacagttgt tggaaagcta tggtatccgt
     6181 gtgccgattc aagctatttc caatgggatc gacttagaga aatatcaccc tgatccaatg
     6241 aaagaacaaa agttcagaga atatttcaaa ctgtctccgg atcaaaaagt aatcatttgt
     6301 gtcggtttgt ttttcgaacg taaaggaatc attgatttcg tagaaattgc taagaagatg
     6361 cccgaataca catttatttg gtttggtcat gttcccatgt actcgattcc tcggaacatc
     6421 cggaaaattg taaaagaaga tcatcctgaa aatgtcctgt ttcctggtta cattcgtgga
     6481 gagatcatag aaggtgcgta ttcaggtgca gatctattct ttttcccttc ttatgaagag
     6541 acagaaggga tcgttgtttt agaagcttta gcaagcaaac aaaacgtact tgttcgagat
     6601 attccagtgt ataatggctg gttagaagat agcaagaact gctatatggg gaagacaaac
     6661 gaagaattta tccgactgat ccaacagatt accaatcaag aactaccgag tacgacacaa
     6721 gccggttatc aaacagcaaa agagcgaagt atcaataaaa tcggtgaaga acttaaaaat
     6781 gtatacgaaa gtgtactgaa tgaaaaagtc tctagcaaat taaaaaaagt aaatcaggtc
     6841 aaggactagt ttggaggcga aaaacatgaa aatcggcttt tttaccgata cctactttcc
     6901 gcaagtcagc ggagttgcta catcgatcaa aacattaaaa caagaattag aaagacatgg
     6961 gcatgaagtc tatattttta caacgaccga tcctaatgcg gataagttgg aaaaagatgt
     7021 gattcgaatg ccaagtgtac catttatttc tttcaaggat cgaagagttg ttgttagagg
     7081 catgtggtat gcttatttgg ttgccaaaga actagaacta gatcttattc atacccatac
     7141 agaattcgga gcagggatac ttgggaagat ggtagctaag aagttgaaaa tacctctgat
     7201 ccatacttac catacgatgt atgaagacta ccttcattat atcggtaaag gaaaagtgat
     7261 caggcaatcc catgtaaaat acttgtctag attatttgca aatcatacga caggtgtagt
     7321 ttgtccaagt gaacgtgtta ttgatacatt acgcagctat ggtgtaatag caccgcttcg
     7381 cgtgattcct actggtatcg acattgaaaa attcaaacgt tctgatatca ctcagcagga
     7441 tatcagcaaa ttaagggagt cactaggtct tcaggaaaac catttgatga ttctttcttt
     7501 aagcaggatt tcttatgaga aaaatatcca agccttgatt aatgggtttc ctcaggtcat
     7561 ctccgcttat cctaacgcca gattagttat cgtaggaaaa ggaccttatg tagaagagtt
     7621 agaggaattg atctcagaac tgcagttaga agaatttgtg cagttcacag gagaagtgga
     7681 caacaatgat gtagcacttt attataaagc ggcagattat tttgtcagtg cttctacttc
     7741 agaaacacaa gggcttactt atacagaagc gatggcagcc ggaacacctt gtgtcgtgga
     7801 aggaaatgct tatttgaacc gattgttcga tcatccttca ttagggaaaa cttttgaaac
     7861 cgacgaagac tttgcaccag cacttattga ttatatttcc agtgaagttc ctaaagatcc
     7921 aaaagtttta gaagctaaac tttatgatat ttcatctaca catttcggcg aagctatgat
     7981 cgaattttat caagacatgg ttgtttatca tgaagaagag atgcgaagaa aagaagaaga
     8041 agactcgatt gaacgaatca aaataaaatt aaattcattt aaaagataaa attcaaacat
     8101 tttttatgaa aaaatccttg tttctagcgt atactagcat agaagcaagg atttttgatt
     8161 tttaggaggt cgaaaaaatg aaacttggtt ttatcggaac aggcgtcatg ggaagtgctg
     8221 tcgcacgcca tctactagaa gcaggacacg aagtagctgt ctataatcgg acaaaagcaa
     8281 aagctgatcc tttagtaaca gaaggagcta tctgggcaga tacaccaaaa gcggtagcag
     8341 aacaaagtaa tattctcttt acaatggtag gttaccccaa agatgtagaa gaaatctact
     8401 atggacagtc ggggattttt tctgcagata tctcaggaca tattttagtt gatttgacta
     8461 caagtacacc aagcctggca gaaaaaattg caaaaacagc aaaagaaaaa ggcgcagatg
     8521 cgttagatgc accggtatcc ggtggtgact taggagcaaa gaatggtaca ctgacgatca
     8581 tggtcggtgg agaagaagcc gtttatgatc aagtactgcc tttattcaaa gaatttggta
     8641 cgacatttac attgcatggt tctgctggga aaggtcagca tacaaaaatg gctaatcaga
     8701 tcatgattgc aggtacgatg acaggaatga cggaaatgct tgtctatgca caaaaaaacg
     8761 gacttgattt aaagaaagtg attgagacgc tttcaggtgg aagtgcagct aactggtctt
     8821 taagcaatta ttctcctcgt attttaaaag aagattacac acctggtttt tttgtcaaac
     8881 attttatcaa agatttaaag attgcattag aagaagcaga aaaaatggat cttgtattgc
     8941 cagcaactac ccaagcattg aaactatatg aagagttggc agataaaggt tttgagaatg
     9001 acggaaccca agctttgatc aaactttggt ggcctgaagg aaaaatacca gaaaaaaaat
     9061 cataaaaaac gagttttttt agagaaaatc aatgcaagta ggctatgctt ttgatacaat
     9121 ataacagaaa taagaaaagg aggacctccg atgacacatt cacaattagt cgcaatcata
     9181 aaacgactgg aggctatggt cgagtcagca gataatgaac tgcaagttcg ccgttttgaa
     9241 aaagaaggcg tagagaagtg tacagtaact tatgataaag cgaccgatac atttgaatta
     9301 actgaaacag atactcatca gcaatacgaa tttgataata tcgatatcgt agcgatggaa
     9361 atctatgact taatccaata aattttagga taattgacat ttgaagttga agatgcctaa
     9421 aagaagccga gaagcaacta atttagttgc ttttcagctt cttttttgtt taacagttca
     9481 atttcaaact gttctttttc taattttttg cggtaactga tcaagatttg tacaggatcg
     9541 atttcttctt ttgacaattg acgtttcaaa gataaatgag cttctttctt ttcataatag
     9601 aagtcaggag aaacgtcacc agaggtaatc attgtttctg caagttgacc ataacaaacg
     9661 aggtagtgct ttttctgact ctcatctgct gctaatggca tgctgaaggt gagcgatggt
     9721 gttcttaaaa actgcttttg ttcctggatc cgtctaataa aataagtaac taattcgata
     9781 tctttttgaa gcataccggc tttttcgaaa ttcaactgat agatgaaatg ttgttgtctt
     9841 tttttcaagt aagtcagtag ctttttattt cggccttgaa acagcccttg gagttccttt
     9901 tttttctgtt caaaagtcat ttcctgtagg tcaggaagct ggactcgcaa agctaacaaa
     9961 ctaatttcag acaaccaagg catttgataa gtttcttcca ttatacgcaa aatagacggc
    10021 atttttttat agagacgaaa aggcccgtat gttcgagccg taggagtatc tgttaataca
    10081 aatcccttat tggtaatatg tacataatta taattactga aataattcat ttgtcggtta
    10141 taaaaaggac ggtaatgttg gatcaattga cactcgagca ataaagcatc taattccgtg
    10201 tctactacga cgaaatcaaa atctgttata tgatgaatca tacgtaatac tttttttgaa
    10261 tgctgtttat tctgatgaaa atagctgctt actctatttt tgagccgttt tgctttacca
    10321 acatagatga ccttaccatc tcggtctttc ataagataga cacccggcag catggggaga
    10381 gttttcattt tttcttttaa cataggatct ccttttacgc tttgaataaa aagactataa
    10441 caaattttga aataatggac aagttttagg gaattctata gttctgttca cagaaaatac
    10501 tttgataatc aaaatatgtg agatagatga tttttctaat aaaaga
//
LOCUS       DACDAF010000090        10497 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.093, whole genome shotgun sequence.
ACCESSION   DACDAF010000090 DACDAF010000000
VERSION     DACDAF010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10497
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.093"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..361)
                     /locus_tag="IVZ69_002258"
     CDS             complement(<1..361)
                     /locus_tag="IVZ69_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAP8184297.1"
                     /translation="MATVWMGLALVGNTFSPNSAMEGQGVIDVLTHIYTTGPAEYAKS
                     ILVNVFFGAFFGRVLVDSGIAATLIRKVVELGGDKPRITMSLLCIVTAVIFMSMTGIG
                     PVISIAVIVLPILMSLGI"
     gene            complement(713..1072)
                     /gene="rplT"
                     /locus_tag="IVZ69_002259"
     CDS             complement(713..1072)
                     /gene="rplT"
                     /locus_tag="IVZ69_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HAP8184298.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            complement(1125..1325)
                     /gene="rpmI"
                     /locus_tag="IVZ69_002260"
     CDS             complement(1125..1325)
                     /gene="rpmI"
                     /locus_tag="IVZ69_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HAP8184299.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            complement(1397..1921)
                     /gene="infC"
                     /locus_tag="IVZ69_002261"
     CDS             complement(1397..1921)
                     /gene="infC"
                     /locus_tag="IVZ69_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HAP8184300.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            2241..2873
                     /locus_tag="IVZ69_002262"
     CDS             2241..2873
                     /locus_tag="IVZ69_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP8184301.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGNQSYLDAKN
                     MVLRESHIQKLTMQKTGLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTTIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(2875..3780)
                     /locus_tag="IVZ69_002263"
     CDS             complement(2875..3780)
                     /locus_tag="IVZ69_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP8184302.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWEIALIISLVLSIWMLIALWRRIR"
     gene            complement(3865..4518)
                     /locus_tag="IVZ69_002264"
     CDS             complement(3865..4518)
                     /locus_tag="IVZ69_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HAP8184303.1"
                     /translation="MIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFYAN
                     PEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEVCV
                     YDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYDYY
                     KELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVSI"
     gene            4840..5784
                     /gene="mvk"
                     /locus_tag="IVZ69_002265"
     CDS             4840..5784
                     /gene="mvk"
                     /locus_tag="IVZ69_002265"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HAP8184304.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            5777..6754
                     /gene="mvaD"
                     /locus_tag="IVZ69_002266"
     CDS             5777..6754
                     /gene="mvaD"
                     /locus_tag="IVZ69_002266"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HAP8184305.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKKGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            6767..7852
                     /locus_tag="IVZ69_002267"
     CDS             6767..7852
                     /locus_tag="IVZ69_002267"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HAP8184306.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            7849..8913
                     /locus_tag="IVZ69_002268"
     CDS             7849..8913
                     /locus_tag="IVZ69_002268"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HAP8184307.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKDPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAQEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(9162..9965)
                     /locus_tag="IVZ69_002269"
     CDS             complement(9162..9965)
                     /locus_tag="IVZ69_002269"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HAP8184308.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIRDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(9985..10290)
                     /gene="kduI"
                     /locus_tag="IVZ69_002270"
                     /pseudo
     CDS             complement(9985..10290)
                     /gene="kduI"
                     /locus_tag="IVZ69_002270"
                     /inference="COORDINATES: protein motif:HMM:NF002091.0"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
     gene            complement(10272..>10497)
                     /locus_tag="IVZ69_002271"
     CDS             complement(10272..>10497)
                     /locus_tag="IVZ69_002271"
                     /inference="COORDINATES: protein motif:HMM:NF018513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="TRAP transporter large permease subunit"
                     /protein_id="HAP8184309.1"
                     /translation="LWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKIIKEAIPSLLLI
                     VIIIGGILTGIFTAVEASAIAVIYKWVIRF"
BASE COUNT         3107 a         2220 c         2008 g         3162 t
ORIGIN      
        1 aaatacctaa tgacatcaag atcggcaaca caataactgc aatagaaatc actggtccga
       61 ttcctgtcat cgacatgaat ataacagcgg ttacaataca tagtaagctc atcgtgattc
      121 ttggcttgtc ccctccaagt tcaactacct ttcgaatcag ggtagctgcg attccgctat
      181 ctactagaac acgcccgaaa aaggcaccaa agaagacatt taccaagatc gatttggcgt
      241 actcagctgg ccccgtcgta tagatatgcg tcaacacatc aattactcct tgcccttcca
      301 tcgccgagtt tggtgaaaac gtgtttccga ctagcgctaa tcccatccat acagtagcca
      361 tgatgacaaa agccgaccat caagttgtag ccttttacac agtaccagac catgaaaaag
      421 aatgagataa ctaacaaaat accaataata atatcactca tgttattcct ccgtccattt
      481 tgtttttctg ataagcaaac taatatatca gtcaaactca ttctaactta tgtagttagc
      541 gctttcatta aaggatgacc ataaatgttc agttttcaat taaaaaacct taattatgtt
      601 attttagact tatacgttat tgtcctgttt catttgatgg aggattgtaa ataaaaaaag
      661 aggaaagaac ataacttttc gttatcttct ttcctcttta taattgttta gcttatttag
      721 ccaaagcttc ttttgcttgg tcagccaatg cagtaaatgc tgctgcatcg ttaacagcca
      781 agtcagctaa cattttacgg ttgatgtcga tttcagcaac tttcaaaccg tgcattaatt
      841 ttgagtagct caagccattc atacgagctg ctgcgttgat acgagcaatc cacaatttac
      901 ggaagtcgcg tttcttttga cgacgatcgc gatatgcgta gttgtatgaa ttcattactt
      961 gttcttttgc tgttttaaat aaagtgtgtt ttgaaccgta gtaacctttt gctaatttta
     1021 gcactctttt acgacgttta cgagttactg ttccaccttt aacacgtgcc atgtataatt
     1081 cctcctaata aaaataaatc ttcagattct gttatttgta cttcttattt catttttgct
     1141 agttgttggc gaatacgttt gaagtcgcca ctagaaacca tgcttgcttt acgcaattga
     1201 cggcgttgtt tttttgtttt gccgtggaaa cggtgacttg taaacgcgcg gaagcgtttc
     1261 aatccgcctt taccagtacg tttgaaacgt tttgctgatc cgcggtgtgt tttttgtttt
     1321 ggcatgacta tatttcctcc tcaaaatctt tcgttatccg actatcggct gtccaacagc
     1381 cagttagtca ttcaaattac ttactgtcgt ttttcggtgc cagcgtcaag aacatgctgc
     1441 gtccgtccat tttcgctttt tgttccactg ttgcaatatc cgcagtttct tcagctaagc
     1501 gattcaagac tttttgacca atttctttat gggtaatggc acggcctttg aaacggatag
     1561 aagctttcac tttatcgccc ttttccaaga acttacgtgc attacgaagt tttgtattga
     1621 agtcattcaa gtcgatcgta ggacttaagc gaacttcttt tacattgatc actttttgtt
     1681 ttttacgcgc ttcgcggtct ttcttttgtt gttcgaaacg gtatttaccg tagtccatga
     1741 ttcgcgcaac tggtggtttc gcaccagggg caactaacac aagatccaag tttgcttgtt
     1801 ctgcaatatt caatgcttct gcttttgtct taactcctaa ttgctcacca tctgaaccga
     1861 tcaatcgtaa ctctcgtgca cgaatgccgt cgttaaccat catatccttt gctatggtca
     1921 ttcacctcca aatattatga gagaaagaaa agcttaccga ataaacggca ataaaaaaac
     1981 gagttctctt acagaacccg cgcgtacttc acctaataga accagtgaaa actatctagc
     2041 ccagtgacat tatcaactaa ggcgagaagc gggtgcttct gcttttattt ctcaaccatt
     2101 atagtatagc aaaaactaat ctttttgtca atgtttttca tacagtttgt cttccttttc
     2161 tgaaaatgat tagattagca ggctttctag cagtgattcc cgcttctttg ctatactaaa
     2221 gaaaaacgag gtgaacccac atgaaaaaaa tcgaacctat tccaccttct cttcctcttc
     2281 ttacaaaggg agagttttat ttagaagatg aggagatctt ctctggtctt ctgatcaacg
     2341 gaggtaacca aagctatctc gatgccaaaa atatggtatt aagagagagt catatccaaa
     2401 aacttacgat gcaaaaaaca ggtttacgtc attttgaatg cagtaatgtc atttttgaaa
     2461 aatgtgattt ttccaatctg gagtggattg gtggcagttt ccaccaagtc gtgtttcatc
     2521 aatgtaaatt aacaggtacg aattttgccg aaagttatct tcgagactgt actttcactg
     2581 attgtattgc ttcgatggct tcctttagta gtacaaactt gaaagctgtc tccttcgatc
     2641 attgtcaatt agaagacagc gaattttatg aggtcacttg gaaaaacctt tttttgtctg
     2701 acaatcagtt aaccggttcg aactggtttc gaacttctct gaagggatta gactttacga
     2761 ctaatttctt cacaacaatc gctttatctc aagattcttt ggcgggacta atcgtcaatc
     2821 aagagcaagc acttgtgatc gcccaagccc ttggtttgca gatcaaagac tagatcaacg
     2881 aatccgccgc cacagtgcaa taagcatcca aatagataag accaaactga tgatcaaggc
     2941 gatttcccat ccgaaaacgg aatgggtaaa gggtaactgg agattcattc cgaagaatcc
     3001 tgtcacaata gttggaacgg tcaagatcag cgaccagacc gtcaaaaatt tcatcgtgtc
     3061 attcaagttg ttattcagca aattattata agtgccagag agctggtcta aaatctgcga
     3121 agctaagttc gtcatttcaa ctgcttgtcg tgcttcgatc agtgcatcgt ccaactcttc
     3181 tttttccttt tctgacaact tgcgataaat agccagtgcc ttgatttgtt ctaaaagtac
     3241 tacattttgt tttgttcctg taactaagta aaccaaaccg atctctaaat ctgaaagttg
     3301 cagcagattc ttgttcgttg ttttttctct taatttcaga ttaagccgct gacgttcact
     3361 attcacttcc tcgattaaag gaaaaaagga atcagaaatc aaaaacaatg tacgaaacaa
     3421 taaactgtat acactcatgt ctggcatccg ttccaaaagc gatcgaatta gtcgaatcac
     3481 gtactcggta ttcggcgtgg taaatgtaaa caaaccgtct tcttttaaaa taaaagcgat
     3541 aggactagtt tcataatgat tatcgacttt ttgctggtgc ggaacatttg atacaagcag
     3601 taacgcttca tcaaaagaat cgtactctac gcgcgcccgt tcatttttat ctagagaata
     3661 agtcagcatc tcgtcactaa tgccatattc ttcttttaag tttttaacag ctagcacatc
     3721 gttttgctgt acattgatcc aaaaattacg gtcttgatta aaatagtgtt tttcccgcat
     3781 actctatcct cctgacattt gtttccagta taaagaaaaa agtcgctcaa ataaaggttt
     3841 accctttatt tgagcaactg taaatcaaat ggatactttg gtttggcgaa tctctgctaa
     3901 tttttcttcg atcattttca agacttcttc ttttgcttga ggatcttcca caaaattata
     3961 gcggtctcca tcgatttgga tttttggact ttctttgtat tcttcatacc attgatcata
     4021 acgtctgttc aattctttgt aataatcgta tagacttggg tcaaaggaca attgttcata
     4081 cgaacgacca cgtttttcga tacgctctaa catcgtatca aaagatacac gaatatgaac
     4141 taataaatcc ggatgttttt tatgggcagc atagggaagt tcttccatca tgttttccag
     4201 cagttcatca tacacacaaa cttctgtttc tgttgctctt cctagatctg catttagatg
     4261 gaaaagcagt gaatcttcat aaatcgaacg gtccaataca ttattgtcat ctttcattgc
     4321 ttgtttgatg cttgcaaaac gtttattcaa aaaataaatt tgcagcaaaa aagcatactg
     4381 ttcagggttt gcataaaata agggcaagac ttcattatca tcaatcgatt cataaaatgc
     4441 ctgactatca aagtgttcag ccatcatttc tgttaaactt gattttccgg caccaattgt
     4501 acctgctaaa acgatcacgc tcatttacct ccagctcact tcatcactaa atattgtgtt
     4561 taactccaac cttttttaaa tataccccca atatctagta gtgtcaattg tattttttct
     4621 agtcaaagaa gaaaaaaagt caaaaaattc ttaagaaaaa agtgtttttt ctttagaaaa
     4681 cgtattctta gttttacttc tgagatggtt ttagtaaaat aaaggaggaa tgttttttga
     4741 gacccttagt ggacaaaaaa attcgtgaag cagcgcaact cgttttgggc gctttatttt
     4801 ttgcttaaaa atcactttta cgtgagaagg agttagatta tggcaaacta tggccaagga
     4861 gaatcaagcg gaaagatcat attgatgggc gagcacgcgg ttgtttatgg agaaccagcg
     4921 attgcctttc ctttctatgc aacaaaagtc accgcattcc ttgaagagct ggatgcaatg
     4981 gacgatcaac tggtttcttc ctactattca ggaaatttag ccgaagctcc tcatgcatta
     5041 aaaaatatca aaaaattatt cattcactta aaaaaacagc atgacatcca aaaaaacttg
     5101 caactgacca ttgaaagcac gattcctgct gaacgtggaa tgggatcaag cgctgcagtc
     5161 gccacagcag tcactcgtgc tttttatgat tacttagcat ttcctttgtc tcgtgaaata
     5221 ctattagaaa atgtccagct ttcggaaaaa atcgcccacg gtaatcctag tggaatcgat
     5281 gcagccgcta ctagcagctt gcagccgatt tattttacaa aagggcatcc ttttgactac
     5341 ttttctttga acatcgatgc ttttttgatt gtcgctgata caggaatcaa aggacaaaca
     5401 agagaagccg tcaaagatgt cgctcacctc tttgaaaccc agcctcatga aactggacaa
     5461 atgatccaaa aattaggata cttgacgaag caagcaaaac aagcaatcat tgagaattca
     5521 ccagaaacgt tggcacagac aatggatgaa tcacagtcac ttctggaaaa gctgacaatc
     5581 agcaatgatt ttcttaatct attgatccaa acagcaaaag ataccggggc attgggtgcc
     5641 aaattaactg gcggtggacg cggtggctgt atgattgcat tagcacaaac aaaaacaaaa
     5701 gcccaagaaa tcagtcaagc acttgaagat gcgggtgctg ctgaaacttg gatacaagga
     5761 ttaggagtac atacctatgt ttaaaggcaa agcacgcgca tataccaaca ttgctctaat
     5821 caaatattgg ggtaagaaaa atgaagaact catccttcca atgaacaaca gcctttcgtt
     5881 aacattggat gcattttata cagagacaga agtcatcttt tctgatagct atatggtaga
     5941 tgaattttat ctagatggca ccttacaaga cgaaaaagca acaaaaaaag tcagtcagtt
     6001 tcttgacctt tttcgtaaag aagccggcct ctcactaaaa gcttcagtaa tcagtcagaa
     6061 tttcgttcct accgcagctg gattagcctc ctctgccagc gggctagctg ctttagcagg
     6121 agcttgcaat actgctctta agcttggatt agacgatctc tctctttcaa gatttgctcg
     6181 acgcgggtct ggttcagctt gccgaagtat tttcggtggt ttcgttgaat gggaaaaagg
     6241 ccatgacgac ttaagttctt acgctaagcc agtcccttcc gattctttcg aagacgattt
     6301 agcaatggtt ttcgttttga tcaacgacca gaaaaaagaa gtgtccagca gaaatgggat
     6361 gcgtcgaaca gtcgaaacat ccagttttta tcaaggctgg ttagattccg ttgaagggga
     6421 tctatatcaa ttgaaacaag caatcaaaac aaaagatttc caacttctcg gagaaacgat
     6481 ggaaagaaac ggactaaaaa tgcatggaac gactttagct gcccagcctc cattcactta
     6541 ctggtctcct gacagcttaa aagcgatgga tgcggtgcgg caattgagaa aaaaaggcat
     6601 tccatgctac tttacgatgg atgctggccc taatgtcaaa gttttagtgg aaaacagcca
     6661 tttatctgag gtacaagaaa catttaccaa attatttagc aaagaacaag taattactgc
     6721 ccatgctggt ccaggaattg cgattattga ataaagggag atttttatga ttgaagtatc
     6781 tgcaccaggc aaactctata ttgccggaga atatgcagtt gttgaaacag gacatccagc
     6841 agttatcgct gcagtcgatc aattcgtaac agtcactgta gaatccgcac gaaaagtcgg
     6901 aagtatccaa tctgcacaat atagtgggat gcctgtacgt tggacaagac gcaacggaga
     6961 attagtttta gatattcggg aaaatccttt tcattatatc cttgctgcta ttcgtttgac
     7021 tgaaaagtat gcacaagaaa aaaacattct tttatccttt tatgatctga aagtaacaag
     7081 tgagttagac agttcaaatg gccggaaata tggattgggt tctagcggtg ccgtgaccgt
     7141 tgcaacggtc aaagccttga atgtttttta cgcgttgaat ttatctcaat tggagatttt
     7201 caagattgca gcactagcca atttagcagt tcaagataat ggttcctgcg gcgacatcgc
     7261 tgctagctgt tatggtggct ggatcgcttt ctcaaccttc gaccatcctt ggctccaaga
     7321 acaagaaact cagcattcta tcagtgagtt acttgccctg gattggccag gtctatccat
     7381 tgagccattg attgctcctg aagatttacg tttattgatt ggttggacgg gtagccctgc
     7441 ctctacttct gatttggtcg atcaagttca ccgttcgaga gaagacaaaa tggtggctta
     7501 tcagcttttc ttaaaaaaca gtacagaatg tgtcaacgaa atgatcaaag ggtttaaaga
     7561 aaataatgta acgttgatcc aacagatgat tcgaaaaaac cgacaattac tgcatgattt
     7621 atctgcaatc actggggtcg tcatcgaaac gcctgctttg aacaaattgt gtaatttagc
     7681 tgaacagtat gaaggagccg caaaatcttc tggtgcaggt ggtggcgatt gcggaatcgt
     7741 aattgttgac cagaaatctg gcatccttcc tttaatgagt gcatgggaaa aagcagaaat
     7801 cactccactg ccgttacatg tctatagcga tcaaagaaag gaaaaccgat gaatcgaaaa
     7861 gacgaacatg tttcactagc taaagccttt catgataaac aaaaaaacga atttgacttc
     7921 gtacggatca tccataaccc tttgccgcaa atagcagttt ctgatgtcga tctaagtaca
     7981 caggcagttg ggtttacact aagcagccca ttttatatca atgcgatgac tggcggaagc
     8041 gaaaaaacaa aaaaaatcaa ccaagatctt gcaatcgtcg caagagaagc agatttgatg
     8101 attgccactg gttcagtcag cgctgccttg aaagaccctt ctttagccga tacttatacg
     8161 attatgcgac aagaatatcc tcacgggaaa atcattgcca acatcggtgc agggacttct
     8221 gtcgaaagag cccaagaagc tatccgattg tttcacgcag atgccttaca gattcatttg
     8281 aatgcacctc aagagttggt tatgcctgag ggagaccgtg attttaccaa ttggaaagta
     8341 cttattcaag agactcaaac agccattgac gtccccctca tcgtaaaaga agtcggtttt
     8401 ggcatgacaa gagaaacgct caatgatcta gctgctttag gagttcatac agttgatatc
     8461 agcggtcgaa gcggaacaag cttcacccag atcgaaaacg cccgtcgctc caagcgggaa
     8521 ctgagttatt tagctgactg ggggcaatcg acagtctctt cattgcttga agcaaatgaa
     8581 gcagacactt ctatggaaat cctagcctcc ggaggtatcc gcaatgccta tgacatattt
     8641 aaagcccttt gtctcggcgc aaatgcagtg ggtacttcag gaaccgtact gacgcatctg
     8701 atgaatcacg gcgtagaaga aactattata ctgatgaagc aatggcaaga agagcttcgt
     8761 ctgctttata ctatggtcgg cgcaacgaat accgcggccc tacaccaaca atcactgatc
     8821 ttttccggac cagtgaagga ttggtgcgaa gcaagaggga tcgacttagt gaagtatgga
     8881 agacgcacag aaaagagcgt gggacaaaag taaagaacac ttttatccca cgctctaaac
     8941 acgtataaac ggcggaagca aaagcaactc cttcggaaat aagctgaaat tcacaaaaat
     9001 ttgaaaagca attttcgtga attccttctt atttcttgga gttaaacgct tctgtcccag
     9061 cctctttttt cgaataaatg atgtttaatc agctgtcctt cggtattcgt tcaagccgct
     9121 gatttcacaa cctctccact aaacggtgta ctaaagctct tttaaggttg ttttccgata
     9181 taggcaagta tgcctccgtc cacatacaag acatggccgt taacgaaatc agatgcgcta
     9241 gaagccaaga agacagatgg tccagccaaa tcgattggct cgccccagcg tgctgctggc
     9301 gtacgtccaa cgataaattg atcgaatgga tgacgttcac cgttttcttg tgtttcgcgt
     9361 aatggagcag tttgcggtgt agcaatataa cctggtccaa ttccattaca ttggatattg
     9421 tattgaccgt attcagaagc gatgtttttc gtcagcattt ttaatccgcc ttttgccgca
     9481 gcataagcac tgaccgtttc gcgtcctaat tcactcatca tggagcagat attgatgatt
     9541 ttaccgccgc ctttttcgat catatcccga ataactgctt ttgaaacgat gaatggggca
     9601 tttaaatcca cgtcgattac ttggcggaag tctgccgcat ccatttcgat catcggtgtc
     9661 cgtttgatga tccctgcatt gttgactaga atatcaactg aacctacatc ttctttgatc
     9721 tgttgaacca tcgcttgaac cgcttcttca tcggtcacat cgcagacata accttttgca
     9781 tcgatgcctg cttctttata atgcgctata ccttcatcaa ctgattcttg attcaagtta
     9841 ttaaatacga tttttgctcc tgctgtagct aaagagcgtg caatctcaaa tccaatacca
     9901 tagacagcac cggtgactaa tgctactttt ccatctaaac gaaacatatc catactaaat
     9961 tccatcattt tctctccctt atgcttattt taattgatcc atttgcacca tatccatgtc
    10021 tgtataggtg atattttctc cgcacattgc ccagatgaat gagtaattgc ttgtacctac
    10081 acctgaatgg atcgaccagc ttggcgaaat aatggcttgt tcattgtcta cgactaaatg
    10141 ttttgtttca tctggtttgc ccatcatatg gaacacacgt gtatcttcat tggcataatc
    10201 aaaatagaca taagcttcca tacgacgttc atgtgtatga caaggcatcg tattccaagc
    10261 acttcctggt tctaaaatcg tataacccat ttataaatga cagctatcgc tgaagcttct
    10321 actgctgtaa atatccccgt caagatacca ccgataatga tgacaatcaa tagaaggcta
    10381 ggaatcgcct cttttattat ttttccagca tgagccatct gtcctttttc gacaacaggg
    10441 tatttattct ttttagcaac gatgaatgct actagcatga ttcctagcgc ccacaaa
//
LOCUS       DACDAF010000091        10495 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.094, whole genome shotgun sequence.
ACCESSION   DACDAF010000091 DACDAF010000000
VERSION     DACDAF010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10495)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10495)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10495
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.094"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            171..872
                     /locus_tag="IVZ69_002272"
     CDS             171..872
                     /locus_tag="IVZ69_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HAP8184310.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(1444..2460)
                     /gene="tsaD"
                     /locus_tag="IVZ69_002273"
     CDS             complement(1444..2460)
                     /gene="tsaD"
                     /locus_tag="IVZ69_002273"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HAP8184311.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIVAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(2457..2921)
                     /gene="rimI"
                     /locus_tag="IVZ69_002274"
     CDS             complement(2457..2921)
                     /gene="rimI"
                     /locus_tag="IVZ69_002274"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP8184312.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLVEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(2928..3470)
                     /gene="rimI"
                     /locus_tag="IVZ69_002275"
     CDS             complement(2928..3470)
                     /gene="rimI"
                     /locus_tag="IVZ69_002275"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HAP8184313.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTIEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(3454..4278)
                     /gene="tsaB"
                     /locus_tag="IVZ69_002276"
     CDS             complement(3454..4278)
                     /gene="tsaB"
                     /locus_tag="IVZ69_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HAP8184314.1"
                     /translation="MYHCTSFAFGIFILRIKKYATMEGENVIAERIKYMITLGIDTAN
                     QTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAIDQLFADLQISPKDIDRIAVSDGPGS
                     YTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAANCIGVDKIIVPMFDARRKNVYAGAY
                     RWKENRLEIVLEDVHISASDLFTQLQKLNEAIYFVGSDCHKFFYEIKEILPSAMINTV
                     PAWDIPSGVTVAQLGALAEPVAEKQAFLPRYLKRVEAEEKWLETHTPGDESYVEKI"
     gene            complement(4367..5347)
                     /locus_tag="IVZ69_002277"
     CDS             complement(4367..5347)
                     /locus_tag="IVZ69_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HAP8184315.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPTDGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(5371..6855)
                     /gene="galT"
                     /locus_tag="IVZ69_002278"
     CDS             complement(5371..6855)
                     /gene="galT"
                     /locus_tag="IVZ69_002278"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HAP8184316.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLADYPQVIAGVVKWPMSVIRLQSTEKKLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(6867..7856)
                     /gene="galE"
                     /locus_tag="IVZ69_002279"
     CDS             complement(6867..7856)
                     /gene="galE"
                     /locus_tag="IVZ69_002279"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HAP8184317.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREVLGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            8105..8272
                     /locus_tag="IVZ69_002280"
     CDS             8105..8272
                     /locus_tag="IVZ69_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HAP8184318.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(8334..10145)
                     /locus_tag="IVZ69_002281"
     CDS             complement(8334..10145)
                     /locus_tag="IVZ69_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HAP8184319.1"
                     /translation="MKIGIIGAGPRGLSIAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNDLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSREGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGSMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLEIPLTYQDESFAEASRAFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPVIRTKELAALIDAGIFHLFEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(10142..>10495)
                     /locus_tag="IVZ69_002282"
     CDS             complement(10142..>10495)
                     /locus_tag="IVZ69_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HAP8184320.1"
                     /translation="KRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIAPSNE
                     ARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKNEHQN
                     HAVLLKKFIEMEACK"
BASE COUNT         2986 a         2220 c         1843 g         3446 t
ORIGIN      
        1 tcattcgctt caaaacaaat tattcaatac cattgtatat tttttacata ataacaaatt
       61 atatttgtaa agtattaaaa cttgtttcta atgttggtat gttaaaactt tacaaattct
      121 ttaaaaaaag tgacaataaa tatagtgaac aataaggaga ggacttttta atgcgtgtta
      181 ataaaatcga ttttcacttt tcaaaactca gatatcaacc tgattttgaa catttctcgg
      241 atgaagagtt ccaacagatc aaggaacata ctgttcttcg ttcttataaa aaaggacaga
      301 tccttttcga cgatggtgat cccagacaac ggttgtatat cttgaccaaa ggactcgttc
      361 gtttagaacg ttatgatgaa agtgcaactt attactacta tgactatgtg aatacaaata
      421 acctttttcc tatgtcagga atgtttggag aagagaccta cacttataca gctcaagcga
      481 tgactgatat tgaaacattc taccttcctg tttcctacta tgaaaaatta gcacgaaaaa
      541 atcccgaaca gttgatctat atgatacaaa aaatttctaa agtagttgaa atacatgaat
      601 tgcgtatcca aatcggattg acctctagcg cctttgaccg ggtaaaacaa aatttattca
      661 ttttgaaaga agaattgggc gtaccaacaa aagatggtca tatcaccatt ccttatccga
      721 tcaccttaaa agaattagca gtgaatagcg gcacgacacg tgaaactgct ggacaagtaa
      781 tcaaacaact acgtgattcc ggactgttag attatgacaa aaagcgtttt actttctgta
      841 agacagctac tactccagct atgagagaat aacgcgaaca aaaataagca gtgaccctga
      901 tatttatcag ggtcactgct tattttcctc cctaaaactt ctgaaagatc cggcagtttt
      961 agatcactgg gcaagactca aagattttct atgtgtgttt cagttatgta atattcactg
     1021 tttgcaaaaa atactgatag attaactaga ggaagcgtct tgtcctcatc cgacctagat
     1081 tattcgatat tcctcgacaa taaacgatta atcagtgagg gcaatcagag gaacggataa
     1141 tgatgaataa gctgtaaaaa atagggcttt gacaaaagcg tgtcacagcc cttatttcga
     1201 ttaaacggtg tgtacctgtc aactcttcgg tcacaagtca taatgttcat aaacatgagg
     1261 agctgttttt tgaaattgtt ccttgtgaat cagagttaaa cgacaggctt acgaactctt
     1321 gattaaacgg cgttcaaaag cttgcatacg cggtaataag aacagccagg tcaaaaacat
     1381 gagaagccgt ttttcctggg ctgttcttat tacttgatgc agggcagatt tttcacaacc
     1441 tctttattca gataaaacca agcttggatc agcattcaac tgatagctag caaaatttct
     1501 tttttgcatt tccacatgtg ctgctgctcc aatcattgca gcattatctc cacaaagtcg
     1561 aagaggggga atcactagtt ctacctcagg gagtttagtt gccaaagcat cctgcaatcc
     1621 ttcacgcaac ccttgattgg ccgctacacc tccagctaca atcagttgct tgactggata
     1681 attttgacaa gctcgaagtg ttttagtaat caatacatcg atcacacttg cttgaaagct
     1741 agctgctaaa tcatttttgt ctagatcttc tccacgctgt tgtgcattat gcaccaaatt
     1801 gataaatgca ctttttaatc cgctaaaact gaaatcataa ttatcttcat ggatcatcgc
     1861 tcgtggaaaa tggtaattat cttttccctg atgagctagc tgatcgattt cttttccgct
     1921 tgggtaagaa agacctaata ctcttccaac tttgtcataa gcttctcctg ctgcgtcatc
     1981 tcttgtctcc ccaatgattt catatgatcc atcttcttgc atatagacta attctgtatg
     2041 tcctccgcta acaagaagtg ccatcaatgg aaactggaat ggtttaacca gacgggctgc
     2101 atagatatgc cctgccatat ggtttacagg aataagcggc aattggtgtg cccaagcaaa
     2161 agccttagct gcagaaatac caatcagcaa cgagccgaca agtcctggtc cataagtgac
     2221 agcgactgcc gataaatctt ctgccgacac accagcttct accagtgcat cttccaagca
     2281 taaggtgatt tgttctacgt gatggcggct agctacttca ggaactacgc caccaaaacg
     2341 tttatgactg tttatttgag aagcaacgat gttagataag atctctgttc catttctaac
     2401 gaccgctaca ctcgtttcat cacaacttga ttcaatcgcc agaatcaatt cttcattcat
     2461 ttcatcgtct ccgtttttaa ctttctgctc ataatgatcg catcttccgt cggattgcga
     2521 taatatgatt tccgtttacc taatatacga aacttttctg attcataaag ttttcttgct
     2581 gcttcattag atagacgtac ttctaaaaaa acatgcagcg aatcttttat ttgttccgta
     2641 atcagtaatt gtaacaaatg ccgtgcatgc ccttttcctt gttctgaaac tgcaacagca
     2701 atatttgtga tctcgacttc atctattact ttcgagtatc caataaagcc acagatctgg
     2761 ttatcttcaa ctaaaagcag ataatcagag tgaggctgtt ggatgtctgc caaaaactgc
     2821 attttcgtcc aaggtgaacc atgtggataa gcattttcgc taatcatcca tacgcattct
     2881 gccaagtacg cttcatcaaa atcttttttt ctgcaaatca actaatctca ctcattttct
     2941 aaaagtttta tcatatccaa cgcatcttct tttgtttcag tgtaatatct ttttttgatc
     3001 gttgttgctt gaaaacctaa cttccgataa agtctttgtg catcttgatt actcatacgc
     3061 acttctaatg acatcgtctc acagcgattc attatagcaa agttctcgat ttcgtcaata
     3121 agcagcgaac cgattcgttt acgctgatat gccggtcgaa cggcaatatt cgtgatatgg
     3181 caatctaaac cgaacgctct tgaaccgata aaaccaatca ttcttccatt atcaaagata
     3241 cctagatata gatgaggaag cggtgacttc aattctgata taaaggcact ttttgtccat
     3301 ggcaattcgc cattatagac ttctcgttcg acatccagca gctctttgat atcttctgta
     3361 gtcaattctc ttagtacgta acgacgatcg atttgttcga ttgttttttc tgtataaatc
     3421 attttatctt gaaaaaagct tctggcatac gctctaaatt ttttcaacat aactttcgtc
     3481 tccaggtgtg tgcgtctcca accatttttc ttctgcttct acccgtttta aatagcgagg
     3541 aagaaaagct tgtttctctg caactggttc agctaaagca cctaattgag ccacagttac
     3601 accacttgga atatcccatg ctggaactgt attaatcatc gcactaggca atatttcctt
     3661 tatttcatag aagaatttgt gacaatcact cccgacgaaa taaatagctt cattcagctt
     3721 ttgtagttgt gtgaacaaat cagaagcaga aatatgtaca tcttcaagta caatttctaa
     3781 tctattttct ttccagcggt atgccccagc gtatacattt tttcttcgag catcaaacat
     3841 gggcacaata attttatcca caccgatgca attagccgcg atggttttca gactagatac
     3901 tcctactagc tctttatcta atgtataagc aatcgttttt gctgtcgtta cacctatacg
     3961 aagccctgta taagaaccgg gaccatcaga aaccgcgatt cggtcaatgt cttttggact
     4021 tatttgaaga tctgcaaaca attggtcgat tgcaggcatc agtgttacac tgtggttgcg
     4081 tttgatattt gtttgtattt gtccaagaat ttgttcgtct tctaccacac cgatcgccaa
     4141 agtttggttt gcagtatcta ttcctaatgt aatcatatat ttgatccttt ctgctatgac
     4201 attctcgcct tccattgtag catacttttt tattctgagg atgaaaatac caaaggcaaa
     4261 actagtacaa tgatacatga ttatctgctg gcgggcaaat tttgcccctt cctgaaacac
     4321 aaaaaagctg cggtatcact tcatttcccc acagcttttc catcttttat ttcgttgatt
     4381 ctcgaataat caactctgtt tccacaataa tctttcttga aaccggtgct ttggaattac
     4441 ttaattgaag aatcgtctcc actgctagct ctcccatcca ttcggtataa acttttacag
     4501 tagaaagaga gggcgttaca tatttcgcta cactgacatc attgaaaccc atcacagaaa
     4561 tatcttctgg taccactaaa cctttttctt gaatcgcttt cagtgcgcca atcgctaatg
     4621 catcattagc tgcaaaaagc gcatcaggaa catgcggatt cgtttttaaa tactgcttca
     4681 ctgcttgata tcctgactcg acagaaaaat ctgcttcgat aattggacct tcgtcgtagc
     4741 ctttttctgc caaaacttgt tgaaatgcca taattctggg atcttttagc cgctgatggt
     4801 ttttcttcgt atattctgtt ccagcaagca tagcgatatg ttgcgcttta tgggagacaa
     4861 aatgttcaat gactttttga acacttgact taaagtcgac aactagagag tcgattcctt
     4921 gagaagtgcc gtcagaatct accaaaagca aggcattttg ggatcctttc atttctaata
     4981 actgagcttc gtcgaatttt cctagtgcga tcgttccatc tgtcggaaga tcactaatgg
     5041 aatcccacgt ttctttcaat aaagtaacgt ttgcttcttc tgcctttttt tcgattccta
     5101 gacgaataga taaataataa agatcttcaa gctcttccgt atcgtcgtac cactggatca
     5161 ggcgaagcgt ttgcttagta tttgctgcat ttttacgatg tttcgtataa tttaagcgtt
     5221 ctgctgcttc aaaaattttt tgctttgtgg ctaagccaac ggaaagatca ggatcatagt
     5281 tgagaactct tgaaacagta gcaggagaaa ctcctgccaa ctgcgcaatg tctttaattg
     5341 ttgccatttg tctctcctcc ttttttacgt ttataaaatt gcagtaaatc gttcaaacgc
     5401 tgcctgtcct ttttcatctc gcttgaatac tccagcgtct tccagtacac gtgcaaaaac
     5461 ctgacctaca gatttttgta cgacatcggt gaccgtatct ttcgtcaaat caggatgttc
     5521 tttttttaat tgttctgccc acggacgatg atattcagcc atctggtttt cttctcctaa
     5581 taagaaatgc tctacttcta ctagttctgg tttcaaacga ggtggtaaaa cagcaagccc
     5641 cattacttcg atcaacccaa tgttctcctt tttgatatgt tggacatctt tatgtggatg
     5701 aaaaatccca tcaggatgtt cttctgaaac attgttgtct cgaaggacaa ggtccaactc
     5761 aaagtaattg tcccttcttc gtgcaattgg cgtaatcgta tggtgtggtg taccatctgc
     5821 tgaaaaagct ctgatagata ctgtttcatc cgaatatgct ttccactttt ccaatactga
     5881 gttagctgct tcaatcaaca attttttctc tgttgattgc aaacggatca cagacatcgg
     5941 ccatttcacg actcctgcga tgacttgcgg ataatctgct agtttgataa gtttttctat
     6001 cggtgctttt gccataggaa attcatgacg tcctgcctga taatgatcat gagaaagaat
     6061 cgatcctcca acaatcggca agtcagcatt cgaaccaaca aagtaatgag gcaagacttc
     6121 agtaatccga agcagtctag caaatgtttc ctttgtgatt ttcatcgggc ggtgttgttc
     6181 tgataaaatg atcgaatgtt cattgtaata agcataagga gaatattgga atccccagct
     6241 ttcaccgtct agattcattc gaataatccg gtgattggtg cgggctggat agttcaagcg
     6301 acctctatat ccttcgtttt ccatgcaaag catgcaggta ggatagtcta cttttaccgc
     6361 ctcgcgttct gctgcgattt gttttggatc tttttctggc ttagataaat tgattgtgat
     6421 ttccagttca ccatactccg actctgccgg aaatttgatg ttttttgcga tggctcttgt
     6481 tttgatgtag tcatttttct tacttaaatt aaagaaatac tcagttgctt cctctgggct
     6541 tttcgaatag tgctgtgcaa agaatgcatt gacgactgaa ggtggcggtg tgagaaaatc
     6601 cattaattgc gcttcaaaaa tctcttgttc tgctggcaat tctgaaagaa caccattttc
     6661 tcttgcctta gcgacaagct gatccaataa gtctacagat tcttccttaa ctggtcttac
     6721 ttcaatgctt tctagagcat cttctcctac catccctaaa agacgattct gtaaatataa
     6781 gcggtccatt tccatccatc cgccagcttc gatcgcaagt gtggcaaaat cacaaatcgt
     6841 ttgactgatt gacatatctc attcccctat tcttcataac catttggatg gctgacatgc
     6901 caatcccatg ctgttttgat aattgctttg atatctgtgt attcaggttt ccaacccaga
     6961 acctctctcg ctttttcact tgaagcgact aatcggctag gatctccagc tcttcttggt
     7021 gctatttctg ctggaatttc ttttcctgtc acttctctag ctgcttctag catttccttg
     7081 actgagtatc ctttgctgct gcctaaattg aagaagttgc tttcatttcc ttctttcaag
     7141 tattccaaag ctaaaatatg tgcagcaatc aaatcttcta cttgaacata atctctgata
     7201 catgttccat ctggtgtatc ataatcgtct ccataaacag ccaatgcttt tctttgacca
     7261 agagctactt gtaaaatgat tgggacaaga tgcgtttctg gtgtatgatc ttctccgata
     7321 gatgcatctg cttttgctcc ggctacattg aagtagcgca aagcgacata gcgcatgcca
     7381 tatgcttggt cacaccactt catcattttt tccatcatca atttactttc accatacgga
     7441 tttttaggat tagctggtgt atcttctgtg attggagact cttttggttc tccgtaagtt
     7501 gctgcagtag aagagaacac gattttattc acattgaact cgtgcatgac ttcaagtaag
     7561 atttgcatac cgtatacgtt gttgttgaaa tacatcaatg gtttttcgac agattctcct
     7621 actaaagagc ttgcagcaaa atggattact ccttcaatcg gttccttttc aaatacggaa
     7681 cgtagaaatt ctttatcccg gatgtctcct tcataaaaat gagcatctgg atgtactgct
     7741 tgtttgtgac ctgtgagcaa attatctacc acagctactt gatacccctt ttgaactagc
     7801 tggtctacag cgtgcgaacc gatataaccg gctccgccta gtactaaaat tgtcataaaa
     7861 aacactcctt tgattagtaa aattgtgttt gttgattata tataatttaa aaaaacgaag
     7921 tttactttta tggtgaaaac aaacaaagta aaatttcgta aattcatatg gtaaatttat
     7981 aataaaacat ttagtaaaca ttttcaagga ttttttgcaa aggtttacaa acaaacgtaa
     8041 aactagcctt tttttctctt ttgttccata atagatataa caaataataa atgaggtgga
     8101 ttcaatgaaa aaatttgtat ctggaatatt agtaggaagt ctggcaacag ccgctgccgt
     8161 tgctggtttg gtcgcttctg tgaaaaaaac agtgatcgat ccaattgacg aaaaagaagc
     8221 aatgatcgaa gaaaaccgta aaaaagcaat gcgcaaacgc gtttctcgtt aataattatt
     8281 taaaaacacg catgaagact tgtgaaagaa cagataagtc atcatgcgta tttttatttg
     8341 tcagtcaata taagttgtgc tattttatct gcctgtctca gattccatgg atctgtataa
     8401 ggtctagcta ctgctgcagt tagccaatcc acaccttcaa caggtattcc atagcaataa
     8461 aagtcagact ggatttcccc tgaagcatca atcacgcgat tcgtacctcg ctcaacatct
     8521 atagcttctg aatgataact tcctgtatta tctgaaaatg aaaaagggcg aacaagtttg
     8581 ttttccttca aattttttat gacaggatta cttgaacgag aaaagcttgt ttgtggcaat
     8641 cgagcttcaa tcaaatagcg actgctgatt tctttatctt gtagagaaat aacatagcgg
     8701 ttgtgctttt gctgaatatc aaatggcggt tcgaacaaat gaaaaatacc cgcatctatc
     8761 agtgctgcta attctttcgt ccgaatgact ggcggaccga tcgttaaaaa gctatttaga
     8821 tgagtaaacc atccccatag tatttctttg tattcctttg cagaaaaaac gtgccattca
     8881 atagcctgcc ggattggatc acgccagtct tttaatgcat caaatgttga agcaaatgct
     8941 cctgtgcaat tgcctttttc cgcttctttt atctgccctt caataaatgc tcggctagct
     9001 tctgcaaagg actcatcctg ataggtaaga ggaatttcta aatacgacca atcccatcta
     9061 taagggatta gtgctggatg ctttccgaga cactcctctg aagagaggga gagaaaatca
     9121 tgctcaaaat ttttctttgg aatcggcaaa tgatattctt cgatgatttt cttgtaataa
     9181 aacaactcaa cgtctttttt cagatagtca aaaaatgttt cgccagtcaa aaatcccgac
     9241 tgatgccatt gctccaggtt ttcttttgtt agtaaccgtg gccatgccat tgatccgcct
     9301 tgcttttggt ttcttcctcg agggtaataa gggagccccc ttcttgatcc actgtataca
     9361 atcggttcct tgcctgatgg atgatagaca agttttcctt tttcgttctc gaagcgccct
     9421 tctcttgata ctgtaaacaa tccgacataa tcaaaaaaac ttaagcctag acctcttaaa
     9481 aagacatttt ctttaggcgg tatcttcgaa agatcgacat ctgcaggatt agaaggaagc
     9541 tgatacagta aatcattttt ctttgcgtag tctacccaca ctctttcttc ttctgtctca
     9601 tcattttccc agtgaccgct tgctaaaaca agctgatcga tagaatagct ttgctgatct
     9661 gtctgtaaaa gataaccatc ttttcttttg ctgacttttt ttactaaaga ataaacaaac
     9721 tgaatagaag ctggaaattc ttcttgcaac tttgagaaaa accagcgttg atagagtccg
     9781 tataaacatc gagtagattg ctgatctttt tccagacgat tgatttcttc tataattagt
     9841 tgcttatttt tggttaccgt ctgttcgata taatctgtag caggtccttt actccattga
     9901 aacaagttgg gtccctgtgt taccaatcct ccactggaca atgtttcatc tgtaaaaagc
     9961 gtcacttgtt gagaaacaga attcattaat aactccggtg gctgattcaa ccgccaaact
    10021 cgacctccag gaccattggg atcgaaaaga aaaagttcaa gagaatgtct gtcctgatta
    10081 ttatggagaa tcctttctgc tatacttaat cctctaggtc cggcaccaat gatccctatt
    10141 ttcatttgca tgcctccatt tcgataaatt ttttcaataa aacagcatgg ttctgatgtt
    10201 cattttttgc accataaaca aaagtaatga ctggatgttc tttcataagt tgactgagtt
    10261 taaaaatagc ttgcttcttt tcttcttcga aaatcaattc ttgctggtat ttctttgcaa
    10321 atgaagcaaa tcgttctggt acatggtcaa aagttttgcg tgcttcatta ctaggtgcaa
    10381 tttctttcaa ccacagatct aactgcgctt tttcttttga aattcctcgt ggccagaacc
    10441 tatccacgag tattctatag ccatcctctt tttcagcatc aaggtaaaca cgttt
//
LOCUS       DACDAF010000092        10320 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.095, whole genome shotgun sequence.
ACCESSION   DACDAF010000092 DACDAF010000000
VERSION     DACDAF010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.095"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(12..85)
                     /locus_tag="IVZ69_002283"
     tRNA            complement(12..85)
                     /locus_tag="IVZ69_002283"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(49..51),aa:Ile,seq:cat)
     gene            complement(274..1293)
                     /locus_tag="IVZ69_002284"
     CDS             complement(274..1293)
                     /locus_tag="IVZ69_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP8184321.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RSDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1304..1510)
                     /locus_tag="IVZ69_002285"
     CDS             complement(1304..1510)
                     /locus_tag="IVZ69_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP8184322.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
     gene            complement(1643..2602)
                     /locus_tag="IVZ69_002286"
     CDS             complement(1643..2602)
                     /locus_tag="IVZ69_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP8184323.1"
                     /translation="MTYTHLTTDELVIIESYFKMNQSVAKTAHCLNRSRQTIHKVYLF
                     FKQGKSALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPIS
                     CSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEF
                     GHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFK
                     SITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNS
                     VDEFFIQSVASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
     gene            2768..3202
                     /locus_tag="IVZ69_002287"
     CDS             2768..3202
                     /locus_tag="IVZ69_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8184324.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(3280..3813)
                     /locus_tag="IVZ69_002288"
     CDS             complement(3280..3813)
                     /locus_tag="IVZ69_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HAP8184325.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(3907..5085)
                     /gene="mutY"
                     /locus_tag="IVZ69_002289"
     CDS             complement(3907..5085)
                     /gene="mutY"
                     /locus_tag="IVZ69_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HAP8184326.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(5078..5875)
                     /gene="recX"
                     /locus_tag="IVZ69_002290"
     CDS             complement(5078..5875)
                     /gene="recX"
                     /locus_tag="IVZ69_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HAP8184327.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            5982..7364
                     /gene="rlmD"
                     /locus_tag="IVZ69_002291"
     CDS             5982..7364
                     /gene="rlmD"
                     /locus_tag="IVZ69_002291"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HAP8184328.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(7538..8116)
                     /locus_tag="IVZ69_002292"
     CDS             complement(7538..8116)
                     /locus_tag="IVZ69_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin-binding protein"
                     /protein_id="HAP8184329.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            8438..8908
                     /locus_tag="IVZ69_002293"
     CDS             8438..8908
                     /locus_tag="IVZ69_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HAP8184330.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(9016..10242)
                     /locus_tag="IVZ69_002294"
     CDS             complement(9016..10242)
                     /locus_tag="IVZ69_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LytR family transcriptional regulator"
                     /protein_id="HAP8184331.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         2987 a         2057 c         1792 g         3484 t
ORIGIN      
        1 ggctacgtta atgtaccctg taggactcga acctacgacc ggacggttat gagccgtctg
       61 ctctgaccaa ctgagctaag ggtactggtt gttgccacat aaagccataa acaatcaacc
      121 agtagaatgt gtggcaacaa acctgttatc gcatagcttg gagtgtgact attatgggtg
      181 atagtgaaga tatgcgataa catcactatt ttatcgaatg atttttatag ttgtcaatat
      241 agttatgtaa tgctcctcaa cgaggagcta tttttatcgt ttaggaatat ttaaatacca
      301 acgtttgtca tggaaatctt gcgcaccgcc tttagtgttt ccctctggat cattcgttgc
      361 ccgcatcatg acatagactt tcttattagg gaagttacgc atgttaaaag atacatgata
      421 gccaacattt ccagaagtat tataagcttg atttacatct gatctataaa ttccatcagc
      481 tcttactcga gctaattctt tcccagtatt gtaatccata atgaagatat actcgtattt
      541 atagttagca atgtgccatc cagctacatg caaatttgca ttttcgattt ctccaaactg
      601 atcaatgtgg gcgtaattcg ttccatctgt cagtgtagga ttagctgcac cagctcgtgt
      661 tggatcaatg acaggcttgt tttcagaagt tgttggattt tcatcggtaa atccatgagc
      721 taaatcatat gctaattttt ctttacttac gcccatttca gaaagataac cgtaaggatc
      781 tgtatgatcg ccccagatgt tttgtgttac ccataaatgc gatttgattc ccggttggtt
      841 ataaggagtg tccaacgtta atggaatacc atatttcatt gctgaatctc tagccaattc
      901 aacgtatgcc ttgtagtttt tctcaaacgt tgctttatca tgtgtgtgtt gtaactcaat
      961 ctgcacagga ctgttggcat tagcatacga accagcaccg tactgtacat aaccaggttg
     1021 accgacttga taaacaattc cgccgtctcc cacaatataa gcagtataag cgctagtcca
     1081 tgaacgttgc atatactgcg cttcattgcg tcctgttgct gtttcattag ccgtttcatg
     1141 cagtaaaata tactgattat ttgctacttg tgagctacct tcatttgcgc ccaaattaaa
     1201 ttcattgttg atagtatagg caaatccgtt aattggcaat aaaaaaagag ccgttaacag
     1261 gctcatcgca gtaatagtaa ttttcttttt catatctatc ctcctattta tctgatgaaa
     1321 ttttcttata cgttcgattt gatacaccta aaatactccc tagaaatgct ccaaaacctg
     1381 taataatcat caccgttata tctgtgtacc gccagttaac accttttccg acaagaccga
     1441 caaaagtcgc taaagcgggg ataactacta tagcgatcca tttcaaaata tcaaaggttc
     1501 tattgttcat actatccacc tcccttcatt ggttgggcta ctttcttttt caatcgcttg
     1561 ttttcttcta tcaatatttc tctttctgaa agcaaggcat caatttgccc gtccagttgt
     1621 tcaattttat ctttcttaat tgtcaaatta agttagacag atcatcaata cttacgtaac
     1681 tcaaaaatac ttccaaaggt gttcgataat ccagtgattt tctaggaata ttatttcgtt
     1741 tagatgcgac agattgaata aaaaattcat ctactgaatt gaaatccata gatttcaata
     1801 aaccatctct acgtaacaat ccgttagaat tctcgtttag gcctctttga gacggcgttc
     1861 ctggatcagc gaaataaatg gcaatatcat tgacattact gatctgtttc caatttgaaa
     1921 attcctttcc acaatcaaaa gtgatggatt tgaataggtt tttcggtaca gattcaaacc
     1981 attgatttaa ttttttttca atatcaatcg cttgtctacc acacggtttc aatgtgatga
     2041 taacttttga taatcgttca actaaggtaa ttacagcact tttatgtttc agacctacga
     2101 tagtgtcacc ttcaaggtga ccaaactcat ttgagaattg gctataatcc ttttcacgtt
     2161 catgaataga gcggcggaaa gtttgttttc cacgtctttc ttgatgtcca ttcggtttac
     2221 gcttgccttt catcggtaag tcagaagaat caaatagccc ctttttgaac atacgataaa
     2281 tggtacgagc agaacaacta ataggaaacg ctgcacgacc aacaatcaca tcgggtgtcc
     2341 atccttgaac aacctttctt tgaatatatt ctgattgttc ctcgggtaaa acaagcggac
     2401 gtctaccaca gtttgatttg tttttcttat actgttgata atattctaag gctgattttc
     2461 cttgcttgaa gaacagatat actttatgga tcgtttgtct tgaacgattc aagcaatggg
     2521 cagttttagc aacagattga ttcattttga aataagactc tattattaca agttcatccg
     2581 ttgtaagatg ggtataggtc atttgtactc actccttata attctttggt cggaactatt
     2641 ttgagtgtag cacaaatgac ttttttagtt gtctagctta attttacaat cggcgttttg
     2701 aaaacttgcc atacttttta tttgttttat tttccagtat actatacgaa aggaaggtgg
     2761 ctagaccatg aaagttgtac aaacaaaaga tacaatgagc aatatttact tagatgctgt
     2821 acggatcagg catcaagttt ttgtagtcga acagggtgtg cctttgtctc gagaaataga
     2881 caaagatgaa gcccattgta tccacttcgt cctgtactca gataaaaaag aaccgcaagg
     2941 aactgtacgt cttttgcctt tagaaaacgg aaaaatgaaa ttacagcgga tggcgattct
     3001 ttctgaatac agacaccaag ggttaggaaa aatattgatt gaagaagcag aaaactttgc
     3061 taagaatcaa ggctataata cgattttatt aggggcacag tccacagctg aaacttttta
     3121 cgaaaaacta ggatatacag cttacggcga tccttttgaa gatgctggca tgcctcatat
     3181 ttatatgaaa aagactttat aaaaatttat ttcgaaaaaa gcaaaaaaca gcaagctttt
     3241 gagaaaaatc tctcactggc ttactgttct tttttgtgtt tacttacgcg acaattgctt
     3301 gtaacggtta taccaaatat caatatagcc ttccgagaac gggccatctc cattattgat
     3361 ccagtcaacc agaatcttca cattttcttt taggatgaag tcaatatcgt tcgggtaatt
     3421 catcattttg ctgtgcatct catattcatc gacatccaat agtcgtttct cgccgtcagg
     3481 aaataccttg atatccaagt catagtcgat atatttcaag gcctcatcgt ccagcaaaaa
     3541 aggtgaagct agattacaat aataggaaac ccccttttct ctgatcattg ctattacatt
     3601 gaaccagtat tttttatgaa aataaacaat cgctggttcg cgcgttaccc atcggcgtcc
     3661 atcagattca gtgactaatg tgtgatcatt cacgccgatc atagagtgtt cgcttgtttt
     3721 taataccatg gtatctcgcc acgttcgatg caatttgccg tcgtgcttgt aactttggat
     3781 cgtcacaaac tctccttctt ttggaactcc catagcaacc cttccttaag cagcattttg
     3841 tgctttgtgt ttgggtgttc attacaccga catcataatt attatatcaa taaaaatgag
     3901 ctttgcctag aaaggattcc tattgtttcg atttttctct aactgatcta ccagtttcat
     3961 ttggacctta ggaaaaacga ccgaatcaaa tgcatcaggc ttcaaccact tcgaagtttt
     4021 gttctcggta aattcttgtt ctgctccctc ggttgcccgt ccgtaaaaaa ggagaacatg
     4081 ccatttcaga tgactaaaaa tatgagtaac ttctcctaaa tgtcgtgtct gccaaacaaa
     4141 gagttcctgc ttttcaaatg ggagattttg ctcttcttct gctactaggt catcaaacag
     4201 atcgatttct ggctttgttt cccattcttt tttcaatcgc tcatactcct cttgtgtcac
     4261 ttccatcatt ggaaatgtcc acatattcgc cagcaatttt tggctatctc tttcttcaaa
     4321 ataatacgct ccagaatgat tttgaagagc tgcactgata taataaacgt cttttggctt
     4381 tgcttttttt gtttttacag gaaaactcgt ttggattcct cgtttgttag ctaaacaaaa
     4441 ggcttggatc ggacaagtct cacactttgg agaagttggt gtacagatag ctgaacctag
     4501 atccatcatt gcttggttga attcacctgg atgcttttca tcaatgattt tccgcatcgc
     4561 ttcatcaaag attttcctgc tagaagcttt tgcgatgtct gcttcaatgc aaaacaatct
     4621 gctgactact cgcatcacgt tgccgtcaac tgcaggttct ggaagtccaa atgcgatact
     4681 tgcaatcgcg cctgtcgtat atggtcctat tcccttcaat gagctaattt cttcaggcgt
     4741 ttgcggcatt tccccatcaa attctgacat gatctgttta gcagcagctt ggatgttccg
     4801 ggctcttgag taataaccaa ggccctccca tgcttttaaa agcttttctt ctggagcatt
     4861 tgctagctct tcaattgtag gaaaccattc catgaaacga taaaaataat cgatcactgt
     4921 gtctactctg gtttgctgaa gcatgatctc agagatccag atacgataag gatcacgatt
     4981 atagcgccaa ggcaggtttc ttttttcttg ttcataccat tgaatgaact gatcttgaaa
     5041 ttcttttgtt tctttatctg tccatttttc ccattcttta ttcactttcc tcttcctttt
     5101 ccgtaatgaa tcgctggatc atatccaaat caaatccttt ttgatataag ctttgcttta
     5161 cttttagatt tcttttttta ggttcaaacc ttaaatttct tcgccatagt ttatctcctt
     5221 gtttgactaa ataatcatat tctatttctt gatctgcttc ttgcggaaga tcagctatcg
     5281 cttgttggat cacttcttga gaaaagcctt tcgtcatcaa tgtttgttgg atttttctca
     5341 ataattcttt ttggcttttt ccgtgatttt ttccaaacgc tttttcggct gtctgatgtg
     5401 cattttgaac ttggtcttca aatgtatatt ggctgagcgc ttgttcaatg atttcaggtt
     5461 tcaaaccttt ttgctgcatc tgctgcgcta atttctttgg tcctttgtca cttaagcgca
     5521 tattcgtgcg cacataactt tccccataga ccaaatcatc gacaaggtcc aattctttta
     5581 agcgggctac gattttattt cgatcttctt gaaggatttc cttttctttt aagtatgttc
     5641 ggatttcttt ttccgatcgc aactgataac ttaagtaatt cattgctagg tgaaaaccga
     5701 aatcagctcc gctactcttc ttgatctctt ggatagtttc ttcgtctaat tcccgtcctt
     5761 ttaataatcg atagcgtact aatacatctt cagatacttg taaagcttct ccttcagata
     5821 aatctacgcg atagaaaggg cctttgcctt tactgattct cgtaacggtt aacataaaca
     5881 tcctcctcga acatatattc tctatcatac cacagaaaat ccccgtaatc aggtattata
     5941 tgttagaata aaccacagaa aaaagaaaaa gggagatact tatggcagaa acaattgtca
     6001 aaactggaca aacggttcct ttgaaaatca agcgtttagg cataaatggt gaaggaatcg
     6061 gttatttcaa acggttgatc atatttgttc catatgcact accaaaagaa gaagtactag
     6121 tgaaaatcac gaaagcaact cctcgctatg cagaaggaga attaataaaa gtcaaaaaaa
     6181 caagcaaaga tcgcgtagtg gcaccatgtc ctgtttacta tgaatgcggt ggctgtcaat
     6241 tacaacactt agcttatcaa gctcaattgg attttaaaaa ggatctgctt ttgcaagcat
     6301 tggaaaaatt caaaccagca ggctttcgat cttatcaact tttgccgacg atcgggatgg
     6361 atgagccttg gcattataga aacaaagcac aatttcagtt acgaaaaaat aagcagactc
     6421 aaaaaattga agctggttta tacgaagcaa actctcatca gttagtccct ataacagact
     6481 gcttggttca agaacctcga acacaaaaag taatgaatac tgttgttcaa ctattgaata
     6541 aatttgatgc acccatctat gatgaacgga caaacagtgg aatcttccgc acaatcatgg
     6601 ttagaatcgg tgttaaaact ggggagttac aagttgtttt tattactcgc agtaaaaaat
     6661 tcccgcaaaa aaacgcaatg atccgtgaga tcaatgaacg actgcccgaa gttgtttcaa
     6721 tcatgcaaaa tgtccaggca caaaaaacgt ctctcgtgat gggggatgaa acgatccact
     6781 tatggggaaa agaagccatt gaagaacaaa tcaatgaagt gactttcgat ctttctcctc
     6841 gtgccttctt tcaactcaat cctcagcaga ccgaattgct ttatggcgaa ggaatcaaag
     6901 cattagatgt ccagcctaat gaaacgatcg tggatgctta ttgcggagtt gggacgatcg
     6961 gcttaagtgt agcaaaacaa gccaaagaag tacggggaat ggataccgtt cctcaagcaa
     7021 tcgctgatgc aaaaaaaaat gcggaaagat taggatatca caacactcga tatgaagtcg
     7081 ggacagcaga gcaagttctg cctaaatggt tgaatgaagg ttttcagcct gatggtatca
     7141 tcgtagatcc accacgtacg ggtttggata acgcattgat ccaatcatta ttgaaatacc
     7201 ctccaaaaaa acttgtttat atctcctgta atgtttctac acttgccaga gatctggtta
     7261 atttaagtaa aaagttcaag attgaatatt tacagtccgt cgacatgttt cctcagactg
     7321 cacgttgtga agttgtcgtg aagatgacga gactcgctga ctaaatgaaa gaggttgtga
     7381 aaaagtctgc cctgtatcaa gtaataagaa cagccaaaca aaaatagctc ttcatgtttt
     7441 atgaatactg tacttgtgac cgaagagtta acaggaggac actatttatt taaaaaaagg
     7501 gttgtgacat agtttttgtc acagcccttt ttgattatta ttggatattc acgtctatca
     7561 cttgataaaa tgcatttgtc gtatcgctga tattccatac tgctaaaatc acattatatc
     7621 cttttcgatc ctgcggaagt gtgatcgttt ggttgactgt ttttggtgga acagttgctt
     7681 tgtcgtctat ttttgtgatc aattcaaaat cactaaattt caaaggttga ttaggattcc
     7741 aagttggttt ggtaatgtag taatcccaag tacttgtccg atgttgtgct gttaaattcc
     7801 aagtaatatt taatgttcct ggattaacca tgtttttatg ccatctgtta gatgtctgtt
     7861 catctaaagg ctcaaagccg ctgactcctg cactagcaat ttttccatca atgaatgtat
     7921 ttttggtagc ttcgatactt tgcggttccc attgtgctct tccgacattt tgatttaagt
     7981 ttcctgctgc tgatgttcct aggtatgcac ggcttcctgg agaagtaata taaccatgcg
     8041 caaaacctgg aatgctaaaa ccgaacaacc ctaaactaac taacccaata aacaataacg
     8101 tactaatctt tttcatgtag aaacctcctt catttgataa ccacattgta aacgctttat
     8161 tgtattaaca caaacattat gcttttataa ttttatgttg aagtaaaaaa ggtgaaaaaa
     8221 gtaagatgca gattataaca gaagtagacg agaaaagtac aaatagaaaa catgagaatc
     8281 aaatcatatg atctttttca aaaacatcat tcatataaac aaatgttcaa ctttttaata
     8341 acaacaatta tcaatttttt tcttacttca caaactaaat acaggtcttg ctgtgagcct
     8401 tcatggtaaa ctaatattat agaaaggagt tagtaaaatg aagatgataa aagatattcg
     8461 tttttgggtt tgtgttatag gaattgtcat attaggcttt ttatcagggt tgcttagcgg
     8521 aaatcccgga aaatattact attctttgca acttccacca tttgcaccac ctagctggat
     8581 atttgggccg atgtggacct tactgtatat attgatgggt atttctcttt atttgttact
     8641 taatcacaac aacaaaaaac agcgaaacaa tcttgtcggt ctttttgtga ttcagttcat
     8701 ttttaatttt atatggtctg ctctattttt taatttaaga aatattttca ttgcagcaat
     8761 cgatattaca cttttagtta ttttcttgtc agtgcttatg tatcagttgt ggctgcatca
     8821 tcgcctggca atgtggctca tgattcctta ttatttatgg gtactattcg caactctatt
     8881 gaattattca atttattttt taaactaagc gctaaaaaga gacgtcctgt aatttaacac
     8941 atagaaaaag tgccacctaa gttagatttt ttgtctaatt taggtggcac tctttattaa
     9001 ccaaactatt tttttctagt acccacttgt tgttccatac tcattattct ggtcataacc
     9061 ataaccattt tgttcctgtc cagcgtaagg atcataactt tgagtatctt gacttggtgt
     9121 atagtactga cttgtatctt ctgtttgctg ataataggta ttcggatctt ggtactgatc
     9181 atatgtgttt tctgaatagg aagaataatc ggtgtaccct tcactattcg atccatcacc
     9241 gtttgtcgaa tcgccatctt ccgaatcatc aaagaacatc attgaagcat tctcattttt
     9301 caaattaggt aatgtatcgc ttgtttttat atttaattgt ttcttcagtt cattttggat
     9361 cgaaagaaga tcattttttc ctaaaatttg atagtagata tcattgatca tttgtccttc
     9421 gccttgcaac tggtcttgtt tgattgtttc aaacgccggg gtgtagttcg tcgctacatc
     9481 aagcatgtca tcccaatcta agtccgtcgt cacattgttc tcaactgctt ttaaaatttt
     9541 tctataattg cttacgccat ctaaacttaa aactttattg acgattttcg tcactacttc
     9601 ccgctgacga cgttgtcgac cgatatcgcc ttctggatct tcgtgtcgca ttcgagaata
     9661 ggctaaacct ttttctccat tcaatgtttg ttcacctact ggtacatgga caccatccaa
     9721 agtaaagtca attttattat tcactttgat gccaccgacc gcattgatca aatcttccat
     9781 gccatccaaa ttgatcgtta cataatgatc aataggaata tcgagcagtt gctcaattga
     9841 atccatggcc atttcgacac caccaaatgc gtaggcatga tttaatttat ctaccgttcc
     9901 ataacctacg atattcgtat aaatatctcg gtccaaactg atgatcgttg attttttttg
     9961 tttcggatta actgttacta ccatcatcgt atcagaacgt ccttgttccg ttcttcctaa
    10021 tccaccggta tctaaaccta atagcaaaac cgaaaaaggt tctttgtcat caatgcttac
    10081 tctctcagaa cgtttggagg atattcgatt agagttttta gaaattttgt ttactgtttg
    10141 gctcgcttct cccataaatc tgattccgta tgctgataat ccggcaatca gcaaaacgaa
    10201 tacccctaac aaggttaata gaactttttg ccatcgcttc ataatacacc tctgtttcac
    10261 attttctaaa atattgtctc atataactgt tcaatcagca aattcacttt ttaatcataa
//
LOCUS       DACDAF010000093        10243 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.096, whole genome shotgun sequence.
ACCESSION   DACDAF010000093 DACDAF010000000
VERSION     DACDAF010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10243
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.096"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            160..390
                     /locus_tag="IVZ69_002295"
     CDS             160..390
                     /locus_tag="IVZ69_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HAP8184332.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            487..1788
                     /gene="murA"
                     /locus_tag="IVZ69_002296"
     CDS             487..1788
                     /gene="murA"
                     /locus_tag="IVZ69_002296"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HAP8184333.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1801..1977
                     /locus_tag="IVZ69_002297"
     CDS             1801..1977
                     /locus_tag="IVZ69_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HAP8184334.1"
                     /translation="MSNQRYIILTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2112..2408
                     /gene="yidD"
                     /locus_tag="IVZ69_002298"
     CDS             2112..2408
                     /gene="yidD"
                     /locus_tag="IVZ69_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HAP8184335.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFQLTRNKKDKKEPDYKKVVKNTSSTER"
     gene            2592..3059
                     /locus_tag="IVZ69_002299"
     CDS             2592..3059
                     /locus_tag="IVZ69_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8184336.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVAPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3144..4028
                     /locus_tag="IVZ69_002300"
     CDS             3144..4028
                     /locus_tag="IVZ69_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP8184337.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNSYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4145..4378
                     /locus_tag="IVZ69_002301"
     CDS             4145..4378
                     /locus_tag="IVZ69_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HAP8184338.1"
                     /translation="MSKKNKDVEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYGP
                     KEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4466..4546
                     /locus_tag="IVZ69_002302"
     tRNA            4466..4546
                     /locus_tag="IVZ69_002302"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4500..4502,aa:Tyr,seq:gta)
     gene            4553..4624
                     /locus_tag="IVZ69_002303"
     tRNA            4553..4624
                     /locus_tag="IVZ69_002303"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4585..4587,aa:Gln,seq:ttg)
     gene            5139..5846
                     /locus_tag="IVZ69_002304"
     CDS             5139..5846
                     /locus_tag="IVZ69_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8184339.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5906..6550)
                     /locus_tag="IVZ69_002305"
     CDS             complement(5906..6550)
                     /locus_tag="IVZ69_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HAP8184340.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6677..6964
                     /locus_tag="IVZ69_002306"
     CDS             6677..6964
                     /locus_tag="IVZ69_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184341.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7072..7392
                     /locus_tag="IVZ69_002307"
     CDS             7072..7392
                     /locus_tag="IVZ69_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8184342.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7473..8786
                     /locus_tag="IVZ69_002308"
     CDS             7473..8786
                     /locus_tag="IVZ69_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HAP8184343.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLGNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEIAKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKML"
     gene            8783..9502
                     /locus_tag="IVZ69_002309"
     CDS             8783..9502
                     /locus_tag="IVZ69_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HAP8184344.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVKSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQVAQPKIIRTISLAR"
     gene            9630..10181
                     /gene="raiA"
                     /locus_tag="IVZ69_002310"
     CDS             9630..10181
                     /gene="raiA"
                     /locus_tag="IVZ69_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HAP8184345.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADATALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
BASE COUNT         3415 a         1693 c         2187 g         2948 t
ORIGIN      
        1 ttgtctcagt cccttttttt gcatattttt agcatttatt tcctaaaaaa tgtaagggga
       61 ttcctatatt tttaagtata cttgtttttc cttttataca ttttatggta ttatcatttt
      121 attagttatt ataaaacaat cgttagaaag gacgtcatta tgcaagtata cggaattgat
      181 gcggtgcttc gaatcgtgag tcatttggcg tttatctact tagccttctg gtctttacgt
      241 tcgttacgca ttgaaacttt tttcagacca atgcataata cgcaaattag aatggcaatc
      301 gtactttttt caattttttt agggtacact gcaagtaatt ttttcttaga agttatcgct
      361 ttatgccgaa atcttttcgt tagcctgtaa attttaaaaa aaggtactat tttaaaagca
      421 aggatgttat aatagaaaag attttgagta agtgtatgct cattggaatt ttttggaggg
      481 aacaacatgg aagagatcat cgtaagaggt ggcaatcaat taaatggaac agtaagaatt
      541 gaaggagcta aaaatgctgt tttgcctatt ttagctgcta gtttgttagc agaagaaggt
      601 attacgacat tagacaacgt tccgattctt tctgatgtct tcactatgaa tcaagtgatt
      661 cgtcacttaa acgtagatgt agattttgat gaacaaaaga atcaagtaac aatcgatgct
      721 tcaagacaat tagaaatcga agcgccttat gagtatgtta gtcaaatgcg tgcttcaatc
      781 gttgtgatgg gtccgctact tgccagaaat ggacatgcaa aagtagctat gcctggtgga
      841 tgtgcgattg gtaaacgacc aatcgatttg catttaaaag gatttcaagc tttaggagca
      901 aaaattattc aaaaaaacgg ctatatcgaa gcaattgcgg atgaattgat cggtaacacg
      961 atttatttag atttccctag tgtaggtgct actcaaaata tcatgatggc tgccgtaaaa
     1021 gcaaaaggaa caaccatcat tgaaaacgta gctcgcgaac cagaaatcgt tgatttagca
     1081 aacattttga ataaaatggg cgctcaagtc tatggagctg gtactgaaac aatgcgtatt
     1141 gaaggcgtgg atcatttaca tgcagtcaac cactcaatcg tacaagatcg tatcgaagca
     1201 ggtaccttta tggttgctgc tgcaatgaca caaggcaatg tgctgattgc agatgctatc
     1261 tctgaacata accgcccatt gatttctaaa ttgatcgaaa tgggtgcaga aatcattgaa
     1321 gaagaaggcg gagtccgtgt catcggacca aaacatatct tacctacaga tgtaaaaacg
     1381 atgcctcatc ctggtttccc tacagatatg caagctcaaa tgacagctat ccaattagtt
     1441 gcagaaggta caagtgtagt gactgaaaca gtgtttgaaa atcgtttcca acatttagaa
     1501 gagatgcgcc gtatgaacgc tcatgtcaaa atcgacggaa atgtagcaat catggatgga
     1561 aaccatgaat tgcaaggtgc agaagtatat gcaacagact tgcgggcagc agcagcatta
     1621 gttttagctg gcttgaaagc aaatggaatc acacgtgtgc gtaacttgaa ttatctagac
     1681 cgtggatatt ataatttcca tatcaaacta cagcaattag gtgcagacgt tgaacgtgta
     1741 gacatggatc aaacttctgc tgaaaaaaca gcacaaacga ttgcttaagg aagtggctga
     1801 atgagtaacc aacgatatat catattaact ttgataaaga ttttagtggt gatcttattg
     1861 cttatccttc tttttgtggc cggaacgatg atcggatatg gtgtcatcgg tggcggcaat
     1921 ccatttaaag tattccagcc aagtttgtgg attcatattc gagacttttt tcattgataa
     1981 ataagaatca cagtggttct agtcgatatg aagtgagcca tgaagcagaa catgacaaaa
     2041 gaaaacagaa gggaacgttg acgttagtcg cgatcccttt ttttagtaaa agaaaagaag
     2101 gaatctaatt gatgaagaag atattgattt atttagttag aggatatcag cgctttattt
     2161 cgcctgcatt tccacctagc tgccgttatt acccaacctg ttccaattat atgataaaag
     2221 caattcaaac ccatggtgca ctaaaaggga cggtaatggg gactgcacgg atcttacgct
     2281 gtcatccttt tgtcaaaggc ggtatcgatt atgtaccatt gacattccaa ttaacgcgaa
     2341 ataagaaaga taaaaaagaa ccagattata aaaaggttgt gaaaaatacg agtagcactg
     2401 agcgataaag aaacaatttg gaaaatagct tcttatattt tgcaaaattg tgagttattg
     2461 ccgaagtgtt ggattttgaa caccgtcaaa aaaaggttgt gaaaaatacg ggtagcactg
     2521 agcgataaag aaaaagagga aaattattgt caaagtaaca actccgcaac tacttatatg
     2581 ggggacaaaa aatgatcgaa gaactaaaca agaaagattt accatggtcc ttgttattag
     2641 atgcagatcc tgataaagaa aaagttcaag tatatgtttc cagagggagt ggctggatat
     2701 ggaaagaaaa agaaaaaaca ataggtgtac tgatctatgt ggcaagggaa aaagaatacg
     2761 aaatcgtcaa tgtagcagta gccccaacgt atcaaggaaa ggggattggc ggaaaattac
     2821 ttgagacagc ttttcagaag ctttcacaac tcgcttccag tcaaactcag atcatcatac
     2881 gaaccggcag tactagcagt gcggcgttac atctctatca aaaaatgggc tatgtggaga
     2941 ttggtcgagt caaagactat tttatccatc attactctga gcccattttt gaaaatggag
     3001 atcaattaag ggatcaagta attttagcaa ttcacttacc taaaaatagc tttaactaat
     3061 aaactttcaa ttcgagaaaa tgctttcaaa tgctaaatag atacattaca atagctttag
     3121 caaacaaaaa ggagaatatt tttatgggaa tattagtttt tgattttggt ggatcggctg
     3181 tcaaatatgg ttgttgggat ggcaaagaga ttaaaggtaa gggacaattt gcaacgcctg
     3241 aatcttggga agaaatgaaa gcgcaattat ttcaagttta taaaaaaata ctcgtttctt
     3301 ttgaagtcga aggaattgga atcagctctc ctggagtagt gaataatgag aaacaggtga
     3361 ttgagggaat cagtgcgatt ccttatattc atggatttaa tattttccga gatttggaaa
     3421 ctctgtttca actcccagta acgattgaaa atgacgccaa ctgtgccgga atggctgaat
     3481 tttatgaagg tgctgcccgt gattatcaag atgttgcttt tgttgtggca ggaactggga
     3541 ttggcggggc gttgttcacg aaaggacaaa tcaataaagg ggcacatctt tatggtggag
     3601 aatttgggtt gatgttctta aatggcgata agacattcag taaacttggt acagcggtac
     3661 agatggcttg gcgttattgt gaacgcaaag gtctcgataa aaattcttat accggaaaag
     3721 atgtctttga attagcagaa actggagatg caatagcaaa agaagaagtt gagagttttt
     3781 atacgtatct tacaaaggga ttattcagta ttcaattttc gtttgatcca gaagtgatcg
     3841 tattaggcgg cggtgtttct gcaaaagaag ggctcattga tgagatcaaa agccgaatga
     3901 agaagctgac agaacaattc gatctgcatg atttcgaacc gcagatttta ttatgtgaat
     3961 acagaaacga tgctaatctt gtaggtgcag cagcaaacta tctcgctgta cgtcaagggg
     4021 agaattaaga gctttagaga aggtgcagct tgcataaaag aagtgaatga aatgaatagg
     4081 agatttttac ctaaggaatg ttttatttgc tgcagtatga taaaatatct gagaggtgaa
     4141 aatgatgtca aaaaaaaata aagatgttga agtgcgtata gaagaagtga aaaaagatat
     4201 caaaggtaag aattatgaag tcactcagtt atttataggg aaaaaaatga ttggtgagat
     4261 cttagcctat gggccaaaag aatatgaaat tttctttggt gaagaagatt ttggaaaaga
     4321 aaaaagtctt gaaaatgcga tagaaacagt gattcgacac tggaatctgc acgaataaaa
     4381 aaatatcaaa aaaactttca ataaagggtt gcaaaaatct ggaaaattag gtattataac
     4441 taagtcaggt tgatacaaac ctttcggagg agtagcgaag tggctaaacg cgacggactg
     4501 taaatccgtt ccttagggtt cagtggttcg aatccactct cctccatttc attggggtat
     4561 agccaagcgg taaggcaagg gactttgact ccctcatgcg ttggttcgaa tccagctacc
     4621 ccagtatacc acaatcgtaa gctctcgtta gttcgagagc tctttttttt gctttgctac
     4681 cttgttcctt gaagattctg ctgatttaag atagagttaa gttaactaca agaattggag
     4741 ggatccacat gaaatggaaa gaaaaagtag acgaagcagc tgaaaagtta tatgatttgg
     4801 tcaaatcaga aaaatacaat attgaagtga atattccgaa aaaaggcgga aaagcggtcc
     4861 aggtaaaatc aaaacgccca acgaatcata caaaaaaatg gatggctaaa aaccgctaat
     4921 aataacaaaa gatccataag tcggcatttt catcgatttt agggtctttt gttattttct
     4981 aggttgaaca tatctaaaaa attgtttctg acaataggag taggaagaac gatgtgtgtc
     5041 taaatcctct gttgatggat agaaaccttt atctttttca gttgtgaatc aggtatatac
     5101 cagttataat agaagaaacg aaaggacggg tgtacgttat gtcgaatcaa ttacctgtat
     5161 atatacagat tcatgaccaa ttaaaaaatg aaatcgaaca aggtatatgg aaagtcggag
     5221 accgtcttcc ttcagaaaga gaattagcag tgaaattcaa tgtcagccgt atgacgttga
     5281 gacaagcaat tcaaaacttg gcagatgaag gaatcttaga aagaaagatc ggttcgggta
     5341 catatgttgc gcgagaaaaa gtacaagaaa aaatgtctgg tgcaacaagt tttacagaaa
     5401 ttatggaatc gcaaaatcga gtaccgtcta gtcggacaat ctcttatttc ttgacttcgc
     5461 caagctcaag tgaaatggaa aaactaaact tgagtaaaga tgacacgatc ttgcgaatgg
     5521 aacgtattcg tttcgcagat gatgtcccta tttgttttga agttgccagt gtgccacaaa
     5581 agctgatcga tggctacagc aaagcagaga ttactgaatc gttgtatcgc acgctagaag
     5641 aaaaaggcgg gaaaaagatc ggtccagcga atcaaacgat tactgctgtg ttggcttctg
     5701 agaaaattgc tgactattta gaggtaaaac gaggagatgc agttcttcgt ttgcgccaga
     5761 tttcttattt tgaagacggt acgccgtttg agtatgtgcg tacgcaatac gtaggaaatc
     5821 gttttgagtt ttatttggaa aaataaaaaa caggtgatcc ctgattcctt acttagaaat
     5881 aaaagagaat cagaatcacc tgtttttata tatgatcagt taccagttgc tcgtgataag
     5941 aaacaggacc ctcttcaaat tggacttgtc cgttcagcag ctcaatgatg gattctttaa
     6001 agtggtcagc acttttttca tctacagcac agatgacgct aacttgatca gtatattgga
     6061 tttcttttat aaaaaaatgt tggagttcaa gataattctg taattttcct agttgcggat
     6121 acgtgatcat cacagagatc tcctgttgca aggtaccttc tacgattcca atgtcagaca
     6181 atgcttgaga gacagcatga gtgtatgctc gtattaatcc gcctgtgccg agtttcgttc
     6241 ctccaaaata tcgagtgact actgcagcta cattgatcag ttgatttttt ttgaggactt
     6301 ccaacatcgg tacgccagcc gttccacttg gttctccatc atcgctgctt cgctggattt
     6361 catttttttc tccaatgatg aaggcgctgc agttatggtt cgctttccaa tgttcttttt
     6421 ttatttcttg aatgaaactt tttgcttggt cctctgattc tattcgtcta agagaacaga
     6481 taaagcgtga ttttttgatc tcaatctcac tttgtccatt ttcttttatt gtacgatagc
     6541 gctcgatcat cttgtcacct ctttttttca ttttctttat tcagtataaa taaagttcta
     6601 ggttgtttca acactgtaac ggttgcgcaa tcgctgtagt atgcgataat aaagacaaag
     6661 gtaggtggat ctggggatgc aggaacgaat gaaaaagtac gatgcaatta cgcattattt
     6721 gaagaacaat ggcggctctc aagtaacgtt gacctttacc caatttgacg aactgctgtt
     6781 tcccagtaac ggacttccca aaacagcaag ggaaagtaca gattggtggg caaatgatta
     6841 taaacaccct gaaaaaggtg cctatggctg gataaatgca ggctatgaag tagttgtcat
     6901 caatttggac aaagaatatg tcgtgttcaa taaattagtg aaatctagtt ggctatttga
     6961 ttaaataaac cgcgtttaga aaacgttgac aaatttcttt ctttttatat aatagagtaa
     7021 cagacgcgaa gaaaacgttt gcgtagtttg ttttaaaaag gagagaaaag tatggctaaa
     7081 aaaacaatca tgcttgtatg ttcggctggt atgagcacaa gtttactagt aacaaaaatg
     7141 caaaaagctg ctgaagcaaa aggaatcgac tcggatattt tcgctgtgtc cgcttctgac
     7201 gcagataaca atcttgcaaa taaagatgta gatgtactgt tattaggacc tcaagttcgc
     7261 tttatgaaag ctgattttga aaaacgtctg gaaccaaaag gcattccttt agacgtcatc
     7321 aatatggctg attatggtat gatgaatggc gaaaaagtgt tagatcaagc aatcacgctc
     7381 ataggtgaat aaatagaaca gtataactat cgaacaagcg atccaaaaaa tagatcgctt
     7441 gttttttcgt atattttttt agggcgaata atatgaatca tttttggggt agaaggcttc
     7501 tgacgagaga tattaaagca atagactgtg aggaggtaaa tttaccaaat tatgagaaga
     7561 tcgcagcagt ggaacgtttg ggcaactgga ttctttgtca tcgctgtgga atgaggacgt
     7621 ccgtcattga tggacagctt gcagattacg gttatttttg tacacattgt ctatatttag
     7681 ggcgatgcga cactcaacaa gatttatatt tgtttgatca gcctgaagca aaacctcgag
     7741 aagtcgtctt tttttggaca ggacagctta ctgaaaaaca aacggaaatc gcaaagagaa
     7801 tactttgcca ttcagaaaaa agacatcatc ttatttgggc tgtaacaggt gcagggaaaa
     7861 cagagatgct ttatcctatt ttagtggaaa ctttaaaagc tggaggaaga gtagcgattt
     7921 gtacaccgcg agtcgatgtt tgtaatgaat tgtttttacg ctatcgttat gtttttccag
     7981 aagaaaaaat cacgttgctc catgggaata cagcaacggc ttataccttt acttcttttg
     8041 ttatctgtac gattcatcag ctataccgtt tttatcggtc ctttgattta atagtgatcg
     8101 atgagatcga tgcgtttcct tataacgggg atgcaggatt agctcatgct gtgcaaacag
     8161 cgattaaacc agacggacga ttcatctact taagtgccac acctgataaa aagttactaa
     8221 aggaaatcaa gcagacgttt gacatccaca aacttgcttt gcgctttcat cggcgtttac
     8281 ttcctgaacc cgtcttggtt ttcatgaata attggcgaca aaaatgcaag aacaagaaga
     8341 agataaaatc tttggtgcgg atcattcatc aattaattaa agaaaaccat atccttttat
     8401 tttgtccaag tatcacgatg atgcatcgtt tgaaagccac acttcaagag gctcttccga
     8461 gatatgagat cacagatgtt tcttcaagag acaatcagcg ggcggaaaaa gtccagaaaa
     8521 tgcgagaagc aaaatatgac atactgttaa ccacgatgat ccttgaacgt ggagtcacat
     8581 ttgaaagaat atccgttatc gttttaggag cggatcatcc ggtttttact aaatcttctt
     8641 tggtacaaat cgcaggaaga gccgatcgta aagggcctta tacgaacagt caagtatact
     8701 ttttctatga agaaaaaact gcagctattc gaaaagcttg tcaggaaatc aaagaaatga
     8761 atgaagaagg gaagaagatg ctgtgaggtg cagttgctgc agtaaagata tcgtccaaaa
     8821 tttaacattc agcgagatta ttggtgtttc gaaatacaga ttacctcaga cttgttcagt
     8881 ttgtcgcgca caatttcatt tattggaaac aagaggctgt tctggctgtc aaaaaccaat
     8941 ccatttcaat ctagagagta cgaaaaagaa agtaaagtct attcccgttt actgcagtga
     9001 ctgtcaagaa tggaagaaga aatatccgac ctatgatttt cagcaccgtg ccttttttgt
     9061 gtacgatgaa aatatgaagg cctggctcaa tcaatacaag tttatgggag atatccgact
     9121 agcaggcacc tttgcatata aatggacgca gataaaaaaa gaatacccga catacatcta
     9181 ttgtccaata cctttatctg aaaaaaggcg aacagaaaga ggattcaatc aagtaagcga
     9241 gatgttgaaa gcagcaagaa ttccttttca gatgctactc aaaagagaga agcatctgct
     9301 ggctcaagca aaaaacacgc gaaaggaaag attggagatg cctcaacctt ttgaacttgc
     9361 agtcaccttt tctaagatac aaaataaaaa aatattgatt attgatgatg tctatacaac
     9421 aggacagact cttttccacg cagcagattg tttgcaggtc gcacagccga aaatcatccg
     9481 aaccatttct ttagcaagat gaattagatg tggaaatttg atagcgattt aatttgcaaa
     9541 taacctagag ttcgatataa tagaattaag aagagggaaa gagtggtcct tctccttctt
     9601 gattgtggta gacgaaaggg gtaattttta tgtttagata taatgtacgc ggcgaaaata
     9661 tcgaagtaac tgaagcgatt cgcgactacg ttgagaaaaa agtaggcaaa ctagaacgct
     9721 atttcagtga cgcacccgat gcaacggcgc atgtgaactt aaaagtttat acagaaaaaa
     9781 cagcaaaagt ggaagtaacg atcccattac cttatcttgt attacgtgcc gaagaaactt
     9841 ctccagattt atacgcaagt atcgatttgg ttgttgacaa attggaacgc caaatccgca
     9901 aattcaaaac aaaaattaat cgtaaatccc gtgaaacggg catgaatact gcagatgcta
     9961 ctgctttatt caatgaagag gacgaaaacg aaaatgattc tgaattagat atcgtacgta
    10021 cgaaacgcct ttcattgaaa ccaatggata gtgaagaagc agtcttacaa atgaacatgc
    10081 tgggacataa cttctttatt tttgaagatg cagaaacaaa tggtacaagt atcgtttacc
    10141 gccgtaaaga tggaaaatac ggactgattg aaacagactg atcagcctta cttaaataac
    10201 aacgaaaact tgcagcagct actgacagct gccgcaagtt ttt
//
LOCUS       DACDAF010000094        10081 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.097, whole genome shotgun sequence.
ACCESSION   DACDAF010000094 DACDAF010000000
VERSION     DACDAF010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10081)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10081)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10081
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.097"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            201..680
                     /locus_tag="IVZ69_002311"
     CDS             201..680
                     /locus_tag="IVZ69_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184346.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNMDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            713..2941
                     /locus_tag="IVZ69_002312"
     CDS             713..2941
                     /locus_tag="IVZ69_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA domain-containing protein"
                     /protein_id="HAP8184347.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKERTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            3070..4713
                     /locus_tag="IVZ69_002313"
     CDS             3070..4713
                     /locus_tag="IVZ69_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HAP8184348.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKHALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(4786..5331)
                     /locus_tag="IVZ69_002314"
     CDS             complement(4786..5331)
                     /locus_tag="IVZ69_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HAP8184349.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(5354..5839)
                     /locus_tag="IVZ69_002315"
     CDS             complement(5354..5839)
                     /locus_tag="IVZ69_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP8184350.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(5829..6641)
                     /locus_tag="IVZ69_002316"
     CDS             complement(5829..6641)
                     /locus_tag="IVZ69_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HAP8184351.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(6780..8312)
                     /locus_tag="IVZ69_002317"
     CDS             complement(6780..8312)
                     /locus_tag="IVZ69_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HAP8184352.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIPILYLMEQPALSVSQSFLD
                     KNEISYMTHTSGTTGIPKLICHSAHSMGWRTKWQKTVFTKISEKKLIAFHISPVHSRF
                     NIGISSLMSMGFPMMPLANAQSSKVVHMLEAHRPIALETHPNNFVQWRFTAKEHPEAF
                     SGIRYYHSTFDAINNQTMKTFLRTSMAQDAVFLQVYGQSECGPMILKAHTLESLKTSD
                     ARDMGVGLEDMTSARITDSVGNVLPENTDGHIQLLSKGRALTYYKEDARFQENVYGDW
                     WDSGDYGFMDKHGHLFLKDRQVDLIETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSP
                     QPIIALAPDKEMDWNRWWEQVHELPRLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQ
                     KS"
     gene            complement(8421..9452)
                     /locus_tag="IVZ69_002318"
     CDS             complement(8421..9452)
                     /locus_tag="IVZ69_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HAP8184353.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
BASE COUNT         3364 a         1854 c         1924 g         2939 t
ORIGIN      
        1 attccaacat catcttggac tttctacatg ttactaatga gcgtgtaaaa gaacgagatg
       61 gtgtttttat ttctatcaat gaagctcttt ttctttgcaa tcctcacttc aatcctctat
      121 aatgtcgcat atagtttagt aaatgagtaa actactaatt tacttattta ctaaaaataa
      181 aaggatgagg agttaaaata atggaaatac caacaaattt aaaacataaa ccagtaatcg
      241 ttgtagaaga ctatgataaa gttgatggaa gaaatgcatt aaatatggat gcaaaagggc
      301 tttcactggg ccttgctcag tggaatgatc gtggaaaagt cgatatctca ggcaaggtat
      361 ggcgacatac tggagaaaaa tggtcacgac agtcggaaga attaccaatc acacgtattt
      421 tagatttagc gatcttagct gcgcaaggaa gtttatactt ccaagatgct tatcgttatg
      481 aaaaatttta tgatccagaa aatccagtcg tagacatcat tggattacaa gggaaccgaa
      541 tgacggtaga agtagatacc aaaaatccaa agatcgatga agacatcatt ttgtattacg
      601 atacactaca aaaagacgga gaactgattg gggaacgatt ccgtatttta aaacgtcttt
      661 tagatgagct aggatattaa tagacagaga tgatcaaaag gggaagagaa gcatggagaa
      721 tttctcacta acagaaaacc gaaccttttc acggctagaa aagcaaatga tctggaagaa
      781 accgaaaagc catcggacaa gtgcagaaga atggcggatc gcctccgaaa tcaaagggaa
      841 ttggcaagat cctgaaatga aaatcagtaa cgtacttttg gaaggagatg ccgggtcggg
      901 gaagacacaa ttagccaaag cactatctgc tgatctgcaa cttccctata caaaagtgac
      961 ctgttttgca gatatggaca aatcagatgt tttcggagcc ttattacctg tagtagattc
     1021 taataaggaa caagaccaag aattactaga agctatttac caaacagata cacttgaagc
     1081 tgtactgaca ctgatccaga accattacgg cattgatcct ttttctgcta aagaaaaatt
     1141 agcagagcta gttcaaagga tcgaagctga ttatccagat gcaatccatt acagctatta
     1201 cccttctgaa atcgttcgag cgattgaaaa aggctattta ttagagattc aagagccgac
     1261 tgtcatccga gatgcctctg ttcttgtggc acttaactca gcgctcgaac caaatgggat
     1321 gttgaattta ccgacaggaa tcattcgtcg ccatccagat tgcgtcattg tgatcactac
     1381 aaatcgaaat taccaaggaa atcgcccatt aaatgaatct ttaagagatc ggatgcaaca
     1441 tgcggaaaaa atggatcttc ctgccttaga agtcatggca gaacgtgcga tggcgaaaac
     1501 tatgatccaa aaacaagaac ttctcttaaa gatggcagag attatccgtt tgttggatga
     1561 aactgcaaaa gctaacgcca tcaaaggtgt agcaggaatg cgttcttatt tttattgggc
     1621 aaatacctat aagcaaggac aagatttact ccagtcgatt tatccaaaag ttttgtataa
     1681 attatccact gattcagatg aattggcaat tcttgaacaa gctttgtctg acagtggatt
     1741 gctactggaa cttcaggaca tattgagaaa agaaaaatgg ggtcatcctc aatctgagca
     1801 tacaaaagaa agaaccatta gcgccgaaga agcaaatgaa cgaaacatca ctgaaaatgc
     1861 tgaagaaatt ctgcgcttag atgaaaagaa atcgttgtct gctgaagaac caaatgaggg
     1921 agaagagaaa caagaagaaa caatagaaaa aaacgagatt cctcctcaaa tgcaaaaaga
     1981 acgcagtagc gatatcgaag gaaaaaatca aaaagaacaa caaacaggag atgattctca
     2041 agaaatgtct gcttctgaca tggaagcaca tgataaggaa atcaagaagc aactgaataa
     2101 agaagcgcga caaatcatga aggaaacgat tcatgaaaaa gaaggtctca tcgttcaccg
     2161 accagctttc caaggaaaaa cgccggaagc acgtgagcta cacatgcaag taatgccaat
     2221 agtagaatca cttagccggc aaattttaga gttactggat aatgaacaaa cagagacgta
     2281 ccaaaaagga aaatacgaag gtcagcggtt caatgcaagc aaagtagcat atggtgattt
     2341 gagaaatttt gacaaaaaga acccgccaca tgagcaacct tctttagcgg tagctgtacg
     2401 gatcgatgaa tctgggtcaa tgatacggga tgatcggatc gaagcggcaa aaaaagcagc
     2461 gattgccatt gccgaatttt ctaagaaagt cgatatccca ttgttgattt acggagatac
     2521 agcagaccgt tcgtcaagag aaaagacttc tttgttttct tataaagaat ttgaagacgg
     2581 atttcaatgg ttaaatgaaa aattagtcac tatgaaacca aggcaaaaca atcgtgatgg
     2641 tgctgcactt cgtttagcag cagaaaaatt aaacagacaa tccgcaacaa ccaaactgtt
     2701 gcttaatatt agtgacggtc agccaaaagc attgccggat tatacaggca aaaaagcaaa
     2761 agaagatatc cagtctgttt tgaaagaata tgaacgtcaa ggaatcctat ttgtctccgc
     2821 agctattggc caagacaaag aagaaatcaa gtcgatctac ggtgaaagtc gttttgtaga
     2881 tattactgac ttgaatgaat ttcccaagca aatgattcaa ctgattgccc gctatctatg
     2941 ataaaataaa gctcaacgaa cgcacttagc agattcgttg agcttttcgt ttctagttac
     3001 cggtaacaag gatacttcta aaatagaatc ggttataatc aagagggacc gttaaaggag
     3061 tgaaacgata tgatacaaga acaaaaatgg tggaaagaag cagtaggcta tcaaatctat
     3121 cctgctagtt tcaaagatag caatggcgat ggtcaaggag acatcaatgg gatccgtgaa
     3181 aaacttaatt atttgaaaga tcttggtatc ggctttatct ggatcaatcc gatctatcaa
     3241 tctccatttg tcgataatgg ttatgacgta agtgactatc aagatataga agagagattc
     3301 ggaacgatgg aagattttga tttattgcta aaagaagcac atgaattagg gatcaaagtg
     3361 attatggatc ttgtcatcaa ccatagttcg gatcagcatc aatggtttga agaatcgaaa
     3421 aaatctaaag aaagcccgta tcgcgattat tacatttggg tcgacggggt agatggcaaa
     3481 gaaccgaata attggacatc gattttcggc ggttctgctt gggagtattc tcatgaaact
     3541 ggacagtatt atctgcatgt ttttgcaaaa gaacaaccag acttaaattg ggaaagcgag
     3601 aaattgaaag aagaactatt caatatgatc cgatggtggt tggataaagg gatagatgga
     3661 tttcgtttag atgcgatttc tcatgtaaaa aaagatgaat attcagtaaa agccacagag
     3721 aaccctttct caccctttca aaatgtctca ggaatcgaag aacatttgac cgatttgaaa
     3781 catgtttttg aagagtacga tatcatgact gtcggagaag caagtggtgt cactgcagaa
     3841 gaaggaccac aatgggtagg gaaagacggt tatttcgata tgatattcga atttgatcat
     3901 atccatatct ggcagcaaga aaaagaaggg caattagatg tccttaaatt gaaacatgca
     3961 ttaagcgctt ggcaaacttc attggatggt atcggatgga acgctttata tatggaaaac
     4021 catgatgttc ctcgtgccgt ttcagtgttt ggagatactc gtcccgattt ttgggctatg
     4081 tctgcaaaag caatcgctat gatgtatttc tttttgcaag gtacgccatt tatttatcaa
     4141 ggacaggaaa tcggaatgac gaatatgccc tttgaatcga tcgatcaagt tgatgcagta
     4201 gattcgaaaa gactttataa aaggctgctt gcggaaggta agacaagaga agaagcattg
     4261 gatatcattc gtgaaacaac gagagacaac agcaggacac ccatgcaatg gacttcggaa
     4321 caatatgctg gtttttctac acatgaacct tggctgatca ctaatccaaa taccaaaacg
     4381 atcaatgtag aacaacaaga atatgaacca gagtcggtcc tgcaattcta taagaacatg
     4441 atccgcatta gacaaaccaa taaaggtctg atatacggtt cttataaaga atatcttcat
     4501 gaacatccac aactttatgt ctatgaaaga tatttagaag atgaacaata tcttattatg
     4561 gtaaacttaa cagaatcact tgctgactat gaacttccaa aagaagcaga tcagtcctgg
     4621 acattactct tgtcaaattc ctctagcgga gaatttgaag ctaaaggcat actagcacct
     4681 tatgaagctc ggttatataa aacaaacaag taaaacttcc tcgttaaagt tcattagttg
     4741 gactttgcga ggaagttttt cagattgctc tgtcaattac tcatttcaat aattcgctct
     4801 aggaccaccg atatatttag gacgagagcg aagggctgtc acgtgagctt gtccaagggt
     4861 tttcaaacga ggtctgacag gtacttggac atgcttgata tgcataccga ttgatgtgtc
     4921 accgatatcg ataccggctt gtccaactac gtgttccact tcgacaggat cattgaactg
     4981 gtcaaaagca gcaacagaac aagcacctcc agcatgtagt gcaggaacaa cagagacaat
     5041 ttcgaaattt tttgcttctg ccactgttcg ttctactact aatgctcggt tcaaatgttc
     5101 acaaccttgg acagctagcg caatttcttt aggatccaac aactctttta acgtacggat
     5161 gatccattga ccaacttccg cactggaatt ttttccaata tgtcctccaa cgacttcgct
     5221 tgtgctgcat cctaaaacaa aaagatcacc ttttttcaag tgtgcctcag ccaatatgtc
     5281 attaactatt tcagtcaatt ggtcttttaa ttctttttct gacaacttca ttttctaaaa
     5341 ccttcttttt caattaatat tgcttccgtg cttgaatacg ttgaagactt gcagttatag
     5401 gaaaggcaag tcccattcca atcagatttt ggaagatgtt tcctggtata gaagccactc
     5461 cagccggcca atcatataaa atccaaccgg cgataccata gccgatgatc ataactaagc
     5521 ttcctaataa aagccctaat ccccacatac gagtagaaga tttgctgaaa gaaccagcaa
     5581 catatccttg taacccgtgg atcactaatg aaaaaactgc ccactgcgga tatcctgaaa
     5641 tcaaatcgat caatagacca ctggaagcac caacaactaa tccacccgtt ggaccataaa
     5701 gaaaagcagc ggtatagatc ccggcctcgc ataatgtcac aaatccattc gtagccggta
     5761 cagggatcaa aattgttaat gaaagggcaa ctgtcaacgc aatcagcata gcatagatcg
     5821 ttaattgctt agttttcatt tctcattcct cctttttgaa taccgccaga ccagacactt
     5881 ccggtatgat cgttcatcag cacgccatta gaaatacaat gggcaacaaa ttttttactt
     5941 tctgctactg ctttggtaaa atctgcccct aacacaagat tcgctgttat tgcagaagaa
     6001 aaggcacaac cggccccgtt tactgttgta gtgtcgattt ttttatgaga aaatacctca
     6061 taatgatcaa ttgaatagag aagatccaca gcttcatctc cagccatcct tgtgccgcct
     6121 ttgatcacaa tgttttttgt tcctgaagca gtgagttctt tagcgagatg gatcatttct
     6181 gttaacgaag agggaagagc ttgaccagaa agtaaagcag cttctgccaa attaggcgta
     6241 atcatcgtaa caagtggaaa aagttcttcg atgagctgcg aaatatacaa ttgattgatc
     6301 acagcttcag tttctttgaa tgccaaaaca gggtctaaaa tgattgggat attttgtttt
     6361 gtttttatga agtctcgaac aaccatgatt gcttcacttg aattcaataa cccaattttg
     6421 ataccatcta atgaagtcat tttatcaatc gaaactaact gtcgtttaag caattccaaa
     6481 gatatagatt ccagcataaa tcgctcatta atatctagtg cccctataga agtcaaggcg
     6541 cttagtccga atagaccaaa attctcaaaa gtttttaaat ctgtttggat tcctccacca
     6601 gcaaatggat cagaaccgcc aattgtcaag attcttttca taacattttc ctccatgaat
     6661 aagagtataa cgaaattttc aaaaaagaaa aacagccaat tggcatattt ttatctcatc
     6721 caatttaaaa aaacaaaaag aaaagaaaga ccaaaatgga tctttctttc cttaaatagt
     6781 taggactttt gtgattttaa ttctttctcg atttgaagcc gttgcacttt cattgtagct
     6841 gttcgcggga ttgcatcaaa atcacggatg atagggacgt tcaagcgagg aagttcatgg
     6901 acttgctccc accatcgatt ccaatccatt tctttatcag gagctaaagc aataatcggt
     6961 tgtggagaat gatttttatc ccttacaatc actacttctg ccaaaaaatc taacgaatct
     7021 aataaaaagt cttcaatagc taatgtacta ttgatcgttt cgatcaaatc cacttgccga
     7081 tctttcaaaa ataggtggcc atgcttatcc ataaaaccgt aatctccgct atcccaccaa
     7141 tcgccataaa cattttcctg gaaccgtgca tcttccttgt aataagtcaa agcccgtcct
     7201 ttagacagta attgtatatg accatctgtg ttttcaggta ggacattccc aactgaatct
     7261 gtaatccgag cgcttgtcat gtcttccagt ccaacgccca tatctcttgc atcacttgtt
     7321 ttcaaactct ctagtgtatg agccttaaga atcattggtc cgcattcact ttggccatat
     7381 acttgaagaa ataccgcatc ctgtgccatc gacgttcgca aaaatgtctt cattgtctgg
     7441 ttgtttatag catcaaaagt ggagtgatag tatcggatac ccgaaaaagc ttctggatgc
     7501 tccttagcag taaaacgcca ctgaacaaag ttattcggat gggtctctag tgcaattggc
     7561 cggtgagctt ccaacatatg aacaactttt gaactttgtg cgtttgctaa aggcatcata
     7621 ggaaatccca tggacatcaa agaagagata ccaatattga atctggaatg cactggagag
     7681 atgtgaaaag cgattaattt cttttccgaa atttttgtga aaactgtttt ttgccatttc
     7741 gtccgccatc ccatagaatg agcagaatga caaataagtt tagggatacc agttgtacca
     7801 gaagtatggg tcatataaga aatttcattt ttgtctaaaa atgattgaga aacagacaaa
     7861 gcaggttgtt ccattaaata aagaatagga atctgttttg attttgttcc atttgaaatt
     7921 tctctcactc gcttttttgt ctcatcatca aataaaatga aagggtcttc taaacgatcg
     7981 ataaatactt ccattgttgt tgttggtaga tgataagaag tcatgacagg cactgcacca
     8041 aggtaagaca cagaaacagc tagaaggtat gtgtcaaaag cggaactctt ataaataata
     8101 actttgtctc cggatttcac tccaagatga gccaattgat aagcccgttt caacacactt
     8161 tcgcagcatt ttttgtaagt tgtttcaagt cctaattctg ggaaagctga aagtggctca
     8221 tcaaagataa tcggggtctc ggaaaagtta gctgcagctt cttgaaaatt cgtaaataag
     8281 ttcaaagggg aatacgttat ggtctccatc attcacactc cattatcttt tgttaagtaa
     8341 tatacaaatt caagataatc gtaacataat cctttatata ataacatagt ttattgtgaa
     8401 aaaaagatca tacatttgtt ttatatggaa gaaacccgaa cgaatgccgc taattcgtga
     8461 taagaaaaat caaccatctt ttcccagata tcttgaaaag aatgggatga gaggtatcga
     8521 ttaccacata aataatttac cgcgtcagca tcatctaaat atagttctgc ataataacga
     8581 tatgtttttc tgcatagttc tggcgatacg tttttatata ctgtaatttt gctcaaaatt
     8641 tggcgaatag tccgaggaga aatttgctga tcatgtgagg aacgaaaaac aaaagaattt
     8701 tcgtccgtat tttgtgctgt taacttaaaa tagttctcca gaaatggcat cgcttctttt
     8761 ggtattggta ctttattcag tctgttttct tttctattca gattaagaat ctgcttggtc
     8821 aaagatacat ctttacgttt aagttctact acttcatgga tctttaatcc gcaatacaga
     8881 agaatggcag taattgcaag gttcctcggt ctattctttt cttcaaagct agcttctctg
     8941 cttgtttgaa agccttcaat cgggataaac aaatgctcaa aatctttgaa aagttctgca
     9001 tcgatatatc gcggagctgc tttggttgtt tccggtaaac ttgtacccaa aagagaaatc
     9061 tcttcttcaa tcagtccttt ttgatacaaa aatcgtaaaa aatgatttaa tgaatattgc
     9121 ttccttgaaa tcccgtaata gctattttca aacaattgct ccgtttcttg gttcgctgta
     9181 gtttggaacg aacgagtatg tcgatagatt ttagctaaga aattctgata atcttgtttt
     9241 tctaaatgga taatcagctg atcatccact tcttcagaaa atacttttct caaataatca
     9301 gtaaacagat gaaaatcttt tgcgtattca tagcgactgc ctaatgaaag ggaagaacga
     9361 ttttcttcta aaaactgttg aaagacggaa gggagcaagt gtgtacgttg ctttaacttt
     9421 tcttgcagtt gttttctagt tttgctgtcc attacaaatt ccctccaata gtgttcattt
     9481 tctatatttt accgcatttc atcaaatgaa gatagacagt ttgtcttgat cttaggaagc
     9541 aaatttttaa ctaagtacta gctaaaagat atgaagtaag aagatacatt tttagttatt
     9601 ttattagtgc agtcattctt ttgatctttt aattgattta tcctcttttt agctatgtgg
     9661 ttacttcatg agcaatgaaa tggatttggt tcgttctaat ggcaggaggc tctttctttt
     9721 atttccgaaa aattagaaaa cattttttca gaatcgattg gctctccatt tattcaataa
     9781 tggtttgtct aacgatattg ttgggataat tcttaaagaa gtattagaaa tagttggtac
     9841 ttcattactt tacatgaaga tttattctat ggtaggagca attatattga gaattaatcc
     9901 ttttttatat aagttgtttg cttattgatg gattggataa attaaaccat cacaacgagt
     9961 ggaaattata tgaaattttt cataaaaatt catatagaaa caaatgacat tttattagaa
    10021 tatgactttc attaacataa atgttttcaa atttcaatta aattgtttta atcaaattcc
    10081 a
//
LOCUS       DACDAF010000095        10034 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.098, whole genome shotgun sequence.
ACCESSION   DACDAF010000095 DACDAF010000000
VERSION     DACDAF010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10034)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10034)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10034
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.098"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(498..722)
                     /locus_tag="IVZ69_002319"
     CDS             complement(498..722)
                     /locus_tag="IVZ69_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184354.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            922..3690
                     /locus_tag="IVZ69_002320"
     CDS             922..3690
                     /locus_tag="IVZ69_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8184355.1"
                     /translation="MLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNTVSH
                     YLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQPKDL
                     FSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLHDLL
                     EDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLDEVH
                     RLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRIPIR
                     IELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGELKNI
                     VKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLMEKQ
                     QPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHELLVY
                     WTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELEQQV
                     SQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIAAHG
                     YATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILVDMG
                     SLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPEWRL
                     LYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNSDPL
                     FSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQRII
                     RNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLIERL
                     IRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSEDTE
                     FLSIEEEF"
     gene            3771..4190
                     /locus_tag="IVZ69_002321"
     CDS             3771..4190
                     /locus_tag="IVZ69_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HAP8184356.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            4202..4672
                     /locus_tag="IVZ69_002322"
     CDS             4202..4672
                     /locus_tag="IVZ69_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8184357.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            4689..5468
                     /locus_tag="IVZ69_002323"
     CDS             4689..5468
                     /locus_tag="IVZ69_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8184358.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            5455..6276
                     /locus_tag="IVZ69_002324"
     CDS             5455..6276
                     /locus_tag="IVZ69_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP8184359.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            6293..7342
                     /locus_tag="IVZ69_002325"
     CDS             6293..7342
                     /locus_tag="IVZ69_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP8184360.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            7355..8359
                     /locus_tag="IVZ69_002326"
     CDS             7355..8359
                     /locus_tag="IVZ69_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP8184361.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            8992..10011
                     /locus_tag="IVZ69_002327"
     CDS             8992..10011
                     /locus_tag="IVZ69_002327"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HAP8184362.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         3363 a         1653 c         2094 g         2924 t
ORIGIN      
        1 ttacttcttt tttaatttgt tcttgcaatc ttttttgcta cgtaattttt gtaaaaaagt
       61 gggttgagag aaatctaatt gattttcaaa gaaggagtat gaaaatgaga aaaatattta
      121 ttcgtttatt gtgggtacta tcttagagga ataaataata gtggagaaaa ctatggtttg
      181 gcgcagattc tatcaggttt gatggaacga agacaacctc ccgacatcaa gtcaaaagct
      241 acttgagatt ttgatctgaa aataaaaaaa gaaaacaagg taggaacatc aatgtttcta
      301 ccttgttttc gtaatcaatg ggaaaaaact aagagtggtg tacgtaatca ataaaaagga
      361 tggtgacaac agtacctctt tactctctga aagcatcata actcgttttt cctcattatg
      421 ccaataaatt gttgttatac cacatataag gatttgtaat agctaaaaac agacaggaaa
      481 gttgaaatct gtgaatctta ttttgtatgg aaggatttat agaacgcaaa aatcaagata
      541 aagatgaata aaaatcctgt ttcggctata tattgcgtat ctacgccaat aaaacgagtt
      601 tgttctgtca tagccatata aagcaaaggc aaaaatacaa ctacagcgag ataagatccg
      661 atgatttctc gaaaagtttt ccaggaagta tgtttcctgt ttttatattt atccgatttc
      721 attgaatagt catagcctcc ttattctttc atatgttgaa attccagtat aaaaactgga
      781 aggaactgta cgttttttag aataaaaatt ataagggata agtaggctgc tgtctataat
      841 aagatatatt tttcaattct ttattaaaga ttttattgac aaaatgaatc cgttttctat
      901 gatggaggag gggtgaataa gttgttgaag aaggaaattt tatgttactt agagaaccag
      961 acagcctttt tcgatttaga acatatgaac gaggtcttta cagcacaaag gttagctgat
     1021 cattttgggg taaaaagaaa cacagtcagt cattatttga accagttaaa tgatgagcaa
     1081 ctactagtca aaatcaattc tcgaccagtg atttatttcc acaaagaagc ttttgaaaaa
     1141 caatttttta agttacgcac gaatttttat ttttctatcg atgatctcaa agaggaacag
     1201 ccttttttcg cgcaaccaaa agacttattc tcttttatga tcggatacga cgccagtttg
     1261 aaagaaagta tcgaacaaat caaaacagct ctttactatc cagatggcgg attaccactt
     1321 ttgattacag gcgaaagtgg cacaggtaaa agttatttag ttaatttggt ctatcagtat
     1381 tgtctgcttc atgatctgct agaagattct gcaccattca tcacttttaa ttgtgcacaa
     1441 tatgcagata atcctgaact tttgactagc aatttgtttg gacatgttaa gggagcgtac
     1501 actggtgcag aagaaaataa aaaaggggct tttgaagcag cagatggtgg gatcttgttt
     1561 ttagacgagg tacatcgctt aacaccagaa ggtcaggaaa aactgttcac ctatcttgat
     1621 caaggtgtga tttatcgtat gggagaacct aatttgtcac gccggatcaa aacacgtctc
     1681 ttttttgcta cgactgaaga gattactagt catttcttaa caactttcat tcgaagaata
     1741 cctatccgaa tcgaactacc tgcacttaat cagcgtagtc gtaatgaacg gctagaactg
     1801 atttactctt tttttctcga agaacaaaga aaaatgggga gccctttgtc agtcagtgga
     1861 ccagctttgt cacttttaac aagtcagaaa ttatccggaa acataggaga gctgaaaaat
     1921 atcgtcaaag tttcagcagc aaaagcatat gctgaacagc gtgaacagcc tgaaatccat
     1981 gtcacgatcc atcatttgca aaaagaacta cttgcgcagc ctattactaa aaatacagca
     2041 cagcaaggaa tctatattac gcaagaccag accttagagc aattaatgga gaagcaacag
     2101 cccgaacagc agcgaatcgt taaaagtttt gagcaaatcc taattgattt caagaaaaat
     2161 aactgtctgc tatattcttg cgaaggaaaa ttaaagcaag aagtgattca attatttgat
     2221 tttttgctgt ttgagaccag tagacaagaa aaacacgagc tgctggttta ttggacacaa
     2281 tctatccgag agacctttcg acaaatggaa actgcctatc aaatcaaatt cgatggaaac
     2341 agtgtctatg ccttgagtta ctatctctat cagcgaagca ctatcaaatg gttaccggaa
     2401 gaacatgata ttatccaact aatcaaagaa ttagaacaac aagtttctca gtcttatcca
     2461 tctagttatc actatgtcca acgaattctg gaattaagta agatcaaatt agatattgaa
     2521 gacacaagta tggatcggat tttactgacg atctatctaa aaaaagcgaa atggtcaaaa
     2581 gaaaaacgac tgccaaaagc gatgattgct gctcacggtt atgcaactgc tagcagtatg
     2641 gcaaatgtag taaatcgttt attacaagag gatctatttg aatcatttga tatgccacta
     2701 gatgtcacac cacagcagat tgcttcagaa atccttgatt attgcgaaaa cagcgatgtt
     2761 tcaaatggat tgatcatatt agtagacatg ggatctctga aagaaatcca tcagtttttt
     2821 aaaaaacagt tatccgtacc gcttttgatt ttgaataatg tgacgacacc tttagcaatc
     2881 acagtagggg aatgcctgca aaaaaatgta tcattagaag agatagcaga agagactgtt
     2941 cgacagatcc agccagaatg gcgactgctc tatccagagg aaaacaaacc caaagcactc
     3001 attactactt gcttcactgg aatcggtacg gcggtccact taagtgaact gctagaaaaa
     3061 agcttaccta cggcttgtca gttgaaaatc atcccatatg aatatcagca attaaaagat
     3121 aagaaaaaca gtgacccatt attttccata tacgaagtcg taggaatgat tggcaccaca
     3181 gatcctgata tcaccaatat cgactatctt tcattagaag acctcatctc gggggaaaag
     3241 atgtctgtac tagctgaatg gttggacact actatgaatg cttcagagaa ggaaatattc
     3301 aatcagcgca tcattcgtaa tttttcattg gaaaaagtac tggattccgt gactattcta
     3361 gatacagaga aggtgatggg agaaatcgat cattttatga gagaattaga ggtgcagttg
     3421 aatcgaagca tcagcaatcc caaaaaatta gcgttgtatg tccatgtgag ctgtctcatt
     3481 gaacgattga tccgacaaat gccaatcgaa acctatcaag gattagagaa atggaagcag
     3541 tgtcaaaaag aagggttatc tgctattaaa tctgcgttta gtgtcattga agagcattat
     3601 agtgtcatga tccccaattc tgagattgcc tatatctatg atattttgag tgaagataca
     3661 gagtttctct cgatagaaga agaattttga acataagcaa gttgttgcca ctaattttgg
     3721 catgcaactt gcttttttag tatgtgtaag tgaaaagagg agatgaaaaa gtggatagag
     3781 aaattatctt agcttcccat ggaaaatttg cttcagggat attagattca ttagagctga
     3841 tctatgggaa aaatcattct attactgtat tcgattgcta tactgatgag aattttgatt
     3901 tagcggaaac agtaaggcag ctttttatga ggtacaaaga taaagaaatc attgttctga
     3961 cggatctttt tggcggaagt gtcaacaacg aattcttaca atatatcaat cgggatcatg
     4021 tctatctcgt tgccggattg aatttgccac tattgattga gctagtatct cggttggacg
     4081 ctgaagtaga gacaactgtt ttgatccagc aggtgctaac tgattcaaaa aaaatgatcc
     4141 agttttgtaa cgagcggctc aatcagaaaa tagaagaaga cgaattttag gaggaagaaa
     4201 aatgattgta ttgacaagag tcgaccatcg gttattacac ggacaagtag ctttttcatg
     4261 gacacaaaca ataggcgcag actgtatttt gattgctaat gatgatgtac ctacgaatga
     4321 gatacgaaag acaacgatca aattagccaa gccacaagga gtcaaactag tgatcaaatc
     4381 aattgatgac tcgattgccg cgttgaaaag cggggtgaca gataaatata agttattcat
     4441 cgtagtggaa tcgatcgagg atgcatataa gctggcagaa gcgtatccag aaatcaaaac
     4501 catcaactta ggagggatca aggcaaaacc tggtactcgc agcatcggaa aagcggtaaa
     4561 tattttacca gaagaggagg aacgcttgaa acgattaatt gacaaacaaa tagaagtaga
     4621 aatccgtcaa gtaccagcag ataaaaaagt ggatgtaaga gaagttttgt aagaaaggaa
     4681 gaacctcaat gattgtacaa gcagtcttat taggaattgt tgcatttgtc gcacaatcag
     4741 aatatgcact agggacatcg ttgctttctc gtccgattgt gacggggctg tttacaggaa
     4801 tcgtgttagg tgatgtaaaa actgggatca ttatgggcgc aactttagag ttagcattta
     4861 tcggatcgtt ctcagtaggt gcttcgattc cacctgatgt tgtgaccggt gggattttag
     4921 ggacggcttt tgctattaca gctggagccg gtacagaaac cgcgctttta ctaggtttgc
     4981 cgattgctac gttgacattg atattgaaaa atatttactt agggcttttg attccaatta
     5041 tgaaccataa agcagacaat tatgcagaag aaggaaatta taaaggagtc gagcatatgc
     5101 acttgcttgc cggtatcggt ctttccttga tgcttggtgt tgtggtaatg gtttcttata
     5161 tggtgggaag caatacgatc ggaaatctat taaatatgat tcctgacttc gttcaaaagg
     5221 ggttgtcagt agctacaggg ttgattccag ctcttggttt tgcgatgctt gctcgtttgc
     5281 tgatcaacaa acaagttgca ccatattttt tcttaggttt tgctatagct tcttacttag
     5341 agattcctgt gaccggagta gctatttttg gtgcgatttt agcagttgtg gtagtcaata
     5401 ttatgaatgt ccgtcaacta ccacttcaaa caactgcagg ggaggtagaa gaagatgaag
     5461 aattctgaga tcaaaaacag caaaataacg aaaaaagagc taaatcacgt attttggcgt
     5521 tcttttcaaa tggagttttc ttggaattat gaacgtcaga tgaatatggc ttatgtttat
     5581 gcaatgattc cgattttgaa aaagttatat cagtcgaaag aagaaatggc agcagctttg
     5641 aaacggcatc tagagttttt taacacgacc ccacatatcg ttacactgat tttaggaatc
     5701 acggctgcaa tggaggaaga aaataaggat gatcctgaat ttgatgtgac tgcgatcgat
     5761 agtatcaaaa catctttgat gggacctctt gcagggttag gagattcttt cttttgggga
     5821 actttgcgat tgattgccac aggtgtgggt acctctttag ccatgcaagg aaatatttta
     5881 ggccctatct tgttcatttt gattttcaat attccgcaca ttctgtttcg ctatctagca
     5941 acaggttggg gatatcgctt aggaacgggt tttttgaaaa agatccaggc aaacggtatg
     6001 atggaaagtt tgacattagg cgcgtctatt attggactga tggtcgttgg agcaatgact
     6061 gccacgatga tcaccatcaa tattccttta aaaatcggtt caggagaaaa tgctgtgact
     6121 gttcaaagta tttttgatga tatcgttcca aatatcttat gtcttggagc atttggcata
     6181 gtgttttatc tattgaagaa agaagtgaaa ccattaacga tcttgatcgg actagctttc
     6241 tttggaattt ttggttcgtg gatagggatt ttttaaaaaa ggagcagaga aaatgtttac
     6301 gatgcaagat tatatctatg aagaaaagga agtactaagt acgatcttga aaaagaatga
     6361 tttttcgaca agagaacata tgaaaaaaac agtgaattta ctgatcttag caacgggttc
     6421 atcttataac gcttgtttag cagcgaagcc agcattggaa tcttatggtg atcttactgt
     6481 cgatattcaa gaaccttttt attttttcaa ttatggaaaa ctttctcctt caatcgatac
     6541 tgtgattgct gtgtcacaaa gcgggaaaag tgcttctact gttgaagcag taaaaatgat
     6601 acaaaaacaa gggttacctg ttgttgctat cacaaatgac gtgcaaagtc cacttgcttt
     6661 agaagctgca caaattattg atttaggtgc cggggtagaa tcagtaggct tcgttacaaa
     6721 aggctattct gcgactgttt tacagttact actcttaggg ataggaattg gaataagtaa
     6781 aaataaaatc agcaaaaaaa tagaacaaga ctacatgcaa cagttgcgca aaataatcaa
     6841 ccatttacca gcgattattc aaaaaacgga agaatttttt gatggatatc aaagtttatt
     6901 tcgtttagca cagcgtttcg tcaccattgg atatggtcca aactggggaa cagctaaaga
     6961 agcagagacg aaattgactg aaacaatccg cgttccgtca caaggatttg agttagaagc
     7021 ttatatgcac ggcccatacc tggaggcaga tgcttcgcat ttgctattct ttattgaagg
     7081 ggaaagtgta aataaggaac gttcgcaaaa gttgcaaaga tatatgagtc ggtacgttgg
     7141 agagactctc accattacca caaaaaaagc aagaaacgag aaaacacttg gattagcaat
     7201 agaatgtgat gaatatctgt ctgtattagc gcttgtcgtt ccgtttcaac tattcgctta
     7261 taaaaccgca gtagctaaag gtattgactt gaacaaaaag atttttgaag actttgatac
     7321 agtcttgaaa agtaaattat aagaggtgga aatcatgctg aaattcaatg aagaagaaca
     7381 aatcaaagca ataaaaggcg cactagcttt acgtccgcaa gtagaagaaa tcatcgataa
     7441 actttatgcg gaaaaatttg acgctgtcta ttatctagga atcggtggaa cgtatgcttc
     7501 ctcgatgcaa gctgtcactt atatgaatgg gaaaagcaac ttgcctgtct ttgtacagca
     7561 tgctgcagaa tattacacta ctggaaacaa aagattaaca aaagattcta tcgttatttt
     7621 gtcctctgtt accggtacaa ctcaagaagt agtgaaagca gtagaacaaa tcaagaaagt
     7681 aggagcgaca ctgattggat ttatcgataa agcgaacagt aagttgtctc agctatgcga
     7741 ttttgtggtc acttatccag ctcctggaac agaacaaatc aaatttttta tggcagcaga
     7801 tcgattgatg tatttgaatg gagaattcga agcttattca gaatactatg aacagctcga
     7861 acgttattta ccaacagggt tagtggaagc agagaaaaaa gcagatgcat ttggcttatc
     7921 atttgcagaa aaacatcgac gtgatagtat gcattatttt attggagcag ggaatcaatg
     7981 gggagctgtt tattcatatg ccatgtgtta ctgggaagaa caaagctggc ttccatcgaa
     8041 atctatccat gctgccgagt ttcttcacgg gacgttagag atcgtagaag aaacaacccc
     8101 agtcacatta tttttaggcg aagatgaaca gagagtgtta tctgaacgtg tggctaaact
     8161 tttgccaaaa atttgcagca attatacatt gatagacaca aaagactatc cagtagaagg
     8221 tatcagtgaa aaatatcgcg gacgtgtttt gtctttctta ttgatgcatg tagtgacaca
     8281 acgcatcgat gctcatgtgg agcagttgaa ctgccatcca ttagagatac gccgctacta
     8341 tcgtcagttt gattattagg atagactgga taaaaagaat ataaaaaata aagagagcag
     8401 cgataactgc tccctttatt tttttaaaat attggcatca attacgttat aaaacacatt
     8461 ttttgcatta tctacagttc aacttataat ctgtttaatg ggacatgtgg gtgccaacca
     8521 ttttttgtta tgcaatagta ctatttagtt gttgcatgga tccgtagtaa aagtccaagt
     8581 acaacgagtt gcgccagttt acatagcgtt ttgtatccag aatgttgact aaaacaaaag
     8641 ttcctatgtc aaccgtcaac agagacaatc tgtccgttgc aggacctgac agatttagaa
     8701 atgttcaatc tgtctcttat gtattttaaa tcaatactca ctaggagaag tttcctaacc
     8761 tcctaatagt aatgctggta gtaacattgt caaaactgct tcctcttagg aacaagcaaa
     8821 gcataacgag tgtaaaaata aaatgtagac tattgtaaca tatcattgat tatttcaagt
     8881 aaaaacgata aaagaagtaa acaaacactt aaaaacaatg gaaattagtc ccaactttaa
     8941 gaaatgtata ctataatgga aattatcaat tatttatttg gaggaatatc catgaaacaa
     9001 aaaatcgcag ttcttggtcc tggatcttgg ggcactgctt tagcacaaac attggcagaa
     9061 aacgggcatg atgtccgtat ttggggaaat gtacctgaac agattgatga aatcaataag
     9121 tatcatacaa atcagcattt tttacctgat ttgacgatcc cagaatcgat tatcggatat
     9181 aaagaattgg cagaagcagt ggataacgca gatgctattt tatttgttgt tccaacaaaa
     9241 gcgattcgtt cagtcgcaca ggaacttatt ggtaaaatga atactaagcc aatcattata
     9301 catgcaagta aaggactaga acaagatacg cataaacgaa tctcagaagt tttggctgaa
     9361 gaaattccag aagaaaaaag acaggcaatt gttgtattat ctggtcctag ccatgctgag
     9421 gaagtggcag tacatgatat cacaacaatt acagctgcaa gtattgatca aaaagcagca
     9481 gcctatgtac aaaaactgtt catgaatgat tatttcagga tttatacaaa taatgatgtg
     9541 attggcgtag aaactggtgc agcactgaaa aatatcattg caattggtgc cggcgctatc
     9601 catggattag gattcggaga tgatgcaaaa gcagcaatca tgactcgagg attggcagaa
     9661 atcagccgtc ttggtgtcgc gatgggtgcc aatcctctga catttatcgg tttgagtggt
     9721 gtgggggact tgatcgttac ttgtacaagt gttcattctc gcaattggcg tgccggtaac
     9781 ttgttaggac agggacataa gctggaagaa gttctagaaa acatgggaat ggtcgttgag
     9841 ggtgtggcaa cgacaaaagc agcagtagag ctagctcaac agctaggtgt tgagatgcca
     9901 attactcaaa caatctataa tgttttgtat aatggagaag atatcaaaaa agcagcaaaa
     9961 gaaatcatgt tacgtgacgg aaaaatggag aatgaatttt ctcttcgtta aatagatgat
    10021 caatagttaa tcgt
//
LOCUS       DACDAF010000096         9989 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.099, whole genome shotgun sequence.
ACCESSION   DACDAF010000096 DACDAF010000000
VERSION     DACDAF010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9989
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.099"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..523
                     /locus_tag="IVZ69_002328"
     CDS             <1..523
                     /locus_tag="IVZ69_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP8184363.1"
                     /translation="EKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTIS
                     NEINQYREREPEIQPAEVKQEHKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTL
                     HLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNE
                     IYYEQQLSQKERV"
     gene            584..2044
                     /locus_tag="IVZ69_002329"
     CDS             584..2044
                     /locus_tag="IVZ69_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HAP8184364.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQLKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFIPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2055..4259
                     /gene="topB"
                     /locus_tag="IVZ69_002330"
     CDS             2055..4259
                     /gene="topB"
                     /locus_tag="IVZ69_002330"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP8184365.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAESIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ENDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            4498..5091
                     /locus_tag="IVZ69_002331"
     CDS             4498..5091
                     /locus_tag="IVZ69_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HAP8184366.1"
                     /translation="MKDKIQCIFDKHNGNLSLKDARSEGLSPMTLDRLAEKDKIEKVA
                     PGFYTLKDAFVDELYLAQSIYSRGIFSHETALDLFQVGTYIPKKINMMFPKGYNVSKE
                     KLDQYAIQPHYTNKENFDLGVTETESFYGNKILVYDLERTLCDMWNPRYKASVEVKQE
                     ALKEYMTSTSRNTNKLRRYMDILKSPKEMTLYMLPLY"
     gene            5107..6006
                     /locus_tag="IVZ69_002332"
     CDS             5107..6006
                     /locus_tag="IVZ69_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAP8184367.1"
                     /translation="MTPTQFKEKTRNFAAEKHLNPQIVQRYYMMEKLLECIVESPYHD
                     DFVLKGGFLIGSKYGLENRSTVDIDTTYRNSKLTKEKLETVFSELTANPTKDGIRFEL
                     KGLTETREADYYPGFQAKFIAYLENARVPFKLDITSGDSIIPAALMYEHKLMFEDKTI
                     HIPAYPTEQILAEKLHATFSFGKDNSRMKDFYDLYMIPKLERIDEKNLYKSVQGTFKE
                     RNNQSVFKHLYDQEMPQLVKDEGLREKWKRYQQENYFAKDISFESTLTSVDSLMQSIV
                     EQEKAERKQNFKRSQQMNQEMER"
     gene            6009..6494
                     /gene="ssb"
                     /locus_tag="IVZ69_002333"
     CDS             6009..6494
                     /gene="ssb"
                     /locus_tag="IVZ69_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP8184368.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFSLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRMHADQSSSSPSPTTFEQRDTATPNNNGLNASQNPFGGQSIDISDDDLP
                     F"
     gene            6860..7120
                     /locus_tag="IVZ69_002334"
     CDS             6860..7120
                     /locus_tag="IVZ69_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184369.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            7561..7767
                     /locus_tag="IVZ69_002335"
     CDS             7561..7767
                     /locus_tag="IVZ69_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP8184370.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            7767..8018
                     /locus_tag="IVZ69_002336"
     CDS             7767..8018
                     /locus_tag="IVZ69_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184371.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYEIEYWLTKLEN"
     gene            8033..8470
                     /locus_tag="IVZ69_002337"
     CDS             8033..8470
                     /locus_tag="IVZ69_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184372.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKEKLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFAQIKKAKAMASDWLDTFESIEKNGAFYTIESEEKDNE"
     gene            8463..9170
                     /locus_tag="IVZ69_002338"
     CDS             8463..9170
                     /locus_tag="IVZ69_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184373.1"
                     /translation="MNKVVYQLTTEDVSQFLTSKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYMESETSQTKVTVSHNHLDVYKRRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATVDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKGK"
     gene            9551..9730
                     /locus_tag="IVZ69_002339"
     CDS             9551..9730
                     /locus_tag="IVZ69_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184374.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
BASE COUNT         3654 a         1689 c         2057 g         2589 t
ORIGIN      
        1 ggagaaagct attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa
       61 ggaagcggcg gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat
      121 tcaaaccatt tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc
      181 agaagtgaag caggagcata aaaatactgt agaaacggca gagaataaga atattgtgcc
      241 cgttggttca ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg
      301 aacgttacat ttgaaggatg cggcgtttat tgaagatccg cagcataatc aagtgatttt
      361 aaaaggaaaa agttatggaa aagagattca aacggcgtta ccttcagaag aatttgcgct
      421 aggaaatcca ttccgatttt cacttgaaac agtgtcagaa gtggccaaac gaaaaaatga
      481 aatctattat gaacaacaat tgtcacaaaa agaacgcgta taaaacaagt aaaaaagact
      541 atctgaaaaa cggatagtct tttttctttt gggaggtttg aaaatgaccg aaaaaaaaat
      601 gagtcttatt gatcgatgta aacagatcga tatagtggat tttgctcgaa acaatggaat
      661 ggctgtagtc aataaaggac gagactatcg cttagaagac catgattcat ttgtttttga
      721 tcgaagaaaa caacgttttt attggaacag tcaaaatatt agtggcgaca ttattgaatt
      781 agctaaactt tttttcatag acaaagagat ccaagactct aagcaacaat ttaaagcagc
      841 cactgatttt attctaaaga atgaagacaa aacagaacga gtggaaaatc ttcattttga
      901 aacagaaaag tacaaagatc accccgttga ttatcaacca ctcacagaaa aaggaaggaa
      961 ttatctgaag gaagaacgaa aactaccaga gtggctgatt gattatgcag aaaaagaagg
     1021 gttgattgcc gaactaaagc caaaatatga acggcaaaat ttcttagttc gagacgatcg
     1081 tttagatcat gcggtcgcct ttttatggaa agatccacag acaaaagaga cagtaggggc
     1141 gagttatcaa ggaacgttca ttgattatga acgttttggt gagagaggca catataagca
     1201 tatagataaa aattcgacag cgaatcatgg ctttaaccta aagatcggtg accctaagca
     1261 gttaaaattt tttgagagta gtattgattt acttagctat gctgcactga atcgtgatca
     1321 gttaaacgat acgtggttag tctctatgga agggttaaaa caccatgtga tcagtcatta
     1381 ttttggtgag gcagtatctg aattgagaaa gaaacaagcc tttcctcaat ccatcgagat
     1441 ttgtgtggat aatgaccgtg caggacatat tttctacgaa aaagaacaat taatgggcgc
     1501 agtcgatcca tttacgaatc agaaagtacg ttgtgaacga ggaatcgcta atgattggca
     1561 agtgccaaaa gaatacaaaa tcatttatga agaagtcgca aaagaagaaa aggtcacacc
     1621 agaagctatt atggccatac acaagacaga aaacaatctg caattaacga accaactggt
     1681 ttccgctcac aaagtaaatg cgttttttgg ccagcagctt tctgttaacg attcaataga
     1741 agccattaat ttgaaagata tttgtagaga agtcgcaaaa gaattaaaag tttgtgaacg
     1801 cgtggatggt acgtacgatt ttgatcgttt ttatcaagaa aaaggggata ttaatgcgca
     1861 gattcttttc tcttataaag cagaacaata ctacaaaggc tataaaaatc atgaacatga
     1921 atttatacct gaagtaaaaa aggactggaa cgatcaattg aagcatgaga tccagcaaca
     1981 agaaatcaga aagcaaaaac gtgccatgtt gtttcaacaa ggcagacaac aagaaaggga
     2041 gtgaaatcgt catgatgaaa accgttattt tagcagaaaa gccgtcacaa gcgaaagctt
     2101 atgccgatag cttctctaaa gccactcgaa aagacgggta ttttgaaatc caagatcgat
     2161 tgtttcctgg tgaaactgtg atcacgtatg gttttggtca tttagtcgaa ttagattcgc
     2221 ccgatatgta cgatgaaaat tggaaacaat ggtcattaga acatttgcct attttcccta
     2281 cacattatca ctatcatgtt cctaaagata agaaaaagca attcaaggtg gtgaaacagc
     2341 aacttcaatc ggccgacacc attattattg cgacagatag cgatcgtgaa ggggaactga
     2401 tcgcttggac gatcattcaa caagtaggcg ccgatcaagg aaaaaccttt aaaagacttt
     2461 ggatcaactc cttagaaaaa gaagccattt atcagggatt ccagcagtta cgagacgcaa
     2521 aagagaccta tccaaaattt gaagaagcac aagcacgtca gatcgccgat tggttaattg
     2581 ggatgaacgg tagcccactg tatagtttac tcttgcagca aaaaggcata ccaggaagct
     2641 tttccttagg cagagtccaa accccaacgc tttacatgat ttatcaattg caggaaaaga
     2701 ttagaaattt caagaaagaa ccttattttg aaggaaaatc cgaagtaatc gctcaaaatg
     2761 gcgcatttga tgcgaagctt gatccgaatg aaacccaagc gacgcaagaa gcatttgaag
     2821 attatttaaa agaaaagggg gttcaattgg gaaaacagcc aggcatgatt cgccaagttg
     2881 aaaccgagaa aaaaagcgcg gcaagtccac gtcttttttc tctatccagc cttcagtcta
     2941 aaatgaatca gctcatgaaa gctagtgcca aagacacttt ggaagccatg caaggcttgt
     3001 atgaagggaa atatctaagc tatccacgaa cagacacccc ttatattacg gaaggggagt
     3061 atgcgtattt gttggatcat ttagatgaat acaagcattt tttaaaggcc gaatcaatcc
     3121 caacccctat tcatacgccg aatagtcggt atgtgaataa caagaaagtc caggaacatt
     3181 acgcgatcat tcctacaaaa acggttatga cagcagcggc ttttgaacaa ctaagtccac
     3241 tgcagcaggc catttatgaa caagtgttaa aaacaacggt ggccatgttt gcggaaaaat
     3301 atacctatga agaaacaacg atcttgacgc aagtccagca gcttcagtta aaggcaatcg
     3361 gaaaagtacc gatagatcta ggttggaaga agttatttgg caaagagaac gacggaaaag
     3421 agaaggaaga agagccgcta cttcctaaag tgacaaaagg agaaatggtg acggtagatc
     3481 tacaagtcct tgaaaaagaa accaagccac cacagcctta taccgaaggt acgttgatca
     3541 cggcgatgaa aacagctggg aaaaccgttg atagtgaaga agcgcaatcc atattgaaag
     3601 aagtggaagg aatcggtaca gaagcgacac gggcgaatat tattgaaacc ttgaaacaaa
     3661 aggaatatat caaggtagag aaaaataagc tcgtggtgac gaataaaggg attttgcttt
     3721 gccaagccgt ggaaaaagag ccgctgctta cgagtgccga aatgaccgcc aaatgggaaa
     3781 gctacttgtt aaagatcggt gaacgaaaag gaacacaaac cacttttcta gccaatatcc
     3841 aaaaatttgt ctctcactta ttggaagtcg taccagggca aatccaatcc actgattttg
     3901 gatcgacgtt acaagaagtg aaagcagcca gtgaaaagca agaagccgcg cgtcatttag
     3961 gaatttgtcc aaaatgccag gaacaagaag tcttactcta tcaaaaggtg gcagcatgta
     4021 cgtctgaagc ctgtgatttc aaactatgga caacgattgc caaaaagaaa cttacagcga
     4081 cacagctgaa agagatcatt caaaatagcc gaacaagcca accagtgaaa gggttaaaag
     4141 gtcagaaggg ttcgtttgaa gcaacgattg ttttaaaaga agacttcact acaggctttg
     4201 aattttctga aaagaaaaaa acgaacttca agaaaagaac acgacgcact acaaaataat
     4261 ggagggttaa tcttatgcgt aatacaacac acaaacaaca agaaatcgaa aatcaaaaag
     4321 ccaaaattcg ttcagaacag gaaaaaatgc gtgccagcaa acgaagactg cagcaattga
     4381 agaaccagca gcggattcaa aaagaaatcg aattagatcg ataaattcct ttcttgttaa
     4441 tataaaacta acatgttata gttgtgttag ttttatatta actttagggg aagagtaatg
     4501 aaagacaaaa tccaatgtat ttttgataaa cataatggca acctatcctt gaaggatgct
     4561 agaagtgaag gattatcgcc tatgacgtta gatcgattag ccgaaaagga taaaatagaa
     4621 aaggtagcac caggtttcta taccttaaag gatgcgttcg tggatgaatt gtatctcgct
     4681 cagagtatct attccagagg gattttttct catgagactg cgctcgatct ttttcaagta
     4741 ggaacatata tccctaaaaa gatcaatatg atgtttccta aaggatacaa tgtatcaaag
     4801 gagaaattag atcagtatgc cattcaaccg cattacacta ataaagaaaa ttttgacctg
     4861 ggagtcacag aaacagaaag cttttacggc aataaaattt tagtctatga tttagagcga
     4921 acgttatgtg acatgtggaa tccaagatac aaagcaagcg tagaggtaaa acaagaagca
     4981 ttaaaagaat atatgacaag taccagtaga aatacaaata agctaagaag atacatggat
     5041 attttaaaat caccaaaaga aatgactttg tatatgttgc cactttattg agaggagtaa
     5101 agatgaatga caccgacaca atttaaagag aaaacaagaa atttcgcagc agagaaacat
     5161 ttaaacccac aaattgtcca aagatattat atgatggaaa aattattaga atgtattgtt
     5221 gaatcgcctt atcatgatga ttttgtatta aaagggggat ttctgattgg atcaaaatac
     5281 gggttagaaa accgttcaac cgttgatatt gatacgactt atcgaaattc gaaactaaca
     5341 aaagaaaagt tagaaactgt tttttctgaa ttaacagcta atcctacaaa agatggaatt
     5401 cgttttgaat taaagggatt aacagagacg agggaagccg attattatcc aggttttcaa
     5461 gcaaagttta ttgcttatct tgaaaatgca cgtgtacctt ttaaattaga tattacttca
     5521 ggtgattcta ttattccagc agcattgatg tatgaacaca aattaatgtt tgaagataaa
     5581 acgattcata ttccagctta tcctacggaa caaattctag ctgaaaaatt acatgccacg
     5641 tttagttttg gaaaagataa ttcgcgcatg aaagattttt atgacctgta tatgattccg
     5701 aaattagaac gtatcgatga gaaaaatttg tataagagtg ttcaaggaac attcaaggaa
     5761 agaaataatc aatcggtgtt taagcatttg tatgatcagg aaatgcctca attggtgaaa
     5821 gatgagggct tgagagaaaa gtggaaaaga taccaacaag aaaactattt tgccaaagac
     5881 atttctttcg aatctacact aacttccgtt gattccctga tgcaatcaat tgtagagcaa
     5941 gagaaggcag aacgaaaaca aaattttaag agatcacaac aaatgaatca agaaatggag
     6001 agataaagat gatcaataat gtaactttag tagggcgatt aactaaagat ccagatttac
     6061 gttataccgc aagtggcaca gcagtggcga ctttttccct agccgttaat cgtaatttca
     6121 cgaatcaaaa cggcaatcga gaagctgatt ttatcaattg cgtgatttgg cgcaaaccag
     6181 cagaaacgat ggcgacatta gctaaaaaag gcagcttgat cggcgttgtc ggacgaattc
     6241 aaacacggac ttatgacaac cagcaaggac aacgtgtgta tgtgacagaa gttgtggccg
     6301 ataacttcca actattagaa agtaaagcag cgacagaaag ccgtatgcac gctgatcaat
     6361 cgtccagcag tccaagccct accacctttg aacaacggga tacagcgacg cctaacaaca
     6421 atggattgaa cgcttcacag aatccatttg gtggacaatc aatcgatatt agcgatgatg
     6481 atctaccgtt ctaagtagca ttttctattg gttgcatttg ctacggttta tgttataatt
     6541 tagacaacaa aaagaatttt caatctataa ccaaaaacca ctagctggcg ggctagtggc
     6601 tttcttttac gtttctatta taagaattaa cgggtaggct tactgtcttt cttggcaaat
     6661 ttacaatcaa gccatttgca gatatagtgc gcggctactt ctgccatgat tgcaaaaaca
     6721 aaatcaaaaa gaattttcaa acctataacc tcctcccctt gccagattag gccggggtag
     6781 cagacagcaa gactattata gcataattga aatatccaaa tgattggatt tttgctataa
     6841 ttttagcgag gtgattgtga tgaacaaata tgttggtttg cttgataaaa tccgagtaat
     6901 aaaaacgcaa ccgttattgg ttcgctttac tttacaaacg attcatgaat cgattaattg
     6961 tgtagttgca gatattgaaa ttatcgataa attgctaatt atggatgatg gaaaatacaa
     7021 tattgccgtc acaggtcact tcaataaacg aaatcagcta gttattgcta gcatgtatgt
     7081 tagaaatccc gatcatttta cgcgatcgat gggcatataa ataaaagaag agttgtagtc
     7141 ctaaatgagg attgcagctc tttttgtttt acatagaaac aggaaaagac ctttttagga
     7201 agacacaagt gccttctcaa ttgaaaaacc tttctctcac tccaaccgcc accgccgttc
     7261 gagaagaaag gaagtgaacg ctgcacgttc actaagatat ggtgtcttgc aaagcaagac
     7321 aaaatagaca aaacttcctc tcaccaaaag gttcgttcct gttcgttatc tctttattga
     7381 tttgccagac cggcaacaag ttgcctttta tcaccaaaaa gcgacaagga caagggtaaa
     7441 tggcacgctg cgcgcccttg tccttgtcgc ttttcgttga tttattctgg ccaacaaatc
     7501 aataaagaaa gaactaacga aaggaagtaa aacctttcct aagaggaggc agaatcaaac
     7561 atgcgaaaga aatttgatta ttggggtgtt cccttcagcg aattattccc aaactatcat
     7621 gcaccacata ctgttgaatg cgattgtgga gaaagagcga aatgtatcaa aagctatcgt
     7681 ttgtatcaat gtccaacatg cgggaaaaaa tataccttgt cttatggcga ttacattttg
     7741 attgatgaga aaggaaagaa acgctgatga aaacacaaca caaattattg actgtaaaag
     7801 aagtcgttca aattttggtg gacaaagaag tcatttctga aaaagtagca gaagctttac
     7861 ttattccgcg gtactggacg atagaaaccc ctttagtaga ggatgcaccg actatgctat
     7921 ttgaagacct agtgaagatt gcaggatatg aactgcatta tcaagaaaac atggaaactt
     7981 atgaaatcga atattggtta accaaattag agaactaaaa aggagaaaaa atatggctca
     8041 aaattactat gacgaatttg tcaaattacc tttggataaa atggcacaaa aaatggagga
     8101 tatgacgttc ctataccatg aaacacgtgt acccaaaaaa cattacaagg aaaaattgtc
     8161 agtcgcagtg gaagaaatga ttgaatcagg tgtcgaaatg aatctcattg cgacgtacta
     8221 tcgaacactg gaagaactga aaaaacaaaa tggaaaatgg tttttccaag ccttactatg
     8281 cttggaagta ggtgtcaaac caagcactat caaaccttcc gaatatcaag ccttagaact
     8341 gacttatgca aaattcgcac agattaagaa agctaaagca atggctagcg actggctaga
     8401 tacttttgaa agtatcgaaa aaaatggtgc attttatacg attgaatcgg aggagaaaga
     8461 taatgaataa ggtggtttat cagctaacaa cagaagatgt ttcgcaattt ttaacaagca
     8521 aagaacactt gaatgaagta atcagacgga ttcaaaaaga ctttagttgt atggaagaaa
     8581 tgaagtactt tattcaaaga gtggaagaac agttgtatat ggaaagcgaa acaagtcaaa
     8641 cgaaggtcac agtcagccat aatcatttag acgtgtataa acgtcgtcct gaaacggtaa
     8701 aaaaaggaac agagcttcta cgactagaaa cagaaaaata catcatgaat gtgtacctag
     8761 aaaggagtga gctggtcgaa aactttgtca gctacacgat ttgtaggaaa cactattact
     8821 cagaatcaga atattattca attttcgaga gcatggaatt aatggaagaa gaaatggaag
     8881 agctaaacag caaaaatgcg acggtagacg attattacct tgtatttact aggtttttga
     8941 cgtgtgggac ggaatctatc gtgttaatgg gaatggatta tgaactcgct gtacccgaag
     9001 catttttgag ggaatatgta gaagaagtag ataacccagg cgacgactgg tacacgactt
     9061 taactgattt tttagacacc tacacttacg acgatacaga agaaatccaa aatgaacttg
     9121 accgtaaacg aatgccatat caacgatttg aaaggaaaaa aggtaaataa ccatttatac
     9181 cgaaaagtga ggatgtgtga aataagaaca aaaaaccttg aaattaaggg aatggttctt
     9241 atttcgcacc aatcgctcca accgcccccg ccgcttaggt ggtgcgaaat aagcgggcaa
     9301 agcccgataa cctaagagaa agaaggagat ccatatgaat aaaatcattc ctctattgtt
     9361 cgtactgttt gttggcgaga tacttatgcg tcatgctgca gctgtacatt taaacttcgt
     9421 agtattctta ggaatactgg tattttgttt gatcttttgg cgatttgtat tagcccttgt
     9481 gagtctacta ttcaagatga ttgcagccat atttttcata gggttatttc gatgaaagga
     9541 gagagtacta atgccaattg caataggaaa taaacggtta cccgtgacat tagatgaaaa
     9601 gagacaaaaa gaattgcagc aactaaagca gaagtacgga aaaagtgaat ctaagattat
     9661 gtgtattgcg ttagatctat tgatcgcgca agaaaaagca ggatttgata taccagcact
     9721 aaaaaagtga cgtcactttt catttgaaga aacaaaagtg atagcactta attgttccta
     9781 ctatttagaa tattttctat gtccttttta ttccattttg tatcaataac tatgaaatct
     9841 ttaaagtatc cagaagagat tatttttaga tcaatttttt tcttacctga ttctaaagat
     9901 tttgttttct taaacatatt atgatttcct ttcgactatt ttcatataaa tgttaacata
     9961 gtttatggat tcatggaatg ttaatctaa
//
LOCUS       DACDAF010000097         9838 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.100, whole genome shotgun sequence.
ACCESSION   DACDAF010000097 DACDAF010000000
VERSION     DACDAF010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9838)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9838)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9838
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.100"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(78..2198)
                     /locus_tag="IVZ69_002340"
     CDS             complement(78..2198)
                     /locus_tag="IVZ69_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HAP8184375.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLAKGKNVIYIHLESFQQFLIDYKLTDENG
                     LQLEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYTSAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHKG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2428..3606
                     /locus_tag="IVZ69_002341"
     CDS             2428..3606
                     /locus_tag="IVZ69_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HAP8184376.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIVGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3622..4380
                     /gene="aroD"
                     /locus_tag="IVZ69_002342"
     CDS             3622..4380
                     /gene="aroD"
                     /locus_tag="IVZ69_002342"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HAP8184377.1"
                     /translation="MVWVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLAGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4403..4888
                     /gene="ybaK"
                     /locus_tag="IVZ69_002343"
     CDS             4403..4888
                     /gene="ybaK"
                     /locus_tag="IVZ69_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HAP8184378.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSHIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4959..6212)
                     /locus_tag="IVZ69_002344"
     CDS             complement(4959..6212)
                     /locus_tag="IVZ69_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HAP8184379.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6328..7677
                     /gene="gdhA"
                     /locus_tag="IVZ69_002345"
     CDS             6328..7677
                     /gene="gdhA"
                     /locus_tag="IVZ69_002345"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HAP8184380.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNAQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7789..9135
                     /locus_tag="IVZ69_002346"
     CDS             7789..9135
                     /locus_tag="IVZ69_002346"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HAP8184381.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9443..9829)
                     /locus_tag="IVZ69_002347"
     CDS             complement(9443..9829)
                     /locus_tag="IVZ69_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP8184382.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYTEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3141 a         1790 c         2012 g         2895 t
ORIGIN      
        1 tattctaaga tttctcttta ccaacatcat ttgacaaaga gcctaatttt gtcgctgctc
       61 cttttaaatt tattttatca ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac
      121 gtttgcgttt tataaagatc aacagttgat tgtcccttgt gttcactaaa gacactagtt
      181 gacttgtcac caagagattt ttcagcttct tttaatttct ctaagccatt cttgtagtca
      241 taatcactgg tatcaattgg gtctaatcca ctattcgtat agaaccgaag aagatcacca
      301 ttattgattt ggtcagaaac agctaactgt ttatcaactt tttctttcag tgaatcaatt
      361 tcattctgta cttcctcagt aggttcagta atagcttcac cagtttcgtt actatagatc
      421 gtaccaccgt agtaagtata ttttggtgta acaaaatcac catcacggaa agaaacaagc
      481 tgttcatgat ctttcgagaa tagatcttgt cctaactgaa tataattttt tgtatctaca
      541 cctagtaagt gaagtaatgt aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt
      601 ccgccctgtg tttgtccagg gatatggatc atataaggga cacgctgcat ttgtgcattg
      661 tcgtagtttg tccaagtaga acttgttttt ccaactaatt cagctagatt tttatttctt
      721 gaattcgaga caccgtaatg gtcaccgtaa aggacgatga ctgaattatc atacaagccg
      781 ctttctttca aataattgaa gaattcttgt acggcggtat ctaaataatt ggctgtcgca
      841 aagtaaccgt tgatcgtttc atcatttgta ttggctaacg ggaatcctgc ttcgtcattg
      901 gtgaattttg aataaggata atggttagat acagcaatga attttgaata aaatggttgt
      961 tgcagacgtt ccaagtattg tacggattgt tggaaaaatg gtttatcatg caacccgtat
     1021 tggaacgaat tgtcatcatt aacatcataa taagaagaat caaagaaata atcatatcct
     1081 aaattcttgt atgtctcgtt tcgattccag aatgtaccag cgttcccatg gaataccgca
     1141 ctagtgtaac cttgtgtttg acttaaaata tcaggtgcag cttggaaagt attttttccg
     1201 cctaattgtg tgaacaagga gccttgattc aagccaaaca atgaattttc catcagcgtt
     1261 tccgcatcgc ttgtttttcc tgcttttact tgatggaaaa agttgtcaaa actgaacgtg
     1321 ctgttgctgt ggtaaagact attgatgaaa ggtgtaactt caagctggag accattctca
     1381 tctgtcaatt tataatcgat caggaattgc tggaagcttt ctaaatggat ataaatcaca
     1441 ttttttcctt tagcgagccc gaacaaatca tcatttggtg ctgcataatg ttcttttaca
     1501 taattttcta cttctttcat atcattggga cttgcttctg cccgcacttg gtttgtctgg
     1561 taagtttgaa caccgtcata aaccatgaaa gcattcaagc caagatattt gaccaaataa
     1621 tcacgagaga atgttcgagt cagcaattct ggacgatcag cttccgccat aaaaagattt
     1681 cctgagaaaa tcataactgc taatgtagag atcgcaaaag ccattcttgc tcggatcggg
     1741 cgagggtcca acttgatttt ttttgcaatc agcagaacag tcaagataat aaaatcgatc
     1801 caatagatca catcatatgg gcgaaacagt cgaatggcac tttctcccag accactcgct
     1861 actttcccag cacctaaaat cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa
     1921 gtgacattcg aaaaaacaag caatgtcaaa agaaaataaa tgaccatcat cgtgatataa
     1981 gcaactctag ggcgtctgat ataaagagca attccaagta ataacaatgt agttgcaata
     2041 gggttgataa acaagataaa gtattgaatg ccactttcga ttccgagatg gaaatcaact
     2101 aaataggcaa aaatcgtttt caaccaaagt aaaacaacta gtaaagaaaa aaatccgagc
     2161 ctcttattca aaaaggcagg tgtttttata catttcaaga taatcttcct ttctgcactt
     2221 cttaatcaca gaagtgtcat gaaaccatgt tacacagctc acttattctc atttatttta
     2281 ctagtatgac aatatagtgt caattgaaac cagaagttta tgctgtttca ttaaggtttt
     2341 ctttaagctt catgaaaaaa tgagcagtaa gacaagtcct atgttttttg ttatacttgg
     2401 gaagagaaag ctaaagcagg tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat
     2461 cgattgaaaa aaggatatcc actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa
     2521 accacgcaat gggtggaatt agttgattcg caaaaccaat ttatcgcaaa aggatatcta
     2581 ggaaagcaga ataagggaat cggttgggta ttgagccagc agaacatccc atttgatcaa
     2641 tctttttttg aagaattttt tgtgaagtca aaagaaaaaa gaactttctt tttttcagat
     2701 gattctacta ccgcttttcg tatattcaat ggagaaggag acgggatcgg cggtctgatt
     2761 gttgattatt atgcaggtta tgctgttttt tcttggtata acgaaacgtt atatgcacat
     2821 cgtgaattat tgattcaagc ttttcgtgaa atctacccgg aaatcgtagg aggctatgag
     2881 aaaattcgat ttgaatcagt aaatctgcct gagagccagt tcatttacgg aaaagaggca
     2941 ccggaaccct tgatcgtaaa agaaaacgga gtaaaatttg ccgtttattt aaatgaagga
     3001 ttaatgactg ggatcttttt agaccaaaaa gaagtacggg gatcattagc agaaggtttc
     3061 gcttctggga aaacagtttt gaacatgttt agttataccg gcgccttttc tgttgctgcc
     3121 gcaatgggag gggcaatcga aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa
     3181 acacaggaac agtttgaagt gaatggtttg gatgtcgatc agcaaaaaat cattgttatg
     3241 gacgtattcg agtatttcaa atacgccaaa agaaaacaat ttttatatga catgattgta
     3301 ttggatccac caagttttgc cagaaataag aaaaaagtct ttcgcgtagc aaaagattat
     3361 ggggaactgg tcaaggatag tctggatatt ttagcagaag acgggatact tattgcgtct
     3421 acaaatgctg cgaatgtctc gatagaacaa ttccaaacaa tgattgaaga ggaattccat
     3481 gccaaaaatg tttcttttga acaacttgct ttatatcgtc tgccaaaaga tttccagacg
     3541 acggatacct ttttagaagg caattatctg aaagtgtttg tttatcaaat taaaaataac
     3601 cattagaagg agcgatgcag aatggtttgg gtaaagggat tgaatatagg aagcggtaga
     3661 ccaaagattt gtgcgcctct tatcggggcc gtccgagagg aagtattacg tgaagcagtt
     3721 cttgcacgtg aagcaggggc cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt
     3781 ttttcttttg atgaagtagc agaaacattg gttcttatcc atgagatgct tgatggactg
     3841 ccgttattat ttacgtttcg taccttagct gaaggcggag aacaagacat atcgatccgt
     3901 cagtatcgcg acctttatga acatgtgata cacacaggat tagtagatat ggtcgatatc
     3961 gagttgttca aagtagaaag tctaggaaaa agactgatag aggaaatcaa gtctttaaac
     4021 attcctttaa ttatcagtag tcatgatttt aaagaaacac cagcagaccc tgtcttgctt
     4081 taccgattga atgttatgga acattttgga gccgatatcg gaaaactggc agtaactccc
     4141 aataatgaac gagatgtttt gcggttgatg gagttgacta gacgggcaaa tgcttttgtc
     4201 tccatgccta ttattacgat gtccatggga aatcttggta aaatttctcg tctggctggc
     4261 ggaacgacgg gttccgttat gacatttggt tccttaagca gcgattctac ttctgctcca
     4321 ggacaattac cggtcaaagc attgaagcaa attattcaat tattaaatga accgttgtag
     4381 aacaagtttg aggtgatatt ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg
     4441 tatggtcgaa caaaaaaaga ttccctatac agagcacgaa tatgagtggg acgaaagcca
     4501 cctaagtgcg tcatcggtcg ctgaacagct tccagaaagc caatctcata tatttaaaac
     4561 actggttgct gtgggcaatg tgacggggcc tcttgttgct gtgataccgg gagaagccga
     4621 attgaatcta aaaaaattag caaaagtttc agggaataaa aaagtagaaa tgctccattt
     4681 aaaagatttg gaagcaacga ccggatacat acgtggtggc tgctcgccta taggtatgaa
     4741 aaaactattt cctacttatt tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc
     4801 ggctggcaga agagggctac agatggagtt agcacctcaa gatatctgtg cattaacgag
     4861 cggacaattt gcagatataa aacaataaat catacgtata aaagaaagaa ggaggccggg
     4921 atgttgtttg tccagtctcc ttctttcttt tttatacatt atgctctttg cccggcattc
     4981 attcctgcta catgccctgt agcgaaagcc gctgtgatat taaagccgcc agtataacca
     5041 ttgacatcca gtaattctcc cgcaaaatac agaccatcaa tgattttact ctccaatgtt
     5101 ttaggataaa tttcctttag agaaacccct ccgccagtta caaatgattt ctcaatagga
     5161 aaagttttgt tgattgatag cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt
     5221 ttttgagagg cttgttgtcc tgtcagatga tccatttcaa gccgctcaag aaagaaaact
     5281 aacaatcgct caggcaatat accatgccaa gcattgacca agttcttttt ggttgcttta
     5341 cttttttctg tcaatatatg aataagctct tgtttggttt gtgtagggaa acaatccaga
     5401 gaaagtgtca ctggttctcc cgttttctct aattctttat tgacaaaact tgaacaacgc
     5461 agtgcagccg gaccagaaat accgaaatgg gtgaaaagta aatccatcgt atgttcagtc
     5521 aatacacgac cttttttatt taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga
     5581 agtgttttct cctgaatata cggttcatcc gatatcaagg gggactctgt cgcataaaga
     5641 ggcgtcaccg tgtgacccac tcgcttcacg atcttgtacc catctccagt agaaccagta
     5701 gatggataag tccgtccacc agttgttaag ataatggcag gagcatggaa ctcttcgaat
     5761 tccgtgcgta taccgtaaat tttatgttct ttgtggatca atttctctac tcgagtagag
     5821 aatagaagcg tcacatctag ttctttcaga cgattgagca atgcttcgat aatcgttttt
     5881 gatttatttg ttacaggaaa catccgtcca tgatcctctt cttttaaatg tacgccttgt
     5941 gattcaaaga agttcatgat atcgaaatta ttccattgcg caaacgtact atataaaaac
     6001 tttccatttc caggaatatg tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg
     6061 caccgaccac cacctgtcat cagtagtttt tttcctgctt ttttgttttt ttcgatcaag
     6121 agtacgcgtg cgccttgttc agctgcactg atcgctgcca tcatcccgct tgttccagcg
     6181 ccgactacga tcacatcata cagtttttcc attccctcac ctcaaggaaa gtgtagcata
     6241 tctgaagaaa gaaaacagaa aaaatgtttt gagccaaaag agaaaatgag ctaaaatgag
     6301 ggaagataag caaaggagcg tggaacgatg acaaacgcaa cagaatatgt tcaagcaatt
     6361 caagaaaagc tacatcaaaa ggatcaaggg caagaagaat ttttacaagc aatcgatgaa
     6421 ttcatgccca cggttatgtc ttttttggac actcatcccg aatatatcga aaagaatatc
     6481 ttagaacttt taacggaacc agaaagagtt attcaatttc gagtgccttg gcaagatgat
     6541 gaaggaaact ggcgagtaaa tagagggtac cgtatccaat acaactcagc tatcggccct
     6601 tataaaggtg gattgcgctt ccatcctagt gtcaatctaa gtatcttgaa atttttggct
     6661 tttgaacaga ttttcaagaa tagtttaacc ggtctgccaa tcggtggagg aaaaggcgga
     6721 agtgacttcg atcctaaagg aaaatctgat aatgagatca tgcgtttttg tcaaagtttc
     6781 atgctggaat tgtcaaaaca tatcggccca tcgattgatg ttcctgcggg agatatcggt
     6841 gtaggagcta gagaaatcgg ctatttgttc ggcgaatata aacgattgaa aaaatatgat
     6901 actggtgtgt tgacaggtaa acctttggat ttttggggaa gtaagatacg tacggaagct
     6961 actggttatg gattagtgta ttatgtcaaa catctattga acgaagaaaa agattcattt
     7021 aatcaaaaaa cagtttttgt ttccggaagc gggaatgtag ccatttatgc aatcgaaaaa
     7081 gtgcaagagc taggcgggaa agttgttaca tgttcagatt ctagcgggta catctatgat
     7141 ccagaaggaa tagatgtgaa actattgaaa gaagtcaaag aaatcaatag acaacgtttg
     7201 acggaatacg caaaccaacg tccttctgct atttatcatg ctggagaatc tgtttggaca
     7261 ttgaaagaaa aagcggatat cgctttgcca tgtgctactc aaaatgaaat agacgaaagc
     7321 ttggccgaaa tcttagtaga aaatgggatc aaaatcgtag cagaaggcgc taatatgcca
     7381 tgtacagtaa aagctgtttc tgttcttcat gaagcaggcg tgtggtattg tccaggaaaa
     7441 gctgctaatg ctggaggagt agcagtatct gctttagaaa tgagtcagaa cgcccagcga
     7501 ttgacttggg aaagagagca agtggatgag cagctggatc aaatcatgga aacgatttac
     7561 catacgtgtc gccaaacagc agccgagtac ggcgacgaaa aaaatctgct tcttggagca
     7621 aatgttgctg gatttgaaaa agttgccaaa gcaatggcag cagaaggttt agtttgaaaa
     7681 atgaaacttt cttggaaata ttgtcagcat tttgtttatt tgcttgaaaa ataataaaaa
     7741 aaaacgtaaa gtattacctg tagagtaaac ctataaggag gagaacaaat ggcacacatt
     7801 cattttgact attcaaaagt agcaccgttt gtcaacgaac aagagttagg gtacatgcaa
     7861 agccaagtaa cagcagccca caacgaatta cgggaaggta ctggcgcagg aagcgacttc
     7921 cgcggctgga tcgatttacc aacgaactat gacaaagaag aatttgcacg tatcaaagaa
     7981 gcagctaaaa aaatccaatc tgattctgaa gtattagttg ttatcggtat cggtggttct
     8041 tatttaggcg ctcgtgcagc gatcgacttc ttgaatcaca cattcttcaa tttattagat
     8101 agcaacacaa gaaaagcacc acaaatcttc tttgccggaa attcaatcag ctcaacatat
     8161 attgctgact tgatcgaagt aatcggtgat cgcgactttt cagtaaacgt tatttcaaaa
     8221 tctggaacaa ctactgaacc agcgattgcg ttccgtgtat tcaaagagct tcttgttaag
     8281 aaatatggac aagaagaagc aaacaaacgt atctacgcta caacagataa agcaaaaggt
     8341 gcagttaaag tagaagcaga tgcagaaggt tgggaaactt tcgtgattcc tgatgacatc
     8401 ggcggacgtt tctctgtatt aactgctgtt ggtttgttac caatcgctgt tagtggtgca
     8461 gatatcgatg cattgatgca aggtgccgct gatgcaagca aagcatactc aagcgacaaa
     8521 ctagaagaaa acgaagctta ccaatacgca gcaatgcgca acattcttta ccgtaaaggc
     8581 aaagtaactg agttgttgat caactatgaa ccaggaatgc aatacttctc agaatggtgg
     8641 aaacaattgt atggtgaatc tgaaggaaaa gaccaaaaag gcatctatcc ttcaagcgca
     8701 aacttctcaa ctgatttgca ctctttagga caattcatcc aagaaggacg tcgcaatatt
     8761 tttgaaacag ttgtgaaggt tgaaaaacct cgtaaatcaa tcacaattcc tgaacaagca
     8821 gaagatttag acggtctagg ctacttgcaa ggaaaagaag tggacttcgt aaatacaaaa
     8881 gcatttgaag gaacattgct tgctcataca gacggtgacg tgcctaactt gctagtcaaa
     8941 attccagaaa tggatgctta tacattgggt tatacaatgt acttctttga aattgctgta
     9001 ggtatttcag gttacttgaa tggaatcaac ccattcgacc aaccaggtgt agaagcttac
     9061 aagaaaaaca tgttcgcact tctaggcaaa ccgggctttg aagatcttgc taaagaattg
     9121 aacgaacgcc tgtaagataa gggtttttcg ctagatttaa ataatcagtg atagaaacat
     9181 gttcgcttta aaatgaaaac tggtacccat ttaggtactc aaacatactg catcgtttat
     9241 tcagaataag gggctgtgac aagacgtttg tcacagtccc ttgtttgtat agaaatcgat
     9301 tgattgcctt gctctttagt ttgttttagg actttaagaa cagtgaggct gacttcgaag
     9361 gttaattctg tttttttgtt ttctagaatc agtaagcaaa aaagcactca cttcgagtgc
     9421 ttttttgcga tatattctta gcttaagata ggcctaattt ttcttttaca gatgagggta
     9481 ccttatcgct ggtaattact tttttctcta tgatccgctt ttcgcttgct ttcaactgca
     9541 agatcgttcc ttcggtgtaa gcagaaccat tggcagagtc accagaagta atgacatcga
     9601 aatctaactg tcttttttca ccgttttcag cataagcatc tacgttgtat ttaaaacctc
     9661 ttccaattac ttccccatta tctgctttga tatcagtttc tgcaggcatt ggagctttga
     9721 ctaccgcata ataatcttta cctacataag tagactgata gtagtcccaa cctttccatc
     9781 ctataaaagc aatcaatatg ataacgatca accctaaaat ttttttcatg aaagatct
//
LOCUS       DACDAF010000098         9821 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.101, whole genome shotgun sequence.
ACCESSION   DACDAF010000098 DACDAF010000000
VERSION     DACDAF010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9821
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.101"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..195)
                     /locus_tag="IVZ69_002348"
     CDS             complement(<1..195)
                     /locus_tag="IVZ69_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184383.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNY"
     gene            complement(211..825)
                     /locus_tag="IVZ69_002349"
     CDS             complement(211..825)
                     /locus_tag="IVZ69_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HAP8184384.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(972..1655)
                     /locus_tag="IVZ69_002350"
     CDS             complement(972..1655)
                     /locus_tag="IVZ69_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP8184385.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(1764..2222)
                     /locus_tag="IVZ69_002351"
     CDS             complement(1764..2222)
                     /locus_tag="IVZ69_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HAP8184386.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(2306..4069)
                     /locus_tag="IVZ69_002352"
     CDS             complement(2306..4069)
                     /locus_tag="IVZ69_002352"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HAP8184387.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(4290..5750)
                     /locus_tag="IVZ69_002353"
     CDS             complement(4290..5750)
                     /locus_tag="IVZ69_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184388.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(5958..6884)
                     /gene="glsA"
                     /locus_tag="IVZ69_002354"
     CDS             complement(5958..6884)
                     /gene="glsA"
                     /locus_tag="IVZ69_002354"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HAP8184389.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(6907..8334)
                     /locus_tag="IVZ69_002355"
     CDS             complement(6907..8334)
                     /locus_tag="IVZ69_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8184390.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(8365..9579)
                     /locus_tag="IVZ69_002356"
     CDS             complement(8365..9579)
                     /locus_tag="IVZ69_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HAP8184391.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         2913 a         2041 c         1628 g         3239 t
ORIGIN      
        1 gtaattaaac aatccgctaa tcgtttgatc tggcatttct atttccttac catctaaagt
       61 aacagtagta acgacaaaat ggtcttgcaa tggcggaact tctaagtact gcccttgcag
      121 aaaatcattc actgtttcat attctttttt catttctttt gaatctgtcg atggtttata
      181 gcttattttt aacataacta gtgctccttt ttattcggga cgtgcaatcg tgaaaatttc
      241 tcctattgct gcataatcat ttcctgccaa acggcttaca gcattcaatt ttcttggatc
      301 gatccttcct gtcttatcat catagactgt ttcatttaaa tgatatttct gtacttctag
      361 caaaaataaa tcagctgtta ctttattttt attccgtatc tcgacatgtt catataagga
      421 tgtttcaaaa cgaacttttg cttctgtcaa tgctggtact gaaatgatta ctgaatcagt
      481 taaagtcaag tcagtcaggt acagttcgct ttcctcatta ggcagattgg ctgctgtttt
      541 atttacttct tctacgttgt cctcatcaag gatatggata acagcttctc ttgtctcaag
      601 aatattcttt gctgtgtctt ttactgcatc ttgttttctc tggatcgcca aggataagat
      661 gggtcgattc gaactgacga tattgaagta actgaagggt gcgatattca ctatatcttt
      721 tgctgattta gtcgttacta ctgctactgg tctagggatg actgaaccaa tcagcaactt
      781 gtaattttca cgttctgtca attctgaagg actccgttca aacatggttt cgccttcttt
      841 ctataaaatt cgttaaaaag cagatcttga agacaaaatg aaaagtaatg cttttttcat
      901 cttcttagaa tctgctttaa actatctatc aatttttctt ttttgtcaag aatctgtgcc
      961 gtgcgtgttt tttagttatt tgctttactt gcggcttcga catatctttt agtgatcaat
     1021 tgcggacggg tgataataga tccaactacg actgaaaaag cacctaattc atatgctttc
     1081 tctacttgtt caggagagtc agtatgtcct tccataatta ctgggatatc gacttgttct
     1141 atgatttgat tcaataaatc aaaatcaggt gtctgcgtct ttcgtgaata ttctgtatag
     1201 cctgctaaag tcgtagacaa aagatcaaaa ccatcttctt gcgcttgaag cgcttcctca
     1261 aaagtcgaaa tatctgccat agctaaccga ccgtgttcgt gaatcatttg gacaagttca
     1321 gcagttgttt tttctgtcgg acgtttacga gaagttgcat ccagtgcaat gatttctgct
     1381 tgcgtctcca aaagttcttc cacttctttt tctgtcgcag taataaacac ttctgaccca
     1441 tcgtaatctc ttttgataat ccctattacc ggtaaatcaa cgattcgctt gatttcattg
     1501 atatcttctg tcgtatttgc tcgaatacca actgctccgc cttcttttgc agccaaagcc
     1561 attctcccca taataaaaga actgtgtagc ggctcgtttt ccaaagcttg acaagaaacg
     1621 acgactccgc ctttgatttg ttccagtgta tccacaatat ctcctccagt aatgttatat
     1681 aaaaatacag cttcatataa aaatgtaacc cttttctatt caggagacaa taatgagcta
     1741 tttctttcag cagacctttc ttactaaaag aaaattactt caaattcttc gtatacgacc
     1801 agcttctctt ctgtaaattc tatgttcaac gcttctttat aagcatgttt aaaaaactca
     1861 gcatggactt tccgccaata agctaatgtc cgatcccctt ctccttcttt ccaagcatgc
     1921 tctttcgtga cttcactaaa aggcaagatg gtcacattta tatttttgat gatacaaact
     1981 ggttcatttt ttccattcag gaccacgtct aattgaccaa cttttggtaa aggctcattc
     2041 tcttgtttat acagatcgta accacttgat gtaccagtct ttatcttttt tacaactagt
     2101 tcgctcaact cgtctgccat tttttctgta tccccaaatg aaaagaaacc taatttttct
     2161 gattgataac taggatattt ttcttggaac tttttgacat attcttctac ttgctgatac
     2221 ataacatcca cccctttgct ttttataatg aaaaaaccat ccagatacta gtataaacaa
     2281 ttatctggat ggtgagcata atgaattatt gaatattcaa gacacgcaga ctatcttcaa
     2341 cgatttgttt tggtgttaaa tgataacgtt cataaagctg ccctacagga acgctatccg
     2401 tgaattcttt ctctgcacca aaatttaata cgttcattga agaatcacca taataacgac
     2461 tgatattttc gccaaatcct cctgacaaac taccatcttc taatgtgatg actaattcgt
     2521 gtgtttcttt taatttatct aatgtttcta cgtcattttc tgtgatcgtt cctggattga
     2581 tcaacgttgc ttcgattcct ttttttctaa aagcttttac tgtttctttt cctaattcaa
     2641 gaaaaccgcc taaagctaaa attgctactt ttcctccatt atttactgtt tgataggctg
     2701 gaatactata atcatttgcg atagctgtac catgttctac accatgtgta ggaattcgga
     2761 ttgctacagg ctgcgctgtt tgttcgaacg cccaatctag catagagatc atatcctctt
     2821 ttgttgctgg agcaagatat ttgatgttcg ggatacttga taagtaagga atgtcaaatg
     2881 ttccttggtg tgttcggtca ctagctgaga tcgttccgcc accgactaaa ataatcactg
     2941 gattctcgtt gatcgctaaa tcatgtgata attgatcata tgcccgttgc aagaaagtac
     3001 ttgattggaa gacgactgga cgtactccct gagaagccaa agcagaagcg aaagtgatag
     3061 agtgctgttc agcgatcccc acgtcaaaat aatgatctgg atgtttttct tggaatgttt
     3121 tcagtccaaa ggcgcctggt atcgctgcat tgactgcggc aataggagct gtacttgttt
     3181 gcattttctt atccaaataa tccatgatga tcatattaaa tgtttctcca gaagttactt
     3241 gctttgcctc cccggtggac agatcaaatg gtacatgcca atgatatttc attttattat
     3301 cgattgccgg ctgataaccg cgaccttttt ccgtatggac gtgaagtaca atcggatgat
     3361 caatatcttt tacttcttca aataaacgga tcaccgtttc cagatcgttt ccattatcca
     3421 cgtaacgata atcaaatccc attgctttaa ataggttatt gctgctttta ccgttggttt
     3481 gacgaagctc agctaagttt ttatataaac tgccatgatt ctcatcaata gacatctcat
     3541 tatcgtttac taatacgatt agattggatt gtaaaacacc accattgttc aatccttcaa
     3601 aagctaagcc accacttagg gagccgtcac cgataaatgc taccacattt cctgattctt
     3661 tcttcagatc tctcgcttta gctaaacctg ttgctaagct gatagatgta gatgtgtgcc
     3721 ccactgtaaa atagtcatgt ttactttcat gttggttgga atatccgctc acttcacggt
     3781 aatgtccttt ttcaaaacca ttttttcgac cagttaaaag cttatgacca taagactgat
     3841 gggaaacatc ccaaacgatt ttatcctttg gtgaatcaaa tacataatga aacgcaatcg
     3901 ttaattctac tacacctaga ttcggaccaa cgtgcccacc tacatcgctg tccttttgca
     3961 agattttttg gcgcatctct tctgccaact gtttcatttc ctcaacagat aattttttga
     4021 catctgcggg gctattgatt gcatccaata catgtaatac tgtactcata atacattctc
     4081 tcctccgtac tatcttcttt taatgaaaat agatttgtta cactttatct attctactac
     4141 ttagagttga ctctaagtca atagcatttt aaaaaaattt cagagaaagc ttgttatata
     4201 agtagatctt cgcacgaatc aggactcaaa taaaaacctt ctacagacaa ttaaaaagct
     4261 ttgtagaagg tctcctaatt aaggtctcat caagaaatat gtttttttaa taggtgaagt
     4321 tcctgagcaa tatgatacaa atggatgttt gcacctttta atgagattgg atagatcttt
     4381 gtcttttcag tttctaatcc attttgatag ctagcagcat cgcacaaaac cactcttttt
     4441 ttcgcacata gacattcatc aggcaattct tctaatgaac gaaataaaat aggatttatt
     4501 tcagcgatgc cttcttccgc atacaaatga aattgggttc gataaaaaaa ttgtttgact
     4561 gaactttctg aaacaacaaa aatttctatt tcctgtctcc ccgcttgttc actgttgatc
     4621 aaagaaagac ttttgacgaa ttttcgaatg aaattttcat tccatcttag ttggatttga
     4681 tttttctttt tccactcttc caatatttct acaatttttc cgtacagaag ttgttctttt
     4741 tctgatagaa gatagatcct ttccggtaaa aatacttgtc catctgccca caacgtacgg
     4801 acaaattgta aaaaggattg cttgaaaata aaattttctg catcgtcgat ttcagcgata
     4861 ctaataatct gtaaaatcaa ttcattcagt gataggtcat tgagaacaaa atttttataa
     4921 acaacttcga aatcttttct taacagctcc atgttctcat tggtataatt tctactgttg
     4981 aacaaagaaa aaatataata gacatcttct tcttgtaagt ctagaattcc tttttgctct
     5041 tccaatcctt gacagactaa ttgaaataac ggcttcgttt ctgcgctttt cttatcttct
     5101 tctttcagtc caaggggaaa tgcctttctt ccgattgcga tctctattcc tcgtatgata
     5161 aaggactttt catcttccga atatcttctt ttaaaaaaat gagtctctac ataatcaatc
     5221 aactcgttac aagcttcttc tacatacgga tttttatttt catagccttc ccaattgaca
     5281 taacgtacta aagctagcaa gatgttccgc gagtcaaatt ctgggataat gatttcttta
     5341 tttttcaaat aatcattttc tttaaaaaaa tccaatacga tttttttgat tgtatatact
     5401 ttgctcaaag aaataaattc aagatcagcc agttctgtac tcgtgaatat accattaaaa
     5461 taataactta aaaactttaa aaaataagat tgaccgtaca gaaactgtgt gagctcagaa
     5521 agagcaatac catgtttgaa tacgagttta tacttatgct tctctcttac ttgttctttt
     5581 atacaatatt ctagacactc ggctagactt tctagatcgt gaaggatcgt tggtgtagtc
     5641 acccttagag aaatagctgt ttgttcgatg tctatttctt ggaattcaaa taattgttca
     5701 cacagataca cttttctaaa tatatttcgc tcgatgtaat tttccagcat tcctgataca
     5761 cgcctccagt ttttcttatg attttattta atcatatctg taaatcgtat ttttgtttcc
     5821 tttttattta gaaaagccct ttcaaaaacc aataaaaaaa gaaactggga caaaagtcaa
     5881 acaagctcac aatttcagcc tcattgtagg tagctttgag ccgtttggac ttttacccca
     5941 gcctctttca agaatggtta ttcaaagatg tcagcgtcta gttctttgac tacatctttc
     6001 aacaattgga taccagctgc gctgttacca aatggatcta gtgccgggct gaagacacct
     6061 atgccgtaac gatttggcac agctgccatc aacccgccgc ctacaccgct ttttgcaggt
     6121 acaccaacat ggacggaaaa ctctcctgat tcatcataca aaccagcagt tgtcataatt
     6181 gatttgacga ttgtagcact ttcttcagta atgatttgtt tgccattcca aggagcaatt
     6241 cctttatttg ccagcacagc agctaatttt gctatgcctg tagcggtgac attgagggag
     6301 cattgtctga aataagcatc gagtatctcc ggtacgtctc cttcgatcat ttgattacct
     6361 ttcatatagt aagcaagaga gcgattgata tcacctgttc ttgattcaga atgatagatt
     6421 tcttcattca atgtgatatt aggatcatca cagatctctt tcataaatga caagattcgc
     6481 tcaaattttt catctgcatc tttaccggca atcaacgagg ttgttgcaat cgctcctgca
     6541 ttaacaaaag gattcattgg atgtttgcga tgattgattt ccatattcat gatagaattg
     6601 aaggcaaaac cggttggttc cgtgttgatt gtttgaaaga ctttttctat tccgttgtct
     6661 ttgattgcta ataacaatac gggaactttt gacatgcttt cgatggcaaa gcgcacatcg
     6721 gcgtctcctc cctcaatcag ttgttttgta tccaaatcat aaatcgccat acctaattgt
     6781 ttgggatcca cttcagctaa tgctggaatg taatccgcca cttgtcctgt ttgataatag
     6841 tggaaatttt ttccaatcaa ttgttctaat tcttttactt ccatttgaat aaccagcttt
     6901 cattttttat ttttctgcat gctggaattt atgacggcat gcgtagatcg taaatggaat
     6961 aactaagacg ataagataag aaacaatcag aatcgtttca taaatcccat gctgtccagc
     7021 tgcgatacta gcaggtggaa caaatgagat acaaaaagca aaaagtgaag tcaaaagacc
     7081 taaacaagca acgattactt ttacaacttt tccgcctgga acctgatagg ctctttcaag
     7141 actgtcatct ttaaaaacca gcttcaaata gcccgcgaaa aacataaagt acaacatcag
     7201 gtagattaca acagtcaatg acatcgctgc aagaaatgaa agattattcc ccccgccgct
     7261 taatgtaaag acggctgccc agattgttgc aacgatccca tttgcgatca tcaaatgagc
     7321 aggaacaccg tgtgtgtttt cttttgcaaa atattcagga agtaatcctt cttctgctgc
     7381 tacgtgaagt gcttttgaag gagaggttac ccaagaagca atttctccga tgacacctaa
     7441 acaaacaaga atcgcaagaa ttttcgcaat ccatgcaaga tttggatcaa tgtgtcttaa
     7501 taggaattct aacgattgaa tcacccctgt attaagagac aaaccatgtt gaggtactgt
     7561 agtagcgacg gtcaatccgc caaaagtatc taaaatgatt gccagaataa ccaatacaaa
     7621 cattgctaat ggataatcct ttttagggtt ttccatttca tttgcatgac tggcagatgt
     7681 ttctacgccc atatatgcta aaataaagga aacaaaaaca accagcgtag gcaatttcga
     7741 aaaatcagga atcaatgttt tcatagacag tatcgtttgt agtggagcgc ctgaagcgac
     7801 ataatggatc cctaagccaa acaagactaa tgctggcaac aagataccag ctacaaaacc
     7861 gatccgagca atcaatgaag tgtatttggt tccttttaac tgtgagagta aaatagccca
     7921 gaaaataatc aataggattg ccaatttcag atatttattg ttttgtatag caccaatacc
     7981 cgttgcatag gataatgcac cagttaagaa atacagcatg gtcaagtagc caactgttat
     8041 ctcaaaccat tggaaaaaga ttgcggcaaa accgaatcgt tttcccaatg tgcgactgac
     8101 ccaagtatag acaccgcctt tttcccatcc tttcaccgtt gccatctctg ctgcgcacaa
     8161 tgccacaggg ataaaccata gcaaaccgcc taataacaag aaaaatacta agctgaagcc
     8221 tgaggtcgcg aatgtgggat attcatataa tgaaacgacc attgagatgg tcatagccaa
     8281 aaagccaaag aacgttaatt tttttgcagg aattttcgtt ttgctttgtt gcatgaatct
     8341 tcctcttttc tatttgaatt tgtttcaatt gagtttgttg ccaaagaaga aaaagtccaa
     8401 tccttcttct tgttcttctt ttgtagtagt gatcgttgta aagtgcatcg ccgattttaa
     8461 aatcactgtt gtcagcacat aggcatacac ggcagtaatg atgacaccaa tcacttgaat
     8521 ccctaagaag taccagctgc ttggattcgt tagtaaatgg ctgttagatg caaagatccc
     8581 tatcagaatc gtacctgtga atccgcccat gccatgaaca ccccacacat caagtgcatc
     8641 atcccattgt ttctttttac gaaaatcaac agcagcatga cagacgatac ccgcaatgat
     8701 cccaatcagc atggcacttt ttgcttctac ataaccggca caaggcgtaa tggctgccaa
     8761 tccagcaacg gatcctgtta gtacgtcgac aaaatcaaag ccatttcctt ttacttttgc
     8821 aatgatcagc caagtaatca tcgcaaatgc aagagcgatg aatgttgaac caaatgcatt
     8881 gactgcttgt tcatctgctc gaagtgcacc accggaatta aaaccgaacc agccaaacca
     8941 aagcagtcct gtaccgatag cagctgccat aagactgcta tgctgacttc tttctcctaa
     9001 aggaatcttt ctttgaccaa gtgtgaggat acatgctaaa gagccgaatc cagctgtcgt
     9061 gtggatgact gctccaccag cgaaatctct aaatcccatc tgatccaaaa atccgccacc
     9121 ccatatccag tggcaaacag ggaaataaat cagcagattc caaaaaataa caagtataat
     9181 atagcctttt aaattcaatc tccctgcaaa agctcctgtc atcaaaggaa cggtaatcac
     9241 gataaacatc agttggtaaa gaaagaacat taaaaatgga atcgttgcac catgaaacat
     9301 gttggggaag cttgtaacat gtctcatcaa aaagaaatct gccgggtttc caataacacc
     9361 gccgatatcc cgtccaaagg ccaatccgaa tccaccaaat acccacataa tcgttgttat
     9421 cccaacggag agaaaagatt gagacatgat cgttagtata ttattcttcc gtgctaatcc
     9481 gccgtaaaaa aaagctagac caggagtcat caggcaaacc attgctgtac ataaaatcat
     9541 gaatgctgta tctcctgtat tgataggtaa tgtattcatt tttttcgcct cctttctacg
     9601 attacgagta taaaagaagg tgtagttgtt tttttcttct gtttttttga attaatactt
     9661 gcatttataa aagacagaca attaataaaa gcttgatgtg ttgtgctctt tttcgttttt
     9721 cacacaaata aagacaaaaa ataaacggtc ttctttttat agaaaaccgt ttattttcgt
     9781 ctttttttat ttttaaagat attttttcat aaggaataaa g
//
LOCUS       DACDAF010000099         9572 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.102, whole genome shotgun sequence.
ACCESSION   DACDAF010000099 DACDAF010000000
VERSION     DACDAF010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.102"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            132..953
                     /gene="racE"
                     /locus_tag="IVZ69_002357"
     CDS             132..953
                     /gene="racE"
                     /locus_tag="IVZ69_002357"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HAP8184392.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            956..2311
                     /gene="rph"
                     /locus_tag="IVZ69_002358"
     CDS             956..2311
                     /gene="rph"
                     /locus_tag="IVZ69_002358"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HAP8184393.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            2312..2830
                     /locus_tag="IVZ69_002359"
     CDS             2312..2830
                     /locus_tag="IVZ69_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HAP8184394.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            2937..3437
                     /locus_tag="IVZ69_002360"
     CDS             2937..3437
                     /locus_tag="IVZ69_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HAP8184395.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(3717..4637)
                     /locus_tag="IVZ69_002361"
     CDS             complement(3717..4637)
                     /locus_tag="IVZ69_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HAP8184396.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            4802..5815
                     /locus_tag="IVZ69_002362"
     CDS             4802..5815
                     /locus_tag="IVZ69_002362"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HAP8184397.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(5925..6680)
                     /gene="fabI"
                     /locus_tag="IVZ69_002363"
     CDS             complement(5925..6680)
                     /gene="fabI"
                     /locus_tag="IVZ69_002363"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HAP8184398.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            6900..7340
                     /gene="fabZ"
                     /locus_tag="IVZ69_002364"
     CDS             6900..7340
                     /gene="fabZ"
                     /locus_tag="IVZ69_002364"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HAP8184399.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(7455..8216)
                     /locus_tag="IVZ69_002365"
     CDS             complement(7455..8216)
                     /locus_tag="IVZ69_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HAP8184400.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            8405..9499
                     /locus_tag="IVZ69_002366"
     CDS             8405..9499
                     /locus_tag="IVZ69_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP8184401.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
BASE COUNT         3110 a         1679 c         2005 g         2778 t
ORIGIN      
        1 taaagtcaca accgcttttc ctctttccat tcgaaaaaaa gagatttcga ttgttttaag
       61 caagtaagag cacttgaaaa ttcacgctaa aaagtacaca atagggagga tagaatttat
      121 tgaaaaaaag gatgatacga ttgacagata atcgccctat cggatttatt gattcaggtg
      181 tcggcggctt gactgtagta aaagaagccc tgaaacaatt accgaatgaa aatattttat
      241 ttgtaggaga cacagcacgc tgcccatatg gccctagacc cgcggaacag gtaatccagt
      301 atacttggga aatgacggat tatctggtgg agcaaggaat caagatgctg gtgatcgcct
      361 gcaataccgc aactgcggtg gctttagaag aaatcaaagc tgctctttct attccagtca
      421 tcggtgtgat ccttcccggt actagagcgg cagtaaaaaa aacacaaaat aaacaagttg
      481 gcattatcgg tacgattggt acggtaaaaa gtcaagctta tgaaaaagca ctgaaagaga
      541 aagtaccaga attgactgtg acaagtcttg cttgtcccaa atttgtttca gttgtcgaaa
      601 gtaatgaata ccattcatcg gtggcgaaaa aaattgtggc agaaacatta gctcctttaa
      661 ccactaaaaa aatcgataca ttgattttgg gatgcaccca ttatccatta ttacgcccca
      721 tcattcaaaa tgtaatggga gaaaatgttc aactgatcga ttctggagca gaaacagtag
      781 gtgaagtatc tatgctgtta gattatttca atttgagcaa ttcaccgcaa aatggtcgga
      841 cattatgcca gttttataca actggctctg ccaaactttt cgaggaaata gctgaagact
      901 ggcttggaat cggacactta aatgtagaac atatcgaatt gggaggaaaa taaggatgcg
      961 tcatgacggg agaaaagccc aagagcttcg caaactggag cttcaaacaa atgttttcaa
     1021 atatccagaa ggatcggtag tgatccgttt tggtgataca acagttattt gttctgcaac
     1081 aatagaaaat tctgttcccc cttttttgag agaaacagga acaggatggg tgacagcaga
     1141 atatagtatg ctgcctcgag caacgagtac gagaaatcgt agagaaagca gcaaagggaa
     1201 actttctggt agaacaatgg aaatccagcg tcttattggt cgttccttgc gtgcagtagt
     1261 agacttggaa aaattaggag aacgtagtat catcgtagac tgcgatgtga tccaagcgga
     1321 tggcggtact agaacagcaa gtatcactgg ggcatttgtg gcattgaaat tagccattga
     1381 aaaactttta agagaaaaag aattgtcaga agatccaata aaagaacatc ttgctgcagt
     1441 tagcgtagga atcttaccag atgggacttg cgtcacagat ttggattacc aagaagattc
     1501 cgcagcactt gtagacatga atcttgtaat gacagaatct ggaaaattcg tggagattca
     1561 aggaactgga gaagaagcaa cgtttgatgg tgaacagttg aatgaaatgc tcttttttgg
     1621 aaaaaacgcg attgaagatt tgatcaaaga gcaaaaacat gctttgctaa cagagtttgc
     1681 tcaaaatgat gagcggatag aagaaacaaa aacaatcatc attgcgacaa gaaatccagg
     1741 aaaagcagaa gagtttcgaa atatgttcaa agaagcggga tatcatgtaa aaacattact
     1801 tgactatcct gaattgccag atgtggaaga aactggcagc acatttgaag aaaatgcccg
     1861 attaaaagca gaaacgattg cacaattgct tgatcagcca gtcttagcag atgattcagg
     1921 tttgaaagtg gatgctttag gcggtatgcc aggaatctat tctgcacgtt ttgcagggga
     1981 acaaaaaagt gatgcgggga ataacgccaa attattatat gaattgacag atgtgccgga
     2041 tgaaaaaaga acagcacaat tccattgtac gttagtattc gcggcaccca aaaaagacag
     2101 ccttgtagta gaagcggaat ggcccggtcg agtagcccgt ataccatctg gcgaaaatgg
     2161 ctttgggtat gatcctttat ttatcccaga aggtaagaaa caaacagcag cagaattatc
     2221 gagcgaagaa aaaaacaaga tcagtcatcg ggctcaagca atgaaaaaat tgagtgccga
     2281 gtggaaacaa tggctggaag gagagagata gatgcggtat ttagtagtaa gtgataatca
     2341 tggagacaga gatatcctcg ttgacttagt agatcgttat cgttctgaag tggatatctt
     2401 tttccattgt ggtgattcgg aattagaagc ttctgaccca ttatgggata cattccaagt
     2461 ggttcaaggt aattgtgatt atggaccagg attcgaacag aaaaaagtga tccaaactgg
     2521 tcaggataca gtattcatga ctcacggtca tttatcgaat gtccgatttg gtttgacaca
     2581 gttagcaatc gaagctcgag ctgcaactgc cgatatggtg ttttttggtc atacccatca
     2641 aataggctgt gagatggatc agaaaatcct gtttttgaat cctggtagca tttctcagcc
     2701 tagaggcccg atccaaatcc catcatatgc tcttatcgaa agtttagatg accaaatttc
     2761 tgttcaatac tataaccgtg cccatcaggc agttgaagag ttggcctttt ctttttcgag
     2821 agagcgctga ataaaaaaac tctaattttt aataaaaata agctttattt tatgaatttt
     2881 gcatccggtt tcggtaaaat agtagtgttg aatgaaatag aaatggaggc catcagatga
     2941 ttggacctat agtaagagaa atgctgctgg aaaatcagga aacgtttttg attcctgcag
     3001 aaaatgtggc aaatgttatg tatcatcatc cattgtccca tggtttactt gtgttatcga
     3061 aggtcggtta ttccaaaatt cctgtattag gaaaagatga tcactttgta ggactagtaa
     3121 gtttatcaga tgtggtcaat aaaatgattg acttgcaaac aatcagcatg gacccgttag
     3181 aaggactaac ggttgctgat gtgacagaaa cagatgttcc gacaattgat gaaaattggg
     3241 aactagaaga agtactccat ttgttagtcg attcgccttt tttaccggtt gtcacagaag
     3301 atcggatttt caaaggaatc attacaagaa aagagctgct taaagccgta aacttcatgg
     3361 tgcatgaatt agaacgtcgt aatatattgt ctccgaaaat cgaagaatta aaagaacaaa
     3421 tcgatatcgt gagctaaaga acgagaaact aaaagataat caaaaaataa gtagaaaaaa
     3481 cagcgtacca gttttgactt tatcttgaaa aagaggctgg gacaaaagcg tttaactcca
     3541 agaaataaga aggaattcac gaaaattgct tttcaaattt ttgtgaattt cagcttattt
     3601 ccgaaggagt tgcttctgct tccgccgttt atacgtgttt agagcgtggg acaaaagtgt
     3661 tctttacttt tgtcccacgc tctttttagt gagattcgtt gcatcgtttg tccaaattat
     3721 tttccgacag caattggact gttcggaatc gtgaaaccag aagctgtcaa ttctttgaca
     3781 taggagctca agaactcttc ttttaaggca tattgttttc cgttcaatgc gtagcagacc
     3841 gtacgaatcg caaaattgct gtttccaaga tccactaatc caaagataga aggttcagtt
     3901 tggagctctt cttggtattt ttcagctaat gtacgattta ctcgatcaat gatctcatag
     3961 attttgtcat atccttcttc aggaacaatc cgaatatcta aaagtacttg catatttgca
     4021 cgagagagat tgctgatcgt ggtgatgttt cgattcggga tgaaatggac agtaccatcc
     4081 gttgctttca gctgaagggt acggatacca acagatacga cggttccttc aatcgttaag
     4141 tttgctagct tgatgtagtc cccaacatcc atctgttgtt ccatgataat aaaaaatccg
     4201 gtaataacat cactcatgaa cccttgggca ccaagaccga ttgccacacc tgcaattccg
     4261 gcaccagcca aaagtgatcc gatcggcaca ccgatagcag ataaaattgc atagataaaa
     4321 aagaaaccaa gggtataatg aaaaatagta tttaaaagac tatgtaaagt ctttaagcgg
     4381 ctctcgttta gaatggcttt tttagaatac tgattaaaag acttatcaat cagatatttt
     4441 cccacacggt gaagaatcca aaaaaggacg atcaaaaaaa tcagatataa acttttttgg
     4501 ataaaggcag ccaaaatggc gtcccaatca atcccgtccc aaaaccgctg aaacgcattt
     4561 actttgctga cagcttgatc tgtcaatgtc tcgccagaag agtctgtcgt accggcagtt
     4621 gctaataatg aaaacataaa atcctctttt ctaaaatttg attctttctg tattgtacca
     4681 agaagttttc aaaaaaggaa atagcaaaaa taactataat gaaggaaaaa agctgaaaat
     4741 aaaatgacaa ataatatgga taatgataaa atgtggagaa aataacgaag gtggtaagta
     4801 tatgcaaatc gattggaaca atctaggttt ttcttatatc aaaactcctt ggcgttttat
     4861 tgccaaatgg aaagacggac aatgggaaga aggagaattg acagaagata attacctgac
     4921 gattcatgaa ggctctccag cgcttcatta tggtcagcaa tgttttgaag gtctaaaagc
     4981 ttatcgtcga aaagacggca aggtcaatct ctttcgacct gaacaaaata gtcgacggat
     5041 gaatcaaagt gctagacgat tgctgatgcc aatggtccct gaaaagatgt tcgttgatgc
     5101 tgtcaagcaa gtggtaaaag caaatgaaga ttttgtgccg ccctatggaa caggcgctac
     5161 attatacttg cgccctttac tgattggggt cggtgaaaac attggtgtcc atccagctcc
     5221 agaatattta tttgtcgtct tctgtacgcc agtaggagcg tatttcaaag gtggactaaa
     5281 accaacgaat tttattgtat ctgattacga tcgtgctgct cctaagggga ctggtgcagc
     5341 aaaagtcggc ggaaattacg cagcgagttt acttccagga acagaagcaa aagaactgga
     5401 ttactcagat tgtgtttatc ttgatccagc cacacatacg aaaatcgaag aagtaggtgc
     5461 agcaaatttc tttggaatta caaaagacgg aaaattcatc actccgcaat cgccctctat
     5521 cttaccaagt atcacgaaat attccttgtt gcagttagct gaagaacgac taggactgca
     5581 agcaattgaa ggagatattt tcattgatga tctagatcaa tttgcagaag ctggtgcatg
     5641 tggtacagcg gctgttattt ctccaatcgg tgggatttat cacaataaca atcttcatgt
     5701 attttatagt gaaacggaag taggaccagt aacaaaacgg ttgtatgatg aattgacagg
     5761 tattcaattt ggagacatag aagcaccaga aggctggatt gaagtcgtgg aataatttca
     5821 aagtaatgag ttgaaaaaaa cgtaaaaaga aaaaatcagg aagagacttt aaaaagtttt
     5881 ttcctgattt ttatatgttt tactttaaag aatgcaacaa aagtttatga aagatggaca
     5941 cctttgtcaa cgtagataat atcaccgatg attccgctgg aaagtgggct gattaagaaa
     6001 gcacaagcat taccgacttc ttcgatcgtc acaccttgct gatcaggcgt acgagattca
     6061 gataactgga tcagtttttg atagtcttta acacctgtga cagctaatgt tttgattgcc
     6121 ccagctgaga ttccattgac ccgaattcct ttaggcgaga actcagctgc caaataacgg
     6181 atagcagctt caagagaagc tttcgcaata cccatcatgt tataattcgg gattgcgcgt
     6241 tctgaaccta gataagtcat gctaacgatc ccgctgtttg gtgcaagaaa cggttgtgcg
     6301 tattttgata cagcaattaa agagtagctg ctgatatctt gagctaattg atagccgtct
     6361 ctggaaatat cagacacatt tccggacaat tcttctttgt tggcgtaagc aactgcatgg
     6421 acaaggccgt ggatctcccc agcatattca ccgatggcat tcattgcttt ttcgatgctt
     6481 tcgtcgctag aaacatcaca ttctacagtg aatgcttctt cgccgaccaa tttgactaat
     6541 gattttttca ttcgttcatt ttggtaagta tagataattt ctgccccttg tttcaacatt
     6601 gcttcagcac aaccccaagc aatgcttttt ttgttagcga cgcccataat gacgattttt
     6661 tttccttcta gaaatgacat aatgactctc ctttgtttct gataaaaatt tgatagtcgt
     6721 aaaaaaatag agaataatag ctaaaataac ttcttgattt cttaattatt agtcaaaatg
     6781 ttttgattgt caaactattt tttcttaaat taaaaaaaga ttgctaaata tttaggaata
     6841 tgatactttg atagtcaaag taatgaaaat ggcaattgcc tgaaagaagg agtttaatta
     6901 tgtcttacgt attatctgct actgaagtaa tggaattgat tcctaatcgt tatcctattt
     6961 gttatattga ttatgtagat actttagaac caggaaaaaa gatcgttgcg acaaaaaatg
     7021 taacaatcaa tgaagatttt ttccaaggtc actttcctga caatccagtg atgccgggtg
     7081 cgttgattct agaaacactg gcacaagcag gttcgatact tatcctaaaa tcagaagagt
     7141 ttctaggaaa aagagcttat atcggtggga tcaataaggc caaattccgt caaaaagttg
     7201 ttccaggaga tgtgctgaaa tgtcattttg aaatcaccaa aatgaaggga tcagtcggta
     7261 cagcgttatc tgcagcatat gtagatgata aaaaagtctg tgagtgcgag ttcacgttca
     7321 tcgtcaacca aaatgcttga ctataaaacc tgatatagca aaacaaaagg aagcttactt
     7381 gctttttatg taaaaagaag acgcctgaat cctagcatac gttgtcatct atgcaggatt
     7441 cagacgttat ttttttattt ttgttttgct tcttgcagta tattgatttt atcgattttt
     7501 acttcttctt ttggtttgtc tgaactatct gtttcgatat ttgcaatagc atccacgaca
     7561 tccattcctt caatcacttg gccgaagaca gtataatggc catctagtga aggataaccg
     7621 ccgtttttat aagcgtcgat gattgcttga ggatagtcgt cttttaaaag accatcatgc
     7681 atatcatctg tattttgaac gataaagaac tggctgccgt tactgttagg atcttgtgag
     7741 cgagccatag ataacgcacc tcttatatta taaaggtggt tgttgatctc tgtttcaaat
     7801 ccttctcccc aaatgctttc ccctccagtg ccatcgcctt taggatcgcc accttggatc
     7861 atgaaatctt tgatgacgcg atggaaagtc agtccgttgt agtaaccgtc ttttgcatgt
     7921 gtcataaagt tttcaaccgc ttttggtgcg tgttcgggaa ataatttgat tttgattgtg
     7981 cctttattcg tcaccatttc gaccagatct tcattttcgg cgacatcttt cgtcaattgt
     8041 ggtaattcca atgcgttcaa atcgacgcta ctggcagtcg tgctttccgc agtagatgta
     8101 ctttttgaac tttctgtaga cgaactagaa gaagtcgtgt tgtttgcaga acaaccagca
     8161 gcaaacagca atgctgctgc taaactaata cttaaaataa ctttattttt cttcataact
     8221 gttcctttcc aatttactat tttgttatct ttaatgataa caaaatagag ggaaaatacc
     8281 tacttaaatt attggaattt atcatttatt ttaaaagaaa aagaaaaggt gtagaccatt
     8341 tactttgtgt ttgctataat gtaagtggat acaaaaacga aaagatgcag gaggaaatgg
     8401 taatatggga aaattaggaa tctcgattta tccagaacgg tcaacatttg aaaaggacaa
     8461 agcgtacttg gatttagctc ataagtatgg gtataaacgg gtttttacca gtttgctgca
     8521 gatcaatgat gataaagaaa aagttctttc agaatttaaa gaagtagttg attacgcgaa
     8581 tagcctaggc atggaagtaa tggttgatat caatccagcg ttatttgaac agttggagat
     8641 ttcttacgat gacttatctt ttttccataa gatgggtgcc tacggggtcc gcttagatat
     8701 cggattcaca ggagcagaag aagcaaaaat gacgcgcaat ccttttggta tcaaaatcga
     8761 gatcaatatg agttcgggca cgaattacgt tgacaacatc atgagttatt cgccaaacac
     8821 ggataattta ttaggttctc ataattttta tcctcatcga tactctggtt taggatacga
     8881 acactttgtt ttttgttcag aaaaattcag aaaatataat ttgaatacga tggcattcgt
     8941 caattcgcaa tctgctgagt ttggcccttg gcctacgcaa gatggcttgt gcacgctgga
     9001 agaccaccga gatcttgaaa ttgcgacaca agtgaagcat ttaatcctta caggattgat
     9061 tgatgatatt tctattggaa atgcgtacgc aagtgaagaa gaattgaaag aaatggcaga
     9121 agcatttaac gcggattatc caacattgaa agtagatacg gaagaaggta ttacagaaaa
     9181 cgaacgaatc tgcttgtttg ataaccttca tagttatcga ggggatcgct cagaatatat
     9241 ccttcgttca acgatgactc gtgtatacta caaagataaa gatttcccgc ctcataatac
     9301 gcgagatatg catcatgggg atgtactgat tgacaatgaa gggtacggtc aatacaaagg
     9361 agaaacacaa atcgccttga aggatatgaa aaacgacgga cgtgtcaatg ttgtaggaag
     9421 aatctccgat gacgaattat tcctccttga ctttttgaaa ccatggtcaa gctttaaatt
     9481 aattgaaaat aaaaaataga taattagtta ttgcagaaat aatccgctag aaatagccag
     9541 ttatttctgc ttttttattt tgttttttta ta
//
LOCUS       DACDAF010000100         9219 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.103, whole genome shotgun sequence.
ACCESSION   DACDAF010000100 DACDAF010000000
VERSION     DACDAF010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.103"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            23..646
                     /locus_tag="IVZ69_002367"
     CDS             23..646
                     /locus_tag="IVZ69_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184402.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="IVZ69_002368"
     CDS             1096..2145
                     /locus_tag="IVZ69_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HAP8184403.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="IVZ69_002369"
     CDS             2142..3023
                     /locus_tag="IVZ69_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8184404.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="IVZ69_002370"
     CDS             3026..3796
                     /locus_tag="IVZ69_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8184405.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="IVZ69_002371"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="IVZ69_002371"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HAP8184406.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="IVZ69_002372"
     CDS             5107..6270
                     /locus_tag="IVZ69_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HAP8184407.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="IVZ69_002373"
     CDS             6387..6797
                     /locus_tag="IVZ69_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP8184408.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="IVZ69_002374"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="IVZ69_002374"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP8184409.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
BASE COUNT         3196 a         1575 c         1998 g         2450 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcg
//
LOCUS       DACDAF010000101         9172 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.104, whole genome shotgun sequence.
ACCESSION   DACDAF010000101 DACDAF010000000
VERSION     DACDAF010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9172)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9172)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9172
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.104"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            949..1422
                     /locus_tag="IVZ69_002375"
     CDS             949..1422
                     /locus_tag="IVZ69_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HAP8184410.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="IVZ69_002376"
     CDS             1431..1658
                     /locus_tag="IVZ69_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184411.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="IVZ69_002377"
     CDS             2294..2665
                     /locus_tag="IVZ69_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184412.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="IVZ69_002378"
     CDS             complement(2921..3163)
                     /locus_tag="IVZ69_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP8184413.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="IVZ69_002379"
     CDS             complement(3195..4097)
                     /locus_tag="IVZ69_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP8184414.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="IVZ69_002380"
     CDS             complement(4110..4298)
                     /locus_tag="IVZ69_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP8184415.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="IVZ69_002381"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="IVZ69_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP8184416.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="IVZ69_002382"
     CDS             complement(4913..5806)
                     /locus_tag="IVZ69_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP8184417.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6822)
                     /locus_tag="IVZ69_002383"
     CDS             complement(5884..6822)
                     /locus_tag="IVZ69_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HAP8184418.1"
                     /translation="MRYYFVDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPD
                     DIFVGTEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLI
                     TCIDRKTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAAR
                     KTTENEELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQ
                     RQTEKMIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTG
                     GLPGKSSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="IVZ69_002384"
     CDS             complement(6856..7206)
                     /locus_tag="IVZ69_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP8184419.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="IVZ69_002385"
     CDS             complement(7239..8141)
                     /locus_tag="IVZ69_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP8184420.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="IVZ69_002386"
     CDS             complement(8134..8991)
                     /locus_tag="IVZ69_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HAP8184421.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
BASE COUNT         2571 a         1736 c         1509 g         3356 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca tctttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtt gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt ga
//
LOCUS       DACDAF010000102         8804 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.105, whole genome shotgun sequence.
ACCESSION   DACDAF010000102 DACDAF010000000
VERSION     DACDAF010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8804
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.105"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..239
                     /locus_tag="IVZ69_002387"
     CDS             <1..239
                     /locus_tag="IVZ69_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HAP8184422.1"
                     /translation="LYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLNEARNRHS
                     LAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            306..800
                     /locus_tag="IVZ69_002388"
     CDS             306..800
                     /locus_tag="IVZ69_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HAP8184423.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            856..1494
                     /locus_tag="IVZ69_002389"
     CDS             856..1494
                     /locus_tag="IVZ69_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184424.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            1566..1961
                     /locus_tag="IVZ69_002390"
     CDS             1566..1961
                     /locus_tag="IVZ69_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP8184425.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            1945..4398
                     /locus_tag="IVZ69_002391"
     CDS             1945..4398
                     /locus_tag="IVZ69_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HAP8184426.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            4395..6422
                     /locus_tag="IVZ69_002392"
     CDS             4395..6422
                     /locus_tag="IVZ69_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184427.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            6419..7441
                     /locus_tag="IVZ69_002393"
     CDS             6419..7441
                     /locus_tag="IVZ69_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase P60"
                     /protein_id="HAP8184428.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDDETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            7458..8387
                     /locus_tag="IVZ69_002394"
     CDS             7458..8387
                     /locus_tag="IVZ69_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP8184429.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            8632..8748
                     /locus_tag="IVZ69_002395"
     CDS             8632..8748
                     /locus_tag="IVZ69_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HAP8184430.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
BASE COUNT         2978 a         1479 c         1759 g         2588 t
ORIGIN      
        1 aattatatag taggatacaa caattaattg aaaaagaaat tcaacctact gaacttgctg
       61 atatagtgaa gacaacgata aggtcatcaa atggaatgat tagctctctt aatgaagcaa
      121 gaaataggca ttcacttgca caccctaata caaatattat tggaaagaga gaagcaaaac
      181 taataatagg tatttcaagt acagttacag attatattag cggatacctt gataagtagc
      241 gtcattaact gattgctact ttttttatga ctatttttat aaaaaggatg tgataagaat
      301 tggaaatgaa agtctatgtg gcaaatttag gacggtataa tgaaggtgaa ttagtcggag
      361 catggtttac tccaccaatt gatgaggaag aaatggcaga aagaatcggt ttaaatgagg
      421 actacgaaga atatgcaata catgattttg agcttccttt tgatgtggac gaatacacgc
      481 cgattagtga aatcaaccgt ctatgtgaag ccattcaaga aatcgaaggt acacctattt
      541 ataatgaact caaagaaatt caaggcatgt ggtttagtag cttggaagaa ttactggaaa
      601 acaaagagga tattcattgt tatagtgatt gtgattcgat ggaagatgtc gcccgttatt
      661 acgtggaaga aacaggacag cttggtgaag tcccttccaa tttacaaaat tatattgact
      721 accaatcttt gggacgtgat atggaaatag agggtaatta cctagttacc tctcatgggg
      781 tatttgaata ttgtcagtaa gtttaacaat ccgtgttata attaaattaa taaatagcac
      841 ggagaggtat aaattatggt aaatgtattt gaaaatctta aactattaaa actagacatg
      901 aaagataaag gctgggtgat agattccttt tactttcgtt acaaacagca aaattatatt
      961 gtacttgtta agctatttga aaaagaggaa aaagttccag aatatgctct gttaaaacta
     1021 gaatttttaa aggaaaacga tttttcagat atgctagctg tctatgctaa ttcggtaaaa
     1081 ttatatacag acacgaaaac aataagagaa tattttggta tcgaatacag tagtaacttg
     1141 ggagatgttt tatttcaatt tagccaaact cttgctcgat ttattccgac agaagttagt
     1201 gagaagaaaa atgaagacca aaaagaagcc atgtgtttct cattaagtca aagtgattca
     1261 gaagatccca gaaaaaaata ttgtttttca gttagaagaa atcctttaaa gggaaatggt
     1321 gagctgggaa aacgaagtcc ttttaatgac aataaaacga gattgtatag acccagctta
     1381 tatgaacgat tagggtcaga taccaattta agtttcagat attcaatgaa tccagatgat
     1441 gaagaaactg atgaaggtat tattgcaaaa tggacaaaaa ataaaattga atagttaaag
     1501 cattgaaaga gcaatcacct attttgattg ttctttttct atttttacgg aaaggacgtg
     1561 aagacatgaa aaaaataaga agttacacca gtatttggtc agtagaaaaa gtgatttatg
     1621 cgattaatga tttacaactc cctttcccaa ttacctttac gcaaatgaca tggtttatcg
     1681 tttctttgtt tgtcgtcata ctctttggca gtttaccacc actttctctg attgacggag
     1741 cactactcaa atacttaggg attcccattg ttctcactgg gttcatgtgc caaaagacct
     1801 ttgacggaaa gaaaccctat ggatttctaa agtctatcat tacctatgct ctacgcccta
     1861 aagtaaccta cgctggcaaa caaatacgat taaaaaaaga aacaatgaat gaatcgatta
     1921 cgattgtaag gagtgaacaa ctagatggca tatccgatta aatatatgga agataatctc
     1981 gtatttaatc atgatggcga agtattcgct tattatgaat taattcccta taattacagt
     2041 tttttaagtt ccgatgaaaa aattcaagtt catgataatt tctgtcaatt gattgcccaa
     2101 aatcgtgatg gcaagattca tgctctgcaa ctagcaaccg aatcaagtat tcgagccaca
     2161 caggaacaat cgaaaaaaga aatcactgga cgattaaaag agatagctta cgaaaaaata
     2221 gatgaacaga ccgaagcgtt aatttctatg attggtgaca atcaagtaga ctatcgcttt
     2281 tttattggtt ttaaactcta cctcaatgaa caggaagtat ccgtaaaaaa tgttgggaaa
     2341 gaaattcaaa aagcatttgc ggaattcttt catggtgtga atcacaaatt aatgggcgat
     2401 tttgtttcta tgcctatggc ggaaatcgaa cgcttttcta agatggaaca gttgttagaa
     2461 agtaaattat ccagacgctt tcagattcgt aaattggaga aagatgattt tggttatatt
     2521 attgaacatc tttacgggca aacaggtgtc ccttttgatg actacgacta ccatttaccg
     2581 aaacgatacg aagataaaaa agtgttggta aagaaatacg atattctcaa acccactcgc
     2641 tgtttaatcg aagaaaatca acgctattta cggattgaac aggaagatac cactacttat
     2701 gtggcgtatt ttacaattaa tagtattgtt ggtgaattgg atttccctaa tagtgaaatt
     2761 ttttattacc agcaacagca gtttactttc cccgttgata ccagtatgaa tgttgaaatt
     2821 gtcgccaata aaaaagcctt atctaccgtt cgcaataaaa agaaagaact gaaagattta
     2881 gatagccacg catgggaaag cgacaacgaa accagtacta atgtggtgga cgctttagaa
     2941 tctgtcgatg aattagaaag taatttagac caaaccaaag aatctatgta caaactaagc
     3001 tatgtggtac gggtatcagc aaagaatttg gacgagctga aacaacgttg tgatgaagta
     3061 aaagattttt atgatgatct gtctatcaaa ttagtacgac cttttggcga tatgctaggc
     3121 ttgcataatg aatttattcc ctcaagcaag cgatatatca atgactatat tcaatatgtc
     3181 acgtcggatt ttttggctgg tcttggtttc ggtgctacac aaatgattgg tgaaaattct
     3241 ggtatttacg tcggttacaa tctcgataca ggcagaaata tttatctcca acctagcctt
     3301 gcaagtcaag gaattaaagg ctctgtaaca aatgcattag cgtccgcttt tattggttca
     3361 ttaggtggcg gaaaatcatt ctctaacaat atgctggtct attattcagt actctttggc
     3421 ggacaggcaa ccattgttga cccaaaagct gaacgtggtg aatggaaaga aaccttacct
     3481 gatattgccc atgaaatcaa tattgttaat ctcacgagtg agaacgacaa taaagggtta
     3541 cttgaccctt atgtgatttt aaaactcccg aaagattcag aaagccttgc cattgatatt
     3601 ctcacgttct taacaggtat ttccagccga gatagcgaga agtttcctgt cctgcgtaaa
     3661 gctattcgga gtgtaactca aagcaaacaa cgagggttgt tattggtgat tgatgaattg
     3721 cgaaaagaag atacgcccat cagcaatagt attgctgacc atatcgaaag ctttgtcgat
     3781 tatgattttg cccatctgtt attcagtgat ggcagtgtca cccaatccat tagcttggaa
     3841 aaacaactca atattattca agtggcagat ttggtcttac ccgattccaa tagctctttt
     3901 gaagaataca ctaccatgga attattaagt gtggcaatgc tgattgtcat tagtaccttt
     3961 gctttagact ttatccactc tgaccgttcc atttttaaaa ttgttgacct tgatgaggct
     4021 tggagttttt tacaagtggc acaaggaaaa gctctatcta tgcgattggt tcgagcagga
     4081 cgtgccatga atgcaggggt ctatttcgtt actcaaaacg cggacgattt actagatgaa
     4141 aagatgaaga ataatattgg cttgaaattt gcctttcgtt ccactgacct agtggaaatc
     4201 aaaaagacct tagaattttt tggtgtggac aaggaagatg aaaacaatca gaaacgctta
     4261 cgtgaattag aaaatggaca atgtttagtt tcagacatct atggtcgtgt aggggttatg
     4321 cagtttcacc cgatttttga agagttgctt catgcctttg ataccagacc gcctgtgcga
     4381 aatgaggtgg aagaatgaca caaaaacaaa agaaatttct tcactatagt tggataacgc
     4441 tcctttgtgt gggcgttatt ttacttttat taggcacgct gggcaatgca gtacaagcga
     4501 caggcttagt tgatgaaacc attgatacaa gcaatgaata ctccaagtat ggtttgaatc
     4561 aatatcagct tgattattat gtggacaata gctggggctg gcttccatgg aattggagtg
     4621 atggcatagg acaatcggtg atgtatggat tgtatgccat tactaatttt atttggacaa
     4681 tttctcttta tctatcgaac gccacaggtt atttggtgaa agaagcctat gccttagatt
     4741 tcattagtca aacatcccaa gcaattggcg aaaacatgca gacgattgca ggcattacac
     4801 cgaatggctt ttccagttca gggttttatg tcggtttcct ccttcttttt attctcattg
     4861 ttggaatcta tgttgcctat acaggattgg ttaagcgaga aacgacgaaa gtgatacgag
     4921 ctgttttaaa ctttgtcgtg gtgtttattc tatcggcttc ctttattgcg tatgcacccg
     4981 attatattgc gaaaatcaat gatttttcca aagatgtcag taccgccagt ctgaatattg
     5041 ggacaaaaat tgttcttcct aacacggata gtcaagggaa agacagtgtg gacatgatac
     5101 gtgacagctt attctctgtt caagtaaagc aaccatggct attgcttcaa tatggctcca
     5161 ctgatgtaga agcgttaggg gaagaacgtg tggaaagttt attgtctacc agtccagata
     5221 caaacaatgg tgaagataga gaaaatgtag tgattgaaga aattgaagat catgacaata
     5281 cctatttaac cctaccgaag acgatttcca gattaggaac agtcttcttt ttgtttgtat
     5341 tcaatattgg tatctcgatt tttgttttcc ttctaacagg aatcatgatt ttttcgcaag
     5401 tgctatttat tattttcgct atgtttttgc caatcagttt cctattaagt atgttgccga
     5461 gttttgatgg catgggcagg catgccatta ccaagttatt taatgtgatt atgacaaggg
     5521 ctggtattac cttgattatt accgttgcct ttagtatttc cactatgctt tattcgctgt
     5581 cagcaagttc tccctttttc atgattatgt ttttacaaat tgtgaccttt gcagggattt
     5641 attttaaact gggcgattta atgagcctat tcactttaca aagcaacgac tctcaaaaca
     5701 tgggcagaca agtgtttcgc agacctcgtc aaatgatgaa tcgacaaacc agaagatttc
     5761 aacgcagtat gagtaagatt tttcgtggaa aagcagggtc aacgaagcaa aagacaatga
     5821 caacaaagca gaatcaaacc aataaagcta accatactcg tcaaaatgaa cggactacac
     5881 caaagaaaga aacagcactt tccaatgtga aaaagcaaca aggcggtatc gggcaacgat
     5941 taggtgaaaa gacagcccat gtattggaca cgaaaaatcg tctagtcaat aaaagaaagc
     6001 aggcaaaaca acagatacag gcgacaccaa cccatgtcaa atatgccctt catcaaggaa
     6061 aagagaatgt cactcataat gtaacagact ttaaacaatc tatggcagat accaaagctc
     6121 aacgcaaaca acagcgtatg aaccagcagg agcaaaaacg aaagaacatt gctcaaaagc
     6181 gtttggagct ggataaagca aaagaaaaaa gacgaaaaga aaacccatca tctcctgttc
     6241 agaataacca gcagcatgtt cgcaagcgtc agcaaaccgt cacgcctgtt ttgtcacaaa
     6301 acactaaacg tgaaaatcat cagcgaccat tgaaaaaaga gcaaaaacaa aagacaccac
     6361 cgaagcaatt caatcagagg aagctaaata aaagaacgga taagcgagga caacaaacat
     6421 gaagctaaaa ataacagtga tttgtagtgt ggtcttctct ctcttctttt ttctcttatt
     6481 attcctagtc attttctttg cagatgatac ggacagtggc gaaaacaaca aggattcttc
     6541 tattccacaa ggcggtgtga ccgtttcacc agaagtgttg gcacaccgtc cgttgattga
     6601 aaaatatggt aaggaatatg ggattgaaga ctatgtttct tatatcttag ccattatgca
     6661 agtggaatcg ggcggtacag cagaagatgt tatgcaaagt tccgaatctt tgggtttacc
     6721 gcccaacagt ttgagtaccg aagagtccat caaacaaggg gttaaatatt tcagtgaatt
     6781 attaaccagt gcagaacaac aaggagtgga tatagattct gttatccaat cttataatta
     6841 tggcggtggc tttttaaatt atgtgaggag tcatgggaaa aaatatacct atgaattagc
     6901 cgaacagttt tctaaagaga agtcgggtgg tcaaaaagca gactatccca atcctatagc
     6961 catacctgtg aatggtggtt ggcgatataa ctatggaaat cagttttatg ttcagttggt
     7021 ttcacaatac ctaaccgaca cttccccaac agaatttgat gatgaaaccg tgcaagtcat
     7081 tatggacgaa gccttgaaat acgaagggtt tccctatgtc tttggagggg cgtcgcctac
     7141 cacctctttt gattgtagtg gcttaataca atgggtgtat gacaaagctg gcatttctct
     7201 ccctcgtgtc gcccaagatc agtatgacgc tacgcaagaa atctctatgg aagaagccca
     7261 agcaggcgac cttatcttct ttcattcaac ctataatgca ggcacatatg tgactcatgt
     7321 ggcgatatat ttagagggaa atcgctttta tcatgcaggc gacccaatcg gttatggcga
     7381 cttaagcagt cgttattggc aagaccatct gattggggct agacgtgtta ttcataacta
     7441 agaaaggaat gaatcaaatg attataaaaa tcgagcgaaa agaaaagaag gagaaaccaa
     7501 agaaatctaa aaaaccgagc aagcaaagaa aagttccgat gattaaagtt ggcacgcata
     7561 agaaattaac ctttgtttta tgggttttat tgattggtag tgtcggattt ggaatctata
     7621 aaaattttac tgccattgac actcatactg tccgtgaaac agaaatcatt aaacagcaga
     7681 ttgtcgatac caaccaagta gaaagttttg tgaaatcctt tgcgaaagac tacttttcgt
     7741 ggcaacaatc ccaagaagcc attgataaac gaaatgaaaa attgacccat tatttgacgg
     7801 aagaattgca ggtattaaat gaagaaatga ttcgtaagga tattcctact agttctagtg
     7861 tgaacgatat acaggtgtgg caggtttctc aagtgaatga gaacaccttt gaggtactgt
     7921 tttctgttga acaagttatt accgaagaca aagacaagga aactatatcg tctagctttc
     7981 atgtggttgt ccatatagat gaatcagata atatggttat tatcaaaaat ccgacaatga
     8041 gtaagaaacc tcaaaaatcg gactaccaac ccaaacagct agaaagtgac catacagtag
     8101 atacagaaac gatggacgaa atcactagct ttttagaaac gttcttccag ctctatccta
     8161 ccgccacaga aaaagaattg acttactatg taagtaatca tgtgttacct atgattaaca
     8221 aggaatatgt tttcgaggaa ttggtgaatc ctatctttac cagaaaagat aaccaagtaa
     8281 tcgtgaatgt cgctgtgaaa tatttagatc aagaaacaaa ggcaacccaa atctcgcaat
     8341 ttgagttgat attagaaaaa caagataatt ggaagattgt aaaataacaa atattggtac
     8401 atgattacag atactttgta atcatgtact ctttttgata aaaaattgga gattccttta
     8461 caaatatgct cttacgtgct attatttaag tgactattta aaaggagtta ataaatatgc
     8521 ggcaaggtat tcttaaataa actgtcaatt tgatagcggg aacaaataat tagatgtcct
     8581 tttttaggag ggcttagttt tttgtaccca gtttaagaat acctttatca tgtgattcta
     8641 aagtatccag agaatatctg tatgctttgt atacctatgg ttatgcataa aaatcccagt
     8701 gataaaagta tttatcactg ggatttttat gcccttttgg gtttttgaat ggaggaaaat
     8761 cacatgaaaa ttattaatat tggagtttta gctcatgttg atgc
//
LOCUS       DACDAF010000103         8746 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.106, whole genome shotgun sequence.
ACCESSION   DACDAF010000103 DACDAF010000000
VERSION     DACDAF010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8746)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8746)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8746
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.106"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(25..318)
                     /locus_tag="IVZ69_002396"
     CDS             complement(25..318)
                     /locus_tag="IVZ69_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HAP8184431.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(346..1011)
                     /locus_tag="IVZ69_002397"
     CDS             complement(346..1011)
                     /locus_tag="IVZ69_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HAP8184432.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1151..1783)
                     /locus_tag="IVZ69_002398"
     CDS             complement(1151..1783)
                     /locus_tag="IVZ69_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8184433.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1790..2857)
                     /locus_tag="IVZ69_002399"
     CDS             complement(1790..2857)
                     /locus_tag="IVZ69_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HAP8184434.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2854..3585)
                     /locus_tag="IVZ69_002400"
     CDS             complement(2854..3585)
                     /locus_tag="IVZ69_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HAP8184435.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3754..4233)
                     /gene="greA"
                     /locus_tag="IVZ69_002401"
     CDS             complement(3754..4233)
                     /gene="greA"
                     /locus_tag="IVZ69_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HAP8184436.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4369..5544)
                     /gene="mltG"
                     /locus_tag="IVZ69_002402"
     CDS             complement(4369..5544)
                     /gene="mltG"
                     /locus_tag="IVZ69_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HAP8184437.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5748..6917
                     /locus_tag="IVZ69_002403"
     CDS             5748..6917
                     /locus_tag="IVZ69_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HAP8184438.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7184..8098)
                     /locus_tag="IVZ69_002404"
     CDS             complement(7184..8098)
                     /locus_tag="IVZ69_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184439.1"
                     /translation="MIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDSELLSFGIG
                     LTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLNIIQAPWRF
                     MIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNMVKEMNFQG
                     TYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPNKDEITFTF
                     KSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTIRYSYTFFS
                     KISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(8156..8746)
                     /locus_tag="IVZ69_002405"
                     /pseudo
     CDS             complement(8156..8746)
                     /locus_tag="IVZ69_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177099.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2762 a         1680 c         1315 g         2989 t
ORIGIN      
        1 aaaattgtgt caccctctct ttttttattg ttttttaaag tgataggttg gctcctccag
       61 gttgggatca taatcaacaa gtaaatcata tcctttaaag aaccattcat ctgcttcctc
      121 gataaaaaaa agtgtcccat caatttccac tttctttaca ggatgttctg gctgttcaac
      181 tgacattcca atcgaaaaac catcatgaac ctctgttttg ccgtagactt ttccaaaaaa
      241 acgtattccg taagtttctg gcagatcaat ttctgagtca aaccactttt gtgcttttgg
      301 cgttaccgtt aatttcatcc caacaaccta ctttctcttt tctttctatt gattcatctt
      361 atcgtctaga atatccacat cgcctgtctc tccaataacc agtagattat cattttcacg
      421 aacatattca tctgctgcag gagaagcgat aaccgtttga tctactcttc gtatggcgac
      481 tactgttaag tcaaaacgtt gcctgaaatt taattcagct aatgttttgt tgaaaaattt
      541 aggattggag actcggattt ctgctaaaga atatttatct gacaactcta ggtaatctaa
      601 aatattcttt gacactaaat tatgcgcaat ccttattccc atgtctcgct cgggatggac
      661 gacgcgatca gctccgatct tttcaagtac tctggcatga tactcatttt gggcttttgc
      721 taaaatattt ggtacgccca tttcctttac catcagagta actaagatac tggcttgaat
      781 atcttctcca atagcgacaa ttacatgatc gaaatttctt atgcctaatg atcgaagtgt
      841 catttcatcc tgtgcatttg ccacaacagc atgagtggct atattcatat attcattgac
      901 ccgatcttca ttactatcaa tagccagtac ttcttgacca gcttcgatca gtgttcggca
      961 gatacttccg ccaaatcgtc caagacctac aattgcaaaa ttttgtttca ccgttttcct
     1021 cctttagtat cttcttttct cagtataaca aagcctttac aaaaacaaaa gcaagcatca
     1081 ttattgtaaa aaagccaaga aaaataatag ttattttctc agcttttgat tatcctcttt
     1141 atcatcgttt ttatttcacc aaaccatgtt tgaatgcata gatagcggct tgtgtacggt
     1201 cttccacttc tagcttagcc aatatattgg aaacatgtgt ttttactgtt ttcagtgtaa
     1261 taaacaattc gtccgctatt tcctgattac tttttccttc agaaatcagc attaaaattt
     1321 cattttcccg attcgttagt tcttcatgta atacaggctc atttcgccga ctcatttttt
     1381 ccatcatttt tgttgtcact tctggttcta atactcgctc gccacgttgc gttgccctta
     1441 tagcatcagc aatttcatgt gcggtagagg tcttcaacaa ataccctgct gcacctgctt
     1501 caatggcagg ataaactttt tcgtcatcaa taaaactggt tacgataatg attttagctt
     1561 ctggccaatc ttttaagatt gcttttgttg attcgatacc atccatttct tccatgacta
     1621 agtccattaa aatgacgtcc ggtcgaagtg tcatcgcctt ctcatagcct tgtcgtccat
     1681 tttcagcttc tccaattact tcaatgtctt cttgaataga taaataagaa gagacgccta
     1741 agcgcaccat ttcatggtca tctactaata aaacttttat catccttatc tatgcctcct
     1801 tcatcaaagg gaccttgatt tctacacttg taccttgacc tttaaaacta atgattttta
     1861 ctgttccacc aataccagct actcgttctt tgatattgtt caatccataa cttcccgttt
     1921 tcgtttcatt catattaaac cctgttccgt cgtcaataat acgtaacaaa agattattgt
     1981 ctattttgtg caaatatacc tctaattcat tggctttagc atgtcttaat gtatttgata
     2041 acaattcttg aacgattcgg aacaagtgat cctcaatgga actagatagt tttacatctt
     2101 ctacatccca tttcagcgaa atctggattt tattttgcaa ttccttcaat aactgctcga
     2161 taccttgctt taaacttttc tcttctaaat tgactggacg tagatgaaga agcagcgcac
     2221 gcatctcaga ctgggaagcg ttgatgatct ctgctaccat tttcaactgc ttgcgaaaca
     2281 tttctggtgt ctcgcttttt tctgcttgct ccgtcaatgc cgacatcatc atcattgctg
     2341 caaacaattg ttgcgaaact gaatcatgca gctcacgggc taatcgatgt ctttctaatt
     2401 ctaaaatttc ttctttggtt tgtccatcta catattgggg acggctcgtt acaatttgta
     2461 attcactaga tacttcaatc attttttctt ttatcttagt gatttcctta tcaatatctt
     2521 tgatgtataa atcgtccgat gcacttggga tcggaagaag caacaatttg gattcataat
     2581 tgccagaaga aagtgcacgc agcttttctt cgattttccc gtattttgtc ttttgaataa
     2641 gtgataataa tagaaagaca attaatccta cacctaagga aatggctaac aaatggaaga
     2701 taagcggaac atataataaa cgtgcacgca gtaattctcc ccaccaatga ctttgattgc
     2761 tggcataaaa ataagtgaaa agtgaaaata gaataataag gaaagccgca atccccgaat
     2821 aaacagctag catcgctctg gatatttttc ccatcatatt cgtatcacct cgacatctcc
     2881 aatcaaggta ttagtaataa tcttcaatct acgagggttt tcatcataat cactgctgta
     2941 gattttgatt tgttcatttt tcaaagaaaa ttgctcttct tcaaacaaga catttcctac
     3001 taatgtcgca tgctctaatc ggatggctac gcccaaaggt actaagatcc gtgttctgcc
     3061 tatccctttt cttacaatca caatattatc atcttttggc aaaagcgtat tgcccaaatc
     3121 tatgatagta tcaccagaaa tgacggcgat gttgatatcg tcccattcat agacgtcgtt
     3181 tccaatacgt tggttaccga ataattgctg tcttttccgc tcattattat gtgtttttaa
     3241 ttgctctgtt tggatcatca tgatctgttt ctttcgccaa aaagcatttt tggttaaatc
     3301 tatccctgaa atctctacac ctttcagacc aataaataaa acggcaaata cagccatcat
     3361 ccataaagca ggactgttga ctaagctaaa aaaaatgacc aaacttccta atatcaattg
     3421 aaaattttga aatttagtac gaggatgttt gcgcatagct agatatatat tgaaaatacc
     3481 gaatatcact aaaagcaaaa gtccagtatt gtttacgatt tgccaaacag caaataacag
     3541 cagtagtgct tcaactacca caaaaaaacg ccaagaacta ttcatcgctc tttctccctc
     3601 ctgacacatt ctcatttcat catacctatt tttttaactg ttggctatag gactttagat
     3661 gtaagatcgt ttgttgaaat ctaaaataca caaagagaaa aagatctaga gtgtatcatc
     3721 agtaagatga actctctaga tctttcagtc agactacgct tgttctactt tgacgatttt
     3781 aactaacata tcgccacctg gagtagcaat agttacttca tcatttttac gtttgccaat
     3841 caatgcttgc gcaataggag aatcattgga aattttgcca gaaaacggat ctgcttcagc
     3901 gcttccgaca atcgtgtact cttcttcttc tccatctggt agttcgatga atgtaactgt
     3961 tttaccaatt gatacctcat ctgcatctac accgtcgtta tcgatgattt gagcaaaacg
     4021 aatcatattt tcaattgttg tgattcttcc ttcaacaaat gcttgttcat ctttcgctga
     4081 ttcatattca gagttttcgg aaagatctcc gaaaccgcgg gcaattttga ttcgttcaat
     4141 gatttctccg cgtttgactg tttttagttc ttctaattct ttttctaatt tttctttacc
     4201 ttctagagtc attggataaa ctttctctac catgtgtaac gtctcctttt ttcgataaaa
     4261 taccgcaaaa ggtaatcttt tgaggaatat agtccaaaaa agattaccac gcttttcttc
     4321 aaatgtaaat gtttttctaa aaatgatcaa tgtctagagc ctgtttttct aagaattatt
     4381 tacatatttt tccactaatt ccatatgttc ttcataagtt ttagcgaaat aaacatttcc
     4441 agtgctcgta tctgctacga aataataata gtcattttct gctggttcta atactgcctt
     4501 gattgcctct tcgcttggat tgtcaaaagg tccaggtcca tagccggtat tggtatacaa
     4561 attatatggt gaatctacag ctgtatcttc atacgtcact aattctttgt gttcacctaa
     4621 tgcgtataaa acagagatat ctgactgaag tggcatattt gctttgattc ggttaaagaa
     4681 gacttgtgca atgtttttac gatcattttc ttttacgcct tctttttcaa ctagagaagc
     4741 tagagttaaa acttcttgta cagtcaaatt tttctgcttg atagctgaat aatagttttg
     4801 catgaccgta ttcgtcttgt tcaccatttc aatcactaga tccttaagcg aagtactcgt
     4861 gtaataatca tatgtggctg ggaataagta accttccaaa cggtattttg tgttctcagc
     4921 tttagatgca ctttccaaca gttctgggaa tttttggtgc aactcgttaa agaaagtctc
     4981 atcattcact aaatctaaaa attctttctt gtctttacca gttaccttcg ctacccgttc
     5041 agcaatctga tcgatatcgt acccttctgg aatggcaatt ttcccatctg caacttttgt
     5101 tggctcagaa gtaccgcctt cttgcaactg tttgccaatc tcgtcaagag tcatattagg
     5161 cgctaactga taatagccag cttgaaagcc agttaaattt ttaaattttg tataataatt
     5221 gaaaacaatc ccgcttttaa taatattgtc cttctccaaa atctcaccaa tctgcttgtt
     5281 agaagagcca ctcgggatct cgacttggac taattggtca tctgatttat ctaaaggctt
     5341 caacccgcta tctacataac gatacacggt aaatccaaga aatccgccaa taatcaataa
     5401 tgtaagagca atcactaaaa tgatcttcct cacaatctta tcttcttttt tacgcagatt
     5461 tctccgcttg tcgattatat ctgctgtagc tgccttactg gcttcttttt tatctttact
     5521 tgggtgttgt ttgtttcctg acaaaacaac tcctccttac tatcaagttc gtaactttat
     5581 tcattataca tgatatttga attggcgtga atgattttat ttaaatattc tatcaaaaat
     5641 gtaagtagta aatccattac tataagatta aaataaatgt tatcaagata caagctattt
     5701 tagctttatt ctttctgtaa aaaagaaagg agactaaata aactattatg aaaaaaggaa
     5761 aacatgctaa aaaaagaaaa tattcatttt taatgatcgt tgtcgtgttg tttagcctta
     5821 gtgcgttctc tacaggaact attcttggat ggcaatttta caataatgaa cactctcaga
     5881 tagttgccca tgctcaatca gctcaaaaaa agttgatact gactaccaat gaacaacagc
     5941 tcgttgaaaa aatcgatcaa ctattaagaa aaaatgatta tattggctca atttacgtaa
     6001 agaaaaataa tcgcatcatc atggaaaaag gctatggcta tgcgaataaa ctcacgcaac
     6061 aaccaaatga tccttctctt tattatcaga ttggttcggt tcaaaaagca ttgactactc
     6121 ttttgatttt aaaacaagtc gagcgtgggc acctttcttt agatactaag ctggctcaat
     6181 tctatccaca aattgctggc agccagcaaa ttactatccg tgacttgctg tatatgcgct
     6241 caggcttgca ccgaactgct tctccaacca taccgatgac tgatgaagaa gtcgttcaat
     6301 ttgcgattca gcacttaaaa tttacagatt atcagacctc tcattatgat tcattgaact
     6361 ttaccatatt gactggaatt ttgatcaaat taacaaatca accgtatgaa aaattattga
     6421 ccgatgatat catcgaacct ttaggattac agcatacaaa attttatgac caagtcaaaa
     6481 attcatccaa tcatgcacta tcctatcaaa tgtctaaaga ggatgattac tttaaaccac
     6541 tgacagaatc tgaaacagag atccataacg aattagggac tggtaatatc agtatgtccg
     6601 tctatgattt aaatacgctg tttacacaag ttttatctgg aaaactagtt tccaaagact
     6661 tactcttctc attatggcgt gaaaatgcga atggacatcc atatagtggt ggggtatata
     6721 gcggagataa ttatatcctg tcgcaaggaa atatcgactc ttttgataca tctgctatat
     6781 ttagcaaaga ttcacaggat gctatcatca tggaaagcaa tataaaagct gacaaaacta
     6841 tcaaactgcc tactgctgat ctaagaaacc aaatctatga cctgatggaa ggaactacta
     6901 agttggcaaa tagctgatat gatgaaaaga tagcaaatac tacttctttg aatagcattt
     6961 gcttaaaaaa agtactcgac taaacgtagg aaagagtgtg ggacaaatct aaaaatcaat
     7021 ttttgctaca gactttaatt ccaaataaac agaacagaaa gaggtgttct tctttctgtt
     7081 ctgtccaaat tattctaaga tttctcttta ccaacattat ttgacaaagg gcctattaaa
     7141 tctaaaatag tatctttaga ttgctaaaat atgtgctagc aaatcattca tggcttgttc
     7201 ttatttttaa ttttatgcaa taaaaaagaa gaacaattag cgtgattata gaaataaata
     7261 atgagatttt agaaaaaaat gtgtatgaat acctgattgt tactttattt attccacttt
     7321 cactttttac tgtaacaaaa ggacctcctt gttttagtac tgtagcattt tttgaattaa
     7381 cagtaaccgt taatccttta taccggaata caggtaaaac tattgttttg ccttttgaag
     7441 atttaaacgt aaatgtaatt tcatctttat ttggagaaaa gctactataa ataacttgac
     7501 catcttctgt aacttgatgg tttttcaaaa gcaattgatc ttttttatag cctataggta
     7561 cataatcaaa attctcaaat tcttcaagtt tattttccat ttgttcatta gaataagttc
     7621 cttgaaaatt catttctttc accatgttaa ctactgatga ataatttaaa attgaaatag
     7681 ctaatattaa taatagtata aaatttcttc tccttgtata agaaaatttt tccaactgtg
     7741 gagaaataaa tagagatact gaaaaagata tgaacaatgt tgaaaatatc ataaaacgcc
     7801 aaggagcttg aataatattt aaaggagtat tttgtaaggc aaaccatgga aatatttttg
     7861 tacaaagtag aatagatatt atacccatta tataagtgat tttagataag attcctaatt
     7921 ttttaaagtt aaatgttagt ataattaaac aaataagcaa agttaagcca ataccaaatg
     7981 atagtaattc tgaatctata cttccaatca aaaactcttt acccagataa attgctcttt
     8041 tttgtaatat atccacataa ggtctattca gatcttgata caatgtctgc tcaatcatag
     8101 gacctataaa cgctagtgaa agaagtaaag taactatagc agcttttatt aatttaataa
     8161 ttaagaagat ttctattttc tttttccgat aaaattgaat aattaaagca attataatca
     8221 ttaccatagt catagctaca gaaagaacat gagtgtaaat taataaagtc atgctaatcg
     8281 ccaacataac ccaagattct ttttttgagt cgtaaagctt tataaacccg agtaaaataa
     8341 gaggaagtat tgacattgcg agtaattccc ccattgcccc tcgaagaaat atttctacac
     8401 tcctaaaaga agatgttgta tatataatag cgaaaaagga gctagtaaca tgttttttgg
     8461 taatttcata cattacataa tgacatataa atagagtaat gagcgtaaca atataaagaa
     8521 aaaggttata gcctattgct aaattagtaa acttgatcaa taaaaataaa ggatatagag
     8581 ttaaccatgg gtaaaaatta tttacttgca tgccatatga tctaaacgtt tcaaaattaa
     8641 taggggagct aaaaatagat tctaaactta acgcacgatt aatgtgaaat gccgtatcat
     8701 aaaagccaaa tatttccatg tttttaaatg ctggaaataa atataa
//
LOCUS       DACDAF010000104         8594 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.107, whole genome shotgun sequence.
ACCESSION   DACDAF010000104 DACDAF010000000
VERSION     DACDAF010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.107"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            82..561
                     /locus_tag="IVZ69_002406"
     CDS             82..561
                     /locus_tag="IVZ69_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HAP8184440.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            778..1869
                     /gene="phnW"
                     /locus_tag="IVZ69_002407"
     CDS             778..1869
                     /gene="phnW"
                     /locus_tag="IVZ69_002407"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HAP8184441.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            1862..2647
                     /locus_tag="IVZ69_002408"
     CDS             1862..2647
                     /locus_tag="IVZ69_002408"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HAP8184442.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(2993..4684)
                     /locus_tag="IVZ69_002409"
     CDS             complement(2993..4684)
                     /locus_tag="IVZ69_002409"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HAP8184443.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(5106..6053)
                     /gene="arcC"
                     /locus_tag="IVZ69_002410"
     CDS             complement(5106..6053)
                     /gene="arcC"
                     /locus_tag="IVZ69_002410"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HAP8184444.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(6168..7187)
                     /gene="argF"
                     /locus_tag="IVZ69_002411"
     CDS             complement(6168..7187)
                     /gene="argF"
                     /locus_tag="IVZ69_002411"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HAP8184445.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(7278..8507)
                     /gene="arcA"
                     /locus_tag="IVZ69_002412"
     CDS             complement(7278..8507)
                     /gene="arcA"
                     /locus_tag="IVZ69_002412"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HAP8184446.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         2470 a         1748 c         1584 g         2792 t
ORIGIN      
        1 gtataaaaga cgaatattat tgggcaatcc ttcttttttt tgttatgata catgtgaaat
       61 ctttcgtaaa ggagaaagaa aatgcgcaaa gctcaaagac atttgctgat taaacaagtc
      121 attgaagaat tcccgatccg tacgcaagaa gaactattaa acaaacttgg gcattatggc
      181 gttaccgcca cgcaggcaac gatttctcga gatatccgtg atctaaaaat cgtgaaggca
      241 cctgatgaaa atggcgtttc ccgcttcgta ttgtttcgcg aaaaaggaac tcctgagact
      301 aggactgagg aagaggatcg gctggttcaa atgattgaag acattgtatt gaaagtcgaa
      361 cgagtccact ttttgacgat cgtcaatacc ttgccagaca atgctcattt atttgcatct
      421 gttttagatg agatcaaacc tccctctatt gtcagtacaa ttgctggatt cgatacgatc
      481 atggtcatct cggaaaatga ggaggacgca aaacgagtag aagaatttct tcaccatcca
      541 actgaagtat cactttttta atcagagcac gtattcctaa tatggaatgc gtgttttttt
      601 attttcaata ttttccttat taaataaacc tttacactct ttacaaaaat acatcatttt
      661 ttattcaatt ttttcaacac cttgattgaa tcacaataat catcatttat attggatgtt
      721 aacaagagca gcttcttgct ctttgtgtat ttcaaaaaag aaatgaaagg aaatcatatg
      781 tataaattat taactcctgg accattgacg acttctgaaa cagtgaaaaa tgctatgctg
      841 atcgatcatt gtacttggga tcaagaatac aaagaaatta cacaatggat aagaaaaaaa
      901 ttattggatc ttgctcaagt atcggaagga atatacacaa cggtcttaat gcaaggtagc
      961 ggctcctttg gggtagaatc ggtattaagt tctgtgatca ggccagaaga tactgtactg
     1021 atttgttcaa acggcgcata tggacaacga atgatcaaca tgtgcgaatg tctgaaactg
     1081 aactataccg tttatgaggt atcggaacat caaatcctcc aagctcatgt gattacacag
     1141 ctgattgaag agaatccctc tatctccgca ctagcaatgg tccatagcga gactacttcc
     1201 ggtattttga ataatttgga agagattgct gctgtcacac aagaaaaaga tcttttgttt
     1261 atagtggacg cgatgtcaag ctttggtggg ataccgattc gtgtagccga actagggatt
     1321 gattttttga tttccagctc aaacaaatgt attcaaggtg ttccaggctt ttcttttgta
     1381 cttgctaata aagcggaact agaaaagcga aaaaatgtga gtcgaagttt gtcacttgat
     1441 ctatatgacc agtaccgcgt gatggaaaac gagaatggca aatggcgttt cacttcccct
     1501 acccatacgg ttttggcttt tcaacaagcg ctgaaggaac tagaggcaga aggaggaatc
     1561 gaaactcgat attcacgtta tctcgccaat aatcatgtac tacgacaaaa aatgacagag
     1621 atggggttcc agcctttcat tcaagaatat caggggccat tcatcacctc ttttctttac
     1681 cctaaggact ggcgatttga ttttaatcat ttttatcagt atttaaagca aaacggattt
     1741 gtgatctatc ccgggaaaat cagcgatcat gaatgttttc gtatcggaaa tattggcgag
     1801 atctatccgg aagatatttt ggaactgaca gcaattatca aagactataa ggagaacgtt
     1861 aatgattaaa actgtaattt ttgattgggc aggaacaact gtggactttg gctgtatggc
     1921 tcctgtccac gcttttagaa atgcttttct agaaaaagga atccaactga ctgacaaaga
     1981 aatccgcgaa ccgatgggaa aattaaaatg ggatcatatc caacagcttc tttccctccc
     2041 ttctgtcaaa aaacaatgga tagctattta tggacaacta cctcaggaaa aagaggtgga
     2101 ggaattgtat caacaatttg aacattatct gtttaaagat ttggtcaagc attctacctt
     2161 gaaacccgac acattggaaa cgatcgaacg gttgagaaac gctgggatca atattggttc
     2221 cacgactgga tttactgctc ctatgatgac aatcgtagca gaaaccgcaa aaaaagaagg
     2281 gtattcacca gacttcatgg caacttctga agacgtcgaa gggtatggtc gaccgtttcc
     2341 ttatatgatc cataaaaaca tgcagtactt caaaaacaag tcggttgatg aagtaatcaa
     2401 agtcggagat acggtctcag atatccagga agggaaaaat gccggagtgt tgacagtagg
     2461 tgtaattgaa ggtagttcgc taatggggat ttcttatgat gagtaccaaa aattagagat
     2521 ggggaaaaaa gatcgtttaa aacagtctgt tgctcttaga ttccaacaag ctggcgctga
     2581 tatttgtgta aacaatttaa aagagttaac agaatacatt ttgtacgctg acaagaatcc
     2641 agaatgactt ttatacaaaa tcagaggtcg tgaaaaagct gtactgcatc aagtaataag
     2701 aacagccaaa caaaaatagc tcctcatatt tttcgtttgg ttaggcttat taccgcagat
     2761 gcaagctttt gaacaccgtt tattcgaaaa aaaaagggag ctgtgacacg acttttgtca
     2821 cagtcccctt atttacaaac aaacagtgtt taagagacaa cctctccact aaacggtgtt
     2881 cattcagctg actctcggta tttgctcaaa aaacgataaa atttgaaaag ctattttctc
     2941 ttttgtttct ctaatactcg gatcagaacg ctgatttcac attctctttt tcttacatct
     3001 tatctggtgc atgaagtcct agcaaacgaa ggtcttcttt caataataca gtcactgcat
     3061 aaactagagc taagcgtgct tctttttgtt catcatcagc taaaatcttc gtatgagcat
     3121 agtatttgtt gaatgcttgt gctaatttga ttgcatgttt cgcaatcact gacggttcgt
     3181 atttttcccc agcagacaag accgtttcag ggtatttttg aactaattta accacttccc
     3241 agctggtatc gtcattcaat gcatagtctg ctgtttctga agggacaaat cctgcttttt
     3301 ccaacaggct gactgcacga gcatgtgtat attgcacata aggtccagtt tctccttcaa
     3361 atcgaacaac ttcttccagg ttaaagtcaa atgtattcag tcgatcgttt ttcaaatcgt
     3421 ggaaaatgac tgccccaacc ccaacttgtt tagctacagc atctttgttt tccaaatcag
     3481 ggtttttctc gctgatttgt tctttagcag attggattgc ttcatttaat acttcttcta
     3541 ataagacgat ctttccttta cgagttgata attttttacc accttgcgtg atcaaaccaa
     3601 atggaatatg gcgcatatcg tcagaccagt caaagcccat ttccttcaag acagctttca
     3661 actgtttaaa atgatagctt tgttcattcc ctactacata tagagattgt ttgaagtcgt
     3721 aagtacgttt acggtacaat gcagcagcta agtcacgtgt aatgtatagt gtcgcaccgt
     3781 ctgacttctt aatcaacgct ggattcaggt cataagcaga taggtcaacg atctctgcac
     3841 ctttatcctc gttcagcaaa tgtttttctt ctaaaagttt gacgatttca tccatcttgt
     3901 cattgtagaa agcttcaccg ttcaacgaat cgaaacgtac ttccagcaga tcatagattt
     3961 tattgaattc tttcatcgat tcatcacgga accattgcca taattgaata gcctcttcat
     4021 cgccttcttc cagacgtttg aaccaagcac gagcttcttc atttaattct ggttctgttt
     4081 cagctacttc atggaattgg acatataaac gaagcaattc attgattggt tctgctttaa
     4141 cagcttcttc tgtaccccat tttttgtaag cgacgatcag ttttccaaac tgtgttcccc
     4201 agtcacctaa atggttgatg cggattggct gataaccgat tttttccata atgaaaccga
     4261 tcgaattacc gataactgtc gaacgcaaat gtcccattga gattggtttg gcaatattag
     4321 gagaagacat gtcgattggt actgttcctt gattcccgat attgctatcc ccataatgtt
     4381 ctttttcttt cactactgtt tgcaaaactt ttttgctgat aagttcttta ttcatgaaaa
     4441 agttcaagta aggtccgaca acttcgattt tttcaaagtt ggcagaatcg attttttctg
     4501 ctaaatctgc agcgatttgc tgtggcgctt ttcggtaaac ttttgctaat gaaaaggctg
     4561 gaaatgcaac atctccgtgt tcagctgatt ttggattttc tagtaattgt tcgacttgtt
     4621 ccagtgttaa atcatctttg acagcgtcat agacagcttt tgcgacaaga tctttattat
     4681 tcatctttat tcctcctaaa gtgctccctt gattgttaaa caaaaaaaat ctctagcgac
     4741 ggcatactta gtatgccatc actagagacg agatttcccg cggtaccact ccaattgtcc
     4801 taaaaaagga ccagctccat ctgatatcgg tagacgaccg tctgtttaaa acagaattct
     4861 ccaagtgcgc ttcgttgtat cttcttcatt cggcttccac cacttccgaa ttcgctagcc
     4921 aagaatgata caagtactct cttgttcaac aaatcttagt cttattaaac tttcttgaat
     4981 tatatcagaa aaaaaaacga aaggctagtc gtttctgata aaaaaacaat ccagatggcc
     5041 taaaggagaa gaaataccac ctggatagct ataaatcatt tcgtaaatac gaaagactta
     5101 acaaattaat cagctacgat aatcgttcct tcttcagaag ctaaaagatt ctcgatattt
     5161 tctaaagaag tgatgattgc cttagcgttt ggttttgctt caacaaatgc aatagctgcc
     5221 tctactttcg gaagcatgct tcctggagca aattgctttt catcaatgta ttgtttcatt
     5281 tctgaaacag taacagtttc taatttcttt tgatctggtt tttggtaatt gacatacaca
     5341 ttgtctactc ctgtcaatac gatcagcaaa tccgcatcga tgatttcggc taatttttct
     5401 gaagcaaaat ctttatcgat tacggcttct cgtccttcta atccagtagc tgtttctaca
     5461 acaggaatcc caccgccacc aacagagact gtgataactc cttgatcgac cagcgtttcg
     5521 atgacacgtg cttctttaat cgagatgggt ttaggggaag cgactacttt tctccatcca
     5581 cgtccagcat cttctttgaa tgtcacagtg gagtcagcat tcatttgttc tttggcttct
     5641 tcttccgtgt agaatggacc gactggttta cttggatttt tgaatgaagg atcattttca
     5701 tccacaataa cttgagtgac taaagaaacc acatctttat cgatcccttt ttccttcagt
     5761 acttcgccca tggcattttg taaccagtaa ccgatagatc cttctgtcat tgcaacacat
     5821 gtatctaaag gcattgccgg tgttttctca gaatcagcag cttgctgctg aatcaatagg
     5881 ttaccgactt gcggaccatt tccgtgggag atgatcaatt catctccttg ttcgataaat
     5941 ttcactaaat actttgctgt ttccattaac gcttcttgtt gggcttttgc acttgcatcc
     6001 gtagacaaga ttgcattacc ccctaaagcg acaactactt ttcgtttggc catttcattc
     6061 gtcctttctt cagttctacc gaattttcta gataacaaaa cgagccagcg ttttgtgatt
     6121 ttccctcaat gctgactcgt tttttcgtga gatgaatgtg gttatgctta aacgcgaggg
     6181 ataaacaagt tacctaatgt tgctgccatg atcgctttga ttgagtgcat acgattttct
     6241 gcttggtcaa attgacgagc atatttgctg cggaagactt catctgttac ttccatttca
     6301 gtgatgccaa agcgttcttt catttgttca ccgtaaacag tgtttgtatc atggaaagct
     6361 ggcaagcagt gcaagaagat caaacgatct gtgttgtgtg ttttttctac catttccata
     6421 ttgatttggt aaggtttcaa caatttgata cgttcttcga atttatcttc ttcacccatt
     6481 gatacccata catcagaata aaggacgtct gctccgtcta cacctttatc aacatcgtcg
     6541 gtaatcatca attgtgcacc ggatttttca gcaaagcctt ctgccatttt gacgatttct
     6601 tcttcaggtt gtaattcttt tggtgcaacg atacgcatat tcgctcctaa aattgcacct
     6661 gtgactaata aagagttagc catattgttt cgaccatctc cgcagtaagc aacagtgata
     6721 ccttctactg ttccaaagtt ttcttggata gttaaaaagt cagcgatcat ttgtgttgga
     6781 tgccattcat cagtcaagcc attccaaact ggaacaccag agaattctgc tagttcctct
     6841 accatttttt gactgaatcc acggaattcg attccatcaa acatacgacc tagtacttta
     6901 gctgtatctt ctgtggattc ttttttacct aattggatat catttgcacc tagatattca
     6961 ggatgtgcac ctagatcgat cgctgcagta gtaaatgcag aacgagtacg tgtagatgtt
     7021 ttttcaaata aaagcgcaat attttttcct tctagatagt gatgtgggat accacgtttt
     7081 ttcaagtctt tcaagtgttc tgaaaaatcg atcaaatatt gtaattcttc ttttgtaaag
     7141 tctttttctg ctaataagct tcttccttgg aatactgatt ctttcatatt aaacattctc
     7201 ctttagattg tttttattta agattaaaga ggaaatcccg acggcagctg acagtaagac
     7261 cgccgtcagg aaacaaatta cttcaagtct tcacggacaa gtggttggct catgcagcgt
     7321 ggaccaccac ggcctcgtga caattcactt gaattgattt ctaacacttt gatgccatag
     7381 ctacgaagca attcgttcga tacataattt cggttataag tgactacaac acctggagcg
     7441 attgccaatg tgtttgatcc atcattccat tgttctcgag gtgcaacgat ctcatctcca
     7501 ttaccagttg ggatcagtac aagatcatct aatccaagag cagctttcat cgtttcgtgt
     7561 aagttatctg aatgagtaat cttgatatca tcaccatctg gttcgattgt aaagacatcc
     7621 atcttaccgt ctttactttg aattgctgga tggatagtga atttatcgtg atctaccatt
     7681 gtaaatacgg tatccaaatg catcattgca cggttgtttg gaattttgat tgctaacact
     7741 ttttcaaatc ctgaattttt tgcgaatagg tggcgtgcta atttttctaa agctttcgca
     7801 ttagttcgtt gagaaatccc aacagctact actttatcgc ttaagatcaa ttcgtctccg
     7861 ccttcgatat gatctggatt ttcacgatcc aaccatactt cgattccttt atttgcaaat
     7921 cttggatgat gtttcaaaat atattctgta aacatcgatt cacgacgacg tgcttcaaaa
     7981 gtcatcttat tgactgtcat cccatttccc attgatgcgg aagggtcgcg tgtaaagtac
     8041 aagtttggca ttgggtccat gtaaaatgga tagtcatcgt ctgctgacag atcgtataga
     8101 ctgctagaac gtacttcaat atcttttgta cgaaccccag ccatgatttt atctaccatt
     8161 tcttgcgttt ccattgatag aaggaactca tgaagaccct ctcttacagc attcgatgca
     8221 atatgagatt catccaacat tttattcaag aattgttctt tgacattgcc tgcgtcaatc
     8281 gcttctgccg ctaatttttc caagtaaaga gtctcgacgc cttcattttg caatgtcttt
     8341 gcaaagttgt catgttcttc ttgagcaatc ggaagatatg gaatatcatc gaacaacaga
     8401 cgatccataa tatctggtgt caaattttcc acttcttgtc caggcctttt cagtaaaact
     8461 gtctttaatt tccctatttc agagaaaacg tgaataggtt tatccatgtt gtgttgcctc
     8521 cttctttttg attacatgta taggatatcc tccttttgta atcactttca taattttgtc
     8581 tcattcaaaa tgag
//
LOCUS       DACDAF010000105         8435 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.108, whole genome shotgun sequence.
ACCESSION   DACDAF010000105 DACDAF010000000
VERSION     DACDAF010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8435
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.108"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            115..2724
                     /gene="clpB"
                     /locus_tag="IVZ69_002413"
     CDS             115..2724
                     /gene="clpB"
                     /locus_tag="IVZ69_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HAP8184447.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(2875..3546)
                     /locus_tag="IVZ69_002414"
     CDS             complement(2875..3546)
                     /locus_tag="IVZ69_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184448.1"
                     /translation="MIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGITFIVES
                     LLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWDKILHA
                     VSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLCDQFLG
                     MNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFESYKLE
                     KVKNT"
     gene            complement(3539..4033)
                     /locus_tag="IVZ69_002415"
     CDS             complement(3539..4033)
                     /locus_tag="IVZ69_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HAP8184449.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(4053..5273)
                     /locus_tag="IVZ69_002416"
     CDS             complement(4053..5273)
                     /locus_tag="IVZ69_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8184450.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            5420..7255
                     /gene="lepA"
                     /locus_tag="IVZ69_002417"
     CDS             5420..7255
                     /gene="lepA"
                     /locus_tag="IVZ69_002417"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HAP8184451.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEDEPKK"
     gene            complement(7349..8431)
                     /locus_tag="IVZ69_002418"
     CDS             complement(7349..8431)
                     /locus_tag="IVZ69_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017414133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8184452.1"
                     /translation="MNDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTDT
                     RVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINAE
                     FKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKIIS
                     LEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVKN
                     DGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKEDG
                     ELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISIT
                     MDTYSHVTDKMRNETVDIMENLRKNS"
BASE COUNT         2712 a         1614 c         1696 g         2413 t
ORIGIN      
        1 aaagtcaaaa aactatgtgt atattttgac caaaattgac caaagcgata taatagtttt
       61 tgtaaagatc aaagaaataa gtgatcttac ctttaattag gagggtatac ctgtatgaat
      121 attgagaaaa tgactacgac gcttcaagaa gcgattgctg aagctcaaca gattgcggtc
      181 actcgaaaac atcaagatat cgacattgcc catgtatgga aaatcttttt acaatctaat
      241 cattttggtc gaaatttcta tacggatgcc ggattggatg tcgaatcttt tgaacatgaa
      301 attgatcgtc tactggatga gtatccagtt gtttctggtg gaaacgtcca atatggacaa
      361 aacctcagcc agaatttctt tcgattattg aatgaagcag accaaatacg tgaaagcttc
      421 ggcgacgagt ttctttcaac ggaagtcgtt attttagcgt tgatgaaatt aaaaaattat
      481 ccgttaactg tttatttgaa taaaaacgga ttatctgaaa aagaattgcg taaaaacatc
      541 gaagagatga gaggaggaga aagagtgacc tcacaaaacc aagaagaaca atacaaagca
      601 ttagaaaaat acggcgttga tttagtacag caagtcaaaa gcggaaaaat ggatccaatc
      661 atcggtcgtg atgaagaaat ccgtgatgtc atccgtattc tttcacgaaa aacaaaaaat
      721 aatcctgttc tgataggaga acccggtgta gggaaaacgg caatcgttga agggcttgct
      781 caacgtatcg tacgcaaaga tgtgcctgaa aatttaaaag ataaaacgat tttttcatta
      841 gatatgggtg cattgatcgc tggagcaaaa ttccgtggtg aatttgaaga aagactaaaa
      901 gcagtcttga aagaagtcaa aaaaagtgat ggacgtatcc tcttgttcat cgatgaaatc
      961 cacaatatcg taggggcagg aaaaacagaa ggaagtatgg atgccggaaa tctgttgaaa
     1021 ccaatgcttg ctcgcggtga attacatttg atcggtgcca caactttaga tgagtaccgt
     1081 caatatatgg aaaaagacaa agcgttggaa cgtcgctttc aaaaggtatt agtcaaagaa
     1141 ccaacagtgg aagatacgat cagtattctg cgtggattaa aagaacgttt tgagatccac
     1201 catggtgtta acatccatga caacgcatta gtagcagcag ctactttatc tgaccgttat
     1261 attactgatc ggttcttacc ggacaaagca atcgatttga tcgatgaagc cagtgcaacg
     1321 attcgggtag aaatgaactc tatgccaacg gaattagatc aagttactag acgtttgatg
     1381 cagttggaaa tcgaagaagc tgcactgaaa aaagaatcag atgatgcaag taaaaaacgc
     1441 ttgaaaaatt tgcaagaaga attagctgaa cttcgtgaag aagcaaatgc gatgaagatg
     1501 cagtgggaaa cagaaaaaga agaagtcaat tctgtttcag caaaacgtgc tgaaatcgat
     1561 aaagcaaaac acgaattaga agatgcagaa aataactatg atttagaacg cgctgctgta
     1621 ttgcgtcatg gtacgatacc tcaattagaa aaagaattga aggaattaga agctaaagca
     1681 aaagacagcg agattaagat ggttcaagag tccgttaccg aaaatgagat tgctcaagtc
     1741 gttggcagat taacgggtat ccccgtaacg aaacttgtag aaggtgaacg agaaaaacta
     1801 attaaattga atgaaacact tcataaacga gtgattggtc aagatgaagc agttgatgcg
     1861 gtcagtgacg cggtaattcg ttcacgggct ggattgcaag acccaaatcg tcctctaggt
     1921 tctttccttt tcctaggacc aactggtgtc ggaaaaaccg aattagcgaa agcgttagct
     1981 gagaacttgt ttgactcaga agatcatatg gtacggatcg atatgagtga atatatggaa
     2041 aaacatgctg tgtctcgtct agtcggagct cctccaggct atgtaggtta cgaagaaggt
     2101 ggtcaattaa cggaagctgt cagacgaaat ccttatacaa tcgtcttgtt ggatgaaatc
     2161 gaaaaagcgc atcccgatgt cttcaatatc ttgttacaag tcctagatga cggacgcttg
     2221 actgattcaa aagggcgagt agtagatttc aaaaatacgg ttctgatcat gaccagcaat
     2281 atcggttcac agttactgct ggaaggcgtg actgctgatg gaacgattcc agaagcagtg
     2341 gctgaacaag tcaacacgct attacgtgga aacttcaaac cagaattctt gaaccgaatc
     2401 gacgacacga ttttatttac accattgagc ctagacaacg tgaaaggaat cgttgacaaa
     2461 atggtggcgc aattggcaca acgtctggaa catcaagaaa tcctgctgac aatcagtgat
     2521 gaagccaaaa cgtggattgc tgaaaatgct tatgaaccag catatggtgc aagaccattg
     2581 aaacgattta tcactaagga agtagaaaca ccactagcta aagaaatcgt tgcaggacat
     2641 gttatgccta aatcaaaagt aacgattact ttacttgatg gacaacttca tttcaaaaca
     2701 gaagagctag aagaaatcgt ctaatcttcc attgagacta taaaagaaaa aaggggtctg
     2761 acacaactag tgtcagacct ccttttttca aataaacagt gttccagaag tagtttcttc
     2821 gaaaaataag ccgaaatttc ttgaagctgc ccgcttctgt cacaacctct tttattaggt
     2881 atttttcact ttttctaatt tataactttc aaagtaacgc tcatcttttt tactttgaga
     2941 ccatgcaaac aatcccatta aggcagcacc tatcgtattt gtcagcaagt cgcccatcgt
     3001 atccatcaat gctgctcgtc cgacaaacag tgtgccatca gaagcagcaa aacgttgaag
     3061 attcatgcct aagaactggt cgcataagaa ttcccagaac tcccaaaaca cgccgcaaag
     3121 tccagcaaac gcaaagccga ataagaggaa caaccaagga ctggtttttg atatctcagc
     3181 atctttcatc aagtaaccaa tcaatccata gccaagagct gtcaggacca ttggactcac
     3241 cgcatgtaag attttgtccc aaaaagagat gatactgatc aaatgcatcc ctgtgcctaa
     3301 aaagacagag atgaacaaga aaaaccagta aaacaaaacg attgctgctg gtattttaag
     3361 tttgaaaact ttcaaaatga cttgtggcat gaaaatcaat gcaatcccta ataaagattc
     3421 cacgataaat gtgattcctt gagaagtcga atatttttgt gtgataaatt cataaaaatt
     3481 atagcagaca acgaatacac caaaagcaag taaagctatt tgcacctttt tgatttcttt
     3541 aatcactgaa agtccctcca tctaaaaatc tttttacttc tgaaagcaac tcaatttctg
     3601 aagaaaccac ttttccgttc aatttgatca aacctattgt atataagttc aggtagtgaa
     3661 attgattttc agctgtttct tgtagtgcag cgattttttt cgggtgggtt ccgccttgct
     3721 gtcgagtatc agtatataag ccgatcactg ggatgccttt cgcataagcc acaccgattt
     3781 ccgatgctac cccggcatcg atcgtcagcc catctagtaa agcaatcatt aaatcactag
     3841 ccaacacttt ttctgtgtca gcaagagcaa tcattcgact gtctgcataa gcagttttgt
     3901 cattgattgc ttcattttct tgaggaagat agatcgaaag ctcagaagag agctctctga
     3961 tttctttaac taactgttgg ttatataaca aatcactttt agcaaacatt ggtgcggcaa
     4021 aataaatttt catctaaaca tcatcctttt tatcaaaaat aatcgctaaa gtaagcttcc
     4081 atgtttggaa tgatacgctc tagtgacttc agtgtttctt catctgtttc taaccgttcg
     4141 attcttgcca aataagaagc acggcgataa ttcatcatca agcaagtcaa tgtttggata
     4201 tccagtcgaa cggattttcc tataggttca tttaagacac ggacttgtcc ctgttcatcc
     4261 catgttaaag cgaagacacc attattccaa ggagcgacag gatcttcaat gatgaaatga
     4321 aaagcatcag ctgttccaac aaacggaaac cgttgaagga attcttttac atcaacgatc
     4381 cgagccataa aatatggttc gatctgctct ttgatctgac tatcttcaat caaaaatgct
     4441 aaaggctcat ttttataaat atctccatgt acccagtaga tcatggaaaa atgtgcggaa
     4501 ataaagttcc ataagccatt tcgagcttct tgatcaagat agaacatttc ttttacgtga
     4561 aatatttctt cagctaccca gtagaacaga acacctcttg gttcatggtt gctatcgtag
     4621 tagacagcgg ctgtgcgctc atcttcattt tcgaaacgcc aatactcttc ccaatgaaaa
     4681 tcactgcgga ataaagcacc atggttttgt tgggcaaatt tgtcataaac ggaaaatacg
     4741 tctggatgat caactggtaa tcgctcaacc ataccactta ctgggatttg tttaggtagc
     4801 tgtgtatctc tgattttaaa ggaaagttta tcagacatga tttcccatcc tttacgccga
     4861 tagtagggga tactgtaagg atacaaataa gagatccatt gcttattctt gcgcatatta
     4921 tccaatgcaa cgataattag atcttgcatc aatccatggt tagcatattc tggataagtt
     4981 ccaactccag tcacaccacc cattttataa cgtgcaccgt gaatattgac ttcacaagga
     5041 tagatagcga tttgagagat cagtttattt tcgtggaacc atccgaacac tttcgatact
     5101 tccaaaatcg gttttttgga acggataaaa gctcgtttat tctcaaaccc gctttcctcg
     5161 atgtctgctt cagtcacttg gaacacatag gaaagcaatt cattgaattg atcgatatgt
     5221 tcttgagtga ccggttttaa ttcaagattt tctctaaaat ctttttgatc cattttttca
     5281 tctccattta ttagcttgat aacagtatag caaaattcta caaaaaaaac ttctatagct
     5341 gactaattaa aaactcttta aattactgct tttcgttggt ataatggaaa gtgctgatta
     5401 tatgaaaaga ggagacgcta tggatataaa gaaaatgaaa gaacgccaag agcagattcg
     5461 taatttttcg atcatcgctc atatcgacca tgggaaatct acattggccg atcgtatttt
     5521 agaaatgacg cacactgtga cgtctcgcga aatgcaagat cagctgttag actcgatgga
     5581 tttggaacgt gaacgtggaa tcacgattaa attaaatgct gtagaactca attacacagc
     5641 gaaaaatgga gaaacatata tctttcactt gattgacacc ccagggcacg tcgacttcac
     5701 ctatgaagtc tctcgaagcc ttgctgcctg tgagggtgcc gttttagtgg tcgatgcagc
     5761 acaaggaatc gaagcacaaa cattggccaa tgtttattta gcgttagaca atgatttgga
     5821 gatcctgcca gtcatcaata aaatcgacct acccgcagca gatcccgaac gtgtccgtca
     5881 agaaatcgaa gacgtaatcg gaatcgatgc tagtgaagct gtattagcca gtgccaaatc
     5941 agggattggg attgaagata ttctcgagca gatcgtggaa tatgttcctg caccaagtgg
     6001 agacttagat gcaccgctaa aagctttgat ctttgactct atttatgata gttaccgcgg
     6061 tgttgttcta aatgtccgga tcacggacgg tatggtcaaa cccggagaca aaatcaaact
     6121 gatgagtaat ggcaaaacat ttgatgttac agaggtcggg gtcttctcgc caaaagcagt
     6181 tgctagagac tttttgatgg tcggtgatgt cggttatatc acagcaagta tcaaaactgt
     6241 ccaagataca cgagtagggg atacagtaac gttagcagac aatcctgccg ctgaagcttt
     6301 accaggttac cgaaaaatga atccgatggt ttattgtggt ctttatccaa ttgatacttc
     6361 tcgttacaac gatttgcggg aagctttaga aaaactgcaa ttgaatgatg ctgctttaca
     6421 attcgaacca gaaacctctc aagcattagg ttttgggttc cgctgtggat tcctcggact
     6481 tcttcatatg gatgtcgtcc aagaacgctt ggaacgggaa ttcaatctag aattgatcac
     6541 gactgcacca tccgttattt accatgttaa taaaacggat ggtacgactg ctacagtaga
     6601 taacccggca gattttcctg aacctgtaac gattcaggat gtagaagaac cattcgtcaa
     6661 agcacagatc atggtcccaa atgattttgt cggtgcagta atggaacttt ctcaacgaaa
     6721 acggggagaa ttcattacga tggattattt agatgattac cgagtaaatg tcgtctataa
     6781 tattccgctt tctgaaattg tctttgactt tttcgacaaa ttgaaatcaa gcacgaaagg
     6841 ctatgcctca ttggattatg aaatgtctgg ttatcaaaaa agcaagttag tgaagatgga
     6901 catcttgctg aatggagaaa aagtcgatgc attaagcttt atcgttcacc gagactttgc
     6961 ctatgaacgt ggaaaagcaa tcgttgaaaa actgaaaaaa ctaatcccac gccaacaatt
     7021 tgaggtgcca atccaagcag ctattggaca aaaaatcgtt gcccgttcag acatcaaagc
     7081 cttgcgtaaa aacgtcttgg ctaaatgtta tggtggagat gtttctcgta aacgtaaact
     7141 cttagagaaa caaaaagaag ggaagaagcg gatgaaacaa atcggctccg tcgaagttcc
     7201 gcaagaagcc ttcatggccg ttctgaaaat ggacgaggac gaaccgaaga aatagcaagg
     7261 gtttgtttga aaacagtgta aaaaataaac catgtttaca tggatttgcc accggtttgc
     7321 caccggtggt ttttttcggt ggcaaaaatc aagaattctt tctaagattt tccatgatat
     7381 cgaccgtttc atttctcatc ttatctgtta catgcgagta agtatccatc gtaattgaaa
     7441 ttctgctgtg gcccaatcgt tcagagattt ctttcatttt tgcgccattt tcgagaagaa
     7501 gtgtagcatg agtatgtctg agagaatgga agttaaaaga gagggagagt gcattcgata
     7561 tcctcctagt attccatttc actacacttg gcgtaactag ctcaccgtct tccttcgtac
     7621 atactgcatt tgaatcaatg tagagctttc catacttcat tcgattttct aattgttgtt
     7681 tcttatgttt tttcagaatt gctagcaagg tttgtccaat aaaaatcgtt cgattggaac
     7741 tgcttgtctt tggcgtacca tatacccatg cgccgtcatt ctttaccatt tgtttctcta
     7801 cagtaattgt tccatttgaa aaatcgacat catcccacgt cagaccacaa acttcgccaa
     7861 cgcgcattcc cgtataaaat ccaatattca aaggaatata gaaaggatgt ccttcaggag
     7921 taatttctag catatgatca aagtcctcaa gagaaatgat ttttagatct tttttagtcg
     7981 ttggtcgtgc ttcatatttt ggtattttta catacagcat aggattttgc ttgattaatc
     8041 cccaaggata aaccgccata ttcagcgcat tcttaaggac agagtgagta atagtcattg
     8101 ttttcttcga gtaacccttt ttaaattcag cattgatgaa attttgtaaa agagcagggg
     8161 agagatccgt aagttttttc tttcctaaat aaccgtttat atgatttttg atggtaaatc
     8221 ggtagttttc ataggtattg tattttagat ttagtttaac gtattcctcc atccaaaaat
     8281 caaggtattg ttttactcga gtatccgtac ctaaaaagta ttgtcctgtt tcgtcaatat
     8341 ctgataaaac ttttcgtaaa gcagcttcgg cctctggtcg ggtgtctccg ccaactttct
     8401 ccactttttt tcttgagcca tcatcattga tatct
//
LOCUS       DACDAF010000106         8230 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.110, whole genome shotgun sequence.
ACCESSION   DACDAF010000106 DACDAF010000000
VERSION     DACDAF010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.110"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            329..1252
                     /gene="truB"
                     /locus_tag="IVZ69_002419"
     CDS             329..1252
                     /gene="truB"
                     /locus_tag="IVZ69_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HAP8184453.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1256..2197
                     /gene="ribF"
                     /locus_tag="IVZ69_002420"
     CDS             1256..2197
                     /gene="ribF"
                     /locus_tag="IVZ69_002420"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HAP8184454.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2592..3377
                     /locus_tag="IVZ69_002421"
     CDS             2592..3377
                     /locus_tag="IVZ69_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP8184455.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3390..4241
                     /locus_tag="IVZ69_002422"
     CDS             3390..4241
                     /locus_tag="IVZ69_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HAP8184456.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4365..4817)
                     /locus_tag="IVZ69_002423"
     CDS             complement(4365..4817)
                     /locus_tag="IVZ69_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8184457.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5282..5650)
                     /locus_tag="IVZ69_002424"
     CDS             complement(5282..5650)
                     /locus_tag="IVZ69_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chaperone"
                     /protein_id="HAP8184458.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5800..6282
                     /locus_tag="IVZ69_002425"
     CDS             5800..6282
                     /locus_tag="IVZ69_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HAP8184459.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6319..7329
                     /locus_tag="IVZ69_002426"
     CDS             6319..7329
                     /locus_tag="IVZ69_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HAP8184460.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7444..8157)
                     /locus_tag="IVZ69_002427"
     CDS             complement(7444..8157)
                     /locus_tag="IVZ69_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184461.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2785 a         1337 c         1667 g         2441 t
ORIGIN      
        1 attaagaaac tgaaaaaata aataaaaaaa aacggaaaaa agactggaag aatggacagt
       61 cttttttttc gtttttggga agtgaaaacc aaactattta cctgtaagcc acccataaat
      121 ccaatcaaat ggtgcaaaga aaaaatcttc cattctattc cctcctttaa aaaaaacata
      181 acatgatttc tatttacgtg agcatgaatt ttgttacgtt tttattgccg aaaaataaaa
      241 accgttcatt atgatgtcaa attcgtcagt aattgatgca atgtgttata ataattcagt
      301 taaatcaaaa atgaaatgga gaaaagacat ggacgggtta ttaactttat ggaaagaacg
      361 cggaatgaca agtcatgatt gcgtattcaa attaagaaaa atcttacata cgaaaaaaat
      421 cggacatggg ggtacgcttg acccagacgt agacggtgtg ttgcccattt gtattggaaa
      481 agccacaaaa gttatcgaat atttgacaga ttctgggaaa atctatgtag gcgagataac
      541 tctaggtttc agtacaacga cggaagatcg atccggagaa cgggtagaaa caaaaccagt
      601 agatatgtct ttatctgaag aaaaaataga tgaagtgatg gcttcattta ttggtgagat
      661 cacccagata ccaccaatgt actcagcggt aaaagtcaac ggtaagcggt tatatgaata
      721 tgcccgcaat aatgaaacag tggagcgtcc tgttagaaag gctcagattt accgttttat
      781 ccggacaagt gaattgacaa gagacgaagt gacaggaacc atttcttggc gcttcgaagt
      841 agaatgcggg aaaggaacct atgtccgcac attagctgta gatacaggca agaaacttgg
      901 ttaccctgcg cacatgtctg atctgacccg aacagcaagt gccggtatgt cccagaaaga
      961 tgctctgaca ttagaagaag tagctcaagc tgtgaaaaat gggacaatcg atgattgttt
     1021 gctgccaata gaaaaaggag tgaaacgatt caaacgagta gatattactg atgaagtatg
     1081 gcagaaagta aaaaacggta tgagacttaa ttatactgta tttgcgctcc cagaaatgcc
     1141 gtcagaagaa attgctttgt tttataaagg caaagttgtc agtatctatc agccaaaccc
     1201 gaaagaaaaa aacaaattaa aacctagtaa agtattgaga aatgaggaat aacgaatgaa
     1261 tatcatcaag atcagacatc cttaccaatc agaacaaatt ccagaagacg atgtcgtttt
     1321 agtactagga ttttttgacg gcgtgcatat tggacaccag aaagtcataa agacaggtat
     1381 ggaaattgca caaaaagaag gattgaaatt agcattgatg actttcaatc agcatccatc
     1441 gattgtcttt aaaaagatcg atcctagcag cgtgaaatat ttgactagcc ttaagcaaaa
     1501 agaagaaaaa atggccgctt tgggtataga ttatttatat gaagttgatt ttacttcttc
     1561 ttttgctcat ttagcaccgc aggaatttgt tgatcaatac atcgtagggt tacatgcaaa
     1621 atatgctgtt tccggttttg attatacgta tggaccaaaa gacattgcag atgtcgctca
     1681 ttttcctgaa tatgccaaag gaagattcaa aatcgtcaca gtttctaaag aagaagaaca
     1741 aggtgaaaaa atcagctcta cccgtattcg aggattacta gacagcggac aagtaaaaga
     1801 agcagcaaaa ctattaggtt gcacatatga ggtagaaggg gtagttgtcc atggcgatgc
     1861 acgaggcaga ctactaggat tccctacagc aaatgtcaaa gtaaagagca cagttcattt
     1921 gcctaaagaa ggtgtttatg tatcggaaat aaaaattggg gaaatttggt atccagccat
     1981 gggttcaatt ggacataatg atacattcgg tgaaggacgg gagctgactg tagaattgta
     2041 tattttggac tttaatcaag atatctatgg tgaacatgtc gcagtacgct ggaatcaatt
     2101 tttaagagat caagtgaaat tttctagtgt agaggaattg attgaacaac tcaaagagga
     2161 tgaacaagca acagctgaat atttttctca gcaataaaac attatgcata aaatctcttg
     2221 tttatgtata actagcaatt tcaataaaat gggtgataaa taagcccagg aaaggggctg
     2281 tgacaaaagt cttgtcacag cctttttttc caaataaatg gtttttcaga agtagcttct
     2341 tcggaaataa gccgaaattt cacaaaaatt tgagaagtaa tttttgtaaa ttacttctta
     2401 tttcttgaag ctggccactt ctgtcacaac ctctttcttt atagaaataa aaggacacta
     2461 gcaattcatg aaaacgattg ctaaagcgta tcatttgctt tagactatat atcttggtgt
     2521 acactcactt taagacggaa ataaaagtta tccgtaataa caggtttagg tatgaaaaag
     2581 gagtgggtac tatgtataag gaattagaaa acaaagtcgc agtagtaact ggtggctcaa
     2641 aggggattgg aacagcgatt gctcaacgat tcgggaaaga aaaaatgaat gtagttgtca
     2701 actataactc ggataaagaa ggagcagaaa aagcagtcaa agcaatcgaa gaggcaggcg
     2761 gaaaagcagt ctctgtacaa gcagatgtca gttctgaaga aggaatacag cgtttacttg
     2821 atacggcttt agaaaatttt gggacactgg acgtttggat taataatgct gggatggaaa
     2881 atcagcatcc aacccatgaa cttagccttg aagattggga aagagtatta aaagtcaatt
     2941 tgactggcgt ttttatcgga acgaaagcgg ctttaaatta ctttacagag aatgataaaa
     3001 aaggaaatat catcaatatg tcttctgttc atgaacaaat cccatggcca acgtttgctc
     3061 attacgctgc ttcaaaaggc ggagtaaaac tattcaccga aacggtagca atggagtacg
     3121 caccaaaggg aatcagaatc aatagtatag gacctggtgc tatccgtaca cctattaatg
     3181 cggcaaaatt tgatgatcct gaacaaaaag aactcttgga aagtatgatc ccactaggac
     3241 gcgtaggtga accaaaagaa atagcggcga cagctgcatg gttggcttca gacgaatcca
     3301 gttatgttac aggtattaca ctatttgcag atggtgggat gactttatat ccttctttcc
     3361 aaggtggaaa aggataaggg tgaataaaaa tgggtttatt gattgcattg atcccggcag
     3421 ttgggtgggg gatccagcca ctgattttga aaaagattgg tggcagacca acaaatgaga
     3481 tattaggaac tggtattgga gccgtgctcg ttggcttact tgttcaatta ttcgcttctc
     3541 cagctggtat ttcagtgact acatttttga ttagtttact ttctggtgca ttctgggtca
     3601 tcggacaaac aggacagtat acatctttca acttgattgg tgtttctaaa acgatgccaa
     3661 tttcgactgc attacagtta gtcggaacct cattgattgg tgtcttcgct tttggagaat
     3721 ggtctggaag tatgggaaaa atcattggtg cagcagcaat cattcttctt gtatttggtt
     3781 ctgctttaac ggcaatcagt gatgatcctg gaaaaaaagg cggtatcaca aaaggaatca
     3841 gtctattagc atcaacaagt attggttatt gggtttacag tgcattgccc aaactagttg
     3901 atgcaagcgg actttccatt ttctttccgc aaatgatcgg tgtcttttta ggggcagtga
     3961 tttatgtgat tttccgaaaa ccaaccgcat tttctgaaga caagagttgg aaagcaacaa
     4021 tagttggagc catcttcagt gtgtcagcat tggcttatat tttttcagca aatgaaaatg
     4081 gggttgctac tgcatatatc attacacagc taaacgtagt tatctctaca ttaggcggta
     4141 tgtacatcct gcatgaaaat aagacaccaa aagaaaaaaa attaacgatt atcggattat
     4201 tgctgatcgt agtaggaagc atggtcacgg tctttatttg aggataaaga tggtaaaatc
     4261 tcatttatta aaaaaatatt tgtttgaacc aaacagtaag tacttataaa aaaatagcgc
     4321 tagaatttcc aacatctctg gaatttctag cgctttttaa ttgtttaaga tacaagtgaa
     4381 atatctgtct gcatcaataa tttttcattg atccattgac taaaatttac gacatgattg
     4441 aagttaccac cgattagtat ctccgcatga ttgtctttat aaagatcgta ttgtaaaaga
     4501 cggtcttttt tatttgcgta aacatcgtta tggtactgga ctaattgttc tcggatttga
     4561 ttgattgctg taaaatcacg atactgaagg ttgaaacgca tcgtgattgg tgcatttagc
     4621 atgaatcgct gcatttcttt tgctgcttcc tctgcttgat ctccgtatag gaactcaaaa
     4681 agattacgtt cagaaaattt ccattgcccg ccaacctttg ttccttttag ttttccttca
     4741 tgaagataat ttctgataga acgtgtagta acacctaatt gttcggctaa ttcatttact
     4801 gagtaaaaat ctttcaatgt tcaccctcct atgtgaatgg ttctactgac ttagttgata
     4861 tttgcttaat cacgaaatgt agaaagaacg attttaatta aggtcattgt aaaaatcaag
     4921 tcagaaaatt ctaacttttc tttctctaaa gaaattcgtt ctctcctaaa gtgatattat
     4981 atttaaatat acctgaaaat aatgggcagt attatgaaag atcactgata ttttctcgta
     5041 ttttttcctt attcaaaagt tttgcaggaa aattgctgaa aaaataattt tactaagtgg
     5101 aaaattcaaa gccattcaat cagtgatttt tttcagcaca agaaagactc cttataaaaa
     5161 tagcagatac tttgtcaatt aagtgtttaa ccagggatga taaaaaggat aggattgaac
     5221 aaaacctgta taagctgatg aatagtttcc tcgccagtaa aaggtttatt cgtataaagc
     5281 tttatcgcca aaatttatca tgaccttttt tatcttcaat attaaatgaa atcaattgtt
     5341 caatcaattc ccagttgatt acacttttcc aaggaacttt gatgacgtta tccgtatata
     5401 cgtagcctgc ttcttggata tttttttcaa gggcacgaat cgctgctttt tccggtgcga
     5461 tagaaaaatg atttttagca aaactaaatg caataataaa ggtaccatgg tcagtaaaca
     5521 taggttggtt ccattttaca gttgtgtcta gctggggata cgtttctgtt atcttagcaa
     5581 aaaggtcttt gatcttttgt tgatgttctt tttctttgat ctgattgatg atcggctgaa
     5641 atttttccat tctaaaacgc ctccattaag tggtttgatt tattttacca gaaaaacaat
     5701 agttatgtat aaaaaacgaa caaaacacaa gtaatgttgt aaccgctata tttatatgat
     5761 aagatgtctc aaataataaa atagaaaaga gacataaaaa tgattgactt ggcaaagaaa
     5821 ttcttacacg aaaatatata ttttgagttg tatcatcatc gagccattta tacaaatgaa
     5881 gatgctttgg taataaagaa agaacaagga tttacaggta cagagaccaa aagcttattc
     5941 ttaaaagata aaaaagataa taactacgta tatctgactt ttactacgaa acaaacggat
     6001 ttcaaagcat tagggaagat cgtcggtaaa aggctttcta ttgtttcatc agaacgcatg
     6061 gaagaacaaa cgggacaaaa gcagggcgct gtttctccgt ttggttatga aaaacagatt
     6121 ccgattatta ttgatgaaga gctcttatca aatgaaaaac ttgtttttgc accaggtaga
     6181 ccagatcaaa cgatggtcat ccaaacggtt gacttaaaca aaatcatcca gctacttgag
     6241 atgccgatat ttttgatgcc ggcaaacgaa aaaaacaatt aaccaagtaa aatagtgcat
     6301 acttggaggt gaagcaacat gataagttat ccattattag aaagaaatgc aacgattggg
     6361 gttactgcac catcctcagg cgtatcagag gaacaccatt cgttactcga atcagcttta
     6421 aagagaatgg aagaaaaatc tttccaagta gttactggaa agacgctttg gacgcaagat
     6481 aaggaaaaat caggtccagc aagaaaacga gcagatgaat tcaatcaaat gatgcaagat
     6541 gaaaatatcc aaatgatctt tccgccttgg ggaggagaat tattgattga gattctcgat
     6601 tttgtcgatt ttgatgctct acaaccaaaa tggatagtag gttattcaga tattagtacg
     6661 ttgctacttg ctgtcacatt aaaaacaggg atagccactg cacatggaac caaccttatt
     6721 gatttaagag gagagtactt ggatgaaacg acagcaatgt gggaaagtgt actgaaaaca
     6781 agagaaggag aatcgattct acagcaacct tctgaaaagt atcaaaaaga gtggccccat
     6841 gagcattcat catcttctgt tttccatctc actgaaccaa caaattggca atcagtcagc
     6901 ggagatgcag taaggatgaa gggacgatta ttaggtggct gtattgatac gatcagtcat
     6961 ttaatcggta ccccttatgg agatgtccaa tcttttaaaa gaaagtataa tgatggaaag
     7021 ccgatcttgt ggtttctaga aaattgtgag ctatcgtcag ttgatttaag aagatcactt
     7081 gttcagatga aactggcagg atggtttgat ggcagctcgg ggatcatgtt cggtagaagt
     7141 gcagcagagg atttgttaga ttataaaatg aaggatgtat atgaagatct gtcaaaggaa
     7201 ttaaaactac cgatcttgta tgatattgat tgtggtcatg taccgccaca actgacattg
     7261 atcaatggtg cctatgcaga agtagcggta gaagatagaa aagcgactgt tttgcaaacg
     7321 tttatttaaa aaattttttc ctgccttgga gtttatcaaa gaccaacaaa tctaaataga
     7381 aaagaaaatg aaagaagctg acagtatttt gccagcttct ttttgtatga tctattagaa
     7441 attttaatta tccataacta tcacattgat cagctgtttc acatcatttg gattacctgt
     7501 aggaatagct actacagatg cattatcaat aatttcttga gttgtttctc taatgaacgc
     7561 tggataagat gtttgatctg caggcatttg ccaatgtgaa ggaactggat aactagtgat
     7621 tgtcccgtca tggttacttg aatacactaa aactccctgg taactgtatt tcccagtgag
     7681 cataaccaca tctttcggat agactgcact ccctgcatca taaggggcga taggtgttcc
     7741 tgcaggataa tgaataacat gtagttcgaa atcacccgat gtatctctaa aagtattacc
     7801 tctaattgct agccaaacac gtgcgtactc aatttgtaga tcagaatatc ctgctaacgg
     7861 atctattgac tgagaagact gtgaggaagt tgtgtctatt gttgaagaag aaatatttgt
     7921 ctcaactgta ctactagatg tagaagaagt attgggctct gagactttac tgcttgttga
     7981 agatgtattc gtttcagtag aagctgattt ctgagtactt gatttttcag ctgaactggt
     8041 ttgtttgatt gaacttttgt ctgtggtcgc agatggatca ctattttctt tactaggaga
     8101 cgtacatcct acaaggaata aagagaccaa caataaaata aaacctaact ttttcatata
     8161 aaatacctca ttattttttt aataccagta tagcataatc ctgaattttt gaatccgtaa
     8221 aaccttgtct
//
LOCUS       DACDAF010000107         8135 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.111, whole genome shotgun sequence.
ACCESSION   DACDAF010000107 DACDAF010000000
VERSION     DACDAF010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.111"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(342..1241)
                     /locus_tag="IVZ69_002428"
     CDS             complement(342..1241)
                     /locus_tag="IVZ69_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HAP8184462.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDEDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSSLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
     gene            complement(1262..1535)
                     /locus_tag="IVZ69_002429"
                     /pseudo
     CDS             complement(1262..1535)
                     /locus_tag="IVZ69_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
     gene            complement(1558..2964)
                     /gene="lacG"
                     /locus_tag="IVZ69_002430"
     CDS             complement(1558..2964)
                     /gene="lacG"
                     /locus_tag="IVZ69_002430"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HAP8184463.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRLKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            complement(3106..4812)
                     /locus_tag="IVZ69_002431"
     CDS             complement(3106..4812)
                     /locus_tag="IVZ69_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8184464.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            complement(4812..5129)
                     /locus_tag="IVZ69_002432"
     CDS             complement(4812..5129)
                     /locus_tag="IVZ69_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HAP8184465.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            complement(5157..6137)
                     /gene="lacD"
                     /locus_tag="IVZ69_002433"
     CDS             complement(5157..6137)
                     /gene="lacD"
                     /locus_tag="IVZ69_002433"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HAP8184466.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            complement(6140..7072)
                     /gene="lacC"
                     /locus_tag="IVZ69_002434"
     CDS             complement(6140..7072)
                     /gene="lacC"
                     /locus_tag="IVZ69_002434"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HAP8184467.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            complement(7083..7598)
                     /gene="lacB"
                     /locus_tag="IVZ69_002435"
     CDS             complement(7083..7598)
                     /gene="lacB"
                     /locus_tag="IVZ69_002435"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HAP8184468.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            complement(7615..8040)
                     /gene="lacA"
                     /locus_tag="IVZ69_002436"
     CDS             complement(7615..8040)
                     /gene="lacA"
                     /locus_tag="IVZ69_002436"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HAP8184469.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
BASE COUNT         2496 a         1691 c         1398 g         2550 t
ORIGIN      
        1 acgctatatt taagatttca aacaactata ttaataggaa gaaaatttca tttttcctct
       61 tagttctata aaaagtgtgg ctaatttgag gcaaaatatt aaattaaatt tgccacaaat
      121 taatggctcc actattattt taaatcaaga agtagtaaat aatcttattt tttactacca
      181 gactgtcttt agatattagc ttttcgtcac ccactacagt tgacatagac ccacaaaaaa
      241 cttaaaaacc ttgcgatgta agactggcac ggagaagacc aatctatcat cacaaggtaa
      301 gagtattcaa atcttattga agactcaaat aataacaaat tttaattaag gatagtaata
      361 tcatagattt ttctagaagt ttcttgaggt gaaattttcg ttacctgtct tttatcttct
      421 aagaaattac cttcttcaag tgaagtggag agaccactcc aaggttccaa agcaatgaat
      481 ggacttttat tagttgtaga ccacagaatc aagttcggaa aatcatcaaa atctactcga
      541 agacctttac cagacttcct tgaccgaagc gttacgctac gagacttgag ctggtcaagt
      601 gtaatggcat catgggaaaa aagtgagtag tccaaatcga gaattttttg attttccaaa
      661 aaaggtgtcc gatcttgcaa atctaataat cctgtctcag gaaaactctt tggtatcgag
      721 caagactcaa cctcactaaa ttcaatataa taatcctcat agttttcacc ttctactaaa
      781 gaactattga atgctggatg ggctccaata aagtaaggca ttgttttttc catttccaag
      841 ttcgttacct gaaattcggt tctaattgat ttaccattca aggtataaac aactctcagt
      901 tcaaactgat ataggtaatt atcaagcatc tcagcatttg gtttaatact aaaggtcacg
      961 ctattatcat tgacttcttc cagaataaat tcttcttttc gaacaaaacc atgtctacga
     1021 ataagacctg taaaaaaagg tctttcttga ggtctataaa tagcccaatc atttcgtaaa
     1081 ctaccacaga taggaaatag aataggcgcc tgtccattcc aataatttgg atcagcttgc
     1141 cagagatact ctatcccatc ctcgtcttta atcgaagtca gttgaccacc aagtgtttta
     1201 aactgaacag taagatactc gttttttaat tcgatagtca caactaattc ctttcttttt
     1261 attattggaa aggcaaataa tttacctcga agtgaatagt ctcacgtatt tctacatcga
     1321 gtgattgtaa aaattcccat tcaaatgctg ataactctaa atcagaatgg caaatccact
     1381 cttttccagt taaaacatac catttaccac attttagcaa cgagggtagc ttcaagctca
     1441 ggaatcatag gacaatcttc gaaactaaca atatatacct tttcaaagcc tggtctaaat
     1501 aagtgttgta ctttttctaa agtatcggat aacaattttt tacattttca agtaatatta
     1561 ctctatcact tgagtttctg ctactttctt ataccaatga gctgatttct taggatagcg
     1621 ttcttgcgtg tcaaagtcta catagaatag tccataacgt ttttcgtatc cgtttgacca
     1681 tgagaagaca tccataagtg accagatgaa gtaaccttta acatttgcac catccgcaat
     1741 tgcgtctgat aaaacttcca agtgtttctt cacgtaatca atacgaccat catcataaac
     1801 ggtattatct acaaactcat ctttgtatcc aagaccgttt tcagtgatgt aaatcttctt
     1861 gtagtttgga taatcatttt tcaatcgcat gatttggtca tacaagcctt caggataaat
     1921 aatccagtcc caatccgttc taggcacata atctggtgcg attcggcgac caacaccttt
     1981 aatctggtac ttagaacttc ctttttcacc cttaccattg tgaatgattt cagtctcacc
     2041 atcaaaggct tgcatccaat cactcatgta gtagttgata ccaaggaaat cgttcaaatc
     2101 tttagctgct tcaagtgctt ggaagtcttc atcacgaaga tcaagttctc caccattttc
     2161 agctaggatg tggttgaccc cttccatcgt tttatctgaa tagtgtccaa ggtaggttgc
     2221 atccaagata aatttgttat ggatgatatc ttctaactca gcggcacgaa catctgctgg
     2281 attttctgga tcataagggt atttggttgg caacgcatgt actacaccaa tttcgccttt
     2341 ataaccttta tctttataca atttcacagc acgtgcatga gaaaccatca tattgtggtg
     2401 tgattggaag actttggcaa gatcatattg aatgcctgga gggaatttac caaccaagta
     2461 ttgaccatct ccaattgggc caatttcatt gaaagttgtc cagtagttta cttctgggaa
     2521 ctcttcaaaa cagaaagcgg cataatctac aaagtgttct atattttcgc ggtttaagaa
     2581 atctccatct gagtgaagaa cttctggtgt gtcaaagtgg tgcaaagtca cgaatggctc
     2641 aacatgacgt ttgtggcact cggcaaaaag attatggtag aattcaacac ctttttcatt
     2701 tacttcgcca tagccagttg ggaaaatacg agaccaggca attgaaatac gaataccatt
     2761 aacgccatat ttttcagcta attctaaatc aacaggatat ttatggtaaa aatcacttgc
     2821 aggctctgct gtgtaccaat aattgtcttc aagatactta tcccatgcaa ctgggccttt
     2881 accatccgtg tgagtcgcac cttctgcttg ataagcagct gtagcaccac caaaaataaa
     2941 atctttagga agtgttttag tcataactat aaatcctttc aaaaaaagca tttgagacga
     3001 tattctgagt tccggaaacc aaggaaatga aatgcaatga tatggttaac aatattataa
     3061 ggaactgaaa gaataatctc gtctcaaata acttttacaa atttattaat caaactgttg
     3121 ttgaacaaat gcaagagcac cttgtccatc acgtgtcaat ttgatatatt gagctccttc
     3181 agtttttgca agtttaatgc ccaatttatc cgtttcagcc ttcatatcat cgaagtttga
     3241 agcgacctgc ggagccaaga taaccaagtc aaactctggc aacatttcac ggtgagcacc
     3301 gtaactaccc gctgccgctt tgactggaac attgtattct gctgctgctt tgttcaaggc
     3361 attggcaagc aagccacttg tacctccacc tgcacaaaga acaaggacat tagtttcttt
     3421 tgtgatatta ttgtttgctg ctacatcttc tttagcaacg cctgcttttc caagaacggc
     3481 atctgcttta gcagtattga agtttgcagc tactttttct ttaagagcat cgtttgtttt
     3541 accagaacgt tcttcttcaa gaatttgttc atcgtatacc ttaacaaatg ggtaataaat
     3601 gatagtatca acaactacca agagtccggc taagataaat gatagaactt ggaagttagt
     3661 accgagtaca attcccaacg gaccaggagt aacccatgga aggttggcag agaatgagtt
     3721 catgttcaat gtgtcaacaa agaatttaaa gatccaaacg ttgacaatcg gagcgaaaat
     3781 gaacggtaca aagaaaatcg gattcaatac gattggtgca ccaaataaga ttggctcatt
     3841 aaccccaaag aatgttggaa caactgaggc acgtccgatg gcacggttac gttctgattt
     3901 acaaatccac atgaacaaga atggaacaat caatgtagct cctgttccac ccatggtaac
     3961 aataaacatt tgagtaccag aagtgataac tttatctgca tgttgtccag cttggataag
     4021 atgcaagttg gcatcgatat tggcataagt gatagcagcg attgctggtt cgacaattga
     4081 aggaccgtgg ataccaacaa accagaagaa ggcataagca ccaaagataa gtgtaattcc
     4141 aaggtaacca tctgcagctg agaagagagg agcaagaagg gtaccgattg attctgcaac
     4201 ggttacacca agagttccct taacaatgag ttcaaatcca taaaggagaa caaccgctac
     4261 agtgaatgga atcaagtctt taaatacttg agagatattt ggtggaacct cttcaggcat
     4321 acgaatagta acattatttt tcacacagac cttgtaaaca ttaactgtca caaaggctgc
     4381 aataaatgct gtcaaaagac cttttgttcc cgtgaaggct gtcaagaagc ctccttcttt
     4441 tgcaggctca gctgccatca aaaggaaccc taccatagac gctagcatcg tagataagaa
     4501 gttaatctga ttggtcgcag gtaggtcacg gttcattgag tccgtcaaag ctttagcggt
     4561 agtaccacca acaaagaatg ctaggatacc catcgaatag ctataaggag tcatcaagaa
     4621 ggtctcaatg tcttttgacc agtggaatcc ccaagcattt gggacatagg caataaggat
     4681 aaagatagat gagaaaagga tgactggcat accagcgata aatccatcac gaatagcacg
     4741 aagatagatg tttcgagaga ttttctcaaa gaacggtttc cctttctcaa taagttcaat
     4801 gagtttatgc attattttgc tcctctttta taaagttcga tgaggtgatg aatcacatct
     4861 tttaataaga cagtagtcat taagtggtcc tgaccatgca tcatggtaac gctgtatgga
     4921 agttcctccc cagaagcttc tcgagccaac atagctgtct gagaattgtg agcctctgca
     4981 atacagcttc ctgcttctac tacaagacta tctgccttag cgaaatcacc attttcagcc
     5041 gctttaagcg cttctaaaag tttagagcga gcatctccag cataagcaac aatttcaaac
     5101 cctaagagag tcatctcttc tctgttcata acaatatcct ccgttttatg tttttactat
     5161 actttatcag tccatggact agctgtttta acaagaactt tgttaagttc atcaatattt
     5221 tcgaatccag tagtacgcaa ccattcacgt gctgcttttt caccttcttt gatgtaaggt
     5281 tctacagatc ctgcccaagt agcacgtcca caaagcacac cattaaactt ggcacctgag
     5341 tcgtgagcaa attgcaatgt ttcttggaac aatttagcag atacacctgc acttaggtag
     5401 atgtatggaa ggttagtcgc ttcttcttgt gctttaaaga agtcagcagc ttcagcttta
     5461 ctgtaaacca cttcaccatc agcaaaacct tcgacatatt taacgttaac tggtacttct
     5521 actttaagaa catcaatgtt aaagcgtgga tcagagaaaa ctttcatcgc ttcaatgact
     5581 ttgcgaggtt tcacttttgc atattcaaca gaacctgcat ctgagatttc ttcatcataa
     5641 gcaaggattt ccaagaagaa aggaatatct tcagcgacac attcagaacc aacacgttca
     5701 atataagctt gtttttgttg gttaagttca tctgagctgt ctacatcata gtaaagcaag
     5761 aacttaacgg catcagcgcc ttgctctttg atacgttttg cagaccaaac atccaagcag
     5821 tcaggcaaac gttttgtact tgatgtatca taacctgttt tttcataggc aagaagaaga
     5881 cctgcttctt tatccaatgc ttttgttgct ggaagtccat attcagggtc aagcaacatt
     5941 gaagaagcgt attttgtaag ttcatcagca accaaaacct ttagttcttc catttgagct
     6001 acagttggtt ctgtatcttg atactgtgcc atcaaacgtt tcaaagcacc acgttggtca
     6061 aatgccaaag ctgagataac accgttttta tctgaaattt tttccaaaga tttgcgtttc
     6121 tgttctgtaa gtaccatttt tatacctctt ttactccaat ttgtgagttt agtgtttcgt
     6181 aattagtcat attcacatgc cctgtcattg tttcttgagc atttaacata cccaatgtca
     6241 tcgcatgttt taataagtca gcgtcacttt ttttactatt taaagctgat gcaataccag
     6301 ctaccgttga gtcccctgat ccgactggat taacaactgg gatatcagga atatctacct
     6361 tatagaaaac atcaccatgt tttgcaaagg caccgtttcg acctaatgag accactatcc
     6421 attcgatacc actaaaaagt gactctttaa gaacgtcttt gagttcttca atatcttttg
     6481 ttacttcttt tccaagcaac tgtgaaagtt cctcattatt aggtttgatg gcagtaggtt
     6541 tagccgacga ttttagaact gtttcaagag gtgcacctga acaatccaaa acgactgcta
     6601 ctccttcatc cgaagcaagt tggataagtt tttcataata atcgttggga agtcctgaag
     6661 gtaaacttcc tgaaattgtc acaacttctg attgtttaat aagattgcta tagtggtcaa
     6721 gaaagccttc tgcttcttca tgagaaattg ttggtccttg ttccaaaatt tctgtttggt
     6781 taccctcgtg taagatagca atacagtttc tagtgtttcc tgagatttta taaaaagctg
     6841 gactaacagg agattgttct aattcgcttt caataaattc accaatttta ccacctaaga
     6901 aacctgtagc agtaacttta tcaccagatt catacaagac tctagtaaca tttaagcctt
     6961 ttccaccagc tgtcttacta acatctttca ccctattcac tgtatcaatt ttcaatgttt
     7021 ctagaggata agagatgtct actgaaggat ttagtgtgac tgtcagaatc atttgttata
     7081 ccttaatcgt ggtagtcacc acggtcccat ctttcaagga attctgtaaa gaaatcttca
     7141 tctgcttgat gtgcattatg tgtttcaacg tgttcgattt ttgcaatcaa ttttttattt
     7201 tcttctgttg gtttgtactc agcttcaatg aaagcttcaa tgatgtcatt cataagaaga
     7261 ccaccagtaa tctttccacc gaaaccgata acattcgcat ttaactcttc ttttgcatat
     7321 atagctgatg tcatatcacg aaccaacgct gagcgaacac ctggaacttt attgactgca
     7381 ttgttaatgc cgacacctgt accacagata catactccca agtctgcttg accacttact
     7441 actgcttcac cgactttttt accatagata gggtagtgag tacgtgcgtg gtcatatgtc
     7501 ccgaaatcaa ggacctcatg tccttttgat ttcaagaatt ctgatactgc cattttttca
     7561 tctgtgacaa tgtggtcaca tccaattgcg attctcattc cttaactcct tttcttaaca
     7621 cattttgtta agcatatcta ctcggatttg atgacgtccg ccatcatatt taccattgac
     7681 gaaaccttta gcgatgtttt tagcaagctc atcaccgacg atttcagcgc caaccgtaat
     7741 cattcgtgaa ttgttatgtc cacgtgtcat ataagctgag cgttcatctg aaacttctgc
     7801 tgcaaccata cctttaattt tagttgctac catgaatgga ccagctccat aagcatcaat
     7861 tacaatacct aagttttgct catctttatt tacttcagag gcaactgcca aggtaacatc
     7921 aacaaaatct tgtccgtcct tagtcacatc aattacctca aaaccttctt ctacaagaaa
     7981 atttttcaca acatctttta atctcgtacc tttgagatct gcaccaacaa caatagccat
     8041 tttgaccacc tcctaaattt tagaaagaaa tgctacgtag aagtagaaaa cattttgcaa
     8101 aatgttcgaa aaaacgtttt catcatttct ttgtt
//
LOCUS       DACDAF010000108         8067 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.112, whole genome shotgun sequence.
ACCESSION   DACDAF010000108 DACDAF010000000
VERSION     DACDAF010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.112"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..884
                     /locus_tag="IVZ69_002437"
     CDS             <1..884
                     /locus_tag="IVZ69_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HAP8184470.1"
                     /translation="ISVPVALFSFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTY
                     NDYFQIGMIGMIVSLVVVLTVANISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVL
                     GVVLLDLQIILGFILAGIWALLFTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMT
                     LAMFNNSAAYASPYFSAIFGDWIPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILA
                     VVLAVNPTMSPAFLFPLFAITTIAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGW
                     IIGAILCLITFLLYGNA"
     gene            932..3061
                     /locus_tag="IVZ69_002438"
     CDS             932..3061
                     /locus_tag="IVZ69_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HAP8184471.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKNLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKAIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPHTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            3036..3725
                     /locus_tag="IVZ69_002439"
     CDS             3036..3725
                     /locus_tag="IVZ69_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184472.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKEIE
                     KRCTEYDLDYK"
     gene            complement(4133..4818)
                     /locus_tag="IVZ69_002440"
                     /pseudo
     CDS             complement(4133..4818)
                     /locus_tag="IVZ69_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(4954..5148)
                     /locus_tag="IVZ69_002441"
     CDS             complement(4954..5148)
                     /locus_tag="IVZ69_002441"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184473.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(5198..5638)
                     /locus_tag="IVZ69_002442"
     CDS             complement(5198..5638)
                     /locus_tag="IVZ69_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HAP8184474.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELEQLFQAYASLDDVNS"
     gene            complement(5642..6487)
                     /locus_tag="IVZ69_002443"
     CDS             complement(5642..6487)
                     /locus_tag="IVZ69_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HAP8184475.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVDWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLVANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAVYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            6636..8054
                     /gene="pepV"
                     /locus_tag="IVZ69_002444"
     CDS             6636..8054
                     /gene="pepV"
                     /locus_tag="IVZ69_002444"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HAP8184476.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
BASE COUNT         2480 a         1515 c         1714 g         2358 t
ORIGIN      
        1 gtatttcagt accggttgca ctgttctcat ttatgggctc gattatggct ggaatctttg
       61 ctaatatcgt caatttcaaa caatatcaaa cgatttatgc tggtttcaat ccagcggctg
      121 aaagctatac ttataatgac tatttccaaa ttggtatgat tgggatgatt gtaagcttag
      181 ttgtggtact aacggtcgct aatatatcaa tgaacaaaaa gaaacgctat gcaatggcag
      241 caaacgtacc agctgaaggt ggcgacgcac caatgatctc atggttagcc gtattattac
      301 cagttttagg ggtcgttctt ttagatcttc aaatcatctt aggttttatt ctagcaggta
      361 tctgggcatt gctgtttact ggaaaattgc gcggaggtta taaagaaatc tgtcgtcagt
      421 ttgcgaaatt atttacagat ggcgcagtcg atgttgcacc aatggttggt ttcttgatga
      481 ccttagcgat gttcaataat tcagctgcgt atgcttctcc ttatttttca gctatttttg
      541 gagattggat accgcaatca ccattagtct tggcaatcgt atttgctata ttgacaccac
      601 taggattttt ccgcggtcca atgaatctag tcggttcagg ctcagctatt ttagctgtcg
      661 tgttagctgt taatccaacg atgtcgccag cctttttgtt cccgttattt gcaattacaa
      721 cgattgctcc tcagcattta gatattacac aatcttgggt tgcttgggga ttaggttata
      781 caaaagtaac ttctcgagaa tatatgaaga aatccatccc aactggttgg atcatcggtg
      841 cgatcttatg cctgatcacg ttcttattgt acgggaacgc ctagtaaaca aaacgtcgat
      901 aaaaacgatt agataaatgg aggaaaagaa aatgaaacgt tttgtgcgaa tgggaattga
      961 tgttggcggt acacatacga aagcagtcgc aatcgataat gcgacgcacg aaatcatcgg
     1021 aaaatcttca gtgaaaacaa cccacgatga tgtccgtgga gtagctgcag gtgtcgttca
     1081 gtcttttcaa aattgtttgc gggaaaataa tatcagtcca gaagatgttg tgtttgttgc
     1141 acattctacc acacaagcga ctaatgcact gattgaagga gacgtagcaa aagtcggcgt
     1201 aatcgggatg gcaaaaggtg gattagaagg ttttttagca aaacgacaaa ctagattgaa
     1261 cgatatcgat ttagggaata agaaaaaaat agagattgtc aatgcattct tacctgtcaa
     1321 aaacttaaat gtagaccgtg tttcagaaac gatttcttct ttagaaagag aaagagcgga
     1381 ggtcttggtt tcttctatgg catttggagt agataatggg gaaccagaac gagttgttta
     1441 tgaagcagca tctgtgaaag cgatccctac aacgatggct tctgacatca caaaattata
     1501 tggattgaca agaagaactc ggacagcagc aatcaacgca tctattttac caaaaatgct
     1561 agatacggca acctcgacag aagactccgt acgagaagca ggggtcaatg tttctttgat
     1621 gattatgcgc ggagacggcg gagtaatgga aatcaatgaa atgaaaaaac gacctgtttt
     1681 aaccatgctt tccggtcctg ctgcatcagt catgggctct ttgatgtact tgagagcgtc
     1741 taatggtgtt tattttgaag taggcggaac aacaaccaat atcggggtca ttaaaaatgg
     1801 acgtccagca atcgattatt caattgtagg tggccaccca acatatatct cttcattaga
     1861 tgttcgggtt ctaggtgtgg caggcggttc gatggtacgg gctaatcagt caggaatcat
     1921 cgatgtcggt ccacgttctg cacatattgc cggtctagat tatgcagtat ttacggagac
     1981 agaaaaaatc aaaggtccta aggttgaatt tttctctcct aaagaaggag accctgctga
     2041 ttacgtcaag gtagtgatgg aagacggaga agaagtgact attacaaata catgtgcagc
     2101 caatgttctt ggattagtgc aagaagaaca tttttcttat ggaaatgtcc catctgcacg
     2161 aaaagccata caggcattag cagactattg tcatacgacg gttgaagaca tcgcagagca
     2221 gatcatggaa aaatcctatg ctaagattga accggtgatt ttagaattgg cagacaagta
     2281 tcacttggag aaagatcaga tttctcttgt aggtgtaggg ggcggcgctg cctcattgat
     2341 tacttacttt agtaataaaa tgggtgtgaa atattcgatt cctgaaaacg ccgaagtgat
     2401 ttcttctatt ggtgtagcac ttgcaatggt ccgagatgtt gtagaacgta tcatcccttc
     2461 gccaagtaaa gaagatatac gatcgttgaa aaatgaagcg atgaataaag cgattgaatc
     2521 aggcgctaca ccagaatcga tcgaagtcca cgtagaaatc gatccacata cttcaaaagt
     2581 aacggctatc gctactggtt ctacggaagt gaaagcaacc gatctaacca aggagatcac
     2641 aacagaagaa gcactagagc ttgctgcaga ggatatgcga ttaaataaaa atgaagtttg
     2701 cttattggaa aatacacctt tcttttatgt atgcggcgaa cagaatcgtt caaaaaatgc
     2761 tggaagtctt cggatcatcg atcaaaaagg atttatcaag gtccaacgtg gacatgcttc
     2821 atgtatgaaa acaactgcag ccaattatat gacagctgtc gaacaacttt gggaagatat
     2881 ggcagtttat caaactgaat tgattgcccg accagaattt tatctctgct taggagcaag
     2941 agtctctgat tttacagcga cggatctgga acaactacag cttttgatgg atctggaagt
     3001 atctactatg gaaccggagg aagaagtgat cgtcgttgcc ggaaatatca aacaaacata
     3061 agttagaaga gttactaaac gaattacaac agatccccga agaaatttgg ggattctacc
     3121 agtttcggcg agatttattt tggaaaaaga ttcctttgtc caagcagaaa attcttatac
     3181 aacaatcaat cgattgtggt atcgaaacgg catgtagcat caaaaaaaag tacccttttg
     3241 ccgatgtagg agaaatctgt gaacaaatgg ctgttccaat cgtttcctgt gaatcagagc
     3301 aaataaacga acgaatcact tttgcaactt atgcagaaga tgaagggatc cgattgatga
     3361 cggagccgtt agaaaaatta aaatgttcag gactagcttc gatctctaaa gaaacagcgc
     3421 aagctttgat tattggacat gaactatttc accacatcga agcttctgtt aagggaattt
     3481 atacgcaaag cgaaaaaatt gtgctgtggc ggttgccttt ttatacacat caatcaaaca
     3541 ttcgtgcatt gagcgagata gcagcgatga gtttttcaaa agagatgaat caaagcgatt
     3601 tttcgcctta tgtattagag gcagtcttac tttggccata taatgaaatt cgtagccaag
     3661 ggatcttaga agaaataaaa gaaatagaaa aaagatgtac ggagtatgat ttagattaca
     3721 aataaagaga ctgtgacaaa agtcgtgtca cagtcctttt tttccgaata aacggtgttc
     3781 tcctgtcaac tcctcggtca caagtcaaaa tattcaacaa acatgagaag ctgttttttg
     3841 aaattgttcc ttgtgactcg gagatgaacg gcaggctcac gacctcttgg aaaaaggtgt
     3901 tcaaaagctt gcatctgcgg taataagaac agccaagtta aaaacataag aagctatttt
     3961 tacttggctg ttcttattac ttgatgcagg gcagcttttt cacaacctct caataaacgg
     4021 tgtgcaatca gctgaccctc ggtattagct caaaaaaaac ggcaaaatat gaggaactat
     4081 tttgccgttt atttctctaa tactcaggtc aaaacgctga ttccaaaacc tcttatttga
     4141 tgggtctgtc ctgaatatct tcaaaataat cggggtaatt atgaatcacg tattcttgct
     4201 cctcgataat catatgtaaa tgcatcgtgc aaagaaatcc gacttcatca aagttatgat
     4261 caatcattga ttgaagcatt gtctgatgtt catctaatac tcgaccccag tctaattctg
     4321 aaatcgtcaa acgtaaccat ctgaaacggt tcaagtgcgt actataactt tctagccaat
     4381 cccaaatttc tcgttttcca gcaatttcat aacaagttcg gtgaaaatca gtatccaaat
     4441 caaaaaagct tttttatttt gagcgatcac tgcctgatcg gtttgttcta gtattttttc
     4501 tagtttagct tgatcttgct tggtcatttt cgcactgcat tcttgcagga tcggtttttc
     4561 caacttttcc cgcgtataac gggctaatga agcagatcgg atatcgattt ttgaaacata
     4621 agtgccggac tgtggaatgg tttttacaag ctcttgattg cgcagttgga tcagtgcttc
     4681 tcgaatcggt gtacgcccga tagctagttg ttcttctaac actttatcgg agattttact
     4741 tccgggtgct aactcggaat aaatgatttg tttacgtata gattcataag cttgctgttg
     4801 caaattattg ataaccattt aaccttcctt tctatgcaga tataatctat tataacataa
     4861 atcgcttaca aatcgtgtgg gcataaaaac acagtctgca aaaaaagccc tgataggcat
     4921 gcctattaga gcctcgaaaa gaaaaatatt gaatcaatct ggtcgtacct cttggatcgg
     4981 tttgacacga ccgccgattc ttttagcaaa agcttcggat tcttttttgt ctttgaaaat
     5041 gagcagattg tctaagtttt tttcccgagt gcgacagcca gttttatcga tgtaaccgtg
     5101 cattacttta acgacataca tggggatcac ctgctttttt cttttcatta tacgaactac
     5161 tcgacacaat acaagaaaaa tgcttagacg gtctttatta agaatttaca tcatccaaag
     5221 aagcgtacgc ttggaataac tgttctaact ccggattgac tttgctcagc ttcactaatc
     5281 gttgcgaatc agaaagtaaa aaacagtgtt tactactgcc agtagttttt aattttttgt
     5341 cttcagttcc cacaatttcg tagctaaaat ccaaccgtgt tcccgtatac ttttggatag
     5401 ttgggtggat gctcactttt tctccgtaat ggatcatttc tttatagctg caatttactt
     5461 ccagaacggg gatgatgatc ccagattctt cgattttttt atagggaaac cctagatgta
     5521 ccaataaggc tacccgagcc tcttcaaacc agcggatata attgctgtga tgaataatcc
     5581 ccatttgatc tgtttcataa taaaaaggtt ctcgcacata acctgtaaat ttctccatga
     5641 ctcatgcctc gttttccatt gattttttac aaaaataatt catccacttc ggaagtgctt
     5701 cgctgatttg tgtcggcaaa acaatatatt gttcttttgc cagctggtct ccaatgaaac
     5761 tatgaagata aacagctgct gcaatcgttt ggtcattttg aggaaactgg gctaaaaatc
     5821 ctgtgatcat cccagctaaa gtgtcaccca tgccgcctgt tgccatagca gcagaaccta
     5881 aaggattggt gtagaagtgc tggtgaccat aaatttttgt ctcatgactt ttcaaaacga
     5941 gcacagcacc gatttcctgt tgcttctttt tgttttcttt atcccgttgt tcttgtatcg
     6001 gtagagaact caaccgttgc cactccattt gatgaggtgt aagtacagtt tgttcgggat
     6061 agggtagcaa aagatgatta gcaacaagta aacttaaagc agagccatca atcaccagcc
     6121 attgttcttt tgattggttt tctagtactt gtttgaaacg ttccaaactc ttagaagaag
     6181 tacccaatcc gggaccaatc aagagtacat ctgcttgctt tattacggaa agaaactggt
     6241 cagtatccgt ccaatctaca atcattgctt ctggcagatg actgtgaaga gcactccgat
     6301 ttttttcatc agttactaca gtcgtgagac ccgctccact gtgtacggca gctaaagcac
     6361 tcataatgat tgctccgcca tattgttcat tgccgccaat caaaacgata cgtccaaatg
     6421 ttcctttatg tgaaatcttt ggacgaggtg tgatgactct tttcactagt tgttcgttta
     6481 tcagcatcga aaaacctcct tttactcatt atagcgtata ttttttttag agaaaaacag
     6541 ataagaaaag gaattgtcag attttttgaa ctattttttt ctgtaatttg tggtatcatg
     6601 aacacgaaga cttaaataag tggaggatta actttatgac aattgattgg caaaaagaag
     6661 tagaagcacg taaagaagac ttgcttgaag acttgaaaaa tcttttacgt gtcaacagcg
     6721 agcgcgatga ttcaaaagta acaccagatg caccatttgg acctggacct cgcgacgcat
     6781 tgaaacatat gttagcttat ggcgaacgtg atggatttaa agtaaaaaat gtcgataact
     6841 atgcagggca tattgatctt ggcgaaggag acgaaacgct agggatattt ggacacatgg
     6901 atgtcgttcc tgcaggagat ggctgggaca cagatcctta tgaaccagta atcaaggatg
     6961 gaaagatctt tgcacgcgga tcaagcgatg acaaaggtcc aagtatggca gcttactatg
     7021 cgatgaagat cattaaagaa cttgacttga aactatcaaa aaaagttcgc ttcgtagtcg
     7081 gcagcgatga agaaagcggc tggggcgata tggcttatta tttcgaacat gaagaagaac
     7141 cagattttgg tttctcacca gatgctgaat tcccaatcat caatggtgaa aaaggaaatg
     7201 tttctttagc tttacgcttc aaaggcgaca atgcaggaga ttatgtcttg aaatcttttg
     7261 tttccggact tcgcgaaaat atggtgccag gaacagcaac tgcagcactt caagtaccaa
     7321 gtgcagatgc agctatcgcg atggaagaag cattttacca attcatcgaa gcaaatccag
     7381 taagcggaac gattgaagcg gacaatacgt atgtaaaaat cgaattagtt ggtaaaggcg
     7441 cacatggtgc aagcccacaa tctggtatca atgcaggttc tttcttggca ttgttcttag
     7501 ataactatga attcctagga tctgctaaac aatttatcca tgtagcagct gcttatgtcc
     7561 atgaagattt ttatggagaa aaactaggag tcgcttatga agatgaaaaa atgggcaaat
     7621 tgacaatgaa tgctggacta tttgcttttg aagaaaatgg tacagaggaa gcgaacttca
     7681 tcaatatgaa tttccgtttt ccaaaaggtg taacagtaga cggattgcaa agtgacatcg
     7741 aacaaacagt ggggcaagaa ggcgcaacag ttactcgagg tgctcgcgta atggaaccac
     7801 attacgtacc aatggatgat ccattggtgg ctacattatt gcaagtctat gaagaccaca
     7861 ctggagaaaa aggctacgaa caaatcatcg gtggcggaac ttacggacgt ttgttgaaac
     7921 gtggcgttgc ttatggagcg atgttcccag gatatactga tacaatgcat caagcaaacg
     7981 aatttatgag tcttgatgac ttgttcagag caacagcaat ctatgcagat gccatctatc
     8041 gtttggcgaa ataaaaatac taaaaaa
//
LOCUS       DACDAF010000109         7844 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.115, whole genome shotgun sequence.
ACCESSION   DACDAF010000109 DACDAF010000000
VERSION     DACDAF010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7844
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.115"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(39..2150)
                     /locus_tag="IVZ69_002445"
     CDS             complement(39..2150)
                     /locus_tag="IVZ69_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP8184477.1"
                     /translation="MEGIMENKIHCTTGRVITLVLFLFLLLFARGTAVQALEKVDPSQ
                     IKENNNLVLYHDSDSLRNIEVTGINGFKILDEYSTKKQKVLAWPKVKDLKSTSKIVAH
                     YQKVGTYLGKEIDCDVTFSNFVAHAGVNQDGLAKTINGKKYYNYLLFDKNIYRGFFMQ
                     SINVMNAKLEFKYAGTKTKVALSEPQPEIQSKMRSMRAAGIDLNDTFLSIYSLNGQYQ
                     QRVSWYNDNNESVGERNIDMREFVGYEKMGSLPYFVTTDTACAEYKAPALSTNNLTSK
                     VVGGRAEKAYSSNDHFTDVVGADTYHRSGVTYTLQGASPTFMIGANTNSMMFSFDTAL
                     LWTPQPSKPTKEVFNKANTEEAAHNIDKKVIPQGSDVYYHIHQKFDALTVNTMNKYKS
                     FKITDTFDSKNFDMVSDGKNYDGALWYVEANGTWKKADTGGKLTVSGNTVTYTASDSF
                     LANAANYGRDYILQLHMRAKNDAKGIAPNVATVTFNNDPNKGTQKTNTVENYFSLKPN
                     KKVEQDGKDVDGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDIASDHYKQFSIQD
                     PVEDRLTYKEGSARVIDMSTGKDITSEGTLTYDSNSRTLKWEASADFLSKNLLDGREI
                     QLIFTAKTPLNEELDIDNQAKVSVESIEKATNVVTIGVKPNLPQIIVPKTGSNHLVLT
                     VIGSILFLTLASLGYVVLKLK"
     gene            complement(2439..3263)
                     /locus_tag="IVZ69_002446"
     CDS             complement(2439..3263)
                     /locus_tag="IVZ69_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184478.1"
                     /translation="MNKRKWLFVCVAALFSTVAYSQLSFADSSDSSTTQTIDNSITAP
                     SETDSSENTTEETADSNISFTESTNPTSESSSETSEKPQDVEDTQVIKQAIHIQKIIS
                     SNQINNQGSQVAQQEGINGAKFIVYDITNILEEMSQDDNEKNQSVEIIESKLKDRAKK
                     LSYDQLKKVAEGETKTIDDQEGVIEFSIEVPANKKQAYYIVNESSPENISNSEDIVLL
                     TPVSNEKGEFLTDVWLYPKSEKSEPKEEIKKVVSTGVKKNFFENCWEFFAQLFFDN"
     gene            complement(3260..4015)
                     /locus_tag="IVZ69_002447"
     CDS             complement(3260..4015)
                     /locus_tag="IVZ69_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HAP8184479.1"
                     /translation="MIIRKPPKRRVMHKLMIFFWLLSAVAVYLIPVVETNVAKFQQQQ
                     RILAIENLEKTDSSLDVAKIELGDPVGVLTIPSISLKLPIYDGTSDKILENGVGITEG
                     TGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGQKFFIKVNEEQHAYQIYRIEEVK
                     AEELQKNYLDYLMPEKDQDRITLMTCTPKGVNSHRFLVYGERVSFSKEDLKLQKKAKN
                     RKSISLDWRLALLFAFFCVPIIFIYKKIRRRSE"
     gene            complement(4028..6004)
                     /locus_tag="IVZ69_002448"
     CDS             complement(4028..6004)
                     /locus_tag="IVZ69_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HAP8184480.1"
                     /translation="MAINRYVKKAGMLVGMLGIIAGCFQGYQVHAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGGLSAVVYFKKKA"
     gene            complement(6057..6728)
                     /locus_tag="IVZ69_002449"
     CDS             complement(6057..6728)
                     /locus_tag="IVZ69_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HAP8184481.1"
                     /translation="MKKWLFGFLGVTLIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPGYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            complement(6788..6997)
                     /locus_tag="IVZ69_002450"
     CDS             complement(6788..6997)
                     /locus_tag="IVZ69_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184482.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKTMKQKHLKRLSVAQYINDMQLT
                     GKEKACLLGSMKNFEQLRRTYRIHF"
     gene            complement(7064..7303)
                     /locus_tag="IVZ69_002451"
     CDS             complement(7064..7303)
                     /locus_tag="IVZ69_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184483.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKEVFKALSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            7713..>7844
                     /locus_tag="IVZ69_002452"
     CDS             7713..>7844
                     /locus_tag="IVZ69_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP8184484.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT         2163 a         1595 c         1197 g         2889 t
ORIGIN      
        1 aaagaaaaca aggctgattc tcagccttgt ttttatattt atttgagttt taaaactaca
       61 tagcccaatg atgctaaagt aagaaataat atacttccaa taacagttag cactaaatga
      121 ttcgatccag tttttggcac aatgatctga ggtaagttag gttttacccc aatcgttact
      181 acattagttg ctttctcaat actttctact gaaacttttg cttggttgtc gatatccaat
      241 tcttcattca aaggagtttt agctgtaaat atcagctgaa tttctcgtcc atctaaaaga
      301 tttttactta agaaatcagc ggaagcttcc cacttcagcg ttcttgaatt gctatcatag
      361 gttagtgtac cttctgaagt aatatctttt cctgtactca tatctatcac tcgcgcagaa
      421 ccttctttat acgtcaaacg atcttccact ggatcttgaa tactaaattg cttgtaatga
      481 tctgaggcaa tgtctacacc ttttgtatgc catttttgtg tgactagata ttgtacttca
      541 gatcctgcat ttaaaggagc tgtaggcgtt ccttttttac catcatttcg accatcaaca
      601 tctttcccat cttgttccac ttttttattt ggtttaagag agaaatagtt ttctactgta
      661 tttgtttttt gtgttccttt gttcggatca ttgttaaacg ttacagtagc cacatttggt
      721 gcaattcctt ttgcatcatt ttttgctctc atatggagct gcaaaatata atccctaccg
      781 taatttgcag cgttagctaa aaagctgtca gaagcagtat aagtgactgt attacctgat
      841 acagttaact ttcctcctgt atcagctttt ttccaagtac cattcgcttc aacataccac
      901 aatgcgccat catagttttt cccatccgat accatatcaa aatttttgct gtcaaaggta
      961 tcagtgattt taaatgattt gtatttgttc attgtgttga ctgttaatgc atcaaacttt
     1021 tggtgaatat gatagtaaac atctgatcct tgtggaatca cttttttgtc aatattgtgt
     1081 gctgcctctt cagtattagc tttgttaaac acttcttttg taggcttcga tggttgtggt
     1141 gtccatagca atgcagtatc aaagctaaac atcatactat tcgtatttgc gccaatcatg
     1201 aatgttgggg aagcgccttg aagcgtatac gttacaccac ttctgtgata agtatcagct
     1261 cctacaacat cggtgaaatg atcattcgag ctataagcct tttctgcacg tcctcccact
     1321 acttttgaag ttaaattgtt tgttgataac gcaggagctt tgtattctgc acatgctgta
     1381 tctgttgtga caaaataagg taagctaccc attttttcat acccaacaaa ttctctcata
     1441 tcaatattac gttcaccgac agattcatta ttgtcattat accaagacac acgttgctga
     1501 tactgtccat ttaaactgta aatggataga aatgtatcgt ttaaatcaat accagctgct
     1561 ctcatcgatc tcatttttga ttgaatttct ggctgtggtt cactcaaagc tacttttgtt
     1621 tttgttcctg catacttaaa ttctagtttt gcattcatga cattgattga ctgcatgaaa
     1681 aatcctcgat aaatattttt atcaaagagc aaataattat aatacttttt gccattaatt
     1741 gttttagcta atccgtcttg gttaacccca gcgtgcgcta caaaattaga aaaagtcacg
     1801 tcacaatcaa tttcttttcc tagataagta cctacttttt gataatgggc aacgattttt
     1861 gacgtacttt tcaaatcttt gacttttggc caagcaagta ctttttgttt tttagttgaa
     1921 tactcatcta gtatcttaaa tccattgatc ccagttactt cgatatttct caatgaatca
     1981 ctatcatgat aaagcaccag attattattt tctttgattt gactcggatc aactttttct
     2041 aaggcctgga ctgcagttcc cctcgcaaaa agaagaagga acaaaaacaa cactaaagta
     2101 attactcttc ccgtagtgca atgaatttta ttttccataa tgccctccat ctaatatttt
     2161 tttaaacgat cgtaagcttt tcattctttt tttcctaata cccacgttac caatcctgta
     2221 agaagaacca aactaaccat aaaaattgga ttgatcaaga gctttttaat cacctctaat
     2281 ggcatggaag cacattgaat gtttagaaaa tgaatgaaca atcgttgata tcttggataa
     2341 attgataatt gagaaaaaat taaaccgcaa cacaatattg ttgcggctaa aaaggataga
     2401 ttaaaaacta atattcttat tattttcatc atttcatcct aattatcaaa aaataattga
     2461 gcaaaaaatt cccaacaatt ttcaaaaaag ttcttcttta caccagttga cacaactttt
     2521 ttaatttctt ctttcggctc tgatttctct gatttagggt ataaccaaac atccgtcaaa
     2581 aattcacctt tttcatttga aacaggtgtc aataaaacaa tatcttcact gtttgaaatg
     2641 ttttcagggc ttgattcatt aacgatatag tatgcttgtt ttttgtttgc aggtacttca
     2701 atggaaaatt caatcacgcc ttcctgatca tcaatcgttt tggtttctcc ttcagccact
     2761 tttttcaact ggtcgtatga aagttttttt gctcgatctt tcaattttga ctcaattatt
     2821 tctacagatt gatttttctc attatcatct tgtgacattt cttctaagat attcgtgata
     2881 tcgtagacaa taaacttcgc gccattgata ccttcttgct gggctacttg actgccttga
     2941 ttgttgattt gattcgaaga aataattttt tgaatatgaa tggcttgctt gatcacttgc
     3001 gtatcttcta cgtcttgcgg cttttctgaa gtctctgaag aactttctga cgttggattc
     3061 gttgattcag taaagcttat atttgaatct gccgtttctt ctgtagtatt ctccgaactg
     3121 tccgtttcgc ttggtgcagt aattgaatta tctattgttt gagtggtact actatcactg
     3181 ctgtcagcga aagacagttg cgaataagct acagtagaaa agagagctgc tacacaaaca
     3241 aacagccatt ttctcttatt cattccgatc tcctccttat ttttttataa ataaaaataa
     3301 taggaacgca aaaaaaagcg aatagcagtg ctaatcgcca atccaatgaa attgatttcc
     3361 tattttttgc ttttttctgt agttttaaat cttctttact gaaggaaact cgttcaccat
     3421 acactaaaaa gcggtgtgag ttgacacctt ttggtgtgca tgtcattaac gtgatcctat
     3481 cttggtcttt ttcaggcata agataatcta aataattttt ttgtaattct tctgctttaa
     3541 cttcttcaat tcgataaatt tgataggcat gttgttcttc atttacctta ataaagaatt
     3601 tttgcccttt ttttactgaa ggcaaatcat cgaaaagatt atctttataa agtccactgt
     3661 gccccgcgat taaaggattt ttaccgtttc ctcctgtaat atcgccagtt ccttccgtaa
     3721 tccctacacc attctctaaa attttgtcgg aagttccgtc ataaattggt agttttaaag
     3781 aaatacttgg aattgtaaga acaccaacag gatcgcctaa ctctattttc gcaacatcca
     3841 aagaagaatc tgttttttca agattttcaa tggctaaaat tctttgctgt tgttgaaatt
     3901 tcgctacatt tgtttccaca actggaatta aatagactgc tactgccgac agcaaccaaa
     3961 aaaatatcat cagtttgtgc atgactcttc tttttggggg cttacgaata atcattagct
     4021 gatccttcta ggctttcttc ttaaagtaaa caactgcaga aagtccccct gctcctagca
     4081 acaagcaaga gatcaatacg taagattgga aaccgttgct accagtcatt ggtacggaag
     4141 ctttttgatt atttttgatc gtgattcggt tttcttcttt gtatgaatct ttgtctactt
     4201 tgaaagagat ctcttttgtt aatttttgat agttttcagg agcttttgtt tcttccagtg
     4261 agtaatctcc ttcagttaaa ccagtgattt caaaatgacc ctctttatct gattttagga
     4321 ttgctgcatt tgctacatcg tctacccaaa ctgcttcttt gacaccatct ttatctgtat
     4381 cagtaagtcc accgtagtac ttaccttctg cattcttagc tgcaaattct gcgccttcaa
     4441 gcggtgttgc tttgatacct gttccaaata ggccgctatc gacttttaag aattttgcgc
     4501 cataagtcac aacgtcagct ttcgtttttt cgtggtgttc ttcctgatta aatggattat
     4561 tgttataaac gaaatccacg ctatttgtta atggatttgc gatttcagca ctatcattca
     4621 caaacatgtt ataagtcatt tttagatctt gaccatgtaa attcgcaact gtatcactta
     4681 cttgtccatt atttacgata aaatcgatca caaaaccact atcagaattt tcgattttat
     4741 agtcagtatt ttcttttaat acgactgaac catcattatt tgttacttta atatctgctt
     4801 tttcagcaac ataagaaagt cctttacctg ctgtatctcc ccatttaaat acactgtaag
     4861 gagaagtttc gcttttcaca ccgtttactg tgataccgtc tgcgccacct gcaatgtctg
     4921 ttggaatatg aatcgttcct tgataattta ctgcgtcacc aatttggaaa gaatgttctt
     4981 gtcctgttcc atttgttact gttttatcga tcactggtgc tttatagttt acgtatgaag
     5041 cttttaagtc acttgtcacg ccatcattcg taatttcaaa ggttaattta ttgtgcgcat
     5101 cgttgcgagc gtctgcgcct aataaatatt gatctgctgt tggttcttga tctgatccca
     5161 ctacaacttc cgaaggaact tccacaaaat agtattttcc taacgtcaaa tcagtcgcag
     5221 tcagctttcc ttgatcatcc gatacaagat cacccaattt tgttcctttt ccaggttcgc
     5281 ccttgtataa ctcaaatttt gcccctttta aaagggtttg tttgctttgg tctgcgccat
     5341 cgtcaccaaa tttcgttaat tcaaaactca acttagaaac aatgttctta ggatacaaat
     5401 gaatattttt taaaaatcct gatcctgttt tatctgtcat tggcgcaatc acaaccattg
     5461 gttttgcttt ttgtgtgact aatccagcag cggatttact ttcataaacc acatatacat
     5521 tccctttgga attgacatag gctggttgat cagtaaaagt gatctcacca ttttcatcta
     5581 cagctgaagt aattttgttg gttgcattct tgacgtactc actgttagat cccttgtctt
     5641 ctacatcttg tacaatctcg tccactttcg cgttggttag atcagaatct tctctcggta
     5701 atacttgatc cgtaatattt cctaacgtaa actcaacatc accataatct gccttgttgt
     5761 atttcgttac acctgtagga tattgatcgt gcgtataacc atcgtttttg atcccgtcaa
     5821 tatcaacatt caattgcgtt ccttgatcgt acattaattt atgaaccgtg atattgacct
     5881 tctctggtgg tgttttttgc gtgacatctt ctgcatgtac ttgatacccc tgaaagcagc
     5941 ctgcaatgat tcctaacatt ccaacaagca ttccagcttt ttttacatac cgatttattg
     6001 ccatttttta ctctcctcat ttcatatttc aacgactcgc gttgattaaa accttgttat
     6061 tgtagctctc cctgtaccac gtatctttct tttccttgtg acgtataaac acaagtaaac
     6121 aacgttaata agggtttctc tcctttcttt ggcaaagaca agaaagagtt ctcttcagga
     6181 acgccatcga ttaatttaaa gtacccaggt acgataaatt tacgcgttac cttgtaacga
     6241 tagacgccat cgttactaac taagtccatc acctccccta atgacaactt ttgaatatca
     6301 gaaaataaaa cacctggcat ttccatgtta tgacctgcta ggacatagtt tcctttgccc
     6361 atttcggcat cttcataaaa ataagtagcc gctccaagac tcaaagtgta ttgatttgcc
     6421 cctttaaaaa ttggcaatgc taaaccaagt gcaggaatct gaatttgtgc aaatacttgt
     6481 ttattgacgc ccatttcgat tgcttctttt tgtatggaca acatttgccc caaagacata
     6541 tcattattga cgttcgttgc atcctcctta taactctttg catgtgcatt gatttgatct
     6601 acgggcatct ttttttctat attttgctta aacacctctc cttcatgttt ttggtagcta
     6661 acatagccaa acacactgca aaagacgatt aaagtgactc ctaaaaaacc aaataaccat
     6721 tttttcatcc atctgcctcc tttcagacaa aacaaaaaaa ctttttctca tttccataga
     6781 aaaagtttta aaaatgaatt ctataagttc gtctcaactg ttcaaagttt ttcattgaac
     6841 ctaacaaaca agctttctct tttcctgtta actgcatatc attgatatat tgcgcgacag
     6901 ataatctttt aaggtgtttt tgcttcatcg tttttagtaa cttttcttcc atttctttcg
     6961 acactttttt tctgttttcg atttcttcat aattcatgag ttttcctacc ttccttgttt
     7021 tttgcaaaaa taaaaaagcc tatgatcaca tacgctctac acttcagtct tgggttatct
     7081 ttttctttcg tttaattact ggccgtgctg gtttcaaatc cttgattcca ttatgggttc
     7141 tccaataatc gaattctttt cgcaatcttt ctttttccat atctgttcct ttagataagg
     7201 ctttgaatac ttctttaggt gaataaccac gagctaacag ctgtacatac cttccttttg
     7261 tcaaagtatc catatccatc gcctctaaaa ctggtcgcgc catctactat tcctcctcgt
     7321 aaaatatcat ttgtctaata gtttttattc aaaatgtttc tagattataa aatttattga
     7381 ataacacatt cctaacggaa tttgtttcga tattgtgtga tttctcagag tacaatggat
     7441 gtatggaaag gatccaacgg gaatttgcta tttcctcctg tagcgtttgt ctaccctgtt
     7501 tagtctgtta cccgaaccac tgttatcact accaactcat tagctgtttc gataatggac
     7561 tagactttca aatagtagtt tggaaggcag cttctagctc ttttatcacc gtattctatt
     7621 aggcgaggtt gtggctatac agtgagtttc tgggaaatcc cacagtatcg aagcattttc
     7681 caaaatttat atcgaaagga ggtccttctt ccatgaaatt atttgtcggt attgacgtta
     7741 gctctgaaaa actagatgtt tgttttttaa cagacgacaa tcaattgtct atcttatctg
     7801 aaatctctgt tgccaatgac atcgaaggtg cttcattcat acga
//
LOCUS       DACDAF010000110         7609 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.116, whole genome shotgun sequence.
ACCESSION   DACDAF010000110 DACDAF010000000
VERSION     DACDAF010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.116"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            35..811
                     /locus_tag="IVZ69_002453"
     CDS             35..811
                     /locus_tag="IVZ69_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HAP8184485.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            826..1029
                     /locus_tag="IVZ69_002454"
     CDS             826..1029
                     /locus_tag="IVZ69_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8184486.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            1045..1383
                     /locus_tag="IVZ69_002455"
     CDS             1045..1383
                     /locus_tag="IVZ69_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HAP8184487.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            1370..1549
                     /locus_tag="IVZ69_002456"
     CDS             1370..1549
                     /locus_tag="IVZ69_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184488.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(1592..2062)
                     /locus_tag="IVZ69_002457"
     CDS             complement(1592..2062)
                     /locus_tag="IVZ69_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184489.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            2149..2847
                     /locus_tag="IVZ69_002458"
     CDS             2149..2847
                     /locus_tag="IVZ69_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HAP8184490.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            3025..3366
                     /locus_tag="IVZ69_002459"
     CDS             3025..3366
                     /locus_tag="IVZ69_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184491.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            3359..4030
                     /locus_tag="IVZ69_002460"
     CDS             3359..4030
                     /locus_tag="IVZ69_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HAP8184492.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            4036..4722
                     /locus_tag="IVZ69_002461"
     CDS             4036..4722
                     /locus_tag="IVZ69_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184493.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            4725..5474
                     /locus_tag="IVZ69_002462"
     CDS             4725..5474
                     /locus_tag="IVZ69_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8184494.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            5486..5755
                     /locus_tag="IVZ69_002463"
     CDS             5486..5755
                     /locus_tag="IVZ69_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184495.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLNELEQV"
     gene            5917..6219
                     /locus_tag="IVZ69_002464"
     CDS             5917..6219
                     /locus_tag="IVZ69_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184496.1"
                     /translation="MDKKAAMQRIIELTYSEDWQNDKEAASEVMRLGRAMWADKSNKP
                     RPRKIAIWHGDKLLVIGTAEQLASLTGLHEKIVRKRARCGYTDAKKRTFRYVEESS"
     gene            6216..6377
                     /locus_tag="IVZ69_002465"
     CDS             6216..6377
                     /locus_tag="IVZ69_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HAP8184497.1"
                     /translation="MTTEEVIQMRIRSLQREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIHRLEE"
     gene            6374..6679
                     /locus_tag="IVZ69_002466"
     CDS             6374..6679
                     /locus_tag="IVZ69_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184498.1"
                     /translation="MSVDKKAAMKRIAELTKSESWQEDKEIVAEVQKLGKSMWTEKPK
                     RRTPRKIAIWHDDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            6679..7035
                     /locus_tag="IVZ69_002467"
     CDS             6679..7035
                     /locus_tag="IVZ69_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HAP8184499.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILEEYLR
                     RTANDKKTRSIQHGFI"
     gene            6995..7240
                     /locus_tag="IVZ69_002468"
     CDS             6995..7240
                     /locus_tag="IVZ69_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184500.1"
                     /translation="MIKKLVQFSMDLYDIESGATLSVESDHLIINFGGKRQIILWVVD
                     DVLFPEIVHDFEESKAVEFEIVKKVMELIEKYEEDSE"
     gene            7237..>7609
                     /locus_tag="IVZ69_002469"
     CDS             7237..>7609
                     /locus_tag="IVZ69_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HAP8184501.1"
                     /translation="MIPKFRAWDKRKNVMRDVAVLHFTKNGKTNFIEYWINPTELKSY
                     HVRNIDLMQSTGMKDKNGVDIFEGDIVLVSVRNGFDYLDNKVCIVKNSIDYSGLVCAT
                     VDEDLEYQIFNTELFEEYTYEV"
BASE COUNT         2868 a         1156 c         1607 g         1978 t
ORIGIN      
        1 ttgtttacga atataaaaga aaggaatgag aaatatgaac acaccgcaaa tttttaattt
       61 cgaacaaaac gaagttcgga caattttagt aaatgatgaa ccatattttg taggcaaaga
      121 cgttgcgagt gttttgggtt attcaaacac taaagatgct ttgtcgcggc atgtagattt
      181 ggaagataag atggggtcgc gaatcacgac ctcaggtcaa tcaagagaga tgacaatcat
      241 caacgaatct ggtttgtaca gtttaatctt aaaatcaaaa cttccctctg ccaaaaaatt
      301 taaacgttgg gtaacaagtg aagtgttgcc agcaattaga aaacatggag gttatctaac
      361 tccagaaaaa gtagaagaag ctttgcttaa tccagataca atcattcaat tagcaactca
      421 actaaaagaa gaaagaactg gaagattaat cgcagaacaa aagattgcag agtacgaacc
      481 taaaatctcc tatttagata gcatattatc ttctacagat tcagtaacaa ttagtcagat
      541 tgcagcagat tatgggatgt ctccacaaca gatgaataaa ttacttcata aactaggtat
      601 tcagaaaaaa gtcggtaacc aatggttatt gtgcaaaaaa cacatgaacc aaggatacac
      661 aaaatctcat acaactgaga tcccgaaagc cgatggtggc actaaaattg taatgaatac
      721 caaatggaca cagaaagggc gtctatttat ctacgaatta ctaaaaaaag aaggatatta
      781 ccctcaaatg gatttagagg aaattggtta gaaaggagtt ttagtatgac tgacattgca
      841 gaaatcactc aacgagatag agaaaaaatc aaagaatatg tcgaaagttc aaagttctta
      901 acttacacca tgcttgctga aagatttgga attagcaaaa gctacttatc tttaatttta
      961 aacggtaaaa agacttctgc agaagcaaac agaattatag attcgattat cactatgtac
     1021 gaattgtaaa gggaggaaca gctaatgcaa tatctagaag caaaaatccc aattccagaa
     1081 ggctatgtaa ttatctccca agtggattat gaggagttaa aaaaagctga tgatactggt
     1141 agatggatga cgttgccaga agtgctagaa cggattaaca gaaaatatga ttggtttact
     1201 tctagagttt taaagaaccc aagatataga aatattatcg atatcgagaa aaacaaaaat
     1261 ggatttgtct attatccagt tgaaggaaga gacacatatc tatttttaag aagtaaaaca
     1321 cttgaatttt tagaaacaaa tttttcggaa atcttaagga ggcaagcgga tgggaaaatt
     1381 taatagagcg ctagtgttca gcgcaccgct aatcatctac gctttaggac tttggggaag
     1441 caggcaagcg ttgataggaa cgattgttta catggtttgg atttttatgg ggcttgatga
     1501 agctgaagct gagtacagag cgaaaaagcc aaccgagggg gctgactaaa aatgaataga
     1561 aaagagaaac tagaatgtat attactatta ctcagtttaa ttctttcact aatttctcta
     1621 ttgggaagtt tgtatttttg atatcaacaa ttttgtggat ttgggttcta tttagagtaa
     1681 atatcatttt tgtttggtga ttaaggagtt tattaaaatt aattttccct acttcaaatg
     1741 caaggtaaca agatatagca cttttaggag gaatatttag cggtacagct tcagagtata
     1801 ttctattatc atcgactgat cctcctttag caattaattt cttaaatgga gtagctgacc
     1861 atctgcggtt taagttagcg gatgaaagtt ctaaattaac taacatagct ggttctgttg
     1921 aatagttaga aatgattact tttgtataaa tcatatctgc agcgaagtaa gaagcattaa
     1981 gttcaacttc tagttgaggg cgcattcctt ttatttttat ccctgttaaa aacgtactca
     2041 atataaaact tattattgac atccattgaa aaattgttaa gtgaaaaaaa ttcaaaataa
     2101 acaccaccag tttttaacta aattatacca aaaaggagag aagaaataat gcaagaatta
     2161 gtaattttga aaaataaaga agctgtgact acgagcttac aagtggcaga aagcttcgag
     2221 aaaaaacatc aacatgtttt aagagatatt gatgcactaa aaaaagatgt gtccaatttt
     2281 ggacagatgt ttgtagaagg taatgaacca gattcatatg gcagaaatcg acgagttttc
     2341 ttcattagta gagatggatt tttcttgctg gctatggggt ttacaggaaa gaaagctatc
     2401 tacttcaaac aaaaatacat tgaagcattc aacgaaatgg aagatgttat tcgcaagaat
     2461 actgttcctc aaacaattga agatatgatg atctatcaat tagaagaaat gaaagatgtt
     2521 aaaaaagatg tttccatgct taaagatact atgcgaatta gcggacaaca agagtttgaa
     2581 attaagcaaa aaggaaatat gaaagttatg ggagttctag ggggaaaaga aagccgagct
     2641 tatgaagaaa tcagcaaaaa agtattctca aaattttggt ctgaatttaa acgtaccttt
     2701 tcaatcccaa gatatggcga gttacctcgt aagagattcg atgatgctgt ttcatttatt
     2761 gaaatgtggt tgccagaaac tgcgatccgt atggaaattg atcaactgaa cagacaacag
     2821 agactttttg gtgatgacaa tgaatagagc tgaagcgcta agaataggga cggcaattgc
     2881 taattgctgg tggaaatact ataaaccaat catcctaagc caacaacata ttgacaagca
     2941 aaaagcatgg caacaaataa aaaagtgact ccgccggcaa gcaaagagtc acaaagaaaa
     3001 cacatcataa ggagatttta gcatatggaa aaagaacttt ccactctaga tcaatatttg
     3061 attgatcctg attggggcaa gccgaaaatt gaggaaacaa gtggtcgaaa aatcagacga
     3121 aatcttttga cgaatgaaga actagcttgg gatcaagatg atttaggcaa ccatgtaact
     3181 atttgggatc atgtttatct tatccatcta tcgaagcatt cgaataaacc tgaatatatt
     3241 tacgtcatcg aagatggctt gattgatgcg ctagaagagt acgacagaga taacttgatt
     3301 gatatctctt attacggacc aggtaagaaa tacattgctg aaatggaggc agaatttgat
     3361 gagtgaaatc aaagggacaa cgaactttga aaaacttttt agtcgtaagt taaataaaat
     3421 tctcaagaaa aaaggaaatt ttgattattt atcttgggct cacgcgtggg agattatgaa
     3481 aaagaatgat ccacaggcaa cggtaactat taatgagtac aaacactaca gggttgtttc
     3541 tggaactcat caagactttc ttgttgagga atataaacct tttcttatgg atgaaactgg
     3601 gacttatgta tctgtctcag taacggttaa aggacacacg gaaaccgaat tatttcctgt
     3661 tttagattat cgaaaccaac cagttgttaa accaaatgca atgcaaatca ataactcatt
     3721 gaagcgatgc tttgtgaaag cattggctct acacggactg ggattatatg tatttcaagg
     3781 ggaagatatt ccaacaccac ctagaatcga tacaaagaaa ttaaacatgc tagagacgat
     3841 tctagaagct ttcaatgagc agatgggtaa agatatgacc aaaaccttaa tcgaatatgt
     3901 taatgagcag acagataaat tagggctctt agctgataac gttgaaacta ttgaacagtt
     3961 aagctatgag caatgtgcct tgatggagcg agcaatagca gctaagagaa aagaattaga
     4021 taagaagtga tatgagtgtt taaaccatta atcgattcat attcagcggt tctgaaaaag
     4081 ttcaaaggaa aagacataag cgcaaccatc aatgaggaag tgaacattga tcgactaaag
     4141 acgatgtatg acggctacga tggtgatcga gtcattgaaa ttcgttttat tgatcctaga
     4201 cgtttcaccg tacagcaacg aaacttcatc tatgcgctga taggcgatat ttttatcgat
     4261 acaggcatgc caacggactt ctggaaggaa ttcttctact ttcgttttga aggtgtcaca
     4321 gggcgcaaaa taagcctgaa agacgaatcg aatacaactg tgagtgatgc caatgtctta
     4381 gcaaatatca tcttagattt catctttgaa catcatattc ctttcaaaga aggctatgag
     4441 attttacctg cgaatcaaga atattacttc tacaaatgca tcacaaaaag agtctgctgc
     4501 atctgtggca aaacaggagc tgacatcgat cactttgaca aagcgctagg aagacgaaag
     4561 cgcaaagaag ttgatcatgc agagtacaca tttgcagcac tctgcagaat ccatcacaca
     4621 gagaagcaca aaataggtgt gattaatttc aaaaataaat atcaaatcaa agggatcaaa
     4681 ttaaaccaga aaacaatcaa aaagttaaat attggagggt aaaaatgaca gaacatcgaa
     4741 gttattatgc gattatacca gccaacgtaa ggtacgacaa aagacttaaa ccaaatacta
     4801 agttgttata cggagagata acggccttgt gtaatgaaag aggcttttgt tgggcaggca
     4861 atgagtactt tgcagattta tatggtgtga ataaagagac catatcgcga tgggtaagtg
     4921 atttgattaa gtttggatac ttgaatcggg aaatcattta caaagagggt accaatcaaa
     4981 taatcaatag gtacctacga attaatcaat accctattga cgaaaaacgc aataccccta
     5041 ttgacgaaaa agtcaaagat aataatacat ctattaataa tacatttaat aatacaaaag
     5101 aatatataag agagttaccg ccttcgaaaa aatcgaaggc taagcccgtc cgtcataaat
     5161 acggagagta taaaaatgtt cttttgtcag atgagcagat ggagaaactc aaaacagaat
     5221 tccctaatga ttaccaagag cgaatcgaac gactgtcaga gtattgtgaa tcatctggta
     5281 agacttataa aaactatttg gcaactattc gaagttgggc aaggaaagaa aaaagtgaac
     5341 ctaagaacgc aagcagtgga tacaagcgca caggaagacg agagaagctt cctgaatggg
     5401 caatcgacca agaagcctat ctcaagaaaa aagcgctaga acgagctaat agacaatcaa
     5461 aagcaccatt ctaagaggtg gaaaaatgaa gatcgattat ctagaactaa ttaatgaaat
     5521 agcgaattat aaaaagggcg aggaattaga cgtcctgaga gacgtatatg atcaactcga
     5581 agaagctgga attgaaggaa ttaagaatga tcgttcgagt tggagtaagc tcagatacta
     5641 tttcgcactt tatatcgata caacacaatt aagaaattta gcatatacca aattactatt
     5701 tgttgattgt gttaaaggct tgcaaaaaca tcttaatgaa cttgagcagg tgtaatcaga
     5761 tggacctaaa gacatttaca gcacagattg aactaatgca tcaagaagct ttaagacaaa
     5821 gtgtatcgta cgaagacaag tggctcaaca cgttccatgg cggacgtgag agcgcacttg
     5881 atcaagtact caaattactg aaaggagaat gtcgggatgg ataagaaagc ggcaatgcag
     5941 cgaattatcg aattgactta ttcagaagat tggcaaaatg acaaagaagc tgcttcagaa
     6001 gtgatgaggc ttggaagagc gatgtgggca gacaagagca acaagccaag accacgaaaa
     6061 atcgcaattt ggcacggtga caaacttcta gtgataggga cagctgaaca gttagcaagt
     6121 ctcacaggct tgcacgagaa aatcgtgagg aaaagagcaa ggtgtggcta cacagacgct
     6181 aagaagagaa cgtttagata cgtggaggaa tcatcatgac aacagaagaa gtgattcaaa
     6241 tgcgtattcg aagccttcag cgtgagattg acgatctgga acgaacaaag gcagtgatgg
     6301 tcaatgaaac ggcgagaaag gcaatcgatt tgcacataga gaatttaaga agggaaatcc
     6361 atcgattgga ggaatgagcg tggataagaa agcagcaatg aaaagaattg ctgaattaac
     6421 caagtcagaa tcttggcaag aagacaaaga aatagttgca gaagtccaaa agctcggtaa
     6481 atcaatgtgg actgaaaagc ccaaacggag aacgccgaga aaaattgcaa tctggcatga
     6541 tgaccgaatt ttagtaacag gtactgctga acagttatct gaaattactg gattaagcaa
     6601 aaacattatc tgggatagag ctaggagctt atggattgat tcaaaaggac gacagtttag
     6661 gtatgtggag gagagataat ggatctcatt acacaataca gtgacatcat cctcaagaaa
     6721 atcatgatga agattcagaa agataaaaaa tcaaaagaac gagctgaatt agttaagtta
     6781 gaaatggctg aaacaggagc aggagtgcga agtagcaggc attggaaagc agcagcaaac
     6841 attgaatttt attacaacga aattcaaaaa gggttcgatc agatgcgtga gctggatcgg
     6901 caaacaaatt ggagcaagaa acttcatcaa gatcgtttca aatttgtaga gaagtataaa
     6961 gaaatattag aagagtattt gaggaggaca gcaaatgata aaaaaactcg ttcaattcag
     7021 catggattta tatgatatcg aatcaggagc aacactatct gtggaatcgg accatctaat
     7081 cataaatttt ggtggaaagc gccagattat tttgtgggta gttgatgatg tactgtttcc
     7141 agaaattgtt catgatttcg aagaatcaaa agcggttgag tttgaaatag tgaaaaaagt
     7201 aatggaattg attgaaaaat acgaggagga cagcgaatga taccgaagtt tagagcgtgg
     7261 gataaacgaa agaacgtaat gagagatgta gccgtcttgc attttactaa aaacggcaaa
     7321 acaaacttta ttgaatattg gataaatcct accgaattga aatcatatca cgtgcgaaac
     7381 atcgacctca tgcaatccac aggaatgaaa gataagaatg gtgtggatat atttgaaggg
     7441 gatatagtat tagtcagcgt gcgaaatggc ttcgattact tagataataa agtctgtatt
     7501 gtcaaaaatt caatagatta ttccggatta gtttgtgcca ctgttgatga agacttagag
     7561 tatcaaattt ttaacacaga gctgtttgaa gaatacacgt acgaagtca
//
LOCUS       DACDAF010000111         7597 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.117, whole genome shotgun sequence.
ACCESSION   DACDAF010000111 DACDAF010000000
VERSION     DACDAF010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7597
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.117"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(135..425)
                     /locus_tag="IVZ69_002470"
     CDS             complement(135..425)
                     /locus_tag="IVZ69_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184502.1"
                     /translation="MGEKKIKGAGILLVMSKALFLLPCTFMFIVLCYFKRRKKWCWID
                     VLLFLPFFPLIYFLEEIWDDMACDSAFLFSHSLGLMISLTIFAIVLFFLNKK"
     gene            complement(543..803)
                     /locus_tag="IVZ69_002471"
     CDS             complement(543..803)
                     /locus_tag="IVZ69_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184503.1"
                     /translation="MGVDHLIVLSKLLFWIPFIIMTSAFFYLFKRPNKYLLLSACPMI
                     YFIHKIRGFYYYDSGISLFCYEIGLLASAIFFIFVLEYFRKK"
     gene            complement(940..1353)
                     /locus_tag="IVZ69_002472"
     CDS             complement(940..1353)
                     /locus_tag="IVZ69_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HAP8184504.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1809..2294)
                     /locus_tag="IVZ69_002473"
     CDS             complement(1809..2294)
                     /locus_tag="IVZ69_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184505.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2433..2648)
                     /locus_tag="IVZ69_002474"
     CDS             complement(2433..2648)
                     /locus_tag="IVZ69_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HAP8184506.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2872..3672
                     /locus_tag="IVZ69_002475"
     CDS             2872..3672
                     /locus_tag="IVZ69_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP8184507.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3691..5559
                     /locus_tag="IVZ69_002476"
     CDS             3691..5559
                     /locus_tag="IVZ69_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HAP8184508.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5552..6043
                     /locus_tag="IVZ69_002477"
     CDS             5552..6043
                     /locus_tag="IVZ69_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HAP8184509.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6031..6585
                     /gene="srlA"
                     /locus_tag="IVZ69_002478"
     CDS             6031..6585
                     /gene="srlA"
                     /locus_tag="IVZ69_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174078.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HAP8184510.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6603..>7597
                     /locus_tag="IVZ69_002479"
     CDS             6603..>7597
                     /locus_tag="IVZ69_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HAP8184511.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2707 a         1213 c         1443 g         2234 t
ORIGIN      
        1 gttactatga ataacataat aagaaagtaa agtggattga tttgagatct ttttatactt
       61 caaaaaagat aacacccaac tttcaaaaat atgttttgga agttgggaca aacgagttaa
      121 tacattttaa tacattattt tttattcaaa aaaaatagca caatggcaaa gatcgtaaga
      181 gagatcataa gccccaatga atgactaaaa agaaaagcag aatcacatgc catatcatcc
      241 catatttctt caagaaaata aataagcggg aaaaagggaa ggaatagtag aacatcgatc
      301 cagcaccatt tttttcttct tttgaaataa cataaaacaa taaacatgaa cgtgcaggga
      361 agtaaaaaca aagctttact cataactaac aaaataccag ctccttttat ttttttctcc
      421 cccacattca aagagtaaca atggtatgta cttaataata gaaaaatgga tcaacttgta
      481 tgaataacag ctgaaaagat ctgcaccaaa taaaaaactt ccagccaaaa ctgactggaa
      541 gtttattttt ttctgaaata ttctaacaca aatatgaaaa agatggccga agctaataag
      601 ccgatttcgt agcaaaacaa tgagatacca gagtcgtaat aataaaatcc tctaatctta
      661 tggataaaat agatcatcgg acaagcagat aagagtaagt atttgttagg ccttttgaat
      721 aagtaaaaga aagcactggt cattatgata aatggtatcc aaaacaaaag tttacttaag
      781 acaatcaaat gatcaactcc catatttttt accaagagag atcataacat ctttatcgta
      841 aaaacaaaat atttttttgc tcattttgaa aatttaaaca tactcgttct tatccaaata
      901 tataaaaatc gcccctcatt catcgagagg cgataagttc taatttaact caattttttt
      961 tgtttctttt ggctgataag ctgttttagg taataccaat ttcagcacac cgtttttaaa
     1021 ggttccagtg attttttctt catcaacatt aggaagatag aatgaacgtt tgtaagagac
     1081 cgaatgtctt tctttccgta catagttgcc atcttcttta tcttctgtat gggactcatg
     1141 attggcggag atcgtcaaag tattatctga atattcaact gtcgtgtctt ctttgtcaca
     1201 gccaggcata tcagcagtta gtttgtattc tttttcattt tcgactaaat ctacttttgg
     1261 ataacttgaa acacctaaaa aatcattgaa tgctggacta aacacgtcat tgaaatcagg
     1321 gaacatgtcg cgaatgctag gtacatttgc catttttgat catcctttca ataagtattt
     1381 tttatttatc cctatttacg taataactct attttgaaaa aaatgcaagt ataatggtta
     1441 gctttgtgaa tatttcatct aatacgatac aaaggctatc tttctaattt gaaaaaggga
     1501 tcattaaaat aataagaaga aaatatgtca aaaggtaaaa aagtaaattc ttctatccaa
     1561 atatagaaaa attgaatcta gaaaaccgcc cgacaataaa tttcattaac tcagttgacc
     1621 gaaaatgaag tagataccaa aaatttatca agagagcaag tagagaagtg agtatattca
     1681 taagagaaat agctgtaacg aattattagg ttaatgcaaa tgcttattta tactccgtat
     1741 aactttctca gaaaaaatga taccaataat gacttgctag tactgtaaat ccgtataata
     1801 tcatctaatc aaaatggtgt tccatttgca tctgtcatcg taatcgatcc ttcgggtgac
     1861 actcgataaa aaccaacgct tccagatcct ccttgggaac ggatttgttt gctggaagct
     1921 gtgaacaaat aatctcgatc aattttttga taaaagctaa taacaatatc gtcactttgt
     1981 aattcggaac ggtgggcaat aagaaataga agtgctttgt cagagttttc taatggaaga
     2041 gaaggtacag tgctttcttg catttcagat gttgaagaaa tgctaaacga ctgaatactt
     2101 gattggctat gttgcgaatc tacattacca gtagaagtat tagtaatgga agtagtagaa
     2161 gtacttttag ttgaaccaac ctcagttgtt gaaatggctg ctgaagattc tttaacagaa
     2221 ttctttgttt tatatccaca ggcagaaaaa agtattacag ttcccaacaa gcctgcgtaa
     2281 atccctttat gcatgatagc tcctcctaaa atagattatc tttattcagt atatcactta
     2341 aacaaagaaa agcagatggt ttaaaatgaa aaaaccttcc caataaaggg aaggttcatg
     2401 aagataataa cttttttaat aattatagct ttctaatatc tttcatcaac ttttctagta
     2461 atcattggga aaaatttcaa gcagtagatc gcacaaatac ctacgacgat ataaatgatc
     2521 ttcgcaaaaa tagttgttga accaccagca atcatagcta ctaaatcaag ttcgaacaag
     2581 cctaccaaca gccagttcaa ccctcccaca atcaataaag ttaatgcaat agcatctaaa
     2641 gttttcatta gaattctcct ttcttaaatg ataaaacaat tatatatcaa aaagagaaac
     2701 attgcttata taacgctcag gaattttagc aatctatgca aaaagatgaa aatttttttt
     2761 gctcttccat tagtacacat tttttagctg aagctgtaaa tttcatgtct taattttttt
     2821 tagtgagctt ttatactgga tttgtaagaa aaaagaagga gaggatcaca tatgtcggat
     2881 tggttggata ttgcaggaaa agtagtaatt gtaactggag gttcctcagg aattggaaga
     2941 agtatcgtcg aaaatttgtt gaagcagaat gcacaagtag cgaattttga tgtaactgaa
     3001 tgccgtatac agcatgaaaa cctactatct ttaaaagtcg atgtgtcttc taaaacggac
     3061 atagaagaag ggatatataa agtaatgaaa catttcaaga cgatcgatgg tctagtcaat
     3121 aatgcaggaa taaatattcc ttctcttcta atagatagaa atcatccaaa aagcaagtat
     3181 gaattatcag aacaagtttt tgataagatg atcgctgtca atcaaaaaag tgtatatttg
     3241 atgagccaag cagttggaag aatcttggtg caaaagggat caggagtgat cgtgaatctt
     3301 tcttctgaat caggattgga aggatcagaa ggacagagct gttatgctgc tacaaaagca
     3361 gcgatgaaca gttttactcg ttcttgggca aaagagttag gaaagaggaa tgttcgtgtg
     3421 gtaggtgttg caccagggat actggaagaa accggtttga gaacacaaga atatgaagaa
     3481 gctctttctt atacgagagg tataagcgtc gaacagctga gaaacggtta cagtcgaaca
     3541 agtacgatcc ctctaggaag gagtggtaag ctgcaagaag tggcggatct agtctgctat
     3601 tatctttcag aaagatcaag ttatatcact ggagtcacga ctaatatttc aggaggtaaa
     3661 acaagaggat aaaggatagg ggggacgcac gtgacgctag taaacagatg gtaccaatta
     3721 ttgaaattac tagtcactca caagaaagtt tcaatccagg aagtgcaaaa agaaatcaaa
     3781 accagtaatc aaaccataaa aaaagatatt ggggagttga atgaagaaat tgccggtatt
     3841 gcaaaaatca tccaaaaaaa caaacatttt gaacttgaaa tttatgattt tgattttttt
     3901 gatgagatca tgcaaggaaa attgaaaaca gccagtgatt tcaattcggc atccaaaaga
     3961 atcgcttatt tactaaatag gctgatcgaa acagaggatt tcttacgtat ggatgatttg
     4021 tctgaagaag tcggtgtcag cagaggaaca gtggtcaagg atctaaagac attaaaagag
     4081 atgatcaatg attttgatgt aaagattaca ggcacaccaa ataaaggact aagaataata
     4141 ggagatgagc tagaattacg actactttta ttttattttg tttctcccta cttttcagag
     4201 acgaaaacag aacagtttct agaagaaaaa caagcaatca aacattttca gaagaagacg
     4261 aatgctagta aacaagaaat caccctttta acgaaagtta tcggtatttc tttgaataga
     4321 atctctagta actatctgtt gaagaagccc atcaatcgtt acagtgggtg ttttgaatat
     4381 atccaagaat tcaatgaact gatcaatcag ttggaagaaa tctatgaact aactttgagc
     4441 caatatgaaa aagattttat cagttttcct ttgaacatca tcaacacaag tataacgatg
     4501 ataaggaaag ctaactctga tttgcgctta tatttcgacc ccatgatgat gcgtattcga
     4561 cgattagatc tcattgatct ggatgagtcc ttcttatatc aagagatgaa acagcacctc
     4621 tctttattga taaatcgggt aatttttcgt tatcgattga ctgatttatt ttatggtgag
     4681 atagaaaaaa agtatccttt ttcttaccaa atcgctagcg aatgcataca agcattagaa
     4741 gctatcttgc aacataagat ctctaaagta gagatcagct acctaacgtt gtatttggag
     4801 ttagcatttc gatatcaaaa agagcatttt tcctctaaaa aagtagccat tgttcatacg
     4861 acaggaaaag gaacagcatt aatgatccaa agacaaatca aaaggatatt ggggagggat
     4921 atacaaataa cacatgtttc agaagaacaa tatgaaaaag tagatctaaa caaatatttc
     4981 gctgttttta caacgattcc gttaaaaaat gtaaatgaag agacaccggt gatccatttg
     5041 actaatcttt ttgatgactc ttggttaagg gcacaatggc aaaaagcaaa aaaaaagcga
     5101 ttagccgggt ttcattctac tgtttttttc tatcaaatat ggaaagaaaa aaagacgtat
     5161 caagaatatt taaacaaatt agtcgctcct ttgatcagag gctattatgt ggatgaagaa
     5221 tttgaaaaaa ggatcttgaa aagagaatat cagcaaagca catttgttaa caaagaattt
     5281 gcttttcctc acacaaccaa ccagctatct caacacattg ttttatcagt agggctaata
     5341 actgatcaag gtttagcaga aacaggagga aatggagtta tttttttatt tgccatacct
     5401 gaagaaatga cggctgaagt tgagaatgaa ttatttgagc tatacgatat cctatttgaa
     5461 ctcataaaaa tgggaataga tgagtttatt gaattagcac cgacacaaga atcattttta
     5521 aaactaatca aaagtaaagg agagagactt catgaatgat atgtatctat tcatagtttt
     5581 cgcagcttca gcttatgtgc tgcaagcagt tatcagttgg aagcaactaa agcatttcaa
     5641 tcaaacatat agcgaactgc gaagaaaagg aaaagtagcg attggtaaac gacctgggaa
     5701 aatccgttca ggcacgattg ttatgctagc tatagacgat catgatcaag ttttagaagt
     5761 cagaaaaatg caaggggtta catctttggc aaaatttcat tcattacctg tctatgcggg
     5821 tgaagatatc cattacatcg atcgttacca tccctcagtt cgagcggaag atcgtttgac
     5881 acaagcagct ttagaaaatg ccagagaagt atacttacga atagaggcag gaaatgaaaa
     5941 aagtgaacaa ccttcattgc cttttattgc tatgctcaat aattttcgga tatggaaaag
     6001 tacgatcaaa gaaaaaagga gtgacaaacg atggatatca taacaaaatt tgctgaggga
     6061 tttatgaggc tgttccaaac aggtgcagaa acattcataa gctggatgac aggaatcgta
     6121 ccagttgtct tgatgctgat ggttgcaatg aatacgctga ttgctttttt aggtgaagac
     6181 cgagtaacga aagtagccaa attatcagcg aaaaatccgc ttactcgtta ccttgtgtta
     6241 ccgttcttat ctgcttttat gttgggaaat cctatgtcat ttacaatggc tcgtttcctt
     6301 ccagaatact acaaaccaag ctattatgct gctcaagctc aattttgtca tacgagcaat
     6361 ggtgtattcc cccatattaa tcctggagaa ttgtttgtat ggatggggat tgctcaaggg
     6421 atcgaaacct tagggctaaa ttcgatggag ctggctatcc gatacttgct tgtgggactg
     6481 ctgatgaact ttattggtgg ttggataact gattttacta ctggatttgt atgcagacag
     6541 caaggaatcg ttcttagcaa aaaagtagag ctttcagttg attagagaaa ggagagtttt
     6601 aaatgtatgg tgatattaag atcgtaagag gaaacggcgg gtatggaggt cctttgatta
     6661 ttaggccgac aaaagataaa cacaagttca tctatgtcac aggtggaggt gagaggccaa
     6721 tgatcgtaga taaaatagaa gaactgacag gtatggagtc tatcaatggg ttcaaaacat
     6781 caatacctga tagtgaaatc gcgcttgcaa tcgttgactg tggagggact cttagatgtg
     6841 gaatttatcc taaaaaaggg ataccaacca tcaatatcgt ttccacagga aaaagtggcc
     6901 cattagcaca atatatcact gaagatattt atgtttcagc agtagggtta gaacaaatac
     6961 agccactaat ggaaactgat gataacaaag aaacagtaaa tactgcatct ccagataaaa
     7021 agtacaaata tgatacttct aaaaagataa ccgagcaaaa agcagagcag caaaactgga
     7081 tagcaaaaat tggaatgggc gcgggaaaag tagttgctac attcaatcaa tcagcaagag
     7141 aagcagtaga tacgatgatc cggacagtga tcccttttat ggctttcgtt tcccttttga
     7201 ttggtgtgat acaaggttct gggatcggta atgtatttgc taacattatg gcacctttag
     7261 caggaaatgc agttggatta acaatcattg gctttatttg ttcactgcca tttttatctc
     7321 ctttgcttgg tccaggggca gttattagcc aagtgattgg aacattgatc ggtgtagaga
     7381 ttgggaaagg aaatattcct ccccaattag cattaccggc actatttgct atcaatactc
     7441 aaaatgcatg tgattttatt ccagtcggtc taggtttgga agaagcaaaa gctgagacag
     7501 tagaagtagg tgtaccatca gttctttatt caagatttct taacggcatc ccacgagtta
     7561 tcattgcttg ggtagcaagt tttggattat atagctg
//
LOCUS       DACDAF010000112         7046 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.118, whole genome shotgun sequence.
ACCESSION   DACDAF010000112 DACDAF010000000
VERSION     DACDAF010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7046
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.118"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            1..356
                     /locus_tag="IVZ69_002480"
                     /pseudo
     CDS             1..356
                     /locus_tag="IVZ69_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
     gene            602..1198
                     /locus_tag="IVZ69_002481"
     CDS             602..1198
                     /locus_tag="IVZ69_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8184512.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPERTLCDIWNPWYTVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            1211..2110
                     /locus_tag="IVZ69_002482"
     CDS             1211..2110
                     /locus_tag="IVZ69_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HAP8184513.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNEIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            2113..2244
                     /gene="ssb"
                     /locus_tag="IVZ69_002483"
     CDS             2113..2244
                     /gene="ssb"
                     /locus_tag="IVZ69_002483"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP8184514.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            2266..2598
                     /gene="ssb"
                     /locus_tag="IVZ69_002484"
     CDS             2266..2598
                     /gene="ssb"
                     /locus_tag="IVZ69_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HAP8184515.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            2620..2877
                     /locus_tag="IVZ69_002485"
     CDS             2620..2877
                     /locus_tag="IVZ69_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184516.1"
                     /translation="MAKKISLTMDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVF
                     VYLVCSYLLKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(3036..3158)
                     /locus_tag="IVZ69_002486"
     CDS             complement(3036..3158)
                     /locus_tag="IVZ69_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HAP8184517.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            3348..3572
                     /locus_tag="IVZ69_002487"
     CDS             3348..3572
                     /locus_tag="IVZ69_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184518.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRNQLVIESMQIRNPDHFTRLMGI"
     gene            4020..4226
                     /locus_tag="IVZ69_002488"
     CDS             4020..4226
                     /locus_tag="IVZ69_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HAP8184519.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPYTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            4226..4477
                     /locus_tag="IVZ69_002489"
     CDS             4226..4477
                     /locus_tag="IVZ69_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184520.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENMETYENEYWLTKLEN"
     gene            4493..4930
                     /locus_tag="IVZ69_002490"
     CDS             4493..4930
                     /locus_tag="IVZ69_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184521.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNGQWFFQALLCLEAGVKPNTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYLENVNKYGACYIMKKEDNENE"
     gene            4923..5618
                     /locus_tag="IVZ69_002491"
     CDS             4923..5618
                     /locus_tag="IVZ69_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184522.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKRRPDTLKKGAELLRLETEKYIMNVYLERS
                     ELVENFVSYTICRKHYYSESEYYSIFESMELMEELNSKDATVDDYYLVFTKFLTCGTE
                     SIVLMGMDYELAVPEVFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNELDRK
                     RMPYQRFERKKGQ"
     gene            5999..6178
                     /locus_tag="IVZ69_002492"
                     /pseudo
     CDS             5999..6178
                     /locus_tag="IVZ69_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6240..6424
                     /locus_tag="IVZ69_002493"
                     /pseudo
     CDS             6240..6424
                     /locus_tag="IVZ69_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003027804.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, HicA family"
     gene            6458..6889
                     /locus_tag="IVZ69_002494"
     CDS             6458..6889
                     /locus_tag="IVZ69_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HicB family protein"
                     /protein_id="HAP8184523.1"
                     /translation="MLSEPLAKTYPAIFSPEEGGGYFIEFPDVQGAYTGINEDDISYG
                     IAMAQEVLGMVLADYIEHEDLLPEPTPINKISVEDDSFTTLIRVDVAKYLKDTELVKK
                     TLTIPQWADKLGKRAGINFSVLLTESIADKADNILRSGRNN"
BASE COUNT         2523 a         1182 c         1435 g         1906 t
ORIGIN      
        1 aggaacacaa accacttttc tagccaatat ccaaaaattt gtctctcact tattggaagt
       61 cgtaccaggg caaatccaat ccactgattt tggatcgacg ttacaagaag tgaaagcagc
      121 cagtgaaaag caagaagccg cgcgtcattt aggaatttgt ccaaaatgcc aggaacaaga
      181 agtcttactc tatcaaaagg tggcagcttg tacgtctgaa gcctgtgatt ttaaaaggtc
      241 agaagggttc atttgaagca acgattgttt taaaagaaga cttcactaca ggctttgaat
      301 tttctgaaaa gaaaaaaacg aacttcaaga aaagaacacg ccgcactgca aaataatgga
      361 gggttaatct tatgcgtaat accacacaca aacaacaaga aatcgaaaat caaaaagcca
      421 aaattcgttc agaacaggaa aaaatgcgtg ccagcaaacg aagactgcag caattgaaga
      481 accagcagag gattcaaaaa gaaatcgaat tagatcgata aaatcttcct aactattgta
      541 tacgtataaa cttatgttat actgttttta taagtttata cgtatacaaa ggagggagaa
      601 aatgacaaaa gcaatggtat acaagctgct agaagaattt aatggaactt tggctttgaa
      661 ggatgccaaa aaagcgggca tttctcctgt aacgatcaaa cgtatggtag atcgagggga
      721 gctggatcga gagtatccag gttttttcac cttacctggt caatttcctg atgaattgtt
      781 tatggcgcaa aaaaaatatg aacgcggcat tatttcacat attaccgcgt tagatttgta
      841 tgatttaaca gatatgatcc ctagacagat cgatctgact gtaccttacg gttatcacgt
      901 ttctgaaaaa ggattgaagg aattcgcagt tgagctacac tatacaaaag cggaatggta
      961 tgaattaggt aagattgaaa taaaaagtcg ctatgggaat cctattatag cttatgatcc
     1021 agaaagaact ttatgtgaca tttggaatcc ctggtatacc gttgaggatg aaatcaaagt
     1081 aaaagcaatc aaaaactata tggagtcgga cagaaaaaat cttagaaaat tgaatgagta
     1141 tcgacgaatt ttaccaacag acaaaacgat gcgttcttat attatggctt taaattaaag
     1201 gagaagatac atgacaccta cgcagttaaa agcaaaagtg aagaatattt ctagagaaaa
     1261 agaagttgat ccgcagcttg ttttaagaca ttttatgatg gaaaaattct tggaaaaaat
     1321 ctcagagtct ccttatcgtg aaaattttgt gttaaaaggc ggcttcttga ttggctcaaa
     1381 gtatggcatt gaaaatcgca caaccaaaga tattgatacg actttacggg aaatgaaagt
     1441 aaccaaagaa acattaacaa cggttctaaa cgaaattttt tcaacgccga cgaaagaagg
     1501 cattcaattt gagattcaag gaatgaaaga aacgagagaa gccgattact atccaggatt
     1561 tagcttacgt gtgctggcac atttggaaaa catgcggcca gattttaagg tagatgtgac
     1621 tacaggtgac tcgatctatc ctgcaacgat cactcacagt cataaattga tgtttgagga
     1681 tcgaacgatt cctttggaat cctatcctac agaacaaatt attgctgaaa aattaagtgc
     1741 aacctttgat tttttaacag ataattcgag aggaaaagat ttttatgatc tctatactat
     1801 tcctaaaatg gagaagatcg atgagaagac cttgaaagat agtgtgagaa atacatttac
     1861 acgtcgagga aaaactgatc cgttaaagat atactatgaa aaggatatgg atgtactgaa
     1921 aaatagtcac gagctaaaag atacctggaa gaaatatcaa aaaagcaatc cttatgctgc
     1981 gtcgatcacg tacgatgaga caatggattc gattagtaat ttgatggaaa aagtgattca
     2041 cgtcgaagaa aaagagcgaa aactagctta tcaaagacac caacagatga atagagaaat
     2101 ggagagataa agatgattaa taatgtgaca ttagtaggac gcttaaccaa agatcctgat
     2161 ttacgttata ccgcaagtgg tactgcagta gcgactttta ccctagccgt caaccgaaat
     2221 ttcacgaatc aaaacggcaa ttgagaagcc gattttatta actgcgtgat ttggcgcaaa
     2281 ccagcagaaa caatggcgac attagctaaa aaaggtagct tgattggtgt agttgggcgg
     2341 attcaaacgc ggacttacga caaccagcaa ggacaacgtg tatatgtgac tgaagttgta
     2401 gcagataact ttcaactatt agaaagtaaa gcagcgacag agagccgtgc gcacgctgat
     2461 caatcgtcca ccagtccaag caccgccacc tttgaacaac ggaatacagc gacgcctaac
     2521 aacaatggat tgaacgcttc acagaatcca tttggtggac aatcaatcga tattagcgat
     2581 gatgatctac cgttttagtt tgagaaagaa ggagtaagca tggcaaaaaa aattagtctg
     2641 acgatggatc tattgatacc cgtaattgca tttatagacg ggatttcttt gggcgtcact
     2701 gaaaatcctt tggtaaatag aattgcgaaa ggatcactat ttcttgtatt cgtgtatctt
     2761 gtctgttctt atcttttaaa aagagcagga aaggataatt ccttttggcg attgactaaa
     2821 gtcacagtag cagcgacagc tgttatactt acggctattc taccgcttta tatgtagagt
     2881 taacgggaaa tcgttgaact tcttgcgaaa tattgctata atgaacatga aaaagaggag
     2941 ttgcgctaac aacccctcat taacagcacc gattaaagaa cggtggcaga atattagtta
     3001 tttggaaata accgctgacc tgctaaagta gacggttatt tctttttgtc atttttaagc
     3061 atatttacaa tcaaactaat caaagcaatg gtaaacatac caaaaccaag aatggtttga
     3121 attgtctcat atgcggacaa aaggcttact cctttcatag attttagcac ttacattcat
     3181 aagcaccacc acctttccag aagtcgccac cgtcttcaaa ctttactgtc ttgactatta
     3241 tagcatatct aaaatcgaat aaaaattctc aattttagct gtttttgcta taattttagc
     3301 gaggtgatcg tgatggaaca atatattggt ttactcgata aattagggtg atcaagacac
     3361 agccattgct tgtgcgattt acattacgca cgagtcatga accaatcaat tgtgtagtgg
     3421 ccaatataga aatagcggat aaattgctga ttttggaaga aggcaagtat actatttcag
     3481 tgacaggtca cttcaataaa cgaaatcaac tagtcattga atcaatgcaa attagaaacc
     3541 ctgatcattt tacgagatta atgggcatat aaataaaaga agagctgcag tcctaaatga
     3601 ggattgcagc tctttttgtt ttacatagaa acaagaaaaa tgaaaaggcc tttttaggaa
     3661 ggcgcaagcg ccttctcaat tgaaaaacct ctctctcact ccaaccgcca ccgccgttcg
     3721 agaagaaagg aagtgaacgt tgcacgttca ctaagataag gggtcttgca aagcaagaca
     3781 aaatagaaaa aacttcctct caccaaaagg ttcgttcctg ttcgctatct ctttattgat
     3841 ttgccagacc ggcaacaagt tgccttttat caccaaaaag cgacaaggac aagggtaaat
     3901 ggcacgctgc acgcccttgt ccttgtcgct tttagttgat tcattctggc caacaaatca
     3961 ataaagaaag aactaacgaa aggaagtaaa acctttccta agaggaggca gaatcaatca
     4021 tgcgaaagaa atttgattat tggggtgttc ccttcagcga attattccca aactatcatg
     4081 caccatatac tgtcgaatgc gattgtggag aaagagcgaa atgtatcaaa agctattgtt
     4141 tgtatcaatg tccaacatgc gggaaaaaat ataccttgtc ttatggcgat tatattttga
     4201 ttgatgagaa aggaaagaaa cgctgatgaa aacacaacac aaattattga ctgtaaaaga
     4261 agtcgttcaa attttggtgg acaaagaagt catttctgaa aaagtagcag aagctttact
     4321 tattccgcgg tactggacga tagaaacccc tttagtagag gatgcaccga ctatgctatt
     4381 tgaagaccta gtgaagattg caggatatga actgcattat caagaaaaca tggaaactta
     4441 tgaaaacgaa tattggttaa ccaaattaga gaactaaaaa ggagaaaaaa atatggctca
     4501 aaattactat gacgaatttg tcaaattacc tttggataaa atggcacaaa aaatggagga
     4561 tatgacattc ctatacaatg agacacgtgt tccaaaaaaa cattataagg aaagattgtc
     4621 ggtagctgtg gaagaaatga ttgaatcggg tgtcgaaatg aatctcattg cgacctacta
     4681 tcgaacgctt gaagaactga aaaagcaaaa tggacaatgg tttttccaag ccttactatg
     4741 cttggaagca ggcgtcaagc caaacactat caaaccttct gaataccaag ctttagaact
     4801 aacgtatggg aaatttgtcg aaacgaaaaa agccaagact gtttcaagtg aatggttgga
     4861 ctacttagaa aatgtcaaca agtatggcgc atgttacatc atgaaaaagg aggacaacga
     4921 aaatgaataa ggtgatttat caactaacaa cggaagatgt gtcacacttt ttaacaaaca
     4981 aagaacattt gaatgaagta atcagacgga ttcaaaaaga ctttagttgt atggaagaaa
     5041 tgaagtactt tattcaaaga gtcgaagaac aattgtattt ggaaagtgaa acgagtcaaa
     5101 cgaaggttac agtcagcaat aattatttag acgtgtataa acgtcgtcct gacacattaa
     5161 aaaaaggagc ggagcttcta cgactagaaa cagaaaaata tatcatgaat gtttacctag
     5221 aaaggagtga actggtcgaa aactttgtca gctacacgat ttgcaggaaa cactattact
     5281 cagaatcaga atattattca atttttgaga gcatggaatt aatggaagag ctaaacagca
     5341 aagatgcgac ggtagacgat tattaccttg tatttactaa atttttgacg tgtgggacgg
     5401 aatctatcgt gttaatggga atggattatg aactcgctgt acccgaagta tttttgaggg
     5461 aatatgtaga agaagtagat aacccaggcg acgactggta cacgacttta actgattttt
     5521 tagataccta cacttacgac gatacagaag aaatccaaaa tgaacttgac cgtaaacgaa
     5581 tgccatatca acgatttgaa aggaaaaaag gtcaataacc atttataccg aaaagtgaga
     5641 atgtgtgaaa taaaaacaaa aaaccttgaa attaagggaa tggttcttat ttcgcaccaa
     5701 tcgctccaac cgcccccgcc gcttaggtgg tgcgaaataa gcgagcaaag cccgaaaacc
     5761 taagagaaag aaggagattt atatgaacaa aattattccc ttattattag tcctatttgt
     5821 tggagaaata cttatgcgac ttagtgcagc tgtacattta aacctcgcag tatttttggt
     5881 aatactaatg ttttgtttga tcttttggcg atttgtatta gccctcgtaa gtctactatt
     5941 caagatgatt gcagccatat ttttcatagg attatttcga tgaaaggaga gagtaccaat
     6001 gccaattgca ataggaaata aacggttacc cgtgacgttg gatgaaaaga gacaaaaaga
     6061 attgcagtaa ccaaagcaga agtacggcaa aagtgaatcc aggattatgt gtattgcgtt
     6121 agatttattg attgcgcaag aaaaagcagg atttgacata ccagcactca aaaagtgatc
     6181 gcactttgcg cacgtgttaa tacgtgttat aattattttg taaggaggta tagtgcacaa
     6241 tgccacttac gggaaaagaa atgcttaagt tattgaaaaa aatggctggg ttgagcgaag
     6301 gcaagaggga tttcatcatc atctttataa ggatggtgtt agaatcactg ttcctgttca
     6361 tgccaatcaa gatcttggcc gaggacttga gcgaaaaatt ttaaaggatg cgggattgaa
     6421 ataatctcgc attcgattaa agaaaggatt gactgaaatg ttaagtgagc ctttagcaaa
     6481 aacctatcct gctattttta gcccagaaga aggtggtggg tactttattg aatttcctga
     6541 tgttcaaggt gcttacacag gaattaacga agacgatata tcttatggaa ttgctatggc
     6601 acaagaggtg ttaggtatgg ttttagcaga ttatattgag catgaagatc tacttccaga
     6661 accaacacca atcaataaga tttctgttga agatgattct tttactactt taattcgtgt
     6721 agatgttgcc aaatatttga aagacacaga acttgtcaaa aaaaccttaa caattcctca
     6781 atgggcggat aagctaggca aaagggctgg cataaatttt tcagtccttc taacagaatc
     6841 aattgcagat aaagcagata acattcttcg ttctggaaga aataattaga actcaaaagg
     6901 gtcagaaact taaaaatctt tggcttcttt ttttactaca aagatggctt ctttaaatta
     6961 tttgcctgat tgatttaaaa aaattgcgca aagactacga gctaattaag ttgctcgtgg
     7021 tcttttttta tgaaaacttt ttagat
//
LOCUS       DACDAF010000113         6807 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.119, whole genome shotgun sequence.
ACCESSION   DACDAF010000113 DACDAF010000000
VERSION     DACDAF010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.119"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..770)
                     /locus_tag="IVZ69_002495"
     CDS             complement(<1..770)
                     /locus_tag="IVZ69_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
                     /protein_id="HAP8184524.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHFFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKVRTLNDKYVAI
                     FMDATYIPLKRQTVSKEAIYIAIGIREDGTKEVLSYAIAPTESTYVWNELLQDIYSRG
                     VHDVLLFITDGLKGMKDTIHQIYPKAKYQHCCVHVSRN"
     gene            864..1607
                     /locus_tag="IVZ69_002496"
                     /pseudo
     CDS             864..1607
                     /locus_tag="IVZ69_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
     gene            1619..2050
                     /locus_tag="IVZ69_002497"
     CDS             1619..2050
                     /locus_tag="IVZ69_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIA"
                     /protein_id="HAP8184525.1"
                     /translation="MLKEQLSGNTMFMDAIDSWQEAIRVSARPLIGKGIIEESYVQAM
                     IQNVLDNGNYIILLPLVAMPHARPEFGSKGVGMSFLCLDKPVMFPSEEPVKFFFTFSS
                     DSPKGHLDLMANLGELLSDEKMYQKLFDVKTEKALLDLIKK"
     gene            2064..3509
                     /locus_tag="IVZ69_002498"
     CDS             2064..3509
                     /locus_tag="IVZ69_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HAP8184526.1"
                     /translation="MEVANKKKRVSMRAKVQAIGGFLTNMVLPNIGAFIAWGIVTALF
                     IPTGWFPNESLNELVSPTVSYLLPLLLAYTGGRMVGGTRGAVLGTIGTIGLIIGADIP
                     MFMGAMIMGPLGGWMMKKTDDFLDGKVPAGFEMVVNNFSIGIIGFILMCLSYLVVGPI
                     IQSANQFVTSAIEALVSTGFLPILSLINEPAKVLFLNNVIDQGVYYPLGMQQTLEAGR
                     SIYFMVASNPGPGLGLLLAYSLFGKKAAKQTAPGAIIIHFFGGIHEIYFPYVLMKPLT
                     ILSMIAGGMTGIITFELFDAGLVAGPSPGSIFSYLALTPRGNFLGVMAGVVTATLVSF
                     FVTSVILKADKSTDEDRNFELSVQKSKTMKSEGRKLLKEENAREICTEKKEMNKISFA
                     CDAGMGSSAMGATIFKKKLQKAGITDVEIKNYRIEEVPEDSDLVIVHQDLEERTRKAH
                     PNMKIVTLKNYLQDPVINGLAEEIIGLKTED"
     gene            3795..5420
                     /locus_tag="IVZ69_002499"
     CDS             3795..5420
                     /locus_tag="IVZ69_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP8184527.1"
                     /translation="MKKIYSKEIDCFRGLAVLAVIFYHLPNSLLPGGLQGVTIFFVVS
                     GFLMAKNTIRDEKNRQFSFLHFYYKRIKRIYPFLLFSLVVFIFILGISNIRLIGNIRS
                     ELPSLIFGYNNWWQLNQGVSYFDSYFNASLFKHYWSLSVELQFYLIWPFLFIVIKRMR
                     RKQVFYLIYTLIFVSILFSLFLPSTKAYYHTIAKLFPFLLGVWGYFNRITIGRFFEQN
                     TFSKIWLLLLASLCLILFPIFPYTLNELLISICFALLLASVDDMNIAKKTKIASTKLS
                     FVGKISYELYLVHFPVLIALTNLFKHHHWKYLDIAGLFTVFLCTLLMITCFRKGVQKM
                     RSPKIWTAMALMIIGVSVLVLRAPASRLTADQNQLQSLLKENSSKANAGENLLSQEKK
                     ILFIGDSVMLGAYQELKETFKKEALVDAKESRQITALPEILKEHKDLVSYQQIVIGLG
                     TNGVITDEAIEQTMSLLKDKKVYWVNIKAPTGWQDTINATLATLPNQYSNITMIDWYS
                     ESKNHPEFFYDDETHLNESGRTAYAKYIASVIQ"
     gene            6052..6405
                     /locus_tag="IVZ69_002500"
     CDS             6052..6405
                     /locus_tag="IVZ69_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184528.1"
                     /translation="MNSFKKKFVSRFLNMKNFFEKKGDYDAYNYVLNLEKQTYYTLRK
                     NDDNDFWTMLPKMLSIDSKLSLLEEFINLDIEEFCGGKELINMVESDYHTYYKESCGY
                     KVDEQCPQSIIFYIE"
BASE COUNT         2302 a          994 c         1338 g         2173 t
ORIGIN      
        1 atattacggg aaacgtgaac acagcaatgt tggtatttag ctttaggata aatctggtga
       61 atcgtatctt tcatgccttt taagccatcg gtaataaaca gtaagacatc atgaacccct
      121 ctggagtaaa tgtcctgtaa caactcattc caaacgtagg tcgattcagt cggagcaatc
      181 gcataactta gtacttcttt agtgccgtct tctcgtatac caatggcaat atagattgct
      241 tctttggaga cggtttgccg ttttaatgga atataagtag catccatgaa aatagcgaca
      301 tacttatcat ttagagttct aactttaaat gcatttactt cttcagtcag cactttagtc
      361 atgttggaca tggtttgggg cgtgtagtga tgcccataca ttttctcaat caagtctgcg
      421 atttccgaca tggtaatacc ttttcggaag aagtgaatga cggtctcctc taaggtatca
      481 ttcgtccgtc tataagcagg aacagtctgt tgcttgaact cgccgttgcg gtcgcgcgga
      541 atctggagat gaagttcccc gtactcggtc ttgaccgtac ggtcatagga gccgttacga
      601 gaattacccg tgttaaaacc aatgcgatcg tacttttcgt aatcgaggaa agccgttaac
      661 tccgttttga gaagcgtatt gacagctttt tccaaatgga cacggaataa ttcattcaaa
      721 tcgcctttgt tcgctagagt ctttagaatt tctgtagtaa aatcgttcat atggaagtcc
      781 tcttttctgt gaatgtgttg tggtaactct attctacaga agggacttcc ttttttctat
      841 ttacacaaaa tattttacac tctcaaattt attctttgct gtcagaaaaa gaacaagaga
      901 attttgatga atatgcatat tttgtgaata cggcaatcga tcgacaatct ttaggaaaag
      961 ttcttggagg aaaaatgatc tctgttgtcg aaccttatta tgaatggata atggatcgac
     1021 agcagttaga tccaactaca tcttttgata tgaaaaatgt aaatttggtt gatgatatgg
     1081 agccttacat tgagcgaaag ctttatatcg ttaatgctgc tcatgcggca gtagcttatt
     1141 taggcgcact gaaaggatat aagacgattc aagaagcaat ccaaaatatg gagattttca
     1201 atctagtcaa gcaattttta atggagaata tagagtactt tgtacaaaaa tatcattttt
     1261 ctagagaaga attaacatct tttgtggaaa aaacattaaa ccgtcatggg aatcagaaac
     1321 tctccgatga aattactcgt gtaggaagtt cccctattcg aaaattaggc cctaatgatc
     1381 gtttaattgc tcccatagta aaactagatt catatcattt accttacgat gcaggaataa
     1441 aagtaattgc tgcgggatat cattatcgga atcttgctga tccagaagct gaacaactac
     1501 gtcgaatgat tgtaaatgat gggttgaaag caacgattaa aaagatttct cgtttggaag
     1561 gtaagctgct gaatgaagtt gtcgctgctt atgagtccca gatttagagg aggagaatat
     1621 gctaaaagaa caattgtcag gaaatacaat gtttatggat gcgatcgatt catggcaaga
     1681 ggcaatccga gtaagtgcgc gtcctttgat aggaaaggga ataatagagg aaagctatgt
     1741 acaagcgatg atacaaaatg tgttggataa cggaaattat attatattac tgccactagt
     1801 agcaatgcct catgcgcgtc cagaatttgg gagcaaaggg gtcgggatga gctttttatg
     1861 tttagataag ccagtcatgt tcccaagtga agaaccagta aaattcttct ttaccttttc
     1921 ttctgattcg ccaaagggac atttagactt aatggccaat cttggagaat tgctgagtga
     1981 tgaaaaaatg tatcaaaaat tattcgatgt gaagacagaa aaagcattgt tagatttgat
     2041 aaagaagtaa aggagagaag aaaatggagg tagcaaacaa aaaaaaacga gtctccatgc
     2101 gagctaaagt tcaagcgatt ggcggtttct taacaaatat ggtattgcca aatataggcg
     2161 catttattgc atggggaatt gttactgcat tattcattcc aactgggtgg ttcccaaatg
     2221 aatctctgaa tgaactcgta agtccgacag tcagctatct attgccgtta ctacttgcct
     2281 atactggtgg tcggatggtt ggtggtacac gtggagctgt tttaggtaca atcggaacaa
     2341 taggtttgat tattggtgct gacataccaa tgttcatggg agcaatgatt atggggccac
     2401 ttggtgggtg gatgatgaaa aaaacagatg attttttaga tgggaaagtt cctgctggtt
     2461 ttgaaatggt cgtcaataat ttttctatag gaattattgg tttcatactg atgtgccttt
     2521 cttatctggt agttggacca ataatccaat cagctaatca atttgtaacg agtgcaattg
     2581 aagcattagt ttcaactggt tttttaccga tactgtcctt aatcaacgaa ccggcaaaag
     2641 tcttattttt aaataatgtt attgaccaag gtgtttatta tccattaggt atgcaacaaa
     2701 cattagaggc aggcagatca atttatttca tggtagcatc aaatcctggc cctggcttag
     2761 gactattgtt agcttattct ttatttggta aaaaggcagc aaaacagaca gcaccaggtg
     2821 caatcatcat ccattttttc ggcggaatac atgagattta ttttccatat gtattaatga
     2881 aaccactcac tatattatct atgattgctg gtggaatgac aggaatcatc acttttgaat
     2941 tatttgatgc gggcctggta gcaggtccaa gtccaggttc tattttttct tatttagctc
     3001 taacgcctcg gggaaatttt ttgggtgtca tggcgggagt ggtcacagca acactggttt
     3061 ccttttttgt aacatcagta attttaaaag cagataaatc aacagatgaa gacagaaatt
     3121 ttgaactatc agttcaaaaa tcgaaaacga tgaaatcaga aggaagaaaa ttattaaaag
     3181 aagaaaatgc tagagaaata tgtaccgaga aaaaagagat gaataaaatt tcctttgctt
     3241 gtgatgcagg aatgggaagc agcgcaatgg gcgcaacaat attcaagaaa aaattgcaaa
     3301 aagcaggtat tactgatgtt gagataaaaa attatcgaat tgaagaggta ccagaagata
     3361 gtgatttggt gatcgtacat caagatttgg aggaacggac tagaaaagca catcctaaca
     3421 tgaaaattgt gacattaaag aattatttgc aagatccagt aatcaatgga ttagcagaag
     3481 aaatcattgg attaaaaaca gaagactaat ttatgggaat ttttgattaa cctttattaa
     3541 aattattttg cctaatataa aaaggttgtg acatggcttg tgtcgcaacc tttttttgtc
     3601 gcacaaataa ttaatcggat attttatgtt catatttttt gtgatcaacg agaactgatg
     3661 gggcaaagat acattttaga tacttttaac tgttaattta caaaacaagg tgaaacgaat
     3721 agaaaaatga aaaaatcgat acggaagaat atgtttgatt aaaacatgca tgaagagaag
     3781 gaggttgatg atacatgaaa aaaatatatt caaaggaaat cgattgtttt agaggccttg
     3841 ctgttttagc agtgatattt tatcatttgc caaatagttt gctgccaggc ggattgcaag
     3901 gagtaacgat cttttttgtg gtttctggtt ttttaatggc taaaaatacg ataagagatg
     3961 aaaaaaacag acaattcagt tttttacatt tttactataa gcgtatcaaa cgtatttatc
     4021 catttttact gttttctttg gtcgtattca ttttcatact agggattagc aacattcgat
     4081 tgataggaaa cattcgtagt gagctaccca gtttgatttt tggctataac aattggtggc
     4141 agctgaatca aggagtatct tattttgact cttactttaa tgcttcttta tttaaacatt
     4201 attggtcgct ttcagttgaa ctacaattct atttgatatg gccatttttg tttattgtca
     4261 ttaagcgtat gagaagaaaa caagtgtttt acttaatcta tacattgatt tttgtttcta
     4321 ttctttttag tttgttttta ccttcaacta aggcatatta tcatacgata gctaaacttt
     4381 ttccattttt attaggagtt tgggggtatt ttaatcgaat aactattggc cgtttctttg
     4441 aacaaaacac ttttagtaaa atctggcttt tattactagc tagtctttgt ctgattctgt
     4501 tcccgatttt tccttataca ctaaatgaac tactgatcag tatttgtttt gctctattgt
     4561 tagccagtgt cgatgatatg aacattgcaa aaaagaccaa aatcgctagt acaaaacttt
     4621 cttttgtagg aaaaatcagt tatgaacttt atttggtgca tttcccagta ttgattgctc
     4681 tgacaaatct attcaaacat caccattgga aatatttgga tatcgcaggt ctattcactg
     4741 tgtttttatg tacattactc atgattactt gctttagaaa aggagtgcaa aagatgagat
     4801 cacccaaaat ttggacagct atggcactaa tgataatcgg agtttctgta ctggtattac
     4861 gtgctcctgc cagtcgactg accgctgacc aaaatcagtt gcaaagttta ttaaaagaaa
     4921 actctagtaa agcaaatgca ggagaaaatc tgttgtcaca agagaagaaa atattattta
     4981 tcggtgattc tgttatgctg ggggcgtatc aggaactaaa ggagacattt aaaaaagaag
     5041 cattggtaga tgcaaaagaa tcaagacaaa tcactgcgtt accagaaatc ttaaaggagc
     5101 ataaagattt agtttcttac caacaaatag tgatcgggtt aggaaccaat ggtgtgataa
     5161 cagatgaagc tatagaacaa acaatgtctt tgctgaaaga taaaaaagta tactgggtaa
     5221 atataaaagc accaactggc tggcaagata cgataaatgc cacattagct acattgccaa
     5281 atcagtattc taatataacg atgatcgatt ggtatagtga gagcaaaaat catcctgaat
     5341 ttttttatga tgatgaaacc catttgaatg aaagtggacg tacagcttat gcaaagtata
     5401 ttgcttcagt tattcaataa ggtagtgatt acgtgtgtta accttacttt ttcctaatag
     5461 gtgaatcaat ttaaataaaa aatacttcat atgataaacg gtgtttaaga ggaggagctt
     5521 tttaatattc gtggtaaaaa agagatgggc gaggtcgtta actgagagct tcttggaaag
     5581 aaatcgcttt ggatttatcc tctttgttat acagaacatg agcgagacga caatactagg
     5641 atgtatgttc tgatcgaagt tttatggtta caagcagcaa tcagcttaga taaaattaag
     5701 gatcgtagga accaagtaaa gaaggctgtt agtaaagaaa caaacgatca agtatgtttt
     5761 actcttaaga agatgcagtg aataaataat agtaatataa tgctagaagg gactgtgaca
     5821 aaagacgtgt cacagccttt tttgttattt taattatcgt ccagtctttt tttataaatg
     5881 attgcttaag cattaaatat taaaaaatat agagttcaaa attactgcac aattagatga
     5941 aaaatttgaa caacaaaaag tgtattttta tactataata gcttttgaat ttagttactc
     6001 tattcaaaag ttatgctatg gacaagaaaa agaataaata gaggtgagaa aatgaatagt
     6061 ttcaagaaaa aatttgtgag tagattttta aatatgaaaa atttttttga aaaaaaggga
     6121 gattatgatg catataatta tgtattaaat ctagaaaagc aaacatatta tacactacgt
     6181 aaaaacgatg ataatgactt ttggactatg ttacctaaaa tgctttcgat tgactctaag
     6241 ctttcccttt tagaggaatt tattaattta gacattgaag aattttgcgg gggaaaagag
     6301 ttaattaata tggtagagag tgattatcat acctattata aagaaagttg tggatacaaa
     6361 gtggatgagc aatgtccaca atcaattatt ttttacattg agtaatatga actattaagc
     6421 aggaaagcaa ctagaagcta ctgatttagt atttacaaat ataaactata ttgctaacaa
     6481 ttattttcta gaaggaataa aagaactaag aatcaagacg ttatcttgat tcttagttct
     6541 tttaacatgg aaaagatgga taatgcactg ttaattcatg atgcatcatc agaaaagttg
     6601 gaaggagaag atagaaatca ttaaatgatt tctacagatg gtaaatgaaa aaacaaaata
     6661 ttagcaaaaa tttgcctaaa tagatagtaa cactttctaa attaaataca agcgcattca
     6721 taaaatgttt atacaaatat ctatgtgata aaaattggat atgttcacaa taaataggaa
     6781 ttaaaataac gaatttacgt ttgtttt
//
LOCUS       DACDAF010000114         6749 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.120, whole genome shotgun sequence.
ACCESSION   DACDAF010000114 DACDAF010000000
VERSION     DACDAF010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.120"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..368
                     /locus_tag="IVZ69_002501"
     CDS             <1..368
                     /locus_tag="IVZ69_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HAP8184529.1"
                     /translation="ESLIEKEWLYQVWGDNIVNCLKLVGNNDYSQFYDWYKKFKYAIK
                     SAEKEQKIQLKIIYEICNNKYFVDYVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASL
                     KNKALELIELQISEGIDKQ"
     gene            649..3342
                     /locus_tag="IVZ69_002502"
     CDS             649..3342
                     /locus_tag="IVZ69_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HAP8184530.1"
                     /translation="MKIVKEKIASRKIHWLALSILVLMFIVVFTGNVVQASIFNWFDD
                     TESQTEFLNNPVYQSYLKKYNGNFYSQFGLWIGWSVIKSMFAIVDGIQNMIPEVLDLF
                     SFIESTGMNKVYQSVLSTVVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSVALI
                     LLMPTLIGSTEKLSGIMFAKTLYNDATSINNQDGGVAWSLIEQGVTDLAYINKTDQYS
                     TIDKTNDRNNLTKENFWKTDLTQVLTDNVIDKMEKENPTADNLRYELVENSDNEFVAT
                     KFSDNFLSTFVDGIKSGYYRYQANLWGISFGLIALAVAYVFSAFIIITAILELAFKRV
                     LGVLVFATDLETGQRSKQVLSDILQCYLTVGFQGFGLSMFAMFINYLNTGEGISANIF
                     IKTIAYICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGTGGMNRS
                     KGGKNNGGNDQAEGEERKPERNFGQSLSKKANKTGKALGYAHERGLSGLASDGSTMAS
                     ERATKPFKSMRDIANDTKSKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSMPT
                     RLSDRKDGAKVENADSIMSSSERMREAMKNNAESNNNPVSAIQQKVQQDIEERKNAMH
                     GQAKSAEELINQKRHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAK
                     NSNTGLEKLVKENPQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQG
                     TKTIDVRENLQSSSTSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDV
                     RENVQSSTSSQGFKTVDVRENVQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIID
                     SEIRENDKGSKPRRRFTYEDNELFRDTLNDPNPLFDSLLKK"
     gene            3356..3553
                     /locus_tag="IVZ69_002503"
     CDS             3356..3553
                     /locus_tag="IVZ69_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184531.1"
                     /translation="MQLILQISTHDFLELDELCESVKKATNEKITVTNYIELMIQEEL
                     KMKNEIESDFKCCSLEKNVRG"
     gene            3557..4168
                     /gene="mobC"
                     /locus_tag="IVZ69_002504"
     CDS             3557..4168
                     /gene="mobC"
                     /locus_tag="IVZ69_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HAP8184532.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            4153..5544
                     /locus_tag="IVZ69_002505"
     CDS             4153..5544
                     /locus_tag="IVZ69_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HAP8184533.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            5760..6074
                     /locus_tag="IVZ69_002506"
     CDS             5760..6074
                     /locus_tag="IVZ69_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184534.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGVFGSKANMFRVMVSNLP
                     VLASPSNNKFNDSESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            6067..6561
                     /locus_tag="IVZ69_002507"
     CDS             6067..6561
                     /locus_tag="IVZ69_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184535.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTIDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLKNDTEKPIRPQQW
                     SIENKDGEELYEYAMILDNPEYIESDKEETVNYYYELPIERQDYQIVVRRANGYFVGL
                     PFTL"
BASE COUNT         2556 a          907 c         1335 g         1951 t
ORIGIN      
        1 ttgaatcatt aattgaaaaa gaatggcttt atcaggtatg gggggataat attgtaaact
       61 gtctgaaatt agtgggtaat aacgattaca gtcaatttta tgactggtat aaaaaattca
      121 aatatgcgat taaatctgct gaaaaagaac aaaaaattca actgaaaatt atctatgaaa
      181 tctgtaataa caagtatttt gtagattatg ttagagaaca gctatcaatg actttacgtg
      241 acttgatacg aagagcaaaa acagatcacc gtatcaaaca aaaagacgat tatatctttg
      301 cttctctaaa aaataaagcg ttagaactaa ttgaattgca aatcagtgaa ggaatagata
      361 agcaataaga atagaattga gtcaaatgaa gtggaggggt atctccgctt catttgagaa
      421 ctttgaatat aggaggggtt attttgattg aaaatcgttt aatagatcaa gtttggtgtc
      481 tagatcaaaa tacagataat ctcgaattaa tcgagactat ttgcttcaac actatagttc
      541 tcgatttaag atctgaaaat gacaattgtg taactcatat cataattgac agaaaaacag
      601 ctcagaagct ctctgagagt ctcagaaaat gggctgaggg aggtaataat gaaaatagtt
      661 aaagaaaaga ttgccagtag aaaaatacac tggttagctt tgagcatact tgttttaatg
      721 tttatcgttg ttttcaccgg taatgttgtc caagcaagca ttttcaattg gtttgatgac
      781 acggaaagtc aaactgaatt tttgaataat cctgtctatc aatcgtattt aaaaaaatat
      841 aacggaaatt tttacagtca gtttggattg tggatagggt ggtctgttat aaaatcgatg
      901 tttgcaattg tagatggtat tcaaaatatg attcccgaag tgttagattt gtttagcttt
      961 attgaaagta cgggaatgaa taaagtttat caatcggtct taagtacagt tgttattggt
     1021 ttaatgatac tttcactgat gtttgttggt tacaaaatga ttactggaaa aggaacagtg
     1081 gatttaaaat cggttggaat gaacgtagtg atgtctgtag cattaattct tttaatgccg
     1141 actttgattg gatcaacaga aaaactttca ggaataatgt ttgcaaagac tctttataat
     1201 gacgcaacta gtatcaataa tcaagatggc ggtgtagcat ggtcattgat tgagcaggga
     1261 gtgacagatt tagcttatat taataagaca gatcaatatt cgacaattga taaaacaaat
     1321 gaccgaaata atctaacaaa agaaaatttc tggaaaacgg atcttacgca agtattgaca
     1381 gataatgtaa ttgataaaat ggaaaaagag aacccaacag ctgataatct gcgttatgaa
     1441 ttagttgaaa attctgataa tgaatttgtt gctactaaat tttcagataa ttttttatca
     1501 acctttgttg atggtatcaa atcaggatat tatcgctatc aagcgaacct gtggggaatt
     1561 tcttttggat tgattgcttt agcggtagcg tatgttttta gtgctttcat tataattaca
     1621 gcaatactcg agttagcatt taaacgtgta ctcggagttt tagtatttgc tactgactta
     1681 gaaacaggac aacgatcaaa acaagttttg tcagatattt tacagtgcta tttgacagtc
     1741 ggatttcaag ggttcggttt atctatgttt gcaatgttca taaattacct aaatactggc
     1801 gaaggtatct cagcaaatat ttttataaaa acaattgctt atatctgtgc tgtgtttgtt
     1861 ttaatcaaag gcagtggaac agtcatgaga tactttggtg tggatattgg actcaaagaa
     1921 ggctatgggc aacttgcttc tgcttttgga atgggtgcaa tgctattccg taaaggaaca
     1981 ggtggtatga accggtctaa aggtgggaaa aataatggtg gaaacgatca agctgaaggg
     2041 gaagaacgaa aacctgaacg caactttgga caatcacttt ctaaaaaagc taataaaacg
     2101 gggaaagcgc ttgggtatgc tcatgaacgt ggattatcag gtttagcttc agatggatct
     2161 acaatggcta gtgaaagagc aacaaaacca tttaagagta tgcgtgatat agctaatgat
     2221 accaagagta agtttaaaga aggtttagat gatggtactg tgtccgctat taataaaaat
     2281 agcaaaccta tgttagctaa aaataaagaa gatgaaactg gaaaatatgc tgattccatg
     2341 ccaacacgtc tttcggatag aaaagatggt gctaaggttg aaaatgccga tagtattatg
     2401 tctagttctg aacgtatgcg tgaagcaatg aaaaataatg ctgaatcgaa taataatcct
     2461 gtaagtgcaa ttcagcaaaa agtccaacaa gatattgaag aacgtaaaaa tgctatgcac
     2521 ggtcaagcta agtctgctga agaattaatt aatcagaagc gtcatgaagc gaaatacacg
     2581 cctgaagcaa tgaatcgcga ggaaataatg ttaaggaaac gtgtagaagg gcggacaggc
     2641 gctaatattg acggaaaaga agcgttgacc aaagaaagaa ttcaagaagc taaaaattca
     2701 aatacaggat tagaaaaatt agtcaaagaa aatccacaaa attctacaag tagtcatggt
     2761 ggccgatcag tagatgtccg agaaaatatt caaggttcac tgaatggtca tgttggacgg
     2821 aatgttgatg taagagagaa tttacaaagt tcttcaaatg ctcaaggtac taagacaatt
     2881 gatgttcgag aaaatctgca aagtagcagt acaagtcaac caaaaacagt agatgttcga
     2941 gaaaatgtac aaaattctac aagtagtcaa gggtttaaat cagtggatgt ccgagagaat
     3001 gtgcaaggta gcagtgcaag tcaaccaaaa acagtagatg ttcgagaaaa tgtacaaagt
     3061 tctacaagta gtcaaggatt caaaacagta gatgttcggg agaacgttca aaaagatagt
     3121 ggagaaatga aagaaaaaac acaaaaaatc aatatcgttg aagacagaaa gtcagcgaaa
     3181 aaatttgatt caaatcatga aacagtgatt attgatagtg aaatccgtga aaatgataag
     3241 ggatcaaaac caagacgaag gtttacctat gaagacaacg agttattcag agatacactt
     3301 aatgatccta atccactttt cgatagttta cttaaaaaat aaagaggtga ttgtcatgca
     3361 attaattcta cagattagta cacatgattt cttagaactt gacgaattat gtgaatcagt
     3421 aaagaaagca acaaatgaaa aaatcacggt cactaattat attgaactga tgattcaaga
     3481 agaattaaag atgaaaaatg aaatagagag cgatttcaaa tgttgctctc tagaaaaaaa
     3541 tgtgagggga taatcaatgg atgataaaca aaaaatgtac gaaaaaaatc gcaaacatag
     3601 tgaggcctta aattttcgtg tcgataaaaa gacttatctt gaactgacat tgattgcaaa
     3661 acaaagggga atttctagag cagacgtttg ccgtgagcgg ttaaagggac tcaaatatga
     3721 accgccgttg ttagctgaag atgatagggt agttttaacc aaacagttaa atcaaattgg
     3781 taacaatttg aatcaagcgg taaaggcatt aaatatcatt gctaaatatt ttagagaaga
     3841 atctgaagat aaaaaagaaa agagcctaca ttttagtttt gatgctagcc gttacaacat
     3901 ttttaaagat gaacttgcga atagcatagc aaaaaagttg atgattagtt atccagatga
     3961 catttttttg gagtccaatc ggagtgcccc ctcttttttt aaattatcag aagtagaaaa
     4021 agaatatttc gaatattgga tagaaaagca aactagaccg ggtacgaaag aagagtattc
     4081 ccaaaaagtt gatcggaatt taattcactc aattcagatt attgcaagtt taaaagatga
     4141 ggtgaaacaa ctttgggagc tactataaca tcgaaaggac gcaagaaaaa tttatcctcg
     4201 ctattacaat atgcagctaa tccttcaaaa aaagaaaaat gtgttgcagt ctcaggaata
     4261 aattgtagtg atgatagtga ggaagcactg caagaaatga atttagtacg taccaagatg
     4321 aataaatcta aagatatagc acaagcgttt catgttattc attcgtttga taagagtact
     4381 tctaaagagt taagtattga taaaatgcac gaaatagctg tcgaatttgc agagaaagct
     4441 tttccaaatt cgcaaatcat tgttgcaagt cacaatgata aagatcattt tcatagtcat
     4501 cttgtcatta ataatattaa catggaaaca tgtaaaaggt tgcgtattga ccctaaagat
     4561 ttagaactaa tgcgaaaaat taacgatcaa gtcctcaatg aacatggtct tgaatcagtg
     4621 aataatgagt actatgaaaa cttagaaaag agaaccaatc tttattcaaa cgatccttct
     4681 aagatgaaat atggaaaaat taattatcaa gagtttgtgc aaaatgcgat cgaagcaacg
     4741 ttggaaaaat gcgaagtgaa ttcttttgaa gatttttcgg atcatttggc aaaagaatat
     4801 aacattgaag tttatcaatt ttcaaaaaca aataacaaac ttggctatgt tctttacaaa
     4861 caaggtgtaa atttctatga gcgtagaggt gagttaatta ctttaggaag agataaacaa
     4921 tctagaaaag aaaaaagtca gtatgtcgaa cgtactttta gtgcaagaaa gttagggaaa
     4981 agatattcat ttgaatctgt ttctgaacaa cttgaaaaga atttagaaga atcacatata
     5041 aaaaattttt ttaatatgga aagagagcaa gttatgtcgc taattagtgg agtaaattac
     5101 aaaactggtg agttaaatgt accttttgtg gaattagatt ccatcgcaca aaagcaattt
     5161 agcgaccgtg aaggcgatga aaaattcatt aaatatgatg acttcttgcg agaggtagac
     5221 aagcattttg taaacacaat gtctttagaa gatgatcaag aatacacgat taaacttcat
     5281 acggatgtga atcctcaaac tttacgtagt gcgaaaagta aaacaatttc tattaaaaag
     5341 actgatcaga aagagttatt tctaccggca aagggttttg aaaattgttc tcatacacct
     5401 tctgctaaac agattcacta tcaaatcagt cgcataatga atgacgatgt aaaaatgtat
     5461 cgtgctaaaa aggattatga attcacacaa caaatgattg aaaatcagca aaaaaggcaa
     5521 caaaattttg aaatggaatt ctgaatgggc ttgttagtgg actttccagt tttttgccta
     5581 tgaagagttg cttggaaaga agcagttttt aggacatacg ccagctaccc atctacttgc
     5641 cagtcaatcc gccccgctca cgctaggcta ctttctggca agtcagatgg tgggtaaatc
     5701 tctgagggag caagctccct acagactccc tcccaaaaaa agaaaggtgg aagaaaaaaa
     5761 tgaactatcc atattttaaa gtctcggctt cagaagaaac taaagaaata ttcaacaatt
     5821 tttacaacca aaacaaagga gtttttggtt ccaaggcaaa tatgtttcgt gttatggttt
     5881 caaatttacc agtgttagct agtccatcaa ataataaatt taatgattct gaaagcatta
     5941 aatttgaaca aaaaatttca gaactagaat caatgataag taatgaagta attgaaaagc
     6001 ttgatgacat tgatcaaaag ttatcgtatt ctctaaaaaa caaatacaaa acggaggaga
     6061 aaaaagatgt ttaaagttta cttcccgttt cagtggctcg ttaaaggaat tcttttagtg
     6121 ctactaggat tgattctttt tggaagttat ctaacaatta aagccagaca ttttccagaa
     6181 gaaaagccaa taaaaattgt aacaatagat ttaaaaatag gtgaaactta tcaggcagat
     6241 ggggttgaac taacatttaa aaatattgaa gtgaccgaaa aaagaaatga atttgcacaa
     6301 catgatcgtg tattacaagt gacctataca cttaaaaatg atacagaaaa accaatacgt
     6361 ccacaacaat ggtcgattga aaataaggat ggtgaagagc tttatgagta tgctatgata
     6421 ttagataatc cagagtatat tgaaagtgac aaagaagaaa cagtaaatta ctattatgaa
     6481 ttaccgattg aaaggcagga ctaccaaatc gtagtacgta gagcgaatgg ttattttgtt
     6541 ggattaccct ttactttgta agtcttattt tgttagtggc ttttaagtta atatcatttt
     6601 tgtgattttt gaaaatgaaa gtgaggaaat tggaagaatg gctgaagaaa ataaagttgt
     6661 tccgtttgaa acattagtga taaataagga agagtttgag caactttttc ttgatttttt
     6721 tattcaatat gacaggattt atgatttta
//
LOCUS       DACDAF010000115         6276 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.121, whole genome shotgun sequence.
ACCESSION   DACDAF010000115 DACDAF010000000
VERSION     DACDAF010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.121"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(99..1229)
                     /locus_tag="IVZ69_002508"
     CDS             complement(99..1229)
                     /locus_tag="IVZ69_002508"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HAP8184536.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKE
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     gene            complement(1878..3080)
                     /locus_tag="IVZ69_002509"
     CDS             complement(1878..3080)
                     /locus_tag="IVZ69_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8184537.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="IVZ69_002510"
     CDS             complement(3140..3343)
                     /locus_tag="IVZ69_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP8184538.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="IVZ69_002511"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="IVZ69_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
     gene            4880..5692
                     /locus_tag="IVZ69_002512"
     CDS             4880..5692
                     /locus_tag="IVZ69_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8184539.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
BASE COUNT         1862 a         1285 c          996 g         2133 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaatttctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcattcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggtgcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcataga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttc
//
LOCUS       DACDAF010000116         5874 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.122, whole genome shotgun sequence.
ACCESSION   DACDAF010000116 DACDAF010000000
VERSION     DACDAF010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.122"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            196..921
                     /locus_tag="IVZ69_002513"
     CDS             196..921
                     /locus_tag="IVZ69_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184540.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHSQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWRLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            911..1420
                     /locus_tag="IVZ69_002514"
     CDS             911..1420
                     /locus_tag="IVZ69_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184541.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(1490..2938)
                     /locus_tag="IVZ69_002515"
     CDS             complement(1490..2938)
                     /locus_tag="IVZ69_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HAP8184542.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(2938..3654)
                     /locus_tag="IVZ69_002516"
     CDS             complement(2938..3654)
                     /locus_tag="IVZ69_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HAP8184543.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAAVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            complement(3635..3985)
                     /locus_tag="IVZ69_002517"
     CDS             complement(3635..3985)
                     /locus_tag="IVZ69_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HAP8184544.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            4129..4902
                     /locus_tag="IVZ69_002518"
     CDS             4129..4902
                     /locus_tag="IVZ69_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP8184545.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMDNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            5073..5439
                     /gene="ssrA"
                     /locus_tag="IVZ69_002519"
     tmRNA           5073..5439
                     /gene="ssrA"
                     /locus_tag="IVZ69_002519"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(5744..>5874)
                     /locus_tag="IVZ69_002520"
     CDS             complement(5744..>5874)
                     /locus_tag="IVZ69_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP8184546.1"
                     /translation="QVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
BASE COUNT         1706 a         1143 c         1023 g         2002 t
ORIGIN      
        1 aaaattattg tcgctgctcc tcttttcgaa taaacagtgt tcaaaagctt gcatctacgg
       61 taatagaata gggcagcttc ttcacaacct cttgcttttt acaaaatatt ttctggtttt
      121 aattcgtgat ttcactaaag gaatttcata ctttattcat attcattttc tatacttttt
      181 atagaggtga aaagtatgaa aataatccgc tatgctactg ctcgattaat ttattacaaa
      241 aagcagacaa tactctattg tttattttca agcttttctg cttttttatt gatagcatgc
      301 ctgactcttt accattcgca atcggcttta gccaatcaag tccaagatcg gctttcattt
      361 attggcgctt ctgcatctac agagcttctt ccggctttag aattagctag ccgattttat
      421 ataaaaggca tattcagttt attttttcta tttgccttcc tttttatctt tttcttttac
      481 tattcagtca ggcaaaacaa gcaggaattg atcaattggc gcctgactgg tctttctaaa
      541 accaaattat tcctttttat tttctggcag ctgttctttc ctctctttct ttgttgtatc
      601 ttggttttat tgtggatcgt cagcttccag tcagtttatg aagcgcttct tcaaaggatc
      661 aattttcttg tcttaaagac tactgaactg ccagatatcc gtgatatctt gacttcggta
      721 agcggactta caattccgat ggatcaacag acttttttta ccatcgattt ccaaaatgat
      781 ctttttttca cagatatact taagggattt gcccaaactc ttattgggct cagtggatgc
      841 tgtctcattc ttagtctatt ccctttcact ttttttatcc atcatttgca aagtaggagg
      901 cctggacgta atgaaacctg aatatttgat tcatgctgaa cacttgaccg ttattttgtg
      961 tcctctcgaa aaacagcata aaatattgga gcacttgaaa aaagaggttc ttgttgcaaa
     1021 actggataat tttgcgatca tccaaaaaaa ttggccgatg tttccttatc tgaatcttaa
     1081 agaccatgtc ctgttggatg taccggaaaa agaaatcaaa caagatcgtt tggcctatca
     1141 agaaaaactt gatatctctc cttccttgct taattgtgcg gcagctgagt tgacgtcttt
     1201 tgaaaaagta aagctgcaat tacttcatgc cttgctttcc aagcgaaaca atattgttat
     1261 tgaagataca tttgatgaac ttagtgtatt ggagatccaa gagctactcc acttgctttc
     1321 ttatttagct catgaagaaa atcaaggtat cttactcttt actcatgatg ctactattgc
     1381 tcaaagtcct tatattgatc gtttagagcc cgcgggctaa atcaatcatt ttatagtaaa
     1441 aacaagcggt atagaagatc gattcatgat cttttatacc gcttgttttt tactcttttt
     1501 tgatttctac gtcaggcaaa cgaacagcga attttgttcc ttttcctagt tcgctttcta
     1561 cttctaattt tcctttatgc aagcgtacaa gttgctgcac gattggtaaa cctaatcctg
     1621 attcaccata ttttgtattt tttcttgaag gatctacttt ataataacga tcccagatac
     1681 ttttcatttg ttgttcagac attccaattc ccgtatcttc aatcgtgatg atcgtttcaa
     1741 gatagccttt ttctaaagta atcgtgattt ggccgttttc agtaaactgt atcgcgtttt
     1801 gaataatatt gaccatgatt tggacaaatc ggtcataatc agcgtaaaca tcaatatcat
     1861 caacggcttt caatgtcaat gtatctcctg ctgcttctgc tttagcttct aactgtgcaa
     1921 caatattttt caatgtttct gttccattga attttttaat gaccatactg atttgattcg
     1981 tacggatttt ttcataatcc aagttttcat tcaccaaacg gatcagacgc tctgtttcat
     2041 ttttcatcaa tttaatcgcg ttttctcgct gattttcagg gattgcattg tattctaacc
     2101 cttccagaag tccgttgatt gtcgtaagag gtgttctcat ctcgtgagaa gcatctgcca
     2161 taaattgtct tcgacgattt tcttgttctt caatttctgc ttgagattct ttcaatgaat
     2221 tcgtcatttt attgaaatca tctgctaact catcaaattc atctttgtca tgtacgggga
     2281 gctgtacatc aaaattacca ttcgtcactt ctttcgtcgc attccttaac cgattgatac
     2341 gcttaacttg gaatgctgca aaagcatagc tggcaataac tgcaacgata ctggaaaaaa
     2401 taaatccttt gaacaggttc agtgtaattg gacgaacgct gttatcgata tttcgcgcag
     2461 gttgactaac tacaagtgct ccatagaatt catgattcaa attaaatggc acaagtgcgt
     2521 aagaggtcgc ctgtgcttgt cctaaaatat ttttattcga tgtgaatttt tcttgacgtc
     2581 cattcctcag atttttccat tgatcagctg ttaaggtaaa attcagtaaa gctgtattag
     2641 tcggataaat gacacgttcg tttttatcga taaatataaa gttcacattt tgttctgtca
     2701 gtacttgctc tgtcagcagc aatgcatttt gaaacgcctg atcttgacta aactgcggga
     2761 gcgtatcggc ataggtttgc gttgtctttt caactgattc agcatatcca aacagttgct
     2821 ggtaattgtt ttcttcaatc gtttgttttg tcagttgtgt aaaagaaact ccaacgatca
     2881 ataagatcaa cgcgaccatt ccgcaaaaag ctaagagttg ctgatacaaa taacgcatta
     2941 ggcaacacca gaatcatcga atttgtagcc gactccccaa acagtttgga tgacttgtgg
     3001 tccgaccttt tcgatttttt gtcgtaattt cttgatatgg gcgtccactg tccgttcatc
     3061 accaaagtac tgataatccc agactaattc aagcaactgc tcccgagaga atacttgacg
     3121 tggttttttt gctaaagtaa acaatagatc gaactcttta ggcgtcagtc cttcaattgg
     3181 ccggttgtcc agatacgctt ctcgtgtttt cgtattcatc ttgaaatgac tagtctcgat
     3241 atcaaaatga tcatctgaaa ctgctgcttc ttctcttgct tctgccaact cactacggcg
     3301 atgcaaagct ttcattcgag caataagcgt cagaggactg aaaggttttg tgacataatc
     3361 atctgccccc atctctaagc cgatcacctg atcgctttca gaatctctag ctgtcagcat
     3421 gataatcggc acagtacttg aaactttgcg gatctctctt cctactagca taccgtccag
     3481 tgtgggcaaa ttcaggtcta gtgtaatcat atcccaatgt tgtgggtttt ctaaaaaggc
     3541 atcgagccct tcttttccat catacttgaa agttgcttcc caaccttcat ttaagaaaaa
     3601 catctgcatc atttcagaaa cagattgatt atcttcaatc attaaaatat tcattatcgt
     3661 tccctccagt ttccaggtca tatttctgta atttcttttc tgtcataata aaaataggca
     3721 taattggaaa tactagcaga agcatttcaa tcagaaaata attcgtatgc ccagatgtct
     3781 ttaaataata gccgatcaat gccatcagta agcccataag aaaaaaccag tttccgcttg
     3841 tcttttgagc cagccgccaa tgagcgtctg tttttgcggc aagaggcgaa tgatacccat
     3901 aaaaaggcag atttcctttt gagggcagaa tccgaaaaag actgccaatt attaagaata
     3961 agataccaat actgaaaaaa atcattcttt ccctcctaaa ttctcttctt atagtatact
     4021 ctaaattgtt gactgaacca atatgttcag gaattcttca cgaaaggttt gtcttttgtt
     4081 cattctttgt taagataaac ttattccaat aaaaaaggag ttttatttgt gtcaaattat
     4141 cgtgcaatca ctttctttga tcttgatgga acattactag atgcgaaatc aaaaatcaca
     4201 cccgaagtgg caaaagctat gaacgcatta aaagaaaaca atgttctccc cgtcatcgct
     4261 acaggacgta cagaagcaga aatccactct atcatggaag atgcgggcat tacttctgcg
     4321 gtcaccatga atggttcttt cattcgagta gacggcgaag aaatctattc tcaaacattt
     4381 tcttcagaag aatgtcaaaa aatgtatgat catgtacagt tgaacggtca tgaactttct
     4441 tactataacg atcagaaaat ctggtgtacc ggtcatagcc aaacaatgat caatgcttac
     4501 gacttcattc attcagatgt tccggaaatt gatcctttag gctttaaaga aaacacagta
     4561 aatatgttgc tgatcttatc tcaatcaggt gacgaatact atcacgaaca ttttcctgag
     4621 ctaacttttt atcggaatgg tccttactcg atcgatacag tgaagaaagg aatctcaaaa
     4681 ggggcaggtg tcaaacgtct gcaaaaagaa cttcagctgg aaaaagttcc tacttttgga
     4741 tttggcgatg gtccgaatga ttttgccttg ttggaagctt gcgacaacaa aatcgctatg
     4801 gacaacgcct atgacggatt aaaagaactt tctaccttta tcacaaagaa aaatacagaa
     4861 ggcggaattg tccacgcatt gaagtatttt gatctgattt aagatctttt tttgaagcta
     4921 cctcttttct taagaaaatc gcttattttt tcttaagaaa ggggcagtta ttatataaat
     4981 aatgggatat gattcgcttt tttattgaat ttatcccaat atatgctata ctaattttgt
     5041 atgaaaaata cacgtaaccc ttgttagcta acggggacgt tacggattcg acaggcacag
     5101 tcgagcttga attgcgtttc gtaggttacg tctacgtaaa aacgttacag ttaaatataa
     5161 ctgctaaaaa cgaaaacaac tcttacgctt tagctgccta aaaacagtta gcgtagatcc
     5221 tctcggcatc gcccatgtgc tcgagtaagg gtcctaactt tagtgggata cgtttcaact
     5281 ttccgtctgt aagttgaaaa agagaacatc agactagcga tacagaatgc ctgtcactcg
     5341 gcaagctgta aagtgaatcc ttaaatgagt tgactatgaa cgtagatttt taagtggcga
     5401 tgtgtttgga cgcgggttcg actcccgccg tctccatata tgtatggttg agacagataa
     5461 acatgtatga aaaacgttgt taaatcaacg tttttttatt ttggtcaagg agagaaaagt
     5521 agagaaatac aaaatttttt gcattgattt tgcattcaaa aaaacattca aacatttaga
     5581 aatccccaat acgtattcag gaaaatctat tttaaggttt acaaaaagaa cttttgttcg
     5641 tacactcttt ttgaggtgaa cttttatgct gatggaagga aaaacacaat tatggtttaa
     5701 gcatgttcct tcaaataagt ttttttaatt attatttgtc aaattaagcg agacaaaact
     5761 ttccatttac gtaactcaaa aaaacttcta atggtgtttg gtaatttagt gattttctag
     5821 ggatatggtt tcttttggac gcaacggatg agatgaatcc ttgattgact tggt
//
LOCUS       DACDAF010000117         5689 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.123, whole genome shotgun sequence.
ACCESSION   DACDAF010000117 DACDAF010000000
VERSION     DACDAF010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5689
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.123"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(488..1297)
                     /locus_tag="IVZ69_002521"
     CDS             complement(488..1297)
                     /locus_tag="IVZ69_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HAP8184547.1"
                     /translation="MVKESVIGKKELRSIFWRSFFMQSSWSFDKMMAYGQMNGIERSL
                     RKIYPNDDDYYTALQRHTETFNITPHIAPFVMSLSVTMEEENAKNPEFDTDAINKIKT
                     GLMGPLSGIGDSFFWGTFRVIAAGIGISFAQQGNILGMILYFTLYTAIHFIFKWLATK
                     YGYVLGTKFIDDTEDNHMIDKLSHGASILGLTVIGAMIGTMVTLNTSLKFTVGGAETS
                     LQSIFDQIFPGLLPLGITFLCVWLYSKGHKTITIILGIFVLCFLGTLGGIF"
     gene            complement(1297..2043)
                     /locus_tag="IVZ69_002522"
     CDS             complement(1297..2043)
                     /locus_tag="IVZ69_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HAP8184548.1"
                     /translation="MIQAILIALVAFLASIDEYTFGASMMGRPLFTAPFVGLILGDLE
                     SGIIIGATLESMFMGSIMVGSATPPEVYASSVLGTAIAIQSGQGVGTAVALTLPLSIF
                     LQMWRNFAYAMPITYFNNKMDEALVNHDFKKAQKYHYVAQPLIVGVPSAILVFVATYF
                     GVSTINAMIKLIPQVVLDSFDVAAGVLSCVGLALLIKMMANKAMMPYLFLGFVGVMYL
                     KMDVVGVAVVGLCLALLAVQKLTFEEEEDL"
     gene            complement(2061..2528)
                     /locus_tag="IVZ69_002523"
     CDS             complement(2061..2528)
                     /locus_tag="IVZ69_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HAP8184549.1"
                     /translation="MIKLLRVDERFVHGQVAFAWTNNLGANCIFVASNEIATNNLRKK
                     TLKMAVPTGTKFVVKDMTEAISVLNGEKIKKYQVFLIVGTVEDAYEITQHVPEIKEVN
                     LGNLKKNENRKMITSSVYLNEQELDLVKKMTENGITVQCQAVPTDKKINPLHD"
     gene            complement(2528..2938)
                     /locus_tag="IVZ69_002524"
     CDS             complement(2528..2938)
                     /locus_tag="IVZ69_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HAP8184550.1"
                     /translation="MRKIVIATHSMMAKGLKDTLEFIIGPQKSLLAITAYIDSDYSIN
                     QEIEQLFSDLAPDDELIVTVDLLGGSVSNAFSEQIGKDNFYLISGVNLPLLLELCLSG
                     EQDTKKLIQKAMNSGNEGIVLVNELLEKTEEDDF"
     gene            complement(2949..3962)
                     /locus_tag="IVZ69_002525"
     CDS             complement(2949..3962)
                     /locus_tag="IVZ69_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009141002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP8184551.1"
                     /translation="MLGFSEERFLSVLNGAVKNIETINQVADAISEKGFKNLYLVGSG
                     GTYATISPLAYLLSTHSELDYYHEIAAEVVCSQPKKINKDTVLITSSLTGTTQETVDV
                     VKYANSQGATTIAFVGNAATPLGEIVDYAIENDADNDTLVEELQLQFFALGARLMKNN
                     GEFPEYDEFIQTLQKMPEVLLSVRQQNDQKALEFAEKHKNTEFHMFVGAGNTYGAAYE
                     YAMCVLEEMQWIATKSIHAAEFFHGTIEMTDKSMSFVLLKGEDQTRPLVDRVERFVNK
                     YSDVVTVFDTADFELAGVPSAMRQYVAPMVMATALERVSAHFEKVRDHSLDIRRYYRT
                     VEY"
     gene            4179..4913
                     /locus_tag="IVZ69_002526"
     CDS             4179..4913
                     /locus_tag="IVZ69_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8184552.1"
                     /translation="MNTEELTNKLIQDIEQEKYKYAQAIPSERDFVQIYEMNRSAVKK
                     AIQQLVNKEYLLKIHGKGTFVKKNIHEHLQIKFHGLSELLEREGIQPSSLILASEIKP
                     AGHIVGKALQLEPTEEVFHLVRLRSGDGEPISIEDTYIPLNLIPDLQAFDFQIFSFYS
                     TLAAYHYQIENIYQTISSSKVSNKEARLLKTSLNRPVISLAITAVTTNEQAVEYTEVV
                     VLPEFAAIYTKNVHQGKEMKIYAQID"
     gene            4897..5607
                     /locus_tag="IVZ69_002527"
     CDS             4897..5607
                     /locus_tag="IVZ69_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8184553.1"
                     /translation="MPKLINLLAYDLIDKIIAYIHEHHLTPGTKLPSERDLSEMFNVN
                     RTTLRGALQKLVDNGTLRAQTNSGYYLTAPKFEKNAHHFFTPIEDSLLSKQRLQLKAT
                     ALSPKKAAALCPELNDFKQQQPQAYLEYIDAEAISLMLLIPMETLKKSNFSDNPFQDF
                     KSLAYTRSQEISLITDNDVAADLLGVDKEEVLLFVREEIRAGKELAAIALGYTISRRC
                     NIQVNVATTLQSGSVAKF"
BASE COUNT         1832 a         1195 c          943 g         1719 t
ORIGIN      
        1 aagcgacaaa aaccacgagc aggtccattc atcctcaaac ctcggtgatc ttcgcggttt
       61 aacaccatca gaagaaatgc acaaaaataa taaggagagt ctgagacata aataaattcc
      121 cagactttta gtgagtctaa atccgaataa acggtgggtc gaaagcaact ctagctgcgc
      181 gtcgatcgca gcaatctcta ggtgctatgt tcggataaat ggtggtcaaa agtcagattt
      241 tcggccattt cgtaacagcc aaccagacaa aaagcgtctg ttttgtcttc tactccaatt
      301 gctcaaatct tagcgacttt tggcttggtc ttactctaaa cagtttgtaa gcctaaactt
      361 tatttgctgt ttgtttctaa gatcaaagca aaactacttt ttagttggtt acttttacaa
      421 gttcttttta ctgttgaata aatgtaaatc ttaagaacaa atatttactt ctataattcc
      481 aagtttctta aaaaattccg ccaagtgtac ctaaaaagca taaaacaaaa attcctagaa
      541 taattgtgat cgttttatgc cctttggagt aaagccagac gcataaaaag gtaattccta
      601 atggcagcaa gcccggaaaa atttgatcaa aaatactttg taatgaagtt tcagctccac
      661 caaccgtgaa ttttagtgac gtatttaaag taaccatcgt gcctatcatc gcgccaatta
      721 ccgttaaacc taaaatcgaa gcaccatgag ataatttgtc aatcatatgg ttgtcttctg
      781 tatcatcaat aaatttagtt cctaaaacat agccatattt tgtcgccaac catttaaaaa
      841 taaaatgaat ggcagtatac aaagtaaaat aaaggatcat gcctaaaata ttcccttgtt
      901 gagcaaaaga aatacctatg ccagccgcaa taacccgaaa agttccccag aaaaatgaat
      961 cgccaatacc tgataaaggt cccattaatc ctgttttgat tttattaatt gcgtctgtat
     1021 caaattcagg atttttagca ttttcttctt ccatggtgac ggacaagctc ataacaaaag
     1081 gcgcaatatg cggtgtaatg ttaaatgttt ccgtatggcg ctgcaacgct gtataataat
     1141 catcatcgtt cggatatatt ttacgtaagg aacgttcaat accattcatt tgtccatatg
     1201 ccatcatttt atcgaaggac caagaggatt gcataaaaaa ggagcgccaa aatatacttc
     1261 ttaattcttt tttcccaata acactttctt ttaccattat aaatcttcct cctcttcaaa
     1321 agttagcttt tgaacagcca gtaacgctaa gcaaagtccg acgacagcca caccgacaac
     1381 atccattttc agatacatta cgccgacaaa tcctaagaaa agataaggca tcatcgcttt
     1441 attcgccatc attttaatta ataacgctag cccaacacaa gaaagcacac cggccgcaac
     1501 atcaaagctg tccaatacaa cctgaggaat caacttgatc atcgcattga ttgtagacac
     1561 accaaaataa gtagctacaa aaactaaaat ggccgatgga accccaacga ttaaaggttg
     1621 agccacataa tgatattttt gtgctttttt gaaatcatga ttgactaatg cctcatccat
     1681 tttgttgtta aaatacgtaa ttggcattgc ataggcgaag ttacgccaca tctgaagaaa
     1741 gatggacaaa ggtaaagtca acgcaacggc agttcctact ccttgacccg attgaatcgc
     1801 aattgctgta cctaaaacac tggaagcata aacttcaggg ggcgtcgcac tccctaccat
     1861 aattgagccc atgaacatgg attccaaggt ggcaccaata ataattcctg actctaaatc
     1921 tcccaaaatc aaaccgacaa aaggcgctgt aaatagcggt ctacccatca tcgatgcacc
     1981 aaatgtgtat tcatcaatag acgccaaaaa agctaccagt gcgattaata ttgcttgtat
     2041 catattcttc ccctcctctt ttagtcatgc aaaggattga tttttttgtc cgttggtaca
     2101 gcctgacatt gaactgttat cccgttttca gtcatttttt tcaccaagtc cagttcttgt
     2161 tcattcaagt aaacggaact agtaatcatt ttccgattct cgtttttctt taaatttcct
     2221 aaattcactt ctttaatctc aggtacgtgc tgagtaattt cgtaggcatc ctccaccgtc
     2281 ccgacaatta aaaatacttg gtatttcttg attttttctc catttaaaac agagatggcc
     2341 tctgtcatat ccttcaccac aaattttgtc cctgtaggaa cagccatttt tagtgttttt
     2401 ttgcgcagat tattggtagc gatttcatta cttgcaacga aaatacaatt tgcacctaag
     2461 ttatttgtcc aggcaaaagc aacttgccca tgaacaaaac gttcatctac tcgtaataat
     2521 ttaatcatta aaaatcatcc tcttctgttt tctctagcaa ctcgttcacc aaaactatcc
     2581 cttcattccc gctattcata gctttttgga ttagtttttt cgtgtcctgt tcacctgata
     2641 agcaaagctc taaaagcagc ggcagattta caccgctgat taaataaaaa ttgtctttac
     2701 cgatttgttc ggagaaagcg ttagacacgc ttcctcccag taaatctacc gtcacaatta
     2761 attcgtcatc aggcgctaag tcggaaaata gctgctctat ttcctggtta atggagtagt
     2821 cactatctat atacgcagtt attgctaaaa gtgatttttg aggaccaata ataaattcta
     2881 aagtatcctt taagccttta gccatcatgg aatgcgtcgc aattacaatt ttcctcatag
     2941 ctcttacctt aatattccac agtccgataa taacgacgaa tatctagtga atgatcccgc
     3001 accttttcaa aatgagcact cactcgttct aaggccgttg ccataaccat tggcgctaca
     3061 tactgacgca tagcgcttgg tacacctgct aattcgaaat ccgcagtgtc aaaaaccgtc
     3121 acaacatcgc tatatttatt tacaaaacgc tctacgcgat cgactagcgg acgcgtttga
     3181 tcttcacctt ttaataacac aaaactcata gatttatcag tcatttcaat agtcccatgg
     3241 aaaaattcgg ctgcatggat cgacttggtg gcaatccatt gcatttcttc cagtacgcac
     3301 atagcatatt cataggcagc cccataagta ttcccggctc caacaaacat atgaaattcc
     3361 gtatttttat gtttttctgc aaattcaagt gctttctgat cattttgttg ccgaacactt
     3421 agtaatactt ccggcatttt ttgtaatgtt tgaataaatt catcatattc aggaaactca
     3481 ccgttatttt tcatcaggcg tgcacccaaa gcaaaaaact gtaactgaag ttcttctact
     3541 aatgtatcgt tgtcagcatc attttcaatc gcataatcca cgatttcccc gagtggtgta
     3601 gcagcatttc ctacaaacgc aatcgtcgtt gcaccttgac tattggcata cttaacaaca
     3661 tcaacggttt cttgagtcgt accggttaat gaagatgtga ttaacactgt atctttatta
     3721 atctttttcg gctgtgaaca aaccacctct gcggctattt catgataata atcaagctct
     3781 gaatgagtgc ttaacagata agctagcggg ctgattgtgg catatgttcc accagagcct
     3841 accaaataaa gatttttaaa tcccttctca ctgattgcat ctgccacctg attgattgtc
     3901 tcgatatttt ttactgcacc atttaatact gatagaaaac gttcttcgct aaaacctaac
     3961 atagttaaaa acctccaagt caataatttg aaaaatatat ttgcaaatgc cggcacatta
     4021 acaaaccact taaccttttt tatataccac ctgttaacgt ttttaatgta ccacttatag
     4081 aaaacgctgt caatagtttt taaccacttt tatttttatt tgtaccaaaa tccttttttc
     4141 atgtataata aacaaaaata gactctggag tgtaacgtat gaatactgaa gaactaacga
     4201 acaaattaat acaagacatt gaacaagaaa aatataaata cgcgcaagct attccttcag
     4261 aacgtgattt tgttcaaatt tatgaaatga atcgttcagc cgtaaaaaaa gccattcaac
     4321 aattagtaaa taaagagtac ctactaaaaa tacatggcaa aggaactttt gttaaaaaaa
     4381 atatccatga acatttgcaa atcaaatttc atggtttgtc tgaattgttg gaacgggaag
     4441 ggattcagcc tagcagctta attttagctt cagaaataaa accggctgga cacattgtcg
     4501 ggaaagcttt acagctggaa ccaactgaag aagtatttca tttggttcgt ttaagaagcg
     4561 gcgacggtga gccaatttct attgaagaca cttatattcc attaaatctc atacctgatc
     4621 ttcaagcttt tgatttccaa attttttcat tttattccac attggctgct tatcattatc
     4681 aaattgaaaa tatctatcag acaatttcca gctcaaaagt gagcaataaa gaagcccgtt
     4741 tgttaaaaac cagcttaaat cgtccggtaa tcagccttgc tatcactgcg gttacgacaa
     4801 atgaacaagc ggttgaatac actgaagtag tggttttgcc tgaattcgcc gccatctata
     4861 ctaaaaatgt tcatcaagga aaggagatga aaatctatgc ccaaattgat taatctgttg
     4921 gcttatgacc tgattgacaa aattattgct tatattcatg aacatcattt aacccccgga
     4981 acaaaactgc cttcggaacg ggacctatca gaaatgttta atgttaatcg aactacctta
     5041 agaggcgcgt tacaaaaact ggtggacaac ggcaccttac gggcgcaaac caatagcggc
     5101 tattatttaa ctgcgccaaa attcgaaaaa aatgcccatc atttctttac accgatagaa
     5161 gattctctgc ttagtaagca gcggctacag ctaaaggcaa cggctctttc accgaaaaaa
     5221 gcagcagctc tttgtccgga actgaatgat ttcaaacagc agcaaccaca agcttattta
     5281 gaatatattg atgcagaagc aattagcttg atgttattaa tccctatgga aacattaaag
     5341 aaaagtaatt tctcggacaa tcctttccaa gattttaaaa gtttggcata tacgcgttct
     5401 caagaaattt ctttaataac tgacaatgac gttgcggcgg acttgctggg agttgacaaa
     5461 gaagaggttc tgttatttgt acgagaggaa ataagagccg gtaaggagtt ggcggcgatt
     5521 gctttaggtt atactattag tcgccgctgc aacatacagg ttaatgttgc tacgaccttg
     5581 caatccggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa taatagaaaa
     5641 agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DACDAF010000118         5534 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.124, whole genome shotgun sequence.
ACCESSION   DACDAF010000118 DACDAF010000000
VERSION     DACDAF010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.124"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            53..124
                     /locus_tag="IVZ69_002528"
     tRNA            53..124
                     /locus_tag="IVZ69_002528"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:85..87,aa:Gln,seq:ttg)
     gene            142..226
                     /locus_tag="IVZ69_002529"
     tRNA            142..226
                     /locus_tag="IVZ69_002529"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:176..178,aa:Leu,seq:caa)
     gene            481..1356
                     /locus_tag="IVZ69_002530"
     CDS             481..1356
                     /locus_tag="IVZ69_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8184554.1"
                     /translation="MKESASCFVLSYSGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAIEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            1460..2224
                     /locus_tag="IVZ69_002531"
     CDS             1460..2224
                     /locus_tag="IVZ69_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HAP8184555.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            2241..3653
                     /locus_tag="IVZ69_002532"
     CDS             2241..3653
                     /locus_tag="IVZ69_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8184556.1"
                     /translation="MNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADDMLNIPVIGAA
                     GNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMDPEVNMGIFGG
                     IISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAIFLGFIWPLIQIGI
                     DNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSPSKEVFRGEMT
                     RFINGDPQAGLFLSGFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMGSGAGTSFIAN
                     ITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVDYLINFRIATN
                     AILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEETELGLASKNYE
                     YMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISGIIKPTEKNYQ
                     IIIGLEVTYVMAEFNKLLEE"
     gene            3670..4994
                     /locus_tag="IVZ69_002533"
                     /pseudo
     CDS             3670..4994
                     /locus_tag="IVZ69_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005227470.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
     gene            5007..5465
                     /locus_tag="IVZ69_002534"
     CDS             5007..5465
                     /locus_tag="IVZ69_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP8184557.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
BASE COUNT         1846 a          831 c         1174 g         1683 t
ORIGIN      
        1 attgtggctc cggcattcgt gggttcgatt cccatcattc gccctttatt cttggggtat
       61 agccaagcgg taaggcaagg gactttgact ccctcatgcg ttggttcgaa tccagctacc
      121 ccagttatta tttttaaatt tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa
      181 tccagtgtcc gttgaggacg tgccggttcg accccggccg ccggtataat tatcaatata
      241 gcaactttct tatagagagt tgctatattt tttttgtttt tatgtaatta cctccaaatc
      301 aattcgatac aagtattatc ataaaacgag taaaaaagat attgataacg cttttattat
      361 gtgttaaact atttttgtaa attatgtagg gtgctactat tcaattaggc acgacctaag
      421 aaagggttct ttcttaggtc gttttttgtc tttaaaaatt gtttggagac aaaaatatgt
      481 atgaaggagt ctgcaagttg ttttgtttta tcatatagtg gaggtgaatt aacggtgtat
      541 gtgatgaaaa agctgaatca taatgctgta ttgatcgatg acgatggaat agaaaaaatt
      601 gcgatgggga aagggattgg cttttctgct aaagtgagta agccatttga tgttgaggat
      661 gctgacaaat tatttgtatt agattctaaa gaaaagatca aacgattcag tgagatagtc
      721 tcgcagattc caatcgaatt tatggatttt gcggaagaag tgattgaact gataacagct
      781 aggatctcct ctccattaga ttcaaatatc tatattacat tgacagatca tatttatttt
      841 gctattcaac gaaaaagaga agatagagat gtcacagcaa ttatgttgcc agaaatgaga
      901 ttcctttatc caaatgaata tgatatagca atagaagtgg tcgagcgaat caatcatcga
      961 tatcaaaccg agttagggtc aaatgaagta ggattcatca ctatgcatat cattaatgct
     1021 gagctaggag agcctaatag tttaaagagc ttaaaaatag tagaaatgac gaccacgatt
     1081 ttgtcccatc tagaaaaatc ctattcaaac gtttatgata aagaatcact gacttatcat
     1141 cgcttaatgg ttcatatcaa attcctggtt aaacgcttga tttatcagga agaaacgcca
     1201 gtagaaaata ttggtttttt tactgaaaca tttaaacata gcaaagcgta ttgtacagca
     1261 ctaaagatta aagatatcat cgaacagcaa tttcaacttg ccattcaaga aaatgaaatc
     1321 atctatttgg caattcatct agcacgaatc tattaaaata agggcgtaac tatctatagg
     1381 cgcaaccaaa tgacacatag taaatggact atgattattt ggttgcgcct attttagtag
     1441 aaaaaagaag gagaatgaaa tgggaaaagt gatttttaat tcggatgatt ttggctatag
     1501 ccatggtgtg aattatggga ttatggatgc ttatcagcga ggaattttga catcaactac
     1561 attgatggca aatatgccgg gtttcgagca cgctgtgaaa ctaagaaagg aaatgcctag
     1621 gctaggtgta ggagtccatt taacattgac gtgtggcaaa ccacttctca aaactgtcga
     1681 tactcttatc gaaagcggag agttcagatc cttatcttat tatcagcatc catttaacat
     1741 tgacaaagat caactgtatc aggaatggaa tgctcagatt caaaaaattt atcatgcggg
     1801 gatcatacca actcatttag acagtcatca tcatactcat actttggatg aaaaccagga
     1861 ggtagttgtt acattagcaa aaaaatatga tttgccggtt cggagcaact ttgaacgaaa
     1921 agatgaagtt cgtcatgtcg attattttga gccttgtttc gatgtcgtag gagaaactga
     1981 tgaaaaaaaa cgacaaatca atacgagtgt ggaagaatat ttggcaagtt tactcatgat
     2041 attgagagaa gataaaacga tcgaagtcat gtgtcacgca gcgtatttgg atcaggaatt
     2101 gttaaatggt tcaagttttg tgtatcctcg tactcaccaa gtcgaatttt taattcattc
     2161 agcatttgct caaaaagtga aaaatgatcc tttgattgag ttagtaacat atgaggatat
     2221 ttaatagagg aggaataaaa atgaatgtta aatcaaatgt gcagaagctt ggaagagcga
     2281 tgctacttcc agttgcagcg atgccattag cgggattgat catgcgttta tcagctgatg
     2341 atatgctgaa catcccagta attggtgcag ctggaaatgc cgtttttgga aacttggata
     2401 tcttatttgc tataggagtt gcaatcggtt ttgtcaaaaa taaggacaaa ggaatacctg
     2461 cacttactgg ttttttagcg attgctacct tgaaaaaagg cttagaaatc atggacccag
     2521 aagtgaatat ggggattttt ggtggaatta tttccggttt agtagcggca tggacgtata
     2581 atcgctttaa agaacaaaaa ttaccagtag ttttttctta ttttgcgggc gaaaaattcc
     2641 cattgactat ggtgatgatt ctacaaacaa tcgcagctat ttttttgggc tttatctggc
     2701 cgctcatcca aattgggatt gataattttg caaaactgct cgttgatatg ggggcattag
     2761 gtgtggggat atttatgttt ttgaatcgtt tgctgatccc ctttggactg caccatgtgt
     2821 tgaatacgta tatttattac gatttaggaa gctatacatc tcctagcaag gaagttttca
     2881 gaggagagat gacacgcttt atcaacggag atcctcaggc tggactgttt ttatcaggtt
     2941 tttttgtagt aatgatgttt ggtataccag ctatatgtct agctatctat aaagcagctt
     3001 ataaagaaaa taaagagatg gtcaaaggaa tcatgggaag cggtgcagga acttcattta
     3061 ttgcaaatat cactgagcct gttgaattta gtttcatgtt tctttctcct atgttgtacg
     3121 tgatccatgc actttttgcc ggtttagcag ggattgtctg ttacttattc aatatacgaa
     3181 ttggttttac attcggagca tgtattgttg attatctcat caattttcga atcgctacca
     3241 atgctatttt gattcttcca atcggaattt tcttttttgc cttgtattac gttacttttt
     3301 attatttgat caataagaga aacattcaga cattaggacg tgaagctaag gcagagtttg
     3361 gcaatgaagt aaccttagaa gaaacagagt tagggttagc aagtaaaaat tatgaatata
     3421 tggcaacaaa aatgctacaa gcgtttggag gaaaagccaa tatcctggat gtctatagtt
     3481 gtaatacacg cctacgggta gaggtagtgg atcccaccat ggtcgaggaa cagcgaatca
     3541 agcaattagg gataagcggg atcattaaac caactgaaaa aaattatcaa attatcatcg
     3601 gcttagaagt gacttatgtt atggcagaat tcaataaatt attagaagaa tagaaaggaa
     3661 aagatgatga tgaaaaaaca gattatcact atagctggag gcgggagtac gtatacacca
     3721 ggaatcgttc aagccatttt gaacaatgaa aaacggttgc cattatctga aatacgttta
     3781 tatgatattg atgaagaaag aaatatggat atgtacttga ttgttaaatt tatgctgaaa
     3841 aaaaaggttt ttcaaatatt cgcattcgtg caacggatga tccaaagctt gcttttacag
     3901 gatgcgattt tgttttctca caaattcgtg ttggaggatt ggagatgcga gaaaaggacg
     3961 aaaagattcc acttaaacat ggattagtag gacaggaaac gtgtggactc ggaggatttg
     4021 cttatgggat gcgctcaatc aaaggtttat tggaaattgt cgatcatata caagactatg
     4081 cccccaaagc atggattttg aattatacaa atccagagtc gatcgtttct gaagctgttc
     4141 gtcgtaaata tccgaatgta aaaatgatta atgcctgtga tatgactatt tcaattgaag
     4201 aaacgattgc agtgaattac ggttatgatc gtaagaattg gatcgttacg tattatggtt
     4261 taaaccactt tggctggtat acatcgattt atgataaaga attgcaacga gaaattatgc
     4321 cagagattat tgaaaaacta ataacaaaag aaatgcaagt cgccgatttt aatataggag
     4381 acaaaacttg gcaaaaaacc tttcaaatga tgtcagtcat cacgaaaaat tttccaagta
     4441 atatcccgaa taattactta gagtattact tatatcctga tatggtcgtt gagcatactg
     4501 acaaagagta tacacgtgct aatatggtca tggatggacg agagaaaaat accaaagaaa
     4561 tggctgataa aatacgccgc ggtattgtgg aagaagtatt gaactttaat tttggggagc
     4621 atggacaata tatcgtcgat atagctattt ccttgttgaa tgatgatcgt cgtcgcttta
     4681 tgctaatcgt tcctaatcaa ggggcgattc cgaatctacg gtcagatgca gttgttgaaa
     4741 taccggcata tgttggtgca actggtgtgg agacaattac actaagaaaa ccaatcagtg
     4801 attttcataa aggattgatg gaggcacaag ttgcagcaga gaagttacta gtagatgctt
     4861 actttgaagg ttcttatcaa aaagctttac aagcatttac attgaatcaa accgtaccaa
     4921 atgccagagt cgcaaaaaaa atactagatg aaatgatcaa agtaaacaaa aaatattggc
     4981 cagcattaaa gtagaggtga taaaaagtgc atttctttaa aacaagaaac attctaaaag
     5041 ctgtagctag tggtcaaatt attccattaa cagcagtaaa agacgaggtc ttttcttcaa
     5101 aaatgatagg agttggatac gctataacga atcatgatgg atatatccat gcgccagtta
     5161 aaggaataat cgataatata tttcctaccc gacatgccat aacgatcgaa agtgaatctg
     5221 gcagaaaaat actgatccat atgggtttag atacagttga actcgaagga agtccgtttc
     5281 agatacgggt tgaaagtaac caggaggtaa aagaagggac actgttagct attatagatt
     5341 tgaagaagtt ggagcaagca caaaaagata cggtgatcat tgtagtttct ccaggcattt
     5401 ttgaaggaaa tttattaaaa caaaaccaag aagtaaagat taaagatagt tgttttgaat
     5461 tttagtgtac gatgaaaaaa gttaaatagg gtgatattta tgggtgaatt tacaaaattt
     5521 ttttgaaatg ataa
//
LOCUS       DACDAF010000119         5263 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.125, whole genome shotgun sequence.
ACCESSION   DACDAF010000119 DACDAF010000000
VERSION     DACDAF010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.125"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            36..1043
                     /locus_tag="IVZ69_002535"
     CDS             36..1043
                     /locus_tag="IVZ69_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HAP8184558.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            1055..2059
                     /gene="neuB"
                     /locus_tag="IVZ69_002536"
     CDS             1055..2059
                     /gene="neuB"
                     /locus_tag="IVZ69_002536"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HAP8184559.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2056..3204
                     /gene="neuC"
                     /locus_tag="IVZ69_002537"
     CDS             2056..3204
                     /gene="neuC"
                     /locus_tag="IVZ69_002537"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HAP8184560.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            3177..3854
                     /locus_tag="IVZ69_002538"
     CDS             3177..3854
                     /locus_tag="IVZ69_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HAP8184561.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            3844..4986
                     /locus_tag="IVZ69_002539"
     CDS             3844..4986
                     /locus_tag="IVZ69_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HAP8184562.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            4999..>5263
                     /locus_tag="IVZ69_002540"
     CDS             4999..>5263
                     /locus_tag="IVZ69_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP8184563.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNI"
BASE COUNT         1951 a          680 c         1034 g         1598 t
ORIGIN      
        1 ttatagatga ctataattca taggaggaga tataagtgtt taaaggaaaa acaatattag
       61 taactggcgg aactggttcc attggaagtg aaattgttcg tcagctttta aaatatgaac
      121 caaaagctat cagaatttat agtagaggtg aagaaaaaca attttatatg caacaagagc
      181 tctcaaatca cactaatttg agatttttaa ttggtgatat cagagactct caaaggattg
      241 attatgcatg tcgtgatgtg gatattattt ttcatgctgc cgcaatgaaa cacgttccag
      301 caagtgaata taatcctatg gaagctgtaa aaacaaatgt gatgggaact caaaatgtaa
      361 tagatgcagc gatcaaaaat aatgtaaaac attttgtagg tatcagtaca gataaagtag
      421 tgagtcctac taacaccatg ggtgcgacaa agttattgag tgaaaaatta ataatagctg
      481 ccaatcagta taaaggaaaa acagaaacaa tattttcttg tgtaaggttt ggaaatgtca
      541 tggggtcaag tggatctgtt attcctcttt ttagtaaaca aataaaaaac aataaagata
      601 ttactttgac agatgttgat atgacacgat ttatgatgtc aataccggat gctgcaagat
      661 tagttctgtc tgctgctatg aattcaaaat ttggagaaac atatgtctta aaaatgccgg
      721 caatcaatat tttaacttta gctcaatcat taataaaaat atataatgat acacatgatg
      781 aaaaatatag aggtgaaata aaagttgtag gtatcaggcc aggagaaaaa ttatatgaag
      841 agctaatgac tacagacgaa attgaacgct catatgaaaa tgataaaatg tatatcattc
      901 caccacacta tcatgctact gacgaactgt acaaagatta tgaaaaaatt aaaatcactg
      961 catactcttc agatgcaaca gaattaatga gtggacagga atttattaga atcgcaaaag
     1021 agaataatgt cgtgacttgg taaggagttt tatgatgaaa tcagaagtat atgtaattgc
     1081 agaaattggt gtaaaccata atggaagtct agatttagct ttagaaagta ttgataaagc
     1141 taaagaatgt ggagctaacg cggttaaatt tcaaacattt aaaacgaata agctagtttc
     1201 caaaaaggct ccaatggcaa aatatcagaa ggataatctt aaagaggaca gttctcaatt
     1261 tgaaatgcta aaaaaattag aattatctca atctgatttt attagaataa aagattattg
     1321 tatacaaaat aaaattgatt ttttgtctac tccttttgat gaagaaagtg cagactttct
     1381 aaaacaaatt ggtgtacaag gatttaaaat tggctcagga gatttaacaa atttaccttt
     1441 tcttagaaaa atagatatgt atgggttgcc agttttatta tctacaggta tggctgatat
     1501 tcatgaggtc agtgaggctg tagattgttt catagatagt ccagttacta ttttacattg
     1561 tacttcaaat tatccggcta gttctgaaga tattaattta ttggcgatta acacattaaa
     1621 agaaatgttc gggatacccg ttgggtactc cgatcattca ttgggatatg atgttggtat
     1681 ttgtgctgtt gcgatgggtg ctaaggtaat tgagaaacat tttaccttgg ataaggaact
     1741 acctggtcca gatcataaag cttctttaga tcctcaggaa tttgcagatt ttgtaaagca
     1801 tattagaaac actgaaatat ttttaggtga tggtgttaag cgagcaatgc cttctgaact
     1861 tagtacaaaa gaagtatcaa gaaaaagcct agtggtcact gagaatttaa atgtgggaga
     1921 tattcttaca gagaaatctc ttacaataaa acgtcctgga aatggaatag ctcctaagtt
     1981 tttatatcaa tatattggca aaaaagttaa aagaccaata agtgcagata gtgttctgct
     2041 tgaggaagat gttgaatgaa aaaaatactt atagtaagtg gaacacgagc tgattatgga
     2101 atatataaac ctgttgctga gaatttacta caagataatt gggatgtatc atttgttgtt
     2161 tctggaatgc atttatccca taaatatgga tttactaaag aattgatctt agctgacgga
     2221 tttagaatta gtggagaagt tcaaagtttg tttttagaga acaataaggg aaacatggct
     2281 cggtctgtgg cattagagat aaatggtttc acaaatatat ttgaacaaac tagccctgat
     2341 tttgtattat tactagggga tagaggagaa atgttggcag ctgcgatagc ttgtttgtat
     2401 cttggaatca aaacagcaca tattcacgga ggcgaagtgt ctggtactgt agatgaatca
     2461 ataagacatg ccataacgaa aatagcatct gttcattttg ctgctacgga aaaaagcaaa
     2521 gagcgtttaa taaaaatggg ggaagattct tggagagttt ttcccgtcgg agctcctaga
     2581 atagatacta ttttaaataa tagattacct agttttagag atataaaaga aaaatatcat
     2641 ctaaaatttg aaaagaaaaa atacgttttg caagtatttc atccagttgt aaccgaacta
     2701 gaaaatatag aaaaacaaat tttagctttg atcaattcaa tggaacaaca atctcaacca
     2761 attatttgca ttttacctaa tagtgatgct ggtagcgaaa ttatcagaaa aatgtaccag
     2821 aaatatttaa aaacggatat tatttatatt acgaatttag agccggagga atacctgact
     2881 atattaaaag agtgcaaatt tatgatcgga aattcttctt ctgggataat tgaagctgca
     2941 tcattcaaaa taccagtaat aaatttagga accagacaaa atggacgaga acaatctaaa
     3001 aatattataa atgcaaatct aaatgaaaat gaaattgaaa ctgctttgaa taaaatacaa
     3061 gatcctcagt ttataaaaag cttgaaaaat gttaagaaca tctacggtga cggcaacagt
     3121 tctagaagaa taacaaaaac attgaatcaa atattgaatg atggggaaga tattaagtgg
     3181 attcaaaaac aaatagctta ttaaaatata ctagtgatcc atacattatt attggggctg
     3241 gcggacacgc aaaagtcatt attgaaacct taagattaga aaataagtta atatatggat
     3301 tttttgatga taagcaaaat aaaatgcaag atctgaaata tcttgggaaa ataaacgaat
     3361 tgaatagctg ggcggatagc aaaaaaaaaa tctataaatt tattgtagct attggtgact
     3421 gtgtagtaag aaaaaagatt ataaaaaaat tgaatatgcc aagtgagcaa tatggaatag
     3481 ctgttcatcc aagtgctata gtggcaaaag aaatttcaat tggttatgga actgttattt
     3541 ttgcgaatgc tgtaattaac ccagatgctg taattggaga gcatgctata ataaacacag
     3601 gtagcattgt tgagcatgat tgtagaatta ataactatgt tcatttatct ccaggtgtat
     3661 gcttagcggg tggagtacat gtaggtgtag gaactcaaat aggaattggt tctcaatgta
     3721 tccagatgaa gaaaattgga tcttggtgta tgataggcgc agggagcact attgttaagg
     3781 atattccctc acattcctta gcttatggca atccagctaa aattaagaaa gaaggaatta
     3841 attttgaatt ctagaatttt attatcaagt cctcatatgg gaggaacaga agaaaaatat
     3901 gttgctaagg cttttaaaga taattggata gcgccattag gtgaaaatgt ggataaattt
     3961 gaagaaagta ttacaaaata tactggttct aagggcggag cttctgcgtt aagttcaggt
     4021 acagctgcca tacatcttgc cttaagactg cttaatgttg gaaaaaacga tattgtcttt
     4081 gctccttcat ttacttttat agctacagta aatcctattt tatatcaagg ggctgtacca
     4141 gtgttcattg actcagaacc taatacatgg aatatgagcc ctgttgcact agagagcgca
     4201 ttagaagaag ctgaaagaaa caaccaatta cctaaggcaa tcatcgtagt gaatttatat
     4261 ggtcaaatgg ctgattatga acgaatttta gctattgcaa accaatttaa tgttccagtg
     4321 atagaagatg cagcggaatc gttaggttct acttataagg gaatttcgtc aggcttattt
     4381 gggacaattg ggatctattc atttaacggt aataagatca tcacaacctc aggtggagga
     4441 gctctagtgt ctagtgataa aaaatatgtt gagcattcaa gatttttagc aacacaagca
     4501 agagatcaag caccgtatta tcaacatagc gaaataggtt ataattaccg tctaagcaat
     4561 atttctgccg gtatcggacg tggacaaatg gaagtattga atgatagagt agctaaacga
     4621 agagaaattt tcaatcgata taaggaagct ttttctggaa ttgatagaat tgaaatgatg
     4681 ccagaagtgg atggcatggt gccaaatcgt tggttgtcta ctttaacgat caatgattat
     4741 aattctattg atcaagtagt taacgtaata aataaactaa atgaaaaaaa cattgaaaca
     4801 agagctttgt ggaaaccact acatttgcaa ccagtatttc aaggggtaaa aatgtattac
     4861 catgataata atcttagtgt gtcagaaaag ttatttaata gcggcttatg cttaccttct
     4921 ggaagtaata tgacagatag tgaacaagaa tttgttattg atgagtttaa aaaaatattc
     4981 aagtaggtgt gatattttat gaacatagga attattggtt taggttccat ggggaaaaga
     5041 agacttagac tcattcaaga acactttaat gatattttac tatgtggtgt tgatactaat
     5101 gaggcgagac gaaaggaagt tgaaaaggaa tttggaatac caacttataa tagtctaaca
     5161 gaggcaaaaa atttgtttga aataaattca gtttttgttt gtacatcccc tataacccat
     5221 gaatttatta taaaagaggc tttaaattta gattgtaata tct
//
LOCUS       DACDAF010000120         5231 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.126, whole genome shotgun sequence.
ACCESSION   DACDAF010000120 DACDAF010000000
VERSION     DACDAF010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5231
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.126"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            72..1361
                     /locus_tag="IVZ69_002541"
     CDS             72..1361
                     /locus_tag="IVZ69_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HAP8184564.1"
                     /translation="MRYSTILISTFAALSLSLTINQTVHTEEIETAKWTETKWANVNR
                     ITFQDEFSSFNSGVAKLRKGQTATIKAKIDYSGDLAPILQSAVTFENVDPALSIGYDE
                     NTLTIQHKQAIFTFTVTLNQDLLKPALFTVKVSDGLPNDHHHLTPYSQRQTIEQDSAI
                     DSGGDLVEEPTDKPENENKPEVPPTENPDGEQKPEIEPGEEPDTETQPEPDNESKPEI
                     TPGEKPDVDPEEKPDVTPEPDTDSGNQTVPETNPDTDNETENPEKPEAAPEEKPDVTP
                     EPDTDSGNQTVPETNPDTDNETENPEKLEVDPEEKPDVTPEPDTDARDQGIPEKINKK
                     TIQEDGKKESKKSNLAILKINEEQLNKKSRIFDSAQSAETLKSSKDTTFASPETKNKQ
                     LPKSGESQNKVILWSGIILLSIATMLSAKRFKQNRSL"
     gene            complement(1487..2566)
                     /locus_tag="IVZ69_002542"
     CDS             complement(1487..2566)
                     /locus_tag="IVZ69_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP8184565.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVIDFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVIALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(2675..3115)
                     /locus_tag="IVZ69_002543"
     CDS             complement(2675..3115)
                     /locus_tag="IVZ69_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP8184566.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTSLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTPQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(3172..3582)
                     /locus_tag="IVZ69_002544"
     CDS             complement(3172..3582)
                     /locus_tag="IVZ69_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HAP8184567.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(3763..4197)
                     /locus_tag="IVZ69_002545"
     CDS             complement(3763..4197)
                     /locus_tag="IVZ69_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HAP8184568.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVSFEERKQLFEKYM"
     gene            complement(4297..5145)
                     /locus_tag="IVZ69_002546"
     CDS             complement(4297..5145)
                     /locus_tag="IVZ69_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HAP8184569.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAVLGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLFFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFVFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
BASE COUNT         1925 a         1009 c          876 g         1421 t
ORIGIN      
        1 cagtaaacat ataggtagaa tctctactat cttatttctt gcatacaaaa aaatcaagga
       61 gtgagagagt tatgagatat tcaaccatct taatatcaac atttgcagcc ttaagcttat
      121 cgcttactat aaatcagaca gtccacacag aggagataga aacagccaaa tggacagaaa
      181 ccaagtgggc caacgtcaat cgaattacct ttcaggatga attttcatcc ttcaattcag
      241 gagtcgcaaa attaagaaaa ggacaaacag cgaccatcaa agcaaaaatt gactattcag
      301 gagacttagc acctatacta caatcagctg ttacatttga gaatgttgat cccgctttgt
      361 cgattggcta tgacgagaac actttgacta tccaacacaa gcaagcgata tttaccttca
      421 ccgttacatt aaatcaggac ttgttaaaac cagcgctttt tactgtcaag gtatcagatg
      481 gactaccgaa cgatcatcat catttaacgc cgtatagtca gcggcagaca attgagcaag
      541 attcagctat cgactcagga ggagatcttg ttgaagaacc aacagataaa ccagaaaatg
      601 aaaataagcc agaagtaccg cctacagaaa atccagacgg agaacagaaa ccggaaatag
      661 aacctggaga agaacccgat acagaaactc aaccagagcc agacaatgaa tcaaaacctg
      721 aaataacccc tggagaaaaa ccagatgtag acccagaaga aaaaccggat gtgactccag
      781 aaccagatac ggattctgga aaccaaacag taccggaaac aaatccagac acagataatg
      841 aaactgaaaa tccagaaaaa ccagaggcag ccccagaaga aaaaccagat gtaactccag
      901 aaccagatac ggattctgga aaccaaacag taccggaaac aaatccagac acagataatg
      961 aaactgaaaa tccagaaaaa ctagaggtag atccagaaga aaaaccagat gtgactccag
     1021 aaccagatac ggacgcaaga gaccaaggaa taccagaaaa aataaacaaa aaaacaattc
     1081 aagaggatgg aaaaaaagag agtaaaaaat caaatctagc aattctaaaa ataaatgaag
     1141 agcagctgaa taaaaaatca cgaatatttg atagcgccca atcagctgaa accttaaaaa
     1201 gtagcaagga tacaaccttt gctagtcctg aaacgaaaaa taaacagcta ccaaaatccg
     1261 gagagtcaca aaacaaagtt atactgtgga gcggaatcat tctattaagt atagcaacaa
     1321 tgctttctgc aaaaagattt aaacaaaaca gatctctcta acatttgaat aatgtctgtg
     1381 aacgcatttt tcaaataaaa agaaatatcc agaaaacgac cccaaaatac cagattgaaa
     1441 tctgatattt ggggtcgttc atactttatc tttcttcata tttattttaa gggatatctg
     1501 tttcttttgg aagatggttc gggatctttt tcactttcaa tacatctaaa aagaaggtaa
     1561 agatcggaat gccgacaatc aagccccaaa cgccaaagaa ccgttcgcta acaagtaaga
     1621 ccacaaatgt ataaaaaatc ggcagttctg ttttgctgga catcaacttc ggattcagca
     1681 cataagactc aattagatgg acaatcaaaa tcgtaatcag gatataaaca acatctcgga
     1741 tgcctccttg ggaataagct atgaaagata gaggaataca agaaatgata acacctgcta
     1801 ctgggatcag acttaaaatg aaaatcatga tcgctaaact cagcagctga tgaaagccaa
     1861 atacagccaa ggcgattgta gtgagcaacg tgtttaaaag agcgataaca aattgagctt
     1921 ctaataccaa accaaatgta ttgacaaact tatcggcaaa atagtaaata tcttgaaaga
     1981 accaagaaaa ttcacttttt aaaaacaatc ttgagaatac aattgttttt ttcttttcaa
     2041 tcataaaaaa gaaacttaag atgaatgaca tagcaaacgc cactgccatt tttcctatat
     2101 cctgtaaata gccaagcgca atcgaagcgc cattttgaag ctgttcaaaa aaatcgtttc
     2161 gctcaatata agtatggata tattgtaaaa caggatctgc atcttttggc tgatgctcgt
     2221 aaaaatcaat aacggactgg atcatatcaa atgtttgatg aataagcatc gggatatact
     2281 ttgtgaatgc cagatagata aggtaaacga tcagtgtata aatcatgata gctaaaacac
     2341 ctgtagggat tcggacaaat cgctgaatga tttgaacaag atgaatcatc aaataagtaa
     2401 agataaatgt gagcaaaatg gttgtaatca tacttctaac taagaaaaga acaaaaacga
     2461 caaataataa aacagtgaga cggcgtattt tttcattcgc caaaaaacgc tgataaacgg
     2521 tcaaatcgac aacctccaaa taacaaaaaa taaacacgtt attcattata tgatggaata
     2581 tgaaaataag aaagagaaag agcaaaaaga aaaaccgcta aatgacgtta tcttatgagt
     2641 tggttttcct cataaaatcg ttcatctagc agtttcagcc ctttttctgg tcttgatgaa
     2701 aattatctag catttttcgg gtcagatgtt gcagtgtatc caattcttcc tgttcaagtg
     2761 gaagataaga cttgatcttt tgtggaatac cttctgcttg tttttgcaac gcagcacctt
     2821 gaggagtcag cgtaacattt acgattcttt catcacccgt ttcacgctga cgattaatat
     2881 aatttttttc tgctaacttt tttagtaagg gagtcagcgt accagaatcc agacacaaat
     2941 catttcctag ctctttcact gaagtctttt tcttttccca taaaactaac atcacaagat
     3001 actgggtata ggtaagattc agcggcttga ggagggaagt gtagtgtcta atgatttcct
     3061 tagaggcggc atataaagga aaacatactt gattaactaa atatagatct tccatttttc
     3121 cacctccgct gttttactat agtgtatcat agcggattta cacaaaaaag tctattcact
     3181 aactgctttc agagtaactt ctatatttcc agctgtagct tttgaatacg gacacacttt
     3241 atgcgctgcc tctaataatt cttgcgtttc ttccagagaa agaccttcga tagatccttc
     3301 aatctctaca cctaagacaa agctcgtttc actttctgaa taaagggaaa cttgtgcact
     3361 gacagtagaa gccccagaga tatttttttg ctgtttgatc aattctaatg cactgttaaa
     3421 acatgcactg aaaccagctg caaacaattg ttcagggttg gttgcatttt cgacgcgttt
     3481 accaggagct gcaatattca attcgaatgt acgatcggga ttatgaactt ctccagagcg
     3541 tccgcctgtg ttgatcattt tcgtagaata catttttttc ataaaattac cacctttaat
     3601 tatattttat acaattgaat tttacacaat ataattgtgg aaagcaaaga aatggattgg
     3661 cataagataa ataagagaaa gcacatgaaa cagacgcgct ttctcgaata gcaaacatat
     3721 acaaaaaaat atcagagaca aaaactaatc tcatcataaa cattacatat atttctcaaa
     3781 aagttgtttt ctttcttcaa aacttacttc acgatggacc tgatgaagca tccataaata
     3841 accaaaagga tctctgaaca ttgagttagt cacaccaaag tccatcattt ctgtcatttc
     3901 ttgaatctct acacagccat ttcgtaatgc tttattatgt gtgtcctcga tatcagagac
     3961 gatgatattg aaccagatcg tatttggatg ttcagcagta ggagcagtca aaccaagaga
     4021 cgtgttttca tccagcatat ggaatctcgt gccatacaag gtaaaaatga cttcattatt
     4081 gcctctaggg taatctgttg cctcaatcag ttgtatttca tcaaagattg tttgatacag
     4141 ttctagtgct ttcaaactat catttaatac aaaatctatt tccgttcctt tatgcataaa
     4201 gatctcctct ccttttcagt cgaacagtta ctagattctt ttattatacc agttaaagaa
     4261 aacgcattca aaaaaatagc ggatttactt accaactcat tcgattggat gataagtaaa
     4321 tccgcgtccc attacttctg ctacgctgct gacaatgaca aaggcacttg gatcgatttc
     4381 ttctatcaat ggtttcattc gggaaaattc atgatcagtc acaacgatca ataaaacctc
     4441 ttttgacttt cgattatacc cgccttttgc ctctagcagg gtaaggccac gtccaatctc
     4501 agcacttaag cgaaggcgga tgtcttccaa ataatgttca ctcatgacca taacagattt
     4561 ctttcgattg atacctgttt cgatataagt catgacaatt gaagtgattg caatagataa
     4621 aatagcataa agaaactctt ctattccaaa aacaaacaga ttaagagaaa caacgaatgc
     4681 gtctgtaaaa aataagccaa tcgaagtatt caagtggaaa tattttttaa aaatgagggg
     4741 agggatcgtc gtaccgccgc tagaagagtt gtttttatat aaaatcgcaa ctcctaaagc
     4801 aaaaatcgca cttccaaaaa tgacagacaa caaccgatct gaagtaatca ttgtttctgg
     4861 aactattgca atgattaaag gaaaaaacaa gcttccgaaa agtactttaa aaaagggttt
     4921 tttacctaaa aatagaagag ctagtaccaa cataacgata ttcaacacta aaataactat
     4981 agctcggtca aatcctaaaa cagcttccag taatattcct agaccgctga cacctccagc
     5041 agcaatatga tgaggcccta aaaacatatt gatagcgact cctaatatga agagggcaaa
     5101 aataatctta atgtatgtcc atataaattg tctcgtttct ttcatttatc cacttcctta
     5161 attcattaat aatactctta tcttattata acttactttt caccttaagt taactttaat
     5221 taataaaaaa a
//
LOCUS       DACDAF010000121         5210 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.127, whole genome shotgun sequence.
ACCESSION   DACDAF010000121 DACDAF010000000
VERSION     DACDAF010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.127"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(45..992)
                     /locus_tag="IVZ69_002547"
     CDS             complement(45..992)
                     /locus_tag="IVZ69_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HAP8184570.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1170..1973)
                     /locus_tag="IVZ69_002548"
     CDS             complement(1170..1973)
                     /locus_tag="IVZ69_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HAP8184571.1"
                     /translation="MTTKQLIISSFIRFKDLKESRNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2119..3033
                     /locus_tag="IVZ69_002549"
     CDS             2119..3033
                     /locus_tag="IVZ69_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HAP8184572.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3081..3551
                     /locus_tag="IVZ69_002550"
     CDS             3081..3551
                     /locus_tag="IVZ69_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HAP8184573.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3636..4244
                     /locus_tag="IVZ69_002551"
     CDS             3636..4244
                     /locus_tag="IVZ69_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HAP8184574.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4378..4578
                     /locus_tag="IVZ69_002552"
     CDS             4378..4578
                     /locus_tag="IVZ69_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HAP8184575.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1714 a          795 c         1023 g         1678 t
ORIGIN      
        1 ttgtcacctt ctcttttttc ttttgaaaat attgttttca gctattaata tcctgcagac
       61 aattttactt gattggtttg aagctcatgg gtggcaaagt agcttttcag attggttaaa
      121 aaaatagcca ttaatttctt ttgaaaatca ggtgtcaaac ctgcaatgtg ggaagtaatc
      181 agtacattgt ccattttcca aagaggatga tcttgtggaa gaggctcttc ctcaaaaacg
      241 tctaatgctg caaaggaaag ttgctggtta tttaaagcct gcaccagatc ttgtgtctta
      301 acagaagcac cacggccaac attgatgaat acagattttg gatcaaagtg ttcaaacata
      361 tgctgatcaa agagcccagt tgtttcctcc gttagaggta agatattgac tacgaaatct
      421 acttcaggaa gaacttcctt tagttgattt aaagaaaaag tcttttccat tccttctgct
      481 ggatgaccgg atgtattgat tccatagcag ttcatgtcta atgctttgca tttttttgca
      541 atcatttttc caatatggcc agttccaatg attagtattt ttttcccttg gatagattgg
      601 taatggaccg atgaacctaa ccatttcatg tcactctgtg ccttttgtgc ttgaaaaaga
      661 ccacgagaat acccaaggat gattcctaag acatgctccg taatcgattc actgtggatg
      721 ccactaccat ttgaaagtaa aatatgtttc tttgaaaaag tctcaagggg tagctgatca
      781 acaccagctg agatagattg gacccatttc aaggtagaag aggctaatag tttttcttgg
      841 tagtctgagt tccagcccaa actgatctct acattttgta gatcctctgg ttgtaattct
      901 gttttaaaga tataaccagg cgctatagta tggatttctt cgataaattc atcacgaaat
      961 ggacgatctg cataaatgat tctttctgac atagttaatt tcccgccttt ctttactcta
     1021 agtgtagcgc atacaagaag aactttgaag cgccttgctt gttttttgag aaagaaatat
     1081 ttttcaaata aaaaaggggc tgtgacaaaa aaatgtcaca acctctaaaa gggtctattg
     1141 aagtagaaat aacgagttgt ctttatttct taattgatcg atatttttgc ccatcctttg
     1201 acagcttgag caaaaataaa gattcctgca aaagcaatga aggcgctagt gtcaaaagaa
     1261 ggaagaaaga ccatcaagat tgttgcaatt atagtaggca atgaaattga atagatcaat
     1321 gtttttaaac aatcaagaaa agtagctttt gttagtcgaa agcgtgcata gagaaaagca
     1381 gcaatgttgg taaatagcaa agtgatcagc agattcagaa aactaggata aatagaaaat
     1441 ataaatgtca ggacttttat ccaaagtggt atagatgctt cacttaaaaa agaacggagc
     1501 tgcttacctg ttaagttttt taaagattca ttggtgtagg gaagttctaa ttggttattg
     1561 ttcaacaaag cagaagtcgt gcctgtatta ggaagagcta tgataagttt gttttttaac
     1621 atcccgacac taacaaaatt ccccatcaaa tcagtagaga tgtcctgttc tgttcgtttt
     1681 ccctctggat caaatgtgaa gataatggag tttgtttggt aaatgaatcc ttctttttct
     1741 tcggtttgaa gctgcccgtt ttggattgta aaatcaggaa tgcgagtagc aatcttttgc
     1801 ccatccaatt gaatgttgtt taagacttga aaaacttgaa aagagattgg caaagccata
     1861 attatactca aaactaaaag atagacaatg gctttccaaa atgggacatt tctcgactcc
     1921 tttaggtctt tgaatcgtat aaaggaactg ataattaatt gttttgttgt cataagtact
     1981 cctcatctag tagtgtcatc acttgcaatt ctagcgaagt atcaagtgaa atacaagtgc
     2041 tttaaggaaa cagctgaatg attggtgaaa tatcaaaaaa atgttattct tgtctaaaga
     2101 ctatccaata taaataaaat ggaggaagga atagtgccta cacagccaca gagatcatca
     2161 aaaaaactat ttggagtagt ggttttgaat gcggtgatca ctttatcaga atttattgga
     2221 gggattatgt cagggagttt gtctcttgtt tcagatgctt tccataacct tagtgataca
     2281 ttggcaatta ttttttctta cggggcacaa aaaatggccc gaaaagaagc aaataaaaaa
     2341 cgtacgtatg gctaccagcg tttagaaata ttgagtgctt tcatcaactc attcatattg
     2401 atcatattat ccttgttttt aaccgttgaa gcattcaagc ggttcacttc accagaaaag
     2461 ataaatagtc atttgatgct aacagtagca gttattggat tgctcgcgaa tttgttctca
     2521 gtattattat tacgacaaga agcagatgaa agtttgaata taaaatctag ttatttgcat
     2581 ttgttaagtg atacactgtc ttcggtaagt gtgattatcg gagcaatttt gatccgtttt
     2641 ttcgatatct actggatcga tccagttatt acactgatca tttcgatata tatattgata
     2701 gaagcgataa tggtgatcaa aaaagctgcc gctattttga tacaaagtgc acctgctatc
     2761 gactatgaaa aaatggaaca agaaattgaa gcaatcgatg gggtaaagga tgttcatcat
     2821 gtccatattt ggcagtatag cgaaaagata attattttcg acggacatat tgattttgaa
     2881 gatcagctac taagcgagat tgaaaagata tatcctcgta taatttcttt attaaaatta
     2941 aaatatggta ttacacatgt gacgatccaa gcagagacaa aggcaaagga tcaaaaaaaa
     3001 ttaatttttt taaataaaga tgaaagttat tgaaatatag agtatgataa ataagaattt
     3061 ttaataaggt aggttggctc atgaagcagt atcgacagtt aaaaggatat ttagaagcaa
     3121 aaggatattg ggagatacta gtctatctct tttttggtgg tttggctacg attgtaaatt
     3181 ttgttagttt tgctctcgca cgccaatatt ttgatttaag tatggcctta tccaattcta
     3241 tttcgtggtt ttgttctgta ttgtttgctt ttgtaacgaa caaactttgg gtattccatt
     3301 caaaatcacc gaattttaca catgcactta ttgaatgcgg taagttcttc ttctaccgta
     3361 tcctttctta cggattggac atgggggcaa tggtattgtt gatcaatgtt atgaacagca
     3421 atgagtatgt ggcgaaaatc atcactcaaa ttattgttat ccttgcgaac tatattttca
     3481 gcaagttgtt tatttttaaa gaaactgagg tttttgaaga agaagtaggt caaagtgaaa
     3541 aagacgacta ggcataacaa ttgaagaatt tccttctctt tgttactctt tgtaatgtag
     3601 acattattaa gaaaacattg aggaggaatt tttttatgac ttacacatta ccagatctac
     3661 cttatgcata tgacgcattg gaaccttata ttgacgaaga aacgatgcat ctgcatcatg
     3721 ataagcatca caatacttat gtgacgaatt taaattcagc aattgagaaa tacccagaat
     3781 taggcgaaaa aacaatagaa gaattattat ctgatatgga cgctattcca acagatatca
     3841 agacagctgt acgtaacaat ggtggcggac atgctaacca ttcatttttc tgggaaatca
     3901 tggcaccaaa tgctggtggc gaacctacag gagaaataaa agaagcgatt aatgaagctt
     3961 ttggtgattt ttcttctttt aaagaagaat tcaaaaaagc agccgctgga cgatttggtt
     4021 ctggatgggc ttggcttgta atggaaaatg gaaaattagc tattacctct actgcaaatc
     4081 aagattctcc attgatggaa ggaaagacac caattctagg tttggacgtt tgggaacatg
     4141 cttattattt gaaatataaa aatgtccgac cagattatat tgcagcattc tggaatgtta
     4201 ttaattggga tgaagtaaac aaacgtttcg aagcagcaaa ataaccattt cctccgtcat
     4261 atcagtctta aaaataattt ggaaaataaa agagcgaaag cttgctagcg ttttctaaat
     4321 tgggtataat gttcttgcaa ggttacttgc aagaactttt ttggaggata tacatttatg
     4381 gaacacggaa cggttaaatg gttcaacaat gaaaaaggat ttgggtttat tacagtagac
     4441 ggcggagatg acgtatttgt tcatttctca gcaattcaag gagacggctt caagagccta
     4501 gaagaaggtc aagaagtaga attcacgatt gttgaaggtg cacgcggacc tcaagctgct
     4561 gaagtgacta aattataata atttgttgaa taaagacacg acttcttaga gagtcgtgtc
     4621 tttttgtcta tttatgaagt ttttagattt tttggctaag taaatgcatt tgttcacttg
     4681 acatgtccta actaattatc aagcaaggaa cattttcttc gttagtaatg gattttaaag
     4741 aaatttcagt ttttggatgt tgaataaaag accatttgtg aaaccactag tatacatact
     4801 cattaccatg tcaattctat tactttaaaa gaaaatcgtt ttactttgaa gaggagcata
     4861 tctatccatt aaaagatgat ggtaatgcaa tcactagttc gagtcatttt aagagccatg
     4921 cagtgagctg gaaataaaac gaatagaaga tgggtttaac aaaaggacca gtcataggaa
     4981 gaaattgtcg tgaaatcgaa tgataatctg aacggtaggc aaagactgtt aaaaagatgg
     5041 gaaaggtatg tgcgatcatt ttactgcacg attatttgga aaataccttg ttgttcgctt
     5101 tttctggaaa aaatacataa aaaaagataa aacgattgcg aactgcgtgt attcggtctt
     5161 tcgatctttt tcacggtatg gtatgatagt taagaatttt gagaaatttt
//
LOCUS       DACDAF010000122         5201 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.128, whole genome shotgun sequence.
ACCESSION   DACDAF010000122 DACDAF010000000
VERSION     DACDAF010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5201
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.128"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            2..667
                     /locus_tag="IVZ69_002553"
     CDS             2..667
                     /locus_tag="IVZ69_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184576.1"
                     /translation="MAYYLLSEPKQIAASNIFTAVMTLMCVMCFSIFSYLLVQFIRQN
                     LTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIKNFLTTIDQFINGYMYLFEVG
                     FILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVDFGKYEELIHTDIVHTSIHEV
                     TVKGIRSTLKDGQETKTIDQRKEVYNFYKVEASLRYGIGKLRLDGSNIQQNKPYVLGK
                     VVI"
     gene            711..980
                     /locus_tag="IVZ69_002554"
     CDS             711..980
                     /locus_tag="IVZ69_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184577.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            1212..1508
                     /locus_tag="IVZ69_002555"
     CDS             1212..1508
                     /locus_tag="IVZ69_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184578.1"
                     /translation="MNVKIRDLDPKFISEIDRRCVELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQEKFDQLLEKFSEIQSYNTKILEEYVSQNNRIIEILIEQNRGSEL"
     gene            1510..1932
                     /locus_tag="IVZ69_002556"
     CDS             1510..1932
                     /locus_tag="IVZ69_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184579.1"
                     /translation="MAKVIDKHIYFHQTHIDVLDETISTHAEVKNYSEAVRFLCMNYD
                     PEVEKKVNSNQAKLNGMSKEISILTEMVSEFADLHLKDTGILIGKNSTVYQEAKERVE
                     GKIKSNQTKKYSPQLKKPVNESVHARVDPFDPTKILKR"
     gene            1951..3543
                     /locus_tag="IVZ69_002557"
     CDS             1951..3543
                     /locus_tag="IVZ69_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184580.1"
                     /translation="MTQSPSVILTCQFTLPNKKSFSTYIDYITREQALEEKERRTPEE
                     EQELQRIKNALEEFYIPEGETFSESKTGKEFSETSNEAQSLMEHGINFDKLEEQDFTN
                     YLSYMTRHYALEQKKELTQSEQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSIASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWNYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            3564..3884
                     /locus_tag="IVZ69_002558"
                     /pseudo
     CDS             3564..3884
                     /locus_tag="IVZ69_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(4045..5186)
                     /locus_tag="IVZ69_002559"
     CDS             complement(join(4045..4958,4958..5186))
                     /locus_tag="IVZ69_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP8184581.1"
                     /translation="MAKAKKKFDEDFKKMILDLNQSGQSVEELAAQYGIATQTIYRWK
                     KLHTKNVATGMTEAEILAMKKEMARMQEENTIPKKGFNHIRSKVKMSDVFEFIQSNVH
                     DHDVKQMCTVLEAPKSSYYDWKKKKPSKRQSENKRLNRLISGIYFENKGIYGAPKIHK
                     ILVGRGETLSLKKVQILMRKLGLRSVTLKKYKPGKQAKVKSEGRKNLLNQDFTTTSIN
                     QKWVTDITYIHTLKDGWTYLSTIQDLHTKKVIGWKFGKQMTKELVIETLDNALLNQTP
                     SENLIIHSDLGSQYTSEAYEAKLNELNIRHSFSRKGCPYDNAGIESFHASLKKEEVYP
                     SKAYENFEAAYLALFQYIEGFYNRKRIHSSINYLTPNQMEELALQA"
BASE COUNT         1846 a          821 c         1042 g         1492 t
ORIGIN      
        1 ggtggcctat tacttgttaa gtgagccaaa acagatcgcg gcgtcaaata ttttcacggc
       61 agtaatgaca ttaatgtgtg tcatgtgctt ttctattttt agttacttac tcgtccaatt
      121 tatcaggcaa aatttaacaa tgagtaaact tttcaaaagt ttattggact tacttatctt
      181 aggcagtatg ttaacgactc taacagatcg gttcgaacaa tctgaaaaaa cggtagaggg
      241 gataaagaac ttcttaacga cgattgatca atttataaat ggatatatgt atttgtttga
      301 agtaggcttt attctcactt tgtttggttg tgtatttata aaactcatta aaagatcaat
      361 cgaaaaagaa atggttattg atctaattcc gacgctgagc ggctatgagt attacgttga
      421 ttttggaaag tatgaggagt tgatccatac ggatatcgtt cacacgagta tccatgaagt
      481 aaccgttaag ggcatcagat ctactttaaa agatggacag gagacgaaaa caatcgacca
      541 aagaaaagag gtctacaatt tttataaagt tgaagcaagt ctacgatatg gcattgggaa
      601 attgaggtta gatgggagta atattcaaca aaacaaacca tatgttttag gaaaagtggt
      661 gatttagaac ttcctatgaa agatgaataa ataaggagaa tcttttgaaa atgattcttc
      721 tttacagaat tgtgcttata gttggcacgg agttaaaaat cttaaagaag gagcagttat
      781 tcaaagtgaa agaacatcat aatcagttac tatgtattaa aacgggtacg atgaacattc
      841 aataccgaac agaatattta gaattaacga atcaaactga ttttttgtcg attcgagagc
      901 aacataagca agaaaaatta atggctactt atagccaatt gattgatgag tgggaacaat
      961 tcaaggaatc taaaacataa aattccattt aaacacctta ttttttaaag agcataagga
     1021 aacgtgaccc cacttttaaa aaaagtggtt ggataggctg tgcctatcac gtttctgaaa
     1081 aaaataaatg accccaaaat accaatatat aggatagtac aaggatagca aaggatagta
     1141 aaaggataga ggtaggatag cgaaaaggat aggatccttt tcactatcct atattatatt
     1201 ggaggatatt tatgaatgtt aaaattagag atttagatcc aaaattcatt tctgaaattg
     1261 atcgaagatg cgttgaacta agtaatcgta caggaaataa atggagtcgt aatgattatt
     1321 taaagctact cgttgaaaat gattttgatc gtcctttgat ggaatacaaa caagaaaagt
     1381 ttgaccagtt attagaaaag ttttcagaaa ttcaaagtta taacacaaag atattagaag
     1441 aatatgttag ccaaaataat cgtattatag aaatcttgat tgagcaaaat agaggaagtg
     1501 aactttgata tggcaaaggt tatagacaaa cacatttact ttcaccaaac acatatcgat
     1561 gtattggatg aaactatttc tactcatgca gaggttaaaa actatagtga agctgttcgc
     1621 tttttatgta tgaactatga tccagaagtg gagaaaaaag taaattccaa tcaagcaaag
     1681 ttgaatggaa tgagtaaaga aatttctatt ttaaccgaaa tggtttcaga atttgcggat
     1741 cttcatttga aagatacagg aatattaatt ggtaaaaatt caactgttta tcaagaagca
     1801 aaagaacgag tggaaggaaa aattaaatcc aatcaaacaa aaaaatattc ccctcagttg
     1861 aagaaacctg tgaatgaatc tgttcatgcc agagtagatc catttgatcc aacgaagatt
     1921 ctaaaaagat aaaaatgaag gaggataata atgactcaat cgccttcagt tattctcact
     1981 tgtcaattta ctttgccgaa taaaaagtca ttttctactt atattgacta tattacaagg
     2041 gaacaggctc ttgaagaaaa ggaacgacgt acgcccgaag aagaacagga acttcaacga
     2101 atcaagaatg ctttagagga gttttatatt cctgaaggag aaactttttc ggagagtaag
     2161 acgggtaaag aattcagtga aacgtcgaat gaagctcaat cgttgatgga acatggaatc
     2221 aattttgaca agttagagga acaagatttt accaattatc tttcttatat gacacgtcac
     2281 tatgcgttag aacaaaagaa agaactgacg caaagtgaac aaaaagaata ccaacgcttg
     2341 aaccaagcaa tgaaaaaata tcaaacagaa ccccataaaa aagcttcagg aaatcttcct
     2401 ggagtttttt ctatagcttc agacgaagtg aaaggaagtg atctgaagga gattaagcaa
     2461 atcttccaaa gaggacaaca aaaaggctca atcatttatc aagatgttgt ttctcatgat
     2521 aattcgtatc ttgaaaaaat aggattgtac gatcccaaaa cagatacttt agatgaagaa
     2581 gggttaaaag cagctggaag aaaaatgatg gagacattat tcgagaaaga acaattgaat
     2641 gaaacaggtt actggatggc aacgattcac cgtaacacta aacatatcca tattcatttt
     2701 gcagttgttg aaaaagaaaa tacgcgtaaa ccttacacgg aggttgaaaa tggtgtgagt
     2761 tatatcgtac cgaaaggtaa gagaagacaa gcaacattag acgcaatgaa gaccaattat
     2821 gtacatgagt tagaacgttt ttcttatgaa aaggatcgaa tgattggtat ggagaaacga
     2881 aatttattga cgcggaaaag tgatttgcgt aacaccttaa caaaagtggt aaaagagcca
     2941 gcgcgttacg atcgacacgc gatgaactta ttaaatgaag tatataaaac cctacctgac
     3001 aaacgttcgg aatggaatta cggggatgaa aaacgaacca aactttcacc atacacaaga
     3061 gagaaactcg atgagttaac caaatatgtt ttaacaaaag aacctgaata tcaagaatat
     3121 atacagattt caaaagcatt gaaagaagaa gcaaaaagtc tttatgggga aagcaagaga
     3181 gaatcaaagg atgcagagaa aaatgctctc tttgatttaa aaaagcgcac aggaaatgcc
     3241 atcctaacag agctgaagag acaggatagt caaataaaac cattaataga aagtgttgat
     3301 cagatgcaat ctatttacaa tgaacgatcc tttcgaacgc ttaaacaatt gccaacgaat
     3361 gaatacaaat atagttacga agaattcatg aagcgcagga aacaattcca acaaagagtt
     3421 gtcacgcagc ggagtttgcg tcaattaaat cgaacgatta atgcccatga agaaaaatac
     3481 cacgcaagta aagcatacga agagcaacaa cgaagaattc aaatggaaca agaaagacag
     3541 taaagacagt aggaggaata gcaatgaaac aatatttaga tcaatggaaa gttatagaag
     3601 gatcattaag agaagaacga atcgaacaac ttcctgattg tttagaaaaa gagcatttgt
     3661 tccagataag agaaatgttg agaaacgaac agtttgatcc aaatcaattt ttagtcgttg
     3721 agtacccagc tactggtgtg tattgttgta atcatgtgaa tggtgaaaaa tattttatca
     3781 ttcaagaata tgagggcaag ttagcacctt attatactac ttgggaaatg aatgaagagg
     3841 gaatcaataa ctttccatgt aaaagcattg gatttgagtc aatacctcgg acacgatttg
     3901 tgagaatttt ttcgagattc cagcgggtga gtatctcatc gtttcgacca gcggtcaaac
     3961 caaaaccgtt tgaccgctga tcgaagcgat gaagttgaaa ccctgtggaa atctcgccaa
     4021 aaaaatgtaa gtggtagcta ggaactaagc ttgcaatgcc aactcctcca tctgatttgg
     4081 tgttaaatag ttgatactac tatggattcg cttgcgattg taaaatcctt caatgtattg
     4141 aaataacgct aaataagcag cttcaaagtt ttcatacgct tttgatggat agacttcttc
     4201 ttttttgagt gaggcgtgaa acgattcgat accggcatta tcgtagggac agcccttacg
     4261 actgaaggag tgccgaatgt tcaattcatt cagctttgcc tcataggctt cgctagtgta
     4321 ctgagaaccc aaatctgagt ggatgatcaa gttctcggag ggtgtttggt ttaagagcgc
     4381 attgtcaagg gtttcgataa ccaattcttt cgtcatctgc ttgccaaact tccaaccgat
     4441 gactttcttt gtgtggaggt cttgaatagt ggagaggtag gtccagccat cttttagggt
     4501 atgaatatag gtaatatctg tcacccattt ttgattgatc gacgtagtgg taaaatcttg
     4561 gtttaacagg tttttacgtc cttcactttt aactttcgct tgtttgccag gcttgtactt
     4621 cttgagggtg actgaacgca agcctaattt tctcatcagt atttgtactt tctttaagga
     4681 caaggtctcg ccacggccaa caagaatctt atgaatttta ggcgcaccat agataccctt
     4741 gttttcaaag tagattcctg aaatcaagcg gtttaagcgt ttgttttctg attggcgctt
     4801 ggaaggtttc tttttcttcc agtcatagta gctggatttc ggtgcttcca aaacggtaca
     4861 catttgtttt acgtcatgat catgaacatt tgattgaata aattcgaaga catcactcat
     4921 ttttactttt gagcgaatat ggttaaagcc ttttttagga tagtgttttc ctcctgcatg
     4981 cgggccattt cctttttcat cgctaggatt tctgcctcag tcatgccggt tgctacattc
     5041 tttgtatgaa gcttcttcca acgataaatc gtttgtgtag cgataccata ttgcgctgcc
     5101 agttcttcga ccgattggcc agactggttt aaatctaaga tcatcttctt aaagtcttca
     5161 tcaaattttt tcttggcttt tgccatcgtg gacacgtcct t
//
LOCUS       DACDAF010000123         5192 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.129, whole genome shotgun sequence.
ACCESSION   DACDAF010000123 DACDAF010000000
VERSION     DACDAF010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5192)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5192)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5192
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.129"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            137..748
                     /locus_tag="IVZ69_002560"
     CDS             137..748
                     /locus_tag="IVZ69_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HAP8184582.1"
                     /translation="MYFILPTLYSLLCVMAPCIIYMVFFCKKNTLKHNILILIFMLYC
                     WKVFELTGTGGLTDIFYRPDTGRKFSLVQGSVNLVPFSGLNISFILNIVMCVPLGFLL
                     PIIWKSYRKIVPVFLAGALFSLIIEVSQIITTRATDIDDLIANTFGAVIGFILWAVLS
                     RVVSLKDKSSTVDYLEPYIYILIGFTGKFLLYFPFWFAFEVLS"
     gene            821..1750
                     /locus_tag="IVZ69_002561"
     CDS             821..1750
                     /locus_tag="IVZ69_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HAP8184583.1"
                     /translation="MKRFLKWGLVLLASLIVILMCTAVVISYVNRPYARAVYDRIKRI
                     LDKDFYDHLYLGSSFEIINLDTMDIHSYMKKDQEELPASLSKLFTIDYALSVLSLDEQ
                     ITISPTALDMQKADSSTAHLQEGDILSVYDIICAMVLPSGNDAAYSLAIYTGGKLDPD
                     AKNDEERYQSFMKNLDRYLSEQGYKHTHFTDAAGYDSNATTSAEDLTKVAAKLLKNDK
                     FAEIVAKETYRAKSIKGNVYNWNTTNQFMQQDNRYFTEGVKGVKTGSFDGRYNLCVYY
                     TSSSDNHYLLVSFGSESDSRRYVDVQNLLHNLP"
     gene            1908..2645
                     /locus_tag="IVZ69_002562"
     CDS             1908..2645
                     /locus_tag="IVZ69_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008902106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HAP8184584.1"
                     /translation="MLISCGARLAPFDIRELRELMSEDELELDKIGDRKTALFVIISD
                     TDDTFNFVVSIMYSQLFNLLCDKADDVYGGRLPVHVRCLLDEFANIGLIPKFEKLIAT
                     IRSREISASIILQAQSQLKAIYKDHADTIVGNCDSTLFLGGKEKTTVKELSETLGKET
                     IDLYNTSETRSNQKSFGLNYQKTGKELMSQDEITVMDGGKCIYQLRGARPFLSDKFDI
                     TKHKNYKLLEDYDKKNLFDVEEYLKQR"
     gene            complement(2693..3871)
                     /locus_tag="IVZ69_002563"
     CDS             complement(2693..3871)
                     /locus_tag="IVZ69_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP8184585.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHHYTPQTMSNMTKSFTEEVTSFKERELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILIDLQERG
                     VKNVLLFITDGLKGMAGAVQRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKKAALEARGAFAEKWKTSYPKMVESILSNDYLLTFYDFPLAIRKTIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESLERFLVSIFDTYNQKFLNRSHKGFQQVTDTLASMFTE
                     "
     gene            3894..3977
                     /locus_tag="IVZ69_002564"
                     /pseudo
     CDS             3894..3977
                     /locus_tag="IVZ69_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337676.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            4098..4499
                     /locus_tag="IVZ69_002565"
     CDS             4098..4499
                     /locus_tag="IVZ69_002565"
                     /inference="COORDINATES: protein motif:HMM:NF013068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184586.1"
                     /translation="MSDKFSKKISSDIKEDFKAIFKTASIELAGERKQLIMDKYGEDK
                     KVATACKILDEGFEDAMQVMVLPENIRQRLRTTNVLERLNEEVRRRERVVRIFPNCDS
                     VIRIIGALLMEKDDEWTSAPRKYLEFDRNEI"
     gene            complement(4706..>5192)
                     /locus_tag="IVZ69_002566"
     CDS             complement(4706..>5192)
                     /locus_tag="IVZ69_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010744709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8184587.1"
                     /translation="LKEAIDQIKTAVLYPHNGLPILLMGVSGSGKTFLAEKIYEYAKE
                     QQVIESNAPFIAYNCAQYFNFSINKIVENLTILDAMKVLRLVQKAVKELEKLMGIEFS
                     NNQLFLLYMHCCSMIERILRKESVDEQADIKEYIQKEGHNYEISKYPAYKTKFESTVI
                     K"
BASE COUNT         1642 a          879 c         1003 g         1668 t
ORIGIN      
        1 cctctaggaa aaaattaact agcaccacgg gttatgatat aataaaatgt attataggca
       61 tttttttaca agaaatagaa gcttgaagtt tatatgaagt tataaaattt aatttatatt
      121 ggaaggagga aaataaatgt attttatact acctacactt tatagccttt tatgtgtaat
      181 ggcaccatgt attatttata tggtattttt ttgcaaaaaa aataccctga aacacaatat
      241 cctgattttg atttttatgc tgtactgttg gaaagttttt gaattgactg gtacaggtgg
      301 actaacagat attttttata gacctgatac aggtaggaaa ttttctctag tacagggcag
      361 tgttaatctt gtaccattca gtggactaaa cattagcttt atattaaata tagtaatgtg
      421 tgtgccctta ggattcttac taccaatcat atggaaaagt tataggaaaa tagttcctgt
      481 tttcttggct ggggctctat tttcactaat tattgaagtc tcacaaatta taactacaag
      541 agcaacagat attgatgatt taatagcaaa tacctttggt gcggttatag gctttatact
      601 gtgggctgtt ttaagtagag tggtgtcctt gaaggacaag tcatctacag tagattattt
      661 agaaccttat atttatatat tgattggttt taccggaaaa ttcttactgt attttccttt
      721 ctggtttgct tttgaagtat tatcctgata attccataga aaataatgag tttgagttga
      781 gaaagaatat tcttgtacac aactctggaa aggaggaagt atgaaaagat tcttaaaatg
      841 ggggcttgtt cttttagcgt ctttgattgt gattctaatg tgtacagcgg ttgttatttc
      901 ttatgtgaat cggccgtatg caagagctgt ttatgatagg attaaacgca ttcttgacaa
      961 agatttttat gaccatctat atctaggttc ttcatttgaa ataataaacc ttgatacaat
     1021 ggatattcat agctatatga aaaaagacca agaagaatta cccgcctcat tgagcaaatt
     1081 atttacgatt gattatgcgc ttagtgtcct aagtttagat gaacagatta caattagtcc
     1141 tactgcactt gacatgcaga aagctgactc atctactgca catcttcaag aaggagatat
     1201 tttatctgtt tatgacatta tctgtgctat ggtcttaccc tcaggaaatg atgcagctta
     1261 tagtttggca atttatacag gtggaaaact tgatcctgat gcaaagaatg atgaagaacg
     1321 ctatcaaagc ttcatgaaaa acttagatcg ttatctaagt gagcaaggct ataaacatac
     1381 tcattttact gacgctgctg gctatgactc caatgctaca acatcagcgg aagatttgac
     1441 aaaagtagct gcaaagctac taaagaatga taaatttgca gaaatagttg ccaaggaaac
     1501 ttatagagca aaatcaatta agggaaatgt ttataactgg aatactacga atcaatttat
     1561 gcaacaagat aatagatact ttactgaagg tgtaaaaggt gtaaaaactg gatcgtttga
     1621 tgggagatac aatctatgtg tgtattatac atctagttct gataaccact atttacttgt
     1681 aagttttggt tcagagagtg atagtaggcg ttatgtagat gttcaaaatc tattgcataa
     1741 tctgccttga aatttcgtgc ctttaagcgc gtatctaaag tttctttgaa aagtttgaga
     1801 atgaagaaag tgagcagtcg aaaaacggtt gctcactttt ttgccctaaa atcgaaaaaa
     1861 tataaaaaag tcctttacaa cacgtctcag gaaaaactgc taagtcaatt ctaatatctt
     1921 gtggagcaag acttgcacct tttgatataa gagagcttag agaactaatg agcgaagatg
     1981 aactagaact cgataaaatt ggagatagaa aaactgcctt gtttgtaata atatcagata
     2041 cagatgatac atttaatttt gtagtttcaa taatgtattc tcaattattt aatctactat
     2101 gtgataaggc agatgatgtg tatggtggaa gacttccagt tcatgttagg tgtctacttg
     2161 atgagtttgc aaatatcggt ttgattccta aatttgaaaa actaatagcg acaattcgtt
     2221 caagagaaat atcggcaagt ataatactgc aagcacaatc tcaattaaaa gcaatttata
     2281 aagaccatgc agatacaata gttggtaact gtgactctac actttttcta ggaggaaaag
     2341 aaaaaacaac agtaaaagaa ttatcagaaa ccttaggaaa agaaaccata gacctatata
     2401 acacatcaga aacaagatca aatcaaaaat cttttggtct aaattatcaa aagactggca
     2461 aggaacttat gagtcaagat gaaataactg taatggatgg tggtaagtgt atttaccagc
     2521 taagaggagc aagacctttt ctatctgata aatttgatat tacaaagcat aagaattaca
     2581 aattgttgga agattatgat aagaaaaact tgtttgatgt agaagagtat ttaaaacaaa
     2641 gatagcgtaa aatattttgt gtaaataact cgtccttctg caaaataatg ggttactcag
     2701 taaacattga agctaatgta tccgtcactt gttggaagcc tttatggctt ctatttaaga
     2761 atttttgatt gtatgtatca aagatggata ctaggaaacg ctctagtgat tcttcatttt
     2821 gaaactgctc ttttctgtgg ctgtatttct tgatttgctt attaaaggat tcaatcaagt
     2881 tcgtagagta aatagtcttg cgtatggcta atggaaaatc atagaaagtg agcaggtaat
     2941 cgttcgaaag gatcgattcc accatttttg gataactggt tttccatttt tccgcaaaag
     3001 caccacgtgc ttccaatgcc gcctttttag atgacgcttg atacaccatt ttaaaatcat
     3061 cacagacttc cttacgatca tcgacacgca ctttgtgact gatattacgg gaaacgtgca
     3121 cacagcaatg ttgaaaacgg gctttggggt agaaccgctg cacggcccct gccatcccct
     3181 ttaagccatc cgtgatgaaa aggaggacgt ttttcacgcc acgttcctgg aggtctatta
     3241 aaatctcttc ccaaatcgtg atagattcag ttggtgcaat cgcatagctc aacacttcct
     3301 ttgaaccgtc cgggcgaatg ccaactgcga tatgaatggc ttccttggcg acggttttcc
     3361 gctttaaagg gatataggtt gcgtccatat aaatagcggc ataacggtca tgaagctcac
     3421 gttccttaaa tgaagtgact tcttccgtaa atgatttagt catattggac atggtttggg
     3481 gcgtgtagtg atgcccatac attttctcaa tcaagtctgc gatttccgac atggtaatac
     3541 cttttcggaa gaggtgaatg acggtctcct ctaaggtatc attcgtccgt ctataagcag
     3601 gaacagtctg ttgcttgaac tcgccgttgc ggtcgcgcgg aatctggaga tgaagttccc
     3661 cgtactcggt cttgaccgta cggtcatagg agccgttacg agaattaccc gtgttaaaac
     3721 caatgcgatc gtacttttcg taatcgagga aagccgttaa ctccgttttg agaagcgtat
     3781 tgacagcttt ttccaaatgg acacggaata attcattcaa atcgccttta ttcgctagag
     3841 tctttagaat ttctgtagta aaatcgttca tatggaagtc ctcttttctg tgaatgtgtt
     3901 gtggtaactc tattctactg aagggacttc cttttttcta tttacacaaa atattttaca
     3961 ctctcggatt gaaagaacgc ggtctttcag gagtaaagat ggtcatctcg gatgcgcata
     4021 tagggctcac aaaagctgtg aaagaatacc ttctttgtgc gagctagcag agatgccaag
     4081 cacatctcct tcgcaacatt tccgacaaat tctccaagaa aatctcaagc gatatcaaag
     4141 aagactttaa agccatcttc aaaacggcaa gcatcgagct ggctggagaa cgtaaacaac
     4201 ttattatgga taaatatggg gaagacaaga aagtcgcaac tgcctgtaaa atattggatg
     4261 agggcttcga agatgccatg caagtaatgg ttttaccaga aaatatccgt caacgattga
     4321 gaacaacgaa tgttcttgaa agactaaatg aagaagtacg ccgtcgtgaa cgtgttgtcc
     4381 gaattttccc aaattgtgat tctgttattc gtatcatcgg tgctttattg atggaaaagg
     4441 atgacgaatg gacttctgca cctagaaaat atcttgaatt tgatcgtaac gagatttagc
     4501 acattaagcc gccaatagta taatatactg gtgagaagta tcaagagacg cttcgctttt
     4561 tgctcttgac acttcttacc agcatattgg accgtagcta ggctcaacaa ggcaaaacat
     4621 cgtactttga gatttccttt ttacacaaga ttttggactt gacacagccc ctatggttct
     4681 taccttgttt atgcttattt aaatcttact ttattacagt actttcaaac ttcgttttgt
     4741 aagccgggta ttttgatatt tcataattat gtccctcttt ttgaatatat tctttgatat
     4801 ctgcttgttc atctacactt tctttgcgta aaatacgttc gatcattgag cagcagtgca
     4861 tgtaaagcaa gaacaattga ttgtttgaaa attcgatccc cattagtttt tcgagttctt
     4921 tgacggcctt ttgtaccaat ctcaaaacct tcattgcatc aaggatcgtt aaattttcta
     4981 cgatcttgtt aatcgagaaa ttaaagtatt gagcacaatt ataggcgata aatggagcat
     5041 ttgattctat cacctgttgt tccttggcgt attcataaat tttttctgcc aaaaaggttt
     5101 ttcctgaacc gcttacaccc atcaataaaa tcggtaatcc gttatgagga tacaagacag
     5161 ccgtcttgat ttgatcgatc gcttccttta aa
//
LOCUS       DACDAF010000124         5103 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.130, whole genome shotgun sequence.
ACCESSION   DACDAF010000124 DACDAF010000000
VERSION     DACDAF010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5103
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.130"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            229..1503
                     /locus_tag="IVZ69_002567"
     CDS             229..1503
                     /locus_tag="IVZ69_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8184588.1"
                     /translation="MSKVNVFKNQSYLQSSATLLLFFASWGVWWSFFQLWLTSESNGL
                     GLSGSAVGTVFSANSLVTLILMFIYGTLQDKLYIKRNLLIFASVLATLVGPFFIWIYG
                     PLLDNNFNLGIIMGALFLSAGYLASVGVFEAVSERFSRLFGFEYGQARAWGSFGYALV
                     ALLAGFLFVKNPHLNFWAGSFFGSLLLLNLLFWNPKVEREANQNFNQEQAESNSIPSL
                     KEMFDLMKLPQLWTIIIFIVFTWTFYTVFDQQMFPGFYTGLFSTSANGEKIYGTLNAI
                     QVFCEALMMGIVPIIMRKLGVRNTLLLGVTIMCVRIGLCGFASTPLSVSCIKMLHALE
                     VPLFTLPMFRYFTLHFDTKLSATLYMIGFQIAAQIGQVILSTPLGILRDNVGYQPTFK
                     IISLIVLLAGIYAFFILKQDDRDVQGDPFIRG"
     gene            1557..2984
                     /locus_tag="IVZ69_002568"
     CDS             1557..2984
                     /locus_tag="IVZ69_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HAP8184589.1"
                     /translation="MTKRAIELTNTRYRLGYHVSAPSGWINDPNGFCYFDGYYHVFYQ
                     HHPYSAEWGPMHWAHARSKDLVHWESLPLALTPGDQEDEGGCFSGSAIEKNGVLYLFY
                     TGHHYYGDNDPDHFWQNQNMAYSTDGIHFTKYEKNPVIAKAPEDNTHHFRDPKVWKHD
                     EKYYMVLGSQEKDGLGRAIVYQSLDLLNWDYIGPISKAKEVLTEGFMWECPDFFELNG
                     KSILLLSPQGIEANGKDYLNLYETGYFIGDYDYETAKFIRGNFYELDKGHDFYATQTT
                     LSPDGRRIVMAWMDMWESPMPEKVDGWAGALTLPRELELIGDRLYMKPVRELEQLRVG
                     SGVETTVNLAGEIIIAQDASFKEALIDVLLTKSKNQEVKFSLKTKDEELINIFYSKDK
                     NECTLTRNGKNDPRYGTIQMCDRLSLRVFIDKSSAEIFINDGELVFTERYYTENQPSM
                     HLSVSEEAFVSSTIYHLKKDAISYE"
     gene            2997..3869
                     /locus_tag="IVZ69_002569"
     CDS             2997..3869
                     /locus_tag="IVZ69_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016185828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HAP8184590.1"
                     /translation="MLIGSIEAGGTKFVCAVGDEDYRVQDQIICPTTTPRETLKKTVD
                     YFKQFDINALGIASFGPIEIRKNSPKSGYITSTPKVGWRNVNVLGYLQDELNVPMSWT
                     TDVNGSAYGEYIMSTLSNEKINSLVYYTVGTGVGGGAVVDGKLLGSFGHSEMGHTFVK
                     RHPDDIDFKGICPYHGDCLEGLVAGPTFEARFGKKGEDVSLTDPIWDVMAYYLAQAVI
                     QTTLIIRPDKIVFGGSVVNEKLLEKIRVNVNKLLDDYVEIPPLSKYITRPLIKNNGSA
                     TLGNFALGLNQLQE"
     gene            3964..4959
                     /locus_tag="IVZ69_002570"
     CDS             3964..4959
                     /locus_tag="IVZ69_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family transcriptional regulator"
                     /protein_id="HAP8184591.1"
                     /translation="MRPKLEDVAKRANVSKTTVSRVLNNRGYLSQKTIDNVYKAIEEL
                     NYQPNVVARQLFQKKTNIVGLLFPTVANPFFSELVEALEKKLYEIGYKVLIGNSMNNK
                     EKETNYLNQLLSDQVDGLIVGTHNQGIQEYKYQNLPIVAIDRVMNEDIPVVESDNYNG
                     GKLATKLLIAQGAKNIIHTNGPIDLQTPANRRRLAYEDTMKAYQLIPRTVTLDFNISY
                     VKKKQIFFQMFEDYPKIDGIFASNDIDAALILQVAKEKGLNVPADLLVVGYDGTLMTR
                     SILPDLTTVIQPINDIADTAVAILMKRINKEETKKEYILPVTLWMGKTSVKKKNN"
BASE COUNT         1760 a          704 c          995 g         1644 t
ORIGIN      
        1 tcgcttaatt atacaaacgg cgttataaaa aatagtgcca ttaaaaaaga aaagcgacac
       61 accaataaaa gtcatatcct gtgacattat atggcattat ccaaatagaa taaccggttg
      121 acatgtaagc ggatttcttt tataatttta ggagtacaag tccttttcta aaaatgttaa
      181 ccggttatca tgaaagggga tacaaatata tcgttggagg ataaaaatat gtcaaaagtt
      241 aacgtattta aaaatcaatc ttatttacaa agttcagcta cattattact attttttgct
      301 tcttggggtg tttggtggtc attttttcaa ctttggctaa catctgaatc aaatggttta
      361 gggttatctg gcagtgctgt aggaacagta ttctcggcaa attcgttagt taccttaatt
      421 ttgatgttta tttatggaac attacaagat aaattgtata ttaaacgaaa tttattaatt
      481 tttgcttctg tattagcgac acttgttgga ccatttttta tatggatata tgggccattg
      541 ctagataaca attttaattt aggcattatt atgggagcgc tatttttgtc agctggatat
      601 ttagcttctg taggagtttt tgaagctgtg tcagaaaggt ttagtcgttt atttggcttt
      661 gaatatggac aagcaagggc gtggggatca tttggttatg ccttggtagc gcttttggca
      721 ggatttttat ttgtaaaaaa tcctcattta aacttttggg cgggatcttt ctttggttct
      781 ttactattgt taaatttatt attttggaac cctaaagttg aacgggaagc aaatcaaaat
      841 tttaatcaag aacaagctga atcaaatagt attccttctt taaaagaaat gtttgatcta
      901 atgaaactgc ctcaattatg gacgataatc atctttattg tttttacatg gacattttat
      961 acggtattcg atcaacaaat gtttccggga ttttatactg gtttgttttc aacatcagct
     1021 aatggtgaaa aaatatatgg gacattgaat gctattcaag tattttgtga agcgttaatg
     1081 atgggaattg ttccaatcat tatgagaaaa ttaggggttc gaaatacttt gttattaggt
     1141 gtaaccatta tgtgtgtacg aattggattg tgcgggtttg cctcgacacc attatctgtt
     1201 tcatgcataa aaatgttgca tgctttagaa gtaccattat ttacattacc aatgtttcgc
     1261 tattttacac ttcattttga tacaaagcta tcagcaaccc tctatatgat aggatttcag
     1321 atagctgctc aaattgggca agtgatttta tcaacaccat tgggaatatt aagagacaac
     1381 gttggctatc aaccaacatt taaaattatt tctcttattg tattactagc aggcatatat
     1441 gcattcttta ttcttaaaca agatgataga gatgttcaag gggatccatt tattcgagga
     1501 taatggaaac caacagaata aaaaacaatt ttatctagaa agtgagcgaa tatattatga
     1561 caaaaagagc tatagaatta acaaatacac gttatcgttt gggatatcat gtgtctgcac
     1621 catcaggatg gattaatgat ccaaatggat tttgctattt tgatgggtat tatcatgtgt
     1681 tttatcaaca tcatccatat agtgctgaat ggggaccaat gcactgggca catgctagaa
     1741 gtaaggattt agttcattgg gaatctttac cacttgcttt gactcctgga gatcaagaag
     1801 atgaaggtgg ttgtttttca ggaagcgcta ttgaaaaaaa tggtgtgttg tatctgttct
     1861 atacaggaca tcactattat ggagacaatg atccagatca tttttggcaa aatcaaaaca
     1921 tggcgtatag tacggatggc attcacttta ctaaatatga aaaaaatcct gtaatagcaa
     1981 aagcaccaga agataacaca catcatttca gagatccaaa agtatggaaa cacgatgaaa
     2041 aatattacat ggttttgggt agtcaagaaa aagatggatt aggtcgtgct attgtttatc
     2101 agtcgttaga tttattaaat tgggattaca ttggaccaat ttctaaagcg aaggaagtac
     2161 ttacagaagg atttatgtgg gaatgcccag acttttttga attaaatgga aaatctattc
     2221 ttttattatc ccctcaggga attgaagcaa atggaaaaga ttatttaaat ctatatgaaa
     2281 caggctactt tatcggtgat tatgattatg agacagcaaa attcattaga ggaaattttt
     2341 atgaattaga taagggacac gatttctatg caacacaaac aactttatct ccagatggta
     2401 gacgtattgt tatggcctgg atggatatgt gggaaagccc tatgcctgaa aaagtagacg
     2461 gatgggcagg agcattaacg cttcctcgag aattagagtt aattggagat cgtttgtata
     2521 tgaaacctgt gagagaatta gaacaacttc gagttggcag cggcgttgaa acgacagtta
     2581 atttggcagg agaaataata atcgctcaag atgcttcatt caaagaagct ctaattgatg
     2641 tactattgac taaatcaaaa aatcaagaag tcaaattttc attaaaaaca aaagatgaag
     2701 agttaatcaa tattttttat tctaaggata aaaatgaatg taccttaact cgtaacggca
     2761 aaaatgatcc aaggtatgga accattcaga tgtgtgatag attatcactt cgagtgttta
     2821 tcgataaaag ttcggcagag atttttatta atgatggcga gcttgttttt acagagcgtt
     2881 attatacaga aaatcaacca agtatgcatt tgagtgttag tgaagaagct tttgtctcga
     2941 gtacaattta tcatctaaaa aaagatgcaa tttcttacga gtaaggaggt tttatgatgt
     3001 taattggtag catagaagca ggtgggacta aatttgtatg tgccgtggga gacgaggatt
     3061 accgagtaca agaccaaata atttgtccaa cgaccacccc cagggaaaca ttgaaaaaaa
     3121 ctgttgacta ttttaaacag tttgatataa atgcattagg tattgcatca tttggtccaa
     3181 tagaaattcg aaaaaattca ccaaaatcag gatatattac gtctacacca aaggtgggat
     3241 ggcgaaatgt taatgtgtta ggttatttac aagatgagct gaatgttcca atgtcttgga
     3301 caacggatgt gaacggatca gcttatggag agtacatcat gtccacttta tcgaatgaaa
     3361 aaataaattc attagtttat tacaccgttg gtactggcgt tggtggtgga gctgttgttg
     3421 acggaaaact attaggatcg tttggtcatt cagaaatggg ccatacgttt gtaaaacgcc
     3481 atcctgatga tattgatttt aaaggaattt gtccttatca tggtgattgt ttagaaggct
     3541 tagttgcggg accaacgttt gaagcacgtt ttggaaaaaa gggtgaagac gtttctttaa
     3601 cggatcctat ttgggatgta atggcctatt atctagcaca agctgtgatt caaacaacat
     3661 tgattatacg accggataaa atagtatttg gtggaagcgt agtaaatgaa aaattgttag
     3721 aaaaaattcg tgttaatgtt aataaattat tggatgatta cgtggaaata ccaccgttaa
     3781 gtaaatatat tacgcgtcct ttaattaaaa ataatggatc ggcaacacta ggaaactttg
     3841 ctttgggctt gaatcaatta caagaataaa acatagaaaa aatatcgatt atcaggtata
     3901 gtagttctat agagttcttt ttttcgatag ttaattattg cattatttag gagagacaag
     3961 agaatgcgcc caaaattaga agatgttgcc aaaagagcaa atgtatcaaa aacaactgtt
     4021 tcacgtgtat taaacaatcg tggctattta agtcaaaaaa cgattgataa tgtttataag
     4081 gctatagaag aactcaatta tcaaccgaac gttgtagcgc gtcaattatt tcaaaagaaa
     4141 actaacattg tcgggttact atttcctaca gtagccaatc ctttttttag tgaactcgtt
     4201 gaggcattgg aaaaaaagtt atatgaaatt ggttataagg tattaatagg caattcgatg
     4261 aataataaag aaaaggaaac aaattattta aatcagttat tgtctgatca agtagatggt
     4321 ttaattgttg gtacacataa ccaaggaatt caggaatata aatatcagaa tttaccgatt
     4381 gttgcaattg atcgagtgat gaatgaagat attccagttg ttgaatccga taactacaat
     4441 ggtggaaaac ttgcaaccaa gttattaatt gcacaaggtg caaaaaatat tattcataca
     4501 aacggtccaa ttgacttaca gactccggct aatcgtcgga gactagccta tgaagatact
     4561 atgaaagcat atcagttaat tccacgaact gtgacattag atttcaatat ttcttatgta
     4621 aagaaaaaac agattttttt ccaaatgttt gaggattatc ctaaaataga tggtattttt
     4681 gcttcaaatg acatcgatgc ggccctaata ttacaagtag caaaagaaaa ggggttaaat
     4741 gtaccagctg atttattagt agtcggatat gatggtactt taatgactcg gagtatatta
     4801 ccagatctga caacagtaat acaaccaatt aatgatatag cagacacagc tgttgctatt
     4861 ttgatgaaac gaataaataa agaagaaaca aaaaaggaat atattttacc tgtcacatta
     4921 tggatgggga agacatcagt aaagaaaaag aacaattaaa tttataaaga ctatcaatga
     4981 taatttcatt attaattcgt gatataaaaa attgttaaat ctcttataat agactatgat
     5041 acaaaatcat gcttttaatc tgtgtagatg ttgccaaata tttgaaagac atagaacttg
     5101 tca
//
LOCUS       DACDAF010000125         5007 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.131, whole genome shotgun sequence.
ACCESSION   DACDAF010000125 DACDAF010000000
VERSION     DACDAF010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5007
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.131"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..182)
                     /locus_tag="IVZ69_002571"
     CDS             complement(<1..182)
                     /locus_tag="IVZ69_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP8184592.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
     gene            517..951
                     /locus_tag="IVZ69_002572"
     CDS             517..951
                     /locus_tag="IVZ69_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HAP8184593.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            974..1294
                     /locus_tag="IVZ69_002573"
     CDS             974..1294
                     /locus_tag="IVZ69_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184594.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1435..1626
                     /locus_tag="IVZ69_002574"
     CDS             1435..1626
                     /locus_tag="IVZ69_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184595.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(1697..1954)
                     /locus_tag="IVZ69_002575"
     CDS             complement(1697..1954)
                     /locus_tag="IVZ69_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HAP8184596.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2112..2375
                     /locus_tag="IVZ69_002576"
     CDS             2112..2375
                     /locus_tag="IVZ69_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184597.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2399..2587
                     /locus_tag="IVZ69_002577"
     CDS             2399..2587
                     /locus_tag="IVZ69_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184598.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(2670..2855)
                     /locus_tag="IVZ69_002578"
     CDS             complement(2670..2855)
                     /locus_tag="IVZ69_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184599.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3070..3441
                     /locus_tag="IVZ69_002579"
     CDS             3070..3441
                     /locus_tag="IVZ69_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HAP8184600.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(3591..3663)
                     /locus_tag="IVZ69_002580"
     tRNA            complement(3591..3663)
                     /locus_tag="IVZ69_002580"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3628..3630),aa:Gln,seq:ctg)
     gene            complement(3709..4137)
                     /locus_tag="IVZ69_002581"
     CDS             complement(3709..4137)
                     /locus_tag="IVZ69_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184601.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4197..4955)
                     /locus_tag="IVZ69_002582"
     CDS             complement(4197..4955)
                     /locus_tag="IVZ69_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C39"
                     /protein_id="HAP8184602.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
BASE COUNT         1744 a          784 c          978 g         1501 t
ORIGIN      
        1 gaatttgatt ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc
       61 gttgatagag tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc
      121 atgaagaatg cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc
      181 atgaaaaatc tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt
      241 taacacgtga aaatatttca taggtaaaag aagcatgaca atttatgaca aatccacgtt
      301 ttttgtaaca gaatgatgtt cgctcgatgt gaaaaatgat gaggaatttc acataatgca
      361 gaaataatgg gattagaaca ggtgttctga tgagaaaaga aatgtataaa taacttgaaa
      421 gaaattgctt ttgttcatca ttttatttac atattgcgta tattttttgt atttttgctt
      481 gagatgttac aataaaagaa aaaggaggcg gttccaatga gtaaaagata ccagaacatc
      541 atggtagcag ttgacggatc aagacaatcg atcaaagcgt tcgctgaagc ccttgactta
      601 gcaaaggaca atgaagccca cttatttatc gtgtcaatca tcaacaaagt tgagctgacc
      661 catagtgcct atgccttttc aaaaatctat gcagatgaaa aacaaagaac agaagtagcc
      721 atgctgaaaa aaatcaatga tgccaaagag tacggcattg ctgagatcca cgcaatagtt
      781 gaaactggag atccaagaaa tttgattgcc aatgtcatcc ctggacaaga aaatattgat
      841 ttgatcgtta tgggagcgac aggaaaaggt gctatacaac aagcattagt tggatcgacc
      901 gcttcttatg tcgtatcaca tgccccttgc agtgtgttgg tcgtgaagta atgagataag
      961 ggaggaatag aaaatggttc gtcctcaaga agtccgtgcg ccaaaagaaa aaatagaaat
     1021 tttagcaatt attgaagacg gcacacaaac aaagaaggga tactcgatcg ctttagtaaa
     1081 gtggaaagga aaaaaaggtg ttgctctgag atgggatgga gataaccaac aagataaagg
     1141 attccctgtc acagctaacg gttatcatcc agcgtggttt gttctgcctg ataaatttat
     1201 ggaattatac agctatgatt atgcaagagc cgcagcatca atcaaagcat tagataaatt
     1261 aacagaagag cagaatgaaa tggaggaaaa ataaaaaaga cgaaccaatc agcctttaga
     1321 aaactgatta gttcgaggag taaaaatgaa aaaaggttat ttgggatgaa actagaataa
     1381 tgcgtataac ttaaataaaa cttaaagcaa taaaatggca agagggtgag gcaaatggaa
     1441 gcaggaaaag tattacagga agtaaaagca ctatgtgcag ataaaaaata tgaagaagcg
     1501 aaaagcctga tcgaaaagaa caaagaaaat ttggaagaaa agtacccgat cgcacaagaa
     1561 tttatagaat taaaacaagg aacgatcctt caccgattca aacatttttt tggtataaca
     1621 gaatagaaaa aacgattaaa gatcggcaga aatttgctgc atctttaatc gttttctttt
     1681 taaacatgcg agggattcaa ttctgattct tatataaaaa atagatccaa ataataagaa
     1741 aaattactga aagcgtcaat tcgatgatgt gtgttattaa tacagacgtt gtttcccaat
     1801 gcctaaaaga aaaaatttga taagtaaaat atacagcagg taaagaggcc agtaaaactg
     1861 aaaacttctt ttttgtccat tttatgtaat agaaaagaat gcttatcata ataaaaaaag
     1921 gaatataaaa aacaaattga ccgatcgcga tcatactatt gcctccgata aataaagtcc
     1981 atgatacaaa ataacacttt gtgcgaaatg gcgcaagcag ttttgtggat ttatccggta
     2041 aaatctgtat cgattttgaa attagaggag aaacttgcta taatcaaagt gaaagaagga
     2101 gtgggatttt catggatcat gtagtgttag aaatcgattt gcatttgatc aataatattc
     2161 gggtgattta ctatgttgta agtaacagtg tcgaacaacg tgtactgacg aataaaataa
     2221 atggtatttt agcaaagaaa gacgttcacc gattcaataa tggtgaagga agttattata
     2281 gtatcccagt agaaaaaatt atttatacga cagtcaaagt cagagaagat ctagatacca
     2341 aaaaagcata tgaacctatt tttacaactt attgattgac agcagatgga ggaaaaaaat
     2401 gaatccatat gaacaactta ttcaagattt gatcgatgga aaaatcgaaa agattgatgt
     2461 aaaaagagaa gaattaatgg cttttcgaga agcgtggctg aagttggaga atcgtaaata
     2521 tgtggtggga aaagcctcac tgaacggcaa tgtgacttat cattacgatc cgacacgttt
     2581 attttagtat gaagtattca gaaaagaacc aaaggaggac gatgcagcag cattgtcctc
     2641 ctttgatttt acaaaagtga aagttttact tatttgaata gatttttaaa tttgtttttg
     2701 acactgtcga tatttacatc ttttaaaaga ttttgggctt tctctttata aggtcctaat
     2761 tgttctttat gttcttcgat aaatcgtttt gcgccatcga aattgccgtt cttaatcatt
     2821 tccttgactt tttgaaataa ttcttcttga ttcattttga acacatcctt tgctatcaac
     2881 atgatttttt acatggacaa aacgagaaaa actgatttat ccacacgtca ataatatcaa
     2941 ataacgatca tttttactaa aaaaacactc gattctcgct tctaaagtag gagaaaaatc
     3001 tccaacttgg gacggatgga atttctttaa ctgacccata tactgaatat ataacaagga
     3061 ggtagaaaga tgaaagtgat taaatatttg attggactgg cggcgattag tggtattttg
     3121 ctatttggac tgaaatatta tactgaagga agttatggag aaatccctgg tatacttgat
     3181 cagctaaatc cattagttga aaaaggagag gtctatgtaa agacacaaaa accagaggaa
     3241 gtaaatgaat atggtacagc aaggtatgtg cagaaagctg ctgatgccaa tgggaaagaa
     3301 cgaacggttg aatttaatgg tctttctgtg ttaaaagaaa atcattattt gaaaattagc
     3361 aataaaggag cacacataga aacgtatgag gaagttccta gagaaaaagt tccggagaaa
     3421 gcattagcaa ttattgggta aatcagtttt tgtattaaga atacgcccga ttttattatt
     3481 cataatttaa ttatgtaaac taaatacaag tagtaaaaat aatacaataa tccccctgca
     3541 aaaagattgt tcttttacag ggggttcatt ttttcagcaa gcacatcaaa ttgggatggc
     3601 agggttcgaa cctacaattg cttgattcag agtcaagtgc cttaccagtt tggctacatc
     3661 ccatttattc aacaaaataa tcatagcact ttcctaaaaa aacgcaagtt atttttcttg
     3721 atcggatagt tgttgcttta ctcgtaaaag gcggcgtact agtttctttt ctaatccagc
     3781 aggaagggca atcagttctg ctactgacaa gacggtgtcc aataactgat attctttgac
     3841 aggttcattc ataatatgat agatgtttgc taaacgttca atatattcaa agcgagtata
     3901 ctctgttcga gcaattagaa atttcaataa atcggtggct ttctcgtact cttgatctgc
     3961 gtaataaaca agagattgac gatacaattt gatttccagt tcattgaggg tagcaggtct
     4021 gcgacgctcg ttccactcat taatagagac tttaccttga acatttccct tgcagtcacg
     4081 gacaaaaata atcggaattt catttggatc cattttttta tgtgtgaatt tttccattat
     4141 ctacgctccc ttcaaaggtt tggtatcttg agtataaggg atttttgttt gaattactag
     4201 cttttctcca aagttagcat ctgtccaccc attgcagtga aaatcgccga aaaatcgttg
     4261 atcggtactg ctcgattttt tacaccatag ggatcgttga cataaatatt ttctttgtca
     4321 tatccagtga ctacacaagc atgaacaaga ggagtgactc ttacttctcc attatttgtg
     4381 gtccaagtca taaaatcagt ttcatctggg acttcaaaat tgatagtcac agaagtccag
     4441 acaggatttc ctttagatag tgcttttttg atatcatcga gttgagcatc ggtttttgga
     4501 aaagtgtgat aatccgtttg gacgatttgc tgagcaaggg aggcaactgg gggaacatag
     4561 acgaccatag cccagtctcc gccactgata tcaccaacaa atccttcatt aggatcgcca
     4621 tgagtcccat ctgcattgaa aacagggacg taatccaatt gctcagctaa ctggttttta
     4681 gttgtttcat aaccataaaa agataaaagc atagaaagcg aagtgacttc acagccattt
     4741 tctaaagaag gagaatcaaa ctggctctct aatggaacat ctagtaaaac ttctgctttc
     4801 tcttttgtct ttttcgtttt ttgtgttgaa cttttttgtg cagtgttcat tgtatgttct
     4861 ggagaatgga tatgtaggta ataacttgta ccgcttaata aaagagcagc tgtgccccct
     4921 agaaacaata gttttttgaa cgtttttttc ttcatttgaa atctcccttt tcagctgttt
     4981 atctttccta ttataaatgt attttta
//
LOCUS       DACDAF010000126         4827 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.132, whole genome shotgun sequence.
ACCESSION   DACDAF010000126 DACDAF010000000
VERSION     DACDAF010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4827
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.132"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            59..174
                     /gene="rrf"
                     /locus_tag="IVZ69_002583"
     rRNA            59..174
                     /gene="rrf"
                     /locus_tag="IVZ69_002583"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(227..697)
                     /locus_tag="IVZ69_002584"
     CDS             complement(227..697)
                     /locus_tag="IVZ69_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HAP8184603.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(856..1314)
                     /locus_tag="IVZ69_002585"
     CDS             complement(856..1314)
                     /locus_tag="IVZ69_002585"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HAP8184604.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(1485..2630)
                     /locus_tag="IVZ69_002586"
     CDS             complement(1485..2630)
                     /locus_tag="IVZ69_002586"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HAP8184605.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(2643..3560)
                     /locus_tag="IVZ69_002587"
     CDS             complement(2643..3560)
                     /locus_tag="IVZ69_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HAP8184606.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3988..4551
                     /gene="efp"
                     /locus_tag="IVZ69_002588"
     CDS             3988..4551
                     /gene="efp"
                     /locus_tag="IVZ69_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HAP8184607.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
BASE COUNT         1513 a          885 c          921 g         1508 t
ORIGIN      
        1 tgacttcaaa tccagttttg agtgaacaaa atttactcaa taaaagataa caccacagtg
       61 tggtggcgat agcgagaagg atacacctgt aaccatgccg aacacagaag ttaagcttct
      121 tagcgccgat tgtagtgagg ggttgcccct tgtgagagta ggacgtcgcc acgcaaaggc
      181 aaaaagatga actagaaata gttcatcttt ttttattttt attaagttaa agaacggatt
      241 caattgcagc ggtcattttc aatggagaag tttgtggtgc aaatcgttcg attactttgc
      301 catttctatc aatcaaaaat ttagtaaaat tccattttat tgctttagtg acagtaccag
      361 gagcttcatt tttaagataa gtaaaaagag gatctgtatt ttctccattt acgtcaatca
      421 attgatgcat agggaaggta acgccataag tggttttaca agcttctgct gcttcagtcg
      481 ctgaatctag ctcttgttta aattgattgg aaggaaagcc taagataacc agaccttgtg
      541 tctgataagc ttggtaaagt tcttctaatt gtttaaattg aggtgctaga ccgcattttg
      601 ttgcagtgtt aacaatgatt atcggtttgc ctgcatattt tttcaatgaa tagacagtgc
      661 cgtcttctaa agtagtttca aaattataaa tagacataaa gttttctcct ttctatttta
      721 tataataaaa agagcgctaa actgaaaact agctatttgt tttcccgttt agaactcttt
      781 tcagacaata aatatttaat aaaatacgaa gataagatag ctatattgct tctcatcttt
      841 acgttctttt agaaactatg cttctacttc agaccattca tcgcgttttg ctaaaaattc
      901 acgagccaaa gcttgtgcac cttctagtgt atggctggca gcccagccac attgtgtttc
      961 attgcttgca ggtacttcag tagcttcaag aacatctttc attgttgctt caagaacatc
     1021 taaaatgtct tcgtagcttt catgattcaa tacagtcaag taaaagcctg tttggcatcc
     1081 cattggagac cagtctacga tgtaatctgc gtgattgcgg attagttcgg cagtcaagtg
     1141 ctcaagtgaa tgtagacttg gcatgtccat gtgttcttta tttggttgtt taaagcggac
     1201 gtcgtattta atgatgacat cgccatgcgc acccgttttt cgatcagcta cacgtacata
     1261 aggtgctttg acttttgtat ggtcaagatt aaaactttcg acattcattc tcatttgtaa
     1321 gactcctatc tgtttgttca ttcgttttga tgcttttcac taaagaatta tttagtgaaa
     1381 tttacaaaaa cgtctttcta cttgattcta acacttatcg tttccaaggt gtagcaatct
     1441 gaaatatttt ttagattttt ctgctaagtc gtttattggg acttctagtt cttgattctg
     1501 tcaaatgcct gagctaaatc gtttatgaga tcctgaccat actcaattcc tacagaaaga
     1561 cggatcaagc cgtcctttat gccagcctct tctcgttttt cttttggaat agacgcatga
     1621 gtcatgacag aaggaatttc cactaaactt tctacgccac ctaaactttc tgctaaagta
     1681 aatagttgga gtgattcaac aaatggaata gcagattctt cattttttaa agtaaaagaa
     1741 atcattccgc taaagccgct catctgctgc ttagcaactc catggagttc atgatcgggt
     1801 aatcctggat agtagacctt ttctactgct ggatgagaaa atagaaaatc agctaccaca
     1861 aaagcatttt tttgatgttc ctccatacga acacttagtg tcttgattcc gcgctgaagt
     1921 aaccagctat cttggggacc aagtacggct ccgatagcat tttggtaaaa tccgatctga
     1981 tcggctagat ctttatggtt agaagtcact aaaccagcta ctacatcgct gtgtccgcct
     2041 agatatttgg taccgctatg gacaacgata tcagaaccga gatctaaagg tctttgaaaa
     2101 taaggagtag caaatgtatt gtcagcaata actatcaatc catgttgatg agccagagtg
     2161 gcactttttt ctaaatcagt aatctttaga agcggattgc taggtgtttc aagataaagt
     2221 gcttttgtat tgggtttgat ggattgttct attttatcaa gattactcgt atctatgatc
     2281 gtgtactcga gaccattttt agtaagaact ttgtcaaata gacggaatgt tcctccatag
     2341 acatcatctc ctaataagat atgatcgcca gcttgaaaaa gagaaaaaac ggcatgaatc
     2401 ccagaaagac cagaagaaaa agcgaatcct cgaacaccgc cttccaaatc agcaatcagt
     2461 tcttccaatg caaaacgagt aggattacca gatcttgaat attcatattg tttaggctgg
     2521 ccgacgccat cttgccgata agtggatgtt tgataaatag gtacactgac agctcctgtt
     2581 gtgggatctt cactgatgcc tccgtggatc aattttgttt gaatgtgcat gtttctttcc
     2641 tcctataagt aaatgttttt tgataaatag cggtctgctg cgtctggaaa aatcgtaacg
     2701 acacgatgac caggtggtaa acgacgaatt tctcttaatg ctgctgcaaa agccgcacca
     2761 ctcgaacttc caactaatag tccttgttct cgtgctaact gcctagtata gttaaaccct
     2821 tctacatcag agattgtctc gatctgattg attgaaaggg gagaaagaaa cggcggaatg
     2881 aattctacac cgataccctc aatttcgtga ggggctggat caccaccatt taacacagag
     2941 ccctctggtt ctacaccgat tattcgaatg tcgggatatt tttctttcaa aaaggtagaa
     3001 gttccagcaa aggttccacc actcccaatt cctgctacaa aactatggat attttctttg
     3061 atttcatgaa agatttctgg ccctaacgta tgatagtaag cagcaggatt atctttattt
     3121 tcaaattgaa gaggcagata gctgtttgat atctcctctg caagtttttt acttttgctg
     3181 atggcaccga tgattccttg ctcactagga gaatggatga tctttgctcc caatgctttc
     3241 atcaattgtt gtttttctaa gctaaacttc tctggaacaa caaaaaccgt tcttaatttg
     3301 tatgtgagtg cggccagagc gatcccaatt cctgtatttc cggcagttgg ttcgatgatc
     3361 gtcgtttttt cattgatttt tccttgggca aatccttctt tgatcaaata actgcccaat
     3421 ctatctttga tacttcctcc aggatttaaa tattctagtt ttgcataaat agcagaacct
     3481 ttaggcatag aatagtgctg attgtcaaag cgataaagcg gtgtggaacc aatagcttct
     3541 gtaattgtcg agataatcat gtgggcctcc taaaaaaaga taataaaaaa aggagctgac
     3601 tattaaatca gctccttgaa agacatagag aaaaattgag tagataaaaa gataagttac
     3661 ctggtactca ttctatgaag ggcaattaat agacatgaca aatagtatgc tgcttttatg
     3721 caccatacaa cagcaacgat tcaattgttt ttggttgctg actgtcatgt gtatccctcc
     3781 aagtaaaatt tttattaacg atagcatgaa aaaaaataaa agtcaaaggc ttgaaagaaa
     3841 aaaatatttc gatagcatcg tttacccgtg tttatttttc tgacaaatag gcatgagacc
     3901 ttaaaagata gagaatactc tagttttctg gccggttgtc tgatacaata aagttgatta
     3961 tgataaagaa aagaaggagc aaaaataatg atctcagcaa gtgatttaag agccggtatg
     4021 actttcgtac aagacggcaa actgattaaa gttctggatg caagccacca taaacctggt
     4081 aaaggaaata cagttatgcg tatgaaactg aaagatgtcc gttcaggtgc aacatacgac
     4141 acaacgttca gaccagaaga aaaatttgaa aaagcacata tcgacacaaa acctgtacaa
     4201 tatttgtaca cgatggatga tacagctttc ttcatggatt tggaaacata tgagcaatat
     4261 gaaattcctg tagaaacagt agaagaagaa atgaaatata tcctagaaaa catggaagta
     4321 aaaatccaat ttttcggtag cgaagtcatc ggcgttcaat taccaacaac tgtcgtatta
     4381 cgtgttgtgg aaacacaacc ttccatcaaa ggtgcaacag tcactggttc aggtaagcca
     4441 gcgacaatgg aaactggctt agtagtcaat gttcctgact tcatcgaaac agatgaattg
     4501 ttggaaatca atacagcaga aggttcttat gtaaaacgtg cgtcaaaata attcgctaac
     4561 ggattgataa gaatttgaaa acagagcttg acctcttgaa aggcagatca tcggatctgc
     4621 ctttcaagag gttttttgtg gaatcagcaa attgaaaaat aaaaaagtat ttgattttat
     4681 ttatattttg aaagatgaat ggcaaaagct agagaaagaa aaaactgcac ttatttatga
     4741 agaaattgaa atgattcata aaattgaaaa tatccgaact attccgaact atattgaagc
     4801 gaaaatattt tttcatcact aaatagt
//
LOCUS       DACDAF010000127         4806 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.133, whole genome shotgun sequence.
ACCESSION   DACDAF010000127 DACDAF010000000
VERSION     DACDAF010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.133"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..411
                     /locus_tag="IVZ69_002589"
     CDS             <1..411
                     /locus_tag="IVZ69_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184608.1"
                     /translation="GLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAP
                     QEYLSRAYNDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLT
                     ELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT"
     gene            509..1882
                     /gene="tet(L)"
                     /locus_tag="IVZ69_002590"
     CDS             509..1882
                     /gene="tet(L)"
                     /locus_tag="IVZ69_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HAP8184609.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIKKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
     gene            2446..3708
                     /locus_tag="IVZ69_002591"
     CDS             2446..3708
                     /locus_tag="IVZ69_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Plasmid recombination enzyme type 2"
                     /protein_id="HAP8184610.1"
                     /translation="MSYAVCRMQKVKSAGLKGMQFHNQRERKSRTNDDIDHERTRENY
                     DLKNDKNIDYNERVKEIIESQKTGTRKTRKDAVLVNELLVTSDRDFFEQLDPGEQKRF
                     FEESYKLFSERYGKQNIAYATVHNDEQTPHMHLGVVPMRDGKLQGKNVFNRQELLWLQ
                     DKFPEHMKKQGFELKRGERGSDRKHIETAKFKKQTLEKEIDFLEKNLAVKKDEWTAYS
                     DKVKSDLEVPAKRHMKSVEVPTGEKSMFGLGKEIMKTEKKPTKNVVISERDYKNLVTA
                     ARDNDRLKQHVRNLMSTDMAREYKKLSKEHGQVKEKYSGLVERFNENVNDYNELLEEN
                     KSLKSKISDLKRDVSLIYESTKEFLKERTDGLKAFKNVFKGFVDKVKDKTAQFQEKHD
                     LEPKKNEFELTHNREVKKERSRDQGMSL"
     gene            3953..>4806
                     /locus_tag="IVZ69_002592"
     CDS             3953..>4806
                     /locus_tag="IVZ69_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HAP8184611.1"
                     /translation="MCPNSSIYSDEKSRVLVDKTKSGKVRPWREKKIANVDYFELLHI
                     LEFKKAERVKDCAEILEYKQNRETGERKLYRVWFCKSRLCPMCNWRRAMKHGIQSQKV
                     VAEVIKQKPTVRWLFLTLTVKNVYDGEELNKSLSDMAQRFRRMMQYKKINKNLVGFMR
                     ATEVTINNKDNSYNQHMHVLVCVEPTYFKNTENYVNQKQWIQFWKKAMKLDYDPNVKV
                     QMIRPKNKYKSDIQSAIDETAKYPVKDTDFMTDDEEKNLKRLSDLEEGLHRKRLISYG
                     GLLKEIHK"
BASE COUNT         1661 a          665 c          979 g         1501 t
ORIGIN      
        1 ggcttatact atagccctgt tagtacccca gcagattttc ggatgcttgc tcctattgta
       61 ttggaacaag tcttaaaaaa agctggaaca gaattgttag agccatatct tagttttaaa
      121 atttatgcgc cacaggaata tctttcacga gcatacaacg atgctcctaa atattgtgcg
      181 aacatcgtag acactcaatt gaaaaataat gaggtcattc ttagtggaga aatccctgct
      241 cggtgtattc aagaatatcg tagtgattta actttcttta caaatggacg tagtgtttgt
      301 ttaacagagt taaaagggta ccatgttact accggtgaac ctgtttgcca gccccgtcgt
      361 ccaaatagtc ggatagataa agtacgatat atgttcaata aaataactta gtgtatttta
      421 tgttgttata taaatatggt ttcttgttaa ataagatgaa atatttttta ataaagattt
      481 gaattaaagt gtaaaggagg aattaattat gaagtgtaat gaatgtaaca gggttaaata
      541 caaccaaatt ttaatttggc tttgcgtttt atcttttttt agcgtattaa atgaaatggt
      601 tttgaacgtc tcattacctg atattgcaaa tgattttaat aaaccacctg cgagtacaaa
      661 ctgggtgaac acagccttta tgttaacctt ttccattgga acagctgtat atggaaagct
      721 atctgatcaa ttaggcatca aaaggttact cctatttgga attataataa attgtttcgg
      781 gtcggtaatt gggtttgttg gccattcttt cttttcctta cttattatgg ctcgttttat
      841 tcaaggggct ggtgcagctg catttccagc actcgtaatg gttgtagttg cgcgctatat
      901 tccaaaggaa aataggggta aagcatttgg tcttattgga tcgatagtag ccatgggaga
      961 aggagtcggt ccagcgattg gtggaatgat agcccattat attcattggt cctatcttct
     1021 actcattcct atgataacaa ttatcactgt tccgtttctt atgaaattat taaagaaaga
     1081 agtaaggata aaaggtcatt ttgatatcaa aggaattata ctaatgtctg taggcattgt
     1141 attttttatg ttgtttacaa catcatatag catttctttt cttatcgtta gcgtgctgtc
     1201 attcctgata tttgtaaaac atatcaagaa agtaacagat ccttttgttg atcccggatt
     1261 agggaaaaat atacctttta tgattggagt tctttgtggg ggaattatat ttggaacagt
     1321 agcagggttt gtctctatgg ttccttatat gatgaaagat gttcaccagc taagtactgc
     1381 cgaaatcgga agtgtaatta ttttccctgg aacaatgagt gtcattattt tcggctacat
     1441 tggtgggata cttgttgata gaagaggtcc tttatacgtg ttaaacatcg gagttacatt
     1501 tctttctgtt agctttttaa ctgcttcctt tcttttagaa acaacatcat ggttcatgac
     1561 aattataatc gtatttgttt taggtgggct ttcgttcacc aaaacagtta tatcaacaat
     1621 tgtttcaagt agcttgaaac agcaggaagc tggtgctgga atgagtttgc ttaactttac
     1681 cagcttttta tcagagggaa caggtattgc aattgtaggt ggtttattat ccataccctt
     1741 acttgatcaa aggttgttac ctatggaagt tgatcagtca acttatctgt atagtaattt
     1801 gttattactt ttttcaggaa tcattgtcat tagttggctg gttaccttga atgtatataa
     1861 acattctcaa agggatttct aaatcgttaa gggatcaact ttgggagaga gttcaaaatt
     1921 gatccttttt ttataacagg aattcaaatc tttttgttcc attaaagggc gcgattgctg
     1981 aataaaagat acgagagacc tctcttgtat cttttttatt ttgagtggtt ttgtccgtta
     2041 cactagaaaa ccgaaagaca ataaaaattt tattcttgct gagtctggct ttcggtaagc
     2101 tagacaaaac ggacaaaata aaaattggca agggtttaaa ggtggagatt ttttgagtga
     2161 tcttctcaaa aaatactacc tgtcccttgc tgatttttaa acgagcacga gagcaaaacc
     2221 cccctttgct gaggtggcag agggcaggtt tttttgtttc ttttttctcg taaaaaaaag
     2281 aaaggtctta aaggttttat ggttttggtc ggcactgccg acagcctcgc agagcacaca
     2341 ctttatgaat ataaagtata atgtgttata ctttacttgg aagtggttgc cggaaagagc
     2401 gaaaatgcct cacatttgtg ccacctaaaa aggagcgatt tacatatgag ttatgcagtt
     2461 tgtagaatgc aaaaagtgaa atcagctgga ctaaaaggca tgcaatttca taatcaaaga
     2521 gagcgaaaaa gtagaacgaa tgatgatatt gaccatgagc gaacacgtga aaattatgat
     2581 ttgaaaaatg ataaaaatat tgattacaac gaacgtgtca aagaaattat tgaatcacaa
     2641 aaaacaggta caagaaaaac gaggaaagat gctgttcttg taaatgagtt gctagtaaca
     2701 tctgaccgag atttttttga gcaactggat ccaggagaac aaaaacgatt ttttgaggaa
     2761 agttataaat tattttccga acgatatggc aagcaaaata ttgcttatgc aacagttcat
     2821 aatgatgagc aaacccctca catgcattta ggtgttgtgc ctatgcgtga tggaaaactg
     2881 caaggaaaaa atgtgtttaa tcgtcaagaa ctgttatggc tacaagataa attccccgag
     2941 catatgaaaa aacagggttt tgagttgaag cgtggtgaac gtggctctga ccgtaaacat
     3001 attgagacag ctaaatttaa aaaacaaact ttggaaaaag agattgattt tctagaaaaa
     3061 aatttagcag ttaaaaaaga tgaatggact gcttatagcg ataaagttaa atcagattta
     3121 gaagtaccag cgaaacgaca catgaaaagt gttgaagtgc caacgggtga aaagtccatg
     3181 tttggtttgg gaaaagaaat aatgaaaaca gaaaagaaac caaccaaaaa tgttgttata
     3241 tcggagcgtg attataaaaa cttagtgact gctgcgagag ataacgatag gttaaaacag
     3301 catgttagaa atctcatgag tactgatatg gcgagagaat ataaaaaatt aagtaaagaa
     3361 catgggcaag ttaaagaaaa atatagtggt cttgtagagc gatttaatga aaatgtaaat
     3421 gattataatg agttgcttga agaaaacaag tctttaaagt ctaaaataag cgatttaaag
     3481 cgtgatgtga gtttaatcta tgaaagcact aaggaattcc ttaaggaacg tacagacggc
     3541 ttaaaagcct ttaaaaacgt ttttaagggg tttgtagaca aggtaaagga taaaacagca
     3601 caattccaag aaaaacacga tttagaacct aaaaagaacg aatttgaact aactcataac
     3661 cgagaggtaa aaaaagaacg aagtcgagat cagggaatga gtttataaaa taaaaaaagc
     3721 acctgaaaag gtgtcttttt ttgatggttt tgaacttgtt ctttcttatc ttgatatata
     3781 tagaaataac gtcattttta ttttagttgc tgaaaggtgc gttgaagtgt tggtatgtat
     3841 gtgttttaaa gtattgaaaa cccttaaaat tggttgcaca gaaaaacccc atctgttaaa
     3901 gttataagtg accaaacaaa taactaaata gatgggggtt tcttttaata ttatgtgtcc
     3961 taatagtagc atttattcag atgaaaaatc aagggtttta gtggacaaga caaaaagtgg
     4021 aaaagtgaga ccatggagag aaaagaaaat cgctaatgtt gattactttg aacttctgca
     4081 tattcttgaa tttaaaaagg ctgaaagagt aaaagattgt gctgaaatat tagagtataa
     4141 acaaaatcgt gaaacaggcg aaagaaagtt gtatcgagtg tggttttgta aatccaggct
     4201 ttgtccaatg tgcaactgga ggagagcaat gaaacatggc attcagtcac aaaaggttgt
     4261 tgctgaagtt attaaacaaa agccaacagt tcgttggttg tttctcacat taacagttaa
     4321 aaatgtttat gatggcgaag aattaaataa gagtttgtca gatatggctc aaagatttcg
     4381 ccgaatgatg caatataaaa aaattaataa aaatcttgtt ggttttatgc gtgcaacgga
     4441 agtgacaata aataataaag ataattctta taatcagcac atgcatgtat tggtatgtgt
     4501 ggaaccaact tattttaaga atacagaaaa ctacgtgaat caaaaacaat ggattcaatt
     4561 ttggaaaaag gcaatgaaat tagactatga tccaaatgta aaagttcaaa tgattcgacc
     4621 gaaaaataaa tataaatcgg atatacaatc ggcaattgac gaaactgcaa aatatcctgt
     4681 aaaggatacg gattttatga ccgatgatga agaaaagaat ttgaaacgtt tgtctgattt
     4741 ggaggaaggt ttacaccgta aaaggttaat ctcctatggt ggtttgttaa aagaaataca
     4801 taaaaa
//
LOCUS       DACDAF010000128         4744 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.134, whole genome shotgun sequence.
ACCESSION   DACDAF010000128 DACDAF010000000
VERSION     DACDAF010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.134"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            125..934
                     /locus_tag="IVZ69_002593"
     CDS             125..934
                     /locus_tag="IVZ69_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HAP8184612.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            974..1471
                     /locus_tag="IVZ69_002594"
     CDS             974..1471
                     /locus_tag="IVZ69_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HAP8184613.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(1856..1929)
                     /locus_tag="IVZ69_002595"
     tRNA            complement(1856..1929)
                     /locus_tag="IVZ69_002595"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1893..1895),aa:Ile,seq:cat)
     gene            2116..2439
                     /locus_tag="IVZ69_002596"
     CDS             2116..2439
                     /locus_tag="IVZ69_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184614.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            2603..2857
                     /locus_tag="IVZ69_002597"
     CDS             2603..2857
                     /locus_tag="IVZ69_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184615.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            2927..3172
                     /locus_tag="IVZ69_002598"
     CDS             2927..3172
                     /locus_tag="IVZ69_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184616.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            3248..3613
                     /locus_tag="IVZ69_002599"
     CDS             3248..3613
                     /locus_tag="IVZ69_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184617.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(3674..4237)
                     /locus_tag="IVZ69_002600"
     CDS             complement(3674..4237)
                     /locus_tag="IVZ69_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184618.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT         1506 a          833 c          794 g         1611 t
ORIGIN      
        1 ttcttaagaa tgttttttga aaaaattcat aatgacaaag caagttagtt tcattttttt
       61 aaattctcat ttaatcttaa ggtaacagga aaatagatat gtaaaaagaa agtaggaaga
      121 taaaatgaaa ctagcagcga ttgatttaga cggtaccttg cttgatcgaa atggaaagat
      181 accagaagaa aatatccaag cacttcggaa atttgatgaa aatggcggaa tcgtaaccgt
      241 cgctaccgga aggaacagca tttctgctaa agatattttt tccgaattag gaatcggtgg
      301 ctatttgatt tcttccaatg gttcactgat tgctgaaatg aaggatggaa aaatggcgaa
      361 agttctcaga cgttcaaaaa tagatagcga tacactgaga aaagccttct tctatgctca
      421 agaagcgaaa atatccatca ttgctagccg agaaacccaa gatgatcagc tgacattcga
      481 tgaatcaaat ctagtcaaag atgaccctta ttatgaacat ttcaatttac agaaccattc
      541 ttttgatcaa attttaaata tgttggaaga tccttctctt agctatctta aattagcatt
      601 aacagataag agtgaagaaa aactacagaa gctacaaaga gatctgcaag cagatggtat
      661 ccaatcagta ttctctgatc cgcatttctt agaaatcacg cctacaggta tcactaaagc
      721 tcattcactt gtttttctgg cggattacct tggaatcgaa tcgagtgaca tcatggcttt
      781 tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc gggttgagta ttgcgatggg
      841 gaatgcacag cgacaagtaa aagaaattgc aaaccaagta acactgacga atgaagaagc
      901 tggtgttgct tatattttaa aaaacttcta ttaaaaagaa taaaatgacg atatgaatgt
      961 aggaggaaag aaaatgttag ttattattga tatgcaaaat catattcttg atccaaacag
     1021 cgaattttat attccagagt cagatcaatt ggcagaacgt attgctcaaa gattagctaa
     1081 agcacgccaa aataatgaat atattctctt cacacgggat ataccagttg aactgaagga
     1141 caaagaagaa gaacgagaag atttgcaatt gatccctctt ctttctccac aagaaaatga
     1201 acgagtgatt aaaaagtatt actttacgat tccacctgaa actttagctg aaatccagga
     1261 aactttattt gaaagcaaag aagaacaaaa agagatcgaa gtagtcggga ttgaaacaaa
     1321 cttgtgtgta ctctctaatc tgataggcct gcagagtgct tttcctgaag cagacttttt
     1381 tgttgatcca atgttagtct ccagtagaaa acacggagaa tccgctttag agctgttgaa
     1441 agatttcaac gtctctatcg tcgaatcata aaaatatcta tcttcattta cgatatttaa
     1501 cacacaataa aaaaagcacg cagaactgtt ttagtcctac gtgctttttc tatcaaagta
     1561 gattggcttt tttatgacac agagtgaaac ggcaggctca cgacctcttt cttaaatggt
     1621 gttcaatcag ctgaccctcg gtattagctt aacaaacggc aaaatatgag gaactatttt
     1681 tccgtttgtt aagctaatac tcaggtcaaa acgctgattt cacaacctct tccttaaacg
     1741 gtattcaaaa gcttgcatct gcagtaataa gaacagccaa gtaaaaacat aagaagctgt
     1801 ttttacttgg ctgttcttat tacttgatgc agggcagctt tttcacaacc tcttatgtac
     1861 cttgtaggac tcgaacctac gaccggacgg ttatgagccg tctgctctaa ccaactgagc
     1921 taaaggtaca tcataaataa aatttatttt tgttactttt caactatagc acgaatgaca
     1981 aactctcaca agtttcaaaa tataagtaaa ataatattgt tattcttatt tcttttactt
     2041 gtgtcataac tattttgtta ctttaatttt tatttgctta ttttagaaaa aatgttattc
     2101 ttttatttat tctcaatgtt aggagtgatt attttgccat ttattgcgat tttattcgat
     2161 ttagttgcgg cagcagctta ttttctccaa ttaaattatc aaacctcagg aattctgttt
     2221 attggaatga tttttcaagg tgtgattacc cttttgcttc ttgtcatgat gctcagctat
     2281 aaaggaaaaa gatatgcccg tattcaaaca aaagtatttg ttaaatatgt ttccattcgc
     2341 tatgggatca tcattctttc ctttttagtg aatgcgatcg tcctcttttt atatgtattg
     2401 aattacttag atatcaatcc attgattttt tctcgataga taagacacat tcagcggaac
     2461 agttcctgct tatcagcaga aaactgttct gctttttcat ttttcattga tctattcttc
     2521 ttttattttc ctagcatttc atttgtgatg tatgcaataa catgttatct tttattatat
     2581 gaatcgttga ggagtccgtt acatgattac gttggtgaga gttttgtttt gggtgcctgc
     2641 ggtcgcactg gtcgcaagta ttgtttatct tatgaattgg aacaaagaac ggttttattt
     2701 agctattttg actcttccgg ctatctactt tatgtggaaa gtttttaatt acaactactt
     2761 tgaacccgat agtgttttta tagaagaatt atcaggactg gttttgtctt tattgatcgt
     2821 cattctttat ttgatacgtt taaataaaaa acattgagta ctattgattg catgtgtagc
     2881 tttctatagt cattataact attctactat aatgaaaggt gattaaatga gtatcgaaga
     2941 agctatttta ctggatactt tacgttgtcg tctgaatttc ttaagaactg gccgatcttt
     3001 atctcaagta gctgtttcta gcgcgttaag tattccttta ttcaaatatc gtaagtacga
     3061 agaaggagaa gaaattccaa gcatcattga attaatctat atcgctgact tttacgatat
     3121 ttccgttgat tacctaattg gtcgctcaga aacagcaagc aaactgaagt gattttttcc
     3181 agccttggtg ctggtttttt catttaacgt ctaaggttaa caatctatat ataaaggaga
     3241 catttctatg cgattatggc atgaaaaatt gatttcaaag cttcctcgtc aacagctttt
     3301 aggacaacat cgggaatgct gtgcattaag aggaaatggc tggggaaaga aacatgctac
     3361 tgtggattat gtttttcact attctcctta tagattattc caatatcatc agcttgtcat
     3421 ggatgaaatg gaaaaacgtg gttacagccc agcaccagag tggaaaaatc ctatgtatcg
     3481 tggcaaatca tgcgaagcat tttttgattt acctactgta gagcgcaacg tgccgattta
     3541 tccggaacac gatgaagttt atctagcaga atgtttagca aatttggagc aaaaaggaat
     3601 ttatcttacc taatataact agaaaagcct tctatctcct cttacttcat taaaaagctt
     3661 taaccatctt agatcaagct aaaatgtcgt aagttttagg gttatcttca tcctcacgtg
     3721 caaaactaaa agcgtactct agttttggtt catcgccaac ttccctagac ataaatgaac
     3781 atctcctgac gtggtttaaa agtaccgcat cttcgacgtc tgtatacgat gcacagcaca
     3841 gattgcttct tttgatcttt cttttgattt ttctgttgct tcttctacac cttcttcgat
     3901 tactacatcg atgcttacaa ttgcttctgc ctaatattcc catgcatcgt cgatttaagc
     3961 ctctgtagtc actgtgatcg tttccacatt ttaactcctc tgtcgtggct tcagttgatt
     4021 ttgtgatcag ttcagttgct aagccagagt cagaacaacc tgccattgct agcgttaata
     4081 ttgatagtaa aaatagtttt tttatcataa ggttcccccc ctgaaaatag actaaaataa
     4141 taacgctttc tttttttgtt ttcagacgaa aattaataat ttctaaatat tctttaaaaa
     4201 agcttataac tattatgcct tttttaatat ataacacagt tatttttaaa aataagaatg
     4261 ctaaatcact ctacaataac ggcgaaagca caaaaaataa aaaaattatt acgttattaa
     4321 aaaaacagat gaaagatcag gttttattag atctcattct ttcatcactt gaagggattt
     4381 aatgaactac tttttcctct ttgtcgtttt tatatattcg tattccttca aacagtagga
     4441 tagcctcttt caatgcttga tatttgaact gtccgttact taaaaattta gatgtgccgc
     4501 cctcttccta gaacatattc ttttttactt tttcattaat tgacagacca atcgaacgaa
     4561 actgtaaatt tcgataggat aatgattggt caaactcatt cattttcaag acatctcgat
     4621 tcatattcaa gataggaatc tttttatcaa catcacttta ttcgtatttt cctctaccat
     4681 aaaagcttca cgctccacaa aattgtttta tacactacta ttcagcccat tcaacgacca
     4741 atga
//
LOCUS       DACDAF010000129         4680 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.135, whole genome shotgun sequence.
ACCESSION   DACDAF010000129 DACDAF010000000
VERSION     DACDAF010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4680
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.135"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            58..912
                     /locus_tag="IVZ69_002601"
     CDS             58..912
                     /locus_tag="IVZ69_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003065868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HAP8184619.1"
                     /translation="MENSIYLVTEPNTQLKDCYFNFCGYSKTEPRHSFGPAIREQYLI
                     HIVLEGEGYYSINDQKYFLKKGQGFVIPPGVSTFYQADEKNPWSYVWLGLSGNLVEYY
                     LKEIGVGKNHLTFKVENLNSFKGLIFETLSYDQDNLVSELSRQKQVYKFLELLLNSAS
                     YLNEGIITKKMNPFVRQTIEIIRENAYQKLSVKDIAVSLSIHENYLSRLFKNDMGISI
                     KEYISEIKISIANDLLSSTEYSIQQISDKIGFSTVQSFSKAFKKANGVSPGVYRKRRL
                     GLGIINGE"
     gene            1009..3258
                     /locus_tag="IVZ69_002602"
     CDS             1009..3258
                     /locus_tag="IVZ69_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HAP8184620.1"
                     /translation="MYKDNEMNIIYRSENQQFHLFNQEISYIFKIPEDGKLLHLYYGE
                     NLPDNDYSHLIEMHHRPMTTYRNENDLLYSLEHLKQEFPEYGTTDFRHPAISLLQKNG
                     SRLSDFVYQGYEVEEGKPKLEGLPATYVDNNDESKTLKVYILDSVTNVQVELLYTIYR
                     DYPVITRSARVMNKGKDIQIIENISSLSLDLPDANYEWQQLSGAWGRERTIKSRTLQQ
                     GIQSIESTRGISSHQHNPFVTLKRKNTDENQGEAIGAALVYSGNFLIQAEVDTWDVTR
                     LQVGINPFGFNWKLNPGEIFTAPEAILVYSSKGLNAMSQTFHQLFRKRLARGKWREKD
                     RPVLINNWEATYFDFDEEKLVNIAKKAFDVGIELFVLDDGWFGERENDCAGLGDWHVN
                     PKRLPRGIGSLSEKIRSFGMKFGLWFEPEMVNKDSELYRTHPNWIISTPNRKPNHGRN
                     QYVLNFGLDEVVENIFDQMCKIIDESNLDYIKWDMNRPLTDVFDSHLSADQQGEVFHR
                     YVLGVYRLYEKLITKYPNILFESCSSGGGRFDPGMLHYAPQAWASDDSDAIERLKIQY
                     GTSMLYPLSSIGAHVSIVPNHQTNRITPIKTRGNVAFFGAFGYELDLNELSEGDLRIV
                     KEQIAFYKKYRTIIHNGTFYRLLSPFDDDNQTAWMVVSHDKKTAIVAHYKTLNEVNAP
                     YRRLKLKGLDNDGLYNVGQNSLRSGMELMRAGLVCSDASSGQINDQNRRPETFDFDSK
                     IWVITQEEK"
     gene            3261..4436
                     /locus_tag="IVZ69_002603"
     CDS             3261..4436
                     /locus_tag="IVZ69_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HAP8184621.1"
                     /translation="MNNQKSLLQKGAILSISLMLTSSQAINGVIPQMKQSLGISQSQS
                     ELLGTAPSITVILFILLSSYFAKRIGMKKTIILGLLLAGIGGIIPVFTATFQTVLISR
                     VILGAGLGVYNSLAVTYISSLYSGNTRATLLGIRNSMEALGQTILIFLAGVLVNINWT
                     ASFLVYAIAFPVALLFALKVPEIRDENSDIPENHVKEKMNPMVFALVLFAILLVMNSI
                     AISVRFASIATEIKGVNFNASNYLALMPILGILAGFMFGPINKWIGKGTLYLGIIFFI
                     ISNLLIAVSNGNMTFLLTGLFLSSITGSWCFPFIFSNLDKVTTKNTINFATSLIFIGC
                     NIGNFIAPIAMQLAQFLTRSTNLTAPFFVFAGIFIVILFVTFFATNKKNTRVTRGAS"
     gene            complement(4439..>4680)
                     /locus_tag="IVZ69_002604"
     CDS             complement(4439..>4680)
                     /locus_tag="IVZ69_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP8184622.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVETVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1633 a          675 c          849 g         1523 t
ORIGIN      
        1 taataatata aacataataa aacaaaaatt atccaaatct aacataggag ggtggatatg
       61 gaaaattcta tatatttagt aacagaacct aacactcagc tgaaagattg ttactttaat
      121 ttttgtgggt attcaaaaac agaacctaga catagttttg gaccagctat tcgagaacaa
      181 tacttaatac acatagtgct agaaggtgaa ggctattatt caattaatga tcaaaaatat
      241 tttctgaaga aaggccaagg atttgttatc ccaccaggag tatctacttt ttatcaagca
      301 gatgaaaaaa atccgtggtc atatgtatgg ttgggtttaa gtggcaatct tgtagaatac
      361 tatctaaaag aaattggtgt tggaaagaat catcttacct ttaaagtcga aaatttaaat
      421 tcatttaaag gattaatttt tgaaacttta tcgtatgatc aggacaatct agtcagtgaa
      481 ttgtccagac aaaaacaagt ttataaattt ttagaactcc tcttaaattc agctagttat
      541 ctgaacgaag ggataattac taaaaagatg aatccttttg ttcgtcaaac aattgaaata
      601 atacgtgaga atgcgtatca aaaattatct gttaaagata ttgctgtcag tctatcgata
      661 cacgaaaatt atttatcacg attgtttaag aatgatatgg gaatatcaat aaaagagtat
      721 attagtgaaa tcaaaatttc tattgcaaac gatctgttat catcaactga atattcaatc
      781 cagcaaatca gtgacaagat aggattctca acagtacaat ctttttctaa agcctttaag
      841 aaagcaaatg gtgtttcacc gggagtatat cgaaaacgta gattaggtct aggaatcatt
      901 aatggtgaat aaactaaaca tttgattttg ataaatattc gttactttaa acgcttacta
      961 tttatgtgag cgttttttat aatgcaataa agaaacggag gagagcttat gtataaggat
     1021 aatgaaatga atattattta tcgatcagaa aaccaacaat ttcatttgtt taatcaggag
     1081 ataagttaca tttttaagat accggaagat ggtaaattat tgcatttata ttatggtgag
     1141 aacttaccag ataatgacta tagtcatcta attgagatgc atcatcggcc tatgacaacc
     1201 tatagaaatg aaaacgattt gctatattcg ttagagcact taaaacaaga atttcctgaa
     1261 tatggtacaa cagattttag acatcctgct atttcattac tacagaaaaa tggctctcgc
     1321 ttatcagatt ttgtctatca agggtacgaa gtggaagaag gaaaacctaa actagaaggt
     1381 ttacctgcta cctatgttga taataatgat gaaagcaaaa cattgaaagt ttatatttta
     1441 gattcagtta caaatgttca agtagaatta ttatatacaa tttatagaga ttatcctgtt
     1501 attactcgta gcgcgcgagt tatgaataaa ggaaaagata ttcaaataat cgagaatatt
     1561 agcagtttat cattggattt acccgatgca aattatgaat ggcaacaatt atctggtgct
     1621 tggggtagag aaagaactat taagtcgcgt actttacaac aaggaattca atcaatcgaa
     1681 tctactcgag gtatttcaag ccatcagcat aacccatttg ttactttaaa aagaaaaaat
     1741 actgatgaaa atcaaggaga agctattggt gcagcactag tttactcagg aaacttctta
     1801 attcaagcag aagtagatac atgggatgtt actagactac aagttggcat caatccattt
     1861 ggatttaatt ggaaactcaa tccaggagaa atatttacag caccagaagc gattctggtt
     1921 tattcaagta agggtttaaa tgccatgagt caaacttttc atcaactatt tagaaaacgc
     1981 ttagctcgtg gtaagtggcg agaaaaagac cgtcctgtct taattaataa ttgggaagca
     2041 acatattttg attttgacga agaaaagttg gtaaatattg ctaaaaaagc atttgatgtt
     2101 ggtattgaat tatttgtatt agatgatggc tggtttggag aaagagaaaa cgattgtgca
     2161 ggattaggag attggcatgt aaatcctaaa agactaccta gaggaatcgg cagcctttca
     2221 gaaaaaattc gtagttttgg tatgaaattt ggtttatggt ttgaacctga aatggtgaat
     2281 aaggatagtg agttatatcg cacacatccg aattggatta tttctacacc taatcgaaaa
     2341 cctaatcatg gtaggaacca atatgtatta aattttgggt tagatgaggt tgttgaaaat
     2401 attttcgatc aaatgtgtaa aatcattgat gaatcaaact tagattacat taagtgggat
     2461 atgaatcgtc cattgactga tgtatttgac agtcacttgt cagcagatca acaaggagaa
     2521 gtattccaca gatatgtact aggcgtatat cgcttatatg aaaaacttat aacaaaatat
     2581 cctaacatac tatttgagtc ttgttcatca ggtggtgggc gctttgatcc tggaatgctt
     2641 cactatgcac ctcaagcttg ggctagtgat gattcagatg caattgaaag gttaaaaatt
     2701 caatatggaa ctagtatgct gtatcctctt tcgtctattg gtgctcatgt atcaattgtt
     2761 ccaaatcatc aaacaaaccg tataacacct ataaaaacta gaggaaatgt agcttttttt
     2821 ggtgcatttg gatatgagct tgacttaaat gaattaagtg aaggcgattt gaggattgta
     2881 aaagaacaaa ttgcctttta taaaaaatat agaaccataa ttcataatgg tactttttat
     2941 agactattat caccattcga tgatgataat caaaccgcgt ggatggttgt tagtcatgat
     3001 aagaaaacgg ctattgttgc tcattataaa acattaaatg aggtaaatgc tccttaccgc
     3061 cgactgaaat taaaagggtt agataatgac ggactttata atgtaggaca aaatagtttg
     3121 cgatctggaa tggaattgat gagagcagga ctagtctgtt cagatgcatc tagtggacaa
     3181 ataaatgatc agaatcgacg cccagaaaca tttgattttg attccaagat ttgggttata
     3241 acacaggagg aaaagtagag atgaataacc aaaaaagctt acttcaaaaa ggagcaatct
     3301 taagtatttc actaatgtta acaagctctc aagcaattaa tggtgttatt ccacaaatga
     3361 aacagtcttt ggggatatca caaagtcaaa gtgaactttt aggaactgca ccaagtataa
     3421 ctgttatttt gtttatctta ttatctagtt actttgccaa aagaatagga atgaaaaaga
     3481 caataatttt aggtttatta ttagctggta taggaggaat tattccagta tttacagcta
     3541 ccttccaaac cgttcttatt agtcgagtaa tattaggtgc cggtttagga gtatataatt
     3601 cattggctgt gacatatatc agctctttat actctggcaa tactagagca acgctattag
     3661 gtattagaaa ttcaatggaa gctttaggtc agacaatcct tatttttctt gctggagttt
     3721 tagtgaacat taattggacg gcttcgtttt tagtctatgc aattgcgttt cctgtagctc
     3781 tcttattcgc gctaaaagtt cctgaaatta gagatgaaaa tagtgacata cctgaaaatc
     3841 atgtaaaaga aaagatgaat ccaatggttt ttgccctagt tctatttgca atcttactcg
     3901 taatgaatag tattgctatt tctgtacgat ttgcatcaat tgcaactgaa attaaagggg
     3961 taaactttaa tgctagtaac tatttagctc taatgcctat cttaggaata ctagcaggat
     4021 ttatgtttgg accaataaat aagtggatag gaaaaggaac cctatacttg ggaattatat
     4081 tctttataat ttcaaatttg ttaattgctg tgtcaaacgg taatatgacg ttcctgctaa
     4141 cgggtttatt tttatcaagt ataacaggat catggtgctt cccatttatc tttagtaact
     4201 tagataaagt cactacaaag aatacaatta attttgctac ttcattgatt tttattggct
     4261 gtaatattgg taattttata gctcctattg ctatgcaatt agcacaattt ctaacaagaa
     4321 gtacaaattt gactgctcca ttttttgtat tcgcaggaat atttattgtg atcctatttg
     4381 taacattttt tgcgacaaat aaaaaaaata ctagagtaac ccgtggtgct agttaatttt
     4441 aatatcctaa agaatatctc aaagttcctt caaaacgtcg ttgtgctcga cttaatagaa
     4501 cactgtaagc cagtaatatg ctttcaaatc tactctctag ccctttaaca gaacgtgagt
     4561 tgaaattttg acaacctaat ttttctaagg aagaaaaaac agtctcaact gtttttcttt
     4621 gttttccaag taagctgtgg tctagttttt ctgatttatc catgttttta cgtggcggaa
//
LOCUS       DACDAF010000130         4492 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.136, whole genome shotgun sequence.
ACCESSION   DACDAF010000130 DACDAF010000000
VERSION     DACDAF010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.136"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(213..443)
                     /locus_tag="IVZ69_002605"
     CDS             complement(213..443)
                     /locus_tag="IVZ69_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HAP8184623.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(673..1491)
                     /locus_tag="IVZ69_002606"
     CDS             complement(673..1491)
                     /locus_tag="IVZ69_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HAP8184624.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            1652..2341
                     /locus_tag="IVZ69_002607"
     CDS             1652..2341
                     /locus_tag="IVZ69_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HAP8184625.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            2355..3857
                     /locus_tag="IVZ69_002608"
     CDS             2355..3857
                     /locus_tag="IVZ69_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010759843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8184626.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            3870..4346
                     /locus_tag="IVZ69_002609"
     CDS             3870..4346
                     /locus_tag="IVZ69_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HAP8184627.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
BASE COUNT         1501 a          647 c          791 g         1553 t
ORIGIN      
        1 tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat gaactaataa
       61 ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc ataaactttt
      121 aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca taacattgaa
      181 gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt cttataaaca
      241 agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt tatagaaaac
      301 attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc agtaggttcc
      361 tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt atttaagaga
      421 ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta cacgtttttc
      481 tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc aagaaccgta
      541 ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa taagctatca
      601 agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta ggtttagcta
      661 agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt tttctcttaa
      721 ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat cacaaatata
      781 aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa tggctgtttg
      841 taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta tagcaataat
      901 ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg ttttcccaga
      961 taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt gggcttgaaa
     1021 atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat tttctaaatc
     1081 aagactagta tttccactag atcccactcc aaatatatat atgttttttg attgagtgat
     1141 cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg aatagagagc
     1201 ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat gttctttttt
     1261 ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag aaaaaccaat
     1321 tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct taatatcact
     1381 catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga cttttttttc
     1441 agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca tacaaactcc
     1501 tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact cctaaatact
     1561 ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag ttattatcca
     1621 aaaataataa aaaattggag cgtttaggat aatggataaa aagaggtttt tagatcttat
     1681 ttcaaaaggt ttgattgttt catgtcaagc attacctggt gaaccatttt acaaagagga
     1741 agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag ttggtatacg
     1801 tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac caatgattgg
     1861 aattattaaa agagattatc caccagaatc tccattcatt actgccacta tgagagaagt
     1921 agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc ttagaaatcg
     1981 acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat atcctcatca
     2041 gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata aagcaggaat
     2101 agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac aagatgggcc
     2161 agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg ctgagggaag
     2221 gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag gtattgttgt
     2281 gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag cattaagtta
     2341 gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc atgttaccaa
     2401 ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta acaaatgaga
     2461 gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt ttaagtatta
     2521 tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca attggtattg
     2581 ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga gtagcttatt
     2641 tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa gatgcaacac
     2701 tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt ttacacaatc
     2761 gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca agatttattc
     2821 cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta atttggccac
     2881 caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt agtttaggaa
     2941 cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac cacaccattt
     3001 accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga tcaacaattg
     3061 ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact ggtctgttta
     3121 cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttggg ttaccagcag
     3181 catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat ggtgggcttt
     3241 attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt gaatatatgt
     3301 ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga ttatcttttt
     3361 attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt ttgatcgact
     3421 ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa ttaattcctt
     3481 ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc aaaaaattta
     3541 aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa gtaataaaca
     3601 aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt ggaaaagaaa
     3661 atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg aatggggaga
     3721 ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa gtgaagggtg
     3781 gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc aatcaaatat
     3841 taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag aaaaaacaag
     3901 aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta aatgatcctg
     3961 tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt tcaaaaattt
     4021 atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct attaatataa
     4081 aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt gaattacaag
     4141 gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa acctcgttgg
     4201 ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt atagttgttt
     4261 ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt gctcatggga
     4321 attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa aataagctaa
     4381 ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt ctgttcattt
     4441 ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt aa
//
LOCUS       DACDAF010000131         4461 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.137, whole genome shotgun sequence.
ACCESSION   DACDAF010000131 DACDAF010000000
VERSION     DACDAF010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.137"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            574..1008
                     /locus_tag="IVZ69_002610"
     CDS             574..1008
                     /locus_tag="IVZ69_002610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184628.1"
                     /translation="MKNKIIKIITCLFLFGMIVGASTPLNLFPFSARGIKVEAASSRY
                     NHNHRGFTCYKMNYYVTNKMCRDLKKNYNKLKTPAQIASFIPIGGVGTWVITNAFSSA
                     VDAMNVFVRAANQGKGVQLTYNAHFSNTTSYQYNDYARYVIK"
     gene            2298..3221
                     /locus_tag="IVZ69_002611"
     CDS             2298..3221
                     /locus_tag="IVZ69_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP8184629.1"
                     /translation="MANEIVKYENRLNHIPLRKFNSREMNLFFSIASRVREKGVDEII
                     FSFHDLKKLSGYTERGEQFIKDLSSTYDKLLSINAWNDDGNTLTKFVAFTKYSIIRDK
                     QLVIISVNPEFKGLFNQLKNWTRFNLEQFTNLDSTYSKTMFRLLKQYRTQGWTEFSKE
                     KFFDLLDIPKSYWNSPSNIDKFILRPIKEELTPLFKGLTIRKKYGKGRGKPVIGYRFT
                     WKAEINHADDFSKGKQEDLRIKLFNIDHNGELTREEKWRAKDRILNLPLGTHEADFKQ
                     QQQTEEKQAEKRELSNKLKQDLLGNLQNLFD"
     gene            3237..3776
                     /locus_tag="IVZ69_002612"
     CDS             3237..3776
                     /locus_tag="IVZ69_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HAP8184630.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
BASE COUNT         1664 a          667 c          758 g         1372 t
ORIGIN      
        1 aaaaaaaact gtgttggtac tgggttctat ttctctagga atattaggtt ttagccccat
       61 gctattatcc gtaattggaa aaaacaattc caacagagaa cttaaattga attcaaatta
      121 ttacaacagt cctaacgaag aattgtttgt aaaagaaacg gataaataat aaaaaagact
      181 gctcttccga gcagccagtt aaaaaataat gagtgtttat tcttgaaaaa gcaacgcgct
      241 tataaagcgc taccaaaaat ttatcatatt ttatgaaaaa taacaatcca gtaaaaaatg
      301 actggtaaaa attcacaaag aaacggaaag aagcaactgc agaaaatcaa gccttaaaaa
      361 gagcttttta cctagaccaa ttaaaaatca caaagtgagc ccctgtatcg gttgatacaa
      421 gggctacttg gcatactgta cattatgtct actaaccttt aaaataacac gttttataaa
      481 ataaaccctc ttgacaatat ttaattttct gattattcta aatatataca gaaagcgctt
      541 tcctaggatt ttatatctaa ggaggaagta acaatgaaaa ataaaattat taaaattatt
      601 acttgtctat ttttgttcgg tatgattgtt ggagcaagta ctccgttaaa tctgtttcct
      661 tttagtgcta gaggtataaa agtggaagct gcaagttcac gatataatca taatcatcgt
      721 ggatttactt gctataaaat gaactattat gttactaata aaatgtgtag agatttgaaa
      781 aaaaattata ataagctaaa gactcctgct caaattgcat cttttattcc tattggtgga
      841 gttggaacat gggttattac aaatgctttt agtagtgctg ttgatgcaat gaatgtcttt
      901 gtaagagctg caaatcaagg aaaaggtgta caattaacat ataatgctca ctttagcaat
      961 acaacatcat atcaatacaa tgattacgct cgttatgtaa taaaataatc agaaagtgaa
     1021 actatctcat gaataaaaag attttagctg taattatttc aataatagtt ttaatcacta
     1081 tgttcttcat atttaggcta attttcaata taagcttaca aaaaagtatt ctttatctaa
     1141 ttcctatagc atttatctta gcaattttta gaagtattta cggaaataaa aactctaaat
     1201 agctaaaaat aaatcatact aaattttaca aaaagtggct agcattttct agccactttt
     1261 tgtattgtgg agcgtgggtt ttgaggggga ttcaaggggg agcttgcgcc cctttgacaa
     1321 gcggttattt gcaccaaata cggaggtatt tggctagcaa atatagagct tgccaaaccc
     1381 ttttagtgag ttttgtagaa agtaccttta aaggtacttt cacattacga acgatacgtc
     1441 cgtaggacgt actgaaaggg tgggacttat gagcaaatta atgcaaaatt tggctagcaa
     1501 aaaagctaaa aaatatatgc taataatcga gcgaaataaa cactttttca agtgagcgaa
     1561 tccgccatga caaagctgaa gcagtttatt tcagctttgt catggcgtgt gccgactttt
     1621 ttaaaagtct aggcacacga gcaaatatct ttatcaagct ctaatttgcg ttttaagacg
     1681 tttgaaacgc ctaagtatat aaatatataa gaataggttt aagagtgctt aaatcgaatt
     1741 ttagagggca tttagacaat tttagggttg ttagggcttg ccctgaccgc ctgtaaggcg
     1801 ttttaagaac aagataaggg atttatacta ggactgtctt aaaatgtctt aaacgaacgc
     1861 tcagagcttc tcaaagggtt ccttatgaac ggcttttagc aaaggagccg gaggcgactg
     1921 cgcagtataa tgtgagagca gagcgatcac acctttttag cgaaccgtag ggagcaaggt
     1981 ttggaattgg cagttttgat aaattcgcga acctgtttag agaaaaaagg agtgattttt
     2041 taggcgggaa aattagcctc ccctcttttt atatctcttt ttatatctct ttttatatct
     2101 cttttatgtc ggctgtgtcc ttactctccc aagcaattca gagttttttc aagtaggttt
     2161 tctacgcttt tcaagtaggt tttctacgct tttcaagtag gttttctacg cttttcaagt
     2221 aggttttccg acattattga gtatttttat aaagtatgtt acttttattt catactttat
     2281 aaaagtagga gaagcttatg gcaaatgaaa ttgtaaaata tgaaaataga ttaaatcata
     2341 ttcctctgag aaaatttaat agtcgtgaaa tgaacttatt tttttcaatt gcttcacgtg
     2401 tacgtgaaaa aggtgtagat gagattattt tttcatttca cgatttgaaa aaactaagcg
     2461 gttatacaga acgtggggaa caatttataa aagatcttag tagcacgtat gacaaattat
     2521 taagtattaa tgcttggaat gatgatggaa atactttaac taaatttgtt gctttcacaa
     2581 aatatagcat tatacgagat aaacaacttg ttataatttc agttaatcca gaatttaaag
     2641 gactttttaa tcaattaaag aactggacaa gatttaatct agagcaattt actaatttgg
     2701 atagcacata ttcaaaaact atgtttcgat tattaaaaca atatcgaact caaggctgga
     2761 ctgaattttc caaagaaaaa ttttttgatt tactagatat tcctaaaagt tattggaata
     2821 gtccgtcaaa tattgacaaa tttatcttaa ggccaattaa agaagaactc actcccttat
     2881 ttaaaggatt aactattcgt aaaaaatatg gtaaaggtcg aggtaaacct gttatcggtt
     2941 atcgttttac ttggaaagct gaaattaacc atgctgacga tttttccaaa gggaaacaag
     3001 aagatttacg tataaaatta tttaatattg atcacaatgg agaattaaca cgagaagaaa
     3061 aatggcgcgc taaagatcga atactaaatc ttcccttagg cactcatgaa gctgatttta
     3121 aacaacaaca acaaactgaa gaaaaacagg cagaaaaacg agaactttca aacaaactca
     3181 aacaagattt actaggaaat ttacaaaact tattcgatta agcttaagga gtatttatgg
     3241 cagataaaac aatcaaagaa cttgcggaag aattaggagt tagtaaaaca gcaattaaca
     3301 aaaaagtttc tgacaaaaat cgaaaacttt ggtttgcaaa aaacggaaac aagtttgtga
     3361 ttaacgaaac cggtcaaaaa gctataaaat caatgttttt agtcgataac gcaaacttaa
     3421 atcgaaaact agttggcgaa aaatcaaaaa ccaaaaacca taaaaacacc aaccaagttt
     3481 ccgaattaaa actcctttct ttcctagaaa aacagttaaa tcgaaaagat atacagctac
     3541 aagaaaaaga taatcaaata aaacaaatgc aaaaattact cgaccagcaa caacaactca
     3601 ctctacaagc gaaccaacaa attgagaacc tacaagaaca gctccattta acttatacag
     3661 aagaaactcc aacaaccgaa tcaactgcct tttctgaaaa aaaagcagac aatacacaac
     3721 cacttattga aaaaaagtgg tggcaaattt ggaaatctaa tagaaccaat ctctaaaatt
     3781 ttctagaagt tagttcggat agtagaggaa aaagttgtac tacctgatgg ggagatcact
     3841 caaattttta tgagaaagaa aaaatagttt acaactgtaa acaatcaatg tttatagttg
     3901 taaactatca aactatatgg tgacttattg cttaaaatag gttgaaatct cactcaattt
     3961 ttggtggaaa aacaaaataa attctaatcg attttgttga aaaagtcata aaaaaacaaa
     4021 tgtgatttta acaaaatttc aaaaaaatcg tttgaaattt cgtttatttt ttttgagaat
     4081 tttgatcatc gtagggtcat tgtagaatca ttatgagatc atcgtgggat catcgaataa
     4141 agtatgggaa aggcttgcgg tgcttggtat taagggcatt ctccgcctcc caggttcttg
     4201 accattttct cttataagtg ggatttttac cacgttgaga gaaaatggtc aagaacctgg
     4261 gaggcggaga aaacatacca agcaccacaa gcaaaaaaag ttagagtaac ttccaaaaaa
     4321 gaaaaatttt ttagaacaac ttttgaaaat ttaattttga tttatatccg ttcaatttaa
     4381 acatttgata aactgaaggc tagtatttaa aatgtgtata caagtggtag cgttaaaaaa
     4441 agtggaggta taacctatgt t
//
LOCUS       DACDAF010000132         4428 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.138, whole genome shotgun sequence.
ACCESSION   DACDAF010000132 DACDAF010000000
VERSION     DACDAF010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4428
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.138"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            274..1005
                     /locus_tag="IVZ69_002613"
     CDS             274..1005
                     /locus_tag="IVZ69_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HAP8184631.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            1150..3177
                     /locus_tag="IVZ69_002614"
     CDS             1150..3177
                     /locus_tag="IVZ69_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lectin"
                     /protein_id="HAP8184632.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGHSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            3285..4382
                     /locus_tag="IVZ69_002615"
     CDS             3285..4382
                     /locus_tag="IVZ69_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HAP8184633.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT         1551 a          716 c          923 g         1238 t
ORIGIN      
        1 agtctaggca gtcaagtcac attttgatag ataggagggg gacttacgaa ttattttaaa
       61 ggctatgaca gctgtatttc tagattgtgt ttgcatcaag ttgcaataaa aactagaaat
      121 caaatcgggc tgataatcat ttataactaa tcgatacata ggaccaaata taggtctatg
      181 ttcttttatt tcataagtat cgtaaaacag aattttgcta tggattaatc caatcgactg
      241 atatgtttag taaataaaga aagaggaatg tcaatgatga aaaaagaaat cgtattaaca
      301 gcagcaatga tgttattcag catggtagca agtacgactt ttgtttctgc aactgaagta
      361 tacccaaagg aatataacac agaaggaacg attacatttg aagcaggaga tgagggtgta
      421 actcctcctg ttgatccaga gaatcctgat cccaataaac ctgtcgatcc atcagatcct
      481 ccaagccctg gaacaggagg ggcattatcg attgattatg gatcaaaatt caaatttggg
      541 actcaaaaaa tttctactgc ggataaaacg tattatgcag ctgctgatgt gatgaacgat
      601 gggtctagaa aaccgacata tgtccaagtg acagatagga gaagtacctt atctgggtgg
      661 aaattaagtg tctctcaacc agaacagttt aaaactgcca gtggggatga actagttgga
      721 gcacagctga aatttacgaa agggcaggct gtttctttgg ttgatccaac atatacgccg
      781 caaacggtga attctgaatt aacgttgaca ccgggaggaa acaatacgtt agcaattaat
      841 gctaaatcag gaacaggtgt ggggacttgg gtctatcgat ttggtgcaaa tgaaaatgaa
      901 aatcaagatg cggtacagct ttcggtaccc ggtaaatctg tcaagttagc gcaacaatat
      961 tccactaaat tagtttggac attagaagat acacctaaca actagtttac tgaaaagaac
     1021 tgttaaaaat aaatacgtag tcatattgtc ttgcgaggta atcgagcaaa aattgtcaaa
     1081 ggctaggcta aatttgtttg gatacgaata gttcatctag gaatttaacg atcaggagga
     1141 aaagatatat tgaaaaagag gaggatcgtg ctcattttaa gcagtctctt agtgactaat
     1201 atctttccga tcatagggta ctctttggaa ttgaatcagt tggagcatgg aaatagaaga
     1261 gacgaagaaa gcaaactcac ttcgacattc gacagtttaa tagaatccaa ccagacacaa
     1321 gaaagcagtg aggatttaag tatttcgagt agtggagaga ccactgacaa cgtagaagct
     1381 gagggttcgg acaaacaagg actagaagat gcaccaattt ctgcggttga gctgcctgac
     1441 gatcccaata ttatttctat cgataaaatt tttcaaacac ctatcggtac tagcacgtcc
     1501 atattggaaa atgggaagtt actgcagttg aacccagcag aaaggtctca aagaggagct
     1561 atttggtcaa ataagaagat tagtttactc tcggatttta catttaaatc ttatttatac
     1621 ttaggaaatc aacgagatag agcgggagat ggcatgacct ttacattgac tggcgatcct
     1681 agaatggcta gtaatcccag tcaagttatt ggatcgccag gtatgggaat tggctcatat
     1741 tctactcgtt ctggccaacc ttacattgcg aatgcgctct cgattgagtt tgatacgtat
     1801 aaaaatagtg gttcttctga tcgaatggat cgagagataa ctgctgataa tagagggcat
     1861 ggacatgtcg cttttgtcac gcctaaacca aataataata attattctgg agagcatact
     1921 ggcgtgacgg tagctcctac atttctttct aatggcacat ggcgcttgtt aataattaaa
     1981 tgggacgcgg agcaaagaag tcttacttat gatttggaag gtgtcggtca ctcttctcgg
     2041 attatacctg atctcattag gcagtttggt tctacagaag taaattgggg gtttacttct
     2101 tcaacaggta ctttttttca agaaaatgct gtcgctgtca cgcgacttcc atcgaatgtc
     2161 acatcaacag ctgatgtaaa agtcaacgat agtgattatg gggccatcgc tgaagctgga
     2221 ggaaacgata agataactat cagaaataca ttgaaggtcg agggggattt tcttgaatat
     2281 aagaaaatgc agactagtat cgacctccca caagaattaa ctattcccga gcatatcttg
     2341 atcaatggaa atcaaattga tgccaaagat atcttgataa ccggaaatcg agtcacgcta
     2401 aatctgacag attattttat tgctggagat acgttaataa tcgaattgga gacaactttg
     2461 caggaagtaa ttcctgaaaa agtactcact atgcattttg aataccttga aaacgggaat
     2521 ttgattgagc aatcgaatga aataaaccta aagatcgcaa agctgaagga gatagatatc
     2581 catgtttatt ataaagataa agacagtcag attgatattg ctgaaatgaa aacaatcact
     2641 gggaaaatag gagagaagta taaagaaact cctattgata ttgaagggta tgtttttgac
     2701 tcggattcag cgaatacaga aggcatcttc tccgaaaata cagaggatat ctatttttat
     2761 tacagaaaag gcaaacttta tctctcaact gctcctcaat atgtcaattt tggaaaacat
     2821 aaaatatcca gtagaccatt aagtgaattc ggacagtttt caggtgggtt gaaaattata
     2881 gatgaacggg cttttggaag ttggaaatta caattgaaac aagagaaagt tcttacaaat
     2941 ggagattttg agcttccaga agctctttcc tttgttacct ctgaaaatac aacggttata
     3001 gggacatccg ctgttacgat tttcgaaagt gatcaaaagg gtgaaagcga tttgtcctct
     3061 cttttagatt ctacagctca tcgtggaatc agaatagata ttcctgtaga aaaccaaaga
     3121 atcggaacct ttgaggggaa actatcttgg atacttgcag atgtcccagg aaattaacag
     3181 gaagagaaga atataacaaa attattgagt ttcaagaagg gcacaggtac cataggctct
     3241 tgtgtcccac agagacaaga ttttgttata gtcttctctt acatatgatt aaaggagcga
     3301 ttttcttgag accaaaacaa caattattta taacactcct agttatttta ggggcacttt
     3361 ttaacaatat atcagtgtca gctagtgcat ttaatttttc agtgacgccg ataacttcag
     3421 agaatcaaat cgacaagaga aaaacttact tcgatcttca acttgatccg gatcaggaag
     3481 tagaagtaaa agcggaattg agaaatgata cagaaaaaga agtgaaaatc gatatttctg
     3541 tgaatagcgc aaccaccaat tcaaatgtga tggttgaata cggaaaaaac gagattgaaa
     3601 aagacatgag cctgatcttt gatctggtag attatgtgag ctatccacag atagtgacgc
     3661 taaaacctaa aagtgtccaa accgttgctt ttcatgtcag gatgccgaat gagcgatttg
     3721 atggtgtatt ggctggtggg atcacattcc aagaaatcca gacggaaaag gaccaaacag
     3781 aaactaagga tcaaagctta tcgattgaga atgaatacac ctatattatt gctttgttga
     3841 tgcaacagac actgaacgaa gttgctccga accttactct tcatgaagtt aaaccagatc
     3901 aaatcaatgc aagaaatgtc atcttagcaa acgttcaaaa tgatcaaaaa acctatatca
     3961 atcaagtagt tattgaaaca aaaattacaa aaaaaggaca ttctgaagtt ttatatcaag
     4021 aggaaaaaga aggattgcag attgcgccga atacaaattt ttcttttcca actgctttaa
     4081 atggtcaacc gctaacccca ggtgaatatc accttacaat gactgtttta ggaaatgaaa
     4141 atgaaaatgg aaaattttcg agaaaaaaag gaaatactac gatcaactat accaatcaat
     4201 gggtatttga aaaagatttt acaatagacg gaaaagtagc caaggaattg aacacgacgg
     4261 atgttacgat taaaaaagac aataattgga tttatatctt agtagcttca cttttcttat
     4321 tgtttatttt attatgcata cttttgtttg ttttgagaaa aaaagaagag aaagaaaagt
     4381 aaggttaaga taacaaatag taaattttta ttattgtagg atggttgg
//
LOCUS       DACDAF010000133         4425 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.139, whole genome shotgun sequence.
ACCESSION   DACDAF010000133 DACDAF010000000
VERSION     DACDAF010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4425)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4425)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4425
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.139"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            690..1658
                     /locus_tag="IVZ69_002616"
     CDS             690..1658
                     /locus_tag="IVZ69_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP8184634.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADVRNHDLDVRRYMGKVEY"
     gene            1669..2484
                     /locus_tag="IVZ69_002617"
     CDS             1669..2484
                     /locus_tag="IVZ69_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HAP8184635.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKEIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            2552..3262
                     /locus_tag="IVZ69_002618"
     CDS             2552..3262
                     /locus_tag="IVZ69_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HAP8184636.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYIMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            3298..>4425
                     /locus_tag="IVZ69_002619"
     CDS             3298..>4425
                     /locus_tag="IVZ69_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP8184637.1"
                     /translation="MKQILRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKN"
BASE COUNT         1490 a          661 c          921 g         1353 t
ORIGIN      
        1 atacaaataa ttcaccaaaa aggtgagtaa tgccattttt gaaaattgag cttgttttat
       61 gtctacatct gtatccgtat ataatccaaa ggattataaa ctcagaagag tctttatttt
      121 ttctgaatat aactactgta tcaaaaacaa tcgattatga gacaaaacaa aatgacctct
      181 tttatttaag aaaggaggtc attttttgta tcataaattg tattaaaatc aatgtatcac
      241 tttttaatca gttttaagac cataaattgc gtactaaaag aaattctgca attcaaaata
      301 aagcatttta agccattttc aaatttaagt gcacccatct acccgtcaaa tcactttatt
      361 ttccactcca gtagtttcct aattcaactg tgtgcaaaaa cgatttcttc taaacaaatc
      421 aagacaaact tataaacctt catcccagca ccataattat ttaaatcata ggcatttttc
      481 gaaattagta tatgtactca agtttcactg cagattattt atatttttta gagaaataaa
      541 tttttcctat tgacaaacac aaagaaagcg gatacaatgc aattatgtca catgacgtta
      601 tatgacgtta tgtgatatct ttacatttaa tcagttactt ttattttgga taaaattaac
      661 atttttaaaa ttttaaggag gaaatgttga tggatgtagc aaaaacggtt aacgcaattg
      721 tagaaaaaaa tgatggagag atttctggaa tttatttggt ggcttgtggc ggttcgctgg
      781 tagatatgta tgtctcagat tattttctta aagccgaagc atcgaagtgt attacaggct
      841 tatatacagc gaacgaattt aaccatgtaa ccccaaagca attagatgat aaatctgttg
      901 tcattctatg ttctcatgga ggaaatacag cagaaacggt aaaagcagga gaagtcgctc
      961 aagctagagg agctgtgact gttggtctga ctcataataa aactgcggat ttattaaagg
     1021 tttctgatca tagtttcctt tacgaatggg gagatgatgc aaaaatagtc aataatccta
     1081 tggccatcat tcttgattta actgtatctt tggtcaatgt taccgaaaca tttgaacatt
     1141 acggtaaatt cagagaaggc atgaaggtta tcgataccgt aattgaaaat ggcattaagc
     1201 aggtgcagga tcgtattaaa gtgtttgctg ataagtacaa agatgaaaca atgttttata
     1261 tcttaggtag tggaccatca tatggacatg cttatggttt ttcaatttgc tctttgatgg
     1321 aaatgcaatg gcttgattca acttctgttc attctggaga attcttccat ggaccttttg
     1381 aagtaacaga caaagatacg aattttattc tcttgatgag cattggacgc actcgtgctt
     1441 tagatgaacg ggcaaaacga ttccttgata aatatgcaga aagagtagaa atcgttgatg
     1501 caaaggaact aggattggat atgatatcag atgaagtttc tgaattcttc aatcccattt
     1561 tattctacag tattctttca gaatatcgtt cagctttagc agatgtacgc aatcatgatt
     1621 tagatgttcg tcgctatatg gggaaagtgg agtactagga ggattaaaat gaaggtatta
     1681 ggcttaggtg ataacgtcgt cgataaatat gaaaatctgg gaattatgta tcctggagga
     1741 aattcattga attttgcagt ttttgcaaaa aaactgggac atgaaagtag ctttatggga
     1801 gtttttggct cagatgagga ggcagctcat gttttatcag caataaaaga aataggactg
     1861 gacaacagtc actctcgctt tgaaaaaggc gagaatggct gtgccagagt gaagattgat
     1921 gagggcgacc ggattttcct tggcagcaat tcgggaggtg ttactcgtga atacccgatt
     1981 cagcttactg aagaagacag agaatattta aaccagtttg aattgattca tatgggatta
     2041 tatagccatg tcaatcatct attagaagag ttacaaaatg tttctggaaa gatttcttat
     2101 gatttttctg acgactttac ggaagaagag gttcagcggg caattgataa agttgatttt
     2161 ggcttctttt ctatagaaga cttttccgat gaagaagtaa agcagttttt gatgaagcat
     2221 ttttgtgagc gaaatgatgt attgattgca acccgaggag aaaaaacggc tattggttat
     2281 gatggagcaa agttttatga agtgaacccc gtgctagaag aaccagttga tacaatggca
     2341 gcgggagatt ctttcttaac agctttccta ctttattttc tcgaagggga cgatatagtc
     2401 accgcgatga aaaaggggaa tgaatttgct gggaagtctt gtctggttga cggttcgttc
     2461 ggctttggta ttcattacga ttgagcttgt tttaaattcc tgcatttgat aacctaaaga
     2521 aagaaatccc ggtaaagtgg aggttaaaaa aatgctggat acaaatgcac aattaccatt
     2581 gtacttacaa ttaaaagaaa tattaaaaaa taaaatcaat acaggggagt atcccgagaa
     2641 tacgaaaatt cccgctgaat cagagctgat agaaagttat gaggtcagcc gaatcacagt
     2701 gagaaaagca gtagaagaac tggtagaaga agggtaccta cttaaaaaac aagggaaagg
     2761 aacttttgtc aaccggcata aagtttttcg taaaattgaa tatattatgg gtttcagtga
     2821 gagttgtaaa tctaatggtt ttacaccgac tagcattgtt ttggaacgca agatcattcc
     2881 agcaactgaa gggatggcaa aaaaactcga tatcgctcaa ggtgatgatg ttttatatat
     2941 ccagagaaag cgaatggcgg ataacatccc cattatgtta gaaaacaatt atttttctta
     3001 tgaaagatat agtttcttaa tggaggaaga gctgactgat tctttgtatg aagtacttaa
     3061 agtccaaggt accttagcca tcaatcctgg ggaaactgca cttgaaattg tcacagctga
     3121 tgaccaaatt gccaaaataa tggaagtagc tgttgggacg ccctttttct ttatggatac
     3181 tttaatcaac gatcaaaaca acataccaat tcatgtaggt aatcaatatt acctgggaga
     3241 agtatatcgt ttttacttat gatttcctgt ttggatttca aggagtagat tttatttatg
     3301 aagcaaatat tgcggtcaaa aatgattttt gatggagagc agccaccttt caaaggttat
     3361 attgtaatca atgaagggat cattgaaaag gtggaaaaca actggaatta cagtgatcta
     3421 ttaaatgaaa acacggaatt aattgcttat gatgatcaat tcgttatgcc agcaattcat
     3481 gataatcatg tatttttcag tggttatttg gctatgaatg ctggcataga tttaagcgat
     3541 acatcttcag ctaacgaggc tgtagagcgt attaaagctg taatgaacca taaaaaagca
     3601 gatgaaccaa tttatgctca tggctgggat gctgccctgt ggaaaactga cccatcagaa
     3661 gagctattga atgaaataaa ccactttggt ccaatcacag cgatcgacaa aaatcgcagc
     3721 cattgttgga tgaatgctat tgctaagcag acttatggtt ttacagaaaa agaaaccagt
     3781 gctgaaagtc gagtattatt aattaaggaa atgctagcaa acaaaaagct tttagcagag
     3841 gtttacgctg aatttgaagc attactgctt tcaaaaggtg ttatatcaat gaaagaaatc
     3901 gtttttgatg acgcagaatt tctttctaat atacctcaga ggaaaatact tagtaaccta
     3961 tatgtgcagg cagtccaaga acctctacag catgaacttc tatatgagta taaggaaaaa
     4021 gttttccctg aaaaggtccg ctttggtgga gtgaagatca tggtagatgg tgttgttgcg
     4081 gatagaagtg gagatattta cggtgtttat cagtcaggag tagcttcacc cgagattgac
     4141 tatgaggcaa ttaaagcaga agttgctgca ttcaatgaag tagagattcc ttgctgtttg
     4201 acaacggaag gagataaagc gggttataaa gctgcgtcaa ttcttgtcga atttggaaag
     4261 cggttacctg aaggcgtttt taattcgatt agtgatttgg aaatggttac tcaaaagaca
     4321 gcagaaaaaa tgaacgaagg acaagtagta gcagaggtat atccacaaat tctcggcttg
     4381 aatcaaacgt tagaagaggc ttacatgtca actgttataa aaaat
//
LOCUS       DACDAF010000134         4230 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.140, whole genome shotgun sequence.
ACCESSION   DACDAF010000134 DACDAF010000000
VERSION     DACDAF010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4230
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.140"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            56..478
                     /locus_tag="IVZ69_002620"
     CDS             56..478
                     /locus_tag="IVZ69_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184638.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAEERVE
                     GKIKSNQTKKYSSKLKKPVNESVHTRVDPFDPTKILKR"
     gene            497..2089
                     /locus_tag="IVZ69_002621"
     CDS             497..2089
                     /locus_tag="IVZ69_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184639.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEMERRTPEE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVISHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEIENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPEKRSEWNYGDENRTKLSPFTRGKLDELTKYVLTKEPGYQEYIQ
                     ISKALKEEAKSLYGESKRETKNAEKNALFDLKKRTGNAILTELKRQDSQIKPLIESVN
                     QMQSIYNERSFRTLKQLPTNEYKYSYQEFVKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            2101..2436
                     /locus_tag="IVZ69_002622"
     CDS             2101..2436
                     /locus_tag="IVZ69_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184640.1"
                     /translation="MKQYLDQWKVIEGSLKEERIEQLPDCLEKEHLFQISEMLRNEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEINEEGINNFPCESI
                     EESISLTEC"
     gene            2583..2777
                     /locus_tag="IVZ69_002623"
     CDS             2583..2777
                     /locus_tag="IVZ69_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184641.1"
                     /translation="MTQTTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQNGNI
                     LTLNLTTKMFVDAVENYPFV"
     gene            2809..>4230
                     /locus_tag="IVZ69_002624"
     CDS             2809..>4230
                     /locus_tag="IVZ69_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184642.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNNQFQKLFDHQKLTNGQ
                     PMNDKRNGRSWFNQQEKIENKIQSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKEKDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNHPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSSEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKK"
BASE COUNT         1735 a          635 c          860 g         1000 t
ORIGIN      
        1 tgttaattga ataataaaaa tagtattgtg aatttataaa aggaggaaat caattttggc
       61 aaaagcaaca agaaaacatg tatatcttta cgatatgcat atcgaagtac ttgatgaaat
      121 aatttctact catgaagata tatctaatta tagtgaagca gtcagacatt tgtgtatgat
      181 gtatgatcca aaaatcgaag aaaaaataaa tccaattcaa attaaattga atgcaatggg
      241 aaaagaaatt tctattttaa ccgaaatggt ttcagagttt gcggatcttc atttgaaaga
      301 tacaggaata ctaattggta caaattcaac tgtttatcaa gaagcagaag aacgtgtgga
      361 aggaaaaatt aaatccaatc aaaccaaaaa atattcttct aagttaaaga aaccagtgaa
      421 tgaatctgtt cataccagag tagatccatt tgatccaacg aagattctaa aaagataaaa
      481 gtagaaggag aacgtgatga ataaatcgcc tgcagttatt cttacttgtc aatttacctt
      541 gcccaataaa aaatcttttt caacatacat tgattatatg acaagagaaa aagcactgga
      601 agaaatggaa cgacgtacgc ccgaagaaga acaggaactg caacgaatca agaatgcttt
      661 agaggatttt tatattcctg aaggagaaac tttttcggaa agtaagacgg ataaagaatt
      721 cagtgaaacg tcgaatgaag ctcaatcgtt gatggaacat ggaatcaatt ttgacaagtt
      781 agaggaacaa gattttacca aatatctttc ttatatgacc cgtcactatg cgttagaaca
      841 aaagaaagaa ctgacgcaaa gggaacaaaa agaataccaa cggttgaacc aagcaatgaa
      901 aaaatatcaa acagagccac ataaaaaagc ttcaggaaat cttcctggag ttttttctat
      961 ggcttcagac gaagtgaaag gaagtgatct gaaggagatc aaacaaatct tccaaagagg
     1021 acaacaaaaa ggctcaatca tttatcaaga tgttatctct cacgacaatt cgtatcttga
     1081 aaaaatgggc ttgtacgatc ccaaaacaga taccttagat gaagaaggtt tgaaagcagc
     1141 tggaagaaaa atgatggaga cattattcga gaaagaacaa ttgaatgaaa caggttactg
     1201 gatggcaacg attcaccgta acactaagca tatccatatt cattttgcag ttgttgaaaa
     1261 agaaaatacg cgtaaaccgt atactgagat tgaaaatggt gtgagttata tcgtaccgaa
     1321 ggggaagaga agacaagcaa cattagacgc aatgaaaacc aattatgtac atgagttaga
     1381 acgtttctct tatgaaaagg atcgaatgat cggtatggag aaacgaaatt tattgacacg
     1441 aaaaagtgat ttgcgtaaca ccttaacaaa agtagtaaaa gaaccagcac gttacgatcg
     1501 acacgccatg aacttattaa atgaagtata taaaacccta cctgaaaaac gttcggaatg
     1561 gaattatgga gatgaaaatc gaaccaagct ttcaccattt acaaggggaa aacttgatga
     1621 gttaaccaaa tatgttttaa caaaagaacc tggatatcaa gaatatatac agatttcaaa
     1681 agcattgaaa gaagaagcca aaagccttta tggggaaagc aaaagagaaa caaagaatgc
     1741 agaaaaaaac gccctctttg atttaaaaaa gcgcacagga aatgcgattt taacagaact
     1801 gaagagacag gatagtcaaa taaaaccatt aatagaaagt gtcaatcaga tgcaatctat
     1861 ttacaatgaa cgatcctttc gaacactcaa acagttgcca acaaatgaat acaagtatag
     1921 ttatcaagaa ttcgtaaagc gtaggaaaca attccaacaa agagttgtca cgcagcgaag
     1981 cttgcgtcaa ttaaatcgaa caattaatgc acatgaagaa aaataccacg caagtaaagc
     2041 atatgaagag caacagcgaa gaatccaaat ggaacaagaa agacaatagg aggaagagaa
     2101 atgaaacaat atttagatca atggaaagtc atagaaggat cactaaaaga agaacgaatc
     2161 gaacaacttc ctgattgttt agaaaaagag catttgtttc agataagcga aatgttgaga
     2221 aacgaacagt ttgatccaaa tcaattttta gttgttgagt acccagctac tggtgtgtat
     2281 tgttgtaatc atgtgaaggg tgaaaaatat tttattattc aagaatacga aggtaagtta
     2341 gcgccttatt atactacttg ggaaataaat gaagagggaa tcaataattt cccatgtgaa
     2401 agcattgaag agtctatttc tctcacggaa tgttaaataa atagagacgt aaaagagtcc
     2461 tgaacgtgat tgtccaggac tctttttcaa tgaattgttt tccgccaatt cactgagtgg
     2521 tgcgattcaa ttttattata tcaaaagaaa gtgagattcc aaagtgaagg gaggaagaag
     2581 aaatgactca gacaacgatt ggtgttgtgg ttgaaaaaag cagggataat ctcgtttttg
     2641 tgacagaaat tcaaacaggt agagcttttg tagtcacaga caaagctgca aaagcgtatc
     2701 aaaatggcaa tattttaacg ttaaatctga ctacgaagat gttcgttgat gcagtagaaa
     2761 attatccatt tgtttagaca aacgatattt tacaaggagg aaacggacat ggcagaagaa
     2821 aaagaaccac tagataatag tcggttggga aagtccaaaa gaaaattagt acggttgcaa
     2881 aacgaattaa ataatcaatt tcaaaagcta tttgatcacc aaaaattgac aaatgggcaa
     2941 ccaatgaatg acaaacgaaa tggtcgttca tggtttaacc agcaagaaaa aatagaaaat
     3001 aaaatacaaa gtttgagaga agagatcaag caacaagaaa aacaggtaga aaaacttgaa
     3061 agacaagaag agctaaagga aatgggctat aacaagtacg gcggactgga tatgacgatc
     3121 gataatattc caagaatcaa agaagaaatc gaacgctttg aaaaaggtga atcgactttt
     3181 tcagccgcca cgatccgaaa atatcaacgg aagttggaaa cattagaaca gctgaaagaa
     3241 aaatcagaaa aaggaaaaga aaatatcctc cctgaagtac aagcgatcat tgacagcgga
     3301 cgagtgacgc aatggaaaaa aaatccaacc atttattttt tgaaaggcta tcgaaaagtt
     3361 gctttagaac tgaatgaaaa cgggggattt gaggaatcaa aaaaatacca agccacgtcg
     3421 gaagaggaaa aagcagctgt tcgtgaatta cttgaagagg ctgcaccaac tgattctctg
     3481 aaggagaaag aaaaagatca tttctatcga gtagaattca acgaaaatga tccagaaaaa
     3541 ggattgaaaa gttatggtgg ggagatcgta acattagaat tgatcgatca acttaaaacg
     3601 ttggataacc aatacgctgc agaagcaggt tattataaat tctattttga agaagtgaag
     3661 aacggagaag tagtagatca gatccgaatg gatctagggg atggcgtcaa cagtaatcac
     3721 cccatctatt tagagttagc aaaattgtgc gaacaagtac ctgagaagga acaaaaacaa
     3781 tcggtcaaaa atgaacctgt ttcgaaagaa caaatgcagt cgaaagaaac aaaaacaaaa
     3841 caaaagggct atcaaaaacg aacggcagaa gagatcaaac aagaagttaa atccctttcg
     3901 caacaggcac tggatgcggt gaaaaagcat acccattctt ctgaagacgt caaagaactt
     3961 ttgaacttta tgtctcgttt tccagaacga tcctttagaa atcaattatt gattgaggaa
     4021 caatttccag gtgcaacggc ttgtttaggt cgtgccgcgt tgaaaaaaga aggaatctat
     4081 atcaaaaaag gggaacaagg gaacaagatc tttgtcagaa aaacggtcaa aggattttat
     4141 gagaaaggac gtggctttgt tcgagaaaca gaagctacac cagaagataa aaaacgaatc
     4201 gaaagtggtc aaatcgaagt gatcaaaaaa
//
LOCUS       DACDAF010000135         4139 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.141, whole genome shotgun sequence.
ACCESSION   DACDAF010000135 DACDAF010000000
VERSION     DACDAF010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.141"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..171
                     /locus_tag="IVZ69_002625"
     CDS             <1..171
                     /locus_tag="IVZ69_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP8184643.1"
                     /translation="SLFPLYHGSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFK
                     IEYTKKRQRLAY"
     gene            346..642
                     /locus_tag="IVZ69_002626"
     CDS             346..642
                     /locus_tag="IVZ69_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184644.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            649..2601
                     /locus_tag="IVZ69_002627"
     CDS             649..2601
                     /locus_tag="IVZ69_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAP8184645.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="IVZ69_002628"
     CDS             complement(2673..3170)
                     /gene="dfrG"
                     /locus_tag="IVZ69_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAP8184646.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            3400..>4139
                     /locus_tag="IVZ69_002629"
     CDS             3400..>4139
                     /locus_tag="IVZ69_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP8184647.1"
                     /translation="MKYILSFCTPKLNYLLAYIRLYSGVLHLRDSVRVSEKEKIKVTE
                     MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRKKIENPHPLLQTTVE
                     PSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQMEVISALLQEKYHV
                     EIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLG
                     YLNQSFQNAVMEGIRYGCEQGLYGWNVT"
BASE COUNT         1454 a          672 c          738 g         1275 t
ORIGIN      
        1 tctctgttcc ctctttatca tggaagtgca aaaagtaata tagggattga taaccttata
       61 gaagttatta ctaataaatt ttattcatca acacatcgag gtccgtctga actttgcgga
      121 aatgttttca aaattgaata tacaaaaaaa agacaacgtc ttgcatatta agtagttcag
      181 ttttggagta caaaaagtga aaatgtaaac ctaaatgagt atcaaattgc aactgaattt
      241 gatactcgtt ttttattgtt aaatcaacgt ttgttgttaa tttacaccac aaaatgtaag
      301 ttaaaatgta tataaaaatg cgaacgtgaa ataattattg taggaatgca aattggtgtg
      361 ttaaaatggt tacaatttac taagcaaaaa ggggtgcatt ttcctatgca atttcttgag
      421 ccaaaaaata agaacgctaa gtctgtggat tgggaaatat cagagcaagt aagggtgata
      481 gttaagcaat acgctgaata tgcagagcgt actgaaagcg aagcagtgga tgaattctta
      541 ttgaacattt tagacgataa gaagtttatt gaatggattg ccaacaagcg aagtaataag
      601 cggattgttg aaaaaatggg tatcaaagat agagtgggtt gatagacaat gaccaagctt
      661 aaaagattag ccacgaagga agatgaaatt gtagatgtta aaattccgat ttcaaacgaa
      721 gaattaaaag atagggctaa acaatatgat ttattaactc caaaacgatt tgcaacaagg
      781 tataacaaaa tgttgttctt gccaacgtct tttaaatgga acggttctga atatcccatt
      841 caatataatt actgcatcaa tccgttttgt tgtaattttg ggaaagaaca gcacaaattc
      901 aaagatgtaa aagggaaacc aagtcgatat aaaatgactg gtagttccaa agataaaggt
      961 cataaaggta tgtactgcaa tgacaatcct attggcagag gtgtatcgca aaactgtaca
     1021 gtaacccctt tatctaattg gtctgttgtt gaagaaatta aacgccttat agaaatcaat
     1081 agcatccaag atgttgagcc agattatcaa tttcataaag aaggctgctc ggaagaagaa
     1141 tcaaccccat tcaatgagcc gaagcaattt tacaaaaggg ggaaaagtag gggcaaatct
     1201 caacgctatc aatgtaaggc gtgtaagaag ttcactaatg ttctaccaaa aagagaagaa
     1261 accactactt atcaccaaca aaagaacacc attcttccaa tgttcgctaa gatggttgtt
     1321 ggaagggttt cagtcagtcg tacttgtgat attttaggaa ttggagttgg aacctactat
     1381 cataagctgg agtggctgta taggcgttgt ttggagtttt tagaacgata tgagacacaa
     1441 ccccttcaaa caaagaaatt taacgagatg tggcttaata cggacaagat gcactactac
     1501 ctaaataacg tccgtaagaa aggacaaggt tcaaagaaat atacggggtt tgaagacctt
     1561 aatatgcaaa cgtatatagt tgtatctgct gaggtcttat caagatatgt gttccgttct
     1621 gatgttgcct atgattggaa tatttcaatg gatgaattaa atgaagatac aagaaaattc
     1681 aaagaagacc atctcaatac ttttagtcgt aaaaatgata ggttagattg gtcttattat
     1741 ccacaagaac catccgctaa cgatagcgaa aataggaatg cttatcttca cgaattaggg
     1801 aaaattacta ataggagtag atttgtcgat ggtttaaatg ttgatgctcc ttatactaca
     1861 actgctcact attggttaat taaacaaatg gttaatgccg acgaatggcg aatgattagt
     1921 gatgatgact tctctattag aaacgccttt tatagagtat tcacgaaaga attaaggttg
     1981 agcgatgcac atcattttat ttgccaagtt aacaagacga aaagcagaaa acaatgctta
     2041 aaagaattcg gacaagcaaa agcagaactg ctcgattggg gagatatcag aggattcaaa
     2101 acaaagtttc tacggacttt ggcatctcat tatctaactg aattactaac aagtcatcaa
     2161 ttccacgaag aggctattag taaagatgga gaaagatatc gcaaatatgc cgataaccct
     2221 atcaaacatc cattagccac taaggataaa ggattttatt cagttgattg tagaacggat
     2281 ttatctgctc tggaaccaaa cgaaatcgca aagatgctat taaatgttaa tgaccattcg
     2341 accaatagct ttattcaaca gataagacgt tatatatcat ctcttgaaag accattaaca
     2401 acagctcgtg gtgataagaa gagctatatt tacgctaact tcaatccgaa gtatgctcaa
     2461 tttgcgatta caattctaag aacttactac aacttttgtc gcccttttaa atcagcggat
     2521 aaaaaggttt tgacacctgc tcaaagatta gggattacag ataaacaatt tgattggaaa
     2581 gatataattt atttcaaatg acaaaaagag cttggagtaa tcccaagctc ttgtgcttta
     2641 tctttactgt tcttcttcaa ttaacgcacc cgttaactca ataagttttt tctttcatat
     2701 acatgaaaat agtagttata cggattttta tcattcttta tccctttttg ggcaaatacc
     2761 tcattccatt cctcataatt cacttctgga aaaaaagtat ctccttcgaa ttcatgatgt
     2821 atttttgtga tgtacatttt ctcaacataa gggaaaaaca aattataaat ctgttctcct
     2881 ccgaaaataa aaatttcttc ttcgttttta cataactcaa aaacatcttc tattgaatga
     2941 acaatttcac aaccattaaa ggtaaacccc ttatctctcg tcagaataat atttcttctg
     3001 tcaggtaagg ctcttccgat tgattcaagg ttcttcctac ctaatattat cggatgtccc
     3061 tttgtagtat ttttaacata ttcccagtcc ttgggaatcc tccaaggaat gtcattctct
     3121 ttgccaatca ctctattctt atccatcgca gcaatcaaag aaactttcat ttataacaca
     3181 gcctttttaa ctaatttacc atctaatttc ttatttctat caaaaaacct tttctcatta
     3241 tcctgcccgt tagttgaata agcaattttt tctataagtt atattatcat aataccacaa
     3301 aatcacaaat tttcattcaa ttatcatttt caattgcatt ttataaatca ttttgtatgt
     3361 aatttggtat gtaagttaaa atgaaaaaag tagtccattt tgaagtacat tttgtcattt
     3421 tgtactccaa aactgaacta cttacttgca tatatacgcc tttatagtgg agtactacat
     3481 ttacgagatt cggttagagt atcagaaaaa gaaaaaataa aagttacaga aatgtatact
     3541 tcaataaatg gtgaattatg taagattgat agagcttatt ctggagaaat tgttattttg
     3601 caaaatgagt ttttgaagtt aaatagtgtt cttggagata caaaactatt gccacagaga
     3661 aaaaagattg aaaatccgca ccctctacta caaacaactg ttgaaccgag taaacctgaa
     3721 cagagagaaa tgttgcttga tgcccttttg gaaatctcag atagtgatcc gcttctacga
     3781 tattacgtgg attctacgac acatgaaatt atactttctt tcttagggaa agtacaaatg
     3841 gaagtgatta gtgcactgtt gcaagaaaag tatcatgtgg agatagaact aaaagagcct
     3901 acagtcattt atatggagag accgttaaaa aatgcagaat ataccattca catcgaagtg
     3961 ccgccaaatc ctttctgggc ttccattggt ttatctgtat caccgcttcc gttgggaagt
     4021 ggaatgcagt atgagagctc ggtttctctt ggatacttaa atcaatcatt tcaaaatgca
     4081 gttatggaag ggatacgcta tggttgcgaa caaggattat atggttggaa tgtgacgga
//
LOCUS       DACDAF010000136         3763 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.144, whole genome shotgun sequence.
ACCESSION   DACDAF010000136 DACDAF010000000
VERSION     DACDAF010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.144"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..523
                     /locus_tag="IVZ69_002630"
     CDS             <1..523
                     /locus_tag="IVZ69_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184648.1"
                     /translation="EKAIPYIAAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTIS
                     NEINQYREREPEIQPAEVKQEHKNTVETAEQKNIVPVGSLWIDKKDGKVMEEDTGRTL
                     HLKDAAFIEDPQHNQVILKGKSYGKEIQTALPSEEFALGNSFRFSLETVSEVAKRKNE
                     IYYEQQLSQKERV"
     gene            584..2053
                     /locus_tag="IVZ69_002631"
     CDS             584..2053
                     /locus_tag="IVZ69_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3991 domain-containing protein"
                     /protein_id="HAP8184649.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKHERQNF
                     LVGDDRLDHAVAFLWKDPQTGETVGASYQGTIVDFNRFGKRGTYKHIDKNPTPNHGFN
                     LKIGDPKHLKFFESSIDLLSYAALNREKLQDAWLVSMDGLKHHVISHYVEESISELRR
                     KQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDPFTNKKIRCERGIPNDWQVPKEYKAT
                     YEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVSAHDVQSTFGKMLAKGEPVETIDLKE
                     ACTTVAKELKVCERADGTYNFDRFYSRKANIKDVNAGILLSYKAEQYYKGYKKHEHEF
                     VPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            2064..>3763
                     /gene="topB"
                     /locus_tag="IVZ69_002632"
     CDS             2064..>3763
                     /gene="topB"
                     /locus_tag="IVZ69_002632"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HAP8184650.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTAAAFEQ
                     LSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIEKVPLDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVEKEPLLT
                     "
BASE COUNT         1392 a          638 c          832 g          901 t
ORIGIN      
        1 ggagaaagct attccttata ttgcagcatg gacgaagaat ggtcagacgt tggatgataa
       61 ggaagctgcg gaacgtggga aaatcatgaa tgatgtcagc cgtgtcgcaa atgaattcat
      121 tcaaaccatt tctaatgaaa tcaatcaata cagagaaaga gaaccagaga tccaaccagc
      181 agaagtgaag caggagcata aaaatactgt agaaacggca gaacaaaaga atattgttcc
      241 tgttggttca ctttggatcg acaagaaaga cgggaaagta atggaagaag atacgggtcg
      301 aacgttacat ttgaaggatg cggcgtttat tgaagatcca cagcataatc aagtaatttt
      361 aaaaggaaaa agttatggaa aagagatcca aacggcgtta ccttcagaag aatttgcgct
      421 aggaaattca ttccgatttt cacttgagac agtgtcagaa gtggcaaaac gaaaaaatga
      481 aatctattat gaacaacaat tgtcacaaaa agaacgtgta taaaacaagt aaaaaagact
      541 atctgaaaaa cggatagtct tttttctttt gggaggtttt aaaatgaccg agaaaaaaat
      601 gagtcttatt gatcgatgta aacagatcga tatagtggat tttgctcgaa acaatggaat
      661 ggctgtagtc aataaaggac gagactatcg cttagaagac catgattcat ttgtttttga
      721 tcgaagaaaa caacgttttt attggaacag tcaaaatatt agtggcgaca ttattgaatt
      781 agctaaactt tttttcatag acaaagagat ccaagaccct aagcaacaat ttaaagcagc
      841 cactgatttt attctaaaga atgaagacaa aacagaacga gtggaaaatc ttcattttga
      901 gacagaaaag tacaaagatc accccgttga ttatcaacca ctcacagaaa aaggaaggaa
      961 ttatctgaag gaagaacgaa aactaccaga gtggctgatt gattatgcag aaaaagaagg
     1021 gttgattgct gaactaaagc cgaaacatga acggcaaaat tttttagttg gagacgaccg
     1081 tttagatcat gcggttgctt ttttatggaa agatccacag acaggagaga cagtaggggc
     1141 aagttatcaa ggaacgatcg tcgattttaa tcgtttcggt aaacggggaa cgtataaaca
     1201 cattgacaag aatcctacgc caaatcacgg atttaattta aaaataggcg atccgaagca
     1261 tttaaaattc tttgaaagta gtattgatct gttaagttac gctgcattga atcgggagaa
     1321 actacaagat gcctggttag tttcgatgga cgggttaaaa catcatgtaa tcagtcatta
     1381 cgttgaagag tcgatttctg aattaagacg aaaacaaaca tttcctcaat cgattgaaat
     1441 atgtgtggac aatgatcgtg caggacatat tttttatgaa aaagaacaga tgaagggaat
     1501 cgttgatcct tttaccaata agaaaatccg ttgtgagcga ggaattccaa atgattggca
     1561 agtacctaaa gaatacaaag ctacttatga agcagtcgca aaagaaatga gtgttgaacc
     1621 tgaagcaatt atggccatac acaaaactga aactaattta cagctgacaa atcaattggt
     1681 gtctgctcat gatgttcaat ctacgtttgg aaagatgttg gcgaagggcg aaccagtaga
     1741 aacaattgat ttgaaagaag catgtaccac ggtcgcgaag gaactgaaag tatgtgaacg
     1801 cgcagatgga acatacaact ttgatcgttt ttatagtaga aaagccaaca taaaagacgt
     1861 taatgcagga atccttcttt cctataaagc agaacaatac tacaaaggct ataaaaagca
     1921 tgaacatgaa tttgtacctg aagtgaaaaa ggattggaat gatcaattga agcatgagat
     1981 ccagcaacaa gaaatcagaa agcaaaaacg tgcgatgttg tttcaacaag gcagacaaca
     2041 agaaagggag tgaagtcgtc actatgaaaa ccgtcatttt agcagaaaaa ccgtcacaag
     2101 cgaaggctta tgccgatagc ttttctaaag ctacccgaaa agatgggtat tttgagatcc
     2161 aagatcgatt gtttacagga gaaactgtga tcacgtatgg ttttggtcat ttagtcgagt
     2221 tagattcgcc cgatatgtac gatgaaaaat ggaaacaatg ggcattagaa catttgccta
     2281 ttttccccaa tcaataccac tatcatgttc ctaaagataa gaaaaagcag tttagtgtcg
     2341 tcaaacgaca gctgcagtca gctgatacga ttgtgatcgc gactgatagc gatcgtgaag
     2401 gggagctgat tgcctggtca atcattcaac aagcaggcgc caatcaagga aaaaccttta
     2461 aaagactttg gatcaactcc ttagaaaaag aagccattta tcagggattc caacagttac
     2521 gagacgcaga agagacctat ccaaaatttg aagaagtaca agcacgtcag atcgccgatt
     2581 ggttaattgg gatgaacggt agcccactgt atagtttact cttgcagcaa aaaggcatac
     2641 caggaagttt ttctttaggt agagtccaaa ccccaacact ctatatgatt tatcaattgc
     2701 aggaaaagat tagaaacttc caaaaagaac catattttga aggaaaagcc caagtaatcg
     2761 ctcaaaatgg cgcatttgat gcgaagcttg atccaaatga aacccaagcg acacaagaag
     2821 catttgaagc ctatttaaaa gaaaaaggtg ttcaattagg aaaacagcca ggtacgatcc
     2881 ttcaagtcga aacagagaaa aaaagtgcgg ctagcccacg tcttttttct ttatcgagcc
     2941 ttcagtctaa aatgaatcaa ctcatgaaag ctagtgccaa agatactttg gaagccatgc
     3001 aagggttgta tgaaggaaaa tatctaagct atccgcgaac ggatacccct tatattacgg
     3061 aaggggaata tgcgtatctg ttggatcact tagacgaata caagcatttt ttaaaagccg
     3121 aagcgattcc gactcctatt catacaccga atagtcggta tgtgaataat aagaaagtcc
     3181 aggaacatta cgcgatcatt cctacaaaaa cggttatgac agcagcggct tttgaacaac
     3241 taagtccact gcagcaggct atttatgaac aagtgttaaa aacaacggtg gccatgtttg
     3301 cggaaaagta tacctatgaa gaaacaacga tcttgacgca agttcagcag cttcagttaa
     3361 aggcaatcga aaaggtgccg ctagatctag gttggaagaa gttatttgga aaagagagcg
     3421 acggaaaaga gaaggaagaa gagccgctac ttcctaaagt gacaaaagga gaaatggtga
     3481 cggtggatct acaagttctt gaaaaagaaa ccaagccacc acaaccttat accgaaggta
     3541 cgttgatcac tgcaatgaaa acagctggga aaaccgtgga tagtgaagaa gcgcaatcca
     3601 tattgaaaga agtggaagga atcggtacag aagcgacacg ggcgaatatt attgaaacct
     3661 tgaaacaaaa ggaatatatc aaggtagaga aaaataagct cgtggtgacg aataaaggga
     3721 ttttgctttg ccaagccgtg gaaaaagagc cgctgcttac gag
//
LOCUS       DACDAF010000137         3665 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.145, whole genome shotgun sequence.
ACCESSION   DACDAF010000137 DACDAF010000000
VERSION     DACDAF010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.145"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..278
                     /locus_tag="IVZ69_002633"
     CDS             <1..278
                     /locus_tag="IVZ69_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific recombinase"
                     /protein_id="HAP8184651.1"
                     /translation="ELIKLANKGQDYEHLADEIDELRDKRQLLLVEDASLSGENERIN
                     ELIEFIRKNKFRTLEYDDKLVRKIIQSVTVYEEHFVISFKSGIEMEI"
     gene            421..642
                     /locus_tag="IVZ69_002634"
     CDS             421..642
                     /locus_tag="IVZ69_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014315041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184652.1"
                     /translation="MTTAEMIKELCEQMNISVSELARRIGQTPQNFNKKLQRETVTLD
                     ELKAIADVLGVKFVQAFILPDGNEIKIGN"
     gene            658..1500
                     /locus_tag="IVZ69_002635"
     CDS             658..1500
                     /locus_tag="IVZ69_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184653.1"
                     /translation="MKIITINDVEYAVFAANEGTSKPQPHIIETKSGTIPEGKQLSLL
                     KEYLKQNDISPIKGATTYWCIDKVLKLDSSKEKTISETIHKQKYLSLTEENIEKQHKF
                     VGASSNYGKEGLIIHDVLNAFPLHNDLNTIAMKIAVIDVTNSTHLSQYKSRLSLYDLA
                     KVILEIPNFDDRLAKGDPQLINIIARNIGAVNMFSFASKYCTYHNVEVCGRDDYSIFD
                     GIVKNTLPHYIQGLTTNKIDTWRRSFDYEAFNECVGKLLDENNIHIPFRRRKLDHFLW
                     YANR"
     gene            1563..3365
                     /locus_tag="IVZ69_002636"
     CDS             1563..3365
                     /locus_tag="IVZ69_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HAP8184654.1"
                     /translation="MGLFDFLKKKQGKVSKHVDYQLASSLFRTGKVFAEKLEVDISNV
                     DEFRKTFIAFDVETTGLNSSSDRIVEIGAVLFKEGVPIQSFGTLVNPKVRIAASASAI
                     NNITNEMLNSAPNEQEVYPQLVEFLGDALDGKITMCAHNASFDFGFLSNTFSRLGYDA
                     KIKYVDTLSLSRKHIKGIVNHKQETVAEYFGLINDTAHRAESDADICGKIFWGVLDII
                     EESLEEQKKQIEKMTPDIKELEACAFIQDIIEKKGCDTSWIRYRKNSNNYVDVTCLYT
                     FLKFKFAKKGNYIIIRKDATNGIDLPIEPCTVSEGGTTNVRVYFRSPFDLTPLSNYIF
                     SAYSDCYNSMNEYMSVSNYTKKEAEQSLSMLKSISKSAMKELLFDAKNRGYDETEVNL
                     NIEKVISREDVIINGLHNRVSLNKIRNIGNWEKGFDAGYPYWERGETARKNGKVDEAI
                     ALFDKARYNGYDAPALYDSYAKAYRKIKDYDNEILILDEGIMRKTRHDVGTLEARRDK
                     AIKLLFAKQEAERIAKEKSDFLKANKKEDAISEPSKKRGRQIIQMTDDGTIIKEFDTI
                     ASAVKEVGVNSKSIRDAANGVQKHAGGYYWKYKD"
     gene            complement(3424..>3665)
                     /locus_tag="IVZ69_002637"
     CDS             complement(3424..>3665)
                     /locus_tag="IVZ69_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS982 family transposase"
                     /protein_id="HAP8184655.1"
                     /translation="PPRKNMDKSEKLDHSLLGKQRKTVGTVFSSLEKLGCQNFNSRSV
                     KGLESRFESILLAYSVLLSRAQRRFEGTLRYSLGY"
BASE COUNT         1308 a          519 c          746 g         1092 t
ORIGIN      
        1 aagaactcat caagctggct aataagggtc aagattatga acatctagca gatgagattg
       61 atgagctgag agacaagcga cagctccttt tagtagaaga tgcctccctc agtggcgaga
      121 acgagcgaat caatgagctg attgaattta tccgcaagaa caaattccgt accttagagt
      181 acgatgataa gcttgtaagg aagataatcc agagcgttac agtctatgaa gaacacttcg
      241 tcatatcctt caaatctggc atcgaaatgg aaatatgaaa accagaagta aatagcccat
      301 gattctacag tagagtcgtg ggttttcttt tgcttgctga ttataataat attttaataa
      361 ctattgttat tataaaccaa atgatttata atattcttag cgtaaacttg gaggtgctgt
      421 atgactacgg cagaaatgat taaagaactg tgtgagcaaa tgaatataag tgtttccgaa
      481 cttgctagac gtattggaca gactccacag aatttcaata agaaattaca acgagaaacg
      541 gtaaccttag atgagttgaa agcgattgct gatgtgctag gtgtcaagtt tgtgcaggct
      601 tttatattgc ctgatggcaa tgaaataaag ataggtaatt aggaggtgta atttgtattg
      661 aaaatcataa caataaatga tgttgagtat gctgtatttg ctgctaatga aggtacttcc
      721 aaaccacaac ctcatatcat agaaacgaaa tctggtacta ttccagaagg aaaacaactg
      781 agtttattaa aagaatatct taagcagaat gatatttccc caataaaagg agcaacaaca
      841 tattggtgca ttgacaaggt tcttaagctt gattcaagta aagaaaaaac tataagtgaa
      901 acaatccata aacaaaaata cttatcttta actgaagaaa atattgagaa acagcataag
      961 tttgtaggtg caagctctaa ttatgggaaa gaaggtctaa taatacatga tgttttgaat
     1021 gcatttcctc ttcataatga tttaaatact attgcgatga agattgcggt aattgatgta
     1081 acaaattcaa cacatctttc tcaatataag agcaggttgt ctctatatga tttggctaaa
     1141 gtaattctgg agattccaaa ttttgatgat cggttggcaa aaggagatcc tcagttgata
     1201 aatattatcg caaggaacat tggtgcagtt aatatgttct catttgcatc caagtactgt
     1261 acatatcata atgtggaagt gtgtgggaga gatgattact ccatctttga tggtatcgtt
     1321 aaaaatactc ttccacacta tatccaagga ctaactacga ataagattga tacgtggcga
     1381 agaagttttg attacgaggc atttaacgaa tgtgttggaa aactacttga tgaaaataat
     1441 atacatattc cttttagaag aagaaagtta gatcacttct tgtggtatgc gaataggtag
     1501 aatataagaa aaaggcatcg taaaagtgat tctggataaa attaatgggg gaggaaataa
     1561 tagtgggatt atttgatttt ctaaagaaaa aacaaggaaa ggttagtaaa cacgttgatt
     1621 atcaactggc ttctagtcta tttcgtactg gtaaagtttt tgctgaaaaa ttggaagtgg
     1681 acatatcaaa tgtagatgag tttcgtaaaa cttttatcgc ttttgatgtg gaaacaactg
     1741 gcctaaattc ttcttcagat agaattgtag agattggtgc ggtgctattt aaagaaggag
     1801 ttccaattca atcattcgga actcttgtca atccaaaagt tagaattgca gcctcagctt
     1861 cggcaataaa taatataact aatgaaatgc taaactctgc tccaaatgag caggaagttt
     1921 acccccagtt ggtagaattt ttaggagatg cactagatgg aaaaatcact atgtgtgcac
     1981 acaatgcaag tttcgatttt ggatttttaa gtaacacatt ttctagactt gggtatgatg
     2041 ctaaaattaa gtatgttgat actctgagtc tctctagaaa acatataaaa ggcattgtaa
     2101 atcataagca agagactgta gcggaatatt tcggattaat aaatgacact gcccatagag
     2161 cggaatcaga tgcagatata tgcggaaaga ttttttgggg tgttttagat attattgagg
     2221 agtcgttgga agaacaaaaa aagcaaatag aaaagatgac tccagacata aaagaacttg
     2281 aagcttgtgc ttttattcaa gatattattg agaaaaaagg atgcgacacc agttggatca
     2341 ggtatcgaaa aaacagtaat aattatgtcg atgtaacttg tctatataca ttcttaaagt
     2401 ttaagtttgc taagaaggga aattacatca ttattagaaa agatgctaca aatggaattg
     2461 atttacctat agaaccttgt actgtaagtg aaggcggtac aacaaatgtg cgagtctatt
     2521 ttcgtagccc ctttgactta acgcctcttt caaattatat tttcagtgct tatagcgatt
     2581 gttataattc tatgaatgaa tatatgagtg ttagtaatta cactaaaaaa gaagcagagc
     2641 aaagccttag tatgctgaaa tctatttcaa aatcagcgat gaaagagtta ttattcgatg
     2701 caaaaaatcg tggatatgat gagactgaag ttaacctaaa tattgaaaaa gtgatatcta
     2761 gagaagatgt aattattaac gggttgcata atcgagtttc attaaacaag atacgaaata
     2821 tagggaattg ggagaaagga tttgatgcag gttatccata ttgggaacgt ggagaaactg
     2881 ctaggaaaaa tggcaaagta gatgaagcta ttgcactttt tgataaagct cgatataacg
     2941 gctatgatgc tcctgcgcta tatgattctt atgctaaagc ttatcgaaaa attaaggatt
     3001 acgataatga aattctcatt cttgatgaag gaattatgcg taaaacacgg cacgatgttg
     3061 gtactttaga ggctcgtagg gataaggcaa ttaagctatt atttgctaaa caagaggcag
     3121 agcggatagc taaggaaaaa tctgattttc taaaagcgaa caaaaaagag gatgcgatta
     3181 gtgagcctag caagaagcgt ggaagacaga ttattcaaat gactgatgat ggaacaataa
     3241 taaaagaatt cgatactata gcttctgctg taaaagaagt tggcgttaac tcaaaaagta
     3301 ttagggatgc tgcaaatgga gttcaaaaac atgctggagg atactactgg aaatacaaag
     3361 attagcagat aatctaagat aacctaggat cttcttaata gatacccgtg gtgctagtta
     3421 attttaatat cctaaagaat atctcaaagt tccttcaaaa cgtcgttgtg ctcgacttaa
     3481 tagaacactg taagccagta atatgctttc aaatctactc tctagccctt taacagaacg
     3541 tgagttgaaa ttttgacaac ctaatttttc taaggaagaa aaaacagtcc caactgtttt
     3601 tctttgtttt ccaagtaagc tgtggtctag tttttctgat ttatccatgt ttttacgtgg
     3661 cggaa
//
LOCUS       DACDAF010000138         3648 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.146, whole genome shotgun sequence.
ACCESSION   DACDAF010000138 DACDAF010000000
VERSION     DACDAF010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3648
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.146"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            129..374
                     /locus_tag="IVZ69_002638"
     CDS             129..374
                     /locus_tag="IVZ69_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184656.1"
                     /translation="MSKSKKNITIIGLGLTVYLFTEFVYRHVNLFAEPLFVLYESNSS
                     IVSELANLMIALLFTPALRVITILVCLVLLFFVNKKK"
     gene            complement(558..1307)
                     /locus_tag="IVZ69_002639"
     CDS             complement(558..1307)
                     /locus_tag="IVZ69_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP8184657.1"
                     /translation="MLKLERHQKILDLLNAEQKVIASDLSQRFNVSEDTIRRDLKDLD
                     SQGLLKRVHSGALRVGPPITNFNYRETVASEQKTALAHKALPFLKEESVIIIDGSTTN
                     LALAKEIPQDFRATIITNSPPIAIALAQHPNLEIINIGGTFYKQSMINIGVQAYKQLQ
                     NIRADLYIMGIYNIDLDVGTSVPTMQESDIKREMIRISTEVLGMITNDKFGTISNHIV
                     GPIEDLTYLISEEIPEKVRKEYNKQKIVLID"
     gene            1493..2197
                     /locus_tag="IVZ69_002640"
     CDS             1493..2197
                     /locus_tag="IVZ69_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HAP8184658.1"
                     /translation="MEKKIILSPSLMCGDLANLEGSIQELESIGMDSLHIDVIDGSFS
                     PSMPLGIETIKRIREITSMNFDVHIMAKDNDNEFFIGEMLKIGVESITFHYETSLHID
                     RYIQLIKNSGTKVGIALNPATPLNVLQYILPEIDRICLMLINPGFATNKSEKQVSYAL
                     KKITDLCQLVNEKELAVDIQVDGRVSLETIPGLLDAGATNLVLGSTSLFLKGNTLAEN
                     QKLLYQAMKQSVRKNQ"
     gene            2237..2794
                     /locus_tag="IVZ69_002641"
     CDS             2237..2794
                     /locus_tag="IVZ69_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010758046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP8184659.1"
                     /translation="MSYKAAKQNIVREITETLDRISSKDVEQLIKKIEKAERVFFVGV
                     GRVLLALEGMAKRLGHLGIQTVVVGQITEPAITDKDLLIVGSGSGESAFPLTIAKKAK
                     EFGSQVAHIGSNPDSTMKEYSDLFIRIPVQTKLALPEEISSIQPMTSLFEQSVLLLGD
                     SIALVMIEEKAIDMSKLWQYHANLE"
     gene            2802..3206
                     /locus_tag="IVZ69_002642"
                     /pseudo
     CDS             2802..3206
                     /locus_tag="IVZ69_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330245.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
     gene            complement(3259..>3648)
                     /locus_tag="IVZ69_002643"
     CDS             complement(3259..>3648)
                     /locus_tag="IVZ69_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP8184660.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT         1212 a          531 c          707 g         1198 t
ORIGIN      
        1 aataatatca gttatcaaat ttcctgtaaa ttttcttgaa actacagcat attattactt
       61 caaaacaatc tacatttttt ataaaaaagg aaatgaataa ctgaaaaaat tattatagga
      121 gagaaaaaat gtcaaaatct aaaaaaaata tcaccataat tggtttaggc ttaaccgtat
      181 atttatttac agaatttgtt tatagacatg tgaatttatt tgcagaacct ttatttgtat
      241 tatacgaatc aaattcctca atcgtcagtg aacttgctaa tttaatgata gcattgctgt
      301 ttactcccgc gttgagagtc ataactattt tggtctgttt agtgctattg ttttttgtta
      361 ataaaaagaa ataacgtagt atttcaaaag acaaagaagt gggatgatga ttgctatagt
      421 atgttatacg tggtgctagg taagtgagaa taaacaaaaa aggaaacacg caataaagtt
      481 tatttcaaaa ctttattgcg tgtttctttt ttagattttt tatatctgtt gctttagtag
      541 ttaccaatag ttttcgctta atcaatcaaa acgatttttt gtttattgta ttctttacga
      601 accttttcag gaatttcttc tgaaataaga taggtaaggt cttcaattgg accgacgata
      661 tgattactga tggtgccgaa tttatcatta gttatcatcc caagtacttc agtagaaata
      721 cgtatcatct cacgtttaat gtcggattct tgcatagttg gcacgctcgt tccaacatct
      781 agatctatgt tataaatacc cataatataa aggtcggctc gaatgttttg tagttgctta
      841 taagcttgta ccccaatatt gatcatagat tgtttataaa aagtaccgcc aatattgata
      901 atttccaaat taggatgctg tgctaatgct atggcaatcg gcgggctatt ggtaatgatt
      961 gttgcacgaa aatcttgtgg gatttctttt gctaaagcca agttagttgt acttccatca
     1021 atgatgatga cagattcttc ttttaaaaaa gggagggctt tatgagctaa tgcagttttt
     1081 tgttcgctag ctacagtttc tcggtagtta aaattggtaa ttggcggacc aacacgtaaa
     1141 gcgccgctgt gtactctttt taagagacct tggctatcca aatctttcaa atctcgtcga
     1201 atcgtgtctt cggatacatt gaaacgttga cttaaatcac tagcgataac tttttgttct
     1261 gcgtttaata aatctagaat tttttgatga cgttctaatt tcaacatgtt gcgtgctcct
     1321 tcttatttat tcttgtttat catgtcattt atgcgttttt atgtcaataa tttccgtttt
     1381 taatacacta aaaaggcata aacaagcaaa aacaaaatat ttttatgcag ttttatgttg
     1441 actagtattt gttaagcggt tacaatgagg gggtaattaa aggagggaat gtatggagaa
     1501 aaaaattatt ttgtcgcctt cacttatgtg tggggatcta gcaaatttgg aaggaagcat
     1561 ccaagaacta gaaagtattg ggatggattc cttgcatatt gacgtgattg acggttcttt
     1621 tagtcccagt atgcctttag ggatcgaaac aatcaaaaga attagagaaa tcacttcaat
     1681 gaattttgat gtacacatca tggctaagga taacgataac gaatttttta ttggagaaat
     1741 gttgaaaatt ggcgtagaga gcattacttt tcattatgaa acaagcctcc atattgatcg
     1801 atatatccag ctcatcaaga attctggaac aaaagtaggg atagctttga atccagcaac
     1861 tccgttaaat gtattacaat atattttacc cgagattgat aggatttgtt tgatgctgat
     1921 taatccaggt tttgcaacaa acaagtcaga aaaacaagtt tcttacgcgc taaaaaaaat
     1981 tacagatctt tgccagttag taaatgagaa agagttagca gtagatatcc aagtggatgg
     2041 acgggtatcg ttagaaacga tcccgggatt attagatgca ggcgcaacaa atctggtatt
     2101 aggaagtaca agtttgtttc ttaaaggaaa tacattagca gaaaatcaaa aactacttta
     2161 tcaagcgatg aagcaatcag ttaggaaaaa tcaatagatg tagtggtcct gaataataga
     2221 aatggagggg aaatagttga gttataaggc ggcgaaacaa aatattgtaa gagaaattac
     2281 tgaaacatta gaccgtattt cttcaaaaga tgtggaacaa ttgataaaga aaattgaaaa
     2341 agcggaacga gtttttttcg tgggggttgg cagagtactg ttagcgctag aaggaatggc
     2401 aaaacgctta gggcatctag gaattcagac agtagtcgta ggacaaatca ctgaaccggc
     2461 aattacagat aaagatttat tgattgttgg ttctggtagt ggggaaagtg ctttcccact
     2521 aactattgca aaaaaagcaa aggaatttgg gtcccaagtt gcccatatag gatcaaaccc
     2581 agacagcaca atgaaagaat attcagatct ttttattcgt atacccgtac aaacaaaatt
     2641 agcgttacca gaggaaattt cttctataca gccaatgact agcctgtttg aacaaagtgt
     2701 tcttttgtta ggagatagta ttgctttagt gatgatagaa gaaaaagcaa ttgatatgtc
     2761 aaagttgtgg caataccatg ctaacttaga gtaggtgaaa aatgaaagcg gtacattttg
     2821 gagcagggaa catcggcaga gggcttattg gacaaattct acatcagaat ggattcgatc
     2881 tatgttttat tgatacgaat cctgaactga tccatcaatt aaatcaagat aagggttata
     2941 ctatcgaaat tattgatgaa atgaacagga gtgatttcat tgatcatgtt gtggcactga
     3001 atagtttatc cgagctagaa gaggtgatta cagcaacaaa aaatgcagat atcttaacaa
     3061 catctgttgg cgcaataaat ttagtaaaaa ttgcaccgat cattgcgcaa gccttaagta
     3121 agcgatttga acaaaagcat agcatcaata tcgtagctaa tgaaaatgtg ataaatgcaa
     3181 gtgatgtgtt gaaaaaagaa atttatggga gcgtcaataa ttttgtgtaa ataaattgtc
     3241 ctcctgcaaa ataattagtt actcagtaaa cattgaaact aatgtatcgg ttacctgttg
     3301 aaaaccttta tggcttctgt ttagaaattt ttgattgtat gtatcaaaaa tgctgactag
     3361 aaagcgttct agtgattctt cattttgaaa ctgctctttt ctacggctgt atcttttaat
     3421 ttgcttattg aaagactcga ttagattggt tgagtaaatg gttctacgaa tgctaggtgg
     3481 aaaatcataa aaagttaata agtcttggtt ttctatgagt gactgcgtca ctttaggata
     3541 gtttttcttc catttctcaa tcatgccgga taagaaggta ttcgcttctt cttttgagtt
     3601 agcttgataa acagccttaa agtcatcaca gatttctttt cggtcttt
//
LOCUS       DACDAF010000139         3458 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.147, whole genome shotgun sequence.
ACCESSION   DACDAF010000139 DACDAF010000000
VERSION     DACDAF010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3458
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.147"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            242..1024
                     /gene="rpsB"
                     /locus_tag="IVZ69_002644"
     CDS             242..1024
                     /gene="rpsB"
                     /locus_tag="IVZ69_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HAP8184661.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            1123..2004
                     /locus_tag="IVZ69_002645"
     CDS             1123..2004
                     /locus_tag="IVZ69_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HAP8184662.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            2140..2862
                     /locus_tag="IVZ69_002646"
     CDS             2140..2862
                     /locus_tag="IVZ69_002646"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010761216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HAP8184663.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            2865..3422
                     /gene="frr"
                     /locus_tag="IVZ69_002647"
     CDS             2865..3422
                     /gene="frr"
                     /locus_tag="IVZ69_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HAP8184664.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
BASE COUNT         1266 a          599 c          772 g          821 t
ORIGIN      
        1 caaagagaaa tctactgttt ttcttgaatt ctttttatct ttcaggtaaa ctattgaatg
       61 ttgagcagaa aagtatattt gctcttgcga tacggatctt ttgtctgtat aatagctgag
      121 ggtgctttat gcatcagcaa atccacattc ttattggatt gtcggtaggt gcttgaaaaa
      181 gtttgccggc aaggtagaag ataagaagag gaaaaataaa accaaatcgg aggaaacaaa
      241 catggcagta atttctatga aacaattact agaagccggc gtacactttg gtcaccaaac
      301 tcgtcgctgg aatccaaaaa tgaagaaata tatcttcaca gaaagaaacg gaatctacat
      361 cattgacttg caaaaaacag ttaaattagt agatgcagct tatgattaca tgaagagcgt
      421 tgctgaagaa ggcggcgtag cattattcgt aggtacaaaa aaacaagcac aagaagcaat
      481 caaagaagaa gcaactcgtg caggacaata cttcgttaac catcgttggt taggcggaac
      541 attgacaaac tgggatacta tccaaaaacg tatcagccgt ttgaaacaaa tcaatgcaat
      601 ggaagaagat ggaacttttg aagttctacc taaaaaagaa gttgctggtt tgaacaaaga
      661 acgtgaacgt cttgaaaaat tcttaggcgg tatcgctgat atgccaagaa tcccagatgt
      721 aatgtacatc gttgacccac gtaaagaacg tattgctgtt caagaagcac acaaattaaa
      781 tatcccaatc gtagctatgg ttgatacaaa ctgcgatcca gatgaaatcg acgtagtaat
      841 cccttcaaac gacgatgcaa ttcgtgccgt taaattgatt acttcaaaaa tggctgatgc
      901 tttcatcgaa ggaaaccaag gtgaagatca agtagttgaa gaagatttca cagaagaaaa
      961 cacagcaaca tcaatcgaag aaatcgtaga tgttgttgaa ggcgacaatt cttcagcaga
     1021 ataattttga atgatggagc tgtttcaaag gctgggcgac aagcctcact ctcctttgaa
     1081 gcagcttttt ttaaaaagaa aaacacacag gaggagttaa acatggcaga cgttacagct
     1141 aaaatggtaa aagaactacg cgaaatgact ggcgtaggaa tgatggatgc gaaaaaagca
     1201 ttagttgaag tagaaggcga catggaaaaa gcagttgatc ttttacgtga aaaaggaatg
     1261 gcaaaggctg cgaagaaaaa tgaccgcatt gcagctgaag gattggcttc agttgctgtg
     1321 aaaggtaaca ctgcagcaat cgttgaagta aactcagaaa cagactttgt ttctaaaaac
     1381 gaaatgttcc aagatttagt aaaagaaatt gcagaacttg ttgctgaaaa caaaccagca
     1441 gacatggaag ctgcaatgaa aatcaaaaca gataaaggta caattgaatc tgacttgatc
     1501 gaagcaactc aagttatcgg agaaaaaatc agcttccgtc gctttgaagt tgtagaaaaa
     1561 gacgacaatg ctgcatttgg tggatacttg catatgggcg gacgtattgc cgtattgact
     1621 gttctagatg gaacaactga cgaaacagtt gcaagagacg tagctatgca cgtagcagct
     1681 atcaatcctc gttatgtaaa cgaatcacaa attccagaag ctgaattaga acatgaaaaa
     1741 actgttctta cagaacaagc attgaacgaa ggcaaaccag cgaatatcgt tgaaaaaatg
     1801 gtagaaggac gcttgaagaa attcaaagca gaaatcgctt tggtggacca accattcgtt
     1861 aaagatcctg atatgactgt tgaaaaatac gttgcatcaa aaggcgcaac tgttaaaaca
     1921 ttcgtacgtt tcgaagttgg cgaaggtatc gaaaaacgcg aagataactt tgtagaagaa
     1981 gttatgagcc aagtgaaaaa ataattctgt tgaataacag acgggaacgc acggtttgtg
     2041 cgctcccttt ttttaagcaa aacaagaaaa accagtctta gagtgtcgaa atcatctaag
     2101 tatggtaaaa tggcaataga aaatattgga ggaatgaaca tggtcacacc gaaatatcag
     2161 cgtgtagtct taaaattgag tggagaagct ttagctgggg atgcaggatt tggaatcaaa
     2221 ccaccagtaa tcaaagaaat catccaagaa atcaaagaag ttcacgagct gggcgttgaa
     2281 atggcaatcg ttgtgggtgg cggaaatatc tggcgcggac aaatcggagc acaaatgggc
     2341 atggaacgtg ctcaagctga ttacatgggt atgttagcta cagttatgaa tgccttagct
     2401 ttacaggata cgttggaaaa cgtgggtgta ccgacacgcg tgcaaacttc gattgaaatg
     2461 cgtcaaatcg cagagccata tattcgccgt aaagcagaac gtcatttaga aaaaggacgg
     2521 atcgttatct ttgcaggcgg taccggcaac ccgtacttct cgacagacac aacagcagca
     2581 ttacgagcgg cagaaatcgg cgcagatgtt atcctgatgg ctaaaaacaa tgtagacggt
     2641 gtttattctg ctgatccgaa agtagatgca aatgcagtaa aatttgaaga actgactcat
     2701 ctggaagtta ttgccaaagg attacaagtc atggattcaa ctgcaagttc actaagcatg
     2761 gataatgata ttccactgct tgtcttcaat ttaaatgaac acggaaatat tcgccgtgca
     2821 atcttaggcg aaaatatcgg aacaactgta agggggaaat aaaaatggca gatgcaatta
     2881 tgacagaagc aaaagaaaaa atgaaaaaag cagcacaaaa tcttcaacgt gaacttgggc
     2941 aaatccgcgc aggccgtgcg aacgctagcc ttttggaccg tattactgtg aactactacg
     3001 gtgcgccaac accattgaac caaatggcat caatccaaat tccagaagca cgtgttttaa
     3061 tgatcacacc ttttgacaag agcattcttc aagatgttga aaaagctatt atggcaagtg
     3121 atatcggaat cagtccaacc aatgatggaa atgtcattcg cttagttatc ccgcaactga
     3181 cagaagaacg cagaaaagaa ttagctaaag atgtgaaaaa agaagcagaa aatgcaaaaa
     3241 tcgcgattcg taacatccgt cgtgatgcga tcgatgaata taaaaaacaa caaaaaaatg
     3301 gtgatattac cgaagatgat ttgcgcggat tagaaaaaga cgtacaaaca ttgacagata
     3361 acagcattaa agaagtagat aagatcgctg ctgataaaga aaaagaatta ttggaagttt
     3421 aataaaatca taaaaacaga ggggcggatc attccgct
//
LOCUS       DACDAF010000140         3442 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.148, whole genome shotgun sequence.
ACCESSION   DACDAF010000140 DACDAF010000000
VERSION     DACDAF010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.148"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(170..1249)
                     /locus_tag="IVZ69_002648"
     CDS             complement(170..1249)
                     /locus_tag="IVZ69_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006908283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP8184665.1"
                     /translation="MTQNHDNTVSRKGKHLTYSERCQIAILKKENYSNRQVADVLGCV
                     PQTINNEIKRGTVTQLNRQNQNGKVYDYYHDVYDADAGQAAYEKNRLNCGRRPLWADT
                     DAFIEWADDMMLLEKWSPDVVVGFARKHELFDPAIIPGTTTLYQWIDRGIMKTKNMDL
                     LEKLSRKPKSSRHGNRPNKRVLGKSIEERPEAVGTRKTFGHWEVDTVVGNKTKSDAVL
                     LTLVERQTRFEVILKLAGKDAESVNQAVRQLRERAGAYFGQLFKTVTSDNGSEFAGLH
                     DALQDVANIYFSHPYASWERGTSENQHKLIRRFIPKGSPIGNVSENQILRIQRWMNDY
                     PRKILGYATPHDTFVQAFRQERLTA"
     gene            complement(1405..2331)
                     /gene="cysK"
                     /locus_tag="IVZ69_002649"
     CDS             complement(1405..2331)
                     /gene="cysK"
                     /locus_tag="IVZ69_002649"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HAP8184666.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            complement(2471..3358)
                     /locus_tag="IVZ69_002650"
     CDS             complement(2471..3358)
                     /locus_tag="IVZ69_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HAP8184667.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
BASE COUNT          837 a          842 c          712 g         1051 t
ORIGIN      
        1 agccacccat ggtgacccgg ttgctcgtta ccaccaaccg tctaattttt ctaatcgagt
       61 gggcccttga caatgagctg aggcatggta gtctcccgac tggctggccc cggccagctt
      121 tccagacaca agccatgccg agggaggctc gttgtcaagg gcccacgtgt caagccgtca
      181 accgttcctg cctaaatgcc tggacgaacg tgtcatgcgg cgttgcatag cccaaaatct
      241 ttcgcgggta atcgttcatc caacgctgaa tccgcaagat ttggttttcg ctcacgttgc
      301 cgattgggct gcccttgggg atgaaacggc gaatcagctt gtgttggttt tcgctcgtcc
      361 cgcgctccca ggaagcatag gggtggctga agtagatgtt tgccacatcc tgcaaggcat
      421 cgtgcagtcc cgcgaactcc gagccgttgt ccgaggtaac cgtcttgaac agctggccga
      481 agtacgcacc agcccgttct ctcagctgtc ggaccgcttg gttgaccgat tcggcatcct
      541 tcccggccag cttcagaatg acctcgaagc gtgtctgccg ttccaccaac gtcagcagca
      601 cggcatccga cttggtcttg tttcctacga ccgtgtcgac ttcccaatgg ccgaaggttt
      661 tccgggtacc aaccgcctcc gggcgctctt caatggattt ccctagcacc cgtttattcg
      721 ggcggttgcc atgacgggac gatttcggtt tgcgggacag tttttctagc aggtccatat
      781 tcttcgtttt catgatgcca cggtcgatcc actgatagag ggtggtggtc ccagggataa
      841 tggccgggtc gaacaattcg tgttttctgg caaagcccac caccacgtcc ggggaccatt
      901 tttccaacag catcatgtcg tccgcccatt caatgaaggc gtccgtgtcg gcccataagg
      961 gccgtctgcc gcagttcaag cggttcttct cgtaggccgc ctgcccggca tcggcgtcgt
     1021 agacgtcatg ataatagtcg tagaccttcc cgttctgatt ctggcggtta agctgagtaa
     1081 cggtcccgcg tttgatttcg ttgtttatgg tctgcggcac gcagcccagg acatccgcaa
     1141 cctgacggtt ggaatagttt tcctttttca ggatggcgat ttggcaacgt tctgagtagg
     1201 ttaggtgttt tcccttgcgt gaaactgtgt tatcatggtt ttgcgtcatg tgaattcatc
     1261 cttgtctatt gagagttgtg gtaacttcaa tataacatgg aattcacgtg gcgttttttt
     1321 atttccaaat ggctaagtta attataaaat ccgccatctt taaaagtttt ttacataaac
     1381 ctatctggag aaaaaccaag tgccttatat ctcttggtaa agggctgtag ataaataacg
     1441 ttcaccattg tcgggaacca cagctaatac cttcttgcct tttcctaatt cttttgcgac
     1501 ttttagcgcg gcagcaattg cagcgccaga tgagatgcct actaaaatcc cttcttttcg
     1561 cccaacttct ctagctgttt ccatcgcttc gtctccacta atagaaagga ctttatcata
     1621 cacagaagta tccagtgttt taggaacaaa acctgtaccg attccttgga ttttgtgagg
     1681 tcccgcttct ttcccttcta aaatagcaga ttctgctggt tctaccccga ttaattcgat
     1741 tttcggatac acacgtttta attctcggcc agcgccagtg atcgttcctc ctgtaccgat
     1801 acctgcaaca aacgcgtcca agccatttac tccaaatgct tgatgtatct caggaccagt
     1861 cgtcttctca tgcacaagag gatttgcttc attttcaaat tgtaatggta aaaagtagcc
     1921 gttttctttt gccaaacgtt ctgcttctct gattgatcca gaaataccat ccgcaccagg
     1981 agtcaaaatc aactctgcgc cgtacccttt catcaataaa cgtctttcga tactcatcgt
     2041 ctcaggcatc acgatgatta ctttatatcc ttttgcaact cctaccatcg acaatccgat
     2101 tcctgtattt ccagaagtag gttcaatgat agtatcacct ggtttcagta gaccatcgtg
     2161 ttctgctttt tctatcatac ttaaagcaat acgatctttt acacttcctc ctggattaaa
     2221 aaactcaagc tttacaaaaa catctgctga atcttctggt acgattttat ttaatttgac
     2281 gattggcgtt ttgccaatca attcggtgac tgagttatag atagctgtca tcttcaattc
     2341 ctccttgtct ttgctcttct tacttatcat aatacaatct gttcatttat ggcgagtgat
     2401 tcgtctttga ctagcaaaaa aaagacaaag atataccata tatggtaatt tctttgcctt
     2461 tttatctaaa tcaaacgttt agttcttgac caactaataa agaataactg gacatagaca
     2521 tgccattttt cgccattaga tcatcaacag acatgccaaa tttttgtgca atatcccata
     2581 gcgtatcacc tgacacgact gtatatgtct gaccattatt tgtatttaca tctgttgttg
     2641 aagatgatga cgttgaagtc gtcgtagtag tcgttgttgt tgtacttgtg gttgttgtag
     2701 ccgaacctgt tgatggcgta tcaaaacggg ttaaattata agtattaatc aatgagttca
     2761 atttggcccc ataatttgga tcggtagcat aacgacctgt caagtacgct gttgcatcat
     2821 aaaaacttgt tgtattgctt ttccacacgc cagcataatg ataatcgccc gtggaaaaac
     2881 tggttgaacg aagaacattc gcatggtctt ggaaggattc ccaataagaa gaatattttc
     2941 ggaatggctc attcatcgtt acccattgtc cgtttacata ttctttggtt gccatataaa
     3001 cgacctgtcc gttatagctt cctttcacac cgaatagatt ataatttggc gcactagcta
     3061 atccggaagt gccatatgca ctttccaaca acgcttgagc gatcatgact gaagcataca
     3121 agtcattact tgcagcaact tctgacgcag accagccgat ttgatcgata aacgcttgag
     3181 gatcagcgac tgtttgagat ccttgttcat ctgcatgaac atgttgcggt accgctgtaa
     3241 ccatcatcgg cccaactaaa agactcgttc caattaaagg agcaatcgct tttttattga
     3301 tcaccatttt tcttttaggt ctatggtgcc gggcactgcg ggtcttcagc tcttgcattc
     3361 aaattcctcc tcaaaataaa aaaacttaat aaaaagttct cttcttaaaa caaacttaat
     3421 taattaaatt atacttttaa tt
//
LOCUS       DACDAF010000141         3388 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.149, whole genome shotgun sequence.
ACCESSION   DACDAF010000141 DACDAF010000000
VERSION     DACDAF010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.149"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..2232)
                     /locus_tag="IVZ69_002651"
     CDS             complement(<1..2232)
                     /locus_tag="IVZ69_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184668.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="IVZ69_002652"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="IVZ69_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          938 a          754 c          543 g         1153 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt ccagaaaa
//
LOCUS       DACDAF010000142         3350 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.150, whole genome shotgun sequence.
ACCESSION   DACDAF010000142 DACDAF010000000
VERSION     DACDAF010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.150"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            70..1128
                     /locus_tag="IVZ69_002653"
     CDS             70..1128
                     /locus_tag="IVZ69_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HAP8184669.1"
                     /translation="MVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPGLLARQGF
                     IEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQIFYITLSS
                     SRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFSFGTNYAK
                     DFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIWKAALKVI
                     RPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLVSSGIIAF
                     ICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFNKRDVISI
                     VFWYYLGSISYLYLKKEN"
     gene            1130..2200
                     /locus_tag="IVZ69_002654"
     CDS             1130..2200
                     /locus_tag="IVZ69_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184670.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            2187..>3350
                     /locus_tag="IVZ69_002655"
     CDS             2187..>3350
                     /locus_tag="IVZ69_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HAP8184671.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAA"
BASE COUNT         1120 a          414 c          539 g         1277 t
ORIGIN      
        1 ttgctgatta ctttgatagt aatttttcct gcagactttt cacaaagtga agaggaaaaa
       61 aagaaaaaaa tggtgtattt taataatgtt ttcattatca taattttttt agctgcgcta
      121 atatctatct atcaatttat ttttttgatt tcttatcatg tcccaacagg aacgccagga
      181 ttacttgcaa gacaaggttt tattgaacat cggttatttg gtgtctatac aagtccaaat
      241 gttggagcta tgtttggata tacttctatt attttaagtt taattagtgt attaatttca
      301 aaaataacaa aaacgattcg tgttttttat atgatgaatt ttatcgtaca aatattttat
      361 attacacttt cttcgtctag aggtgcccag gtagtaattt gttctttttt agtattattt
      421 cttttgttgt ttgccaattc aaaatttaga aagagcatta gagaagtact acctgtaaaa
      481 atcaaatgga tggtaagcat attattagtt ctattggtat atttttcttt tggtactaat
      541 tatgctaagg attttttagc aacaattcct gtatcgattg atagaaaagt agaagttata
      601 gagtcaaatg aatcagataa aactccactt ccagaaaaag aagtaatatt acagcattct
      661 agtgataact ccgaaatttc agctggtcgt tttacgattt ggaaagctgc gcttaaagtt
      721 ataagaccaa ctttgttatt tggttatgga gagaccgatt tctatgggaa tagcgatgca
      781 aaatttttga aaaaagtaga tcttgatact acagatgtga atgaactaaa aagagcacat
      841 ggaaacatgc ataatggatt tcttcaagta cttgtatcaa gtggtataat tgcttttata
      901 tgtatctatg ctttctatgt gttaaatatc tttagtttac tcaaaacatt ttttagaagt
      961 aaagtgaatt atgcgtttct tggtattgtt ttaattttta tactatctat ttttatagat
     1021 gaaatggtgg aggctcatgt acttttcaat aagcgcgatg tcatttcaat tgttttctgg
     1081 tattatttgg gaagcatttc ttacttgtat ttaaaaaagg agaattaata tgaagacagc
     1141 tttcattgct tggactcctt tacatttgat taatatatta aatgtttatc aaaattttta
     1201 ccgagaatca aaaggagatt tatttattta ttctgaattt gaaaacgcta gaagatatag
     1261 tgagcgtata aaagaattag ggctatttaa tgatgttgtt tttgtgaatc accggaaaat
     1321 cggttcttcc tttaaacgta aaattaactt gttaactaac cataatcaat ttttctcgga
     1381 tgatttatcc gtttatgatg aaatttttat acagggggaa aattatttca caaaaatact
     1441 tttctccaat gtttacaaaa aaaatccaga tgtaaaacta aattatatag aagatggttt
     1501 gggtacttat ttgaagaaga gtatattttc aacaagtaaa aacgttcaaa gagtttttaa
     1561 aatattaaat aaaaatagca tcttcaaaaa aaaaattgac gattattttg tctattgtcc
     1621 ggaattgtta ctttatgatg taaaaaatat aaaaaaaatt cccaaaatag atgaaaacag
     1681 taaattgatg aaaaacatac aatcaatctt tgggatagaa gaagtttttg tcggagataa
     1741 atgtatcttt tttgatcaac ctttattatc tgatggttat ggcatagatg aaacagatat
     1801 tttcgctaaa gtaaatagta tattttctgg aaaaaaagaa actttaatta agcttcatcc
     1861 tagagcaagg acaaatcgtt atggtgaaaa aaacatattg aattccagtt taccgtttga
     1921 agtcttgcta cttgaaaatg acttctcttc aacacttttg attagtccta tatctacaat
     1981 ttctttttca ccatctatga tgtttgaaaa gacgatcaac tctattatgt tggctaaatt
     2041 aattttaaat gaatatacag cattatctga agataaaaaa gaaacattga caaatattgt
     2101 tcttttctgt gaacattata accgtctatc agaagaaaaa attttactcc cagaaaactg
     2161 ggcagaatta agaaagttgg tagagtatgg gattatttaa cacactttcc aagtcaaaat
     2221 tagttaagtc cagtttctgg tatactatag ggaatttttt tattaaggga atttcattca
     2281 taactattcc tatttttgta aatattacta ctcaagcaga atatggtttg attaataatt
     2341 tcacttcatt tgtatcaatt ttttcgattc ttgttgggct aagcctaaat tcggcaatta
     2401 ataatgcaag ttttgactat aaagatgaca taaatgaatt tatgtcatcg gtactttctc
     2461 tagctacact ttcgttaatt gtgttcttat taatagggaa catatatttt ttgttttcaa
     2521 atgctttttt tgatatgaac caacttgtat ttaatttgat gttattacaa agttttgcta
     2581 gttttgtaat tagttatatc cagtcttatt ttacgattaa ctttaaccat tttaaatatt
     2641 tgattttatc ttttatatct acttttttga atattgcaat ctctgtagct ttgatgcaga
     2701 cattatattt tgatgataaa tatgttggca gagtagtcgg cggaacactg tcatttgtgt
     2761 tgataggttt agtaatttat ttaagaataa tgataaaggg tgctcatttt tttgataaaa
     2821 aacagtggag atacgcttta aaaatctctt tgccgctaat cccacattcc ttagcaaata
     2881 tagttttagc acaattcgat agaattatga ttaattctta tttaggtcct gctgcggggg
     2941 gaatatattc ctacattagt aacataggta ttattctaag cgtaatatgg atgtctacta
     3001 ataacgcctg ggttccatgg ttctatggtg agatgagtaa aaataatgaa aaaaaagtga
     3061 agaaagttag taactattat ttagtagtct ttactttgat tacgatgatt gtaatggtag
     3121 tttcgattga tttagcaaaa tttatggctc cgaaagacta ttattctggg ttatctttag
     3181 tggttccgat aaccttaggc tatttctttc agtttttata tagtttacca gttaatgctg
     3241 aattttatga gaaaaaaaca tcgtttattg cgattggtac agtagcaagt gctatagtta
     3301 atatactatt aaacatgatt ttcataccta ggttaggaat aattgctgct
//
LOCUS       DACDAF010000143         3337 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.151, whole genome shotgun sequence.
ACCESSION   DACDAF010000143 DACDAF010000000
VERSION     DACDAF010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.151"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..489
                     /locus_tag="IVZ69_002656"
     CDS             <1..489
                     /locus_tag="IVZ69_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184672.1"
                     /translation="SEITGKANNYTDGKVSEINSQLTASINEVDTTAKDAQTKANANA
                     TAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALNGKSSGGNDS
                     TILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGSDYTFAITY
                     TI"
     gene            652..1098
                     /locus_tag="IVZ69_002657"
     CDS             652..1098
                     /locus_tag="IVZ69_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184673.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            1100..1237
                     /locus_tag="IVZ69_002658"
     CDS             1100..1237
                     /locus_tag="IVZ69_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HAP8184674.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            1275..1568
                     /locus_tag="IVZ69_002659"
     CDS             1275..1568
                     /locus_tag="IVZ69_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184675.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKTLFRERRK"
     gene            1565..1789
                     /locus_tag="IVZ69_002660"
     CDS             1565..1789
                     /locus_tag="IVZ69_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HAP8184676.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            1786..2811
                     /locus_tag="IVZ69_002661"
     CDS             1786..2811
                     /locus_tag="IVZ69_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HAP8184677.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            3001..3074
                     /locus_tag="IVZ69_002662"
     tRNA            3001..3074
                     /locus_tag="IVZ69_002662"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3035..3037,aa:Ile,seq:cat)
BASE COUNT         1151 a          556 c          686 g          944 t
ORIGIN      
        1 tctgaaatta ctggtaaagc aaacaattat accgatggga aagtatcgga gattaattcg
       61 cagttgactg cttcaattaa tgaagtagac accacagcta aggatgctca aacaaaagcg
      121 aatgctaatg cgactgctat agatgaatta gacaataaga tcgatgaacg cattaatgat
      181 acagctacta ccacattaac agttacaaac gggaataccg gatcagcaaa gctttatcgt
      241 gaaggaaaaa cagtttctat atattttgtg gctttaaacg gaaaaagcag tggtggaaat
      301 gattcaacga tactaacaat tccagaaggc tatcggccac caattagttt tgagcaactg
      361 gttggctcga tagaccgttc tactttgaac agtgctcagt tatctattgg tgcagatgga
      421 gccattaaat ggcgaagaaa ctcaagttat ggatcggatt atacctttgc aattacttac
      481 acgatttaga aaagcgtgaa tcgatatgaa ggcagcatat agaccaattg aaccttacgg
      541 attcgagcaa atcattgtga atgatgaaga acatttaccg gaagaatgca cagaagtcga
      601 accaccgatt ccaaattgga aaccgaaatt caattactgg gagggaaata aatgaaaaac
      661 atttggaaat atggacgtac tggcggagag tacgcaggaa aagtattgga cgacatgctt
      721 gtatccgttc cttacacaga tcagccaccg cttgaaggaa ttcgtgctga tggcgaaccg
      781 ttaacaatcg ctgatcaaat gtttgatcct aaattgaatc aatggattat tttagcgaac
      841 gcactagatc acaacgattt aaacaatctc aaagcaatgt atgagtcgtt agaaaatgag
      901 aacggcgatt taaaacagat caatgccaaa ctcatgctaa gcgatgtagc aattaaacag
      961 gaaaatactg cattgaaaga aaaagcggat agtttagcac aaatcaattc aaaaatgatg
     1021 cttgcttcgt tacaaaatag caaagacatt tcagaaatta aagagcaact aaatccagct
     1081 tcaaagggag gtgagtagta tgtttagttt tagcgatgtg aaaatgatgt atgattgggg
     1141 ctgtttcact aacgaacaag taatggtttt cgttccgttg tgcattactg aagaaaaagc
     1201 agataaaatc attagcaaag aagagagcgc atcttaattg atgtgctttt tattttgatt
     1261 caaggagttg tcacatgatt aatttagggg aatggggagc gatagcagga tcaataaccg
     1321 ctatcgtttc tttgatttta ttagtaataa aaccaattac tgcatctttc tcgaagatta
     1381 ctgagactct ttcaaaagta agtcacaatt tagatttgct gactaaagat ttagaatcga
     1441 gcaaatcaga tcgattgatg attcatgaag aactaaagaa acacgatgaa agattagata
     1501 cacatgcaga aaaattggta gaacacacgc aacaaattaa aactttattt agggagagaa
     1561 gaaaatgaat aataaaacgt tcgaagtact aaaatggttc gcactggtaa ttattcccgc
     1621 actagctact ttcgtggggt tagttggtaa agcgctcaat tggcagtaca cagatatctg
     1681 tgttgtcatc attactggtt ttggcgcgtt tttagggagt gtgttgggtg tatcaaatcg
     1741 aacctacaaa atgttctcgg ctgaaagcga agaaggagga aacaaatgaa aaagaaaatt
     1801 actattactg cgatgagcct gttaacggct ctttttttat tacccattaa tacgtttgct
     1861 tatactatta atgacgagta taatttagcg ccgaatcaag gagactccag attagcaatt
     1921 cctaacaaaa ttattttgca cgaaactgga atagatgcac cagcaagaaa cgtagccgcc
     1981 aacatgaaaa ataattataa cggaagcaat tcttatacta cagatgttat tggtgacggt
     2041 gggattgttt accgtgtggg tgagcaagga tatgtttcgt ggggagctgg taacgctaat
     2101 ccttatgcgc ctgtacagat tgaattacag cgcacatatg ataaagcatt gtttgaaaaa
     2161 aactatcgag cttatattga atatacaaga gatagtgcaa aaaaatatgg aattccattg
     2221 actcttgatc aaggaacttc tttatttaca aaaggaatca tttctcattt gtgggtgaca
     2281 aattatgttt gggggaacca cacagatcca tatggttact tatcgcaaat gggagttagc
     2341 aaagaaaagc ttgcttatga tttagctcat ggatttaccg atgaaaatcc aacaacttct
     2401 gaaaacaagc ctgtcattga tccaacacga gctggtgcag ctaatcctac gctgacagat
     2461 ggaacaaatc acgcccacat tgatcagttt ggggaaatcg aaaacgcaaa cttgcatgtg
     2521 gctggatggc acattgctaa ctataaatac gagtatattt tcattatgga ctacaatact
     2581 gggaaagaat tagctcgagt aagagctgat ggaatttata gaccagatgt aaaccaagct
     2641 tataatactt ctggaaatgt tggttatcat gtatctttca atatgcgtaa ttttcctagt
     2701 aagaaagtct atgtaatgat gcgggcaacg aatgatccag agggaaacac taaaggcggt
     2761 gcgcaagatt tccatgacaa acgttggtat ttaaatattc ctaaacgata aaaatagctc
     2821 ctcgttgagg agcagtacat aactatattg acaactataa aaattattcg ataaaatagt
     2881 gatgttatcg catatcttca ctatcaccca taaatagtca cactccaagc tatgcgataa
     2941 caggtttgtt gccacacatt ctactggttg attgtttatg gctttatgtg gcaacaacca
     3001 gtacccttag ctcagttggt cagagcagac ggctcataac cgtccggtcg taggttcgag
     3061 tcctacaggg tacattaacg tagccatttg aatcgttctg tgttagaatt tttttgaaga
     3121 gtattataca agctaaagct tttcttcatt gccactcaaa tgagtggctt ttttatgtat
     3181 ccttttatgg attaatgaaa ggatgtttca catagttata cttctgtata tttgaaaagt
     3241 tttactttga tttttaaata gaaagacatt tgggttaaat tgtgagataa taataaagaa
     3301 gagtttaaag cgcaccccaa accacttccc cataagt
//
LOCUS       DACDAF010000144         3323 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.152, whole genome shotgun sequence.
ACCESSION   DACDAF010000144 DACDAF010000000
VERSION     DACDAF010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3323)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3323)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3323
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.152"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(88..1035)
                     /locus_tag="IVZ69_002663"
     CDS             complement(88..1035)
                     /locus_tag="IVZ69_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HAP8184678.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
     gene            complement(1040..1792)
                     /locus_tag="IVZ69_002664"
     CDS             complement(1040..1792)
                     /locus_tag="IVZ69_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HAP8184679.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            complement(1793..2701)
                     /locus_tag="IVZ69_002665"
     CDS             complement(1793..2701)
                     /locus_tag="IVZ69_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HAP8184680.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            complement(2701..>3323)
                     /locus_tag="IVZ69_002666"
     CDS             complement(2701..>3323)
                     /locus_tag="IVZ69_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HAP8184681.1"
                     /translation="LKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNFFVS
                     NKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETGIVG
                     TLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHDNNY
                     SHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
BASE COUNT         1090 a          621 c          410 g         1202 t
ORIGIN      
        1 ttctatccca gatttgattt tacaaaactc atcagtcctt attgacaaag agcctgaatt
       61 taccctctaa tcttatctta gtatgtttta attgatttca gttttcaaat aattagtcat
      121 tccacttaaa ataccatatt tcggttgata gccaattgac tggatcttag taatatctgc
      181 tagagagtca tggatatcac ccgaacgctc ttctttgtat tcaagtgtca attctacacc
      241 gagaatttca ttgattgcat gaatcaattc caaaagtgtg gttgctttac ccgttccaac
      301 attgaattgt ttccccagtg cagcttcctc attcgcaact aaaagtaatg cttggattac
      361 atcatctata taaacaaagt ctctagactg gcttccatca ccaaataatg taaatgaagt
      421 tgcttctcct acgatttgtt tcttatagcg atctacgaga atagaaatca caccactgta
      481 tggagaattc ggattttgat ttggaccata gacattgaaa aaacgaactg cgctaccggg
      541 tacatcatat aaatgacaat aatctagcac atattgttct gcagcgaatt tatcaaccgc
      601 ataaggcgtc aatgggcgaa tcacggactc ttcttttttt ggtaaagtcg gttcatcccc
      661 ataaacagcc gctgaagaac taaacacgat ccgttttaaa tcaggttgat acttgcggat
      721 caattctaaa atcattaata cactttcaaa attcacacga tgtgtttcta ctggtcgggc
      781 aactgaatct gccacactag caactgctgc taaatgaaag atataatcaa atttattagc
      841 tttcatgatc tcttccatca aggatttctc agcgacatct ccctcaataa aagtgatatt
      901 tttcgtcata tcaagatttt ctacttttcc cattgataag tcatcgacga cgattaccac
      961 atgttcttct cctaaatgat tggctaaggt agaaccaatg aagccagccc caccggtgat
     1021 aagataacag ctcatccttt tacctccgat ataaataatt atagatatct tgaagctccg
     1081 aagaatcttc taaaaattta ggaaacaaaa attctaacca tttaaaatct tcttcactat
     1141 caatatctaa aattagataa tctctcattt ttattatccc acattgccca tcaaaaatat
     1201 aattactttt ttttagaaat tcaggtttaa aagaatacat tgaggcattc atttcaaaaa
     1261 cttcaggtgt ctgttgccta gatgtgtatc ttgatttatt aactatagta acttcatttt
     1321 caattctttt taccatatta aaatagggat tacgtcttgc agaaacaact gaaaagtaga
     1381 cgtctttatc taaatttttt agatgttcat ctattaattc ttcaagatta gaaacttcac
     1441 gtaaaggtga agtcaaatct aaatctataa ttaaatcaaa tatattatct tctctttcta
     1501 gttgtaagaa tgaatcacgt atcacttcaa ttttccctac agtatctgta gctaattcag
     1561 gtttacgttc tacaattttc acagacggat ttaacttagt cgtcaattct actaactcat
     1621 tactgtccgt attcaaacaa gtcgtgcaat tatgttcagg atgtttttgt tgatagatat
     1681 ctatcattgc taaagcgaaa tggactaggg gctttcctgc caaatatttc aaatttttat
     1741 ttttaaaccc cttagaccca gctctaccac aaatagtaaa taaaatttcc atttatttct
     1801 cctcagctat tttcaatact tcgtttgcat gatataaatc attccagttt tctttgcctg
     1861 ttactacgtt ttcaaagaaa tatttcaact ccttctcata catatcatta gcagattcag
     1921 gcatttcttt aacaatgttt tcttcaaaac ttattttatt atttaataag tcaacattga
     1981 tacattcatc taaagtaaac aattgaaatt ttcttgtagg aactcttcca aaataatcta
     2041 aatgaatttc tataatttta tcatcgtatc tcaatatata tgttgctaaa tcattactgt
     2101 taatttcaag attcgaatat ttaccaaact gtttttttac tgatttaggg aaaccaaata
     2161 ggtttataat ataatccaat tcatgtatac agtctaattc tactcctccc cccatagatt
     2221 taaaggcaga ataattattt ctataatcag taccttttct ccaatcagga agataagtag
     2281 aacaaatagc tcttacagaa tatacttttt tactttgaat actattacga acaacttcca
     2341 tgatattttt atacctcagt ggagcagcaa cataaatatt tttgtaatca taattatatt
     2401 gagtaagatc aatactctca gaaaaagcag gtttttctaa aaatatgtaa tcaacttttt
     2461 caacaattac atttagtgtt tccagatgct taaaagtcgg atttgtaata aaagctatat
     2521 cataatgtgt atccaaatcg tctctatttt gaatatacgt tatttcttca aactcttttt
     2581 ttccactgct actataagct gttatatcaa aattaataga attctttttt ccatagctta
     2641 ttagattttt tagatgtctc tttccaattg accctaaccc aaaaaaaatt actttcatca
     2701 ttaatttacc tcaatgtcgt taattaagtt aataatatac ttatcttttt caaaagtata
     2761 ttggggttcc attttctttt ccaaaagcgt gaaaaattct ttaatctcct ctaaatatgc
     2821 atcttcaata atagtatgtg aataattatt atcatgcata acctcatcgt acaattgaat
     2881 atctgtcata ctagaagttt cttcattcca tgaaaataga gaatccgggt taccttccca
     2941 ttctattaaa atcttttcac caattatagt taaatttctt ttagctactc ttgaaacaac
     3001 atctacactt aaagttccaa ctataccagt ttcatgctca ataataagag tgaaactgtc
     3061 cgaataatca atatcaagat tggataattt ctgggtcatt acagtaaacg atttaacttt
     3121 cccaaatgta tctataatcc aaggtaattc aatagcgaat atttctctac acccattagt
     3181 ttttttgttt gaaacaaaaa aattgcgata atcttcccaa ggatgccagt cgggtaaata
     3241 ctgtcctaca tggtattgat aagaaatttt tttattatgc gtcactttag acttaatata
     3301 ttgaatttct tttctcttca aaa
//
LOCUS       DACDAF010000145         3309 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.153, whole genome shotgun sequence.
ACCESSION   DACDAF010000145 DACDAF010000000
VERSION     DACDAF010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3309
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.153"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(620..2233)
                     /locus_tag="IVZ69_002667"
     CDS             complement(620..2233)
                     /locus_tag="IVZ69_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HAP8184682.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2374..3282)
                     /locus_tag="IVZ69_002668"
     CDS             complement(2374..3282)
                     /locus_tag="IVZ69_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184683.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
BASE COUNT         1064 a          566 c          584 g         1095 t
ORIGIN      
        1 gtattacaat ttgagtgtaa cataaatggc ttttttattt gtctcgctta attatacaaa
       61 cggcgttgtt aaataaatag gaacaaaaaa attaaattat ttaatacaca cattagggat
      121 cattcattga aggattagaa gacaacgagg atggcgaaaa atatgattac aatagaaaag
      181 tcgttctaaa ccaatcagtt cctagtatca cacaacgcaa gccagtcgat ttggtgagat
      241 tagaggagtg aaagcaaact ttattatata agaaaaaata ttcgaaaggg atgctagttt
      301 aggtactagt gctgatagat taatatgatg cctcgtaata ttaggcgtag ttactctaga
      361 gacatcacta tggactatga tttgtctcag agtcacaaca tgttttttta tgaaaagaaa
      421 cagctaaaat aattaaattg cgcaatgttt aaactttctt aaactataac ctaataaatg
      481 tgaagaaata atgcacaatt tcttcacatt tatcttctat tctatataca taccaaccaa
      541 caaccctata tactttttca tttttactcc tcaagtaaaa ataactccta gaccgcggct
      601 acccaccgcg gtcgtttttt tattcttcaa tcaaaatcgc tttgataccc aaacctgcca
      661 agattcgggc agaagtataa gtattcaatc ctcttctgaa agtaatgtaa acttttttat
      721 cttttgggat ttcattgatt cgatctcgta actcattcat tggaatattt tttgttgccg
      781 agatactgcc agaaggtgct ttattaggtt cacgtatatc taaaaagaac gcttctttca
      841 aatcgttttc gggtatatca cttgctttga tcgtttctac gatattcgtc atttgattga
      901 ttgcgacata accagctata ttcaacgggt cacgggtagt agaatacggt ggagagtaag
      961 gcaactccaa atcaggcaaa tcaaagactg tcaagtttcc ggtgattgct acagaaagtt
     1021 ctcccatccg tttatcgaca cctttttctc caaatgcttg tccacctaaa atacgaccgc
     1081 tatctgcatc aaaaatcagc tttagattta atcttgtagc ttctggatag aaataggcat
     1141 ggtcaaaggg agtgataaaa acagttttat aatttgttat gcctgatgct tttaattcat
     1201 gttctgtcat tcccgcataa cttgctgtat gatcaaagat ttttgcgaca cctgcaccaa
     1261 tatatccgcg atagcgcata ggcgtaccat ttaaaatatc tgccagcata tgtccttgac
     1321 gattggccgc actggaaagc atactttgga tcggctgacc agtcactaca ctagtcgttt
     1381 cgataatatc gccaatcgca tagatgtccg gcagattggt ttgtaactgg tcatcaacaa
     1441 tgatctgacc tgtatctgat aattgtatgc cggttgcttt caccacttca ttcttcggag
     1501 aaacaccaac agcaaaaatt agcatatcag cagaaaggac ggagccatct gataatacta
     1561 tttctcgacc tttatcacgg atctcagtaa ctcttgtttc taaatgaacg gctaatcctt
     1621 ctttcagcaa tttgtcataa actaaattag caatttctgg atcataaggg aaagcgactt
     1681 gtggcaattg atcgattaaa gtcacgtcta agccgcgatg cttgaaattc tcagctaatt
     1741 ccagacccat aacacctgca ccaagaatga cgacatgttg tggatttttt tcttcaagga
     1801 acgatttgat tcgatccgca tccgtcacac tacggaggac aaagccgttt tctgcttcaa
     1861 aaactccggg aatatccgga taatctggtc tagcaccaga agagatgatc aacttatcgt
     1921 aatctgtttt tatttcttca tttgtggata ggtctttaac tgttaatcgc ttagtagaag
     1981 gatcgattgc tgttacttcg tgtttagtaa agacatcgat gttgtttttt gttttcaata
     2041 tttctggtgt acgttcgatc agcgagtcac ggtcagtgat cacacctcct aaataataag
     2101 gcaaagcaca acttgcataa gaaatatttt ctccgcgttc atagataatg atttcgtgcg
     2161 cttcattcaa tcgacggaaa cgagtggcaa atgaaggacc gccagctaca ccgccaatga
     2221 caacaacttt cataaaaaca tctccttttc tacgttgatc gtactatgtt atggtaaaaa
     2281 acagcaaata attgtgccgg aaaattattg tttattttga atagacagaa aatatagaga
     2341 aataatttgt ggataaaacc taaaaatttt tttctatttt aaggatagat aatactttga
     2401 aggggataac cctgtatatt ttttaaaagc tgaagaaaaa tgatggatcg aatgaaatcc
     2461 taatatatct gcaatttctg tataggttaa ttcattttct agcacgagac gttttgcttt
     2521 ttccattttt agttctttaa aatagctaat aacacttttt ccattcactt ttctaaaatg
     2581 tttttttaag ctggctggac tgataaaaaa aatttgggct aattgttcaa gcaaaaaatt
     2641 ttctgaaaga tgttcttcta aatatcgtat gattggatca actaattcat ctgaataaag
     2701 aatatgcttt tttttaggaa tgactttctc atttgaaggt attgtcaata aagcaagttc
     2761 ctgttgataa tgccttggta aggaagacaa ttgaattttt tgcagacaat aagtaactaa
     2821 taaggaaagc aaatgaatgc tcatctgttg gcatagtatg aaaaaagaat tgatttcctg
     2881 atcataggaa atagctggct tactatgttt tagataatca attttgaact gttcattttt
     2941 cagaaaagta atgatagatg ttatttcttg atctatagaa aaagattgtc ccgtaatatg
     3001 tgctaataat tgctcatcaa aataaaactg gataatgata aaagtttgtg tttccttttg
     3061 agtagaaaag atttggactt cttgctgttt atcaatgaat aaaagggaag gattatctag
     3121 ttctatagat ttatgtgcaa attcagcata taaattagcg ctttcattta ttagtagtcg
     3181 aaaataggga gcagcagata aatgaagatg ggtatctatg gaataggtta gtgttttttt
     3241 gacaagattg gaggattggt tgtttgttaa caaaagaacc actttccttt ctctttttat
     3301 ataaaaagc
//
LOCUS       DACDAF010000146         3232 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.155, whole genome shotgun sequence.
ACCESSION   DACDAF010000146 DACDAF010000000
VERSION     DACDAF010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.155"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(449..1063)
                     /locus_tag="IVZ69_002669"
     CDS             complement(449..1063)
                     /locus_tag="IVZ69_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HAP8184684.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(1669..2046)
                     /locus_tag="IVZ69_002670"
     CDS             complement(1669..2046)
                     /locus_tag="IVZ69_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184685.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(2346..3227)
                     /gene="galU"
                     /locus_tag="IVZ69_002671"
     CDS             complement(2346..3227)
                     /gene="galU"
                     /locus_tag="IVZ69_002671"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HAP8184686.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
BASE COUNT          980 a          662 c          499 g         1091 t
ORIGIN      
        1 tccttcaatt tttgtgtatt ttatttctat tagaaaaagg tatcctgttg gacaattttg
       61 ttatatcagg taaacttcat tgcaataatg ataacaaatg tactataatt actttgtaaa
      121 gagttttggg gaagactctt tcatcaacgt gtattaagag acaagaaaga atccatatgg
      181 attctttctt gtctcttttt ccactacttt ttatttttct gacactacat attcttataa
      241 ctcatttctc ataactgtga aacaacttat aaaaataaca aactttaaac aaaacaagct
      301 taaaatcaaa gatgatccat cttaaaataa ctaaaacaaa aaaagtagtc gttgttaatc
      361 ctcattaata atcgttttct ttttttcaaa cgctccattt ttatgtggaa cattattttt
      421 ttaaggaact ttgtcaacat gtggataact attttccact tgtgtcctgg actagctgtt
      481 ttgctgtaaa atacaaaact tgctgcagca aaaagatcgt tgcaagagag gctgttccgc
      541 agatcgctgg atctagattt ggcaaagtca agactgcatc atgtaaattg gcgtggttgt
      601 ccaaaaccaa atcagcaaat tcaaataatc gcaaaccact gctatgttgc gatttgatac
      661 ttcgtgacaa atcaaatcca gtaacaatga ttaatggatg accattttct ttgatccact
      721 gagctagttc gatgattgcc gggtttcttc cttcattcga aagaagaaga aaaatgtctt
      781 ctgatttgac agaaagctga tcaataattg cctgtcctgc accttctagc gtttcataga
      841 cacctccggc tggattttca atcaatatac ttggtacaag atccggggtt tgatcccaaa
      901 attcaaatgc tacaccactt agtgtgcggc tagcatatat ctgcaatcta ccaccttgat
      961 taatttgttt cgcgatccaa gtgccagctt gaagcatcag cggctcttct atccttaatt
     1021 tctcttccaa ttggtgataa tagtcaaaat aacataaact catttatctc tcccgcctag
     1081 ctatacttga catgaataga aacagctgcc taatctaagg aagtacataa aaaaacagta
     1141 gttagacagt aacacatgtg gtctttgctg tttcaaacac aaaaaaggca ttgaacgaat
     1201 acgcccaata ccttgacata gcaaataaaa caacgtgcag accatggaaa atatctacat
     1261 aggggtagaa ttttcaccct agattaggta caataaatta ggtcgatgca ctgcattgac
     1321 tatggcaaaa tgatcggtca gggtgtatgt gtgtgactgg tcattccctg attcttagcg
     1381 ccaactaagg gtcagggagc ctttttttat tcagctgttt ctatctgaat ttattgtaag
     1441 taatctctta tccaagtgca agcaagaaaa tacaaaaaaa cattggtatg atttatatat
     1501 atataaataa cataaaaaaa ggaatggctt atcccgatac aacaagcatt cctttaaaaa
     1561 agattctttt atataagtga aaaaagcttt tttccaccaa ttaaataaat ctctcatctc
     1621 aatagtttat ccattatttt atcttttttt gcgtatacct actaaatatt accgtcttct
     1681 tctcgttctt ctactttgtt cgagagaatc tgtactagaa aaagtagttg tatgtctacc
     1741 ttttctgcct atccgagact ttcttttcat atatgggata taaatgatta gatacagtac
     1801 agcaaaaaat aaagcaaata cgcaagcttc ccaactacct aacgccaatt caaccatcaa
     1861 ggtagcaacc ccaacggatg ctgcatacca gataaaaatc agaaacgttt ctttttttct
     1921 gaccatgcga aacatgataa atagactaat aagcaatagt ggcaacacaa atatccaatt
     1981 gcttccttcc atcagccact tgagtatatc aagcagcgac tgtgcaacag cgactaattt
     2041 tcccatagtg aacacacacc tttttttata attaaaaaat tcgctttttt attctactat
     2101 gaatcttctg gcttggcttt catttctctt atgtaatcat tttcttttat acaacttaaa
     2161 aaaaaattaa accattagca taatattttc tgaatctatt cacgaaagtc tttttctatc
     2221 tttcgttttc cacgactcaa ctgatctaga gtcaaaaaac taaaacgaca gttgcgcaaa
     2281 tgacgcacaa gctgccgctt taataacaaa tagcctttca ttctcagcag gccacttatt
     2341 tccagttaac tttctgttct tagcttttta ctcaactgga taatatatgc acttaatgaa
     2401 gtcccaattt ccgaatgttg aagtccatat tcaatatttg tcttcatata tcctaactta
     2461 tcgcctacgt cgtatctttt tcctttaaac tctctcgcat agaccgcctc tgtctggtta
     2521 agagtctgaa gtgcatccgt tagctgtatc tcgtttcctg ctcctggttc ttgagtttct
     2581 aatatctcaa atattttagg agtcagtaga taacgtccga taatggctaa attacttggt
     2641 gcttttccca tttcaggttt ttctacaaac ccttttactc tgcaacgacc cttttcgcta
     2701 tctgttttag gatcaataat tccgtattta gatgtttcat tttctggtac acgcatgacg
     2761 gcaacagcgg aagcttgtgt ttcttcataa tccatcatca attgttgagt caatgggata
     2821 tcatctttca tcaaatcatc ccccagcatg acgacaaacg gttcatttcc tataaatgct
     2881 tttgcttgaa gcacggcatc ccccagtcct cttggatgag attgacggat gaagtgaaga
     2941 ttgacttgag tcgtttcttc aactaaagcg agtaattctg ttttttcctt ttcccgcaaa
     3001 ttgttttcca attcgatatt tgcatcaaag tgatcttcaa tgggtctttt ttcttttccc
     3061 gttacgatca agatgtcttc gattcccgaa tccaatgctt cttccacaat aaactggatc
     3121 gttggtttat ccacgattgg aagcatttct tttgccatgg cttttgttgc cggcaaaaaa
     3181 cgtgttccta gcccagcggc aggaatgact gcttttttga ccttcacttg ct
//
LOCUS       DACDAF010000147         3202 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.156, whole genome shotgun sequence.
ACCESSION   DACDAF010000147 DACDAF010000000
VERSION     DACDAF010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3202
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.156"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            825..1037
                     /locus_tag="IVZ69_002672"
     CDS             825..1037
                     /locus_tag="IVZ69_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184687.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPTELVS"
     gene            complement(1315..3114)
                     /locus_tag="IVZ69_002673"
     CDS             complement(1315..3114)
                     /locus_tag="IVZ69_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HAP8184688.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRSFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
BASE COUNT         1134 a          560 c          562 g          946 t
ORIGIN      
        1 aatattatca tcgaaacagc taacaaaatt gtcataaaaa acgagatggt tgatattaga
       61 acttgtgttt ttgtttaggt ctagagataa agagagacaa tttccaaata tatgtaatga
      121 atacaaaaag acgtttgtcg cggattaccg ttacaaacgt cttttattga ttttccgaga
      181 tctcatcagt cgccatttgg aatggttcac tccttatcta gattcgttta atgctcggac
      241 tgcttgttcg attgtaatac caaacgcaac gttattttcg ttttgtgcat caatcgccat
      301 aaaacggtta gaagttgtat caaaagctac gcggtattgc atatttgttt ttgtaaacgt
      361 cataaaattc atctcctttg taatgtaatt tagttcttga aagtttcctt taaactttcg
      421 aacttatacc aagtttagca tcgtacgttt tttgatgcaa ttaaaaagca tttatcattt
      481 tccttattta ttttttctta aatggtttag ctattttctt ttaatccgat aagtagccca
      541 atcatcaagg ttacaaatac tattgcttga atataaatca tatgctcacc tctttataaa
      601 taacttagca atataaagaa aaaaacgcac gaacaacata ggaatataaa caaacgtttt
      661 tgtcacaacg tctaagatcg tgttaaaaaa tagttatcta aaaagcagaa agatactcaa
      721 aataaaaaat aaaaaaatga ataaaaacgt tttcaaatac aaggtaattt gttattataa
      781 aataaagaaa aaacaaaata aaaataaaga aaagagggaa tgaaatggta aaagcagaag
      841 taggaagatc ttatatatgc aaaccgatcg gagtatctca tgaactaatc ggctgtattg
      901 aacgtacata tatcaacacg gctgtcgtgt atgttgaaag ttatgaccaa cgagactatc
      961 aacttatcaa tgaaagcaag tatcgcatgc tcgtaaaatt ctgtgatatt agcgcaccta
     1021 ctgaattggt ttcttaaaca gtatttttga gaattcgcaa gaactccctt ataatataaa
     1081 taaagacaga agggagcgag aagatatgcc aaaaagaaaa agttcaggga aaatgggaat
     1141 tattcttgca gtgatctctg caattcctgc tattttagct attgttcgtg cgatgaagga
     1201 atcaagagaa agttaagcac acattatgag cgtcaaacaa aaaacgcata tacctgcggt
     1261 ggcaggttat gcgttttttg ttgtataaag acttttttca ttaacgattt ttgattagcc
     1321 gactcccaaa acaaaattta gcagtttatc tgaataagtg atttcttcat ctgtttgttt
     1381 cacactttca tttagtagtc ccatctcatc ggttatgata ccatccacac cataaaacat
     1441 catgcgactc atggcatctg aatcgttgat tgtccataca tatacttctt ttccgtcttg
     1501 gtgggcagaa ttaatgaagt tacggttgat cgtactatat tccattgtca gaaaatcagc
     1561 aggcgtcaca gggggcccaa caatattgaa aggtaagatg tagcccacat aaaagtttgg
     1621 ttctgcttct tttaaatctg aaacggtttg gtacgtcaaa ctttgcaaaa tatgatggtt
     1681 ctctaagata actttgcggt atttatggac aaatcgttcg acaaggtcat ccgaatcttt
     1741 tttagaggtc ttgatctcaa taagtaattt ttggtttagc ttatgtgctt tttccaaata
     1801 agaatcaaaa gaacaaacag gggcttgcac tccgttttca gtaactgtaa gatttgtcaa
     1861 ttctttcaat gtaagatcct gtggtgttcc atttacccct gttaagtgac gaagatttgc
     1921 atcatgcatc actacgaaat gaccatcttt tgtttcctga acatccatct ctacataatc
     1981 aggatgatag tctctgcttg ttttttcaag tgcttctaaa gtattttgcg ccccattttg
     2041 ggtactcaca cctctgtgag agacagtcac tggttttgtc tgaacagctg aagtcagata
     2101 atccatattg taaagacaga cgccaatacc gaaaaaaact gcaaaaagag tcaaaccagt
     2161 gtttttcagc gcagagaaac gcaagttggg ggcttgtggg ataaaccact tagggatctc
     2221 aggcaagaag ccttcgtcat ccatgaaatc aacaatgata taaaaaatcc ctacggtaga
     2281 catcacgata ttgaataata aaatcccttg taaaagcgtc atagcaaaca cagcgctgat
     2341 caatgcatag tctgggaaaa attgttcaac catactttgt gccaaaataa caacgatata
     2401 tcctaaagaa gaaaggagta aaatcgtacc gccaatcaca ataaattggc ccgtgatggc
     2461 caaaagacgc gatttggtca atgaccagct ttcccgaatg gctgctcgaa aagaacgatc
     2521 tcgtagaatc atttccggta aagcaaaaat cagtcgaatc ccaatatagc caaggaaaat
     2581 ataaacgagt aaaaaggaac tgacgatgat ccaacgatta gcaaaaataa aatccataat
     2641 gaaagcgggg atttttattt ttgacagtag atcagaatta aaacttaatc cgctgatcgg
     2701 tagaatcaat aaaaaataag caaggaaaaa caaaaaagta atgggtctca ctttcttcag
     2761 ctgaagtatc gtcaagtgta agagttgctt caaagagatt ggttctttct ttttaataaa
     2821 aaaaacactc atcaaaagaa aagtaaattc gaaataaact aacagtaaaa tcgtcatcaa
     2881 aactacgatt aacgagagta gaaccccagg atgttgagaa aaaattgaag gaatattgtc
     2941 ataagacaaa tagtcaattg cccctcggtg taaaataaaa cgggtcgtac tgctcaataa
     3001 gggtaaacaa ataaataaaa taaagccatg catcagcaag acatcacgga aataagcttg
     3061 tgttcctttt aaaaagtccc aagcattacc taagctacgt ttcaaataat tcatcctatc
     3121 acctgctctt cacattgtag cgcaaatcta atgaaaaagg aaagggtgca gtgtgttttg
     3181 cagacccttt cccagattta ac
//
LOCUS       DACDAF010000148         3142 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.157, whole genome shotgun sequence.
ACCESSION   DACDAF010000148 DACDAF010000000
VERSION     DACDAF010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3142
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.157"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..419)
                     /locus_tag="IVZ69_002674"
     CDS             complement(<1..419)
                     /locus_tag="IVZ69_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184689.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYSINGTNADLIVDGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPS"
     gene            complement(429..1166)
                     /locus_tag="IVZ69_002675"
     CDS             complement(429..1166)
                     /locus_tag="IVZ69_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP8184690.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVAGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINHFNCTGLSKIQIYRNGLR"
     gene            complement(1217..>3142)
                     /locus_tag="IVZ69_002676"
     CDS             complement(1217..>3142)
                     /locus_tag="IVZ69_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP8184691.1"
                     /translation="TIWSALGEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQ
                     ELNGKIAELKDSLAPIGNTIIDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAA
                     FTLLMPIIVGFMALGGPTTLIIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLG
                     GTWESIKEGASSVWDGVKETWSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQ
                     ETWQAFVDWVSNIWNGVKEVWSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAG
                     QLLGAAWQAVWTPISDFLKNTWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAI
                     STTASNIWNSISATASSIWNSIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISST
                     ASNIWNSVTSSISNAINAAKSAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISS
                     KVNDGKNAISSGWSNLTGIVSDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFD
                     NLNISIPHIPLPEFIMEGSFNPLKGQIPHLRVKWHAKGGIFTKPTLLGGMNGVGEAGP
                     EAVLPLKRSVLQEIGDRILSSTSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQ
                     IIDSITKIQNDNASAWR"
BASE COUNT          945 a          669 c          493 g         1035 t
ORIGIN      
        1 gaagggatag ctggtttcgc taaaactttt gcgttttgcc atgcctgagt agcagtgatc
       61 ttttctgttc cgctgtcata tttattcaac accgattttc ttatatcatt gaaaataggt
      121 tcagctttta cttctatcgt attgcctatt acagaagttt ttgcataata aatccgtaga
      181 cgctgttttg ctcgattttc atctacataa cactgaataa tacgtccgtc tacaatcaaa
      241 tctgcattag ttccgtttat tgaataagta ccctgaaata tctcggctcc gtttagttta
      301 ttgctaacag tagctgttaa ccagtctgac aaagcgccta aaccttgcgt atcatataaa
      361 tgttcagcta aattattcgc gtcattttta tcgtaaatag ttattaaatt atcgatcatc
      421 tatttcacct accttaaccc gttacgataa atttgtattt tgctcaaacc agtgcaatta
      481 aaatgattga tatccacttg caatgtcgga tattgcatgg tcttcatttt gttggaccga
      541 tctaaaatat ctccgtccga ttgctcttcg tagcaaagca tcaaatcact atcaatgact
      601 acatcagttc ctgctactaa gccttcgaaa ctaaacacat aatcatttaa gatgaactgg
      661 catgaagtag ctgaaggagt gatgataatc tttggaaaac tttcttctaa actattattc
      721 agcaagttaa atgactgtgg tttatctacg gttataggta catcttcttg aactcttgcg
      781 aatggtttcg cagtaatatt tacatcgaac tctccccatt caacaatatc gttttctgca
      841 tccccaatat cgatagtctg gataacgtaa tagacgttgg gatcgtcaga gaattctaat
      901 ttctttgcat agtttaacca atgacgcatg atataaaacg attgcttgaa cgcttgatgg
      961 tcttccacat cctctaaata gttatagtgc aatgtaaacg acatatcttc aaacgagtaa
     1021 tcttgtacta agccacctaa cctacctaaa acagaagttt caactctctg tctttttgga
     1081 gaaggtatgg ttggtctttc agctaaagcc aatttatgca aataatcagg aaatccatcg
     1141 attatagaat gtatacaatc agtcattttt tcacatcctt tttaatacta aaaaaacagg
     1201 agaaatactc tcctgtttaa cgccatgccg aagcattatc attttgaatt tttgtaatgc
     1261 tatcaatgat ttgttgagtt gtttgcttca tagtaacctc atctgcgtta ccatcaattg
     1321 tgaaattgaa ttcgtagtta ttcacaggtt gaatcgtttg tgccctagat gaaactgatg
     1381 tgctactcaa gatacgatca ccaatttctt gcagcacaga tcttttcaaa ggtaaaactg
     1441 cttcaggtcc tgcttcaccg acaccgttca ttccacctag taaagttggt ttagtaaaga
     1501 tacctccttt agcatgccat tttacacgca aatgggggat ttgacctttt agcgggttaa
     1561 agctgccttc catgataaat tccggtaacg gaatatgtgg tatagaaata ttcaaattat
     1621 caaaaatgcc actgattttg tctctaatcc aatcaattgg agcgctaaca gtctttttga
     1681 tgccttccca tatgttagca attgtacttt taacattatt gaatatgtcg gaaacaatac
     1741 ctgttagatt ggaccaaccg cttgaaattg cattttttcc atcgtttact ttagagctaa
     1801 tagtgcttgt aattccattc caaagattca aagcagtatt tttgataccg ttccaaattc
     1861 cgctaatcca cgaagatata ctattccaaa cactttgaat ggcactttta gctgcgttta
     1921 tagcattgct tatactacta gtcacactat tccagatatt tgatgctgta gagctgattg
     1981 aattccaaat tccacctaac caactagata cagttgacca aatattttga attactgtag
     2041 cagctgcttg taccaagcta gtgattgtat tcttgatact gttccaaata ctagaagctg
     2101 ttgcactaat tgaattccaa atatttgaag ccgtagtact aatagctgtc catataccat
     2161 tccaccatgc cactactgga tcaaatatag tatggaatgt agttacaatt ccattccaag
     2221 cgatgcttac ccattgtgtc atagtatccc aagtgttttt aaggaaatca gaaataggtg
     2281 tccaaacagc ttgccaagct gcgcctaata actgtccagc tacatcaaaa atacccacga
     2341 taatattaat accggcttga atcaatgacg ttattaaggt ccatggtatt tgaacaattc
     2401 ctacaatgtc tgcccaaata atcgaccata cttctttgac tccgttccaa atatttgaaa
     2461 cccaatcaac gaatgcttgc caagtctctt ggactccttg ccagatgttg gaagctcctt
     2521 caactaatcc gctccatagc tctccaaacc aatcagaaac tccttgccaa atatcttgaa
     2581 cccaatctac aaatccagac caggtttctt taactccatc ccaaactgat gaggcacctt
     2641 cttttatact ttcccaagta ccacccaacc aatcagtgaa tttactccat attcccttaa
     2701 accagtcagt aattgcgccc cagtttttta taattgctat aactccagca ataacagtaa
     2761 taactgctcc tattattaat gtagtaggac cacctagagc catgaagcca actattattg
     2821 gcattaataa agtaaatgca gcagtcaatc cgccaatcgc tacggcataa tcctgtactg
     2881 gttgtggaag attattaaac gcatcagcca tctttcctag aaaatcaatt actggttcga
     2941 gtgcatctat gattgtgttg cctataggag ctaatgaatc ctttaattca gctatttttc
     3001 cgtttaattc ttgtaacgga gtagtagaat cttcattcat tttttgtgca gatccactaa
     3061 catcatcaaa tgtatggtta acatcagtca aagattggac aactttcatc gcattatctt
     3121 cgccaagtgc agaccaaatt gt
//
LOCUS       DACDAF010000149         3139 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.158, whole genome shotgun sequence.
ACCESSION   DACDAF010000149 DACDAF010000000
VERSION     DACDAF010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3139)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3139)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3139
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.158"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            17..280
                     /locus_tag="IVZ69_002677"
     CDS             17..280
                     /locus_tag="IVZ69_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HAP8184692.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            274..624
                     /locus_tag="IVZ69_002678"
     CDS             274..624
                     /locus_tag="IVZ69_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HAP8184693.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(648..1262)
                     /locus_tag="IVZ69_002679"
     CDS             complement(648..1262)
                     /locus_tag="IVZ69_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8184694.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRL
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            1576..1998
                     /locus_tag="IVZ69_002680"
     CDS             1576..1998
                     /locus_tag="IVZ69_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184695.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            2008..2211
                     /locus_tag="IVZ69_002681"
     CDS             2008..2211
                     /locus_tag="IVZ69_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184696.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            2422..3006
                     /locus_tag="IVZ69_002682"
     CDS             2422..3006
                     /locus_tag="IVZ69_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8184697.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT         1086 a          465 c          575 g         1013 t
ORIGIN      
        1 gaaagaggtg tctactatgg aaatgttacc tataaaaaaa tggggaaata gtaatggcct
       61 tagattgcca aagtatatta tggaatatct tggaattcat acagaagaca aagtgaagat
      121 aatacaagaa gaagtaaacg gtcagaagcg gctaattatc gaagcggcta atatagaaaa
      181 tgaattaaca attgaacagt tatttgaaaa ttacactgat gaaagaaatc atgtgacgat
      241 tcaaaattta ggtgaagcag taggtaatga aaaatggtga gaaaacctag acaaggcgat
      301 attctattat tgaatacagc acctcgatct ggacacgaac agacaggtaa aagaccttat
      361 attgttttaa gtcatgatat tattgcggat tatagtaacg ttgttacagt tgctccaatt
      421 tctagtacaa ctagaaacta tccgctatat gtaaatataa actcagaata tgaaatgaag
      481 acaacaggaa aagtattatt agatcaacta acgacaattg attatgaagc cagagagtgt
      541 atttttttgg aaaaagcgca tgatagttta gttgaggagt tattgatgaa agttagaaca
      601 gtttttcaaa aagtaagcaa ataaaataga aacagcagca tgatcaacta ttcgtgattg
      661 accatgctgt ctttttttat tctatatacg gtttgtctcg taacattgta gtcttttgca
      721 atcttagcga tcgcaacacc tttttttaga tcctcaacga tgtttttata aacaagacga
      781 cgttggggat cttttgcatt ggcactgtat agcttaggac gtcctttata aacaccgttc
      841 gcttttgcaa tcttaatgcc ttgtgcctga cgtcgtttag attcggtacg ttcttgttca
      901 gcgatcatgg ccaaaatttg aatgatcaaa tctttaatga atttatccag gagaggattg
      961 ccaattgctt cggccatgat cggtagactt gtgatgatca gctgcacatt tttcttcttc
     1021 aagtaattga ctgaagcgat gatctcgtcg taatttcttc caagtcgatc aatagcttcc
     1081 acaataaaaa tatcttgatc tcggacgaaa tccagtgctt cttgaaaaac aagtcgatga
     1141 gtaatcgttg cgccagattg tttctcaatg aaaattctct ctgcaccgaa ttttttcatt
     1201 tcttcaatct gccgttgttc attttgatcg atggatgaga cacgtatgta tgcaactctc
     1261 aaaattttta cctactttct gcaactattt aaaaaacacc ctaatcatac acgagaaaac
     1321 cagatttttc aatgtcgcgg tcgtgtctag ttagggtata ccttatatag acaaaaacta
     1381 atgatggagg aaatagtatg tgtcactttt ctttttaaat ggcaatattt tttgtaaata
     1441 aatgtcaatc aagaaaattt aaacgattat gacattaaaa atatatttta tgaattttct
     1501 agtatataac ttgatttatc tgttaagatt tattaagaaa acgttttctt atttttgatt
     1561 tcgaggtgat agacaatgaa aaataagttt attttatctt taggtatttt aactattgga
     1621 attagtgtaa ctggaactac aattcctaca tttgctgata gtacaaatga accaactact
     1681 gtagtagata ataaccaaga attaactcct ttagatagga acggaatagc cattggtaac
     1741 ccaactaacg acttaactgt tactgaaaat tatttaatag tttctccatt acttgctcga
     1801 gcagcttcta aaacgatacg agtgacagga acgatgattt ttgataaagt tggttggcct
     1861 tctagacctc ctcaatcacg gaattggaaa gaaaaaagaa atggttattg gtactatgga
     1921 aaattgtatt tacaaagtta taaatcagct ggaaacaatt ggattgcgac ttattcagga
     1981 accttaacta gaaagtaggg attttttatg ccagaatttg tgaacacacc aaatttttat
     2041 caagatagcg atattctaag taaaattaat ttaccgaaag aagaatcagc tttacaagtt
     2101 cagcgaactt tacaggagac acaaaaaatt caaaaatcaa tttctaatct agaagattct
     2161 gaagaaaaaa gaaaaaaaag agaccaaaaa acatatcaaa aagaaaaata atgattttaa
     2221 aaaaagagtg tctagtcgac attctttttt tctaattgaa agtgttcata aaatcaccca
     2281 tttctggaca ctttcttttt ttgctttatt tttcaaaaaa acaattcatt tcatgttcat
     2341 aaacccataa caatatctat gttcagttaa actatatgga taaagttatg ttacaataaa
     2401 attaatgaag gagtgatttt tttgaaaata ggatacgccc gggtatctac tggtttacaa
     2461 aatttggatt tacaagaaga cagcctaaat aaatttggtt gtgaaaaaat ttttactgat
     2521 catatgagtg gggcaaaaag taatcgacca ggattagaaa tggccattga ttttgttcgc
     2581 tctggcgata cacttgtcgt ttggcgctta gatcgtttag gtagaaatat ggaagatttg
     2641 atttcaatcg tcaatcgact gaatgagcgt ggtgtgagtt ttcatagtat tcaagaaaat
     2701 attacgatgg acaaatcaag ttctacagga cagctcatgt ttcatttgtt tgcggcattt
     2761 gcagaatttg agcgtaattt gatcctggaa cgatccgcag caggacgagc agctgctcgt
     2821 gcaagaggac ggtttggtgg tcgtcctgaa aaattgtctg aacaagattt ggaattactg
     2881 aagactttag tggatagcgg tacacctatt aagactattg cggaacggtg gaacgtctca
     2941 agaaccacca tttatcgtta tttggcaaaa atggaggaga aaaatggaaa gacaaattct
     3001 cattagtttt tgtcatttaa tgctgaaaat ttttgccatt tatctagaaa agtgacaata
     3061 gtatgagaat tttttgtaag tgtctactga taacttattc tcaaatgttg taaggatttt
     3121 attcatttgt taatattaa
//
LOCUS       DACDAF010000150         3130 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.159, whole genome shotgun sequence.
ACCESSION   DACDAF010000150 DACDAF010000000
VERSION     DACDAF010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3130)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3130)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3130
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.159"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..419)
                     /locus_tag="IVZ69_002683"
     CDS             complement(<1..419)
                     /locus_tag="IVZ69_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184698.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIVEGRIIQCYVDENRAKQRLRIYYAKTSVIGNTIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITASQAWQNAKTLAKPVIPS"
     gene            complement(429..1166)
                     /locus_tag="IVZ69_002684"
     CDS             complement(429..1166)
                     /locus_tag="IVZ69_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP8184699.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDVEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFNLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            complement(1217..>3130)
                     /locus_tag="IVZ69_002685"
     CDS             complement(1217..>3130)
                     /locus_tag="IVZ69_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP8184700.1"
                     /translation="TIWSALGEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQ
                     ELNGKIAELKDSLAPIGNTIIDALEPVIDFLGKMADAFNNLPQPVQDFIVAIGGLTAA
                     FGILLPAILAVSYLFGPMMLIIGGIIAVIAGVIVAIKNWGAITDWFSGLWKKFTDWLG
                     DTWESIKDGASSVWDGVKETWSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQ
                     ETWQTFVDWVSNIWNGVKEVWSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAG
                     QLLGAAWQAVWTPISDFLKNTWDTMTQWISIAWNGIVTTFHTIFDPVVAWWNGIWTAI
                     STTASNIWNSISATASSIWNSIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISST
                     ASNIWNSVTSSISNAINAAKSAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISS
                     KVNDGKNAISSGWSNLTGIVSDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISSIFD
                     NLNISIPHIPLPHFKLSGEFNPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVL
                     PLKRSVLQEIGDRILSSTSVSSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDS
                     ITKVQNDNASAWR"
BASE COUNT          961 a          678 c          471 g         1020 t
ORIGIN      
        1 gaaggaataa ctggtttcgc taaagttttt gcgttttgcc atgcctgact agcagtgatc
       61 ttttctgttc cactgtcata tttattcaac accgattttc ttatatcatt gaaaataggt
      121 tcagctttta cttctatcgt attgcctatt acagaagtct ttgcataata aatccgtaga
      181 cgctgttttg ctcgattttc atctacataa cactgaataa tacgtccttc tacaatcaaa
      241 tctgcattag ttccgcttat tggataagta ccctgaaata tctcggctcc gtttaattta
      301 ttgctaacag tagctgttaa ccagtctgac aaagcgccta aaccttgcgt atcatataaa
      361 tgttcagcta aattattcgc gtcgttttta tcgtaaatag ttattaaatt atcgatcatc
      421 tatttcacct accttaaccc attacgataa atttgtattt tgctcaaacc agtacaatta
      481 aaataattaa tatccacttg caatgtcgga tattgcatgg tcttcatttt gttggaccga
      541 tctaaaatat ctccgtccga ttgctcttcg tagcaaagca tcaaatcact atcaatgact
      601 acgtcagttc ctactactaa gccttcaaaa ctaaacacat aatcatttaa gatgaactgg
      661 catgaagtag ctgaaggagt gatgataatc tttggaaaac tttcttctaa actattattc
      721 agcaagttaa atgactgtgg tttatctacg gttataggta catcttcttg aactcttgcg
      781 aatggtttcg cagtaatatt tacatcgaac tctccccatt caacaatatc gttttctgca
      841 tccccaatat cgatagtctg gataacataa tagacgttgg gatcatcaga gaattctaat
      901 ttctttgcat aatttaacca atgacgcatg atataaaacg attgcttgaa cgcttgatgg
      961 tcttccacat cctctaaata gttatagtgc aatgtaaacg acatgtcttc aaacgagtaa
     1021 tcttgtacta agccacctaa ccttcctaaa acagaagttt caactctctg tctttttgga
     1081 gaaggtatgg ttggtctttc agctaaagcc aatttatgca aataatcagg aaatccatcg
     1141 attatagaat gtatacaatc agtcattttt tcacatcctt tttaatacta aaaaaacagg
     1201 agaaatactc tcctgtttaa cgccatgccg aagcattatc attttgaact tttgtaatgc
     1261 tatcaatgat ttgttgagtt gtttgcttca tagtaacctc atctgcgtta ccatcaattg
     1321 tgaaattgaa ttcgtagtta ttcacaggtt gaatcgtttg tgccctagat gaaactgatg
     1381 tgctactcaa gatacgatca ccaatttctt gcagcacaga tcttttcaaa ggtaaaactg
     1441 cttcaggtcc tgcttcgccg acaccgataa tattcggaga attaaacaca ctacctttcg
     1501 cataccaatc aacacccaac gttgggattt tccccttcaa tggattgaat tctccgctca
     1561 atttaaaatg tggtaacgga atatgtggta tagaaatatt caaattatca aagatactac
     1621 tgattttatc tctgatccaa tcaattggag cgctaacagt ctttttgata ccttcccaaa
     1681 tgttagcaat tgtactttta acattattga atatgtcgga aacaatacct gttagattgg
     1741 accaaccgct tgaaattgca ttttttccat cgtttacttt agagctaata gtgcttgtaa
     1801 ttccattcca aagattcaaa gcagtatttt tgataccgtt ccaaattccg ctgatccacg
     1861 aagatatact attccaaaca ctttgaatgg cacttttagc tgcgtttata gcattgctta
     1921 tactactagt cacgctattc cagatatttg atgctgtaga gctgattgaa ttccaaattc
     1981 cacctaacca actagataca gttgaccaaa tattttgaat tactgtagca gctgcttgta
     2041 ccaagctagt gattgtattc ttgatactgt tccaaatact agaagctgtt gcactaattg
     2101 aattccaaat atttgaagcc gtagtactaa tagctgtcca tataccattc caccatgcca
     2161 ctactggatc aaatatagta tggaatgtag ttacaatccc attccaagcg atacttatcc
     2221 attgtgtcat agtatcccaa gtatttttaa ggaaatcaga aataggtgtc caaacagctt
     2281 gccaagctgc gcccaataac tgtccagcta catcaaaaat acccacgata atattaatac
     2341 cagcttgaat caatgacgtt attaatgtcc atggtatttg aacaattcct acaatgtctg
     2401 cccaaataat cgaccatact tctttgactc cgttccaaat atttgaaacc caatcaacga
     2461 atgtttgcca agtttcttgg actccttgcc agatgttgga agctccttca actaatccgc
     2521 tccatagctc tccaaaccaa tcagaaactc cttgccaaat atcttgaacc caatctacaa
     2581 atccagacca ggtttcttta accccatccc aaactgatga ggctccgtct tttatacttt
     2641 cccaagtatc acccaaccaa tcagtaaatt ttttccataa accactaaac cagtcagtaa
     2701 ttgcacccca gttcttaatt gccacaataa cgcctgctat aacagctata attcctccaa
     2761 ttataagcat catcggacca aataaatatg acacggctag tattgccggt aacagtatgc
     2821 caaatgctgc tgtaagacca cctatagcaa caatgaaatc ctgtactggt tgtggaagat
     2881 tattaaacgc atcagccatc tttcctagaa aatcaattac tggttcgagt gcatctatga
     2941 ttgtgttgcc tataggagct aatgaatcct ttaattcagc tattttcccg ttcaactctt
     3001 gcaacggagt agtagaatct tcattcattt tttgtgcaga tccactaaca tcatcaaatg
     3061 tatggttaac atcagttaaa gattggacaa ctttcatcgc attatcttcg ccaagcgcag
     3121 accaaattgt
//
LOCUS       DACDAF010000151         3020 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.160, whole genome shotgun sequence.
ACCESSION   DACDAF010000151 DACDAF010000000
VERSION     DACDAF010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3020
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.160"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            89..826
                     /locus_tag="IVZ69_002686"
     CDS             89..826
                     /locus_tag="IVZ69_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HAP8184701.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            840..1655
                     /locus_tag="IVZ69_002687"
     CDS             840..1655
                     /locus_tag="IVZ69_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HAP8184702.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            1668..2315
                     /locus_tag="IVZ69_002688"
     CDS             1668..2315
                     /locus_tag="IVZ69_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP8184703.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSTLAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            2331..2987
                     /locus_tag="IVZ69_002689"
     CDS             2331..2987
                     /locus_tag="IVZ69_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HAP8184704.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
BASE COUNT          956 a          502 c          637 g          925 t
ORIGIN      
        1 ttacaaatta ctaaactatc agatataatg tattttatta tacatcttta aaagaaatct
       61 tactaaataa taatgggagt gtaattctat ggcaatgatt aaatttgatc acgtggataa
      121 atattatggc aagttccacg cattaaaaaa tatcaatctc gaattcgaga aaggagaagt
      181 tgtcgttgtc attggtcctt ctggttcagg aaagagcacg atgcttcgct gtatcaatgg
      241 attagagacg atctcttcag gtaagctgct gattaatgat actgacttgc atgataaaaa
      301 gacaaaactg acagaagtcc gaaaaaacat cggcatggtt ttccaacatt tcaatttgta
      361 cccaaataaa actgttctgg aaaacatcaa attagcacca atcaaagtgt tgaagcaaga
      421 ccaggcaact gcagtcaaaa acgcggagaa atttttgaaa actgtcaata tgttagataa
      481 gaaagattct tatccttcca tgttatccgg gggacaacag caacgggtgg caatcgccag
      541 aggtttagcg atgaatcctg agatgctgct gtttgatgaa cctacttctg ctttggatcc
      601 ggaaatgatt ggtgatgtat tagacgttat gaaaaaattg gctcatgacg gtatgtcaat
      661 gattgtcgtg acacatgaaa tgggctttgc caaagaagtg gcggatcgtg ttatcttcat
      721 ggctgatgga gaagtattgg aagacagcag aaatgtgaga gactttttcg aaaatccaaa
      781 tgaagtccga gcacagcaat ttatcagtaa agttatcaat cattgatagg aggaaaaaga
      841 tgcgcaggtt aaaaaaaata cgcctgattt tccttttagg cattgctttt cttgcactag
      901 ccggatgtaa aggaaatggg ttggcaaatg aagatatttt agagcgaagc aaatctacca
      961 atgaaatcat ctggggtgtc aagtatgata ctcgattatt tggaatgatg gatattgaga
     1021 gcagaactgt acaaggattt gatgtagata ttgcaaaagc aatcactaaa aagatccttg
     1081 gtgacaatgg aaaaacagaa tttgttgaag tcacttctaa aactcggatt ccattattga
     1141 aaaacggaaa tatcgatgca attattgcaa cgatgacgat cacagatgaa cgaaaaaaac
     1201 aggttgactt ttcagatgtc tatttcgatg ctggccaagc tttgttggta aagaaaggaa
     1261 gccaaatcaa aagtgtagat gatttgaatg cttctacaac ggttctagca gtcaaaggtt
     1321 ctacatcggc tgcgaatatc cgacagcatg caccagatgc aaaaatttta gaattagaaa
     1381 actatgcaga agcatttact gctttacaat ctggtcaggg agacgcgatg actacggata
     1441 atgcgatttt gttagggatt gcagatgaaa atccagagta tgagttagtt ggtggaacgt
     1501 ttactaatga gccttacggg attgcgatca acaaagggca agaaaacttc ttgaaagctg
     1561 ttaaccaagc gctagaggaa atgcatgcag atggcacata cgataaaatc tatcaaaaat
     1621 ggtttccaaa tgaaactgaa ggaaaagtag agtaaggggg agaggcaatg agcgaattga
     1681 tacaaactta tggaccaatc tttgtcgacg ggttcaagat cacattgttt tcgagtgtct
     1741 tagcacttgt gtttagtttg attatcggaa cgttaatggc aatcttccaa ttatcaaaga
     1801 ataaagtagt gagcacctta gcaaaggcat atgtagaatt ttttagaaac attccattat
     1861 taatcatcgt gatgtttttt tatgttgtcg taccgattta ttggtttaat ctagatggat
     1921 tccaagcagg tacgattgga ttaacgatct atacatctgc ttttattgct gaaacagtac
     1981 gttcagggat tcaaaccgta ccaaaaggtc aaacagaagc aggactatct tctggtttta
     2041 cctattcaga aatcatgcgt tatattgttt taccgcaagc attcaaaatc gttatcccgc
     2101 cattaggcaa ccaatttatc aacctcgtaa aaaactcatc tattttagca atcgtagctg
     2161 gtttagattt gatgtatcaa ggagacttga tcgctagtga aacattcaat accttcgata
     2221 cgtatatcat cgttgggtta ttttacttag ttatcacgct accgttatct tacttaatgg
     2281 tttatcttga gaaaaaatgg gcggttcgtt catagaagga ggggaaatac atggatttta
     2341 gcggcgcttt ttcatggatg aatatccgtt ttttattgga aggattaaag gttactgttg
     2401 aagtttcatt gttttcgatc atttttagtt tcttgatcgg tggtctgaca ggtgtgattc
     2461 gttttgcgaa tatccctttc ttttccaaaa tccttggtgt agtgattgat attatacgga
     2521 atcttccatt attattgatc attttcttca cttactttgc cttacctcaa atcggcattc
     2581 agatgaacat cttctggtcc gctgtcgcag cattaacgat ttttgagtca gctatgttgt
     2641 cggaaatttt ccgagctgga ctcaatgctg ttccaaaagg acagatggaa gcaggattat
     2701 caacgggact gacttatgta gaatcgatgc gaacgatcgt gttaccgcaa gcatttaaat
     2761 caatgatccc ggcaattgtg agccaattga tttcactgat caaagatact tcattagcag
     2821 taatcatttc tttacctgaa ctttctcatc aggcacgtat tatttatgga cagaacacca
     2881 attatgtgct tccgatgttc atcatcatga cacttatgta cttcgtggta tgttacgcgc
     2941 tttctctgct ttccggttac ttggaaaaga gacggtacag ttattaatag atgattcttt
     3001 tagcggttgt ggcaaactaa
//
LOCUS       DACDAF010000152         3011 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.161, whole genome shotgun sequence.
ACCESSION   DACDAF010000152 DACDAF010000000
VERSION     DACDAF010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3011
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.161"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(65..1285)
                     /locus_tag="IVZ69_002690"
     CDS             complement(65..1285)
                     /locus_tag="IVZ69_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP8184705.1"
                     /translation="MKLIGIVGSAAELSYNRKLLTFIQKQYHELFNLEIIEIKDLPLF
                     NQDDDQTNSPAIQQLNRKILMADGVIIATPEHNHTVPAGLKSALEWLSFKIHPLENKP
                     VMVVGASYYDQGTSRAQLHLRQILDAPGVNALVMPGNEFLLGKAKEAFDQEDRLIDPR
                     TVDFLGSTLASFVKFIKVVSTLAGPKKLPPEDLHATGTIATTIPDVDMSDDHWLEKAS
                     EAVGAVSGNTYVKLNRGLLTVDQINYFLDSMPMELTFADNNNQFLYYNLRQEAKEMLA
                     ARVPGQVGNPLANCHPEKSYKNVEWVIQQLRSGATDAVRVHVPKQVPEKYIVHNYQAM
                     HDENGEYAGINEYILDFKPIIEWYLQQTGQQLVGNEDAVSSASVHGGKTDAVTSASTH
                     DETAVDAVSSASVK"
     gene            complement(1305..1910)
                     /locus_tag="IVZ69_002691"
     CDS             complement(1305..1910)
                     /locus_tag="IVZ69_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005234653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HAP8184706.1"
                     /translation="MKFIGLVGTNSTRSTNRELLQFMKNYFVNEAEIEIVEIKELPLF
                     NKPENTELPNVVKEIAGKIEQADGVIISTPEYDHAVPASLINALNWLSYGIFPFVDKP
                     VMITGASYGTLGSSRAQAHLRQILDSPELKARIMPSSEFLLGHSLQAFDEQGRLIDEE
                     QVAKLRELFKDFLLFVTITSQLQHAHQANKREAESFSWETI"
     gene            complement(1959..2891)
                     /locus_tag="IVZ69_002692"
     CDS             complement(1959..2891)
                     /locus_tag="IVZ69_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HAP8184707.1"
                     /translation="MNQVIEETKIWQMMGTTITLQVGHEEPSRLLAELGEWLHVYEHR
                     FSAHDATSELMAINQAAGRQAVIVHPELFELIKLGKAHSCARNSYLNIAIGPVVQKWH
                     IGFEDALVPTKAEITELLLLTDPHQIQLDEKMKTVFLTKPGMMIDLGALAKGYIADKL
                     ITHCRERNAAFALVNLGGNIVVFGESPRRSDGAWRIGLRNPKGSREESLAVVKLNNQS
                     LVTSGIYERYLQNGSSVYHHIIDPKTGFPVKNDVASLTILSDSSVDGEIWTTRLFGAS
                     SLEVLKALEEQPGIEGAVVTKENQFLYTKGFEKI"
BASE COUNT          827 a          628 c          522 g         1034 t
ORIGIN      
        1 agcttaaatc atagataccg taagggactt tattctttat ttaaaacttt gcaacagaac
       61 ctttttattt tacagaagca ctcgaaactg catctactgc agtttcatcg tgtgtgctgg
      121 cgctggttac tgcatctgtt tttccaccat gaacagatgc acttgaaacc gcatcttcat
      181 ttccaacaag ttgttgaccc gtttgttgta aataccactc aatgattggt ttgaaatcaa
      241 gaatgtattc attgattcca gcatactctc cattttcatc atgcattgct tggtaattat
      301 gcacaatata tttttctggc acttgttttg gtacatgaac acgtaccgca tctgttgctc
      361 cgcttcgcag ttgttgaatt acccactcta catttttata cgatttttct gggtgacagt
      421 tggctaatgg attccctacc tgaccgggca cacgagcagc taacatctct ttcgcttctt
      481 ggcgcaaatt ataatataaa aattggttat tattatctgc aaaagttaat tccatcggca
      541 tcgaatctaa aaagtaattg atttgatcca ctgtcaataa cccacgattt aatttgacgt
      601 aagtatttcc agaaacggca ccgactgctt cagaagcttt ttccaaccaa tgatcatctg
      661 acatatcaac atcgggtatt gtcgtagcaa ttgttcctgt cgcatgcaaa tcttctggtg
      721 gaagcttttt aggccctgct aaggtagaca cgactttaat gaattttaca aaacttgcta
      781 atgtactgcc taaaaagtca acagttcgtg gatcaatcaa gcgatcttct tggtcaaatg
      841 cttcttttgc ttttcccaat aaaaattcat ttccgggcat cactaatgca ttcacgcctg
      901 gtgcgtccaa aatttggcgc aagtgtaatt gcgcgcgtga agttccttga tcgtagtaag
      961 aagcacccac aaccattaca ggtttatttt caagtggatg gattttaaat gatagccatt
     1021 caagtgcact tttcaatcct gctggaaccg tatgattgtg ttctggcgta gcaataatta
     1081 ccccatcagc cattaagatt ttgcgattta gctgttgaat agcaggacta tttgtttgat
     1141 catcatcttg attgaacaga ggtaaatctt tgatttcaat gatttctaaa ttaaatagtt
     1201 catgatattg tttttggata aatgttaata atttacggtt atatgaaagt tcagctgctg
     1261 atccgacgat acctattaat ttcatctttg tttgctcccc tcgattaaat cgtttcccat
     1321 gaaaagcttt cggcttcacg tttatttgct tggtgcgcat gttgcaattg actagtgatt
     1381 gtgacaaaga gtaagaaatc tttgaatagt tcacgtaatt ttgcgacttg ttcttcatca
     1441 atgagtcgtc cttgctcatc aaaggcttgg agtgaatgac ccaataaaaa ttctgagctt
     1501 ggcataattc gtgcctttaa ctctggtgaa tccaatattt ggcgcaaatg tgcttgtgcg
     1561 cgtgaagaac ctaacgtgcc ataagacgct ccggtaatca tcactggttt atccacaaac
     1621 ggaaaaatac catatgaaag ccaatttaat gcgttaatca atgaagcagg aaccgcatgg
     1681 tcatactctg gtgtgctgat gattacgcca tctgcttgtt caatttttcc agcaatttct
     1741 ttaacaacat ttggtagttc tgtgttttca ggtttgttaa atagtggcag ctccttgatt
     1801 tcgacaattt cgatttctgc ctcatttaca aaataatttt tcataaactg taataattca
     1861 cggtttgttg accgcgttga atttgttcct actaatccaa taaatttcat cttcattctc
     1921 tttcctttct aacatcgatt tctgactgtt cgcacgtact aaattttttc aaatcctttt
     1981 gtatacaaga attgattctc ttttgttaca actgctccct cgatacccgg ctgttcttca
     2041 agcgctttca acacttctaa agaagatgct ccaaataaac gtgtagtcca gatttctcca
     2101 tctacagaag aatcagacaa aatcgtcagg cttgctacgt catttttaac tggaaagcca
     2161 gttttcggat caatgatgtg atgatacact gacgaaccat tttgtagata acgttcgtag
     2221 attccagagg taactaaaga ttggttgttt agtttaacca ccgcaagcga ctcttcacgt
     2281 gaacctttag gatttcgcaa accaatacgc caagcaccat ccgaacgtct tggtgattca
     2341 ccaaaaacaa cgatatttcc tcctaagtta actaaagcaa acgctgcatt tcgctctcgg
     2401 caatgtgtaa ttaatttatc tgcaatgtaa ccttttgcta acgcccccaa gtcaatcatc
     2461 attcctggtt tggttaaaaa aacggttttc attttttcat ctaattgaat ttggtgtgga
     2521 tccgttagca gaagtaactc agttatctct gcttttgttg gaaccaatgc atcttcaaat
     2581 ccaatgtgcc atttttgtac aaccggacca atagcaatat tcagataact atttcttgca
     2641 caactatgtg cttttcctaa tttgatgagc tcaaaaagtt caggatgtac aatcacagct
     2701 tgtcgtccag cagcttgatt gatggccatt aattcagaag ttgcatcatg tgcgctgaag
     2761 cgatgttcat aaacgtgcaa ccattcgcct aactctgcta gtaatcgact aggctcttca
     2821 tgcccaactt gtaatgtaat tgttgtcccc atcatttgcc agattttcgt ttcttcgatc
     2881 acctgattca ttttgtacct tctttacttg aactacggat tacatgagta attagttttt
     2941 atttttgtta ctgttttcac aaccagatga tacgcctgct agatttattt gtcaaccgat
     3001 tttatatatt t
//
LOCUS       DACDAF010000153         3009 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.162, whole genome shotgun sequence.
ACCESSION   DACDAF010000153 DACDAF010000000
VERSION     DACDAF010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.162"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..482
                     /locus_tag="IVZ69_002693"
     CDS             <1..482
                     /locus_tag="IVZ69_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HAP8184708.1"
                     /translation="LTYRTEDEDSIRYFVLFTGFEINKTKKFVEVSVNPDLEYIINGL
                     TAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYYVVRIEEFRSLMDIPEYYQMGNI
                     DQKVLNPALRELKKYFNDLKVTKIKAKKGNKIAKLEFTFSSLTSDLPKISLRNWLEE"
     gene            complement(619..1035)
                     /locus_tag="IVZ69_002694"
     CDS             complement(619..1035)
                     /locus_tag="IVZ69_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184709.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(1038..1322)
                     /locus_tag="IVZ69_002695"
     CDS             complement(1038..1322)
                     /locus_tag="IVZ69_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184710.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            complement(2022..2117)
                     /locus_tag="IVZ69_002696"
     CDS             complement(2022..2117)
                     /locus_tag="IVZ69_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HAP8184711.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            2770..>3009
                     /locus_tag="IVZ69_002697"
     CDS             2770..>3009
                     /locus_tag="IVZ69_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HAP8184712.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLN"
BASE COUNT          958 a          478 c          565 g         1008 t
ORIGIN      
        1 atcttactta ccgtactgaa gatgaggatt ctattcgcta ctttgttttg tttactggtt
       61 ttgaaatcaa taaaacaaaa aagtttgttg aagtcagtgt taatccggac ctagaatata
      121 ttattaatgg tttaacagct gaatttagta gatttgaatt atctgctttc acgtcgttgc
      181 gttctacgta tgcaaaaact ctattccgac tgcttatgca gtaccgttct actggttatt
      241 atgtagttcg tattgaagag tttaggagct taatggatat cccagaatac tatcaaatgg
      301 gtaacattga tcaaaaagta ttaaatcctg cattacgaga actaaaaaaa tacttcaatg
      361 atcttaaagt cacaaaaata aaagcaaaaa agggcaataa aatcgccaaa ttagaattta
      421 ctttttcaag cctaacgtca gatttgccaa agatttctct gcgtaactgg ttagaagaat
      481 aaataaaaaa gaactcgccc cccttacatt aagcaagtag acaagtccct tacaaccgac
      541 taagattgct agtacattct agcatattgt atggggcttc taaataaaaa acagatagga
      601 ataactccta tctgtttttt atcgttttag aaaatttgtt gggtcgaaat ttctagaagt
      661 gactgtttga ctggtttctt tttgatgatt ctttggtcga tttcgatttg atggatttag
      721 tttagcttcg attttttctt tcacttcttg atatacttta gaatttgtgc caataagaac
      781 gcctgtatct tttagatata aatcagcaaa ttctgcgatg atttcagtca tgatggaaat
      841 ttcttttccc atagcattta gttttgcctg attgctggta gtggtcgtgt tggtatcggg
      901 ttcataactc atacataaaa agcgaatggc ttccgagtag ttattgatat ctggattttt
      961 ttcgatgatg gaatctaaaa cgtcaacatg actagggtac aaagtaacat gtttttggac
     1021 agaagttttt ctcatggtta tatcattcct ccgataagca tttcaatgat ttgattattt
     1081 gtgtagacat actcgcttaa tatttgagta ttttctgttt ggatagcaat aaatttatcg
     1141 agcaataaat cgaattggtc ttttttgtaa gtcgtaagtt gacggtcaaa atcactttcg
     1201 attaaaactt ttagatattt atttcgactc catttttctc ctgttttatt cgtgagttct
     1261 tggcaacgtt tgtctattgt tgcaacaaac tttggatcaa tattccgaac taaaatgtcc
     1321 ataaaaaatc tccttttgca attatgtata atttatgtat accatacaaa tactatattt
     1381 gtatagctgt tttttgccaa aatgctatac ataagctacc cacgatggcg aaaaagtgat
     1441 atcaaatttt tttctgagaa acgtgatagg cacagcctat ctacccactt tttttagaaa
     1501 gtgggtacac gtttccttat gctctttaaa attcgggggg gagtgctgca cgtgtaatcg
     1561 ataaccaaat ttaacagacg aaaaattgtt ggaatataaa aatatgacac ccgaaagaaa
     1621 acgatcgttg gaaaaattaa tgcaactagt gaacgaagac ggcggaattt cagacgcagc
     1681 ttttgacgca tggagcgaat ttcatggaga atataattaa gtgggtttaa atggctctaa
     1741 aatcgcttct aagagttttt tagcttggac caatgaaata caccaaaaac taaataaaac
     1801 gtcttaaatc gaaaaatacg agctctcaga gcgactttat ttgtaaatgt tgcatataag
     1861 aaataattac ggattttaga cttttgtagg atatttttga aataaatatt tatttctgtt
     1921 ataatttgat tgcaaataag tgaacacgaa acacacgaaa tccccagaga ggtcggattc
     1981 tctggggctt tttttgtggg ctgagtcgcc ttaattaagt tttacttctt gtttcggtta
     2041 ttcaaccagt aactgaacaa agcgcttaaa agcccaacaa gaagggagca aataaagtta
     2101 gtgaacacga aacacacctc cttccagtcg caagactgtc ggataggcga caatcaatta
     2161 tacaataaaa aagcaaaaat aagcctaagt tttttattgc cttggggttg ttagggcttg
     2221 ccctgaccgc ctgtaaggcg ctttagaacg aaggacatag tttttatcga atcttgtctt
     2281 agaacggctt agacgagctc tcaggacgcc acaaaggagt ccctaatgaa ttatttttgg
     2341 cgaaggagcc taaaggcgac tgctgcaagt aaaatgtgag agcgtagcga tcactccttc
     2401 ttacagcgac catagggagc tagattggca gtttaatatc atgcgcgaac ctgtttattt
     2461 taaaaagtgg gtgatttttt ggcgggaaat tttgctcgcg cgcgcgcgtt tattttattt
     2521 attttttaaa gattttttag aacccttttt agggggcagt tgagccttac tctcccaacg
     2581 gatacagaag ggtactaaca actttttatc tgagtactaa caacttttta tctgagtact
     2641 aacaactttt tatctgagta ctaacaactt tttatctgag tactaatatc cttttgtata
     2701 ataacaacca acctatttac gagttggttg ttaaaggtta ttatttattt gtaagggggg
     2761 aagaaaggaa tggatgaaaa aacggaatta acagtcaaat atcaaaatga attgaattta
     2821 gtaccgctga aaaatttcaa tgctaagcag atggatttat tttttgcatt atgcgctcgt
     2881 atgaaagatc gtggtttgaa aaaagttaga ttttctttcg aggaattaaa agagttaagt
     2941 gattataaga tgactgctac aaaagccttt gtcggtgatt tagaaaagct ctataaagat
     3001 atgcttaat
//
LOCUS       DACDAF010000154         2892 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.163, whole genome shotgun sequence.
ACCESSION   DACDAF010000154 DACDAF010000000
VERSION     DACDAF010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.163"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            122..736
                     /locus_tag="IVZ69_002698"
                     /pseudo
     CDS             122..736
                     /locus_tag="IVZ69_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337511.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(1106..2107)
                     /locus_tag="IVZ69_002699"
     CDS             complement(1106..2107)
                     /locus_tag="IVZ69_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4062 domain-containing protein"
                     /protein_id="HAP8184713.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYINNSSGQSVINKQIVENSDILLAIFGHKLGSPVDNYRSGTIAEIDY
                     FYKNSKGEVGVFFLDEPVPQVLAEEYIEVKKYRDSLEDKGFYGTYSKDNIRRFLTKKV
                     NYLIEKAQNNLESKRFDLDSISYKTPSVINKKVTGTDKDFDDNLDIFDPIEFDNDERL
                     LLIYAFMDENSIFSTDNSTYRKVVQWESDNNLRSYLSDRVFDVLEKLSKSGILKEEYD
                     SSFDEYPSRYILISEDYKKFKRYFLKNEKKISVIMEKYKAPIQADPFSNLDESDLPF"
     gene            complement(2266..2532)
                     /locus_tag="IVZ69_002700"
     CDS             complement(2266..2532)
                     /locus_tag="IVZ69_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184714.1"
                     /translation="MMIKKLIEEKQKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            complement(2522..2878)
                     /locus_tag="IVZ69_002701"
     CDS             complement(2522..2878)
                     /locus_tag="IVZ69_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP8184715.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVVNGRYVITHGFTKKTEKTPISE
                     LKHAKELREEWFTNDD"
BASE COUNT          926 a          517 c          395 g         1054 t
ORIGIN      
        1 aaaaaccgtt tgtctattta gagtttaccc taaatagaca aaaatataac attgaaaaat
       61 ttagagttct aacgtatgat tagggtgtat tataaacgtt atagaaaagt agggaataaa
      121 tttgaaaatt gcttatatta gagtttcatc catcgatcaa aatgaacaac gtcaaattga
      181 agaaatgaaa aagtttggcg ctgaaaaaat ttttatcgaa aaacaatctg gagcgacgat
      241 tagtcatcgg ccgattttcc aggaagcttt agattttgtc agagagcaag atatttttat
      301 tgtagaagcc attgatcgac ttggacgcaa ttatgacgag attatcgatt cagtgaatta
      361 tctaaagaag aagaatgtgc gacttattat caccagttta ccgatcatgg ctgaagcaat
      421 tggaaatcct ctcctagata aattcatcaa agacttaatc atttaaatct cagccatgat
      481 tgctgaacaa gaacgtactg aatcgaaacg acgccaggca caaggaatta aaatcgctaa
      541 agcaaacggc gtctataaag gtcgtcctaa gttatacagt gcagacacca aagatcctca
      601 acgtcgcctt gtctatagga gtatcgttca ggatcttgag aatggggttg ctatctcaaa
      661 gattgcaaca gactacaatg tgactaggca aacaatttac cgaataaaaa aagaaatcga
      721 ccaactaatt gtatgatttc ttttttgaat cacgtaatta ttaattagct ttgtcatcaa
      781 tacagacaat cattttagat tcatctagct aagttgatta catttatgtt aaaaagaatt
      841 tagttaacat aaatataatt gatgcataaa tcgtccttat ttaaaggcat ttaacattga
      901 caacttagta taatgtatct tatgtaaact aataagattt gaattttatt ttatacacac
      961 tcgataatag atcaatttta tggtcccccg catttacgat tgcacaagag aaacataaag
     1021 tcgacctatt agcatttctt ttcaattcaa acattaaaaa agtttatacc tctgctacta
     1081 aaaaatgaaa ttatctattt aaaatttaaa acggtaaatc tgattcatcc aaattggaaa
     1141 atggatcagc ctgtattgga gctttgtatt tctccataat aacagatatc tttttttcat
     1201 tttttaaaaa atacctttta aatttcttat agtcctctga aatcaaaata tagcgtgatg
     1261 gatactcatc aaaagaagaa tcgtattctt cctttaaaat tcccgattta cttaattttt
     1321 ctagtacatc aaatactcta tcactcaagt aactccttaa attgttatca ctttcccatt
     1381 gaactacttt tctataagtt gaattatcag ttgaaaagat agaattttca tccataaacg
     1441 catatattag cagcaatctt tcatcattgt caaattctat tggatcaaaa atatctaagt
     1501 tgtcatcaaa atctttatca gttccggtaa cttttttgtt aattactgaa ggtgtcttgt
     1561 aagaaataga atctaaatca aagcgttttg attctaaatt attttgtgct ttctcaatta
     1621 aataattcac tttttttgtg agaaaccttc tgatattgtc tttgctatat gttccataaa
     1681 aacccttatc ttctaaagag tccctgtact tcttaacttc tatatactct tcagccaaaa
     1741 cttgtggaac tggttcatct aagaaaaaaa cccctacctc gcctttgcta tttttataaa
     1801 agtaatcaat ttctgctata gttcccgatc tataattatc aactggagaa cccaacttat
     1861 ggccaaaaat cgctaataat atatcactat tttctacaat ttgtttatta ataacacttt
     1921 gcccagagct attatttata taagtaggaa tcgcattcgt ttcccatcga attggcatca
     1981 aaattacttt tgtattatct gtattttcta tattccatct atatatggtt tcttctactt
     2041 cattcctctt tgctgctata tcacctggtg atgctataaa tacttttatt agatttatgg
     2101 ttttcattta ttgtaccttt ctctttatgt ctctttaaag taatttttgt ataaaattta
     2161 ttgactttta cactatagga caacttttat ctatttagta caaaaaggcc cactaaacta
     2221 attgattagt taggagccta ttacaggtat attttcaact cgcttttaag caaattctac
     2281 taccagcttt ttgcctaatg ccctagcgat atcatcaagt ttatcgaaag atacgttatc
     2341 ccctctctca attcgagcaa tagtagattg agttgtatgt gctttttgtg caagctccgc
     2401 ttgagttagg cctgcttcct cccgtgcatg ataaagagca accgcagttt cgagttttct
     2461 tccttcacgg tcatatgctt ctgcaaaatc tttgtctttt tgcttttctt caatcaattt
     2521 tttaatcatc atttgtgaac cactcctctc taagttcttt tgcatgttta agttcactta
     2581 ttggtgtttt ctccgttttt ttagtaaatc catgggtaat gacatacctt ccattgacca
     2641 catggaaata gatagctctt tggatgtttg atcctacctt acttcttaat tcgtacaaat
     2701 tagtgtctaa ttttttcacc catttcaacc gttgagctac tagcatccca ttcttttctg
     2761 tttcttctat tgtacgtaaa agcttcgcac tatctttttt tggtaatgtt tccaaccatt
     2821 ctaaaaattc atcatgacca ttaggtcttt taaatgtttc aaaagatatt ttttccatac
     2881 ccaattatat ca
//
LOCUS       DACDAF010000155         2889 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.164, whole genome shotgun sequence.
ACCESSION   DACDAF010000155 DACDAF010000000
VERSION     DACDAF010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2889)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2889)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2889
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.164"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            433..600
                     /locus_tag="IVZ69_002702"
     CDS             433..600
                     /locus_tag="IVZ69_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8184716.1"
                     /translation="MVYLNKKQTCEFLGIDNNTLDKWIRIYNFPVIKIDGIIRFDVED
                     IKGFMDTFKKI"
     gene            674..1900
                     /locus_tag="IVZ69_002703"
     CDS             674..1900
                     /locus_tag="IVZ69_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8184717.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFKEITGISSEKFQKTFPTRQLAIKA
                     ENEMKKKIAKVLREENANSLELKGQIKFKEFYKSKWLPRYELGQTTRSHKAPSDITII
                     NTKNLFRLHILPIFGEYAMSYLNANTEIISDELTKKSKEYANIKIIKCYVRSMFDIAE
                     VLNYIEFNRTTKIIQSITAPKKVALEEKRIREGKQALSSKELTDWLDAVRDDFNDQLL
                     SFHDYTLFMLTLYLGDRKSETYALQWKYIDFENQTVRLKYALDKHTKKKFTKGRKDTI
                     IQVPEIVMTLLQEWKSVQAEQLLKLKIKQTPDQYLFSYSKPSGEVNCPVHTDYLNYRI
                     NSIKKRHPHLVHLTPHKLRHTYATLARQGGADMNQISNALTHSGISTTKIYVNTPDLV
                     DKAVFEAFQRGLQKSN"
     gene            complement(2058..2675)
                     /locus_tag="IVZ69_002704"
     CDS             complement(2058..2675)
                     /locus_tag="IVZ69_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8184718.1"
                     /translation="MAKIGYARVSSLDQNLDRQLELLSECDKIFSDKASGKDTNREGF
                     QEMMKFIREGDIVVVTELKRLGRNNKELTETMNLIQLKKATLEVLNLPALTGITDDNL
                     RRLLNNLIIELYKYQAEEERRYIRETQQQGIALAKAKGKYKGGTLKYRENDPRLQLAF
                     NLFLTGSTDKEVEELTGINRRTFRRYRMKHGITNEVREQKNKSFS"
BASE COUNT          998 a          476 c          435 g          980 t
ORIGIN      
        1 attttaaatt tttacatacc tgtttatgaa aaactaaata atctgtcaaa aaaatatgat
       61 tgttcatttc taaatatgtt ttccaatttt aaaatctttt ttagcatttt tgtttccttt
      121 tcatatggtt tttcgttgtt aatagtgact aggatgatat tcctattttg accattgaca
      181 attaaatata atttttgaat aacgttccct gctattcgag ctaagaattc aagtacgcca
      241 tgacctattt agcgataact acttagagat ttctttttgt tttgggaaga caaaatgcca
      301 tgacaatagc agtagataat gatacttccg taaggctcgc cgtaaactgg ggagaggtga
      361 aattcctatg tgcttaccca agtcaattca aaaattttag ttcatttata aggggatgat
      421 tttattaaat caatagtcta tctaaacaaa aaacaaacct gtgagttttt aggaattgat
      481 aacaatactt tagataaatg gattcgtata tataattttc ccgtaataaa aatagacggt
      541 ataattcgct ttgatgtaga agatatcaaa ggctttatgg atacgttcaa aaagatttga
      601 attttacttt tgactgcata tactaaaagt agcgaaatat actgccttac ttttttatta
      661 aggagtgagg aagttgccta cgaagctttc aaatggaaaa tataaaacta atttgagata
      721 tccaaaaaaa tttaaagaaa ttacaggtat cagttcagaa aaattccaaa aaacatttcc
      781 aactaggcaa ttggctatta aagccgaaaa tgaaatgaaa aagaaaatcg caaaagtctt
      841 aagagaggag aatgcaaatt cattagagct caaaggtcaa ataaaattca aggagtttta
      901 taaatctaaa tggcttccta gatatgagtt agggcaaact actagatccc ataaagctcc
      961 aagcgatata accatcatta atacaaagaa tttatttcga ttgcatattc tgcctatatt
     1021 tggtgagtat gccatgagct atcttaatgc aaataccgaa ataatatcag atgaactcac
     1081 aaaaaagtcg aaggaatatg caaacataaa aatcattaaa tgctatgttc gttccatgtt
     1141 tgatattgca gaggttctaa attatattga atttaatcgt acaacaaaaa taattcaaag
     1201 tattactgca cctaagaaag ttgctctgga agaaaaaaga atacgagaag gaaaacaagc
     1261 tttatcttcg aaagaactca ctgattggtt agacgctgta agagatgatt tcaatgatca
     1321 attactttcc tttcacgatt acactctttt tatgcttact ttatatcttg gggatagaaa
     1381 gagtgagacc tatgctttgc aatggaaata cattgatttt gaaaaccaaa cagtccgtct
     1441 taaatatgcc ttggataaac acacaaaaaa gaaatttaca aaaggtcgaa aagatactat
     1501 tatccaagtt ccggaaattg taatgacact attgcaagaa tggaaatcag tgcaagctga
     1561 acaactattg aagttgaaaa ttaaacagac acctgaccaa tatcttttta gttactccaa
     1621 accttctggt gaagtaaatt gtccagtcca tactgattac ttaaattatc gaattaattc
     1681 tataaaaaaa agacatcccc atttggttca tttaactcct cataaacttc gacatactta
     1741 cgcaacttta gctagacaag gtggggctga tatgaatcaa atttctaacg ctttgacaca
     1801 ttcaggtatt tcaactacaa aaatttatgt gaatacacct gatttagttg ataaagctgt
     1861 gttcgaagcg tttcagcgag gattacaaaa atctaattaa tgtgttctag aatgtgttct
     1921 aaatataaaa aaaagacact ttccaaataa ttggaaagcg tcttgaacgt tgatatataa
     1981 aggatattaa cgttttgaga attgagatgc tttacgagct ttcttaagac ctggtttctt
     2041 gcaaaattat attagcctca actgaaagat ttattttttt gctccctaac ttcattagta
     2101 ataccatgtt tcattcgata tcttctaaac gttctacgat taatccctgt tagctcttca
     2161 acttctttat ctgtagatcc agtcaaaaac aaattaaatg ctaattgaag tcgcggatca
     2221 ttctcacgat attttagcgt acctcccttg tatttccctt ttgctttagc gagtgcaatt
     2281 ccttgttgtt gcgtttcgcg aatataccga cgttcttctt cggcctggta cttgtatagt
     2341 tcgataatta agttattaag taatcgacgt aaattatcat cagtgatacc tgttaacgct
     2401 ggcaaattca aaacttccag tgtagctttc ttcagctgaa ttaaattcat cgtttctgtt
     2461 agctctttat tatttcgtcc aagtcgtttt aattctgtca caacgacaat atcaccttca
     2521 cgtatgaatt tcatcatttc ttgaaatcct tctcgattgg tatctttccc acttgcttta
     2581 tcactaaaaa ttttatcaca ctctgataat aattctaatt gtcggtctaa attttgatct
     2641 aagctgctta ctcgagcata cccaattttc gccataataa aactccttta aaattctgaa
     2701 atccggatca tttttaaatt ctgttgccca actctgttgt catttttcta gataaatggc
     2761 ataaattttc agcgctaagt gacaaaagca actaattttt catgatagat ttttaaatat
     2821 ctcaatctat ctccaaaatt agttgctttt gtagctatag ttgactatga atatgacaaa
     2881 taattagaa
//
LOCUS       DACDAF010000156         2857 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.165, whole genome shotgun sequence.
ACCESSION   DACDAF010000156 DACDAF010000000
VERSION     DACDAF010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2857
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.165"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            198..644
                     /locus_tag="IVZ69_002705"
     CDS             198..644
                     /locus_tag="IVZ69_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HAP8184719.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            917..2269
                     /locus_tag="IVZ69_002706"
     CDS             917..2269
                     /locus_tag="IVZ69_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase"
                     /protein_id="HAP8184720.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            2440..2727
                     /locus_tag="IVZ69_002707"
     CDS             2440..2727
                     /locus_tag="IVZ69_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184721.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
BASE COUNT         1013 a          461 c          562 g          821 t
ORIGIN      
        1 cttttaaaga tgaaaagaac acacaaaaat ttatgatgag aaaaattatt tgaatagaga
       61 cgtagaatag tgaacgcgac tgttttacgt cttttttcat taaaatacaa taaaattgaa
      121 ttttcttttc atgttaagtg gattttaaaa tgtaaaaata gtatgataag acgagaataa
      181 caacgtgggg tgtttacatg gaaaataagt tagtcgaaga ggttatcgaa aagttaaaaa
      241 aagagaacat tcgaatcaca cctcaacggt acgcggtttt agaatatttg attgaacatc
      301 attcccatcc aacggctgat gagatttata aagcacttga acatcggttt ccaaatatga
      361 gtgttgcgac tgtttacaat aaccttcgct tatttacttc gattggattt gttcaagaaa
      421 tgaagtacgg cgatgcttct agccgatttg atttcagttc aaagcgtcat tatcatgtaa
      481 tttgtgaaaa ctgcggtaag attgttgatt ttcattaccc agggcttgaa gatatagaaa
      541 tggctgcaag cagactgact gattttgaga ttaatgaaca tcggttggaa ttgtatggac
      601 tctgtccgga ttgtaaagag tcagcaaaaa aggcgcaaat gtaaaaacag tttctacaag
      661 tgttatacct aaaaaaagct agctgtgtaa aaaaaacgct agctttttta tttttttgtc
      721 ttttattcac aatcttagat ataaaagtga atattattaa aataagaatc ttgtagatat
      781 tgggttctta tgcttgaaaa ggaatgaaac tacaaacaaa cctttgtgaa ttcacaagca
      841 ttaaactgtt gtatccgttt tatttctgtt atagtagttt tgtcgaagga caaaatgtta
      901 atcggaggga ccataaatga aagtagtagt aattggctgt actcatgcag gtactgcagc
      961 tgtaaaaagt attttaaaaa atcatccaga agcagaagtg acagtatatg aaagaaatga
     1021 caatatttct ttcttatctt gcggtatcgc actttatgtc ggcggagtag taaaggaccc
     1081 agcaggcttg ttctactcaa atcctgaaga attatcttca ttaggagcaa cagttaaaat
     1141 ggaacacgat gtaacagacg tcgatacaga aaataaaaca gtaacggcaa aagatctgaa
     1201 aacaggagaa acagaaacgg tttcttatga taaattagtg atgacaactg gttcatggcc
     1261 tattatccca ccgattagtg gaatcgatgc gaaaaatgta ctcctatgca aaaactacaa
     1321 tcaagcaaat gaaattattg cacaagcgaa agaagcaaaa cgtgtagtaa ttgttggtgg
     1381 tggatatatc ggtattgaat tagtagaagc ttttgtcgaa tctggaaaac aagtgacatt
     1441 gattgatgga ttagatcgca tcttgaataa atatctagat aaaccattca cagatatctt
     1501 agaaaaagaa ttgacagacc gcggtgttac tcttgcgcta ggcgaaaatg ttactgaatt
     1561 tatcacagat gaagaaggaa aagtgaaaca agtagctaca ccaacagata catttgatac
     1621 agatatggtc attttatgtg tgggcttccg tccaaataca aaactgatcg aaggaaaagt
     1681 agatacactg ccaaacgggg caatcaaagt gaatgaatac atgcagacaa gtaatccaga
     1741 catttttgca gctggagact ctgcagtagt caactacaat ccaagtggca cgcaaaacta
     1801 tattcctttg gcaacaaatg ccgttcgtca aggtttgctt gtgggaaata acttgacaga
     1861 tcataaaatg gcgtatcgtg gtactcaagg aacttcagga ctttacctat ttggctggac
     1921 gatcggttcg acaggtgtga ccaaagaaag cgcaactttg aacgatctag aagtccaagc
     1981 gactgtattt gaagataatt atcgtccaga gttcatgcca actactgaaa aagtaatgat
     2041 ggagctagtc tatgaaaaag gaacgaatcg tatcgtaggt gctcagttca tgtccaaata
     2101 cgacattaca caatcagcaa ataccatgtc tttagctgtt caaaataaaa tgactgtaga
     2161 agatctcgca ctttcagatt tcttcttcca accacatttt gaccgcccat ggaattactt
     2221 gaacctactt gcacaagcag cgctaggcga aatcgaaact gcacaataaa gaaaaagggt
     2281 tgtgacacaa ttttgtcacg accctctgtc tttttttgtg aaaagtacaa ttagttgtct
     2341 ttcttcgaat tttttgtcac aataagcagc aaagataaag ctgttacata aaagaacaag
     2401 cagctttatt tgattttgaa aagaaaggtg agaaagaaga tgaataaaga atattttgtc
     2461 caacaagatg catttttaga agattataaa agtgcttcga agaaattaac gatcaatatt
     2521 gatgagttgg cagatcaagt actctctcag ttgaatgaaa cgcaagagga atattacacg
     2581 atgccagcaa atgacgccaa agataatgtt tctcatcgtt ttcctttcag tagacgcatc
     2641 tactcagatg aaaatgacgg cacattgaat acagagtaca catatgaagg tcagccatat
     2701 gtgctagaaa ctgatgatga tctttaaaga cagtttttga aaaggccgct catccttaag
     2761 tgatgacaaa aaatcatcac aattaccgat gactgtctct ttactatctt ttaatcagaa
     2821 aaaggggtta tgacaagctt tgtcaacccc ttttttt
//
LOCUS       DACDAF010000157         2731 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.166, whole genome shotgun sequence.
ACCESSION   DACDAF010000157 DACDAF010000000
VERSION     DACDAF010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2731
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.166"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(40..1416)
                     /locus_tag="IVZ69_002708"
     CDS             complement(40..1416)
                     /locus_tag="IVZ69_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010767236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HAP8184722.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(1544..2662)
                     /locus_tag="IVZ69_002709"
     CDS             complement(1544..2662)
                     /locus_tag="IVZ69_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HAP8184723.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
BASE COUNT          854 a          557 c          437 g          883 t
ORIGIN      
        1 tttattcaag caacacgtct ttcataacca agtttccaat tatcttcttg gctcgtcatc
       61 ttcgaattct tttctgaagt atcttcgttc ttcttcaggt tccgcttctg tttcttccgg
      121 atcatgaaaa atgacacgga ttttaaggat tcgagaacct tccatttctt cagaaaccag
      181 cgtaatatta tcgacatcaa acgataactt ttcgccttca tccggaatca tgcctaatgc
      241 tgtaatcaaa taaccagcca tcgtatctac atcactcata tgcagatcac tgtcaaaagc
      301 ttcattgaac tcatcaatca gcatacgtcc ttggatgata tattcgtgtt catcgatttt
      361 ttcataaaga ttctcaactt catctgattc atcatcgatt tctccgacga tttcttctaa
      421 aaggtcttct agtgttgcta acccaacgac gccgccatat tcatctaata aaatagccat
      481 ctgattctgc gtctttttca tttcatataa cagatcatca ataaagaccg tttcaggaac
      541 gaataaaggc tcctgcatga ttttcttgat atctaaatta tcaaagccga atttatgggc
      601 agcttttagt aaattctttg tatgaaggat tccgactact ttatctttgt cttcgttata
      661 aacagggatt cttgaatagt tttcggataa aacttcattc acattttctt ccacagtgtc
      721 gttgatatca atcataaatg catccgttcg tgggaccatg acttctcggg caactttcgt
      781 atcaagagaa aaaacccctt ggagcatttc taattcttca ttattcaata cgccttcgtt
      841 ttcaagcata taacgcattt catctctggt catttttgaa tcttcatcat caaaagtcat
      901 cggcgtgata cgcgccaata aacttgtgga agcagaaagc agccagacga agggcttagc
      961 tactacacca atcaagcgta tcagccctga agtgaacttt gcgacttctt ctgatttatt
     1021 taaagcaata cgtttagggt acaattctcc aaaaacaatc gatacatagg tcaaaatagc
     1081 cagcacaatg atatttgcaa tattttttgc cgctgtgccg ccacctaata ccggagctaa
     1141 ccgttccgat aaagtattag ctagtgaagc accagacaaa atgttgacca aagtgattcc
     1201 tacttggatt gtcgatagga aattatttgg attctgcaat atttttaaaa gcttttgaga
     1261 tttcacatct ccttcatcag ctttttgctc gattcgattc ttattgatcg aaacaacagc
     1321 aatttcggaa gctgctaaaa aagcattgat caatgtcaaa acgatcaata ataaaatctg
     1381 cgctaacagc gactgactct cagggtcagc attcataatc gcattctctc cttataaaat
     1441 taatttttag tttacgatag aaaaaaacgt ggcactatag ccacgttaaa atggtatcac
     1501 aaagcaattt tctttgcaat aaaaacaagt gtactaaaac tacctacgag gtcgtagcaa
     1561 ttttcttctt gttttcattt tgcttgtctt ctttgacgat tttgattata taggaaatga
     1621 tcgtcttgca gattgcgtaa aaaggaacac ctaagaagat accaagcaat ccggcaatat
     1681 ttccagctac tagaagaacg ataatgatcg ttaatggatg gattttcagt gatttcccaa
     1741 ttacattagg ataaatgata ttcccatcca actgttggac gattagcaca accacacaac
     1801 aaagtaatgc ttttaccgga tcattgaaga ctgttactag aaatgcaggt gctagtccta
     1861 gataaggtcc taaatatgga attaggtttg tcaatcccgc aatgacccca aataagaaag
     1921 cataatccac accaattacc atatatccta aaaatgtgaa ggtaccaacg aataaacatt
     1981 cgattgcttg tccgctaatg taattagcca atgttttatt cagttgcccc aataactcca
     2041 caatttggtt tcttcttttt tctgggaaaa actgttggat gtttggcact agtttttctc
     2101 cgtctttcaa catatagaac aagatgaatg gtgctgtaat gattactacg gttgccgaag
     2161 cgatcgttcc aacgatcgaa cctaaactat tggatactcc actaaggaat tgctgaatga
     2221 ttgtcccgta agaaatgtct aattgctcaa aatatttatt gatatctact tccttgaaca
     2281 aaggcaattc ggctacctct tttaaccagc tttctacctg tttgatgaaa tcaggcatat
     2341 tagatgccaa tgaggaaatt tgctgtacta gacttgggat gacactaagt aaaatccaaa
     2401 taattgctgc aactaaaagg agcagcacaa ttgcgacagc ccatattctt ttgatttttg
     2461 ctttcatcaa cagcttgaca ataggattca ataaatagta aagaaagcct gcaatcagta
     2521 caggtgcaaa taacgtggaa aaaaatgtcc cgatcggttc gaaaataaag tttatttctg
     2581 atgaaatcat gatcaatgca gctatgatca ataattcaag cgaccaaaac attagtttag
     2641 actgtctaag tttttcaaac aatagatttc ctcctttctt tcttactagt atatattata
     2701 ttcgttaaaa attcttttat tcttttttta t
//
LOCUS       DACDAF010000158         2659 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.167, whole genome shotgun sequence.
ACCESSION   DACDAF010000158 DACDAF010000000
VERSION     DACDAF010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2659
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.167"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..235
                     /locus_tag="IVZ69_002710"
     CDS             <1..235
                     /locus_tag="IVZ69_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184724.1"
                     /translation="NIGPKVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKG
                     RYVTSTPFDEDLSFVNKKKCSYAYVKAIKAVVR"
     gene            232..543
                     /locus_tag="IVZ69_002711"
     CDS             232..543
                     /locus_tag="IVZ69_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184725.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            533..886
                     /locus_tag="IVZ69_002712"
     CDS             533..886
                     /locus_tag="IVZ69_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HAP8184726.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            876..1277
                     /locus_tag="IVZ69_002713"
     CDS             876..1277
                     /locus_tag="IVZ69_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184727.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            1270..1674
                     /locus_tag="IVZ69_002714"
     CDS             1270..1674
                     /locus_tag="IVZ69_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184728.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            1686..2294
                     /locus_tag="IVZ69_002715"
     CDS             1686..2294
                     /locus_tag="IVZ69_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP8184729.1"
                     /translation="MAKTKTVVTTFDNVSIKRIAFNFKNAGNAIATNCNGQLDGETEM
                     QTVVKKCGATEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDGRIKPGIYSYGPDSV
                     GEDFSLAAEIVDDFEENRKLVGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFG
                     KFYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            2314..>2659
                     /locus_tag="IVZ69_002716"
     CDS             2314..>2659
                     /locus_tag="IVZ69_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184730.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKE"
BASE COUNT          986 a          389 c          529 g          755 t
ORIGIN      
        1 caatattggt cctaaagttc acgaggaatt agacttttgt tttgctactg atccaataga
       61 aaaagttaaa gaagtaaaaa tcttacacaa tgctggagta acaacaaacg atgaagattt
      121 atttttcaaa gggagatacg tgacttctac gccttttgat gaagatttat catttgtaaa
      181 caagaaaaaa tgctcttacg catatgttaa agcaattaag gcggtggtta gatgacgcct
      241 gaacaagtga ctgaagaatt gctaatagct gtgaaggata atatttacgt tacctggaac
      301 gaagaagatg agtcaattaa aaagatgata gctaaaaatg ctgtttatct tcaaagtaaa
      361 gtgagtacaa cactttcttt ttctcctgaa agcttagaat acggattgct aatcgaaaga
      421 tgtagatacg actggaatcg tgctttagat gagtttgaac aaaatttcgc tagtgagtta
      481 ttaggtttca ttcaacatta tgcgctacaa gaatatattg caggtgatgt gaatggcgaa
      541 taatcgtaga ctcgaagaaa cattcaacga tggttggtta aagattttga cgcaaactac
      601 caaaagaaat gaactaggaa aaaagattgg tgtagaagat acagaaatca cttctttaaa
      661 atttagaaat ctttccatga gagatagtga tataacagct atggatgcga tgggatcgaa
      721 attaactaag aaagtaaaga ctccatttca tccaatcgcc aagaaattta ataaagatca
      781 atattttatc gtaatcgata gtatgcgtta caacgttatc tatgccgatt acgataattt
      841 ttatatctat ttttatcttg aaagtgtggg tgaatatggt gattgataat tctaaagaaa
      901 aagaacgttt aaataagcaa atttctgcta tcaaaacttc cttagaagag cattttggcc
      961 tcaaactctt tcaagactcc gtaggcgagg atgagctacc tgatgatttt aattacttca
     1021 ttctcgaaac aggagaaata gaaatgatca ctgagccaaa atatagcgtg ggtcaaaatc
     1081 tatatctaac tttctattca gaaaatagag aagatttaac aggagactca ctagatatta
     1141 tttcattgat tcaaaatcgt tcgattcgtt ttcagagaat ggatcccaat catttaaaac
     1201 tagagaacca agatcgctat atcgatcaat tggtatttac gtttagacga ttattgaaga
     1261 gtgattgtca tggctaaaaa tagttgggag ctaaaaataa atggacatga tgaacttctt
     1321 gtgcggatgg aacgctattc aagcgagagc gaacgactga ttaacgaagc attgaaatca
     1381 aaaggttcgg ctattgcagt ggataggatt acagaaaaaa ttcctgtttc tgaagcagat
     1441 ttaagaagag ggcaccaaca cgcaaaaaat agtcgtccac ttaagactca atacattaat
     1501 ttgggtttca tcattagacc tacaagaaaa tttgagtatt taaaatatcc tgatttgggg
     1561 ataggtactt ctaaaagaaa tcagccggac gaatttatga gaagaggatt aggtcttgca
     1621 cttgatccaa ttacagaact tctgattcgt caattcgata aattaaataa atagggggaa
     1681 caacaatggc taaaacaaaa actgtagtaa caacgttcga taacgtaagt atcaaacgaa
     1741 ttgcttttaa ttttaagaac gcaggaaatg caatcgcaac gaattgtaat ggacaattag
     1801 atggcgaaac agaaatgcaa acggtggtta aaaaatgtgg agcgacagaa gtaaaatcaa
     1861 aatctaaacc aatcaatatg acggtaacaa ttactgcaca tgtaccgatg gaagtttatc
     1921 gacgtttcaa tgggttgaaa caagatggac gtattaaacc aggcatttac tcttacggtc
     1981 ctgattccgt aggcgaagat ttctcacttg ctgcagagat cgtggatgac ttcgaagaaa
     2041 atagaaagtt agttggtatg ttagcatgca cttcgaatac aggattaaca ttctctattg
     2101 aaaatggtgc ggatgaagta gctgcgttag aactagaaac aaaagttatg caagatgaat
     2161 ttggtaaatt ttatcatgaa gcaattgttg cagaacttga agaagactta acagatcaat
     2221 ggatgacgaa tctatctgct gatgtgatta aaaaaacttc agttgtgaca actacggcca
     2281 ctcaatcaca gtaaaaaaaa cggaggtagc gaaatgaacg aagattactc aaaaattgaa
     2341 ctaaacgatg gaacaatttt gaatttagaa cctaaactga atatcaagaa attattgatg
     2401 atcaatagag attttaacac agacgagttt gcaaaaatga ctgtgggaaa aggatccatg
     2461 gatatttctg ttattcaagg tgcaaaggct gtgtatattg cttaccgcca agcgaacatg
     2521 actgattata tttcattcga tgaatttatc gataaatggg attttgatat ggctactgcc
     2581 agctatattt atcaattgat gatgttcaaa caagcacgcg atgcttatca aaaagaattt
     2641 gaaaaagcaa ataaggaaa
//
LOCUS       DACDAF010000159         2527 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.168, whole genome shotgun sequence.
ACCESSION   DACDAF010000159 DACDAF010000000
VERSION     DACDAF010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.168"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            15..266
                     /locus_tag="IVZ69_002717"
     CDS             15..266
                     /locus_tag="IVZ69_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HAP8184731.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            368..2365
                     /gene="tkt"
                     /locus_tag="IVZ69_002718"
     CDS             368..2365
                     /gene="tkt"
                     /locus_tag="IVZ69_002718"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HAP8184732.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
BASE COUNT          841 a          466 c          573 g          647 t
ORIGIN      
        1 aaggagggct gagcatgctg tcacctgaaa aaatagagcg gatcaatgaa cttgcacgta
       61 aaaagaagga aaatggtctc tcaaaagccg aagaacaaga acaaatcaac ttgcgcaaag
      121 agtatttgga agcttttcgt tccggtatgc gtcatcatat cgaaggaatg aaagtcgtcg
      181 atcctgaggg caatgacgtg accccggaaa aattaaaaga aatccaaaag aaaaaaggct
      241 tacacaaccg aaatgacaac ttttagtaaa aaatactgaa aaagattgct ttttcgtgtg
      301 acatcttata gaatgaaagt gtaagaaata aaggtaaaaa aaacctaaat taataggagg
      361 ggttattttg tttgacaaaa ttgaccaact tggcgttaac acaattcgta cattaagtat
      421 tgaagcagtc caaaaagcaa actcaggaca tcctggattg ccgatgggcg cagcacctat
      481 ggcatatgcg ttatggacaa aacacctgaa agtaaatcca acgacatcaa aaaactgggc
      541 tgaccgcgac cgtttcgttc tttcggcagg acatgggtca gcaatgttgt atagcttgct
      601 tcatttagct ggctatcaag tgacaatcga tgatttgaaa caattccgtc aatgggattc
      661 taaaacacca ggacatcctg aagtacatca tacagatggt gtagaagcca ctacagggcc
      721 attaggacaa gggattgcaa tggctgtcgg tatggcaatg gcagaagcgc accttgcagc
      781 aacgtataac aaagaaaact ttaatgtgat ggatcactat acgtatgcaa tatgcggtga
      841 cggagacttg atggaagggg tatctcaaga agcaagttcg atggcaggtc atatgaaact
      901 agggaaattg atcgttttat acgattcaaa cgatatttca ctagacggtc caacttcaaa
      961 agctttcaca gaaaacgttg gtgctcgcta tgaagcatat ggctggcaac atatcttagt
     1021 gaaagacgga aatgacctag aagcaatctc taaagcgatt gaagaagcaa aagctgaaac
     1081 agacaaacca acattgatcg aagtaaaaac agtcatcggc tatggtgctc ctaaagaagg
     1141 aacatctgct gttcatggtg ctcctcttgg tgaagatggc atcaagatgg ctaaagaagt
     1201 ttatggttgg gagtatccag atttcactgt tccagaagaa gtagctgccc gcttccatca
     1261 aacgatgata gaagaaggac aaaaagctga agatgcatgg aatgaaatgt ttgccaatta
     1321 taaaaaagct tatcctgaat tagcacaaca atttgaagat gcttttgatg gcaaactacc
     1381 agaaaactgg gatgcagaat tgccaactta tgaagttgga agcagtcaag caagccgtgt
     1441 ttcaagtaaa gaagtcatcc aagaattatc gaaagctata ccaagcttct ggggtggttc
     1501 agcggacttg tcaggttcca ataatacaat ggtggctgca gataaagatt tcactcctga
     1561 acattatgaa ggacgcaaca tctggttcgg tgtccgcgaa tttgcaatgg cttcggctat
     1621 gaatggtatc caacttcatg gcggaactcg tatctacggt ggaacattct ttgtctttgt
     1681 cgattatcta agaccagcag ttcgtttagc agcaatccaa catactcctg ttgtttacgt
     1741 cttaacacat gactcggttg ctgtcggaga agacggacca acgcacgaac cgattgaaca
     1801 actagcatct gttcgctgca tgcctggtgt tcaagtgatt cgtccggcag acggaaatga
     1861 aacacgtgct gcttggaaag tagcgatgga gacaacagat gcgcctacta tccttgtatt
     1921 gagtcgtcaa aaccttccag tattgccttc tacaaaagaa gtagcagatg aaatggtgaa
     1981 aaaaggcgcg tatgttcttt ctccatcaca aggagaaaca ccagaaggta ttttgattgc
     2041 aacaggttct gaagttgatt tggctgtgaa agctcaaaaa gaattggctg aaaaaggcaa
     2101 agatgtttct gttgtttcta tgccaagctt tgacctcttt gaaaaacaat cttctgaata
     2161 taaagaaagt gtacttccta aatcagtgaa gaaacgtgtg gctatcgaag ctgctgcatc
     2221 atttggatgg gaacgctacg taggaacaga gggcgcaacg attacaatcg atcatttcgg
     2281 tgcatctgcc cctggcacta aaattttaga agaatttgga tttacagtag aaaatgtcgt
     2341 gaatacgtac aatcaactat catagatcca agcaattgtt tgactgataa gaacagctgt
     2401 ctgcaagttg gagacagctg ttctttatgt gttagaagaa taaatcaata ttacttttcg
     2461 ttttcggcta tgttacattt aaatgacaaa acaaagaatt cttcggatta gtttgtgttt
     2521 cttgaga
//
LOCUS       DACDAF010000160         2459 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.169, whole genome shotgun sequence.
ACCESSION   DACDAF010000160 DACDAF010000000
VERSION     DACDAF010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.169"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..585)
                     /locus_tag="IVZ69_002719"
     CDS             complement(<1..585)
                     /locus_tag="IVZ69_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184733.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDNVATSVTSEEVTFSLDGTFMSEAGYYKHCYVEYRKDNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSI"
     gene            complement(609..>2459)
                     /locus_tag="IVZ69_002720"
     CDS             complement(609..>2459)
                     /locus_tag="IVZ69_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184734.1"
                     /translation="VDTLANVKIEKANFLEFFGGKEGSILDRFHGEFLKDNNTLRHEK
                     RLGTDHKIKAIYTKNLTGLDLEIDAQSVLVGVYPFISSSSEGEDEITLPEEVIFTDYV
                     DDYPAGYVSFVDFKDKATDVATLREAAKDWLKTNIDKQKPQVSGSIELVPLRHQRGYE
                     KFVDLEKVSMGDGVDVYHPQLKVNMSARIVEYTFNVLTNSYDKLVVGNVKTNFLENTE
                     NNVSNLINDAIDQLKNGGEISDLLNDIVDHQTDMITGQNGGYVLLDPKEAPSRILIMD
                     TPDKNTARNVLQINNAGIGFSKTGINGTYETAWTLDGGFNASFITAGEIVGITIRGTT
                     LISDGADYRTSIANGKMTWYSKKVNKDIMELEARDYVSADAGIVSYTMKTGGGFMIRN
                     PQGNLVFSTWDNGNNRPFLSFGAPNFRYSNASYVTSGDGSSLSINGSAGNSWEFKVAG
                     RTMKFTSDGMLTLPGCFFGSWEDGKLARFEQSTVQVYKDFTVRGTKNSTVPTEHYGQR
                     LLNAYETPEYYFADYGEAVTGDDGKVRVDIDPMFAETVNLSRYMTHVTPTELVLCAVT
                     HEDIDHFIIETSKPNVLVRWNLVAHRLGYEDIRLKEDTAYDSTVLDQKRF"
BASE COUNT          728 a          535 c          356 g          840 t
ORIGIN      
        1 gatgctgtta ctgtacatca cttgtaagtt acctaactta gaaatttctt ctttcagagc
       61 atctaacttg tcttgtagcg ttttagcttg accagttaaa tcagtaatct gttgatttaa
      121 gctatccact ctacctttga tttcagccat aaaagcatca aaagtttcgt tgtactttcg
      181 aatcaactct tctaattgcg aaacatattc atcggcttgg ccttgcgaaa tgtcagacac
      241 tcctagtgag aaaaaaatga tatcttgcgt tgttaaaatt tgattgtctt ttctatattc
      301 tacgtagcag tgtttataat atcctgcttc actcataaat gtgccatcaa gagaaaacgt
      361 gacttcttca ctagttacac tagttgcaac attatctacg taacggttag atggtgttgt
      421 tccttttaaa gtaaatgttc cgccactcgt atccatctgc aagccattta gaaacggttt
      481 aaccgtcacc gtaatccctt tatcaccttg acgagccata atagctttgg tgtagtttaa
      541 ttctttgctg aaatctaaag ccaaattata taaactgcta gccatttata tacctccttg
      601 tcttcgtttt aaaaacgttt ttggtcaagc actgtgctat catatgctgt atcctctttt
      661 aatctaatat cttcataccc tagacggtgt gccactaaat tccatctaac taatacgttt
      721 ggcttactag tttcaatgat gaaatggtca atatcttcat gagtaacagc acacaaaact
      781 agttctgtag gtgtcacatg tgtcatatac cgacttagat ttactgtttc agcaaacatg
      841 gggtcaatat caacacgaac tttaccatcg tcacctgtaa cggcttcccc ataatcagcg
      901 aaataatatt ctggagtttc ataagcgttc aatagtcgtt gtccataatg ttctgttggt
      961 acagttgagt ttttagtacc tctaacagta aaatctttat atacttgtac cgttgattgt
     1021 tcaaacctag caagtttccc atcttcccat gaaccaaaaa aacaacctgg taacgttagc
     1081 ataccatcac tagtaaattt catagtccta ccagctacct taaattccca tgagttaccc
     1141 gcactaccat taatgcttaa agaactaccg tcgccagaag ttacataact agcattgcta
     1201 tacctgaaat tgggcgcacc aaaagataga aacggtctgt tattaccatt atcccacgta
     1261 ctaaaaacca agttaccctg tggatttcta atcatgaaac caccaccagt tttcatggtg
     1321 tatgatacaa taccggcatc agcacttaca taatcacgtg cttctagctc cataatatct
     1381 ttgttaactt tttttgagta ccaagtcatt ttgccattag caatacttgt tctataatca
     1441 gcaccatcac taattaatgt agtacctcta atagtaattc ctactatttc accagccgta
     1501 ataaacgagg cattgaatcc gccatctaac gtccatgccg tttcatatgt tccattaatg
     1561 ccagttttag aaaaaccaat accagcattg ttgatttgta aaacattcct tgcggtattc
     1621 ttatctggtg tgtccataat caaaatacga ctaggcgctt ctttaggatc taataaaaca
     1681 taaccaccat tttgaccagt aatcatatca gtttgatgat ctacaatatc attgagtaaa
     1741 tcactgattt cgccaccgtt tttcaattga tcaatggcat cattaatcaa attgctgaca
     1801 ttattctctg tgttttctaa gaagtttgtt ttgacgtttc ctacaactaa tttatcgtat
     1861 gaattggtta gaacattaaa cgtatattcc acaattctcg ctgacatatt cacttttaac
     1921 tgtggatgat acacatctac tccgtcaccc atcgaaactt tttctagatc aacaaatttt
     1981 tcatagcctc tttgatgcct caatggtact aattcaatcg aaccactcac ttgtggtttt
     2041 tgtttatcta tgtttgtttt caaccagtct ttagcagctt cccttaatgt ggctacatca
     2101 gtcgctttgt ctttaaaatc aacaaaagaa acatatccag caggataatc atccacgtaa
     2161 tccgtgaaaa taacttcttc tggtagagtg atctcgtctt ctccttctga agagctgcta
     2221 atgaatggat aaactccaac taaaacactt tgagcatcaa tctctaagtc aagaccagtt
     2281 aagtttttag tataaatcgc tttgatttta tgatccgtgc ctagcctttt ttcatgacgt
     2341 aatgtgttat tatcttttag aaattcccca tgaaatcgat ctagaataga tccctctttt
     2401 ccaccaaaga attctaaaaa attcgccttt tctatcttca cattagcaag cgtatctac
//
LOCUS       DACDAF010000161         2431 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.170, whole genome shotgun sequence.
ACCESSION   DACDAF010000161 DACDAF010000000
VERSION     DACDAF010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2431
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.170"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            131..2284
                     /locus_tag="IVZ69_002721"
     CDS             131..2284
                     /locus_tag="IVZ69_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HAP8184735.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT          831 a          427 c          538 g          635 t
ORIGIN      
        1 ctgtgaaaca aaaagttgat tttatcttga aattaggtaa agaatttctt gctccgccca
       61 ttttttcttt tttattaaga agtttttggg tacaatgaag catgaatgta aataggcgga
      121 aggataggaa atgatgaaag attttatgaa aaaaatatta aatacttctt ggttagaaaa
      181 aataagaaaa ggtgcacaag aacctaagaa caaaacgttt cgccggtccc atgttccttt
      241 tcgcttaaat tttctttttt tcattatatt tacgttattt gttgcgttga ttgctagatt
      301 gggttatttg cagatcgtga acggcgaaga gatggaggcg cgagtgaagt ctacttctac
      361 gattacggtc caagaaagta ctcctcgcgg aatgatctac gactccacag gaaaagcttt
      421 agttacgaat aaagcgaatc aggccatcac atatacgaga ggaacacaag ttacggctaa
      481 agatttgctt gaaatcgcaa cgaagctgaa ctcgctgatc gatgttccgg tagatgaaaa
      541 tctgacagat agagataaaa aagatttttg gctggctgat cccaaacatt tgaaagaagc
      601 cacaaaaaga ctttcggcaa aagaaaagca attagggaac agcgaacaat atagtgcgat
      661 ggtcaataaa gtcacagctg atgagattaa tttaaacgag gagcaattaa aaattgctac
      721 catctttaaa cggatgaata gtgcatatga attaaacact gtctatatca aaaactctgg
      781 tgttactgat caagagttag ctgttgtggc agaacgcgct tctgaacttc caggagtttc
      841 gactggcaca gactggacac gagaatataa tgcagcaagt tcactgaaaa gtattcttgg
      901 cagtgtgacg actgaaaagc aaggacttcc agcagatgaa gcagagaaat acctagcaaa
      961 aggttattct cggaatgacc gtgtaggaca aagttatttg gaaaaacaat atgaagatgt
     1021 cctgcaagga accaaaaccc aatatgaagt ttcccttgat aatgaaggaa atgtttcgaa
     1081 tcaaaaagaa atcttctctg gggaaaaagg ttctaattta atgttatcta tgaatgcaga
     1141 attccaatca aaagtagaag aaattttgaa aaggaattat caaacattga tcaacaacgg
     1201 caaagcacag tattcgcctg gtgcttatgc agtggctatg aatcctcaga caggagaagt
     1261 gctagcaatg actggtttca gtcatgaaca aggttccaaa gaaatcaccg agaatgcttt
     1321 aggcacgatt actagcgcct ttgatccagg gtctgtagtc aaggctggta ctttgacagc
     1381 aggctgggca agtaacgcga tcagcggaaa tcaagttttg attgatgagc cgattcgtct
     1441 gcaaggtgct tcagaaaaaa gctctgtctt taatcgaagc ggacaagttg ctcttgatgc
     1501 agtcaaagca tcggaattgt cttctaatac gtatatgatc aaagtggcgt taaagatgtt
     1561 aggactagac tatacacctg gaatgggact acctagttta gatgaagaag ctaaagctta
     1621 tcagcaattg agagactctt tcaaagagtt tggtcttggt acaacgactg ggatcgattt
     1681 gccgaatgaa tctcctggga tctcacgttc tgttgattat atgaagaagt tcaatgcgga
     1741 taatggcaaa gaatggtatg ctccaggtaa ctttaccgat ttggcatttg gacagtttga
     1801 cacatataca ccaatccaat tagctcaata tgcttcaaca gtcgctaatg gcgggaaacg
     1861 agtacagccg cacctagtca aagcgatcta tggcaatgac gaaaatggaa acttgggtga
     1921 agtgaagaaa gaaattggca caacagtaga aaatacggtc aatatttctg cagaaaatat
     1981 ggcgatcctc cgtgaaggat tccaccaagt tgtccatggt accgatcctt acacaacagc
     2041 caaaccatta gccagtgcga aaatggacct ttccgcaaaa acagggactg cagaaacggt
     2101 tgcggaaggt catccagata ttgcgacagt caatagtaat atcgtggcat acggaccaac
     2161 agacaatccg gaaattgcca tcagtgttgt cttgccgaac ttattagacg aacaagacca
     2221 cataaacttg acgattgcta aagaaataat ggacgcgtat tatgatatgt tcatggcaaa
     2281 ataaaaaaga ggtcgtgaaa aagccgctta gtttcgagta tgaagaaaaa ttttgtgaaa
     2341 atagcttctc acatttttgc ttaaatttga cttcataccg agaaactggc ttttgaacac
     2401 cgtttactcg gcaaaaaagg ttgtgacaaa a
//
LOCUS       DACDAF010000162         2424 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.171, whole genome shotgun sequence.
ACCESSION   DACDAF010000162 DACDAF010000000
VERSION     DACDAF010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.171"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            287..694
                     /locus_tag="IVZ69_002722"
     CDS             287..694
                     /locus_tag="IVZ69_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184736.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
     gene            708..1109
                     /locus_tag="IVZ69_002723"
     CDS             708..1109
                     /locus_tag="IVZ69_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184737.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            1111..1482
                     /locus_tag="IVZ69_002724"
     CDS             1111..1482
                     /locus_tag="IVZ69_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184738.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(1518..1818)
                     /locus_tag="IVZ69_002725"
                     /pseudo
     CDS             complement(1518..1818)
                     /locus_tag="IVZ69_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339959.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1833..2054)
                     /locus_tag="IVZ69_002726"
     CDS             complement(1833..2054)
                     /locus_tag="IVZ69_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184739.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKN"
BASE COUNT          874 a          335 c          404 g          811 t
ORIGIN      
        1 tgaggggaag tacatatagt tgttgatata gttgctaata ttgttagcta atttgttagt
       61 aaaactgtat acgaatttag atagtaaaaa aacagtttgt tccttatata gaggcacttt
      121 tactactgat taaatgtcag atatgcttac aaatatactt ataaatatgc ttacaaaatt
      181 agctaatatt tccgttgaca aagctttgtt actattgtta aactaaattg actagcaaaa
      241 gtgaaacata aatttattaa ataaatgtaa aaattaggag aaatcaatgt cttatagagt
      301 acaattaata atttcagaag atgtagaaag tcagcaattt ggcactaatg ttattaataa
      361 agtaattaat ccagctcttt ctattaatgc gcctttaatt cctactgctt tatcattttc
      421 tgtaacagct gtggtgtctg agatagagga tacagaaaag ataaaaatag tagaaattga
      481 agttttaaac aagaatgaaa aacaaatttt ttctacgggt gaagtatcgg taagcttgcc
      541 tcctcaagtt aacgatataa actttaatat aaacgccaga aatgtcttgg ttgaagaagc
      601 aggagagcat tatgctgttg ttaaatttaa tggaactgag attggaaggc aaatctttga
      661 tatcaaggtc aacaaaccag tggaaaaaaa ttaaggagac gatacggatg cttgatatag
      721 taccatcaaa tacacatcgg agtggtagct taataaattt tgctgcgatt tttgcttgcg
      781 catcggtaat tctagcatct ccagttgttg tggatgcaag ttctactccg aaaactaaaa
      841 atgataatca acttgtaatt actacaaaaa atgagattaa cacaatttca agtaatgatg
      901 gcaaaatttt tgatgtgata aatacggttt taaaaagaaa agctgaaatc aatataaaat
      961 atgatgaaga tttaaacttg tatttctttg ttatcaaaac aacatctgaa ttgttttcct
     1021 cagattacga tgttttggat actctcgata atgtattatc tgactataaa tatatgggga
     1081 aatctgtagt agcaactttg ggggaataaa atgtttgact ttaatgaata tttatctatt
     1141 tccaaacaaa ttgaatcaga tgataaatat aattctaaag aatcttatag aagaactgct
     1201 gtttcaagag catactacag tgcttttaaa aaatctgatg agtatttgaa agaaaattat
     1261 gatattattt ataatggaag tagcggaaaa ggaagccacc aaaccgtttg gaatttgttt
     1321 tcaacagtta aggaattgaa taccttagga atacataata gtgggtatag aatgttagag
     1381 aaaagaaaat gtgctgacta tattcctaat gaaaccatta cgaaaacaga tatggcgctg
     1441 atgaatcgag aagcagaaaa aataataaac aaactcacct aatgaatttc aagcgagttt
     1501 gtttgttatt tttttattta atctttgtat ctttctggat caacgaaagt atactttata
     1561 tagtcataac gccgatgatc gctacgtgcg tccggcacgt cagtcacgat atcaaacaaa
     1621 aagtatacac ccttcttcat tctagttttc gcagcaggaa ttttgaaata gttccttatt
     1681 agaatagtag agattgatta ataagctatc ttcgattgct aaaaagaaaa cttctgaatt
     1741 ccatacttta taaaaatctt tgataaatct atttgaagga tcgaatttaa accataattg
     1801 tgtctcatta aaaagcataa ccattactcc aatcagtttt taaacttagt ttctacctct
     1861 aatatatatc gagtttttat tttgccttca gagaataccg tttctttttt tgcagttaca
     1921 ggttgtttat tttcggaaaa agctaatata gctaaaattg aaacatccat ctggaattta
     1981 tctttttcgt tgctttgttc ataaaaatct gcatattcat cactgatatt ttttctaata
     2041 aattcttcca tcataaaaat cacctcaaaa cgattatacg aacttatgtt ctgactgtaa
     2101 agcgatattt gaggggcaaa aaaggggcaa aaaactctta ctagtccgtt ctagcctaat
     2161 aattttaagt attatcaacg ttgttttttc ttgatataat gggatttttg tccagtacgt
     2221 acaagctaaa aacgtttgtc ttgatgggcg gtatgatgta agaaaaagca acttgcttat
     2281 ctacaactga tcattagtga aagacagata aaaagaggct ggaacagaag cgtttaactc
     2341 caagaaataa gaagaaattc acggaaattg cttttcaaat ttttgtgaat ttcagcttat
     2401 ttccgaagga gttgcttctg cttc
//
LOCUS       DACDAF010000163         2271 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.172, whole genome shotgun sequence.
ACCESSION   DACDAF010000163 DACDAF010000000
VERSION     DACDAF010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.172"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            192..446
                     /locus_tag="IVZ69_002727"
     CDS             192..446
                     /locus_tag="IVZ69_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP8184740.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            447..764
                     /locus_tag="IVZ69_002728"
     CDS             447..764
                     /locus_tag="IVZ69_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HAP8184741.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            1323..2258
                     /locus_tag="IVZ69_002729"
     CDS             1323..2258
                     /locus_tag="IVZ69_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184742.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTFRTNNYKNLNDLSRSISEYL
                     KGNSYLKIRFSHILILLPYLNENFTLIQVDKSFIASGNQGNMNITSNKTSRVLLALMG
                     YGILYRDDQNGQILINRAGRSLLMKYRKFIPEDFQNLQLENMRLEDLFRLAEDDKYRF
                     EVLKIQKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNRNSTD
                     VVMITDIYVEDEDIIKYMKPVIKLVNKNKGTRGAS"
BASE COUNT          823 a          307 c          430 g          711 t
ORIGIN      
        1 ggatgttaac ggaagtgtat ggtgagtagt tcactcgtat tttgatatcg tttgtatatg
       61 ttttcagcgt tctaagtggc ttattttgtc caataataat atggagtgga atcccttaag
      121 aaacaccgtt ggcaattgtt gttataacat gttataattt attcatcaaa aactaaaagg
      181 agtgtgataa catgggaaaa gaactaaagg ttagaaagat cggcaatagc gtgggagtga
      241 tccttccaag ctctcttgga ttaaaaagcg gagacattat ccaagccaaa caagaaggca
      301 acttattcat attagatact actcaaatag caaaagaaca cgatcgcaaa ttgattgaag
      361 aaagtttcca agactttgag aaaggtttaa cagtttcaga aattgaaatg gtaaaagctt
      421 tcggaaaata cggctggagt gaatagatga aagagtacac gctagtttat tctaaaagtt
      481 ttcagaccag ccttgaaacg ataatagaag aatgggaaaa tgagcttgct ctttctccag
      541 ccagcataaa aagatttgta ggtgcgatcc agaaggcttt agaactaacc aaaaattttc
      601 caactatgca tgaggaagtt tccgaaatct atggaatgga tatcccaaca tatcggatcg
      661 tgatcggcaa aagctatgcc ttattttatc ggatcgacca tgaaaaaaaa gagatacttg
      721 taggacgtat tttccaatct aaacaaatga aactaggctt ttaacaataa ttaggaaaaa
      781 gtcgctcatc ctctacaggt gggtgattaa tgccgctcga tatggttgtt aaccgtcggt
      841 tactcgaaga ttgatatata agacttagta cctttttatt ttgctccatg ttatggccga
      901 aggtctaaag atacaatcat tagtctagag aaaaattaag aaccgtagga actacgggga
      961 tcgcttggtg aataagagac actgctatta gtgaaaaaat aagatatcaa gtacgctcta
     1021 ttcccaaaaa tttcgtgact ttactcatga gaggttcaag tagtatattt ttaatcaaaa
     1081 ttgacgtaac ttttaataaa tactacctaa ataaggtagt atttattttt gtgttttaaa
     1141 agaggaagtc caatatatct atgggaaact tcttaaatat tatgttggta catgaaaata
     1201 tacatccctg ctagactatt tacaacattt tactttgtac gtattcttgt tttaaaagga
     1261 atgggataaa atataggtac aataactatt tgatgctaaa tataattaat ggaggagaga
     1321 tagtgaacat acttaatgaa aaaagatatg tatggtttgc tggtaaaaaa tatattacta
     1381 ctttcaaaag attatccgag ttaatgcagc agactgttaa aagtgctatg cctgaaggat
     1441 acaagtttaa ttttgttcaa tcttcagtat ctactgaaag tatctatttt tcaattcttt
     1501 ctgagagtag gctttttcat tttagaataa gttctcatgt aaagaaaact gatgttgata
     1561 tatatacgtt ccgtacaaat aattataaaa atttaaatga tttgagtaga agtatcagtg
     1621 aatatctcaa ggggaatagc tatctcaaga ttcgattttc acatatatta attttactac
     1681 catatttgaa tgagaatttc accctaattc aagtagataa gtctttcatt gcctcaggta
     1741 atcaaggaaa tatgaatatt acaagtaaca aaacgtcacg tgtgctattg gcgttgatgg
     1801 gttacggaat tctttataga gatgaccaaa atggccagat tctaataaat cgggctgggc
     1861 gttcattatt aatgaaatat agaaaattta taccggaaga ttttcaaaac ttacagttag
     1921 aaaacatgcg tttagaagat ttatttagat tagcagaaga tgataagtat agatttgaag
     1981 ttttgaaaat tcaaaagaat gaactattga ataagttata tcctgagaat gcgataaaag
     2041 cacattttgg tgatgctaat catatgtata gttggttcat tcctaaaaga tttagaggga
     2101 aaatcaatgc tggagatcaa gtgaaagtac tcaatcgaaa tagtacagat gtcgtaatga
     2161 taacagatat ctatgtagaa gatgaagata taatcaaata tatgaagcct gtgataaaac
     2221 ttgttaataa aaataaagga acccgtggtg ctagttaatt ttttcctaga g
//
LOCUS       DACDAF010000164         2209 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.173, whole genome shotgun sequence.
ACCESSION   DACDAF010000164 DACDAF010000000
VERSION     DACDAF010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.173"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            504..1634
                     /locus_tag="IVZ69_002730"
     CDS             504..1634
                     /locus_tag="IVZ69_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HAP8184743.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            1865..2209
                     /locus_tag="IVZ69_002731"
                     /pseudo
     CDS             1865..2209
                     /locus_tag="IVZ69_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS982 family transposase"
BASE COUNT          674 a          366 c          437 g          732 t
ORIGIN      
        1 cacataaaac taaaaaatta tcaaagaatc ctggtgcaac tgaaagaatt tgcaacggga
       61 ttctttcaac ttatttgtta tttttttcta aaaaatatta aagattgtta aatttcacta
      121 tttcatttca aattccattg cctaatcatt aggaaaagtc tatcatgaac tcgtaaatag
      181 aatatagtaa taaccttgtt aggtgaggct cctatacaaa cataggctgt tgcccagaaa
      241 cgtcgaaagt cgccaatggg taaaacagaa actgttggat taaggctttt tccaatagct
      301 aagaatgttt tctttacgtt gtatagtgct aaaactcgga cgatgagatg atgctaggtc
      361 agaattcttg ttcgaaaagg tttctgacct tttctttata tttttgtgac tgacttattt
      421 gatgagacaa actcgctcct cacctgacaa gtggattgct gtgtgaggag gagatgcggt
      481 gaaaaaagat cgattggtgg attttgggtc cttatttgac tttgtccatg atcggtcttt
      541 tagaagtata cagtgccagt tcttatcgtt tattgcaagc cgatgaaaat acaaaaagtc
      601 tattattgcg tcaactaatt ttcatatttt tgagttggag cgtgatcttc ttagctcgtt
      661 cagtcaaact acactattta cttcacccta aaatagcagg atacggttta gccttatcga
      721 ttttcttttt agtattagta agaataggga tattcggtgt cactgtcaac ggcgcacaac
      781 gttggatctc tctgtttggc attcaattcc agccttctga actggcaaat ctttttttga
      841 ttttttattt aagctggttt tttcgtgacg gaaatagtag cccaaaagat ctaaaaaaac
      901 cattcctgat tacagtaggt ataacttttc tgattttatt tcagccaaag attgctggag
      961 cattgatgat cctttcgatt gcgtgggtca tattttgggc agcggcggtt ccatttaaaa
     1021 aagggatcta tctaatcgtt actttttctg cattgctgat tggagcagca ggcggggtat
     1081 tatatttagg aaataaaggt tggcttccac agatgtttaa tcatgcttat gaaaggatcg
     1141 cgactttaag agattctttt atcgatagtc atggtgcggg ctatcaaatg acccattcgt
     1201 tttatgcact atataatggt ggcatatttg ggcggggatt aggaaatagt atcacaaaaa
     1261 aagggtatct tccagagaca gaaacagatt ttattttttc gattattaca gaagagcttg
     1321 ggctaatcgg tgcattgtgt gtgcttttct tattgttctc attatgcatg agaatctttt
     1381 gtttaagcag tcgctgtaaa aatcagcaag ctggattgtt tcttttagga ttcggaactt
     1441 tgctattcgt tcagacgata atgaacgtgg gaagtatcgc ggggctgatg ccaatgactg
     1501 gtgtgccatt gccatttgtt agctacggag gaacaagtta tctgatcctt tctttaggaa
     1561 tcggaatcac gttgaatatt tcttcaaaga tacaggccga agagttggcg ctctatcgac
     1621 ctgaaaaaca ataaagagaa actgagaaac tctcagtttg aattatcata aagtacaatc
     1681 ttttattttt caagcgagag gttcttttag aaagaggaat tcgcaatgaa agtatctcaa
     1741 aaaatcatat tatacccgtg gtgctagtta attttttcct agaggaaaat gtctaaacat
     1801 gttggtaaat caacaaaaaa acgcatatag tagtctcaaa actcccaaga aatgaggact
     1861 acatatgcgt tcatcaaaat atactgaaca ttatacagat acttttataa cattcaagga
     1921 aattatgaga actgtttcta acatatacca caattgtgta ccagataaga ttaaaaaccg
     1981 aagaaatact gatcaactga agtaacgcga tacagtgatt attgcttgtg ttatatgggg
     2041 cataattaat ggctatacta gccaaagagc cacgtataga gcggtttgtt ccgtcttatt
     2101 tcctaatggt gactttccta gtaggagtcg attcactcgc ttaagttcaa acttagctta
     2161 cactatcaag attattcgat actttttcat caagaagctc accaaaggt
//
LOCUS       DACDAF010000165         2208 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.174, whole genome shotgun sequence.
ACCESSION   DACDAF010000165 DACDAF010000000
VERSION     DACDAF010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2208
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.174"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..370
                     /locus_tag="IVZ69_002732"
     CDS             <1..370
                     /locus_tag="IVZ69_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8184744.1"
                     /translation="PIENIRLVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAI
                     ARALVSDAPIILADEPTGNLDSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADI
                     ILELSGKKLKKVNKMNLEVE"
     gene            370..1746
                     /locus_tag="IVZ69_002733"
     CDS             370..1746
                     /locus_tag="IVZ69_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HAP8184745.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            1876..>2208
                     /locus_tag="IVZ69_002734"
     CDS             1876..>2208
                     /locus_tag="IVZ69_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HAP8184746.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT          862 a          272 c          403 g          671 t
ORIGIN      
        1 accaattgaa aatattagat tagtaaataa atcagcagat gaaagtatct tgtttgaact
       61 aggtttagat aaaaaacaaa taaaaagaaa tgttatgaaa ttatctggtg gacagcaaca
      121 aagagtagct attgctagag cattggtatc agatgctcca ataatactag ctgatgagcc
      181 tactggtaat ctagacagtg ttactgctgg agaaataatt aatatattaa agacattagc
      241 taaagataga aataaatgtg taatagttgt aacacatagt aaggaagtag cagattctgc
      301 ggatatcatt ttagaactaa gtggtaaaaa gttgaaaaaa gtaaataaaa tgaatttgga
      361 ggttgaataa tgataaaaaa tgcatttgct tatgtaacta gaaaaagttt aaaatcatta
      421 attatcatat tagttatttt atctatgtca actttaagtc tcattagttt atctattaaa
      481 gatgctacgg acagagcttc aaaagaaaca tttgctaata taacaaatag tttttctatg
      541 gagataaata gacaagtaaa tccaggaaca cctagaggtg ggggaaatgt aaaaggtgaa
      601 gatattaaaa agatatctca aacagatagt atagactcct atgtaaaaag aataaacagt
      661 gttgcagatt tagttgatta tgatattatt gaaactcaag agactcttgc gaatcaatca
      721 cctgaaagag caaagaattt taaaagaaca gttatgttaa ctggggttaa cgactcaaca
      781 aaagaaacaa aatttgtatc agaagcatat aaattagtag aaggaaagca tttagaaaat
      841 gaagataaaa ataaaatctt aatgcataaa gatttagctg aaaaaaataa ccttaaagtt
      901 ggagataaga taaaaataaa atctaattta tttgatgctg ataatgagaa aggtgcagat
      961 gaaacagtag aagtagaaat taaaggtcta ttcgatgggc ataatagcgg tgtagtaagt
     1021 gcagcacaag aactatacga aaatacatta atcactgata ttcatacagc tgctaaagtt
     1081 tatggtaata ccgaagatac agctgtatac caagatgcaa cattctttgt aaaaggtgat
     1141 aagaatcttg atagtgtaat aaaagatctt gggaaattag atataaattg gagagaatat
     1201 aatttgatta aaagttcatc aaattaccct gcattacaac aatctatatc aggtatttac
     1261 tcaatttcaa ataaattatt ttttggctca ttaatatttg caggagttgt agtttcatta
     1321 ttattattct tatggatgaa tgctagaaag aaagaaatag cagtattact atcattaggt
     1381 atatcaaaat tagaaatttt tggtcaattc ctaattgaga tggtatttat atcaatcccc
     1441 gcattcgttg gttcctattt cttagctcaa tatacagctg acaagcttgg gaataatata
     1501 ttgaataagg ttactggtga tatagctaaa caaatagcta aacaatctgc atctagccaa
     1561 ttaggtggtg gggcagaagc tgaaggattt aacaagacat tatcaagttt agatatcaat
     1621 gtattaccta aattcatgat ttatgtagtt atatttatga gtttagtact tcttgtatca
     1681 ttgattattt cttcattcaa tatattaaga aggaatccaa aagaattatt aattgacaat
     1741 aattaaaatt ttcggtgctt tttagcacca aaaatgagag tgtaatataa accgtgtaag
     1801 taaccatcaa tcctaggcgg gtggttgctt cacggttttt atttttctaa aataagatca
     1861 agaggtgatt acacgatggc tagaaagaaa agaaatcctg atgctgagaa gttagctgaa
     1921 tccattttga atacttatca acccgaatct gtagaggata tgcaagatgt tttaaaagat
     1981 gtgtttggtc ccttatttga aaaaatgctt caaggagaat tgaataacca tttagggtat
     2041 gacgcccatt ctaaagagcc aaagaaacat gacaatcgac gaaacggtta tggcaataag
     2101 acgcttaaaa cgagctttgg taaagtaaac attgatgttc ccagagaccg ggaggcttct
     2161 tttgaacctg agttgattcc taatagaaaa cgagatgtct ccgacatc
//
LOCUS       DACDAF010000166         2160 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.175, whole genome shotgun sequence.
ACCESSION   DACDAF010000166 DACDAF010000000
VERSION     DACDAF010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.175"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..>2160
                     /gene="acm"
                     /locus_tag="IVZ69_002735"
     CDS             <1..>2160
                     /gene="acm"
                     /locus_tag="IVZ69_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HAP8184747.1"
                     /translation="KKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVDP
                     TNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVGT
                     LTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATVN
                     VTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRLD
                     PSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRKI
                     MVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGEL
                     KIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVKE
                     KEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPSI
                     YFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGND
                     YVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQH
                     KEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNIS
                     IPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITNK
                     SKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKK"
BASE COUNT          849 a          348 c          417 g          546 t
ORIGIN      
        1 tgaaaaagtg tagaaatatt attttatcaa tgttatttat tattactaat ataacatcac
       61 tgattcctgt tcatgtctat gcggatgcag gcagagatat cagcagtaat gtcacttcgt
      121 tgaccgtgga cccaacgaat attacagatg gaggaaacat aaaagtaaaa ttctcgtttg
      181 acgaaaaaaa acaaaatatc caaccaggtg attatctttg gatcaattgg ccaagtgaag
      241 gaaatattcg cggtgaagga ttccaaaaag aaatcccatt aatgattgaa aataaaaatg
      301 ttggaacttt aacggtcaga aaagattctg cgcaggttgt gtttaatgaa aatattaaaa
      361 acctagactc agtagaaggt tgggggcaat ttgagataca ggccagaaac gtaaccgata
      421 ccggtgaaga aaatacggga ccattcaccg tgacgagcgg tgataaaaca gctactgtaa
      481 atgtgacaaa gccagcttct ggttcttctt ctagcgtttt ttattataaa acaggagaca
      541 tgctacctga agatactaag cacattcgat ggtttttgaa tattaacaat aacggcactt
      601 atgttgaaca accagttaaa atcagtgatg aaatccaaag tggacaaaga ttagatccaa
      661 gtacgtttga aattaatcaa atacacttag gtgaacagaa ggtttataga ggagaagagg
      721 gaatccaaca atttttacaa gatttcccca gcgctacatt taatttttca gtaactgata
      781 attacattga aataactata ccaaaaaact ttgtcaatct taggaaaata atggtgagtt
      841 ataagacgat catagaaaac ccagaacaaa taaattttga gaatcattcg gaagcttggt
      901 ttaaagaatt taataaacct gctgttgatg gagaaagttt caatcataca gttaaaaata
      961 tttcagcttc tggtggagtc aacggtacag ttagaggcga attgaagatt ttcaaatata
     1021 tcaatgacac agagattggt atcccaaatg tgactttcga attaagacga gcagatgaac
     1081 agcctattca aggacagtct agtatcctgt tgacttcgaa tgaacaggga gaagctagta
     1141 tcaaaggcct gcaagtagga gactatgttg taaaagaaaa agaagcaccc aattggattg
     1201 attttgatcc actaagttca aatgaactca aattctccat aaacgaaaat gatacagagg
     1261 gagtcagttt acctatttat aacaagaaaa aggttacgaa catcacagca actaaaattt
     1321 ggaacggtgg aaccactcca agaccgagta tttattttaa attattcaga gcaagtacaa
     1381 acaattggga accagttcct gatgcagaaa caaaacgatt agacaatgga ataacttcag
     1441 tgacttggga agatatccaa cagtatgatg atagtggaaa cgaatatacg tttaaagtgc
     1501 aagaagtaga tcaaaacgga aatgattatg tcccttcagg ttatcaaaaa attgaaaacg
     1561 ggctagtcgt tacaaatgag aataaagaag tcatttcagt ctcaggacaa aaaacatggg
     1621 aagacaatga gaaccaagac ggcaaacgac cgacgacgat cacagtaaat ctattagccg
     1681 acggtcaacc gatccaacac aaagaagtaa gtgaaaaaga tgattggcgc tatcgtttca
     1741 caaatctgcc aaaatacaga gacgggcaag aaatcatcta tactgtaacg gaagacaacg
     1801 tgcccgaata cagtacgacg attgacgggt ataacatcaa aaacagttat acaccggaaa
     1861 aaacaaatat atctatacca ggtagccata taacaccgtg gaaaaatttt ccagagaaga
     1921 cagagagaga gaaaattaga aatctattct ctcaaaaatt gcaaatattt gctcatacag
     1981 gagaatccag cgaacaaaga agcaattata ttagtaagag agctgtacct aaacagataa
     2041 caaataaatc aaaaagcatt cttcctaaaa caagtagtaa aaaatctagt tttgctgtaa
     2101 tcattggttt attgatagta actatctgtg ctgggatatt cttacaaaaa tataaaaaag
//
LOCUS       DACDAF010000167         2080 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.176, whole genome shotgun sequence.
ACCESSION   DACDAF010000167 DACDAF010000000
VERSION     DACDAF010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2080)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2080)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2080
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.176"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(9..1135)
                     /locus_tag="IVZ69_002736"
     CDS             complement(join(9..907,907..1135))
                     /locus_tag="IVZ69_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HAP8184748.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNTLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            1333..1647
                     /locus_tag="IVZ69_002737"
     CDS             1333..1647
                     /locus_tag="IVZ69_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184749.1"
                     /translation="MNSTFMAEDMYNMTLKKIKAYDHPLNLTLNNGLLSFVLAGYVDY
                     EYSPDYLEKPLQHENNDINFRFVYESKSKTWLVDQLSTINTSFHELPKPENEVEMVIK
                     IF"
     gene            complement(1877..>2080)
                     /locus_tag="IVZ69_002738"
     CDS             complement(1877..>2080)
                     /locus_tag="IVZ69_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prevent-host-death protein"
                     /protein_id="HAP8184750.1"
                     /translation="VLQEVVHSNSEIEITRDSKNGLNDGVIMISKRKWELLQEELYLQ
                     RTGTWAYVSDLMKNEKEDDFKVV"
BASE COUNT          644 a          367 c          305 g          764 t
ORIGIN      
        1 agagacggtt aagccatttt ttcttttgct aattcttcaa attcctgtgg ggttagatag
       61 tgaatcgagc tatggattcg atttcggtta taaaatcctt caatgtagct aaatagcgct
      121 cgatttgctt cttcaaaatc tgagtagcta gtcgtgtaga cttcttcttt tttcaatgag
      181 gcatggaaag attcgattcc agcattatca taaggtgttc cttttctact ataagaatgc
      241 cttattttgt tggttttaag ccattgttcc acttctcttg ctgtgtattg gctgcccaag
      301 tcagtgtgta gaatcattcc ttctggaatg tgataatgta tttttgcttt attcaatgtt
      361 tgaatgacac aatccacagt cattcgtttt gaaaatgtat aactaataat ttttttcgtg
      421 tgtaaatcca tgattgaaga taagtaacac caaccatttt tcttagtagg aatgtacgta
      481 atgtcagctg cccatttctc acagatcgtt tcagtagaaa agtcctgatt taagagattc
      541 tcttttgaaa tgatcggttt attagacctt tgaggtctat attttttaac tacaatcgac
      601 cttaaattta attgtttcat tagcttttgg acatgtttaa gagatactga aatcccttct
      661 tttaataaaa cttgatggat ctttgtggca ccatagcgtt gtttattcgt aaaaaaaatt
      721 gttgaaatct tctttttcaa cgtattattt ctgatttctg tagctgtcaa cggtttattc
      781 ttataaaaat aatagacact tctagggatt tctaataacc gacacaacaa agaaacagtg
      841 taatccttac accatttttc aataaattga acaagcgaat ttaggttttc cgagagaata
      901 tggctgcggc tttttttaag atttcaagtt cctcatttaa acgagcattt tcttttctca
      961 gttcagctac ttcttttcca gtcagtcctg tggactgatc aggtaaatat aaattcttcc
     1021 atttgtaaat cgttgcttca gataagccat attctttcgc taaccctcga acagaacgtc
     1081 cagtttgatt cagttcaaca atcatttgtt taaaattttc ttcatatcgg gtcataaaaa
     1141 ttcatcctct cgtagataag tttaatttat tcttgtctct acgaaaagct gtctaagatt
     1201 tgatactaac accagttagc aaaactttat actgaaaaag ttgaacaatt ttttaagtct
     1261 ggtgccaata aagacttttc aaaaataagc gattattcgg agaacttttt taatgaaacc
     1321 caagatgaaa tcatgaactc aacttttatg gctgaagata tgtacaatat gacattaaaa
     1381 aaaataaaag cttacgacca tccgttaaat ctgacactaa ataatggact gctttctttt
     1441 gtattagcag gttacgttga ctatgaatat tcaccagatt atttggagaa acctcttcaa
     1501 cacgagaaca atgatattaa ttttagattt gtctacgagt caaaaagtaa aacatggtta
     1561 gttgatcaat taagcacgat aaacacaagc ttccatgaat tacctaaacc tgaaaatgaa
     1621 gttgagatgg tcattaaaat cttctaaaaa agaagcgttg aaggagaaat attcctttca
     1681 acgctctttt ttatatgctt agaaacataa ataaattgta tactttcttt ttagccccta
     1741 ttacttttca cgaaaaatat ctttttttcg acgctagcgt ttctctactt ctaatactgt
     1801 acacagtttt tgtattattg aaaaattact cattatttag cattaatcca catcgtttta
     1861 tcaatcgacc ttcatactaa actactttaa agtcatcttc cttctcgttt ttcattaaat
     1921 cagatacata agcccatgta cccgttcgtt gtaaataaag ttcttcttgt aacaactccc
     1981 attttctctt agaaatcata atgacgccat cgttcaatcc atttttagaa tccctagtaa
     2041 tttctatttc agaatttgaa tgaactactt cttgcaacac
//
LOCUS       DACDAF010000168         2058 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.177, whole genome shotgun sequence.
ACCESSION   DACDAF010000168 DACDAF010000000
VERSION     DACDAF010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.177"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            368..1948
                     /locus_tag="IVZ69_002739"
     CDS             368..1948
                     /locus_tag="IVZ69_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HAP8184751.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
BASE COUNT          684 a          353 c          439 g          582 t
ORIGIN      
        1 aataaacaag caacacgtct tttcttttag tcagctgaca aaaaaatatt tgactcttat
       61 ggtttggtgg ctttttcatt cgctgaatcc atgctatact gattcagttg tagtagttga
      121 caaaggttgt gaaaaagcta tcctgcatta agtaataaga gcagccaagc aaaaacagct
      181 tttcgtattt ttggcttggg tgggcttatt gctgataggc tgtctctaga acgccgttta
      241 ctcggaaaaa gagactgcta cacggctttt gtcacagccc tatatgaaat tgtctttctt
      301 taagagatcg gacaatctgt gcctagagaa aatataaata attgaatgga agaaatggag
      361 ttaggttatg aataatccaa aattaaagca acaagtggac aatcgcagaa cttttgcgat
      421 catttcccat ccggatgctg ggaaaacaac gattacagaa caattactat tgtttggtgg
      481 ggctatccgt caagccggga ccgtaaaagg caaaaaaaca ggtaattttg ccaaatcaga
      541 ctggatggaa atcgagaaac aacgtgggat ttctgttact agttctgtta tgcagtttga
      601 ttatcaaggg aaacgagtaa atatcttgga tacaccagga catgaagatt tttctgaaga
      661 tacttatcgt actttgatgg ccgtggatag tgcggtcatg gtaatcgata gtgcaaaagg
      721 gatcgaagca cagacaaaga aattattcca agttgtaaaa aaacgtggca tcccgatatt
      781 tacttttatc aacaaactag atcgtgatgg tcgtgaacca ttggaattgt tagaagaatt
      841 agaagagcta ttagatatcg aatcttatcc gatgaattgg ccaatcggta tgggtaaagg
      901 gctagaaggt ctttatgata tctaccataa tcgtgtagag ttttatcgtc cggaaaatta
      961 tcaggatgaa cgattagtag aattggatga agatggactg cttcccgaaa atcatcctct
     1021 aactgaaaat tccttatatg aacaagtctt agaagaagta gaactaatca aagaggctgg
     1081 agatgcattt aatcaagaaa aaattgctcg tggcgatcag acaccagtat tttttggttc
     1141 tgcattgact aacttcggtg tacagacttt tttagagact ttcgttgaat tggcaccagc
     1201 tccttatgga cacaaaacac aagatgatca gatggtaagt ccttatgagg aagaattttc
     1261 aggtttcgta ttcaagatcc aagcaaatat gaatccagcc catcgtgacc gaatcgcttt
     1321 tgtccgaatc tgttctggaa cattcgaacg aggaatggat gtctggttgg aacgtacaaa
     1381 taaaaaactg aaattaagca atgtcacaca atttatggca gattcgagag aaaacgtcga
     1441 aaaagcagta gcaggcgata tcatcggtgt atatgataca ggcaattatc agattgggga
     1501 tacattgttc gaaggaaaac taaaagttgc ttatgaagaa ctcccttcat ttactccaga
     1561 gctgtttatg aaagtgactg caaaaaatgt catgaaacaa aaatccttcc acaaaggaat
     1621 ctatcaatta gttcaagaag gagcgattca gctttataaa acatatctaa cggaagaata
     1681 tatcattgga gctgttggtc agctacaatt cgaagtattc caatatcgta tgttaaatga
     1741 gtataacgcc gaagtaatca tgtctccaat gggacacaaa atcgctcgct ggatcgatcc
     1801 agaagatttg gatgagaaga tgagttcaag tcgcaatatc ttggctcgtg accgtttcga
     1861 ccaaccgttg ttcttattcg agaaccaatt tgcagaacgc tggtttgcgg ataaatatcc
     1921 caatgtaaaa ttaaaaagtt tgatgtaaag aagtcttgac acaagctgcc ctgcatcaag
     1981 taataagaat agccaaacaa aaacagcctc tcatattttg tttagagccg tgacggattt
     2041 tccgtgacgg ctcttttt
//
LOCUS       DACDAF010000169         2056 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.178, whole genome shotgun sequence.
ACCESSION   DACDAF010000169 DACDAF010000000
VERSION     DACDAF010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2056
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.178"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            493..714
                     /locus_tag="IVZ69_002740"
     CDS             493..714
                     /locus_tag="IVZ69_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184752.1"
                     /translation="MRVIKSEKFTLAEIMTTSELAQELDYNQAYVLRLAKEHLTEGKE
                     YRSAGRRNYLFSPEALKKLEKVITTKEGE"
     gene            715..972
                     /locus_tag="IVZ69_002741"
     CDS             715..972
                     /locus_tag="IVZ69_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184753.1"
                     /translation="MPKETTINVEQLEKLLESYSNDFIELTGGKVEETTDLFDLLLTN
                     ILELNSEEQKEHKGKLIAPSYRKAAKSAVPTGFLTKQPYIF"
     gene            complement(1108..1710)
                     /locus_tag="IVZ69_002742"
     CDS             complement(1108..1710)
                     /locus_tag="IVZ69_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HAP8184754.1"
                     /translation="MTSRKTKDERTRNWTFVVYPESAPENWREFLDELHVPWVESPLH
                     DKDVNPDGELKKPHWHVLIMFSGKKTYDQIREITQKIRSPNPQKCANAKGMVRYFAHM
                     DNPEKFQYAKSDIIAHGGAEIASYLSVTSAERYELIREMMSFVDSKNITEIKDLIDYA
                     MSERFDDWFPLLCDNSAYIIGQYIKSNRHGGSVNSKINKG"
     gene            complement(1777..1932)
                     /locus_tag="IVZ69_002743"
     CDS             complement(1777..1932)
                     /locus_tag="IVZ69_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010001600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8184755.1"
                     /translation="MISNEKKRVVVTLTKEVADNLDKIAKQMGLSKSGLITIWVNANG
                     KENEQKK"
BASE COUNT          678 a          464 c          313 g          601 t
ORIGIN      
        1 aaaaaaaaac gctgaaaccc ttgggagagt aaggctaaac agctatcgac caatgaccaa
       61 tgaccaataa ggggggtgtc gtagtccccc cctcctccgc ccaattcata aacaccaaaa
      121 ccaaaaaaca aacctcaggg ctccgccccg aaccccgacc tccttctacc gaaatatatg
      181 caggcgccac gcttactatt tcgttcagct atcggctttt gcaatctaac acgaccgttt
      241 cgctaccagt cgccttacag gctccattct cgcttctctt acgtgtttta acgattgcgc
      301 cgataactaa acgaaataga cgctaaatcg cttaaaacgc aaaatagacc ctttttagag
      361 cattgatttt ttctactagt catttcgata atataaaatt gaccacaaca cagaaaactt
      421 atattataag cttatgtcgt aagtccgacg tactcacgta atatagacgg acgttaaatg
      481 gaaggagcat aaatgagagt gataaaatca gaaaaattca ctttggccga aattatgacg
      541 accagcgaac ttgcacaaga acttgattac aaccaagctt acgttttgcg cttagcgaaa
      601 gaacatctga ctgaaggaaa agaatatcgc tctgccggta gaagaaacta tcttttcagc
      661 ccagaagccc ttaaaaaact agaaaaagtc ataaccacca aagaaggtga gtaaatgcct
      721 aaagaaacaa ctatcaacgt tgaacaacta gaaaaattgc tagaatcata ttccaatgat
      781 tttatcgaat tgaccggcgg aaaagtcgaa gaaaccaccg acctctttga cctacttctc
      841 acaaatattc tggaattaaa ctctgaagaa caaaaagagc ataagggaaa actgatagca
      901 ccttcctaca ggaaggcggc taagtcggct gtgccaactg gttttcttac aaaacaacct
      961 tatatttttt gatatcacaa aaaaatccat tttggaccta ttttcggtca taatatagta
     1021 cctacttttg gtcatagttt cgtccgtagt tttggtcata gtgactaaga ctttcacgca
     1081 caaaaaaaga gctgaaatta acagctctta tcctttattt atttttgaat ttacacttcc
     1141 accatgacga ttcgatttta tatattgccc gataatataa gctgaattat cacaaagaag
     1201 cggaaaccaa tcatcaaatc tttctgacat tgcatagtca attaaatctt tgatttcagt
     1261 gatattctta gaatcaacaa acgacatcat ctctctaatc aactcatatc gttctgcact
     1321 cgttactgac aaataactag caatttctgc accaccatga gcgataatat cacttttagc
     1381 atattgaaat ttttctggat tatccatatg agcaaaatat cgcaccatac cttttgcatt
     1441 agcacatttt tgcgggtttg gagaccgaat cttttgagtt atctcacgta tttgatcata
     1501 cgtcttttta ccgctaaaca ttatcaaaac atgccaatga ggctttttca attcaccgtc
     1561 aggattcaca tctttatcat gaagtggact ctcaacccaa ggaacatgta actcatctaa
     1621 aaactccctc caattttcag gagccgattc aggatagact acaaacgtcc aattccttgt
     1681 gcgttcatct ttagtttttc tactcgtcat gctataatca ccttaattga acaacagtct
     1741 aacagcaaaa gcagtgcgcc aacactaatg cttttgctat tttttttgct cattttcctt
     1801 tccgttagca ttaacccaaa ttgtaataag accagactta ctaagaccca tttgtttcgc
     1861 aattttatca agattatctg ccacttcctt agtaagcgtt acaacgactc tctttttttc
     1921 attactgatc ataattcgta tcctccaacg actttttctt aaaaaccata gtaacaaaaa
     1981 agtaactaag gtgcaacagt ttagatacta attagcgaat aataggcctt aaacccttgg
     2041 cattactgat tttgtc
//
LOCUS       DACDAF010000170         2052 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.179, whole genome shotgun sequence.
ACCESSION   DACDAF010000170 DACDAF010000000
VERSION     DACDAF010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2052)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2052)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2052
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.179"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..2050
                     /locus_tag="IVZ69_002744"
     CDS             <1..2050
                     /locus_tag="IVZ69_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HAP8184756.1"
                     /translation="FNPKTVLAIGTFAASLSLAGSVDAASTNVMYRLYNPNNNEHFYT
                     SSKKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWLTKN
                     YGWTYEGPAWRSAEKNNKPIYRLFLPGVKSGSHHYTASWKEVQWLTKDYGWKYEGIGW
                     YGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKATQKQ
                     VDSAKNKLDSAYKGLKKKPVPTVNKAELQALYNRVKSTAKGDFTEESWNNFQTALSNA
                     KKVLDDSKVSQTQVNNAKNSLDAAFKGLQHKPETPKEYTVTINHIDNQTGQVIATDQA
                     KVTSGSTYTAKAKAFKYSEGAKDNFSYKVIGNDTQSKTITGNTTITFNYNQVHQINLL
                     CNNNYKNEGRVNILKEQIVNVTHGDSVTLTAPSIQGYVLDDRVEPTNSVTLNNVTESQ
                     NYIFNYTRKFNVTVNHVNADTNAVLSSESKTVYEGDSFATPWKNMTDQNYFLCRNDDP
                     TVTVDKNGQRSINNVDQNKTITFKYKKISLDELRNFMRQKELAWLNDYRQQNGVAPMQ
                     FNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENISQTGLYIDDLL
                     SDDGAIDAMVGWKNSPAHNANLLYNNQSILGLGHNFVVDSAGRIGVDNVFISANPIFK
                     "
BASE COUNT          734 a          382 c          377 g          559 t
ORIGIN      
        1 atttaatcca aaaactgttt tagctattgg aacatttgct gcctcactta gtcttgctgg
       61 atctgttgac gctgcttcaa ctaacgtcat gtatcgcctt tacaatccaa ataataatga
      121 acatttttac acctctagca aaaaagaacg tgaccatcta gtaaagataa aatggggaaa
      181 ttatgaaggc cccgcctggg aagcaccgac tagcggtggc catcttgtct atcgtttgta
      241 caataaaggt cttcgtgatc accattacac agctagttgg gatgaagtga aatggttgac
      301 taaaaattac ggctggactt atgaagggcc tgcctggcgt tctgccgaaa aaaataataa
      361 accgatctac cgccttttcc ttcctggtgt aaaatctggc tcacatcact acactgcaag
      421 ttggaaagaa gtacaatggt taaccaaaga ctatggctgg aaatacgaag gtatcggttg
      481 gtatggcgct gacacctcta aacccaaagt gaataaatcg gctctagaag ctctttatac
      541 gagcgttaag ggaacgaaaa aaggtgacta taccgacaat acctggaacg cattccaaac
      601 cgctttaaac aatgctaaga aagtgttaaa tgactcaaaa gcgactcaaa agcaagtgga
      661 tagtgccaaa aataaattag attctgctta caaaggatta aagaaaaaac cagttcctac
      721 tgtgaataaa gctgaattac aagctttata caaccgagta aaatcaactg ctaaaggaga
      781 ttttacagaa gaatcttgga ataattttca gactgcttta tccaatgcta aaaaagtact
      841 agacgattct aaggtttctc aaacacaagt aaacaatgct aaaaatagtc ttgatgctgc
      901 atttaaaggg ttgcaacaca aacctgaaac accaaaagaa tatacggtta ctattaacca
      961 tattgacaat caaacaggtc aagtgattgc tacagatcaa gcaaaagtaa cttctggttc
     1021 tacttacact gctaaggcaa aagcatttaa atatagcgaa ggcgctaaag ataattttag
     1081 ctacaaagtg attggtaatg atactcaaag caaaacaatc acaggtaata caacaatcac
     1141 attcaattat aatcaagtgc atcaaatcaa tttgttgtgc aataacaact acaaaaacga
     1201 aggacgagtt aatattttga aagaacagat agtcaatgtc actcacggtg acagtgtcac
     1261 tttaactgct ccttctattc aaggatatgt tttagacgat cgggtagaac caacaaattc
     1321 agtaacctta aacaatgtga ctgaaagtca aaattatatt ttcaactaca ctcgtaaatt
     1381 taatgtgact gttaatcatg taaatgctga taccaacgct gttctctcta gtgaatcaaa
     1441 aacagtatac gaaggggata gctttgctac tccttggaaa aacatgactg atcaaaatta
     1501 tttcttgtgc agaaatgacg atcctaccgt taccgtggat aaaaacggcc aacgatccat
     1561 taataacgtc gatcaaaata aaacaatcac attcaaatat aaaaagattt cattagacga
     1621 attacgtaac tttatgcgtc aaaaagaact tgcttggtta aatgattatc gccaacaaaa
     1681 tggtgttgcc ccaatgcaat tcaatgatat tgttcaacag gctgcagata ttcgagctaa
     1741 agaattacaa gtcagcttca gtcactatcg ccctggtggt ggtactttcc aagatttatt
     1801 ggaaagctta ggctgctacg gtgctaaggg agaaaacata agtcaaactg ggctgtatat
     1861 tgatgacctt ttatcagacg atggtgctat cgatgccatg gtaggatgga aaaatagccc
     1921 tgcccataat gcaaatttac tttataataa ccaaagtatt ctcggattag gtcataattt
     1981 tgtagttgac tctgctggta gaattggcgt agataatgta tttattagtg cgaatccaat
     2041 cttcaaataa aa
//
LOCUS       DACDAF010000171         2003 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.180, whole genome shotgun sequence.
ACCESSION   DACDAF010000171 DACDAF010000000
VERSION     DACDAF010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.180"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..378
                     /locus_tag="IVZ69_002745"
     CDS             <1..378
                     /locus_tag="IVZ69_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HAP8184757.1"
                     /translation="KNVSTEDFFNYCRLEESGVTVTSGTDLPLFITDIPESIIRAVFR
                     RFPEGEEVWEKETSFTTTELLKSFTSNSFKVNGLSEYGEIKVGKSASLAVFSEDLCTD
                     DWQKVMAAEVIATYLDGDLVYKK"
     gene            426..1826
                     /gene="yfcC"
                     /locus_tag="IVZ69_002746"
     CDS             426..1826
                     /gene="yfcC"
                     /locus_tag="IVZ69_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HAP8184758.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            1859..>2003
                     /locus_tag="IVZ69_002747"
     CDS             1859..>2003
                     /locus_tag="IVZ69_002747"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HAP8184759.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAF"
BASE COUNT          555 a          339 c          432 g          677 t
ORIGIN      
        1 aaaaatgttt ccacagagga cttctttaat tattgtcgat tagaggaaag tggtgtaaca
       61 gtcactagcg gtacagattt accgctgttt attactgata ttcctgaatc gattataaga
      121 gcagtattcc gtcgttttcc tgaaggagaa gaagtctggg agaaagaaac aagcttcacg
      181 acaaccgagc tgctgaaaag ttttacaagc aacagcttca aagtaaatgg tttatcggag
      241 tacggagaaa taaaagtagg gaaaagcgcc agcttagctg ttttcagcga ggacctctgt
      301 actgatgact ggcaaaaagt gatggctgcg gaagttatcg ctacctatct tgatggtgac
      361 ttagtttaca agaaataatg cttttcgata taacgttata aaacgaatta aagagaggtt
      421 aaaaaatgga aacaatgaaa agaaaattca ccttcccaca tagttataca ttgattttta
      481 tcttaattat tttggctgca attttaactt ggataattcc tagtggtcag tttgagacag
      541 ttgttgaaaa cgtcgcaggt atggaaaaaa caacggttgt tccgggaacc tatcaccaaa
      601 tcgataaggc agattatgga caaggttttt cctctatact aatggcacca gctgaaggga
      661 ttatttcagc tgttgaggtt gttgcttttg ttctcatcgt tggtggtgcc ttcgggatta
      721 tcctaaaaac gggagccatc gatcgagggc tgtttacctt agcaaaagtt ctgggagaca
      781 aggggatctt agttattccg atgtcgatga ttctattcag cttaggagga tcaacctttg
      841 gcatgagcga ggaagtcatt cccttatttg cggtgtttat ttctctgatg ttttctcttg
      901 gctatgattc catgactgcg atcttgattc tatttttaag tacacaagcg ggatatgttg
      961 ggtcgacgat taatcccttc aacgttttaa tcgcacaggg agtagctggc gtttacggaa
     1021 atcccctgct ttggtttcgg atgctatcct ggattgtcat tactgggatt tcaattgttt
     1081 tcaccatgct ttatgctagc agagtcaaaa agaatccact gtcctctatt gtttatgaga
     1141 gtgatttaaa ggttaagcat aagtttcaaa attttgacac tgaaaaagag ttttcaacac
     1201 aagataaact aattatcgcc ggttttatcg taggtttagg aatcatgatt tggggtatca
     1261 tttccaaggg atggtatatg gttgaaattt ctgcactatt cttaggatta ggtctttttg
     1321 ctgggggcat cgctagattt tctcaaaagg aaattgctga agcttttgtc gaaggctgtt
     1381 cagatttcgc ctatgctgct gtaatcattg ggctagctag aggagtcttg gtaatcttgg
     1441 aaggtggaat gattattgac actattctaa acagcttggc taacctttta ggtggtcttc
     1501 caaaattcct gttcactacg attctactca tttctcaagt aattgtttcc ttttttgttc
     1561 catcctcctc aggagctgcg gcattaacga tgccggttat ggcaccattg ggtgatctaa
     1621 tgaatgtaag tcgtgatgtt gttgttctaa gtaaccagtt tggaaatggt ttaatgaata
     1681 ttatctcccc aactagtggt gtattactgg caggattagc catcgcagag attaatttct
     1741 ctaaatggtt taaggttggc ttcaaaatat ttgccatctt aacccttgtt tctgctgttt
     1801 tgttatacat tgctacactc ttttagtctt aatcatccat taataggagg caatagttat
     1861 gattaaaata aatcaattag caggaatgaa tatccactat ttattttatt ctctcaaaga
     1921 atttttcgct tatcaacaga aaattggtat ttcttctgtt gaactttggg gaggtgctcc
     1981 gcattttttc atagatgctt tta
//
LOCUS       DACDAF010000172         2002 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.181, whole genome shotgun sequence.
ACCESSION   DACDAF010000172 DACDAF010000000
VERSION     DACDAF010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.181"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            16..567
                     /gene="lepB"
                     /locus_tag="IVZ69_002748"
     CDS             16..567
                     /gene="lepB"
                     /locus_tag="IVZ69_002748"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HAP8184760.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(650..1192)
                     /locus_tag="IVZ69_002749"
     CDS             complement(650..1192)
                     /locus_tag="IVZ69_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HAP8184761.1"
                     /translation="MNTLIAKDVFRLPEMNARLLSTSALLLALDVILYKIAIGPAYFQ
                     ITFGFLSMALMGYLYGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLF
                     LYHKKINLPSVIAAQLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQI
                     MVVYSFIKTLEARKVFKRAV"
     gene            complement(1429..1827)
                     /locus_tag="IVZ69_002750"
     CDS             complement(1429..1827)
                     /locus_tag="IVZ69_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HAP8184762.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
BASE COUNT          707 a          349 c          331 g          615 t
ORIGIN      
        1 atggattgat agagattgac aaaaaaacaa cgctatatta atcgcttctg gcttgtattc
       61 aaatacttac ttgtttctgt attccttgcg ttcatgttgc ggggattttt attcatcccg
      121 gtaccagtgg aaggcaattc aatggaaaac gtgttgaagc aaggtgatat ggttgtgatg
      181 gaaaaatttt cggagatcag acgatttgat attgttgttt ttcaattagc agatggcacg
      241 atttatatca aacgagtaat cggtcttcca ggagaaaatg tcagctacca aaatgatcaa
      301 ttgaagatca atgggaaagt agttaaggaa ccttatctaa ctaaaaacct gaaatcagat
      361 catgcaaatg catcctatac gacggacttt acactacaag agctaacggg acaatccaag
      421 cttccggaag ataattattt tgtacttgga gataatcgaa gagtttcaaa agatagtcgt
      481 tcgtttggca cgatcaataa aactgatatt ctaggtaaag caagatttgt ctattatcca
      541 cttgatgaaa taaaatggat ccagtgagaa acaataaagc gtgcagtctg ttgagactgc
      601 acgctttatt gtttaatcca aaatcagttt actaccttag tacgtaaaat caaacagctc
      661 gtttaaacac ttttctagcc tctaaagttt tgataaatga ataaacaacc attatttgaa
      721 tagggatttg gatcatattc ctgatgaatc tacctagaaa aattactttg aaatctgcac
      781 caaacaaaac agacatcagc caagaattga taaaaaggct gactgggatc ataatcaata
      841 attgggcagc gatgacggaa ggcaggttta tctttttatg atataaaaat aagccattaa
      901 taaatccacc aaggaaagcc gtgataagaa aagcagcttg aaacgttcct gaaccaaata
      961 tcgtgaaatt taaagtgttc gacaacattt caagcaaacc agcccagatc ggtccatata
     1021 gataacccat aagcgccata cttaaaaatc cgaatgtgat ttgaaaataa gcaggaccaa
     1081 tcgctatctt gtataagatg acatcaaggg ctaataaaag agcagaggtc gacaacaatc
     1141 ttgcattcat ttcgggcaat ctaaaaacgt cttttgcaat caaagtgttc aaaatattct
     1201 ctcctttgtc agttaataat aaaaggatac cataaaatca ccaatgtgtc atgacacatt
     1261 ggtgatttac atacactggc atctaacaat taaaaaaagg gtgagaagac tgcttttata
     1321 aactgtaaaa aagagattgt acgaataaaa aaaatagagg cggagaatac ttatcgtatc
     1381 atccgccttt gtttttttgt tataaaaaac gtcagattag ttatctgctt acatcttcat
     1441 ccatacgggt tctaatgtat ttccgtctag atcttggact tctaatgaaa acatttcttc
     1501 ttcaggcatt cccatatcta cttcgtggaa agtaccacca ttttcttttg caatttgagc
     1561 aaattttttt acttcatccg cattttcaac actaaacgaa atcaaagcac cacttgtttt
     1621 tttattatca gctatttctt tatcttttat aaatttttta taaaaatcat gagagagaag
     1681 cattatccaa aaagtgtcat cccataccat tgaaccagct tcttcagtag aaaattcttc
     1741 atttttttta aaacccagct tttcataaaa agcaacggaa cgattgacat cagcaacagg
     1801 aaaattaaca aaaaccatac tattcatttg tttcgtctcc tttctgtttt gttcgtctat
     1861 catctcttat ttaggaaacg ctgtcaaaaa tttagattca tatatagaaa ccaaaataaa
     1921 aatttgcatc atcaaaaaag tgaagatgtg atagaatgag gactggttca ctttcactta
     1981 actaatagat ggaatttctt ta
//
LOCUS       DACDAF010000173         1996 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.182, whole genome shotgun sequence.
ACCESSION   DACDAF010000173 DACDAF010000000
VERSION     DACDAF010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1996
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.182"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            609..941
                     /locus_tag="IVZ69_002751"
     CDS             609..941
                     /locus_tag="IVZ69_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HAP8184763.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            1560..1901
                     /locus_tag="IVZ69_002752"
     CDS             1560..1901
                     /locus_tag="IVZ69_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HAP8184764.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT          690 a          269 c          422 g          615 t
ORIGIN      
        1 tgcatactcc ttttttttga gttataataa tacgcgaaga gagataattt cattatttaa
       61 acaagctaaa aatcttgata ttacttcttt tcaggcaata cgaatattat tcgcttacat
      121 tttttgtata aatttaattg tctgctatgc ttgtgatgaa ttgattttcg ttttgcactt
      181 ttggatgata aatttggaca attgaaaata caaaaaaaag aaaggcggta tgaactcgga
      241 aggctggtaa ccttcgtcag cgttcataca cggcattaag atttggccct taatgcgtta
      301 acctttcagt gttacggtat tacccgcaat ggatttagta taacagatat tcaaaagtga
      361 taccactttt tttggctgtg ttaaggttaa aaatacgtga tattacgatg aatctatgcc
      421 taagcataat gttataaaaa tgtccgtgtg gctctttgcc gtatgacgaa cgctgaaatt
      481 agagggaacg catgtttgga tgcgttccct cttttttgtt tgtcatgaac gaaaatcaat
      541 tctctatttt tgaaaaataa caagaaaaac ttgttaaaaa tatttaaaga aattgggtgg
      601 tttattttat gtcatataca ggaattttga gtctcaaaga tatttgtcac tacggtaaac
      661 ggtgtaccgc tacagagaaa atcacgaaga aactatcaac tggccaaagt aaaaccgttg
      721 tgcagtgtaa gaaatatata atccagaaag acaaagtctc agaggaaatg atttattaca
      781 ttgggaaaca aaagcaaata attttaaaag atcctatccc cttaaaagag ctatatccaa
      841 caatcaaaca tgtttatgac caaaacggtg tactgattgg tcgaagaaaa aatggagtct
      901 tgcgttgtac cgcaaaaggg atggggcgtt tgatcggctg aattgatcat tctcataact
      961 tgtattttat cgtttttcgc ttgcttgaaa atattgtcga gacttctaaa ggaacttaga
     1021 gtcactagaa aaataaggag tagacttgat ctatcaacaa ttcccttcgg ggagtgacgg
     1081 ggtaggtttt aacgattggt aacgtaaaaa attggtcaat cgagtaaatg cgcttgtttg
     1141 gatagtggtg aaatgaattt gtgtaaataa taagcgcaga gtaaacaaga gggaatttag
     1201 aagttagaca agttagaata gcgtctagat taatcatgag cagctactaa gggatctaga
     1261 ctttgacgca aactcatgga ataaggagta ggtcttctcg taatggggag gacgcacaag
     1321 aaattgtgtc gtgtgctgca gtacatgtag atacttgcga ggacgttgat tattggatca
     1381 atcgagcatt taccgctgtc tactagggtt tctcgtttcg gacgccataa acgagtcgaa
     1441 attttttatg tatttttaag taaacgaaaa acgataaaat atgaacaagt cctgaataaa
     1501 gtgaaaaaat taatataaag catagagaaa atgaaattta cgtaatggag gaatgacaaa
     1561 tgaaaaatta tgatccgaat atacgattgg gcacacatac tattaaggtt tctttccaac
     1621 gttgggatta caaaggattt gtgacgttta gaaggggcgg aaattgtaaa ggattagatg
     1681 ttttagcatt agacgaggat gatttatacg atcaaacatt gactgataat ccaattggat
     1741 tcggcttgct acctgaagat gatgaaggta atgaatggtt taaaatgacg cttatgaatg
     1801 ataatggaga cgaattatct gttgaagata cttggtcata tttgagtgat tatattgtca
     1861 gctttgaaat cattgaattt gtagcggata aagaagaata aaaactggag gaataaattt
     1921 tacagataaa ggcttagaag gagtcacgac gattaataaa aaggtagtat taccttaggc
     1981 attgagtaag gaattt
//
LOCUS       DACDAF010000174         1991 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.183, whole genome shotgun sequence.
ACCESSION   DACDAF010000174 DACDAF010000000
VERSION     DACDAF010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.183"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            273..839
                     /gene="amaP"
                     /locus_tag="IVZ69_002753"
     CDS             273..839
                     /gene="amaP"
                     /locus_tag="IVZ69_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HAP8184765.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            852..1040
                     /locus_tag="IVZ69_002754"
     CDS             852..1040
                     /locus_tag="IVZ69_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HAP8184766.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1053..1610
                     /locus_tag="IVZ69_002755"
     CDS             1053..1610
                     /locus_tag="IVZ69_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HAP8184767.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1642..1884
                     /locus_tag="IVZ69_002756"
     CDS             1642..1884
                     /locus_tag="IVZ69_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HAP8184768.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          724 a          308 c          406 g          553 t
ORIGIN      
        1 aataaataga atcttgtaat aataactgag cataatcttt gcaattttta atcttgaata
       61 atatccttta agtatagcca gcaatcaaaa gtaaatagag aataagtaag caattgttat
      121 ttcagtatca gactggcaat aaaacgccgt tatgatccag caatgtttgg tagcgcttta
      181 tttactgatg ctatgctaac tgttcgctat ctatactgtg attgtcggta gagttattta
      241 cagggtaaaa ataagtttat aggaggtgga aaatgaataa ggggttaaaa ataatcggtg
      301 ttatcatgag tttactgcta ctttcagtat ttctagcgat tgcgttgatc aatgcgccgt
      361 atattatgcc tgaacaattg gaacgatttc gcttctttac tttaacgaat tactacatgc
      421 aacaatatat tttctgggca gctgtagtat ttgccgttct tgctattatc atcttgctag
      481 tcgttctttt ctatccaaag tcaagaggaa ctttcgttat gaaacgggaa gatggcaaac
      541 taacaatcga caaaaaagcg atcgaagggt tggtacgttc ccatttacac gaagaagagt
      601 tcattcattc acctaaagta cggatacgtt caacgaaaaa tcgaatccat atccatgtca
      661 acggagactt gaaacgaact tcttcattag tagggaaaac aggtgtattg atgcaagata
      721 tcgaagaaga agtaactaaa gtactcggaa caaaagaaac ggtcaaagtg gcagtcacat
      781 acagcggtta tgaagaacaa gaagatacaa gagactacaa gcactctcga gtggaatagg
      841 agggccaaat aatgaaagaa ctattttcag catacaagct ccctattatc tttgggggtc
      901 ttggactact gctagctgtt ttatggttaa cgattggatt tttcaagaca ttgttgatca
      961 taatcatgac agcaattggc gcaggaatcg gtttttattt gaaacagtca ggaatagttg
     1021 atcaattttt taaatcatag gaggaaacaa agatggaaaa caaaaacatg aatacaacaa
     1081 atggatcagt tttggcaaat gaaaaaggag aaaaccgcat gatgaatggt gaattgactt
     1141 atgaagacaa agtcatccaa aaaatcatcg gttatgcatt gaaagatgta gatggtctat
     1201 tgacattaga tggcggattt ttctcaaata tggctgaaaa attagtcaac acagataacg
     1261 taacagcagg tatcaataca gaagtaggta agaaacaagt agctgtggat ctagatgtga
     1321 tcgtagaata cggtaaagac atcgaagata tttacaacca aatcaaagaa ttgatcagta
     1381 ctgaagtaaa caatatgaca catttagatg ttatcgaagt gaatgtgaat gttgcagaca
     1441 tcaaaacaca agaagaatac caaaaagatc aagaaacagt acaagacaaa gtaacagaag
     1501 cagcaaaatc cacaggacaa tttgcttcac gccaaacaga taaagcaaaa tctgctgtag
     1561 gcaaaggtgc acaaaaagtc aaagaaaata acgaaccacg tgtacaataa gaagtaagaa
     1621 gtcagttagg aggaatttaa aatgggattt atttgggcat taatcgtcgg cggtatcatt
     1681 ggagcaattg caggagcaat cacgaataaa ggatcatcaa tggggatcat cgcaaacatc
     1741 attgctggtt tagtaggttc agcaattgga caagctttac taggaacttg gggaccaaca
     1801 attgcaggaa tggctatcat tccatcattg atcggtgcaa tcattttagt attagtcgtt
     1861 tcattctttg cacgtaaatt ataagcaaat tgaagaaaaa cttatgttga aatgaagaac
     1921 aaatttgaga accgtagcga cactcgctgc ggttcttttt tatatatttt atatgaagta
     1981 ttctttattc c
//
LOCUS       DACDAF010000175         1954 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.184, whole genome shotgun sequence.
ACCESSION   DACDAF010000175 DACDAF010000000
VERSION     DACDAF010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1954)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1954)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1954
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.184"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            156..1862
                     /locus_tag="IVZ69_002757"
     CDS             156..1862
                     /locus_tag="IVZ69_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin/fibrinogen-binding protein"
                     /protein_id="HAP8184769.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT          699 a          387 c          353 g          515 t
ORIGIN      
        1 acctaaaaat ttggatttca acgatagaaa cactgttttt tatgtaatta gtccaagatt
       61 tttctagact tttgctttac tattcggcca aattggtttt tcttcttttt ttcgttataa
      121 tgaatatact tatgaaaaga aatgaggaat gaaccatgtc ctttgatggt gtatttaccc
      181 acgcgatggt caacgaattg cgtgaaacgt tactatctgg ccggatctcg aaaatccatc
      241 agccttatga aaatgaaatc gtgctggtga ttcgttcacg cggcaaaaac catcgattat
      301 tattatctgc gcacccaagt tatgctcgtg tacagattac ccaaatcgat tatcagaatc
      361 ctgataatcc gcctaacttc gtgatgatgc ttcgaaaata tttggatggc gctattttag
      421 aagacatcga acaaatcgaa aatgatcgag tgatccattt ccactttgct aaacgaaacg
      481 agttgggtga tctacaaaat atcatattga tcgttgaatt aatgggacgt catagtacga
      541 tcgtcttagt taatcgagaa actggaaaaa tactggatgc gatcaaacac attggaagct
      601 ctcaaaacac ttatcgttct ttgcttcctg gtgtagaata tgttgctccg ccaaaacaag
      661 aggtcttgaa cccatttagc tccgagaaag aaaaaatctt tcagcggctt tcccaaactg
      721 aactagatcc aaaagcaatc caacgtcagt ttcagggaat cggtttcgat atcgctcaag
      781 agctgaccaa aagattactg gaacgtccta atgaaaagat ggttgtatgg gacgaatttt
      841 tctcagccat cagccatcag cctattccta ctttttacga aacggaaaat aaagattttt
      901 tcacaccgat tgcttatcag gtattgtccg aacaggcatc tgctgtaaca gcttatccaa
      961 cactcagtca attattagat agctattatc acgaaaaagc agagaaagat cgggcaaaac
     1021 aacaaggcgg agaactgatt cgaaaaatcg aaaatgaact aaaacgaaat aaaaataaat
     1081 tgaaaaaacg tgaacaaaca ctcaaagaat ccgaaaacgc tgagaattac cgtagaaatg
     1141 gcgaactact tactactttt ctgacacaag taccacgcgg cgcaaaagaa gttgttttac
     1201 ctaattatta tgaagaagat cggccaatca aaatagcact agatccggca ttgacaccaa
     1261 atcaaaatgc acagaaatat ttccatcgat accaaaagct gaagaacgct gttaagctga
     1321 ttggcgaaca aatccaagaa gccaaagatg aaatccaata tcttgaatct gtcttatctc
     1381 aactggaaat tgccggccca atggatatcg aagcaattaa agaagaattg acttcagaag
     1441 gatacctgaa aaagaagaac ttaaaaaaac aaaaacgtaa gaaaccatct cagcctgatc
     1501 aatacttttc ttctgacgga acgctcattc ttgttggtaa aaacaatctt caaaatgacc
     1561 agctgacaat gaagacagct aaaaaaaccg actattggct tcatgcaaaa aatatacccg
     1621 gttcgcacgt catcattaaa agtgacaagc cctcagatga aacaattaca gaagctgccg
     1681 agttagctgc ctatttttca aaataccgat actctgccca agtgccggtt gatcttgtac
     1741 aggtaaagca tatccgaaaa ccaaatggcg ccaagcctgg ttatgttatt tatgaaaacc
     1801 aaaagacgat tatcgtgaca ccagaagaag aaaaaattac agctatgaaa caaaacaggt
     1861 aatcaatgag tgtttctaga atcatatttg cgtactttcc cacaacagca attagttata
     1921 aattgtttgc tacaaaaaga ggagttgtga caaa
//
LOCUS       DACDAF010000176         1881 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.185, whole genome shotgun sequence.
ACCESSION   DACDAF010000176 DACDAF010000000
VERSION     DACDAF010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1881
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.185"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            274..870
                     /locus_tag="IVZ69_002758"
     CDS             274..870
                     /locus_tag="IVZ69_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP8184770.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(928..1410)
                     /locus_tag="IVZ69_002759"
     CDS             complement(928..1410)
                     /locus_tag="IVZ69_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184771.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(1516..1713)
                     /locus_tag="IVZ69_002760"
     CDS             complement(1516..1713)
                     /locus_tag="IVZ69_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184772.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
BASE COUNT          641 a          368 c          284 g          588 t
ORIGIN      
        1 tttttaatgg caatatcata aaaaaaagaa gatagagatt taataattat atatcagctg
       61 tttttttcaa ataagcaaaa attcctaaaa cacaacaatg aaagcgataa ctaagaaaat
      121 ccttacataa cgatttttct tattaaaatt gttttttgaa cttcgcttat tttttgtgag
      181 catatctgtt tacttacttt ttgtaaggtg ctatacttca tttcgtaatc aattaaaaaa
      241 atgcaaaacg caaatcaaag gagaaatttt attatgacaa cttttactga cactttgaaa
      301 aaccgccgtt caatctatca tctaggacgt aatgtttcac tttctaatga agaattaaca
      361 actttgatca aagaagcaat taaagaaagc ccaactgctt tcaatgctca atcaacacgc
      421 gcagttatcc ttttcggaga tgcacatgaa aaactttggg aaatcactga agaagcactt
      481 cgcccattga ctccagcaga agctttccca aatacacaaa acaaattagc tggtttcaaa
      541 aatggttatg gtacagtatt attcttcaaa gatactgacg tggtaaaagg tctacaagaa
      601 caatttgaat tatatgcaga caacttccca gattggtcag aacaatcaaa cggaatcgca
      661 acagctaata cttgggtagc attagttgat aaaggattgg gcgcaaactt gcaacattac
      721 aacccagtta ttgacgaagc agttgcaaaa gaatggaata tcccttcaaa ctggaaacta
      781 cgttcgcaat tagtattcgg ttcaccagaa acaccggctg gggaaaaaga atacatgaac
      841 gatgccgatc gcttccgcgt atttggataa ttttatttga aataaaaaac agaggttgtg
      901 acaaacatct tgtcgcaacc tctgttttta ttctggatca atcataatat caatctctgc
      961 ctcatcgttt aagcgttggg acaaaaatgg aactaattct tctaatgatg cagaaaattt
     1021 cagcatcggt cctcgccatc cgtttcggaa aaaattcatt tttacgattt tagaaccttt
     1081 tggctgatat aatacaattt tattgatctc agaaaaagga acaccttttt tgtcaaagct
     1141 attcaaaaca agtccttctt ctgtgattcc tctactgtcc aacaaaaaac taataaaaat
     1201 cattgctgac aagatccctt ttgccaattc atctgctgta ggatgactga tgagtgtata
     1261 ccaaatgact agtgacacta agaagggtat caccaagtag acccatcgat ttcgcacagt
     1321 ccgataaata atttcttttc gaaccagcca aagaaataaa aacatcacaa caacgaataa
     1381 aaacaataga accgtaaaga atgttaccat gacaactcgc ctcgcttttt cttctccaga
     1441 aaataggaaa agaatactga tttaccttct caaagaaatt ggacttgcag cacgccgcac
     1501 gtccaattgt tttctttatt caaatgtatc atattttgca acaaccatgc ttgctttttc
     1561 atctaataat tcttggtcct ctgcagcaca ttgggcaact ttgaccacgg cgcagtttgt
     1621 catttttgat acaacttcac caatgaccgt ttttgtaaaa ccaattggtt tgcatgcata
     1681 ttgttctcct aaattaatca tttcttccgt catcaaaatc ctcctaaact gctggaactt
     1741 ttctccacat taccactgct atttctttgg agatttaact cattgatttt tatttacagt
     1801 taaaaatcaa ccttacaggc attatagcgt actgttttcg ttttcacaat taaaacagct
     1861 gttgtattta gaagaatttt t
//
LOCUS       DACDAF010000177         1763 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.186, whole genome shotgun sequence.
ACCESSION   DACDAF010000177 DACDAF010000000
VERSION     DACDAF010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.186"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..722)
                     /locus_tag="IVZ69_002761"
     CDS             complement(<1..722)
                     /locus_tag="IVZ69_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HAP8184773.1"
                     /translation="MTYKNIVFDLDDTLYDHQLPFKRSVEKCFPTIDIQQIDNIYKRF
                     RCWSDVAFPKYTKKLISIEQLRIFRCQKTMEEFGIDSISRTEALDFQADYEYELDQIT
                     MIPEIHQLLLALHKNRIPIGILTNGPVDLQSRKLQNIGAYQYFEKQNIIISQSTHGGA
                     AENSYEGNVKNLQSYQNVQLSKRAIEILKEEIELNHQHIRFNPDYKDNGWIFTSKSRH
                     KPGMATVFLTNFIRCRTSFRML"
     gene            complement(727..1494)
                     /locus_tag="IVZ69_002762"
     CDS             complement(727..1494)
                     /locus_tag="IVZ69_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HAP8184774.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
BASE COUNT          553 a          284 c          300 g          626 t
ORIGIN      
        1 aatagcatac ggaaagaagt tctgcacctt ataaaatttg tcaaaaaaac tgttgccatt
       61 ccaggtttat gacgactttt ggaagtaaaa atccatccat tatctttata atcaggattg
      121 aatcttatat gttggtgatt taactcaatt tcctctttaa gaatttctat agccctttta
      181 gataattgga cattttggta actttgtaag ttttttacat taccttcata gctattttct
      241 gcagctcctc cgtgagtgga ctgactaatg atgatatttt gcttttcaaa atattgatag
      301 gcaccaatat tttggagttt tcgactctgt aagtcaacag ggccattagt tagaatacct
      361 attgggatgc ggtttttatg tagagccagc agtagttgat gtatctcagg aatcatcgta
      421 atctgatcga gttcatattc atagtcagct tggaagtcta gagcttctgt cctagaaata
      481 ctatcgatgc caaattcttc catagtcttc tgacagcgaa aaattctaag ctgctcaata
      541 ctgatgagtt ttttcgtgta tttaggaaaa gcaacatcag accaacatct gaaacgtttg
      601 taaatgttat ctatttgttg gatatcaatc gttggaaaac atttctcaac gctacgttta
      661 aaggggagtt gatggtcata aagagtgtca tcaaggtcaa aaacaatatt tttataagtc
      721 ataattctag tccgctttta aaatagtagt gtactggcta aattcctcta agtgttgagg
      781 gctaatctgg ttatctgtaa tgatggtatc gagttgatct agattataga agttaaagaa
      841 atcgtatcga tcgaatttag tactgtctac taataagaat ttttctacag cattgtttag
      901 ggcaagttgt tgaatcacac cttccttgtc actatatgta gcaatagaat tatgggtaac
      961 agcatttgca ctaacaaaag ctttggcaaa tctaattgct tttaaatttg tcgaagccat
     1021 tgaacctaca aaagctccag ttatttctct atattcaccg ccaagaagca ataaatcaat
     1081 ggtttcgcta tcatttagaa tcaagaacac agggagacta tttgtaatga cacgaatttt
     1141 ataaccttta cgacctttca attctaatgc cagttgttca agtgtagttc cgggtccaat
     1201 aaaaatagta tcgccatctt tgattaaaga gcaggctttt ttagcaatgt caattttttc
     1261 ttttgtattt agacttttct tctcgatatg tgtcttttca agtggctttt tagaggaaag
     1321 taattgtgca ccaccatgag tacgtgttaa aagtccatca gcttctagag catcaaggtc
     1381 tctacgggct gtcatatcgg aaatatctag ttcatctatt atttctttta tggttatggt
     1441 cccatcaatc tttaacatat ctaaaatttt ttctaatcgt cgttttttgt tcatatgaag
     1501 acccttcttt cataaagtaa tttttttcca aagataattc tcttttaatt gtatcataaa
     1561 agacaatatt ttcaaggtaa aacaaacaat ttcaaacaaa aacaaatgtt agatgatgaa
     1621 ataagaacag tggattgacg tatattagct taggtcagat tttgtataag acgaaaataa
     1681 agtaggacct cttaatcagt aagttataga aagtaaaaga cttttgtaat acttgaatag
     1741 atatttcacg tccattttgt gat
//
LOCUS       DACDAF010000178         1665 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.188, whole genome shotgun sequence.
ACCESSION   DACDAF010000178 DACDAF010000000
VERSION     DACDAF010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1665)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1665)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1665
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.188"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            132..506
                     /locus_tag="IVZ69_002763"
     CDS             132..506
                     /locus_tag="IVZ69_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HAP8184775.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(620..1249)
                     /locus_tag="IVZ69_002764"
     CDS             complement(620..1249)
                     /locus_tag="IVZ69_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HAP8184776.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1383..1455)
                     /locus_tag="IVZ69_002765"
     tRNA            complement(1383..1455)
                     /locus_tag="IVZ69_002765"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1420..1422),aa:Thr,seq:ggt)
BASE COUNT          584 a          240 c          283 g          558 t
ORIGIN      
        1 tctacactct gagatgtaag aaatatcata agatatttct tacatctttt tgttttgagc
       61 aggactttag ataattttat taatatatgc tagcatgctt ttgtaagaaa aagaaagagg
      121 gcgtattagt tatgtatctt aaaattacgg aacaagcaca agaaagatta caaaaatata
      181 ttgatgaagg cgcaacagtt atattggatt tagatgatgg cgttggggaa tattctaaaa
      241 tgggtgtttg ctctttagat actagttttc gtttacttct tcttgataaa gaacagagaa
      301 aaaatgatta taaactccaa ttagatagtg atattgggga tgtttatata aaagattatt
      361 caaaaatgta catggatgaa catatgaccc tttctttaga tccacgtcta ggtgtattta
      421 ctcttgaaag cccaagtggt tctttagaca gtcatgttca attagtagat ctacgaccag
      481 aaaaattctc tggaataaaa caataacttt ctctctattg tccataaaac tagtctcaat
      541 caagctgtat tgaaaaaaca agacaacatt cttaccatgg taaataaaaa gacgacacat
      601 tttgtcgtct ttttttaaat taactatttt cgataaaaga tcgcatagct tgtgccatta
      661 tttctggctt ttctctattc aattcatgtt ttccgttttt aataaagagt agccggccat
      721 tcgttgaaag tttatataaa cgttttgctg ctggtttatt cgcatgatct ttggtaccgc
      781 ataaaatcaa tttaggaagt cgtgatgtac gaagctgttt tttgcagtct aatgtttcaa
      841 gtgaacgaag tagggtaagg gtttgttttt tagatagacc taatttttca aatatcttag
      901 aaggtacgca gtaaaaataa atattctgga aagtaagcaa taagcgatta ggagactcaa
      961 attgtggagc gactaaaaca acctttttta aatatggaga aggagttgca agatagttta
     1021 aagcaataac agcgcctaaa gataatccac ataaaataaa aggttccttt atctgattca
     1081 attgtacttc gatgtatttg gttaagtcgt ctaaagtagc agtgtctgtg ctgtttaaat
     1141 gattgaacaa tgaaagactt ttgcaagaat aactattggg tagataagag attacatctt
     1201 tccatgattg ttcgtcttgg cctagaccat gcaaaaaaac aattttcata ttgctctcct
     1261 ttttatagtt atcatataga ctttctttgt actattaaaa tataaacatt catttcttac
     1321 gtcataaaat aaaaaaacag cgcagacaca ttgttaaacc aacatgttgc actgtttaag
     1381 gaagccactt gccgggcttg aaccggcgac ctcttcctta ccatggaagc gctctaccag
     1441 ctgagctaaa gcggcattat cattaataca aataatagga taacgaatat taatgtattt
     1501 gtcaacagaa ttttttcgaa aaaatgtgtt tctctaatag gaaaacagat tttagaaaaa
     1561 ataaaaataa caaaaaatgc gaacggtttc tttgataata taataaaaaa attcaaaaaa
     1621 agtattgcgt tatttagaag aaattgatat tatattcatg tactt
//
LOCUS       DACDAF010000179         1657 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.189, whole genome shotgun sequence.
ACCESSION   DACDAF010000179 DACDAF010000000
VERSION     DACDAF010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1657)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1657)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1657
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.189"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(101..586)
                     /gene="vanZ"
                     /locus_tag="IVZ69_002766"
     CDS             complement(101..586)
                     /gene="vanZ"
                     /locus_tag="IVZ69_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAP8184777.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
     gene            complement(739..1650)
                     /locus_tag="IVZ69_002767"
     CDS             complement(739..1650)
                     /locus_tag="IVZ69_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAP8184778.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
BASE COUNT          532 a          317 c          224 g          584 t
ORIGIN      
        1 acacctacgg gcgagtttcc ccacatcccg ttttccatct aatccaattc attcaatatc
       61 tttatgtgta tgaaagatca gattgcttga tttagacatc ttacacgtaa tttattctta
      121 aatgggtacg gtaaacgagc aataatacga gcaaaagtat acctacaaaa ataataactc
      181 tgtctaattt tttttgattc atatgcttat tgcttaaacc atataatttc agtccaagaa
      241 agcctccaac agtatttgta attacatctg ttatgtctgt cgctccaata gcgaagataa
      301 attgaattat ttcaaaagta agacttaaaa ccagtacaaa agcaaactta ggtaaaaatc
      361 cgatttcttt aaaattgaca ttcaaaagca agccaaatgg aataaagatt ataacattat
      421 ctatcatctc tctgaaattc ccagtagcag taaatggagt caagttaaga cttctttgat
      481 gataattaaa tactgataaa atattgtatt gtaatttgaa taacactaac cagattagtg
      541 tcactaaata taaagctagc aatcctctag ataatatttt tcccaatata atttcctcta
      601 attcttttgt ttaagttgta tcattagtat agcaatgtcc tagttaacgt gggttttaaa
      661 ttaaaaagct aacgttaccc caaaagtgct agtacaataa tgctgttcat taatttcgtt
      721 ggtttcattc cgccatcctt acctccttga attagtatgt gttgatccgg gaaacactgt
      781 cacaattaca ccgtctatat tgtttcctga tatctcataa cgaagattag tcggcacatg
      841 aatggtggta tttttagtaa caggataata aaagatctca tatttttccc catttacact
      901 aacagaaatg gttttttctt cttttaggta atccatatat tcctcgagaa cgaaattctt
      961 ttctttcata atcgcactat gtggtaaacc aacatagcga atatgccatg gttcatattg
     1021 aattcctgtt aactctgttt tgtcctctgg ataacgtaaa atgaacccgt atttccaagc
     1081 attttcttct atccactttc cttcaggggc tcgttccatt ttcgtcaagc ttgatcctac
     1141 atctagtgat aaacctgaat tatgctcact ataacctgct ggtaaggcat actcagcccc
     1201 catttcttgg taaagcacac tttgctcatc aaagtctcga tagccactat taataataaa
     1261 atgactaacg ccacccttta cagcatcatt gaccatctct gaaaattttt gtgctatttc
     1321 ttttgacata taaatattac tatcaagcaa cccgtatcca tttattaatt cgtcatgttt
     1381 agataaattc acgatatctg acttcacact ttcttggcga acaggatatt tactattgat
     1441 taatagcaga tttccttgat aaacctgttc ttctgtaatt gttttctctt gggtattttc
     1501 agaagtccca ctattttcta aatgttcttt gggattttga tcataatttt gaaattcgac
     1561 tttttcctga gaaaacagtg cttcattaac gtagtcataa cctaagtata ttaagaataa
     1621 caataacaat aaaaaaaaca acttcttcat tttcagt
//
LOCUS       DACDAF010000180         1621 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.190, whole genome shotgun sequence.
ACCESSION   DACDAF010000180 DACDAF010000000
VERSION     DACDAF010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1621)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1621)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1621
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.190"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            16..276
                     /locus_tag="IVZ69_002768"
     CDS             16..276
                     /locus_tag="IVZ69_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184779.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVIGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(638..877)
                     /locus_tag="IVZ69_002769"
     CDS             complement(638..877)
                     /locus_tag="IVZ69_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184780.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            1163..1477
                     /locus_tag="IVZ69_002770"
     CDS             1163..1477
                     /locus_tag="IVZ69_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184781.1"
                     /translation="MDFYSNFILIIAILLLLNIWFFDKSRNAGIGFRTKRSTSSEKKW
                     VYSQTIFYGGVISISLLSSTLYSFNVIDVSMSNFISIIGILISAIITQLLLVFEEKSK
                     NN"
BASE COUNT          558 a          219 c          286 g          558 t
ORIGIN      
        1 aaggatggat gaaatatgaa taacgaaact atcattttag gaaaaaaata tatttgccaa
       61 cctattggct tgaaacaaaa agtgattgga gaagtaatca gtaaattaga aaattgtgtt
      121 gtgatctgcg tagacgaata tcatgacgtc gatcgcaatg aaatattaga aaaatgcgga
      181 aaagtagtgg caaaatatac tcacgtttat gagttggaaa caacagaata tctatataac
      241 tatagcaaca aatatgaaca tactttagtt tcataaagat ttaaataaag tgccttcaaa
      301 agcgagaaga ccaagctttt gaaggcactt tatttagttg gcagtgattg ttcatgattt
      361 ttgatttatt caaaaggttc gcctagagaa tctgtctctg taacgaggcc tggtggagaa
      421 actcgataaa aacctatact gccagaactg tcctattttc ggatagacaa actagtagtt
      481 ttaaaaagat catccgatcc aatcatttca aaaaatgcaa aactgatatc aggatcattt
      541 agctcaggct tgttatcgta aagcatttgt aaaggttgca tttagttagg agtaaacgcg
      601 aaactatcat cattatttgc tgaagaagat gaagaagcta attcagagtt tgtttgaaat
      661 aaaggagacg tgctgacagt ttctttaccc tgttttttgc agaggtagaa acttttatat
      721 cggaagtttc taccggagaa tttttctcat ttgtagaaat tgttgaatcg atactattcg
      781 aaatttgcgt atctgaaggt atgttctttg atgcagaagt cccacaagca gtaagtaaca
      841 ataaatttga taaactgata aacagaattc ttttcattat gtacacactc cttatagtat
      901 cgtttagcat acacctatgc tcagtattag gcaaaatcaa tgcaaaacta tcaagtcttt
      961 tatagtatct attagtctta gtaatacata tatggagagg gtgatatccc agttcaaacc
     1021 agatacattg gttaccatct gtattaacga ttatgcctct aaacgctttt tttatgaaaa
     1081 aatttataag tgaaaacgta ggtatgatat tatctagagg taattttttt gggtatttaa
     1141 atagttgcta ggaggatagc ttttggattt ttacagtaat tttatcttaa taatagcaat
     1201 attattactt ctaaatattt ggttttttga taagagtaga aatgcaggga taggttttag
     1261 aaccaaacga agtacgtctt ctgaaaaaaa gtgggtatat tcacagacta ttttttacgg
     1321 aggggttatt tcaatcagtt tactttcttc aacactttat tcttttaatg ttatagacgt
     1381 ttccatgtca aattttatat ctattattgg aatccttatt tctgcaatta ttacacaact
     1441 acttcttgtg tttgaagaga agtcaaaaaa taattaaagc aattatgcct tttagtacag
     1501 gaattattac ttcttacaaa tgtatagcga atgtgaagcc tgctgtttta attgttctag
     1561 aaaaactttt gagtgaacaa ttattttatg ttaggatgaa ttaatttctc tagagtttat
     1621 a
//
LOCUS       DACDAF010000181         1586 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.191, whole genome shotgun sequence.
ACCESSION   DACDAF010000181 DACDAF010000000
VERSION     DACDAF010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1586
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.191"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(305..604)
                     /locus_tag="IVZ69_002771"
     CDS             complement(305..604)
                     /locus_tag="IVZ69_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HAP8184782.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
     gene            955..>1586
                     /locus_tag="IVZ69_002772"
     CDS             955..>1586
                     /locus_tag="IVZ69_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HAP8184783.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
BASE COUNT          538 a          247 c          211 g          590 t
ORIGIN      
        1 tttttcgcat atattcattt tattttactt attgctttca ttttttcaat ctatatttcc
       61 aatttttaac ttacaaaaat gcaacattaa taaataacga tagtttcata aaatacactt
      121 ttaattaaca ttattagttt atactagctg tttttgtgtt aattaaagga taaaatacaa
      181 tataaagaaa catctgtttc tttatttaga ataaaaaaat acagactctg ttcaaataaa
      241 tgaacctagc ctgcattatg agattgacta tactttttaa ttcattgaga tgaataactc
      301 gtttttataa atgcccaaaa gtaatcggtg ccgaagccat tcctcgacct aattcttttt
      361 caaattttcc tattgttgat atctccatat aaaacggtga tactggttta gacaattctc
      421 ccctgattgc taacggacgt aaactacgtt ccaaattatt tatgacttta ggataatact
      481 gacctttttc taagcctgtc tttgcgtcta tcaaaagtat acgttccttt tctttgatct
      541 ctggatttaa aacgagatca tataatttta gtaccatgtt ttctatttct tcacttttag
      601 acatcacgat ttcctcccaa aaatatattt cttcccacta cattctataa acaaagtata
      661 cgctacatct agattttttt aaatcattac tggattgtta aaacctttca atacactgtt
      721 atggcaacga tttttatttt aaaaacattc taaattaaat cagtaaaaat ttttattcta
      781 agatttttat tagaattacg cctaatttgt gtctctcagg gcaattctaa gaacgtttca
      841 agagatagcg acactatcgt tatcgaaaaa ggcgaaaacc tatctcattt tctgctaatg
      901 taagttggtt tagcttttgt taatatgact ttatgaaaat ggaggtaatt aaatatgatt
      961 tttcctaaag ttaatgaagc aagcttgaat aaaggatcct tttttcatat ctatgaaaac
     1021 gaagattttg aactgtataa tatcctttca caaaaagagg tcatcgaaaa ccaaataatc
     1081 tgccatccaa ttatttacaa atctattttc aagtatgcat tttttgcttc caatgatttt
     1141 caaagaatgg agattaccga ctgtatattc gaaaactgtg atttttcagg ctgtatattg
     1201 acaaaaagca tgttgcatcg cgtgaaattt gtcaattgta aattaacagg tactaaattg
     1261 atggaaagtt atattgggaa cacgttattc gagaattgta aaatggacta tgtaaattta
     1321 tctggttcaa acataaaaga aagtaccttt gagcactctg tcttatcaag cgcagatttt
     1381 gtagactgtt ccctcactaa aataatgttt tctactaatg atttagaaaa tgctagcttt
     1441 tttgatactg atttaaaaaa tatcgattta agtagcaact cctttgaaat gattgaagta
     1501 cgctcggaac atctaaaaaa ttgtacgctt aatcagttgc aagcacttgg ttttgctaga
     1561 aaatttttac aaataaaagt agtata
//
LOCUS       DACDAF010000182         1573 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.192, whole genome shotgun sequence.
ACCESSION   DACDAF010000182 DACDAF010000000
VERSION     DACDAF010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1573
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.192"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            45..104
                     /gene="ermCL"
                     /locus_tag="IVZ69_002773"
     CDS             45..104
                     /gene="ermCL"
                     /locus_tag="IVZ69_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HAP8184784.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            164..898
                     /locus_tag="IVZ69_002774"
     CDS             164..898
                     /locus_tag="IVZ69_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HAP8184785.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          589 a          248 c          211 g          525 t
ORIGIN      
        1 ttgtgctata attattctaa tttcataaaa aggagaatta atatatgggc atttttagta
       61 tttttgtaat caacacagtt cattatcaac caaacaaaaa ataagtggtt ataatggatt
      121 gttaatataa acattcatta taacctcata ggagtgggtt ataatgaaca aaaaaaatat
      181 aaaagatagt caaaacttta ttacttcaaa gcatcatata aatgaaattt tgagaaatgt
      241 acatttaaat acaaatgata atattattga gattggttca gggaaaggtc atttcacgtt
      301 tgaattagct aaaaggtgta attatgtaac cgccattgaa atagatccta aattatgtag
      361 gataactaaa aacaaactta ttgaatatga gaacttccag gttatcaata aagatatttt
      421 acaatttaag tttcctaaaa ataagtcata taagatatat ggaaatatac cctacaatat
      481 aagtacagat ataattcgaa aaattgtttt tgaaagcaca gctacagaaa gttatttaat
      541 agtggaatat ggatttgcta aaaggttgct aaatacaaat cgttcactag cactattttt
      601 aatgacagaa gttgatatat ccatattaag taaaatccct agagaatact ttcatccaaa
      661 acctagagtt aatagctcgt taattgtatt aaaaagacac ccttcaaaaa tatcactcaa
      721 agatagaaaa caatatgaaa attttgttat gaaatgggtt aacaaagaat acataaaact
      781 attttccaaa aaccaatttt atcaagcctt aaaatatgca agaattgacg atttaaacaa
      841 tattagcttt gaacaattct tgtctctttt caatagctat aaattattta atagataagt
      901 taaggggtgc ataaactgca tcccttaact tatcttattt tgcttaaaca atcttggccc
      961 gtaaactgca taactcatat gtaaatcgct cctttttagg tggcacaaat gtgaggcatt
     1021 ttcactattt ccggcaatta cttccatgta aagtataacc cactatactt tgcaagcaaa
     1081 gtgtgggctc gccgaggggt cttgcagacg gctctttcgg ctcttttgag ccgagtatca
     1141 gcgcaccctt atggtgcaat tagctgatac ctgtttgacg atttgctgcc ctaccttttc
     1201 ggtaggtatg caaacctcaa accaaaataa aaaccccctt cgacttcgtc agggggtttt
     1261 tatttatata aatctccgta aataatcgcg atttaataac atcttcaatt ttattttttt
     1321 gcgtatttta gaaatgtttt cactaaaaaa tatattatac aaaaaataca gtaatcgatt
     1381 ataattcttt gccagttaaa tatcatatcg ttattaaaat atcggaaaaa aatatcaaca
     1441 acaataaatg caaaagaaga ccataaaaat tgtttattac tcatacatac tctccatttc
     1501 tatcattttt aaatttacca gtcatctctc aaaaatctcc tagctatttt tcttttttaa
     1561 ccacataccg tca
//
LOCUS       DACDAF010000183         1541 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.193, whole genome shotgun sequence.
ACCESSION   DACDAF010000183 DACDAF010000000
VERSION     DACDAF010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1541)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1541)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1541
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.193"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            25..1491
                     /locus_tag="IVZ69_002775"
     CDS             25..1491
                     /locus_tag="IVZ69_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HAP8184786.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
BASE COUNT          423 a          289 c          326 g          503 t
ORIGIN      
        1 atttaaagaa ttggggtata gattatggaa aaacagcaag acaagggctt cttcgggcag
       61 ccgaagggat tgtcaacttt gttcttcact gagatgtggg aacgatttag ttattacggt
      121 atgcgtgcat tacttatcta ttatatgtac gatacagttg ccaacggggg acttggatta
      181 ccacgagcaa cagcattagc tatcatgtcg atctacggat ctttgatcta catgtctagt
      241 atcgtcggcg gatgggtatc tgaccgagtg ttaggagcaa aacgcactgt attcttcggt
      301 ggagttttca ttatgcttgg ccacatcgtc ttggctttac catttggtgt aagtacattg
      361 tttgtttcga tggcattgat tattatcgga accgcctttt tgaaaccaaa tgtttctggc
      421 atggtcggac atctttattc aaagactgac ttgcgaagag atgcaggatt ttcgattttt
      481 tacatgggtg tcaacttagg ggcattatta gcaccactaa tcgttggtac aatcggtcaa
      541 gaatataact atcatttagg gttctcttta gctgctattg ggatgttctt tggattatta
      601 caatacatca tccaaggacg caagacatta gacggagtgg gtacaacacc gccgaatcct
      661 ttgacaactg aagaacgtaa aggattcatc cgtaacttga tcatcgcact tgttgttatc
      721 gctgcagtat tcggcggggc acaactaact ggtcatctga caattgactt ttttgtcaat
      781 acaatcagtg tattggggat tatcttaccg ttgtattact ttatcaaaat gctgacttca
      841 aaagatgtaa ctgctgaaga aaaaccaaga gtatgggctt atatcccatt attccttgca
      901 gcaatcattt tctggtcatt acaagaacaa ggttcatcta tcttagcttt atttgctagt
      961 gaacgtacac aatctacgct atttggtgta acgatccaag caagctggta tcaatcattg
     1021 aatccaattt tcatctttat tctgacacca gtattcgtaa cgatgtggac gaaacttggt
     1081 gaacgtcaac catctacagt agtgaaattc tctcttggac ttttatttgc aggattatcg
     1141 tacttgctat tgatgttgcc gggtatgctt tatggtacaa gtggaaaagt aagtccattg
     1201 tggttgttgg gaagtttctt catcgtggtt attgctgaat tgtgtctttc accagttggt
     1261 ttgtctgtga caacaaaatt agcaccacga gcatttgaat cacaaacaat cgctatttgg
     1321 ttcttagctg atgcttcttc acaagcaatc aatgcacaaa ttgcacgctt ctacacaccg
     1381 ggaacagaat ctgcttactt cggtattatc ggtgcagtag caatcgtcgg tggtatcttg
     1441 ctatttactg tgaaagaacc aatcaaaaaa ctaatgggct ctattcatta atcaatgaac
     1501 ataaaaacag gaattgctta tttgcagcag ttcctgtttt t
//
LOCUS       DACDAF010000184         1531 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.194, whole genome shotgun sequence.
ACCESSION   DACDAF010000184 DACDAF010000000
VERSION     DACDAF010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.194"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..1343
                     /locus_tag="IVZ69_002776"
     rRNA            <1..1343
                     /locus_tag="IVZ69_002776"
                     /product="23S ribosomal RNA"
     gene            1437..>1531
                     /gene="rrf"
                     /locus_tag="IVZ69_002777"
     rRNA            1437..>1531
                     /gene="rrf"
                     /locus_tag="IVZ69_002777"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          428 a          329 c          449 g          325 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa gtacagtgat gtatggagcg gactgatact
     1321 aatcgatcga ggacttaacc aataggttaa aagaaaagaa ctcggaaaaa aacttatgtg
     1381 acttcaaatc cagttttgag tgaacaaaat ttactcaata aaagataaca ccacagtgtg
     1441 gtggcgatag cgagaaggat acacctgtaa ccatgccgaa cacagaagtt aagcttctta
     1501 gcgccgattg tagtgagggg ttgccccttg t
//
LOCUS       DACDAF010000185         1469 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.195, whole genome shotgun sequence.
ACCESSION   DACDAF010000185 DACDAF010000000
VERSION     DACDAF010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.195"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            84..494
                     /locus_tag="IVZ69_002778"
     CDS             84..494
                     /locus_tag="IVZ69_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HAP8184787.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            508..864
                     /locus_tag="IVZ69_002779"
     CDS             508..864
                     /locus_tag="IVZ69_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HAP8184788.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT          540 a          211 c          271 g          447 t
ORIGIN      
        1 ttttttatat tttattagct aataattggt attttaaaag aaattactgt agaattggat
       61 tataattaaa aaggagtgag aaaatgataa aagtatatac ttcgcctagc tgtacttcct
      121 gtagaaaagc aagagcatgg ttgcaagcga atcaacttga atttgaagag aagaatattt
      181 ttgccgaacc gttaacagaa agtgagatca aaaagatctt ggcagcgact gaaggaggag
      241 ttcaagatat tatttccact cggtcgaaaa tttacgaaaa gctgggcata gattttaacg
      301 aattaacttt aaagcaaatg atcgtcttat tcaaagaata tccttcatta ttgagacgac
      361 ctattttgat tgatgaaaaa agaatactaa tcggatttaa tgaagatgag atccggtcat
      421 ttgtccctcg tgaaattcga tgtgttgcca gaaatctgat ctatttacaa aacaataaca
      481 tcttaaattc atagggaggg agccttcgtg gaagtgaaag tctatggatc agcgcactgt
      541 gtaacaagtc tgaaggcgaa acaatggtta gaacaccatc aattgcctta tcaatttgtt
      601 gacttagaag aacgcgatct aagtacagaa gaagcagaag aattatgcag ttttgaagaa
      661 gtgcaagcag aacagctatt tgcgacttgg tctgaggctt ttcacaacat tgcgattgac
      721 ctttcctgtg taggaaaaaa acaactgatt tttttatgca cacaacatac caatctcctc
      781 agacgtcctt tgattattat cgatgaagtt ctatttattg gatacaatga gcagttgatg
      841 gaacagctta tcttaaataa atagacttta actgttttaa tcaagtcact gagcatttca
      901 tacagttgta acagtcgaac acttagcatc aagcgtgtta tgtgttcttt ttttgacttt
      961 atttttctac tatagagaca tgctcaattt atgtggtcaa aattcaaatc taggtgggga
     1021 tatagagtta aaaatatatt gacatgtgta aatttacatg atatattcat ttctgttgtt
     1081 ttaagtagca aagcaataaa atagtatttt aaaaaacata taaaatagtt gttgacatgt
     1141 tagaaatgac atgataagat aactgagttg ttaaaaaaga accacttgtg aagcttgatt
     1201 ctatcgaaaa aaacttcaaa aaagttcttg acaaataaca aatgataagt tatgataaat
     1261 gagttgctgt aagatttcga aaaacgaaat caaaaaaact tttaaaaaag agttgacaat
     1321 tacttgtctc tctgatatga tataaaagtt gctacggcag ccaaaaacga atcggggaac
     1381 actcctgatg aagtagacct ttgaaaactg aacaaagtaa gacaaaccaa atgtgtaggg
     1441 cgtcttgatt caattcaaga caacaaaca
//
LOCUS       DACDAF010000186         1466 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.196, whole genome shotgun sequence.
ACCESSION   DACDAF010000186 DACDAF010000000
VERSION     DACDAF010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1466
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.196"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(1014..1304)
                     /locus_tag="IVZ69_002780"
     CDS             complement(1014..1304)
                     /locus_tag="IVZ69_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184789.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT          469 a          288 c          205 g          504 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tataga
//
LOCUS       DACDAF010000187         1461 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.197, whole genome shotgun sequence.
ACCESSION   DACDAF010000187 DACDAF010000000
VERSION     DACDAF010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1461
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.197"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..1359
                     /locus_tag="IVZ69_002781"
     CDS             <1..1359
                     /locus_tag="IVZ69_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HAP8184790.1"
                     /translation="LFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLPITEKE
                     HLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEKEGLSS
                     FKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRDNITNW
                     HIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKDSQHPI
                     VYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFFEAIPK
                     GKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWMATIDP
                     VAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHSTSLEG
                     ARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDVQQHFS
                     RN"
BASE COUNT          481 a          266 c          308 g          406 t
ORIGIN      
        1 ctttttagtg atgaagaaat ttctgtaagt gttccagaag cagctgccac cattattcca
       61 gtaaaaggac atcaacgagt tgtaggaacg aaagcagaca aaatcaaaca cttacctata
      121 acagagaaag aacatctcct tcctttggaa gaacaatttt gtgaacattg cggttcacag
      181 atgaaagata tcggacggac aaaagtacga gaagaaattc gtttccatca ggctatgttg
      241 gattgtctca cccattatca acatacctat tgttgtaaaa gctgcgaaaa agaaggactt
      301 tcttctttta aaaaagcgat cgttcctaaa cctttgattt ctaatagctt aggttccaat
      361 agtttagtgg cggaaacgat ccggatgaaa tttggtcaga aagttcctgc ctatcggcaa
      421 gagaactatt ggaaacaaac acatgggttg gatatttcga gagataatat caccaattgg
      481 catattaaag cagtgcaaaa cgcgttagac cctttaggag aacgattaag agtctatctt
      541 aatcaagaag agattctaca cggggatgaa acaagttatc gtgtgattga aagtgccaaa
      601 acagatacct attactggca gttttgtaca ggaaaagaca gtcagcatcc catcgtttat
      661 tatcaccacg acgaaagtcg tgctggagat gttccgaaaa cttttctcaa ggagtttaca
      721 gggtatttac actgtgacgg ctatagcggg tataatgccg tggaaagtgt acgacttgtc
      781 tattgtttcg cgcatgttcg gcggaaattt ttcgaagcaa ttccaaaagg aaagaaaaac
      841 acggatattc ccgcagctca agcagtcaaa caattggata aatggtttgt cctagaaaag
      901 aaatggaaag acttttctcc tgagaagcga ttaagctgtc ggcaacaaga actgcgtcca
      961 ttatttattg ctttttatga gtggatggca acgatagatc ctgttgcaaa atccaagttg
     1021 gatgcagccg ttcaatatgc gtgtaaacta cgaagtggtt ttgaacctat ttttgaagat
     1081 ggtcgtttag aactcacaaa taatcgtgcg gagcgaaata tcaaagagct ggtgatagga
     1141 cggaaaaatt ggttgcattc cacaagtctt gaaggagcac gaacttcagg aatcattctg
     1201 agtgtatata aaacagcaga acttaacgga ttgaatcctg taaagtatct agagtttcta
     1261 tttgataaga taccaaatct tcccgtactt tcagcagaaa ctttagatca actgttgcct
     1321 tggaacaagg atgtacaaca acatttttct cgtaactaaa aacgccaaac attcccgatt
     1381 ctattctata ggtcgggtta tttgacgtac aggtactgtt ctatggggcg cttacttttc
     1441 ttcttcaaga ccaaataaaa a
//
LOCUS       DACDAF010000188         1455 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.198, whole genome shotgun sequence.
ACCESSION   DACDAF010000188 DACDAF010000000
VERSION     DACDAF010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1455
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.198"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            108..1040
                     /locus_tag="IVZ69_002782"
     CDS             108..1040
                     /locus_tag="IVZ69_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HAP8184791.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1112..>1455
                     /locus_tag="IVZ69_002783"
     CDS             1112..>1455
                     /locus_tag="IVZ69_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184792.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQ"
BASE COUNT          640 a          169 c          227 g          419 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caaga
//
LOCUS       DACDAF010000189         1432 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.199, whole genome shotgun sequence.
ACCESSION   DACDAF010000189 DACDAF010000000
VERSION     DACDAF010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1432)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1432)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1432
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.199"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..1217)
                     /locus_tag="IVZ69_002784"
     CDS             complement(<1..1217)
                     /locus_tag="IVZ69_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8184793.1"
                     /translation="MQTFLTKTSFKKVVLLDYLLEKDNWCAMEELRNLLNVTEKSVLH
                     YIEELEDLFKQYNGNILLKNEDNKRFFIKKEKDFPIYNIYLHFYKASYNYHLIDFMYK
                     YPRSVLKDFAKEQFTSVSTVFRYAKLLIPYFRRYHITFHPFQLELNASEANIRSFFYY
                     FYWNSTRESSDKWPFHIEQKEIEKYIVAFEGIYDITLTIFQKRVFSFWLAINIERSSF
                     RKVRVDNEYKSVISDDPHFNLLKKWSKQINLSFNSDELCFLYRIIYSFGVIDGNAIYE
                     NSHAYAHQRQNTCSYRAVENLEKVLQSMFRFSLDIKDPELIFNFIAFHERSYLFYGNP
                     DLFFNRSYIEEMKEEEPRTYHIMEKLKKELQANADLDVSKKLENWAQLFLDYYYVLDY
                     YDLFLTNVKPIKI"
BASE COUNT          518 a          224 c          166 g          524 t
ORIGIN      
        1 aaaatcttaa tcggtttaac atttgttaaa aataaatcat aataatctaa cacataataa
       61 taatccaaaa ataattgtgc ccagttttct aatttctttg atacatccaa atccgcattt
      121 gcttgtaatt cttttttgag tttttccatt atgtgataag ttcgaggttc ttcttctttc
      181 atttcttcga tatacgaacg attaaaaaaa agatctggat taccataaaa tagataactt
      241 ctttcatgaa atgcaataaa attgaatatg agttctggat cctttatatc taaagaaaaa
      301 cggaacatgc tttgtaaaac tttctccaaa ttctcaactg ctcgataaga acaagtattt
      361 tgtcgctgat gtgcatatgc atgactattt tcatatattg catttccatc aattactcca
      421 aaagaataaa ttattcgata aaggaaacac agttcatcgc tgttaaaaga aagattgatt
      481 tgttttgacc acttcttcaa aagattaaaa tgcggatcat ctgagataac tgatttatat
      541 tcattatcta ctcgtacttt tctaaatgaa cttctttcta tattaatggc taaccaaaaa
      601 gaaaatacac gtttttgaaa aatagttaac gtaatatcat aaatcccctc aaaagcaact
      661 atatacttct ctatttcctt ttgttcgata tgaaatggcc acttatcact actttcacgt
      721 gtagaattcc aatagaaata ataaaaaaag ctacgaatgt ttgcctctga tgcattcaat
      781 tctaactgaa atggatgaaa tgttatatga taacgcctaa aatatggaat taagagcttc
      841 gcatatctga aaacagtaga tacactagta aattgctctt tagcaaaatc ttttagaaca
      901 cttctaggat atttatacat aaaatcaatc aaatgataat tataagaagc tttataaaaa
      961 tgaagataaa tattataaat aggaaaatct ttctcttttt ttatgaaaaa tcgtttatta
     1021 tcttcatttt tcagaaggat attaccatta tattgcttaa ataaatcctc tagttcttct
     1081 atatagtgta agactgactt ctccgtaaca ttaagtaaat ttctaagttc ttccattgca
     1141 caccaattgt ctttttctaa caaataatct aataaaacta cttttttgaa agatgtttta
     1201 gttaaaaaag tttgcatcat ttcacctcaa taagttactt ttgtttattt taatcaaaga
     1261 ataaacttct ctcgttcgac tataactgat cgaacaaaag aagcctttta ataaatataa
     1321 tctcacttac atacataggc tagttatttg cttctagctt atgataagta tataaacgga
     1381 tatcgatttc ataattgttt tatcttaaac atcatagctg taattgtttt ta
//
LOCUS       DACDAF010000190         1426 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.200, whole genome shotgun sequence.
ACCESSION   DACDAF010000190 DACDAF010000000
VERSION     DACDAF010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1426)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1426)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1426
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.200"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..539
                     /locus_tag="IVZ69_002785"
     CDS             <1..539
                     /locus_tag="IVZ69_002785"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184794.1"
                     /translation="VMAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNG
                     QPMNDKRNGHSWFRQQERIENKVHSLREEIKQQEKQVEKLERQEEIKEMGYNKYGGLD
                     MTIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQA
                     IIDSGRVTQWKKIRPFIF"
     gene            566..>1426
                     /locus_tag="IVZ69_002786"
     CDS             566..>1426
                     /locus_tag="IVZ69_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184795.1"
                     /translation="MNENGEFEESKKYQATSEEEKAAVRELLEEAVPTDFLKEKENDH
                     FYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYYKFYFEEVKNGEVV
                     DQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKEQMQSKETKTKQKG
                     YQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFPERSFRNQLLIEEQ
                     FPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGFVREIEATPEDKKR
                     IESGQIEVIKK"
BASE COUNT          590 a          224 c          319 g          293 t
ORIGIN      
        1 cggtcatggc agaagaaaaa gaaccactag acaatagtcg tttgggaaaa tccaaaagaa
       61 aattagtacg attgcaaaat gaattaaacg aacaaattga aaagatgttt gaacaccaga
      121 gaaagaccaa cggtcaacca atgaacgata agagaaatgg gcattcttgg tttaggcaac
      181 aagagcgaat cgaaaataaa gtgcatagtc tgagagaaga gatcaagcaa caagaaaaac
      241 aagtagaaaa acttgaaaga caagaagaga taaaggaaat gggctataac aagtacggcg
      301 gactggatat gacgatcgag aatattccaa gaatcaaaga agaaatcgaa cgctttgaaa
      361 aaggtgaatc gactttttca gccgctacga tccgaaaata ccaacggaaa ttggaaacat
      421 tagaacagct gaaagaaaga tcggaaaaag gaaaagaaaa ccttcttcct gaagtacaag
      481 caatcattga cagcggacga gtgacgcaat ggaaaaaaat ccgaccattt attttctgaa
      541 aggctatcga aaagtcgctt tagaactgaa tgaaaacggg gaatttgagg aatctaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctgt
      661 accaactgat tttttgaagg agaaagaaaa cgatcatttt tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacgttgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaagaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccca tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcatactc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaagga ttttatgaga aaggacgtgg ctttgttcga gaaatagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaa
//
LOCUS       DACDAF010000191         1424 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.201, whole genome shotgun sequence.
ACCESSION   DACDAF010000191 DACDAF010000000
VERSION     DACDAF010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.201"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(150..1337)
                     /locus_tag="IVZ69_002787"
     CDS             complement(150..1337)
                     /locus_tag="IVZ69_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HAP8184796.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DACDAF010000192         1388 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.202, whole genome shotgun sequence.
ACCESSION   DACDAF010000192 DACDAF010000000
VERSION     DACDAF010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1388
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.202"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            154..417
                     /locus_tag="IVZ69_002788"
     CDS             154..417
                     /locus_tag="IVZ69_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HAP8184797.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDWKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            417..689
                     /locus_tag="IVZ69_002789"
     CDS             417..689
                     /locus_tag="IVZ69_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HAP8184798.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTHEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            766..1095
                     /locus_tag="IVZ69_002790"
     CDS             766..1095
                     /locus_tag="IVZ69_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP8184799.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1085..1371
                     /locus_tag="IVZ69_002791"
                     /pseudo
     CDS             1085..1371
                     /locus_tag="IVZ69_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
BASE COUNT          525 a          169 c          277 g          417 t
ORIGIN      
        1 ctctaggaaa aaattaacta gcaccacggg tataaaggaa acggataaca ctttacaatg
       61 ctgttttggt actccaattt aaacaaaaca atcgaattta cgtacttaat taagtacgtt
      121 agaatggaga tataaattag agggggagta gatatggcaa aaacagtctt aaatcctagc
      181 tcagcacgga aaaattttta taagttgttg aaagatgtaa atgagaatca tacggaaatt
      241 gaaatcatta gtgagcgcag tgaaaataat gcggtgctta ttggtttgga tgattggaaa
      301 gcaatcaaag aaacgctatt acttgagcaa ataggcactt tgggtgttgt tcgtaagcga
      361 gaaaaagatg atagtggatt tactaatgtt gatgaaattg attgggataa cttataatga
      421 ataactattc tgtgatgatt aaaaactcgg ctaaagctga tttaaagaaa atcaaacagt
      481 ctaatttgaa acctcaattt gagaaggtta ttcagacttt aaaggaagat ccctatctcc
      541 ctacccaatc atttgagaag ttaaaaccta cacatgaagg taggtattct agaagattga
      601 atagacaaca ccgggttgtt tataaggtag atgaagatga acacgtggtt gaaatttatt
      661 cagcaaggac gcattacgag tcacagtaat tacttgtaaa tacattatct cgtggtataa
      721 tgtatttact aagtaattac atactgttag aaatgaggga tttaaatgat tacaaaaaca
      781 agaaaacaag gcaattcaat catgttgaca gtacctaaag attttaatgt tcctaatgga
      841 gtcgaagttg aagcaaagtt ggtagagaat ggtattcttt atgaatttgt tgaaccacaa
      901 aaagaatttt atgattttag cgaagatatt ttgtctgata taattgcaga aggctacgat
      961 aaagatgaga ttcttgtaga atttaagaat agaaaaaaca aaatgcattc ttcctttaga
     1021 gatattgctg aagatacact tactaattct aaagtaatga ctaaagagga gttggcaaca
     1081 gaaattggct tatgaaatcg ttccttcaaa acatgtcatt aagtatttaa aaagctaaaa
     1141 gagaagccat tgaaagaaaa atttttgaat ttaatttatg atgaaattgc gattgatcca
     1201 tataagggtg aacaaaaaac tggggattta tcaggtattt ggtctagtgg gttcaaatat
     1261 gcgggcacaa catatagagt agcttacgag attatagaaa acaaggttat tccagtattg
     1321 ttatgtggaa cgcatgaaaa cttttatgaa cagttgaaaa aattaatcta gtgatttgtt
     1381 gtcgttct
//
LOCUS       DACDAF010000193         1361 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.203, whole genome shotgun sequence.
ACCESSION   DACDAF010000193 DACDAF010000000
VERSION     DACDAF010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1361
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.203"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            111..>1361
                     /locus_tag="IVZ69_002792"
     CDS             111..>1361
                     /locus_tag="IVZ69_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HAP8184800.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFK"
BASE COUNT          426 a          268 c          260 g          407 t
ORIGIN      
        1 tttgatgttg gtgaacttca ccaacatctt ttttgtataa aaaaatatag aaaagacacc
       61 ctgaaatcct ttagaattaa tttggctacc aattcatagg aggattcaag atgtctcata
      121 ctcagcttat caaagatacc ctaaatattc tagacctaaa tatctatttc gaggaaaatt
      181 gtttaactaa agaaaaatac aaagggcaaa tttgcttgat ttacaaagga actcttctgt
      241 acaagccaga agagtgttcc cattgtcttt gtgtcgtccc ctctaggatc attcgttggg
      301 ggacgacaac cgttcggttg ttactgaatg atgtgtctga gtatcgcact tatctggagc
      361 tgaagaaaca acgatttaaa tgtaagtctt gccaaagaac attcgtagcg gatacctctg
      421 ttgctgaaaa acactgtttc attagtcaaa aagttcgttg gtctgtcatt gctcgcttaa
      481 aagagaatac ttccatgacg gaaatcgctc gtcagaaaaa tatttccact tcttcggtct
      541 atcgtgtcat gaagcgattc taccgcccat tgaatccttt caaacagact ttgccaaagg
      601 tcttatgctt tgatgaattc aaatcggttc gaagtgttgc cagtgcaatg agttttatca
      661 tgatggacgg acaaagccat gcattattgg atattgtcga aaatcgacgc ttgccttatt
      721 tagaacgcta tttttctcgg ttttcattag cgactcgtga agccgttcaa ttgattgtta
      781 ttgatatgta tgcgccttat gtttcgttgg tgaaaaagct tttcccgaat gctcagttga
      841 tcatcgatcg tttccacatc gtccaacata ttggcagaac tttcttgaat catcgagtga
      901 aagaaaccac ggtacgactt aaaggaaatt cccactctca acgagggtta gggaaaaaat
      961 tgaagcgcta ttggaaactc ctacaaaaag aagaagcaaa gttaaactat gaaaaacggg
     1021 tttggcgtgc cagttttaaa gattatttga ctgaaagtga gattgccgat cgactgttag
     1081 ctgcttgtcc caacttacgc caaggctatc agttatacca agacattctt tatgcggtaa
     1141 agaaaagaga tcagtcacta tttgaggatt gtttaactag agacattagc ggtctgccag
     1201 aaacctatac aaccacttta cgaacgttta aaaagtttct gccacagatc caaaatgcgc
     1261 ttcactacag ctattcaaac ggaccattgg aatgcttaaa caaccacatc aaagtattaa
     1321 aacgcaatgc gtacggcttt cgcaactttt acaatttcaa a
//
LOCUS       DACDAF010000194         1349 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.204, whole genome shotgun sequence.
ACCESSION   DACDAF010000194 DACDAF010000000
VERSION     DACDAF010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1349)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1349)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1349
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.204"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            74..697
                     /locus_tag="IVZ69_002793"
     CDS             74..697
                     /locus_tag="IVZ69_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8184801.1"
                     /translation="MKIAYIRVSSIDQNEQRQIEEMKKFGAEKIFIEKQSGATITHRP
                     IFQEALEFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PHLDKFIKDLIIQILAMIAEQERTESKRRQAQVIKIAKANGVYKGRPKLYSADTKNPQ
                     RRLVYENIVKDLNEGIAISKIAKNYNITRQTIYRIKNDIEYNSNQMN"
     gene            complement(694..1296)
                     /locus_tag="IVZ69_002794"
     CDS             complement(694..1296)
                     /locus_tag="IVZ69_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184802.1"
                     /translation="MLKLISYAKKANSLSLVDNLDNLLPDKLIYDENEDNSQKQIIIF
                     ELYLKWLSSLSVSPESNDDDKYFANKLFQFIFPDYSSMPFFTLINFMLYVKEHLGYDD
                     LVEMIKAYDKEPYPFKGINTGSDMAMISGETVEEILANYKEQNIKTLELIKKNIKYYD
                     PLLANKENIDKLLNAIADSDVRSPRIDELKEEILMYKELF"
BASE COUNT          483 a          205 c          201 g          460 t
ORIGIN      
        1 ctttatagtg tataaaaaaa ttagtgttga ttttgagtgt attttaaata gtttgaggaa
       61 gtaggtaaaa attttgaaaa ttgcttatat tcgagtttcg tcgattgatc aaaatgagca
      121 acgccaaatt gaagaaatga aaaagttcgg cgcagaaaaa attttcatcg agaaacaatc
      181 tggagcaacg attactcatc gaccgatttt ccaggaagct ttagagtttg tccgagacca
      241 agatattttt attgtcgaag caatcgaccg acttggaaga aattacgacg aaatcattgc
      301 ttcagtcaat tacctaaaga agaaaaacgt gcagctgatc atcaccagtc taccgatcat
      361 ggctgaagca attggcaatc ctcatttgga taaattcatt aaagatttaa tcatccaaat
      421 tttggccatg attgcagagc aagagcgtac cgaatctaaa cgacgccagg cgcaagtcat
      481 taaaattgca aaagcaaatg gcgtctataa aggtcgtcca aaactctata gtgcagatac
      541 aaaaaatcct caacgacgtt tagtttatga aaacatcgtt aaggatttaa atgagggcat
      601 agctatttca aaaattgcta aaaactacaa tattactaga caaactattt acagaattaa
      661 gaatgatatt gagtataaca gtaatcaaat gaattaaaaa agttctttat acattaaaat
      721 ttcttctttt aactcatcaa ttctaggaga tctaacatca gaatcagcaa ttgcatttaa
      781 taacttatca atattttctt tattcgctag taaaggatca tagtatttta tattcttttt
      841 aattaattcc agagttttta tattttgttc tttgtaatta gctagaattt cttctacagt
      901 ttcgcctgaa atcatagcca tatctgaacc agtattgatt cctttgaatg gataaggttc
      961 tttatcatat gcctttatca tttctactaa atcatcatat cctaagtgtt ctttaacata
     1021 cagcataaaa tttattaatg taaaaaatgg cattgaagaa tagtctggaa atataaattg
     1081 aaacagtttg ttcgcaaaat atttatcatc atcattgctt tctggtgaca ctgacaggct
     1141 gctaagccac tttaaataca attcaaatat aattatttgt ttttgtgaat tatcttcatt
     1201 ctcatcataa ataagtttat cgggtaaaag attatctaag ttatctacta aagataggct
     1261 attagctttc ttggcataag atattaattt taaaatatta ttatttagga ataatctata
     1321 ttcttctcca gataattctt ctaaaaatt
//
LOCUS       DACDAF010000195         1340 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.205, whole genome shotgun sequence.
ACCESSION   DACDAF010000195 DACDAF010000000
VERSION     DACDAF010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1340
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.205"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            82..>1340
                     /locus_tag="IVZ69_002795"
     CDS             82..>1340
                     /locus_tag="IVZ69_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HAP8184803.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRI"
BASE COUNT          456 a          259 c          256 g          369 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag
//
LOCUS       DACDAF010000196         1320 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.206, whole genome shotgun sequence.
ACCESSION   DACDAF010000196 DACDAF010000000
VERSION     DACDAF010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.206"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            197..>1320
                     /locus_tag="IVZ69_002796"
     CDS             197..>1320
                     /locus_tag="IVZ69_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP8184804.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGL"
BASE COUNT          506 a          210 c          280 g          324 t
ORIGIN      
        1 ccaaagctct tagttgaaac gtgggtcgat gtctattcga tgttgaccga cgttttttct
       61 atgccttcag atttggtttt aagcgatatc tgtttagatg acattttgca aatggcttac
      121 aacaagagtg cttatgaagg atggaaaaac tatgcaataa accaatccca gaaaaactaa
      181 agaaaggagg taaaaaatgg ctaaaaagag aacagaagca gaagtaacat tcatagctaa
      241 cgatgacgga ttgaaatcta cgttaaaaga aatcagtgct gaattaacta aaaatagagc
      301 agaattaaaa ctagaacaag ctcaattaca acagactggt tctgaatcag acaagttagg
      361 aagtaaatta tcttctttag aaaagcagta tgaattacaa agtcaaaaag ttgaagtaac
      421 tagccaacgt ttagccaatg ccaaaaaata ttatggagaa aattccaccg aagttcagaa
      481 acttgagaga gaactgatta accaacaaac agcgcaacaa cgtttgtcaa acgaaattga
      541 taaaacgagt aatgcactag ctcaagcaaa aggcgaaata cagacgtacg agtctacaat
      601 gcaacagttg gatagtgaac aaaaaaatgt tcaagctagt gcttctctga ttgaatccga
      661 atacaaaaaa tggcaagcaa ctgctggtca atcagcttct gaatccgaga aattagcgaa
      721 agcccaagaa tatgtttctc aacaatctga aaatgcagag aaaacgatag atatcctgag
      781 acgacagtta gaagctacac agtctgagtt tggcgctaca tccacagaag caatgcagat
      841 ggaggcgaag cttaatgatg ctgaacgtga atttgaagag ttaggacaag ctgctaaaaa
      901 tgtagataca actaacttgg acgatatcgg aagcaaaata gatatgaata atctaatgga
      961 agcttctgac gttttaagcg acattggcga taagcttaca gaattaggga aacaagcagt
     1021 ggactctgct aatagtgtag gtagttccca gagtaaaata caagctaatt ttggtttgac
     1081 taaacaagag gctgaagaat taacgaatgt agccagagac atttattata aaggttttgg
     1141 agaatcgtta gatcagtcca cagatgcatt gattttggta aagcgtaatt taggcgattt
     1201 aaataatcaa gatttacaaa atatcacgga acaagctatg gtcctagaaa acaccatggg
     1261 cgctgatatg gatgaaacgt tacgtggtgt aaatggctta atggtcaatt tcggcttgag
//
LOCUS       DACDAF010000197         1320 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.207, whole genome shotgun sequence.
ACCESSION   DACDAF010000197 DACDAF010000000
VERSION     DACDAF010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1320
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.207"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            197..>1320
                     /locus_tag="IVZ69_002797"
     CDS             197..>1320
                     /locus_tag="IVZ69_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HAP8184805.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASEAEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLSKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGL"
BASE COUNT          507 a          208 c          280 g          325 t
ORIGIN      
        1 ccaaagctct tagttgaaac gtgggtcgat gtctattcga tgttgaccga cgttttttct
       61 atgccttcag atttggtttt aagcgatatc tgtttagatg acattttgca aatggcttac
      121 aacaagagtg cttatgaagg atggaaaaac tatgcaataa accaatccca gaaaaactaa
      181 agaaaggagg taaaaaatgg ctaaaaagag aacagaagca gaagtaactt tcatagctaa
      241 cgatgacgga ttgaaatcta cgttaaaaga aatcagtgct gaattaacta aaaatagagc
      301 agaattaaaa ctagaacaag ctcaattaca acagactggt tctgaatcag acaagttagg
      361 aagtaaatta tcttctttag aaaagcagta tgaattacaa agtcaaaaag ttgaagtaac
      421 tagccaacgt ttagccaatg cgaaaaaata ttatggagaa aattccaccg aagttcagaa
      481 acttgaaaga gaactgatta atcaacaaac agcgcaacaa cgtttgtcaa acgaaattga
      541 taaaacgagt aatgcactag ctcaagcaaa aggcgaaata cagacgtacg agtctacaat
      601 gcaacagttg gatagcgaac aaaaaaatgt tcaagctagt gcttctctga ttgaatccga
      661 atacaaaaaa tggcaagcaa ctgctggtca atcagcttct gaagccgaga aattagcgaa
      721 agcccaagaa tatgtttctc aacaatctga aaatgcggag aaaacgatag atatcctaag
      781 acgacagtta gaagctacac agtctgaatt tggcgctaca tccacagaag caatgcagat
      841 ggaagcgaag cttaatgatg ctgaacgtga atttgaagag ttaggacaag ctgctaaaaa
      901 tgtagataca actaacttgg acgatatcgg aagcaaaata gatatgaata atttaatgga
      961 agcttctgac gttttaagcg acattggcga taagcttaca gaattaggga aacaagcagt
     1021 ggactctgct aacagtgtag gtagttccca gagtaagata caagctaatt ttggtttgtc
     1081 taaacaagag gctgaagaat taacgaatgt agccagagac atttattata aaggttttgg
     1141 agaatcgtta gatcagtcca cagatgcatt gattttggta aagcgtaatt taggagattt
     1201 aaataatcaa gatttacaaa atatcacgga acaagctatg gtcctagaaa acaccatggg
     1261 cgctgatatg gatgaaacgt tacgtggtgt aaatggctta atggtcaatt tcggcttgag
//
LOCUS       DACDAF010000198         1277 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.208, whole genome shotgun sequence.
ACCESSION   DACDAF010000198 DACDAF010000000
VERSION     DACDAF010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1277
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.208"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..189)
                     /locus_tag="IVZ69_002798"
     CDS             complement(<1..189)
                     /locus_tag="IVZ69_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184806.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTK"
     gene            complement(190..1047)
                     /locus_tag="IVZ69_002799"
     CDS             complement(190..1047)
                     /locus_tag="IVZ69_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HAP8184807.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
BASE COUNT          359 a          258 c          185 g          475 t
ORIGIN      
        1 ttttgttctt cctctactct gtctttcaac attggaggaa gtttttattt cttgaacttg
       61 gtgcacttct aattgcttat tttcagatgg tgtaattgct tgctgctttt tctttgcttc
      121 tgcttctttt tttattttgg cgagtccttt gttgttccca aaaatatcaa gtcctttgat
      181 gtcagccaat tactccacct ccgcatacca attctcgtgt tcttccaatt ctttcaaaat
      241 actgataaat aattcgtggc ttttgcgatc ccattgtttt aagagacctt tctttgtctt
      301 ctccatcgta atacctgatc cgtcgtatcg ttttaagcgc gcatttttga gtacaacatt
      361 tttaatcaaa tgttccccat aaatctcttg ggcttgttta tacatttcct gatctactgc
      421 gtcaccgctt tccaacatga aaggaataac accagcaaca tataaatttg tatcaaattc
      481 tttcacaaaa aagtccatat actcaagata ttgcatcgca tttctcatcg attttacttg
      541 ggtctgtaag acgacgattg cccagtccgc aatgtacatc gcggatttac tatatacaga
      601 aatagaaggt gggacatcta aatagatgac gtcaaactca tcaaataatg gttctagctt
      661 ttctttcata tatttgaatt gggataatga atcattatat tggtctttga tccaatcatc
      721 atacatttca aaggacatgt ctgctggaag tatatagagg ttattgatta ctttatagac
      781 agcctcttta ggtggaagat tgtttatcaa cacgtcagtc acagtatttt cgtaaacaat
      841 cggttcacct tctccgcctc cttcttcgtt agtgaagttc atatgcgtta agttcatcac
      901 atcagaagta tttccttgca tatccaagtc aattatcaag gttctttttc cttcattaac
      961 tgctgattca aaccctaaca tttgcgcgca cgtactttta cctacgccac ctttaaaatt
     1021 accgattaca tatttcttcg ctaccacgtt cctacctctt ttcttttagc aatattcatt
     1081 tgatactatt ataacatatt tatttttagt tactaccaaa aaaaagatat atatgtacta
     1141 ccttataatt aataagtaaa aggtagtaca taaataagga aaagctgaaa tatattgatt
     1201 tatagctttc ctcaaagtaa tgacgttatt taatttatcg agaagcagag aatactcgcg
     1261 actttagtca tgtagac
//
LOCUS       DACDAF010000199         1276 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.209, whole genome shotgun sequence.
ACCESSION   DACDAF010000199 DACDAF010000000
VERSION     DACDAF010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1276
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.209"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(98..496)
                     /locus_tag="IVZ69_002800"
     CDS             complement(98..496)
                     /locus_tag="IVZ69_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HAP8184808.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(493..729)
                     /locus_tag="IVZ69_002801"
     CDS             complement(493..729)
                     /locus_tag="IVZ69_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HAP8184809.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            complement(889..1206)
                     /locus_tag="IVZ69_002802"
     CDS             complement(889..1206)
                     /locus_tag="IVZ69_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184810.1"
                     /translation="MKKVHSFLNYLMGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAY
                     SPTLILSTLTAGAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQ
                     YFG"
BASE COUNT          408 a          227 c          190 g          451 t
ORIGIN      
        1 tttatgaaaa aactattttg tatgattaaa cataaaaaaa tcagcatatt ccttaatgac
       61 atgctgatct aattgagaaa taaagttttt aattcgttca ttttattgcg gtttgtcgta
      121 aataactggt tatcttggac tttagtgaat cgaaatccaa tgaactagtg gtaatcatta
      181 tgataaaatc aacagcttct tgacgagaaa aagcaactgg acaattattc aattgaagaa
      241 acaacaacat ggcaacaaga gcagttcgtt tattgccatt atgaaaagga tgttttttag
      301 ctaaattaat tgctaaaatc gccgcttttt catagatttc aggatagagt tcttgattga
      361 atactgcttg tgaaggctgt ttgacggcca tatctaatgc atttgcatct tttacaccga
      421 tcatttcgcc tggcgagtga cgtaaaataa ctttcgcgtt gattttgata atttctttag
      481 tcgaaagata cctcataaat caaccaaatc ttttaacgcg tcttcatatt gattcatgat
      541 cgaatcaact aatgaatcaa tatcaggttc ttcttgtgct ttgatcattc gtacagaacc
      601 atcagattga aaaacataac tgattgcgtc acctgtctgc acacccatga attcttttac
      661 ttctggtggg atagttgtta catcgctatt gccagatttt ctaattttat actttttcat
      721 ttttttcata tttcgccacc ctctatacca ttctcattct atagtaagta cattatatcc
      781 aagtatatac ttttaatcaa tgtatatact tttattttgc tttttcttac gaaaaaatga
      841 caaagaaaaa agtttgtgac atgacttttg tcacaaactc tcgtattctt aaccaaaata
      901 ttgatgaaat acttgtgtaa taactggtag aaaataaata atgatcatag ccgctaccac
      961 caccaacaat tgttttcgct gtttctttcg ctttagcatg cttgtcgttt tatgaaaaaa
     1021 ataagtagcg cttttagctc ctgcagtcaa agtcgataaa atcaacgttg gtgaatatgc
     1081 tgtttgattg tgcgtcaatg acaacaactt cgtcccgtaa tcaggatact ttagaaatgc
     1141 ttggtacaca gccacaatcg tgattgctcc cataagataa tttaaaaatg aatgcacttt
     1201 tttcaaataa aaaaactcct tgctatctat ataaaatcag cctaccccaa cgtttttgct
     1261 tgattcactg atattt
//
LOCUS       DACDAF010000200         1248 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.210, whole genome shotgun sequence.
ACCESSION   DACDAF010000200 DACDAF010000000
VERSION     DACDAF010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1248)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1248)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1248
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.210"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(250..1110)
                     /locus_tag="IVZ69_002803"
     CDS             complement(250..1110)
                     /locus_tag="IVZ69_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184811.1"
                     /translation="MNIEKFITARKAANLSQKEVSEGICTQATLSKFENNGQVPSLKI
                     LIKLCNRINLPLVELFSSMNVINTQLDEQLEKAEFSLITSEYEQLTQILAAIDPKVID
                     ESELIARYYYLKGFEMIFTNAPITDVLFHFDQLLMAETANTLFRLLAYTGIGMVYARE
                     KELEKAEVYFNRVFEKIYTYPIRTTEDIWRVLNIVFHCGVFFAQDGDLETSDALLNYA
                     IDICSDNHLTYYLARAAAQLAKNAQAKNKSKAEVLELIQDALAFAKINKNKKLIDELN
                     HMKKMILLIN"
BASE COUNT          378 a          237 c          182 g          451 t
ORIGIN      
        1 aataagggaa acaaacaaca catttttgtg tgttgcttat ttccctctaa ctatcgtttt
       61 ctatttgatg gttaacctac ttaaaataaa tactgcaacg acaaacggag atcaagcatg
      121 ctttgtaacg tattttacga taattacgac tttattttat tactctatct tgctgccata
      181 cccgtctatc cctaatcatc tttggtgaat tttttcaaag ttagcataac aaaaataagt
      241 attttttcct tagttaatca atagtatcat ttttttcata tgatttaatt catcaattaa
      301 ttttttgttt ttattaattt tagcaaaagc tagtgcatct tgaatcaatt cgagcacttc
      361 tgccttcgac ttatttttag cctgtgcgtt cttcgctaat tgggcagcag ctcgtgctaa
      421 gtaataagtc aaatggttat ccgaacaaat atcgattgcg taatttagta gtgcatcact
      481 tgtttccaaa tcaccgtctt gcgcaaaaaa aacaccacaa tgaaagacga tatttaacac
      541 ccgccagata tcttctgttg tacgaatcgg atacgtataa attttttcaa acactcgatt
      601 gaaataaact tctgcttttt ccaactcttt ttctctagca tagaccattc caatacctgt
      661 atatgccaat aaacgaaaca acgtgttggc tgtttctgcc atcaacaact gatcaaaatg
      721 gaacaacaca tccgtaattg gtgcattcgt aaaaatcatt tcaaatcctt ttagatagta
      781 gtaacgtgca atcagctcag actcgtcaat taccttggga tcaatggctg ctaaaatctg
      841 tgtcaattgt tcatattcac tcgtaatcag tgaaaactct gctttttcta gctgttcatc
      901 aagttgtgta ttgatcacgt tcatcgaaga aaaaagttca actaacggaa gattgattcg
      961 attacataat ttgattaaaa tttttaacga agggacttga ccattgttct caaatttact
     1021 taatgttgct tgtgtacaaa ttccttcaga cacttctttt tgagataagt tggcagcctt
     1081 tcttgccgta ataaattttt caatgttcat tattttctct ccaatcagac ctcacacgaa
     1141 aatcatttct gtctcgattt tagcatgttt tctttgggaa tgctttaggt tctgttgcaa
     1201 agttttaaat aaagaataaa gtcccttacg gtatctatga tttaagct
//
LOCUS       DACDAF010000201         1246 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.211, whole genome shotgun sequence.
ACCESSION   DACDAF010000201 DACDAF010000000
VERSION     DACDAF010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.211"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            200..742
                     /locus_tag="IVZ69_002804"
     CDS             200..742
                     /locus_tag="IVZ69_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184812.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            832..>1246
                     /locus_tag="IVZ69_002805"
     CDS             832..>1246
                     /locus_tag="IVZ69_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HAP8184813.1"
                     /translation="MDELKRTEIQIIDKKERPKNGFVLSEKTDLENTEAFNKESVKDL
                     RKLPTKDINGKDFTSKDFEKYDLTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIV
                     GVVTDPVDDNGENKEAIEKSKLIHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          238 g          353 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DACDAF010000202         1232 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.212, whole genome shotgun sequence.
ACCESSION   DACDAF010000202 DACDAF010000000
VERSION     DACDAF010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.212"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            249..569
                     /locus_tag="IVZ69_002806"
     CDS             249..569
                     /locus_tag="IVZ69_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184814.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            587..1018
                     /locus_tag="IVZ69_002807"
     CDS             587..1018
                     /locus_tag="IVZ69_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP8184815.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
BASE COUNT          451 a          171 c          204 g          406 t
ORIGIN      
        1 ctaaattcaa ttgacagtat ctgagtaata ctctatacta agagcataat taaataagac
       61 ataaaaacat tgattttaaa gctttcttgg cggtctgcat ttacatatca atagtgtttt
      121 ttgttgtctt tttagttgtt aaatctgttt acaagatata gtatagctcg ttactcagaa
      181 ttagtcaaat tatttctgcg tatttttcta aacttttttt gtaaacattt agaaaggttg
      241 ttttatcgat gaatacctat gaaataataa aagacttggc gaagaggaaa aagatatcta
      301 tacggcagtt agaaattaat tttggatatt ctaacggtta tctagcaaag tggaaaaata
      361 atactcctaa ttcagatgaa ttaagtcgga ttgctgacta tttcgatgtc tctgtagact
      421 accttctagg tagagaagaa agagaaaccc ctaaacatgt ggatttatca gaagacgata
      481 ctgttttttc ttttgatgga aaagaaatat ctaaggagac aatgcgtaaa gcgattgcaa
      541 ttgctaaagc tttagaggaa aatgaatagt tggagtgatg gtttgtatgt atttgaaatt
      601 gaaagaaatg ttgagcgaat acaatttgaa agtagtttat atggagatga aagagcctgg
      661 tttctactat ccaaaaccca gaatcatttt tttgaatgaa aatctatacg gtgaaactgc
      721 agaagccttt catttatctc atgaacttgc acatttcagc gcctctcatt ttgaattttc
      781 agttttgtac gatacttcta caacttttca ctcaaaattt gaaacagaag cagataaaat
      841 agctattcta attttattaa atatctatat tgagaacgaa ctgactgatg aatctcagtt
      901 taatctcgaa aaatttatgg agtattattc tattcagaat aagctcagat acacttgtta
      961 tgctgtctgc caatgctatt ttaagaaaaa atattcttac gcaaggcaat atgtatgaat
     1021 acatcaagaa ttattaaaaa aaccgatttc agcaaaacat taaaaaagcc cgtgctgcaa
     1081 cacgggctct ttcctcatat atgagcttct acaaaaaaaa tcatatcaca gaaatgagga
     1141 agaaaaaatg gaaaaagaga ttttaataaa atctccagga aaaaccttga ttaaagtaac
     1201 tgatgattct atttcaatta ttagaaaagg at
//
LOCUS       DACDAF010000203         1232 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.213, whole genome shotgun sequence.
ACCESSION   DACDAF010000203 DACDAF010000000
VERSION     DACDAF010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.213"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            141..1181
                     /locus_tag="IVZ69_002808"
     CDS             141..1181
                     /locus_tag="IVZ69_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein RepA"
                     /protein_id="HAP8184816.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESDISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYA
                     SSPSTITKDWLE"
BASE COUNT          496 a          177 c          204 g          355 t
ORIGIN      
        1 ttcattttat ttctgatttt aggtagtatt taattaaaaa acagttttaa tgcgtttgca
       61 ttttttattt atctttgcta ttttcgaaaa gagtaggtaa ttttacataa ataaaacaac
      121 gtgaaagtag aggatctaca atgactgatt ttaaattttt taaggcggat agagtttaca
      181 acgaattatt ttatcaattt ccaaaagtct ttattgtttc tgacgaatac aaaaaaatga
      241 aagattcaac taagattgcc tatatgcttt taaaagcaag attagagatc gcaatcagca
      301 aacggcaaat cgatgaagaa ggtaatgttt attttactta tacgacaaat gaactatgta
      361 gagtattaaa ctgccaaaaa caaaaagcga tagcaatcaa aaaagagttg gaatcctttg
      421 gtttattatt acaaaagcag atgggattta acaaacagtt agggaaaaat aatcctaata
      481 gactatatct agcagaatta aaagtctcag aaaatgatat ctacttactc gaaaaatttg
      541 atagagagaa tagggaaaac gttgataaat cagagggtat gaaaatcata cccaccctcg
      601 acgaaaaatc agacgctgaa tcccttgggg ctcaagaggg tatgaaaatc ataccgtgcc
      661 aaaacgttga taaatcagag ggtatgaaaa tcataccaga acttaataat aatatattag
      721 acactaatag acacaatata gacactgaaa aagaccgcct acaagatcaa ttgttgttag
      781 acaattttga gacaattatg acaaacgaca gcattgctac gtttgtccct gaacgagtat
      841 taaatttgat aaaaacattt tcttcaagtt acagtgaagc tcaaaaaacc gtccagacta
      901 ttcataatgc aaagaaaaaa gctgaaatag aaagtgatat ttcgatagtt tttgaagaac
      961 tcgatagtta ttatgtcaat gcagaacaag aattatacac gacactgtta aaagcctatc
     1021 aaaaattaaa aaccgaaaaa gtcgaaaata tccagaacct gatttttgtc tatgtaaaaa
     1081 attggtttat cgaaaaacca atagctgcta aagtatcaag tgaaaaacgt ttgaattatg
     1141 caagctcccc aagcactatt acgaaagact ggttagagtg aaactttact gacaaagtga
     1201 ttgttgcttc atggagtaac attaaaatta aa
//
LOCUS       DACDAF010000204         1229 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.214, whole genome shotgun sequence.
ACCESSION   DACDAF010000204 DACDAF010000000
VERSION     DACDAF010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1229
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.214"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            37..375
                     /locus_tag="IVZ69_002809"
     CDS             37..375
                     /locus_tag="IVZ69_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8184817.1"
                     /translation="MNGIEDENLRRLINSLVIELYKYQAESERKKIKERQAQGIEIAK
                     KKGKFKGRQLKFKKNDPRLKHAFDLFLNGLSDKEVEEQTGINRRTFRRYRARYNVTVD
                     QRKNNEKRDS"
     gene            467..1208
                     /locus_tag="IVZ69_002810"
                     /pseudo
     CDS             467..1208
                     /locus_tag="IVZ69_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320596.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          462 a          198 c          253 g          316 t
ORIGIN      
        1 aggggggcaa ccctggaagt cttaaattta ccctcaatga atggtattga agatgaaaat
       61 ttaaggcgtt tgattaatag ccttgtcatt gaattgtaca agtatcaagc agaatcagaa
      121 cgaaaaaaaa ttaaggaacg tcaggcacaa ggaatcgaaa ttgctaagaa aaaaggcaaa
      181 ttcaaaggtc ggcaactgaa atttaaaaaa aatgatccac gtttaaagca tgctttcgat
      241 ttgtttttga atggtttatc cgataaagaa gttgaagaac aaactgggat caatcgccga
      301 acgtttagaa ggtatcgagc aagatataac gtgacagtag atcaaagaaa aaacaatgaa
      361 aagagggata gttaatgagt acggttattt tagctgaaaa acaagccagg cattagccta
      421 cgcaagtgct ttaaaacaaa gcaccaaaaa agacggttat tttgagatca aagacccact
      481 atttacagat gaaacgttta tcacctttga ttttgggcat ttagtggaat tagcagaacc
      541 aggtcattat gacgaaaagt ggcaaaattg gaaacttgaa tctttgccga tttttcctga
      601 tcgatacgat tttgaagttg caaaagataa gggaaagcag tttaaaattg ttgcagaact
      661 tctcaaaaag gcaaatacaa ttattgttgc aacagatagc gacagagaag gtgaaaatat
      721 cgcctggtcg attatccata aagcaaatgc cttttcaaaa gataaaacat ttaaaagact
      781 atggatcaat agcttagaaa aagatgtgat ccgaagcggt tttcaaaatt tgcaaccagg
      841 aatgaattac tatccctttt atcaagaagc gcaaacacgc caaattgccg attggttgat
      901 cggcatgaac gcaagccctt tgtatacgtt aaatttacaa cagaagggcg tacaaggtac
      961 attttcacta ggacgtgttc aaacgcccac cttatacctt atttttcagc gccaggaagc
     1021 tagtataaaa gtaaaacaag ggtcatttaa gggcgttcta agccccacac agcgttttaa
     1081 aacccaagag gagctttttt gcttttgttt cttctaaaca agctaaaata ggcaatcaag
     1141 aggggataat tgctgatgtt caaaccaaag agatggatag gctacaatta actagacaga
     1201 aaaattaagg tgtgtagact agaagaaaa
//
LOCUS       DACDAF010000205         1215 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.215, whole genome shotgun sequence.
ACCESSION   DACDAF010000205 DACDAF010000000
VERSION     DACDAF010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.215"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            71..1027
                     /locus_tag="IVZ69_002811"
     CDS             71..1027
                     /locus_tag="IVZ69_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184818.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
     gene            complement(1081..>1215)
                     /locus_tag="IVZ69_002812"
     CDS             complement(1081..>1215)
                     /locus_tag="IVZ69_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HAP8184819.1"
                     /translation="FNQVNQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA
                     "
BASE COUNT          427 a          179 c          208 g          401 t
ORIGIN      
        1 gttgacaggg aatcctaaaa acattcggct ttttttatat aatcttttta actcaacaga
       61 gataagtttt gtggaattgt atacgctacc tataattata aaaacagaaa aaatgttaaa
      121 agatttaaaa cagtattatc ctctgtctgc ttatgaaaaa aagaaattat tccacttttt
      181 agcaatcaac ctgttggctg aacaagctga ttctttagat attgctagca atcagtcgct
      241 atttttttcg gatataggat tttaccactt aaaaggagta ttaggagaaa aatccgttat
      301 ttttatcaat aagacactct cttggcttta tcttcatgat aaattggatc aaaaatactt
      361 gagaaaaaat gaagatgaaa caatcgaatg gttgaatgaa cgattcattg aaagttttga
      421 aaatcagttt aatctgttgc gagaagagac gagccaattg atccgaagag agttaaccaa
      481 aatacatttt aaacttttgc attacactat taataaagct gatgaatttc cacttgatgt
      541 ttcttttttt agagaaaact atccagcatt ttattgctat ttgatagagt atataaatga
      601 tctaacgtca aaacgcaaag agttgcttca agataaattt tttctttttt tcagttattt
      661 attattattg atcaatcaca tacccattca actgatttct gaaccagtaa agatcatcat
      721 cgatttttct tatggtgctg cctataatca atttatcaag aaaaatttaa gcttgtacat
      781 taatctgaac acggaagtga tagaggcagg aaagcctgag ttcccggatg ttataatcac
      841 gaataggaat aatctatatg aagaaagtgc atctcaagta gtggtttggc tcgatccgcc
      901 aagagcagta gactggggga atcttacaaa gattttgttg actatccaag aagagaaata
      961 caaagacagc aaaattgaca agcaaataga cgattttcct gaagaaatca tcgacaggat
     1021 cgaatagtga acttctttta gaaagtccga ctgctttttc taaaaatatt atttgtcaaa
     1081 ttaagcgaga caaaactttc catttacgta actcaaaaaa acttctaatg gtgtttggta
     1141 atttagtgat tttctaggga tatggtttct tttggacgca acggatgaga tgaatccttg
     1201 attgacttgg ttgaa
//
LOCUS       DACDAF010000206         1195 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.216, whole genome shotgun sequence.
ACCESSION   DACDAF010000206 DACDAF010000000
VERSION     DACDAF010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1195
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.216"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..1076
                     /locus_tag="IVZ69_002813"
     CDS             <1..1076
                     /locus_tag="IVZ69_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HAP8184820.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          211 g          332 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tcttg
//
LOCUS       DACDAF010000207         1177 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.217, whole genome shotgun sequence.
ACCESSION   DACDAF010000207 DACDAF010000000
VERSION     DACDAF010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.217"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            121..975
                     /locus_tag="IVZ69_002814"
                     /pseudo
     CDS             121..975
                     /locus_tag="IVZ69_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            complement(1061..>1177)
                     /locus_tag="IVZ69_002815"
     CDS             complement(1061..>1177)
                     /locus_tag="IVZ69_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP8184821.1"
                     /translation="TIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT          410 a          190 c          222 g          355 t
ORIGIN      
        1 atattttaaa ataaaagata gcgtaaaata ttttgtgtaa atagaaattt agggtagaaa
       61 aaaaagtcca ttctgtaaaa ttaaagttac cacacagaaa ttttatagga ggactttctc
      121 atgactaaat ttactataga aattatgcaa acactactca ataaagggga tttagatgaa
      181 ttatttcagg atcatttaga gcgagcgatt aattcacttc tacaagcaga gctaactgct
      241 tttttagatt acgaaaaata tgatcgaaat ggattcaatt caggaaattc ccgtaacggg
      301 aattattcac gtacatttaa aacagaatat ggcgagttga atttaactat tcctagagat
      361 cggaatggcg aattttctca acaaacacta ccagcatata agcgaaccaa tgattcatta
      421 gaaacgacca ttatccaatt atttcaaaaa ggcattacta tggctgaaat ctccaaatta
      481 attgaaaaaa tgtatggtca ccactatacg ccacaaacaa tctccaacat gagtaaattg
      541 gtggctgaag atgttttagc ttttaaagaa agaacgttag aagccaatta ttccgttata
      601 tttatggatg cgacgcatat ccctgtgaag cgacagactg tttcgaagga agcagtgtat
      661 attacgattg gtattcgttt ggatggaacc aaagaagttc ttgggtttac tattgcccca
      721 actgagtctg cttatatttg gaaagaagtt cttcaagatc ttagaaaacg tgggttagaa
      781 gaagttttat tagtagtgac agacggatta agctgtattg aagaaagtat ccatagtgtg
      841 tatccgaatg cccaatttca acaatgttgt gtgcatgtat ctagaaatat cgctcataaa
      901 gttcgtgttc gaggtcgaaa agaaatttgt gaggatttca aattggttta ccaagcgaat
      961 tcaaaagaag aggcgtaagc gccccataga acagtacctt actaacggtt ctgttgcaaa
     1021 gttttaaata aagaataaaa tcccttacgg tatctatgat ttaagctggg attcccaata
     1081 ataccttgat ttcagtacag accgaaaacc cgaagagagt gccttctttt cgggttttct
     1141 tatataatcc tcggatggct tccatgcctt taatcgt
//
LOCUS       DACDAF010000208         1177 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.218, whole genome shotgun sequence.
ACCESSION   DACDAF010000208 DACDAF010000000
VERSION     DACDAF010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1177
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.218"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            496..1113
                     /locus_tag="IVZ69_002816"
     CDS             496..1113
                     /locus_tag="IVZ69_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8184822.1"
                     /translation="MAKIGYARVSSKEQNLDRQLQALQGVSKVFSDKLSGQSVERPQL
                     QAMLNYIREGDIVVVTELDRLGRNNKELTELMNAIQQKGATLEVLNLPSMNGIEDENL
                     RRLINNLVIELYKYQAESERKRIKERQAQGIEIAKSKGKFKGRQHKFKENDPRLKHAF
                     DLFLNGCSDKEVEEQTGINRRTFRRYRKRYNVTVDQRKNKGKRDS"
BASE COUNT          424 a          144 c          267 g          342 t
ORIGIN      
        1 tatgatacgt gtttgttttt ctgtgctgtt tagtgaatga ttagcagaaa tatagagagt
       61 aagattttaa ttaattatta gggggagaag gagagagtag cccgaaaact tttagttggc
      121 ttggactgaa cgaagtgagg gaaaggctac taaaacgtcg aggggcagtg agagcgaagc
      181 gaacacttga tcttttaagt tgctatcttt ttaaggtcaa tagagtatac ttatttgtcc
      241 taatatgatt ttagcagtat aattgacttg gtgaataggt catttaagtt gagcataata
      301 ggaggattaa aatgaaaaaa tttatttatc gagttttaga aaatgacgaa gtggtggcta
      361 tttttaatga gcaacaatat gcgcatgatt ttatcgctta cgaaaagaca atttctgata
      421 agcaatttga aattgaaaaa gtagatatag ctgattggtt attgcaaccg agagaatttt
      481 agaggttggt tgaaaatggc taaaattggt tatgcacgtg tcagtagcaa agaacagaac
      541 ttagatcggc aattacaagc gttacagggc gtttctaagg tcttttcaga caaattaagc
      601 ggtcaatcgg tcgaacgtcc acaattacaa gctatgctta actatattcg tgaaggggat
      661 attgttgtag ttactgaatt agatcgatta ggacggaata ataaagaatt aacagaattg
      721 atgaatgcca ttcaacaaaa aggagcaacg cttgaagttt tgaatttgcc ctctatgaat
      781 gggattgaag atgaaaattt aaggcgtttg attaataatt tagtgattga attatataag
      841 tatcaagcgg aatcagaacg caaacgtatt aaagaacgac aagcccaagg gattgaaata
      901 gctaagtcaa aaggaaaatt caaaggtcgt cagcataaat ttaaagaaaa tgatccacgt
      961 ttaaaacatg cttttgattt atttttgaac ggttgttccg ataaagaagt tgaggaacaa
     1021 actggaatta atcgcagaac gtttagaagg tatcgtaaaa gatataacgt gacagtcgat
     1081 caaagaaaaa acaagggaaa gagggatagt taatgagtac agttatttta gctgaaaaac
     1141 caagccaggc gttagcctat gcccaggcat ttaatca
//
LOCUS       DACDAF010000209         1174 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.219, whole genome shotgun sequence.
ACCESSION   DACDAF010000209 DACDAF010000000
VERSION     DACDAF010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.219"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(58..142)
                     /locus_tag="IVZ69_002817"
     tRNA            complement(58..142)
                     /locus_tag="IVZ69_002817"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(106..108),aa:Leu,seq:caa)
     gene            complement(163..233)
                     /locus_tag="IVZ69_002818"
     tRNA            complement(163..233)
                     /locus_tag="IVZ69_002818"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(199..201),aa:Cys,seq:gca)
     gene            complement(279..350)
                     /locus_tag="IVZ69_002819"
     tRNA            complement(279..350)
                     /locus_tag="IVZ69_002819"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(316..318),aa:Gln,seq:ttg)
     gene            complement(362..434)
                     /locus_tag="IVZ69_002820"
     tRNA            complement(362..434)
                     /locus_tag="IVZ69_002820"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(399..401),aa:His,seq:gtg)
     gene            complement(437..510)
                     /locus_tag="IVZ69_002821"
     tRNA            complement(437..510)
                     /locus_tag="IVZ69_002821"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(476..478),aa:Trp,seq:cca)
     gene            complement(517..597)
                     /locus_tag="IVZ69_002822"
     tRNA            complement(517..597)
                     /locus_tag="IVZ69_002822"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(561..563),aa:Tyr,seq:gta)
     gene            complement(599..674)
                     /locus_tag="IVZ69_002823"
     tRNA            complement(599..674)
                     /locus_tag="IVZ69_002823"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(639..641),aa:Phe,seq:gaa)
     gene            complement(710..782)
                     /locus_tag="IVZ69_002824"
     tRNA            complement(710..782)
                     /locus_tag="IVZ69_002824"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(747..749),aa:Asp,seq:gtc)
     gene            complement(792..864)
                     /locus_tag="IVZ69_002825"
     tRNA            complement(792..864)
                     /locus_tag="IVZ69_002825"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(829..831),aa:Val,seq:tac)
     gene            complement(880..951)
                     /locus_tag="IVZ69_002826"
     tRNA            complement(880..951)
                     /locus_tag="IVZ69_002826"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(916..918),aa:Glu,seq:ttc)
     gene            complement(966..1054)
                     /locus_tag="IVZ69_002827"
     tRNA            complement(966..1054)
                     /locus_tag="IVZ69_002827"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1018..1020),aa:Ser,seq:gga)
     gene            complement(1094..1167)
                     /locus_tag="IVZ69_002828"
     tRNA            complement(1094..1167)
                     /locus_tag="IVZ69_002828"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1131..1133),aa:Asn,seq:gtt)
BASE COUNT          336 a          307 c          264 g          267 t
ORIGIN      
        1 ataaaagatg ttatttaatt tctcaataaa aaactaagat gaagacatct tagtcaatac
       61 cggcggccgg ggtcgaaccg gcacgccctc aacgggcact ggattttgag tccagcgcgt
      121 ctgccaattc cgccacgccg gcaagttgat ttattagtac taaggcggta accggatttg
      181 aaccggtgat gaaggttttg cagacctctg ccttaccact tggctatacc gccattatac
      241 tattatcaat ctacaaaata aagaataaat tatagaaact ggggtagctg gattcgaacc
      301 aacgcatgag ggagtcaaag tcccttgcct taccgcttgg ctatacccca agaataaaaa
      361 gggcgaatga tgggaatcga acccacgaat gccggagcca caatccggtg cgttaaccac
      421 ttcgccacat tcgccatggc aggggcagca ggaattgaac ccacactaac ggttttggag
      481 accgctgttc tacctttaaa ctatgcccct ataaaatgga ggagagtgga ttcgaaccac
      541 tgaaccctaa ggaacggatt tacagtccgt cgcgtttagc cacttcgcta ctcctccatg
      601 gtggcgcggg acagaatcga actgccgaca cacggagctt caatccgttg ctctaccaac
      661 tgagctaccg cgccatattt taaaattatt aattgaataa caagaacgac ggttccgacg
      721 ggaatcgaac ccgcgatctc ctgcgtgaca ggcaggcatg ttaaccccta caccacggaa
      781 ccagttcatt atggaggtta acgggatcga accgctgacc ctctgcttgt aaggcagatg
      841 ctctcccagc tgagctaaac ctccaacatt caattaaaat gacccgtacg ggattcgaac
      901 ccgtgttacc gccgtgaaag ggcggtgtct taaccgcttg accaacgggc caggtaaatt
      961 tgctacggag agtaagggat tcgaaccctt gagacagttt gcaccatcta catgatttcc
     1021 aatcatgctc cttcggcctc tcggacaact ctccagagtg aaagaagctc aatactcttt
     1081 ctcaaaatga gaactccggc agtaggactc gaacctacga catcatgatt aacagtcatg
     1141 cgctactacc aactgagcta tgccggaata acat
//
LOCUS       DACDAF010000210         1132 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.220, whole genome shotgun sequence.
ACCESSION   DACDAF010000210 DACDAF010000000
VERSION     DACDAF010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.220"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(101..295)
                     /locus_tag="IVZ69_002829"
     CDS             complement(101..295)
                     /locus_tag="IVZ69_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184823.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
BASE COUNT          398 a          163 c          148 g          423 t
ORIGIN      
        1 ttaaaatatg tgcttttgtt agaaaaatca atacataaat tatcatatct gtatatgtca
       61 tttaggtatt tcagttatgt tataatagtt ttgctgtctg ctaccccggc ctaatctggc
      121 aaggggagga ggagatataa tgaaatacct ttttgatttt gtttttgcaa tcaagccact
      181 tgcagatgta gtgtgcagtt acctctgcaa atggcttgat tgcaaaattg ccaaaaaaga
      241 cagtaagcct acccgttaat tctataatat agaaacgtaa aaaaaacccc atcagcctgc
      301 acgctgatgg ggtttggtga tataatgaaa tacctctttg ttactcataa ttataccata
      361 attagtcacg aatgcaacca atagaaaaaa ctacttagaa cggtagatca tcgctaataa
      421 caatgcattg tccaccaaat ggattttgtg aagcattaaa tacattgtta ttaattgtcg
      481 ctgcttttaa ctaggcctct ccccttctat tataaaagaa gatatatatc atttcttaat
      541 tacctactac cttaaaccaa aatttaagta ctacctaatt taagtagtac ttaaacaatc
      601 taaaaaatag ttatcccaat tgttatgctt ttataatacg attatttgta acaaaatgaa
      661 tattatataa ttaaacacta ccatatttag gtagtgttta attattagca aaacaaaaaa
      721 tatttattct attctcttaa cttcaactaa gttatgctgc acacctttat ataaatcata
      781 tgcaactcat tagctagaca aactacaagc atgtagtttt atctgttaat tatgtactac
      841 ctaaataaag tagtttataa ttagcaagta tatatattta aaaatttaag attaattttt
      901 ttatgacttg tacaaattta tctgatattc tcttattaag aactacctaa tttgggtagt
      961 tcttattttt tacattttaa gtagtattta attgcaattt ggtagtattt ttttattatc
     1021 ttattcttag aacggtagta cttaatataa atataggtag tatctaattt aagtattaat
     1081 ggtagtatct aaattaacag gtagtatgta actactttaa agtaattttt tt
//
LOCUS       DACDAF010000211         1073 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.221, whole genome shotgun sequence.
ACCESSION   DACDAF010000211 DACDAF010000000
VERSION     DACDAF010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1073)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1073)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1073
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.221"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            2..>1073
                     /locus_tag="IVZ69_002830"
     rRNA            2..>1073
                     /locus_tag="IVZ69_002830"
                     /product="23S ribosomal RNA"
BASE COUNT          329 a          214 c          308 g          222 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg taatagctca ctagtcgagt gaccctgcgc cgaaaatgta
     1021 ccggggctaa acatattacc gaagctgtgg agtacacctt taggtgtatt ggt
//
LOCUS       DACDAF010000212         1070 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.222, whole genome shotgun sequence.
ACCESSION   DACDAF010000212 DACDAF010000000
VERSION     DACDAF010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.222"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            25..>1070
                     /locus_tag="IVZ69_002831"
     CDS             25..>1070
                     /locus_tag="IVZ69_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HAP8184824.1"
                     /translation="MTELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNII
                     DTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFINKID
                     QNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLEKY
                     MSGKSLEALELEQEESIRFQNCSLYPVYHGSAKSNIGIEQLIEVITNKFYSSTYRKKS
                     ELCGNVFKIEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSINGELCKI
                     DKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLD
                     ALLEISDSDPLLQY"
BASE COUNT          386 a          169 c          223 g          292 t
ORIGIN      
        1 agcttattat ataacagtgg agcgattaca gaattaggaa gcgtggacaa aggtacaacg
       61 aggacggata atacgctttt agaacgtcag agaggaatta caattcagac aggaataacc
      121 tcttttcagt gggaaaatac gaaggtgaac atcatagaca cgccaggaca tatggatttc
      181 ttagcagaag tatatcgttc attatcagtt ttagatgggg caattctact gatttctgca
      241 aaagatggcg tacaagcaca aactcgtata ttatttcatg cacttaggaa aatggggatt
      301 cccacaatct tttttatcaa taagattgac caaaatggaa ttgatttatc aacggtttat
      361 caggatatta aagagaaact ttctgccgaa attgtaatca aacagaaggt agaactgtat
      421 cctaatatgt gtgtgacgaa ctttaccgaa tctgaacaat gggatacggt aatagaggga
      481 aacgatgacc ttttagagaa atatatgtcc ggtaaatcat tagaagcatt ggaactcgaa
      541 caagaggaaa gcataagatt tcagaattgc tccttgtacc ctgtttatca tggaagcgca
      601 aaaagcaaca tagggattga gcagcttata gaagtgataa cgaataaatt ttattcatca
      661 acatacagaa agaagtctga actttgcgga aatgtcttca aaattgaata ttcggaagaa
      721 agacaacgtc ttgcatatgt acgcctttat ggcggaatcc tgcatttgcg ggattcggtt
      781 agaatatcgg aaaaggaaaa aataaaaatt acagaaatgt atacttcaat aaatggtgaa
      841 ttatgtaaaa ttgataaggc ttattccggg gaaattgtta ttttgcaaaa tgagtttttg
      901 aagctaaata gtgttcttgg agatacaaag ctattgccac agagagagag aattgaaaat
      961 ccgctccctc tgctgcaaac aactgttgaa ccgagcaaac ctcaacaaag ggaaatgtta
     1021 cttgatgcac ttttagaaat ctccgacagt gacccgcttc tacaatatta
//
LOCUS       DACDAF010000213         1009 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.224, whole genome shotgun sequence.
ACCESSION   DACDAF010000213 DACDAF010000000
VERSION     DACDAF010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1009
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.224"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..>1009
                     /locus_tag="IVZ69_002832"
     CDS             <1..>1009
                     /locus_tag="IVZ69_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184825.1"
                     /translation="ENPNLMPYITEPWVGPLLGNGHTVKDSVKRVITHTKTRTANSGD
                     ILSLGLGIPCTAEANNRYLITTLRPSTTYTLSVTMSVGSDWTGETNTIGVRLRYLNEQ
                     GGIELPINALIPANVERDKMVTHTFTGITKDNVTSITNCYVEIFSLNSEYKGTVSVSY
                     DVKLKAHYPNLLDGPYWLGKVPLGENIADPTVVFPHKTSEYMVYGRRNTENYIADQTY
                     TISMKATKLTVQSFAVYIAAGRVKVGDMKPTEGLANTWELTFTVTKQHIDSGVTNYLE
                     IYQYPSATKGAVQIEWLKLEKGNTRTPNISEYKYRGTGMRDSNNPKDYVWDLAPEYVE
                     D"
BASE COUNT          352 a          176 c          202 g          279 t
ORIGIN      
        1 cggagaaccc gaatttaatg ccatatatta cagaaccttg ggttggacct ttgttaggta
       61 atggacatac agttaaagat agtgttaaaa gggttataac tcatactaaa actagaacag
      121 ctaattccgg cgacatatta tcgcttggct taggtattcc gtgtacagcg gaagctaata
      181 ataggtatct tataaccact ttacgaccat ctacgacata cacattaagc gttactatga
      241 gtgtcggttc agattggact ggagagacca atactatagg ggttaggctt agatatttaa
      301 atgaacaagg tggtatagaa ctgcccatta atgcattaat accagcaaat gtagaacgcg
      361 ataaaatggt cactcataca tttactggta taacaaaaga taatgtaact agcataacaa
      421 actgttatgt tgaaatattc tcacttaata gtgaatataa aggaacggtt agtgtcagct
      481 atgacgttaa gttaaaagca cactacccta acttactaga tggcccttac tggttaggta
      541 aagttccttt aggcgagaat attgctgacc ctacagttgt ctttccacac aaaactagtg
      601 aatatatggt ttatggtaga cgcaatacag aaaactatat cgctgaccaa acatatacca
      661 tatcaatgaa agcaactaaa ctaacagttc aatcgtttgc cgtgtatatt gctgctggcc
      721 gcgttaaagt aggagacatg aagcctactg aggggttagc taatacatgg gagttaactt
      781 ttactgtaac taagcaacat atagatagtg gggtaactaa ttatctggaa atataccaat
      841 acccgtcagc tacaaaagga gctgttcaaa ttgagtggct caaactagaa aaaggcaata
      901 ctcgaacccc gaatattagt gagtataaat atcgtggtac tggtatgcgt gattcaaaca
      961 atccaaaaga ttatgtttgg gatctagcac cagaatatgt cgaagataa
//
LOCUS       DACDAF010000214         1000 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.225, whole genome shotgun sequence.
ACCESSION   DACDAF010000214 DACDAF010000000
VERSION     DACDAF010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.225"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            369..1000
                     /locus_tag="IVZ69_002833"
                     /pseudo
     CDS             369..1000
                     /locus_tag="IVZ69_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          343 a          181 c          182 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaata
      301 taggctctat aatttatggg actgatgaat caaaattgat tcttcagtcc cattgttatt
      361 ttaggtatat gattcgtaca ttgaaagagt tgaaaaacta tcttccgaag ccgtcaaaaa
      421 ggaccctgcc aaaagtattg atggtggatg aatttcgttc gcacgcttca attgtggata
      481 aaatgagctt tatttgtgcg gatggcgaga ctggaaaact cattgatatt ttgcctacac
      541 gaaaattgtc tcgattaaca cactatttta gtcgctgtgc aaatcctgaa gcggtggaat
      601 atttagtgac agatatgaac gccgcctact tccaactgac aaaacgtgtc ttaccaaatg
      661 cgaaagtcgt cattgattgt tttcatatca tcaaacattt gaatcaggcg ttcaatgatt
      721 ttcgtgtaca agaaatgaaa agattacacc agttagggca acgacgggaa gccgagaaag
      781 tgaaaaagaa ctggcgcttt cttctaaaaa accgtcaaaa aatcaatcac tatgattaca
      841 aaacatggcg cagttttcgt gcacctaaat acccactact cactgaagca atgatgattg
      901 atcgattgct ggcattttca acgcctttaa aggacgccta tacttttttc catgagctga
      961 ccgaagcctt tagagacaag gaatcagact tattttttac
//
LOCUS       DACDAF010000215          985 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.226, whole genome shotgun sequence.
ACCESSION   DACDAF010000215 DACDAF010000000
VERSION     DACDAF010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.226"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>985)
                     /locus_tag="IVZ69_002834"
     CDS             complement(<1..>985)
                     /locus_tag="IVZ69_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184826.1"
                     /translation="GNPNLLSKLSYDLIENQNTSAGTLSKGENSFKYNKISAEVEGGV
                     ELYYKRRGIANWLPSNKTLVMTVKLRAGADYSPVDGKLILIRYRYVDSGTGKIVLDLP
                     INSNSITQEWKEFSITGTTPTFSPQAYHPWIQFRAQDGILGEIEMSYDIKIEEGSTAT
                     PFQPNLLAEPYNMCREYPNENIADHTVKFPIESGDHQIYQGYTEEELMIGQTYTITLK
                     GTKPASQTFVAYNHWTARLGELKPVDGLTDVWSLTFTPTNVVASSPKLFRVYQYPQST
                     VGACRIDWLKIEKGDTRTPNISEYKYRGTGMRDSNNPKDYVWDLAPEYVED"
BASE COUNT          258 a          200 c          182 g          345 t
ORIGIN      
        1 ttatcttcga catattctgg tgctagatcc caaacataat cttttggatt gtttgaatca
       61 cgcataccag taccacgata tttatactca ctaatattcg gggttcgtgt gtcgcctttt
      121 tcaatcttga gccagtcgat ccggcatgcg cctactgttg attgtggata ctgataaaca
      181 cgaaaaagtt taggtgaact cgccacaaca ttcgttggtg tgaatgttag agaccatacg
      241 tctgtcaacc catcaactgg ctttagttct cctaaacgag cagtccaatg attatacgct
      301 acaaaggttt gacttgcggg ttttgttcct ttaagcgtga tagtatacgt ttgacctatc
      361 ataagctctt cttctgtgta accttgatat atttggtggt cgccagattc gattgggaac
      421 ttaactgtat gatcggcaat attttcgtta ggatattcgc gacacatgtt gtaaggttct
      481 gctaataagt taggttggaa tggtgtagct gttgagcctt cttcgatttt gatgtcatag
      541 ctcatttcta tttccccaag tatcccatct tgagccctaa attgtatcca aggatggtat
      601 gcttgtgggc taaatgttgg agtagttcca gtaatactaa actctttcca ttcctgagtt
      661 atcgaattac tgttaatagg taagtctaaa acaatcttgc cagttccact gtcaacatac
      721 ctatatctaa tcagtataag ttttccgtca actggactat agtccgctcc agctctaagc
      781 ttaacagtca ttacaagcgt tttattagat ggtagccagt tagctatacc tcttcgttta
      841 taatatagct ctactccacc ttccacttca gctgatatct tattatattt aaacgagttt
      901 tcacctttag aaagtgttcc agctgaagta ttttgatttt caattaagtc gtatgatagc
      961 ttacttaaca aattaggatt tccac
//
LOCUS       DACDAF010000216          943 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.228, whole genome shotgun sequence.
ACCESSION   DACDAF010000216 DACDAF010000000
VERSION     DACDAF010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.228"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..731
                     /locus_tag="IVZ69_002835"
     CDS             <1..731
                     /locus_tag="IVZ69_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HAP8184827.1"
                     /translation="KSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDYSTSQEILNN
                     SENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEESLESVSGIKY
                     IIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQFIFELIFISI
                     PSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQSYLILISII
                     VLSVVFASSLMLIKKPKEILSKIS"
     gene            741..>943
                     /locus_tag="IVZ69_002836"
     CDS             741..>943
                     /locus_tag="IVZ69_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8184828.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNE"
BASE COUNT          369 a           91 c          158 g          325 t
ORIGIN      
        1 taaaaagtca taaatttaaa attataggga tcttttctgg taaaaaacag gaaacatata
       61 caggattatc ttctgatttt agtgaaaata tggtgtttgt agattattca acaagccaag
      121 agatattaaa taattcagaa aataatgaaa ttgcaaataa aattttaatg tattctggta
      181 gtgcagaatc tacagactta gccttaaaca aattgaaaga gcttaaaatt gatgagtcaa
      241 agtattttgt tgaaaaagat tctaatgcgt ttgaagagtc tttagagtca gtgagtggaa
      301 taaaatatat aataaaagta atgacttatt ctattatgtt aggtgggatg gttgttcttt
      361 cattaatctt gattctatgg ttaagggaaa gaatttatga aataggtata ttcttatcta
      421 ttggaacatc taagatacaa attataatgc aatttatatt cgagttaata ttcatatcga
      481 taccaagtat aatatcttcc ttatttttag gaaatgtatt actaaaagta attgtagatg
      541 gattcattaa ctcagaggat tcaatgattt ccggtggaag tttaataaat aatagtagtt
      601 ttatgtcaaa tataacaaca cttggacaaa gttatttaat attaataagt attattgttt
      661 tatcagttgt atttgcttct tcattaatgt taatcaagaa gcctaaagaa atcttatcaa
      721 aaataagtta ggagaaaata atggatatat tagaaataaa gaatgtagca tatagttatg
      781 caaattctaa agaaaaagtt ttgtcaggag taaatcaaaa atttgaactt gggaagtttt
      841 atgcgatagt aggaaagtca ggaacaggaa aatctacact tctttcctta cttgctggac
      901 ttgataaacc tcaaacagga aaaatattgt ttaagaatga aga
//
LOCUS       DACDAF010000217          931 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.229, whole genome shotgun sequence.
ACCESSION   DACDAF010000217 DACDAF010000000
VERSION     DACDAF010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..931
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.229"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..707)
                     /locus_tag="IVZ69_002837"
     CDS             complement(<1..707)
                     /locus_tag="IVZ69_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HAP8184829.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGE"
BASE COUNT          311 a          156 c           75 g          389 t
ORIGIN      
        1 tcttctccaa aatttgttcc tatttcttct tcactatctt caagtaagta tataaaatca
       61 caatattcat ctataattcc agaatctcca aaatcaatta ttccagttaa tctattattg
      121 ccatctaaca atagatgatt acaactaaaa tcattatggc ataaacactt tttaccctca
      181 aaaactgttg ttgcatttag tctttccata aaactttcta tataatcttt ttctatatca
      241 gttaaatcat tataaatagt ttcacgcaac aatatatact cttctaatac attttgttta
      301 ttatcaatag tacattcact aatatctgta taatctaaac cgtgcatttg tcttaaaaaa
      361 ctggcaatat ctcgttttaa caaattttgt tcttcttctg acatagtaga ataaatttct
      421 ggtgttaaaa aagttccttt aatttcttta taacctagta tagataattc atcactaata
      481 tacgaatatt caatattagg aatttttaca ttagtttcta aatttgtatt taaaaaatta
      541 tatattgctt tttcttttgc ataacctttt ttcttattag tactaaattt tgttttaaaa
      601 atgtattcat tattaactaa atatgccaca ctatcataac cactaccgat tatttcaata
      661 ctatctactt tgaaattatc aaagtaatgc tcaattaaat atttcattgc cttaacattt
      721 gtggcattat catcatatct atattccatt aaataacaat cttctttttt gccctcgtgt
      781 aattcatgtt ctggcaaatc ttcaataatt ctaaaaccag atttttggta tgcccttatt
      841 gctcttggat tatttttatg agggtctaaa ataactgcat tagcatttct ttcttttttc
      901 aaaaattcaa aaatcaattt aatatatctt g
//
LOCUS       DACDAF010000218          926 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.230, whole genome shotgun sequence.
ACCESSION   DACDAF010000218 DACDAF010000000
VERSION     DACDAF010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.230"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            4..>926
                     /locus_tag="IVZ69_002838"
     CDS             4..>926
                     /locus_tag="IVZ69_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase family protein"
                     /protein_id="HAP8184830.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTITPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSH"
BASE COUNT          320 a          125 c          167 g          314 t
ORIGIN      
        1 actatgtgta cgtctattac ttatgtaaca agtgatcatt attttggaag gaattttgat
       61 tatgaaatat cttacaatga agtagtcact attactccaa gaaattataa gttgaatttt
      121 cgaaaggtaa atgatttgga tactcattat gcaatgattg gtattgccgc tggtatagct
      181 gactaccctc tttattacga tgcgacaaat gaaaaaggat tgagtatggc tggactaaat
      241 ttttctgggt atgctgatta taaagaaata caagaaggga aagacaatgt atctcctttt
      301 gaatttattc cttggatttt aggacaatgc tcaacagtag gagaagctaa aaaattgtta
      361 aaaaatatca atttagcaaa tataaattat agtgacgaac ttcctttatc ccctttacat
      421 tggctattag ctgataaaga aaaatcaatt gtcattgaaa gtatgaaaga tggacttcat
      481 atatatgata accctgtggg cgttcttacc aataatcctt catttgacta tcaattattt
      541 aatttaaaca attatcgtgt cttatcgagt gaaactccta aaaataattt ttcaaatcaa
      601 ataagtttga atgcctatag ccgcggtatg ggagggatag gcttgcctgg agatttatcc
      661 tcagtatctc gttttgttaa agcgactttt acgaagctga attctgtatc tggagattca
      721 gagtcagaaa gtattagtca atttttccat atcttaggtt cagtagaaca acaaaaaggt
      781 ttgtgtgatg ttggtgatgg aaaatatgaa tatacaattt attcttcttg ttgcaatgtt
      841 gacaaaggaa tctattatta tcgaacatat gaagacagtc aaattactgc aattgatatg
      901 aataaagaag acttagatag tcataa
//
LOCUS       DACDAF010000219          921 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.231, whole genome shotgun sequence.
ACCESSION   DACDAF010000219 DACDAF010000000
VERSION     DACDAF010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 921)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 921)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..921
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.231"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..461
                     /locus_tag="IVZ69_002839"
     CDS             <1..461
                     /locus_tag="IVZ69_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HAP8184831.1"
                     /translation="DLDALQVVSVVSFYESFIDGADPLDMQGYLQTQLTTEILAVELA
                     QSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLGQRLLDEANRYAKT
                     KQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPILEKEI"
     gene            complement(444..>921)
                     /locus_tag="IVZ69_002840"
     CDS             complement(444..>921)
                     /locus_tag="IVZ69_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184832.1"
                     /translation="DPAIVIPQYFAQLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQ
                     YEAQFLPILDQVIKNKLAFELNAKSAYLYDNLALYEYVIDLYLSRGGTLFSVGSDGHY
                     LEHFRFHFDDLFALLKAKGVTELAIYQKGKRIMVPLPVQKNVLSIKSEDVFLDFFF"
BASE COUNT          329 a          156 c          163 g          273 t
ORIGIN      
        1 atgatctaga tgctttacaa gttgtaagtg ttgtcagttt ttatgaatcg tttatcgatg
       61 gcgcagatcc acttgatatg caaggatatt tacagacaca attgacaact gaaatattgg
      121 cagtagaatt ggcacagtca accagtaaat ttattggtat taaggatcat caaatactca
      181 ttggttatat gaaagtcaat gatgaaaaag atgctataga gattcaacgg ctctatctgc
      241 tcaaagatta tcaaaacaaa gggttagggc aacggttact cgatgaagcg aatcgttatg
      301 ctaaaacgaa acaaaaacgt tatttacgtt tgactgttta tgaaaaaaat catgcaggta
      361 ttcgttttta tgaacgtcat ggatttaaaa aaatcgggat caaacatttt cctttaggaa
      421 aacaagatcg tatttgtccg attttagaaa aagaaatcta aaaaaacgtc ctcacttttg
      481 atgctgagga cgtttttttg gactggtaat ggaaccataa ttcgctttcc tttttgataa
      541 atcgctaatt ccgtcacacc ttttgctttt aacagagcaa aaagatcatc gaaatggaaa
      601 cggaaatgtt caaggtaatg cccatctgat ccaacactaa acaaggtacc accacgtgaa
      661 agatataaat cgatgacata ttcatataac gctaaattgt catacaagta agcgctctta
      721 gcatttaatt cgaatgccaa tttattttta attacttgat ctagaatcgg taaaaactgc
      781 gcttcatatt gtttaaattc agcaacggat agaccaaata cccgaaaacc atagtcaaaa
      841 tgagcaaaga catctgcttc tataacaact agtgcttctg aaagttgtgc aaaatactga
      901 ggaatcacaa tagcaggatc c
//
LOCUS       DACDAF010000220          892 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.232, whole genome shotgun sequence.
ACCESSION   DACDAF010000220 DACDAF010000000
VERSION     DACDAF010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..892
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.232"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            149..841
                     /locus_tag="IVZ69_002841"
     CDS             149..841
                     /locus_tag="IVZ69_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HAP8184833.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAKLSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
BASE COUNT          394 a          131 c          154 g          213 t
ORIGIN      
        1 attttttaaa tagataaaaa aggaggatta aatgagtatt tgatagtatt tatattaaaa
       61 ttacatatgt aatttaaaaa cgcttgacat tgtgtttgag atcacttact tttagcatgt
      121 aaaagtattg gattaaggag ctatgcaaat gaaaaagaaa tttattactg gtgggattgt
      181 cgttgcattt ctatgtctaa ttggctacac aggcacgcgg tacgcaaatg aaattatttt
      241 gtggggtgga gagacagata ttgatacaat caatgagaat ctgacacagc ttgatcatac
      301 attgacagat aaagagcaag cgattacaga tcttaccgct cgactagcac aaaaagaaca
      361 gacattgcaa gattcaaagg cagatgtcca agaataccaa acaaaagtaa atgaattaga
      421 aaaccaaaaa aatcaatcgg cagcagaaaa acaaaactta gaaagtcaat tagtcagcaa
      481 ggatgcacaa ctacaaagca aacaaaatga aatcaatgtc aaactagatg agatcaacca
      541 aaaaaatgat gaaatcaatc atctgaatgc agattggaca gcaagactac aagaagcaca
      601 agcaaaactt tcagaattac aaaatactgt aaatggtttg aatcaacaaa tcgcaacact
      661 gacacaagaa aaaacaaatg tagaaactca gttaacagat acacaaaaga aattagacga
      721 agcaactgct gaaaactcaa gcttgaaaca atatattcaa aagttagaaa aagcaaaaga
      781 tgaagtggaa gatacagctg ataaatctca gcaaattgtt gaagaacatt tgcgtaaata
      841 atctttctta acaagtaaac ctaaattagt aaagaagcaa cagtaatcta ta
//
LOCUS       DACDAF010000221          890 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.233, whole genome shotgun sequence.
ACCESSION   DACDAF010000221 DACDAF010000000
VERSION     DACDAF010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 890)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 890)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..890
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.233"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..888
                     /locus_tag="IVZ69_002842"
     CDS             <1..888
                     /locus_tag="IVZ69_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HAP8184834.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
BASE COUNT          386 a          116 c          144 g          244 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt
//
LOCUS       DACDAF010000222          866 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.234, whole genome shotgun sequence.
ACCESSION   DACDAF010000222 DACDAF010000000
VERSION     DACDAF010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.234"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            74..835
                     /locus_tag="IVZ69_002843"
     CDS             74..835
                     /locus_tag="IVZ69_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HAP8184835.1"
                     /translation="MHTPEEIMELSIHLGTKKIHKPILAKLILGFIGGAMISLGYLAY
                     VRVSASIPESMASLTSLVGASVFPIGLLVILLGGGELITGNMMAVAIAFMDKKVTFSQ
                     LVKNWSVITFANIIGAIFVAYFFGHFVGLTHSGVYLDQVIHIADHKIAVSWWQALGSG
                     IGCNWFVGLALWLSYGAKDAAGKVLTIWFPVMIFVAIGFQHSVANCFVIPAAIFEGQA
                     TWLEFLSNFIPVYIGNIIGGAIFVSGFYYVSYKHH"
BASE COUNT          227 a          147 c          184 g          308 t
ORIGIN      
        1 caaagaaaat gtgatttttt tcactatatt ttatcacatg aaaattcatt aagaaagtag
       61 gaatcgaagt attatgcaca caccagaaga aattatggaa ctcagtattc atcttggaac
      121 aaaaaaaata cataaaccta tcttagctaa actgatttta ggttttatcg gaggagccat
      181 gatttctcta ggttatttgg catacgtacg agtctctgct tctatcccag aatctatggc
      241 tagcttgact agtttagttg gtgcctcggt ttttcctatc ggcctgctgg tcatccttct
      301 tggcggtggt gaattgatca ccggaaatat gatggctgtg gcgattgcct ttatggataa
      361 aaaagtcaca ttctcacagc tggttaagaa ttggtcagtg attacttttg caaatattat
      421 tggtgcaatt ttcgttgcct atttctttgg acactttgtt ggtttaactc attcaggtgt
      481 ctatctcgac caagtgattc atattgctga tcataaaatc gctgtttctt ggtggcaagc
      541 attaggctcc ggaataggtt gtaattggtt tgtcggttta gcgttatggt tatcatatgg
      601 agcaaaagat gcggccggca aagtactaac gatttggttt ccagtcatga tttttgtggc
      661 aatcggtttc cagcatagtg tggccaactg ttttgtgata cctgctgcca tatttgaagg
      721 tcaagcgact tggttagaat ttctctcgaa ttttatcccc gtttatattg gaaatatcat
      781 cggcggagct atttttgttt caggttttta ttacgttagt tataagcatc attaagattg
      841 aaggtaatgt tcattcgagc attacc
//
LOCUS       DACDAF010000223          791 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.235, whole genome shotgun sequence.
ACCESSION   DACDAF010000223 DACDAF010000000
VERSION     DACDAF010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.235"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..780
                     /locus_tag="IVZ69_002844"
     CDS             <1..780
                     /locus_tag="IVZ69_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8184836.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          338 a          107 c          102 g          244 t
ORIGIN      
        1 gatatgctag attactacta ttttgaaaaa aatttatcat ataattatgt aatacattta
       61 aaaactttta caggaatgat ttttaaattc gccaaccgtc gatatggatt aaaatataat
      121 cccgtaaatg gggtttcttt agcaagaaaa cctaagacaa acgaagaaat aaaaaaagaa
      181 aaagatggtt atttatcaaa agaagaagtt caaatgattg ctagtaaaca aaaaagttca
      241 catcaacagt cacgttattc tttaattact aaatttttgt ttttaactgg actacgttat
      301 ggtgaattga tatctttgac tgaatctgat tatgatggta ataaaattac ggtttctggt
      361 acttatgatt acgagttaaa aattaaaaca acaactaaaa atacaggttc ttatagaacc
      421 attgaattat caagtaatgc taaagaaatc atagatcaat taattgaaga aaacaaatta
      481 attaagaata ataaagataa atacattttc atctctaaaa atggtaaccc gatatctatt
      541 caagcatata atcaatcttt aagagcagta tccaaagaat taaacataga taaaaaagtt
      601 tcttctcaca tgttaaggca ttcccacatt tctctactta cagaattagg aatcccatta
      661 aaagccatta tggatcgtgt aggacatgaa gattcaaaaa caacattaaa gatttatact
      721 catacaacta aaaatatgca aaatcaacta gtagaaaaac taggaaaaat agaaatttaa
      781 attgcccctt t
//
LOCUS       DACDAF010000224          768 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.236, whole genome shotgun sequence.
ACCESSION   DACDAF010000224 DACDAF010000000
VERSION     DACDAF010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..768
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.236"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(248..601)
                     /gene="tnpB"
                     /locus_tag="IVZ69_002845"
     CDS             complement(248..601)
                     /gene="tnpB"
                     /locus_tag="IVZ69_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HAP8184837.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          222 a          156 c          135 g          255 t
ORIGIN      
        1 cgtccaaata atttgttggt taaataattg accttttcat tcaatagttg gatttcagtt
       61 gtaagattct gaatggtttg ttgttgtgct tgattggttt tatgggcttc ttgaagcaac
      121 tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa ctgattttgt
      181 tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt tgtgttaacc
      241 ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga tcgatactta
      301 atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg tctttcgtcc
      361 gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa ccatcaccgt
      421 cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa acggcatctt
      481 cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca attccttttc
      541 gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa tcataaagca
      601 ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc gttatagatc
      661 aaaacttcag aaccattctc tcttttgatg cgcatcgcta acttggcagc cgcgggttta
      721 cctttttctg gtgcactctt ttcgtttcct aattggacag gaacaatc
//
LOCUS       DACDAF010000225          766 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.237, whole genome shotgun sequence.
ACCESSION   DACDAF010000225 DACDAF010000000
VERSION     DACDAF010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 766)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 766)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..766
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.237"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(109..>766)
                     /locus_tag="IVZ69_002846"
     CDS             complement(109..>766)
                     /locus_tag="IVZ69_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element ISEfa8 family transposase"
                     /protein_id="HAP8184838.1"
                     /translation="IGRIMKRRGLTSTYTIAHFKGQRTACNEAKTANVLDRTFTQEQP
                     LEAIVTDLTYVRVGKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTD
                     VKLFHTDRGKEFDNQTIHEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQ
                     FETLAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA
                     "
BASE COUNT          213 a          175 c          146 g          232 t
ORIGIN      
        1 gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gctacgattg cccttgacaa
       61 tgagcatcct cggatctgat tttctccggc agaagcacaa tcattcaatt acgctgcctc
      121 tccagaggta tcagatccgc gctcattatc aaggattcgc ttcgccaatc tctgttgtcg
      181 aatttggatc ggtgtttcat acgccaacgt gccatgtaag cgtagatagt tccaccaatg
      241 cacataatca aacaattcta gacgtagctg tgccagtgtc tcaaattggt attgatgcac
      301 gaattctact ttgacagatt tataggttga ttccacaacg gcattatcat acggacaacc
      361 cttcctactc aatgaacgag taattccaaa accattcaga atctcatgaa tggtttggtt
      421 atcaaattcc tttccccggt ctgtatgaaa aagcttgacg tctgttaaag aatacggtat
      481 ccgtccaaag gcttctttta ccaatgaggc atctttcttc tcaccacagg aataaccaat
      541 aatttctcga ttaaacaaat caagtattaa gcagatataa tgccactttt tccccacgcg
      601 aacataagta agatccgtaa cgatggcttc caatggctgt tcttgtgtaa aggtccgatc
      661 taatacattc gctgttttcg cttcattaca agctgttcgt tgccctttaa aatgagcgat
      721 cgtataggta gatgtcaatc cgcggcgttt catgattcga ccgatt
//
LOCUS       DACDAF010000226          765 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.238, whole genome shotgun sequence.
ACCESSION   DACDAF010000226 DACDAF010000000
VERSION     DACDAF010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.238"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(597..740)
                     /locus_tag="IVZ69_002847"
     CDS             complement(597..740)
                     /locus_tag="IVZ69_002847"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184839.1"
                     /translation="MEKEAFDLHVLGTPPAFVLSQDQTLIKSSNNLAIVKLNLFASIL
                     LAC"
     gene            659..>765
                     /locus_tag="IVZ69_002848"
     rRNA            659..>765
                     /locus_tag="IVZ69_002848"
                     /product="16S ribosomal RNA"
BASE COUNT          315 a          124 c          134 g          192 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactctc gatgaagtag acctttgaaa actgaacaaa
      541 gtaagacaaa ccaaatgtgt agggcgtctt gattcaattc aagacaacaa acatttttaa
      601 caagcaagca atatgctagc aaacaaattg agcttaacaa tcgcaagatt gttcgaactt
      661 tttatgagag tttgatcctg gctcaggacg aacgctggcg gcgtgcctaa tacatgcaag
      721 tcgaacgctt ctttttccac cggagcttgc tccaccggaa aaaga
//
LOCUS       DACDAF010000227          713 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.239, whole genome shotgun sequence.
ACCESSION   DACDAF010000227 DACDAF010000000
VERSION     DACDAF010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..713
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.239"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..448)
                     /locus_tag="IVZ69_002849"
     CDS             complement(<1..448)
                     /locus_tag="IVZ69_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M protein trans-acting positive regulator"
                     /protein_id="HAP8184840.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT          216 a          123 c           95 g          279 t
ORIGIN      
        1 tcaactttct cttttcaaaa aaaatttgat atttttttag atttcttttt agtctttgta
       61 atactttata agccacagaa taactcacgt gatgctgttt agcaaaattt tctactgaga
      121 tatatttttc ctgaaagaaa gccaatacca ttttcataga taaagaatcc gttatataac
      181 gagataacag agctttgcta gaacattttc cattaatttc cagacatata tccaattcac
      241 tgacggttac tcgcaaattt ttctctagat cgaacttttg taaatcatgt ttcagcttat
      301 cgatcgtttt tttcaagaga aatgtcgata gcgacaactc ttcttgaaca ttcgatattg
      361 actctgataa atttgagctt gcttctaaat atttaagtaa tgaataactt ctgtgatctt
      421 ctttgcttaa aaaaaactca taattcatta gtcatcagct ctttctacgt atattacttt
      481 ccatgcattc accaactagc tggggataaa actgatttcc tggatccgag tcactgttgt
      541 cagcgattct tgtttgtata atatacatcg tcctgtcttt tttttaacat tttggagagc
      601 gttttatttg gcctttctcg cgatcaaacc tgttattaga attatatcat ttactagtat
      661 gcatttttat taataaaatg gtatatttta tattgttata aaaagagccc aac
//
LOCUS       DACDAF010000228          696 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.240, whole genome shotgun sequence.
ACCESSION   DACDAF010000228 DACDAF010000000
VERSION     DACDAF010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.240"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(53..628)
                     /locus_tag="IVZ69_002850"
     CDS             complement(53..628)
                     /locus_tag="IVZ69_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HAP8184841.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
BASE COUNT          229 a          151 c          125 g          191 t
ORIGIN      
        1 atgaaaaaac agagccagat tagcattatt ttgctaatcc agctctgttt attcagccta
       61 tttttctttt tgaatatatc aagcgttggg gcaacatagt gatgactaat gaaacaacga
      121 cgatagacaa caagcgatca aggtagtctg tacccgcctg taccaagatc acacttgttg
      181 tctgacttaa acctaaccca tgtaatagct gaacgatcat actggatcct gaggaggtga
      241 tcccgccaaa taactgaacg gtaatgatcg aagaaacgat cgttccaggt accgacaaaa
      301 tcaaagcgag taataacagt ttcaagctgt ttttatcttt gccgagatat cttggcaaaa
      361 tcaatccagc aagcaagcct gtgagaattt ggattggcga ataatacaga gaaaaaatat
      421 ctgtagtcac tccacttaaa ataccgctgg acaatcctgt cagcattcca ggtacaggcc
      481 caagcaatgc accagcaaaa atcgttccga tagaatcgag atagattggc aaacgaagcc
      541 ataaagcaat cgttcctcca atataattga tcccaataca caaagccatc actgtaagta
      601 cgcgagttgc cattttgttt ttattcattt tgttagccca tctttaacct ttccaaatct
      661 ttcataatcg tttcttcttg tgcatttaaa agaacg
//
LOCUS       DACDAF010000229          682 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.241, whole genome shotgun sequence.
ACCESSION   DACDAF010000229 DACDAF010000000
VERSION     DACDAF010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.241"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..652
                     /locus_tag="IVZ69_002851"
     CDS             <1..652
                     /locus_tag="IVZ69_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HAP8184842.1"
                     /translation="QDVIIVAVGYYLRYNLSYREVQEILYDRGINVSHTTIYRWVQEY
                     GKLLYQIWKKKNKKSFYSWKMDETYIKIKGKWHYLYRAIDADGLTLDIWLRKKRDTQA
                     AYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQGTEHRTIKYLNNLIEQDH
                     RPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKVLLGIPA"
BASE COUNT          232 a          120 c          136 g          194 t
ORIGIN      
        1 gcaggatgtg attattgtag ccgtgggcta ctatcttcgt tataacctta gctatcgtga
       61 agttcaagaa atcttatatg atcgtggcat taacgtttct catacgacga tttatcgttg
      121 ggtgcaagaa tatggcaaac tactctatca aatttggaaa aagaaaaata aaaaatcctt
      181 ttattcatgg aaaatggatg aaacgtacat caaaattaaa ggaaaatggc attatttgta
      241 tcgagccatc gatgcagatg gtttaacctt ggatatttgg ttacgtaaaa aacgggacac
      301 acaagcagcc tatgcttttc ttaagcggtt agtgaagcag tttgatgaac cgaaggttgt
      361 agtcacagat aaagccccct ctattacaag tgcctttaag aaactaaaag aatacggctt
      421 ttatcaaggg acagaacatc gtaccattaa atacctgaat aatttgattg aacaagacca
      481 tcgtccagta aagagacgca ataaattcta tcgaagttta cgcactgcct ctaccacgat
      541 taaaggcatg gaagccattc gaggattata taagaaaacc cgaaaagaag gcactctctt
      601 cgggttttcg gtctgtactg aaatcaaggt attattggga atcccagctt aaatcataga
      661 taccgtaagg gattttattc tt
//
LOCUS       DACDAF010000230          673 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.242, whole genome shotgun sequence.
ACCESSION   DACDAF010000230 DACDAF010000000
VERSION     DACDAF010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..673
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.242"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(31..252)
                     /locus_tag="IVZ69_002852"
     CDS             complement(31..252)
                     /locus_tag="IVZ69_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184843.1"
                     /translation="MEEEKIFEKRWELASVEQRARYHNLMSSYRNIDWTYKEKKYLLW
                     LCQLDVNTFETFEVILDKIKNSNEKRADL"
     gene            complement(350..595)
                     /locus_tag="IVZ69_002853"
     CDS             complement(350..595)
                     /locus_tag="IVZ69_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184844.1"
                     /translation="MDFPEVVKEVQEIGATISDSRSSPMNYQDAHGIKIIDQERNVRK
                     YTTINECVINENLCRAPITKHIKNRSKAKDGRTFTTF"
BASE COUNT          205 a          132 c           91 g          245 t
ORIGIN      
        1 aagagttaat aaaataaaaa gagcgaacca ttatagatca gctctttttt cattgctgtt
       61 tttaatctta tctagaatca cttcaaatgt ttcaaaggta tttacatcta actgacataa
      121 ccaaagcaag tacttctttt ctttgtaagt ccaatcaata ttacggtaag aggacattag
      181 attatggtac cttgctcttt gttcaactga agccaattcc cagcgttttt caaatatttt
      241 ttcttcttcc attattgatc cctcgcaaga cgctacctca aacttaaata atgggcagcg
      301 aaagtctaat tccttagatc taagtatagc aaacaaatat gaaaaaaact tagaaggtag
      361 taaaagttct tccgtctttt gctttgcttc tattcttaat gtgtttcgtt atcggtgccc
      421 tacaaagatt ttcattaatt acacactcat ttattgttgt gtattttctg acatttctct
      481 cttgatcaat tattttaatt ccatgggcat cctgatagtt cataggagag gagcggctat
      541 cagaaatagt tgcacctatc tcttgaactt cttttacaac ttctggaaaa tccatccatc
      601 ctgcttcagc tgtcaaaagt aataatctat aatatttatc tttccttttc aatctaagaa
      661 atcgtcaccc cat
//
LOCUS       DACDAF010000231          650 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.243, whole genome shotgun sequence.
ACCESSION   DACDAF010000231 DACDAF010000000
VERSION     DACDAF010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.243"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            1..271
                     /locus_tag="IVZ69_002854"
                     /pseudo
     CDS             1..271
                     /locus_tag="IVZ69_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            347..>650
                     /locus_tag="IVZ69_002855"
     CDS             347..>650
                     /locus_tag="IVZ69_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP8184845.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGY"
BASE COUNT          201 a          118 c          124 g          207 t
ORIGIN      
        1 ctatactgtt gcttatttta aagtacatca ttctacttgc aatgaagcca aaacgacaaa
       61 cgtattgaat cgtaaattct taagagacaa cccattagaa gcgatcgtaa cagacttgac
      121 ttatgtacga gtcgggaaaa aatggaatta tgtctgtttc attttggatc tgttcaatcg
      181 agaaattctc ggctattctt gtggagaaca taaagatgcc gttctagtaa aaaaagcatt
      241 tagccgtatc aaacaacctc tgacagaggt tgacagactg tagacaaagt ccattttatg
      301 gatgatgtct acagtctttt cttttataat agatttatga aaacgaatgc aaggagtgat
      361 agctatgatg tctaaaaaca atacgaatgg tagaaatcaa tttgcgatgc ttacgattga
      421 tgatctagtt cctcaagatc atctcgttcg aaagattgat gccgcgcttg attttgaatt
      481 tatttatcca atcgtcgaag ccacttactc cgatttaggt cgcccaagta tcgatccagt
      541 gattctgatc aaattggtgt ttattcagta tttattcggt atccgttcca tgcgacaaac
      601 cattaaggaa gtcgatacca atgtcgctta ccgctggttt ttaggctact
//
LOCUS       DACDAF010000232          640 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.244, whole genome shotgun sequence.
ACCESSION   DACDAF010000232 DACDAF010000000
VERSION     DACDAF010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.244"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..283
                     /locus_tag="IVZ69_002856"
     CDS             <1..283
                     /locus_tag="IVZ69_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HAP8184846.1"
                     /translation="LIQDDLHHTHRLWLMNKINLYFGHSYVFAFYDYRTNITEVDLVI
                     SNYYIDTGKTPLLLMKNIPTERNWRLFEKTIYQLKKEKEVVKSAFCPEY"
BASE COUNT          218 a           89 c          119 g          214 t
ORIGIN      
        1 tttaatacaa gatgatttac accatacgca tcggttatgg ttaatgaata aaattaatct
       61 gtattttggg cattcttatg tttttgcttt ttatgattac aggacaaata taactgaagt
      121 agatttggtt atttctaatt actacatcga cactggaaaa acgccattac tgttaatgaa
      181 aaatatacct accgaaagaa actggcgttt gttcgagaaa acgatttatc aattgaaaaa
      241 agaaaaagag gttgtgaaat cagcgttttg tcctgagtat tagagaaaca aacggaaaaa
      301 tagtttttca tattttgccg tttttgagct aataccgagg gacagctgat tgaacaccat
      361 ttattgagag attgtgaaaa aactgtcctg catcaagtaa taagaacagc caagtaaaaa
      421 cagcttctca tgtttgttga atattgtgac ttgtgaccga ggagttggca agagaacacc
      481 gtttattcgg aaaaagggac tgtgacacta catgtcacag tccctttttg attgaattat
      541 ctcatttgtt ttctaatttt ttctttattt gagaaaatag ttgaactgga taaaaagtac
      601 tggacgtgtc aaaattattt tggatcaaat tagatctatt
//
LOCUS       DACDAF010000233          635 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.245, whole genome shotgun sequence.
ACCESSION   DACDAF010000233 DACDAF010000000
VERSION     DACDAF010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.245"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            5..622
                     /locus_tag="IVZ69_002857"
     CDS             5..622
                     /locus_tag="IVZ69_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184847.1"
                     /translation="MGFQVLFGSLILTIVFLKWKTSNKKSMWSLVGIVLIIFTVTAAT
                     EANYSHKIQSYKGRLVMTKKDVTRYTSSRTGGLYDYAPLDALKYKDHLKKHEVKVGDR
                     WENASHKAYNSKIVYTVEDADEQNITLPVFNYWGTVVKVNGKKSTIENDNGLVSIKGT
                     GKRTIVEVSSTYPTTMILSLLISSITFIFLFTRYLIRCCGEMKID"
BASE COUNT          234 a           83 c          119 g          199 t
ORIGIN      
        1 aaccttgggt tttcaagtgc tttttggttc attaatctta accatagtgt ttttaaagtg
       61 gaaaacaagc aacaaaaaaa gtatgtggag ccttgtagga atagttctta ttatttttac
      121 tgtgactgca gcaacagaag caaattattc gcataaaatt cagtcgtata aaggtcgttt
      181 agttatgacc aaaaaagatg ttacacgtta tacatcctca agaactggag gcctatatga
      241 ctatgcacca ttagatgcat tgaaatataa agatcattta aagaaacatg aagtaaaagt
      301 tggtgatcgg tgggagaatg catctcataa agcatataat tccaaaatag tctatacagt
      361 agaagatgcc gatgagcaaa atatcacatt acctgtattc aattattggg gaacagttgt
      421 gaaagtaaat gggaaaaaga gcactataga aaatgacaat ggtttagtgt ctattaaagg
      481 tacggggaaa agaactatag ttgaggtttc atctacgtat ccaactacga tgattctatc
      541 tttattaatt agttcaataa cttttatatt cttatttaca cgttatttaa taagatgctg
      601 cggtgaaatg aaaatagatt agatagatat tataa
//
LOCUS       DACDAF010000234          631 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.246, whole genome shotgun sequence.
ACCESSION   DACDAF010000234 DACDAF010000000
VERSION     DACDAF010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.246"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..355
                     /locus_tag="IVZ69_002858"
     CDS             <1..355
                     /locus_tag="IVZ69_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184848.1"
                     /translation="GAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETNMTRDELL
                     RKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTTSQIKQDT
                     EDSLRKGWGMNNKVR"
BASE COUNT          243 a           72 c          130 g          186 t
ORIGIN      
        1 tggcgcacca atcagaaagt ttgataaggt ttattccacc aagcatcctt taaaactgtc
       61 gactttgtta aatgcgactt ccagagtttt agtagaaaag tatgagacta atatgacaag
      121 agatgaattg cttagaaaag ctttagatga gtatattaaa cagaatctta cgcaagaaga
      181 taagcaagat ttgtttaatg acgtggtgaa agaactagac ttgttcagag aaaaatatcc
      241 aattgttcca gaattagatg atcgtggaga aataataaga actaccagtc agataaaaca
      301 agataccgaa gactcactgc gcaaagggtg gggaatgaat aataaagtta gataataatc
      361 aaagaagaac taagtaacta cctttaaacg gtagttactt agttcttctt tgatttgcat
      421 gaaatagagg ggatttattt ttctggttac gtgattaaaa aatccaaaaa atgagcatag
      481 gaacggttat gattttaggg tgtgttttaa tgagatattg tgatttcatt aacaagtgta
      541 tgataatctg ttgttgagtt agtaaataag taatagagct aactctaaaa taaaactatt
      601 aggaggagat gtaggtgaaa aagtttaaaa a
//
LOCUS       DACDAF010000235          556 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.247, whole genome shotgun sequence.
ACCESSION   DACDAF010000235 DACDAF010000000
VERSION     DACDAF010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.247"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..>556
                     /locus_tag="IVZ69_002859"
     rRNA            <1..>556
                     /locus_tag="IVZ69_002859"
                     /product="16S ribosomal RNA"
BASE COUNT          135 a          130 c          168 g          123 t
ORIGIN      
        1 catgtgtagc ggtgaaatgc gtagatatat ggaggaacac cagtggcgaa ggcggctctc
       61 tggtctgtaa ctgacgctga ggctcgaaag cgtggggagc aaacaggatt agataccctg
      121 gtagtccacg ccgtaaacga tgagtgctaa gtgttggagg gtttccgccc ttcagtgctg
      181 cagctaacgc attaagcact ccgcctgggg agtacgaccg caaggttgaa actcaaagga
      241 attgacgggg gcccgcacaa gcggtggagc atgtggttta attcgaagca acgcgaagaa
      301 ccttaccagg tcttgacatc ctttgaccac tctagagata gagcttcccc ttcgggggca
      361 aagtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt gagatgttgg gttaagtccc
      421 gcaacgagcg caacccttat tgttagttgc catcattcag ttgggcactc tagcaagact
      481 gccggtgaca aaccggagga aggtggggat gacgtcaaat catcatgccc cttatgacct
      541 gggctacaca cgtgct
//
LOCUS       DACDAF010000236          524 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.248, whole genome shotgun sequence.
ACCESSION   DACDAF010000236 DACDAF010000000
VERSION     DACDAF010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..524
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.248"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(152..346)
                     /locus_tag="IVZ69_002860"
     CDS             complement(152..346)
                     /locus_tag="IVZ69_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184849.1"
                     /translation="MVHSTIGVVVEKSRDNLVFVTEIQTGRSFVVTDKAAKAYQSSDI
                     LTLNLTTKTFVDATEDYPFV"
BASE COUNT          163 a          110 c           79 g          172 t
ORIGIN      
        1 tgtgatagag aaataacaat ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat
       61 ttgattttga tcgggtctag tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc
      121 ttaaatttca tcttgactta tcaccattag actaaacaaa tggataatct tctgtcgcat
      181 cgacgaacgt cttcgtagtc agatttaacg ttaaaatatc gctactttga taagcttttg
      241 ccgctttgtc tgtgacgaca aaagatctgc ctgtttgaat ttctgtcaca aaaacgagat
      301 tgtctctgct tttttcaaca acaactccaa tcgttgaatg aaccatttct gcttcctccc
      361 ttctctttct tttgatataa tgtagtcgca aatcgcacca ctcaatgagt tggcggaaaa
      421 caattcattg aaaaaaagag tcctggacaa tcacgttcag gactctttta cttcttttat
      481 tcacttaaca actaacactc tgtgagtgaa atggactctt caat
//
LOCUS       DACDAF010000237          490 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.249, whole genome shotgun sequence.
ACCESSION   DACDAF010000237 DACDAF010000000
VERSION     DACDAF010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.249"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            143..400
                     /locus_tag="IVZ69_002861"
     CDS             143..400
                     /locus_tag="IVZ69_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184850.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
BASE COUNT          210 a           63 c           69 g          148 t
ORIGIN      
        1 ttttctgtcc acgttcatat tactccaaag ttttcctcat tccaaaagaa aagcacagaa
       61 tacacaaaga agcgttttta tttgtataaa ctatatcaaa gttctatact taaattatca
      121 aataaaaagg acgtgaagat aaatgtcaaa tttagaaaac aaagaagaaa aagttgtaaa
      181 caaaattgtt tctgttgtca ataaactgga taaagagtta gacgaacttg atacgttatc
      241 tgaaaatcca gaaaaaaaac ataacctaaa aaaatggtta gttgaacgaa aggctattca
      301 tgaaattaaa aaagttcttc atgaagctga taaatatgaa aaatatgatg aaaaagaact
      361 tgataaagaa tttaaagaaa tcaatgactt gttactataa ttgatttata cgactcattt
      421 ttgagtcgtc agactgcaaa caacactcta aatttaggag tttgtctaca gtctgaataa
      481 attttaaatt
//
LOCUS       DACDAF010000238          469 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.250, whole genome shotgun sequence.
ACCESSION   DACDAF010000238 DACDAF010000000
VERSION     DACDAF010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.250"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>469)
                     /locus_tag="IVZ69_002862"
     CDS             complement(<1..>469)
                     /locus_tag="IVZ69_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-1,6-N-acetylglucosaminyltransferase"
                     /protein_id="HAP8184851.1"
                     /translation="YQKHDYPRINRNNTTAFKIFRAIINRCLRMIKLPPKIRHHKFDL
                     YHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVI
                     GGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRK"
BASE COUNT          149 a           67 c           64 g          189 t
ORIGIN      
        1 cttttcttac aaataatttt tcactttctt ttatttgatc tatatccctt tcatcaaacc
       61 atttgttcat ggaaggatca ataatatgaa tatttgctaa tttcgaagtt tgtaaagtag
      121 tttcttcaat atttttcaat tcaagtggta aatctggtcc tccaataaca tttttatttt
      181 tgaacgagga attaaaaaaa agtgtatgaa aaaatttttc atctggggca aacataccta
      241 ttttaaaatt caggtagtct tgttgatttt gttcatacat ttgtattaat tctgttaggc
      301 attctttcga caaagcccac cattgagaac catgatacaa atcaaattta tggtgtctaa
      361 tttttggggg aagtttaatc atcctcagac aacgattaat tatagctcta aaaattttaa
      421 atgcagttgt gttattccta ttaattctag gataatcatg tttttgata
//
LOCUS       DACDAF010000239          451 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.251, whole genome shotgun sequence.
ACCESSION   DACDAF010000239 DACDAF010000000
VERSION     DACDAF010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.251"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(36..272)
                     /locus_tag="IVZ69_002863"
                     /pseudo
     CDS             complement(36..272)
                     /locus_tag="IVZ69_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          148 a           75 c           77 g          151 t
ORIGIN      
        1 atagaaggac tgaccttctg tctcagattt ttttgttatt tcacttgaat caattgattg
       61 atcaaaaaaa tcctgatttt catgttctca aatgatttaa atccataaga taatcgtttc
      121 agtgtcttga tatggggaat cttggcctct attttgccat tagaataagg gtaaatcata
      181 gcattgtaaa taccttcttc atacgttaaa aggttttgaa gtttcgtgcg aagttgtgca
      241 tcaagtgttt caggaagatt ttttaataac gccgtttgta taattaagcg agacaaataa
      301 aaaagccatt tatgttacac tccaattgta atacccgcta aagcatacaa ggagagtgaa
      361 cataaatgac ttatacccat cttacaccaa acgagcttgt aatgatagaa gcatattttc
      421 atcaagaaac tccggttgct atcgttgcga a
//
LOCUS       DACDAF010000240          438 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.252, whole genome shotgun sequence.
ACCESSION   DACDAF010000240 DACDAF010000000
VERSION     DACDAF010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..438
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.252"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..>438
                     /locus_tag="IVZ69_002864"
     CDS             <1..>438
                     /locus_tag="IVZ69_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8184852.1"
                     /translation="TFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIYNYHG
                     WEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEEGGAS
                     SLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYLK"
BASE COUNT          175 a           57 c           84 g          122 t
ORIGIN      
        1 tacatttgtt tttaagaaaa aagtagtttc agactattta aataacgaag gcggctacaa
       61 atatcttgca cataaatatc aaataaatcg tacactggtt agacattggg taaggattta
      121 taactatcat ggttgggaag gcttggttgg aggtggcaaa agctacacta caaaatttaa
      181 acttgatgtt atagaatata tggaaacaaa tggtctttct atccaagaaa ctgctaaaaa
      241 atttaatatc ggttcaaata gaactctaag taaatggata gagcaatatg aagaaggcgg
      301 tgcttcttca cttgagagcc aaaaaagggg cagaaaaatt agtatgaatt ccaagctaaa
      361 cattcctaaa aaacttaaag atgagtctct tgaagaagaa gttattcgtt taagagcaga
      421 gaacgcatat ttaaaaaa
//
LOCUS       DACDAF010000241          437 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.253, whole genome shotgun sequence.
ACCESSION   DACDAF010000241 DACDAF010000000
VERSION     DACDAF010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 437)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 437)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..437
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.253"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..422)
                     /locus_tag="IVZ69_002865"
     CDS             complement(<1..422)
                     /locus_tag="IVZ69_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphatase"
                     /protein_id="HAP8184853.1"
                     /translation="MRSSKYTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVL
                     KGIEIGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFA
                     QLSEALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQF"
BASE COUNT          147 a           82 c           71 g          137 t
ORIGIN      
        1 aaaaactgcg cttcatattg tttaaattca gcaacggata gaccaaatac ccgaaaacca
       61 tagtcaaaat gagcaaagac atctgcttct ataacaacta gtgcttctga aagttgtgca
      121 aaatactgag gaatcacaat agcaggatcc atatctttga cttcgtcatc taaataatca
      181 aattgaccat tatgatgcac actgagtaat tttaaatcgt aatctttatc ggctaaatag
      241 tcgatgatcc gatccttttc agaagcgatg taaccgattt ctatgccttt taaaacacga
      301 ttgccaaaac gcttatttaa gctatcgatt gtttgactgt acatttcata atcggggata
      361 tcatcgactt tagtaacagg attggctaag tcaaaatgtt cagtatattt tgatgaacgc
      421 atatgtagtc ctcattt
//
LOCUS       DACDAF010000242          412 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.255, whole genome shotgun sequence.
ACCESSION   DACDAF010000242 DACDAF010000000
VERSION     DACDAF010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..412
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.255"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            136..>412
                     /locus_tag="IVZ69_002866"
     CDS             136..>412
                     /locus_tag="IVZ69_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HAP8184854.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTC"
BASE COUNT          140 a           67 c           83 g          122 t
ORIGIN      
        1 gctctataat ttatgggact gatgaatcag aattgattct tcagccccat ttttatttta
       61 ggtattaaaa aacatatcgt tctctagtat gattaaatca cgacaaaata aacaactgag
      121 aggacgatat gctatatgaa tgattctatc aaaaaaatgc tgcgattaat agagaaagat
      181 ttgatgatta cagaggtctc ttacgagacc tttcagaaga aaaagacgtt gatcgtcgat
      241 gctgttttct cacctgctcc ccatacctgt agaaattgtg gttctactgt ggtagatgga
      301 aacgggaaag taattgtagt gaaaaatggg aagaaggaaa cgattgtccg ctttgaacaa
      361 tacaatcaca tgcctttggt tatgcgctta aaaaagcagc gctatacctg ta
//
LOCUS       DACDAF010000243          402 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.256, whole genome shotgun sequence.
ACCESSION   DACDAF010000243 DACDAF010000000
VERSION     DACDAF010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.256"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            123..341
                     /locus_tag="IVZ69_002867"
                     /pseudo
     CDS             123..341
                     /locus_tag="IVZ69_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
BASE COUNT          136 a           58 c           71 g          137 t
ORIGIN      
        1 atcgatcagt tttgaggaaa tgaaattcta gatatttttt gctacataga gttactttca
       61 atatttttta acgtaattag gcagaagtca ctcatcctct ataggtttgt gatgaaattg
      121 ccattgatcc atttaagtaa gagcaaaaaa ctggaggttt atcaggtaat tggtctaatg
      181 gatttaagta tgcggtcacc gtgtatagag ttgcttatga gattcaagaa aataaagtta
      241 ttccagtatt gctatatgga acacataaca atttttatga attagccgag aacactcgca
      301 actttattcg tgtagatgaa tcggcttcgg ttgagttata actttagcta tatcaatcaa
      361 ccgaccgaca tatgttaaat ctatatataa taaaaatacc ta
//
LOCUS       DACDAF010000244          402 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.257, whole genome shotgun sequence.
ACCESSION   DACDAF010000244 DACDAF010000000
VERSION     DACDAF010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.257"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>402)
                     /locus_tag="IVZ69_002868"
     rRNA            complement(<1..>402)
                     /locus_tag="IVZ69_002868"
                     /product="16S ribosomal RNA"
BASE COUNT           79 a          126 c           93 g          104 t
ORIGIN      
        1 atgaccctcc ccggttgagc cgggggcttt cacatcagac ttaagaaacc gcctgcgctc
       61 gctttacgcc caataaatcc ggacaacgct tgccacctac gtattaccgc ggctgctggc
      121 acgtagttag ccgtggcttt ctggttagat accgtcaagg gatgaacagt tactctcatc
      181 cttgttcttc tctaacaaca gagttttacg atccgaaaac cttcttcact cacgcggcgt
      241 tgctcggtca gactttcgtc cattgccgaa gattccctac tgctgcctcc cgtaggagtt
      301 tgggccgtgt ctcagtccca atgtggccga tcaccctctc aggtcggcta tgcatcgtgg
      361 ccttggtgag ccgttacctc accaactagc taatgcaccg cg
//
LOCUS       DACDAF010000245          396 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.258, whole genome shotgun sequence.
ACCESSION   DACDAF010000245 DACDAF010000000
VERSION     DACDAF010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..396
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.258"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
BASE COUNT          129 a           54 c           58 g          155 t
ORIGIN      
        1 gcaaagatat tttcaaaaca ttttttcttg atgtgatatc cttgtctttt ttgtaatgtt
       61 tttaacttat tgcttttgca aaatttattt acctgttttc tggatcaacg atagtgtata
      121 ttatgctatc cttgtttgga ttttaggacg tttaaagagg cactttttta cataacttaa
      181 tccatagacc ttttaagcat gctgtgagat aataataaag aagagtttaa agcgcacccc
      241 aaaccacttc cccataagtg tattacgctt taaactcttt tatatttgaa ttcactaaga
      301 agcataccat atttttgaaa aaaagtgaga aaaaaggctt ataattagga tttagagtaa
      361 ttaattagat gtttatttta taggactgat actata
//
LOCUS       DACDAF010000246          384 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.259, whole genome shotgun sequence.
ACCESSION   DACDAF010000246 DACDAF010000000
VERSION     DACDAF010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..384
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.259"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..>384
                     /locus_tag="IVZ69_002869"
     CDS             <1..>384
                     /locus_tag="IVZ69_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HAP8184855.1"
                     /translation="FDITQTQLKPEDYPKIFPNRVFDFQLDKKGQSELQAGIQAVANN
                     IGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNTRNTPTQHLATSIHELAHA
                     RMHKFSELDTATKELQAEMTSYIVC"
BASE COUNT          141 a           69 c           76 g           98 t
ORIGIN      
        1 tgtttgatat cacacaaaca cagttaaaac ctgaagacta tccgaaaatc tttccgaacc
       61 gtgtctttga ttttcaattg gataaaaaag gacagtcaga acttcaagct gggattcaag
      121 cggtagccaa caatattgga atacaaattc gagatatgac agaaagtgaa gtctatcaaa
      181 gagaattagg acaagcacgt ggggcgtatg ttcgtaacga atttactggc gaagaagaaa
      241 tcgtcatgaa tactcgaaat actcctacgc agcatttagc tacaagtatt catgaattag
      301 cccatgcaag aatgcacaaa ttttcagaat tagataccgc aactaaagaa ttgcaggcag
      361 aaatgacttc ttatattgtg tgca
//
LOCUS       DACDAF010000247          377 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.260, whole genome shotgun sequence.
ACCESSION   DACDAF010000247 DACDAF010000000
VERSION     DACDAF010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.260"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(144..299)
                     /locus_tag="IVZ69_002870"
                     /pseudo
     CDS             complement(144..299)
                     /locus_tag="IVZ69_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
BASE COUNT          127 a           71 c           41 g          138 t
ORIGIN      
        1 tcattgcttg atttcattat tgttaaacaa gaatacaagc aagaaagaac tatagttaat
       61 atgataaaaa ttattaaagt tctatttttc tttcttgtaa tatatgctat agcatttttt
      121 atcactttcc taactactcc tctctatttt cttactccat aactaattgc atccactgga
      181 caagcatttt tacatcgtcc acatctgata cactccagat gattgcaatt ctcaactgaa
      241 tctttattca tttggcaaac ttttttacat tttccacaat taatacactt atccttatcc
      301 tgaatcggct acactagact agacagaaaa aataaggtgt gtagaataat aaaaaacaca
      361 ctggaggatt tttcatg
//
LOCUS       DACDAF010000248          367 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.262, whole genome shotgun sequence.
ACCESSION   DACDAF010000248 DACDAF010000000
VERSION     DACDAF010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.262"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            124..>367
                     /locus_tag="IVZ69_002871"
     CDS             124..>367
                     /locus_tag="IVZ69_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8184856.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIK"
BASE COUNT          150 a           60 c           60 g           97 t
ORIGIN      
        1 cgcactatgc cattacattt atatctacgc gaattgtaaa attaagttag aaaaataaaa
       61 aggcatttat ggtacactca aattgtattt ccgacgaaag aaaacaaagg agtgtaacca
      121 taaatgacct acaaacatct taccatagac gaactgacaa tgatagaatc atattatctt
      181 caacataata agccggttga aatcgctaac cgaatgggac gtgctataca aactatttat
      241 aatgtagtca ataagttcaa gcaaggcaag actgctcttg attattggca ccagtataaa
      301 gaaaataaga aaaaatgtgg tagaaaagtc attcaattac ctgctcatga agtagattac
      361 attaaag
//
LOCUS       DACDAF010000249          343 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.263, whole genome shotgun sequence.
ACCESSION   DACDAF010000249 DACDAF010000000
VERSION     DACDAF010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 343)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 343)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..343
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.263"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            1..270
                     /locus_tag="IVZ69_002872"
                     /pseudo
     CDS             1..270
                     /locus_tag="IVZ69_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876065.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
BASE COUNT          125 a           46 c           64 g          108 t
ORIGIN      
        1 aaatctatat tttgatatac aaattacagc ttcagatact aagttgcata aaccttttcc
       61 ggaccccata caaaaggcaa ttgatgaatt gggcataaaa aataagaaac gatttatatt
      121 ggtgattcat tatatgacat gcaaagtgcg aaagcttgtg ggatagcatt tggtttagct
      181 aaatggggag ccaaaaatat agaaaatttt caaagtgtag atataattat tgattctcct
      241 caagaaatac ttgatttgtt agaaaaatag acaaagagcg tgagataagg atagggtctc
      301 acgctctttg tttttcgcca tttaaagatt gaaatttttg cca
//
LOCUS       DACDAF010000250          338 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.264, whole genome shotgun sequence.
ACCESSION   DACDAF010000250 DACDAF010000000
VERSION     DACDAF010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.264"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..>338
                     /locus_tag="IVZ69_002873"
     CDS             <1..>338
                     /locus_tag="IVZ69_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HAP8184857.1"
                     /translation="MVSGTQNGLDKTHELGDNMAEYSQLWSQMGYSADETFGMLQNGL
                     DAGAYNLDKVNDLVKEMGISLTDGRFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSM
                     IQDFSNMDGQ"
BASE COUNT          123 a           41 c           82 g           92 t
ORIGIN      
        1 atggtttcgg gtactcaaaa cggtttagat aaaacgcacg aattaggcga caatatggca
       61 gaatatagcc aattatggag tcaaatggga tattcagctg atgaaacgtt cggaatgctt
      121 caaaatggtt tagatgcggg tgcttataac cttgataaag tcaatgactt agttaaggaa
      181 atgggaatat cgttaacaga tggtcgattt gagcaaaaca tggatatgtt tagtgaaagt
      241 actagaaaag cttttgaaga gtggaaaaat ggcggaggaa cacaaaaaga cgttattaat
      301 tccatgattc aagattttag caatatggat ggtcaata
//
LOCUS       DACDAF010000251          335 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.265, whole genome shotgun sequence.
ACCESSION   DACDAF010000251 DACDAF010000000
VERSION     DACDAF010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.265"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            62..256
                     /locus_tag="IVZ69_002874"
     CDS             62..256
                     /locus_tag="IVZ69_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184858.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          148 a           47 c           60 g           80 t
ORIGIN      
        1 atcattttca cttacatata tttgaatatt aactaaaaac agcaagaaag aagaggatca
       61 aatgtattat gtagaagtaa aaacaaaagg cgtcaaaaac aaacaatatg tgaaaggtat
      121 cagtaacgaa tatcctttac ttggttcatg gaaagaagct gctccttttt ccaaaccatg
      181 tgccataaaa ataaagaacg agctagaaaa agaactgact tgtggcaaag ctgttgtaga
      241 tatcatcgaa aagtaaatcc aatgtataga aaggaagatc acacatgaaa agcgacgtac
      301 aaattgctaa gattatagaa ttagaagaag aagac
//
LOCUS       DACDAF010000252          335 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.266, whole genome shotgun sequence.
ACCESSION   DACDAF010000252 DACDAF010000000
VERSION     DACDAF010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..335
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.266"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..>335
                     /locus_tag="IVZ69_002875"
     CDS             <1..>335
                     /locus_tag="IVZ69_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HAP8184859.1"
                     /translation="YVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGER"
BASE COUNT          125 a           53 c           77 g           80 t
ORIGIN      
        1 ttatgttcgc cgatttagag aaacgacggt gtttgaggat atttttgcct atattttaga
       61 acaagcagtt aaagcaggtt ttgtaacaga ggataatttg tatctggatt ctacccacat
      121 caaagctaac gccaataaac ataagtttac gaaagaaatg acccatgatg aagcgaaagc
      181 ctatcaggat gaattagaag atgagatcaa tcgtcaacga atagaggctg gaaaacgccc
      241 ttttactttg gacttagaaa aggaagtgaa gctgaaagaa agaaaaataa gtaaagctga
      301 tccggaaagc ggctactacg tcaaaggcga acgag
//
LOCUS       DACDAF010000253          324 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.267, whole genome shotgun sequence.
ACCESSION   DACDAF010000253 DACDAF010000000
VERSION     DACDAF010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.267"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            44..>324
                     /locus_tag="IVZ69_002876"
     CDS             44..>324
                     /locus_tag="IVZ69_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184860.1"
                     /translation="MDSFQRLSLVNQFELLAKFEDQNRSYYERKIEILREGYEYHYDD
                     EIWSDLSEPFPKEDSRFVLDVLNMYRDINFSKSKLNLDENQITNSYYTH"
BASE COUNT          123 a           37 c           55 g          109 t
ORIGIN      
        1 cttataattt tttgttaatg aacaagatag gaagaaacat ttaatggaca gttttcagag
       61 attgtcacta gtaaatcaat ttgagttatt ggctaaattt gaggaccaaa acagatctta
      121 ttatgaaaga aaaatcgaaa tattgagaga aggttacgag tatcattatg atgatgaaat
      181 ttggagtgat ctttctgagc catttccgaa agaagattct cgatttgtat tagatgtatt
      241 gaacatgtat cgagatatca attttagtaa atcaaagcta aacttagatg aaaaccaaat
      301 tactaattca tactatactc attt
//
LOCUS       DACDAF010000254          321 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.268, whole genome shotgun sequence.
ACCESSION   DACDAF010000254 DACDAF010000000
VERSION     DACDAF010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.268"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..>321
                     /locus_tag="IVZ69_002877"
     CDS             <1..>321
                     /locus_tag="IVZ69_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HAP8184861.1"
                     /translation="TQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGLYTK
                     TEHRTVKYLNNLIEQDHRPIKRRNKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFG
                     FSVST"
BASE COUNT          107 a           69 c           63 g           82 t
ORIGIN      
        1 acgcaagcag cctatgcttt cttaaaacga ctccataaac agtttggtga gccgaaagca
       61 attgtgaccg ataaagcacc ttctcttggc tccgccttta gaaagttaca gagtgtgggt
      121 ttatatacta agacagagca ccgaactgtg aagtatctta acaatttaat agaacaagac
      181 catcgaccta ttaaacgacg aaataaattt tatcaaagtc tccgtacagc ctcttccacg
      241 attaagggca tggagaccat tcgaggaata tataaaaaga accgaagaaa tggaacgctc
      301 ttcggctttt cggtgtctac t
//
LOCUS       DACDAF010000255          321 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.denovo.269, whole genome shotgun sequence.
ACCESSION   DACDAF010000255 DACDAF010000000
VERSION     DACDAF010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.denovo.269"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            complement(<1..>321)
                     /locus_tag="IVZ69_002878"
     CDS             complement(<1..>321)
                     /locus_tag="IVZ69_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HAP8184862.1"
                     /translation="ITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKH
                     GMRWTKYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQAR
                     VTSL"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DACDAF010000256        14215 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.070, whole genome shotgun sequence.
ACCESSION   DACDAF010000256 DACDAF010000000
VERSION     DACDAF010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.070"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            105..956
                     /locus_tag="IVZ69_002879"
     CDS             105..956
                     /locus_tag="IVZ69_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP8184863.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(1207..3165)
                     /locus_tag="IVZ69_002880"
     CDS             complement(1207..3165)
                     /locus_tag="IVZ69_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8184864.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(3162..4034)
                     /locus_tag="IVZ69_002881"
     CDS             complement(3162..4034)
                     /locus_tag="IVZ69_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HAP8184865.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(4376..5248)
                     /locus_tag="IVZ69_002882"
     CDS             complement(4376..5248)
                     /locus_tag="IVZ69_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HAP8184866.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            5376..5945
                     /locus_tag="IVZ69_002883"
     CDS             5376..5945
                     /locus_tag="IVZ69_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HAP8184867.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            6012..6749
                     /locus_tag="IVZ69_002884"
     CDS             6012..6749
                     /locus_tag="IVZ69_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HAP8184868.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            6980..8248
                     /locus_tag="IVZ69_002885"
     CDS             6980..8248
                     /locus_tag="IVZ69_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosaminidase"
                     /protein_id="HAP8184869.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            8735..9199
                     /locus_tag="IVZ69_002886"
     CDS             8735..9199
                     /locus_tag="IVZ69_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HAP8184870.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            9183..9812
                     /locus_tag="IVZ69_002887"
     CDS             9183..9812
                     /locus_tag="IVZ69_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HAP8184871.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            10166..11644
                     /gene="msr"
                     /locus_tag="IVZ69_002888"
     CDS             10166..11644
                     /gene="msr"
                     /locus_tag="IVZ69_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Msr family ABC-F type ribosomal protection
                     protein"
                     /protein_id="HAP8184872.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            11691..12137
                     /locus_tag="IVZ69_002889"
     CDS             11691..12137
                     /locus_tag="IVZ69_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HAP8184873.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(12336..12851)
                     /locus_tag="IVZ69_002890"
     CDS             complement(12336..12851)
                     /locus_tag="IVZ69_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HAP8184874.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            12968..14169
                     /locus_tag="IVZ69_002891"
                     /pseudo
     CDS             12968..14169
                     /locus_tag="IVZ69_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
BASE COUNT         4464 a         2569 c         2929 g         4253 t
ORIGIN      
        1 tttttttgct tgacttatct taccacactc tttatgataa aggtgtaatt tataaatgta
       61 cagctgtaaa tcttaacaaa taaaaagaat agggagtggc aaatatgcat tatttagtaa
      121 caggagcaac tggaggtttt ggtggttatg cgctggaatt cttaaaaaag atggttccac
      181 aaaatgaaat ctatgtacta gtacgtagtg aagaaaaagg agaagcactg aaagaagctg
      241 gatttaatat acgtattggt gattatgatg atttagactc aatgaaagaa gcgttgaaag
      301 gaatagatcg attgcttttt gtctctggcg ttccaggaaa tcgtcaagcc gaacataaga
      361 atgtagtgaa ggcagcacaa gcagctgggg tatcttatat cgcttataca agttttgcag
      421 atgccgatca ctcgatcagt gtattagcgc cagatcacca attcactgaa aaaatgatta
      481 aggattcagg tatttcccat acatttttac ggaataattg gtatgtagag aatgaattac
      541 ctatcattgg gcaggcttta aaaactggtc aattcgttta tgctgcagga aatggaaaaa
      601 caggttgggc attgaaacgt gaatatgcag aagctgcagc aaaagtacta gtagaaagtg
      661 actctccaga aatcttagaa ttatccggca atctaactga ctatgaagaa ttagccaagg
      721 cattagagcg tgcgacaggt aaagagttag aaattattga agcaagtgat gcagcgtttg
      781 tcgaaaatct aaaagaagcc ggattccctc aagaagcagc tgacatgttt ttagcgatcc
      841 aacatgatat taaaaaggat cagttagcta tttcctctga tgatttagaa aaagtattgg
      901 gaaaaccatt aacttctctt gaagcagcat taaaagaaat attggatcag gaataatgta
      961 taaagaggtt gtgaaaaagc cgattagttt tgagtatgaa gaaaaatttt gtgaaaaagc
     1021 tgttctgcat caagtaataa gaagagtcaa ataaaaaata gctcttcata tgtttcgttt
     1081 agctggactt attaccgcgg agttggcagg agaacgccgt ttttattcgg aaaaaggagc
     1141 tgagacaaga tttttgtctc agctcctgtt tgtttatcga taaaaaagtc tggggaagac
     1201 gatggctcag gctttgttgg aaacagagcc gattttatca tttgctttta catcacgtgc
     1261 gggttcgatt tctaagcttt ggactttgtc gccatttgtg aatacaacga ccatatccgt
     1321 gtttttgcct gcagattgaa tagcggcaag atcaactaaa gcaatcaatt gacctcttgc
     1381 gactttttga ccttcttcta catataaagt gaatggttcg ccttttaagt caacagtgtt
     1441 gatgcccata tgaagcaaga cttcgatacc agcatctgtt tggattccga cagcatgttt
     1501 cgttgggaaa atgtttgtga tcgtaccagc gattggagag aagatttctc cattttctgg
     1561 taatacagca tagccgtcac ccatcatttt ttccgcgaat acatcatctg aaacttcagt
     1621 gattggaatc agtttcccat ttgcgatagc gtaaatatct tgttcgatcg tttcaccggc
     1681 aaatgtttct gttttaacca cggtgtttgt ttgtgcaggt cgtgctgcag caccaccatg
     1741 tagttttgcc atctcatctg caacgaattg tacttctgta cctacgatga cttgcgcatt
     1801 ttttccgtcg atgatcttca taccaggtac gccagtggct ttgattttat tttgatcgat
     1861 caggcctgta tctttgactt gcaaacgaag gcgtgtagta cagttatcga tcgaagttac
     1921 attgtcggct ccgcctaatg cagcgtagat tttgcttgct tgtgccgcat atttattgtc
     1981 tgaattagtc gttgcagtat cgtcatctga aagatctgct tcctcgcggc caggagtcat
     2041 cagatggaat tttttgatag caaagttaaa gccaaagtag taaatcactg ctgttactaa
     2101 tccttggacg atcaacatca atggctgatt cgcaatcgga tttttcaaag ataggaagta
     2161 atcgacaaat ccggcactaa aggcaaatcc tgctgtccaa tggaagaatg cactcactgc
     2221 taaagaaatc ccagtgaaaa ttgcatgcaa gacatataat ggccaagcaa cgaacataaa
     2281 tgaaaattca agtggttctg tcacaccagt aaagaatgaa gcaaaagctg ctgctagcat
     2341 caaggaagct gtttttgctt tgttttctgg acgtgcattt ctgtaaatag catatgctcc
     2401 tgctggaagc ccgaacatca tgattgggaa aaatccagct tgatacattc ctgttacgcc
     2461 ttttgttcct tcagaagcca aaaatttacc aatatcattg attcctgcta cgtcaaacca
     2521 gaacacggag ttcattgctt gatgcaatcc tgtagggatc agtaaacggt tgaagaagcc
     2581 ataaagacct gcaccacccc agcctaaact caaaatgaat ttagcaaaag aaactaaagc
     2641 agagtaaacc ggaggccata cgagcagtag cactgcactg atcagcaaca tgacaaaggc
     2701 agccaagatt ggcactagac gcttgccgct aaagaaagat aaagccatcg gtaattttgc
     2761 ttcgtggaaa cgattataaa gagctgccgc aatcaatccg gcaataatac caataaatac
     2821 gttactgatc tgagcaaaag atggatcaac tgattctggt ttgatattca ataaagtagc
     2881 tactgaatca gtttttaaaa catttactgg aacttcaaat gcgaccaaac ctgccaaggc
     2941 agcagcacct gatttgtcca ctgacatccc tagtgctaac ccaacggcaa acagcaaagg
     3001 taattgacct aaaactgcgt taccgccagc ttgtaaaaaa tgagcgacaa tgtcgttact
     3061 ataagatgcc caccagtttc cgatccctac tagtaaagca gcagcaggta agaccgcaac
     3121 tggaagttga agggaacgtc ccattcgttg tagatatgct ttcaattttt ttcctcctca
     3181 tgattgttaa catttgtttg tacgattgcg cttcttaaac gctcgatatg gatggccaag
     3241 taacccagtt cttctttcgt gatcgcgagc tggtattctt tggtcagcaa cacacggatt
     3301 tttttagaaa tcttatagct ttctgggtat tttcgtttga ccatttctac gatttccgtg
     3361 tctaaaacag catattgttg cgcatgggtt cgttgtagaa gcagtcgtaa atgattcacc
     3421 agtcttgaat aattcagtga aaatggttct gaatggatat ctgtttccaa ttctgattcc
     3481 actaaatgga tgatgtcaga tacaatcgtc acttcacgga tactgcgatg gttattgttc
     3541 cgaccgcttc gtccgctgtg aatatggatt gcgatatatc ctgcttcgtc ataagtatat
     3601 ggaatcccaa gctcttttgt cagatactct actgcccatt gagcaatact gaattcatca
     3661 ctgtaaagca cttcgatttc tcttaaaagt ttgttgcgga tgacgatacc gttattaatg
     3721 ttctccgcag aaaaagcaat gtggtcggtc aaagcgatca atacatgttc attcaacttt
     3781 tccatcaaaa cagtttccgc atgatcaatg atcgtttctg ctgcaaataa aaagcgttca
     3841 tcaatctgat taagtaaatt ttgcaacttg atttgacctt ctggttccat gacaaatatc
     3901 cgttcgacat cacgatcaaa aatcaaatca tttctttttc tgtcaaatcc aatccctttt
     3961 ccaatagcta ctttttcctg tccaccgtca tctaccaata ctgcattttg attaaagatc
     4021 tttttgattt tcatgcgcgc accctttttg aagatttggt tttcacgttt gctagaccag
     4081 ttgattgcgg ccaaacaaaa atagacacga aaaacctcct agggaaacca tgttcctcag
     4141 agatttttca tgcctagtat gatctagtca catgaaacga attattgtta acgtaatcaa
     4201 ttttatatag acagttatgt tttgtcaatt ctttttttat aattatagta atttactgga
     4261 attatcagaa ataaaaggaa gaaataaatt aagaaactta tgttatttaa tcgttggatc
     4321 ttttgcttat cttattcgtt gttaaaaagc tgaaagcgaa ggaaaaaaac tctacttaac
     4381 tgtatttctc cgttaggaca tctaaaaatt tacgagcagc aggagaaaga ggctggtctt
     4441 ttttccaaat gagattcagt gaagcttgta atggcggatc gagtgggatg aatatttttt
     4501 ccgtcccata agtattgatg atcccatcta gagctaatgc accaaaagtc ccgttatcga
     4561 ccatcaaaga agcattgtac aataagttat atgttccgac gatcgataac tgatctatgc
     4621 tgaaacctag ccattcagct agttgactgt ccactgacgt ttgccgggaa atgatcaaag
     4681 gaacagtttt cagttcctgc ggatggatga cggtttgctt tgctaaagga tgatttcgat
     4741 gtatcaaaag tccccaacga tcttgggctg gcagtcgaaa tgactggtat ttttgtttgt
     4801 ttgtcggttc gattacgagt ccaaaatcaa gtaatccgct atccagtttg tctatgatat
     4861 catctgcatt cccgctatat aaatgaaact ggatatcagg atgcgccttg atcaacgaat
     4921 gaaggctatc agaaatgaaa gagattgctt tagtttcgcc tccgccaatg tagatttctc
     4981 cagagatgat tgcgtcattt gttaaattgt tcgccgtttt ttctaccaac gacaagattt
     5041 cttttccttt tgaataaaga tatcgaccag aatccgtcaa ctgtatctct cgggagcccc
     5101 gagtgaaaag tgtcacacca agttcttctt ctaaatcttt cagttgtttt gagagagtag
     5161 gttgcgtgat atgcagagat tttgctgctc ggctgatatt tttttctcta gctactgcta
     5221 aaaaatacgt cagtatacga atatccattt tttccctcct gtttttaaaa aagcatacca
     5281 ctaagtatag ttaaaaggaa tagttaagta tgttttataa gtattagaca tgataagccg
     5341 tccgttataa agtaaggata aaaggaggga gcaaaatgac aagcctcatc gaaaaacaaa
     5401 tcgtcaataa agagattcga gtaacggatc cgctctttga agtgatccat cagatccaag
     5461 ctgaaaacga agagccttta gcagcgctga atactgggta ccatgaacca gcagatatcc
     5521 gcaaacggct agaaaatatc attagtgaca aagtagatga tacggtgact gttctgctgc
     5581 ctttttatac agatttcggc aaacatatta gtatagggaa aaatgtcttt atcaatcgtc
     5641 aagtgatgtt cgttgactta ggtggcatct gtttagaaga ttcagtattg attggtcctc
     5701 gtgtcaacct catcacggtg aaccatctaa ccgatccaaa agaacgaaga ggcttgtcag
     5761 taaagccaat ccacatcaag aaaaatgctt ggatcggagc aggagcaact attctgccag
     5821 gcgtaacgat tggcgagaat gccattgttg cagcgaatgc aactgttacg aaagatgtcc
     5881 cagacaatac catcgttgca ggaatccctg ccaaaatcgt caaacctgtc gaacggatta
     5941 tttgaacagt aagatgaaat aagagatagt gagtataagc aagagatttt tcaaaacagg
     6001 aggagaatag aatgaatgat ttatcagaaa aagtgattgt catcatgggc gcttcaagcg
     6061 gaatcggtga agcaacaacg aagctattag cagaaaaagg ggctaaacta gttatagctg
     6121 cacgccgaga agatcgccta aaagcaataa aagaatcttt accagaagct gagctatata
     6181 ttcaaacagc agatgtaaga gattttgcac aagtccaagc agttatcgat ttagcgatgg
     6241 aaaagttcgg tcgaatcgat gtattgtaca ataatgcagg aatcatgcca accgctccat
     6301 tagttgaagg tcaccgtgat gaatggcaaa atatgcttga tatcaacatc atgggtgtgt
     6361 taaatggaat ttccgccgta cttccaatca tggaaaaaca aaaatctggg catatcattt
     6421 caactgattc tgtggcggga catgttgttt atcctgattc cgccgtttat tgcggaacaa
     6481 aatttgctgt ccgtgcaatc atggaaggat tacgtcaaga gcaacggcaa aataacatca
     6541 aatctacgat catctctcca ggagctgttc aaactgaatt atatcaaacc atcagcgaca
     6601 aaaaggctgc tcttgaactt catgaagcgc aaaaagaatg gggattgacc tccgaagata
     6661 tagcttctgc tgtagcattt gcgatagaaa cgccagaccg gatgtctgtc agtaacatga
     6721 ttatccgtcc gacgacacag gaagtataat ccataacgga taatatccaa agagaattac
     6781 ttgttaaata gttattcaaa cgaccatcaa tttaaggcgt gaatggagaa gaatattctt
     6841 catttacgtc tttttatgta gaaaaagcaa atttatcaaa aagaaacaaa tgttatttaa
     6901 atatggacat tgacttgctt ttactttttt agttacactg ttatttagga aaagtttcat
     6961 aattcaaagg agaaaaaaga tgaaagcaaa gaatttatta tttagcgtta ttcttttagg
     7021 aaatctagca gttgccaaca caacagtgct agctgaagaa tcgacagaaa ctgtcgcaac
     7081 tcagacatcg agttcttcag aaacaggaat tgaaaacgat acagagagta ctttgcagtc
     7141 agctactgtc tcagaaaata caatttcaac cgaagaacca acaactgaaa caacagaaca
     7201 aacacaaacc gaagacagta catcagcaga agctcagaac aatccagaga atgcagaaga
     7261 aatcacgaac caattgacag atgggcaaac attgacacat acccatcaag cagatttgtc
     7321 tgaattcgaa aactatactg gctatgcttt ttatgctcgc tcatctgcta attctcaaca
     7381 agcgttcatt gatagtattg cctcaactgc acaaagtttg gcaagtgcca atgacttata
     7441 tgcatcagtc atgattgctc aagccatcgt tgaaagtggc tgggggaaca gtactttggc
     7501 ttctgcccct aattacaatc tatttgggat taaaggaagc tataatggcc aatctgttac
     7561 gatgcctact tcggaatatg tgaatgggca atggattacg gtgaatgccg cttttagaaa
     7621 atatccttcg tacaaagaat cattgcaaga taacgtaacg gtattgaaga cgacttcttt
     7681 tcagccaggc gtttactact attccggtgc atggaaaagc aatacgaact cttacaaaga
     7741 tgctacggct tggctaacag gtcgttatgc cactgcgcct aattatggtt ctacattgaa
     7801 caatgtaatc gaaacctata atctgacaca gtatgataca gcaccaactt caacttctcc
     7861 gatgtatcgt ctgtataacc gtcatacagg agaacattta tatacattga atgccggaga
     7921 aaaaaattat ctgccaactg taggctggga atatgaaggg attgcttggc aagcaccaaa
     7981 cagcggacaa cctgtctacc gtttatacaa tccttacagt ggagaccatc attacacaat
     8041 ggcacaatct gagatcaact ctttaacaaa aatcggttgg cgttatgaag gtctaagttt
     8101 ttattctggt ggttccaagc caatttatcg actatttaat ccaaatgaaa aaactggtac
     8161 ccatcactat accttgagtg ctaaggaaag agattggcta acaccgatgg gctggagata
     8221 tgaaggaata ggattttatg gttattaaaa agaggtagtg aaaaagctgc cctgcatcaa
     8281 gtagtaagaa cagccaaaca aaaacagatt ttcatgtttt ttgtttggtt gaacttatta
     8341 ccgcagatgc aagtttttga acaccgttta ctcaaaaaag gttgtgacaa catcttgtca
     8401 taactttttt attactgttt aagcatactg atccaatttc taatattcga cgggattctt
     8461 gcaaaaggcg atttcggaaa tttttggcgg tgtaaaattt tctactgcag aagagctatc
     8521 ttctatagtt tgataagaat caataatctt ggttttagcg ttgtgctttc tttatcattt
     8581 tttccgttca ttctacaaaa aatttctttt ctctatactt ttctattgag agcgtttttt
     8641 ttattacaca gctgattctt tgactttttt ctttttttat tctattattg acaagtcaat
     8701 cgttgacgag tcaattatta gaaaggagga aattatgtct ttagaagaga ttagtcacct
     8761 tttatatcaa atcaaattag ccgatcaaaa aatcgtccag atctttgaag aaaatatcgg
     8821 tataagtctt actagatacg agatcatgat gagactgaaa gaagaaaatc cattgctaca
     8881 aagcagtttg caagaaaagt tgcagattga tcaaggagca gttactcgtc atctgaaggt
     8941 attggaagca aatggctatg tttcgcgtca gagaaatcct cagaacaacc gggaagtgta
     9001 tgtagcgcta acagaaaaag cccagaagaa aatcgagcat tgtgaaatgg accataaaga
     9061 tacaggttcc gtgctatccc cggctttcag cgatgtagaa atgaaacaat ttctaacact
     9121 tttagataaa ttgaataccc aactttgcaa tataacaaca gaaacgaaag aggttaataa
     9181 taatggaaca aaaaaatgat ttttcaacaa ttatgactgg tagaagatcc gttcgcgtat
     9241 atgatgaaac atacaaaatc ccacacgaag aaatgctgga aatgatcaaa gaagcgacga
     9301 ctgcaccttc ttctgtcaat atgcaaccat ggcgctttgt ggtcgctgaa agcgaggaag
     9361 caaaagaaat cttgcgtcct ttgatccgtt tcaatacgag acaaaatgat acttcttctg
     9421 caatggtcat gatttttggc gatatgcaat gttacgaata tggcgaagaa atctataacc
     9481 aagcttacga atcagggaag atgccaaaag aagtcagaga tcaacaatta gctgcgatca
     9541 ttccttatta caagagtttt tcaagagaag aaatgaacga tgtagtcaaa gtcgattcta
     9601 gcttagcggc tatgcaattc atgttagttg cgcgtgatca tggctatgaa acaaatccaa
     9661 ttggtggatt cgaagcagat cagttggcag aggcatttgg tttggataaa gaccgttatg
     9721 ttccagttat tattttatca ataggaaaag cggtagaaga aggttacgag tctgttcgtt
     9781 tagcaccaga aaagatcact acgttcgaat aaaaggtttt cagttactat tcagtagcta
     9841 ttgctttttt tgaatcgtgt gtggtaacct aataaaaaag gaggtcggaa aaatgactgc
     9901 atcgatgaaa ttacgtttcg aacttttgaa taacaactaa ataaattcaa aagacatgta
     9961 taaacaacaa tttcatggat ggagtatgtc cattttttcg aacgacagta gaataggtga
    10021 aagctatgac agatttggtg atttagtcat agttatttcg ttcagagtag gaaaagatgt
    10081 gatgcagttt ttttgcaaac agatttttct gctctttttt agtatcgata attgttgttt
    10141 tacatgaaat aggagtgtaa aacatatgga aaatttagca gtaaatataa caaatctaca
    10201 agtcagcttt ggcaaccagc tagaactatc tattgattct cttcgtgtct atcagcaaga
    10261 tcgtataggg atcataggag aaaatggtgt cggtaaatcg actttgctca aactaatagc
    10321 cggtgaactt tttcccgatc atgggaaaat ccaaacagag atcaccttca actacctgcc
    10381 tcaattaacc tatctcgctg aagcaaagga cctaaatttg gaattagcca gtcatttcca
    10441 gttaagactg gaagaaactt cagagcggaa atggagcgga ggggaagaac gaaagatcga
    10501 gttgatacgt cttctttctt cttatgaaca agggatgctt ctagacgagc caacaaccca
    10561 tctagataga aaaagtattg atcgactgat tgaagagctt cgttattatt atggtacgct
    10621 ggtttttgtt agtcatgatc gctattttct agatgagcta gcatcgaaaa tctgggaagt
    10681 aaaagacgga gaaatccgag agttttcggg gaattatagt gcctatctca ctcaaaagga
    10741 attggagaaa aagactcagc tacgagaagc agagtcgatc atgaaagaga aaaaacgatt
    10801 ggaaaaatcg atccaagaaa agaaaaaaca agcggaaaag ttggaaaaag tgtccagtaa
    10861 aaagaaaaag caacaaatca gaccggatcg gttgtcttcc tctaaacaaa aagacagtgt
    10921 acaaaaagcc atccaaaaga atgcgaaaac attagagaga agactccaaa aaataggaga
    10981 aacaaccaag ccgcagcaga tgaaacaaat ccgttttcca gtaccaaaat ctcttgaact
    11041 ccacagccgc tatcccatca tgggacaaaa tgtccaattg gaaagaagtg ggagaacatt
    11101 actggtaaat ggtgattttc agttttcttt aggtaaaaaa atcgcgattg tcggtgaaaa
    11161 tggttcaggt aagacaacct tattagaaca tatccgcaaa caaggagaag gaatccttct
    11221 ctctccgaaa gtaagctttc aagtatatca gcaaaagggt tatcaaatga catctgaaga
    11281 atccatcatt cgttttgtca tgagacaaac agagttttca gaatcgcttg tccgtagttt
    11341 gctgaatcac ttagggtttg ctcaggaaac tttgacgaaa ccgttatgta cattaagtgg
    11401 gggagaagcg acccgtctga cgattgcttt gctttttact aagccaagta atgtgttgct
    11461 gttagatgaa ccgactaatt ttattgatat ggcaacgatc gaagctttag agaagctaat
    11521 gcaaatatat ccgggaacga ttttgtttac ttctcatgat tcttactttg tcgagcgtac
    11581 ggctgatgaa gtttatgaaa taaaagggca gaaaataaaa aaagtactta cgagaaattt
    11641 ttaaatgtgc tacgatgatt ttcgtgacaa atttaaagga gtggtacaga ttgcctacaa
    11701 ataaaaaaga aggaataatt tttacaacaa tgatgtgttt tttgatggtc ttggggatga
    11761 gcgcgtataa tttatggctg catcaagatc ttcatttatc aagtttgttg attggtctag
    11821 tgcctggatt cgtggtggct ttcattttgg atgtcttcat catcggtgtg ctggcgaaaa
    11881 aaattgcctt taaactacca gtaaatccag aaagcaaggt ccaaatgatc ttaactattt
    11941 catgcttgat ggttttagga atggtgacat gtatgtcttt attcggtgtg atcatggaac
    12001 aaggaatacc tgatcaatta ttctctgctt atatgaatgc ttggaaaatg aatgtgattg
    12061 ccgctttacc gttgcagttg atcatcgttg gcccgctttc aagaagtgtg ctaaaagcaa
    12121 ttcaaagtaa tgaatgatgg aacactgtta tttgaaaaaa ggccttggca tgctttttgt
    12181 catagtctct tgaatgcagt tctagaaaaa tagtgatccg aacgataggt tttggcctgt
    12241 cgttcggatc gctttttctt ttccaactgt attgctcttt tattgaagat aatttgctct
    12301 tcaatagata tttctagaaa ggttctgttt atcccttact caaaaaactg ctgcatttgt
    12361 tctcttactt gctgacacca ttggagttcc tgctgacaaa gcataattct gcgctggatc
    12421 acaacataac gtccaaattc ttgtttcttg tctagcgaga ggtcattcaa ttttttttga
    12481 tttttttgca tgattttgtt cagctgttgt tctctagtga atagcagtcc agtagctgtt
    12541 gttttatcga gcgtcgaaaa agcatagatt tttgctagaa attcatcttt ttgcgtagga
    12601 gcgggagttt cctctttgat ccattcctct acaagagcac gtccttcatc agtcaagtgg
    12661 tagatctttt tttgagagtg ctcgtctttg tccaaaacgg tcacataacc ctgctggtct
    12721 aacttggcaa gcgttgtata gatctgactg tgatgggctt cccaaaaaat tgtgatcagc
    12781 tgcttcaatt catacccaga acgtggtttg gataaaagca cgcataataa tatataggct
    12841 aaagtattca taaaaatcct acctctcgtc ttattttctt tattatatca cagtaaagtt
    12901 tccacgtttt acatgtgcat atttacatgt aaaataaatc atgtatgatg ctaatagaga
    12961 gaaagggatg gaaatattgg agaatcaaat agatatacaa gaacaaacaa atgaagaaac
    13021 aaaggggaaa agttcagcgc tagttgtagc agctacctgt atgatcgctt ttatgggagt
    13081 gggtctagta gacccaatct taaaaacgat tgctgcacag ttaaacgcta cgccagctga
    13141 aacgaccctg ttatttacta gttacatgtt agtcactggt gtggtgatgc tatttacagg
    13201 tttcttatct agtcggatcg gtttgaaaaa acattgatga caggattgtt tatcatcgtt
    13261 gtattcgctg gtcttggcgg attatctggg aatatcggaa tgctgattgg gttacgtgcc
    13321 ggctggggtg tcgggaatgc tttatttgtc tctactgctt tagcaacgat cgtcagtatt
    13381 ttagttggta acacagaaaa agcaatcatg atgtatgaag cagcacttgg ctgcggaatg
    13441 gctgttggcc ctctagtcgg tggggtcttg ggcagtggtt catggcgtta tccatttttt
    13501 ggggtagcat ttttgatgtt ttgcggtttt atagccctag cggtactttt acctgaaact
    13561 gagaaaccaa agagaaaagt aggcctttgg gaaggtgtca aagcgttaag caatcataaa
    13621 cttcgttcag ttggactaat cgcattgtta tataatttcg gattctttac tttacttgcg
    13681 tatgcgccat ttttattgat tggctattct gaattagaag tcggttttgt attttttggc
    13741 tggggtgtgc ttctggctat tgcttcgatt ttcgttgcac cggctcttga gcggaagttt
    13801 acgacttatc ggacaatttt agcagcattt gtcttattca ttatttgttt gctgttatta
    13861 ggagctggaa cttctatgcc agtccttgta ccgatcagca ttgtgttagc aggatttttc
    13921 caaggaatta tcaatacact gttgacgacg attgctatgg aaataccagg tctgcaacga
    13981 aacgttgctt cgtccagcta tagttttgtc cgctttttcg gtggagcttt agcaccattt
    14041 attgcaggtg tgattggtga acatattggt gaaagctatg cgttttattt tgcaggtgcc
    14101 attgttctta tcagtgtatg ttgtatcatt tatcaccgta attattttgc tacaaatgaa
    14161 gaagaataag aaatcagagg ttgtgaaaaa gctgtcctgc atcaagtcat aagaa
//
LOCUS       DACDAF010000257        11908 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.080, whole genome shotgun sequence.
ACCESSION   DACDAF010000257 DACDAF010000000
VERSION     DACDAF010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11908)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11908)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11908
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.080"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            <1..1344
                     /locus_tag="IVZ69_002892"
     CDS             <1..1344
                     /locus_tag="IVZ69_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HAP8184875.1"
                     /translation="NQEGIIADVQTKEKKTNSPSLFSLSSLQSKVNQLYKATASQTLK
                     AMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMVQTEPRKRYVDG
                     SKVQEHHAIIPTKQVPTESALAKMDDLQRKIYALVVKTTVAMFLPDYLYEETKIQTKV
                     ADLLFQSIGKTPKQEGWKILFKQQTKEEKEDVQTLPLVIIGERAEVGVKSVEKETQPP
                     KAFTEGTLLTAMKTANKTVDDEEAIKILQEVEGIGTEATRASIIEALKQKEYIQVIKN
                     KLVVTEKGKLLCQAVESQHLLTSAEMTAKWETYLKKIGKREGNQENFITNIKKFIVHL
                     LEAVPNDIEKLNFSDYQEQKEKEAEKSIVGKCPKCGNNIVLKKSFYGCSNYPECKFTL
                     AEHFRKKKLTKTNVKELLEGKETLVKGIKNKEKKPYNAVVKIGEKGYIDFISFSK"
     gene            1464..1703
                     /locus_tag="IVZ69_002893"
     CDS             1464..1703
                     /locus_tag="IVZ69_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013646120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-binding protein"
                     /protein_id="HAP8184876.1"
                     /translation="MIVGNLGAQKEKRNDTPISAKKDIMGDKTVRVRADLHHIIKIET
                     AKNGGNVKEVMEIRLRSKLKSVLIVHYLKILYNRN"
     gene            1752..1836
                     /locus_tag="IVZ69_002894"
                     /pseudo
     CDS             1752..1836
                     /locus_tag="IVZ69_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuator leader
                     peptide ErmL"
     gene            1961..2698
                     /gene="erm(B)"
                     /locus_tag="IVZ69_002895"
     CDS             1961..2698
                     /gene="erm(B)"
                     /locus_tag="IVZ69_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004292767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HAP8184877.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGNIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            complement(2895..5861)
                     /locus_tag="IVZ69_002896"
     CDS             complement(2895..5861)
                     /locus_tag="IVZ69_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HAP8184878.1"
                     /translation="MKIARGRELLTPEQRQAFMQIPEDEWILGTYFTFSKRDLEIVNK
                     RRREENRLGFAVQLAVLRYPGWPYTHIKSIPDSVIQYISKQIGVSPSSLDHYPQRENT
                     LWDHLKEIRSEYDFVTFTLSEYRMTFKYLHQLALENGDAIHLLHECIDFLRKNKIILP
                     AITTLERMVWEARAMAEKKLFNTVSKSLTNEQKEKLEGIITSQHPSESNKTILGWLKE
                     PPGHPSPETFLKIIERLEYIRGMDLETVQISHLHRNRLLQLSRLGSRYEPYAFRDFQE
                     NKRYSILTIYLLQLTQELTDKAFEIHDRQILSLLSKGRKAQEEIQKQNGKKLNEKVIH
                     FTNIGQALIKAREEKLDVFKVLESVIEWNTFVSSVEEAQELARPADYDYLDLLQKRFY
                     SLRKYTPTLLRVLEFHSTKANEPLLQAVEIIRGMNESGKRKVPDDSPVDFISKRWKRH
                     LYEDDGTTINRHYYEMAVLTELREHVRAGDVSIVGSRQYRDFEEYLFSEDTWNQSKGN
                     TRLSVSLSFEDYITERTSSFNERLKWLAANSNKLDGVSLEKGKLSLARLEKDVPEEAK
                     KFSASLYQMLPRIKLTDLLMDVAHITGFHEQFTHASNNRKPDKEETIIIMAALLGMGM
                     NIGLSKMAEATPGLTYKQLANVSQWRMYEDAMNKAQAILVNFHHKLQLPFYWGDGTTS
                     SSDGMRMQLGVSSLHADANPHYGTGKGATIYRFTSDQFSSYYTKIIHTNSRDAIHVLD
                     GLLHHETDLNIEEHYTDTAGYTDQIFGLTHLLGFKFAPRIRDLSDSKLFTIDKASEYP
                     KLEAILRGQINTKVIKENYEDVLRLAHSIREGTVSASLIMGKLGSYSRQNSLATALRE
                     MGRIEKTIFILNYISDESLRRKIQRGLNKGEAMNGLARAIFFGKQGELRERTIQHQLQ
                     RASALNIIINAISIWNTLHLTTAVEYKKRTGSFNEDLLHHMSPLGWEHINLLGEYHFN
                     SEKVVSLNSLRPLKLS"
     gene            6007..6582
                     /locus_tag="IVZ69_002897"
     CDS             6007..6582
                     /locus_tag="IVZ69_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016204422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HAP8184879.1"
                     /translation="MRKIGYIRVSSTNQNPSRQFQQLNEIGMDIIYEEKVSGATKDRE
                     QLQKVLDDLQEDDIIYVTDLTRITRSTQDLFELIDNIRDKKASLKSLKDTWLDLSEDN
                     PYSQFLITVMAGVNQLERDLIRMRQREGIELAKKEGKFKGRLKKYHKNHAGMNYAVKL
                     YKEGNMTVNQICEITNVSRASLYRKLSEVNN"
     gene            6796..7491
                     /gene="vanR"
                     /locus_tag="IVZ69_002898"
     CDS             6796..7491
                     /gene="vanR"
                     /locus_tag="IVZ69_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance DNA-binding
                     response regulator VanR"
                     /protein_id="HAP8184880.1"
                     /translation="MSDKILIVDDEHEIADLVELYLKNENYTVFKYYTAKEALECIDK
                     SEIDLAILDIMLPGTSGLTICQKIRDKHTYPIIMLTGKDTEVDKITGLTIGADDYITK
                     PFRPLELIARVKAQLRRYKKFSGVKEQNENVIVHSGLVINVNTHECYLNEKQLSLTPT
                     EFSILRILCENKGNVVSSELLFHEIWGDEYFSKSNNTITVHIRHLREKMNDTIDNPKY
                     IKTVWGVGYKIEK"
     gene            7469..8623
                     /locus_tag="IVZ69_002899"
     CDS             7469..8623
                     /locus_tag="IVZ69_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanA-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HAP8184881.1"
                     /translation="MVIKLKNKKNDYSKLERKLYMYIVAIVVVAIVFVLYIRSMIRGK
                     LGDWILSILENKYDLNHLDAMKLYQYSIRNNIDIFIYVAIVISILILCRVMLSKFAKY
                     FDEINTGIDVLIQNEDKQIELSAEMDVMEQKLNTLKRTLEKREQDAKLAEQRKNDVVM
                     YLAHDIKTPLTSIIGYLSLLDEAPDMPVDQKAKYVHITLDKAYRLEQLIDEFFEITRY
                     NLQTITLTKTHIDLYYMLVQMTDEFYPQLSAHGKQAVIHAPEDLTVSGDPDKLARVFN
                     NILKNAAAYSEDNSIIDITAGLSGDVVSIEFKNTGSIPKDKLAAIFEKFYRLDNARSS
                     DTGGAGLGLAIAKEIIVQHGGQIYAESNDNYTTFRVELPAMPDLVDKRRS"
     gene            8838..9806
                     /locus_tag="IVZ69_002900"
     CDS             8838..9806
                     /locus_tag="IVZ69_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-A"
                     /protein_id="HAP8184882.1"
                     /translation="MNNIGITVYGCEQDEADAFHALSPRFGVMATIINANVSESNAKS
                     APFNQCISVGHKSEISASILLALKRAGVKYISTRSIGCNHIDTTAAKRMGITVDNVAY
                     SPDSVADYTMMLILMAVRNVKSIVRSVEKHDFRLDSDRGKVLSDMTVGVVGTGQIGKA
                     VIERLRGFGCKVLAYSRSRSIEVNYVPFDELLQNSDIVTLHVPLNTDTHYIISHEQIQ
                     RMKQGAFLINTGRGPLVDTYELVKALENGKLGGAALDVLEGEEEFFYSDCTQKPIDNQ
                     FLLKLQRMPNVIITPHTAYYTEQALRDTVEKTIKNCLDFERRQEHE"
     gene            9799..10830
                     /gene="vanA"
                     /locus_tag="IVZ69_002901"
     CDS             9799..10830
                     /gene="vanA"
                     /locus_tag="IVZ69_002901"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanA"
                     /protein_id="HAP8184883.1"
                     /translation="MNRIKVAILFGGCSEEHDVSVKSAIEIAANINKEKYEPLYIGIT
                     KSGVWKMCEKPCAEWENDNCYSAVLSPDKKMHGLLVKKNHEYEINHVDVAFSALHGKS
                     GEDGSIQGLFELSGIPFVGCDIQSSAICMDKSLTYIVAKNAGIATPAFWVINKDDRPV
                     AATFTYPVFVKPARSGSSFGVKKVNSADELDYAIESARQYDSKILIEQAVSGCEVGCA
                     VLGNSAALVVGEVDQIRLQYGIFRIHQEVEPEKGSENAFITVPADLSAEERGRIQETA
                     KKIYKALGCRGLARVDMFLQDNGRIVLNEVNTLPGFTSYSRYPRMMAAAGIALPELID
                     RLIVLALKG"
     gene            10836..11444
                     /locus_tag="IVZ69_002902"
     CDS             10836..11444
                     /locus_tag="IVZ69_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-A"
                     /protein_id="HAP8184884.1"
                     /translation="MEIGFTFLDEIVHGVRWDAKYATWDNFTGKPVDGYEVNRIVGTY
                     ELAESLLKAKELAATQGYGLLLWDGYRPKRAVNCFMQWAAQPENNLTKESYYPNIDRT
                     EMISKGYVASKSSHSRGSAIDLTLYRLDTGELVPMGSRFDFMDERSHHAANGISCNEA
                     QNRRRLRSIMENSGFEAYSLEWWHYVLRDEPYPNSYFDFPVK"
BASE COUNT         3892 a         2135 c         2412 g         3469 t
ORIGIN      
        1 aatcaagagg ggataattgc tgatgttcaa accaaagaga agaaaacgaa tagtccgagt
       61 ttgttttctt taagtagttt gcaatcaaaa gtcaatcagc tttataaagc gacagcgagc
      121 caaactttaa aagctatgca aggactgtat gaagcaaaat tattgagtta tccaagaaca
      181 gatacaccat ttattacaga gaacgaattt gcttatttaa aagcgaattt tggcaaatat
      241 agcggttttt taggacttga tcttgaaatg gttcaaacag agcctagaaa gcgttatgtg
      301 gacggtagta aggtacagga acaccacgcc attatcccaa caaaacaagt acctaccgaa
      361 tctgcattag cgaaaatgga cgatttacaa cgaaaaattt atgctttagt cgttaaaacg
      421 accgttgcca tgtttttacc tgattacttg tatgaagaaa ccaagataca aacgaaagta
      481 gctgatttgc tgtttcaatc gatcggaaag acaccaaagc aagaagggtg gaaaattctt
      541 ttcaaacaac aaaccaaaga agaaaaagag gacgttcaaa cgttaccact cgttatcatt
      601 ggcgaacgtg ccgaagttgg tgttaagagt gttgaaaaag aaacgcaacc gccaaaagct
      661 tttacagagg gtacattatt aactgctatg aaaacggcga ataaaacggt tgatgatgaa
      721 gaagcaatca agattttaca agaagttgag gggattggaa cagaagcgac aagagcaagt
      781 attattgaag cgttaaaaca aaaagaatat atccaagtga ttaagaataa gcttgttgta
      841 actgaaaaag gaaaattatt gtgccaggca gttgaaagtc agcacctttt aacgagtgct
      901 gaaatgacgg ctaaatggga aacgtattta aaaaaaatcg gtaaaagaga aggcaatcaa
      961 gagaacttta ttacgaatat caaaaaattc attgttcatt tactggaagc tgtacctaac
     1021 gatatagaaa aactaaattt ttctgattac caggaacaga aagaaaaaga agcagaaaaa
     1081 agtattgtag gaaaatgtcc taagtgtggc aacaatattg tattaaaaaa atcgttttat
     1141 ggttgttcaa attatcctga atgtaagttt actttagctg aacattttag aaagaaaaaa
     1201 ctaaccaaaa cgaatgtaaa agaattactg gagggaaaag aaaccctggt aaaaggaatc
     1261 aaaaacaaag agaaaaagcc ctacaatgcc gttgtaaaaa ttggggaaaa gggatatatt
     1321 gattttatat ctttctcaaa ataaacataa aagcccttta aagagggctt ttatatatta
     1381 atcacaaatc acttatcaca aatcacaagt gatttgtgat tgttgatgat aaaataagaa
     1441 taagaagaaa tagaaagaag tgagtgattg tgggaaattt aggcgcacaa aaagaaaaac
     1501 gaaatgatac accaatcagt gcaaaaaaag atataatggg agataagacg gttcgtgttc
     1561 gtgctgactt gcaccatatc ataaaaatcg aaacagcaaa gaatggcgga aacgtaaaag
     1621 aagttatgga aataagactt agaagcaaac ttaagagtgt gttgatagtg cattatctta
     1681 aaattttgta taataggaat tgaagttaaa ttagatgcta aaaatttgta attaagaagg
     1741 agggattcgt catgttggta ttccaaatgc gtaatgtaga taaaacatct actgttttga
     1801 aacagactaa aaaacagtga ttacacagat aaataaatac gttagattaa ttcctaccag
     1861 tgactaatct tatgactttt taaacagata actaaaatta caaacaaatc gtttaacttc
     1921 tgtatttatt tatagatgta atcacttcag gagtgattac atgaacaaaa atataaaata
     1981 ttctcaaaac tttttaacga gtgaaaaagt actcaaccaa ataataaaac aattgaattt
     2041 aaaagaaacc gataccgttt acgaaattgg aacaggtaaa gggcatttaa cgacgaaact
     2101 ggctaaaata agtaaacagg taacgtctat tgaattagac agtcatctat tcaacttatc
     2161 gtcagaaaaa ttaaaactga acattcgtgt cactttaatt caccaagata ttctacagtt
     2221 tcaattccct aacaaacaga ggtataaaat tgttgggaat attccttacc atttaagcac
     2281 acaaattatt aaaaaagtgg tttttgaaag ccatgcgtct gacatctatc tgattgttga
     2341 agaaggattc tacaagcgta ccttggatat tcaccgaaca ctagggttgc tcttgcacac
     2401 tcaagtctcg attcagcaat tgcttaagct gccagcggaa tgctttcatc ctaaaccaaa
     2461 agtaaacagt gtcttaataa aacttacccg ccataccaca gatgttccag ataaatattg
     2521 gaagctatat acgtactttg tttcaaaatg ggtcaatcga gaatatcgtc aactgtttac
     2581 taaaaatcag tttcatcaag caatgaaaca cgccaaagta aacaatttaa gtaccgttac
     2641 ttatgagcaa gtattgtcta tttttaatag ttatctatta tttaacggga ggaaataatt
     2701 ctatgagtcg cttttgtaaa ttataaaaga attgttttaa tgcaggtata aaagatgaac
     2761 ccgcaccaac accgccacca attttagata gctttgattg gtacattttt agcgctattc
     2821 ggggtagcgt caggaaaatg cggatttaca acgctaagcc tattttcctg acgaatccct
     2881 cgtttttaac aacgttaaga aagttttagt ggtcttaaag aatttaatga gactactttc
     2941 tctgagttaa aatggtattc tcctagtaaa ttaatatgtt cccaacctaa gggcgacata
     3001 tggtgtaaca aatcttcatt aaagctacct gtccgttttt tatattcaac tgctgttgtt
     3061 aggtggagag tattccaaat acttatagca ttgataatta tgtttaaagc actggctctt
     3121 tgcaattgat gctgtatggt gcgttctcta agctcacctt gttttccgaa gaaaatagct
     3181 cttgccaatc cattcatggc ttctccttta ttcaatcctc tttgtatttt tcttcttaat
     3241 gattcatccg atatataatt caaaataaag atcgtttttt ctattcggcc catctcacgt
     3301 aaggctgtag ctaagctgtt ttgtcttgaa taggaaccta gcttccccat aataagggat
     3361 gctgaaactg ttccctccct tatagaatga gctaatcgca aaacatcctc ataattttct
     3421 ttaatgacct ttgtatttat ttgtccacgt aaaatggctt ctagttttgg atactcactt
     3481 gctttatcta tcgtaaataa ttttgagtcc gataaatccc ttattcttgg ggcaaattta
     3541 aatcctaata aatgagtcag tccgaatatt tggtcagtgt aaccggcagt gtctgtataa
     3601 tgttcctcta tgtttagatc cgtctcatga tgtaacaaac catccaaaac atgaatcgca
     3661 tctcttgaat tagtatgaat aatctttgtg tagtaagaag agaattgatc acttgtaaat
     3721 cggtagatgg tggctccttt tccagttcca taatgtggat ttgcatctgc atgtagtgat
     3781 gaaacaccta gctgcattct cataccatct gacgaagatg ttgtaccgtc gccccaatag
     3841 aaaggcaatt gtaatttatg atgaaagttt actaatatgg cttgggcttt attcatggca
     3901 tcttcataca tgcgccattg agatacattg gctagttgct tatatgtaag tccgggtgtg
     3961 gcttcggcca tcttgctcaa gccaatattc attcccattc ctaaaagggc agccatgata
     4021 atgattgttt cttccttatc tggttttcga ttattggaag catgagtgaa ttgctcatga
     4081 aatcctgtta tatgggccac atccatgagt aaatcagtta attttattct tggtagcatc
     4141 tgataaaggc ttgcactaaa tttttttgct tcttctggaa catctttttc taagcgtgca
     4201 agtgatagct ttcctttttc aagagaaacc ccatctaact tattggaatt ggcagctaac
     4261 cactttaacc tttcattaaa gctgctggtt ctctccgtta tataatcttc gaatgataaa
     4321 ctaactgata atctcgtatt ccccttcgat tgattccatg tatcttccga aaacaaatat
     4381 tcctcaaaat ccctatattg tctgctgcca acaatggaaa catctcctgc ccgaacatgc
     4441 tcccgaagtt ctgttaaaac agccatttca tagtaatgac gattaattgt tgtaccatca
     4501 tcctcgtata aatgtctttt ccatcgtttt gaaataaaat ccacaggtga gtcatcaggc
     4561 acttttcgct ttccagattc gttcattcct cggataatct caacagcttg taaaagtggc
     4621 tcatttgcct ttgtagaatg aaattccaat actcttaata gcgttggcgt atattttctt
     4681 agtgaataaa accgtttttg cagtaagtct aaataatcat agtcggcagg acgtgcaagt
     4741 tcctgagcct cttctactga agagacaaag gtattccatt caataaccga ttctaaaacc
     4801 ttaaaaacgt ctaatttttc ctctcttgct ttaattaatg cttgtccgat gttcgtaaag
     4861 tgtataactt tctcatttag ctttttaccg ttttgtttct ggatttcctc ttgagcctta
     4921 cgaccttttg ataacaaact aagtatttgc ctatcatgaa tttcaaacgc tttatccgtt
     4981 agctcctgag taagttgtaa taaatagatg gttaatatcg aataacgttt attttcttga
     5041 aagtcacgga atgcatacgg ctcgtatctt gagcctaagc gagacagctg caacaggcgg
     5101 ttacggtgca aatgactaat ttgcactgtt tctaaatcca ttcctcgtat gtattcgagt
     5161 cgttctatta tttttagaaa agtttcgggt gaaggatgac ccggtggctc ttttaaccaa
     5221 cccaatatcg ttttattgga ttcggatgga tgctgcgagg taataatccc ttcaagcttt
     5281 tctttttgct catttgttag agatttacta accgtattaa atagcttctt ttcagccatt
     5341 gcccttgctt cccacaccat tctttcaagt gtagtgatag caggcagtat aattttgttt
     5401 tttcttagaa aatctatgca ttcatgcagt agatgaatgg catcaccatt ttccaaagct
     5461 aattgatgaa ggtacttaaa tgtcattcga tattcactca gggtaaaagt tacaaagtcg
     5521 tattcacttc gaatttcttt caaatgatcc caaagtgtat tttccctttg aggataatga
     5581 tcaagcgagg atggactaac accaatctgt ttcgatatat attgtatgac cgaatctggg
     5641 atgcttttga tatgagtgta tggccaaccg ggataccgaa gaacagctaa ttgaacagca
     5701 aatcctaaac ggttttcttc cctccttcgc ttattaacta tttctaaatc ccgtttggaa
     5761 aaagtgaagt aggtccccag tatccattca tcttcaggga tttgcataaa agcctgtctc
     5821 tgttccggtg taagcaattc tctacctctc gcaattttca ttcagtatca ttccatttct
     5881 gtattttcaa tttattagtt caattatata tcaatagagt gtactctatt gatacaaatg
     5941 tagtagactg ataaaatcat agttaagagc gtctcataag acttgtctca aaaatgaggt
     6001 gatattttgc ggaaaatcgg ttatattcgt gtcagttcga ctaaccagaa tccttcaaga
     6061 caatttcagc agttgaacga gatcggaatg gatattatat atgaagagaa agtttcagga
     6121 gcaacaaagg atcgcgagca acttcaaaaa gtgttagacg atttacagga agatgacatc
     6181 atttatgtta cagacttaac tcgaatcact cgtagtacac aagatctatt tgaattaatc
     6241 gataacatac gagataaaaa ggcaagttta aaatcactaa aagatacatg gcttgattta
     6301 tcagaagata atccatacag ccaattctta attactgtaa tggctggtgt taaccaatta
     6361 gagcgagatc ttattcggat gagacaacgt gaagggattg aattggctaa gaaagaagga
     6421 aagtttaaag gtcgattaaa gaagtatcat aaaaatcacg caggaatgaa ttatgcggta
     6481 aagctatata aagaaggaaa tatgactgta aatcaaattt gtgaaattac taatgtatct
     6541 agggcttcat tatacaggaa attatcagaa gtgaataatt agccattctg tattccgcta
     6601 atgggcaata tttttaaaga agaaaaggaa actataaaat attaacagcc tcctagcgat
     6661 gccgaaaagc cctttgataa aaaaagaatc atcatcttaa gaaattctta gtcatttatt
     6721 atgtaaatgc ttataaattc ggccctataa tctgataaat tattaagggc aaacttatgt
     6781 gaaagggtga taactatgag cgataaaata cttattgtgg atgatgaaca tgaaattgcc
     6841 gatttggttg aattatactt aaaaaacgag aattatacgg ttttcaaata ctataccgcc
     6901 aaagaagcat tggaatgtat agacaagtct gagattgacc ttgccatatt ggacatcatg
     6961 cttcccggca caagcggcct tactatctgt caaaaaataa gggacaagca cacctatccg
     7021 attatcatgc tgaccgggaa agatacagag gtagataaaa ttacagggtt aacaatcggc
     7081 gcggatgatt atataacgaa gccctttcgc ccactggagt taattgctcg ggtaaaggcc
     7141 cagttgcgcc gatacaaaaa attcagtgga gtaaaggagc agaacgaaaa tgttatcgtc
     7201 cactccggcc ttgtcattaa tgttaacacc catgagtgtt atctgaacga gaagcagtta
     7261 tcccttactc ccaccgagtt ttcaatactg cgaatcctct gtgaaaacaa ggggaatgtg
     7321 gttagctccg agctgctatt tcatgagata tggggcgacg aatatttcag caagagcaac
     7381 aacaccatca ccgtgcatat ccggcatttg cgcgaaaaaa tgaacgacac cattgataat
     7441 ccgaaatata taaaaacggt atggggggtt ggttataaaa ttgaaaaata aaaaaaacga
     7501 ctattccaaa ctagaacgaa aactttacat gtatatcgtt gcaattgttg tggtagcaat
     7561 tgtattcgtg ttgtatattc gttcaatgat ccgagggaaa cttggggatt ggatcttaag
     7621 tattttggaa aacaaatatg acttaaatca cctggacgcg atgaaattat atcaatattc
     7681 catacggaac aatatagata tctttattta tgtggcgatt gtcattagta ttcttattct
     7741 atgtcgcgtc atgctttcaa aattcgcaaa atactttgac gagataaata ccggcattga
     7801 tgtacttatt cagaacgaag ataaacaaat tgagctttct gcggaaatgg atgttatgga
     7861 acaaaagctc aacacattaa aacggactct ggaaaagcga gagcaggatg caaagctggc
     7921 cgaacaaaga aaaaatgacg ttgttatgta cttggcgcac gatattaaaa cgccccttac
     7981 atccattatc ggttatttga gcctgcttga cgaggctcca gacatgccgg tagatcaaaa
     8041 ggcaaagtat gtgcatatca cgttggacaa agcgtatcga ctcgaacagc taatcgacga
     8101 gttttttgag attacacggt ataacctaca aacgataacg ctaacaaaaa cgcacataga
     8161 cctatactat atgctggtgc agatgaccga tgaattttat cctcagcttt ccgcacatgg
     8221 aaaacaggcg gttattcacg cccccgagga tctgaccgtg tccggcgacc ctgataaact
     8281 cgcgagagtc tttaacaaca ttttgaaaaa cgccgctgca tacagtgagg ataacagcat
     8341 cattgacatt accgcgggcc tctccgggga tgtggtgtca atcgaattca agaacactgg
     8401 aagcatccca aaagataagc tagctgccat atttgaaaag ttctataggc tggacaatgc
     8461 tcgttcttcc gatacgggtg gcgcgggact tggattggcg attgcaaaag aaattattgt
     8521 tcagcatgga gggcagattt acgcggaaag caatgataac tatacgacgt ttagggtaga
     8581 gcttccagcg atgccagact tggttgataa aaggaggtcc taagagatgt atataatttt
     8641 ttaggaaaat ctcaaggtta tctttacttt ttcttaggaa attaacaatt taatattaag
     8701 aaacggctcg ttcttacacg gtagacttaa taccgtaaga acgagccgtt ttcgttcttc
     8761 agagaaagat ttgacaagat taccattggc atccccgttt tatttggtgc ctttcacaga
     8821 aagggttggt cttaattatg aataacatcg gcattactgt ttatggatgt gagcaggatg
     8881 aggcagatgc attccatgct ctttcgcctc gctttggcgt tatggcaacg ataattaacg
     8941 ccaacgtgtc ggaatccaac gccaaatccg cgcctttcaa tcaatgtatc agtgtgggac
     9001 ataaatcaga gatttccgcc tctattcttc ttgcgctgaa gagagccggt gtgaaatata
     9061 tttctacccg aagcatcggc tgcaatcata tagatacaac tgctgctaag agaatgggca
     9121 tcactgtcga caatgtggcg tactcgccgg atagcgttgc cgattatact atgatgctaa
     9181 ttcttatggc agtacgcaac gtaaaatcga ttgtgcgctc tgtggaaaaa catgatttca
     9241 ggttggacag cgaccgtggc aaggtactca gcgacatgac agttggtgtg gtgggaacgg
     9301 gccagatagg caaagcggtt attgagcggc tgcgaggatt tggatgtaaa gtgttggctt
     9361 atagtcgcag ccgaagtata gaggtaaact atgtaccgtt tgatgagttg ctgcaaaata
     9421 gcgatatcgt tacgcttcat gtgccgctca atacggatac gcactatatt atcagccacg
     9481 aacaaataca gagaatgaag caaggagcat ttcttatcaa tactgggcgc ggtccacttg
     9541 tagataccta tgagttggtt aaagcattag aaaacgggaa actgggcggt gccgcattgg
     9601 atgtattgga aggagaggaa gagtttttct actctgattg cacccaaaaa ccaattgata
     9661 atcaattttt acttaaactt caaagaatgc ctaacgtgat aatcacaccg catacggcct
     9721 attataccga gcaagcgttg cgtgataccg ttgaaaaaac cattaaaaac tgtttggatt
     9781 ttgaaaggag acaggagcat gaatagaata aaagttgcaa tactgtttgg gggttgctca
     9841 gaggagcatg acgtatcggt aaaatctgca atagagatag ccgctaacat taataaagaa
     9901 aaatacgagc cgttatacat tggaattacg aaatctggtg tatggaaaat gtgcgaaaaa
     9961 ccttgcgcgg aatgggaaaa cgacaattgc tattcagctg tactctcgcc ggataaaaaa
    10021 atgcacggat tacttgttaa aaagaaccat gaatatgaaa tcaaccatgt tgatgtagca
    10081 ttttcagctt tgcatggcaa gtcaggtgaa gatggatcca tacaaggtct gtttgaattg
    10141 tccggtatcc cttttgtagg ctgcgatatt caaagctcag caatttgtat ggacaaatcg
    10201 ttgacataca tcgttgcgaa aaatgctggg atagctactc ccgccttttg ggttattaat
    10261 aaagatgata ggccggtggc agctacgttt acctatcctg tttttgttaa gccggcgcgt
    10321 tcaggctcat ccttcggtgt gaaaaaagtc aatagcgcgg acgaattgga ctacgcaatt
    10381 gaatcggcaa gacaatatga cagcaaaatc ttaattgagc aggctgtttc gggctgtgag
    10441 gtcggttgtg cggtattggg aaacagtgcc gcgttagttg ttggcgaggt ggaccaaatc
    10501 aggctgcagt acggaatctt tcgtattcat caggaagtcg agccggaaaa aggctctgaa
    10561 aacgcattta taaccgttcc cgcagacctt tcagcagagg agcgaggacg gatacaggaa
    10621 acggcaaaaa aaatatataa agcgctcggc tgtagaggtc tagcccgtgt ggatatgttt
    10681 ttacaagata acggccgcat tgtactgaac gaagtcaata ctctgcccgg tttcacgtca
    10741 tacagtcgtt atccccgtat gatggccgct gcaggtattg cacttcccga actgattgac
    10801 cgcttgatcg tattagcgtt aaaggggtga taagcatgga aataggattt acttttttag
    10861 atgaaatagt acacggtgtt cgttgggacg ctaaatatgc cacttgggat aatttcaccg
    10921 gaaaaccggt tgacggttat gaagtaaatc gcattgtagg gacatacgag ttggctgaat
    10981 cgcttttgaa ggcaaaagaa ctggctgcta cccaagggta cggattgctt ctatgggacg
    11041 gttaccgtcc taagcgtgct gtaaactgtt ttatgcaatg ggctgcacag ccggaaaata
    11101 acctgacaaa ggaaagttat tatcccaata ttgaccgaac tgagatgatt tcaaaaggat
    11161 acgtggcttc aaaatcaagc catagccgcg gcagtgccat tgatcttacg ctttatcgat
    11221 tagacacggg tgagcttgta ccaatgggga gccgatttga ttttatggat gaacgctctc
    11281 atcatgcggc aaatggaata tcatgcaatg aagcgcaaaa tcgcagacgt ttgcgctcca
    11341 tcatggaaaa cagtgggttt gaagcatata gcctcgaatg gtggcactat gtattaagag
    11401 acgaaccata ccccaatagc tattttgatt tccccgttaa ataaactttt aaccgttgca
    11461 cggacaaact atataagcta actctttcgg caggaaaccc gacgtatgta actggttctt
    11521 agggaattta tatatagtag atagtattga agatgtaagg cagagcgata ttgcggtcat
    11581 tatctgcgtg cgctgcggca agatagcctg ataataagac tgatcgcata gaggggtggt
    11641 atttcacacc gcccattgtc aacaggcagt tcagcctcgt taaattcagc atgggtatca
    11701 cttatgaaaa ttcatctaca ttggtgataa tagtaaatcc agtagggcga aataattgac
    11761 tgtaatttac ggggcaaaac ggcacaatct caaacgagat tgtgccgttt aaggggaaga
    11821 ttctagaaat atttcatact tccaactata tagttaagga ggagactgaa agagagtata
    11881 aaatattttg tgtaaatgaa aaaatcca
//
LOCUS       DACDAF010000258        11895 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.081, whole genome shotgun sequence.
ACCESSION   DACDAF010000258 DACDAF010000000
VERSION     DACDAF010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.081"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            160..1281
                     /locus_tag="IVZ69_002903"
     CDS             160..1281
                     /locus_tag="IVZ69_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HAP8184885.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            1539..3041
                     /locus_tag="IVZ69_002904"
     CDS             1539..3041
                     /locus_tag="IVZ69_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HAP8184886.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            3108..3635
                     /locus_tag="IVZ69_002905"
     CDS             3108..3635
                     /locus_tag="IVZ69_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HAP8184887.1"
                     /translation="MLYVTRHGETTWNAQGLVCGRADVPLTEKGQMQAQKLAEKVVDL
                     PVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYDGLPSKDENFQKAR
                     LAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIRVINAYFHPMPNEG
                     FFTFMVDNTELVSYE"
     gene            3846..4907
                     /locus_tag="IVZ69_002906"
     CDS             3846..4907
                     /locus_tag="IVZ69_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HAP8184888.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            4910..5806
                     /gene="murQ"
                     /locus_tag="IVZ69_002907"
     CDS             4910..5806
                     /gene="murQ"
                     /locus_tag="IVZ69_002907"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HAP8184889.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            5820..7802
                     /locus_tag="IVZ69_002908"
     CDS             5820..7802
                     /locus_tag="IVZ69_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HAP8184890.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(7867..8313)
                     /gene="nrdI"
                     /locus_tag="IVZ69_002909"
     CDS             complement(7867..8313)
                     /gene="nrdI"
                     /locus_tag="IVZ69_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HAP8184891.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            8524..9948
                     /locus_tag="IVZ69_002910"
     CDS             8524..9948
                     /locus_tag="IVZ69_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HAP8184892.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(10129..10902)
                     /locus_tag="IVZ69_002911"
     CDS             complement(10129..10902)
                     /locus_tag="IVZ69_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HAP8184893.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(10899..11804)
                     /locus_tag="IVZ69_002912"
     CDS             complement(10899..11804)
                     /locus_tag="IVZ69_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HAP8184894.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
BASE COUNT         3794 a         2091 c         2606 g         3404 t
ORIGIN      
        1 ccattgctcc ggccccagct attgcgattt tcatgttttt tctctccttt attcaatgag
       61 ttccctttta gtatatagaa aaatggaaga aaatagcatt gttttgtttg aaaaaaatga
      121 aaaaaagtgt cttacttaag aagaaagtga gggatacaga tggatatttt ggcggcaatt
      181 gattcattta aaggaagtgc ttcttcattt gaactaaatc aggcagttct aaatggctgg
      241 gaagatcgta aaggaagaaa aatcaatgtg ccgattgcag atggcggaga aaatactgca
      301 gaagcaatct attacgcgct caggggaaca tggcgtacca ttgatgggat ggatctctta
      361 ttccgtcagc gaaaaatcag ctatttattg acaacttggc aaggaaaaaa caccgcagtc
      421 atcgaatctg cacaagcatt ggggttagat ctacttgata aaccaacgga tcaaactatc
      481 cgacttgctt ccagttatgc cttaggagaa cttattaaag atgcactgct tcaagaagta
      541 gaacaaatta ttgtcacttt aggaggaagc gggtgtagcg atggtggtct aggattactc
      601 caatccttgg gtgcttcttt agaagggtac acagaaggaa atcctttatt atctactaaa
      661 aaacttcatt ttgatcgaag aaacgttctt gtttctaaag taaaattgat tatcgctgca
      721 gatgttacca atccatatac aggtcaacaa ggagctgctt ggcaatttgg aagacaaaaa
      781 ggaggaatag atacgacgct agctttctta gataaacaag caggaaagat tgctcagcaa
      841 ataaaagatt tctgggaggt ggatttagat gatattccag gaagtggagc agcaggcggt
      901 attggtggag cccttttttt gttgggagcg aagatggttt ctggtttcga tttagtcagc
      961 caaatcactg gattggaaaa aaagatcgaa caagcagatg tcatcattac aggagaaggg
     1021 cggatcgatc agcaaacgat ccacggaaaa gttccatacg gtgtagcagt gcttgcaaaa
     1081 aaatatcgaa aaccaataat cgctatttgc ggaagtagag accaagagct agaaggactt
     1141 tctgattttc tcccaattgt cttaagtatt catttgggtc caataggttt agaagaagca
     1201 atggaacaca ggcaaacatt agaaaaaaca aaaatcttag gacagacact tagcagattt
     1261 ttcaccatcc tcccgaagta gttgacaaaa tcattttctt tatgctatcg taatttcaaa
     1321 tataggacaa agtgagggat ccgtgcattg aaaaattaag tcgattgatg aaagctgcat
     1381 tcagactgta ccttgtggag acaaggaagc agtgtgcaga ttttcgggat tggcttggtt
     1441 ttttcgatgt atgggtcttt ttgtgtgtat ccaacccttg tatcctcttt agccagttct
     1501 gaaaatagga ctggtctttt tttacgaggt gatggaaaat gtctaaaatc gaaataaaaa
     1561 atctgacatt cggctacgac agccaaggca cattattatt tgaacaagca aatctaaatt
     1621 ttgacacaca atggaaacta ggacttatcg gacgaaacgg tcgaggaaag acaactttac
     1681 tgaatattct acaaaacaaa ctaccttatc aagggcaagt aatccatcag caagaatttg
     1741 cctatttccc gcaacagaca aaagataaag aacgtttaac ctattacgtg ttaaatgata
     1801 ttacggattt tgagatatgg gaaatcgaaa gagagctcca attgatgcaa acagatcctg
     1861 aaatcttatg gagagaattc agcacactat cggggggaga gaagacaaaa gtcctactgg
     1921 cacttttatt tgtggatgac actcatttcc cgttaatcga tgaaccaacg aatcatttgg
     1981 atatctctgg tagaaaacaa gtagcggctt atttgaaaaa gaaaaaacaa ggcttcatcg
     2041 tggtcagcca tgaccgggga tttatcgatg aagtagtgga ccatgtttta gcaatcgaaa
     2101 aaagtcaact ggaactttat caagggaatt tctctatcta tgaagaacag aaaaaacttc
     2161 gtgatgaatt tgaaatggct caaaatgaaa aattgaaaaa agaagtcagt aggctaaaga
     2221 aaacagcagc tgaaaaagcc gaatggtctc gttcccgaga aggagataaa acaaagaaac
     2281 aagtcggatt catcgatact gaatctagac gagtgaataa aggagcagtg ggtgctgatg
     2341 ctgcacggac gatgaaacga tccaaagcaa tcgtgaatcg gatggagacc cagatcagcg
     2401 agaaagaaaa actattaaaa gatatcgaat atatcgattc tttgacgatg aatagccaag
     2461 cgtctcacca taagcgactt ttaagcgtag aagatcttca attagggtat gaaaatctgt
     2521 tattcgagcc aattcatttt acaatcgagc ctcatcagcg ggtggcgatt tcaggtccta
     2581 acggtgcagg aaagtcatcc attatccatt atcttctggg ggcattcaac ggcaaggtta
     2641 taggagaaaa ataccagcca aaacatctga gcattagtta tgcaagccaa aattatgaag
     2701 acaatcgagg aacgttggcg gaatttgcag agaaaaacca agtagactac caagcatttt
     2761 tgaacaacct ccgaaagctt gggatggaaa gagatgtttt tcataacaag atcgagcaga
     2821 tgagtatggg ccaacggaaa aaagtggaat tggctaaatc tttatcacag ccagctgaac
     2881 tatatacatg ggatgaacca ttgaattatt tggatgtctt caatcaagaa caattagaac
     2941 aactgatctt gaacgtgaaa cctgccatgt tactagtgga acatgatcaa accttcctgg
     3001 ataaagtatc tactgagatt atttctcttg agagaatcta acccttgtaa tctcaagaac
     3061 aacaaggtat ggttaagggg aactttgcca acgaaggaga gaatcacatg ctttatgtaa
     3121 cgagacacgg agaaacaact tggaacgcac aaggattagt ttgcggacgg gcagatgtgc
     3181 cgctgactga aaaaggacag atgcaggcac agaaactagc agaaaaggta gtagatttgc
     3241 ctgttccaat cacgaaaatc atccattccc ctcttcaacg agcaagagat acagcacaag
     3301 cagttgctga tcgtctcagc ttgccgctga ccgttgatga acgattggta gaaatggatt
     3361 ttggggatta tgatggactg ccaagcaaag atgagaactt tcaaaaagca cgtttagcgt
     3421 tcgctgtacg attcccaaat ggggagtcag tcttagatgt gtatgcacgg atcgttcctt
     3481 tattgaaaga atgcatcgaa gacgaagaaa atgtctatct gttagtttgc cataatgcct
     3541 tgataagagt gatcaatgct tattttcatc cgatgcctaa tgaggggttc tttacattca
     3601 tggtagataa tacagaattg gtttcttatg agtaattatg tttttgtgtt atttaaataa
     3661 aatatttcaa ggcactgctt ttgcttagca gtgccttttt taggttatga caattctttt
     3721 gataatataa actcaacctt tagaaatgaa atttaattgt tttaataaaa gtattgaaat
     3781 tttgtttctt tagatatata ctctagtcat agaaatgaag acggatacag aaaaagaggg
     3841 ataatatgtt tggcttttca atatttatga acgattcttt gtcagaagag aagaaacagt
     3901 atatccgcca aatggcatcc aatggctttg tcggtatttt cacttccatg catataccag
     3961 aagatgatgt ttcggcatat caaaagcgat tgatcgaact aggaagcgaa gcgaaaaaga
     4021 ataaactaga attgatggtc gatatttcag gagaggcatt ggaacgagcg ggtttttcat
     4081 tagaagatct aacgcctttg aaagcaattg gtgtaacagg tttaagaatg gattatcata
     4141 tttccaatca gcagattgcc gactggtcac atcaattgaa aatcagtttg aatgctagca
     4201 cgatcacgcc taaagatatc gatgaattga aagaagcaga agctgatttc tcacagattg
     4261 aagcttggca taattattat ccacgtcccg aaacagggct ggacaaagaa tggtatcaga
     4321 aaaaaaatca atggctcaaa attcaaggtc tccttgtcca aggttttgta ccaggagata
     4381 cagagttgag aggcccacta tatcaaggat tgccaacttt ggaagaacat cgagggatcc
     4441 atcctcttgc aggcgctcta gatctattag caagtaacac ggatattgtt tacatcggag
     4501 atgcaggtct gtcagaaaac gttcaggagc aatttgcttc tttccaaaaa gaacagacag
     4561 tcttgctcca tacggaacct gtagatgaag aattttacga atatatatta gggaagcata
     4621 cgaatcggca agacgatgca agagatgtca tacgaagcgt agatgcacgt tttcgagaga
     4681 ttccgcctat cccagcaaga aatacagcta cgcgtatgaa agggtctatt actttagata
     4741 acgaaaagta tttgcgctat atgggtgaga tccaattaac caaatatgat ttgccagcgg
     4801 atgaaaaagt gaatgtagta gctaaagtta tcaaagaaga gctaccattg atcaaccaaa
     4861 tcaaagctgg tatgaactat caatttataa gaaaagaagg aagataaaaa tgagcaaaat
     4921 caatttagag aacctaacaa cggaacgcag aaaccaagaa acttttggat tagatgagat
     4981 gagtatttct caagccgttc aactaatgaa caaagaagat cagaaagtgg ccgctgcggt
     5041 tgaaaaagaa ctgacaagta tcgaaccagt gattgctaac acgattgagt cctttaaaaa
     5101 aggtggacgt ctgatttata tgggagccgg aacaagtgga agactaggtg tgttagatgc
     5161 tgctgaatgc gtaccgacat tcggtgtaga accggaaatg gtcataggtc taattgctgg
     5221 tggagaagaa gcaatgactg tagctgtcga aggggccgaa gattcttatg agctagggca
     5281 agaagatcta atcaagctga atttgacaaa aaatgatata gttattggta tcgcagctag
     5341 cggtcgtaca ccatatgtga tcggtggatt agattacgca aaatcgatcg gtgctgtcac
     5401 aggaacgatt tcttgcaata aacaagccga aatcagtaaa cacgcggatt tcccaatcga
     5461 agtcgatgca ggtccagaat ttttgacagg ctctactcga ttgaagtcag gaacagcaca
     5521 aaaacttatc ttgaatatga tttctactat cagtatgatt ggtataggta aagtattcaa
     5581 taacttgatg gtcgatgtca aaccaacaaa cgaaaaacta atcgaacgct caaaacgaat
     5641 catcatgcaa gcgacagaag ctgattacga aacagctgaa aagtactttg aagaagcaga
     5701 tcaaaatgtt aagctggcta tcgtcatgat tttgacaaat agtgataaag aggaagctca
     5761 agcaaaatta gctgaagcaa acggatttgt aaaagggacc ttatgagggg gaaaagacca
     5821 tggcaaaaaa cgaactgact ttggaagaac tggcaaaaca aatttataaa ggggcaggcg
     5881 gcatgggcaa tgtagaaagc attgtccact gcatgactcg tgtgcgtatg aagatcatca
     5941 atgatgatct tgtaaatgtc tctgaattaa aagcgattcc aggagtgctt ggtgtagtag
     6001 aagatgaaca gcttcaagtc atcatcggac ctgggaaagt gaacaaagta gcacagcaaa
     6061 tggttgattt ggcaggcgtg aaattaggag aaaaactttc ttctgtaagt acagctacag
     6121 caaattcatc agcatctgga aaagaccgtg taaacgaacg ggcacaagaa atgaaagcgg
     6181 cacaaaaatc gaaacaaaaa ccatctaaaa tcaaatcggt attaaaagac atttctaata
     6241 tctttgtgcc aatgattcct gcatttgtcg gtactgggat cgtggcaggg attgccgcag
     6301 ttttagcaaa cttagtcaca gccggaacac ttgatgcagc aacatggcaa caatatatcg
     6361 atgtgatgaa catcttgaaa aacgggatgt ttagctacct agttatctat acaggtatca
     6421 atgctgcaca agtttttggt gcaacaccaa ctcttggtgg agttatcggg gccgttgtga
     6481 tgctgacagg gatgaatccg gaagcaccac tgaaaaactt atttactggt gaagctcttg
     6541 cagctggaca aggtgggatc ctaggtgtca tcttcgctgt ttggctattg tcaatcgttg
     6601 agaaaaaact gcataaagta gtacctgatg cggtagatat catcgttaca ccaactcttt
     6661 cattgattgc catcggtctg attgaaattt tcttcatcat gcctttagca ggtttcattt
     6721 ctgatggcat ggtcggtggg atcaactggg tacttggcgt tggtggagca tttgccggct
     6781 tcgttctagg cacattattc ttgccgatgg ttatgttcgg actgcatcaa attttgactc
     6841 caatccatgt gcaaatgatt gatgaaactg gtcgtacgct attgcttcca attcttgcga
     6901 tggctggtgc aggacaagtg ggtgcagcat tggcattatg gattcgctgc aaaaaagata
     6961 aagaattaac agaaatgatc aaaggagctt taccagtcgg gatcctagga atcggcgaac
     7021 cattgattta cggagtaaca ttacctctag gacgcccatt tattactgct tgtatcggtg
     7081 gaggtatcgg cggggcagtg atcggaatga tcggaaatgt cggggctatc gctattggac
     7141 cttcaggagc cgctttgatc ccattgatct ctgacggtaa atggttaggc tacatccttg
     7201 gattattggc agcttatgct ggtggcttcg ttgctacatt cttcttcggt attcctaaag
     7261 accgtttaga aaaagaagaa ttagcgactg aaacagccac agtaaatgaa gtgcctgaaa
     7321 aagtagtacc tcaaacttca gctgaaagtg tgactatcct ctcatcagtt gctgacggaa
     7381 cagttgtttc tttagataaa gcaagtgatc cagtttttgc acaaaagatg atgggtgaag
     7441 gctactttgt agaaccagaa aacggacata tctattctcc agttactggg gtagtcagct
     7501 ctgtcttccc aacgaaacac gctattggga tcacaacgcc aaatggttta gaaatcttgc
     7561 ttcatatggg aatcaacaca gttgacttag gcggtacgcc atttgatgtg aaagtaacag
     7621 aagggcagca agtgacacct gatacgcttg tagcagaagc tgacttagaa gcgatcaaag
     7681 cagcaggcaa agaaacatcc atgatcgtct tggtaaccaa tatggatcgt gtaaaaaact
     7741 ttgtcttgga aaaaacaggt aaagcaaaag caaaagcacc tgtgatggat gtcaaagctt
     7801 aatatgatag aaacaataga aacgaaagaa gaaactgaaa tctatttttc agcttcttct
     7861 tttttattat ttattgtttt ctgctaaaat ctgataaatt cgtgtcacat cagatggtgt
     7921 tccccgtaat tcataatctg ccaagaaagg aaagccaaat gtttgtgcat attgtttggc
     7981 tgttagacaa tactgattat tgaagttttt atttccgcta ccgactacac caagacaaag
     8041 tttatgattg tcttcatgtt ccagatattc acgcatcgtt tcggtcaaga tttctgtatc
     8101 accgttatct aaaccatttc cgccgtctaa ataagtagga acgaaagtaa aaaatggttc
     8161 tgtttctttc gtaaaatcac tattttcatg gatttctttt aaagtaactt caggattgac
     8221 aggatcttct gcatgcattt tttcagcata ttctgctaga tgtttggcaa aggcacgcgt
     8281 atttcctgaa atcgatatat ataaaatgtt catggatcat cctccaattc tttcctttta
     8341 gtatagcatc ttttttaagt tttttggtgg tgtaatttgg aaagggacta ggcgctttgc
     8401 ttgtataatg agaaaaaagc cggtagaatt atatttctat taaagttttt attaattaag
     8461 taaaaataaa aaaggtttgt tatacttttt gataaaagcg gttttatttt ggaggatgct
     8521 tacatggata cagagcaaca gaaaaaagga attggtttaa ttccacttgc tgccttagta
     8581 attggttcag cgattggagg tggcgtattt ggtattatga cggacatctc cggatcggct
     8641 ggcggcccag ctattttcag ttgggtactc gtaggaacag caatgttgat gctctccttg
     8701 tcgatcaata atatcaataa aaaacgtcca gatttaaaag gcgggatctt tagttacgca
     8761 gaagaaggtt ttggccgttt cgctggtttt atcagcggtt ggggttactg gctcacatgc
     8821 tggttaggca acgtagcttt tgcaacattg ttgatgagcg cattaggata tttcttccca
     8881 gtatttgaag gtgggcaaaa tctggcatcg atcgtgatga gtacagtctt tttatgggga
     8941 tatgcatggc tagtgaatcg gggagtcgaa aatgctagtt tcgtcaatgc tatcgtcaca
     9001 ttctgtaaat tagtgccatt atttttattt attgtagtag ctatcagcac gttttcgatc
     9061 caacaattca ttgataactt ttctagcgac attatattga atgcgaatgg acagccgatc
     9121 ccgttttcca gtcaagtatt gagttgcatc atggtgatgc tttgggtatt tgttggtatt
     9181 gaaggagcct ctgtcgtagg ttcacgagca aaaaaacaat cagatgttgg gaaagcaacg
     9241 attctaggga tattcggctt gattattatt tacgtcttgg tttccatgct tccatatggg
     9301 acaatgacga tgaatcagct gcaaacgatc aaggcgcagc ctgctatggg ctatgtgttt
     9361 gaaatgatgg ttggtaaatg gggagcagtc gtgatcaacg gcggtttgat catttcttta
     9421 gttggtgttt ggctctcatg gacgatctta ccgattgaaa caatgggaaa catggctgaa
     9481 gacggacttt tgcctaaagc atggggaaaa ctcaacaaaa atggggcacc aacttatgct
     9541 atcgtattga cgacgttatg tacgaatgtc tttttacttt cattattatt cactgacagt
     9601 gcttataact ttgcttacac acttggtaca gcagctattt tcttcacgtg gcttttctta
     9661 ggattgtacc aaatgaaact ttcttatcag cggaaagaat gggtccaatt tttagtaggg
     9721 cttttagcaa gtgcctttca agtatgggct atgctagtcg tagcctttaa tgaagtaatg
     9781 cttgttcttg ttcttttctt gccaggcatt tatttttacc tcaaagcacg taaggagcaa
     9841 aacgagcctg tacaacatat ccacttagat aagattttac ttataggtgt gacgatggtc
     9901 ggagtgattg caatggtttt atttgccact gggatgcttc acgtatagaa gtataaaaga
     9961 agtataaaga gaggttgtga gcctgtcgtt tattcaaaaa catactagga aaggagctgt
    10021 gacacaaatg ttgtcacagc tcctttttca gaataaacgg tgtttaagag acagccaatc
    10081 ggcaataagg ctgaacgtct ctttcacagc ctcttttttg atgagtcatc atacattttt
    10141 tcgcttaaat acgagatatc ctaatgctaa gaacaaaacg atgtaagcta aattaccgaa
    10201 tagcatttga ttagtagaaa gatgagtcaa ttgcttcatg atctcttcgt ttccaatttg
    10261 gttttgcaga ttcaacatac tgatcggatt ccatttgatc cactcccatt tttggatgag
    10321 tgcaataagg ataccagata tgattgacga agcaaaataa aagacgattc ctgctgagat
    10381 ggatgcaccg gaactattga taaagcaagc aatcatcaac actaaactta aaatcagcca
    10441 taaaccgata taactaccca aagtataagt gaacaagctt tggatcagtg tttgaccagt
    10501 agaaaccttc tccgtgaagg aaatcgaagg gaaaagaatc agtttcatca acacagtgac
    10561 aataatagct aaaaggtata aataaacaga ataaataact aatgtgatcc atttgcttac
    10621 taatatttct cctcgagaat actttcgata aaggagattt ttcaatgtac catattgtgc
    10681 ttccatcgaa atgatcgtgc ttgcagctgc aatcatgata aagacaatcc aagatgtggc
    10741 actaaaaagc tgagcagtca tttcaactgg atcaatgatc gtcgtgtatt ttttggctag
    10801 aagtgctgtt cctatgagca aaacaactaa tagaacagat aaaacagcag ttgacttttt
    10861 cttgatcaat ttaaataatt cttgttttac aagcaatgtc atttttcttc ttcccccttt
    10921 actgaatcca gaatttccaa tagagaagat tccaaatcat tcgtcagatg ctggacgtct
    10981 gtcacatgga tattttgtgc agacaatagc tggatcacgg ttcctaataa ttcttcgttt
    11041 tcttttaaaa gcttgatttt atcaggatct tccaaagtat atccagcttc tgtcaagatc
    11101 gttcgagcag ctagatcatt tgttgtagag ataacgatga aatcttgcgc tgtttggttc
    11161 aattcagcca ttgtacattg tttgatgatc tttccttgat tgatcaggat cagctcatcg
    11221 accatttttt caagctcgct gagtaagtga ctggagatca agaaagaggt gccctgagta
    11281 gccaagtcgg taatgatttt tcgcacatct cttgttgctt gtggatccaa accgttcatc
    11341 ggctcatcta aaataacgat agacggatgg ttcagtaagg caagagcaat tcccaatttt
    11401 tgtttcattc ccaacgagta ggatttcgct tttttgtgaa tgtacttttc catcttgagc
    11461 tgattcacga tagtgtcgat agcagataca tcgttggttt cagagaataa cttcagatga
    11521 tcatagcctg ttaagaatgg atagataccc gggtattcga tcaatgctcc tacttgttcc
    11581 aaccctttat gactagaggg agaaatctca ttttcaccaa tacagattgt tccatctgag
    11641 taatggatca gtcctaaaat agctttcatg atcgttgttt ttccagcgcc attaggacct
    11701 actaatccaa cgattttgcc aggggataag ctaaaactga catcgctgag ggcttgtttg
    11761 tgaccaaagt tcttggataa ttcttggacc gaaagacttt tcaaaaatat tcactccttt
    11821 tctatagata gtacaagcat acacctgatg agtggagaag tcgctaggtc attggactta
    11881 tttcttattt tttca
//
LOCUS       DACDAF010000259         8378 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.109, whole genome shotgun sequence.
ACCESSION   DACDAF010000259 DACDAF010000000
VERSION     DACDAF010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8378
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.109"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            9..1049
                     /locus_tag="IVZ69_002913"
     CDS             9..1049
                     /locus_tag="IVZ69_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HAP8184895.1"
                     /translation="MYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLPQRK
                     KIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLGKVQ
                     MEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVSPLP
                     LGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYSPVS
                     TPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIVNTQ
                     LKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRLNSR
                     IDKVRYMFNKIT"
     gene            1147..1335
                     /locus_tag="IVZ69_002914"
     CDS             1147..1335
                     /locus_tag="IVZ69_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HAP8184896.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(1393..1746)
                     /locus_tag="IVZ69_002915"
     CDS             complement(1393..1746)
                     /locus_tag="IVZ69_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HAP8184897.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            2277..2699
                     /locus_tag="IVZ69_002916"
     CDS             2277..2699
                     /locus_tag="IVZ69_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HAP8184898.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            2696..2926
                     /locus_tag="IVZ69_002917"
     CDS             2696..2926
                     /locus_tag="IVZ69_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HAP8184899.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            3424..3624
                     /locus_tag="IVZ69_002918"
     CDS             3424..3624
                     /locus_tag="IVZ69_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HAP8184900.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            3651..4844
                     /locus_tag="IVZ69_002919"
     CDS             3651..4844
                     /locus_tag="IVZ69_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HAP8184901.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(4912..6477)
                     /gene="guaA"
                     /locus_tag="IVZ69_002920"
     CDS             complement(4912..6477)
                     /gene="guaA"
                     /locus_tag="IVZ69_002920"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HAP8184902.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(6536..7459)
                     /locus_tag="IVZ69_002921"
     CDS             complement(6536..7459)
                     /locus_tag="IVZ69_002921"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HAP8184903.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            7655..8260
                     /locus_tag="IVZ69_002922"
     CDS             7655..8260
                     /locus_tag="IVZ69_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HAP8184904.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
BASE COUNT         2725 a         1516 c         1590 g         2547 t
ORIGIN      
        1 ttacagaaat gtatacttca ataaatggtg aattatgtaa gattgataga gcttattctg
       61 gagaaattgt tattttgcaa aatgagtttt tgaagttaaa tagtgttctt ggagatacaa
      121 aactattgcc acagagaaaa aagattgaaa atccgcaccc tctactacaa acaactgttg
      181 aaccgagtaa acctgaacag agagaaatgt tgcttgatgc ccttttggaa atctcagata
      241 gtgatccgct tctacgatat tacgtggatt ctacgacaca tgaaattata ctttctttct
      301 tagggaaagt acaaatggaa gtgattagtg cactgttgca agaaaagtat catgtggaga
      361 tagaactaaa agagcctaca gtcatttata tggagagacc gttaaaaaat gcagaatata
      421 ccattcacat cgaagtgccg ccaaatcctt tctgggcttc cattggttta tctgtatcac
      481 cgcttccgtt gggaagtgga atgcagtatg agagctcggt ttctcttgga tacttaaatc
      541 aatcatttca aaatgcagtt atggaaggga tacgctatgg ttgcgaacaa ggattatatg
      601 gttggaatgt gacggattgt aaaatctgtt ttaagtacgg tttatactat agccctgtta
      661 gtactccagc agattttcgg atgcttactc ctattgtact ggagcaagcc tttagaaaag
      721 ctggaacaga attgttagag ccatatctta gttttaaagt ttatgcacca caggaatatc
      781 tttcacgggc atataacgat gctcccaaat attgtgcaaa tatcgtaaat actcaactga
      841 aaaataatga ggtcattatt attggagaaa ttcctgctcg atgtattcaa gattatcgca
      901 atgatttaac tttttttaca aatgggctta gtgtttgttt agcagagcta aaaggatatc
      961 aggttaccac tggcgaacct gtttgccaga cccgtcgtct aaatagtcgg atagataaag
     1021 taagatatat gttcaataaa ataacttagt gcgttttatg ttgttatata aatatggttt
     1081 cttattaaat aagatgaaat attctttaat atagatttga attaaagtgg aaaggaggag
     1141 attgttatta taaactacaa gtggatattg tgtcctattt gtggaaataa aacaagacta
     1201 cgaatacgag tggatactat acttaaaaat ttccctttat actgccccaa atgtaagaac
     1261 gaaactttaa ttaatgttca aaaaatgaat ataataacaa tcaaagagcc agacgccaag
     1321 acgcagagcc gataatttga gaaatgaaac tctcatctta tcggctcttt ttgtttatct
     1381 gaattttact gactagcctt caatatttct tgcttcattg ataccttttg ctagtgcttc
     1441 cattaaggat agttctttgt ctgtaaagct atccatgtat ttttctacct gtaaccttcg
     1501 agtgctttta atcaaattat ctgtaggtaa gaaaaattca tcaatagata catggagtaa
     1561 tgatacaaga tcatacagca cttgtgtact tgggtgttgt cctttgtttt ctatatttgt
     1621 taaataacgt gggtcaattt caatcattgt tcccacttgt tcacgagtga gaccccgttt
     1681 cattcgagcc tctttaatcg ctaaaccaac ggctctaaaa tcgtatttat cttctttttt
     1741 acgcatacta aatcacctct atacatttta ctgttcctat ataaccataa acaggtatag
     1801 aaaaacatgt tatatagttt atgagttcct atagaacact gtggaattta ttaatgcgat
     1861 gaatccaatt tcaaatagaa aggtcgctga ttttatttac ctatacaact ttataaaatt
     1921 tagtcatact cctagaaagt agataaaatt ggcgacttaa tggagggaaa agtcgccatg
     1981 agaaagataa tctgtcatct agttctctta attaagttct tatcaaaaaa acttatccac
     2041 ctgtactgga tagatatgac catcaatgtg gttttgcaga ttacatagat agaaaaatca
     2101 aagcatatga acagagaaaa caatctgttt atgtgctttt ttggtcactt aataaatatc
     2161 ttttaggatt tctcttcatt tatgcaacaa atcccccgtt cgtgtcgggg tttagtatga
     2221 agggagataa agaagcacat gccactccct ttcacgacag aaagggggtg aaaagcatga
     2281 aaccatcttc ttttcaagaa accatagaaa atcagtttga ctatatctgc aaacaagtta
     2341 ttgaagatga acgaaaagat tacttcaaac atctagacag actatcagca aaagaagtct
     2401 cgttttctga tatagataac taccttgtca actctttttc tactgttgat acgtacgtca
     2461 ctgatttcca actatttaaa ttatttggat taagaatcaa tgttgaaagt gatttattaa
     2521 gtgaagccct gcgtcatctt tcagagaaaa aacggaacat tattttactt cattacttta
     2581 tggatatgag tgatgtggag attgcggagt tactaaattt gaatcgttcg actgtttatc
     2641 gtcatcgaat aagtggacta gccatgatta aagaattcat gaaggagtgt aaagaatgaa
     2701 aacagcttat ccaagggttc ccttccccct cattgtaaag gcgacagatg gcgacgtgga
     2761 agcaattaat cagattgtta aacattatcg agggtatacc tcaaaacgtt cattacgtcg
     2821 catgacagac gaatatggaa attctcatat ggttattgat gaaaccctac gtggcagaat
     2881 ggaaacgaaa ctcatctcta agattttatc gttcgaaatt aaatagtccc attttttcgt
     2941 ggaagcgtgt cgaatcgtat ccacgcttcc cgatttggga ggtttgttat tccatcaaag
     3001 catattgtgt gttcagtagg ttttgatagg ctaacaagcc aaacgttctt tgacaaccaa
     3061 ataaaggcaa tcgaatacgt ttcggtaaga aaagagctga tgaactaaca cgccatgacc
     3121 tacaaaatta gtgagcgatt catgttagta attcgaaagt aatctttagc aggattgctg
     3181 ccatgacttt cttatcgtga taatgatact cccgtatagc catagtccga gcgttagaag
     3241 cgtcacaggc aatgggtacg gctacatgag aaccatgcag aagtgaaatt cctgtgagct
     3301 ttgctagagc tgttcgattg ctaagatatt cttctcttgt cagtgtatta ttataaaact
     3361 atttgatata attataggtg aatattggag ttttcctagc ctataattgg gaaaggagta
     3421 ataatgataa cggtcacaaa aaaggattta gttgagctag gatatggaac ttctttttca
     3481 gcagacatca taaaaaaagc aaaagaattg atgattacaa aagggcatat ctactatcaa
     3541 tctcgaaagc tagatagagt ccctcgtgaa gctgttgaag aaattctagg aattcggttt
     3601 tcaaatgaaa acaggtctga gtagtttttg cacagtaagg agtaaaaact atggttaaag
     3661 acccaataaa aaaagcaaag aatggaacct attattttcg tgcaaatcta ggttatgatt
     3721 ctaaagggaa aaaaattcaa aaatatcgta gtggattcac tactaaaaaa gaagcaagag
     3781 aagaatattc gaaactgcta ttgatgaaac cagaagaatt aagtgagaat aaggataaaa
     3841 tgacgtttaa acattatatc tttgaaattt tccttccatg gtataagaca caggtaaagc
     3901 tcagaacata tgaaaatcgc ttaccaacta ttaagaagca tttctcttat tttgataaaa
     3961 tggctgtttc cgatattgag cctattgatg tgcaaaattg gcaactaaaa ttatcaaaga
     4021 agtgtaagtc ttcttatgta agagctgttc aaggactatt ttcagttgct atggatcgag
     4081 caattgtcct tgggataacc accacaaatc catctaagat tattggcaat gtgaaaaagc
     4141 aaaagtctaa aattgaattt tggacaaaag aagaatttga aaaagtaatc tctctaattt
     4201 acaaagaaga ttactatcaa cactttttat ttatctctct gtggttttta tttatgactg
     4261 gaatgcgaat tggtgaagct actgccattc aatgggaaga tattgatttt gactcaggag
     4321 tactaaccat caacaaaaca ctctattaca agaatcaatc gaattataga tttgttgaac
     4381 caaaaacaaa ggcgagcgtt cgtcatattg tattagataa atgcacatta acttatttat
     4441 ccgaatggaa ggaagtacaa caaaatctaa ttcagacaga ctttgtaatg agctataacg
     4501 gtattcctac ccaaaaacat acactatcat atgctattga acgctatgct aagctggctg
     4561 gtatccatcg aatcagaatc catgggttac ggcattctca tgcttccttg ttaatcagta
     4621 tgggagaaaa tccacttatc attaaagatc gtctaggaca cgaagatatt gagacgactt
     4681 taggaacgta tggacatctt tatcctaaca gtaatttcga ggtagctaac aaattaaatg
     4741 gagccatttc ctttaaagaa gcaaaacaaa attatgatac ttcaccaaag aatcaattta
     4801 ctgtagacta cttgcgaaac aaagaaatga aaaaagtgca ataaaagtgc agtaaaaaga
     4861 taagaagagc cagaaaccct tggtataaga ggatttctag ctctcctaca actattccca
     4921 ctccactgtt gctggtggtt tagaagtgat gtcatacacg atacggttga cgtgggctac
     4981 ttcgtttacg atacgtacag agattttttg caagacttcc catgggatac gggcaaagtc
     5041 agcggtcatt ccgtcgattg aagttacagc acggataccg actgtgtagt cgtaagtacg
     5101 tccgtcaccc ataacaccga cagagcggat ccctggaaga acagtgaaat attgccagat
     5161 atcacggtca agtccagcag ctgcgatttc ttcacgcaag atagcatcag attcgcgtac
     5221 gatttctagc ttgtcttcag tgatttcgcc aagaacacga ataccaagac caggaccagg
     5281 gaatggctga cgccaaacga ttgaatcagg catgcctaac tgagtcccta attcacggac
     5341 ttcgtctttg aataatgtgt ttaatggttc gatcaattca aattgcatat cttctggcag
     5401 tccacctaca ttatggtgag atttgatcgt ctgtgctgtt tctgtaccag attcgataac
     5461 gtcagtatac aacgttcctt gtgctaggaa agagacgcct tcttcaccag caagttttgt
     5521 tgcttcgtca tcaaaaacat atacgaattc attcccaatg attttacgtt tttgttctgg
     5581 gtcagataca cctttcaact tgtctaagaa gcgatctctt gcatcgactt tgatgatgtt
     5641 caagccgaat tttccgccta gactttccat tacttgttcc gcttcgcctt tgcgtagcag
     5701 accgtggtca acaaagatag atgtcaattg gtcaccgatc gctttttgta aaagaacccc
     5761 aacgacacta gaatcaacgc cacctgaaag accaagcaag acttttttgt caccaacttg
     5821 ttcacggatt ttttctactt gcatatcgat aaagttatcc attgtccagt taccttcaca
     5881 gtgacaaaca tcaaaggcaa agtggcgcag caattcgatt ccgtattcgg aatgacgtac
     5941 ttctgcatgg aattggatac cataaaaatt acgtgttgtg tcttggatag aagcaatcgg
     6001 acaatctttg cttgttccga ctgtttcaaa gccttcagga actttagtta ccaagtcacc
     6061 atggctcatc catactgttt gttgttttgg tgtttcttta aacaagacag cttgatcgct
     6121 tgttacttct aacaaggctt tcccatattc gcggttttta gcaggctcta cggaaccgcc
     6181 aagtttgtac gtgatcaatt gcataccata gcaaatccct aatacaggaa tacctaaatt
     6241 gaagatctca ggatcgatcc caaatgcatt ctcatcatat acactgtttg gtccgccaga
     6301 aagaatgatt ccctttggat tcatcgcttt tacttcttct gcagtaatgc ggtggctcaa
     6361 taattcggaa aagactccaa gatcacgaat acgtcttgtg atcaattggt tatactgact
     6421 accgtagtct aatacgataa tcttttcaac gttcgtcata tcggcaacgt ttgtcaaatt
     6481 tattacccct atccctttaa attttatctc aaaatagtca aactatttta aaatgctaat
     6541 attttcgcat gaaaatcgaa tcgatgatat gattttcagt tttatggaga attatatcgg
     6601 ctcttcctcg tgtaggcaag atatattcct gtaaattttt caaattcaca tttttccata
     6661 catcttttgc cattttaaag gcttcttcac gatctccgat agcaaaacga taataataat
     6721 tctctggatt ttggaaagcc gtatccagta acgcaccaaa acgatccaaa taccattttt
     6781 cgatcagcac gggatcggca tcgacataga cagaaaaatc aaaaaagtcg ctgacgtaga
     6841 tttgctgatt cgcaggtaat tgaagcgtat tgatcccctc aacgatcaag atatcaggct
     6901 gctggatcaa ttcgtacttg tctggaatga tatcatacac atcatgtgag taaacaggta
     6961 cttttatctc ttcctgacca gattttacac ggttcaagaa atcgatcagc atctccatat
     7021 cataactttc aggaaatcct ttacggtcca tgattccacg ctcttttaat atacgatttg
     7081 gataaagaaa tccgtcagtc gtgatcagct gaacgtttct tcgtttgaag gtacgagaca
     7141 aaatcgtctg cagcagtctg gctgttgtac tttttccaac ggctacactt ccggcgatcc
     7201 cgataataaa aggcggtact tctacgtatt tatgaagaaa taaaccttta ctcaagaaca
     7261 aagattcaaa ttctttcata taaagataaa tcagatgagc aagaggtaca tagatatctc
     7321 gaacatcctg catggaaatg cggtcattca aacttttgat attatctagt tcatcttgtg
     7381 tcaaaggtgc ttgcccatta cgataaaatt ctcgccattc ttctcttgcc acacggtagt
     7441 agttcattgg atcattcata ttagcctcct gcgttctccc atcaatggaa ctattttaac
     7501 acaaaataaa cgcaaacccc accacttaag agagattgcc gatctttttg tataatcttt
     7561 ataatagaaa gaaacggagt cttattcttg acttgcgcac ggatacataa aaggatagac
     7621 tgttgtcatg aaagaaatga gaaggatgga agacatgaca aatcattact attctgaacg
     7681 cccagatacg gcgcacgatt ttgaacaatg ggcttttgag ttaaaaggca gaacctttca
     7741 atttgtaaca gattctggtg tattttcacg tgaaacagtg gattatggtt cacgtgtcct
     7801 gattgatgct ttcgattggg aagagttacc tgatgaagga aagatcttag atgtgggatg
     7861 cgggtatgga ccgattgggt tagctttggc atttgcgaca cagcggtttg ttgaaatggt
     7921 cgacattaat gaacgagcgg taagtctagc gcaaggaaac gcaaagcgta accaaatcga
     7981 acatgttgat atccatcaat cgaatatcta tgaagcagtt catgaagaaa cctatgcagc
     8041 tatcgtaagc aatccgccga tccgtgctgg aaaaaaagtt gtacatgaaa ttttgacagg
     8101 cgcatatcct cggttgaaga agggcggtac actgacaatt gtgatccaga agaaacaagg
     8161 agcgccgagt gcgcaaaaga aaatggaaga aacatttggt aatgcagaaa tcgtcacaaa
     8221 agataaagga tattatatca tcaaaagtgt gaaagaataa ctagctgaaa aatagtggag
     8281 cgacgaaaga gtggaactgg gcgtgcatgt acgggtacgt atcagttctt tttttgttga
     8341 gaagttttta aaaacaaaga actatttttt cttcaaaa
//
LOCUS       DACDAF010000260         7959 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.113, whole genome shotgun sequence.
ACCESSION   DACDAF010000260 DACDAF010000000
VERSION     DACDAF010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.113"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            128..1564
                     /locus_tag="IVZ69_002923"
     CDS             128..1564
                     /locus_tag="IVZ69_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HAP8184905.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="IVZ69_002924"
     CDS             1753..4200
                     /locus_tag="IVZ69_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HAP8184906.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="IVZ69_002925"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="IVZ69_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HAP8184907.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="IVZ69_002926"
     CDS             complement(5690..6793)
                     /locus_tag="IVZ69_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HAP8184908.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="IVZ69_002927"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="IVZ69_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HAP8184909.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2664 a         1359 c         1729 g         2207 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DACDAF010000261         7874 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.114, whole genome shotgun sequence.
ACCESSION   DACDAF010000261 DACDAF010000000
VERSION     DACDAF010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.114"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            322..2208
                     /locus_tag="IVZ69_002928"
     CDS             322..2208
                     /locus_tag="IVZ69_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HAP8184910.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            2220..3167
                     /locus_tag="IVZ69_002929"
     CDS             2220..3167
                     /locus_tag="IVZ69_002929"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HAP8184911.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            3187..3714
                     /locus_tag="IVZ69_002930"
     CDS             3187..3714
                     /locus_tag="IVZ69_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HAP8184912.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(3777..4430)
                     /locus_tag="IVZ69_002931"
     CDS             complement(3777..4430)
                     /locus_tag="IVZ69_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HAP8184913.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            4562..5404
                     /locus_tag="IVZ69_002932"
     CDS             4562..5404
                     /locus_tag="IVZ69_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HAP8184914.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            5562..6458
                     /locus_tag="IVZ69_002933"
     CDS             5562..6458
                     /locus_tag="IVZ69_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HAP8184915.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            6461..7174
                     /locus_tag="IVZ69_002934"
     CDS             6461..7174
                     /locus_tag="IVZ69_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HAP8184916.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            7194..7712
                     /gene="msrA"
                     /locus_tag="IVZ69_002935"
     CDS             7194..7712
                     /gene="msrA"
                     /locus_tag="IVZ69_002935"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HAP8184917.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            7709..>7874
                     /locus_tag="IVZ69_002936"
     CDS             7709..>7874
                     /locus_tag="IVZ69_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HAP8184918.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYL"
BASE COUNT         2845 a         1383 c         1602 g         2044 t
ORIGIN      
        1 gatgaatacg aagttgctga aaaaatcacg acgttttctg cgaacagcta tcgcaggaat
       61 atcaatttgt tagaatctta tacgatgaac aaaccatctg ataacttttc tttccgattt
      121 gcgtttcgag caaagtcaaa aaaaacgagt ccaataaaat aaaaaggtaa aaattttcaa
      181 gttttataaa aaacaaaaca tatcagaaca ggatcgaatc ggtcctgttc tttttttgag
      241 aacacaaaaa gaacaaatac caaaaaaatt ttcctgaagt tcactatttt tatgatacaa
      301 tatccaagat aaggagggaa catgttgaaa gaattaaaag taactgacct caaaaaaact
      361 tatggtgaaa aagatttgtt tgaccagatt tcttttttgg tccacgaaaa agaccgtatc
      421 gggttgattg ggacgaacgg gacgggtaaa acaagtctct taaatattat tgccggtatc
      481 gatagcagcg acggtgatcg gcaaacagtg ttttatccaa ctgattaccg tattggttat
      541 ctttctcaag cagctgaatt ttccgatgaa ttaactgttc tccaagcagt ctttcaagga
      601 aacagcccct tgatccaaac tgttcgagca tatgaggaag cattgatcga actaggggaa
      661 aacggagaag accctgatgt gcaaaaacgt tatgctaaag cagaagaaca aatgaataaa
      721 gaagatgctt ggactacaga taccaacgca aagattattt tgcaaaaatt aggaatcagt
      781 gaattagata aaaaaatcag tactttatca ggtggtcaga aaaaacgagt tagtctggcg
      841 caagtgttga ttgatgaacc cgatttacta ttactagacg aaccaacaaa ccatttagat
      901 tatgaagcga tcgagtggtt ggaaaactat ttgaaacaat accgtggcgc actattgatg
      961 gttacccacg atcgttattt tctagataga gtagcaaacc gaatcttcga actttcattt
     1021 ggaaaattat acgagtataa aggaaattat gaagcttacg tcttagaaaa agcagaacgt
     1081 gatcgtgtag aagtagaaca agaagaaaag cgcaagcggc tttataaaca ggaattagct
     1141 tggatgaggg ctggcgtaca ggcacgtggc accaagcagc aagcacggat caaccgtttc
     1201 gaagatctaa aggagaactt gtaccaagta aaccaagaag atgatttaga gctgaaccta
     1261 gcgacacaac gtttagggaa aaaagtactg gaaatcaaag atggcagtta ccgtataaat
     1321 gaccaaacac tgctagaaca tttagattta ttgattcaat ctcgggaaag actaggtatt
     1381 actggtaaaa atggtgcggg aaaatcgaca ttgcttaata ttctagctgg cagaattccc
     1441 ctggatagcg gtacaatgtc tatcggtgaa acggttcatc ttgcgtatta tacacaagaa
     1501 aatgaagaaa tggcaccaga taaacggatg attgcttact tacaagaagc tgctgaagaa
     1561 gcaaaaacag cagatggcag tcaaatcgga gtagcagaat tacttgaacg atttttattt
     1621 ccaagattta tgcatgggac actgataggc aaactttcag gcggagaaaa acgccggtta
     1681 tttttgttga aactgctgat tcagcaacct aatgttttat tattggatga accgaccaat
     1741 gatttggaca tagcaacatt gacgattttg gaagattatt ttagaagttt tccaggtgct
     1801 gtgatcactg tttcccatga ccgttatttc ttggacaagg tagcagataa gttattagta
     1861 ttccaaggaa acggaaaaca agaactttat tacggaaaca tgtccagtta tttactgaag
     1921 caaaaagaga cccagcagcc tgctgaaaaa gcgaaaccaa aaatacagag caaggaacct
     1981 gctgaaaaga agaaattatc ttacatggaa caaaaagaat gggaaacgat tgaagatgag
     2041 attgcagaac ttgaagaaaa aatctcattg ctccaagaag agatgaatca tcaaggagat
     2101 aatttcactc gattacaaga attgcaaaac gacgtatctg aaacagaagc acaacttgaa
     2161 gaaaaaatgg cacggtggga atacttgagt gaatgggtag aagattagga ggaaaaagga
     2221 tggaacaagc gtatcttgac ttaggaagaa aattgttgga agaagggcat cgtaaagaag
     2281 acagaacagg cacaggcaca ttaagcttat tcggatacca aatgcggttt gatctgcaaa
     2341 aagggtttcc tttgttaaca acgaaacgag taccttttgg attgatcaaa agcgaattgc
     2401 tttggttttt aaaaggagat acgaatatcc gctatctatt acaaaataaa aaccatattt
     2461 gggatgaatg ggcatttgaa cgctacatca aaagtccaga ctataatgga ccagatatga
     2521 ctgattttgg ccatagatgt ttgacagatc ctgaattcaa tgaagaatat aaaaagcaga
     2581 gcaagctttt ttgcgagaag atcctaaccg atgattcctt tgctgaaaca tacggcgatc
     2641 ttggacacat ctacggctat caatggcgtc actgggaaac aaaagacggt ggctttatcg
     2701 atcaaatcaa acaagtgatc gaagcaatca aaaagactcc tgattctaga agattgatcg
     2761 tttctgcatg gaatccggaa gatgttccta gcatggcttt gcctccttgt catacgatgt
     2821 ttcaatttta tgttcaagag ggacggctaa gctgccaatt gtatcaacgc agtggggatg
     2881 tgtttctagg cgttccgttc aacattgcaa gttatgcgtt gctgactcac ctaattgcac
     2941 atgaaacagg tttagcggtt ggcgaatttg ttcacacatt aggagatgct catctttata
     3001 tcaatcatat cgaacaaatg aaagaacaat tgagccgaga aatacgcgca tttccgactt
     3061 tagttttgaa tcaggaaaag cagtcagtat ttgattttga gatggaagat atccaattag
     3121 aaggatatga cccacatccg gcgatcaaag ctcctatcgc tgtttagaat cagaaaggat
     3181 gagaaaatgt tagctgcaat ttgggcacag gatgaaaacg gattgattgg aaaagaagac
     3241 cgtcttcctt ggcgtttgcc aaatgatctg aaattcttca aacaaatgac agaagcaaat
     3301 acactagtga tgggacgaaa aacattcgaa gggatgggta gccgtccgtt gccgaatcgt
     3361 cagacgattg ttttgacgag agattcttcc tataaagcag aaggcgtgca tgtcatgcat
     3421 agtgtggaag acgtgcttgc tctggaaaaa gaaacagacg gtatcttttt catcgctgga
     3481 gggtcagctg tttatcaaga atttctgcca ttttgtacga tattataccg tacagtcatc
     3541 catcatgtat tcgatggaga tgcttatttt ccacctgttg actggtctga ttggtcactg
     3601 atcaatacta gtcaaggaga aatggatgaa aaaaatcgtt atccgcatca atttgaaacg
     3661 tatcagcgta atgagaatcc tgtaaaaagc gggacaggcg aattgacgat ataaaaaagc
     3721 tatggataga ctagctgtta tttagagctg tcccatccat agctttattt tttttattaa
     3781 gtaaagaata aaacagagaa gtacataaaa cctgcaccta acataacaaa caaatgccaa
     3841 acaacatgca tatagcggat agaattcaag ctataaaaga atgcgcctat cgtgtaagaa
     3901 agcccgcctg ctaccatcaa aataacacca gtcattccaa gagagtgata aagaggaaca
     3961 gcagccacga cacagagcca ccccataaaa atatagatga tcgtagatac ttttgatact
     4021 ctctcccgtt tatgcaacgt caacgcttta tatataatgc caagaatcgc aaacaaccag
     4081 attaatacaa ataaagtcca acctagccat cctcggatac tcagcaaaca aaaaggagta
     4141 taacttcctg caatcaaaag aaaaatcgaa ctatgatcga atacttggaa cacctttttt
     4201 gcttttgtaa aaatcaatga atgaaacaaa gtagacgtta aaaataaaag aatcatcatc
     4261 gatccataga tagcataaga gacaatatgg agggaggaat gcaagtgggc accttttact
     4321 aaaagaacca ctagtcccgc gatactcaat ccagtcccaa ttccatgggt gactgcatta
     4381 aacacttcat ttaatatttc atacgttcga ttaaatttcg ttttttccat gaaaacggct
     4441 cctttactag gtgtaattaa tgaaaaatca ttatttgtct gttatactaa aaatagaaat
     4501 tgtcttacat gtagtttaac atgaataagg catcttgtta aagaaagaga gagagaaaat
     4561 aatgacaaat gtaaaaatcg taacagattc ttcatgtacg atggaaaaaa atgtacgcga
     4621 tgctttaggc attcgtgtca tgccgctatc catcatgatc gacggaacag tatatcccga
     4681 tgatgaccaa ctagacggcg aaagatttat ggaaatgatg gcgaaagcaa aaaatctgcc
     4741 caaaacaagc caaccaccaa ttggagaatt catctcgatg tatgatgagc taggagaaga
     4801 cggcagtgaa gtgatttcga tccatatgac aaaaggcttg agtggaacag tagaagcagc
     4861 aagacaagcc agtaatctaa caaaaacgaa agtaacggtt atcgacagtg ataccactga
     4921 ccaaggatta tcttttcagg taattcgagc agctgaatta gcaaaagaag gtaaaacagt
     4981 agagaaaatc cttgaagaag tcaaaaaagt acaagacaat acaaaattat acatcggaat
     5041 atccacacta gataacttgg taaaaggtgg aagaatcagc cgaacaactg gtttgctgtc
     5101 tagtgttttg aacatacgcg tggtgatgaa tttcgcccat tctgaattaa tccctgtaac
     5161 taaggggcga ggaaagaaaa cgttcgataa atggtttaat aatttgaaaa atgaactgaa
     5221 agaattgcca aatgtgcgac aaatcggtat ttcacatgcg gatgcaaaag aattggcgca
     5281 agaattcaaa gagggtttgc aagaattatt cccggacatg catatccctg tactgcatac
     5341 gaatccggtt atcgctacgc atactggtaa agacgcgttt gcaatcatgt attatgtaga
     5401 ttagtcgaaa agaggataag ccctcagcct gaaaggcttg cagcttattc tctttttctt
     5461 tataaaatta ggaaaataat tgttttcttt tttcataaag actacctttt tgataaaatt
     5521 tttgataaca ttagaaccaa tcgaatacaa gaggtgaaaa aatgaaatta acgaaacgac
     5581 atttgatcct cgttttgttc ccattattaa ttgcgatcat catctatgca ggtttagctg
     5641 cttctatacc gaaagctggc ccactaatga aaccagtaac tactgtgaga gaagatccaa
     5701 ataaaaaaga aaaacttcac tacatagcta tcggagattc gctgactgaa ggagtaggag
     5761 atcaaaccaa gcaaggagga ttcgttcccc ttgtcgcaaa tgatctaaaa gaccgttata
     5821 atttgaccgc ggttgaaaca gaaaactatg gtgtaaatgg tgaacgaagt gaccagatct
     5881 taaagcgagt aaaaacaaaa gaagaaattc gaaacaatat caaaacagct gattttatca
     5941 cactgactgt tggcggtaat gatttgatga aagttatcca aaataattta ttcgggttaa
     6001 cggtcaattc ctttaaaaag ccactgaaaa actatcagga aaatgtcaca gaactattgg
     6061 aagaatttcg atccctcaat aaaaccgcac ctatttacat tttaggcatc tacaatccat
     6121 tttatttgaa ctttcctgag atcactgaca tgcagacaat tgttaacaat tggaacaaag
     6181 gaacagaaac ggtgacaaaa aaaatgccga actgctactt tatcccaatc aatgatttgc
     6241 tttatcaagg attgaatcag gaagtaggtg tcacagaaga aggaacagat caaacaacta
     6301 gcacgacaga aaatctaaat ggcatcaaaa ataatgtgct ctatgaagaa gatcatttcc
     6361 atccaaataa tttaggttat caattgatgg caaatgcagt gagagatcag ctgatcgaga
     6421 cacaaaacca atggttagag aaggaggatg atcaataaac atgaaaacaa gatctgacgt
     6481 atcttcaaac aaaacaaaga aaacaaatta ctggaaattc gccttcctta tccttcttgg
     6541 ggtagtactt ggttcgaccg tatttttagg cagccgtatt tttgctaatc gggaaccaga
     6601 actcccagaa ataccagctc ttacggaaag acaaggagat cctgtcttaa cgatcaattc
     6661 aaataaagaa aaagtcaatc aaatcatcag ctttttcctt agtgagtatc aaaaagatag
     6721 tgatattgaa tataaatttt atttggaaaa tgaagcacta ctcaatggta ctttcgaagt
     6781 actaggtttt cctatcgatt tctatttata ttttgatccg tatgtgatgg aaaacggaaa
     6841 tgtccaacta aaagctagaa gtctttctat cggaacattg agtttgccaa tcaaagatgt
     6901 gatgaatatg atcaagagaa actataaatt accagattgg atcgaagtca atacagatga
     6961 tctgactatc atgcttaggt tggatcaatt ccgaatgcaa aacgggatgt atattaaagc
     7021 agataaaatc gacttagtaa atgatgacat tcggtttagt ctatatttgc caaaagatac
     7081 ctctgatgct tcaaacaact caaataccaa caaaactagc accagcagta ctgaaagcaa
     7141 gacaaaagaa aataaaaaat catcggatga gtagtattag agggggaatc ataatggaac
     7201 gagcaatatt tgcaggaggc tgcttctggt gtatgatcca gcctttcgac acgcttcctg
     7261 gtatccatac agtgatgtca ggatatactg gagggcatgt accagatccg acttatgaac
     7321 aagtaaaaag ccaaacgact ggacatacag aagcagtgga gattatctat gatccaacat
     7381 tgatttcata tgaacaatta gtagaacttt actggcagca aactgatcca actgacgctt
     7441 tcggacaatt cgaggatcgc ggtgacaatt atcgcccggt gatcttttat ttgacagaag
     7501 aacagcggat cattgctgaa aaaagtaaga aacagttagc tgaaagtgga cgtttcgaac
     7561 agccaatcgt tacaaaaatc gaaccagccc aaccatttta tctagcagaa gaagaccatc
     7621 aagagtatta taaaaagcat cctgaaaatt ttaaaagaaa ccatgcacgc cgggctgcct
     7681 ttatcgaaga aaattggagg aacgaagggt gaatcgaagc ttttttcatt atttaatgac
     7741 actgcgaggc ggtggcacac atgatgcttt atctgttttc gctacagaag ccggtaaaga
     7801 catccaattt cctaagcaca gctctagcta cgaagaaatt tctaattatc tggaactgaa
     7861 tgtcgactat ttgc
//
LOCUS       DACDAF010000262         3970 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.142, whole genome shotgun sequence.
ACCESSION   DACDAF010000262 DACDAF010000000
VERSION     DACDAF010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.142"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="IVZ69_002937"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="IVZ69_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAP8184919.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="IVZ69_002938"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="IVZ69_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HAP8184920.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIKKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1256 a          613 c          816 g         1285 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaagaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata atgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt
//
LOCUS       DACDAF010000263         3970 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.143, whole genome shotgun sequence.
ACCESSION   DACDAF010000263 DACDAF010000000
VERSION     DACDAF010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.143"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            22..1941
                     /gene="tet(M)"
                     /locus_tag="IVZ69_002939"
     CDS             22..1941
                     /gene="tet(M)"
                     /locus_tag="IVZ69_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019117172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HAP8184921.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLYPVYH
                     GSAKSNIGIEQLIEVITNKFYSSTYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            2039..3412
                     /gene="tet(L)"
                     /locus_tag="IVZ69_002940"
     CDS             2039..3412
                     /gene="tet(L)"
                     /locus_tag="IVZ69_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002387933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(L)"
                     /protein_id="HAP8184922.1"
                     /translation="MKCNECNRVKYNQILIWLCVLSFFSVLNEMVLNVSLPDIANDFN
                     KPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFF
                     SLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGM
                     IAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT
                     SYSISFLIVSVLSFLIFVKHIKKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVS
                     MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSV
                     SFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTS
                     FLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWLVTLNVY
                     KHSQRDF"
BASE COUNT         1255 a          613 c          817 g         1285 t
ORIGIN      
        1 ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat
       61 gcgggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta
      121 ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga
      181 attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata
      241 gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat
      301 ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt
      361 catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat
      421 ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta
      481 atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa
      541 caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa
      601 tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa ttgctccttg
      661 taccctgttt atcatggaag cgcaaaaagc aacataggga ttgagcagct tatagaagtg
      721 ataacgaata aattttattc atcaacatac agaaagaagt ctgaactttg cggaaatgtc
      781 ttcaaaattg aatattcgga agaaagacaa cgtcttgcat atgtacgcct ttatggcgga
      841 atcctgcatt tgcgggattc ggttagaata tcggaaaagg aaaaaataaa aattacagaa
      901 atgtatactt caataaatgg tgaattatgt aaaattgata aggcttattc cggggaaatt
      961 gttattttgc aaaatgagtt tttgaagcta aatagtgttc ttggagatac aaagctattg
     1021 ccacagagag agagaattga aaatccgctc cctctgctgc aaacaactgt tgaaccgagc
     1081 aaacctcaac aaagggaaat gttacttgat gcacttttag aaatctccga cagtgacccg
     1141 cttctacaat attatgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa
     1201 gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta
     1261 aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac
     1321 atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg
     1381 ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt
     1441 caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat
     1501 gtgacggatt gtaaaatctg ttttaagtat ggcttatact atagccctgt tagtacccca
     1561 gcagattttc ggatgcttgc tcctattgta ttggaacaag tcttaaaaaa agctggaaca
     1621 gaattgttag agccatatct tagttttaaa atttatgcgc cacaggaata tctttcacga
     1681 gcatacaacg atgctcctaa atattgtgcg aacatcgtag acactcaatt gaaaaataat
     1741 gaggtcattc ttagtggaga aatccctgct cggtgtattc aagaatatcg tagtgattta
     1801 actttcttta caaatggacg tagtgtttgt ttaacagagt taaaagggta ccatgttact
     1861 accggtgaac ctgtttgcca gccccgtcgt ccaaatagtc ggatagataa agtacgatat
     1921 atgttcaata aaataactta gtgtatttta tgttgttata taaatatggt ttcttgttaa
     1981 ataagatgaa atatttttta ataaagattt gaattaaagt gtaaaggagg aattaattat
     2041 gaagtgtaat gaatgtaaca gggttaaata caaccaaatt ttaatttggc tttgcgtttt
     2101 atcttttttt agcgtattaa atgaaatggt tttgaacgtc tcattacctg atattgcaaa
     2161 tgattttaat aaaccacctg cgagtacaaa ctgggtgaac acagccttta tgttaacctt
     2221 ttccattgga acagctgtat atggaaagct atctgatcaa ttaggcatca aaaggttact
     2281 cctatttgga attataataa attgtttcgg gtcggtaatt gggtttgttg gccattcttt
     2341 cttttcctta cttattatgg ctcgttttat tcaaggggct ggtgcagctg catttccagc
     2401 actcgtaatg gttgtagttg cgcgctatat tccaaaggaa aataggggta aagcatttgg
     2461 tcttattgga tcgatagtag ccatgggaga aggagtcggt ccagcgattg gtggaatgat
     2521 agcccattat attcattggt cctatcttct actcattcct atgataacaa ttatcactgt
     2581 tccgtttctt atgaaattat taaagaaaga agtaaggata aaaggtcatt ttgatatcaa
     2641 aggaattata ctaatgtctg taggcattgt attttttatg ttgtttacaa catcatatag
     2701 catttctttt cttatcgtta gcgtgctgtc attcctgata tttgtaaaac atatcaagaa
     2761 agtaacagat ccttttgttg atcccggatt agggaaaaat atacctttta tgattggagt
     2821 tctttgtggg ggaattatat ttggaacagt agcagggttt gtctctatgg ttccttatat
     2881 gatgaaagat gttcaccagc taagtactgc cgaaatcgga agtgtaatta ttttccctgg
     2941 aacaatgagt gtcattattt tcggctacat tggtgggata cttgttgata gaagaggtcc
     3001 tttatacgtg ttaaacatcg gagttacatt tctttctgtt agctttttaa ctgcttcctt
     3061 tcttttagaa acaacatcat ggttcatgac aattataatc gtatttgttt taggtgggct
     3121 ttcgttcacc aaaacagtta tatcaacaat tgtttcaagt agcttgaaac agcaggaagc
     3181 tggtgctgga atgagtttgc ttaactttac cagcttttta tcagagggaa caggtattgc
     3241 aattgtaggt ggtttattat ccataccctt acttgatcaa aggttgttac ctatggaagt
     3301 tgatcagtca acttatctgt atagtaattt gttattactt ttttcaggaa tcattgtcat
     3361 tagttggctg gttaccttga atgtatataa acattctcaa agggatttct aaatcgttaa
     3421 gggatcaact ttgggagaga gttcaaaatt gatccttttt ttataacagg aattcaaatc
     3481 tttttgttcc attaaagggc gcgattgctg aataaaagat acgagagacc tctcttgtat
     3541 cttttttatt ttgagtggtt ttgtccgtta cactagaaaa ccgaaagaca ataaaaattt
     3601 tattcttgct gagtctggct ttcggtaagc tagacaaaac ggacaaaata aaaattggca
     3661 agggtttaaa ggtggagatt ttttgagtga tcttctcaaa aaatactacc tgtcccttgc
     3721 tgatttttaa acgagcacga gagcaaaacc cccctttgct gaggtggcag agggcaggtt
     3781 tttttgtttc ttttttctcg taaaaaaaag aaaggtctta aaggttttat ggttttggtc
     3841 ggcactgccg acagcctcgc agagcacaca ctttatgaat ataaagtata atgtgttata
     3901 ctttacttgg aagtggttgc cggaaagagc gaaaatgcct cacatttgtg ccacctaaaa
     3961 aggagcgatt
//
LOCUS       DACDAF010000264         3277 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.154, whole genome shotgun sequence.
ACCESSION   DACDAF010000264 DACDAF010000000
VERSION     DACDAF010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3277
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.154"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            275..772
                     /gene="dfrG"
                     /locus_tag="IVZ69_002941"
     CDS             275..772
                     /gene="dfrG"
                     /locus_tag="IVZ69_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HAP8184923.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(844..2796)
                     /locus_tag="IVZ69_002942"
     CDS             complement(844..2796)
                     /locus_tag="IVZ69_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HAP8184924.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2803..3099)
                     /locus_tag="IVZ69_002943"
     CDS             complement(2803..3099)
                     /locus_tag="IVZ69_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HAP8184925.1"
                     /translation="MQIGVLKWLQFTKQKGVHFPMQFLEPKNKNAKSVDWEISEQVRV
                     IVKQYAEYAERTESEAVDEFLLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
BASE COUNT         1016 a          566 c          538 g         1157 t
ORIGIN      
        1 taagtagttc agttttggag tacaaaatga caaaatgtac ttcaaaatgg actacttttt
       61 tcattttaac ttacatacca aattacatac aaaatgattt ataaaatgca attgaaaatg
      121 ataattgaat gaaaatttgt gattttgtgg tattatgata atataactta tagaaaaaat
      181 tgcttattca actaacgggc aggataatga gaaaaggttt tttgatagaa ataagaaatt
      241 agatggtaaa ttagttaaaa aggctgtgtt ataaatgaaa gtttctttga ttgctgcgat
      301 ggataagaat agagtgattg gcaaagagaa tgacattcct tggaggattc ccaaggactg
      361 ggaatatgtt aaaaatacta caaagggaca tccgataata ttaggtagga agaaccttga
      421 atcaatcgga agagccttac ctgacagaag aaatattatt ctgacgagag ataaggggtt
      481 tacctttaat ggttgtgaaa ttgttcattc aatagaagat gtttttgagt tatgtaaaaa
      541 cgaagaagaa atttttattt tcggaggaga acagatttat aatttgtttt tcccttatgt
      601 tgagaaaatg tacatcacaa aaatacatca tgaattcgaa ggagatactt tttttccaga
      661 agtgaattat gaggaatgga atgaggtatt tgcccaaaaa gggataaaga atgataaaaa
      721 tccgtataac tactattttc atgtatatga aagaaaaaac ttattgagtt aacgggtgcg
      781 ttaattgaag aagaacagta aagataaagc acaagagctt gggattactc caagctcttt
      841 ttgtcatttg aaataaatta tatctttcca atcaaattgt ttatctgtaa tccctaatct
      901 ttgagcaggt gtcaaaacct ttttatccgc tgatttaaaa gggcgacaaa agttgtagta
      961 agttcttaga attgtaatcg caaattgagc atacttcgga ttgaagttag cgtaaatata
     1021 gctcttctta tcaccacgag ctgttgttaa tggtctttca agagatgata tataacgtct
     1081 tatctgttga ataaagctat tggtcgaatg gtcattaaca tttaatagca tctttgcgat
     1141 ttcgtttggt tccagagcag ataaatccgt tctacaatca actgaataaa atcctttatc
     1201 cttagtggct aatggatgtt tgatagggtt atcggcatat ttgcgatatc tttctccatc
     1261 tttactaata gcctcttcgt ggaattgatg acttgttagt aattcagtta gataatgaga
     1321 tgccaaagtc cgtagaaact ttgttttgaa tcctctgata tctccccaat cgagcagttc
     1381 tgcttttgct tgtccgaatt cttttaagca ttgttttctg cttttcgtct tgttaacttg
     1441 gcaaataaaa tgatgtgcat cgctcaacct taattctttc gtgaatactc tataaaaggc
     1501 gtttctaata gagaagtcat catcactaat cattcgccat tcgtcggcat taaccatttg
     1561 tttaattaac caatagtgag cagttgtagt ataaggagca tcaacattta aaccatcgac
     1621 aaatctactc ctattagtaa ttttccctaa ttcgtgaaga taagcattcc tattttcgct
     1681 atcgttagcg gatggttctt gtggataata agaccaatct aacctatcat ttttacgact
     1741 aaaagtattg agatggtctt ctttgaattt tcttgtatct tcatttaatt catccattga
     1801 aatattccaa tcataggcaa catcagaacg gaacacatat cttgataaga cctcagcaga
     1861 tacaactata tacgtttgca tattaaggtc ttcaaacccc gtatatttct ttgaaccttg
     1921 tcctttctta cggacgttat ttaggtagta gtgcatcttg tccgtattaa gccacatctc
     1981 gttaaatttc tttgtttgaa ggggttgtgt ctcatatcgt tctaaaaact ccaaacaacg
     2041 cctatacagc cactccagct tatgatagta ggttccaact ccaattccta aaatatcaca
     2101 agtacgactg actgaaaccc ttccaacaac catcttagcg aacattggaa gaatggtgtt
     2161 cttttgttgg tgataagtag tggtttcttc tctttttggt agaacattag tgaacttctt
     2221 acacgcctta cattgatagc gttgagattt gcccctactt ttcccccttt tgtaaaattg
     2281 cttcggctca ttgaatgggg ttgattcttc ttccgagcag ccttctttat gaaattgata
     2341 atctggctca acatcttgga tgctattgat ttctataagg cgtttaattt cttcaacaac
     2401 agaccaatta gataaagggg ttactgtaca gttttgcgat acacctctgc caataggatt
     2461 gtcattgcag tacatacctt tatgaccttt atctttggaa ctaccagtca ttttatatcg
     2521 acttggtttc ccttttacat ctttgaattt gtgctgttct ttcccaaaat tacaacaaaa
     2581 cggattgatg cagtaattat attgaatggg atattcagaa ccgttccatt taaaagacgt
     2641 tggcaagaac aacattttgt tataccttgt tgcaaatcgt tttggagtta ataaatcata
     2701 ttgtttagcc ctatctttta attcttcgtt tgaaatcgga attttaacat ctacaatttc
     2761 atcttccttc gtggctaatc ttttaagctt ggtcattgtc tatcaaccca ctctatcttt
     2821 gatacccatt ttttcaacaa tccgcttatt acttcgcttg ttggcaatcc attcaataaa
     2881 cttcttatcg tctaaaatgt tcaataagaa ttcatccact gcttcgcttt cagtacgctc
     2941 tgcatattca gcgtattgct taactatcac ccttacttgc tctgatattt cccaatccac
     3001 agacttagcg ttcttatttt ttggctcaag aaattgcata ggaaaatgca cccctttttg
     3061 cttagtaaat tgtaaccatt ttaacacacc aatttgcatt cctacaataa ttatttcacg
     3121 ttcgcatttt tatatacatt ttaacttaca ttttgtggtg taaattaaca acaaacgttg
     3181 atttaacaat aaaaaacgag tatcaaattc agttgcaatt tgatactcat ttaggtttac
     3241 attttcactt tttgtactcc aaaactgaac tacttaa
//
LOCUS       DACDAF010000265         1739 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.187, whole genome shotgun sequence.
ACCESSION   DACDAF010000265 DACDAF010000000
VERSION     DACDAF010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1739
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.187"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            49..960
                     /locus_tag="IVZ69_002944"
     CDS             49..960
                     /locus_tag="IVZ69_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-A"
                     /protein_id="HAP8184926.1"
                     /translation="MKKLFFLLLLLFLIYLGYDYVNEALFSQEKVEFQNYDQNPKEHL
                     ENSGTSENTQEKTITEEQVYQGNLLLINSKYPVRQESVKSDIVNLSKHDELINGYGLL
                     DSNIYMSKEIAQKFSEMVNDAVKGGVSHFIINSGYRDFDEQSVLYQEMGAEYALPAGY
                     SEHNSGLSLDVGSSLTKMERAPEGKWIEENAWKYGFILRYPEDKTELTGIQYEPWHIR
                     YVGLPHSAIMKEKNFVLEEYMDYLKEEKTISVSVNGEKYEIFYYPVTKNTTIHVPTNL
                     RYEISGNNIDGVIVTVFPGSTHTNSRR"
     gene            1113..1598
                     /gene="vanZ"
                     /locus_tag="IVZ69_002945"
     CDS             1113..1598
                     /gene="vanZ"
                     /locus_tag="IVZ69_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance protein VanZ-A"
                     /protein_id="HAP8184927.1"
                     /translation="MGKILSRGLLALYLVTLIWLVLFKLQYNILSVFNYHQRSLNLTP
                     FTATGNFREMIDNVIIFIPFGLLLNVNFKEIGFLPKFAFVLVLSLTFEIIQFIFAIGA
                     TDITDVITNTVGGFLGLKLYGLSNKHMNQKKLDRVIIFVGILLLVLLLVYRTHLRINY
                     V"
BASE COUNT          613 a          238 c          331 g          557 t
ORIGIN      
        1 caggaggaca atttatttac acaaaattat tgacgctccc gactgaaaat gaagaagttg
       61 ttttttttat tgttattgtt attcttaata tacttaggtt atgactacgt taatgaagca
      121 ctgttttctc aggaaaaagt cgaatttcaa aattatgatc aaaatcccaa agaacattta
      181 gaaaatagtg ggacttctga aaatacccaa gagaaaacaa ttacagaaga acaggtttat
      241 caaggaaatc tgctattaat caatagtaaa tatcctgttc gccaagaaag tgtgaagtca
      301 gatatcgtga atttatctaa acatgacgaa ttaataaatg gatacgggtt gcttgatagt
      361 aatatttata tgtcaaaaga aatagcacaa aaattttcag agatggtcaa tgatgctgta
      421 aagggtggcg ttagtcattt tattattaat agtggctatc gagactttga tgagcaaagt
      481 gtgctttacc aagaaatggg ggctgagtat gccttaccag caggttatag tgagcataat
      541 tcaggtttat cactagatgt aggatcaagc ttgacgaaaa tggaacgagc ccctgaagga
      601 aagtggatag aagaaaatgc ttggaaatac gggttcattt tacgttatcc agaggacaaa
      661 acagagttaa caggaattca atatgaacca tggcatattc gctatgttgg tttaccacat
      721 agtgcgatta tgaaagaaaa gaatttcgtt ctcgaggaat atatggatta cctaaaagaa
      781 gaaaaaacca tttctgttag tgtaaatggg gaaaaatatg agatctttta ttatcctgtt
      841 actaaaaata ccaccattca tgtgccgact aatcttcgtt atgagatatc aggaaacaat
      901 atagacggtg taattgtgac agtgtttccc ggatcaacac atactaattc aaggaggtaa
      961 ggatggcgga atgaaaccaa cgaaattaat gaacagcatt attgtactag cacttttggg
     1021 gtaacgttag ctttttaatt taaaacccac gttaactagg acattgctat actaatgata
     1081 caacttaaac aaaagaatta gaggaaatta tattgggaaa aatattatct agaggattgc
     1141 tagctttata tttagtgaca ctaatctggt tagtgttatt caaattacaa tacaatattt
     1201 tatcagtatt taattatcat caaagaagtc ttaacttgac tccatttact gctactggga
     1261 atttcagaga gatgatagat aatgttataa tctttattcc atttggcttg cttttgaatg
     1321 tcaattttaa agaaatcgga tttttaccta agtttgcttt tgtactggtt ttaagtctta
     1381 cttttgaaat aattcaattt atcttcgcta ttggagcgac agacataaca gatgtaatta
     1441 caaatactgt tggaggcttt cttggactga aattatatgg tttaagcaat aagcatatga
     1501 atcaaaaaaa attagacaga gttattattt ttgtaggtat acttttgctc gtattattgc
     1561 tcgtttaccg tacccattta agaataaatt acgtgtaaga tgtctaaatc aagcaatctg
     1621 atctttcata cacataaaga tattgaatga attggattag atggaaaacg ggatgtgggg
     1681 aaactcgccc gtaggtgtga agggttctgt tgcaaagttt taaatctact atcaaataa
//
LOCUS       DACDAF010000266         1032 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.223, whole genome shotgun sequence.
ACCESSION   DACDAF010000266 DACDAF010000000
VERSION     DACDAF010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.223"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            266..>1032
                     /gene="aph(2'')-I"
                     /locus_tag="IVZ69_002946"
     CDS             266..>1032
                     /gene="aph(2'')-I"
                     /locus_tag="IVZ69_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021424053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HAP8184928.1"
                     /translation="MKYLIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTN
                     KKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTM
                     SEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEK
                     DYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDF
                     IYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIV"
BASE COUNT          432 a           83 c          173 g          344 t
ORIGIN      
        1 gggattttat tctttattta aaactttgca acagaaccgt acaagatata ttaaattgat
       61 ttttgaattt ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa
      121 taatccaaga gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc
      181 agaacatgaa ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga
      241 tgataatgcc acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt
      301 caaagtagat agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa
      361 taatgaatac atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga
      421 aaaagcaata tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat
      481 tgaatattcg tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac
      541 ttttttaaca ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg
      601 agatattgcc agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg
      661 tactattgat aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta
      721 taatgattta actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc
      781 aacaacagtt tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct
      841 attgttagat ggcaataata gattaactgg aataattgat tttggagatt ctggaattat
      901 agatgaatat tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa
      961 ttttggagaa gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata
     1021 tcaagatata gt
//
LOCUS       DACDAF010000267          975 bp    DNA     linear   BCT 12-NOV-2020
DEFINITION  TPA_asm: Enterococcus faecium isolate UW13772
            SAMN11027251-rid9893333.guided.227, whole genome shotgun sequence.
ACCESSION   DACDAF010000267 DACDAF010000000
VERSION     DACDAF010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN11027251
            Sequence Read Archive: SRR10694393
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (23-MAY-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 23-MAY-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000743146.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000743146.1
            Genome Coverage       :: 156x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/24/2020 04:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2020-02-06.build4373
            Genes (total)                     :: 2,948
            CDSs (total)                      :: 2,880
            Genes (coding)                    :: 2,809
            CDSs (with protein)               :: 2,809
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (5S)
            partial rRNAs                     :: 1, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 57
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 71
            CDSs (without protein)            :: 71
            Pseudo Genes (ambiguous residues) :: 0 of 71
            Pseudo Genes (frameshifted)       :: 39 of 71
            Pseudo Genes (incomplete)         :: 24 of 71
            Pseudo Genes (internal stop)      :: 16 of 71
            Pseudo Genes (multiple problems)  :: 7 of 71
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..975
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN11027251-rid9893333.guided.227"
                     /isolate="UW13772"
                     /isolation_source="perianal swab"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="Germany: Bavaria"
                     /collection_date="2015"
                     /collected_by="Robert Koch Institut"
     gene            18..77
                     /gene="ermCL"
                     /locus_tag="IVZ69_002947"
     CDS             18..77
                     /gene="ermCL"
                     /locus_tag="IVZ69_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002497446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methylase leader peptide ErmCL"
                     /protein_id="HAP8184929.1"
                     /translation="MGIFSIFVINTVHYQPNKK"
     gene            137..871
                     /locus_tag="IVZ69_002948"
     CDS             137..871
                     /locus_tag="IVZ69_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011282421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(T)"
                     /protein_id="HAP8184930.1"
                     /translation="MNKKNIKDSQNFITSKHHINEILRNVHLNTNDNIIEIGSGKGHF
                     TFELAKRCNYVTAIEIDPKLCRITKNKLIEYENFQVINKDILQFKFPKNKSYKIYGNI
                     PYNISTDIIRKIVFESTATESYLIVEYGFAKRLLNTNRSLALFLMTEVDISILSKIPR
                     EYFHPKPRVNSSLIVLKRHPSKISLKDRKQYENFVMKWVNKEYIKLFSKNQFYQALKY
                     ARIDDLNNISFEQFLSLFNSYKLFNR"
BASE COUNT          398 a          128 c          132 g          317 t
ORIGIN      
        1 aaaaggagaa ttaatatatg ggcattttta gtatttttgt aatcaacaca gttcattatc
       61 aaccaaacaa aaaataagtg gttataatgg attgttaata taaacattca ttataacctc
      121 ataggagtgg gttataatga acaaaaaaaa tataaaagat agtcaaaact ttattacttc
      181 aaagcatcat ataaatgaaa ttttgagaaa tgtacattta aatacaaatg ataatattat
      241 tgagattggt tcagggaaag gtcatttcac gtttgaatta gctaaaaggt gtaattatgt
      301 aaccgccatt gaaatagatc ctaaattatg taggataact aaaaacaaac ttattgaata
      361 tgagaacttc caggttatca ataaagatat tttacaattt aagtttccta aaaataagtc
      421 atataagata tatggaaata taccctacaa tataagtaca gatataattc gaaaaattgt
      481 ttttgaaagc acagctacag aaagttattt aatagtggaa tatggatttg ctaaaaggtt
      541 gctaaataca aatcgttcac tagcactatt tttaatgaca gaagttgata tatccatatt
      601 aagtaaaatc cctagagaat actttcatcc aaaacctaga gttaatagct cgttaattgt
      661 attaaaaaga cacccttcaa aaatatcact caaagataga aaacaatatg aaaattttgt
      721 tatgaaatgg gttaacaaag aatacataaa actattttcc aaaaaccaat tttatcaagc
      781 cttaaaatat gcaagaattg acgatttaaa caatattagc tttgaacaat tcttgtctct
      841 tttcaatagc tataaattat ttaatagata agttaagggg tgcataaact gcatccctta
      901 acttatctta ttttgcttaa acaatcttgg cccgtaaact gcataactca tatgtaaatc
      961 gctccttttt aggtg
//
